locus-tag	class	description
VCA1552_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VCA1552_RS00010	COG0592	DNA-directed DNA polymerase activity
VCA1552_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VCA1552_RS00020	COG0187	DNA topoisomerase II activity
VCA1552_RS00035	COG0071	Belongs to the small heat shock protein (HSP20) family
VCA1552_RS00040	COG3977	Valine--pyruvate aminotransferase
VCA1552_RS00050	COG0751	glycine-tRNA ligase activity
VCA1552_RS00055	COG0752	glycyl-tRNA synthetase alpha subunit
VCA1552_RS00060	COG2119	membrane
VCA1552_RS00075	COG0425	Belongs to the sulfur carrier protein TusA family
VCA1552_RS00085	COG0604	alcohol dehydrogenase
VCA1552_RS00095	COG0129	dihydroxy-acid dehydratase activity
VCA1552_RS00100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCA1552_RS00115	COG0606	chelatase, subunit chli
VCA1552_RS00120	COG0204	Acyl-transferase
VCA1552_RS00125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCA1552_RS00130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VCA1552_RS00145	COG3084	Protein conserved in bacteria
VCA1552_RS00155	COG4326	sporulation control protein
VCA1552_RS00160	COG1272	protein, Hemolysin III
VCA1552_RS00170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCA1552_RS00175	COG0569	domain protein
VCA1552_RS00180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCA1552_RS00180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VCA1552_RS00185	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VCA1552_RS00190	COG0242	peptide deformylase activity
VCA1552_RS00195	COG1652	LysM domain
VCA1552_RS00200	COG0758	DNA mediated transformation
VCA1552_RS00205	COG2922	Belongs to the Smg family
VCA1552_RS00210	COG0551	DNA topoisomerase type I activity
VCA1552_RS00215	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VCA1552_RS00220	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VCA1552_RS00225	COG0009	L-threonylcarbamoyladenylate synthase
VCA1552_RS00230	COG0408	coproporphyrinogen oxidase activity
VCA1552_RS00235	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VCA1552_RS00245	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VCA1552_RS00280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VCA1552_RS00290	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VCA1552_RS00300	COG1072	(Pantothenic acid kinase))
VCA1552_RS00325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCA1552_RS00330	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCA1552_RS00335	COG0250	Participates in transcription elongation, termination and antitermination
VCA1552_RS00340	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VCA1552_RS00350	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VCA1552_RS00355	COG0222	ribosome binding
VCA1552_RS00360	COG0085	RNA polymerase activity
VCA1552_RS00365	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VCA1552_RS00370	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VCA1552_RS00375	COG2816	NAD+ diphosphatase activity
VCA1552_RS00380	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VCA1552_RS00395	COG4942	peptidase
VCA1552_RS00400	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VCA1552_RS00410	COG0490	domain, Protein
VCA1552_RS00410	COG0471	metal ion transport
VCA1552_RS00415	COG0688	phosphatidylethanolamine metabolic process
VCA1552_RS00420	COG1162	GTPase activity
VCA1552_RS00425	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
VCA1552_RS00480	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VCA1552_RS00485	COG0802	atpase or kinase
VCA1552_RS00495	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
VCA1552_RS00500	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VCA1552_RS00505	COG1923	regulation of RNA biosynthetic process
VCA1552_RS00510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VCA1552_RS00515	COG0330	HflC and HflK could
VCA1552_RS00520	COG0330	HflC and HflK could
VCA1552_RS00525	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VCA1552_RS00530	COG2900	Belongs to the SlyX family
VCA1552_RS00540	COG0545	Peptidyl-prolyl cis-trans isomerase
VCA1552_RS00545	COG2964	Protein conserved in bacteria
VCA1552_RS00550	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
VCA1552_RS00555	COG2923	Belongs to the DsrF TusC family
VCA1552_RS00570	COG0049	tRNA binding
VCA1552_RS00575	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCA1552_RS00580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCA1552_RS00585	COG2906	2 iron, 2 sulfur cluster binding
VCA1552_RS00595	COG0360	Binds together with S18 to 16S ribosomal RNA
VCA1552_RS00600	COG2965	DNA replication, synthesis of RNA primer
VCA1552_RS00605	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VCA1552_RS00610	COG0359	binds to the 23S rRNA
VCA1552_RS00625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCA1552_RS00630	COG0432	Pfam Uncharacterised protein family UPF0047
VCA1552_RS00650	COG0735	belongs to the Fur family
VCA1552_RS00655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCA1552_RS00680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCA1552_RS00690	COG0175	sulfate reduction
VCA1552_RS00760	COG0646	methionine synthase
VCA1552_RS00760	COG1410	methionine synthase
VCA1552_RS00765	COG0527	aspartate kinase activity
VCA1552_RS00770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCA1552_RS00780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VCA1552_RS00795	COG0629	single-stranded DNA binding
VCA1552_RS00800	COG2200	EAL domain
VCA1552_RS00800	COG2199	diguanylate cyclase activity
VCA1552_RS00825	COG3409	Peptidoglycan-binding domain 1 protein
VCA1552_RS00825	COG3267	Type II secretory pathway component ExeA
VCA1552_RS00835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCA1552_RS00840	COG1459	type II secretion system
VCA1552_RS00850	COG2165	general secretion pathway protein
VCA1552_RS00855	COG2165	general secretion pathway protein
VCA1552_RS00885	COG1077	Cell shape determining protein MreB Mrl
VCA1552_RS00890	COG1792	Involved in formation and maintenance of cell shape
VCA1552_RS00895	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VCA1552_RS00900	COG0424	maF-like protein
VCA1552_RS00910	COG3164	Protein of unknown function
VCA1552_RS00915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VCA1552_RS00920	COG0312	modulator of DNA gyrase
VCA1552_RS00925	COG2235	arginine
VCA1552_RS00945	COG0589	response to stress
VCA1552_RS00955	COG2358	TRAP transporter, solute receptor (TAXI family
VCA1552_RS00965	COG1438	arginine binding
VCA1552_RS00970	COG0039	L-malate dehydrogenase activity
VCA1552_RS00975	COG0531	amino acid
VCA1552_RS00980	COG0142	geranyltranstransferase activity
VCA1552_RS00985	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VCA1552_RS00990	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VCA1552_RS00995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VCA1552_RS01000	COG2966	Psort location CytoplasmicMembrane, score
VCA1552_RS01005	COG3610	response to peptide
VCA1552_RS01015	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VCA1552_RS01020	COG2967	ApaG domain
VCA1552_RS01025	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VCA1552_RS01030	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VCA1552_RS01035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCA1552_RS01040	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
VCA1552_RS01045	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VCA1552_RS01100	COG0741	lytic transglycosylase activity
VCA1552_RS01105	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VCA1552_RS01110	COG1194	a g-specific adenine glycosylase
VCA1552_RS01120	COG2066	Belongs to the glutaminase family
VCA1552_RS01125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VCA1552_RS01130	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VCA1552_RS01140	COG1872	DUF167
VCA1552_RS01145	COG0762	integral membrane protein
VCA1552_RS01150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VCA1552_RS01155	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VCA1552_RS01175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCA1552_RS01180	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VCA1552_RS01185	COG1678	Uncharacterized ACR, COG1678
VCA1552_RS01190	COG0189	ligase activity
VCA1552_RS01195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VCA1552_RS01200	COG2356	endonuclease I
VCA1552_RS01210	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VCA1552_RS01215	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCA1552_RS01220	COG0583	DNA-binding transcription factor activity
VCA1552_RS01225	COG4771	TonB-dependent receptor
VCA1552_RS01230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCA1552_RS01235	COG0126	phosphoglycerate kinase activity
VCA1552_RS01240	COG0191	fructose-bisphosphate aldolase activity
VCA1552_RS01250	COG0668	transmembrane transport
VCA1552_RS01255	COG1279	arginine transmembrane transporter activity
VCA1552_RS01275	COG1349	DNA-binding transcription factor activity
VCA1552_RS01280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VCA1552_RS01285	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCA1552_RS01340	COG0328	RNA-DNA hybrid ribonuclease activity
VCA1552_RS01355	COG4969	Belongs to the N-Me-Phe pilin family
VCA1552_RS01365	COG0739	heme binding
VCA1552_RS01400	COG2003	Belongs to the UPF0758 family
VCA1552_RS01425	COG0582	viral genome integration into host DNA
VCA1552_RS01440	COG0358	DNA primase activity
VCA1552_RS01445	COG1610	YqeY-like protein
VCA1552_RS01450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VCA1552_RS01455	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
VCA1552_RS01465	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VCA1552_RS01475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VCA1552_RS01480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCA1552_RS01485	COG1968	undecaprenyl-diphosphatase activity
VCA1552_RS01490	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VCA1552_RS01495	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VCA1552_RS01500	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VCA1552_RS01505	COG0585	pseudouridine synthase activity
VCA1552_RS01510	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VCA1552_RS01515	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VCA1552_RS01525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCA1552_RS01530	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VCA1552_RS01550	COG4208	sulfate ABC transporter
VCA1552_RS01555	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
VCA1552_RS01565	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VCA1552_RS01575	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VCA1552_RS01580	COG0527	aspartate kinase activity
VCA1552_RS01585	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VCA1552_RS01630	COG3630	sodium ion export across plasma membrane
VCA1552_RS01635	COG5016	pyruvate
VCA1552_RS01635	COG0511	ligase activity, forming carbon-carbon bonds
VCA1552_RS01640	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCA1552_RS01650	COG1238	metal cluster binding
VCA1552_RS01655	COG0612	Peptidase, M16
VCA1552_RS01660	COG2918	glutathione biosynthetic process
VCA1552_RS01665	COG1854	S-ribosylhomocysteine lyase activity
VCA1552_RS01670	COG4536	flavin adenine dinucleotide binding
VCA1552_RS01675	COG4137	Cytochrome C assembly protein
VCA1552_RS01680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VCA1552_RS01685	COG0228	four-way junction DNA binding
VCA1552_RS01690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
VCA1552_RS01695	COG0336	Belongs to the RNA methyltransferase TrmD family
VCA1552_RS01700	COG0335	large ribosomal subunit rRNA binding
VCA1552_RS01705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCA1552_RS01710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCA1552_RS01720	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VCA1552_RS01725	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VCA1552_RS01730	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VCA1552_RS01735	COG0723	plastoquinol--plastocyanin reductase activity
VCA1552_RS01740	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VCA1552_RS01745	COG2857	Cytochrome c1
VCA1552_RS01750	COG0625	glutathione transferase activity
VCA1552_RS01755	COG2969	positive regulation of protein catabolic process
VCA1552_RS01760	COG2823	Periplasmic or secreted lipoprotein
VCA1552_RS01765	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCA1552_RS01770	COG0792	nuclease activity
VCA1552_RS01775	COG3107	peptidoglycan biosynthetic process
VCA1552_RS01780	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VCA1552_RS01800	COG0288	reversible hydration of carbon dioxide
VCA1552_RS01805	COG0659	secondary active sulfate transmembrane transporter activity
VCA1552_RS01810	COG1131	(ABC) transporter
VCA1552_RS01815	COG0842	Transport permease protein
VCA1552_RS01820	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VCA1552_RS01825	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VCA1552_RS01830	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCA1552_RS01840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCA1552_RS01850	COG1489	DNA binding
VCA1552_RS01860	COG1643	Atp-dependent helicase
VCA1552_RS01865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VCA1552_RS01870	COG1752	Esterase of the alpha-beta hydrolase superfamily
VCA1552_RS01875	COG1049	propionate catabolic process, 2-methylcitrate cycle
VCA1552_RS01880	COG3112	Uncharacterised protein family (UPF0231)
VCA1552_RS01885	COG0347	Belongs to the P(II) protein family
VCA1552_RS01890	COG0004	ammonium transporteR
VCA1552_RS01895	COG1840	ABC-type Fe3 transport system, periplasmic component
VCA1552_RS01905	COG3842	ATPase activity
VCA1552_RS01925	COG2971	BadF BadG BcrA BcrD
VCA1552_RS01935	COG4608	Belongs to the ABC transporter superfamily
VCA1552_RS01940	COG0444	Belongs to the ABC transporter superfamily
VCA1552_RS01945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCA1552_RS01950	COG0601	transmembrane transport
VCA1552_RS01955	COG0747	negative chemotaxis
VCA1552_RS01965	COG0784	Response regulator, receiver
VCA1552_RS01965	COG2205	protein histidine kinase activity
VCA1552_RS01970	COG2813	Specifically methylates the guanine in position
VCA1552_RS01975	COG0628	permease
VCA1552_RS01980	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VCA1552_RS01985	COG0316	Belongs to the HesB IscA family
VCA1552_RS02000	COG0739	heme binding
VCA1552_RS02005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCA1552_RS02010	COG2027	D-alanyl-D-alanine carboxypeptidase
VCA1552_RS02015	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCA1552_RS02020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCA1552_RS02025	COG1534	Rna-binding protein
VCA1552_RS02030	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VCA1552_RS02035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VCA1552_RS02040	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VCA1552_RS02055	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCA1552_RS02070	COG0779	Required for maturation of 30S ribosomal subunits
VCA1552_RS02075	COG0195	Participates in both transcription termination and antitermination
VCA1552_RS02080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
VCA1552_RS02085	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VCA1552_RS02095	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VCA1552_RS02120	COG0826	peptidase U32
VCA1552_RS02125	COG0826	peptidase U32
VCA1552_RS02135	COG3154	lipid carrier protein
VCA1552_RS02140	COG3153	acetyltransferase
VCA1552_RS02165	COG0513	Belongs to the DEAD box helicase family
VCA1552_RS02185	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VCA1552_RS02190	COG2204	response regulator
VCA1552_RS02200	COG0667	Aldo Keto reductase
VCA1552_RS02210	COG0494	nUDIX hydrolase
VCA1552_RS02215	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VCA1552_RS02220	COG0730	response to heat
VCA1552_RS02225	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VCA1552_RS02235	COG1283	sodium-dependent phosphate transmembrane transporter activity
VCA1552_RS02240	COG0583	DNA-binding transcription factor activity
VCA1552_RS02245	COG0640	Transcriptional regulator
VCA1552_RS02250	COG0268	Binds directly to 16S ribosomal RNA
VCA1552_RS02255	COG0728	peptidoglycan biosynthetic process
VCA1552_RS02260	COG0196	riboflavin kinase activity
VCA1552_RS02275	COG1047	Peptidyl-prolyl cis-trans
VCA1552_RS02280	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VCA1552_RS02285	COG1966	Carbon starvation protein
VCA1552_RS02300	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCA1552_RS02305	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VCA1552_RS02315	COG3279	Response regulator of the LytR AlgR family
VCA1552_RS02320	COG3275	phosphorelay sensor kinase activity
VCA1552_RS02325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCA1552_RS02330	COG0287	Prephenate dehydrogenase
VCA1552_RS02330	COG1605	Chorismate mutase
VCA1552_RS02340	COG0488	(ABC) transporter
VCA1552_RS02350	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VCA1552_RS02360	COG5001	Diguanylate cyclase
VCA1552_RS02365	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCA1552_RS02370	COG1605	Chorismate mutase
VCA1552_RS02370	COG0077	Prephenate dehydratase
VCA1552_RS02375	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCA1552_RS02380	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCA1552_RS02385	COG0564	pseudouridine synthase activity
VCA1552_RS02395	COG0542	response to heat
VCA1552_RS02435	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCA1552_RS02440	COG0826	peptidase U32
VCA1552_RS02450	COG0745	RESPONSE REGULATOR receiver
VCA1552_RS02455	COG5002	protein histidine kinase activity
VCA1552_RS02465	COG0248	Ppx GppA phosphatase
VCA1552_RS02470	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VCA1552_RS02480	COG0581	inorganic phosphate transmembrane transporter activity
VCA1552_RS02485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCA1552_RS02500	COG3142	Participates in the control of copper homeostasis
VCA1552_RS02505	COG0450	alkyl hydroperoxide reductase
VCA1552_RS02510	COG0583	DNA-binding transcription factor activity
VCA1552_RS02515	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
VCA1552_RS02525	COG0517	IMP dehydrogenase activity
VCA1552_RS02545	COG1862	Preprotein translocase
VCA1552_RS02550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCA1552_RS02555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCA1552_RS02560	COG0483	inositol monophosphate 1-phosphatase activity
VCA1552_RS02570	COG1959	2 iron, 2 sulfur cluster binding
VCA1552_RS02575	COG1104	cysteine desulfurase activity
VCA1552_RS02580	COG0822	iron-sulfur transferase activity
VCA1552_RS02590	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VCA1552_RS02595	COG0443	Heat shock 70 kDa protein
VCA1552_RS02600	COG0633	Ferredoxin
VCA1552_RS02605	COG2975	iron-sulfur cluster assembly
VCA1552_RS02610	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCA1552_RS02615	COG0105	UTP biosynthetic process
VCA1552_RS02620	COG0820	rRNA (adenine-C2-)-methyltransferase activity
VCA1552_RS02630	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VCA1552_RS02635	COG0124	histidyl-tRNA synthetase
VCA1552_RS02640	COG2976	Protein conserved in bacteria
VCA1552_RS02645	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCA1552_RS02650	COG1160	GTP binding
VCA1552_RS02665	COG1570	exodeoxyribonuclease VII activity
VCA1552_RS02670	COG0516	GMP reductase activity
VCA1552_RS02670	COG0517	IMP dehydrogenase activity
VCA1552_RS02675	COG0519	Catalyzes the synthesis of GMP from XMP
VCA1552_RS02675	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VCA1552_RS02685	COG1584	GPR1 FUN34 yaaH family protein
VCA1552_RS02690	COG1535	isochorismatase
VCA1552_RS02690	COG3433	isochorismatase activity
VCA1552_RS02695	COG1021	2,3-dihydroxybenzoate-AMP ligase
VCA1552_RS02700	COG1169	isochorismate synthase
VCA1552_RS02705	COG1028	Short-chain dehydrogenase reductase Sdr
VCA1552_RS02715	COG4592	Periplasmic binding protein
VCA1552_RS02720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCA1552_RS02725	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCA1552_RS02730	COG1120	ATPase activity
VCA1552_RS02740	COG0583	DNA-binding transcription factor activity
VCA1552_RS02745	COG2015	COG2015, Alkyl sulfatase and related hydrolases
VCA1552_RS02750	COG1115	amino acid carrier protein
VCA1552_RS02760	COG0583	DNA-binding transcription factor activity
VCA1552_RS02775	COG4565	transcriptional regulatory protein
VCA1552_RS02785	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCA1552_RS02790	COG0511	ligase activity, forming carbon-carbon bonds
VCA1552_RS02790	COG5016	pyruvate
VCA1552_RS02795	COG3630	sodium ion export across plasma membrane
VCA1552_RS02805	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
VCA1552_RS02815	COG2301	Belongs to the HpcH HpaI aldolase family
VCA1552_RS02820	COG3051	citrate lyase alpha subunit
VCA1552_RS02840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCA1552_RS02845	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VCA1552_RS02850	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VCA1552_RS02915	COG1012	belongs to the aldehyde dehydrogenase family
VCA1552_RS02935	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
VCA1552_RS02940	COG0840	transmembrane signaling receptor activity
VCA1552_RS02945	COG3710	Transcriptional regulator
VCA1552_RS02955	COG2165	general secretion pathway protein
VCA1552_RS02970	COG4796	Type ii and iii secretion system protein
VCA1552_RS02990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCA1552_RS02995	COG1459	type II secretion system
VCA1552_RS03005	COG2207	Transcriptional regulator
VCA1552_RS03010	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
VCA1552_RS03030	COG0739	heme binding
VCA1552_RS03040	COG3064	Membrane
VCA1552_RS03045	COG0582	viral genome integration into host DNA
VCA1552_RS03055	COG0582	viral genome integration into host DNA
VCA1552_RS03065	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VCA1552_RS03070	COG2867	negative regulation of translational initiation
VCA1552_RS03075	COG2914	Belongs to the UPF0125 (RnfH) family
VCA1552_RS03080	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCA1552_RS03085	COG0497	DNA recombination
VCA1552_RS03090	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VCA1552_RS03095	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VCA1552_RS03100	COG0443	Heat shock 70 kDa protein
VCA1552_RS03105	COG0484	heat shock protein binding
VCA1552_RS03115	COG4968	Prepilin-type N-terminal cleavage methylation domain
VCA1552_RS03140	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCA1552_RS03150	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VCA1552_RS03160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VCA1552_RS03160	COG0047	phosphoribosylformylglycinamidine synthase activity
VCA1552_RS03190	COG0442	prolyl-tRNA aminoacylation
VCA1552_RS03195	COG1720	tRNA m6t6A37 methyltransferase activity
VCA1552_RS03200	COG0254	rRNA binding
VCA1552_RS03205	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCA1552_RS03210	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCA1552_RS03215	COG1671	Belongs to the UPF0178 family
VCA1552_RS03225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCA1552_RS03240	COG3098	single-species biofilm formation
VCA1552_RS03245	COG0564	pseudouridine synthase activity
VCA1552_RS03250	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VCA1552_RS03255	COG0142	geranyltranstransferase activity
VCA1552_RS03260	COG1722	exodeoxyribonuclease VII activity
VCA1552_RS03265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VCA1552_RS03275	COG0301	tRNA thio-modification
VCA1552_RS03275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCA1552_RS03280	COG0583	DNA-binding transcription factor activity
VCA1552_RS03285	COG2363	Small membrane protein
VCA1552_RS03290	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCA1552_RS03295	COG1611	Belongs to the LOG family
VCA1552_RS03310	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCA1552_RS03310	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCA1552_RS03320	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VCA1552_RS03325	COG1464	Belongs to the NlpA lipoprotein family
VCA1552_RS03330	COG2011	ABC-type metal ion transport system permease component
VCA1552_RS03335	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VCA1552_RS03340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCA1552_RS03345	COG1609	Transcriptional regulator
VCA1552_RS03350	COG1263	PTS System
VCA1552_RS03350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCA1552_RS03355	COG0366	Alpha amylase catalytic
VCA1552_RS03385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCA1552_RS03390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VCA1552_RS03395	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VCA1552_RS03400	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VCA1552_RS03405	COG0110	maltose O-acetyltransferase activity
VCA1552_RS03425	COG1045	serine acetyltransferase
VCA1552_RS03435	COG0438	transferase activity, transferring glycosyl groups
VCA1552_RS03445	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
VCA1552_RS03475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCA1552_RS03485	COG1596	polysaccharide export
VCA1552_RS03510	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCA1552_RS03520	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VCA1552_RS03525	COG0321	lipoyl(octanoyl) transferase activity
VCA1552_RS03530	COG2921	Belongs to the UPF0250 family
VCA1552_RS03535	COG1686	Belongs to the peptidase S11 family
VCA1552_RS03540	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCA1552_RS03545	COG0772	Belongs to the SEDS family
VCA1552_RS03550	COG0768	penicillin binding
VCA1552_RS03555	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VCA1552_RS03560	COG0799	negative regulation of ribosome biogenesis
VCA1552_RS03565	COG1466	dna polymerase III delta subunit
VCA1552_RS03570	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VCA1552_RS03575	COG0495	leucyl-tRNA aminoacylation
VCA1552_RS03580	COG2888	peptidyl-tyrosine sulfation
VCA1552_RS03585	COG0815	Transfers the fatty acyl group on membrane lipoproteins
VCA1552_RS03590	COG4535	Mg2 and Co2 transporter CorC
VCA1552_RS03600	COG1702	phosphate starvation-inducible protein PhoH
VCA1552_RS03605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCA1552_RS03610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCA1552_RS03615	COG2190	(PTS) system
VCA1552_RS03625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCA1552_RS03635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VCA1552_RS03640	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VCA1552_RS03645	COG3115	cell septum assembly
VCA1552_RS03650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VCA1552_RS03670	COG0789	Transcriptional regulator
VCA1552_RS03675	COG1585	Membrane protein implicated in regulation of membrane protease activity
VCA1552_RS03680	COG0330	HflC and HflK could
VCA1552_RS03690	COG3118	belongs to the thioredoxin family
VCA1552_RS03700	COG0300	oxidoreductase activity
VCA1552_RS03705	COG1090	epimerase
VCA1552_RS03710	COG0622	Phosphoesterase
VCA1552_RS03725	COG3710	Transcriptional regulator
VCA1552_RS03730	COG0326	Molecular chaperone. Has ATPase activity
VCA1552_RS03735	COG0563	adenylate kinase activity
VCA1552_RS03740	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VCA1552_RS03755	COG0367	asparagine synthase
VCA1552_RS03760	COG4651	solute:proton antiporter activity
VCA1552_RS03760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCA1552_RS03765	COG1846	Transcriptional regulator
VCA1552_RS03765	COG1940	carbohydrate kinase activity
VCA1552_RS03770	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCA1552_RS03775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCA1552_RS03775	COG1263	PTS System
VCA1552_RS03775	COG2190	(PTS) system
VCA1552_RS03790	COG0101	tRNA pseudouridine synthase activity
VCA1552_RS03795	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VCA1552_RS03800	COG0285	dihydrofolate synthase activity
VCA1552_RS03805	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VCA1552_RS03810	COG1286	toxin biosynthetic process
VCA1552_RS03815	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VCA1552_RS03820	COG2056	Na+-H+ antiporter family
VCA1552_RS03825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCA1552_RS03840	COG0346	lactoylglutathione lyase activity
VCA1552_RS03845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VCA1552_RS03865	COG4656	Part of a membrane complex involved in electron transport
VCA1552_RS03870	COG2878	Part of a membrane complex involved in electron transport
VCA1552_RS03875	COG4657	Part of a membrane complex involved in electron transport
VCA1552_RS03885	COG0556	nucleotide-excision repair
VCA1552_RS03895	COG2204	response regulator
VCA1552_RS03900	COG2198	Histidine kinase
VCA1552_RS03905	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VCA1552_RS03910	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VCA1552_RS03915	COG0521	Mo-molybdopterin cofactor biosynthetic process
VCA1552_RS03920	COG0315	cyclic pyranopterin monophosphate synthase activity
VCA1552_RS03925	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VCA1552_RS03930	COG0314	molybdopterin synthase activity
VCA1552_RS03935	COG2199	diguanylate cyclase activity
VCA1552_RS03940	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
VCA1552_RS03940	COG0617	tRNA 3'-terminal CCA addition
VCA1552_RS03940	COG0517	IMP dehydrogenase activity
VCA1552_RS03955	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCA1552_RS03965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCA1552_RS03965	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCA1552_RS03970	COG0489	protein tyrosine kinase activity
VCA1552_RS03980	COG0572	uridine kinase
VCA1552_RS03985	COG2982	Protein involved in outer membrane biogenesis
VCA1552_RS03990	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VCA1552_RS03995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
VCA1552_RS04025	COG0183	Belongs to the thiolase family
VCA1552_RS04030	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCA1552_RS04030	COG1024	Enoyl-CoA hydratase
VCA1552_RS04035	COG0778	Nitroreductase
VCA1552_RS04040	COG0583	DNA-binding transcription factor activity
VCA1552_RS04045	COG0745	RESPONSE REGULATOR receiver
VCA1552_RS04055	COG2832	Protein of unknown function (DUF454)
VCA1552_RS04060	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VCA1552_RS04070	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VCA1552_RS04075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VCA1552_RS04085	COG2983	Belongs to the UPF0260 family
VCA1552_RS04090	COG1028	Short-chain dehydrogenase reductase Sdr
VCA1552_RS04095	COG0616	signal peptide processing
VCA1552_RS04105	COG1522	sequence-specific DNA binding
VCA1552_RS04110	COG1946	Acyl-CoA thioesterase
VCA1552_RS04130	COG3706	GGDEF domain
VCA1552_RS04140	COG0640	Transcriptional regulator
VCA1552_RS04145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCA1552_RS04170	COG1881	PFAM PEBP family protein
VCA1552_RS04190	COG0009	L-threonylcarbamoyladenylate synthase
VCA1552_RS04205	COG2201	protein-glutamate methylesterase activity
VCA1552_RS04215	COG5002	protein histidine kinase activity
VCA1552_RS04220	COG4191	Histidine kinase
VCA1552_RS04225	COG5001	Diguanylate cyclase
VCA1552_RS04225	COG3300	MHYT domain
VCA1552_RS04230	COG2204	response regulator
VCA1552_RS04250	COG0601	transmembrane transport
VCA1552_RS04255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCA1552_RS04260	COG0444	Belongs to the ABC transporter superfamily
VCA1552_RS04265	COG4608	Belongs to the ABC transporter superfamily
VCA1552_RS04270	COG0435	Glutathione S-transferase
VCA1552_RS04275	COG0280	phosphate acetyltransferase
VCA1552_RS04275	COG0857	belongs to the CobB CobQ family
VCA1552_RS04280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCA1552_RS04285	COG3092	negative regulation of chromosome organization
VCA1552_RS04290	COG4628	conserved protein (DUF2132)
VCA1552_RS04300	COG4120	Belongs to the binding-protein-dependent transport system permease family
VCA1552_RS04310	COG2199	diguanylate cyclase activity
VCA1552_RS04310	COG2203	Gaf domain
VCA1552_RS04315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCA1552_RS04325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VCA1552_RS04330	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VCA1552_RS04335	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VCA1552_RS04340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
VCA1552_RS04345	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCA1552_RS04350	COG0156	8-amino-7-oxononanoate synthase activity
VCA1552_RS04355	COG2226	methyltransferase
VCA1552_RS04360	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VCA1552_RS04370	COG0501	Belongs to the peptidase M48B family
VCA1552_RS04380	COG0300	oxidoreductase activity
VCA1552_RS04395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCA1552_RS04405	COG2268	Band 7 protein
VCA1552_RS04415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VCA1552_RS04420	COG2915	High frequency lysogenization protein hflD homolog
VCA1552_RS04425	COG0482	sulfurtransferase activity
VCA1552_RS04430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCA1552_RS04435	COG2916	Histone family protein nucleoid-structuring protein H-NS
VCA1552_RS04440	COG1757	Na H antiporter
VCA1552_RS04445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VCA1552_RS04450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VCA1552_RS04455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VCA1552_RS04460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCA1552_RS04460	COG0131	Imidazoleglycerol-phosphate dehydratase
VCA1552_RS04465	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VCA1552_RS04470	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VCA1552_RS04475	COG0107	imidazoleglycerol-phosphate synthase activity
VCA1552_RS04480	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VCA1552_RS04480	COG0140	phosphoribosyl-ATP diphosphatase activity
VCA1552_RS04485	COG1187	pseudouridine synthase activity
VCA1552_RS04495	COG1278	Cold shock
VCA1552_RS04500	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VCA1552_RS04505	COG0542	response to heat
VCA1552_RS04510	COG3273	potassium ion transport
VCA1552_RS04510	COG2985	domain, Protein
VCA1552_RS04515	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCA1552_RS04520	COG1012	belongs to the aldehyde dehydrogenase family
VCA1552_RS04520	COG1454	alcohol dehydrogenase
VCA1552_RS04525	COG1737	Transcriptional regulator
VCA1552_RS04530	COG0076	glutamate decarboxylase activity
VCA1552_RS04540	COG2431	L-lysine efflux transmembrane transporter activity
VCA1552_RS04550	COG3070	regulator of competence-specific genes
VCA1552_RS04565	COG3852	Histidine kinase
VCA1552_RS04575	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VCA1552_RS04590	COG4067	protein conserved in archaea
VCA1552_RS04590	COG0189	ligase activity
VCA1552_RS04595	COG0500	methyltransferase
VCA1552_RS04600	COG4106	trans-aconitate 2-methyltransferase activity
VCA1552_RS04605	COG1801	Protein of unknown function DUF72
VCA1552_RS04610	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VCA1552_RS04615	COG1435	thymidine kinase activity
VCA1552_RS04625	COG0159	tryptophan synthase activity
VCA1552_RS04630	COG0133	tryptophan synthase activity
VCA1552_RS04635	COG0134	indole-3-glycerol-phosphate synthase activity
VCA1552_RS04635	COG0135	phosphoribosylanthranilate isomerase activity
VCA1552_RS04640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
VCA1552_RS04645	COG0512	Glutamine amidotransferase of anthranilate synthase
VCA1552_RS04650	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCA1552_RS04660	COG0613	PHP domain protein
VCA1552_RS04665	COG0009	L-threonylcarbamoyladenylate synthase
VCA1552_RS04670	COG1187	pseudouridine synthase activity
VCA1552_RS04675	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VCA1552_RS04680	COG4988	ABC transporter
VCA1552_RS04685	COG0492	ferredoxin-NADP+ reductase activity
VCA1552_RS04695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCA1552_RS04700	COG3706	GGDEF domain
VCA1552_RS04705	COG2949	membrane
VCA1552_RS04715	COG0281	malic enzyme
VCA1552_RS04725	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
VCA1552_RS04745	COG2885	chlorophyll binding
VCA1552_RS04760	COG0277	FAD linked oxidase domain protein
VCA1552_RS04760	COG0247	lactate metabolic process
VCA1552_RS04780	COG2986	histidine ammonia-lyase
VCA1552_RS04785	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VCA1552_RS04790	COG0010	Belongs to the arginase family
VCA1552_RS04795	COG1228	amidohydrolase
VCA1552_RS04810	COG3099	Belongs to the UPF0263 family
VCA1552_RS04815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCA1552_RS04825	COG5001	Diguanylate cyclase
VCA1552_RS04830	COG0417	DNA replication proofreading
VCA1552_RS04835	COG2197	response regulator
VCA1552_RS04840	COG0322	excinuclease ABC activity
VCA1552_RS04880	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VCA1552_RS04885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCA1552_RS04885	COG0072	phenylalanine-tRNA ligase activity
VCA1552_RS04890	COG0776	regulation of translation
VCA1552_RS04930	COG1346	cytolysis
VCA1552_RS04935	COG1380	Effector of murein hydrolase LrgA
VCA1552_RS04940	COG2925	Exonuclease
VCA1552_RS04945	COG1823	symporter activity
VCA1552_RS04950	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCA1552_RS04960	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VCA1552_RS04965	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VCA1552_RS04985	COG4139	cobalamin transport
VCA1552_RS05040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCA1552_RS05045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCA1552_RS05050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCA1552_RS05060	COG1054	Belongs to the UPF0176 family
VCA1552_RS05070	COG2814	Major facilitator Superfamily
VCA1552_RS05080	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VCA1552_RS05105	COG2989	Protein conserved in bacteria
VCA1552_RS05110	COG3108	Peptidase M15
VCA1552_RS05115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCA1552_RS05130	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCA1552_RS05160	COG1846	Transcriptional regulator
VCA1552_RS05165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VCA1552_RS05170	COG0726	polysaccharide deacetylase
VCA1552_RS05175	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VCA1552_RS05185	COG1447	Phosphotransferase system cellobiose-specific component IIA
VCA1552_RS05190	COG1486	melibiose metabolic process
VCA1552_RS05200	COG1609	Transcriptional regulator
VCA1552_RS05205	COG2943	transferase activity, transferring hexosyl groups
VCA1552_RS05210	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
VCA1552_RS05215	COG0840	transmembrane signaling receptor activity
VCA1552_RS05230	COG1448	Aminotransferase
VCA1552_RS05245	COG0351	phosphomethylpyrimidine kinase
VCA1552_RS05250	COG0017	Asparaginyl-tRNA synthetase
VCA1552_RS05260	COG0720	synthase
VCA1552_RS05265	COG1760	l-serine dehydratase
VCA1552_RS05270	COG0814	amino acid
VCA1552_RS05275	COG0494	nUDIX hydrolase
VCA1552_RS05280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCA1552_RS05295	COG3106	COG3106 Predicted ATPase
VCA1552_RS05300	COG3768	UPF0283 membrane protein
VCA1552_RS05310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCA1552_RS05330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCA1552_RS05340	COG0471	metal ion transport
VCA1552_RS05345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCA1552_RS05345	COG4191	Histidine kinase
VCA1552_RS05355	COG2990	Protein conserved in bacteria
VCA1552_RS05360	COG3713	MltA-interacting MipA family protein
VCA1552_RS05365	COG2205	protein histidine kinase activity
VCA1552_RS05370	COG0745	RESPONSE REGULATOR receiver
VCA1552_RS05400	COG1129	ABC transporter
VCA1552_RS05440	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VCA1552_RS05445	COG0372	Belongs to the citrate synthase family
VCA1552_RS05485	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCA1552_RS05495	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
VCA1552_RS05505	COG0625	glutathione transferase activity
VCA1552_RS05510	COG3437	response regulator, receiver
VCA1552_RS05530	COG3706	GGDEF domain
VCA1552_RS05535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCA1552_RS05540	COG1254	Belongs to the acylphosphatase family
VCA1552_RS05545	COG2920	part of a sulfur-relay system
VCA1552_RS05550	COG0670	Belongs to the BI1 family
VCA1552_RS05555	COG1126	abc transporter atp-binding protein
VCA1552_RS05560	COG0765	amino acid transport
VCA1552_RS05565	COG4597	amino acid ABC transporter
VCA1552_RS05570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCA1552_RS05580	COG0561	phosphatase activity
VCA1552_RS05585	COG0602	queuosine metabolic process
VCA1552_RS05590	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VCA1552_RS05620	COG3706	GGDEF domain
VCA1552_RS05625	COG0443	Heat shock 70 kDa protein
VCA1552_RS05630	COG0443	Heat shock 70 kDa protein
VCA1552_RS05665	COG1643	Atp-dependent helicase
VCA1552_RS05675	COG0443	Heat shock 70 kDa protein
VCA1552_RS05680	COG0095	Lipoate-protein ligase
VCA1552_RS05690	COG0583	DNA-binding transcription factor activity
VCA1552_RS05695	COG0477	Major facilitator Superfamily
VCA1552_RS05700	COG0415	Belongs to the DNA photolyase family
VCA1552_RS05715	COG0745	RESPONSE REGULATOR receiver
VCA1552_RS05725	COG0643	Histidine kinase
VCA1552_RS05725	COG2198	Histidine kinase
VCA1552_RS05730	COG2198	Histidine kinase
VCA1552_RS05730	COG0784	Response regulator, receiver
VCA1552_RS05730	COG0643	Histidine kinase
VCA1552_RS05735	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCA1552_RS05745	COG2201	protein-glutamate methylesterase activity
VCA1552_RS05750	COG0835	chemotaxis
VCA1552_RS05755	COG0840	transmembrane signaling receptor activity
VCA1552_RS05755	COG3290	protein histidine kinase activity
VCA1552_RS05760	COG0840	transmembrane signaling receptor activity
VCA1552_RS05770	COG0513	Belongs to the DEAD box helicase family
VCA1552_RS05780	COG1538	Outer membrane efflux protein
VCA1552_RS05785	COG1566	PFAM secretion protein HlyD family protein
VCA1552_RS05790	COG2814	Major facilitator Superfamily
VCA1552_RS05800	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VCA1552_RS05810	COG3501	Rhs element vgr protein
VCA1552_RS05820	COG3675	Pfam Lipase (class 3)
VCA1552_RS05835	COG1280	lysine exporter protein (LysE YggA)
VCA1552_RS05840	COG1115	amino acid carrier protein
VCA1552_RS05855	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCA1552_RS05865	COG1177	transmembrane transport
VCA1552_RS05875	COG3842	ATPase activity
VCA1552_RS05900	COG0589	response to stress
VCA1552_RS05905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VCA1552_RS05920	COG2217	Heavy metal translocating P-type atpase
VCA1552_RS05930	COG2010	Cytochrome c
VCA1552_RS05945	COG3278	Belongs to the heme-copper respiratory oxidase family
VCA1552_RS05960	COG2205	protein histidine kinase activity
VCA1552_RS05960	COG0784	Response regulator, receiver
VCA1552_RS05985	COG2994	toxin metabolic process
VCA1552_RS05990	COG3064	Membrane
VCA1552_RS05990	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCA1552_RS05990	COG1073	alpha beta
VCA1552_RS06010	COG1476	TRANSCRIPTIONal
VCA1552_RS06030	COG4128	Pfam Zonular occludens toxin
VCA1552_RS06060	COG1476	TRANSCRIPTIONal
VCA1552_RS06155	COG3120	sequence-specific DNA binding
VCA1552_RS06160	COG1067	ATP-dependent peptidase activity
VCA1552_RS06165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCA1552_RS06180	COG0488	(ABC) transporter
VCA1552_RS06190	COG0116	Belongs to the methyltransferase superfamily
VCA1552_RS06190	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCA1552_RS06200	COG0167	dihydroorotate dehydrogenase activity
VCA1552_RS06215	COG0308	aminopeptidase N
VCA1552_RS06250	COG0641	radical SAM
VCA1552_RS06330	COG4695	Portal protein
VCA1552_RS06420	COG1428	Deoxynucleoside kinase
VCA1552_RS06490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
VCA1552_RS06495	COG0308	aminopeptidase N
VCA1552_RS06510	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VCA1552_RS06515	COG1956	GAF domain-containing protein
VCA1552_RS06520	COG1132	(ABC) transporter
VCA1552_RS06525	COG2995	paraquat-inducible protein a
VCA1552_RS06530	COG3008	intermembrane lipid transfer
VCA1552_RS06540	COG2996	Protein conserved in bacteria
VCA1552_RS06555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCA1552_RS06560	COG1666	GTP binding
VCA1552_RS06565	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VCA1552_RS06580	COG0437	4 iron, 4 sulfur cluster binding
VCA1552_RS06585	COG3383	formate dehydrogenase (NAD+) activity
VCA1552_RS06585	COG0243	molybdopterin cofactor binding
VCA1552_RS06615	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VCA1552_RS06620	COG0488	(ABC) transporter
VCA1552_RS06625	COG3852	Histidine kinase
VCA1552_RS06630	COG2204	response regulator
VCA1552_RS06640	COG4662	Binding-protein-dependent transport system inner membrane component
VCA1552_RS06645	COG3842	ATPase activity
VCA1552_RS06650	COG0746	molybdenum cofactor guanylyltransferase activity
VCA1552_RS06685	COG1940	carbohydrate kinase activity
VCA1552_RS06690	COG3148	PFAM DTW domain containing protein
VCA1552_RS06700	COG0840	transmembrane signaling receptor activity
VCA1552_RS06705	COG0791	NLP P60 protein
VCA1552_RS06715	COG3001	Fructosamine kinase
VCA1552_RS06725	COG0534	Mate efflux family protein
VCA1552_RS06735	COG1793	dna ligase
VCA1552_RS06750	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCA1552_RS06755	COG0848	biopolymer transport protein
VCA1552_RS06760	COG0811	peptide transport
VCA1552_RS06765	COG0811	peptide transport
VCA1552_RS06780	COG1175	transmembrane transport
VCA1552_RS06785	COG0395	ABC-type sugar transport system, permease component
VCA1552_RS06790	COG3842	ATPase activity
VCA1552_RS06795	COG1349	DNA-binding transcription factor activity
VCA1552_RS06800	COG0584	glycerophosphoryl diester phosphodiesterase
VCA1552_RS06805	COG2731	YhcH YjgK YiaL family protein
VCA1552_RS06810	COG0251	oxidation-reduction process
VCA1552_RS06815	COG1609	Transcriptional regulator
VCA1552_RS06820	COG2723	6-phospho-beta-galactosidase activity
VCA1552_RS06830	COG0583	DNA-binding transcription factor activity
VCA1552_RS06850	COG0577	efflux transmembrane transporter activity
VCA1552_RS06850	COG1136	(ABC) transporter
VCA1552_RS06855	COG1136	(ABC) transporter
VCA1552_RS06855	COG0577	efflux transmembrane transporter activity
VCA1552_RS06860	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCA1552_RS06860	COG1136	(ABC) transporter
VCA1552_RS06865	COG1294	oxidase, subunit
VCA1552_RS06870	COG1271	oxidase subunit
VCA1552_RS06915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCA1552_RS06925	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCA1552_RS06945	COG0753	catalase activity
VCA1552_RS06960	COG3527	Alpha-acetolactate decarboxylase
VCA1552_RS06975	COG2200	EAL domain
VCA1552_RS06975	COG2199	diguanylate cyclase activity
VCA1552_RS06985	COG2017	converts alpha-aldose to the beta-anomer
VCA1552_RS06990	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VCA1552_RS06995	COG1085	galactose-1-phosphate uridylyltransferase
VCA1552_RS07040	COG0835	chemotaxis
VCA1552_RS07040	COG0784	Response regulator, receiver
VCA1552_RS07050	COG4565	transcriptional regulatory protein
VCA1552_RS07055	COG3290	protein histidine kinase activity
VCA1552_RS07070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCA1552_RS07090	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VCA1552_RS07095	COG3063	Type IV pilus biogenesis stability protein PilW
VCA1552_RS07110	COG1451	nucleotide metabolic process
VCA1552_RS07120	COG0583	DNA-binding transcription factor activity
VCA1552_RS07140	COG1538	Outer membrane efflux protein
VCA1552_RS07155	COG1748	Saccharopine dehydrogenase
VCA1552_RS07170	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCA1552_RS07180	COG0577	efflux transmembrane transporter activity
VCA1552_RS07185	COG4181	ATPase activity
VCA1552_RS07190	COG0534	Mate efflux family protein
VCA1552_RS07195	COG0702	epimerase
VCA1552_RS07205	COG2814	Major facilitator Superfamily
VCA1552_RS07210	COG1187	pseudouridine synthase activity
VCA1552_RS07215	COG1061	Type III restriction enzyme res subunit
VCA1552_RS07235	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VCA1552_RS07240	COG3706	GGDEF domain
VCA1552_RS07240	COG5001	Diguanylate cyclase
VCA1552_RS07240	COG4251	negative regulation of phosphorylation
VCA1552_RS07240	COG2203	Gaf domain
VCA1552_RS07255	COG0840	transmembrane signaling receptor activity
VCA1552_RS07285	COG4934	collagen metabolic process
VCA1552_RS07300	COG0784	Response regulator, receiver
VCA1552_RS07300	COG2205	protein histidine kinase activity
VCA1552_RS07305	COG2239	Acts as a magnesium transporter
VCA1552_RS07315	COG0814	amino acid
VCA1552_RS07320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCA1552_RS07325	COG1131	(ABC) transporter
VCA1552_RS07330	COG0842	Transport permease protein
VCA1552_RS07340	COG3313	Fe-S protein
VCA1552_RS07350	COG4134	Bacterial extracellular solute-binding protein
VCA1552_RS07355	COG4135	transport system, permease component
VCA1552_RS07360	COG4136	ATPase activity
VCA1552_RS07365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VCA1552_RS07370	COG0564	pseudouridine synthase activity
VCA1552_RS07375	COG0733	neurotransmitter:sodium symporter activity
VCA1552_RS07390	COG0626	cystathionine gamma-synthase activity
VCA1552_RS07395	COG2818	Glycosylase
VCA1552_RS07410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCA1552_RS07425	COG1842	Phage shock protein A
VCA1552_RS07430	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VCA1552_RS07440	COG4168	peptide transport system, permease
VCA1552_RS07455	COG4172	Belongs to the ABC transporter superfamily
VCA1552_RS07470	COG1227	inorganic diphosphatase activity
VCA1552_RS07495	COG0243	molybdopterin cofactor binding
VCA1552_RS07500	COG3005	denitrification pathway
VCA1552_RS07505	COG4459	periplasmic nitrate reductase
VCA1552_RS07515	COG2116	formate transmembrane transporter activity
VCA1552_RS07530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCA1552_RS07535	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCA1552_RS07550	COG1607	acyl-coa hydrolase
VCA1552_RS07555	COG2350	Protein conserved in bacteria
VCA1552_RS07565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VCA1552_RS07570	COG0583	DNA-binding transcription factor activity
VCA1552_RS07585	COG0612	Peptidase, M16
VCA1552_RS07590	COG5001	Diguanylate cyclase
VCA1552_RS07595	COG1032	radical SAM domain protein
VCA1552_RS07615	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VCA1552_RS07625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCA1552_RS07630	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCA1552_RS07635	COG0745	RESPONSE REGULATOR receiver
VCA1552_RS07640	COG3381	protein complex oligomerization
VCA1552_RS07650	COG1609	Transcriptional regulator
VCA1552_RS07655	COG3070	regulator of competence-specific genes
VCA1552_RS07675	COG0297	glycogen (starch) synthase activity
VCA1552_RS07680	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCA1552_RS07685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCA1552_RS07715	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VCA1552_RS07725	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCA1552_RS07750	COG1012	belongs to the aldehyde dehydrogenase family
VCA1552_RS07755	COG1309	transcriptional regulator
VCA1552_RS07780	COG0668	transmembrane transport
VCA1552_RS07785	COG2995	paraquat-inducible protein a
VCA1552_RS07790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCA1552_RS07790	COG3008	intermembrane lipid transfer
VCA1552_RS07800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCA1552_RS07815	COG0582	viral genome integration into host DNA
VCA1552_RS07820	COG0582	viral genome integration into host DNA
VCA1552_RS07825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
VCA1552_RS07845	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
VCA1552_RS07865	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
VCA1552_RS07885	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VCA1552_RS07890	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VCA1552_RS07895	COG1737	Transcriptional regulator
VCA1552_RS07900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VCA1552_RS07905	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCA1552_RS07910	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCA1552_RS07915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCA1552_RS07930	COG1940	carbohydrate kinase activity
VCA1552_RS07935	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCA1552_RS07940	COG4409	exo-alpha-(2->6)-sialidase activity
VCA1552_RS07950	COG2003	Belongs to the UPF0758 family
VCA1552_RS07965	COG3941	tape measure
VCA1552_RS08010	COG0488	(ABC) transporter
VCA1552_RS08090	COG0415	Belongs to the DNA photolyase family
VCA1552_RS08100	COG4628	conserved protein (DUF2132)
VCA1552_RS08105	COG3284	Transcriptional regulator
VCA1552_RS08110	COG1012	belongs to the aldehyde dehydrogenase family
VCA1552_RS08120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCA1552_RS08125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCA1552_RS08130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCA1552_RS08140	COG2207	Transcriptional regulator
VCA1552_RS08145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCA1552_RS08145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCA1552_RS08145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCA1552_RS08150	COG1482	cell wall glycoprotein biosynthetic process
VCA1552_RS08160	COG0784	Response regulator, receiver
VCA1552_RS08160	COG5002	protein histidine kinase activity
VCA1552_RS08170	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VCA1552_RS08180	COG2885	chlorophyll binding
VCA1552_RS08185	COG0823	Involved in the tonB-independent uptake of proteins
VCA1552_RS08200	COG0811	peptide transport
VCA1552_RS08205	COG0824	Thioesterase
VCA1552_RS08210	COG3790	cyd operon protein YbgE
VCA1552_RS08215	COG4890	Cyd operon protein YbgT
VCA1552_RS08220	COG1294	oxidase, subunit
VCA1552_RS08225	COG1271	oxidase subunit
VCA1552_RS08235	COG0632	four-way junction helicase activity
VCA1552_RS08240	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VCA1552_RS08245	COG0215	cysteine-tRNA ligase activity
VCA1552_RS08250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCA1552_RS08255	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCA1552_RS08260	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCA1552_RS08265	COG3012	SEC-C Motif Domain Protein
VCA1552_RS08270	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCA1552_RS08275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCA1552_RS08280	COG1199	ATP-dependent helicase activity
VCA1552_RS08285	COG0730	response to heat
VCA1552_RS08290	COG3923	Primosomal replication protein n
VCA1552_RS08300	COG0840	transmembrane signaling receptor activity
VCA1552_RS08305	COG0708	Exodeoxyribonuclease III
VCA1552_RS08310	COG4160	amino acid transport
VCA1552_RS08340	COG1882	Formate acetyltransferase
VCA1552_RS08350	COG0840	transmembrane signaling receptor activity
VCA1552_RS08355	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VCA1552_RS08365	COG3013	Belongs to the UPF0304 family
VCA1552_RS08370	COG2766	serine protein kinase
VCA1552_RS08375	COG2718	Belongs to the UPF0229 family
VCA1552_RS08380	COG2719	SpoVR family
VCA1552_RS08385	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VCA1552_RS08390	COG2835	tetraacyldisaccharide 4'-kinase activity
VCA1552_RS08395	COG1663	tetraacyldisaccharide 4'-kinase activity
VCA1552_RS08400	COG1132	(ABC) transporter
VCA1552_RS08405	COG0658	competence protein
VCA1552_RS08405	COG2333	competence protein COMEC
VCA1552_RS08415	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCA1552_RS08420	COG1136	(ABC) transporter
VCA1552_RS08425	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCA1552_RS08435	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
VCA1552_RS08455	COG1252	NADH dehydrogenase
VCA1552_RS08460	COG3150	esterase
VCA1552_RS08485	COG0537	adenosine 5'-monophosphoramidase activity
VCA1552_RS08500	COG2186	Transcriptional regulator
VCA1552_RS08505	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCA1552_RS08510	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VCA1552_RS08515	COG1674	ftsk spoiiie
VCA1552_RS08525	COG0686	Belongs to the AlaDH PNT family
VCA1552_RS08535	COG0583	DNA-binding transcription factor activity
VCA1552_RS08555	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VCA1552_RS08560	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VCA1552_RS08565	COG0776	regulation of translation
VCA1552_RS08570	COG0539	negative regulation of cytoplasmic translation
VCA1552_RS08575	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VCA1552_RS08580	COG1555	photosystem II stabilization
VCA1552_RS08585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCA1552_RS08590	COG0776	regulation of translation
VCA1552_RS08595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
VCA1552_RS08600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VCA1552_RS08610	COG0544	peptidyl-prolyl cis-trans isomerase activity
VCA1552_RS08620	COG4191	Histidine kinase
VCA1552_RS08630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCA1552_RS08635	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCA1552_RS08640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCA1552_RS08645	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VCA1552_RS08660	COG3300	MHYT domain
VCA1552_RS08660	COG5001	Diguanylate cyclase
VCA1552_RS08670	COG4589	Belongs to the CDS family
VCA1552_RS08710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VCA1552_RS08720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCA1552_RS08740	COG0243	molybdopterin cofactor binding
VCA1552_RS08745	COG3005	denitrification pathway
VCA1552_RS08750	COG3325	Belongs to the glycosyl hydrolase 18 family
VCA1552_RS08750	COG3469	chitinase activity
VCA1552_RS08755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCA1552_RS08765	COG2951	lytic endotransglycosylase activity
VCA1552_RS08770	COG3100	YcgL domain-containing protein
VCA1552_RS08775	COG0850	regulation of cytokinetic process
VCA1552_RS08780	COG2894	cell division
VCA1552_RS08785	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VCA1552_RS08790	COG3015	lipoprotein NlpE involved in copper resistance
VCA1552_RS08810	COG0477	Major facilitator Superfamily
VCA1552_RS08815	COG0840	transmembrane signaling receptor activity
VCA1552_RS08820	COG1396	sequence-specific DNA binding
VCA1552_RS08825	COG3135	benzoate transporter
VCA1552_RS08845	COG0596	Alpha beta hydrolase
VCA1552_RS08850	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VCA1552_RS08855	COG1169	isochorismate synthase
VCA1552_RS08860	COG0436	Aminotransferase
VCA1552_RS08865	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VCA1552_RS08870	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VCA1552_RS08890	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VCA1552_RS08895	COG0318	PFAM AMP-dependent synthetase and ligase
VCA1552_RS08900	COG0596	Alpha beta hydrolase
VCA1552_RS08915	COG1214	PFAM Peptidase M22, glycoprotease
VCA1552_RS08920	COG1199	ATP-dependent helicase activity
VCA1552_RS08935	COG0788	formyltetrahydrofolate deformylase activity
VCA1552_RS08940	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCA1552_RS08940	COG1902	pentaerythritol trinitrate reductase activity
VCA1552_RS08945	COG0616	signal peptide processing
VCA1552_RS08950	COG0252	asparaginase activity
VCA1552_RS08955	COG3139	Protein of unknown function (DUF1315)
VCA1552_RS08965	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCA1552_RS08970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCA1552_RS08975	COG0676	glucose-6-phosphate 1-epimerase activity
VCA1552_RS08995	COG2226	methyltransferase
VCA1552_RS09010	COG0784	Response regulator, receiver
VCA1552_RS09010	COG0835	chemotaxis
VCA1552_RS09015	COG1940	carbohydrate kinase activity
VCA1552_RS09025	COG4667	esterase of the alpha-beta hydrolase superfamily
VCA1552_RS09040	COG0733	neurotransmitter:sodium symporter activity
VCA1552_RS09050	COG1263	PTS System
VCA1552_RS09050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCA1552_RS09055	COG0084	hydrolase, TatD family'
VCA1552_RS09065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VCA1552_RS09070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VCA1552_RS09075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCA1552_RS09080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCA1552_RS09085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VCA1552_RS09090	COG1028	Short-chain dehydrogenase reductase Sdr
VCA1552_RS09100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCA1552_RS09105	COG0416	fatty acid biosynthetic process
VCA1552_RS09110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VCA1552_RS09115	COG1399	metal-binding, possibly nucleic acid-binding protein
VCA1552_RS09120	COG0424	maF-like protein
VCA1552_RS09125	COG0564	pseudouridine synthase activity
VCA1552_RS09140	COG1530	ribonuclease E activity
VCA1552_RS09145	COG0659	secondary active sulfate transmembrane transporter activity
VCA1552_RS09160	COG1454	alcohol dehydrogenase
VCA1552_RS09160	COG1012	belongs to the aldehyde dehydrogenase family
VCA1552_RS09165	COG2095	MarC family integral membrane protein
VCA1552_RS09170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCA1552_RS09175	COG1757	Na H antiporter
VCA1552_RS09185	COG3081	Nucleoid-associated protein
VCA1552_RS09190	COG3082	Protein of unknown function (DUF1414)
VCA1552_RS09195	COG3083	sulfuric ester hydrolase activity
VCA1552_RS09210	COG0123	including yeast histone deacetylase and acetoin utilization protein
VCA1552_RS09215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCA1552_RS09220	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VCA1552_RS09240	COG2853	Lipoprotein
VCA1552_RS09250	COG3088	subunit of a heme lyase
VCA1552_RS09250	COG4235	cytochrome complex assembly
VCA1552_RS09255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VCA1552_RS09260	COG1138	Cytochrome C-type biogenesis protein
VCA1552_RS09265	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VCA1552_RS09275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCA1552_RS09280	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCA1552_RS09285	COG4133	protoheme IX ABC transporter activity
VCA1552_RS09295	COG0835	chemotaxis
VCA1552_RS09305	COG1192	Involved in chromosome partitioning
VCA1552_RS09310	COG2201	protein-glutamate methylesterase activity
VCA1552_RS09315	COG2198	Histidine kinase
VCA1552_RS09315	COG0643	Histidine kinase
VCA1552_RS09315	COG0784	Response regulator, receiver
VCA1552_RS09320	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VCA1552_RS09350	COG2062	phosphohistidine phosphatase, SixA
VCA1552_RS09355	COG1025	Belongs to the peptidase M16 family
VCA1552_RS09365	COG0018	arginyl-trna synthetase
VCA1552_RS09385	COG1918	ferrous iron import across plasma membrane
VCA1552_RS09390	COG4977	sequence-specific DNA binding
VCA1552_RS09395	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VCA1552_RS09400	COG1121	(ABC) transporter
VCA1552_RS09405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VCA1552_RS09415	COG0045	succinate-CoA ligase (ADP-forming) activity
VCA1552_RS09420	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCA1552_RS09425	COG0567	Dehydrogenase, E1 component
VCA1552_RS09435	COG1053	succinate dehydrogenase
VCA1552_RS09440	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VCA1552_RS09445	COG2009	succinate dehydrogenase
VCA1552_RS09450	COG0372	Belongs to the citrate synthase family
VCA1552_RS09455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VCA1552_RS09465	COG0033	Phosphoglucomutase
VCA1552_RS09470	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VCA1552_RS09475	COG0596	Alpha beta hydrolase
VCA1552_RS09490	COG1346	cytolysis
VCA1552_RS09500	COG0583	DNA-binding transcription factor activity
VCA1552_RS09510	COG0735	belongs to the Fur family
VCA1552_RS09515	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCA1552_RS09520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCA1552_RS09525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCA1552_RS09535	COG0431	NADPH-dependent FMN reductase
VCA1552_RS09545	COG3101	peptidyl-lysine hydroxylation
VCA1552_RS09550	COG2860	membrane
VCA1552_RS09555	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VCA1552_RS09565	COG2890	protein-(glutamine-N5) methyltransferase activity
VCA1552_RS09570	COG2840	Smr protein MutS2
VCA1552_RS09580	COG1684	flagellar biosynthetic protein fliR
VCA1552_RS09585	COG1987	bacterial-type flagellum assembly
VCA1552_RS09610	COG1580	Controls the rotational direction of flagella during chemotaxis
VCA1552_RS09635	COG1317	bacterial-type flagellum organization
VCA1552_RS09640	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VCA1552_RS09650	COG1677	Flagellar hook-basal body complex protein FliE
VCA1552_RS09670	COG1516	flagellar protein fliS
VCA1552_RS09680	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VCA1552_RS09685	COG1334	flagellar protein FlaG
VCA1552_RS09690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCA1552_RS09695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCA1552_RS09700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCA1552_RS09705	COG2837	iron assimilation
VCA1552_RS09725	COG1393	Belongs to the ArsC family
VCA1552_RS09735	COG1876	peptidase activity
VCA1552_RS09745	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VCA1552_RS09760	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VCA1552_RS09780	COG4783	chaperone-mediated protein folding
VCA1552_RS09785	COG1393	Belongs to the ArsC family
VCA1552_RS09805	COG2233	PERMEase
VCA1552_RS09810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VCA1552_RS09815	COG0737	Belongs to the 5'-nucleotidase family
VCA1552_RS09820	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VCA1552_RS09825	COG2912	Transglutaminase-like superfamily
VCA1552_RS09835	COG2890	protein-(glutamine-N5) methyltransferase activity
VCA1552_RS09840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VCA1552_RS09845	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VCA1552_RS09850	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VCA1552_RS09860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VCA1552_RS09865	COG0193	aminoacyl-tRNA hydrolase activity
VCA1552_RS09870	COG0012	GTP binding
VCA1552_RS09955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCA1552_RS09960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCA1552_RS09975	COG3951	Flagellar rod assembly protein muramidase FlgJ
VCA1552_RS09975	COG1705	Flagellar rod assembly protein muramidase FlgJ
VCA1552_RS09980	COG1706	bacterial-type flagellum-dependent cell motility
VCA1552_RS09985	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VCA1552_RS09995	COG4787	bacterial-type flagellum-dependent cell motility
VCA1552_RS10000	COG1749	Flagellar hook protein flgE
VCA1552_RS10015	COG1815	bacterial-type flagellum-dependent cell motility
VCA1552_RS10020	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCA1552_RS10025	COG0784	Response regulator, receiver
VCA1552_RS10025	COG0835	chemotaxis
VCA1552_RS10060	COG3433	isochorismatase activity
VCA1552_RS10060	COG2226	methyltransferase
VCA1552_RS10060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCA1552_RS10065	COG2375	cellular response to nickel ion
VCA1552_RS10070	COG1629	transport
VCA1552_RS10070	COG4774	siderophore transport
VCA1552_RS10085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCA1552_RS10090	COG2217	Heavy metal translocating P-type atpase
VCA1552_RS10090	COG2608	mercury ion transmembrane transporter activity
VCA1552_RS10105	COG3735	TraB family
VCA1552_RS10120	COG2840	Smr protein MutS2
VCA1552_RS10125	COG1187	pseudouridine synthase activity
VCA1552_RS10135	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VCA1552_RS10140	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VCA1552_RS10145	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VCA1552_RS10150	COG0121	glutamine amidotransferase
VCA1552_RS10155	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCA1552_RS10160	COG1960	acyl-CoA dehydrogenase activity
VCA1552_RS10175	COG0328	RNA-DNA hybrid ribonuclease activity
VCA1552_RS10180	COG2226	methyltransferase
VCA1552_RS10185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCA1552_RS10190	COG0741	lytic transglycosylase activity
VCA1552_RS10190	COG1388	LysM domain
VCA1552_RS10195	COG3021	interspecies interaction between organisms
VCA1552_RS10200	COG0347	Belongs to the P(II) protein family
VCA1552_RS10205	COG3479	Phenolic acid decarboxylase
VCA1552_RS10215	COG0037	tRNA processing
VCA1552_RS10220	COG0825	malonyl-CoA metabolic process
VCA1552_RS10225	COG0587	DNA-directed DNA polymerase activity
VCA1552_RS10230	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
VCA1552_RS10235	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCA1552_RS10240	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCA1552_RS10245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCA1552_RS10250	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCA1552_RS10255	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VCA1552_RS10265	COG0750	zinc metalloprotease
VCA1552_RS10270	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VCA1552_RS10275	COG0575	Belongs to the CDS family
VCA1552_RS10280	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VCA1552_RS10285	COG0233	cytoplasmic translational termination
VCA1552_RS10290	COG0528	UMP kinase activity
VCA1552_RS10295	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VCA1552_RS10300	COG0052	Belongs to the universal ribosomal protein uS2 family
VCA1552_RS10305	COG0024	Methionine aminopeptidase
VCA1552_RS10310	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VCA1552_RS10325	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VCA1552_RS10330	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VCA1552_RS10335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCA1552_RS10340	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VCA1552_RS10355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCA1552_RS10355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCA1552_RS10360	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VCA1552_RS10365	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VCA1552_RS10370	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VCA1552_RS10380	COG1073	alpha beta
VCA1552_RS10385	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VCA1552_RS10390	COG2252	PERMEase
VCA1552_RS10395	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCA1552_RS10400	COG4067	protein conserved in archaea
VCA1552_RS10400	COG0189	ligase activity
VCA1552_RS10405	COG0189	ligase activity
VCA1552_RS10415	COG0733	neurotransmitter:sodium symporter activity
VCA1552_RS10420	COG3706	GGDEF domain
VCA1552_RS10440	COG1477	protein flavinylation
VCA1552_RS10445	COG2871	sodium ion transport
VCA1552_RS10450	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCA1552_RS10455	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCA1552_RS10460	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCA1552_RS10465	COG1805	sodium ion transport
VCA1552_RS10470	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCA1552_RS10475	COG0271	Belongs to the BolA IbaG family
VCA1552_RS10480	COG2813	Specifically methylates the guanine in position
VCA1552_RS10490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCA1552_RS10500	COG2211	Major facilitator Superfamily
VCA1552_RS10510	COG1595	DNA-templated transcription, initiation
VCA1552_RS10520	COG3248	Nucleoside-binding outer membrane protein
VCA1552_RS10525	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VCA1552_RS10530	COG0693	protein deglycase activity
VCA1552_RS10535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCA1552_RS10540	COG2166	iron-sulfur cluster assembly
VCA1552_RS10545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VCA1552_RS10550	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VCA1552_RS10560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VCA1552_RS10560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCA1552_RS10570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VCA1552_RS10575	COG1074	ATP-dependent DNA helicase activity
VCA1552_RS10580	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VCA1552_RS10595	COG3141	response to X-ray
VCA1552_RS10600	COG2171	N-acyltransferase activity
VCA1552_RS10610	COG0456	acetyltransferase
VCA1552_RS10615	COG0569	domain protein
VCA1552_RS10615	COG0189	ligase activity
VCA1552_RS10630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCA1552_RS10635	COG1609	Transcriptional regulator
VCA1552_RS10640	COG3250	beta-galactosidase activity
VCA1552_RS10655	COG1022	Amp-dependent synthetase and ligase
VCA1552_RS10660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCA1552_RS10665	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VCA1552_RS10680	COG0560	Phosphoserine phosphatase
VCA1552_RS10690	COG0813	purine-nucleoside phosphorylase activity
VCA1552_RS10695	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VCA1552_RS10700	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VCA1552_RS10705	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VCA1552_RS10715	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCA1552_RS10720	COG0084	hydrolase, TatD family'
VCA1552_RS10725	COG3022	response to hydroperoxide
VCA1552_RS10730	COG1115	amino acid carrier protein
VCA1552_RS10745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VCA1552_RS10750	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VCA1552_RS10755	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VCA1552_RS10760	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
VCA1552_RS10785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCA1552_RS10795	COG0745	RESPONSE REGULATOR receiver
VCA1552_RS10800	COG2198	Histidine kinase
VCA1552_RS10800	COG0784	Response regulator, receiver
VCA1552_RS10800	COG5002	protein histidine kinase activity
VCA1552_RS10805	COG5001	Diguanylate cyclase
VCA1552_RS10805	COG3706	GGDEF domain
VCA1552_RS10805	COG2203	Gaf domain
VCA1552_RS10805	COG4251	negative regulation of phosphorylation
VCA1552_RS10810	COG1242	4 iron, 4 sulfur cluster binding
VCA1552_RS10815	COG0070	glutamate synthase
VCA1552_RS10815	COG0069	glutamate synthase activity
VCA1552_RS10815	COG0067	glutamate synthase
VCA1552_RS10825	COG0069	glutamate synthase activity
VCA1552_RS10825	COG0070	glutamate synthase
VCA1552_RS10825	COG0067	glutamate synthase
VCA1552_RS10830	COG0493	'glutamate synthase
VCA1552_RS10840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VCA1552_RS10850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VCA1552_RS10855	COG2860	membrane
VCA1552_RS10860	COG0583	DNA-binding transcription factor activity
VCA1552_RS10865	COG0730	response to heat
VCA1552_RS10875	COG4172	Belongs to the ABC transporter superfamily
VCA1552_RS10895	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VCA1552_RS10900	COG0505	Belongs to the CarA family
VCA1552_RS10910	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VCA1552_RS10915	COG0494	nUDIX hydrolase
VCA1552_RS10920	COG0653	protein targeting
VCA1552_RS10930	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VCA1552_RS10935	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VCA1552_RS10940	COG0849	cell division
VCA1552_RS10945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VCA1552_RS10950	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCA1552_RS10960	COG0772	Belongs to the SEDS family
VCA1552_RS10965	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VCA1552_RS10975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VCA1552_RS10980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VCA1552_RS10985	COG0768	penicillin binding
VCA1552_RS10990	COG3116	cell division
VCA1552_RS11005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCA1552_RS11010	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCA1552_RS11015	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VCA1552_RS11020	COG2186	Transcriptional regulator
VCA1552_RS11030	COG0737	Belongs to the 5'-nucleotidase family
VCA1552_RS11035	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VCA1552_RS11040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCA1552_RS11045	COG4974	Belongs to the 'phage' integrase family
VCA1552_RS11050	COG0716	FMN binding
VCA1552_RS11070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCA1552_RS11075	COG1459	type II secretion system
VCA1552_RS11085	COG0237	dephospho-CoA kinase activity
VCA1552_RS11090	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VCA1552_RS11100	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VCA1552_RS11105	COG0187	DNA topoisomerase II activity
VCA1552_RS11110	COG3150	esterase
VCA1552_RS11120	COG3151	Protein conserved in bacteria
VCA1552_RS11125	COG0494	nUDIX hydrolase
VCA1552_RS11130	COG1538	Outer membrane efflux protein
VCA1552_RS11140	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VCA1552_RS11145	COG0840	transmembrane signaling receptor activity
VCA1552_RS11150	COG3025	triphosphatase activity
VCA1552_RS11155	COG1392	Phosphate transport regulator
VCA1552_RS11160	COG0306	phosphate transporter
VCA1552_RS11165	COG4991	sh3 domain protein
VCA1552_RS11175	COG3267	Type II secretory pathway component ExeA
VCA1552_RS11175	COG3409	Peptidoglycan-binding domain 1 protein
VCA1552_RS11185	COG0148	phosphopyruvate hydratase activity
VCA1552_RS11190	COG0504	CTP synthase activity
VCA1552_RS11195	COG3956	TIGRFAM MazG family protein
VCA1552_RS11200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCA1552_RS11215	COG5001	Diguanylate cyclase
VCA1552_RS11235	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VCA1552_RS11240	COG1381	Involved in DNA repair and RecF pathway recombination
VCA1552_RS11245	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VCA1552_RS11260	COG0481	GTPase activity
VCA1552_RS11265	COG3086	response to oxidative stress
VCA1552_RS11280	COG1595	DNA-templated transcription, initiation
VCA1552_RS11290	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VCA1552_RS11300	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VCA1552_RS11315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCA1552_RS11320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCA1552_RS11325	COG3079	Belongs to the UPF0149 family
VCA1552_RS11330	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VCA1552_RS11340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VCA1552_RS11345	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VCA1552_RS11350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCA1552_RS11355	COG0440	acetolactate synthase activity
VCA1552_RS11360	COG0028	Belongs to the TPP enzyme family
VCA1552_RS11365	COG1022	Amp-dependent synthetase and ligase
VCA1552_RS11370	COG0583	DNA-binding transcription factor activity
VCA1552_RS11395	COG0473	3-isopropylmalate dehydrogenase activity
VCA1552_RS11400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VCA1552_RS11405	COG0066	3-isopropylmalate dehydratase activity
VCA1552_RS11450	COG3437	response regulator, receiver
VCA1552_RS11465	COG0795	lipopolysaccharide-transporting ATPase activity
VCA1552_RS11470	COG0795	lipopolysaccharide-transporting ATPase activity
VCA1552_RS11475	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCA1552_RS11480	COG2927	DNA polymerase III (CHI subunit)
VCA1552_RS11485	COG0525	valine-tRNA ligase activity
VCA1552_RS11490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCA1552_RS11495	COG0564	pseudouridine synthase activity
VCA1552_RS11510	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
VCA1552_RS11520	COG0540	Belongs to the ATCase OTCase family
VCA1552_RS11530	COG0251	oxidation-reduction process
VCA1552_RS11540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VCA1552_RS11545	COG5007	Belongs to the BolA IbaG family
VCA1552_RS11555	COG2854	intermembrane phospholipid transfer
VCA1552_RS11560	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCA1552_RS11565	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VCA1552_RS11570	COG1127	ABC transporter
VCA1552_RS11585	COG0517	IMP dehydrogenase activity
VCA1552_RS11585	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VCA1552_RS11600	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VCA1552_RS11605	COG1137	ATPase activity
VCA1552_RS11615	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCA1552_RS11620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCA1552_RS11625	COG1660	Displays ATPase and GTPase activities
VCA1552_RS11630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCA1552_RS11635	COG2239	Acts as a magnesium transporter
VCA1552_RS11640	COG0312	modulator of DNA gyrase
VCA1552_RS11645	COG3028	Belongs to the UPF0307 family
VCA1552_RS11650	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VCA1552_RS11655	COG1178	ABC-type Fe3 transport system permease component
VCA1552_RS11665	COG0163	prenyltransferase activity
VCA1552_RS11670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCA1552_RS11685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VCA1552_RS11690	COG2105	PFAM AIG2 family protein
VCA1552_RS11700	COG0729	surface antigen
VCA1552_RS11705	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCA1552_RS11710	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VCA1552_RS11725	COG1136	(ABC) transporter
VCA1552_RS11745	COG0529	Catalyzes the synthesis of activated sulfate
VCA1552_RS11760	COG1648	precorrin-2 dehydrogenase activity
VCA1552_RS11760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VCA1552_RS11765	COG0737	Belongs to the 5'-nucleotidase family
VCA1552_RS11775	COG0513	Belongs to the DEAD box helicase family
VCA1552_RS11780	COG2153	protein acetylation
VCA1552_RS11785	COG0697	spore germination
VCA1552_RS11790	COG3266	domain, Protein
VCA1552_RS11790	COG3061	Opacity-associated protein A
VCA1552_RS11795	COG0545	Peptidyl-prolyl cis-trans isomerase
VCA1552_RS11805	COG0203	ribosomal protein L17
VCA1552_RS11810	COG0202	RNA polymerase activity
VCA1552_RS11815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VCA1552_RS11820	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VCA1552_RS11825	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VCA1552_RS11830	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCA1552_RS11835	COG0201	protein transport
VCA1552_RS11845	COG1841	ribosomal large subunit assembly
VCA1552_RS11850	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VCA1552_RS11855	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VCA1552_RS11865	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VCA1552_RS11870	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VCA1552_RS11875	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VCA1552_RS11880	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VCA1552_RS11885	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VCA1552_RS11890	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VCA1552_RS11895	COG0255	Belongs to the universal ribosomal protein uL29 family
VCA1552_RS11900	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VCA1552_RS11905	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VCA1552_RS11910	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VCA1552_RS11915	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VCA1552_RS11920	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VCA1552_RS11925	COG0089	rRNA binding
VCA1552_RS11930	COG0088	Forms part of the polypeptide exit tunnel
VCA1552_RS11935	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VCA1552_RS11940	COG0051	transcription antitermination factor activity, RNA binding
VCA1552_RS11945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCA1552_RS11950	COG0557	exoribonuclease II activity
VCA1552_RS11955	COG3083	sulfuric ester hydrolase activity
VCA1552_RS11960	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VCA1552_RS11980	COG1047	Peptidyl-prolyl cis-trans
VCA1552_RS11995	COG2249	NAD(P)H dehydrogenase (quinone) activity
VCA1552_RS12000	COG0488	(ABC) transporter
VCA1552_RS12010	COG0429	hydrolase of the alpha beta-hydrolase fold
VCA1552_RS12020	COG3954	Phosphoribulokinase
VCA1552_RS12035	COG1012	belongs to the aldehyde dehydrogenase family
VCA1552_RS12045	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VCA1552_RS12055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCA1552_RS12070	COG0180	Tryptophanyl-tRNA synthetase
VCA1552_RS12075	COG0546	phosphoglycolate phosphatase activity
VCA1552_RS12080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VCA1552_RS12085	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VCA1552_RS12095	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VCA1552_RS12100	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VCA1552_RS12130	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
VCA1552_RS12140	COG0678	peroxiredoxin activity
VCA1552_RS12140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCA1552_RS12145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCA1552_RS12155	COG0165	Argininosuccinate lyase
VCA1552_RS12165	COG0137	argininosuccinate synthase activity
VCA1552_RS12170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCA1552_RS12175	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VCA1552_RS12180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VCA1552_RS12185	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VCA1552_RS12195	COG1045	serine acetyltransferase
VCA1552_RS12200	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VCA1552_RS12205	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VCA1552_RS12210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCA1552_RS12215	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VCA1552_RS12220	COG1053	succinate dehydrogenase
VCA1552_RS12225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VCA1552_RS12230	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VCA1552_RS12240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCA1552_RS12245	COG1509	lysine 2,3-aminomutase activity
VCA1552_RS12255	COG0459	protein refolding
VCA1552_RS12260	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCA1552_RS12290	COG0149	triose-phosphate isomerase activity
VCA1552_RS12295	COG0534	Mate efflux family protein
VCA1552_RS12300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCA1552_RS12305	COG1575	Belongs to the MenA family. Type 1 subfamily
VCA1552_RS12310	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VCA1552_RS12315	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VCA1552_RS12320	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCA1552_RS12325	COG1609	Transcriptional regulator
VCA1552_RS12330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VCA1552_RS12335	COG0254	rRNA binding
VCA1552_RS12340	COG0281	malic enzyme
VCA1552_RS12345	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VCA1552_RS12350	COG0626	cystathionine gamma-synthase activity
VCA1552_RS12355	COG0527	aspartate kinase activity
VCA1552_RS12355	COG0460	homoserine dehydrogenase
VCA1552_RS12360	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VCA1552_RS12365	COG3074	FtsZ-dependent cytokinesis
VCA1552_RS12370	COG1494	fructose-1,6-bisphosphatase
VCA1552_RS12375	COG0205	6-phosphofructokinase activity
VCA1552_RS12380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VCA1552_RS12390	COG0745	RESPONSE REGULATOR receiver
VCA1552_RS12395	COG2205	protein histidine kinase activity
VCA1552_RS12405	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VCA1552_RS12410	COG3030	protein affecting phage T7 exclusion by the F plasmid
VCA1552_RS12415	COG3706	GGDEF domain
VCA1552_RS12420	COG1027	Aspartate ammonia-lyase
VCA1552_RS12425	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCA1552_RS12435	COG4232	protein-disulfide reductase activity
VCA1552_RS12455	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCA1552_RS12460	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VCA1552_RS12465	COG0194	GDP metabolic process
VCA1552_RS12470	COG1758	RNA polymerase activity
VCA1552_RS12475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCA1552_RS12480	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VCA1552_RS12485	COG2233	PERMEase
VCA1552_RS12500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCA1552_RS12505	COG2183	response to ionizing radiation
VCA1552_RS12515	COG0596	Alpha beta hydrolase
VCA1552_RS12520	COG1040	competence protein
VCA1552_RS12530	COG0494	nUDIX hydrolase
VCA1552_RS12535	COG1218	3'(2'),5'-bisphosphate nucleotidase
VCA1552_RS12545	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCA1552_RS12550	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCA1552_RS12555	COG3156	type II secretion system protein K
VCA1552_RS12560	COG4795	General secretion pathway protein
VCA1552_RS12565	COG2165	general secretion pathway protein
VCA1552_RS12570	COG2165	general secretion pathway protein
VCA1552_RS12575	COG2165	general secretion pathway protein
VCA1552_RS12580	COG1459	type II secretion system
VCA1552_RS12585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCA1552_RS12595	COG3031	protein transport across the cell outer membrane
VCA1552_RS12600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VCA1552_RS12605	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VCA1552_RS12610	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VCA1552_RS12620	COG0456	acetyltransferase
VCA1552_RS12625	COG1490	D-aminoacyl-tRNA deacylase activity
VCA1552_RS12630	COG1295	ribonuclease BN
VCA1552_RS12635	COG1660	Displays ATPase and GTPase activities
VCA1552_RS12640	COG1217	gtp-binding protein TYPA
VCA1552_RS12650	COG0174	glutamine synthetase
VCA1552_RS12660	COG3852	Histidine kinase
VCA1552_RS12670	COG3300	MHYT domain
VCA1552_RS12670	COG5001	Diguanylate cyclase
VCA1552_RS12675	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VCA1552_RS12745	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VCA1552_RS12750	COG1404	Belongs to the peptidase S8 family
VCA1552_RS12755	COG4206	TonB-dependent receptor
VCA1552_RS12760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCA1552_RS12780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCA1552_RS12785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCA1552_RS12790	COG2177	Part of the ABC transporter FtsEX involved in
VCA1552_RS12795	COG2884	Cell division ATP-binding protein ftsE
VCA1552_RS12800	COG0552	protein localization to endoplasmic reticulum
VCA1552_RS12805	COG0742	ribosomal rna small subunit methyltransferase
VCA1552_RS12845	COG0783	Belongs to the Dps family
VCA1552_RS12850	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCA1552_RS12855	COG1280	lysine exporter protein (LysE YggA)
VCA1552_RS12860	COG2267	carboxylic ester hydrolase activity
VCA1552_RS12865	COG0561	phosphatase activity
VCA1552_RS12885	COG2200	EAL domain
VCA1552_RS12885	COG2199	diguanylate cyclase activity
VCA1552_RS12885	COG3287	FIST C domain
VCA1552_RS12890	COG1011	Hydrolase
VCA1552_RS12895	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VCA1552_RS12905	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VCA1552_RS12910	COG0019	diaminopimelate decarboxylase activity
VCA1552_RS12920	COG1965	Belongs to the frataxin family
VCA1552_RS12935	COG0181	hydroxymethylbilane synthase activity
VCA1552_RS12940	COG1587	Uroporphyrinogen-III synthase
VCA1552_RS12945	COG2959	enzyme of heme biosynthesis
VCA1552_RS12950	COG3071	HemY protein
VCA1552_RS12965	COG3078	GTPase activator activity
VCA1552_RS12985	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCA1552_RS12985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCA1552_RS13000	COG0084	hydrolase, TatD family'
VCA1552_RS13010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCA1552_RS13020	COG0840	transmembrane signaling receptor activity
VCA1552_RS13025	COG1580	Controls the rotational direction of flagella during chemotaxis
VCA1552_RS13035	COG3161	chorismate lyase activity
VCA1552_RS13040	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VCA1552_RS13055	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VCA1552_RS13065	COG0534	Mate efflux family protein
VCA1552_RS13070	COG1858	cytochrome C peroxidase
VCA1552_RS13075	COG0805	protein transport
VCA1552_RS13080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCA1552_RS13085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCA1552_RS13100	COG2226	methyltransferase
VCA1552_RS13105	COG1322	Protein conserved in bacteria
VCA1552_RS13115	COG2081	HI0933 family
VCA1552_RS13125	COG1528	Iron-storage protein
VCA1552_RS13135	COG0589	response to stress
VCA1552_RS13155	COG5001	Diguanylate cyclase
VCA1552_RS13155	COG5002	protein histidine kinase activity
VCA1552_RS13160	COG1522	sequence-specific DNA binding
VCA1552_RS13180	COG0006	proline dipeptidase activity
VCA1552_RS13180	COG0006	proline dipeptidase activity
VCA1552_RS13185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCA1552_RS13190	COG2022	thiamine diphosphate biosynthetic process
VCA1552_RS13195	COG2104	thiamine diphosphate biosynthetic process
VCA1552_RS13200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCA1552_RS13210	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VCA1552_RS13215	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VCA1552_RS13265	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VCA1552_RS13280	COG3118	belongs to the thioredoxin family
VCA1552_RS13285	COG0513	Belongs to the DEAD box helicase family
VCA1552_RS13290	COG0248	Ppx GppA phosphatase
VCA1552_RS13295	COG2205	protein histidine kinase activity
VCA1552_RS13295	COG0784	Response regulator, receiver
VCA1552_RS13300	COG2814	Major facilitator Superfamily
VCA1552_RS13320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCA1552_RS13325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VCA1552_RS13330	COG0511	ligase activity, forming carbon-carbon bonds
VCA1552_RS13335	COG0439	Biotin carboxylase
VCA1552_RS13340	COG2264	protein methyltransferase activity
VCA1552_RS13345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCA1552_RS13350	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VCA1552_RS13355	COG1609	Transcriptional regulator
VCA1552_RS13360	COG0129	dihydroxy-acid dehydratase activity
VCA1552_RS13365	COG3265	gluconokinase activity
VCA1552_RS13375	COG0800	Aldolase
VCA1552_RS13395	COG0840	transmembrane signaling receptor activity
VCA1552_RS13400	COG1982	Orn Lys Arg decarboxylase major
VCA1552_RS13405	COG0531	amino acid
VCA1552_RS13415	COG0789	Transcriptional regulator
VCA1552_RS13430	COG0151	Belongs to the GarS family
VCA1552_RS13440	COG0776	regulation of translation
VCA1552_RS13445	COG1253	flavin adenine dinucleotide binding
VCA1552_RS13450	COG1940	carbohydrate kinase activity
VCA1552_RS13460	COG3068	Protein conserved in bacteria
VCA1552_RS13470	COG1573	uracil-dna glycosylase
VCA1552_RS13475	COG0668	transmembrane transport
VCA1552_RS13480	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VCA1552_RS13485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCA1552_RS13535	COG1012	belongs to the aldehyde dehydrogenase family
VCA1552_RS13535	COG1454	alcohol dehydrogenase
VCA1552_RS13540	COG0318	PFAM AMP-dependent synthetase and ligase
VCA1552_RS13570	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
VCA1552_RS13575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCA1552_RS13580	COG0662	Cupin 2, conserved barrel domain protein
VCA1552_RS13580	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
VCA1552_RS13585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCA1552_RS13620	COG1519	Transferase
VCA1552_RS13650	COG3642	lipopolysaccharide core region biosynthetic process
VCA1552_RS13655	COG0859	PFAM glycosyl transferase family 9
VCA1552_RS13660	COG0463	Glycosyl transferase, family 2
VCA1552_RS13665	COG0859	PFAM glycosyl transferase family 9
VCA1552_RS13670	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VCA1552_RS13675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VCA1552_RS13685	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VCA1552_RS13690	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VCA1552_RS13695	COG2003	Belongs to the UPF0758 family
VCA1552_RS13705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VCA1552_RS13715	COG1309	transcriptional regulator
VCA1552_RS13720	COG1560	Kdo2-lipid A biosynthetic process
VCA1552_RS13725	COG1560	Kdo2-lipid A biosynthetic process
VCA1552_RS13730	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VCA1552_RS13735	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VCA1552_RS13740	COG1561	YicC-like family, N-terminal region
VCA1552_RS13745	COG2862	Uncharacterized protein family, UPF0114
VCA1552_RS13750	COG1263	PTS System
VCA1552_RS13750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCA1552_RS13755	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCA1552_RS13780	COG1120	ATPase activity
VCA1552_RS13785	COG4774	siderophore transport
VCA1552_RS13790	COG1132	(ABC) transporter
VCA1552_RS13805	COG0514	ATP-dependent DNA helicase (RecQ)
VCA1552_RS13810	COG2962	Rard protein
VCA1552_RS13825	COG1280	lysine exporter protein (LysE YggA)
VCA1552_RS13840	COG0210	DNA helicase
VCA1552_RS13850	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VCA1552_RS13855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCA1552_RS13905	COG3621	Patatin-like phospholipase
VCA1552_RS13930	COG2131	deaminase
VCA1552_RS13940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCA1552_RS13945	COG0601	transmembrane transport
VCA1552_RS13950	COG0747	negative chemotaxis
VCA1552_RS14005	COG1309	transcriptional regulator
VCA1552_RS14010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCA1552_RS14015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCA1552_RS14020	COG2960	long-chain fatty acid transporting porin activity
VCA1552_RS14025	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VCA1552_RS14030	COG0583	DNA-binding transcription factor activity
VCA1552_RS14075	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
VCA1552_RS14080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCA1552_RS14085	COG1739	Uncharacterized protein family UPF0029
VCA1552_RS14095	COG0183	Belongs to the thiolase family
VCA1552_RS14100	COG0583	DNA-binding transcription factor activity
VCA1552_RS14105	COG2814	Major facilitator Superfamily
VCA1552_RS14110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VCA1552_RS14115	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VCA1552_RS14120	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VCA1552_RS14125	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VCA1552_RS14130	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VCA1552_RS14135	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VCA1552_RS14140	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VCA1552_RS14150	COG0356	it plays a direct role in the translocation of protons across the membrane
VCA1552_RS14155	COG3312	ion transport
VCA1552_RS14160	COG1475	DNA binding
VCA1552_RS14165	COG1192	Involved in chromosome partitioning
VCA1552_RS14175	COG0445	tRNA wobble uridine modification
VCA1552_RS14185	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCA1552_RS14190	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VCA1552_RS14195	COG0706	membrane insertase activity
VCA1552_RS14205	COG0594	ribonuclease P activity
VCA1552_RS14210	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VCA1552_RS14215	COG1126	abc transporter atp-binding protein
VCA1552_RS14255	COG0217	transcriptional regulatory protein
VCA1552_RS14260	COG2084	Dehydrogenase
VCA1552_RS14280	COG2909	trisaccharide binding
VCA1552_RS14285	COG0058	SHG alpha-glucan phosphorylase activity
VCA1552_RS14290	COG1640	4-alpha-glucanotransferase
VCA1552_RS14295	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
VCA1552_RS14310	COG3501	Rhs element vgr protein
VCA1552_RS14315	COG4104	PAAR repeat-containing protein
VCA1552_RS14345	COG0471	metal ion transport
VCA1552_RS14350	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCA1552_RS14395	COG0671	phosphoesterase, PA-phosphatase related
VCA1552_RS14400	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
VCA1552_RS14410	COG1999	signal sequence binding
VCA1552_RS14425	COG0786	glutamate:sodium symporter activity
VCA1552_RS14445	COG1566	PFAM secretion protein HlyD family protein
VCA1552_RS14470	COG0813	purine-nucleoside phosphorylase activity
VCA1552_RS14480	COG3272	Protein of unknown function (DUF1722)
VCA1552_RS14490	COG0415	Belongs to the DNA photolyase family
VCA1552_RS14495	COG1388	LysM domain
VCA1552_RS14495	COG1376	ErfK ybiS ycfS ynhG family protein
VCA1552_RS14505	COG0513	Belongs to the DEAD box helicase family
VCA1552_RS14510	COG1770	oligopeptidase
VCA1552_RS14540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCA1552_RS14545	COG0573	inorganic phosphate transmembrane transporter activity
VCA1552_RS14550	COG0581	inorganic phosphate transmembrane transporter activity
VCA1552_RS14555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCA1552_RS14575	COG3314	Sporulation integral membrane protein YlbJ
VCA1552_RS14580	COG0659	secondary active sulfate transmembrane transporter activity
VCA1552_RS14590	COG0739	heme binding
VCA1552_RS14595	COG3300	MHYT domain
VCA1552_RS14595	COG5001	Diguanylate cyclase
VCA1552_RS14600	COG0583	DNA-binding transcription factor activity
VCA1552_RS14605	COG2814	Major facilitator Superfamily
VCA1552_RS14630	COG1301	dicarboxylic acid transport
VCA1552_RS14640	COG1342	Belongs to the UPF0251 family
VCA1552_RS14675	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
VCA1552_RS14680	COG0673	inositol 2-dehydrogenase activity
VCA1552_RS14690	COG2771	luxR family
VCA1552_RS14690	COG2200	EAL domain
VCA1552_RS14695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCA1552_RS14705	COG0564	pseudouridine synthase activity
VCA1552_RS14770	COG3829	transcription factor binding
VCA1552_RS14800	COG3501	Rhs element vgr protein
VCA1552_RS14800	COG3409	Peptidoglycan-binding domain 1 protein
VCA1552_RS14815	COG1869	D-ribose catabolic process
VCA1552_RS14820	COG1129	ABC transporter
VCA1552_RS14825	COG1172	Belongs to the binding-protein-dependent transport system permease family
VCA1552_RS14830	COG1879	ABC-type sugar transport system periplasmic component
VCA1552_RS14835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCA1552_RS14840	COG1609	Transcriptional regulator
VCA1552_RS14850	COG3201	nicotinamide mononucleotide transporter
VCA1552_RS14855	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCA1552_RS14865	COG0584	glycerophosphoryl diester phosphodiesterase
VCA1552_RS14870	COG2271	Major facilitator Superfamily
VCA1552_RS14910	COG0579	oxidoreductase
VCA1552_RS14920	COG0242	peptide deformylase activity
VCA1552_RS14930	COG1320	monovalent cation:proton antiporter activity
VCA1552_RS14935	COG2212	antiporter activity
VCA1552_RS14940	COG1863	multisubunit Na H antiporter MnhE subunit
VCA1552_RS14945	COG0651	ATP synthesis coupled electron transport
VCA1552_RS14950	COG1006	Multisubunit Na H antiporter MnhC subunit
VCA1552_RS14955	COG2111	Na H antiporter
VCA1552_RS14955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCA1552_RS14965	COG0589	response to stress
VCA1552_RS14970	COG0814	amino acid
VCA1552_RS14990	COG3530	Putative quorum-sensing-regulated virulence factor
VCA1552_RS15000	COG5002	protein histidine kinase activity
VCA1552_RS15000	COG5001	Diguanylate cyclase
VCA1552_RS15005	COG1278	Cold shock
VCA1552_RS15020	COG2304	oxidoreductase activity
VCA1552_RS15040	COG0714	Associated with various cellular activities
VCA1552_RS15045	COG0840	transmembrane signaling receptor activity
VCA1552_RS15060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCA1552_RS15065	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCA1552_RS15075	COG3604	Transcriptional regulator
VCA1552_RS15080	COG1017	nitric oxide dioxygenase activity
VCA1552_RS15080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
VCA1552_RS15085	COG1278	Cold shock
VCA1552_RS15090	COG3036	rescue of stalled ribosome
VCA1552_RS15115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
VCA1552_RS15115	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
VCA1552_RS15120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCA1552_RS15130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCA1552_RS15145	COG0516	GMP reductase activity
VCA1552_RS15185	COG0513	Belongs to the DEAD box helicase family
VCA1552_RS15190	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCA1552_RS15195	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
VCA1552_RS15200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
VCA1552_RS15210	COG3437	response regulator, receiver
VCA1552_RS15210	COG0784	Response regulator, receiver
VCA1552_RS15215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCA1552_RS15215	COG4191	Histidine kinase
VCA1552_RS15225	COG1757	Na H antiporter
VCA1552_RS15230	COG2814	Major facilitator Superfamily
VCA1552_RS15240	COG3706	GGDEF domain
VCA1552_RS15245	COG3240	lipase activity
VCA1552_RS15255	COG0840	transmembrane signaling receptor activity
VCA1552_RS15260	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
VCA1552_RS15265	COG5380	lipid catabolic process
VCA1552_RS15290	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCA1552_RS15295	COG4605	iron ion homeostasis
VCA1552_RS15300	COG4604	ABC transporter, ATP-binding protein
VCA1552_RS15305	COG2207	Transcriptional regulator
VCA1552_RS15320	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
VCA1552_RS15340	COG0745	RESPONSE REGULATOR receiver
VCA1552_RS15350	COG3623	hexulose-6-phosphate isomerase
VCA1552_RS15355	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
VCA1552_RS15360	COG0561	phosphatase activity
VCA1552_RS15390	COG3038	cytochrome b561
VCA1552_RS15395	COG0366	Alpha amylase catalytic
VCA1552_RS15420	COG0745	RESPONSE REGULATOR receiver
VCA1552_RS15425	COG5002	protein histidine kinase activity
VCA1552_RS15450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCA1552_RS15465	COG2814	Major facilitator Superfamily
VCA1552_RS15480	COG1686	Belongs to the peptidase S11 family
VCA1552_RS15510	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCA1552_RS15510	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
VCA1552_RS15515	COG0509	glycine decarboxylation via glycine cleavage system
VCA1552_RS15520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCA1552_RS15530	COG0404	The glycine cleavage system catalyzes the degradation of glycine
VCA1552_RS15540	COG3039	Transposase
VCA1552_RS15575	COG0291	Belongs to the bacterial ribosomal protein bL35 family
VCA1552_RS15580	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
VCA1552_RS15650	COG1028	Short-chain dehydrogenase reductase Sdr
VCA1552_RS15690	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VCA1552_RS15720	COG0494	nUDIX hydrolase
VCA1552_RS15745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCA1552_RS15750	COG3040	lipid binding
VCA1552_RS15785	COG3041	Addiction module toxin RelE StbE family
VCA1552_RS15895	COG1619	proteins homologs of microcin C7 resistance protein MccF
VCA1552_RS15950	COG0346	lactoylglutathione lyase activity
VCA1552_RS15970	COG3040	lipid binding
VCA1552_RS15990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
VCA1552_RS16000	COG1280	lysine exporter protein (LysE YggA)
VCA1552_RS16230	COG3549	Plasmid maintenance system killer
VCA1552_RS16235	COG3093	addiction module antidote protein HigA
VCA1552_RS16260	COG0384	phenazine biosynthesis protein PhzF
VCA1552_RS16295	COG0346	lactoylglutathione lyase activity
VCA1552_RS16335	COG3040	lipid binding
VCA1552_RS16395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCA1552_RS16425	COG0384	phenazine biosynthesis protein PhzF
VCA1552_RS16525	COG1619	proteins homologs of microcin C7 resistance protein MccF
VCA1552_RS16550	COG3040	lipid binding
VCA1552_RS16620	COG4977	sequence-specific DNA binding
VCA1552_RS16730	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
VCA1552_RS16735	COG2944	sequence-specific DNA binding
VCA1552_RS16745	COG3039	Transposase
VCA1552_RS16750	COG0110	maltose O-acetyltransferase activity
VCA1552_RS16770	COG0346	lactoylglutathione lyase activity
VCA1552_RS16935	COG0346	lactoylglutathione lyase activity
VCA1552_RS16960	COG1328	CTP reductase activity
VCA1552_RS16965	COG0602	queuosine metabolic process
VCA1552_RS16975	COG0189	ligase activity
VCA1552_RS16975	COG4067	protein conserved in archaea
VCA1552_RS16980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCA1552_RS16980	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
VCA1552_RS16980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCA1552_RS16985	COG1105	Belongs to the carbohydrate kinase PfkB family
VCA1552_RS16990	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCA1552_RS16990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCA1552_RS16995	COG1609	Transcriptional regulator
VCA1552_RS17000	COG0420	3'-5' exonuclease activity
VCA1552_RS17005	COG0419	ATPase involved in DNA repair
VCA1552_RS17010	COG0784	Response regulator, receiver
VCA1552_RS17010	COG2205	protein histidine kinase activity
VCA1552_RS17020	COG0156	8-amino-7-oxononanoate synthase activity
VCA1552_RS17035	COG0523	cobalamin synthesis protein
VCA1552_RS17050	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
VCA1552_RS17050	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
VCA1552_RS17050	COG1013	pyruvate-flavodoxin oxidoreductase activity
VCA1552_RS17050	COG0674	pyruvate-flavodoxin oxidoreductase activity
VCA1552_RS17055	COG2205	protein histidine kinase activity
VCA1552_RS17060	COG0745	RESPONSE REGULATOR receiver
VCA1552_RS17065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCA1552_RS17070	COG0586	Pfam SNARE associated Golgi protein
VCA1552_RS17080	COG2200	EAL domain
VCA1552_RS17090	COG3038	cytochrome b561
VCA1552_RS17100	COG2116	formate transmembrane transporter activity
VCA1552_RS17105	COG0583	DNA-binding transcription factor activity
VCA1552_RS17115	COG3593	DNA synthesis involved in DNA repair
VCA1552_RS17120	COG0737	Belongs to the 5'-nucleotidase family
VCA1552_RS17135	COG2824	Alkylphosphonate utilization operon protein PhnA
VCA1552_RS17170	COG2199	diguanylate cyclase activity
VCA1552_RS17190	COG3706	GGDEF domain
VCA1552_RS17205	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
VCA1552_RS17210	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
VCA1552_RS17220	COG0745	RESPONSE REGULATOR receiver
VCA1552_RS17235	COG3140	Belongs to the UPF0181 family
VCA1552_RS17240	COG0023	Translation Initiation Factor
VCA1552_RS17260	COG1042	CoA-binding domain protein
VCA1552_RS17260	COG0045	succinate-CoA ligase (ADP-forming) activity
VCA1552_RS17260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCA1552_RS17265	COG0583	DNA-binding transcription factor activity
VCA1552_RS17270	COG4771	TonB-dependent receptor
VCA1552_RS17270	COG1629	transport
VCA1552_RS17285	COG2050	protein possibly involved in aromatic compounds catabolism
VCA1552_RS17310	COG0625	glutathione transferase activity
VCA1552_RS17325	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
VCA1552_RS17330	COG4172	Belongs to the ABC transporter superfamily
VCA1552_RS17335	COG4239	(ABC) transporter, permease
VCA1552_RS17340	COG4174	ABC transporter (Permease)
VCA1552_RS17345	COG4166	transmembrane transport
VCA1552_RS17370	COG3104	oligopeptide transport
VCA1552_RS17390	COG3842	ATPase activity
VCA1552_RS17400	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCA1552_RS17405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCA1552_RS17410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCA1552_RS17415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCA1552_RS17420	COG1011	Hydrolase
VCA1552_RS17430	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
VCA1552_RS17435	COG1970	mechanosensitive ion channel activity
VCA1552_RS17440	COG2759	Belongs to the formate--tetrahydrofolate ligase family
VCA1552_RS17445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCA1552_RS17445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCA1552_RS17450	COG0302	gtp cyclohydrolase
VCA1552_RS17460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCA1552_RS17470	COG2897	thiosulfate sulfurtransferase activity
VCA1552_RS17475	COG2390	Transcriptional regulator
VCA1552_RS17490	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
VCA1552_RS17515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCA1552_RS17540	COG0583	DNA-binding transcription factor activity
VCA1552_RS17545	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
VCA1552_RS17590	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCA1552_RS17635	COG1263	PTS System
VCA1552_RS17635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCA1552_RS17640	COG1609	Transcriptional regulator
VCA1552_RS17645	COG1621	beta-fructofuranosidase activity
VCA1552_RS17650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCA1552_RS17655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCA1552_RS17665	COG2885	chlorophyll binding
VCA1552_RS17670	COG0545	Peptidyl-prolyl cis-trans isomerase
VCA1552_RS17675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
VCA1552_RS17680	COG0840	transmembrane signaling receptor activity
VCA1552_RS17690	COG3069	C4-dicarboxylate transmembrane transporter activity
VCA1552_RS17695	COG1760	l-serine dehydratase
VCA1552_RS17715	COG1609	Transcriptional regulator
VCA1552_RS17720	COG2197	response regulator
VCA1552_RS17725	COG3850	Histidine kinase
VCA1552_RS17730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCA1552_RS17740	COG0243	molybdopterin cofactor binding
VCA1552_RS17760	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCA1552_RS17765	COG2197	response regulator
VCA1552_RS17770	COG3851	Histidine kinase
VCA1552_RS17775	COG2271	Major facilitator Superfamily
VCA1552_RS17780	COG1840	ABC-type Fe3 transport system, periplasmic component
VCA1552_RS17790	COG3842	ATPase activity
VCA1552_RS17795	COG3243	poly(R)-hydroxyalkanoic acid synthase
VCA1552_RS17805	COG0183	Belongs to the thiolase family
VCA1552_RS17815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCA1552_RS17820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCA1552_RS17840	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
VCA1552_RS17850	COG1979	alcohol dehydrogenase
VCA1552_RS17865	COG4191	Histidine kinase
VCA1552_RS17875	COG2271	Major facilitator Superfamily
VCA1552_RS17880	COG0469	pyruvate kinase activity
VCA1552_RS17885	COG2205	protein histidine kinase activity
VCA1552_RS17885	COG2198	Histidine kinase
VCA1552_RS17885	COG0784	Response regulator, receiver
VCA1552_RS17890	COG1879	ABC-type sugar transport system periplasmic component
VCA1552_RS17895	COG1803	Methylglyoxal synthase
VCA1552_RS17900	COG1335	isochorismatase
VCA1552_RS17905	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
VCA1552_RS17920	COG0210	DNA helicase
VCA1552_RS17925	COG1289	transmembrane transporter activity
VCA1552_RS17955	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
VCA1552_RS17960	COG4149	molybdate abc transporter
VCA1552_RS17965	COG0725	ABC transporter, periplasmic molybdate-binding protein
VCA1552_RS17970	COG1492	cobalamin metabolic process
VCA1552_RS18015	COG0784	Response regulator, receiver
VCA1552_RS18015	COG5002	protein histidine kinase activity
VCA1552_RS18020	COG1879	ABC-type sugar transport system periplasmic component
VCA1552_RS18030	COG2827	Endonuclease containing a URI domain
VCA1552_RS18045	COG2926	Belongs to the UPF0265 family
VCA1552_RS18060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
VCA1552_RS18065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
VCA1552_RS18070	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
VCA1552_RS18075	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
VCA1552_RS18080	COG0247	lactate metabolic process
VCA1552_RS18085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCA1552_RS18090	COG3118	belongs to the thioredoxin family
VCA1552_RS18120	COG0583	DNA-binding transcription factor activity
VCA1552_RS18125	COG4160	amino acid transport
VCA1552_RS18130	COG4215	(ABC) transporter
VCA1552_RS18135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCA1552_RS18140	COG1126	abc transporter atp-binding protein
VCA1552_RS18150	COG2425	protein containing a von Willebrand factor type A (vWA) domain
VCA1552_RS18160	COG0494	nUDIX hydrolase
VCA1552_RS18165	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
VCA1552_RS18175	COG1309	transcriptional regulator
VCA1552_RS18180	COG0513	Belongs to the DEAD box helicase family
VCA1552_RS18185	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
VCA1552_RS18195	COG0814	amino acid
VCA1552_RS18200	COG0840	transmembrane signaling receptor activity
VCA1552_RS18205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
VCA1552_RS18215	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
VCA1552_RS18225	COG1984	allophanate hydrolase subunit 2
VCA1552_RS18240	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
VCA1552_RS18245	COG4181	ATPase activity
VCA1552_RS18255	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCA1552_RS18260	COG1716	ATPase activity
VCA1552_RS18260	COG5001	Diguanylate cyclase
VCA1552_RS18275	COG0484	heat shock protein binding
VCA1552_RS18315	COG0546	phosphoglycolate phosphatase activity
VCA1552_RS18330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCA1552_RS18335	COG1368	sulfuric ester hydrolase activity
VCA1552_RS18345	COG0513	Belongs to the DEAD box helicase family
VCA1552_RS18360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
VCA1552_RS18370	COG3046	protein related to deoxyribodipyrimidine photolyase
VCA1552_RS18380	COG3227	Zinc metalloprotease (Elastase)
VCA1552_RS18390	COG0010	Belongs to the arginase family
VCA1552_RS18395	COG1166	arginine decarboxylase activity
VCA1552_RS18405	COG2239	Acts as a magnesium transporter
VCA1552_RS18410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCA1552_RS18415	COG0459	protein refolding
VCA1552_RS18425	COG0527	aspartate kinase activity
VCA1552_RS18430	COG0662	Cupin 2, conserved barrel domain protein
VCA1552_RS18435	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
VCA1552_RS18440	COG0456	acetyltransferase
VCA1552_RS18450	COG3186	Phenylalanine-4-hydroxylase
VCA1552_RS18455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCA1552_RS18475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCA1552_RS18500	COG1253	flavin adenine dinucleotide binding
VCA1552_RS18505	COG1765	OsmC-like protein
VCA1552_RS18530	COG0531	amino acid
VCA1552_RS18545	COG3279	Response regulator of the LytR AlgR family
VCA1552_RS18550	COG3275	phosphorelay sensor kinase activity
VCA1552_RS18565	COG0577	efflux transmembrane transporter activity
VCA1552_RS18565	COG1136	(ABC) transporter
VCA1552_RS18570	COG1136	(ABC) transporter
VCA1552_RS18585	COG4989	oxidoreductase activity
VCA1552_RS18590	COG0366	Alpha amylase catalytic
VCA1552_RS18600	COG2067	long-chain fatty acid transport protein
VCA1552_RS18605	COG2267	carboxylic ester hydrolase activity
VCA1552_RS18615	COG3227	Zinc metalloprotease (Elastase)
VCA1552_RS18625	COG3047	cAMP biosynthetic process
VCA1552_RS18635	COG1686	Belongs to the peptidase S11 family
VCA1552_RS18640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
VCA1552_RS18645	COG1271	oxidase subunit
VCA1552_RS18650	COG1294	oxidase, subunit
VCA1552_RS18670	COG3048	D-serine ammonia-lyase activity
VCA1552_RS18675	COG0583	DNA-binding transcription factor activity
VCA1552_RS18725	COG1063	alcohol dehydrogenase
VCA1552_RS18755	COG0346	lactoylglutathione lyase activity
VCA1552_RS18775	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
VCA1552_RS18780	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCA1552_RS18785	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
VCA1552_RS18790	COG0363	glucosamine-6-phosphate deaminase activity
VCA1552_RS18795	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
VCA1552_RS18820	COG1929	Belongs to the glycerate kinase type-1 family
VCA1552_RS18825	COG2610	gluconate transmembrane transporter activity
VCA1552_RS18830	COG3835	regulator
VCA1552_RS18840	COG0748	coenzyme F420 binding
VCA1552_RS18845	COG3721	Heme iron utilization protein
VCA1552_RS18855	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCA1552_RS18860	COG0811	peptide transport
VCA1552_RS18865	COG0848	biopolymer transport protein
VCA1552_RS18870	COG4558	Periplasmic binding protein
VCA1552_RS18875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCA1552_RS18880	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
VCA1552_RS18915	COG3217	Mosc domain protein beta barrel domain protein
VCA1552_RS18915	COG0633	Ferredoxin
VCA1552_RS18915	COG3217	Mosc domain protein beta barrel domain protein
VCA1552_RS18915	COG0633	Ferredoxin
VCA1552_RS18925	COG0418	dihydroorotase activity
VCA1552_RS18935	COG3152	Membrane
VCA1552_RS18945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCA1552_RS18950	COG2354	Protein conserved in bacteria
VCA1552_RS18955	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
VCA1552_RS18960	COG1278	Cold shock
VCA1552_RS18990	COG2199	diguanylate cyclase activity
VCA1552_RS18995	COG1349	DNA-binding transcription factor activity
VCA1552_RS19010	COG3833	ABC-type maltose transport systems, permease component
VCA1552_RS19015	COG1175	transmembrane transport
VCA1552_RS19025	COG3842	ATPase activity
VCA1552_RS19030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCA1552_RS19045	COG0393	Putative heavy-metal-binding
VCA1552_RS19055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCA1552_RS19060	COG0835	chemotaxis
VCA1552_RS19060	COG0784	Response regulator, receiver
VCA1552_RS19065	COG1846	Transcriptional regulator
VCA1552_RS19070	COG3706	GGDEF domain
VCA1552_RS19110	COG0583	DNA-binding transcription factor activity
VCA1552_RS19115	COG5001	Diguanylate cyclase
VCA1552_RS19125	COG1741	Belongs to the pirin family
VCA1552_RS19130	COG3123	guanosine phosphorylase activity
VCA1552_RS19140	COG2211	Major facilitator Superfamily
VCA1552_RS19150	COG0840	transmembrane signaling receptor activity
VCA1552_RS19155	COG1067	ATP-dependent peptidase activity
VCA1552_RS19165	COG4172	Belongs to the ABC transporter superfamily
VCA1552_RS19190	COG0583	DNA-binding transcription factor activity
VCA1552_RS19195	COG1620	l-lactate permease
VCA1552_RS19210	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
VCA1552_RS19220	COG0840	transmembrane signaling receptor activity
VCA1552_RS19230	COG0513	Belongs to the DEAD box helicase family
VCA1552_RS19235	COG0583	DNA-binding transcription factor activity
VCA1552_RS19245	COG1902	pentaerythritol trinitrate reductase activity
VCA1552_RS19255	COG1132	(ABC) transporter
VCA1552_RS19265	COG1902	pentaerythritol trinitrate reductase activity
VCA1552_RS19275	COG1280	lysine exporter protein (LysE YggA)
VCA1552_RS19280	COG2207	Transcriptional regulator
VCA1552_RS19300	COG1846	Transcriptional regulator
VCA1552_RS19305	COG1764	response to oxidative stress
VCA1552_RS19310	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCA1552_RS19315	COG0697	spore germination
VCA1552_RS19325	COG0700	Nucleoside recognition
VCA1552_RS19330	COG3366	ferrous iron transmembrane transporter activity
VCA1552_RS19335	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
VCA1552_RS19345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
VCA1552_RS19350	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
VCA1552_RS19355	COG2259	Doxx family
VCA1552_RS19380	COG0363	glucosamine-6-phosphate deaminase activity
VCA1552_RS19395	COG4580	involved in the transport of maltose and maltodextrins
VCA1552_RS19410	COG0840	transmembrane signaling receptor activity
VCA1552_RS19425	COG0840	transmembrane signaling receptor activity
VCA1552_RS19435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCA1552_RS19440	COG1126	abc transporter atp-binding protein
VCA1552_RS19450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCA1552_RS19455	COG4597	amino acid ABC transporter
VCA1552_RS19460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCA1552_RS19470	COG0739	heme binding
VCA1552_RS19480	COG2213	PTS system mannitol-specific
VCA1552_RS19480	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCA1552_RS19485	COG0246	Mannitol dehydrogenase
VCA1552_RS19490	COG3722	fumarate hydratase activity
VCA1552_RS19495	COG0673	inositol 2-dehydrogenase activity
VCA1552_RS19525	COG2910	NAD(P)H-binding
VCA1552_RS19535	COG0840	transmembrane signaling receptor activity
VCA1552_RS19545	COG4221	oxidoreductase activity
VCA1552_RS19555	COG1901	pseudouridine methyltransferase
VCA1552_RS19570	COG0531	amino acid
VCA1552_RS19575	COG1982	Orn Lys Arg decarboxylase major
VCA1552_RS19610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
VCA1552_RS19635	COG1262	PFAM Formylglycine-generating sulfatase enzyme
VCA1552_RS19675	COG0745	RESPONSE REGULATOR receiver
VCA1552_RS19700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCA1552_RS19705	COG0840	transmembrane signaling receptor activity
VCA1552_RS19710	COG0835	chemotaxis
VCA1552_RS19715	COG0835	chemotaxis
VCA1552_RS19720	COG2198	Histidine kinase
VCA1552_RS19720	COG0643	Histidine kinase
VCA1552_RS19740	COG0601	transmembrane transport
VCA1552_RS19745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCA1552_RS19755	COG2194	sulfuric ester hydrolase activity
VCA1552_RS19760	COG0642	Histidine kinase
VCA1552_RS19795	COG1444	tRNA N-acetyltransferase activity
VCA1552_RS19800	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine