locus-tag	class	description
IT766_RS00035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IT766_RS00045	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IT766_RS00055	COG1072	(Pantothenic acid kinase))
IT766_RS00080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IT766_RS00085	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IT766_RS00090	COG0250	Participates in transcription elongation, termination and antitermination
IT766_RS00095	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IT766_RS00105	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IT766_RS00110	COG0222	ribosome binding
IT766_RS00115	COG0085	RNA polymerase activity
IT766_RS00120	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IT766_RS00125	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
IT766_RS00130	COG2816	NAD+ diphosphatase activity
IT766_RS00135	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IT766_RS00150	COG4942	peptidase
IT766_RS00155	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IT766_RS00165	COG0471	metal ion transport
IT766_RS00170	COG0688	phosphatidylethanolamine metabolic process
IT766_RS00175	COG1162	GTPase activity
IT766_RS00180	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IT766_RS00235	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IT766_RS00240	COG0802	atpase or kinase
IT766_RS00250	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IT766_RS00255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IT766_RS00260	COG1923	regulation of RNA biosynthetic process
IT766_RS00265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IT766_RS00270	COG0330	HflC and HflK could
IT766_RS00275	COG0330	HflC and HflK could
IT766_RS00280	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IT766_RS00285	COG2900	Belongs to the SlyX family
IT766_RS00295	COG0545	Peptidyl-prolyl cis-trans isomerase
IT766_RS00300	COG2964	Protein conserved in bacteria
IT766_RS00305	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IT766_RS00310	COG2923	Belongs to the DsrF TusC family
IT766_RS00320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IT766_RS00325	COG0049	tRNA binding
IT766_RS00330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IT766_RS00335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IT766_RS00340	COG2906	2 iron, 2 sulfur cluster binding
IT766_RS00350	COG0360	Binds together with S18 to 16S ribosomal RNA
IT766_RS00355	COG2965	DNA replication, synthesis of RNA primer
IT766_RS00360	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IT766_RS00365	COG0359	binds to the 23S rRNA
IT766_RS00380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IT766_RS00385	COG0432	Pfam Uncharacterised protein family UPF0047
IT766_RS00405	COG0735	belongs to the Fur family
IT766_RS00410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IT766_RS00435	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IT766_RS00445	COG0175	sulfate reduction
IT766_RS00515	COG1410	methionine synthase
IT766_RS00515	COG0646	methionine synthase
IT766_RS00520	COG0527	aspartate kinase activity
IT766_RS00525	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IT766_RS00535	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IT766_RS00550	COG0629	single-stranded DNA binding
IT766_RS00555	COG2200	EAL domain
IT766_RS00555	COG2199	diguanylate cyclase activity
IT766_RS00580	COG3267	Type II secretory pathway component ExeA
IT766_RS00580	COG3409	Peptidoglycan-binding domain 1 protein
IT766_RS00590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IT766_RS00595	COG1459	type II secretion system
IT766_RS00605	COG2165	general secretion pathway protein
IT766_RS00610	COG2165	general secretion pathway protein
IT766_RS00640	COG1077	Cell shape determining protein MreB Mrl
IT766_RS00645	COG1792	Involved in formation and maintenance of cell shape
IT766_RS00650	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IT766_RS00655	COG0424	maF-like protein
IT766_RS00665	COG3164	Protein of unknown function
IT766_RS00670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IT766_RS00675	COG0312	modulator of DNA gyrase
IT766_RS00680	COG2235	arginine
IT766_RS00700	COG0589	response to stress
IT766_RS00710	COG2358	TRAP transporter, solute receptor (TAXI family
IT766_RS00715	COG1438	arginine binding
IT766_RS00720	COG0039	L-malate dehydrogenase activity
IT766_RS00725	COG0531	amino acid
IT766_RS00730	COG0142	geranyltranstransferase activity
IT766_RS00735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IT766_RS00740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IT766_RS00745	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IT766_RS00750	COG2966	Psort location CytoplasmicMembrane, score
IT766_RS00755	COG3610	response to peptide
IT766_RS00765	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IT766_RS00770	COG2967	ApaG domain
IT766_RS00775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IT766_RS00780	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IT766_RS00785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IT766_RS00790	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IT766_RS00795	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IT766_RS00850	COG0741	lytic transglycosylase activity
IT766_RS00855	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IT766_RS00860	COG1194	a g-specific adenine glycosylase
IT766_RS00870	COG2066	Belongs to the glutaminase family
IT766_RS00880	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IT766_RS00890	COG1872	DUF167
IT766_RS00895	COG0762	integral membrane protein
IT766_RS00900	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IT766_RS00905	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IT766_RS00925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IT766_RS00930	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IT766_RS00935	COG1678	Uncharacterized ACR, COG1678
IT766_RS00940	COG0189	ligase activity
IT766_RS00945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IT766_RS00950	COG2356	endonuclease I
IT766_RS00960	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IT766_RS00965	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IT766_RS00970	COG0583	DNA-binding transcription factor activity
IT766_RS00975	COG4771	TonB-dependent receptor
IT766_RS00980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IT766_RS00985	COG0126	phosphoglycerate kinase activity
IT766_RS00990	COG0191	fructose-bisphosphate aldolase activity
IT766_RS00995	COG0668	transmembrane transport
IT766_RS01000	COG1279	arginine transmembrane transporter activity
IT766_RS01020	COG1349	DNA-binding transcription factor activity
IT766_RS01030	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IT766_RS01085	COG0328	RNA-DNA hybrid ribonuclease activity
IT766_RS01100	COG4969	Belongs to the N-Me-Phe pilin family
IT766_RS01110	COG0739	heme binding
IT766_RS01140	COG2003	Belongs to the UPF0758 family
IT766_RS01165	COG0582	viral genome integration into host DNA
IT766_RS01180	COG0358	DNA primase activity
IT766_RS01185	COG1610	YqeY-like protein
IT766_RS01190	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IT766_RS01195	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IT766_RS01205	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IT766_RS01210	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IT766_RS01215	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IT766_RS01220	COG1968	undecaprenyl-diphosphatase activity
IT766_RS01225	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IT766_RS01230	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IT766_RS01235	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IT766_RS01240	COG0585	pseudouridine synthase activity
IT766_RS01245	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IT766_RS01250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IT766_RS01260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IT766_RS01265	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IT766_RS01285	COG4208	sulfate ABC transporter
IT766_RS01290	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IT766_RS01300	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IT766_RS01310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IT766_RS01315	COG0527	aspartate kinase activity
IT766_RS01320	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IT766_RS01365	COG3630	sodium ion export across plasma membrane
IT766_RS01370	COG0511	ligase activity, forming carbon-carbon bonds
IT766_RS01370	COG5016	pyruvate
IT766_RS01375	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
IT766_RS01385	COG1238	metal cluster binding
IT766_RS01390	COG0612	Peptidase, M16
IT766_RS01395	COG2918	glutathione biosynthetic process
IT766_RS01400	COG1854	S-ribosylhomocysteine lyase activity
IT766_RS01405	COG4536	flavin adenine dinucleotide binding
IT766_RS01410	COG4137	Cytochrome C assembly protein
IT766_RS01415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IT766_RS01420	COG0228	four-way junction DNA binding
IT766_RS01425	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IT766_RS01430	COG0336	Belongs to the RNA methyltransferase TrmD family
IT766_RS01435	COG0335	large ribosomal subunit rRNA binding
IT766_RS01440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IT766_RS01445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IT766_RS01460	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IT766_RS01465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IT766_RS01470	COG0723	plastoquinol--plastocyanin reductase activity
IT766_RS01475	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IT766_RS01480	COG2857	Cytochrome c1
IT766_RS01485	COG0625	glutathione transferase activity
IT766_RS01490	COG2969	positive regulation of protein catabolic process
IT766_RS01495	COG2823	Periplasmic or secreted lipoprotein
IT766_RS01500	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IT766_RS01505	COG0792	nuclease activity
IT766_RS01510	COG3107	peptidoglycan biosynthetic process
IT766_RS01515	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IT766_RS01530	COG0288	reversible hydration of carbon dioxide
IT766_RS01535	COG0659	secondary active sulfate transmembrane transporter activity
IT766_RS01540	COG1131	(ABC) transporter
IT766_RS01545	COG0842	Transport permease protein
IT766_RS01550	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IT766_RS01555	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IT766_RS01560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IT766_RS01570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IT766_RS01580	COG1489	DNA binding
IT766_RS01590	COG1643	Atp-dependent helicase
IT766_RS01595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IT766_RS01605	COG1049	propionate catabolic process, 2-methylcitrate cycle
IT766_RS01610	COG3112	Uncharacterised protein family (UPF0231)
IT766_RS01615	COG0347	Belongs to the P(II) protein family
IT766_RS01620	COG0004	ammonium transporteR
IT766_RS01625	COG1840	ABC-type Fe3 transport system, periplasmic component
IT766_RS01655	COG2971	BadF BadG BcrA BcrD
IT766_RS01665	COG4608	Belongs to the ABC transporter superfamily
IT766_RS01670	COG0444	Belongs to the ABC transporter superfamily
IT766_RS01675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IT766_RS01680	COG0601	transmembrane transport
IT766_RS01685	COG0747	negative chemotaxis
IT766_RS01690	COG2205	protein histidine kinase activity
IT766_RS01690	COG0784	Response regulator, receiver
IT766_RS01695	COG2813	Specifically methylates the guanine in position
IT766_RS01700	COG0628	permease
IT766_RS01705	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IT766_RS01710	COG0316	Belongs to the HesB IscA family
IT766_RS01725	COG0739	heme binding
IT766_RS01730	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IT766_RS01735	COG2027	D-alanyl-D-alanine carboxypeptidase
IT766_RS01740	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IT766_RS01745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IT766_RS01750	COG1534	Rna-binding protein
IT766_RS01755	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IT766_RS01760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IT766_RS01765	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IT766_RS01775	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IT766_RS01790	COG0779	Required for maturation of 30S ribosomal subunits
IT766_RS01795	COG0195	Participates in both transcription termination and antitermination
IT766_RS01800	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IT766_RS01805	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IT766_RS01815	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IT766_RS01840	COG0826	peptidase U32
IT766_RS01845	COG0826	peptidase U32
IT766_RS01855	COG3154	lipid carrier protein
IT766_RS01860	COG3153	acetyltransferase
IT766_RS01885	COG0513	Belongs to the DEAD box helicase family
IT766_RS01905	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IT766_RS01910	COG2204	response regulator
IT766_RS01920	COG0667	Aldo Keto reductase
IT766_RS01930	COG0494	nUDIX hydrolase
IT766_RS01935	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
IT766_RS01940	COG0730	response to heat
IT766_RS01945	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IT766_RS01955	COG1283	sodium-dependent phosphate transmembrane transporter activity
IT766_RS01960	COG0583	DNA-binding transcription factor activity
IT766_RS01965	COG0640	Transcriptional regulator
IT766_RS01970	COG0268	Binds directly to 16S ribosomal RNA
IT766_RS01975	COG0728	peptidoglycan biosynthetic process
IT766_RS01980	COG0196	riboflavin kinase activity
IT766_RS01995	COG1047	Peptidyl-prolyl cis-trans
IT766_RS02000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IT766_RS02005	COG1966	Carbon starvation protein
IT766_RS02020	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IT766_RS02025	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IT766_RS02035	COG3279	Response regulator of the LytR AlgR family
IT766_RS02040	COG3275	phosphorelay sensor kinase activity
IT766_RS02045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IT766_RS02050	COG1605	Chorismate mutase
IT766_RS02050	COG0287	Prephenate dehydrogenase
IT766_RS02060	COG0488	(ABC) transporter
IT766_RS02070	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
IT766_RS02080	COG5001	Diguanylate cyclase
IT766_RS02085	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IT766_RS02090	COG1605	Chorismate mutase
IT766_RS02090	COG0077	Prephenate dehydratase
IT766_RS02095	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IT766_RS02100	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IT766_RS02105	COG0564	pseudouridine synthase activity
IT766_RS02115	COG0542	response to heat
IT766_RS02155	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IT766_RS02160	COG0826	peptidase U32
IT766_RS02170	COG0745	RESPONSE REGULATOR receiver
IT766_RS02175	COG5002	protein histidine kinase activity
IT766_RS02185	COG0248	Ppx GppA phosphatase
IT766_RS02190	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IT766_RS02200	COG0581	inorganic phosphate transmembrane transporter activity
IT766_RS02205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IT766_RS02220	COG3142	Participates in the control of copper homeostasis
IT766_RS02225	COG0450	alkyl hydroperoxide reductase
IT766_RS02230	COG0583	DNA-binding transcription factor activity
IT766_RS02235	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IT766_RS02245	COG0517	IMP dehydrogenase activity
IT766_RS02260	COG1862	Preprotein translocase
IT766_RS02265	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IT766_RS02270	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IT766_RS02275	COG0483	inositol monophosphate 1-phosphatase activity
IT766_RS02285	COG1959	2 iron, 2 sulfur cluster binding
IT766_RS02290	COG1104	cysteine desulfurase activity
IT766_RS02295	COG0822	iron-sulfur transferase activity
IT766_RS02305	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IT766_RS02310	COG0443	Heat shock 70 kDa protein
IT766_RS02315	COG0633	Ferredoxin
IT766_RS02320	COG2975	iron-sulfur cluster assembly
IT766_RS02325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IT766_RS02330	COG0105	UTP biosynthetic process
IT766_RS02335	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IT766_RS02345	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IT766_RS02350	COG0124	histidyl-tRNA synthetase
IT766_RS02355	COG2976	Protein conserved in bacteria
IT766_RS02360	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IT766_RS02365	COG1160	GTP binding
IT766_RS02380	COG1570	exodeoxyribonuclease VII activity
IT766_RS02385	COG0516	GMP reductase activity
IT766_RS02385	COG0517	IMP dehydrogenase activity
IT766_RS02390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IT766_RS02390	COG0519	Catalyzes the synthesis of GMP from XMP
IT766_RS02400	COG1584	GPR1 FUN34 yaaH family protein
IT766_RS02405	COG1535	isochorismatase
IT766_RS02405	COG3433	isochorismatase activity
IT766_RS02410	COG1021	2,3-dihydroxybenzoate-AMP ligase
IT766_RS02415	COG1169	isochorismate synthase
IT766_RS02420	COG1028	Short-chain dehydrogenase reductase Sdr
IT766_RS02430	COG4592	Periplasmic binding protein
IT766_RS02435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IT766_RS02440	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IT766_RS02445	COG1120	ATPase activity
IT766_RS02455	COG0583	DNA-binding transcription factor activity
IT766_RS02460	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IT766_RS02465	COG1115	amino acid carrier protein
IT766_RS02475	COG0583	DNA-binding transcription factor activity
IT766_RS02490	COG4565	transcriptional regulatory protein
IT766_RS02500	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
IT766_RS02505	COG5016	pyruvate
IT766_RS02505	COG0511	ligase activity, forming carbon-carbon bonds
IT766_RS02510	COG3630	sodium ion export across plasma membrane
IT766_RS02520	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IT766_RS02530	COG2301	Belongs to the HpcH HpaI aldolase family
IT766_RS02535	COG3051	citrate lyase alpha subunit
IT766_RS02555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IT766_RS02560	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IT766_RS02565	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
IT766_RS02620	COG1012	belongs to the aldehyde dehydrogenase family
IT766_RS02640	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IT766_RS02645	COG0840	transmembrane signaling receptor activity
IT766_RS02650	COG3710	Transcriptional regulator
IT766_RS02660	COG2165	general secretion pathway protein
IT766_RS02675	COG4796	Type ii and iii secretion system protein
IT766_RS02695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IT766_RS02700	COG1459	type II secretion system
IT766_RS02710	COG2207	Transcriptional regulator
IT766_RS02715	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IT766_RS02735	COG0739	heme binding
IT766_RS02750	COG0582	viral genome integration into host DNA
IT766_RS02760	COG0582	viral genome integration into host DNA
IT766_RS02770	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IT766_RS02775	COG2867	negative regulation of translational initiation
IT766_RS02780	COG2914	Belongs to the UPF0125 (RnfH) family
IT766_RS02785	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IT766_RS02795	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IT766_RS02805	COG0443	Heat shock 70 kDa protein
IT766_RS02810	COG0484	heat shock protein binding
IT766_RS02840	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IT766_RS02850	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IT766_RS02860	COG0047	phosphoribosylformylglycinamidine synthase activity
IT766_RS02860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IT766_RS02885	COG0442	prolyl-tRNA aminoacylation
IT766_RS02890	COG1720	tRNA m6t6A37 methyltransferase activity
IT766_RS02895	COG0254	rRNA binding
IT766_RS02900	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IT766_RS02905	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IT766_RS02910	COG1671	Belongs to the UPF0178 family
IT766_RS02920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IT766_RS02935	COG3098	single-species biofilm formation
IT766_RS02940	COG0564	pseudouridine synthase activity
IT766_RS02945	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IT766_RS02950	COG0142	geranyltranstransferase activity
IT766_RS02955	COG1722	exodeoxyribonuclease VII activity
IT766_RS02960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IT766_RS02970	COG0301	tRNA thio-modification
IT766_RS02970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IT766_RS02975	COG0583	DNA-binding transcription factor activity
IT766_RS02980	COG2363	Small membrane protein
IT766_RS02985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IT766_RS02990	COG1611	Belongs to the LOG family
IT766_RS03005	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IT766_RS03005	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IT766_RS03015	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
IT766_RS03020	COG1464	Belongs to the NlpA lipoprotein family
IT766_RS03025	COG2011	ABC-type metal ion transport system permease component
IT766_RS03030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IT766_RS03035	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IT766_RS03040	COG1609	Transcriptional regulator
IT766_RS03045	COG1263	PTS System
IT766_RS03045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT766_RS03050	COG0366	Alpha amylase catalytic
IT766_RS03080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IT766_RS03085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IT766_RS03090	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IT766_RS03095	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IT766_RS03100	COG0110	maltose O-acetyltransferase activity
IT766_RS03120	COG1045	serine acetyltransferase
IT766_RS03130	COG0438	transferase activity, transferring glycosyl groups
IT766_RS03140	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IT766_RS03170	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IT766_RS03175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IT766_RS03185	COG1596	polysaccharide export
IT766_RS03210	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IT766_RS03220	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IT766_RS03225	COG0321	lipoyl(octanoyl) transferase activity
IT766_RS03230	COG2921	Belongs to the UPF0250 family
IT766_RS03235	COG1686	Belongs to the peptidase S11 family
IT766_RS03240	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IT766_RS03245	COG0772	Belongs to the SEDS family
IT766_RS03250	COG0768	penicillin binding
IT766_RS03255	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IT766_RS03260	COG0799	negative regulation of ribosome biogenesis
IT766_RS03265	COG1466	dna polymerase III delta subunit
IT766_RS03270	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
IT766_RS03275	COG0495	leucyl-tRNA aminoacylation
IT766_RS03280	COG2888	peptidyl-tyrosine sulfation
IT766_RS03285	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IT766_RS03290	COG4535	Mg2 and Co2 transporter CorC
IT766_RS03300	COG1702	phosphate starvation-inducible protein PhoH
IT766_RS03305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IT766_RS03310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IT766_RS03315	COG2190	(PTS) system
IT766_RS03325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IT766_RS03330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IT766_RS03335	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
IT766_RS03340	COG3115	cell septum assembly
IT766_RS03345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IT766_RS03360	COG0789	Transcriptional regulator
IT766_RS03365	COG1585	Membrane protein implicated in regulation of membrane protease activity
IT766_RS03370	COG0330	HflC and HflK could
IT766_RS03375	COG3118	belongs to the thioredoxin family
IT766_RS03380	COG0300	oxidoreductase activity
IT766_RS03385	COG1090	epimerase
IT766_RS03390	COG0622	Phosphoesterase
IT766_RS03405	COG3710	Transcriptional regulator
IT766_RS03410	COG0326	Molecular chaperone. Has ATPase activity
IT766_RS03415	COG0563	adenylate kinase activity
IT766_RS03420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IT766_RS03435	COG0367	asparagine synthase
IT766_RS03440	COG4651	solute:proton antiporter activity
IT766_RS03440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IT766_RS03445	COG1846	Transcriptional regulator
IT766_RS03445	COG1940	carbohydrate kinase activity
IT766_RS03450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IT766_RS03455	COG1263	PTS System
IT766_RS03455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT766_RS03455	COG2190	(PTS) system
IT766_RS03470	COG0101	tRNA pseudouridine synthase activity
IT766_RS03475	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IT766_RS03480	COG0285	dihydrofolate synthase activity
IT766_RS03485	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IT766_RS03490	COG1286	toxin biosynthetic process
IT766_RS03495	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IT766_RS03500	COG2056	Na+-H+ antiporter family
IT766_RS03505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IT766_RS03520	COG0346	lactoylglutathione lyase activity
IT766_RS03525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IT766_RS03545	COG4656	Part of a membrane complex involved in electron transport
IT766_RS03550	COG2878	Part of a membrane complex involved in electron transport
IT766_RS03555	COG4657	Part of a membrane complex involved in electron transport
IT766_RS03565	COG0556	nucleotide-excision repair
IT766_RS03570	COG2204	response regulator
IT766_RS03575	COG2198	Histidine kinase
IT766_RS03580	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IT766_RS03585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IT766_RS03590	COG0521	Mo-molybdopterin cofactor biosynthetic process
IT766_RS03595	COG0315	cyclic pyranopterin monophosphate synthase activity
IT766_RS03600	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IT766_RS03605	COG0314	molybdopterin synthase activity
IT766_RS03610	COG2199	diguanylate cyclase activity
IT766_RS03615	COG0617	tRNA 3'-terminal CCA addition
IT766_RS03615	COG0517	IMP dehydrogenase activity
IT766_RS03615	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IT766_RS03625	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
IT766_RS03635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IT766_RS03635	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IT766_RS03640	COG0489	protein tyrosine kinase activity
IT766_RS03645	COG0572	uridine kinase
IT766_RS03650	COG2982	Protein involved in outer membrane biogenesis
IT766_RS03655	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IT766_RS03660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IT766_RS03685	COG0183	Belongs to the thiolase family
IT766_RS03690	COG1250	3-hydroxyacyl-CoA dehydrogenase
IT766_RS03690	COG1024	Enoyl-CoA hydratase
IT766_RS03695	COG0778	Nitroreductase
IT766_RS03700	COG0583	DNA-binding transcription factor activity
IT766_RS03705	COG0745	RESPONSE REGULATOR receiver
IT766_RS03710	COG2832	Protein of unknown function (DUF454)
IT766_RS03715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IT766_RS03725	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IT766_RS03730	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IT766_RS03740	COG2983	Belongs to the UPF0260 family
IT766_RS03745	COG1028	Short-chain dehydrogenase reductase Sdr
IT766_RS03750	COG0616	signal peptide processing
IT766_RS03760	COG1522	sequence-specific DNA binding
IT766_RS03765	COG1946	Acyl-CoA thioesterase
IT766_RS03785	COG3706	GGDEF domain
IT766_RS03795	COG0640	Transcriptional regulator
IT766_RS03800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IT766_RS03825	COG1881	PFAM PEBP family protein
IT766_RS03840	COG0009	L-threonylcarbamoyladenylate synthase
IT766_RS03855	COG2201	protein-glutamate methylesterase activity
IT766_RS03865	COG5002	protein histidine kinase activity
IT766_RS03870	COG4191	Histidine kinase
IT766_RS03875	COG5001	Diguanylate cyclase
IT766_RS03875	COG3300	MHYT domain
IT766_RS03880	COG2204	response regulator
IT766_RS03900	COG0601	transmembrane transport
IT766_RS03905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IT766_RS03910	COG0444	Belongs to the ABC transporter superfamily
IT766_RS03915	COG4608	Belongs to the ABC transporter superfamily
IT766_RS03920	COG0435	Glutathione S-transferase
IT766_RS03925	COG0857	belongs to the CobB CobQ family
IT766_RS03925	COG0280	phosphate acetyltransferase
IT766_RS03930	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IT766_RS03935	COG3092	negative regulation of chromosome organization
IT766_RS03940	COG4628	conserved protein (DUF2132)
IT766_RS03950	COG4120	Belongs to the binding-protein-dependent transport system permease family
IT766_RS03960	COG2199	diguanylate cyclase activity
IT766_RS03960	COG2203	Gaf domain
IT766_RS03965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IT766_RS03975	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IT766_RS03980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IT766_RS03985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IT766_RS03990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IT766_RS03995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IT766_RS04000	COG0156	8-amino-7-oxononanoate synthase activity
IT766_RS04005	COG2226	methyltransferase
IT766_RS04010	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IT766_RS04020	COG0501	Belongs to the peptidase M48B family
IT766_RS04030	COG0300	oxidoreductase activity
IT766_RS04045	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IT766_RS04055	COG2268	Band 7 protein
IT766_RS04065	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IT766_RS04070	COG2915	High frequency lysogenization protein hflD homolog
IT766_RS04075	COG0482	sulfurtransferase activity
IT766_RS04080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IT766_RS04085	COG2916	Histone family protein nucleoid-structuring protein H-NS
IT766_RS04090	COG1757	Na H antiporter
IT766_RS04095	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IT766_RS04100	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IT766_RS04105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IT766_RS04110	COG0131	Imidazoleglycerol-phosphate dehydratase
IT766_RS04110	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IT766_RS04115	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IT766_RS04120	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IT766_RS04125	COG0107	imidazoleglycerol-phosphate synthase activity
IT766_RS04130	COG0140	phosphoribosyl-ATP diphosphatase activity
IT766_RS04130	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IT766_RS04135	COG1187	pseudouridine synthase activity
IT766_RS04145	COG1278	Cold shock
IT766_RS04150	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IT766_RS04155	COG0542	response to heat
IT766_RS04160	COG2985	domain, Protein
IT766_RS04160	COG3273	potassium ion transport
IT766_RS04165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IT766_RS04170	COG1454	alcohol dehydrogenase
IT766_RS04170	COG1012	belongs to the aldehyde dehydrogenase family
IT766_RS04175	COG1737	Transcriptional regulator
IT766_RS04180	COG0076	glutamate decarboxylase activity
IT766_RS04190	COG2431	L-lysine efflux transmembrane transporter activity
IT766_RS04200	COG3070	regulator of competence-specific genes
IT766_RS04215	COG3852	Histidine kinase
IT766_RS04225	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IT766_RS04240	COG0189	ligase activity
IT766_RS04240	COG4067	protein conserved in archaea
IT766_RS04245	COG0500	methyltransferase
IT766_RS04250	COG4106	trans-aconitate 2-methyltransferase activity
IT766_RS04255	COG1801	Protein of unknown function DUF72
IT766_RS04260	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IT766_RS04265	COG1435	thymidine kinase activity
IT766_RS04275	COG0159	tryptophan synthase activity
IT766_RS04280	COG0133	tryptophan synthase activity
IT766_RS04285	COG0134	indole-3-glycerol-phosphate synthase activity
IT766_RS04285	COG0135	phosphoribosylanthranilate isomerase activity
IT766_RS04290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IT766_RS04295	COG0512	Glutamine amidotransferase of anthranilate synthase
IT766_RS04300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IT766_RS04310	COG0613	PHP domain protein
IT766_RS04315	COG0009	L-threonylcarbamoyladenylate synthase
IT766_RS04320	COG1187	pseudouridine synthase activity
IT766_RS04325	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IT766_RS04330	COG4988	ABC transporter
IT766_RS04335	COG0492	ferredoxin-NADP+ reductase activity
IT766_RS04345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IT766_RS04355	COG2949	membrane
IT766_RS04365	COG0281	malic enzyme
IT766_RS04375	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IT766_RS04395	COG2885	chlorophyll binding
IT766_RS04410	COG0247	lactate metabolic process
IT766_RS04410	COG0277	FAD linked oxidase domain protein
IT766_RS04430	COG2986	histidine ammonia-lyase
IT766_RS04435	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IT766_RS04440	COG0010	Belongs to the arginase family
IT766_RS04445	COG1228	amidohydrolase
IT766_RS04460	COG3099	Belongs to the UPF0263 family
IT766_RS04465	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IT766_RS04475	COG5001	Diguanylate cyclase
IT766_RS04480	COG0417	DNA replication proofreading
IT766_RS04485	COG2197	response regulator
IT766_RS04530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IT766_RS04535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IT766_RS04535	COG0072	phenylalanine-tRNA ligase activity
IT766_RS04540	COG0776	regulation of translation
IT766_RS04570	COG1346	cytolysis
IT766_RS04575	COG1380	Effector of murein hydrolase LrgA
IT766_RS04580	COG2925	Exonuclease
IT766_RS04585	COG1823	symporter activity
IT766_RS04590	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IT766_RS04595	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IT766_RS04600	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IT766_RS04620	COG4139	cobalamin transport
IT766_RS04670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IT766_RS04675	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IT766_RS04680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IT766_RS04690	COG1054	Belongs to the UPF0176 family
IT766_RS04700	COG2814	Major facilitator Superfamily
IT766_RS04710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IT766_RS04735	COG2989	Protein conserved in bacteria
IT766_RS04740	COG3108	Peptidase M15
IT766_RS04745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IT766_RS04760	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IT766_RS04785	COG1846	Transcriptional regulator
IT766_RS04790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IT766_RS04795	COG0726	polysaccharide deacetylase
IT766_RS04800	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IT766_RS04810	COG1447	Phosphotransferase system cellobiose-specific component IIA
IT766_RS04815	COG1486	melibiose metabolic process
IT766_RS04825	COG1609	Transcriptional regulator
IT766_RS04830	COG2943	transferase activity, transferring hexosyl groups
IT766_RS04835	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
IT766_RS04840	COG0840	transmembrane signaling receptor activity
IT766_RS04855	COG1448	Aminotransferase
IT766_RS04865	COG0351	phosphomethylpyrimidine kinase
IT766_RS04870	COG0017	Asparaginyl-tRNA synthetase
IT766_RS04880	COG0720	synthase
IT766_RS04885	COG1760	l-serine dehydratase
IT766_RS04890	COG0814	amino acid
IT766_RS04895	COG0494	nUDIX hydrolase
IT766_RS04900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IT766_RS04915	COG3106	COG3106 Predicted ATPase
IT766_RS04920	COG3768	UPF0283 membrane protein
IT766_RS04930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IT766_RS04945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IT766_RS04955	COG0471	metal ion transport
IT766_RS04960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IT766_RS04960	COG4191	Histidine kinase
IT766_RS04970	COG2990	Protein conserved in bacteria
IT766_RS04975	COG3713	MltA-interacting MipA family protein
IT766_RS04980	COG2205	protein histidine kinase activity
IT766_RS04985	COG0745	RESPONSE REGULATOR receiver
IT766_RS05010	COG1129	ABC transporter
IT766_RS05050	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IT766_RS05055	COG0372	Belongs to the citrate synthase family
IT766_RS05090	COG2195	Cleaves the N-terminal amino acid of tripeptides
IT766_RS05100	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IT766_RS05110	COG0625	glutathione transferase activity
IT766_RS05115	COG3437	response regulator, receiver
IT766_RS05130	COG3706	GGDEF domain
IT766_RS05135	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IT766_RS05140	COG1254	Belongs to the acylphosphatase family
IT766_RS05145	COG2920	part of a sulfur-relay system
IT766_RS05150	COG0670	Belongs to the BI1 family
IT766_RS05155	COG1126	abc transporter atp-binding protein
IT766_RS05160	COG0765	amino acid transport
IT766_RS05165	COG4597	amino acid ABC transporter
IT766_RS05170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IT766_RS05180	COG0561	phosphatase activity
IT766_RS05185	COG0602	queuosine metabolic process
IT766_RS05190	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IT766_RS05220	COG3706	GGDEF domain
IT766_RS05225	COG0443	Heat shock 70 kDa protein
IT766_RS05230	COG0443	Heat shock 70 kDa protein
IT766_RS05260	COG1643	Atp-dependent helicase
IT766_RS05270	COG0443	Heat shock 70 kDa protein
IT766_RS05275	COG0095	Lipoate-protein ligase
IT766_RS05285	COG0583	DNA-binding transcription factor activity
IT766_RS05290	COG0477	Major facilitator Superfamily
IT766_RS05295	COG0415	Belongs to the DNA photolyase family
IT766_RS05310	COG0745	RESPONSE REGULATOR receiver
IT766_RS05320	COG0643	Histidine kinase
IT766_RS05320	COG2198	Histidine kinase
IT766_RS05325	COG0643	Histidine kinase
IT766_RS05325	COG0784	Response regulator, receiver
IT766_RS05325	COG2198	Histidine kinase
IT766_RS05330	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IT766_RS05340	COG2201	protein-glutamate methylesterase activity
IT766_RS05345	COG0835	chemotaxis
IT766_RS05350	COG3290	protein histidine kinase activity
IT766_RS05350	COG0840	transmembrane signaling receptor activity
IT766_RS05355	COG0840	transmembrane signaling receptor activity
IT766_RS05365	COG0513	Belongs to the DEAD box helicase family
IT766_RS05375	COG1538	Outer membrane efflux protein
IT766_RS05380	COG1566	PFAM secretion protein HlyD family protein
IT766_RS05385	COG2814	Major facilitator Superfamily
IT766_RS05395	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IT766_RS05405	COG3501	Rhs element vgr protein
IT766_RS05415	COG3675	Pfam Lipase (class 3)
IT766_RS05430	COG1280	lysine exporter protein (LysE YggA)
IT766_RS05435	COG1115	amino acid carrier protein
IT766_RS05450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IT766_RS05460	COG1177	transmembrane transport
IT766_RS05470	COG3842	ATPase activity
IT766_RS05495	COG0589	response to stress
IT766_RS05500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IT766_RS05515	COG2217	Heavy metal translocating P-type atpase
IT766_RS05525	COG2010	Cytochrome c
IT766_RS05540	COG3278	Belongs to the heme-copper respiratory oxidase family
IT766_RS05555	COG0784	Response regulator, receiver
IT766_RS05555	COG2205	protein histidine kinase activity
IT766_RS05580	COG2994	toxin metabolic process
IT766_RS05585	COG1073	alpha beta
IT766_RS05585	COG3064	Membrane
IT766_RS05585	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
IT766_RS05605	COG1476	TRANSCRIPTIONal
IT766_RS05620	COG4128	Pfam Zonular occludens toxin
IT766_RS05650	COG1476	TRANSCRIPTIONal
IT766_RS05725	COG3120	sequence-specific DNA binding
IT766_RS05730	COG1067	ATP-dependent peptidase activity
IT766_RS05735	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IT766_RS05750	COG0488	(ABC) transporter
IT766_RS05760	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IT766_RS05760	COG0116	Belongs to the methyltransferase superfamily
IT766_RS05770	COG0167	dihydroorotate dehydrogenase activity
IT766_RS05785	COG0308	aminopeptidase N
IT766_RS05820	COG0641	radical SAM
IT766_RS05900	COG4695	Portal protein
IT766_RS05980	COG1428	Deoxynucleoside kinase
IT766_RS06050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IT766_RS06055	COG0308	aminopeptidase N
IT766_RS06070	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IT766_RS06075	COG1956	GAF domain-containing protein
IT766_RS06080	COG1132	(ABC) transporter
IT766_RS06085	COG2995	paraquat-inducible protein a
IT766_RS06090	COG3008	intermembrane lipid transfer
IT766_RS06100	COG2996	Protein conserved in bacteria
IT766_RS06115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IT766_RS06120	COG1666	GTP binding
IT766_RS06125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IT766_RS06140	COG0437	4 iron, 4 sulfur cluster binding
IT766_RS06145	COG0243	molybdopterin cofactor binding
IT766_RS06145	COG3383	formate dehydrogenase (NAD+) activity
IT766_RS06175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IT766_RS06180	COG0488	(ABC) transporter
IT766_RS06185	COG3852	Histidine kinase
IT766_RS06190	COG2204	response regulator
IT766_RS06200	COG4662	Binding-protein-dependent transport system inner membrane component
IT766_RS06205	COG3842	ATPase activity
IT766_RS06210	COG0746	molybdenum cofactor guanylyltransferase activity
IT766_RS06235	COG1940	carbohydrate kinase activity
IT766_RS06240	COG3148	PFAM DTW domain containing protein
IT766_RS06250	COG0840	transmembrane signaling receptor activity
IT766_RS06255	COG0791	NLP P60 protein
IT766_RS06265	COG3001	Fructosamine kinase
IT766_RS06275	COG0534	Mate efflux family protein
IT766_RS06285	COG1793	dna ligase
IT766_RS06295	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IT766_RS06300	COG0848	biopolymer transport protein
IT766_RS06305	COG0811	peptide transport
IT766_RS06310	COG0811	peptide transport
IT766_RS06325	COG1175	transmembrane transport
IT766_RS06330	COG0395	ABC-type sugar transport system, permease component
IT766_RS06335	COG3842	ATPase activity
IT766_RS06340	COG1349	DNA-binding transcription factor activity
IT766_RS06345	COG0584	glycerophosphoryl diester phosphodiesterase
IT766_RS06350	COG2731	YhcH YjgK YiaL family protein
IT766_RS06355	COG0251	oxidation-reduction process
IT766_RS06360	COG1609	Transcriptional regulator
IT766_RS06365	COG2723	6-phospho-beta-galactosidase activity
IT766_RS06375	COG0583	DNA-binding transcription factor activity
IT766_RS06395	COG1136	(ABC) transporter
IT766_RS06395	COG0577	efflux transmembrane transporter activity
IT766_RS06400	COG1136	(ABC) transporter
IT766_RS06400	COG0577	efflux transmembrane transporter activity
IT766_RS06405	COG4591	ABC-type transport system involved in lipoprotein release permease component
IT766_RS06405	COG1136	(ABC) transporter
IT766_RS06410	COG1294	oxidase, subunit
IT766_RS06415	COG1271	oxidase subunit
IT766_RS06455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IT766_RS06465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IT766_RS06485	COG0753	catalase activity
IT766_RS06500	COG3527	Alpha-acetolactate decarboxylase
IT766_RS06515	COG2199	diguanylate cyclase activity
IT766_RS06515	COG2200	EAL domain
IT766_RS06525	COG2017	converts alpha-aldose to the beta-anomer
IT766_RS06530	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IT766_RS06535	COG1085	galactose-1-phosphate uridylyltransferase
IT766_RS06580	COG0835	chemotaxis
IT766_RS06580	COG0784	Response regulator, receiver
IT766_RS06590	COG4565	transcriptional regulatory protein
IT766_RS06595	COG3290	protein histidine kinase activity
IT766_RS06630	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IT766_RS06635	COG3063	Type IV pilus biogenesis stability protein PilW
IT766_RS06650	COG1451	nucleotide metabolic process
IT766_RS06660	COG0583	DNA-binding transcription factor activity
IT766_RS06680	COG1538	Outer membrane efflux protein
IT766_RS06695	COG1748	Saccharopine dehydrogenase
IT766_RS06705	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IT766_RS06715	COG0577	efflux transmembrane transporter activity
IT766_RS06720	COG4181	ATPase activity
IT766_RS06725	COG0534	Mate efflux family protein
IT766_RS06730	COG0702	epimerase
IT766_RS06740	COG2814	Major facilitator Superfamily
IT766_RS06745	COG1187	pseudouridine synthase activity
IT766_RS06750	COG1061	Type III restriction enzyme res subunit
IT766_RS06770	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IT766_RS06775	COG3706	GGDEF domain
IT766_RS06775	COG5001	Diguanylate cyclase
IT766_RS06775	COG2203	Gaf domain
IT766_RS06775	COG4251	negative regulation of phosphorylation
IT766_RS06785	COG0840	transmembrane signaling receptor activity
IT766_RS06815	COG4934	collagen metabolic process
IT766_RS06830	COG0784	Response regulator, receiver
IT766_RS06830	COG2205	protein histidine kinase activity
IT766_RS06835	COG2239	Acts as a magnesium transporter
IT766_RS06845	COG0814	amino acid
IT766_RS06850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IT766_RS06855	COG1131	(ABC) transporter
IT766_RS06860	COG0842	Transport permease protein
IT766_RS06870	COG3313	Fe-S protein
IT766_RS06880	COG4134	Bacterial extracellular solute-binding protein
IT766_RS06885	COG4135	transport system, permease component
IT766_RS06890	COG4136	ATPase activity
IT766_RS06895	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IT766_RS06900	COG0564	pseudouridine synthase activity
IT766_RS06905	COG0733	neurotransmitter:sodium symporter activity
IT766_RS06915	COG0626	cystathionine gamma-synthase activity
IT766_RS06920	COG2818	Glycosylase
IT766_RS06935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IT766_RS06950	COG1842	Phage shock protein A
IT766_RS06955	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IT766_RS06965	COG4168	peptide transport system, permease
IT766_RS06980	COG4172	Belongs to the ABC transporter superfamily
IT766_RS06995	COG1227	inorganic diphosphatase activity
IT766_RS07015	COG0243	molybdopterin cofactor binding
IT766_RS07020	COG3005	denitrification pathway
IT766_RS07025	COG4459	periplasmic nitrate reductase
IT766_RS07035	COG2116	formate transmembrane transporter activity
IT766_RS07045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IT766_RS07050	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IT766_RS07065	COG1607	acyl-coa hydrolase
IT766_RS07070	COG2350	Protein conserved in bacteria
IT766_RS07080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IT766_RS07085	COG0583	DNA-binding transcription factor activity
IT766_RS07100	COG0612	Peptidase, M16
IT766_RS07105	COG5001	Diguanylate cyclase
IT766_RS07110	COG1032	radical SAM domain protein
IT766_RS07130	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IT766_RS07140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IT766_RS07145	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IT766_RS07150	COG0745	RESPONSE REGULATOR receiver
IT766_RS07155	COG3381	protein complex oligomerization
IT766_RS07160	COG1609	Transcriptional regulator
IT766_RS07165	COG3070	regulator of competence-specific genes
IT766_RS07185	COG0297	glycogen (starch) synthase activity
IT766_RS07190	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IT766_RS07195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IT766_RS07220	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IT766_RS07225	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IT766_RS07250	COG1012	belongs to the aldehyde dehydrogenase family
IT766_RS07255	COG1309	transcriptional regulator
IT766_RS07275	COG0668	transmembrane transport
IT766_RS07280	COG2995	paraquat-inducible protein a
IT766_RS07285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IT766_RS07285	COG3008	intermembrane lipid transfer
IT766_RS07295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IT766_RS07310	COG0582	viral genome integration into host DNA
IT766_RS07315	COG0582	viral genome integration into host DNA
IT766_RS07320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IT766_RS07340	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IT766_RS07360	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IT766_RS07380	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
IT766_RS07385	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
IT766_RS07390	COG1737	Transcriptional regulator
IT766_RS07395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IT766_RS07400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IT766_RS07405	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IT766_RS07410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IT766_RS07420	COG1940	carbohydrate kinase activity
IT766_RS07425	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IT766_RS07430	COG4409	exo-alpha-(2->6)-sialidase activity
IT766_RS07440	COG2003	Belongs to the UPF0758 family
IT766_RS07455	COG3941	tape measure
IT766_RS07495	COG0488	(ABC) transporter
IT766_RS07575	COG0415	Belongs to the DNA photolyase family
IT766_RS07585	COG4628	conserved protein (DUF2132)
IT766_RS07590	COG3284	Transcriptional regulator
IT766_RS07595	COG1012	belongs to the aldehyde dehydrogenase family
IT766_RS07605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT766_RS07610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT766_RS07615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT766_RS07625	COG2207	Transcriptional regulator
IT766_RS07630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IT766_RS07630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT766_RS07630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT766_RS07635	COG1482	cell wall glycoprotein biosynthetic process
IT766_RS07645	COG5002	protein histidine kinase activity
IT766_RS07645	COG0784	Response regulator, receiver
IT766_RS07655	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IT766_RS07665	COG2885	chlorophyll binding
IT766_RS07670	COG0823	Involved in the tonB-independent uptake of proteins
IT766_RS07685	COG0811	peptide transport
IT766_RS07690	COG0824	Thioesterase
IT766_RS07695	COG3790	cyd operon protein YbgE
IT766_RS07700	COG4890	Cyd operon protein YbgT
IT766_RS07705	COG1294	oxidase, subunit
IT766_RS07710	COG1271	oxidase subunit
IT766_RS07720	COG0632	four-way junction helicase activity
IT766_RS07725	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IT766_RS07730	COG0215	cysteine-tRNA ligase activity
IT766_RS07735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IT766_RS07740	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IT766_RS07745	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IT766_RS07750	COG3012	SEC-C Motif Domain Protein
IT766_RS07755	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IT766_RS07760	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IT766_RS07765	COG1199	ATP-dependent helicase activity
IT766_RS07770	COG0730	response to heat
IT766_RS07775	COG3923	Primosomal replication protein n
IT766_RS07785	COG0840	transmembrane signaling receptor activity
IT766_RS07790	COG0708	Exodeoxyribonuclease III
IT766_RS07795	COG4160	amino acid transport
IT766_RS07820	COG1882	Formate acetyltransferase
IT766_RS07830	COG0840	transmembrane signaling receptor activity
IT766_RS07835	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IT766_RS07845	COG3013	Belongs to the UPF0304 family
IT766_RS07850	COG2766	serine protein kinase
IT766_RS07855	COG2718	Belongs to the UPF0229 family
IT766_RS07860	COG2719	SpoVR family
IT766_RS07865	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IT766_RS07870	COG2835	tetraacyldisaccharide 4'-kinase activity
IT766_RS07875	COG1663	tetraacyldisaccharide 4'-kinase activity
IT766_RS07880	COG1132	(ABC) transporter
IT766_RS07885	COG0658	competence protein
IT766_RS07885	COG2333	competence protein COMEC
IT766_RS07895	COG4591	ABC-type transport system involved in lipoprotein release permease component
IT766_RS07900	COG1136	(ABC) transporter
IT766_RS07905	COG4591	ABC-type transport system involved in lipoprotein release permease component
IT766_RS07915	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IT766_RS07935	COG1252	NADH dehydrogenase
IT766_RS07940	COG3150	esterase
IT766_RS07965	COG0537	adenosine 5'-monophosphoramidase activity
IT766_RS07980	COG2186	Transcriptional regulator
IT766_RS07985	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IT766_RS07990	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IT766_RS07995	COG1674	ftsk spoiiie
IT766_RS08005	COG0686	Belongs to the AlaDH PNT family
IT766_RS08015	COG0583	DNA-binding transcription factor activity
IT766_RS08035	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IT766_RS08040	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IT766_RS08045	COG0776	regulation of translation
IT766_RS08050	COG0539	negative regulation of cytoplasmic translation
IT766_RS08055	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IT766_RS08060	COG1555	photosystem II stabilization
IT766_RS08065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IT766_RS08070	COG0776	regulation of translation
IT766_RS08075	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IT766_RS08080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IT766_RS08090	COG0544	peptidyl-prolyl cis-trans isomerase activity
IT766_RS08100	COG4191	Histidine kinase
IT766_RS08110	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IT766_RS08115	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IT766_RS08120	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IT766_RS08125	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IT766_RS08135	COG3300	MHYT domain
IT766_RS08135	COG5001	Diguanylate cyclase
IT766_RS08145	COG4589	Belongs to the CDS family
IT766_RS08180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IT766_RS08190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IT766_RS08205	COG0243	molybdopterin cofactor binding
IT766_RS08210	COG3005	denitrification pathway
IT766_RS08215	COG3469	chitinase activity
IT766_RS08215	COG3325	Belongs to the glycosyl hydrolase 18 family
IT766_RS08220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IT766_RS08230	COG2951	lytic endotransglycosylase activity
IT766_RS08235	COG3100	YcgL domain-containing protein
IT766_RS08240	COG0850	regulation of cytokinetic process
IT766_RS08245	COG2894	cell division
IT766_RS08250	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IT766_RS08255	COG3015	lipoprotein NlpE involved in copper resistance
IT766_RS08275	COG0477	Major facilitator Superfamily
IT766_RS08285	COG0840	transmembrane signaling receptor activity
IT766_RS08290	COG1396	sequence-specific DNA binding
IT766_RS08295	COG3135	benzoate transporter
IT766_RS08315	COG0596	Alpha beta hydrolase
IT766_RS08320	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IT766_RS08325	COG1169	isochorismate synthase
IT766_RS08330	COG0436	Aminotransferase
IT766_RS08335	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IT766_RS08340	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IT766_RS08360	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IT766_RS08365	COG0318	PFAM AMP-dependent synthetase and ligase
IT766_RS08370	COG0596	Alpha beta hydrolase
IT766_RS08385	COG1214	PFAM Peptidase M22, glycoprotease
IT766_RS08390	COG1199	ATP-dependent helicase activity
IT766_RS08400	COG0788	formyltetrahydrofolate deformylase activity
IT766_RS08405	COG1902	pentaerythritol trinitrate reductase activity
IT766_RS08405	COG0446	pyridine nucleotide-disulphide oxidoreductase
IT766_RS08410	COG0616	signal peptide processing
IT766_RS08415	COG0252	asparaginase activity
IT766_RS08420	COG3139	Protein of unknown function (DUF1315)
IT766_RS08430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IT766_RS08435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IT766_RS08440	COG0676	glucose-6-phosphate 1-epimerase activity
IT766_RS08450	COG2226	methyltransferase
IT766_RS08465	COG0835	chemotaxis
IT766_RS08465	COG0784	Response regulator, receiver
IT766_RS08470	COG1940	carbohydrate kinase activity
IT766_RS08480	COG4667	esterase of the alpha-beta hydrolase superfamily
IT766_RS08495	COG0733	neurotransmitter:sodium symporter activity
IT766_RS08505	COG1263	PTS System
IT766_RS08505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT766_RS08510	COG0084	hydrolase, TatD family'
IT766_RS08520	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IT766_RS08525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IT766_RS08530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IT766_RS08535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IT766_RS08540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IT766_RS08545	COG1028	Short-chain dehydrogenase reductase Sdr
IT766_RS08555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IT766_RS08560	COG0416	fatty acid biosynthetic process
IT766_RS08565	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IT766_RS08570	COG1399	metal-binding, possibly nucleic acid-binding protein
IT766_RS08575	COG0424	maF-like protein
IT766_RS08585	COG1530	ribonuclease E activity
IT766_RS08590	COG0659	secondary active sulfate transmembrane transporter activity
IT766_RS08600	COG1454	alcohol dehydrogenase
IT766_RS08600	COG1012	belongs to the aldehyde dehydrogenase family
IT766_RS08605	COG2095	MarC family integral membrane protein
IT766_RS08610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IT766_RS08615	COG1757	Na H antiporter
IT766_RS08625	COG3081	Nucleoid-associated protein
IT766_RS08630	COG3082	Protein of unknown function (DUF1414)
IT766_RS08635	COG3083	sulfuric ester hydrolase activity
IT766_RS08650	COG0123	including yeast histone deacetylase and acetoin utilization protein
IT766_RS08655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IT766_RS08660	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IT766_RS08680	COG2853	Lipoprotein
IT766_RS08690	COG3088	subunit of a heme lyase
IT766_RS08690	COG4235	cytochrome complex assembly
IT766_RS08695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IT766_RS08700	COG1138	Cytochrome C-type biogenesis protein
IT766_RS08705	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IT766_RS08715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IT766_RS08720	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IT766_RS08725	COG4133	protoheme IX ABC transporter activity
IT766_RS08735	COG0835	chemotaxis
IT766_RS08745	COG1192	Involved in chromosome partitioning
IT766_RS08750	COG2201	protein-glutamate methylesterase activity
IT766_RS08755	COG2198	Histidine kinase
IT766_RS08755	COG0784	Response regulator, receiver
IT766_RS08755	COG0643	Histidine kinase
IT766_RS08760	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IT766_RS08790	COG2062	phosphohistidine phosphatase, SixA
IT766_RS08795	COG1025	Belongs to the peptidase M16 family
IT766_RS08805	COG0018	arginyl-trna synthetase
IT766_RS08825	COG1918	ferrous iron import across plasma membrane
IT766_RS08830	COG4977	sequence-specific DNA binding
IT766_RS08835	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IT766_RS08840	COG1121	(ABC) transporter
IT766_RS08845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IT766_RS08855	COG0045	succinate-CoA ligase (ADP-forming) activity
IT766_RS08860	COG0508	dehydrogenase complex catalyzes the overall conversion of
IT766_RS08865	COG0567	Dehydrogenase, E1 component
IT766_RS08875	COG1053	succinate dehydrogenase
IT766_RS08880	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IT766_RS08885	COG2009	succinate dehydrogenase
IT766_RS08890	COG0372	Belongs to the citrate synthase family
IT766_RS08895	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IT766_RS08905	COG0033	Phosphoglucomutase
IT766_RS08910	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IT766_RS08915	COG0596	Alpha beta hydrolase
IT766_RS08930	COG1346	cytolysis
IT766_RS08940	COG0583	DNA-binding transcription factor activity
IT766_RS08950	COG0735	belongs to the Fur family
IT766_RS08955	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IT766_RS08960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IT766_RS08965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IT766_RS08975	COG0431	NADPH-dependent FMN reductase
IT766_RS08985	COG3101	peptidyl-lysine hydroxylation
IT766_RS08990	COG2860	membrane
IT766_RS08995	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IT766_RS09000	COG2890	protein-(glutamine-N5) methyltransferase activity
IT766_RS09005	COG2840	Smr protein MutS2
IT766_RS09020	COG1987	bacterial-type flagellum assembly
IT766_RS09045	COG1580	Controls the rotational direction of flagella during chemotaxis
IT766_RS09070	COG1317	bacterial-type flagellum organization
IT766_RS09075	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IT766_RS09085	COG1677	Flagellar hook-basal body complex protein FliE
IT766_RS09105	COG1516	flagellar protein fliS
IT766_RS09115	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IT766_RS09120	COG1334	flagellar protein FlaG
IT766_RS09125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IT766_RS09130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IT766_RS09135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IT766_RS09140	COG2837	iron assimilation
IT766_RS09160	COG1393	Belongs to the ArsC family
IT766_RS09170	COG1876	peptidase activity
IT766_RS09180	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IT766_RS09195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IT766_RS09215	COG4783	chaperone-mediated protein folding
IT766_RS09220	COG1393	Belongs to the ArsC family
IT766_RS09240	COG2233	PERMEase
IT766_RS09245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IT766_RS09250	COG0737	Belongs to the 5'-nucleotidase family
IT766_RS09255	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IT766_RS09260	COG2912	Transglutaminase-like superfamily
IT766_RS09270	COG2890	protein-(glutamine-N5) methyltransferase activity
IT766_RS09275	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IT766_RS09280	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IT766_RS09285	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IT766_RS09290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IT766_RS09295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IT766_RS09300	COG0193	aminoacyl-tRNA hydrolase activity
IT766_RS09305	COG0012	GTP binding
IT766_RS09390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IT766_RS09395	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IT766_RS09410	COG3951	Flagellar rod assembly protein muramidase FlgJ
IT766_RS09410	COG1705	Flagellar rod assembly protein muramidase FlgJ
IT766_RS09415	COG1706	bacterial-type flagellum-dependent cell motility
IT766_RS09420	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IT766_RS09430	COG4787	bacterial-type flagellum-dependent cell motility
IT766_RS09435	COG1749	Flagellar hook protein flgE
IT766_RS09450	COG1815	bacterial-type flagellum-dependent cell motility
IT766_RS09455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IT766_RS09460	COG0835	chemotaxis
IT766_RS09460	COG0784	Response regulator, receiver
IT766_RS09495	COG3433	isochorismatase activity
IT766_RS09495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IT766_RS09495	COG2226	methyltransferase
IT766_RS09500	COG2375	cellular response to nickel ion
IT766_RS09505	COG4774	siderophore transport
IT766_RS09505	COG1629	transport
IT766_RS09520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IT766_RS09540	COG3735	TraB family
IT766_RS09555	COG2840	Smr protein MutS2
IT766_RS09560	COG1187	pseudouridine synthase activity
IT766_RS09570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IT766_RS09575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IT766_RS09580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IT766_RS09585	COG0121	glutamine amidotransferase
IT766_RS09590	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IT766_RS09595	COG1960	acyl-CoA dehydrogenase activity
IT766_RS09610	COG0328	RNA-DNA hybrid ribonuclease activity
IT766_RS09615	COG2226	methyltransferase
IT766_RS09620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IT766_RS09625	COG1388	LysM domain
IT766_RS09625	COG0741	lytic transglycosylase activity
IT766_RS09630	COG3021	interspecies interaction between organisms
IT766_RS09635	COG0347	Belongs to the P(II) protein family
IT766_RS09650	COG0037	tRNA processing
IT766_RS09655	COG0825	malonyl-CoA metabolic process
IT766_RS09660	COG0587	DNA-directed DNA polymerase activity
IT766_RS09665	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IT766_RS09670	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IT766_RS09675	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IT766_RS09680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IT766_RS09685	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IT766_RS09690	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IT766_RS09700	COG0750	zinc metalloprotease
IT766_RS09705	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IT766_RS09710	COG0575	Belongs to the CDS family
IT766_RS09715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IT766_RS09720	COG0233	cytoplasmic translational termination
IT766_RS09725	COG0528	UMP kinase activity
IT766_RS09730	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IT766_RS09735	COG0052	Belongs to the universal ribosomal protein uS2 family
IT766_RS09740	COG0024	Methionine aminopeptidase
IT766_RS09745	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IT766_RS09755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IT766_RS09760	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IT766_RS09765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IT766_RS09770	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IT766_RS09785	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IT766_RS09785	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IT766_RS09790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IT766_RS09795	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IT766_RS09800	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IT766_RS09810	COG1073	alpha beta
IT766_RS09815	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IT766_RS09820	COG2252	PERMEase
IT766_RS09825	COG2195	Cleaves the N-terminal amino acid of tripeptides
IT766_RS09830	COG4067	protein conserved in archaea
IT766_RS09830	COG0189	ligase activity
IT766_RS09835	COG0189	ligase activity
IT766_RS09845	COG0733	neurotransmitter:sodium symporter activity
IT766_RS09850	COG3706	GGDEF domain
IT766_RS09870	COG1477	protein flavinylation
IT766_RS09875	COG2871	sodium ion transport
IT766_RS09880	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IT766_RS09885	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IT766_RS09890	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IT766_RS09895	COG1805	sodium ion transport
IT766_RS09900	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IT766_RS09905	COG0271	Belongs to the BolA IbaG family
IT766_RS09910	COG2813	Specifically methylates the guanine in position
IT766_RS09920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IT766_RS09925	COG2211	Major facilitator Superfamily
IT766_RS09935	COG1595	DNA-templated transcription, initiation
IT766_RS09945	COG3248	Nucleoside-binding outer membrane protein
IT766_RS09950	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IT766_RS09955	COG0693	protein deglycase activity
IT766_RS09960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IT766_RS09965	COG2166	iron-sulfur cluster assembly
IT766_RS09970	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IT766_RS09975	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IT766_RS09985	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IT766_RS09985	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IT766_RS09995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IT766_RS10000	COG1074	ATP-dependent DNA helicase activity
IT766_RS10005	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IT766_RS10020	COG3141	response to X-ray
IT766_RS10025	COG2171	N-acyltransferase activity
IT766_RS10035	COG0456	acetyltransferase
IT766_RS10040	COG0569	domain protein
IT766_RS10040	COG0189	ligase activity
IT766_RS10055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IT766_RS10060	COG1609	Transcriptional regulator
IT766_RS10065	COG3250	beta-galactosidase activity
IT766_RS10080	COG1022	Amp-dependent synthetase and ligase
IT766_RS10085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IT766_RS10090	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IT766_RS10100	COG0560	Phosphoserine phosphatase
IT766_RS10110	COG0813	purine-nucleoside phosphorylase activity
IT766_RS10115	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IT766_RS10120	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IT766_RS10125	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IT766_RS10135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IT766_RS10140	COG0084	hydrolase, TatD family'
IT766_RS10150	COG3022	response to hydroperoxide
IT766_RS10155	COG1115	amino acid carrier protein
IT766_RS10170	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IT766_RS10175	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IT766_RS10180	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
IT766_RS10185	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IT766_RS10210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IT766_RS10220	COG0745	RESPONSE REGULATOR receiver
IT766_RS10225	COG0784	Response regulator, receiver
IT766_RS10225	COG2198	Histidine kinase
IT766_RS10225	COG5002	protein histidine kinase activity
IT766_RS10230	COG5001	Diguanylate cyclase
IT766_RS10230	COG2203	Gaf domain
IT766_RS10230	COG3706	GGDEF domain
IT766_RS10230	COG4251	negative regulation of phosphorylation
IT766_RS10235	COG1242	4 iron, 4 sulfur cluster binding
IT766_RS10240	COG0070	glutamate synthase
IT766_RS10240	COG0067	glutamate synthase
IT766_RS10240	COG0069	glutamate synthase activity
IT766_RS10250	COG0069	glutamate synthase activity
IT766_RS10250	COG0070	glutamate synthase
IT766_RS10250	COG0067	glutamate synthase
IT766_RS10255	COG0493	'glutamate synthase
IT766_RS10265	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IT766_RS10275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IT766_RS10280	COG2860	membrane
IT766_RS10285	COG0583	DNA-binding transcription factor activity
IT766_RS10290	COG0730	response to heat
IT766_RS10300	COG4172	Belongs to the ABC transporter superfamily
IT766_RS10320	COG0505	Belongs to the CarA family
IT766_RS10330	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IT766_RS10335	COG0494	nUDIX hydrolase
IT766_RS10340	COG0653	protein targeting
IT766_RS10350	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IT766_RS10355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IT766_RS10360	COG0849	cell division
IT766_RS10365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IT766_RS10370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IT766_RS10380	COG0772	Belongs to the SEDS family
IT766_RS10385	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IT766_RS10395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IT766_RS10400	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IT766_RS10405	COG0768	penicillin binding
IT766_RS10410	COG3116	cell division
IT766_RS10425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IT766_RS10430	COG0508	dehydrogenase complex catalyzes the overall conversion of
IT766_RS10435	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IT766_RS10440	COG2186	Transcriptional regulator
IT766_RS10445	COG0737	Belongs to the 5'-nucleotidase family
IT766_RS10450	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IT766_RS10455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IT766_RS10460	COG4974	Belongs to the 'phage' integrase family
IT766_RS10465	COG0716	FMN binding
IT766_RS10485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IT766_RS10490	COG1459	type II secretion system
IT766_RS10500	COG0237	dephospho-CoA kinase activity
IT766_RS10505	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IT766_RS10515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IT766_RS10520	COG0187	DNA topoisomerase II activity
IT766_RS10525	COG3150	esterase
IT766_RS10535	COG3151	Protein conserved in bacteria
IT766_RS10540	COG0494	nUDIX hydrolase
IT766_RS10545	COG1538	Outer membrane efflux protein
IT766_RS10555	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IT766_RS10560	COG0840	transmembrane signaling receptor activity
IT766_RS10565	COG3025	triphosphatase activity
IT766_RS10570	COG1392	Phosphate transport regulator
IT766_RS10575	COG0306	phosphate transporter
IT766_RS10580	COG4991	sh3 domain protein
IT766_RS10590	COG3267	Type II secretory pathway component ExeA
IT766_RS10590	COG3409	Peptidoglycan-binding domain 1 protein
IT766_RS10600	COG0148	phosphopyruvate hydratase activity
IT766_RS10605	COG0504	CTP synthase activity
IT766_RS10610	COG3956	TIGRFAM MazG family protein
IT766_RS10615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IT766_RS10630	COG5001	Diguanylate cyclase
IT766_RS10650	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IT766_RS10655	COG1381	Involved in DNA repair and RecF pathway recombination
IT766_RS10660	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IT766_RS10675	COG0481	GTPase activity
IT766_RS10680	COG3086	response to oxidative stress
IT766_RS10695	COG1595	DNA-templated transcription, initiation
IT766_RS10700	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IT766_RS10710	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IT766_RS10725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IT766_RS10730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IT766_RS10735	COG3079	Belongs to the UPF0149 family
IT766_RS10740	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IT766_RS10750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IT766_RS10755	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IT766_RS10760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IT766_RS10765	COG0440	acetolactate synthase activity
IT766_RS10770	COG0028	Belongs to the TPP enzyme family
IT766_RS10780	COG0583	DNA-binding transcription factor activity
IT766_RS10805	COG0473	3-isopropylmalate dehydrogenase activity
IT766_RS10810	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IT766_RS10815	COG0066	3-isopropylmalate dehydratase activity
IT766_RS10860	COG3437	response regulator, receiver
IT766_RS10875	COG0795	lipopolysaccharide-transporting ATPase activity
IT766_RS10880	COG0795	lipopolysaccharide-transporting ATPase activity
IT766_RS10885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IT766_RS10890	COG2927	DNA polymerase III (CHI subunit)
IT766_RS10895	COG0525	valine-tRNA ligase activity
IT766_RS10900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IT766_RS10905	COG0564	pseudouridine synthase activity
IT766_RS10915	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IT766_RS10925	COG0540	Belongs to the ATCase OTCase family
IT766_RS10935	COG0251	oxidation-reduction process
IT766_RS10945	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IT766_RS10950	COG5007	Belongs to the BolA IbaG family
IT766_RS10960	COG2854	intermembrane phospholipid transfer
IT766_RS10965	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IT766_RS10970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IT766_RS10975	COG1127	ABC transporter
IT766_RS10985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IT766_RS10985	COG0517	IMP dehydrogenase activity
IT766_RS11000	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IT766_RS11005	COG1137	ATPase activity
IT766_RS11015	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IT766_RS11020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IT766_RS11025	COG1660	Displays ATPase and GTPase activities
IT766_RS11030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IT766_RS11035	COG2239	Acts as a magnesium transporter
IT766_RS11040	COG0312	modulator of DNA gyrase
IT766_RS11045	COG3028	Belongs to the UPF0307 family
IT766_RS11050	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IT766_RS11055	COG1178	ABC-type Fe3 transport system permease component
IT766_RS11065	COG0163	prenyltransferase activity
IT766_RS11070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IT766_RS11080	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IT766_RS11085	COG2105	PFAM AIG2 family protein
IT766_RS11095	COG0729	surface antigen
IT766_RS11100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IT766_RS11105	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IT766_RS11120	COG1136	(ABC) transporter
IT766_RS11140	COG0529	Catalyzes the synthesis of activated sulfate
IT766_RS11155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IT766_RS11155	COG1648	precorrin-2 dehydrogenase activity
IT766_RS11160	COG0737	Belongs to the 5'-nucleotidase family
IT766_RS11170	COG0513	Belongs to the DEAD box helicase family
IT766_RS11175	COG2153	protein acetylation
IT766_RS11180	COG0697	spore germination
IT766_RS11185	COG3266	domain, Protein
IT766_RS11185	COG3061	Opacity-associated protein A
IT766_RS11190	COG0545	Peptidyl-prolyl cis-trans isomerase
IT766_RS11200	COG0203	ribosomal protein L17
IT766_RS11205	COG0202	RNA polymerase activity
IT766_RS11210	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IT766_RS11215	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IT766_RS11220	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IT766_RS11225	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IT766_RS11230	COG0201	protein transport
IT766_RS11240	COG1841	ribosomal large subunit assembly
IT766_RS11245	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IT766_RS11250	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IT766_RS11260	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IT766_RS11265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IT766_RS11270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IT766_RS11275	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IT766_RS11280	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IT766_RS11285	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IT766_RS11290	COG0255	Belongs to the universal ribosomal protein uL29 family
IT766_RS11295	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IT766_RS11300	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IT766_RS11305	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IT766_RS11310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IT766_RS11315	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IT766_RS11320	COG0089	rRNA binding
IT766_RS11325	COG0088	Forms part of the polypeptide exit tunnel
IT766_RS11330	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IT766_RS11335	COG0051	transcription antitermination factor activity, RNA binding
IT766_RS11340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IT766_RS11345	COG0557	exoribonuclease II activity
IT766_RS11350	COG3083	sulfuric ester hydrolase activity
IT766_RS11355	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IT766_RS11370	COG1047	Peptidyl-prolyl cis-trans
IT766_RS11385	COG2249	NAD(P)H dehydrogenase (quinone) activity
IT766_RS11390	COG0488	(ABC) transporter
IT766_RS11400	COG0429	hydrolase of the alpha beta-hydrolase fold
IT766_RS11410	COG3954	Phosphoribulokinase
IT766_RS11425	COG1012	belongs to the aldehyde dehydrogenase family
IT766_RS11435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IT766_RS11445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IT766_RS11460	COG0180	Tryptophanyl-tRNA synthetase
IT766_RS11465	COG0546	phosphoglycolate phosphatase activity
IT766_RS11470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IT766_RS11475	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IT766_RS11485	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IT766_RS11490	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IT766_RS11520	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IT766_RS11530	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IT766_RS11530	COG0678	peroxiredoxin activity
IT766_RS11535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IT766_RS11545	COG0165	Argininosuccinate lyase
IT766_RS11550	COG0137	argininosuccinate synthase activity
IT766_RS11555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IT766_RS11560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IT766_RS11565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IT766_RS11570	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IT766_RS11580	COG1045	serine acetyltransferase
IT766_RS11585	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IT766_RS11590	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IT766_RS11595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IT766_RS11600	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IT766_RS11605	COG1053	succinate dehydrogenase
IT766_RS11610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IT766_RS11615	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
IT766_RS11625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IT766_RS11630	COG1509	lysine 2,3-aminomutase activity
IT766_RS11640	COG0459	protein refolding
IT766_RS11645	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IT766_RS11670	COG0149	triose-phosphate isomerase activity
IT766_RS11675	COG0534	Mate efflux family protein
IT766_RS11680	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IT766_RS11685	COG1575	Belongs to the MenA family. Type 1 subfamily
IT766_RS11690	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IT766_RS11695	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IT766_RS11700	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IT766_RS11705	COG1609	Transcriptional regulator
IT766_RS11710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IT766_RS11715	COG0254	rRNA binding
IT766_RS11720	COG0281	malic enzyme
IT766_RS11725	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
IT766_RS11730	COG0626	cystathionine gamma-synthase activity
IT766_RS11735	COG0527	aspartate kinase activity
IT766_RS11735	COG0460	homoserine dehydrogenase
IT766_RS11740	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IT766_RS11745	COG3074	FtsZ-dependent cytokinesis
IT766_RS11750	COG1494	fructose-1,6-bisphosphatase
IT766_RS11755	COG0205	6-phosphofructokinase activity
IT766_RS11760	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IT766_RS11770	COG0745	RESPONSE REGULATOR receiver
IT766_RS11775	COG2205	protein histidine kinase activity
IT766_RS11785	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IT766_RS11790	COG3030	protein affecting phage T7 exclusion by the F plasmid
IT766_RS11795	COG3706	GGDEF domain
IT766_RS11800	COG1027	Aspartate ammonia-lyase
IT766_RS11805	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IT766_RS11815	COG4232	protein-disulfide reductase activity
IT766_RS11835	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IT766_RS11840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IT766_RS11845	COG0194	GDP metabolic process
IT766_RS11850	COG1758	RNA polymerase activity
IT766_RS11855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IT766_RS11860	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IT766_RS11865	COG2233	PERMEase
IT766_RS11880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IT766_RS11885	COG2183	response to ionizing radiation
IT766_RS11895	COG0596	Alpha beta hydrolase
IT766_RS11905	COG1040	competence protein
IT766_RS11915	COG0494	nUDIX hydrolase
IT766_RS11920	COG1218	3'(2'),5'-bisphosphate nucleotidase
IT766_RS11930	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IT766_RS11935	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IT766_RS11945	COG4795	General secretion pathway protein
IT766_RS11950	COG2165	general secretion pathway protein
IT766_RS11955	COG2165	general secretion pathway protein
IT766_RS11960	COG2165	general secretion pathway protein
IT766_RS11965	COG1459	type II secretion system
IT766_RS11970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IT766_RS11980	COG3031	protein transport across the cell outer membrane
IT766_RS11985	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IT766_RS11990	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IT766_RS11995	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IT766_RS12005	COG0456	acetyltransferase
IT766_RS12010	COG1490	D-aminoacyl-tRNA deacylase activity
IT766_RS12015	COG1295	ribonuclease BN
IT766_RS12025	COG1217	gtp-binding protein TYPA
IT766_RS12035	COG0174	glutamine synthetase
IT766_RS12045	COG3852	Histidine kinase
IT766_RS12055	COG5001	Diguanylate cyclase
IT766_RS12055	COG3300	MHYT domain
IT766_RS12060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IT766_RS12130	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IT766_RS12135	COG1404	Belongs to the peptidase S8 family
IT766_RS12140	COG4206	TonB-dependent receptor
IT766_RS12145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IT766_RS12160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IT766_RS12165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IT766_RS12170	COG2177	Part of the ABC transporter FtsEX involved in
IT766_RS12175	COG2884	Cell division ATP-binding protein ftsE
IT766_RS12180	COG0552	protein localization to endoplasmic reticulum
IT766_RS12185	COG0742	ribosomal rna small subunit methyltransferase
IT766_RS12215	COG0783	Belongs to the Dps family
IT766_RS12220	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IT766_RS12225	COG1280	lysine exporter protein (LysE YggA)
IT766_RS12230	COG2267	carboxylic ester hydrolase activity
IT766_RS12235	COG0561	phosphatase activity
IT766_RS12250	COG3287	FIST C domain
IT766_RS12250	COG2200	EAL domain
IT766_RS12250	COG2199	diguanylate cyclase activity
IT766_RS12255	COG1011	Hydrolase
IT766_RS12260	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IT766_RS12270	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IT766_RS12275	COG0019	diaminopimelate decarboxylase activity
IT766_RS12285	COG1965	Belongs to the frataxin family
IT766_RS12295	COG0181	hydroxymethylbilane synthase activity
IT766_RS12300	COG1587	Uroporphyrinogen-III synthase
IT766_RS12305	COG2959	enzyme of heme biosynthesis
IT766_RS12310	COG3071	HemY protein
IT766_RS12325	COG3078	GTPase activator activity
IT766_RS12345	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IT766_RS12345	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IT766_RS12360	COG0084	hydrolase, TatD family'
IT766_RS12365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IT766_RS12375	COG0840	transmembrane signaling receptor activity
IT766_RS12380	COG1580	Controls the rotational direction of flagella during chemotaxis
IT766_RS12385	COG3161	chorismate lyase activity
IT766_RS12390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IT766_RS12400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IT766_RS12410	COG0534	Mate efflux family protein
IT766_RS12415	COG1858	cytochrome C peroxidase
IT766_RS12420	COG0805	protein transport
IT766_RS12425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IT766_RS12430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IT766_RS12445	COG2226	methyltransferase
IT766_RS12450	COG1322	Protein conserved in bacteria
IT766_RS12460	COG2081	HI0933 family
IT766_RS12470	COG1528	Iron-storage protein
IT766_RS12475	COG0589	response to stress
IT766_RS12495	COG5002	protein histidine kinase activity
IT766_RS12495	COG5001	Diguanylate cyclase
IT766_RS12500	COG1522	sequence-specific DNA binding
IT766_RS12520	COG0006	proline dipeptidase activity
IT766_RS12520	COG0006	proline dipeptidase activity
IT766_RS12525	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IT766_RS12530	COG2022	thiamine diphosphate biosynthetic process
IT766_RS12535	COG2104	thiamine diphosphate biosynthetic process
IT766_RS12540	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IT766_RS12550	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IT766_RS12555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IT766_RS12595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IT766_RS12605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IT766_RS12610	COG0408	coproporphyrinogen oxidase activity
IT766_RS12615	COG0009	L-threonylcarbamoyladenylate synthase
IT766_RS12620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IT766_RS12625	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IT766_RS12630	COG0551	DNA topoisomerase type I activity
IT766_RS12635	COG2922	Belongs to the Smg family
IT766_RS12640	COG0758	DNA mediated transformation
IT766_RS12645	COG1652	LysM domain
IT766_RS12650	COG0242	peptide deformylase activity
IT766_RS12655	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IT766_RS12660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IT766_RS12660	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IT766_RS12665	COG0569	domain protein
IT766_RS12670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IT766_RS12680	COG1272	protein, Hemolysin III
IT766_RS12685	COG4326	sporulation control protein
IT766_RS12690	COG3084	Protein conserved in bacteria
IT766_RS12700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IT766_RS12705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IT766_RS12710	COG0204	Acyl-transferase
IT766_RS12715	COG0606	chelatase, subunit chli
IT766_RS12730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IT766_RS12735	COG0129	dihydroxy-acid dehydratase activity
IT766_RS12745	COG0604	alcohol dehydrogenase
IT766_RS12755	COG0425	Belongs to the sulfur carrier protein TusA family
IT766_RS12765	COG2119	membrane
IT766_RS12770	COG0752	glycyl-tRNA synthetase alpha subunit
IT766_RS12775	COG0751	glycine-tRNA ligase activity
IT766_RS12780	COG3977	Valine--pyruvate aminotransferase
IT766_RS12785	COG0071	Belongs to the small heat shock protein (HSP20) family
IT766_RS12795	COG0187	DNA topoisomerase II activity
IT766_RS12800	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IT766_RS12805	COG0592	DNA-directed DNA polymerase activity
IT766_RS12810	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IT766_RS12825	COG1126	abc transporter atp-binding protein
IT766_RS12830	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IT766_RS12835	COG0594	ribonuclease P activity
IT766_RS12845	COG0706	membrane insertase activity
IT766_RS12850	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IT766_RS12855	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IT766_RS12860	COG0445	tRNA wobble uridine modification
IT766_RS12870	COG1192	Involved in chromosome partitioning
IT766_RS12875	COG1475	DNA binding
IT766_RS12880	COG3312	ion transport
IT766_RS12885	COG0356	it plays a direct role in the translocation of protons across the membrane
IT766_RS12895	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IT766_RS12900	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IT766_RS12905	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IT766_RS12910	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IT766_RS12915	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IT766_RS12920	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IT766_RS12925	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IT766_RS12930	COG2814	Major facilitator Superfamily
IT766_RS12935	COG0583	DNA-binding transcription factor activity
IT766_RS12940	COG0183	Belongs to the thiolase family
IT766_RS12950	COG1739	Uncharacterized protein family UPF0029
IT766_RS12955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IT766_RS12960	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
IT766_RS13005	COG0583	DNA-binding transcription factor activity
IT766_RS13010	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IT766_RS13015	COG2960	long-chain fatty acid transporting porin activity
IT766_RS13020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IT766_RS13025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IT766_RS13030	COG1309	transcriptional regulator
IT766_RS13080	COG0747	negative chemotaxis
IT766_RS13085	COG0601	transmembrane transport
IT766_RS13090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IT766_RS13100	COG2131	deaminase
IT766_RS13125	COG3621	Patatin-like phospholipase
IT766_RS13175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IT766_RS13180	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IT766_RS13190	COG0210	DNA helicase
IT766_RS13195	COG1280	lysine exporter protein (LysE YggA)
IT766_RS13210	COG2962	Rard protein
IT766_RS13215	COG0514	ATP-dependent DNA helicase (RecQ)
IT766_RS13230	COG1132	(ABC) transporter
IT766_RS13235	COG4774	siderophore transport
IT766_RS13240	COG1120	ATPase activity
IT766_RS13260	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IT766_RS13265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT766_RS13265	COG1263	PTS System
IT766_RS13270	COG2862	Uncharacterized protein family, UPF0114
IT766_RS13275	COG1561	YicC-like family, N-terminal region
IT766_RS13280	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IT766_RS13285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IT766_RS13290	COG1560	Kdo2-lipid A biosynthetic process
IT766_RS13295	COG1560	Kdo2-lipid A biosynthetic process
IT766_RS13300	COG1309	transcriptional regulator
IT766_RS13310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IT766_RS13320	COG2003	Belongs to the UPF0758 family
IT766_RS13325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IT766_RS13330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IT766_RS13340	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IT766_RS13345	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IT766_RS13350	COG0859	PFAM glycosyl transferase family 9
IT766_RS13355	COG0463	Glycosyl transferase, family 2
IT766_RS13360	COG0859	PFAM glycosyl transferase family 9
IT766_RS13365	COG3642	lipopolysaccharide core region biosynthetic process
IT766_RS13395	COG1519	Transferase
IT766_RS13430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IT766_RS13435	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IT766_RS13435	COG0662	Cupin 2, conserved barrel domain protein
IT766_RS13440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IT766_RS13445	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IT766_RS13475	COG0318	PFAM AMP-dependent synthetase and ligase
IT766_RS13480	COG1012	belongs to the aldehyde dehydrogenase family
IT766_RS13480	COG1454	alcohol dehydrogenase
IT766_RS13525	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IT766_RS13530	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IT766_RS13535	COG0668	transmembrane transport
IT766_RS13540	COG1573	uracil-dna glycosylase
IT766_RS13550	COG3068	Protein conserved in bacteria
IT766_RS13560	COG1940	carbohydrate kinase activity
IT766_RS13565	COG1253	flavin adenine dinucleotide binding
IT766_RS13570	COG0776	regulation of translation
IT766_RS13580	COG0151	Belongs to the GarS family
IT766_RS13595	COG0789	Transcriptional regulator
IT766_RS13600	COG3710	Transcriptional regulator
IT766_RS13605	COG0531	amino acid
IT766_RS13610	COG1982	Orn Lys Arg decarboxylase major
IT766_RS13615	COG0840	transmembrane signaling receptor activity
IT766_RS13630	COG0800	Aldolase
IT766_RS13640	COG3265	gluconokinase activity
IT766_RS13645	COG0129	dihydroxy-acid dehydratase activity
IT766_RS13650	COG1609	Transcriptional regulator
IT766_RS13655	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IT766_RS13660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IT766_RS13665	COG2264	protein methyltransferase activity
IT766_RS13670	COG0439	Biotin carboxylase
IT766_RS13675	COG0511	ligase activity, forming carbon-carbon bonds
IT766_RS13680	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IT766_RS13685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IT766_RS13700	COG2814	Major facilitator Superfamily
IT766_RS13705	COG0784	Response regulator, receiver
IT766_RS13705	COG2205	protein histidine kinase activity
IT766_RS13710	COG0248	Ppx GppA phosphatase
IT766_RS13715	COG0513	Belongs to the DEAD box helicase family
IT766_RS13720	COG3118	belongs to the thioredoxin family
IT766_RS13735	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IT766_RS13750	COG2910	NAD(P)H-binding
IT766_RS13760	COG0840	transmembrane signaling receptor activity
IT766_RS13765	COG4221	oxidoreductase activity
IT766_RS13775	COG1901	pseudouridine methyltransferase
IT766_RS13790	COG0531	amino acid
IT766_RS13795	COG1982	Orn Lys Arg decarboxylase major
IT766_RS13825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IT766_RS13850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IT766_RS13890	COG0745	RESPONSE REGULATOR receiver
IT766_RS13915	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IT766_RS13920	COG0840	transmembrane signaling receptor activity
IT766_RS13925	COG0835	chemotaxis
IT766_RS13930	COG0835	chemotaxis
IT766_RS13935	COG0643	Histidine kinase
IT766_RS13935	COG2198	Histidine kinase
IT766_RS13955	COG0601	transmembrane transport
IT766_RS13960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IT766_RS13970	COG2194	sulfuric ester hydrolase activity
IT766_RS13975	COG0642	Histidine kinase
IT766_RS14010	COG1444	tRNA N-acetyltransferase activity
IT766_RS14015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IT766_RS14050	COG0217	transcriptional regulatory protein
IT766_RS14055	COG2084	Dehydrogenase
IT766_RS14070	COG2909	trisaccharide binding
IT766_RS14075	COG0058	SHG alpha-glucan phosphorylase activity
IT766_RS14080	COG1640	4-alpha-glucanotransferase
IT766_RS14085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IT766_RS14095	COG3501	Rhs element vgr protein
IT766_RS14100	COG4104	PAAR repeat-containing protein
IT766_RS14130	COG0471	metal ion transport
IT766_RS14135	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IT766_RS14175	COG0671	phosphoesterase, PA-phosphatase related
IT766_RS14180	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IT766_RS14190	COG1999	signal sequence binding
IT766_RS14205	COG0786	glutamate:sodium symporter activity
IT766_RS14225	COG1566	PFAM secretion protein HlyD family protein
IT766_RS14250	COG0813	purine-nucleoside phosphorylase activity
IT766_RS14255	COG3272	Protein of unknown function (DUF1722)
IT766_RS14265	COG0415	Belongs to the DNA photolyase family
IT766_RS14270	COG1388	LysM domain
IT766_RS14270	COG1376	ErfK ybiS ycfS ynhG family protein
IT766_RS14280	COG0513	Belongs to the DEAD box helicase family
IT766_RS14285	COG1770	oligopeptidase
IT766_RS14315	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IT766_RS14320	COG0573	inorganic phosphate transmembrane transporter activity
IT766_RS14325	COG0581	inorganic phosphate transmembrane transporter activity
IT766_RS14330	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IT766_RS14345	COG3314	Sporulation integral membrane protein YlbJ
IT766_RS14350	COG0659	secondary active sulfate transmembrane transporter activity
IT766_RS14360	COG0739	heme binding
IT766_RS14365	COG3300	MHYT domain
IT766_RS14365	COG5001	Diguanylate cyclase
IT766_RS14370	COG0583	DNA-binding transcription factor activity
IT766_RS14375	COG2814	Major facilitator Superfamily
IT766_RS14395	COG1301	dicarboxylic acid transport
IT766_RS14405	COG1342	Belongs to the UPF0251 family
IT766_RS14435	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IT766_RS14440	COG0673	inositol 2-dehydrogenase activity
IT766_RS14450	COG2771	luxR family
IT766_RS14450	COG2200	EAL domain
IT766_RS14455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IT766_RS14465	COG0564	pseudouridine synthase activity
IT766_RS14530	COG3829	transcription factor binding
IT766_RS14555	COG3409	Peptidoglycan-binding domain 1 protein
IT766_RS14555	COG3501	Rhs element vgr protein
IT766_RS14570	COG1869	D-ribose catabolic process
IT766_RS14575	COG1129	ABC transporter
IT766_RS14580	COG1172	Belongs to the binding-protein-dependent transport system permease family
IT766_RS14585	COG1879	ABC-type sugar transport system periplasmic component
IT766_RS14590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IT766_RS14595	COG1609	Transcriptional regulator
IT766_RS14605	COG3201	nicotinamide mononucleotide transporter
IT766_RS14610	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
IT766_RS14620	COG0584	glycerophosphoryl diester phosphodiesterase
IT766_RS14625	COG2271	Major facilitator Superfamily
IT766_RS14660	COG0579	oxidoreductase
IT766_RS14670	COG0242	peptide deformylase activity
IT766_RS14680	COG1320	monovalent cation:proton antiporter activity
IT766_RS14685	COG2212	antiporter activity
IT766_RS14690	COG1863	multisubunit Na H antiporter MnhE subunit
IT766_RS14695	COG0651	ATP synthesis coupled electron transport
IT766_RS14700	COG1006	Multisubunit Na H antiporter MnhC subunit
IT766_RS14705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IT766_RS14705	COG2111	Na H antiporter
IT766_RS14715	COG0589	response to stress
IT766_RS14720	COG0814	amino acid
IT766_RS14735	COG3530	Putative quorum-sensing-regulated virulence factor
IT766_RS14745	COG5001	Diguanylate cyclase
IT766_RS14745	COG5002	protein histidine kinase activity
IT766_RS14750	COG1278	Cold shock
IT766_RS14765	COG2304	oxidoreductase activity
IT766_RS14785	COG0714	Associated with various cellular activities
IT766_RS14790	COG0840	transmembrane signaling receptor activity
IT766_RS14805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IT766_RS14810	COG2195	Cleaves the N-terminal amino acid of tripeptides
IT766_RS14820	COG3604	Transcriptional regulator
IT766_RS14825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IT766_RS14825	COG1017	nitric oxide dioxygenase activity
IT766_RS14830	COG1278	Cold shock
IT766_RS14835	COG3036	rescue of stalled ribosome
IT766_RS14860	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IT766_RS14860	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IT766_RS14865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IT766_RS14875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IT766_RS14885	COG0516	GMP reductase activity
IT766_RS14920	COG0513	Belongs to the DEAD box helicase family
IT766_RS14925	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IT766_RS14930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IT766_RS14935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IT766_RS14945	COG4191	Histidine kinase
IT766_RS14945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IT766_RS14955	COG1757	Na H antiporter
IT766_RS14960	COG2814	Major facilitator Superfamily
IT766_RS14970	COG3706	GGDEF domain
IT766_RS14975	COG3240	lipase activity
IT766_RS14985	COG0840	transmembrane signaling receptor activity
IT766_RS14990	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IT766_RS14995	COG5380	lipid catabolic process
IT766_RS15025	COG4605	iron ion homeostasis
IT766_RS15030	COG4604	ABC transporter, ATP-binding protein
IT766_RS15035	COG2207	Transcriptional regulator
IT766_RS15050	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IT766_RS15070	COG0745	RESPONSE REGULATOR receiver
IT766_RS15080	COG3623	hexulose-6-phosphate isomerase
IT766_RS15085	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IT766_RS15090	COG0561	phosphatase activity
IT766_RS15120	COG3038	cytochrome b561
IT766_RS15125	COG0366	Alpha amylase catalytic
IT766_RS15150	COG0745	RESPONSE REGULATOR receiver
IT766_RS15155	COG5002	protein histidine kinase activity
IT766_RS15180	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IT766_RS15195	COG2814	Major facilitator Superfamily
IT766_RS15210	COG1686	Belongs to the peptidase S11 family
IT766_RS15235	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IT766_RS15235	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IT766_RS15240	COG0509	glycine decarboxylation via glycine cleavage system
IT766_RS15245	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IT766_RS15255	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IT766_RS15265	COG3039	Transposase
IT766_RS15300	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IT766_RS15305	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IT766_RS15355	COG1028	Short-chain dehydrogenase reductase Sdr
IT766_RS15390	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IT766_RS15415	COG0494	nUDIX hydrolase
IT766_RS15430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IT766_RS15435	COG3040	lipid binding
IT766_RS15465	COG3041	Addiction module toxin RelE StbE family
IT766_RS15560	COG1619	proteins homologs of microcin C7 resistance protein MccF
IT766_RS15610	COG0346	lactoylglutathione lyase activity
IT766_RS15625	COG3040	lipid binding
IT766_RS15640	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IT766_RS15650	COG1280	lysine exporter protein (LysE YggA)
IT766_RS15835	COG3549	Plasmid maintenance system killer
IT766_RS15840	COG3093	addiction module antidote protein HigA
IT766_RS15860	COG0384	phenazine biosynthesis protein PhzF
IT766_RS15890	COG0346	lactoylglutathione lyase activity
IT766_RS15910	COG3040	lipid binding
IT766_RS15965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IT766_RS16060	COG1619	proteins homologs of microcin C7 resistance protein MccF
IT766_RS16085	COG3040	lipid binding
IT766_RS16140	COG4977	sequence-specific DNA binding
IT766_RS16220	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
IT766_RS16225	COG2944	sequence-specific DNA binding
IT766_RS16240	COG3039	Transposase
IT766_RS16265	COG0346	lactoylglutathione lyase activity
IT766_RS16410	COG0346	lactoylglutathione lyase activity
IT766_RS16425	COG1328	CTP reductase activity
IT766_RS16430	COG0602	queuosine metabolic process
IT766_RS16440	COG4067	protein conserved in archaea
IT766_RS16440	COG0189	ligase activity
IT766_RS16445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT766_RS16445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IT766_RS16445	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IT766_RS16450	COG1105	Belongs to the carbohydrate kinase PfkB family
IT766_RS16455	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IT766_RS16455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IT766_RS16460	COG1609	Transcriptional regulator
IT766_RS16465	COG0420	3'-5' exonuclease activity
IT766_RS16470	COG0419	ATPase involved in DNA repair
IT766_RS16480	COG0156	8-amino-7-oxononanoate synthase activity
IT766_RS16495	COG0523	cobalamin synthesis protein
IT766_RS16510	COG0674	pyruvate-flavodoxin oxidoreductase activity
IT766_RS16510	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IT766_RS16510	COG1013	pyruvate-flavodoxin oxidoreductase activity
IT766_RS16510	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IT766_RS16515	COG2205	protein histidine kinase activity
IT766_RS16520	COG0745	RESPONSE REGULATOR receiver
IT766_RS16525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IT766_RS16530	COG0586	Pfam SNARE associated Golgi protein
IT766_RS16540	COG2200	EAL domain
IT766_RS16550	COG3038	cytochrome b561
IT766_RS16560	COG2116	formate transmembrane transporter activity
IT766_RS16565	COG0583	DNA-binding transcription factor activity
IT766_RS16575	COG3593	DNA synthesis involved in DNA repair
IT766_RS16580	COG0737	Belongs to the 5'-nucleotidase family
IT766_RS16595	COG2824	Alkylphosphonate utilization operon protein PhnA
IT766_RS16625	COG2199	diguanylate cyclase activity
IT766_RS16645	COG3706	GGDEF domain
IT766_RS16660	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IT766_RS16665	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IT766_RS16675	COG0745	RESPONSE REGULATOR receiver
IT766_RS16690	COG3140	Belongs to the UPF0181 family
IT766_RS16695	COG0023	Translation Initiation Factor
IT766_RS16715	COG0045	succinate-CoA ligase (ADP-forming) activity
IT766_RS16715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IT766_RS16715	COG1042	CoA-binding domain protein
IT766_RS16720	COG0583	DNA-binding transcription factor activity
IT766_RS16740	COG2050	protein possibly involved in aromatic compounds catabolism
IT766_RS16760	COG0625	glutathione transferase activity
IT766_RS16775	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IT766_RS16780	COG4172	Belongs to the ABC transporter superfamily
IT766_RS16785	COG4239	(ABC) transporter, permease
IT766_RS16790	COG4174	ABC transporter (Permease)
IT766_RS16795	COG4166	transmembrane transport
IT766_RS16820	COG3104	oligopeptide transport
IT766_RS16840	COG3842	ATPase activity
IT766_RS16850	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IT766_RS16855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IT766_RS16860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IT766_RS16865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IT766_RS16870	COG1011	Hydrolase
IT766_RS16880	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IT766_RS16885	COG1970	mechanosensitive ion channel activity
IT766_RS16890	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IT766_RS16895	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IT766_RS16895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IT766_RS16900	COG0302	gtp cyclohydrolase
IT766_RS16910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IT766_RS16920	COG2897	thiosulfate sulfurtransferase activity
IT766_RS16925	COG2390	Transcriptional regulator
IT766_RS16935	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IT766_RS16960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IT766_RS16985	COG0583	DNA-binding transcription factor activity
IT766_RS16990	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IT766_RS17030	COG0446	pyridine nucleotide-disulphide oxidoreductase
IT766_RS17075	COG1263	PTS System
IT766_RS17075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IT766_RS17080	COG1609	Transcriptional regulator
IT766_RS17085	COG1621	beta-fructofuranosidase activity
IT766_RS17090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IT766_RS17095	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IT766_RS17105	COG2885	chlorophyll binding
IT766_RS17110	COG0545	Peptidyl-prolyl cis-trans isomerase
IT766_RS17115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IT766_RS17120	COG0840	transmembrane signaling receptor activity
IT766_RS17125	COG3069	C4-dicarboxylate transmembrane transporter activity
IT766_RS17130	COG1760	l-serine dehydratase
IT766_RS17150	COG1609	Transcriptional regulator
IT766_RS17155	COG2197	response regulator
IT766_RS17160	COG3850	Histidine kinase
IT766_RS17165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IT766_RS17175	COG0243	molybdopterin cofactor binding
IT766_RS17195	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IT766_RS17200	COG2197	response regulator
IT766_RS17205	COG3851	Histidine kinase
IT766_RS17210	COG2271	Major facilitator Superfamily
IT766_RS17215	COG1840	ABC-type Fe3 transport system, periplasmic component
IT766_RS17225	COG3842	ATPase activity
IT766_RS17230	COG3243	poly(R)-hydroxyalkanoic acid synthase
IT766_RS17240	COG0183	Belongs to the thiolase family
IT766_RS17250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IT766_RS17255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IT766_RS17275	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IT766_RS17285	COG1979	alcohol dehydrogenase
IT766_RS17300	COG4191	Histidine kinase
IT766_RS17310	COG2271	Major facilitator Superfamily
IT766_RS17315	COG0469	pyruvate kinase activity
IT766_RS17320	COG0784	Response regulator, receiver
IT766_RS17320	COG2205	protein histidine kinase activity
IT766_RS17320	COG2198	Histidine kinase
IT766_RS17325	COG1879	ABC-type sugar transport system periplasmic component
IT766_RS17330	COG1803	Methylglyoxal synthase
IT766_RS17335	COG1335	isochorismatase
IT766_RS17340	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IT766_RS17355	COG0210	DNA helicase
IT766_RS17360	COG1289	transmembrane transporter activity
IT766_RS17390	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IT766_RS17395	COG4149	molybdate abc transporter
IT766_RS17400	COG0725	ABC transporter, periplasmic molybdate-binding protein
IT766_RS17405	COG1492	cobalamin metabolic process
IT766_RS17445	COG0784	Response regulator, receiver
IT766_RS17445	COG5002	protein histidine kinase activity
IT766_RS17450	COG1879	ABC-type sugar transport system periplasmic component
IT766_RS17460	COG2827	Endonuclease containing a URI domain
IT766_RS17475	COG2926	Belongs to the UPF0265 family
IT766_RS17485	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IT766_RS17490	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IT766_RS17495	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IT766_RS17500	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
IT766_RS17505	COG0247	lactate metabolic process
IT766_RS17510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IT766_RS17515	COG3118	belongs to the thioredoxin family
IT766_RS17545	COG0583	DNA-binding transcription factor activity
IT766_RS17550	COG4160	amino acid transport
IT766_RS17555	COG4215	(ABC) transporter
IT766_RS17560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IT766_RS17565	COG1126	abc transporter atp-binding protein
IT766_RS17575	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IT766_RS17585	COG0494	nUDIX hydrolase
IT766_RS17590	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IT766_RS17600	COG1309	transcriptional regulator
IT766_RS17605	COG0513	Belongs to the DEAD box helicase family
IT766_RS17610	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
IT766_RS17615	COG0814	amino acid
IT766_RS17620	COG0840	transmembrane signaling receptor activity
IT766_RS17625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IT766_RS17630	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IT766_RS17640	COG1984	allophanate hydrolase subunit 2
IT766_RS17655	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IT766_RS17660	COG4181	ATPase activity
IT766_RS17670	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IT766_RS17675	COG1716	ATPase activity
IT766_RS17675	COG5001	Diguanylate cyclase
IT766_RS17685	COG0484	heat shock protein binding
IT766_RS17725	COG0546	phosphoglycolate phosphatase activity
IT766_RS17740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IT766_RS17745	COG1368	sulfuric ester hydrolase activity
IT766_RS17755	COG0513	Belongs to the DEAD box helicase family
IT766_RS17770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IT766_RS17780	COG3046	protein related to deoxyribodipyrimidine photolyase
IT766_RS17785	COG3397	chitin binding
IT766_RS17790	COG3227	Zinc metalloprotease (Elastase)
IT766_RS17800	COG0010	Belongs to the arginase family
IT766_RS17805	COG1166	arginine decarboxylase activity
IT766_RS17815	COG2239	Acts as a magnesium transporter
IT766_RS17820	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IT766_RS17825	COG0459	protein refolding
IT766_RS17835	COG0527	aspartate kinase activity
IT766_RS17840	COG0662	Cupin 2, conserved barrel domain protein
IT766_RS17845	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IT766_RS17850	COG0456	acetyltransferase
IT766_RS17860	COG3186	Phenylalanine-4-hydroxylase
IT766_RS17865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IT766_RS17880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IT766_RS17905	COG1253	flavin adenine dinucleotide binding
IT766_RS17910	COG1765	OsmC-like protein
IT766_RS17935	COG0531	amino acid
IT766_RS17950	COG3279	Response regulator of the LytR AlgR family
IT766_RS17955	COG3275	phosphorelay sensor kinase activity
IT766_RS17970	COG1136	(ABC) transporter
IT766_RS17970	COG0577	efflux transmembrane transporter activity
IT766_RS17975	COG1136	(ABC) transporter
IT766_RS17985	COG4989	oxidoreductase activity
IT766_RS17990	COG0366	Alpha amylase catalytic
IT766_RS18000	COG2067	long-chain fatty acid transport protein
IT766_RS18005	COG2267	carboxylic ester hydrolase activity
IT766_RS18015	COG3227	Zinc metalloprotease (Elastase)
IT766_RS18025	COG3047	cAMP biosynthetic process
IT766_RS18035	COG1686	Belongs to the peptidase S11 family
IT766_RS18040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IT766_RS18045	COG1271	oxidase subunit
IT766_RS18050	COG1294	oxidase, subunit
IT766_RS18065	COG3048	D-serine ammonia-lyase activity
IT766_RS18070	COG0583	DNA-binding transcription factor activity
IT766_RS18115	COG1063	alcohol dehydrogenase
IT766_RS18140	COG0346	lactoylglutathione lyase activity
IT766_RS18160	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IT766_RS18165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IT766_RS18170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IT766_RS18175	COG0363	glucosamine-6-phosphate deaminase activity
IT766_RS18180	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IT766_RS18205	COG1929	Belongs to the glycerate kinase type-1 family
IT766_RS18210	COG2610	gluconate transmembrane transporter activity
IT766_RS18215	COG3835	regulator
IT766_RS18225	COG0748	coenzyme F420 binding
IT766_RS18230	COG3721	Heme iron utilization protein
IT766_RS18240	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IT766_RS18245	COG0811	peptide transport
IT766_RS18250	COG0848	biopolymer transport protein
IT766_RS18255	COG4558	Periplasmic binding protein
IT766_RS18260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IT766_RS18300	COG0633	Ferredoxin
IT766_RS18300	COG3217	Mosc domain protein beta barrel domain protein
IT766_RS18300	COG0633	Ferredoxin
IT766_RS18300	COG3217	Mosc domain protein beta barrel domain protein
IT766_RS18305	COG0418	dihydroorotase activity
IT766_RS18315	COG3152	Membrane
IT766_RS18325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IT766_RS18330	COG2354	Protein conserved in bacteria
IT766_RS18335	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IT766_RS18340	COG1278	Cold shock
IT766_RS18365	COG2199	diguanylate cyclase activity
IT766_RS18370	COG1349	DNA-binding transcription factor activity
IT766_RS18385	COG3833	ABC-type maltose transport systems, permease component
IT766_RS18390	COG1175	transmembrane transport
IT766_RS18400	COG3842	ATPase activity
IT766_RS18405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IT766_RS18420	COG0393	Putative heavy-metal-binding
IT766_RS18430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IT766_RS18435	COG0784	Response regulator, receiver
IT766_RS18435	COG0835	chemotaxis
IT766_RS18440	COG1846	Transcriptional regulator
IT766_RS18445	COG3706	GGDEF domain
IT766_RS18480	COG0583	DNA-binding transcription factor activity
IT766_RS18485	COG5001	Diguanylate cyclase
IT766_RS18495	COG1741	Belongs to the pirin family
IT766_RS18500	COG3123	guanosine phosphorylase activity
IT766_RS18510	COG2211	Major facilitator Superfamily
IT766_RS18515	COG0840	transmembrane signaling receptor activity
IT766_RS18520	COG1067	ATP-dependent peptidase activity
IT766_RS18530	COG4172	Belongs to the ABC transporter superfamily
IT766_RS18555	COG0583	DNA-binding transcription factor activity
IT766_RS18565	COG1620	l-lactate permease
IT766_RS18580	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IT766_RS18590	COG0840	transmembrane signaling receptor activity
IT766_RS18600	COG0513	Belongs to the DEAD box helicase family
IT766_RS18605	COG0583	DNA-binding transcription factor activity
IT766_RS18615	COG1902	pentaerythritol trinitrate reductase activity
IT766_RS18625	COG1132	(ABC) transporter
IT766_RS18635	COG1902	pentaerythritol trinitrate reductase activity
IT766_RS18645	COG1280	lysine exporter protein (LysE YggA)
IT766_RS18650	COG2207	Transcriptional regulator
IT766_RS18670	COG1846	Transcriptional regulator
IT766_RS18675	COG1764	response to oxidative stress
IT766_RS18680	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IT766_RS18685	COG0697	spore germination
IT766_RS18695	COG0700	Nucleoside recognition
IT766_RS18700	COG3366	ferrous iron transmembrane transporter activity
IT766_RS18705	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IT766_RS18715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IT766_RS18720	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IT766_RS18725	COG2259	Doxx family
IT766_RS18750	COG0363	glucosamine-6-phosphate deaminase activity
IT766_RS18765	COG4580	involved in the transport of maltose and maltodextrins
IT766_RS18780	COG0840	transmembrane signaling receptor activity
IT766_RS18795	COG0840	transmembrane signaling receptor activity
IT766_RS18805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IT766_RS18810	COG1126	abc transporter atp-binding protein
IT766_RS18820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IT766_RS18825	COG4597	amino acid ABC transporter
IT766_RS18830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IT766_RS18840	COG0739	heme binding
IT766_RS18845	COG2213	PTS system mannitol-specific
IT766_RS18845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IT766_RS18850	COG0246	Mannitol dehydrogenase
IT766_RS18855	COG3722	fumarate hydratase activity
IT766_RS18860	COG0673	inositol 2-dehydrogenase activity