locus-tag	class	description
ASZ87_RS00030	COG0488	(ABC) transporter
ASZ87_RS00075	COG3941	tape measure
ASZ87_RS00115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASZ87_RS00125	COG0582	viral genome integration into host DNA
ASZ87_RS00140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ87_RS00150	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASZ87_RS00150	COG3008	intermembrane lipid transfer
ASZ87_RS00155	COG2995	paraquat-inducible protein a
ASZ87_RS00160	COG0668	transmembrane transport
ASZ87_RS00185	COG1309	transcriptional regulator
ASZ87_RS00190	COG1012	belongs to the aldehyde dehydrogenase family
ASZ87_RS00215	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASZ87_RS00225	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASZ87_RS00255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASZ87_RS00260	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ASZ87_RS00265	COG0297	glycogen (starch) synthase activity
ASZ87_RS00285	COG3070	regulator of competence-specific genes
ASZ87_RS00290	COG1609	Transcriptional regulator
ASZ87_RS00300	COG3381	protein complex oligomerization
ASZ87_RS00305	COG0745	RESPONSE REGULATOR receiver
ASZ87_RS00310	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ASZ87_RS00315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASZ87_RS00325	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ASZ87_RS00345	COG1032	radical SAM domain protein
ASZ87_RS00350	COG5001	Diguanylate cyclase
ASZ87_RS00355	COG0612	Peptidase, M16
ASZ87_RS00370	COG0583	DNA-binding transcription factor activity
ASZ87_RS00375	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASZ87_RS00385	COG2350	Protein conserved in bacteria
ASZ87_RS00390	COG1607	acyl-coa hydrolase
ASZ87_RS00405	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ASZ87_RS00410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASZ87_RS00425	COG2116	formate transmembrane transporter activity
ASZ87_RS00435	COG4459	periplasmic nitrate reductase
ASZ87_RS00440	COG3005	denitrification pathway
ASZ87_RS00445	COG0243	molybdopterin cofactor binding
ASZ87_RS00465	COG1227	inorganic diphosphatase activity
ASZ87_RS00480	COG4172	Belongs to the ABC transporter superfamily
ASZ87_RS00495	COG4168	peptide transport system, permease
ASZ87_RS00505	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ASZ87_RS00510	COG1842	Phage shock protein A
ASZ87_RS00525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ87_RS00540	COG2818	Glycosylase
ASZ87_RS00545	COG0626	cystathionine gamma-synthase activity
ASZ87_RS00560	COG0733	neurotransmitter:sodium symporter activity
ASZ87_RS00565	COG0564	pseudouridine synthase activity
ASZ87_RS00570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASZ87_RS00575	COG4136	ATPase activity
ASZ87_RS00580	COG4135	transport system, permease component
ASZ87_RS00585	COG4134	Bacterial extracellular solute-binding protein
ASZ87_RS00595	COG3313	Fe-S protein
ASZ87_RS00605	COG0842	Transport permease protein
ASZ87_RS00610	COG1131	(ABC) transporter
ASZ87_RS00615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ87_RS00620	COG0814	amino acid
ASZ87_RS00630	COG2239	Acts as a magnesium transporter
ASZ87_RS00635	COG0784	Response regulator, receiver
ASZ87_RS00635	COG2205	protein histidine kinase activity
ASZ87_RS00650	COG4934	collagen metabolic process
ASZ87_RS00680	COG0840	transmembrane signaling receptor activity
ASZ87_RS00695	COG3706	GGDEF domain
ASZ87_RS00695	COG5001	Diguanylate cyclase
ASZ87_RS00695	COG4251	negative regulation of phosphorylation
ASZ87_RS00695	COG2203	Gaf domain
ASZ87_RS00700	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASZ87_RS00720	COG1061	Type III restriction enzyme res subunit
ASZ87_RS00725	COG1187	pseudouridine synthase activity
ASZ87_RS00730	COG2814	Major facilitator Superfamily
ASZ87_RS00740	COG0702	epimerase
ASZ87_RS00745	COG0534	Mate efflux family protein
ASZ87_RS00750	COG4181	ATPase activity
ASZ87_RS00755	COG0577	efflux transmembrane transporter activity
ASZ87_RS00765	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASZ87_RS00780	COG1748	Saccharopine dehydrogenase
ASZ87_RS00795	COG1538	Outer membrane efflux protein
ASZ87_RS00825	COG0583	DNA-binding transcription factor activity
ASZ87_RS00835	COG1451	nucleotide metabolic process
ASZ87_RS00850	COG3063	Type IV pilus biogenesis stability protein PilW
ASZ87_RS00855	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ASZ87_RS00875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ87_RS00890	COG3290	protein histidine kinase activity
ASZ87_RS00895	COG4565	transcriptional regulatory protein
ASZ87_RS00905	COG0835	chemotaxis
ASZ87_RS00905	COG0784	Response regulator, receiver
ASZ87_RS00950	COG1085	galactose-1-phosphate uridylyltransferase
ASZ87_RS00955	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ASZ87_RS00960	COG2017	converts alpha-aldose to the beta-anomer
ASZ87_RS00970	COG2200	EAL domain
ASZ87_RS00970	COG2199	diguanylate cyclase activity
ASZ87_RS00985	COG3527	Alpha-acetolactate decarboxylase
ASZ87_RS01000	COG0753	catalase activity
ASZ87_RS01020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASZ87_RS01030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASZ87_RS01075	COG1271	oxidase subunit
ASZ87_RS01080	COG1294	oxidase, subunit
ASZ87_RS01085	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASZ87_RS01085	COG1136	(ABC) transporter
ASZ87_RS01090	COG1136	(ABC) transporter
ASZ87_RS01090	COG0577	efflux transmembrane transporter activity
ASZ87_RS01095	COG1136	(ABC) transporter
ASZ87_RS01095	COG0577	efflux transmembrane transporter activity
ASZ87_RS01115	COG0583	DNA-binding transcription factor activity
ASZ87_RS01125	COG2723	6-phospho-beta-galactosidase activity
ASZ87_RS01130	COG1609	Transcriptional regulator
ASZ87_RS01135	COG0251	oxidation-reduction process
ASZ87_RS01140	COG2731	YhcH YjgK YiaL family protein
ASZ87_RS01145	COG0584	glycerophosphoryl diester phosphodiesterase
ASZ87_RS01150	COG1349	DNA-binding transcription factor activity
ASZ87_RS01155	COG3842	ATPase activity
ASZ87_RS01160	COG0395	ABC-type sugar transport system, permease component
ASZ87_RS01165	COG1175	transmembrane transport
ASZ87_RS01180	COG0811	peptide transport
ASZ87_RS01185	COG0811	peptide transport
ASZ87_RS01190	COG0848	biopolymer transport protein
ASZ87_RS01195	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ASZ87_RS01210	COG1793	dna ligase
ASZ87_RS01220	COG0534	Mate efflux family protein
ASZ87_RS01230	COG3001	Fructosamine kinase
ASZ87_RS01240	COG0791	NLP P60 protein
ASZ87_RS01245	COG0840	transmembrane signaling receptor activity
ASZ87_RS01255	COG3148	PFAM DTW domain containing protein
ASZ87_RS01260	COG1940	carbohydrate kinase activity
ASZ87_RS01295	COG0746	molybdenum cofactor guanylyltransferase activity
ASZ87_RS01300	COG3842	ATPase activity
ASZ87_RS01305	COG4662	Binding-protein-dependent transport system inner membrane component
ASZ87_RS01315	COG2204	response regulator
ASZ87_RS01320	COG3852	Histidine kinase
ASZ87_RS01325	COG0488	(ABC) transporter
ASZ87_RS01330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ASZ87_RS01360	COG0243	molybdopterin cofactor binding
ASZ87_RS01360	COG3383	formate dehydrogenase (NAD+) activity
ASZ87_RS01365	COG0437	4 iron, 4 sulfur cluster binding
ASZ87_RS01380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ASZ87_RS01385	COG1666	GTP binding
ASZ87_RS01390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASZ87_RS01405	COG2996	Protein conserved in bacteria
ASZ87_RS01415	COG3008	intermembrane lipid transfer
ASZ87_RS01420	COG2995	paraquat-inducible protein a
ASZ87_RS01425	COG1132	(ABC) transporter
ASZ87_RS01430	COG1956	GAF domain-containing protein
ASZ87_RS01435	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
ASZ87_RS01450	COG0308	aminopeptidase N
ASZ87_RS01465	COG0167	dihydroorotate dehydrogenase activity
ASZ87_RS01475	COG0116	Belongs to the methyltransferase superfamily
ASZ87_RS01475	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASZ87_RS01485	COG0488	(ABC) transporter
ASZ87_RS01500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASZ87_RS01505	COG1067	ATP-dependent peptidase activity
ASZ87_RS01510	COG3120	sequence-specific DNA binding
ASZ87_RS01615	COG1476	TRANSCRIPTIONal
ASZ87_RS01645	COG4128	Pfam Zonular occludens toxin
ASZ87_RS01665	COG1476	TRANSCRIPTIONal
ASZ87_RS01690	COG1476	TRANSCRIPTIONal
ASZ87_RS01720	COG4128	Pfam Zonular occludens toxin
ASZ87_RS01735	COG1073	alpha beta
ASZ87_RS01735	COG3064	Membrane
ASZ87_RS01735	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ASZ87_RS01740	COG2994	toxin metabolic process
ASZ87_RS01765	COG0784	Response regulator, receiver
ASZ87_RS01765	COG2205	protein histidine kinase activity
ASZ87_RS01780	COG3278	Belongs to the heme-copper respiratory oxidase family
ASZ87_RS01795	COG2010	Cytochrome c
ASZ87_RS01805	COG2217	Heavy metal translocating P-type atpase
ASZ87_RS01820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASZ87_RS01825	COG0589	response to stress
ASZ87_RS01850	COG3842	ATPase activity
ASZ87_RS01860	COG1177	transmembrane transport
ASZ87_RS01870	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASZ87_RS01885	COG1115	amino acid carrier protein
ASZ87_RS01890	COG1280	lysine exporter protein (LysE YggA)
ASZ87_RS01905	COG3675	Pfam Lipase (class 3)
ASZ87_RS01915	COG3501	Rhs element vgr protein
ASZ87_RS01925	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ASZ87_RS01935	COG2814	Major facilitator Superfamily
ASZ87_RS01940	COG1566	PFAM secretion protein HlyD family protein
ASZ87_RS01945	COG1538	Outer membrane efflux protein
ASZ87_RS01955	COG0513	Belongs to the DEAD box helicase family
ASZ87_RS01965	COG0840	transmembrane signaling receptor activity
ASZ87_RS01970	COG0840	transmembrane signaling receptor activity
ASZ87_RS01970	COG3290	protein histidine kinase activity
ASZ87_RS01975	COG0835	chemotaxis
ASZ87_RS01980	COG2201	protein-glutamate methylesterase activity
ASZ87_RS01990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASZ87_RS01995	COG0643	Histidine kinase
ASZ87_RS01995	COG0784	Response regulator, receiver
ASZ87_RS01995	COG2198	Histidine kinase
ASZ87_RS02000	COG2198	Histidine kinase
ASZ87_RS02000	COG0643	Histidine kinase
ASZ87_RS02010	COG0745	RESPONSE REGULATOR receiver
ASZ87_RS02025	COG0415	Belongs to the DNA photolyase family
ASZ87_RS02030	COG0477	Major facilitator Superfamily
ASZ87_RS02035	COG0583	DNA-binding transcription factor activity
ASZ87_RS02045	COG0095	Lipoate-protein ligase
ASZ87_RS02050	COG0443	Heat shock 70 kDa protein
ASZ87_RS02060	COG1643	Atp-dependent helicase
ASZ87_RS02105	COG0443	Heat shock 70 kDa protein
ASZ87_RS02110	COG0443	Heat shock 70 kDa protein
ASZ87_RS02115	COG3706	GGDEF domain
ASZ87_RS02145	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ASZ87_RS02150	COG0602	queuosine metabolic process
ASZ87_RS02155	COG0561	phosphatase activity
ASZ87_RS02165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ87_RS02170	COG4597	amino acid ABC transporter
ASZ87_RS02175	COG0765	amino acid transport
ASZ87_RS02180	COG1126	abc transporter atp-binding protein
ASZ87_RS02185	COG0670	Belongs to the BI1 family
ASZ87_RS02190	COG2920	part of a sulfur-relay system
ASZ87_RS02195	COG1254	Belongs to the acylphosphatase family
ASZ87_RS02200	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASZ87_RS02205	COG3706	GGDEF domain
ASZ87_RS02225	COG3437	response regulator, receiver
ASZ87_RS02230	COG0625	glutathione transferase activity
ASZ87_RS02240	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ASZ87_RS02250	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASZ87_RS02280	COG0372	Belongs to the citrate synthase family
ASZ87_RS02285	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ASZ87_RS02325	COG1129	ABC transporter
ASZ87_RS02360	COG0745	RESPONSE REGULATOR receiver
ASZ87_RS02365	COG2205	protein histidine kinase activity
ASZ87_RS02370	COG3713	MltA-interacting MipA family protein
ASZ87_RS02375	COG2990	Protein conserved in bacteria
ASZ87_RS02385	COG4191	Histidine kinase
ASZ87_RS02385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASZ87_RS02390	COG0471	metal ion transport
ASZ87_RS02400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASZ87_RS02415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ87_RS02425	COG3768	UPF0283 membrane protein
ASZ87_RS02430	COG3106	COG3106 Predicted ATPase
ASZ87_RS02445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASZ87_RS02450	COG0494	nUDIX hydrolase
ASZ87_RS02455	COG0814	amino acid
ASZ87_RS02460	COG1760	l-serine dehydratase
ASZ87_RS02465	COG0720	synthase
ASZ87_RS02470	COG0840	transmembrane signaling receptor activity
ASZ87_RS02475	COG0017	Asparaginyl-tRNA synthetase
ASZ87_RS02480	COG0351	phosphomethylpyrimidine kinase
ASZ87_RS02485	COG3437	response regulator, receiver
ASZ87_RS02485	COG2770	Histidine kinase
ASZ87_RS02495	COG1448	Aminotransferase
ASZ87_RS02510	COG0840	transmembrane signaling receptor activity
ASZ87_RS02515	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ASZ87_RS02520	COG2943	transferase activity, transferring hexosyl groups
ASZ87_RS02525	COG1609	Transcriptional regulator
ASZ87_RS02535	COG1486	melibiose metabolic process
ASZ87_RS02540	COG1447	Phosphotransferase system cellobiose-specific component IIA
ASZ87_RS02550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASZ87_RS02555	COG0726	polysaccharide deacetylase
ASZ87_RS02560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASZ87_RS02565	COG1846	Transcriptional regulator
ASZ87_RS02590	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASZ87_RS02605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASZ87_RS02610	COG3108	Peptidase M15
ASZ87_RS02615	COG2989	Protein conserved in bacteria
ASZ87_RS02640	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASZ87_RS02650	COG2814	Major facilitator Superfamily
ASZ87_RS02660	COG1054	Belongs to the UPF0176 family
ASZ87_RS02670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASZ87_RS02675	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASZ87_RS02680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASZ87_RS02735	COG4139	cobalamin transport
ASZ87_RS02755	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ASZ87_RS02760	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ASZ87_RS02770	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ87_RS02775	COG1823	symporter activity
ASZ87_RS02780	COG2925	Exonuclease
ASZ87_RS02785	COG1380	Effector of murein hydrolase LrgA
ASZ87_RS02790	COG1346	cytolysis
ASZ87_RS02830	COG0776	regulation of translation
ASZ87_RS02835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ87_RS02835	COG0072	phenylalanine-tRNA ligase activity
ASZ87_RS02840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASZ87_RS02880	COG0322	excinuclease ABC activity
ASZ87_RS02885	COG2197	response regulator
ASZ87_RS02890	COG0417	DNA replication proofreading
ASZ87_RS02895	COG5001	Diguanylate cyclase
ASZ87_RS02905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASZ87_RS02910	COG3099	Belongs to the UPF0263 family
ASZ87_RS02925	COG1228	amidohydrolase
ASZ87_RS02930	COG0010	Belongs to the arginase family
ASZ87_RS02935	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ASZ87_RS02940	COG2986	histidine ammonia-lyase
ASZ87_RS02960	COG0247	lactate metabolic process
ASZ87_RS02960	COG0277	FAD linked oxidase domain protein
ASZ87_RS02975	COG2885	chlorophyll binding
ASZ87_RS02995	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASZ87_RS03005	COG0281	malic enzyme
ASZ87_RS03015	COG2949	membrane
ASZ87_RS03020	COG3706	GGDEF domain
ASZ87_RS03025	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASZ87_RS03035	COG0492	ferredoxin-NADP+ reductase activity
ASZ87_RS03040	COG4988	ABC transporter
ASZ87_RS03045	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ASZ87_RS03050	COG1187	pseudouridine synthase activity
ASZ87_RS03055	COG0009	L-threonylcarbamoyladenylate synthase
ASZ87_RS03060	COG0613	PHP domain protein
ASZ87_RS03070	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASZ87_RS03075	COG0512	Glutamine amidotransferase of anthranilate synthase
ASZ87_RS03080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASZ87_RS03085	COG0134	indole-3-glycerol-phosphate synthase activity
ASZ87_RS03085	COG0135	phosphoribosylanthranilate isomerase activity
ASZ87_RS03090	COG0133	tryptophan synthase activity
ASZ87_RS03095	COG0159	tryptophan synthase activity
ASZ87_RS03105	COG1435	thymidine kinase activity
ASZ87_RS03110	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASZ87_RS03115	COG1801	Protein of unknown function DUF72
ASZ87_RS03120	COG4106	trans-aconitate 2-methyltransferase activity
ASZ87_RS03125	COG0500	methyltransferase
ASZ87_RS03130	COG4067	protein conserved in archaea
ASZ87_RS03130	COG0189	ligase activity
ASZ87_RS03145	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ASZ87_RS03155	COG3852	Histidine kinase
ASZ87_RS03170	COG3070	regulator of competence-specific genes
ASZ87_RS03180	COG2431	L-lysine efflux transmembrane transporter activity
ASZ87_RS03190	COG0076	glutamate decarboxylase activity
ASZ87_RS03195	COG1737	Transcriptional regulator
ASZ87_RS03200	COG1012	belongs to the aldehyde dehydrogenase family
ASZ87_RS03200	COG1454	alcohol dehydrogenase
ASZ87_RS03205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASZ87_RS03210	COG2985	domain, Protein
ASZ87_RS03210	COG3273	potassium ion transport
ASZ87_RS03215	COG0542	response to heat
ASZ87_RS03220	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ASZ87_RS03225	COG1278	Cold shock
ASZ87_RS03235	COG1187	pseudouridine synthase activity
ASZ87_RS03240	COG0140	phosphoribosyl-ATP diphosphatase activity
ASZ87_RS03240	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASZ87_RS03245	COG0107	imidazoleglycerol-phosphate synthase activity
ASZ87_RS03250	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ASZ87_RS03255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASZ87_RS03260	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASZ87_RS03260	COG0131	Imidazoleglycerol-phosphate dehydratase
ASZ87_RS03265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASZ87_RS03270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASZ87_RS03275	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ASZ87_RS03280	COG1757	Na H antiporter
ASZ87_RS03285	COG2916	Histone family protein nucleoid-structuring protein H-NS
ASZ87_RS03290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASZ87_RS03295	COG0482	sulfurtransferase activity
ASZ87_RS03300	COG2915	High frequency lysogenization protein hflD homolog
ASZ87_RS03305	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASZ87_RS03315	COG2268	Band 7 protein
ASZ87_RS03325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASZ87_RS03340	COG0300	oxidoreductase activity
ASZ87_RS03350	COG0501	Belongs to the peptidase M48B family
ASZ87_RS03360	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASZ87_RS03365	COG2226	methyltransferase
ASZ87_RS03370	COG0156	8-amino-7-oxononanoate synthase activity
ASZ87_RS03375	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASZ87_RS03380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASZ87_RS03385	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASZ87_RS03390	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASZ87_RS03395	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ASZ87_RS03405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASZ87_RS03410	COG2203	Gaf domain
ASZ87_RS03410	COG2199	diguanylate cyclase activity
ASZ87_RS03420	COG4120	Belongs to the binding-protein-dependent transport system permease family
ASZ87_RS03430	COG4628	conserved protein (DUF2132)
ASZ87_RS03435	COG3092	negative regulation of chromosome organization
ASZ87_RS03440	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASZ87_RS03445	COG0280	phosphate acetyltransferase
ASZ87_RS03445	COG0857	belongs to the CobB CobQ family
ASZ87_RS03450	COG0435	Glutathione S-transferase
ASZ87_RS03455	COG4608	Belongs to the ABC transporter superfamily
ASZ87_RS03460	COG0444	Belongs to the ABC transporter superfamily
ASZ87_RS03465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ87_RS03470	COG0601	transmembrane transport
ASZ87_RS03490	COG2204	response regulator
ASZ87_RS03495	COG3300	MHYT domain
ASZ87_RS03495	COG5001	Diguanylate cyclase
ASZ87_RS03500	COG4191	Histidine kinase
ASZ87_RS03505	COG5002	protein histidine kinase activity
ASZ87_RS03515	COG2201	protein-glutamate methylesterase activity
ASZ87_RS03530	COG0009	L-threonylcarbamoyladenylate synthase
ASZ87_RS03550	COG1881	PFAM PEBP family protein
ASZ87_RS03575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASZ87_RS03580	COG0640	Transcriptional regulator
ASZ87_RS03590	COG3706	GGDEF domain
ASZ87_RS03610	COG1946	Acyl-CoA thioesterase
ASZ87_RS03615	COG1522	sequence-specific DNA binding
ASZ87_RS03625	COG0616	signal peptide processing
ASZ87_RS03630	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ87_RS03635	COG2983	Belongs to the UPF0260 family
ASZ87_RS03645	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASZ87_RS03650	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASZ87_RS03660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ASZ87_RS03665	COG2832	Protein of unknown function (DUF454)
ASZ87_RS03675	COG0745	RESPONSE REGULATOR receiver
ASZ87_RS03680	COG0583	DNA-binding transcription factor activity
ASZ87_RS03685	COG0778	Nitroreductase
ASZ87_RS03690	COG1024	Enoyl-CoA hydratase
ASZ87_RS03690	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASZ87_RS03695	COG0183	Belongs to the thiolase family
ASZ87_RS03715	COG2067	long-chain fatty acid transport protein
ASZ87_RS03725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASZ87_RS03730	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ASZ87_RS03735	COG2982	Protein involved in outer membrane biogenesis
ASZ87_RS03740	COG0572	uridine kinase
ASZ87_RS03750	COG0489	protein tyrosine kinase activity
ASZ87_RS03755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ87_RS03755	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ87_RS03765	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ASZ87_RS03780	COG0517	IMP dehydrogenase activity
ASZ87_RS03780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ASZ87_RS03780	COG0617	tRNA 3'-terminal CCA addition
ASZ87_RS03785	COG2199	diguanylate cyclase activity
ASZ87_RS03790	COG0314	molybdopterin synthase activity
ASZ87_RS03795	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ASZ87_RS03800	COG0315	cyclic pyranopterin monophosphate synthase activity
ASZ87_RS03805	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASZ87_RS03810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ASZ87_RS03815	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ASZ87_RS03820	COG2198	Histidine kinase
ASZ87_RS03825	COG2204	response regulator
ASZ87_RS03835	COG0556	nucleotide-excision repair
ASZ87_RS03845	COG4657	Part of a membrane complex involved in electron transport
ASZ87_RS03850	COG2878	Part of a membrane complex involved in electron transport
ASZ87_RS03855	COG4656	Part of a membrane complex involved in electron transport
ASZ87_RS03875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASZ87_RS03880	COG0346	lactoylglutathione lyase activity
ASZ87_RS03900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASZ87_RS03905	COG2056	Na+-H+ antiporter family
ASZ87_RS03910	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ASZ87_RS03915	COG1286	toxin biosynthetic process
ASZ87_RS03920	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ASZ87_RS03925	COG0285	dihydrofolate synthase activity
ASZ87_RS03930	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ASZ87_RS03935	COG0101	tRNA pseudouridine synthase activity
ASZ87_RS03950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ87_RS03950	COG2190	(PTS) system
ASZ87_RS03950	COG1263	PTS System
ASZ87_RS03955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ASZ87_RS03960	COG1846	Transcriptional regulator
ASZ87_RS03960	COG1940	carbohydrate kinase activity
ASZ87_RS03965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASZ87_RS03965	COG4651	solute:proton antiporter activity
ASZ87_RS03970	COG0367	asparagine synthase
ASZ87_RS03985	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASZ87_RS03990	COG0563	adenylate kinase activity
ASZ87_RS03995	COG0326	Molecular chaperone. Has ATPase activity
ASZ87_RS04000	COG3710	Transcriptional regulator
ASZ87_RS04015	COG0622	Phosphoesterase
ASZ87_RS04020	COG1090	epimerase
ASZ87_RS04025	COG0300	oxidoreductase activity
ASZ87_RS04030	COG3118	belongs to the thioredoxin family
ASZ87_RS04040	COG0330	HflC and HflK could
ASZ87_RS04045	COG1585	Membrane protein implicated in regulation of membrane protease activity
ASZ87_RS04050	COG0789	Transcriptional regulator
ASZ87_RS04065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASZ87_RS04070	COG3115	cell septum assembly
ASZ87_RS04075	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ASZ87_RS04080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASZ87_RS04090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ87_RS04100	COG2190	(PTS) system
ASZ87_RS04105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ87_RS04110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASZ87_RS04115	COG1702	phosphate starvation-inducible protein PhoH
ASZ87_RS04125	COG4535	Mg2 and Co2 transporter CorC
ASZ87_RS04130	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ASZ87_RS04135	COG2888	peptidyl-tyrosine sulfation
ASZ87_RS04140	COG0495	leucyl-tRNA aminoacylation
ASZ87_RS04145	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ASZ87_RS04150	COG1466	dna polymerase III delta subunit
ASZ87_RS04155	COG0799	negative regulation of ribosome biogenesis
ASZ87_RS04160	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ASZ87_RS04165	COG0768	penicillin binding
ASZ87_RS04170	COG0772	Belongs to the SEDS family
ASZ87_RS04175	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASZ87_RS04180	COG1686	Belongs to the peptidase S11 family
ASZ87_RS04185	COG2921	Belongs to the UPF0250 family
ASZ87_RS04190	COG0321	lipoyl(octanoyl) transferase activity
ASZ87_RS04195	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ASZ87_RS04205	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASZ87_RS04230	COG1596	polysaccharide export
ASZ87_RS04240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASZ87_RS04270	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ASZ87_RS04280	COG0438	transferase activity, transferring glycosyl groups
ASZ87_RS04290	COG1045	serine acetyltransferase
ASZ87_RS04310	COG0110	maltose O-acetyltransferase activity
ASZ87_RS04315	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASZ87_RS04320	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASZ87_RS04325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASZ87_RS04330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASZ87_RS04360	COG0366	Alpha amylase catalytic
ASZ87_RS04365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ87_RS04365	COG1263	PTS System
ASZ87_RS04370	COG1609	Transcriptional regulator
ASZ87_RS04375	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASZ87_RS04380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASZ87_RS04385	COG2011	ABC-type metal ion transport system permease component
ASZ87_RS04390	COG1464	Belongs to the NlpA lipoprotein family
ASZ87_RS04395	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
ASZ87_RS04405	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASZ87_RS04405	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASZ87_RS04420	COG1611	Belongs to the LOG family
ASZ87_RS04425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASZ87_RS04430	COG2363	Small membrane protein
ASZ87_RS04435	COG0583	DNA-binding transcription factor activity
ASZ87_RS04445	COG0301	tRNA thio-modification
ASZ87_RS04445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASZ87_RS04455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ASZ87_RS04460	COG1722	exodeoxyribonuclease VII activity
ASZ87_RS04465	COG0142	geranyltranstransferase activity
ASZ87_RS04470	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASZ87_RS04475	COG0564	pseudouridine synthase activity
ASZ87_RS04480	COG3098	single-species biofilm formation
ASZ87_RS04495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASZ87_RS04505	COG1671	Belongs to the UPF0178 family
ASZ87_RS04510	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ASZ87_RS04515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASZ87_RS04520	COG0254	rRNA binding
ASZ87_RS04525	COG1720	tRNA m6t6A37 methyltransferase activity
ASZ87_RS04530	COG0442	prolyl-tRNA aminoacylation
ASZ87_RS04560	COG0047	phosphoribosylformylglycinamidine synthase activity
ASZ87_RS04560	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASZ87_RS04570	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ASZ87_RS04585	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ASZ87_RS04620	COG0484	heat shock protein binding
ASZ87_RS04625	COG0443	Heat shock 70 kDa protein
ASZ87_RS04630	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASZ87_RS04635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASZ87_RS04640	COG0497	DNA recombination
ASZ87_RS04645	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASZ87_RS04650	COG2914	Belongs to the UPF0125 (RnfH) family
ASZ87_RS04655	COG2867	negative regulation of translational initiation
ASZ87_RS04660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASZ87_RS04670	COG0582	viral genome integration into host DNA
ASZ87_RS04685	COG0582	viral genome integration into host DNA
ASZ87_RS04690	COG3064	Membrane
ASZ87_RS04700	COG0739	heme binding
ASZ87_RS04720	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ASZ87_RS04725	COG2207	Transcriptional regulator
ASZ87_RS04735	COG1459	type II secretion system
ASZ87_RS04740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ87_RS04760	COG4796	Type ii and iii secretion system protein
ASZ87_RS04775	COG2165	general secretion pathway protein
ASZ87_RS04785	COG3710	Transcriptional regulator
ASZ87_RS04790	COG0840	transmembrane signaling receptor activity
ASZ87_RS04795	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ASZ87_RS04815	COG1012	belongs to the aldehyde dehydrogenase family
ASZ87_RS04880	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ASZ87_RS04885	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ASZ87_RS04890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASZ87_RS04910	COG3051	citrate lyase alpha subunit
ASZ87_RS04915	COG2301	Belongs to the HpcH HpaI aldolase family
ASZ87_RS04925	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ASZ87_RS04935	COG3630	sodium ion export across plasma membrane
ASZ87_RS04940	COG0511	ligase activity, forming carbon-carbon bonds
ASZ87_RS04940	COG5016	pyruvate
ASZ87_RS04945	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ASZ87_RS04955	COG4565	transcriptional regulatory protein
ASZ87_RS04970	COG0583	DNA-binding transcription factor activity
ASZ87_RS04980	COG1115	amino acid carrier protein
ASZ87_RS04985	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ASZ87_RS04990	COG0583	DNA-binding transcription factor activity
ASZ87_RS05000	COG1120	ATPase activity
ASZ87_RS05005	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ87_RS05010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ87_RS05015	COG4592	Periplasmic binding protein
ASZ87_RS05025	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ87_RS05030	COG1169	isochorismate synthase
ASZ87_RS05035	COG1021	2,3-dihydroxybenzoate-AMP ligase
ASZ87_RS05040	COG3433	isochorismatase activity
ASZ87_RS05040	COG1535	isochorismatase
ASZ87_RS05045	COG1584	GPR1 FUN34 yaaH family protein
ASZ87_RS05055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASZ87_RS05055	COG0519	Catalyzes the synthesis of GMP from XMP
ASZ87_RS05060	COG0516	GMP reductase activity
ASZ87_RS05060	COG0517	IMP dehydrogenase activity
ASZ87_RS05065	COG1570	exodeoxyribonuclease VII activity
ASZ87_RS05080	COG1160	GTP binding
ASZ87_RS05085	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASZ87_RS05090	COG2976	Protein conserved in bacteria
ASZ87_RS05095	COG0124	histidyl-tRNA synthetase
ASZ87_RS05100	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASZ87_RS05110	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ASZ87_RS05115	COG0105	UTP biosynthetic process
ASZ87_RS05120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASZ87_RS05125	COG2975	iron-sulfur cluster assembly
ASZ87_RS05130	COG0633	Ferredoxin
ASZ87_RS05135	COG0443	Heat shock 70 kDa protein
ASZ87_RS05140	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASZ87_RS05150	COG0822	iron-sulfur transferase activity
ASZ87_RS05155	COG1104	cysteine desulfurase activity
ASZ87_RS05160	COG1959	2 iron, 2 sulfur cluster binding
ASZ87_RS05170	COG0483	inositol monophosphate 1-phosphatase activity
ASZ87_RS05175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASZ87_RS05180	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASZ87_RS05185	COG1862	Preprotein translocase
ASZ87_RS05205	COG0517	IMP dehydrogenase activity
ASZ87_RS05215	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ASZ87_RS05220	COG0583	DNA-binding transcription factor activity
ASZ87_RS05225	COG0450	alkyl hydroperoxide reductase
ASZ87_RS05230	COG3142	Participates in the control of copper homeostasis
ASZ87_RS05245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASZ87_RS05250	COG0581	inorganic phosphate transmembrane transporter activity
ASZ87_RS05260	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ASZ87_RS05265	COG0248	Ppx GppA phosphatase
ASZ87_RS05275	COG5002	protein histidine kinase activity
ASZ87_RS05280	COG0745	RESPONSE REGULATOR receiver
ASZ87_RS05290	COG0826	peptidase U32
ASZ87_RS05295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASZ87_RS05340	COG0542	response to heat
ASZ87_RS05350	COG0564	pseudouridine synthase activity
ASZ87_RS05355	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASZ87_RS05360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASZ87_RS05365	COG0077	Prephenate dehydratase
ASZ87_RS05365	COG1605	Chorismate mutase
ASZ87_RS05370	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASZ87_RS05375	COG5001	Diguanylate cyclase
ASZ87_RS05385	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ASZ87_RS05395	COG0488	(ABC) transporter
ASZ87_RS05405	COG1605	Chorismate mutase
ASZ87_RS05405	COG0287	Prephenate dehydrogenase
ASZ87_RS05410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASZ87_RS05420	COG3279	Response regulator of the LytR AlgR family
ASZ87_RS05430	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ASZ87_RS05435	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ASZ87_RS05450	COG1966	Carbon starvation protein
ASZ87_RS05455	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ASZ87_RS05460	COG1047	Peptidyl-prolyl cis-trans
ASZ87_RS05475	COG0196	riboflavin kinase activity
ASZ87_RS05480	COG0728	peptidoglycan biosynthetic process
ASZ87_RS05485	COG0268	Binds directly to 16S ribosomal RNA
ASZ87_RS05490	COG0640	Transcriptional regulator
ASZ87_RS05495	COG0583	DNA-binding transcription factor activity
ASZ87_RS05510	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASZ87_RS05515	COG0730	response to heat
ASZ87_RS05520	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ASZ87_RS05525	COG0494	nUDIX hydrolase
ASZ87_RS05535	COG0667	Aldo Keto reductase
ASZ87_RS05545	COG2204	response regulator
ASZ87_RS05550	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASZ87_RS05555	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ASZ87_RS05570	COG0513	Belongs to the DEAD box helicase family
ASZ87_RS05595	COG3153	acetyltransferase
ASZ87_RS05600	COG3154	lipid carrier protein
ASZ87_RS05610	COG0826	peptidase U32
ASZ87_RS05615	COG0826	peptidase U32
ASZ87_RS05640	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ASZ87_RS05650	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASZ87_RS05655	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASZ87_RS05660	COG0195	Participates in both transcription termination and antitermination
ASZ87_RS05665	COG0779	Required for maturation of 30S ribosomal subunits
ASZ87_RS05680	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASZ87_RS05695	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASZ87_RS05700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASZ87_RS05705	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ASZ87_RS05710	COG1534	Rna-binding protein
ASZ87_RS05715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASZ87_RS05720	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASZ87_RS05725	COG2027	D-alanyl-D-alanine carboxypeptidase
ASZ87_RS05730	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASZ87_RS05735	COG0739	heme binding
ASZ87_RS05750	COG0316	Belongs to the HesB IscA family
ASZ87_RS05755	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ASZ87_RS05765	COG0628	permease
ASZ87_RS05770	COG2813	Specifically methylates the guanine in position
ASZ87_RS05775	COG0784	Response regulator, receiver
ASZ87_RS05775	COG2205	protein histidine kinase activity
ASZ87_RS05785	COG0747	negative chemotaxis
ASZ87_RS05790	COG0601	transmembrane transport
ASZ87_RS05795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ87_RS05800	COG0444	Belongs to the ABC transporter superfamily
ASZ87_RS05805	COG4608	Belongs to the ABC transporter superfamily
ASZ87_RS05815	COG2971	BadF BadG BcrA BcrD
ASZ87_RS05835	COG3842	ATPase activity
ASZ87_RS05845	COG1840	ABC-type Fe3 transport system, periplasmic component
ASZ87_RS05850	COG0004	ammonium transporteR
ASZ87_RS05855	COG0347	Belongs to the P(II) protein family
ASZ87_RS05860	COG3112	Uncharacterised protein family (UPF0231)
ASZ87_RS05865	COG1049	propionate catabolic process, 2-methylcitrate cycle
ASZ87_RS05870	COG1752	Esterase of the alpha-beta hydrolase superfamily
ASZ87_RS05875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASZ87_RS05880	COG1643	Atp-dependent helicase
ASZ87_RS05890	COG1489	DNA binding
ASZ87_RS05900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASZ87_RS05910	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASZ87_RS05915	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASZ87_RS05920	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ASZ87_RS05925	COG0842	Transport permease protein
ASZ87_RS05930	COG1131	(ABC) transporter
ASZ87_RS05935	COG0659	secondary active sulfate transmembrane transporter activity
ASZ87_RS05940	COG0288	reversible hydration of carbon dioxide
ASZ87_RS05960	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ASZ87_RS05965	COG3107	peptidoglycan biosynthetic process
ASZ87_RS05970	COG0792	nuclease activity
ASZ87_RS05975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ASZ87_RS05980	COG2823	Periplasmic or secreted lipoprotein
ASZ87_RS05985	COG2969	positive regulation of protein catabolic process
ASZ87_RS05990	COG0625	glutathione transferase activity
ASZ87_RS05995	COG2857	Cytochrome c1
ASZ87_RS06000	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ASZ87_RS06005	COG0723	plastoquinol--plastocyanin reductase activity
ASZ87_RS06010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ASZ87_RS06015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASZ87_RS06025	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ASZ87_RS06035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASZ87_RS06040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASZ87_RS06045	COG0335	large ribosomal subunit rRNA binding
ASZ87_RS06050	COG0336	Belongs to the RNA methyltransferase TrmD family
ASZ87_RS06055	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASZ87_RS06060	COG0228	four-way junction DNA binding
ASZ87_RS06065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASZ87_RS06070	COG4137	Cytochrome C assembly protein
ASZ87_RS06075	COG4536	flavin adenine dinucleotide binding
ASZ87_RS06080	COG1854	S-ribosylhomocysteine lyase activity
ASZ87_RS06085	COG2918	glutathione biosynthetic process
ASZ87_RS06090	COG0612	Peptidase, M16
ASZ87_RS06095	COG1238	metal cluster binding
ASZ87_RS06105	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ASZ87_RS06110	COG5016	pyruvate
ASZ87_RS06110	COG0511	ligase activity, forming carbon-carbon bonds
ASZ87_RS06115	COG3630	sodium ion export across plasma membrane
ASZ87_RS06160	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ASZ87_RS06165	COG0527	aspartate kinase activity
ASZ87_RS06170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASZ87_RS06180	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ASZ87_RS06190	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASZ87_RS06195	COG4208	sulfate ABC transporter
ASZ87_RS06215	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASZ87_RS06220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASZ87_RS06230	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ASZ87_RS06235	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ASZ87_RS06240	COG0585	pseudouridine synthase activity
ASZ87_RS06245	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ASZ87_RS06250	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASZ87_RS06255	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ASZ87_RS06260	COG1968	undecaprenyl-diphosphatase activity
ASZ87_RS06265	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASZ87_RS06270	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ASZ87_RS06280	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASZ87_RS06290	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASZ87_RS06295	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ASZ87_RS06300	COG1610	YqeY-like protein
ASZ87_RS06305	COG0358	DNA primase activity
ASZ87_RS06320	COG0582	viral genome integration into host DNA
ASZ87_RS06325	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ASZ87_RS06335	COG2207	Transcriptional regulator
ASZ87_RS06340	COG0840	transmembrane signaling receptor activity
ASZ87_RS06355	COG2003	Belongs to the UPF0758 family
ASZ87_RS06390	COG0739	heme binding
ASZ87_RS06400	COG4969	Belongs to the N-Me-Phe pilin family
ASZ87_RS06425	COG0328	RNA-DNA hybrid ribonuclease activity
ASZ87_RS06475	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASZ87_RS06480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASZ87_RS06485	COG1349	DNA-binding transcription factor activity
ASZ87_RS06505	COG1279	arginine transmembrane transporter activity
ASZ87_RS06510	COG0668	transmembrane transport
ASZ87_RS06520	COG0191	fructose-bisphosphate aldolase activity
ASZ87_RS06525	COG0126	phosphoglycerate kinase activity
ASZ87_RS06530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASZ87_RS06535	COG4771	TonB-dependent receptor
ASZ87_RS06540	COG0583	DNA-binding transcription factor activity
ASZ87_RS06545	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASZ87_RS06555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASZ87_RS06565	COG2356	endonuclease I
ASZ87_RS06570	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASZ87_RS06575	COG0189	ligase activity
ASZ87_RS06580	COG1678	Uncharacterized ACR, COG1678
ASZ87_RS06585	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASZ87_RS06590	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASZ87_RS06610	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ASZ87_RS06615	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ASZ87_RS06620	COG0762	integral membrane protein
ASZ87_RS06625	COG1872	DUF167
ASZ87_RS06635	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASZ87_RS06640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASZ87_RS06645	COG2066	Belongs to the glutaminase family
ASZ87_RS06655	COG1194	a g-specific adenine glycosylase
ASZ87_RS06660	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ASZ87_RS06665	COG0741	lytic transglycosylase activity
ASZ87_RS06690	COG0840	transmembrane signaling receptor activity
ASZ87_RS06720	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASZ87_RS06725	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASZ87_RS06730	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASZ87_RS06735	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ASZ87_RS06740	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ASZ87_RS06745	COG2967	ApaG domain
ASZ87_RS06750	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASZ87_RS06760	COG3610	response to peptide
ASZ87_RS06765	COG2966	Psort location CytoplasmicMembrane, score
ASZ87_RS06770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ASZ87_RS06775	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASZ87_RS06780	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASZ87_RS06785	COG0142	geranyltranstransferase activity
ASZ87_RS06790	COG0531	amino acid
ASZ87_RS06795	COG0039	L-malate dehydrogenase activity
ASZ87_RS06800	COG1438	arginine binding
ASZ87_RS06810	COG2358	TRAP transporter, solute receptor (TAXI family
ASZ87_RS06820	COG0589	response to stress
ASZ87_RS06840	COG2235	arginine
ASZ87_RS06845	COG0312	modulator of DNA gyrase
ASZ87_RS06850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASZ87_RS06855	COG3164	Protein of unknown function
ASZ87_RS06865	COG0424	maF-like protein
ASZ87_RS06870	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ASZ87_RS06875	COG1792	Involved in formation and maintenance of cell shape
ASZ87_RS06880	COG1077	Cell shape determining protein MreB Mrl
ASZ87_RS06910	COG2165	general secretion pathway protein
ASZ87_RS06915	COG2165	general secretion pathway protein
ASZ87_RS06925	COG1459	type II secretion system
ASZ87_RS06930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ87_RS06940	COG3409	Peptidoglycan-binding domain 1 protein
ASZ87_RS06940	COG3267	Type II secretory pathway component ExeA
ASZ87_RS06965	COG2200	EAL domain
ASZ87_RS06965	COG2199	diguanylate cyclase activity
ASZ87_RS06970	COG0629	single-stranded DNA binding
ASZ87_RS06985	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASZ87_RS06995	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ASZ87_RS07000	COG0527	aspartate kinase activity
ASZ87_RS07005	COG0646	methionine synthase
ASZ87_RS07005	COG1410	methionine synthase
ASZ87_RS07045	COG0175	sulfate reduction
ASZ87_RS07055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASZ87_RS07080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASZ87_RS07085	COG0735	belongs to the Fur family
ASZ87_RS07105	COG0432	Pfam Uncharacterised protein family UPF0047
ASZ87_RS07110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASZ87_RS07125	COG0359	binds to the 23S rRNA
ASZ87_RS07130	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASZ87_RS07135	COG2965	DNA replication, synthesis of RNA primer
ASZ87_RS07140	COG0360	Binds together with S18 to 16S ribosomal RNA
ASZ87_RS07150	COG2906	2 iron, 2 sulfur cluster binding
ASZ87_RS07155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASZ87_RS07160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASZ87_RS07165	COG0049	tRNA binding
ASZ87_RS07180	COG2923	Belongs to the DsrF TusC family
ASZ87_RS07185	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ASZ87_RS07190	COG2964	Protein conserved in bacteria
ASZ87_RS07195	COG0545	Peptidyl-prolyl cis-trans isomerase
ASZ87_RS07205	COG2900	Belongs to the SlyX family
ASZ87_RS07210	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ASZ87_RS07215	COG0330	HflC and HflK could
ASZ87_RS07220	COG0330	HflC and HflK could
ASZ87_RS07225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASZ87_RS07230	COG1923	regulation of RNA biosynthetic process
ASZ87_RS07235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASZ87_RS07240	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ASZ87_RS07250	COG0802	atpase or kinase
ASZ87_RS07255	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ASZ87_RS07300	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ASZ87_RS07305	COG1162	GTPase activity
ASZ87_RS07310	COG0688	phosphatidylethanolamine metabolic process
ASZ87_RS07315	COG0471	metal ion transport
ASZ87_RS07325	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ASZ87_RS07330	COG4942	peptidase
ASZ87_RS07345	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ASZ87_RS07350	COG2816	NAD+ diphosphatase activity
ASZ87_RS07355	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ASZ87_RS07360	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASZ87_RS07365	COG0085	RNA polymerase activity
ASZ87_RS07370	COG0222	ribosome binding
ASZ87_RS07375	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASZ87_RS07385	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASZ87_RS07390	COG0250	Participates in transcription elongation, termination and antitermination
ASZ87_RS07395	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASZ87_RS07400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASZ87_RS07425	COG1072	(Pantothenic acid kinase))
ASZ87_RS07435	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ASZ87_RS07450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASZ87_RS07500	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASZ87_RS07515	COG3118	belongs to the thioredoxin family
ASZ87_RS07520	COG0513	Belongs to the DEAD box helicase family
ASZ87_RS07525	COG0248	Ppx GppA phosphatase
ASZ87_RS07530	COG0784	Response regulator, receiver
ASZ87_RS07530	COG2205	protein histidine kinase activity
ASZ87_RS07535	COG2814	Major facilitator Superfamily
ASZ87_RS07575	COG0488	(ABC) transporter
ASZ87_RS07620	COG3941	tape measure
ASZ87_RS07650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASZ87_RS07655	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ASZ87_RS07660	COG0511	ligase activity, forming carbon-carbon bonds
ASZ87_RS07665	COG0439	Biotin carboxylase
ASZ87_RS07670	COG2264	protein methyltransferase activity
ASZ87_RS07675	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASZ87_RS07680	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ASZ87_RS07685	COG1609	Transcriptional regulator
ASZ87_RS07690	COG0129	dihydroxy-acid dehydratase activity
ASZ87_RS07695	COG3265	gluconokinase activity
ASZ87_RS07705	COG0800	Aldolase
ASZ87_RS07725	COG0840	transmembrane signaling receptor activity
ASZ87_RS07730	COG1982	Orn Lys Arg decarboxylase major
ASZ87_RS07735	COG0531	amino acid
ASZ87_RS07740	COG3710	Transcriptional regulator
ASZ87_RS07745	COG0789	Transcriptional regulator
ASZ87_RS07760	COG0151	Belongs to the GarS family
ASZ87_RS07770	COG0776	regulation of translation
ASZ87_RS07780	COG1253	flavin adenine dinucleotide binding
ASZ87_RS07785	COG1940	carbohydrate kinase activity
ASZ87_RS07795	COG3068	Protein conserved in bacteria
ASZ87_RS07805	COG1573	uracil-dna glycosylase
ASZ87_RS07810	COG0668	transmembrane transport
ASZ87_RS07815	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ASZ87_RS07820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASZ87_RS07865	COG1012	belongs to the aldehyde dehydrogenase family
ASZ87_RS07865	COG1454	alcohol dehydrogenase
ASZ87_RS07870	COG0318	PFAM AMP-dependent synthetase and ligase
ASZ87_RS07900	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ASZ87_RS07905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASZ87_RS07910	COG0662	Cupin 2, conserved barrel domain protein
ASZ87_RS07910	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ASZ87_RS07915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASZ87_RS07950	COG1519	Transferase
ASZ87_RS07980	COG3642	lipopolysaccharide core region biosynthetic process
ASZ87_RS07985	COG0859	PFAM glycosyl transferase family 9
ASZ87_RS07990	COG0463	Glycosyl transferase, family 2
ASZ87_RS07995	COG0859	PFAM glycosyl transferase family 9
ASZ87_RS08000	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ASZ87_RS08005	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASZ87_RS08015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASZ87_RS08020	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASZ87_RS08025	COG2003	Belongs to the UPF0758 family
ASZ87_RS08035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASZ87_RS08045	COG1309	transcriptional regulator
ASZ87_RS08050	COG1560	Kdo2-lipid A biosynthetic process
ASZ87_RS08055	COG1560	Kdo2-lipid A biosynthetic process
ASZ87_RS08060	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASZ87_RS08065	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ASZ87_RS08070	COG1561	YicC-like family, N-terminal region
ASZ87_RS08075	COG2862	Uncharacterized protein family, UPF0114
ASZ87_RS08080	COG1263	PTS System
ASZ87_RS08080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ87_RS08085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ASZ87_RS08110	COG1120	ATPase activity
ASZ87_RS08115	COG4774	siderophore transport
ASZ87_RS08120	COG1132	(ABC) transporter
ASZ87_RS08135	COG0514	ATP-dependent DNA helicase (RecQ)
ASZ87_RS08140	COG2962	Rard protein
ASZ87_RS08155	COG1280	lysine exporter protein (LysE YggA)
ASZ87_RS08160	COG0210	DNA helicase
ASZ87_RS08170	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ASZ87_RS08175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ87_RS08215	COG3621	Patatin-like phospholipase
ASZ87_RS08240	COG2131	deaminase
ASZ87_RS08250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASZ87_RS08255	COG0601	transmembrane transport
ASZ87_RS08260	COG0747	negative chemotaxis
ASZ87_RS08310	COG1309	transcriptional regulator
ASZ87_RS08315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASZ87_RS08320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASZ87_RS08325	COG2960	long-chain fatty acid transporting porin activity
ASZ87_RS08330	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ASZ87_RS08335	COG0583	DNA-binding transcription factor activity
ASZ87_RS08410	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ASZ87_RS08415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASZ87_RS08420	COG1739	Uncharacterized protein family UPF0029
ASZ87_RS08430	COG0183	Belongs to the thiolase family
ASZ87_RS08435	COG0583	DNA-binding transcription factor activity
ASZ87_RS08440	COG2814	Major facilitator Superfamily
ASZ87_RS08445	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASZ87_RS08450	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASZ87_RS08455	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASZ87_RS08460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASZ87_RS08465	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASZ87_RS08470	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASZ87_RS08475	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ASZ87_RS08485	COG0356	it plays a direct role in the translocation of protons across the membrane
ASZ87_RS08490	COG3312	ion transport
ASZ87_RS08495	COG1475	DNA binding
ASZ87_RS08500	COG1192	Involved in chromosome partitioning
ASZ87_RS08510	COG0445	tRNA wobble uridine modification
ASZ87_RS08520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASZ87_RS08525	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASZ87_RS08530	COG0706	membrane insertase activity
ASZ87_RS08540	COG0594	ribonuclease P activity
ASZ87_RS08545	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASZ87_RS08550	COG1126	abc transporter atp-binding protein
ASZ87_RS08565	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASZ87_RS08570	COG0592	DNA-directed DNA polymerase activity
ASZ87_RS08575	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ASZ87_RS08580	COG0187	DNA topoisomerase II activity
ASZ87_RS08595	COG0071	Belongs to the small heat shock protein (HSP20) family
ASZ87_RS08600	COG3977	Valine--pyruvate aminotransferase
ASZ87_RS08610	COG0751	glycine-tRNA ligase activity
ASZ87_RS08615	COG0752	glycyl-tRNA synthetase alpha subunit
ASZ87_RS08620	COG2119	membrane
ASZ87_RS08630	COG0425	Belongs to the sulfur carrier protein TusA family
ASZ87_RS08640	COG0604	alcohol dehydrogenase
ASZ87_RS08650	COG0129	dihydroxy-acid dehydratase activity
ASZ87_RS08655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASZ87_RS08670	COG0606	chelatase, subunit chli
ASZ87_RS08675	COG0204	Acyl-transferase
ASZ87_RS08680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASZ87_RS08685	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ASZ87_RS08700	COG3084	Protein conserved in bacteria
ASZ87_RS08710	COG4326	sporulation control protein
ASZ87_RS08715	COG1272	protein, Hemolysin III
ASZ87_RS08725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASZ87_RS08730	COG0569	domain protein
ASZ87_RS08735	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ASZ87_RS08735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASZ87_RS08740	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASZ87_RS08745	COG0242	peptide deformylase activity
ASZ87_RS08750	COG1652	LysM domain
ASZ87_RS08755	COG0758	DNA mediated transformation
ASZ87_RS08760	COG2922	Belongs to the Smg family
ASZ87_RS08765	COG0551	DNA topoisomerase type I activity
ASZ87_RS08770	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ASZ87_RS08775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASZ87_RS08780	COG0009	L-threonylcarbamoyladenylate synthase
ASZ87_RS08785	COG0408	coproporphyrinogen oxidase activity
ASZ87_RS08790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASZ87_RS08800	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ASZ87_RS08840	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASZ87_RS08845	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ASZ87_RS08855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ASZ87_RS08860	COG2104	thiamine diphosphate biosynthetic process
ASZ87_RS08865	COG2022	thiamine diphosphate biosynthetic process
ASZ87_RS08870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASZ87_RS08875	COG0006	proline dipeptidase activity
ASZ87_RS08875	COG0006	proline dipeptidase activity
ASZ87_RS08895	COG1522	sequence-specific DNA binding
ASZ87_RS08900	COG5002	protein histidine kinase activity
ASZ87_RS08900	COG5001	Diguanylate cyclase
ASZ87_RS08920	COG0589	response to stress
ASZ87_RS08930	COG1528	Iron-storage protein
ASZ87_RS08940	COG2081	HI0933 family
ASZ87_RS08950	COG1322	Protein conserved in bacteria
ASZ87_RS08955	COG2226	methyltransferase
ASZ87_RS08970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASZ87_RS08975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASZ87_RS08980	COG0805	protein transport
ASZ87_RS08985	COG1858	cytochrome C peroxidase
ASZ87_RS08990	COG0534	Mate efflux family protein
ASZ87_RS09000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASZ87_RS09015	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ASZ87_RS09020	COG3161	chorismate lyase activity
ASZ87_RS09030	COG1580	Controls the rotational direction of flagella during chemotaxis
ASZ87_RS09035	COG0840	transmembrane signaling receptor activity
ASZ87_RS09045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASZ87_RS09055	COG0084	hydrolase, TatD family'
ASZ87_RS09070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASZ87_RS09070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASZ87_RS09090	COG3078	GTPase activator activity
ASZ87_RS09105	COG3071	HemY protein
ASZ87_RS09110	COG2959	enzyme of heme biosynthesis
ASZ87_RS09115	COG1587	Uroporphyrinogen-III synthase
ASZ87_RS09120	COG0181	hydroxymethylbilane synthase activity
ASZ87_RS09135	COG1965	Belongs to the frataxin family
ASZ87_RS09145	COG0019	diaminopimelate decarboxylase activity
ASZ87_RS09150	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ASZ87_RS09160	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ASZ87_RS09165	COG1011	Hydrolase
ASZ87_RS09170	COG3287	FIST C domain
ASZ87_RS09170	COG2199	diguanylate cyclase activity
ASZ87_RS09170	COG2200	EAL domain
ASZ87_RS09190	COG0561	phosphatase activity
ASZ87_RS09195	COG2267	carboxylic ester hydrolase activity
ASZ87_RS09200	COG1280	lysine exporter protein (LysE YggA)
ASZ87_RS09205	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ASZ87_RS09210	COG0783	Belongs to the Dps family
ASZ87_RS09250	COG0742	ribosomal rna small subunit methyltransferase
ASZ87_RS09255	COG0552	protein localization to endoplasmic reticulum
ASZ87_RS09260	COG2884	Cell division ATP-binding protein ftsE
ASZ87_RS09265	COG2177	Part of the ABC transporter FtsEX involved in
ASZ87_RS09270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASZ87_RS09275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ87_RS09295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASZ87_RS09300	COG4206	TonB-dependent receptor
ASZ87_RS09305	COG1404	Belongs to the peptidase S8 family
ASZ87_RS09310	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ASZ87_RS09385	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ASZ87_RS09390	COG5001	Diguanylate cyclase
ASZ87_RS09390	COG3300	MHYT domain
ASZ87_RS09400	COG3852	Histidine kinase
ASZ87_RS09410	COG0174	glutamine synthetase
ASZ87_RS09420	COG1217	gtp-binding protein TYPA
ASZ87_RS09430	COG1295	ribonuclease BN
ASZ87_RS09435	COG1490	D-aminoacyl-tRNA deacylase activity
ASZ87_RS09440	COG0456	acetyltransferase
ASZ87_RS09450	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ASZ87_RS09455	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ASZ87_RS09460	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ASZ87_RS09465	COG3031	protein transport across the cell outer membrane
ASZ87_RS09475	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ87_RS09480	COG1459	type II secretion system
ASZ87_RS09485	COG2165	general secretion pathway protein
ASZ87_RS09490	COG2165	general secretion pathway protein
ASZ87_RS09495	COG2165	general secretion pathway protein
ASZ87_RS09500	COG4795	General secretion pathway protein
ASZ87_RS09505	COG3156	type II secretion system protein K
ASZ87_RS09510	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ASZ87_RS09515	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ASZ87_RS09525	COG1218	3'(2'),5'-bisphosphate nucleotidase
ASZ87_RS09530	COG0494	nUDIX hydrolase
ASZ87_RS09540	COG1040	competence protein
ASZ87_RS09555	COG0596	Alpha beta hydrolase
ASZ87_RS09565	COG2183	response to ionizing radiation
ASZ87_RS09570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASZ87_RS09585	COG2233	PERMEase
ASZ87_RS09590	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASZ87_RS09595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASZ87_RS09600	COG1758	RNA polymerase activity
ASZ87_RS09605	COG0194	GDP metabolic process
ASZ87_RS09610	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ASZ87_RS09615	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASZ87_RS09635	COG4232	protein-disulfide reductase activity
ASZ87_RS09650	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ASZ87_RS09655	COG1027	Aspartate ammonia-lyase
ASZ87_RS09660	COG3706	GGDEF domain
ASZ87_RS09665	COG3030	protein affecting phage T7 exclusion by the F plasmid
ASZ87_RS09670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ASZ87_RS09680	COG2205	protein histidine kinase activity
ASZ87_RS09685	COG0745	RESPONSE REGULATOR receiver
ASZ87_RS09695	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ASZ87_RS09700	COG0205	6-phosphofructokinase activity
ASZ87_RS09705	COG1494	fructose-1,6-bisphosphatase
ASZ87_RS09710	COG3074	FtsZ-dependent cytokinesis
ASZ87_RS09715	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ASZ87_RS09720	COG0527	aspartate kinase activity
ASZ87_RS09720	COG0460	homoserine dehydrogenase
ASZ87_RS09725	COG0626	cystathionine gamma-synthase activity
ASZ87_RS09730	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
ASZ87_RS09735	COG0281	malic enzyme
ASZ87_RS09740	COG0254	rRNA binding
ASZ87_RS09745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASZ87_RS09750	COG1609	Transcriptional regulator
ASZ87_RS09755	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASZ87_RS09760	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ASZ87_RS09765	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ASZ87_RS09770	COG1575	Belongs to the MenA family. Type 1 subfamily
ASZ87_RS09775	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ASZ87_RS09780	COG0534	Mate efflux family protein
ASZ87_RS09785	COG0149	triose-phosphate isomerase activity
ASZ87_RS09810	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASZ87_RS09815	COG0459	protein refolding
ASZ87_RS09825	COG1509	lysine 2,3-aminomutase activity
ASZ87_RS09830	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASZ87_RS09840	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ASZ87_RS09845	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASZ87_RS09850	COG1053	succinate dehydrogenase
ASZ87_RS09855	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ASZ87_RS09860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASZ87_RS09865	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ASZ87_RS09870	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASZ87_RS09875	COG1045	serine acetyltransferase
ASZ87_RS09885	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ASZ87_RS09890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASZ87_RS09895	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASZ87_RS09900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASZ87_RS09905	COG0137	argininosuccinate synthase activity
ASZ87_RS09915	COG0165	Argininosuccinate lyase
ASZ87_RS09925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ87_RS09930	COG0678	peroxiredoxin activity
ASZ87_RS09930	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASZ87_RS09940	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ASZ87_RS09970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ASZ87_RS09975	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASZ87_RS09985	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ASZ87_RS09990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASZ87_RS09995	COG0546	phosphoglycolate phosphatase activity
ASZ87_RS10000	COG0180	Tryptophanyl-tRNA synthetase
ASZ87_RS10015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASZ87_RS10025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASZ87_RS10035	COG1012	belongs to the aldehyde dehydrogenase family
ASZ87_RS10050	COG3954	Phosphoribulokinase
ASZ87_RS10060	COG0429	hydrolase of the alpha beta-hydrolase fold
ASZ87_RS10070	COG0488	(ABC) transporter
ASZ87_RS10075	COG2249	NAD(P)H dehydrogenase (quinone) activity
ASZ87_RS10090	COG1047	Peptidyl-prolyl cis-trans
ASZ87_RS10110	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ASZ87_RS10115	COG3083	sulfuric ester hydrolase activity
ASZ87_RS10120	COG0557	exoribonuclease II activity
ASZ87_RS10125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASZ87_RS10130	COG0051	transcription antitermination factor activity, RNA binding
ASZ87_RS10135	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASZ87_RS10140	COG0088	Forms part of the polypeptide exit tunnel
ASZ87_RS10145	COG0089	rRNA binding
ASZ87_RS10150	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASZ87_RS10155	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASZ87_RS10160	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASZ87_RS10165	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASZ87_RS10170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASZ87_RS10175	COG0255	Belongs to the universal ribosomal protein uL29 family
ASZ87_RS10180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASZ87_RS10185	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASZ87_RS10190	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASZ87_RS10195	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASZ87_RS10200	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASZ87_RS10205	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASZ87_RS10215	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASZ87_RS10220	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASZ87_RS10225	COG1841	ribosomal large subunit assembly
ASZ87_RS10235	COG0201	protein transport
ASZ87_RS10240	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASZ87_RS10245	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASZ87_RS10250	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASZ87_RS10255	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASZ87_RS10260	COG0202	RNA polymerase activity
ASZ87_RS10265	COG0203	ribosomal protein L17
ASZ87_RS10275	COG0545	Peptidyl-prolyl cis-trans isomerase
ASZ87_RS10280	COG3061	Opacity-associated protein A
ASZ87_RS10280	COG3266	domain, Protein
ASZ87_RS10285	COG0697	spore germination
ASZ87_RS10290	COG2153	protein acetylation
ASZ87_RS10295	COG0513	Belongs to the DEAD box helicase family
ASZ87_RS10305	COG0737	Belongs to the 5'-nucleotidase family
ASZ87_RS10310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASZ87_RS10310	COG1648	precorrin-2 dehydrogenase activity
ASZ87_RS10325	COG0529	Catalyzes the synthesis of activated sulfate
ASZ87_RS10345	COG1136	(ABC) transporter
ASZ87_RS10360	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ASZ87_RS10365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ87_RS10370	COG0729	surface antigen
ASZ87_RS10380	COG2105	PFAM AIG2 family protein
ASZ87_RS10385	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ASZ87_RS10400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASZ87_RS10405	COG0163	prenyltransferase activity
ASZ87_RS10415	COG1178	ABC-type Fe3 transport system permease component
ASZ87_RS10420	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ASZ87_RS10425	COG3028	Belongs to the UPF0307 family
ASZ87_RS10430	COG0312	modulator of DNA gyrase
ASZ87_RS10435	COG2239	Acts as a magnesium transporter
ASZ87_RS10440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ87_RS10445	COG1660	Displays ATPase and GTPase activities
ASZ87_RS10450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ87_RS10455	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASZ87_RS10465	COG1137	ATPase activity
ASZ87_RS10470	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ASZ87_RS10485	COG0517	IMP dehydrogenase activity
ASZ87_RS10485	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ASZ87_RS10500	COG1127	ABC transporter
ASZ87_RS10505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASZ87_RS10510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASZ87_RS10515	COG2854	intermembrane phospholipid transfer
ASZ87_RS10525	COG5007	Belongs to the BolA IbaG family
ASZ87_RS10530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASZ87_RS10540	COG0251	oxidation-reduction process
ASZ87_RS10550	COG0540	Belongs to the ATCase OTCase family
ASZ87_RS10560	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ASZ87_RS10575	COG0564	pseudouridine synthase activity
ASZ87_RS10580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASZ87_RS10585	COG0525	valine-tRNA ligase activity
ASZ87_RS10590	COG2927	DNA polymerase III (CHI subunit)
ASZ87_RS10595	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASZ87_RS10600	COG0795	lipopolysaccharide-transporting ATPase activity
ASZ87_RS10605	COG0795	lipopolysaccharide-transporting ATPase activity
ASZ87_RS10620	COG3437	response regulator, receiver
ASZ87_RS10665	COG0066	3-isopropylmalate dehydratase activity
ASZ87_RS10670	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ASZ87_RS10675	COG0473	3-isopropylmalate dehydrogenase activity
ASZ87_RS10700	COG0583	DNA-binding transcription factor activity
ASZ87_RS10705	COG1022	Amp-dependent synthetase and ligase
ASZ87_RS10710	COG0028	Belongs to the TPP enzyme family
ASZ87_RS10715	COG0440	acetolactate synthase activity
ASZ87_RS10720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASZ87_RS10725	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ASZ87_RS10730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASZ87_RS10740	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ASZ87_RS10745	COG3079	Belongs to the UPF0149 family
ASZ87_RS10750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ87_RS10755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ87_RS10770	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ASZ87_RS10780	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ASZ87_RS10790	COG1595	DNA-templated transcription, initiation
ASZ87_RS10805	COG3086	response to oxidative stress
ASZ87_RS10810	COG0481	GTPase activity
ASZ87_RS10825	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASZ87_RS10830	COG1381	Involved in DNA repair and RecF pathway recombination
ASZ87_RS10835	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ASZ87_RS10855	COG5001	Diguanylate cyclase
ASZ87_RS10870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASZ87_RS10875	COG3956	TIGRFAM MazG family protein
ASZ87_RS10880	COG0504	CTP synthase activity
ASZ87_RS10885	COG0148	phosphopyruvate hydratase activity
ASZ87_RS10895	COG3267	Type II secretory pathway component ExeA
ASZ87_RS10895	COG3409	Peptidoglycan-binding domain 1 protein
ASZ87_RS10910	COG0306	phosphate transporter
ASZ87_RS10915	COG1392	Phosphate transport regulator
ASZ87_RS10920	COG3025	triphosphatase activity
ASZ87_RS10925	COG0840	transmembrane signaling receptor activity
ASZ87_RS10930	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ASZ87_RS10940	COG1538	Outer membrane efflux protein
ASZ87_RS10945	COG0494	nUDIX hydrolase
ASZ87_RS10950	COG3151	Protein conserved in bacteria
ASZ87_RS10960	COG3150	esterase
ASZ87_RS10965	COG0187	DNA topoisomerase II activity
ASZ87_RS10970	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASZ87_RS10980	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ASZ87_RS10985	COG0237	dephospho-CoA kinase activity
ASZ87_RS10995	COG1459	type II secretion system
ASZ87_RS11000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASZ87_RS11020	COG0716	FMN binding
ASZ87_RS11025	COG4974	Belongs to the 'phage' integrase family
ASZ87_RS11030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASZ87_RS11035	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASZ87_RS11040	COG0737	Belongs to the 5'-nucleotidase family
ASZ87_RS11050	COG2186	Transcriptional regulator
ASZ87_RS11055	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ASZ87_RS11060	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASZ87_RS11065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASZ87_RS11080	COG3116	cell division
ASZ87_RS11085	COG0768	penicillin binding
ASZ87_RS11090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASZ87_RS11095	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASZ87_RS11105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASZ87_RS11110	COG0772	Belongs to the SEDS family
ASZ87_RS11120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASZ87_RS11125	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ASZ87_RS11130	COG0849	cell division
ASZ87_RS11135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ASZ87_RS11140	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ASZ87_RS11150	COG0653	protein targeting
ASZ87_RS11160	COG0494	nUDIX hydrolase
ASZ87_RS11165	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ASZ87_RS11175	COG0505	Belongs to the CarA family
ASZ87_RS11180	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASZ87_RS11205	COG4172	Belongs to the ABC transporter superfamily
ASZ87_RS11215	COG0730	response to heat
ASZ87_RS11220	COG0583	DNA-binding transcription factor activity
ASZ87_RS11225	COG2860	membrane
ASZ87_RS11230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASZ87_RS11240	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ASZ87_RS11250	COG0493	'glutamate synthase
ASZ87_RS11255	COG0070	glutamate synthase
ASZ87_RS11255	COG0067	glutamate synthase
ASZ87_RS11255	COG0069	glutamate synthase activity
ASZ87_RS11265	COG0067	glutamate synthase
ASZ87_RS11265	COG0070	glutamate synthase
ASZ87_RS11265	COG0069	glutamate synthase activity
ASZ87_RS11270	COG1242	4 iron, 4 sulfur cluster binding
ASZ87_RS11275	COG5001	Diguanylate cyclase
ASZ87_RS11275	COG3706	GGDEF domain
ASZ87_RS11275	COG2203	Gaf domain
ASZ87_RS11275	COG4251	negative regulation of phosphorylation
ASZ87_RS11280	COG2198	Histidine kinase
ASZ87_RS11280	COG0784	Response regulator, receiver
ASZ87_RS11280	COG5002	protein histidine kinase activity
ASZ87_RS11285	COG0745	RESPONSE REGULATOR receiver
ASZ87_RS11295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ASZ87_RS11320	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ASZ87_RS11325	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
ASZ87_RS11330	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ASZ87_RS11335	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASZ87_RS11350	COG1115	amino acid carrier protein
ASZ87_RS11355	COG3022	response to hydroperoxide
ASZ87_RS11360	COG0084	hydrolase, TatD family'
ASZ87_RS11365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASZ87_RS11375	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ASZ87_RS11380	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ASZ87_RS11385	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ASZ87_RS11390	COG0813	purine-nucleoside phosphorylase activity
ASZ87_RS11400	COG0560	Phosphoserine phosphatase
ASZ87_RS11415	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASZ87_RS11420	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASZ87_RS11425	COG1022	Amp-dependent synthetase and ligase
ASZ87_RS11440	COG3250	beta-galactosidase activity
ASZ87_RS11445	COG1609	Transcriptional regulator
ASZ87_RS11450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASZ87_RS11465	COG0569	domain protein
ASZ87_RS11465	COG0189	ligase activity
ASZ87_RS11470	COG0456	acetyltransferase
ASZ87_RS11480	COG2171	N-acyltransferase activity
ASZ87_RS11485	COG3141	response to X-ray
ASZ87_RS11500	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ASZ87_RS11505	COG1074	ATP-dependent DNA helicase activity
ASZ87_RS11510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASZ87_RS11525	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ASZ87_RS11525	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASZ87_RS11535	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ASZ87_RS11540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ASZ87_RS11545	COG2166	iron-sulfur cluster assembly
ASZ87_RS11550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASZ87_RS11555	COG0693	protein deglycase activity
ASZ87_RS11560	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ASZ87_RS11565	COG3248	Nucleoside-binding outer membrane protein
ASZ87_RS11575	COG1595	DNA-templated transcription, initiation
ASZ87_RS11585	COG2211	Major facilitator Superfamily
ASZ87_RS11590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ASZ87_RS11600	COG2813	Specifically methylates the guanine in position
ASZ87_RS11605	COG0271	Belongs to the BolA IbaG family
ASZ87_RS11610	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ87_RS11615	COG1805	sodium ion transport
ASZ87_RS11620	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ87_RS11625	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ87_RS11630	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASZ87_RS11635	COG2871	sodium ion transport
ASZ87_RS11640	COG1477	protein flavinylation
ASZ87_RS11660	COG3706	GGDEF domain
ASZ87_RS11665	COG0733	neurotransmitter:sodium symporter activity
ASZ87_RS11675	COG0189	ligase activity
ASZ87_RS11680	COG0189	ligase activity
ASZ87_RS11680	COG4067	protein conserved in archaea
ASZ87_RS11685	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASZ87_RS11690	COG2252	PERMEase
ASZ87_RS11695	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ASZ87_RS11700	COG1073	alpha beta
ASZ87_RS11710	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ASZ87_RS11715	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ASZ87_RS11720	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASZ87_RS11725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASZ87_RS11725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASZ87_RS11740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASZ87_RS11745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASZ87_RS11750	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ASZ87_RS11755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASZ87_RS11770	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ASZ87_RS11775	COG0024	Methionine aminopeptidase
ASZ87_RS11780	COG0052	Belongs to the universal ribosomal protein uS2 family
ASZ87_RS11785	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASZ87_RS11790	COG0528	UMP kinase activity
ASZ87_RS11795	COG0233	cytoplasmic translational termination
ASZ87_RS11800	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASZ87_RS11805	COG0575	Belongs to the CDS family
ASZ87_RS11810	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASZ87_RS11815	COG0750	zinc metalloprotease
ASZ87_RS11825	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ASZ87_RS11830	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ87_RS11835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASZ87_RS11840	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ87_RS11845	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ87_RS11850	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASZ87_RS11855	COG0587	DNA-directed DNA polymerase activity
ASZ87_RS11860	COG0825	malonyl-CoA metabolic process
ASZ87_RS11865	COG0037	tRNA processing
ASZ87_RS11875	COG3479	Phenolic acid decarboxylase
ASZ87_RS11880	COG0347	Belongs to the P(II) protein family
ASZ87_RS11885	COG3021	interspecies interaction between organisms
ASZ87_RS11890	COG0741	lytic transglycosylase activity
ASZ87_RS11890	COG1388	LysM domain
ASZ87_RS11895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASZ87_RS11900	COG2226	methyltransferase
ASZ87_RS11905	COG0328	RNA-DNA hybrid ribonuclease activity
ASZ87_RS11920	COG1960	acyl-CoA dehydrogenase activity
ASZ87_RS11925	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ASZ87_RS11930	COG0121	glutamine amidotransferase
ASZ87_RS11935	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ASZ87_RS11940	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASZ87_RS11945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ASZ87_RS11955	COG1187	pseudouridine synthase activity
ASZ87_RS11960	COG2840	Smr protein MutS2
ASZ87_RS11975	COG3735	TraB family
ASZ87_RS11990	COG2217	Heavy metal translocating P-type atpase
ASZ87_RS11990	COG2608	mercury ion transmembrane transporter activity
ASZ87_RS11995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASZ87_RS12015	COG4774	siderophore transport
ASZ87_RS12015	COG1629	transport
ASZ87_RS12020	COG2375	cellular response to nickel ion
ASZ87_RS12025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASZ87_RS12025	COG2226	methyltransferase
ASZ87_RS12025	COG3433	isochorismatase activity
ASZ87_RS12060	COG0784	Response regulator, receiver
ASZ87_RS12060	COG0835	chemotaxis
ASZ87_RS12065	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASZ87_RS12070	COG1815	bacterial-type flagellum-dependent cell motility
ASZ87_RS12085	COG1749	Flagellar hook protein flgE
ASZ87_RS12090	COG4787	bacterial-type flagellum-dependent cell motility
ASZ87_RS12100	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ASZ87_RS12105	COG1706	bacterial-type flagellum-dependent cell motility
ASZ87_RS12110	COG1705	Flagellar rod assembly protein muramidase FlgJ
ASZ87_RS12110	COG3951	Flagellar rod assembly protein muramidase FlgJ
ASZ87_RS12125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ87_RS12130	COG4974	Belongs to the 'phage' integrase family
ASZ87_RS12230	COG4695	Portal protein
ASZ87_RS12355	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ87_RS12440	COG0012	GTP binding
ASZ87_RS12445	COG0193	aminoacyl-tRNA hydrolase activity
ASZ87_RS12450	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASZ87_RS12455	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ASZ87_RS12460	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ASZ87_RS12465	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ASZ87_RS12470	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASZ87_RS12475	COG2890	protein-(glutamine-N5) methyltransferase activity
ASZ87_RS12485	COG2912	Transglutaminase-like superfamily
ASZ87_RS12490	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ASZ87_RS12495	COG0737	Belongs to the 5'-nucleotidase family
ASZ87_RS12500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASZ87_RS12505	COG2233	PERMEase
ASZ87_RS12525	COG1393	Belongs to the ArsC family
ASZ87_RS12530	COG4783	chaperone-mediated protein folding
ASZ87_RS12550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASZ87_RS12565	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ASZ87_RS12575	COG1876	peptidase activity
ASZ87_RS12585	COG1393	Belongs to the ArsC family
ASZ87_RS12605	COG2837	iron assimilation
ASZ87_RS12610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ87_RS12615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ87_RS12620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASZ87_RS12625	COG1334	flagellar protein FlaG
ASZ87_RS12630	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ASZ87_RS12640	COG1516	flagellar protein fliS
ASZ87_RS12660	COG1677	Flagellar hook-basal body complex protein FliE
ASZ87_RS12670	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASZ87_RS12675	COG1317	bacterial-type flagellum organization
ASZ87_RS12700	COG1580	Controls the rotational direction of flagella during chemotaxis
ASZ87_RS12725	COG1987	bacterial-type flagellum assembly
ASZ87_RS12730	COG1684	flagellar biosynthetic protein fliR
ASZ87_RS12740	COG2840	Smr protein MutS2
ASZ87_RS12745	COG2890	protein-(glutamine-N5) methyltransferase activity
ASZ87_RS12755	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASZ87_RS12760	COG2860	membrane
ASZ87_RS12765	COG3101	peptidyl-lysine hydroxylation
ASZ87_RS12775	COG0431	NADPH-dependent FMN reductase
ASZ87_RS12785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASZ87_RS12790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASZ87_RS12795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASZ87_RS12800	COG0735	belongs to the Fur family
ASZ87_RS12810	COG0583	DNA-binding transcription factor activity
ASZ87_RS12820	COG1346	cytolysis
ASZ87_RS12835	COG0596	Alpha beta hydrolase
ASZ87_RS12840	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ASZ87_RS12845	COG0033	Phosphoglucomutase
ASZ87_RS12855	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASZ87_RS12860	COG0372	Belongs to the citrate synthase family
ASZ87_RS12865	COG2009	succinate dehydrogenase
ASZ87_RS12870	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ASZ87_RS12875	COG1053	succinate dehydrogenase
ASZ87_RS12885	COG0567	Dehydrogenase, E1 component
ASZ87_RS12890	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASZ87_RS12895	COG0045	succinate-CoA ligase (ADP-forming) activity
ASZ87_RS12905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASZ87_RS12910	COG1121	(ABC) transporter
ASZ87_RS12915	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ASZ87_RS12925	COG4977	sequence-specific DNA binding
ASZ87_RS12930	COG1918	ferrous iron import across plasma membrane
ASZ87_RS12950	COG0018	arginyl-trna synthetase
ASZ87_RS12960	COG1025	Belongs to the peptidase M16 family
ASZ87_RS12965	COG2062	phosphohistidine phosphatase, SixA
ASZ87_RS12995	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ASZ87_RS13000	COG0643	Histidine kinase
ASZ87_RS13000	COG2198	Histidine kinase
ASZ87_RS13000	COG0784	Response regulator, receiver
ASZ87_RS13005	COG2201	protein-glutamate methylesterase activity
ASZ87_RS13010	COG1192	Involved in chromosome partitioning
ASZ87_RS13020	COG0835	chemotaxis
ASZ87_RS13030	COG4133	protoheme IX ABC transporter activity
ASZ87_RS13035	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASZ87_RS13040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASZ87_RS13050	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ASZ87_RS13055	COG1138	Cytochrome C-type biogenesis protein
ASZ87_RS13060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASZ87_RS13065	COG4235	cytochrome complex assembly
ASZ87_RS13065	COG3088	subunit of a heme lyase
ASZ87_RS13075	COG2853	Lipoprotein
ASZ87_RS13095	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ASZ87_RS13100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASZ87_RS13105	COG0123	including yeast histone deacetylase and acetoin utilization protein
ASZ87_RS13120	COG3083	sulfuric ester hydrolase activity
ASZ87_RS13125	COG3082	Protein of unknown function (DUF1414)
ASZ87_RS13130	COG3081	Nucleoid-associated protein
ASZ87_RS13140	COG1757	Na H antiporter
ASZ87_RS13145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASZ87_RS13150	COG2095	MarC family integral membrane protein
ASZ87_RS13155	COG1012	belongs to the aldehyde dehydrogenase family
ASZ87_RS13155	COG1454	alcohol dehydrogenase
ASZ87_RS13170	COG0659	secondary active sulfate transmembrane transporter activity
ASZ87_RS13175	COG1530	ribonuclease E activity
ASZ87_RS13190	COG0564	pseudouridine synthase activity
ASZ87_RS13195	COG0424	maF-like protein
ASZ87_RS13200	COG1399	metal-binding, possibly nucleic acid-binding protein
ASZ87_RS13205	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASZ87_RS13210	COG0416	fatty acid biosynthetic process
ASZ87_RS13215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASZ87_RS13225	COG1028	Short-chain dehydrogenase reductase Sdr
ASZ87_RS13230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASZ87_RS13235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASZ87_RS13240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASZ87_RS13245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ASZ87_RS13250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASZ87_RS13260	COG0084	hydrolase, TatD family'
ASZ87_RS13265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASZ87_RS13265	COG1263	PTS System
ASZ87_RS13270	COG0733	neurotransmitter:sodium symporter activity
ASZ87_RS13280	COG4667	esterase of the alpha-beta hydrolase superfamily
ASZ87_RS13290	COG1940	carbohydrate kinase activity
ASZ87_RS13295	COG0784	Response regulator, receiver
ASZ87_RS13295	COG0835	chemotaxis
ASZ87_RS13310	COG2226	methyltransferase
ASZ87_RS13330	COG0676	glucose-6-phosphate 1-epimerase activity
ASZ87_RS13335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASZ87_RS13340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASZ87_RS13350	COG3139	Protein of unknown function (DUF1315)
ASZ87_RS13355	COG0252	asparaginase activity
ASZ87_RS13360	COG0616	signal peptide processing
ASZ87_RS13365	COG1902	pentaerythritol trinitrate reductase activity
ASZ87_RS13365	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASZ87_RS13370	COG0788	formyltetrahydrofolate deformylase activity
ASZ87_RS13380	COG1199	ATP-dependent helicase activity
ASZ87_RS13385	COG1214	PFAM Peptidase M22, glycoprotease
ASZ87_RS13400	COG0596	Alpha beta hydrolase
ASZ87_RS13405	COG0318	PFAM AMP-dependent synthetase and ligase
ASZ87_RS13410	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ASZ87_RS13430	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ASZ87_RS13435	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ASZ87_RS13440	COG0436	Aminotransferase
ASZ87_RS13445	COG1169	isochorismate synthase
ASZ87_RS13450	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ASZ87_RS13455	COG0596	Alpha beta hydrolase
ASZ87_RS13475	COG3135	benzoate transporter
ASZ87_RS13480	COG1396	sequence-specific DNA binding
ASZ87_RS13485	COG0840	transmembrane signaling receptor activity
ASZ87_RS13495	COG0477	Major facilitator Superfamily
ASZ87_RS13515	COG3015	lipoprotein NlpE involved in copper resistance
ASZ87_RS13520	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ASZ87_RS13525	COG2894	cell division
ASZ87_RS13530	COG0850	regulation of cytokinetic process
ASZ87_RS13535	COG3100	YcgL domain-containing protein
ASZ87_RS13540	COG2951	lytic endotransglycosylase activity
ASZ87_RS13550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASZ87_RS13555	COG3469	chitinase activity
ASZ87_RS13555	COG3325	Belongs to the glycosyl hydrolase 18 family
ASZ87_RS13560	COG3005	denitrification pathway
ASZ87_RS13565	COG0243	molybdopterin cofactor binding
ASZ87_RS13580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASZ87_RS13590	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASZ87_RS13630	COG4589	Belongs to the CDS family
ASZ87_RS13640	COG3300	MHYT domain
ASZ87_RS13640	COG5001	Diguanylate cyclase
ASZ87_RS13655	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ASZ87_RS13660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASZ87_RS13665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASZ87_RS13670	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASZ87_RS13680	COG4191	Histidine kinase
ASZ87_RS13690	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASZ87_RS13700	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASZ87_RS13705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASZ87_RS13710	COG0776	regulation of translation
ASZ87_RS13715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASZ87_RS13720	COG1555	photosystem II stabilization
ASZ87_RS13725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ASZ87_RS13730	COG0539	negative regulation of cytoplasmic translation
ASZ87_RS13735	COG0776	regulation of translation
ASZ87_RS13740	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ASZ87_RS13745	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ASZ87_RS13765	COG0583	DNA-binding transcription factor activity
ASZ87_RS13775	COG0686	Belongs to the AlaDH PNT family
ASZ87_RS13785	COG1674	ftsk spoiiie
ASZ87_RS13790	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ASZ87_RS13795	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASZ87_RS13800	COG2186	Transcriptional regulator
ASZ87_RS13815	COG0537	adenosine 5'-monophosphoramidase activity
ASZ87_RS13840	COG3150	esterase
ASZ87_RS13845	COG1252	NADH dehydrogenase
ASZ87_RS13865	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASZ87_RS13875	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASZ87_RS13880	COG1136	(ABC) transporter
ASZ87_RS13885	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASZ87_RS13895	COG0658	competence protein
ASZ87_RS13895	COG2333	competence protein COMEC
ASZ87_RS13900	COG1132	(ABC) transporter
ASZ87_RS13905	COG1663	tetraacyldisaccharide 4'-kinase activity
ASZ87_RS13910	COG2835	tetraacyldisaccharide 4'-kinase activity
ASZ87_RS13915	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ASZ87_RS13920	COG2719	SpoVR family
ASZ87_RS13925	COG2718	Belongs to the UPF0229 family
ASZ87_RS13930	COG2766	serine protein kinase
ASZ87_RS13935	COG3013	Belongs to the UPF0304 family
ASZ87_RS13945	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASZ87_RS13950	COG0840	transmembrane signaling receptor activity
ASZ87_RS13960	COG1882	Formate acetyltransferase
ASZ87_RS13985	COG4160	amino acid transport
ASZ87_RS13990	COG0708	Exodeoxyribonuclease III
ASZ87_RS13995	COG0840	transmembrane signaling receptor activity
ASZ87_RS14005	COG3923	Primosomal replication protein n
ASZ87_RS14010	COG0730	response to heat
ASZ87_RS14015	COG1199	ATP-dependent helicase activity
ASZ87_RS14020	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASZ87_RS14025	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ASZ87_RS14030	COG3012	SEC-C Motif Domain Protein
ASZ87_RS14035	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ASZ87_RS14040	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASZ87_RS14045	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ASZ87_RS14050	COG0215	cysteine-tRNA ligase activity
ASZ87_RS14055	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ASZ87_RS14060	COG0632	four-way junction helicase activity
ASZ87_RS14070	COG1271	oxidase subunit
ASZ87_RS14075	COG1294	oxidase, subunit
ASZ87_RS14080	COG4890	Cyd operon protein YbgT
ASZ87_RS14085	COG3790	cyd operon protein YbgE
ASZ87_RS14090	COG0824	Thioesterase
ASZ87_RS14095	COG0811	peptide transport
ASZ87_RS14110	COG0823	Involved in the tonB-independent uptake of proteins
ASZ87_RS14115	COG2885	chlorophyll binding
ASZ87_RS14125	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ASZ87_RS14135	COG5002	protein histidine kinase activity
ASZ87_RS14135	COG0784	Response regulator, receiver
ASZ87_RS14145	COG1482	cell wall glycoprotein biosynthetic process
ASZ87_RS14150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ87_RS14150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASZ87_RS14150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ87_RS14155	COG2207	Transcriptional regulator
ASZ87_RS14165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ87_RS14170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ87_RS14175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASZ87_RS14185	COG1012	belongs to the aldehyde dehydrogenase family
ASZ87_RS14190	COG3284	Transcriptional regulator
ASZ87_RS14195	COG4628	conserved protein (DUF2132)
ASZ87_RS14205	COG0415	Belongs to the DNA photolyase family
ASZ87_RS14290	COG0488	(ABC) transporter
ASZ87_RS14570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASZ87_RS14660	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ASZ87_RS14705	COG0612	Peptidase, M16
ASZ87_RS15165	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ASZ87_RS15240	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ASZ87_RS15260	COG2200	EAL domain
ASZ87_RS15655	COG3008	intermembrane lipid transfer
ASZ87_RS16670	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASZ87_RS16810	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASZ87_RS17015	COG4211	Belongs to the binding-protein-dependent transport system permease family
ASZ87_RS17095	COG3713	MltA-interacting MipA family protein
ASZ87_RS17100	COG3713	MltA-interacting MipA family protein
ASZ87_RS17305	COG1760	l-serine dehydratase
ASZ87_RS17310	COG1760	l-serine dehydratase
ASZ87_RS17345	COG0017	Asparaginyl-tRNA synthetase
ASZ87_RS17365	COG0351	phosphomethylpyrimidine kinase
ASZ87_RS17385	COG3437	response regulator, receiver
ASZ87_RS17385	COG2770	Histidine kinase
ASZ87_RS17470	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ASZ87_RS17820	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASZ87_RS17975	COG0322	excinuclease ABC activity
ASZ87_RS18170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASZ87_RS18310	COG0076	glutamate decarboxylase activity
ASZ87_RS18380	COG1187	pseudouridine synthase activity
ASZ87_RS18960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASZ87_RS19225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASZ87_RS19250	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ASZ87_RS19505	COG1611	Belongs to the LOG family
ASZ87_RS19535	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASZ87_RS19690	COG0443	Heat shock 70 kDa protein
ASZ87_RS19745	COG3064	Membrane
ASZ87_RS19750	COG3064	Membrane
ASZ87_RS20060	COG3290	protein histidine kinase activity
ASZ87_RS20115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASZ87_RS20155	COG0517	IMP dehydrogenase activity
ASZ87_RS20155	COG0516	GMP reductase activity