locus-tag	class	description
GPW86_RS00010	COG0246	Mannitol dehydrogenase
GPW86_RS00015	COG1904	glucuronate isomerase
GPW86_RS00020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPW86_RS00025	COG0800	Aldolase
GPW86_RS00035	COG0583	DNA-binding transcription factor activity
GPW86_RS00045	COG1902	pentaerythritol trinitrate reductase activity
GPW86_RS00055	COG1132	(ABC) transporter
GPW86_RS00065	COG1902	pentaerythritol trinitrate reductase activity
GPW86_RS00075	COG1280	lysine exporter protein (LysE YggA)
GPW86_RS00080	COG2207	Transcriptional regulator
GPW86_RS00100	COG1846	Transcriptional regulator
GPW86_RS00105	COG1764	response to oxidative stress
GPW86_RS00110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPW86_RS00115	COG0697	spore germination
GPW86_RS00125	COG0700	Nucleoside recognition
GPW86_RS00130	COG3366	ferrous iron transmembrane transporter activity
GPW86_RS00135	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GPW86_RS00145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPW86_RS00160	COG2259	Doxx family
GPW86_RS00185	COG0363	glucosamine-6-phosphate deaminase activity
GPW86_RS00190	COG3385	transposase activity
GPW86_RS00205	COG4580	involved in the transport of maltose and maltodextrins
GPW86_RS00220	COG0840	transmembrane signaling receptor activity
GPW86_RS00230	COG0840	transmembrane signaling receptor activity
GPW86_RS00240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPW86_RS00245	COG1126	abc transporter atp-binding protein
GPW86_RS00255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPW86_RS00260	COG4597	amino acid ABC transporter
GPW86_RS00265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPW86_RS00270	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPW86_RS00270	COG2213	PTS system mannitol-specific
GPW86_RS00275	COG0246	Mannitol dehydrogenase
GPW86_RS00280	COG3722	fumarate hydratase activity
GPW86_RS00285	COG0673	inositol 2-dehydrogenase activity
GPW86_RS00315	COG2910	NAD(P)H-binding
GPW86_RS00325	COG0840	transmembrane signaling receptor activity
GPW86_RS00330	COG4221	oxidoreductase activity
GPW86_RS00340	COG1901	pseudouridine methyltransferase
GPW86_RS00345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPW86_RS00355	COG0531	amino acid
GPW86_RS00360	COG1982	Orn Lys Arg decarboxylase major
GPW86_RS00370	COG2197	response regulator
GPW86_RS00420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPW86_RS00445	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GPW86_RS00455	COG0259	pyridoxamine-phosphate oxidase activity
GPW86_RS00485	COG0745	RESPONSE REGULATOR receiver
GPW86_RS00505	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GPW86_RS00510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPW86_RS00515	COG0840	transmembrane signaling receptor activity
GPW86_RS00520	COG0835	chemotaxis
GPW86_RS00525	COG0835	chemotaxis
GPW86_RS00530	COG2198	Histidine kinase
GPW86_RS00530	COG0643	Histidine kinase
GPW86_RS00550	COG0601	transmembrane transport
GPW86_RS00555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPW86_RS00560	COG4608	Belongs to the ABC transporter superfamily
GPW86_RS00565	COG2194	sulfuric ester hydrolase activity
GPW86_RS00570	COG0642	Histidine kinase
GPW86_RS00575	COG0745	RESPONSE REGULATOR receiver
GPW86_RS00605	COG1444	tRNA N-acetyltransferase activity
GPW86_RS00645	COG0217	transcriptional regulatory protein
GPW86_RS00650	COG2084	Dehydrogenase
GPW86_RS00670	COG2909	trisaccharide binding
GPW86_RS00675	COG0058	SHG alpha-glucan phosphorylase activity
GPW86_RS00680	COG1640	4-alpha-glucanotransferase
GPW86_RS00685	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GPW86_RS00695	COG3501	Rhs element vgr protein
GPW86_RS00730	COG0471	metal ion transport
GPW86_RS00735	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPW86_RS00770	COG0671	phosphoesterase, PA-phosphatase related
GPW86_RS00780	COG3385	transposase activity
GPW86_RS00785	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GPW86_RS00795	COG1999	signal sequence binding
GPW86_RS00810	COG0786	glutamate:sodium symporter activity
GPW86_RS00830	COG1566	PFAM secretion protein HlyD family protein
GPW86_RS00840	COG3706	GGDEF domain
GPW86_RS00855	COG0813	purine-nucleoside phosphorylase activity
GPW86_RS00860	COG3272	Protein of unknown function (DUF1722)
GPW86_RS00870	COG0415	Belongs to the DNA photolyase family
GPW86_RS00875	COG1376	ErfK ybiS ycfS ynhG family protein
GPW86_RS00875	COG1388	LysM domain
GPW86_RS00885	COG0513	Belongs to the DEAD box helicase family
GPW86_RS00890	COG1770	oligopeptidase
GPW86_RS00920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPW86_RS00925	COG0573	inorganic phosphate transmembrane transporter activity
GPW86_RS00930	COG0581	inorganic phosphate transmembrane transporter activity
GPW86_RS00935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPW86_RS00940	COG0745	RESPONSE REGULATOR receiver
GPW86_RS00940	COG3706	GGDEF domain
GPW86_RS00955	COG0659	secondary active sulfate transmembrane transporter activity
GPW86_RS00965	COG0739	heme binding
GPW86_RS00970	COG5001	Diguanylate cyclase
GPW86_RS00970	COG3300	MHYT domain
GPW86_RS00980	COG2814	Major facilitator Superfamily
GPW86_RS01005	COG1301	dicarboxylic acid transport
GPW86_RS01020	COG1342	Belongs to the UPF0251 family
GPW86_RS01055	COG0673	inositol 2-dehydrogenase activity
GPW86_RS01065	COG2771	luxR family
GPW86_RS01065	COG2200	EAL domain
GPW86_RS01070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPW86_RS01080	COG0564	pseudouridine synthase activity
GPW86_RS01175	COG3501	Rhs element vgr protein
GPW86_RS01195	COG1869	D-ribose catabolic process
GPW86_RS01200	COG1129	ABC transporter
GPW86_RS01205	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPW86_RS01210	COG1879	ABC-type sugar transport system periplasmic component
GPW86_RS01215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPW86_RS01220	COG1609	Transcriptional regulator
GPW86_RS01230	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GPW86_RS01250	COG0584	glycerophosphoryl diester phosphodiesterase
GPW86_RS01255	COG2271	Major facilitator Superfamily
GPW86_RS01295	COG0579	oxidoreductase
GPW86_RS01305	COG0242	peptide deformylase activity
GPW86_RS01310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPW86_RS01310	COG1017	nitric oxide dioxygenase activity
GPW86_RS01315	COG1320	monovalent cation:proton antiporter activity
GPW86_RS01320	COG2212	antiporter activity
GPW86_RS01340	COG2111	Na H antiporter
GPW86_RS01340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GPW86_RS01350	COG0589	response to stress
GPW86_RS01355	COG0814	amino acid
GPW86_RS01360	COG3033	Beta-eliminating lyase
GPW86_RS01380	COG5001	Diguanylate cyclase
GPW86_RS01380	COG5002	protein histidine kinase activity
GPW86_RS01385	COG1278	Cold shock
GPW86_RS01400	COG2304	oxidoreductase activity
GPW86_RS01420	COG0714	Associated with various cellular activities
GPW86_RS01425	COG0840	transmembrane signaling receptor activity
GPW86_RS01440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPW86_RS01455	COG3604	Transcriptional regulator
GPW86_RS01460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPW86_RS01460	COG1017	nitric oxide dioxygenase activity
GPW86_RS01465	COG1278	Cold shock
GPW86_RS01470	COG3036	rescue of stalled ribosome
GPW86_RS01495	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GPW86_RS01495	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPW86_RS01510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPW86_RS01520	COG0516	GMP reductase activity
GPW86_RS01525	COG1204	response to ionizing radiation
GPW86_RS01535	COG0513	Belongs to the DEAD box helicase family
GPW86_RS01540	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPW86_RS01545	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GPW86_RS01555	COG0784	Response regulator, receiver
GPW86_RS01555	COG3437	response regulator, receiver
GPW86_RS01560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPW86_RS01560	COG4191	Histidine kinase
GPW86_RS01570	COG1757	Na H antiporter
GPW86_RS01575	COG2814	Major facilitator Superfamily
GPW86_RS01590	COG3240	lipase activity
GPW86_RS01600	COG0840	transmembrane signaling receptor activity
GPW86_RS01605	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPW86_RS01610	COG5380	lipid catabolic process
GPW86_RS01615	COG3291	Pkd domain containing protein
GPW86_RS01615	COG4412	M6 family metalloprotease domain protein
GPW86_RS01635	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPW86_RS01640	COG4605	iron ion homeostasis
GPW86_RS01645	COG4604	ABC transporter, ATP-binding protein
GPW86_RS01665	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPW86_RS01690	COG0745	RESPONSE REGULATOR receiver
GPW86_RS01700	COG3623	hexulose-6-phosphate isomerase
GPW86_RS01705	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GPW86_RS01710	COG0561	phosphatase activity
GPW86_RS01745	COG0366	Alpha amylase catalytic
GPW86_RS01765	COG0745	RESPONSE REGULATOR receiver
GPW86_RS01770	COG5000	phosphorelay sensor kinase activity
GPW86_RS01770	COG5002	protein histidine kinase activity
GPW86_RS01790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GPW86_RS01810	COG1686	Belongs to the peptidase S11 family
GPW86_RS01825	COG3338	carbonate dehydratase activity
GPW86_RS01830	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPW86_RS01830	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPW86_RS01835	COG0509	glycine decarboxylation via glycine cleavage system
GPW86_RS01840	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPW86_RS01850	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GPW86_RS01855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPW86_RS01865	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GPW86_RS01870	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GPW86_RS01995	COG0494	nUDIX hydrolase
GPW86_RS02210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPW86_RS02325	COG0346	lactoylglutathione lyase activity
GPW86_RS02335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPW86_RS02480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPW86_RS02480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPW86_RS02510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPW86_RS02510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPW86_RS02630	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPW86_RS02765	COG3041	Addiction module toxin RelE StbE family
GPW86_RS02785	COG3549	Plasmid maintenance system killer
GPW86_RS02790	COG3093	addiction module antidote protein HigA
GPW86_RS02900	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPW86_RS02960	COG0456	acetyltransferase
GPW86_RS03045	COG0384	phenazine biosynthesis protein PhzF
GPW86_RS03060	COG2161	toxin-antitoxin pair type II binding
GPW86_RS03065	COG4115	mRNA cleavage
GPW86_RS03170	COG1028	Short-chain dehydrogenase reductase Sdr
GPW86_RS03195	COG1555	photosystem II stabilization
GPW86_RS03195	COG1596	polysaccharide export
GPW86_RS03455	COG3040	lipid binding
GPW86_RS03560	COG3549	Plasmid maintenance system killer
GPW86_RS03565	COG3093	addiction module antidote protein HigA
GPW86_RS03585	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPW86_RS03590	COG1619	proteins homologs of microcin C7 resistance protein MccF
GPW86_RS03650	COG1943	Transposase
GPW86_RS03655	COG0545	Peptidyl-prolyl cis-trans isomerase
GPW86_RS03660	COG2885	chlorophyll binding
GPW86_RS03665	COG0840	transmembrane signaling receptor activity
GPW86_RS03670	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPW86_RS03675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPW86_RS03680	COG1621	beta-fructofuranosidase activity
GPW86_RS03690	COG1263	PTS System
GPW86_RS03690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPW86_RS03735	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPW86_RS03745	COG0640	Transcriptional regulator
GPW86_RS03770	COG0778	Nitroreductase
GPW86_RS03775	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GPW86_RS03780	COG0583	DNA-binding transcription factor activity
GPW86_RS03805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPW86_RS03840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPW86_RS03845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPW86_RS03855	COG2390	Transcriptional regulator
GPW86_RS03870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPW86_RS03880	COG0302	gtp cyclohydrolase
GPW86_RS03885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPW86_RS03885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPW86_RS03890	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GPW86_RS03895	COG1970	mechanosensitive ion channel activity
GPW86_RS03900	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GPW86_RS03910	COG1011	Hydrolase
GPW86_RS03915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPW86_RS03920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPW86_RS03930	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPW86_RS03935	COG1840	ABC-type Fe3 transport system, periplasmic component
GPW86_RS03985	COG4166	transmembrane transport
GPW86_RS03990	COG4174	ABC transporter (Permease)
GPW86_RS03995	COG4239	(ABC) transporter, permease
GPW86_RS04005	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPW86_RS04020	COG0625	glutathione transferase activity
GPW86_RS04040	COG2050	protein possibly involved in aromatic compounds catabolism
GPW86_RS04055	COG1943	Transposase
GPW86_RS04060	COG4771	TonB-dependent receptor
GPW86_RS04060	COG1629	transport
GPW86_RS04065	COG0583	DNA-binding transcription factor activity
GPW86_RS04070	COG0045	succinate-CoA ligase (ADP-forming) activity
GPW86_RS04070	COG1042	CoA-binding domain protein
GPW86_RS04070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPW86_RS04080	COG1181	Belongs to the D-alanine--D-alanine ligase family
GPW86_RS04090	COG0023	Translation Initiation Factor
GPW86_RS04140	COG4128	Pfam Zonular occludens toxin
GPW86_RS04165	COG0745	RESPONSE REGULATOR receiver
GPW86_RS04175	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GPW86_RS04180	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GPW86_RS04195	COG3706	GGDEF domain
GPW86_RS04255	COG2824	Alkylphosphonate utilization operon protein PhnA
GPW86_RS04260	COG3385	transposase activity
GPW86_RS04275	COG0737	Belongs to the 5'-nucleotidase family
GPW86_RS04280	COG3593	DNA synthesis involved in DNA repair
GPW86_RS04290	COG0583	DNA-binding transcription factor activity
GPW86_RS04295	COG2116	formate transmembrane transporter activity
GPW86_RS04300	COG3385	transposase activity
GPW86_RS04310	COG3038	cytochrome b561
GPW86_RS04320	COG2200	EAL domain
GPW86_RS04330	COG0586	Pfam SNARE associated Golgi protein
GPW86_RS04335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPW86_RS04340	COG0745	RESPONSE REGULATOR receiver
GPW86_RS04345	COG2205	protein histidine kinase activity
GPW86_RS04350	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GPW86_RS04350	COG0674	pyruvate-flavodoxin oxidoreductase activity
GPW86_RS04350	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GPW86_RS04350	COG1013	pyruvate-flavodoxin oxidoreductase activity
GPW86_RS04355	COG3158	transport of potassium into the cell
GPW86_RS04365	COG0523	cobalamin synthesis protein
GPW86_RS04370	COG0038	chloride channel
GPW86_RS04380	COG0156	8-amino-7-oxononanoate synthase activity
GPW86_RS04385	COG2205	protein histidine kinase activity
GPW86_RS04385	COG0784	Response regulator, receiver
GPW86_RS04390	COG0419	ATPase involved in DNA repair
GPW86_RS04395	COG0420	3'-5' exonuclease activity
GPW86_RS04400	COG1609	Transcriptional regulator
GPW86_RS04410	COG1105	Belongs to the carbohydrate kinase PfkB family
GPW86_RS04415	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPW86_RS04415	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPW86_RS04415	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GPW86_RS04420	COG0189	ligase activity
GPW86_RS04420	COG4067	protein conserved in archaea
GPW86_RS04430	COG0602	queuosine metabolic process
GPW86_RS04435	COG1328	CTP reductase activity
GPW86_RS04445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPW86_RS04450	COG0840	transmembrane signaling receptor activity
GPW86_RS04455	COG3069	C4-dicarboxylate transmembrane transporter activity
GPW86_RS04460	COG1760	l-serine dehydratase
GPW86_RS04465	COG2197	response regulator
GPW86_RS04470	COG3850	Histidine kinase
GPW86_RS04475	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPW86_RS04485	COG0243	molybdopterin cofactor binding
GPW86_RS04505	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPW86_RS04510	COG2197	response regulator
GPW86_RS04515	COG3851	Histidine kinase
GPW86_RS04520	COG2271	Major facilitator Superfamily
GPW86_RS04525	COG1840	ABC-type Fe3 transport system, periplasmic component
GPW86_RS04535	COG3842	ATPase activity
GPW86_RS04540	COG3243	poly(R)-hydroxyalkanoic acid synthase
GPW86_RS04550	COG0183	Belongs to the thiolase family
GPW86_RS04560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPW86_RS04565	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPW86_RS04580	COG3706	GGDEF domain
GPW86_RS04585	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPW86_RS04595	COG1979	alcohol dehydrogenase
GPW86_RS04610	COG4191	Histidine kinase
GPW86_RS04615	COG1840	ABC-type Fe3 transport system, periplasmic component
GPW86_RS04620	COG2271	Major facilitator Superfamily
GPW86_RS04625	COG0469	pyruvate kinase activity
GPW86_RS04635	COG1879	ABC-type sugar transport system periplasmic component
GPW86_RS04640	COG1803	Methylglyoxal synthase
GPW86_RS04645	COG1335	isochorismatase
GPW86_RS04650	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPW86_RS04655	COG0210	DNA helicase
GPW86_RS04660	COG1289	transmembrane transporter activity
GPW86_RS04690	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GPW86_RS04695	COG4149	molybdate abc transporter
GPW86_RS04700	COG0725	ABC transporter, periplasmic molybdate-binding protein
GPW86_RS04705	COG1492	cobalamin metabolic process
GPW86_RS04750	COG1917	Cupin 2, conserved barrel domain protein
GPW86_RS04750	COG4977	sequence-specific DNA binding
GPW86_RS04755	COG4771	TonB-dependent receptor
GPW86_RS04760	COG2814	Major facilitator Superfamily
GPW86_RS04765	COG2226	methyltransferase
GPW86_RS04765	COG3433	isochorismatase activity
GPW86_RS04765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPW86_RS04790	COG1021	2,3-dihydroxybenzoate-AMP ligase
GPW86_RS04795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPW86_RS04815	COG1132	(ABC) transporter
GPW86_RS04820	COG1132	(ABC) transporter
GPW86_RS04830	COG5002	protein histidine kinase activity
GPW86_RS04830	COG0784	Response regulator, receiver
GPW86_RS04835	COG1879	ABC-type sugar transport system periplasmic component
GPW86_RS04845	COG2827	Endonuclease containing a URI domain
GPW86_RS04850	COG3132	Protein of unknown function, DUF480
GPW86_RS04875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPW86_RS04880	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPW86_RS04885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPW86_RS04890	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GPW86_RS04895	COG0247	lactate metabolic process
GPW86_RS04900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPW86_RS04905	COG3118	belongs to the thioredoxin family
GPW86_RS04930	COG4160	amino acid transport
GPW86_RS04935	COG4215	(ABC) transporter
GPW86_RS04940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPW86_RS04945	COG1126	abc transporter atp-binding protein
GPW86_RS04955	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GPW86_RS04965	COG0494	nUDIX hydrolase
GPW86_RS04970	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GPW86_RS04980	COG1309	transcriptional regulator
GPW86_RS04985	COG0513	Belongs to the DEAD box helicase family
GPW86_RS04990	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GPW86_RS05000	COG0814	amino acid
GPW86_RS05005	COG0840	transmembrane signaling receptor activity
GPW86_RS05010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPW86_RS05015	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GPW86_RS05020	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GPW86_RS05025	COG1984	allophanate hydrolase subunit 2
GPW86_RS05040	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GPW86_RS05045	COG4181	ATPase activity
GPW86_RS05055	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPW86_RS05060	COG5001	Diguanylate cyclase
GPW86_RS05060	COG1716	ATPase activity
GPW86_RS05075	COG0484	heat shock protein binding
GPW86_RS05090	COG0546	phosphoglycolate phosphatase activity
GPW86_RS05105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPW86_RS05110	COG1368	sulfuric ester hydrolase activity
GPW86_RS05120	COG0513	Belongs to the DEAD box helicase family
GPW86_RS05125	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GPW86_RS05135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPW86_RS05145	COG3046	protein related to deoxyribodipyrimidine photolyase
GPW86_RS05150	COG3397	chitin binding
GPW86_RS05155	COG3227	Zinc metalloprotease (Elastase)
GPW86_RS05170	COG1166	arginine decarboxylase activity
GPW86_RS05185	COG2239	Acts as a magnesium transporter
GPW86_RS05195	COG0527	aspartate kinase activity
GPW86_RS05205	COG2154	pterin-4-alpha-carbinolamine dehydratase
GPW86_RS05210	COG3186	Phenylalanine-4-hydroxylase
GPW86_RS05215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPW86_RS05230	COG2264	protein methyltransferase activity
GPW86_RS05235	COG0583	DNA-binding transcription factor activity
GPW86_RS05250	COG2171	N-acyltransferase activity
GPW86_RS05255	COG1253	flavin adenine dinucleotide binding
GPW86_RS05260	COG1765	OsmC-like protein
GPW86_RS05290	COG1252	NADH dehydrogenase
GPW86_RS05295	COG0531	amino acid
GPW86_RS05300	COG3706	GGDEF domain
GPW86_RS05315	COG4989	oxidoreductase activity
GPW86_RS05320	COG0366	Alpha amylase catalytic
GPW86_RS05330	COG2067	long-chain fatty acid transport protein
GPW86_RS05335	COG2267	carboxylic ester hydrolase activity
GPW86_RS05345	COG3227	Zinc metalloprotease (Elastase)
GPW86_RS05350	COG3047	cAMP biosynthetic process
GPW86_RS05360	COG1686	Belongs to the peptidase S11 family
GPW86_RS05365	COG0557	exoribonuclease II activity
GPW86_RS05370	COG1278	Cold shock
GPW86_RS05380	COG3048	D-serine ammonia-lyase activity
GPW86_RS05405	COG2801	Transposase and inactivated derivatives
GPW86_RS05410	COG5002	protein histidine kinase activity
GPW86_RS05460	COG1063	alcohol dehydrogenase
GPW86_RS05465	COG0156	8-amino-7-oxononanoate synthase activity
GPW86_RS05470	COG2873	o-acetylhomoserine
GPW86_RS05480	COG0346	lactoylglutathione lyase activity
GPW86_RS05505	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPW86_RS05510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPW86_RS05515	COG0363	glucosamine-6-phosphate deaminase activity
GPW86_RS05520	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPW86_RS05545	COG1929	Belongs to the glycerate kinase type-1 family
GPW86_RS05550	COG2610	gluconate transmembrane transporter activity
GPW86_RS05555	COG3835	regulator
GPW86_RS05565	COG0748	coenzyme F420 binding
GPW86_RS05570	COG3721	Heme iron utilization protein
GPW86_RS05580	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GPW86_RS05585	COG0811	peptide transport
GPW86_RS05590	COG0848	biopolymer transport protein
GPW86_RS05595	COG4558	Periplasmic binding protein
GPW86_RS05600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPW86_RS05605	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GPW86_RS05640	COG3217	Mosc domain protein beta barrel domain protein
GPW86_RS05640	COG0633	Ferredoxin
GPW86_RS05640	COG3217	Mosc domain protein beta barrel domain protein
GPW86_RS05640	COG0633	Ferredoxin
GPW86_RS05645	COG0418	dihydroorotase activity
GPW86_RS05650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPW86_RS05655	COG2354	Protein conserved in bacteria
GPW86_RS05665	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPW86_RS05670	COG1278	Cold shock
GPW86_RS05695	COG3706	GGDEF domain
GPW86_RS05700	COG1349	DNA-binding transcription factor activity
GPW86_RS05715	COG3833	ABC-type maltose transport systems, permease component
GPW86_RS05720	COG1175	transmembrane transport
GPW86_RS05730	COG3842	ATPase activity
GPW86_RS05735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPW86_RS05750	COG0393	Putative heavy-metal-binding
GPW86_RS05755	COG2197	response regulator
GPW86_RS05760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPW86_RS05765	COG0784	Response regulator, receiver
GPW86_RS05765	COG0835	chemotaxis
GPW86_RS05770	COG1846	Transcriptional regulator
GPW86_RS05775	COG3706	GGDEF domain
GPW86_RS05810	COG0583	DNA-binding transcription factor activity
GPW86_RS05825	COG1741	Belongs to the pirin family
GPW86_RS05830	COG3123	guanosine phosphorylase activity
GPW86_RS05840	COG2211	Major facilitator Superfamily
GPW86_RS05855	COG1067	ATP-dependent peptidase activity
GPW86_RS05865	COG4172	Belongs to the ABC transporter superfamily
GPW86_RS05885	COG0583	DNA-binding transcription factor activity
GPW86_RS05890	COG1620	l-lactate permease
GPW86_RS05895	COG1304	FMN binding
GPW86_RS05905	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GPW86_RS05915	COG0840	transmembrane signaling receptor activity
GPW86_RS05935	COG2258	MOSC domain
GPW86_RS05940	COG0513	Belongs to the DEAD box helicase family
GPW86_RS05950	COG2186	Transcriptional regulator
GPW86_RS05960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GPW86_RS05990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPW86_RS06015	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GPW86_RS06015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPW86_RS06030	COG1061	Type III restriction enzyme res subunit
GPW86_RS06065	COG3120	sequence-specific DNA binding
GPW86_RS06070	COG1067	ATP-dependent peptidase activity
GPW86_RS06075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPW86_RS06100	COG0116	Belongs to the methyltransferase superfamily
GPW86_RS06100	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPW86_RS06110	COG0167	dihydroorotate dehydrogenase activity
GPW86_RS06125	COG0308	aminopeptidase N
GPW86_RS06140	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GPW86_RS06145	COG1956	GAF domain-containing protein
GPW86_RS06150	COG1132	(ABC) transporter
GPW86_RS06155	COG2995	paraquat-inducible protein a
GPW86_RS06160	COG3008	intermembrane lipid transfer
GPW86_RS06165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPW86_RS06165	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GPW86_RS06170	COG2996	Protein conserved in bacteria
GPW86_RS06185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPW86_RS06195	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GPW86_RS06210	COG0437	4 iron, 4 sulfur cluster binding
GPW86_RS06215	COG0243	molybdopterin cofactor binding
GPW86_RS06215	COG3383	formate dehydrogenase (NAD+) activity
GPW86_RS06245	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPW86_RS06250	COG0488	(ABC) transporter
GPW86_RS06255	COG3852	Histidine kinase
GPW86_RS06270	COG4662	Binding-protein-dependent transport system inner membrane component
GPW86_RS06275	COG3842	ATPase activity
GPW86_RS06280	COG0746	molybdenum cofactor guanylyltransferase activity
GPW86_RS06295	COG1940	carbohydrate kinase activity
GPW86_RS06310	COG0840	transmembrane signaling receptor activity
GPW86_RS06315	COG0791	NLP P60 protein
GPW86_RS06335	COG0534	Mate efflux family protein
GPW86_RS06345	COG1793	dna ligase
GPW86_RS06355	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GPW86_RS06360	COG0848	biopolymer transport protein
GPW86_RS06365	COG0811	peptide transport
GPW86_RS06370	COG0811	peptide transport
GPW86_RS06390	COG0395	ABC-type sugar transport system, permease component
GPW86_RS06395	COG3842	ATPase activity
GPW86_RS06400	COG1349	DNA-binding transcription factor activity
GPW86_RS06405	COG0584	glycerophosphoryl diester phosphodiesterase
GPW86_RS06410	COG2731	YhcH YjgK YiaL family protein
GPW86_RS06415	COG0251	oxidation-reduction process
GPW86_RS06420	COG1609	Transcriptional regulator
GPW86_RS06425	COG2723	6-phospho-beta-galactosidase activity
GPW86_RS06430	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GPW86_RS06435	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPW86_RS06450	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPW86_RS06495	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GPW86_RS06505	COG0583	DNA-binding transcription factor activity
GPW86_RS06525	COG0577	efflux transmembrane transporter activity
GPW86_RS06530	COG0577	efflux transmembrane transporter activity
GPW86_RS06530	COG1136	(ABC) transporter
GPW86_RS06535	COG1136	(ABC) transporter
GPW86_RS06535	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPW86_RS06540	COG1294	oxidase, subunit
GPW86_RS06545	COG1271	oxidase subunit
GPW86_RS06595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GPW86_RS06615	COG0753	catalase activity
GPW86_RS06625	COG3064	Membrane
GPW86_RS06635	COG3527	Alpha-acetolactate decarboxylase
GPW86_RS06650	COG2017	converts alpha-aldose to the beta-anomer
GPW86_RS06655	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPW86_RS06660	COG1085	galactose-1-phosphate uridylyltransferase
GPW86_RS06685	COG0745	RESPONSE REGULATOR receiver
GPW86_RS06685	COG3706	GGDEF domain
GPW86_RS06705	COG0784	Response regulator, receiver
GPW86_RS06705	COG0835	chemotaxis
GPW86_RS06715	COG4565	transcriptional regulatory protein
GPW86_RS06720	COG3290	protein histidine kinase activity
GPW86_RS06735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPW86_RS06755	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GPW86_RS06760	COG3063	Type IV pilus biogenesis stability protein PilW
GPW86_RS06775	COG1451	nucleotide metabolic process
GPW86_RS06785	COG0583	DNA-binding transcription factor activity
GPW86_RS06830	COG1538	Outer membrane efflux protein
GPW86_RS06840	COG0019	diaminopimelate decarboxylase activity
GPW86_RS06845	COG1748	Saccharopine dehydrogenase
GPW86_RS06870	COG4181	ATPase activity
GPW86_RS06875	COG0534	Mate efflux family protein
GPW86_RS06880	COG0702	epimerase
GPW86_RS06890	COG2814	Major facilitator Superfamily
GPW86_RS06895	COG1187	pseudouridine synthase activity
GPW86_RS06900	COG1061	Type III restriction enzyme res subunit
GPW86_RS06915	COG5002	protein histidine kinase activity
GPW86_RS06920	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GPW86_RS06925	COG5001	Diguanylate cyclase
GPW86_RS06925	COG3706	GGDEF domain
GPW86_RS06925	COG4251	negative regulation of phosphorylation
GPW86_RS06925	COG2203	Gaf domain
GPW86_RS06935	COG0840	transmembrane signaling receptor activity
GPW86_RS06970	COG4934	collagen metabolic process
GPW86_RS06985	COG0784	Response regulator, receiver
GPW86_RS06985	COG2205	protein histidine kinase activity
GPW86_RS06990	COG2239	Acts as a magnesium transporter
GPW86_RS07000	COG0814	amino acid
GPW86_RS07010	COG3313	Fe-S protein
GPW86_RS07020	COG4134	Bacterial extracellular solute-binding protein
GPW86_RS07025	COG4135	transport system, permease component
GPW86_RS07030	COG4136	ATPase activity
GPW86_RS07035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPW86_RS07040	COG0564	pseudouridine synthase activity
GPW86_RS07065	COG0733	neurotransmitter:sodium symporter activity
GPW86_RS07075	COG0626	cystathionine gamma-synthase activity
GPW86_RS07080	COG0626	cystathionine gamma-synthase activity
GPW86_RS07085	COG2818	Glycosylase
GPW86_RS07100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPW86_RS07115	COG1842	Phage shock protein A
GPW86_RS07120	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GPW86_RS07130	COG4168	peptide transport system, permease
GPW86_RS07135	COG4171	peptide transport system, permease
GPW86_RS07145	COG4172	Belongs to the ABC transporter superfamily
GPW86_RS07165	COG1227	inorganic diphosphatase activity
GPW86_RS07185	COG0243	molybdopterin cofactor binding
GPW86_RS07190	COG3005	denitrification pathway
GPW86_RS07195	COG4459	periplasmic nitrate reductase
GPW86_RS07200	COG2116	formate transmembrane transporter activity
GPW86_RS07210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPW86_RS07215	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPW86_RS07230	COG1607	acyl-coa hydrolase
GPW86_RS07235	COG2350	Protein conserved in bacteria
GPW86_RS07245	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPW86_RS07250	COG0583	DNA-binding transcription factor activity
GPW86_RS07270	COG5001	Diguanylate cyclase
GPW86_RS07275	COG1032	radical SAM domain protein
GPW86_RS07290	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GPW86_RS07295	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GPW86_RS07300	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GPW86_RS07305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPW86_RS07310	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPW86_RS07315	COG0745	RESPONSE REGULATOR receiver
GPW86_RS07320	COG3381	protein complex oligomerization
GPW86_RS07325	COG1609	Transcriptional regulator
GPW86_RS07330	COG3070	regulator of competence-specific genes
GPW86_RS07350	COG0297	glycogen (starch) synthase activity
GPW86_RS07355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPW86_RS07360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPW86_RS07370	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GPW86_RS07380	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GPW86_RS07385	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GPW86_RS07390	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPW86_RS07395	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPW86_RS07400	COG1960	acyl-CoA dehydrogenase activity
GPW86_RS07420	COG1012	belongs to the aldehyde dehydrogenase family
GPW86_RS07425	COG1309	transcriptional regulator
GPW86_RS07445	COG0668	transmembrane transport
GPW86_RS07450	COG2995	paraquat-inducible protein a
GPW86_RS07455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPW86_RS07455	COG3008	intermembrane lipid transfer
GPW86_RS07465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPW86_RS07495	COG0415	Belongs to the DNA photolyase family
GPW86_RS07505	COG4628	conserved protein (DUF2132)
GPW86_RS07510	COG3284	Transcriptional regulator
GPW86_RS07515	COG1012	belongs to the aldehyde dehydrogenase family
GPW86_RS07525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPW86_RS07530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPW86_RS07535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPW86_RS07545	COG2207	Transcriptional regulator
GPW86_RS07550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPW86_RS07550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPW86_RS07550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPW86_RS07555	COG1482	cell wall glycoprotein biosynthetic process
GPW86_RS07565	COG5002	protein histidine kinase activity
GPW86_RS07565	COG0784	Response regulator, receiver
GPW86_RS07575	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GPW86_RS07585	COG2885	chlorophyll binding
GPW86_RS07590	COG0823	Involved in the tonB-independent uptake of proteins
GPW86_RS07605	COG0811	peptide transport
GPW86_RS07610	COG0824	Thioesterase
GPW86_RS07615	COG3790	cyd operon protein YbgE
GPW86_RS07620	COG4890	Cyd operon protein YbgT
GPW86_RS07625	COG1294	oxidase, subunit
GPW86_RS07630	COG1271	oxidase subunit
GPW86_RS07635	COG2255	four-way junction helicase activity
GPW86_RS07640	COG0632	four-way junction helicase activity
GPW86_RS07650	COG0215	cysteine-tRNA ligase activity
GPW86_RS07655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPW86_RS07660	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPW86_RS07665	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPW86_RS07675	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPW86_RS07685	COG1199	ATP-dependent helicase activity
GPW86_RS07690	COG0730	response to heat
GPW86_RS07695	COG3923	Primosomal replication protein n
GPW86_RS07705	COG0708	Exodeoxyribonuclease III
GPW86_RS07710	COG4160	amino acid transport
GPW86_RS07715	COG4215	(ABC) transporter
GPW86_RS07735	COG1882	Formate acetyltransferase
GPW86_RS07745	COG0840	transmembrane signaling receptor activity
GPW86_RS07750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPW86_RS07760	COG3013	Belongs to the UPF0304 family
GPW86_RS07765	COG3385	transposase activity
GPW86_RS07770	COG2766	serine protein kinase
GPW86_RS07775	COG2718	Belongs to the UPF0229 family
GPW86_RS07780	COG2719	SpoVR family
GPW86_RS07785	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GPW86_RS07795	COG1663	tetraacyldisaccharide 4'-kinase activity
GPW86_RS07800	COG1132	(ABC) transporter
GPW86_RS07820	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPW86_RS07825	COG1136	(ABC) transporter
GPW86_RS07830	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPW86_RS07840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPW86_RS07865	COG1252	NADH dehydrogenase
GPW86_RS07895	COG0537	adenosine 5'-monophosphoramidase activity
GPW86_RS07910	COG2186	Transcriptional regulator
GPW86_RS07915	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPW86_RS07920	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GPW86_RS07925	COG1674	ftsk spoiiie
GPW86_RS07940	COG0686	Belongs to the AlaDH PNT family
GPW86_RS07950	COG0583	DNA-binding transcription factor activity
GPW86_RS07965	COG0284	orotidine-5'-phosphate decarboxylase activity
GPW86_RS07970	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GPW86_RS07975	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GPW86_RS07980	COG0776	regulation of translation
GPW86_RS07985	COG0539	negative regulation of cytoplasmic translation
GPW86_RS07990	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GPW86_RS07995	COG1555	photosystem II stabilization
GPW86_RS08000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPW86_RS08005	COG0776	regulation of translation
GPW86_RS08010	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPW86_RS08015	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPW86_RS08025	COG0544	peptidyl-prolyl cis-trans isomerase activity
GPW86_RS08035	COG4191	Histidine kinase
GPW86_RS08050	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GPW86_RS08055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPW86_RS08060	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GPW86_RS08075	COG3300	MHYT domain
GPW86_RS08075	COG5001	Diguanylate cyclase
GPW86_RS08120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPW86_RS08135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPW86_RS08155	COG0243	molybdopterin cofactor binding
GPW86_RS08160	COG3005	denitrification pathway
GPW86_RS08165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPW86_RS08175	COG2951	lytic endotransglycosylase activity
GPW86_RS08180	COG3100	YcgL domain-containing protein
GPW86_RS08185	COG0850	regulation of cytokinetic process
GPW86_RS08190	COG2894	cell division
GPW86_RS08195	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GPW86_RS08200	COG3015	lipoprotein NlpE involved in copper resistance
GPW86_RS08225	COG3135	benzoate transporter
GPW86_RS08235	COG1441	menaquinone biosynthetic process
GPW86_RS08245	COG0596	Alpha beta hydrolase
GPW86_RS08250	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GPW86_RS08255	COG1169	isochorismate synthase
GPW86_RS08260	COG0436	Aminotransferase
GPW86_RS08265	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GPW86_RS08270	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GPW86_RS08285	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GPW86_RS08290	COG0318	PFAM AMP-dependent synthetase and ligase
GPW86_RS08295	COG0596	Alpha beta hydrolase
GPW86_RS08310	COG1214	PFAM Peptidase M22, glycoprotease
GPW86_RS08325	COG0788	formyltetrahydrofolate deformylase activity
GPW86_RS08330	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPW86_RS08330	COG1902	pentaerythritol trinitrate reductase activity
GPW86_RS08335	COG0616	signal peptide processing
GPW86_RS08340	COG0252	asparaginase activity
GPW86_RS08345	COG3139	Protein of unknown function (DUF1315)
GPW86_RS08355	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPW86_RS08360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPW86_RS08365	COG0676	glucose-6-phosphate 1-epimerase activity
GPW86_RS08375	COG2226	methyltransferase
GPW86_RS08390	COG0835	chemotaxis
GPW86_RS08390	COG0784	Response regulator, receiver
GPW86_RS08395	COG1940	carbohydrate kinase activity
GPW86_RS08405	COG4667	esterase of the alpha-beta hydrolase superfamily
GPW86_RS08420	COG0733	neurotransmitter:sodium symporter activity
GPW86_RS08430	COG1263	PTS System
GPW86_RS08430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPW86_RS08435	COG0084	hydrolase, TatD family'
GPW86_RS08445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPW86_RS08450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPW86_RS08455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPW86_RS08460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPW86_RS08465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPW86_RS08470	COG1028	Short-chain dehydrogenase reductase Sdr
GPW86_RS08475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GPW86_RS08480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPW86_RS08485	COG0416	fatty acid biosynthetic process
GPW86_RS08490	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GPW86_RS08495	COG1399	metal-binding, possibly nucleic acid-binding protein
GPW86_RS08500	COG0424	maF-like protein
GPW86_RS08505	COG0564	pseudouridine synthase activity
GPW86_RS08510	COG1530	ribonuclease E activity
GPW86_RS08515	COG0659	secondary active sulfate transmembrane transporter activity
GPW86_RS08525	COG1454	alcohol dehydrogenase
GPW86_RS08525	COG1012	belongs to the aldehyde dehydrogenase family
GPW86_RS08530	COG2095	MarC family integral membrane protein
GPW86_RS08535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPW86_RS08540	COG1757	Na H antiporter
GPW86_RS08550	COG3081	Nucleoid-associated protein
GPW86_RS08560	COG3083	sulfuric ester hydrolase activity
GPW86_RS08575	COG0123	including yeast histone deacetylase and acetoin utilization protein
GPW86_RS08580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPW86_RS08585	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GPW86_RS08605	COG2853	Lipoprotein
GPW86_RS08615	COG4235	cytochrome complex assembly
GPW86_RS08615	COG3088	subunit of a heme lyase
GPW86_RS08620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPW86_RS08625	COG1138	Cytochrome C-type biogenesis protein
GPW86_RS08630	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GPW86_RS08640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPW86_RS08645	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPW86_RS08650	COG4133	protoheme IX ABC transporter activity
GPW86_RS08660	COG0835	chemotaxis
GPW86_RS08670	COG1192	Involved in chromosome partitioning
GPW86_RS08675	COG2201	protein-glutamate methylesterase activity
GPW86_RS08680	COG2198	Histidine kinase
GPW86_RS08680	COG0643	Histidine kinase
GPW86_RS08685	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GPW86_RS08700	COG0455	bacterial-type flagellum organization
GPW86_RS08715	COG2062	phosphohistidine phosphatase, SixA
GPW86_RS08730	COG0018	arginyl-trna synthetase
GPW86_RS08750	COG1918	ferrous iron import across plasma membrane
GPW86_RS08755	COG4977	sequence-specific DNA binding
GPW86_RS08760	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GPW86_RS08765	COG1121	(ABC) transporter
GPW86_RS08770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPW86_RS08780	COG0045	succinate-CoA ligase (ADP-forming) activity
GPW86_RS08785	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPW86_RS08800	COG1053	succinate dehydrogenase
GPW86_RS08805	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GPW86_RS08810	COG2009	succinate dehydrogenase
GPW86_RS08815	COG0372	Belongs to the citrate synthase family
GPW86_RS08820	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPW86_RS08830	COG0033	Phosphoglucomutase
GPW86_RS08835	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GPW86_RS08840	COG0596	Alpha beta hydrolase
GPW86_RS08855	COG1346	cytolysis
GPW86_RS08865	COG0583	DNA-binding transcription factor activity
GPW86_RS08875	COG0735	belongs to the Fur family
GPW86_RS08880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPW86_RS08885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPW86_RS08890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPW86_RS08895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPW86_RS08895	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GPW86_RS08900	COG0431	NADPH-dependent FMN reductase
GPW86_RS08910	COG3101	peptidyl-lysine hydroxylation
GPW86_RS08915	COG2860	membrane
GPW86_RS08920	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPW86_RS08925	COG2890	protein-(glutamine-N5) methyltransferase activity
GPW86_RS08940	COG1684	flagellar biosynthetic protein fliR
GPW86_RS08945	COG1987	bacterial-type flagellum assembly
GPW86_RS08970	COG1580	Controls the rotational direction of flagella during chemotaxis
GPW86_RS08995	COG1317	bacterial-type flagellum organization
GPW86_RS09000	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPW86_RS09010	COG1677	Flagellar hook-basal body complex protein FliE
GPW86_RS09015	COG2204	response regulator
GPW86_RS09020	COG4191	Histidine kinase
GPW86_RS09025	COG2204	response regulator
GPW86_RS09030	COG1516	flagellar protein fliS
GPW86_RS09040	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPW86_RS09045	COG1334	flagellar protein FlaG
GPW86_RS09050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPW86_RS09055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPW86_RS09060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPW86_RS09065	COG2837	iron assimilation
GPW86_RS09085	COG1393	Belongs to the ArsC family
GPW86_RS09095	COG1876	peptidase activity
GPW86_RS09105	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GPW86_RS09110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPW86_RS09120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPW86_RS09140	COG4783	chaperone-mediated protein folding
GPW86_RS09145	COG1393	Belongs to the ArsC family
GPW86_RS09165	COG2233	PERMEase
GPW86_RS09170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPW86_RS09175	COG0737	Belongs to the 5'-nucleotidase family
GPW86_RS09180	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GPW86_RS09185	COG2912	Transglutaminase-like superfamily
GPW86_RS09190	COG3094	Invasion gene expression up-regulator, SirB
GPW86_RS09195	COG2890	protein-(glutamine-N5) methyltransferase activity
GPW86_RS09200	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPW86_RS09205	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPW86_RS09210	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GPW86_RS09215	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPW86_RS09220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPW86_RS09225	COG0193	aminoacyl-tRNA hydrolase activity
GPW86_RS09230	COG0012	GTP binding
GPW86_RS09315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPW86_RS09320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPW86_RS09340	COG3951	Flagellar rod assembly protein muramidase FlgJ
GPW86_RS09340	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPW86_RS09345	COG1706	bacterial-type flagellum-dependent cell motility
GPW86_RS09350	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GPW86_RS09355	COG4786	Flagellar basal body rod
GPW86_RS09360	COG4787	bacterial-type flagellum-dependent cell motility
GPW86_RS09370	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPW86_RS09375	COG1558	bacterial-type flagellum-dependent cell motility
GPW86_RS09380	COG1815	bacterial-type flagellum-dependent cell motility
GPW86_RS09385	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPW86_RS09390	COG0835	chemotaxis
GPW86_RS09390	COG0784	Response regulator, receiver
GPW86_RS09425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPW86_RS09425	COG3433	isochorismatase activity
GPW86_RS09425	COG2226	methyltransferase
GPW86_RS09430	COG2375	cellular response to nickel ion
GPW86_RS09435	COG1629	transport
GPW86_RS09435	COG4774	siderophore transport
GPW86_RS09450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPW86_RS09455	COG2217	Heavy metal translocating P-type atpase
GPW86_RS09455	COG2608	mercury ion transmembrane transporter activity
GPW86_RS09470	COG3735	TraB family
GPW86_RS09485	COG2840	Smr protein MutS2
GPW86_RS09490	COG1187	pseudouridine synthase activity
GPW86_RS09495	COG3706	GGDEF domain
GPW86_RS09500	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPW86_RS09505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GPW86_RS09510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPW86_RS09515	COG0121	glutamine amidotransferase
GPW86_RS09520	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPW86_RS09525	COG1960	acyl-CoA dehydrogenase activity
GPW86_RS09535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPW86_RS09540	COG0328	RNA-DNA hybrid ribonuclease activity
GPW86_RS09545	COG2226	methyltransferase
GPW86_RS09550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPW86_RS09555	COG1388	LysM domain
GPW86_RS09555	COG0741	lytic transglycosylase activity
GPW86_RS09565	COG0347	Belongs to the P(II) protein family
GPW86_RS09570	COG3479	Phenolic acid decarboxylase
GPW86_RS09580	COG0037	tRNA processing
GPW86_RS09585	COG0825	malonyl-CoA metabolic process
GPW86_RS09590	COG0587	DNA-directed DNA polymerase activity
GPW86_RS09595	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPW86_RS09600	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPW86_RS09605	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPW86_RS09610	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPW86_RS09615	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPW86_RS09620	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GPW86_RS09630	COG0750	zinc metalloprotease
GPW86_RS09635	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GPW86_RS09640	COG0575	Belongs to the CDS family
GPW86_RS09645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPW86_RS09650	COG0233	cytoplasmic translational termination
GPW86_RS09655	COG0528	UMP kinase activity
GPW86_RS09660	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPW86_RS09665	COG0052	Belongs to the universal ribosomal protein uS2 family
GPW86_RS09670	COG0024	Methionine aminopeptidase
GPW86_RS09675	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GPW86_RS09685	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GPW86_RS09690	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GPW86_RS09695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPW86_RS09700	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GPW86_RS09715	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPW86_RS09715	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPW86_RS09720	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPW86_RS09725	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPW86_RS09730	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPW86_RS09745	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GPW86_RS09750	COG2252	PERMEase
GPW86_RS09760	COG0189	ligase activity
GPW86_RS09760	COG4067	protein conserved in archaea
GPW86_RS09765	COG0189	ligase activity
GPW86_RS09775	COG0733	neurotransmitter:sodium symporter activity
GPW86_RS09780	COG3706	GGDEF domain
GPW86_RS09790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPW86_RS09800	COG1477	protein flavinylation
GPW86_RS09805	COG2871	sodium ion transport
GPW86_RS09810	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPW86_RS09815	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPW86_RS09820	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPW86_RS09825	COG1805	sodium ion transport
GPW86_RS09830	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPW86_RS09835	COG0271	Belongs to the BolA IbaG family
GPW86_RS09840	COG2813	Specifically methylates the guanine in position
GPW86_RS09860	COG2211	Major facilitator Superfamily
GPW86_RS09870	COG1595	DNA-templated transcription, initiation
GPW86_RS09880	COG3248	Nucleoside-binding outer membrane protein
GPW86_RS09885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPW86_RS09890	COG0693	protein deglycase activity
GPW86_RS09895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPW86_RS09900	COG2166	iron-sulfur cluster assembly
GPW86_RS09905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GPW86_RS09910	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GPW86_RS09920	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPW86_RS09920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPW86_RS09930	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GPW86_RS09935	COG1074	ATP-dependent DNA helicase activity
GPW86_RS09955	COG3141	response to X-ray
GPW86_RS09960	COG2171	N-acyltransferase activity
GPW86_RS09970	COG0456	acetyltransferase
GPW86_RS09990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPW86_RS09995	COG1609	Transcriptional regulator
GPW86_RS10000	COG3250	beta-galactosidase activity
GPW86_RS10015	COG1022	Amp-dependent synthetase and ligase
GPW86_RS10020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPW86_RS10025	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPW86_RS10035	COG0560	Phosphoserine phosphatase
GPW86_RS10045	COG0813	purine-nucleoside phosphorylase activity
GPW86_RS10050	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPW86_RS10055	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GPW86_RS10060	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPW86_RS10070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPW86_RS10075	COG0084	hydrolase, TatD family'
GPW86_RS10090	COG1115	amino acid carrier protein
GPW86_RS10105	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPW86_RS10110	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GPW86_RS10115	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
GPW86_RS10120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPW86_RS10125	COG0083	homoserine kinase activity
GPW86_RS10145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPW86_RS10155	COG0745	RESPONSE REGULATOR receiver
GPW86_RS10160	COG5002	protein histidine kinase activity
GPW86_RS10160	COG2198	Histidine kinase
GPW86_RS10160	COG0784	Response regulator, receiver
GPW86_RS10165	COG5001	Diguanylate cyclase
GPW86_RS10165	COG4251	negative regulation of phosphorylation
GPW86_RS10165	COG2203	Gaf domain
GPW86_RS10165	COG3706	GGDEF domain
GPW86_RS10170	COG1242	4 iron, 4 sulfur cluster binding
GPW86_RS10175	COG0070	glutamate synthase
GPW86_RS10175	COG0067	glutamate synthase
GPW86_RS10175	COG0069	glutamate synthase activity
GPW86_RS10185	COG0070	glutamate synthase
GPW86_RS10185	COG0067	glutamate synthase
GPW86_RS10185	COG0069	glutamate synthase activity
GPW86_RS10190	COG0493	'glutamate synthase
GPW86_RS10200	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPW86_RS10210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPW86_RS10215	COG2860	membrane
GPW86_RS10220	COG0583	DNA-binding transcription factor activity
GPW86_RS10225	COG0730	response to heat
GPW86_RS10240	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GPW86_RS10245	COG0505	Belongs to the CarA family
GPW86_RS10255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GPW86_RS10260	COG0494	nUDIX hydrolase
GPW86_RS10265	COG0653	protein targeting
GPW86_RS10275	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GPW86_RS10280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPW86_RS10285	COG0849	cell division
GPW86_RS10290	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GPW86_RS10295	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPW86_RS10300	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPW86_RS10305	COG0772	Belongs to the SEDS family
GPW86_RS10310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPW86_RS10315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPW86_RS10320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GPW86_RS10325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPW86_RS10330	COG0768	penicillin binding
GPW86_RS10335	COG3116	cell division
GPW86_RS10340	COG0275	rRNA processing
GPW86_RS10350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPW86_RS10355	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPW86_RS10360	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GPW86_RS10365	COG2186	Transcriptional regulator
GPW86_RS10370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GPW86_RS10375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPW86_RS10380	COG4974	Belongs to the 'phage' integrase family
GPW86_RS10385	COG0716	FMN binding
GPW86_RS10405	COG4969	Belongs to the N-Me-Phe pilin family
GPW86_RS10410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPW86_RS10415	COG1459	type II secretion system
GPW86_RS10425	COG0237	dephospho-CoA kinase activity
GPW86_RS10430	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GPW86_RS10435	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GPW86_RS10440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPW86_RS10445	COG0187	DNA topoisomerase II activity
GPW86_RS10450	COG3150	esterase
GPW86_RS10460	COG3151	Protein conserved in bacteria
GPW86_RS10470	COG1538	Outer membrane efflux protein
GPW86_RS10475	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GPW86_RS10475	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GPW86_RS10485	COG0840	transmembrane signaling receptor activity
GPW86_RS10490	COG3025	triphosphatase activity
GPW86_RS10495	COG1392	Phosphate transport regulator
GPW86_RS10500	COG0306	phosphate transporter
GPW86_RS10505	COG4991	sh3 domain protein
GPW86_RS10520	COG0617	tRNA 3'-terminal CCA addition
GPW86_RS10525	COG0148	phosphopyruvate hydratase activity
GPW86_RS10530	COG0504	CTP synthase activity
GPW86_RS10535	COG3956	TIGRFAM MazG family protein
GPW86_RS10540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPW86_RS10545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPW86_RS10555	COG5001	Diguanylate cyclase
GPW86_RS10570	COG0736	holo-[acyl-carrier-protein] synthase activity
GPW86_RS10575	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GPW86_RS10580	COG1381	Involved in DNA repair and RecF pathway recombination
GPW86_RS10585	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPW86_RS10590	COG0571	ribonuclease III activity
GPW86_RS10595	COG0681	Belongs to the peptidase S26 family
GPW86_RS10600	COG0481	GTPase activity
GPW86_RS10605	COG3086	response to oxidative stress
GPW86_RS10610	COG3026	antisigma factor binding
GPW86_RS10615	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GPW86_RS10620	COG1595	DNA-templated transcription, initiation
GPW86_RS10625	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GPW86_RS10635	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GPW86_RS10640	COG0354	folic acid binding
GPW86_RS10650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPW86_RS10655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPW86_RS10665	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPW86_RS10675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPW86_RS10680	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GPW86_RS10685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPW86_RS10690	COG3385	transposase activity
GPW86_RS10695	COG0440	acetolactate synthase activity
GPW86_RS10700	COG0028	Belongs to the TPP enzyme family
GPW86_RS10705	COG1022	Amp-dependent synthetase and ligase
GPW86_RS10710	COG0583	DNA-binding transcription factor activity
GPW86_RS10725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPW86_RS10730	COG0473	3-isopropylmalate dehydrogenase activity
GPW86_RS10735	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPW86_RS10740	COG0066	3-isopropylmalate dehydratase activity
GPW86_RS10780	COG3437	response regulator, receiver
GPW86_RS10795	COG0795	lipopolysaccharide-transporting ATPase activity
GPW86_RS10800	COG0795	lipopolysaccharide-transporting ATPase activity
GPW86_RS10805	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPW86_RS10810	COG2927	DNA polymerase III (CHI subunit)
GPW86_RS10815	COG0525	valine-tRNA ligase activity
GPW86_RS10820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPW86_RS10825	COG0564	pseudouridine synthase activity
GPW86_RS10830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GPW86_RS10835	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GPW86_RS10840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPW86_RS10845	COG0540	Belongs to the ATCase OTCase family
GPW86_RS10850	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GPW86_RS10855	COG0251	oxidation-reduction process
GPW86_RS10860	COG0204	Acyl-transferase
GPW86_RS10865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPW86_RS10870	COG5007	Belongs to the BolA IbaG family
GPW86_RS10880	COG2854	intermembrane phospholipid transfer
GPW86_RS10885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPW86_RS10890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GPW86_RS10895	COG1127	ABC transporter
GPW86_RS10905	COG0517	IMP dehydrogenase activity
GPW86_RS10905	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GPW86_RS10920	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GPW86_RS10925	COG1137	ATPase activity
GPW86_RS10935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPW86_RS10940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPW86_RS10950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPW86_RS10955	COG2239	Acts as a magnesium transporter
GPW86_RS10960	COG0312	modulator of DNA gyrase
GPW86_RS10965	COG3028	Belongs to the UPF0307 family
GPW86_RS10970	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GPW86_RS10975	COG1178	ABC-type Fe3 transport system permease component
GPW86_RS10980	COG4143	(ABC) transporter
GPW86_RS10985	COG0163	prenyltransferase activity
GPW86_RS10990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPW86_RS10995	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GPW86_RS11000	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GPW86_RS11005	COG2105	PFAM AIG2 family protein
GPW86_RS11015	COG0729	surface antigen
GPW86_RS11020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPW86_RS11025	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GPW86_RS11040	COG1136	(ABC) transporter
GPW86_RS11060	COG0529	Catalyzes the synthesis of activated sulfate
GPW86_RS11065	COG2895	sulfate adenylyltransferase (ATP) activity
GPW86_RS11070	COG0175	sulfate reduction
GPW86_RS11075	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPW86_RS11075	COG1648	precorrin-2 dehydrogenase activity
GPW86_RS11080	COG0737	Belongs to the 5'-nucleotidase family
GPW86_RS11090	COG0513	Belongs to the DEAD box helicase family
GPW86_RS11095	COG2153	protein acetylation
GPW86_RS11100	COG0697	spore germination
GPW86_RS11105	COG3266	domain, Protein
GPW86_RS11105	COG3061	Opacity-associated protein A
GPW86_RS11110	COG0545	Peptidyl-prolyl cis-trans isomerase
GPW86_RS11120	COG0203	ribosomal protein L17
GPW86_RS11125	COG0202	RNA polymerase activity
GPW86_RS11130	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPW86_RS11135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPW86_RS11140	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPW86_RS11150	COG0201	protein transport
GPW86_RS11155	COG0200	Binds to the 23S rRNA
GPW86_RS11160	COG1841	ribosomal large subunit assembly
GPW86_RS11165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GPW86_RS11170	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPW86_RS11175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPW86_RS11180	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPW86_RS11185	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPW86_RS11190	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPW86_RS11195	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPW86_RS11200	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPW86_RS11205	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPW86_RS11210	COG0255	Belongs to the universal ribosomal protein uL29 family
GPW86_RS11215	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPW86_RS11220	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPW86_RS11225	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPW86_RS11230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPW86_RS11235	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPW86_RS11240	COG0089	rRNA binding
GPW86_RS11245	COG0088	Forms part of the polypeptide exit tunnel
GPW86_RS11250	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPW86_RS11255	COG0051	transcription antitermination factor activity, RNA binding
GPW86_RS11260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPW86_RS11265	COG0557	exoribonuclease II activity
GPW86_RS11270	COG3083	sulfuric ester hydrolase activity
GPW86_RS11275	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GPW86_RS11280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPW86_RS11290	COG1047	Peptidyl-prolyl cis-trans
GPW86_RS11305	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPW86_RS11310	COG0488	(ABC) transporter
GPW86_RS11320	COG0429	hydrolase of the alpha beta-hydrolase fold
GPW86_RS11330	COG3954	Phosphoribulokinase
GPW86_RS11335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPW86_RS11345	COG1012	belongs to the aldehyde dehydrogenase family
GPW86_RS11355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPW86_RS11385	COG0180	Tryptophanyl-tRNA synthetase
GPW86_RS11390	COG0546	phosphoglycolate phosphatase activity
GPW86_RS11395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPW86_RS11400	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GPW86_RS11410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPW86_RS11415	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GPW86_RS11445	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GPW86_RS11455	COG0678	peroxiredoxin activity
GPW86_RS11455	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPW86_RS11460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPW86_RS11470	COG0165	Argininosuccinate lyase
GPW86_RS11475	COG0137	argininosuccinate synthase activity
GPW86_RS11480	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPW86_RS11485	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPW86_RS11490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPW86_RS11495	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GPW86_RS11505	COG1045	serine acetyltransferase
GPW86_RS11510	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GPW86_RS11515	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GPW86_RS11520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPW86_RS11525	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GPW86_RS11530	COG1053	succinate dehydrogenase
GPW86_RS11535	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPW86_RS11540	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPW86_RS11545	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPW86_RS11550	COG3385	transposase activity
GPW86_RS11555	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPW86_RS11560	COG1509	lysine 2,3-aminomutase activity
GPW86_RS11570	COG0459	protein refolding
GPW86_RS11575	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPW86_RS11600	COG0149	triose-phosphate isomerase activity
GPW86_RS11610	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPW86_RS11620	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GPW86_RS11625	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GPW86_RS11630	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPW86_RS11635	COG1609	Transcriptional regulator
GPW86_RS11640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPW86_RS11645	COG0254	rRNA binding
GPW86_RS11650	COG0281	malic enzyme
GPW86_RS11655	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
GPW86_RS11660	COG0626	cystathionine gamma-synthase activity
GPW86_RS11665	COG0460	homoserine dehydrogenase
GPW86_RS11665	COG0527	aspartate kinase activity
GPW86_RS11670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPW86_RS11675	COG3074	FtsZ-dependent cytokinesis
GPW86_RS11685	COG0205	6-phosphofructokinase activity
GPW86_RS11690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPW86_RS11700	COG0745	RESPONSE REGULATOR receiver
GPW86_RS11705	COG2205	protein histidine kinase activity
GPW86_RS11715	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GPW86_RS11720	COG3030	protein affecting phage T7 exclusion by the F plasmid
GPW86_RS11725	COG3706	GGDEF domain
GPW86_RS11730	COG1027	Aspartate ammonia-lyase
GPW86_RS11735	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPW86_RS11745	COG4232	protein-disulfide reductase activity
GPW86_RS11765	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPW86_RS11770	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPW86_RS11775	COG0194	GDP metabolic process
GPW86_RS11780	COG1758	RNA polymerase activity
GPW86_RS11785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPW86_RS11790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPW86_RS11795	COG2233	PERMEase
GPW86_RS11805	COG0745	RESPONSE REGULATOR receiver
GPW86_RS11810	COG2199	diguanylate cyclase activity
GPW86_RS11815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPW86_RS11820	COG2183	response to ionizing radiation
GPW86_RS11830	COG0596	Alpha beta hydrolase
GPW86_RS11835	COG1040	competence protein
GPW86_RS11840	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GPW86_RS11840	COG0316	Belongs to the HesB IscA family
GPW86_RS11845	COG0494	nUDIX hydrolase
GPW86_RS11850	COG1218	3'(2'),5'-bisphosphate nucleotidase
GPW86_RS11860	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPW86_RS11865	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPW86_RS11870	COG3156	type II secretion system protein K
GPW86_RS11875	COG4795	General secretion pathway protein
GPW86_RS11880	COG2165	general secretion pathway protein
GPW86_RS11885	COG2165	general secretion pathway protein
GPW86_RS11890	COG2165	general secretion pathway protein
GPW86_RS11895	COG1459	type II secretion system
GPW86_RS11900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPW86_RS11910	COG3031	protein transport across the cell outer membrane
GPW86_RS11915	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GPW86_RS11920	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPW86_RS11925	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GPW86_RS11940	COG1490	D-aminoacyl-tRNA deacylase activity
GPW86_RS11950	COG1660	Displays ATPase and GTPase activities
GPW86_RS11965	COG0174	glutamine synthetase
GPW86_RS11975	COG3852	Histidine kinase
GPW86_RS11985	COG5001	Diguanylate cyclase
GPW86_RS11985	COG3300	MHYT domain
GPW86_RS11990	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPW86_RS12060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GPW86_RS12075	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPW86_RS12090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPW86_RS12095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPW86_RS12100	COG2177	Part of the ABC transporter FtsEX involved in
GPW86_RS12105	COG2884	Cell division ATP-binding protein ftsE
GPW86_RS12110	COG0552	protein localization to endoplasmic reticulum
GPW86_RS12115	COG0742	ribosomal rna small subunit methyltransferase
GPW86_RS12145	COG0783	Belongs to the Dps family
GPW86_RS12150	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPW86_RS12155	COG1280	lysine exporter protein (LysE YggA)
GPW86_RS12160	COG2267	carboxylic ester hydrolase activity
GPW86_RS12165	COG0561	phosphatase activity
GPW86_RS12180	COG3287	FIST C domain
GPW86_RS12180	COG2199	diguanylate cyclase activity
GPW86_RS12180	COG2200	EAL domain
GPW86_RS12185	COG1011	Hydrolase
GPW86_RS12190	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GPW86_RS12200	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPW86_RS12205	COG0019	diaminopimelate decarboxylase activity
GPW86_RS12215	COG1965	Belongs to the frataxin family
GPW86_RS12220	COG3072	Adenylate cyclase
GPW86_RS12230	COG0181	hydroxymethylbilane synthase activity
GPW86_RS12235	COG1587	Uroporphyrinogen-III synthase
GPW86_RS12240	COG2959	enzyme of heme biosynthesis
GPW86_RS12245	COG3071	HemY protein
GPW86_RS12250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPW86_RS12260	COG3078	GTPase activator activity
GPW86_RS12275	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GPW86_RS12280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPW86_RS12280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPW86_RS12295	COG0084	hydrolase, TatD family'
GPW86_RS12300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPW86_RS12310	COG0840	transmembrane signaling receptor activity
GPW86_RS12315	COG1580	Controls the rotational direction of flagella during chemotaxis
GPW86_RS12325	COG3161	chorismate lyase activity
GPW86_RS12330	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GPW86_RS12335	COG2937	Belongs to the GPAT DAPAT family
GPW86_RS12340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPW86_RS12350	COG0534	Mate efflux family protein
GPW86_RS12355	COG0805	protein transport
GPW86_RS12360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPW86_RS12365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPW86_RS12370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GPW86_RS12380	COG2226	methyltransferase
GPW86_RS12385	COG1322	Protein conserved in bacteria
GPW86_RS12395	COG2081	HI0933 family
GPW86_RS12405	COG1528	Iron-storage protein
GPW86_RS12415	COG0589	response to stress
GPW86_RS12420	COG0697	spore germination
GPW86_RS12430	COG0742	ribosomal rna small subunit methyltransferase
GPW86_RS12435	COG5002	protein histidine kinase activity
GPW86_RS12435	COG5001	Diguanylate cyclase
GPW86_RS12440	COG1522	sequence-specific DNA binding
GPW86_RS12460	COG0006	proline dipeptidase activity
GPW86_RS12460	COG0006	proline dipeptidase activity
GPW86_RS12470	COG2022	thiamine diphosphate biosynthetic process
GPW86_RS12475	COG2104	thiamine diphosphate biosynthetic process
GPW86_RS12480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPW86_RS12490	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GPW86_RS12495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPW86_RS12535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPW86_RS12545	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPW86_RS12550	COG0408	coproporphyrinogen oxidase activity
GPW86_RS12555	COG0009	L-threonylcarbamoyladenylate synthase
GPW86_RS12560	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPW86_RS12565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPW86_RS12570	COG0551	DNA topoisomerase type I activity
GPW86_RS12575	COG2922	Belongs to the Smg family
GPW86_RS12580	COG0758	DNA mediated transformation
GPW86_RS12585	COG1652	LysM domain
GPW86_RS12590	COG0242	peptide deformylase activity
GPW86_RS12595	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPW86_RS12600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPW86_RS12600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPW86_RS12605	COG0569	domain protein
GPW86_RS12610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPW86_RS12620	COG1272	protein, Hemolysin III
GPW86_RS12625	COG4326	sporulation control protein
GPW86_RS12635	COG3084	Protein conserved in bacteria
GPW86_RS12645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPW86_RS12650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPW86_RS12655	COG3385	transposase activity
GPW86_RS12660	COG0204	Acyl-transferase
GPW86_RS12665	COG0606	chelatase, subunit chli
GPW86_RS12680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPW86_RS12695	COG0604	alcohol dehydrogenase
GPW86_RS12705	COG0425	Belongs to the sulfur carrier protein TusA family
GPW86_RS12715	COG2119	membrane
GPW86_RS12720	COG0752	glycyl-tRNA synthetase alpha subunit
GPW86_RS12725	COG0751	glycine-tRNA ligase activity
GPW86_RS12730	COG3977	Valine--pyruvate aminotransferase
GPW86_RS12735	COG0071	Belongs to the small heat shock protein (HSP20) family
GPW86_RS12750	COG0187	DNA topoisomerase II activity
GPW86_RS12755	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPW86_RS12760	COG0592	DNA-directed DNA polymerase activity
GPW86_RS12765	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPW86_RS12780	COG1126	abc transporter atp-binding protein
GPW86_RS12785	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GPW86_RS12790	COG0594	ribonuclease P activity
GPW86_RS12795	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GPW86_RS12800	COG0706	membrane insertase activity
GPW86_RS12805	COG3385	transposase activity
GPW86_RS12810	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPW86_RS12815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPW86_RS12825	COG0445	tRNA wobble uridine modification
GPW86_RS12830	COG0357	Ribosomal RNA small subunit methyltransferase G
GPW86_RS12835	COG1192	Involved in chromosome partitioning
GPW86_RS12840	COG1475	DNA binding
GPW86_RS12845	COG3312	ion transport
GPW86_RS12850	COG0356	it plays a direct role in the translocation of protons across the membrane
GPW86_RS12860	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPW86_RS12865	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPW86_RS12870	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPW86_RS12875	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPW86_RS12880	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPW86_RS12885	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GPW86_RS12895	COG3385	transposase activity
GPW86_RS12900	COG2814	Major facilitator Superfamily
GPW86_RS12910	COG0183	Belongs to the thiolase family
GPW86_RS12915	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPW86_RS12915	COG1024	Enoyl-CoA hydratase
GPW86_RS12920	COG1739	Uncharacterized protein family UPF0029
GPW86_RS12925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPW86_RS13000	COG0583	DNA-binding transcription factor activity
GPW86_RS13005	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPW86_RS13010	COG2960	long-chain fatty acid transporting porin activity
GPW86_RS13020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPW86_RS13025	COG1309	transcriptional regulator
GPW86_RS13080	COG0747	negative chemotaxis
GPW86_RS13090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPW86_RS13100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPW86_RS13105	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GPW86_RS13115	COG0210	DNA helicase
GPW86_RS13120	COG1280	lysine exporter protein (LysE YggA)
GPW86_RS13130	COG0405	Gamma-glutamyltransferase
GPW86_RS13135	COG2962	Rard protein
GPW86_RS13140	COG0514	ATP-dependent DNA helicase (RecQ)
GPW86_RS13160	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPW86_RS13170	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPW86_RS13180	COG1561	YicC-like family, N-terminal region
GPW86_RS13185	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GPW86_RS13190	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPW86_RS13195	COG1560	Kdo2-lipid A biosynthetic process
GPW86_RS13200	COG1560	Kdo2-lipid A biosynthetic process
GPW86_RS13205	COG1309	transcriptional regulator
GPW86_RS13215	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPW86_RS13230	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GPW86_RS13235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GPW86_RS13245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GPW86_RS13250	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPW86_RS13255	COG0859	PFAM glycosyl transferase family 9
GPW86_RS13260	COG0463	Glycosyl transferase, family 2
GPW86_RS13265	COG0859	PFAM glycosyl transferase family 9
GPW86_RS13270	COG3642	lipopolysaccharide core region biosynthetic process
GPW86_RS13300	COG1519	Transferase
GPW86_RS13310	COG0859	PFAM glycosyl transferase family 9
GPW86_RS13325	COG0110	maltose O-acetyltransferase activity
GPW86_RS13335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPW86_RS13350	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPW86_RS13355	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPW86_RS13360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GPW86_RS13365	COG5433	transposase activity
GPW86_RS13385	COG0438	transferase activity, transferring glycosyl groups
GPW86_RS13390	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPW86_RS13400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GPW86_RS13410	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GPW86_RS13415	COG0668	transmembrane transport
GPW86_RS13420	COG1573	uracil-dna glycosylase
GPW86_RS13430	COG3068	Protein conserved in bacteria
GPW86_RS13435	COG1253	flavin adenine dinucleotide binding
GPW86_RS13440	COG0776	regulation of translation
GPW86_RS13450	COG0151	Belongs to the GarS family
GPW86_RS13455	COG0138	bifunctional purine biosynthesis protein purh
GPW86_RS13465	COG0789	Transcriptional regulator
GPW86_RS13470	COG3710	Transcriptional regulator
GPW86_RS13475	COG0531	amino acid
GPW86_RS13480	COG1982	Orn Lys Arg decarboxylase major
GPW86_RS13485	COG0840	transmembrane signaling receptor activity
GPW86_RS13505	COG0800	Aldolase
GPW86_RS13510	COG2610	gluconate transmembrane transporter activity
GPW86_RS13515	COG3265	gluconokinase activity
GPW86_RS13520	COG0129	dihydroxy-acid dehydratase activity
GPW86_RS13530	COG1609	Transcriptional regulator
GPW86_RS13535	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GPW86_RS13540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPW86_RS13545	COG2264	protein methyltransferase activity
GPW86_RS13550	COG0439	Biotin carboxylase
GPW86_RS13555	COG0511	ligase activity, forming carbon-carbon bonds
GPW86_RS13560	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GPW86_RS13585	COG2814	Major facilitator Superfamily
GPW86_RS13590	COG0784	Response regulator, receiver
GPW86_RS13590	COG2205	protein histidine kinase activity
GPW86_RS13600	COG0513	Belongs to the DEAD box helicase family
GPW86_RS13605	COG3118	belongs to the thioredoxin family
GPW86_RS13610	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPW86_RS13620	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GPW86_RS13665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPW86_RS13675	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GPW86_RS13685	COG1072	(Pantothenic acid kinase))
GPW86_RS13710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPW86_RS13715	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPW86_RS13720	COG0250	Participates in transcription elongation, termination and antitermination
GPW86_RS13725	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPW86_RS13730	COG0081	regulation of translation
GPW86_RS13735	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPW86_RS13740	COG0222	ribosome binding
GPW86_RS13745	COG0085	RNA polymerase activity
GPW86_RS13750	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPW86_RS13755	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GPW86_RS13765	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GPW86_RS13780	COG4942	peptidase
GPW86_RS13785	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPW86_RS13795	COG0471	metal ion transport
GPW86_RS13800	COG0688	phosphatidylethanolamine metabolic process
GPW86_RS13805	COG1162	GTPase activity
GPW86_RS13810	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GPW86_RS13855	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPW86_RS13860	COG0802	atpase or kinase
GPW86_RS13870	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPW86_RS13875	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPW86_RS13880	COG1923	regulation of RNA biosynthetic process
GPW86_RS13885	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPW86_RS13890	COG0330	HflC and HflK could
GPW86_RS13895	COG0330	HflC and HflK could
GPW86_RS13900	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GPW86_RS13905	COG2900	Belongs to the SlyX family
GPW86_RS13915	COG0545	Peptidyl-prolyl cis-trans isomerase
GPW86_RS13920	COG2964	Protein conserved in bacteria
GPW86_RS13925	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GPW86_RS13930	COG2923	Belongs to the DsrF TusC family
GPW86_RS13940	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GPW86_RS13945	COG0049	tRNA binding
GPW86_RS13950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPW86_RS13955	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPW86_RS13960	COG2906	2 iron, 2 sulfur cluster binding
GPW86_RS13970	COG0360	Binds together with S18 to 16S ribosomal RNA
GPW86_RS13975	COG2965	DNA replication, synthesis of RNA primer
GPW86_RS13980	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GPW86_RS13985	COG0359	binds to the 23S rRNA
GPW86_RS13995	COG0305	Participates in initiation and elongation during chromosome replication
GPW86_RS14000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPW86_RS14005	COG0432	Pfam Uncharacterised protein family UPF0047
GPW86_RS14010	COG0166	Belongs to the GPI family
GPW86_RS14025	COG0735	belongs to the Fur family
GPW86_RS14140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPW86_RS14165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPW86_RS14170	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPW86_RS14175	COG0175	sulfate reduction
GPW86_RS14245	COG1410	methionine synthase
GPW86_RS14245	COG0646	methionine synthase
GPW86_RS14250	COG0527	aspartate kinase activity
GPW86_RS14255	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPW86_RS14265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPW86_RS14280	COG0629	single-stranded DNA binding
GPW86_RS14285	COG2199	diguanylate cyclase activity
GPW86_RS14285	COG2200	EAL domain
GPW86_RS14310	COG3267	Type II secretory pathway component ExeA
GPW86_RS14310	COG3409	Peptidoglycan-binding domain 1 protein
GPW86_RS14320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPW86_RS14325	COG1459	type II secretion system
GPW86_RS14370	COG1077	Cell shape determining protein MreB Mrl
GPW86_RS14375	COG1792	Involved in formation and maintenance of cell shape
GPW86_RS14380	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GPW86_RS14385	COG0424	maF-like protein
GPW86_RS14390	COG1530	ribonuclease E activity
GPW86_RS14395	COG3164	Protein of unknown function
GPW86_RS14400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPW86_RS14405	COG0312	modulator of DNA gyrase
GPW86_RS14415	COG3039	Transposase
GPW86_RS14420	COG2235	arginine
GPW86_RS14440	COG0589	response to stress
GPW86_RS14455	COG1438	arginine binding
GPW86_RS14460	COG0039	L-malate dehydrogenase activity
GPW86_RS14465	COG0531	amino acid
GPW86_RS14470	COG0142	geranyltranstransferase activity
GPW86_RS14475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GPW86_RS14480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GPW86_RS14485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPW86_RS14490	COG2966	Psort location CytoplasmicMembrane, score
GPW86_RS14495	COG3610	response to peptide
GPW86_RS14505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GPW86_RS14510	COG2967	ApaG domain
GPW86_RS14515	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GPW86_RS14520	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GPW86_RS14525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPW86_RS14530	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GPW86_RS14535	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPW86_RS14565	COG0840	transmembrane signaling receptor activity
GPW86_RS14590	COG0741	lytic transglycosylase activity
GPW86_RS14595	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GPW86_RS14600	COG1194	a g-specific adenine glycosylase
GPW86_RS14605	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GPW86_RS14610	COG2066	Belongs to the glutaminase family
GPW86_RS14615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPW86_RS14620	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPW86_RS14635	COG0762	integral membrane protein
GPW86_RS14640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPW86_RS14645	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPW86_RS14665	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPW86_RS14670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPW86_RS14675	COG1678	Uncharacterized ACR, COG1678
GPW86_RS14680	COG0189	ligase activity
GPW86_RS14685	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GPW86_RS14690	COG2356	endonuclease I
GPW86_RS14695	COG3091	SprT-like family
GPW86_RS14700	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPW86_RS14705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPW86_RS14710	COG0583	DNA-binding transcription factor activity
GPW86_RS14715	COG4771	TonB-dependent receptor
GPW86_RS14720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPW86_RS14725	COG0126	phosphoglycerate kinase activity
GPW86_RS14730	COG0191	fructose-bisphosphate aldolase activity
GPW86_RS14740	COG0668	transmembrane transport
GPW86_RS14745	COG1279	arginine transmembrane transporter activity
GPW86_RS14750	COG0583	DNA-binding transcription factor activity
GPW86_RS14760	COG0469	pyruvate kinase activity
GPW86_RS14765	COG1349	DNA-binding transcription factor activity
GPW86_RS14770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GPW86_RS14775	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPW86_RS14870	COG2003	Belongs to the UPF0758 family
GPW86_RS14900	COG0582	viral genome integration into host DNA
GPW86_RS14910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPW86_RS14915	COG0358	DNA primase activity
GPW86_RS14920	COG1610	YqeY-like protein
GPW86_RS14925	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GPW86_RS14940	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GPW86_RS14945	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPW86_RS14950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPW86_RS14955	COG1968	undecaprenyl-diphosphatase activity
GPW86_RS14960	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GPW86_RS14965	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPW86_RS14970	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GPW86_RS14975	COG0585	pseudouridine synthase activity
GPW86_RS14980	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GPW86_RS14985	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GPW86_RS14990	COG4942	peptidase
GPW86_RS14990	COG1388	LysM domain
GPW86_RS14995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPW86_RS15000	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPW86_RS15020	COG4208	sulfate ABC transporter
GPW86_RS15025	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GPW86_RS15035	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPW86_RS15040	COG2137	regulation of response to DNA damage stimulus
GPW86_RS15045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPW86_RS15050	COG0527	aspartate kinase activity
GPW86_RS15055	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GPW86_RS15100	COG3630	sodium ion export across plasma membrane
GPW86_RS15105	COG5016	pyruvate
GPW86_RS15105	COG0511	ligase activity, forming carbon-carbon bonds
GPW86_RS15110	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPW86_RS15120	COG1238	metal cluster binding
GPW86_RS15125	COG0612	Peptidase, M16
GPW86_RS15135	COG1854	S-ribosylhomocysteine lyase activity
GPW86_RS15140	COG4536	flavin adenine dinucleotide binding
GPW86_RS15145	COG4137	Cytochrome C assembly protein
GPW86_RS15150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPW86_RS15155	COG0228	four-way junction DNA binding
GPW86_RS15160	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPW86_RS15165	COG0336	Belongs to the RNA methyltransferase TrmD family
GPW86_RS15170	COG0335	large ribosomal subunit rRNA binding
GPW86_RS15175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPW86_RS15180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPW86_RS15190	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GPW86_RS15195	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPW86_RS15200	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GPW86_RS15205	COG0723	plastoquinol--plastocyanin reductase activity
GPW86_RS15210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GPW86_RS15215	COG2857	Cytochrome c1
GPW86_RS15220	COG0625	glutathione transferase activity
GPW86_RS15225	COG2969	positive regulation of protein catabolic process
GPW86_RS15230	COG2823	Periplasmic or secreted lipoprotein
GPW86_RS15235	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPW86_RS15240	COG0792	nuclease activity
GPW86_RS15245	COG3107	peptidoglycan biosynthetic process
GPW86_RS15250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPW86_RS15265	COG0288	reversible hydration of carbon dioxide
GPW86_RS15270	COG0659	secondary active sulfate transmembrane transporter activity
GPW86_RS15275	COG1131	(ABC) transporter
GPW86_RS15280	COG0842	Transport permease protein
GPW86_RS15285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GPW86_RS15290	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GPW86_RS15295	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPW86_RS15305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPW86_RS15310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPW86_RS15315	COG1489	DNA binding
GPW86_RS15330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPW86_RS15335	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPW86_RS15340	COG1049	propionate catabolic process, 2-methylcitrate cycle
GPW86_RS15345	COG3112	Uncharacterised protein family (UPF0231)
GPW86_RS15350	COG0347	Belongs to the P(II) protein family
GPW86_RS15355	COG0004	ammonium transporteR
GPW86_RS15360	COG1840	ABC-type Fe3 transport system, periplasmic component
GPW86_RS15370	COG3842	ATPase activity
GPW86_RS15390	COG2971	BadF BadG BcrA BcrD
GPW86_RS15400	COG4608	Belongs to the ABC transporter superfamily
GPW86_RS15405	COG0444	Belongs to the ABC transporter superfamily
GPW86_RS15410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPW86_RS15420	COG0747	negative chemotaxis
GPW86_RS15430	COG2813	Specifically methylates the guanine in position
GPW86_RS15445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GPW86_RS15450	COG0316	Belongs to the HesB IscA family
GPW86_RS15465	COG0739	heme binding
GPW86_RS15470	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPW86_RS15475	COG2027	D-alanyl-D-alanine carboxypeptidase
GPW86_RS15480	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPW86_RS15485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPW86_RS15490	COG1534	Rna-binding protein
GPW86_RS15495	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GPW86_RS15500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPW86_RS15505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPW86_RS15510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPW86_RS15515	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPW86_RS15530	COG0779	Required for maturation of 30S ribosomal subunits
GPW86_RS15535	COG0195	Participates in both transcription termination and antitermination
GPW86_RS15540	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPW86_RS15545	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPW86_RS15550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPW86_RS15555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPW86_RS15560	COG1185	polyribonucleotide nucleotidyltransferase activity
GPW86_RS15565	COG4785	May be involved in cell division
GPW86_RS15600	COG3153	acetyltransferase
GPW86_RS15620	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GPW86_RS15625	COG0513	Belongs to the DEAD box helicase family
GPW86_RS15630	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GPW86_RS15645	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GPW86_RS15650	COG2204	response regulator
GPW86_RS15665	COG0667	Aldo Keto reductase
GPW86_RS15670	COG3066	DNA modification
GPW86_RS15675	COG0494	nUDIX hydrolase
GPW86_RS15680	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GPW86_RS15685	COG0730	response to heat
GPW86_RS15690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPW86_RS15695	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPW86_RS15700	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPW86_RS15705	COG0583	DNA-binding transcription factor activity
GPW86_RS15710	COG0640	Transcriptional regulator
GPW86_RS15715	COG0268	Binds directly to 16S ribosomal RNA
GPW86_RS15720	COG0728	peptidoglycan biosynthetic process
GPW86_RS15725	COG0196	riboflavin kinase activity
GPW86_RS15730	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPW86_RS15735	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPW86_RS15740	COG1047	Peptidyl-prolyl cis-trans
GPW86_RS15745	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GPW86_RS15750	COG1966	Carbon starvation protein
GPW86_RS15765	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPW86_RS15775	COG1472	Belongs to the glycosyl hydrolase 3 family
GPW86_RS15780	COG3279	Response regulator of the LytR AlgR family
GPW86_RS15785	COG3275	phosphorelay sensor kinase activity
GPW86_RS15790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPW86_RS15795	COG0287	Prephenate dehydrogenase
GPW86_RS15795	COG1605	Chorismate mutase
GPW86_RS15805	COG0488	(ABC) transporter
GPW86_RS15815	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GPW86_RS15820	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GPW86_RS15825	COG5001	Diguanylate cyclase
GPW86_RS15830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPW86_RS15835	COG0077	Prephenate dehydratase
GPW86_RS15835	COG1605	Chorismate mutase
GPW86_RS15840	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPW86_RS15845	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPW86_RS15850	COG0564	pseudouridine synthase activity
GPW86_RS15860	COG0542	response to heat
GPW86_RS15905	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPW86_RS15915	COG2974	May be involved in recombination
GPW86_RS15920	COG0745	RESPONSE REGULATOR receiver
GPW86_RS15925	COG5002	protein histidine kinase activity
GPW86_RS15935	COG0248	Ppx GppA phosphatase
GPW86_RS15940	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GPW86_RS15950	COG0581	inorganic phosphate transmembrane transporter activity
GPW86_RS15955	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPW86_RS15970	COG3142	Participates in the control of copper homeostasis
GPW86_RS15975	COG0450	alkyl hydroperoxide reductase
GPW86_RS15980	COG0583	DNA-binding transcription factor activity
GPW86_RS15985	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GPW86_RS15995	COG0517	IMP dehydrogenase activity
GPW86_RS16000	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPW86_RS16005	COG0343	queuine tRNA-ribosyltransferase activity
GPW86_RS16010	COG1862	Preprotein translocase
GPW86_RS16015	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPW86_RS16020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPW86_RS16025	COG0483	inositol monophosphate 1-phosphatase activity
GPW86_RS16035	COG1959	2 iron, 2 sulfur cluster binding
GPW86_RS16045	COG0822	iron-sulfur transferase activity
GPW86_RS16065	COG0633	Ferredoxin
GPW86_RS16070	COG2975	iron-sulfur cluster assembly
GPW86_RS16075	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPW86_RS16080	COG0105	UTP biosynthetic process
GPW86_RS16085	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GPW86_RS16090	COG1426	Protein conserved in bacteria
GPW86_RS16095	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GPW86_RS16100	COG0124	histidyl-tRNA synthetase
GPW86_RS16105	COG2976	Protein conserved in bacteria
GPW86_RS16110	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPW86_RS16130	COG1570	exodeoxyribonuclease VII activity
GPW86_RS16135	COG0517	IMP dehydrogenase activity
GPW86_RS16135	COG0516	GMP reductase activity
GPW86_RS16140	COG0519	Catalyzes the synthesis of GMP from XMP
GPW86_RS16140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GPW86_RS16150	COG3023	N-Acetylmuramoyl-L-alanine amidase
GPW86_RS16160	COG1584	GPR1 FUN34 yaaH family protein
GPW86_RS16165	COG3433	isochorismatase activity
GPW86_RS16165	COG1535	isochorismatase
GPW86_RS16170	COG1021	2,3-dihydroxybenzoate-AMP ligase
GPW86_RS16175	COG1169	isochorismate synthase
GPW86_RS16180	COG1028	Short-chain dehydrogenase reductase Sdr
GPW86_RS16190	COG4592	Periplasmic binding protein
GPW86_RS16195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPW86_RS16200	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPW86_RS16205	COG1120	ATPase activity
GPW86_RS16215	COG0583	DNA-binding transcription factor activity
GPW86_RS16225	COG1115	amino acid carrier protein
GPW86_RS16230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPW86_RS16250	COG4565	transcriptional regulatory protein
GPW86_RS16260	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPW86_RS16265	COG5016	pyruvate
GPW86_RS16265	COG0511	ligase activity, forming carbon-carbon bonds
GPW86_RS16270	COG3630	sodium ion export across plasma membrane
GPW86_RS16280	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GPW86_RS16285	COG3052	prosthetic group binding
GPW86_RS16290	COG2301	Belongs to the HpcH HpaI aldolase family
GPW86_RS16295	COG3051	citrate lyase alpha subunit
GPW86_RS16300	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
GPW86_RS16315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPW86_RS16320	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GPW86_RS16325	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GPW86_RS16340	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GPW86_RS16345	COG0732	type I restriction modification DNA specificity domain
GPW86_RS16350	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GPW86_RS16370	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GPW86_RS16375	COG2867	negative regulation of translational initiation
GPW86_RS16380	COG2914	Belongs to the UPF0125 (RnfH) family
GPW86_RS16385	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPW86_RS16390	COG0497	DNA recombination
GPW86_RS16395	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPW86_RS16400	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPW86_RS16405	COG0443	Heat shock 70 kDa protein
GPW86_RS16410	COG0484	heat shock protein binding
GPW86_RS16420	COG4968	Prepilin-type N-terminal cleavage methylation domain
GPW86_RS16450	COG0590	tRNA wobble adenosine to inosine editing
GPW86_RS16455	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GPW86_RS16465	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPW86_RS16465	COG0047	phosphoribosylformylglycinamidine synthase activity
GPW86_RS16485	COG0442	prolyl-tRNA aminoacylation
GPW86_RS16490	COG1720	tRNA m6t6A37 methyltransferase activity
GPW86_RS16495	COG0254	rRNA binding
GPW86_RS16500	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GPW86_RS16505	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPW86_RS16510	COG1671	Belongs to the UPF0178 family
GPW86_RS16520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPW86_RS16535	COG3098	single-species biofilm formation
GPW86_RS16540	COG0564	pseudouridine synthase activity
GPW86_RS16550	COG0142	geranyltranstransferase activity
GPW86_RS16555	COG1722	exodeoxyribonuclease VII activity
GPW86_RS16560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPW86_RS16570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPW86_RS16570	COG0301	tRNA thio-modification
GPW86_RS16575	COG0583	DNA-binding transcription factor activity
GPW86_RS16580	COG2363	Small membrane protein
GPW86_RS16585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPW86_RS16590	COG1611	Belongs to the LOG family
GPW86_RS16595	COG3706	GGDEF domain
GPW86_RS16605	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPW86_RS16605	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPW86_RS16615	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GPW86_RS16620	COG1464	Belongs to the NlpA lipoprotein family
GPW86_RS16625	COG2011	ABC-type metal ion transport system permease component
GPW86_RS16635	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPW86_RS16640	COG1609	Transcriptional regulator
GPW86_RS16645	COG1263	PTS System
GPW86_RS16645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPW86_RS16650	COG0366	Alpha amylase catalytic
GPW86_RS16680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPW86_RS16685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPW86_RS16690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GPW86_RS16695	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GPW86_RS16700	COG0110	maltose O-acetyltransferase activity
GPW86_RS16720	COG1045	serine acetyltransferase
GPW86_RS16730	COG0438	transferase activity, transferring glycosyl groups
GPW86_RS16740	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GPW86_RS16770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPW86_RS16780	COG1596	polysaccharide export
GPW86_RS16805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPW86_RS16815	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GPW86_RS16820	COG0321	lipoyl(octanoyl) transferase activity
GPW86_RS16825	COG2921	Belongs to the UPF0250 family
GPW86_RS16830	COG1686	Belongs to the peptidase S11 family
GPW86_RS16835	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPW86_RS16840	COG0772	Belongs to the SEDS family
GPW86_RS16845	COG0768	penicillin binding
GPW86_RS16850	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPW86_RS16855	COG0799	negative regulation of ribosome biogenesis
GPW86_RS16860	COG1466	dna polymerase III delta subunit
GPW86_RS16865	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GPW86_RS16870	COG0495	leucyl-tRNA aminoacylation
GPW86_RS16875	COG2888	peptidyl-tyrosine sulfation
GPW86_RS16880	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GPW86_RS16885	COG4535	Mg2 and Co2 transporter CorC
GPW86_RS16890	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPW86_RS16895	COG1702	phosphate starvation-inducible protein PhoH
GPW86_RS16900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPW86_RS16905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPW86_RS16910	COG2190	(PTS) system
GPW86_RS16920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPW86_RS16930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPW86_RS16935	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GPW86_RS16940	COG3115	cell septum assembly
GPW86_RS16945	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPW86_RS16960	COG0789	Transcriptional regulator
GPW86_RS16965	COG1585	Membrane protein implicated in regulation of membrane protease activity
GPW86_RS16970	COG0330	HflC and HflK could
GPW86_RS16975	COG3118	belongs to the thioredoxin family
GPW86_RS16985	COG0300	oxidoreductase activity
GPW86_RS16990	COG1090	epimerase
GPW86_RS16995	COG0622	Phosphoesterase
GPW86_RS17010	COG3710	Transcriptional regulator
GPW86_RS17015	COG0326	Molecular chaperone. Has ATPase activity
GPW86_RS17020	COG0563	adenylate kinase activity
GPW86_RS17025	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GPW86_RS17030	COG3104	oligopeptide transport
GPW86_RS17040	COG0367	asparagine synthase
GPW86_RS17045	COG4651	solute:proton antiporter activity
GPW86_RS17045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPW86_RS17050	COG1940	carbohydrate kinase activity
GPW86_RS17050	COG1846	Transcriptional regulator
GPW86_RS17055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPW86_RS17060	COG1263	PTS System
GPW86_RS17060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPW86_RS17060	COG2190	(PTS) system
GPW86_RS17065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPW86_RS17075	COG0101	tRNA pseudouridine synthase activity
GPW86_RS17080	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPW86_RS17085	COG0285	dihydrofolate synthase activity
GPW86_RS17090	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GPW86_RS17095	COG1286	toxin biosynthetic process
GPW86_RS17100	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPW86_RS17105	COG2056	Na+-H+ antiporter family
GPW86_RS17125	COG0346	lactoylglutathione lyase activity
GPW86_RS17130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPW86_RS17135	COG4660	Part of a membrane complex involved in electron transport
GPW86_RS17140	COG4659	FMN binding
GPW86_RS17145	COG4658	electron transport chain
GPW86_RS17150	COG4656	Part of a membrane complex involved in electron transport
GPW86_RS17155	COG2878	Part of a membrane complex involved in electron transport
GPW86_RS17160	COG4657	Part of a membrane complex involved in electron transport
GPW86_RS17170	COG0556	nucleotide-excision repair
GPW86_RS17175	COG2204	response regulator
GPW86_RS17180	COG2198	Histidine kinase
GPW86_RS17185	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GPW86_RS17190	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPW86_RS17195	COG0521	Mo-molybdopterin cofactor biosynthetic process
GPW86_RS17200	COG0315	cyclic pyranopterin monophosphate synthase activity
GPW86_RS17205	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPW86_RS17210	COG0314	molybdopterin synthase activity
GPW86_RS17215	COG2199	diguanylate cyclase activity
GPW86_RS17220	COG4109	DRTGG domain
GPW86_RS17230	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GPW86_RS17245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPW86_RS17245	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPW86_RS17250	COG0489	protein tyrosine kinase activity
GPW86_RS17255	COG0572	uridine kinase
GPW86_RS17260	COG2982	Protein involved in outer membrane biogenesis
GPW86_RS17265	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GPW86_RS17270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPW86_RS17275	COG2067	long-chain fatty acid transport protein
GPW86_RS17280	COG2067	long-chain fatty acid transport protein
GPW86_RS17295	COG0183	Belongs to the thiolase family
GPW86_RS17300	COG1024	Enoyl-CoA hydratase
GPW86_RS17300	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPW86_RS17305	COG0778	Nitroreductase
GPW86_RS17310	COG0583	DNA-binding transcription factor activity
GPW86_RS17315	COG0745	RESPONSE REGULATOR receiver
GPW86_RS17325	COG2832	Protein of unknown function (DUF454)
GPW86_RS17330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPW86_RS17335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPW86_RS17340	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPW86_RS17345	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPW86_RS17360	COG1028	Short-chain dehydrogenase reductase Sdr
GPW86_RS17365	COG0616	signal peptide processing
GPW86_RS17375	COG1522	sequence-specific DNA binding
GPW86_RS17380	COG1946	Acyl-CoA thioesterase
GPW86_RS17400	COG3706	GGDEF domain
GPW86_RS17440	COG0322	excinuclease ABC activity
GPW86_RS17495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPW86_RS17505	COG0640	Transcriptional regulator
GPW86_RS17510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPW86_RS17535	COG1881	PFAM PEBP family protein
GPW86_RS17555	COG0009	L-threonylcarbamoyladenylate synthase
GPW86_RS17570	COG2201	protein-glutamate methylesterase activity
GPW86_RS17580	COG5002	protein histidine kinase activity
GPW86_RS17585	COG4191	Histidine kinase
GPW86_RS17595	COG2204	response regulator
GPW86_RS17615	COG0601	transmembrane transport
GPW86_RS17620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPW86_RS17625	COG0444	Belongs to the ABC transporter superfamily
GPW86_RS17630	COG4608	Belongs to the ABC transporter superfamily
GPW86_RS17635	COG0435	Glutathione S-transferase
GPW86_RS17640	COG0857	belongs to the CobB CobQ family
GPW86_RS17640	COG0280	phosphate acetyltransferase
GPW86_RS17645	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPW86_RS17650	COG3092	negative regulation of chromosome organization
GPW86_RS17655	COG4628	conserved protein (DUF2132)
GPW86_RS17665	COG4120	Belongs to the binding-protein-dependent transport system permease family
GPW86_RS17675	COG3706	GGDEF domain
GPW86_RS17680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPW86_RS17685	COG0653	protein targeting
GPW86_RS17690	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GPW86_RS17695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GPW86_RS17700	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPW86_RS17705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GPW86_RS17710	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPW86_RS17715	COG0156	8-amino-7-oxononanoate synthase activity
GPW86_RS17720	COG2226	methyltransferase
GPW86_RS17725	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GPW86_RS17735	COG0501	Belongs to the peptidase M48B family
GPW86_RS17745	COG0300	oxidoreductase activity
GPW86_RS17760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GPW86_RS17770	COG2268	Band 7 protein
GPW86_RS17780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPW86_RS17785	COG2915	High frequency lysogenization protein hflD homolog
GPW86_RS17790	COG0482	sulfurtransferase activity
GPW86_RS17795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPW86_RS17800	COG2916	Histone family protein nucleoid-structuring protein H-NS
GPW86_RS17805	COG1757	Na H antiporter
GPW86_RS17810	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GPW86_RS17815	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPW86_RS17820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPW86_RS17825	COG0131	Imidazoleglycerol-phosphate dehydratase
GPW86_RS17825	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPW86_RS17830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPW86_RS17835	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPW86_RS17840	COG0107	imidazoleglycerol-phosphate synthase activity
GPW86_RS17845	COG0140	phosphoribosyl-ATP diphosphatase activity
GPW86_RS17845	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GPW86_RS17850	COG1187	pseudouridine synthase activity
GPW86_RS17860	COG1278	Cold shock
GPW86_RS17865	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GPW86_RS17870	COG0542	response to heat
GPW86_RS17880	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPW86_RS17885	COG1012	belongs to the aldehyde dehydrogenase family
GPW86_RS17885	COG1454	alcohol dehydrogenase
GPW86_RS17890	COG1737	Transcriptional regulator
GPW86_RS17895	COG0076	glutamate decarboxylase activity
GPW86_RS17905	COG2431	L-lysine efflux transmembrane transporter activity
GPW86_RS17915	COG3070	regulator of competence-specific genes
GPW86_RS17930	COG3852	Histidine kinase
GPW86_RS17940	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPW86_RS17955	COG0189	ligase activity
GPW86_RS17955	COG4067	protein conserved in archaea
GPW86_RS17960	COG0500	methyltransferase
GPW86_RS17965	COG4106	trans-aconitate 2-methyltransferase activity
GPW86_RS17975	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GPW86_RS17980	COG1435	thymidine kinase activity
GPW86_RS17990	COG0159	tryptophan synthase activity
GPW86_RS17995	COG0133	tryptophan synthase activity
GPW86_RS18000	COG0135	phosphoribosylanthranilate isomerase activity
GPW86_RS18000	COG0134	indole-3-glycerol-phosphate synthase activity
GPW86_RS18005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPW86_RS18010	COG0512	Glutamine amidotransferase of anthranilate synthase
GPW86_RS18015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPW86_RS18025	COG0613	PHP domain protein
GPW86_RS18030	COG0009	L-threonylcarbamoyladenylate synthase
GPW86_RS18035	COG1187	pseudouridine synthase activity
GPW86_RS18040	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GPW86_RS18050	COG0492	ferredoxin-NADP+ reductase activity
GPW86_RS18060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPW86_RS18065	COG3706	GGDEF domain
GPW86_RS18070	COG2949	membrane
GPW86_RS18080	COG0281	malic enzyme
GPW86_RS18090	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GPW86_RS18110	COG2885	chlorophyll binding
GPW86_RS18125	COG0277	FAD linked oxidase domain protein
GPW86_RS18125	COG0247	lactate metabolic process
GPW86_RS18145	COG2986	histidine ammonia-lyase
GPW86_RS18150	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GPW86_RS18155	COG0010	Belongs to the arginase family
GPW86_RS18160	COG1228	amidohydrolase
GPW86_RS18180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPW86_RS18190	COG5001	Diguanylate cyclase
GPW86_RS18195	COG0417	DNA replication proofreading
GPW86_RS18200	COG2197	response regulator
GPW86_RS18205	COG0322	excinuclease ABC activity
GPW86_RS18235	COG0745	RESPONSE REGULATOR receiver
GPW86_RS18235	COG3706	GGDEF domain
GPW86_RS18245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPW86_RS18250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPW86_RS18250	COG0072	phenylalanine-tRNA ligase activity
GPW86_RS18255	COG0776	regulation of translation
GPW86_RS18270	COG0500	methyltransferase
GPW86_RS18290	COG0295	cytidine deaminase activity
GPW86_RS18295	COG1346	cytolysis
GPW86_RS18305	COG2925	Exonuclease
GPW86_RS18315	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPW86_RS18320	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GPW86_RS18325	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GPW86_RS18340	COG2988	succinylglutamate desuccinylase activity
GPW86_RS18350	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GPW86_RS18395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPW86_RS18400	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPW86_RS18405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPW86_RS18425	COG2814	Major facilitator Superfamily
GPW86_RS18435	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPW86_RS18465	COG3108	Peptidase M15
GPW86_RS18470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPW86_RS18485	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPW86_RS18510	COG1846	Transcriptional regulator
GPW86_RS18515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPW86_RS18520	COG2943	transferase activity, transferring hexosyl groups
GPW86_RS18525	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GPW86_RS18530	COG0840	transmembrane signaling receptor activity
GPW86_RS18545	COG1448	Aminotransferase
GPW86_RS18555	COG3437	response regulator, receiver
GPW86_RS18555	COG2770	Histidine kinase
GPW86_RS18565	COG0017	Asparaginyl-tRNA synthetase
GPW86_RS18575	COG0720	synthase
GPW86_RS18580	COG1760	l-serine dehydratase
GPW86_RS18585	COG0814	amino acid
GPW86_RS18590	COG0494	nUDIX hydrolase
GPW86_RS18595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPW86_RS18610	COG3106	COG3106 Predicted ATPase
GPW86_RS18615	COG3768	UPF0283 membrane protein
GPW86_RS18620	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GPW86_RS18625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPW86_RS18640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPW86_RS18650	COG0471	metal ion transport
GPW86_RS18655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPW86_RS18655	COG4191	Histidine kinase
GPW86_RS18665	COG2990	Protein conserved in bacteria
GPW86_RS18670	COG3713	MltA-interacting MipA family protein
GPW86_RS18675	COG5002	protein histidine kinase activity
GPW86_RS18680	COG0745	RESPONSE REGULATOR receiver
GPW86_RS18705	COG1129	ABC transporter
GPW86_RS18725	COG1566	PFAM secretion protein HlyD family protein
GPW86_RS18755	COG0583	DNA-binding transcription factor activity
GPW86_RS18775	COG2186	Transcriptional regulator
GPW86_RS18780	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPW86_RS18785	COG0372	Belongs to the citrate synthase family
GPW86_RS18815	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPW86_RS18825	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GPW86_RS18835	COG0625	glutathione transferase activity
GPW86_RS18840	COG3437	response regulator, receiver
GPW86_RS18870	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPW86_RS18875	COG1254	Belongs to the acylphosphatase family
GPW86_RS18880	COG2920	part of a sulfur-relay system
GPW86_RS18885	COG0670	Belongs to the BI1 family
GPW86_RS18890	COG1126	abc transporter atp-binding protein
GPW86_RS18895	COG0765	amino acid transport
GPW86_RS18900	COG4597	amino acid ABC transporter
GPW86_RS18905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPW86_RS18915	COG0561	phosphatase activity
GPW86_RS18920	COG0602	queuosine metabolic process
GPW86_RS18925	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPW86_RS18955	COG3706	GGDEF domain
GPW86_RS18960	COG0443	Heat shock 70 kDa protein
GPW86_RS19000	COG1643	Atp-dependent helicase
GPW86_RS19010	COG0443	Heat shock 70 kDa protein
GPW86_RS19015	COG0095	Lipoate-protein ligase
GPW86_RS19020	COG0402	S-adenosylhomocysteine deaminase activity
GPW86_RS19030	COG0583	DNA-binding transcription factor activity
GPW86_RS19035	COG0477	Major facilitator Superfamily
GPW86_RS19040	COG0415	Belongs to the DNA photolyase family
GPW86_RS19045	COG2076	Multidrug Resistance protein
GPW86_RS19050	COG0513	Belongs to the DEAD box helicase family
GPW86_RS19070	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GPW86_RS19080	COG3501	Rhs element vgr protein
GPW86_RS19135	COG1280	lysine exporter protein (LysE YggA)
GPW86_RS19140	COG1115	amino acid carrier protein
GPW86_RS19155	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPW86_RS19160	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPW86_RS19165	COG1177	transmembrane transport
GPW86_RS19170	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPW86_RS19175	COG3842	ATPase activity
GPW86_RS19195	COG0037	tRNA processing
GPW86_RS19200	COG0589	response to stress
GPW86_RS19205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPW86_RS19220	COG2217	Heavy metal translocating P-type atpase
GPW86_RS19230	COG2010	Cytochrome c
GPW86_RS19245	COG3278	Belongs to the heme-copper respiratory oxidase family
GPW86_RS19260	COG2205	protein histidine kinase activity
GPW86_RS19260	COG0784	Response regulator, receiver
GPW86_RS19285	COG2994	toxin metabolic process
GPW86_RS19290	COG1073	alpha beta
GPW86_RS19290	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GPW86_RS19290	COG3064	Membrane