locus-tag	class	description
CSW01_RS00010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CSW01_RS00015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CSW01_RS00020	COG0706	membrane insertase activity
CSW01_RS00030	COG0594	ribonuclease P activity
CSW01_RS00035	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CSW01_RS00040	COG1126	abc transporter atp-binding protein
CSW01_RS00055	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CSW01_RS00060	COG0592	DNA-directed DNA polymerase activity
CSW01_RS00065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CSW01_RS00070	COG0187	DNA topoisomerase II activity
CSW01_RS00085	COG0071	Belongs to the small heat shock protein (HSP20) family
CSW01_RS00090	COG3977	Valine--pyruvate aminotransferase
CSW01_RS00100	COG0751	glycine-tRNA ligase activity
CSW01_RS00105	COG0752	glycyl-tRNA synthetase alpha subunit
CSW01_RS00110	COG2119	membrane
CSW01_RS00125	COG0425	Belongs to the sulfur carrier protein TusA family
CSW01_RS00135	COG0604	alcohol dehydrogenase
CSW01_RS00145	COG0129	dihydroxy-acid dehydratase activity
CSW01_RS00150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSW01_RS00165	COG0606	chelatase, subunit chli
CSW01_RS00170	COG0204	Acyl-transferase
CSW01_RS00175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CSW01_RS00180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CSW01_RS00195	COG3084	Protein conserved in bacteria
CSW01_RS00205	COG4326	sporulation control protein
CSW01_RS00210	COG1272	protein, Hemolysin III
CSW01_RS00220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSW01_RS00225	COG0569	domain protein
CSW01_RS00230	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CSW01_RS00230	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CSW01_RS00235	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CSW01_RS00240	COG0242	peptide deformylase activity
CSW01_RS00245	COG1652	LysM domain
CSW01_RS00250	COG0758	DNA mediated transformation
CSW01_RS00255	COG2922	Belongs to the Smg family
CSW01_RS00260	COG0551	DNA topoisomerase type I activity
CSW01_RS00265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CSW01_RS00270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CSW01_RS00275	COG0009	L-threonylcarbamoyladenylate synthase
CSW01_RS00280	COG0408	coproporphyrinogen oxidase activity
CSW01_RS00285	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CSW01_RS00295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CSW01_RS00335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CSW01_RS00340	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CSW01_RS00350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSW01_RS00355	COG2104	thiamine diphosphate biosynthetic process
CSW01_RS00360	COG2022	thiamine diphosphate biosynthetic process
CSW01_RS00365	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CSW01_RS00370	COG0006	proline dipeptidase activity
CSW01_RS00370	COG0006	proline dipeptidase activity
CSW01_RS00390	COG1522	sequence-specific DNA binding
CSW01_RS00395	COG5002	protein histidine kinase activity
CSW01_RS00395	COG5001	Diguanylate cyclase
CSW01_RS00415	COG0589	response to stress
CSW01_RS00425	COG1528	Iron-storage protein
CSW01_RS00435	COG2081	HI0933 family
CSW01_RS00445	COG1322	Protein conserved in bacteria
CSW01_RS00450	COG2226	methyltransferase
CSW01_RS00465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CSW01_RS00470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CSW01_RS00475	COG0805	protein transport
CSW01_RS00480	COG1858	cytochrome C peroxidase
CSW01_RS00485	COG0534	Mate efflux family protein
CSW01_RS00495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CSW01_RS00510	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CSW01_RS00515	COG3161	chorismate lyase activity
CSW01_RS00525	COG1580	Controls the rotational direction of flagella during chemotaxis
CSW01_RS00530	COG0840	transmembrane signaling receptor activity
CSW01_RS00540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW01_RS00550	COG0084	hydrolase, TatD family'
CSW01_RS00565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSW01_RS00565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSW01_RS00585	COG3078	GTPase activator activity
CSW01_RS00600	COG3071	HemY protein
CSW01_RS00605	COG2959	enzyme of heme biosynthesis
CSW01_RS00610	COG1587	Uroporphyrinogen-III synthase
CSW01_RS00615	COG0181	hydroxymethylbilane synthase activity
CSW01_RS00630	COG1965	Belongs to the frataxin family
CSW01_RS00640	COG0019	diaminopimelate decarboxylase activity
CSW01_RS00645	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CSW01_RS00655	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CSW01_RS00660	COG1011	Hydrolase
CSW01_RS00665	COG2199	diguanylate cyclase activity
CSW01_RS00665	COG2200	EAL domain
CSW01_RS00665	COG3287	FIST C domain
CSW01_RS00685	COG0561	phosphatase activity
CSW01_RS00690	COG2267	carboxylic ester hydrolase activity
CSW01_RS00695	COG1280	lysine exporter protein (LysE YggA)
CSW01_RS00700	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CSW01_RS00705	COG0783	Belongs to the Dps family
CSW01_RS00745	COG0742	ribosomal rna small subunit methyltransferase
CSW01_RS00750	COG0552	protein localization to endoplasmic reticulum
CSW01_RS00755	COG2884	Cell division ATP-binding protein ftsE
CSW01_RS00760	COG2177	Part of the ABC transporter FtsEX involved in
CSW01_RS00765	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CSW01_RS00770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSW01_RS00790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CSW01_RS00795	COG4206	TonB-dependent receptor
CSW01_RS00800	COG1404	Belongs to the peptidase S8 family
CSW01_RS00805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CSW01_RS00840	COG0583	DNA-binding transcription factor activity
CSW01_RS00845	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CSW01_RS00850	COG2960	long-chain fatty acid transporting porin activity
CSW01_RS00855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSW01_RS00860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSW01_RS00865	COG1309	transcriptional regulator
CSW01_RS00920	COG0747	negative chemotaxis
CSW01_RS00925	COG0601	transmembrane transport
CSW01_RS00930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSW01_RS00940	COG2131	deaminase
CSW01_RS00965	COG3621	Patatin-like phospholipase
CSW01_RS01005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSW01_RS01010	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CSW01_RS01020	COG0210	DNA helicase
CSW01_RS01035	COG1280	lysine exporter protein (LysE YggA)
CSW01_RS01050	COG2962	Rard protein
CSW01_RS01055	COG0514	ATP-dependent DNA helicase (RecQ)
CSW01_RS01070	COG1132	(ABC) transporter
CSW01_RS01075	COG4774	siderophore transport
CSW01_RS01080	COG1120	ATPase activity
CSW01_RS01105	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CSW01_RS01110	COG1263	PTS System
CSW01_RS01110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW01_RS01115	COG2862	Uncharacterized protein family, UPF0114
CSW01_RS01120	COG1561	YicC-like family, N-terminal region
CSW01_RS01125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CSW01_RS01130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CSW01_RS01135	COG1560	Kdo2-lipid A biosynthetic process
CSW01_RS01140	COG1560	Kdo2-lipid A biosynthetic process
CSW01_RS01145	COG1309	transcriptional regulator
CSW01_RS01155	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CSW01_RS01165	COG2003	Belongs to the UPF0758 family
CSW01_RS01170	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CSW01_RS01175	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CSW01_RS01185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CSW01_RS01190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CSW01_RS01195	COG0859	PFAM glycosyl transferase family 9
CSW01_RS01200	COG0463	Glycosyl transferase, family 2
CSW01_RS01205	COG0859	PFAM glycosyl transferase family 9
CSW01_RS01210	COG3642	lipopolysaccharide core region biosynthetic process
CSW01_RS01240	COG1519	Transferase
CSW01_RS01275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSW01_RS01280	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CSW01_RS01280	COG0662	Cupin 2, conserved barrel domain protein
CSW01_RS01285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSW01_RS01290	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CSW01_RS01320	COG0318	PFAM AMP-dependent synthetase and ligase
CSW01_RS01325	COG1012	belongs to the aldehyde dehydrogenase family
CSW01_RS01325	COG1454	alcohol dehydrogenase
CSW01_RS01375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSW01_RS01380	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CSW01_RS01385	COG0668	transmembrane transport
CSW01_RS01390	COG1573	uracil-dna glycosylase
CSW01_RS01400	COG3068	Protein conserved in bacteria
CSW01_RS01410	COG1940	carbohydrate kinase activity
CSW01_RS01415	COG1253	flavin adenine dinucleotide binding
CSW01_RS01420	COG0776	regulation of translation
CSW01_RS01430	COG0151	Belongs to the GarS family
CSW01_RS01445	COG0789	Transcriptional regulator
CSW01_RS01450	COG3710	Transcriptional regulator
CSW01_RS01455	COG0531	amino acid
CSW01_RS01460	COG1982	Orn Lys Arg decarboxylase major
CSW01_RS01465	COG0840	transmembrane signaling receptor activity
CSW01_RS01480	COG0800	Aldolase
CSW01_RS01490	COG3265	gluconokinase activity
CSW01_RS01495	COG0129	dihydroxy-acid dehydratase activity
CSW01_RS01500	COG1609	Transcriptional regulator
CSW01_RS01505	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CSW01_RS01510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSW01_RS01515	COG2264	protein methyltransferase activity
CSW01_RS01520	COG0439	Biotin carboxylase
CSW01_RS01525	COG0511	ligase activity, forming carbon-carbon bonds
CSW01_RS01530	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CSW01_RS01535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSW01_RS01555	COG2814	Major facilitator Superfamily
CSW01_RS01560	COG0784	Response regulator, receiver
CSW01_RS01560	COG2205	protein histidine kinase activity
CSW01_RS01565	COG0248	Ppx GppA phosphatase
CSW01_RS01570	COG0513	Belongs to the DEAD box helicase family
CSW01_RS01575	COG3118	belongs to the thioredoxin family
CSW01_RS01590	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CSW01_RS01635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSW01_RS01645	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CSW01_RS01655	COG1072	(Pantothenic acid kinase))
CSW01_RS01680	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CSW01_RS01685	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CSW01_RS01690	COG0250	Participates in transcription elongation, termination and antitermination
CSW01_RS01695	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CSW01_RS01705	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CSW01_RS01710	COG0222	ribosome binding
CSW01_RS01715	COG0085	RNA polymerase activity
CSW01_RS01720	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CSW01_RS01725	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CSW01_RS01730	COG2816	NAD+ diphosphatase activity
CSW01_RS01735	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CSW01_RS01750	COG4942	peptidase
CSW01_RS01755	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CSW01_RS01765	COG0471	metal ion transport
CSW01_RS01765	COG0490	domain, Protein
CSW01_RS01770	COG0688	phosphatidylethanolamine metabolic process
CSW01_RS01775	COG1162	GTPase activity
CSW01_RS01780	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CSW01_RS01825	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CSW01_RS01830	COG0802	atpase or kinase
CSW01_RS01840	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CSW01_RS01845	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CSW01_RS01850	COG1923	regulation of RNA biosynthetic process
CSW01_RS01855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CSW01_RS01860	COG0330	HflC and HflK could
CSW01_RS01865	COG0330	HflC and HflK could
CSW01_RS01870	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CSW01_RS01875	COG2900	Belongs to the SlyX family
CSW01_RS01885	COG0545	Peptidyl-prolyl cis-trans isomerase
CSW01_RS01890	COG2964	Protein conserved in bacteria
CSW01_RS01895	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CSW01_RS01900	COG2923	Belongs to the DsrF TusC family
CSW01_RS01915	COG0049	tRNA binding
CSW01_RS01920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CSW01_RS01925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CSW01_RS01930	COG2906	2 iron, 2 sulfur cluster binding
CSW01_RS01940	COG0360	Binds together with S18 to 16S ribosomal RNA
CSW01_RS01945	COG2965	DNA replication, synthesis of RNA primer
CSW01_RS01950	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CSW01_RS01955	COG0359	binds to the 23S rRNA
CSW01_RS01970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CSW01_RS01975	COG0432	Pfam Uncharacterised protein family UPF0047
CSW01_RS01995	COG0735	belongs to the Fur family
CSW01_RS02000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSW01_RS02025	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CSW01_RS02035	COG0175	sulfate reduction
CSW01_RS02075	COG1410	methionine synthase
CSW01_RS02075	COG0646	methionine synthase
CSW01_RS02080	COG0527	aspartate kinase activity
CSW01_RS02085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CSW01_RS02095	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CSW01_RS02110	COG0629	single-stranded DNA binding
CSW01_RS02115	COG2200	EAL domain
CSW01_RS02115	COG2199	diguanylate cyclase activity
CSW01_RS02140	COG3267	Type II secretory pathway component ExeA
CSW01_RS02140	COG3409	Peptidoglycan-binding domain 1 protein
CSW01_RS02150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CSW01_RS02155	COG1459	type II secretion system
CSW01_RS02165	COG2165	general secretion pathway protein
CSW01_RS02170	COG2165	general secretion pathway protein
CSW01_RS02200	COG1077	Cell shape determining protein MreB Mrl
CSW01_RS02205	COG1792	Involved in formation and maintenance of cell shape
CSW01_RS02210	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CSW01_RS02215	COG0424	maF-like protein
CSW01_RS02225	COG3164	Protein of unknown function
CSW01_RS02230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSW01_RS02235	COG0312	modulator of DNA gyrase
CSW01_RS02240	COG2235	arginine
CSW01_RS02260	COG0589	response to stress
CSW01_RS02270	COG2358	TRAP transporter, solute receptor (TAXI family
CSW01_RS02280	COG1438	arginine binding
CSW01_RS02285	COG0039	L-malate dehydrogenase activity
CSW01_RS02290	COG0531	amino acid
CSW01_RS02295	COG0142	geranyltranstransferase activity
CSW01_RS02300	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CSW01_RS02305	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CSW01_RS02310	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CSW01_RS02315	COG2966	Psort location CytoplasmicMembrane, score
CSW01_RS02320	COG3610	response to peptide
CSW01_RS02330	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CSW01_RS02335	COG2967	ApaG domain
CSW01_RS02340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CSW01_RS02345	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CSW01_RS02350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSW01_RS02355	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CSW01_RS02360	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CSW01_RS02415	COG0741	lytic transglycosylase activity
CSW01_RS02420	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CSW01_RS02425	COG1194	a g-specific adenine glycosylase
CSW01_RS02435	COG2066	Belongs to the glutaminase family
CSW01_RS02440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSW01_RS02445	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CSW01_RS02455	COG1872	DUF167
CSW01_RS02460	COG0762	integral membrane protein
CSW01_RS02465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CSW01_RS02470	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CSW01_RS02490	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CSW01_RS02495	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CSW01_RS02500	COG1678	Uncharacterized ACR, COG1678
CSW01_RS02505	COG0189	ligase activity
CSW01_RS02510	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSW01_RS02515	COG2356	endonuclease I
CSW01_RS02525	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CSW01_RS02530	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CSW01_RS02535	COG0583	DNA-binding transcription factor activity
CSW01_RS02540	COG4771	TonB-dependent receptor
CSW01_RS02545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSW01_RS02550	COG0126	phosphoglycerate kinase activity
CSW01_RS02555	COG0191	fructose-bisphosphate aldolase activity
CSW01_RS02565	COG0668	transmembrane transport
CSW01_RS02570	COG1279	arginine transmembrane transporter activity
CSW01_RS02595	COG1349	DNA-binding transcription factor activity
CSW01_RS02600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CSW01_RS02605	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CSW01_RS02655	COG0328	RNA-DNA hybrid ribonuclease activity
CSW01_RS02670	COG4969	Belongs to the N-Me-Phe pilin family
CSW01_RS02680	COG0739	heme binding
CSW01_RS02715	COG2003	Belongs to the UPF0758 family
CSW01_RS02725	COG0840	transmembrane signaling receptor activity
CSW01_RS02730	COG2207	Transcriptional regulator
CSW01_RS02735	COG0840	transmembrane signaling receptor activity
CSW01_RS02740	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CSW01_RS02745	COG0582	viral genome integration into host DNA
CSW01_RS02760	COG0358	DNA primase activity
CSW01_RS02765	COG1610	YqeY-like protein
CSW01_RS02770	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CSW01_RS02775	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CSW01_RS02785	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CSW01_RS02795	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CSW01_RS02800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CSW01_RS02805	COG1968	undecaprenyl-diphosphatase activity
CSW01_RS02810	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CSW01_RS02815	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CSW01_RS02820	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CSW01_RS02825	COG0585	pseudouridine synthase activity
CSW01_RS02830	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CSW01_RS02835	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CSW01_RS02845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CSW01_RS02850	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CSW01_RS02870	COG4208	sulfate ABC transporter
CSW01_RS02875	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CSW01_RS02885	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CSW01_RS02895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CSW01_RS02900	COG0527	aspartate kinase activity
CSW01_RS02905	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CSW01_RS02950	COG3630	sodium ion export across plasma membrane
CSW01_RS02955	COG0511	ligase activity, forming carbon-carbon bonds
CSW01_RS02955	COG5016	pyruvate
CSW01_RS02960	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CSW01_RS02970	COG1238	metal cluster binding
CSW01_RS02975	COG0612	Peptidase, M16
CSW01_RS02980	COG2918	glutathione biosynthetic process
CSW01_RS02985	COG1854	S-ribosylhomocysteine lyase activity
CSW01_RS02990	COG4536	flavin adenine dinucleotide binding
CSW01_RS02995	COG4137	Cytochrome C assembly protein
CSW01_RS03000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CSW01_RS03005	COG0228	four-way junction DNA binding
CSW01_RS03010	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CSW01_RS03015	COG0336	Belongs to the RNA methyltransferase TrmD family
CSW01_RS03020	COG0335	large ribosomal subunit rRNA binding
CSW01_RS03025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSW01_RS03030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSW01_RS03040	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CSW01_RS03045	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CSW01_RS03050	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CSW01_RS03055	COG0723	plastoquinol--plastocyanin reductase activity
CSW01_RS03060	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CSW01_RS03065	COG2857	Cytochrome c1
CSW01_RS03070	COG0625	glutathione transferase activity
CSW01_RS03075	COG2969	positive regulation of protein catabolic process
CSW01_RS03080	COG2823	Periplasmic or secreted lipoprotein
CSW01_RS03085	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CSW01_RS03090	COG0792	nuclease activity
CSW01_RS03095	COG3107	peptidoglycan biosynthetic process
CSW01_RS03100	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CSW01_RS03120	COG0288	reversible hydration of carbon dioxide
CSW01_RS03125	COG0659	secondary active sulfate transmembrane transporter activity
CSW01_RS03130	COG1131	(ABC) transporter
CSW01_RS03135	COG0842	Transport permease protein
CSW01_RS03140	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CSW01_RS03145	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CSW01_RS03150	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CSW01_RS03160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CSW01_RS03170	COG1489	DNA binding
CSW01_RS03180	COG1643	Atp-dependent helicase
CSW01_RS03185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSW01_RS03190	COG1752	Esterase of the alpha-beta hydrolase superfamily
CSW01_RS03195	COG1049	propionate catabolic process, 2-methylcitrate cycle
CSW01_RS03200	COG3112	Uncharacterised protein family (UPF0231)
CSW01_RS03205	COG0347	Belongs to the P(II) protein family
CSW01_RS03210	COG0004	ammonium transporteR
CSW01_RS03215	COG1840	ABC-type Fe3 transport system, periplasmic component
CSW01_RS03225	COG3842	ATPase activity
CSW01_RS03245	COG2971	BadF BadG BcrA BcrD
CSW01_RS03255	COG4608	Belongs to the ABC transporter superfamily
CSW01_RS03260	COG0444	Belongs to the ABC transporter superfamily
CSW01_RS03265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSW01_RS03270	COG0601	transmembrane transport
CSW01_RS03275	COG0747	negative chemotaxis
CSW01_RS03285	COG2205	protein histidine kinase activity
CSW01_RS03285	COG0784	Response regulator, receiver
CSW01_RS03290	COG2813	Specifically methylates the guanine in position
CSW01_RS03295	COG0628	permease
CSW01_RS03300	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CSW01_RS03305	COG0316	Belongs to the HesB IscA family
CSW01_RS03320	COG0739	heme binding
CSW01_RS03325	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CSW01_RS03330	COG2027	D-alanyl-D-alanine carboxypeptidase
CSW01_RS03335	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CSW01_RS03340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CSW01_RS03345	COG1534	Rna-binding protein
CSW01_RS03350	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CSW01_RS03355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSW01_RS03360	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CSW01_RS03375	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CSW01_RS03390	COG0779	Required for maturation of 30S ribosomal subunits
CSW01_RS03395	COG0195	Participates in both transcription termination and antitermination
CSW01_RS03400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CSW01_RS03405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CSW01_RS03415	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CSW01_RS03440	COG0826	peptidase U32
CSW01_RS03445	COG0826	peptidase U32
CSW01_RS03455	COG3154	lipid carrier protein
CSW01_RS03460	COG3153	acetyltransferase
CSW01_RS03485	COG0513	Belongs to the DEAD box helicase family
CSW01_RS03505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CSW01_RS03510	COG2204	response regulator
CSW01_RS03520	COG0667	Aldo Keto reductase
CSW01_RS03530	COG0494	nUDIX hydrolase
CSW01_RS03535	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CSW01_RS03540	COG0730	response to heat
CSW01_RS03545	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CSW01_RS03555	COG1283	sodium-dependent phosphate transmembrane transporter activity
CSW01_RS03560	COG0583	DNA-binding transcription factor activity
CSW01_RS03565	COG0640	Transcriptional regulator
CSW01_RS03570	COG0268	Binds directly to 16S ribosomal RNA
CSW01_RS03575	COG0728	peptidoglycan biosynthetic process
CSW01_RS03580	COG0196	riboflavin kinase activity
CSW01_RS03595	COG1047	Peptidyl-prolyl cis-trans
CSW01_RS03600	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CSW01_RS03605	COG1966	Carbon starvation protein
CSW01_RS03620	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CSW01_RS03625	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CSW01_RS03635	COG3279	Response regulator of the LytR AlgR family
CSW01_RS03640	COG3275	phosphorelay sensor kinase activity
CSW01_RS03645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CSW01_RS03650	COG1605	Chorismate mutase
CSW01_RS03650	COG0287	Prephenate dehydrogenase
CSW01_RS03660	COG0488	(ABC) transporter
CSW01_RS03670	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CSW01_RS03680	COG5001	Diguanylate cyclase
CSW01_RS03685	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CSW01_RS03690	COG0077	Prephenate dehydratase
CSW01_RS03690	COG1605	Chorismate mutase
CSW01_RS03695	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CSW01_RS03700	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSW01_RS03705	COG0564	pseudouridine synthase activity
CSW01_RS03715	COG0542	response to heat
CSW01_RS03755	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSW01_RS03760	COG0826	peptidase U32
CSW01_RS03770	COG0745	RESPONSE REGULATOR receiver
CSW01_RS03775	COG5002	protein histidine kinase activity
CSW01_RS03785	COG0248	Ppx GppA phosphatase
CSW01_RS03790	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CSW01_RS03800	COG0581	inorganic phosphate transmembrane transporter activity
CSW01_RS03805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CSW01_RS03820	COG3142	Participates in the control of copper homeostasis
CSW01_RS03825	COG0450	alkyl hydroperoxide reductase
CSW01_RS03830	COG0583	DNA-binding transcription factor activity
CSW01_RS03835	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CSW01_RS03845	COG0517	IMP dehydrogenase activity
CSW01_RS03865	COG1862	Preprotein translocase
CSW01_RS03870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSW01_RS03875	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSW01_RS03880	COG0483	inositol monophosphate 1-phosphatase activity
CSW01_RS03890	COG1959	2 iron, 2 sulfur cluster binding
CSW01_RS03895	COG1104	cysteine desulfurase activity
CSW01_RS03900	COG0822	iron-sulfur transferase activity
CSW01_RS03910	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CSW01_RS03915	COG0443	Heat shock 70 kDa protein
CSW01_RS03920	COG0633	Ferredoxin
CSW01_RS03925	COG2975	iron-sulfur cluster assembly
CSW01_RS03930	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CSW01_RS03935	COG0105	UTP biosynthetic process
CSW01_RS03940	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CSW01_RS03950	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CSW01_RS03955	COG0124	histidyl-tRNA synthetase
CSW01_RS03960	COG2976	Protein conserved in bacteria
CSW01_RS03965	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSW01_RS03970	COG1160	GTP binding
CSW01_RS03985	COG1570	exodeoxyribonuclease VII activity
CSW01_RS03990	COG0517	IMP dehydrogenase activity
CSW01_RS03990	COG0516	GMP reductase activity
CSW01_RS03995	COG0519	Catalyzes the synthesis of GMP from XMP
CSW01_RS03995	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CSW01_RS04005	COG1584	GPR1 FUN34 yaaH family protein
CSW01_RS04010	COG1535	isochorismatase
CSW01_RS04010	COG3433	isochorismatase activity
CSW01_RS04015	COG1021	2,3-dihydroxybenzoate-AMP ligase
CSW01_RS04020	COG1169	isochorismate synthase
CSW01_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
CSW01_RS04035	COG4592	Periplasmic binding protein
CSW01_RS04040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW01_RS04045	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW01_RS04050	COG1120	ATPase activity
CSW01_RS04060	COG0583	DNA-binding transcription factor activity
CSW01_RS04065	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CSW01_RS04070	COG1115	amino acid carrier protein
CSW01_RS04080	COG0583	DNA-binding transcription factor activity
CSW01_RS04095	COG4565	transcriptional regulatory protein
CSW01_RS04105	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CSW01_RS04110	COG5016	pyruvate
CSW01_RS04110	COG0511	ligase activity, forming carbon-carbon bonds
CSW01_RS04115	COG3630	sodium ion export across plasma membrane
CSW01_RS04125	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CSW01_RS04135	COG2301	Belongs to the HpcH HpaI aldolase family
CSW01_RS04140	COG3051	citrate lyase alpha subunit
CSW01_RS04160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSW01_RS04165	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CSW01_RS04170	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CSW01_RS04235	COG1012	belongs to the aldehyde dehydrogenase family
CSW01_RS04255	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CSW01_RS04260	COG0840	transmembrane signaling receptor activity
CSW01_RS04265	COG3710	Transcriptional regulator
CSW01_RS04275	COG2165	general secretion pathway protein
CSW01_RS04290	COG4796	Type ii and iii secretion system protein
CSW01_RS04310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CSW01_RS04315	COG1459	type II secretion system
CSW01_RS04325	COG2207	Transcriptional regulator
CSW01_RS04330	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CSW01_RS04335	COG0840	transmembrane signaling receptor activity
CSW01_RS04350	COG0739	heme binding
CSW01_RS04360	COG3064	Membrane
CSW01_RS04365	COG0582	viral genome integration into host DNA
CSW01_RS04375	COG0582	viral genome integration into host DNA
CSW01_RS04385	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CSW01_RS04390	COG2867	negative regulation of translational initiation
CSW01_RS04395	COG2914	Belongs to the UPF0125 (RnfH) family
CSW01_RS04400	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSW01_RS04405	COG0497	DNA recombination
CSW01_RS04410	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CSW01_RS04415	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CSW01_RS04420	COG0443	Heat shock 70 kDa protein
CSW01_RS04425	COG0484	heat shock protein binding
CSW01_RS04435	COG4968	Prepilin-type N-terminal cleavage methylation domain
CSW01_RS04460	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CSW01_RS04470	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CSW01_RS04480	COG0047	phosphoribosylformylglycinamidine synthase activity
CSW01_RS04480	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSW01_RS04510	COG0442	prolyl-tRNA aminoacylation
CSW01_RS04515	COG1720	tRNA m6t6A37 methyltransferase activity
CSW01_RS04520	COG0254	rRNA binding
CSW01_RS04525	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CSW01_RS04530	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CSW01_RS04535	COG1671	Belongs to the UPF0178 family
CSW01_RS04545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW01_RS04560	COG3098	single-species biofilm formation
CSW01_RS04565	COG0564	pseudouridine synthase activity
CSW01_RS04570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CSW01_RS04575	COG0142	geranyltranstransferase activity
CSW01_RS04580	COG1722	exodeoxyribonuclease VII activity
CSW01_RS04585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CSW01_RS04595	COG0301	tRNA thio-modification
CSW01_RS04595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW01_RS04600	COG0583	DNA-binding transcription factor activity
CSW01_RS04605	COG2363	Small membrane protein
CSW01_RS04610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSW01_RS04615	COG1611	Belongs to the LOG family
CSW01_RS04630	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CSW01_RS04630	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CSW01_RS04640	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CSW01_RS04645	COG1464	Belongs to the NlpA lipoprotein family
CSW01_RS04650	COG2011	ABC-type metal ion transport system permease component
CSW01_RS04655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSW01_RS04660	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CSW01_RS04665	COG1609	Transcriptional regulator
CSW01_RS04670	COG1263	PTS System
CSW01_RS04670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW01_RS04675	COG0366	Alpha amylase catalytic
CSW01_RS04705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSW01_RS04710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CSW01_RS04715	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CSW01_RS04720	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CSW01_RS04725	COG0110	maltose O-acetyltransferase activity
CSW01_RS04745	COG1045	serine acetyltransferase
CSW01_RS04755	COG0438	transferase activity, transferring glycosyl groups
CSW01_RS04765	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CSW01_RS04795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSW01_RS04805	COG1596	polysaccharide export
CSW01_RS04830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CSW01_RS04840	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CSW01_RS04845	COG0321	lipoyl(octanoyl) transferase activity
CSW01_RS04850	COG2921	Belongs to the UPF0250 family
CSW01_RS04855	COG1686	Belongs to the peptidase S11 family
CSW01_RS04860	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CSW01_RS04865	COG0772	Belongs to the SEDS family
CSW01_RS04870	COG0768	penicillin binding
CSW01_RS04875	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CSW01_RS04880	COG0799	negative regulation of ribosome biogenesis
CSW01_RS04885	COG1466	dna polymerase III delta subunit
CSW01_RS04890	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CSW01_RS04895	COG0495	leucyl-tRNA aminoacylation
CSW01_RS04900	COG2888	peptidyl-tyrosine sulfation
CSW01_RS04905	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CSW01_RS04910	COG4535	Mg2 and Co2 transporter CorC
CSW01_RS04920	COG1702	phosphate starvation-inducible protein PhoH
CSW01_RS04925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CSW01_RS04930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSW01_RS04935	COG2190	(PTS) system
CSW01_RS04945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSW01_RS04955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSW01_RS04960	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CSW01_RS04965	COG3115	cell septum assembly
CSW01_RS04970	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CSW01_RS04990	COG0789	Transcriptional regulator
CSW01_RS04995	COG1585	Membrane protein implicated in regulation of membrane protease activity
CSW01_RS05000	COG0330	HflC and HflK could
CSW01_RS05010	COG3118	belongs to the thioredoxin family
CSW01_RS05015	COG0300	oxidoreductase activity
CSW01_RS05020	COG1090	epimerase
CSW01_RS05025	COG0622	Phosphoesterase
CSW01_RS05040	COG3710	Transcriptional regulator
CSW01_RS05045	COG0326	Molecular chaperone. Has ATPase activity
CSW01_RS05050	COG0563	adenylate kinase activity
CSW01_RS05055	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CSW01_RS05070	COG0367	asparagine synthase
CSW01_RS05075	COG4651	solute:proton antiporter activity
CSW01_RS05075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSW01_RS05080	COG1940	carbohydrate kinase activity
CSW01_RS05080	COG1846	Transcriptional regulator
CSW01_RS05085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CSW01_RS05090	COG2190	(PTS) system
CSW01_RS05090	COG1263	PTS System
CSW01_RS05090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW01_RS05105	COG0101	tRNA pseudouridine synthase activity
CSW01_RS05110	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CSW01_RS05115	COG0285	dihydrofolate synthase activity
CSW01_RS05120	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CSW01_RS05125	COG1286	toxin biosynthetic process
CSW01_RS05130	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CSW01_RS05135	COG2056	Na+-H+ antiporter family
CSW01_RS05140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSW01_RS05155	COG0346	lactoylglutathione lyase activity
CSW01_RS05160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CSW01_RS05180	COG4656	Part of a membrane complex involved in electron transport
CSW01_RS05185	COG2878	Part of a membrane complex involved in electron transport
CSW01_RS05190	COG4657	Part of a membrane complex involved in electron transport
CSW01_RS05200	COG0556	nucleotide-excision repair
CSW01_RS05210	COG2204	response regulator
CSW01_RS05215	COG2198	Histidine kinase
CSW01_RS05220	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CSW01_RS05225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CSW01_RS05230	COG0521	Mo-molybdopterin cofactor biosynthetic process
CSW01_RS05235	COG0315	cyclic pyranopterin monophosphate synthase activity
CSW01_RS05240	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CSW01_RS05245	COG0314	molybdopterin synthase activity
CSW01_RS05250	COG2199	diguanylate cyclase activity
CSW01_RS05255	COG0617	tRNA 3'-terminal CCA addition
CSW01_RS05255	COG0517	IMP dehydrogenase activity
CSW01_RS05255	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CSW01_RS05270	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CSW01_RS05280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSW01_RS05280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSW01_RS05285	COG0489	protein tyrosine kinase activity
CSW01_RS05295	COG0572	uridine kinase
CSW01_RS05300	COG2982	Protein involved in outer membrane biogenesis
CSW01_RS05305	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CSW01_RS05310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CSW01_RS05320	COG2067	long-chain fatty acid transport protein
CSW01_RS05340	COG0183	Belongs to the thiolase family
CSW01_RS05345	COG1024	Enoyl-CoA hydratase
CSW01_RS05345	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSW01_RS05350	COG0778	Nitroreductase
CSW01_RS05355	COG0583	DNA-binding transcription factor activity
CSW01_RS05360	COG0745	RESPONSE REGULATOR receiver
CSW01_RS05370	COG2832	Protein of unknown function (DUF454)
CSW01_RS05375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CSW01_RS05385	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CSW01_RS05390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CSW01_RS05400	COG2983	Belongs to the UPF0260 family
CSW01_RS05405	COG1028	Short-chain dehydrogenase reductase Sdr
CSW01_RS05410	COG0616	signal peptide processing
CSW01_RS05420	COG1522	sequence-specific DNA binding
CSW01_RS05425	COG1946	Acyl-CoA thioesterase
CSW01_RS05445	COG3706	GGDEF domain
CSW01_RS05455	COG0640	Transcriptional regulator
CSW01_RS05460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSW01_RS05485	COG1881	PFAM PEBP family protein
CSW01_RS05505	COG0009	L-threonylcarbamoyladenylate synthase
CSW01_RS05520	COG2201	protein-glutamate methylesterase activity
CSW01_RS05530	COG5002	protein histidine kinase activity
CSW01_RS05535	COG4191	Histidine kinase
CSW01_RS05540	COG5001	Diguanylate cyclase
CSW01_RS05540	COG3300	MHYT domain
CSW01_RS05545	COG2204	response regulator
CSW01_RS05565	COG0601	transmembrane transport
CSW01_RS05570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSW01_RS05575	COG0444	Belongs to the ABC transporter superfamily
CSW01_RS05580	COG4608	Belongs to the ABC transporter superfamily
CSW01_RS05585	COG0435	Glutathione S-transferase
CSW01_RS05590	COG0280	phosphate acetyltransferase
CSW01_RS05590	COG0857	belongs to the CobB CobQ family
CSW01_RS05595	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CSW01_RS05600	COG3092	negative regulation of chromosome organization
CSW01_RS05605	COG4628	conserved protein (DUF2132)
CSW01_RS05615	COG4120	Belongs to the binding-protein-dependent transport system permease family
CSW01_RS05625	COG2199	diguanylate cyclase activity
CSW01_RS05625	COG2203	Gaf domain
CSW01_RS05630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSW01_RS05640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CSW01_RS05645	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CSW01_RS05650	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CSW01_RS05655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSW01_RS05660	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CSW01_RS05665	COG0156	8-amino-7-oxononanoate synthase activity
CSW01_RS05670	COG2226	methyltransferase
CSW01_RS05675	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CSW01_RS05685	COG0501	Belongs to the peptidase M48B family
CSW01_RS05695	COG0300	oxidoreductase activity
CSW01_RS05710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CSW01_RS05720	COG2268	Band 7 protein
CSW01_RS05730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CSW01_RS05735	COG2915	High frequency lysogenization protein hflD homolog
CSW01_RS05740	COG0482	sulfurtransferase activity
CSW01_RS05745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSW01_RS05750	COG2916	Histone family protein nucleoid-structuring protein H-NS
CSW01_RS05755	COG1757	Na H antiporter
CSW01_RS05760	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CSW01_RS05765	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CSW01_RS05770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CSW01_RS05775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CSW01_RS05775	COG0131	Imidazoleglycerol-phosphate dehydratase
CSW01_RS05780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CSW01_RS05785	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CSW01_RS05790	COG0107	imidazoleglycerol-phosphate synthase activity
CSW01_RS05795	COG0140	phosphoribosyl-ATP diphosphatase activity
CSW01_RS05795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CSW01_RS05800	COG1187	pseudouridine synthase activity
CSW01_RS05810	COG1278	Cold shock
CSW01_RS05815	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CSW01_RS05820	COG0542	response to heat
CSW01_RS05825	COG3273	potassium ion transport
CSW01_RS05825	COG2985	domain, Protein
CSW01_RS05830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CSW01_RS05835	COG1454	alcohol dehydrogenase
CSW01_RS05835	COG1012	belongs to the aldehyde dehydrogenase family
CSW01_RS05840	COG1737	Transcriptional regulator
CSW01_RS05845	COG0076	glutamate decarboxylase activity
CSW01_RS05855	COG2431	L-lysine efflux transmembrane transporter activity
CSW01_RS05865	COG3070	regulator of competence-specific genes
CSW01_RS05880	COG3852	Histidine kinase
CSW01_RS05890	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CSW01_RS05910	COG0500	methyltransferase
CSW01_RS05915	COG4106	trans-aconitate 2-methyltransferase activity
CSW01_RS05920	COG1801	Protein of unknown function DUF72
CSW01_RS05925	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CSW01_RS05930	COG1435	thymidine kinase activity
CSW01_RS05940	COG0159	tryptophan synthase activity
CSW01_RS05945	COG0133	tryptophan synthase activity
CSW01_RS05950	COG0134	indole-3-glycerol-phosphate synthase activity
CSW01_RS05950	COG0135	phosphoribosylanthranilate isomerase activity
CSW01_RS05955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CSW01_RS05960	COG0512	Glutamine amidotransferase of anthranilate synthase
CSW01_RS05965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSW01_RS05975	COG0613	PHP domain protein
CSW01_RS05980	COG0009	L-threonylcarbamoyladenylate synthase
CSW01_RS05985	COG1187	pseudouridine synthase activity
CSW01_RS05990	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CSW01_RS05995	COG4988	ABC transporter
CSW01_RS06000	COG0492	ferredoxin-NADP+ reductase activity
CSW01_RS06010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CSW01_RS06015	COG3706	GGDEF domain
CSW01_RS06020	COG2949	membrane
CSW01_RS06030	COG0281	malic enzyme
CSW01_RS06040	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CSW01_RS06060	COG2885	chlorophyll binding
CSW01_RS06075	COG0247	lactate metabolic process
CSW01_RS06075	COG0277	FAD linked oxidase domain protein
CSW01_RS06095	COG2986	histidine ammonia-lyase
CSW01_RS06100	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CSW01_RS06105	COG0010	Belongs to the arginase family
CSW01_RS06110	COG1228	amidohydrolase
CSW01_RS06125	COG3099	Belongs to the UPF0263 family
CSW01_RS06130	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CSW01_RS06140	COG5001	Diguanylate cyclase
CSW01_RS06145	COG0417	DNA replication proofreading
CSW01_RS06150	COG2197	response regulator
CSW01_RS06155	COG0322	excinuclease ABC activity
CSW01_RS06195	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CSW01_RS06200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSW01_RS06200	COG0072	phenylalanine-tRNA ligase activity
CSW01_RS06205	COG0776	regulation of translation
CSW01_RS06245	COG1346	cytolysis
CSW01_RS06250	COG1380	Effector of murein hydrolase LrgA
CSW01_RS06255	COG2925	Exonuclease
CSW01_RS06260	COG1823	symporter activity
CSW01_RS06265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CSW01_RS06275	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CSW01_RS06280	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CSW01_RS06300	COG4139	cobalamin transport
CSW01_RS06355	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSW01_RS06360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSW01_RS06365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CSW01_RS06375	COG1054	Belongs to the UPF0176 family
CSW01_RS06385	COG2814	Major facilitator Superfamily
CSW01_RS06395	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CSW01_RS06420	COG2989	Protein conserved in bacteria
CSW01_RS06425	COG3108	Peptidase M15
CSW01_RS06430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW01_RS06445	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CSW01_RS06475	COG1846	Transcriptional regulator
CSW01_RS06480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSW01_RS06485	COG0726	polysaccharide deacetylase
CSW01_RS06490	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSW01_RS06500	COG1447	Phosphotransferase system cellobiose-specific component IIA
CSW01_RS06505	COG1486	melibiose metabolic process
CSW01_RS06515	COG1609	Transcriptional regulator
CSW01_RS06520	COG2943	transferase activity, transferring hexosyl groups
CSW01_RS06525	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CSW01_RS06530	COG0840	transmembrane signaling receptor activity
CSW01_RS06545	COG1448	Aminotransferase
CSW01_RS06555	COG3437	response regulator, receiver
CSW01_RS06555	COG2770	Histidine kinase
CSW01_RS06560	COG0351	phosphomethylpyrimidine kinase
CSW01_RS06565	COG0017	Asparaginyl-tRNA synthetase
CSW01_RS06575	COG0720	synthase
CSW01_RS06580	COG1760	l-serine dehydratase
CSW01_RS06585	COG0814	amino acid
CSW01_RS06590	COG0494	nUDIX hydrolase
CSW01_RS06595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSW01_RS06610	COG3106	COG3106 Predicted ATPase
CSW01_RS06615	COG3768	UPF0283 membrane protein
CSW01_RS06625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW01_RS06645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CSW01_RS06655	COG0471	metal ion transport
CSW01_RS06660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW01_RS06660	COG4191	Histidine kinase
CSW01_RS06670	COG2990	Protein conserved in bacteria
CSW01_RS06675	COG3713	MltA-interacting MipA family protein
CSW01_RS06680	COG2205	protein histidine kinase activity
CSW01_RS06685	COG0745	RESPONSE REGULATOR receiver
CSW01_RS06715	COG1129	ABC transporter
CSW01_RS06755	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CSW01_RS06760	COG0372	Belongs to the citrate synthase family
CSW01_RS06790	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSW01_RS06800	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CSW01_RS06810	COG0625	glutathione transferase activity
CSW01_RS06815	COG3437	response regulator, receiver
CSW01_RS06835	COG3706	GGDEF domain
CSW01_RS06840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CSW01_RS06845	COG1254	Belongs to the acylphosphatase family
CSW01_RS06850	COG2920	part of a sulfur-relay system
CSW01_RS06855	COG0670	Belongs to the BI1 family
CSW01_RS06860	COG1126	abc transporter atp-binding protein
CSW01_RS06865	COG0765	amino acid transport
CSW01_RS06870	COG4597	amino acid ABC transporter
CSW01_RS06875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW01_RS06885	COG0561	phosphatase activity
CSW01_RS06890	COG0602	queuosine metabolic process
CSW01_RS06895	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CSW01_RS06925	COG3706	GGDEF domain
CSW01_RS06930	COG0443	Heat shock 70 kDa protein
CSW01_RS06935	COG0443	Heat shock 70 kDa protein
CSW01_RS06970	COG1643	Atp-dependent helicase
CSW01_RS06980	COG0443	Heat shock 70 kDa protein
CSW01_RS06985	COG0095	Lipoate-protein ligase
CSW01_RS06995	COG0583	DNA-binding transcription factor activity
CSW01_RS07000	COG0477	Major facilitator Superfamily
CSW01_RS07005	COG0415	Belongs to the DNA photolyase family
CSW01_RS07020	COG0745	RESPONSE REGULATOR receiver
CSW01_RS07030	COG2198	Histidine kinase
CSW01_RS07030	COG0643	Histidine kinase
CSW01_RS07035	COG0784	Response regulator, receiver
CSW01_RS07035	COG0643	Histidine kinase
CSW01_RS07035	COG2198	Histidine kinase
CSW01_RS07040	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CSW01_RS07050	COG2201	protein-glutamate methylesterase activity
CSW01_RS07055	COG0835	chemotaxis
CSW01_RS07060	COG0840	transmembrane signaling receptor activity
CSW01_RS07060	COG3290	protein histidine kinase activity
CSW01_RS07065	COG0840	transmembrane signaling receptor activity
CSW01_RS07075	COG0513	Belongs to the DEAD box helicase family
CSW01_RS07085	COG1538	Outer membrane efflux protein
CSW01_RS07090	COG1566	PFAM secretion protein HlyD family protein
CSW01_RS07095	COG2814	Major facilitator Superfamily
CSW01_RS07105	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CSW01_RS07115	COG3501	Rhs element vgr protein
CSW01_RS07125	COG3675	Pfam Lipase (class 3)
CSW01_RS07140	COG1280	lysine exporter protein (LysE YggA)
CSW01_RS07145	COG1115	amino acid carrier protein
CSW01_RS07160	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CSW01_RS07170	COG1177	transmembrane transport
CSW01_RS07180	COG3842	ATPase activity
CSW01_RS07205	COG0589	response to stress
CSW01_RS07210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSW01_RS07225	COG2217	Heavy metal translocating P-type atpase
CSW01_RS07235	COG2010	Cytochrome c
CSW01_RS07250	COG3278	Belongs to the heme-copper respiratory oxidase family
CSW01_RS07265	COG0784	Response regulator, receiver
CSW01_RS07265	COG2205	protein histidine kinase activity
CSW01_RS07290	COG2994	toxin metabolic process
CSW01_RS07295	COG3064	Membrane
CSW01_RS07295	COG1073	alpha beta
CSW01_RS07295	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CSW01_RS07315	COG1476	TRANSCRIPTIONal
CSW01_RS07335	COG4128	Pfam Zonular occludens toxin
CSW01_RS07365	COG1476	TRANSCRIPTIONal
CSW01_RS07465	COG3120	sequence-specific DNA binding
CSW01_RS07470	COG1067	ATP-dependent peptidase activity
CSW01_RS07475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CSW01_RS07490	COG0488	(ABC) transporter
CSW01_RS07500	COG0116	Belongs to the methyltransferase superfamily
CSW01_RS07500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CSW01_RS07510	COG0167	dihydroorotate dehydrogenase activity
CSW01_RS07525	COG0308	aminopeptidase N
CSW01_RS07540	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CSW01_RS07545	COG1956	GAF domain-containing protein
CSW01_RS07550	COG1132	(ABC) transporter
CSW01_RS07555	COG2995	paraquat-inducible protein a
CSW01_RS07560	COG3008	intermembrane lipid transfer
CSW01_RS07570	COG2996	Protein conserved in bacteria
CSW01_RS07585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CSW01_RS07590	COG1666	GTP binding
CSW01_RS07595	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CSW01_RS07610	COG0437	4 iron, 4 sulfur cluster binding
CSW01_RS07615	COG3383	formate dehydrogenase (NAD+) activity
CSW01_RS07615	COG0243	molybdopterin cofactor binding
CSW01_RS07645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CSW01_RS07650	COG0488	(ABC) transporter
CSW01_RS07655	COG3852	Histidine kinase
CSW01_RS07660	COG2204	response regulator
CSW01_RS07670	COG4662	Binding-protein-dependent transport system inner membrane component
CSW01_RS07675	COG3842	ATPase activity
CSW01_RS07680	COG0746	molybdenum cofactor guanylyltransferase activity
CSW01_RS07715	COG1940	carbohydrate kinase activity
CSW01_RS07720	COG3148	PFAM DTW domain containing protein
CSW01_RS07730	COG0840	transmembrane signaling receptor activity
CSW01_RS07735	COG0791	NLP P60 protein
CSW01_RS07745	COG3001	Fructosamine kinase
CSW01_RS07755	COG0534	Mate efflux family protein
CSW01_RS07765	COG1793	dna ligase
CSW01_RS07780	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CSW01_RS07785	COG0848	biopolymer transport protein
CSW01_RS07790	COG0811	peptide transport
CSW01_RS07795	COG0811	peptide transport
CSW01_RS07810	COG1175	transmembrane transport
CSW01_RS07815	COG0395	ABC-type sugar transport system, permease component
CSW01_RS07820	COG3842	ATPase activity
CSW01_RS07825	COG1349	DNA-binding transcription factor activity
CSW01_RS07830	COG0584	glycerophosphoryl diester phosphodiesterase
CSW01_RS07835	COG2731	YhcH YjgK YiaL family protein
CSW01_RS07840	COG0251	oxidation-reduction process
CSW01_RS07845	COG1609	Transcriptional regulator
CSW01_RS07850	COG2723	6-phospho-beta-galactosidase activity
CSW01_RS07860	COG0583	DNA-binding transcription factor activity
CSW01_RS07880	COG1136	(ABC) transporter
CSW01_RS07880	COG0577	efflux transmembrane transporter activity
CSW01_RS07885	COG0577	efflux transmembrane transporter activity
CSW01_RS07885	COG1136	(ABC) transporter
CSW01_RS07890	COG1136	(ABC) transporter
CSW01_RS07890	COG4591	ABC-type transport system involved in lipoprotein release permease component
CSW01_RS07895	COG1294	oxidase, subunit
CSW01_RS07900	COG1271	oxidase subunit
CSW01_RS07945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSW01_RS07955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSW01_RS07975	COG0753	catalase activity
CSW01_RS07990	COG3527	Alpha-acetolactate decarboxylase
CSW01_RS08005	COG2199	diguanylate cyclase activity
CSW01_RS08005	COG2200	EAL domain
CSW01_RS08015	COG2017	converts alpha-aldose to the beta-anomer
CSW01_RS08020	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CSW01_RS08025	COG1085	galactose-1-phosphate uridylyltransferase
CSW01_RS08070	COG0835	chemotaxis
CSW01_RS08070	COG0784	Response regulator, receiver
CSW01_RS08080	COG4565	transcriptional regulatory protein
CSW01_RS08085	COG3290	protein histidine kinase activity
CSW01_RS08100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSW01_RS08120	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CSW01_RS08125	COG3063	Type IV pilus biogenesis stability protein PilW
CSW01_RS08135	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CSW01_RS08140	COG1451	nucleotide metabolic process
CSW01_RS08150	COG0583	DNA-binding transcription factor activity
CSW01_RS08170	COG1538	Outer membrane efflux protein
CSW01_RS08190	COG1748	Saccharopine dehydrogenase
CSW01_RS08205	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CSW01_RS08215	COG0577	efflux transmembrane transporter activity
CSW01_RS08220	COG4181	ATPase activity
CSW01_RS08225	COG0534	Mate efflux family protein
CSW01_RS08230	COG0702	epimerase
CSW01_RS08240	COG2814	Major facilitator Superfamily
CSW01_RS08245	COG1187	pseudouridine synthase activity
CSW01_RS08250	COG1061	Type III restriction enzyme res subunit
CSW01_RS08270	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CSW01_RS08275	COG5001	Diguanylate cyclase
CSW01_RS08275	COG4251	negative regulation of phosphorylation
CSW01_RS08275	COG2203	Gaf domain
CSW01_RS08275	COG3706	GGDEF domain
CSW01_RS08290	COG0840	transmembrane signaling receptor activity
CSW01_RS08320	COG4934	collagen metabolic process
CSW01_RS08335	COG2205	protein histidine kinase activity
CSW01_RS08335	COG0784	Response regulator, receiver
CSW01_RS08340	COG2239	Acts as a magnesium transporter
CSW01_RS08350	COG0814	amino acid
CSW01_RS08355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSW01_RS08360	COG1131	(ABC) transporter
CSW01_RS08365	COG0842	Transport permease protein
CSW01_RS08375	COG3313	Fe-S protein
CSW01_RS08385	COG4134	Bacterial extracellular solute-binding protein
CSW01_RS08390	COG4135	transport system, permease component
CSW01_RS08395	COG4136	ATPase activity
CSW01_RS08400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CSW01_RS08405	COG0564	pseudouridine synthase activity
CSW01_RS08410	COG0733	neurotransmitter:sodium symporter activity
CSW01_RS08425	COG0626	cystathionine gamma-synthase activity
CSW01_RS08430	COG2818	Glycosylase
CSW01_RS08445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSW01_RS08460	COG1842	Phage shock protein A
CSW01_RS08465	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CSW01_RS08475	COG4168	peptide transport system, permease
CSW01_RS08490	COG4172	Belongs to the ABC transporter superfamily
CSW01_RS08505	COG1227	inorganic diphosphatase activity
CSW01_RS08530	COG0243	molybdopterin cofactor binding
CSW01_RS08535	COG3005	denitrification pathway
CSW01_RS08540	COG4459	periplasmic nitrate reductase
CSW01_RS08550	COG2116	formate transmembrane transporter activity
CSW01_RS08565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSW01_RS08570	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CSW01_RS08585	COG1607	acyl-coa hydrolase
CSW01_RS08590	COG2350	Protein conserved in bacteria
CSW01_RS08600	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CSW01_RS08605	COG0583	DNA-binding transcription factor activity
CSW01_RS08620	COG0612	Peptidase, M16
CSW01_RS08625	COG5001	Diguanylate cyclase
CSW01_RS08630	COG1032	radical SAM domain protein
CSW01_RS08650	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CSW01_RS08660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CSW01_RS08665	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CSW01_RS08670	COG0745	RESPONSE REGULATOR receiver
CSW01_RS08675	COG3381	protein complex oligomerization
CSW01_RS08685	COG1609	Transcriptional regulator
CSW01_RS08690	COG3070	regulator of competence-specific genes
CSW01_RS08710	COG0297	glycogen (starch) synthase activity
CSW01_RS08715	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CSW01_RS08720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CSW01_RS08750	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CSW01_RS08760	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CSW01_RS08785	COG1012	belongs to the aldehyde dehydrogenase family
CSW01_RS08790	COG1309	transcriptional regulator
CSW01_RS08815	COG0668	transmembrane transport
CSW01_RS08820	COG2995	paraquat-inducible protein a
CSW01_RS08825	COG3008	intermembrane lipid transfer
CSW01_RS08825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CSW01_RS08835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSW01_RS08850	COG0582	viral genome integration into host DNA
CSW01_RS08855	COG0582	viral genome integration into host DNA
CSW01_RS08860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CSW01_RS08880	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CSW01_RS08900	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CSW01_RS08920	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CSW01_RS08925	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CSW01_RS08930	COG1737	Transcriptional regulator
CSW01_RS08935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSW01_RS08940	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSW01_RS08945	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CSW01_RS08950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSW01_RS08965	COG1940	carbohydrate kinase activity
CSW01_RS08970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CSW01_RS08975	COG4409	exo-alpha-(2->6)-sialidase activity
CSW01_RS08985	COG2003	Belongs to the UPF0758 family
CSW01_RS09000	COG3941	tape measure
CSW01_RS09045	COG0488	(ABC) transporter
CSW01_RS09125	COG0415	Belongs to the DNA photolyase family
CSW01_RS09135	COG4628	conserved protein (DUF2132)
CSW01_RS09140	COG3284	Transcriptional regulator
CSW01_RS09145	COG1012	belongs to the aldehyde dehydrogenase family
CSW01_RS09155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSW01_RS09160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSW01_RS09165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSW01_RS09175	COG2207	Transcriptional regulator
CSW01_RS09180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSW01_RS09180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSW01_RS09180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSW01_RS09185	COG1482	cell wall glycoprotein biosynthetic process
CSW01_RS09195	COG5002	protein histidine kinase activity
CSW01_RS09195	COG0784	Response regulator, receiver
CSW01_RS09205	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CSW01_RS09215	COG2885	chlorophyll binding
CSW01_RS09220	COG0823	Involved in the tonB-independent uptake of proteins
CSW01_RS09235	COG0811	peptide transport
CSW01_RS09240	COG0824	Thioesterase
CSW01_RS09245	COG3790	cyd operon protein YbgE
CSW01_RS09250	COG4890	Cyd operon protein YbgT
CSW01_RS09255	COG1294	oxidase, subunit
CSW01_RS09260	COG1271	oxidase subunit
CSW01_RS09270	COG0632	four-way junction helicase activity
CSW01_RS09275	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CSW01_RS09280	COG0215	cysteine-tRNA ligase activity
CSW01_RS09285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CSW01_RS09290	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSW01_RS09295	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CSW01_RS09300	COG3012	SEC-C Motif Domain Protein
CSW01_RS09305	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CSW01_RS09310	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CSW01_RS09315	COG1199	ATP-dependent helicase activity
CSW01_RS09320	COG0730	response to heat
CSW01_RS09325	COG3923	Primosomal replication protein n
CSW01_RS09335	COG0840	transmembrane signaling receptor activity
CSW01_RS09340	COG0708	Exodeoxyribonuclease III
CSW01_RS09345	COG4160	amino acid transport
CSW01_RS09375	COG1882	Formate acetyltransferase
CSW01_RS09385	COG0840	transmembrane signaling receptor activity
CSW01_RS09390	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CSW01_RS09400	COG3013	Belongs to the UPF0304 family
CSW01_RS09405	COG2766	serine protein kinase
CSW01_RS09410	COG2718	Belongs to the UPF0229 family
CSW01_RS09415	COG2719	SpoVR family
CSW01_RS09420	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CSW01_RS09425	COG2835	tetraacyldisaccharide 4'-kinase activity
CSW01_RS09430	COG1663	tetraacyldisaccharide 4'-kinase activity
CSW01_RS09435	COG1132	(ABC) transporter
CSW01_RS09440	COG0658	competence protein
CSW01_RS09440	COG2333	competence protein COMEC
CSW01_RS09450	COG4591	ABC-type transport system involved in lipoprotein release permease component
CSW01_RS09455	COG1136	(ABC) transporter
CSW01_RS09460	COG4591	ABC-type transport system involved in lipoprotein release permease component
CSW01_RS09470	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CSW01_RS09490	COG1252	NADH dehydrogenase
CSW01_RS09495	COG3150	esterase
CSW01_RS09520	COG0537	adenosine 5'-monophosphoramidase activity
CSW01_RS09535	COG2186	Transcriptional regulator
CSW01_RS09540	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CSW01_RS09545	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CSW01_RS09550	COG1674	ftsk spoiiie
CSW01_RS09560	COG0686	Belongs to the AlaDH PNT family
CSW01_RS09570	COG0583	DNA-binding transcription factor activity
CSW01_RS09590	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CSW01_RS09595	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CSW01_RS09600	COG0776	regulation of translation
CSW01_RS09605	COG0539	negative regulation of cytoplasmic translation
CSW01_RS09610	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CSW01_RS09615	COG1555	photosystem II stabilization
CSW01_RS09620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSW01_RS09625	COG0776	regulation of translation
CSW01_RS09630	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CSW01_RS09635	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CSW01_RS09645	COG0544	peptidyl-prolyl cis-trans isomerase activity
CSW01_RS09655	COG4191	Histidine kinase
CSW01_RS09665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CSW01_RS09670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CSW01_RS09675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CSW01_RS09680	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CSW01_RS09695	COG5001	Diguanylate cyclase
CSW01_RS09695	COG3300	MHYT domain
CSW01_RS09705	COG4589	Belongs to the CDS family
CSW01_RS09745	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CSW01_RS09755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSW01_RS09775	COG0243	molybdopterin cofactor binding
CSW01_RS09780	COG3005	denitrification pathway
CSW01_RS09785	COG3469	chitinase activity
CSW01_RS09785	COG3325	Belongs to the glycosyl hydrolase 18 family
CSW01_RS09790	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW01_RS09800	COG2951	lytic endotransglycosylase activity
CSW01_RS09805	COG3100	YcgL domain-containing protein
CSW01_RS09810	COG0850	regulation of cytokinetic process
CSW01_RS09815	COG2894	cell division
CSW01_RS09820	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CSW01_RS09825	COG3015	lipoprotein NlpE involved in copper resistance
CSW01_RS09845	COG0477	Major facilitator Superfamily
CSW01_RS09850	COG0840	transmembrane signaling receptor activity
CSW01_RS09855	COG1396	sequence-specific DNA binding
CSW01_RS09860	COG3135	benzoate transporter
CSW01_RS09880	COG0596	Alpha beta hydrolase
CSW01_RS09885	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CSW01_RS09890	COG1169	isochorismate synthase
CSW01_RS09895	COG0436	Aminotransferase
CSW01_RS09900	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CSW01_RS09905	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CSW01_RS09925	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CSW01_RS09930	COG0318	PFAM AMP-dependent synthetase and ligase
CSW01_RS09935	COG0596	Alpha beta hydrolase
CSW01_RS09950	COG1214	PFAM Peptidase M22, glycoprotease
CSW01_RS09955	COG1199	ATP-dependent helicase activity
CSW01_RS09970	COG0788	formyltetrahydrofolate deformylase activity
CSW01_RS09975	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSW01_RS09975	COG1902	pentaerythritol trinitrate reductase activity
CSW01_RS09980	COG0616	signal peptide processing
CSW01_RS09985	COG0252	asparaginase activity
CSW01_RS09990	COG3139	Protein of unknown function (DUF1315)
CSW01_RS10000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CSW01_RS10005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSW01_RS10010	COG0676	glucose-6-phosphate 1-epimerase activity
CSW01_RS10030	COG2226	methyltransferase
CSW01_RS10045	COG0784	Response regulator, receiver
CSW01_RS10045	COG0835	chemotaxis
CSW01_RS10050	COG1940	carbohydrate kinase activity
CSW01_RS10060	COG4667	esterase of the alpha-beta hydrolase superfamily
CSW01_RS10075	COG0733	neurotransmitter:sodium symporter activity
CSW01_RS10085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW01_RS10085	COG1263	PTS System
CSW01_RS10090	COG0084	hydrolase, TatD family'
CSW01_RS10100	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CSW01_RS10105	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CSW01_RS10110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSW01_RS10115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CSW01_RS10120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CSW01_RS10125	COG1028	Short-chain dehydrogenase reductase Sdr
CSW01_RS10135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CSW01_RS10140	COG0416	fatty acid biosynthetic process
CSW01_RS10145	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CSW01_RS10150	COG1399	metal-binding, possibly nucleic acid-binding protein
CSW01_RS10155	COG0424	maF-like protein
CSW01_RS10160	COG0564	pseudouridine synthase activity
CSW01_RS10175	COG1530	ribonuclease E activity
CSW01_RS10180	COG0659	secondary active sulfate transmembrane transporter activity
CSW01_RS10195	COG1454	alcohol dehydrogenase
CSW01_RS10195	COG1012	belongs to the aldehyde dehydrogenase family
CSW01_RS10200	COG2095	MarC family integral membrane protein
CSW01_RS10205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSW01_RS10210	COG1757	Na H antiporter
CSW01_RS10220	COG3081	Nucleoid-associated protein
CSW01_RS10225	COG3082	Protein of unknown function (DUF1414)
CSW01_RS10230	COG3083	sulfuric ester hydrolase activity
CSW01_RS10245	COG0123	including yeast histone deacetylase and acetoin utilization protein
CSW01_RS10250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CSW01_RS10255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CSW01_RS10275	COG2853	Lipoprotein
CSW01_RS10285	COG3088	subunit of a heme lyase
CSW01_RS10285	COG4235	cytochrome complex assembly
CSW01_RS10290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSW01_RS10295	COG1138	Cytochrome C-type biogenesis protein
CSW01_RS10300	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CSW01_RS10310	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSW01_RS10315	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSW01_RS10320	COG4133	protoheme IX ABC transporter activity
CSW01_RS10330	COG0835	chemotaxis
CSW01_RS10340	COG1192	Involved in chromosome partitioning
CSW01_RS10345	COG2201	protein-glutamate methylesterase activity
CSW01_RS10350	COG0784	Response regulator, receiver
CSW01_RS10350	COG2198	Histidine kinase
CSW01_RS10350	COG0643	Histidine kinase
CSW01_RS10355	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CSW01_RS10385	COG2062	phosphohistidine phosphatase, SixA
CSW01_RS10390	COG1025	Belongs to the peptidase M16 family
CSW01_RS10400	COG0018	arginyl-trna synthetase
CSW01_RS10420	COG1918	ferrous iron import across plasma membrane
CSW01_RS10425	COG4977	sequence-specific DNA binding
CSW01_RS10430	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CSW01_RS10435	COG1121	(ABC) transporter
CSW01_RS10440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSW01_RS10450	COG0045	succinate-CoA ligase (ADP-forming) activity
CSW01_RS10455	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSW01_RS10460	COG0567	Dehydrogenase, E1 component
CSW01_RS10470	COG1053	succinate dehydrogenase
CSW01_RS10475	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CSW01_RS10480	COG2009	succinate dehydrogenase
CSW01_RS10485	COG0372	Belongs to the citrate synthase family
CSW01_RS10490	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CSW01_RS10500	COG0033	Phosphoglucomutase
CSW01_RS10505	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CSW01_RS10510	COG0596	Alpha beta hydrolase
CSW01_RS10525	COG1346	cytolysis
CSW01_RS10535	COG0583	DNA-binding transcription factor activity
CSW01_RS10545	COG0735	belongs to the Fur family
CSW01_RS10550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSW01_RS10555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSW01_RS10560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CSW01_RS10570	COG0431	NADPH-dependent FMN reductase
CSW01_RS10580	COG3101	peptidyl-lysine hydroxylation
CSW01_RS10585	COG2860	membrane
CSW01_RS10590	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CSW01_RS10600	COG2890	protein-(glutamine-N5) methyltransferase activity
CSW01_RS10605	COG2840	Smr protein MutS2
CSW01_RS10615	COG1684	flagellar biosynthetic protein fliR
CSW01_RS10620	COG1987	bacterial-type flagellum assembly
CSW01_RS10645	COG1580	Controls the rotational direction of flagella during chemotaxis
CSW01_RS10670	COG1317	bacterial-type flagellum organization
CSW01_RS10675	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSW01_RS10685	COG1677	Flagellar hook-basal body complex protein FliE
CSW01_RS10705	COG1516	flagellar protein fliS
CSW01_RS10715	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CSW01_RS10720	COG1334	flagellar protein FlaG
CSW01_RS10725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW01_RS10730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW01_RS10735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW01_RS10740	COG2837	iron assimilation
CSW01_RS10760	COG1393	Belongs to the ArsC family
CSW01_RS10770	COG1876	peptidase activity
CSW01_RS10780	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CSW01_RS10795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CSW01_RS10800	COG0840	transmembrane signaling receptor activity
CSW01_RS10815	COG4783	chaperone-mediated protein folding
CSW01_RS10820	COG1393	Belongs to the ArsC family
CSW01_RS10840	COG2233	PERMEase
CSW01_RS10845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CSW01_RS10850	COG0737	Belongs to the 5'-nucleotidase family
CSW01_RS10855	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CSW01_RS10860	COG2912	Transglutaminase-like superfamily
CSW01_RS10870	COG2890	protein-(glutamine-N5) methyltransferase activity
CSW01_RS10875	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CSW01_RS10880	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CSW01_RS10885	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CSW01_RS10895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CSW01_RS10900	COG0193	aminoacyl-tRNA hydrolase activity
CSW01_RS10905	COG0012	GTP binding
CSW01_RS10970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW01_RS11100	COG4695	Portal protein
CSW01_RS11195	COG4974	Belongs to the 'phage' integrase family
CSW01_RS11200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW01_RS11215	COG3951	Flagellar rod assembly protein muramidase FlgJ
CSW01_RS11215	COG1705	Flagellar rod assembly protein muramidase FlgJ
CSW01_RS11220	COG1706	bacterial-type flagellum-dependent cell motility
CSW01_RS11225	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CSW01_RS11235	COG4787	bacterial-type flagellum-dependent cell motility
CSW01_RS11240	COG1749	Flagellar hook protein flgE
CSW01_RS11255	COG1815	bacterial-type flagellum-dependent cell motility
CSW01_RS11260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CSW01_RS11265	COG0835	chemotaxis
CSW01_RS11265	COG0784	Response regulator, receiver
CSW01_RS11300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSW01_RS11300	COG3433	isochorismatase activity
CSW01_RS11300	COG2226	methyltransferase
CSW01_RS11305	COG2375	cellular response to nickel ion
CSW01_RS11310	COG4774	siderophore transport
CSW01_RS11310	COG1629	transport
CSW01_RS11325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CSW01_RS11330	COG2217	Heavy metal translocating P-type atpase
CSW01_RS11330	COG2608	mercury ion transmembrane transporter activity
CSW01_RS11345	COG3735	TraB family
CSW01_RS11360	COG2840	Smr protein MutS2
CSW01_RS11365	COG1187	pseudouridine synthase activity
CSW01_RS11375	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CSW01_RS11380	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CSW01_RS11385	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CSW01_RS11390	COG0121	glutamine amidotransferase
CSW01_RS11395	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CSW01_RS11400	COG1960	acyl-CoA dehydrogenase activity
CSW01_RS11415	COG0328	RNA-DNA hybrid ribonuclease activity
CSW01_RS11420	COG2226	methyltransferase
CSW01_RS11425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW01_RS11430	COG0741	lytic transglycosylase activity
CSW01_RS11430	COG1388	LysM domain
CSW01_RS11435	COG3021	interspecies interaction between organisms
CSW01_RS11440	COG0347	Belongs to the P(II) protein family
CSW01_RS11445	COG3479	Phenolic acid decarboxylase
CSW01_RS11455	COG0037	tRNA processing
CSW01_RS11460	COG0825	malonyl-CoA metabolic process
CSW01_RS11465	COG0587	DNA-directed DNA polymerase activity
CSW01_RS11470	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CSW01_RS11475	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSW01_RS11480	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSW01_RS11485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CSW01_RS11490	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSW01_RS11495	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CSW01_RS11505	COG0750	zinc metalloprotease
CSW01_RS11510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CSW01_RS11515	COG0575	Belongs to the CDS family
CSW01_RS11520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CSW01_RS11525	COG0233	cytoplasmic translational termination
CSW01_RS11530	COG0528	UMP kinase activity
CSW01_RS11535	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CSW01_RS11540	COG0052	Belongs to the universal ribosomal protein uS2 family
CSW01_RS11545	COG0024	Methionine aminopeptidase
CSW01_RS11550	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CSW01_RS11565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CSW01_RS11570	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CSW01_RS11575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CSW01_RS11580	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CSW01_RS11595	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSW01_RS11595	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSW01_RS11600	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CSW01_RS11605	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CSW01_RS11610	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CSW01_RS11620	COG1073	alpha beta
CSW01_RS11625	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CSW01_RS11630	COG2252	PERMEase
CSW01_RS11635	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSW01_RS11640	COG0189	ligase activity
CSW01_RS11640	COG4067	protein conserved in archaea
CSW01_RS11645	COG0189	ligase activity
CSW01_RS11655	COG0733	neurotransmitter:sodium symporter activity
CSW01_RS11660	COG3706	GGDEF domain
CSW01_RS11680	COG1477	protein flavinylation
CSW01_RS11685	COG2871	sodium ion transport
CSW01_RS11690	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CSW01_RS11695	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CSW01_RS11700	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CSW01_RS11705	COG1805	sodium ion transport
CSW01_RS11710	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CSW01_RS11715	COG0271	Belongs to the BolA IbaG family
CSW01_RS11720	COG2813	Specifically methylates the guanine in position
CSW01_RS11730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CSW01_RS11740	COG2211	Major facilitator Superfamily
CSW01_RS11750	COG1595	DNA-templated transcription, initiation
CSW01_RS11760	COG3248	Nucleoside-binding outer membrane protein
CSW01_RS11765	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CSW01_RS11770	COG0693	protein deglycase activity
CSW01_RS11775	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CSW01_RS11780	COG2166	iron-sulfur cluster assembly
CSW01_RS11785	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CSW01_RS11790	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CSW01_RS11800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CSW01_RS11800	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CSW01_RS11810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSW01_RS11815	COG1074	ATP-dependent DNA helicase activity
CSW01_RS11820	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CSW01_RS11835	COG3141	response to X-ray
CSW01_RS11840	COG2171	N-acyltransferase activity
CSW01_RS11850	COG0456	acetyltransferase
CSW01_RS11855	COG0569	domain protein
CSW01_RS11855	COG0189	ligase activity
CSW01_RS11870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSW01_RS11875	COG1609	Transcriptional regulator
CSW01_RS11880	COG3250	beta-galactosidase activity
CSW01_RS11895	COG1022	Amp-dependent synthetase and ligase
CSW01_RS11900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CSW01_RS11905	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CSW01_RS11920	COG0560	Phosphoserine phosphatase
CSW01_RS11930	COG0813	purine-nucleoside phosphorylase activity
CSW01_RS11935	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CSW01_RS11940	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CSW01_RS11945	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CSW01_RS11955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW01_RS11960	COG0084	hydrolase, TatD family'
CSW01_RS11965	COG3022	response to hydroperoxide
CSW01_RS11970	COG1115	amino acid carrier protein
CSW01_RS11985	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CSW01_RS11990	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CSW01_RS11995	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CSW01_RS12000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CSW01_RS12025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CSW01_RS12035	COG0745	RESPONSE REGULATOR receiver
CSW01_RS12040	COG5002	protein histidine kinase activity
CSW01_RS12040	COG0784	Response regulator, receiver
CSW01_RS12040	COG2198	Histidine kinase
CSW01_RS12045	COG2203	Gaf domain
CSW01_RS12045	COG5001	Diguanylate cyclase
CSW01_RS12045	COG4251	negative regulation of phosphorylation
CSW01_RS12045	COG3706	GGDEF domain
CSW01_RS12050	COG1242	4 iron, 4 sulfur cluster binding
CSW01_RS12055	COG0069	glutamate synthase activity
CSW01_RS12055	COG0070	glutamate synthase
CSW01_RS12055	COG0067	glutamate synthase
CSW01_RS12065	COG0067	glutamate synthase
CSW01_RS12065	COG0070	glutamate synthase
CSW01_RS12065	COG0069	glutamate synthase activity
CSW01_RS12070	COG0493	'glutamate synthase
CSW01_RS12080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CSW01_RS12090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW01_RS12095	COG2860	membrane
CSW01_RS12100	COG0583	DNA-binding transcription factor activity
CSW01_RS12105	COG0730	response to heat
CSW01_RS12115	COG4172	Belongs to the ABC transporter superfamily
CSW01_RS12135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CSW01_RS12140	COG0505	Belongs to the CarA family
CSW01_RS12150	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CSW01_RS12155	COG0494	nUDIX hydrolase
CSW01_RS12160	COG0653	protein targeting
CSW01_RS12170	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CSW01_RS12175	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CSW01_RS12180	COG0849	cell division
CSW01_RS12185	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CSW01_RS12190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CSW01_RS12200	COG0772	Belongs to the SEDS family
CSW01_RS12205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CSW01_RS12215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CSW01_RS12220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CSW01_RS12225	COG0768	penicillin binding
CSW01_RS12230	COG3116	cell division
CSW01_RS12245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSW01_RS12250	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSW01_RS12255	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CSW01_RS12260	COG2186	Transcriptional regulator
CSW01_RS12270	COG0737	Belongs to the 5'-nucleotidase family
CSW01_RS12275	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CSW01_RS12280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CSW01_RS12285	COG4974	Belongs to the 'phage' integrase family
CSW01_RS12290	COG0716	FMN binding
CSW01_RS12310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CSW01_RS12315	COG1459	type II secretion system
CSW01_RS12325	COG0237	dephospho-CoA kinase activity
CSW01_RS12330	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CSW01_RS12340	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CSW01_RS12345	COG0187	DNA topoisomerase II activity
CSW01_RS12350	COG3150	esterase
CSW01_RS12360	COG3151	Protein conserved in bacteria
CSW01_RS12365	COG0494	nUDIX hydrolase
CSW01_RS12370	COG1538	Outer membrane efflux protein
CSW01_RS12380	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CSW01_RS12385	COG0840	transmembrane signaling receptor activity
CSW01_RS12390	COG3025	triphosphatase activity
CSW01_RS12395	COG1392	Phosphate transport regulator
CSW01_RS12400	COG0306	phosphate transporter
CSW01_RS12405	COG4991	sh3 domain protein
CSW01_RS12415	COG3409	Peptidoglycan-binding domain 1 protein
CSW01_RS12415	COG3267	Type II secretory pathway component ExeA
CSW01_RS12425	COG0148	phosphopyruvate hydratase activity
CSW01_RS12430	COG0504	CTP synthase activity
CSW01_RS12435	COG3956	TIGRFAM MazG family protein
CSW01_RS12440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CSW01_RS12455	COG5001	Diguanylate cyclase
CSW01_RS12475	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CSW01_RS12480	COG1381	Involved in DNA repair and RecF pathway recombination
CSW01_RS12485	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CSW01_RS12500	COG0481	GTPase activity
CSW01_RS12505	COG3086	response to oxidative stress
CSW01_RS12520	COG1595	DNA-templated transcription, initiation
CSW01_RS12530	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CSW01_RS12540	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CSW01_RS12555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSW01_RS12560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSW01_RS12565	COG3079	Belongs to the UPF0149 family
CSW01_RS12570	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CSW01_RS12580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CSW01_RS12585	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CSW01_RS12590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSW01_RS12600	COG0440	acetolactate synthase activity
CSW01_RS12605	COG0028	Belongs to the TPP enzyme family
CSW01_RS12610	COG1022	Amp-dependent synthetase and ligase
CSW01_RS12615	COG0583	DNA-binding transcription factor activity
CSW01_RS12640	COG0473	3-isopropylmalate dehydrogenase activity
CSW01_RS12645	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CSW01_RS12650	COG0066	3-isopropylmalate dehydratase activity
CSW01_RS12695	COG3437	response regulator, receiver
CSW01_RS12710	COG0795	lipopolysaccharide-transporting ATPase activity
CSW01_RS12715	COG0795	lipopolysaccharide-transporting ATPase activity
CSW01_RS12720	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CSW01_RS12725	COG2927	DNA polymerase III (CHI subunit)
CSW01_RS12730	COG0525	valine-tRNA ligase activity
CSW01_RS12735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CSW01_RS12740	COG0564	pseudouridine synthase activity
CSW01_RS12755	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CSW01_RS12765	COG0540	Belongs to the ATCase OTCase family
CSW01_RS12775	COG0251	oxidation-reduction process
CSW01_RS12785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CSW01_RS12790	COG5007	Belongs to the BolA IbaG family
CSW01_RS12800	COG2854	intermembrane phospholipid transfer
CSW01_RS12805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CSW01_RS12810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CSW01_RS12815	COG1127	ABC transporter
CSW01_RS12830	COG0517	IMP dehydrogenase activity
CSW01_RS12830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CSW01_RS12845	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CSW01_RS12850	COG1137	ATPase activity
CSW01_RS12860	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CSW01_RS12865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSW01_RS12870	COG1660	Displays ATPase and GTPase activities
CSW01_RS12875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSW01_RS12880	COG2239	Acts as a magnesium transporter
CSW01_RS12885	COG0312	modulator of DNA gyrase
CSW01_RS12890	COG3028	Belongs to the UPF0307 family
CSW01_RS12895	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CSW01_RS12900	COG1178	ABC-type Fe3 transport system permease component
CSW01_RS12910	COG0163	prenyltransferase activity
CSW01_RS12915	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CSW01_RS12930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CSW01_RS12935	COG2105	PFAM AIG2 family protein
CSW01_RS12945	COG0729	surface antigen
CSW01_RS12950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CSW01_RS12955	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CSW01_RS12970	COG1136	(ABC) transporter
CSW01_RS12990	COG0529	Catalyzes the synthesis of activated sulfate
CSW01_RS13005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CSW01_RS13005	COG1648	precorrin-2 dehydrogenase activity
CSW01_RS13010	COG0737	Belongs to the 5'-nucleotidase family
CSW01_RS13020	COG0513	Belongs to the DEAD box helicase family
CSW01_RS13025	COG2153	protein acetylation
CSW01_RS13030	COG0697	spore germination
CSW01_RS13035	COG3061	Opacity-associated protein A
CSW01_RS13035	COG3266	domain, Protein
CSW01_RS13040	COG0545	Peptidyl-prolyl cis-trans isomerase
CSW01_RS13050	COG0203	ribosomal protein L17
CSW01_RS13055	COG0202	RNA polymerase activity
CSW01_RS13060	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CSW01_RS13065	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CSW01_RS13070	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CSW01_RS13075	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CSW01_RS13080	COG0201	protein transport
CSW01_RS13090	COG1841	ribosomal large subunit assembly
CSW01_RS13095	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CSW01_RS13100	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CSW01_RS13110	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CSW01_RS13115	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CSW01_RS13120	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CSW01_RS13125	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CSW01_RS13130	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CSW01_RS13135	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CSW01_RS13140	COG0255	Belongs to the universal ribosomal protein uL29 family
CSW01_RS13145	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CSW01_RS13150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CSW01_RS13155	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CSW01_RS13160	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CSW01_RS13165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CSW01_RS13170	COG0089	rRNA binding
CSW01_RS13175	COG0088	Forms part of the polypeptide exit tunnel
CSW01_RS13180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CSW01_RS13185	COG0051	transcription antitermination factor activity, RNA binding
CSW01_RS13190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSW01_RS13195	COG0557	exoribonuclease II activity
CSW01_RS13200	COG3083	sulfuric ester hydrolase activity
CSW01_RS13205	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CSW01_RS13225	COG1047	Peptidyl-prolyl cis-trans
CSW01_RS13240	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSW01_RS13245	COG0488	(ABC) transporter
CSW01_RS13255	COG0429	hydrolase of the alpha beta-hydrolase fold
CSW01_RS13265	COG3954	Phosphoribulokinase
CSW01_RS13280	COG1012	belongs to the aldehyde dehydrogenase family
CSW01_RS13290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CSW01_RS13300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CSW01_RS13315	COG0180	Tryptophanyl-tRNA synthetase
CSW01_RS13320	COG0546	phosphoglycolate phosphatase activity
CSW01_RS13325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CSW01_RS13330	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CSW01_RS13340	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CSW01_RS13345	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CSW01_RS13375	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CSW01_RS13385	COG0678	peroxiredoxin activity
CSW01_RS13385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CSW01_RS13390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSW01_RS13400	COG0165	Argininosuccinate lyase
CSW01_RS13410	COG0137	argininosuccinate synthase activity
CSW01_RS13415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CSW01_RS13420	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CSW01_RS13425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CSW01_RS13430	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CSW01_RS13440	COG1045	serine acetyltransferase
CSW01_RS13445	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CSW01_RS13450	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CSW01_RS13455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW01_RS13460	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CSW01_RS13465	COG1053	succinate dehydrogenase
CSW01_RS13470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSW01_RS13475	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CSW01_RS13485	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CSW01_RS13490	COG1509	lysine 2,3-aminomutase activity
CSW01_RS13500	COG0459	protein refolding
CSW01_RS13505	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CSW01_RS13535	COG0149	triose-phosphate isomerase activity
CSW01_RS13540	COG0534	Mate efflux family protein
CSW01_RS13545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CSW01_RS13550	COG1575	Belongs to the MenA family. Type 1 subfamily
CSW01_RS13555	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CSW01_RS13560	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CSW01_RS13565	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CSW01_RS13570	COG1609	Transcriptional regulator
CSW01_RS13575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CSW01_RS13580	COG0254	rRNA binding
CSW01_RS13585	COG0281	malic enzyme
CSW01_RS13590	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
CSW01_RS13595	COG0626	cystathionine gamma-synthase activity
CSW01_RS13600	COG0527	aspartate kinase activity
CSW01_RS13600	COG0460	homoserine dehydrogenase
CSW01_RS13605	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CSW01_RS13610	COG3074	FtsZ-dependent cytokinesis
CSW01_RS13615	COG1494	fructose-1,6-bisphosphatase
CSW01_RS13620	COG0205	6-phosphofructokinase activity
CSW01_RS13625	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CSW01_RS13635	COG0745	RESPONSE REGULATOR receiver
CSW01_RS13640	COG2205	protein histidine kinase activity
CSW01_RS13650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CSW01_RS13655	COG3030	protein affecting phage T7 exclusion by the F plasmid
CSW01_RS13660	COG3706	GGDEF domain
CSW01_RS13665	COG1027	Aspartate ammonia-lyase
CSW01_RS13670	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CSW01_RS13680	COG4232	protein-disulfide reductase activity
CSW01_RS13700	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSW01_RS13705	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CSW01_RS13710	COG0194	GDP metabolic process
CSW01_RS13715	COG1758	RNA polymerase activity
CSW01_RS13720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CSW01_RS13725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CSW01_RS13730	COG2233	PERMEase
CSW01_RS13745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CSW01_RS13750	COG2183	response to ionizing radiation
CSW01_RS13760	COG0596	Alpha beta hydrolase
CSW01_RS13765	COG1040	competence protein
CSW01_RS13775	COG0494	nUDIX hydrolase
CSW01_RS13780	COG1218	3'(2'),5'-bisphosphate nucleotidase
CSW01_RS13790	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CSW01_RS13795	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CSW01_RS13800	COG3156	type II secretion system protein K
CSW01_RS13805	COG4795	General secretion pathway protein
CSW01_RS13810	COG2165	general secretion pathway protein
CSW01_RS13815	COG2165	general secretion pathway protein
CSW01_RS13820	COG2165	general secretion pathway protein
CSW01_RS13825	COG1459	type II secretion system
CSW01_RS13830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CSW01_RS13840	COG3031	protein transport across the cell outer membrane
CSW01_RS13845	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CSW01_RS13850	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CSW01_RS13855	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CSW01_RS13865	COG0456	acetyltransferase
CSW01_RS13870	COG1490	D-aminoacyl-tRNA deacylase activity
CSW01_RS13875	COG1295	ribonuclease BN
CSW01_RS13880	COG1660	Displays ATPase and GTPase activities
CSW01_RS13885	COG1217	gtp-binding protein TYPA
CSW01_RS13895	COG0174	glutamine synthetase
CSW01_RS13905	COG3852	Histidine kinase
CSW01_RS13915	COG5001	Diguanylate cyclase
CSW01_RS13915	COG3300	MHYT domain
CSW01_RS13920	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CSW01_RS14000	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CSW01_RS14005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSW01_RS14010	COG1739	Uncharacterized protein family UPF0029
CSW01_RS14020	COG0183	Belongs to the thiolase family
CSW01_RS14025	COG0583	DNA-binding transcription factor activity
CSW01_RS14030	COG2814	Major facilitator Superfamily
CSW01_RS14035	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CSW01_RS14040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CSW01_RS14045	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CSW01_RS14050	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CSW01_RS14055	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CSW01_RS14060	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CSW01_RS14065	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CSW01_RS14075	COG0356	it plays a direct role in the translocation of protons across the membrane
CSW01_RS14080	COG3312	ion transport
CSW01_RS14085	COG1475	DNA binding
CSW01_RS14090	COG1192	Involved in chromosome partitioning
CSW01_RS14100	COG0445	tRNA wobble uridine modification
CSW01_RS14130	COG0217	transcriptional regulatory protein
CSW01_RS14135	COG2084	Dehydrogenase
CSW01_RS14155	COG2909	trisaccharide binding
CSW01_RS14160	COG0058	SHG alpha-glucan phosphorylase activity
CSW01_RS14165	COG1640	4-alpha-glucanotransferase
CSW01_RS14170	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CSW01_RS14185	COG3501	Rhs element vgr protein
CSW01_RS14190	COG4104	PAAR repeat-containing protein
CSW01_RS14220	COG0471	metal ion transport
CSW01_RS14225	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CSW01_RS14270	COG0671	phosphoesterase, PA-phosphatase related
CSW01_RS14275	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CSW01_RS14285	COG1999	signal sequence binding
CSW01_RS14300	COG0786	glutamate:sodium symporter activity
CSW01_RS14320	COG1566	PFAM secretion protein HlyD family protein
CSW01_RS14345	COG0813	purine-nucleoside phosphorylase activity
CSW01_RS14355	COG3272	Protein of unknown function (DUF1722)
CSW01_RS14365	COG0415	Belongs to the DNA photolyase family
CSW01_RS14370	COG1388	LysM domain
CSW01_RS14370	COG1376	ErfK ybiS ycfS ynhG family protein
CSW01_RS14380	COG0513	Belongs to the DEAD box helicase family
CSW01_RS14385	COG1770	oligopeptidase
CSW01_RS14415	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CSW01_RS14420	COG0573	inorganic phosphate transmembrane transporter activity
CSW01_RS14425	COG0581	inorganic phosphate transmembrane transporter activity
CSW01_RS14430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CSW01_RS14450	COG3314	Sporulation integral membrane protein YlbJ
CSW01_RS14455	COG0659	secondary active sulfate transmembrane transporter activity
CSW01_RS14465	COG0739	heme binding
CSW01_RS14470	COG3300	MHYT domain
CSW01_RS14470	COG5001	Diguanylate cyclase
CSW01_RS14475	COG0583	DNA-binding transcription factor activity
CSW01_RS14480	COG2814	Major facilitator Superfamily
CSW01_RS14505	COG1301	dicarboxylic acid transport
CSW01_RS14515	COG1342	Belongs to the UPF0251 family
CSW01_RS14550	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CSW01_RS14555	COG0673	inositol 2-dehydrogenase activity
CSW01_RS14565	COG2200	EAL domain
CSW01_RS14565	COG2771	luxR family
CSW01_RS14570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSW01_RS14580	COG0564	pseudouridine synthase activity
CSW01_RS14645	COG3829	transcription factor binding
CSW01_RS14675	COG3409	Peptidoglycan-binding domain 1 protein
CSW01_RS14675	COG3501	Rhs element vgr protein
CSW01_RS14690	COG1869	D-ribose catabolic process
CSW01_RS14695	COG1129	ABC transporter
CSW01_RS14700	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSW01_RS14705	COG1879	ABC-type sugar transport system periplasmic component
CSW01_RS14710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSW01_RS14715	COG1609	Transcriptional regulator
CSW01_RS14725	COG3201	nicotinamide mononucleotide transporter
CSW01_RS14730	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CSW01_RS14740	COG0584	glycerophosphoryl diester phosphodiesterase
CSW01_RS14745	COG2271	Major facilitator Superfamily
CSW01_RS14785	COG0579	oxidoreductase
CSW01_RS14795	COG0242	peptide deformylase activity
CSW01_RS14805	COG1320	monovalent cation:proton antiporter activity
CSW01_RS14810	COG2212	antiporter activity
CSW01_RS14815	COG1863	multisubunit Na H antiporter MnhE subunit
CSW01_RS14820	COG0651	ATP synthesis coupled electron transport
CSW01_RS14825	COG1006	Multisubunit Na H antiporter MnhC subunit
CSW01_RS14830	COG2111	Na H antiporter
CSW01_RS14830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSW01_RS14840	COG0589	response to stress
CSW01_RS14845	COG0814	amino acid
CSW01_RS14860	COG3530	Putative quorum-sensing-regulated virulence factor
CSW01_RS14870	COG5002	protein histidine kinase activity
CSW01_RS14870	COG5001	Diguanylate cyclase
CSW01_RS14875	COG1278	Cold shock
CSW01_RS14890	COG2304	oxidoreductase activity
CSW01_RS14910	COG0714	Associated with various cellular activities
CSW01_RS14915	COG0840	transmembrane signaling receptor activity
CSW01_RS14930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW01_RS14935	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSW01_RS14945	COG3604	Transcriptional regulator
CSW01_RS14950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSW01_RS14950	COG1017	nitric oxide dioxygenase activity
CSW01_RS14955	COG1278	Cold shock
CSW01_RS14960	COG3036	rescue of stalled ribosome
CSW01_RS14985	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CSW01_RS14985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CSW01_RS14990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CSW01_RS15000	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSW01_RS15015	COG0516	GMP reductase activity
CSW01_RS15055	COG0513	Belongs to the DEAD box helicase family
CSW01_RS15060	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CSW01_RS15065	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CSW01_RS15070	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CSW01_RS15080	COG3437	response regulator, receiver
CSW01_RS15080	COG0784	Response regulator, receiver
CSW01_RS15085	COG4191	Histidine kinase
CSW01_RS15085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW01_RS15095	COG1757	Na H antiporter
CSW01_RS15100	COG2814	Major facilitator Superfamily
CSW01_RS15110	COG3706	GGDEF domain
CSW01_RS15115	COG3240	lipase activity
CSW01_RS15125	COG0840	transmembrane signaling receptor activity
CSW01_RS15130	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CSW01_RS15135	COG5380	lipid catabolic process
CSW01_RS15160	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW01_RS15165	COG4605	iron ion homeostasis
CSW01_RS15170	COG4604	ABC transporter, ATP-binding protein
CSW01_RS15175	COG2207	Transcriptional regulator
CSW01_RS15190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CSW01_RS15210	COG0745	RESPONSE REGULATOR receiver
CSW01_RS15220	COG3623	hexulose-6-phosphate isomerase
CSW01_RS15225	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CSW01_RS15230	COG0561	phosphatase activity
CSW01_RS15260	COG3038	cytochrome b561
CSW01_RS15265	COG0366	Alpha amylase catalytic
CSW01_RS15285	COG0745	RESPONSE REGULATOR receiver
CSW01_RS15290	COG5002	protein histidine kinase activity
CSW01_RS15315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CSW01_RS15330	COG2814	Major facilitator Superfamily
CSW01_RS15345	COG1686	Belongs to the peptidase S11 family
CSW01_RS15375	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CSW01_RS15375	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CSW01_RS15380	COG0509	glycine decarboxylation via glycine cleavage system
CSW01_RS15385	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CSW01_RS15395	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CSW01_RS15405	COG3039	Transposase
CSW01_RS15440	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CSW01_RS15445	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CSW01_RS15510	COG1028	Short-chain dehydrogenase reductase Sdr
CSW01_RS15565	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CSW01_RS15595	COG0494	nUDIX hydrolase
CSW01_RS15620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW01_RS15625	COG3040	lipid binding
CSW01_RS15670	COG3041	Addiction module toxin RelE StbE family
CSW01_RS15785	COG1619	proteins homologs of microcin C7 resistance protein MccF
CSW01_RS15855	COG0346	lactoylglutathione lyase activity
CSW01_RS15870	COG3040	lipid binding
CSW01_RS15890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CSW01_RS15900	COG1280	lysine exporter protein (LysE YggA)
CSW01_RS16125	COG3549	Plasmid maintenance system killer
CSW01_RS16130	COG3093	addiction module antidote protein HigA
CSW01_RS16160	COG0384	phenazine biosynthesis protein PhzF
CSW01_RS16200	COG0346	lactoylglutathione lyase activity
CSW01_RS16240	COG3040	lipid binding
CSW01_RS16310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW01_RS16340	COG0384	phenazine biosynthesis protein PhzF
CSW01_RS16450	COG1619	proteins homologs of microcin C7 resistance protein MccF
CSW01_RS16475	COG3040	lipid binding
CSW01_RS16550	COG4977	sequence-specific DNA binding
CSW01_RS16660	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CSW01_RS16665	COG2944	sequence-specific DNA binding
CSW01_RS16680	COG3039	Transposase
CSW01_RS16685	COG0110	maltose O-acetyltransferase activity
CSW01_RS16705	COG0346	lactoylglutathione lyase activity
CSW01_RS16880	COG0346	lactoylglutathione lyase activity
CSW01_RS16900	COG1328	CTP reductase activity
CSW01_RS16905	COG0602	queuosine metabolic process
CSW01_RS16915	COG4067	protein conserved in archaea
CSW01_RS16915	COG0189	ligase activity
CSW01_RS16920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSW01_RS16920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSW01_RS16920	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CSW01_RS16925	COG1105	Belongs to the carbohydrate kinase PfkB family
CSW01_RS16930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSW01_RS16930	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSW01_RS16935	COG1609	Transcriptional regulator
CSW01_RS16940	COG0420	3'-5' exonuclease activity
CSW01_RS16945	COG0419	ATPase involved in DNA repair
CSW01_RS16950	COG0784	Response regulator, receiver
CSW01_RS16950	COG2205	protein histidine kinase activity
CSW01_RS16960	COG0156	8-amino-7-oxononanoate synthase activity
CSW01_RS16975	COG0523	cobalamin synthesis protein
CSW01_RS16990	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSW01_RS16990	COG0674	pyruvate-flavodoxin oxidoreductase activity
CSW01_RS16990	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CSW01_RS16990	COG1013	pyruvate-flavodoxin oxidoreductase activity
CSW01_RS16995	COG2205	protein histidine kinase activity
CSW01_RS17000	COG0745	RESPONSE REGULATOR receiver
CSW01_RS17005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CSW01_RS17010	COG0586	Pfam SNARE associated Golgi protein
CSW01_RS17020	COG2200	EAL domain
CSW01_RS17030	COG3038	cytochrome b561
CSW01_RS17040	COG2116	formate transmembrane transporter activity
CSW01_RS17045	COG0583	DNA-binding transcription factor activity
CSW01_RS17055	COG3593	DNA synthesis involved in DNA repair
CSW01_RS17060	COG0737	Belongs to the 5'-nucleotidase family
CSW01_RS17075	COG2824	Alkylphosphonate utilization operon protein PhnA
CSW01_RS17110	COG2199	diguanylate cyclase activity
CSW01_RS17130	COG3706	GGDEF domain
CSW01_RS17145	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CSW01_RS17150	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CSW01_RS17160	COG0745	RESPONSE REGULATOR receiver
CSW01_RS17175	COG3140	Belongs to the UPF0181 family
CSW01_RS17180	COG0023	Translation Initiation Factor
CSW01_RS17200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW01_RS17200	COG1042	CoA-binding domain protein
CSW01_RS17200	COG0045	succinate-CoA ligase (ADP-forming) activity
CSW01_RS17205	COG0583	DNA-binding transcription factor activity
CSW01_RS17210	COG4771	TonB-dependent receptor
CSW01_RS17210	COG1629	transport
CSW01_RS17225	COG2050	protein possibly involved in aromatic compounds catabolism
CSW01_RS17250	COG0625	glutathione transferase activity
CSW01_RS17265	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CSW01_RS17270	COG4172	Belongs to the ABC transporter superfamily
CSW01_RS17275	COG4239	(ABC) transporter, permease
CSW01_RS17280	COG4174	ABC transporter (Permease)
CSW01_RS17285	COG4166	transmembrane transport
CSW01_RS17310	COG3104	oligopeptide transport
CSW01_RS17330	COG3842	ATPase activity
CSW01_RS17340	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CSW01_RS17345	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSW01_RS17350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSW01_RS17355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CSW01_RS17360	COG1011	Hydrolase
CSW01_RS17370	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CSW01_RS17375	COG1970	mechanosensitive ion channel activity
CSW01_RS17380	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CSW01_RS17385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CSW01_RS17385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CSW01_RS17390	COG0302	gtp cyclohydrolase
CSW01_RS17400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSW01_RS17410	COG2897	thiosulfate sulfurtransferase activity
CSW01_RS17415	COG2390	Transcriptional regulator
CSW01_RS17430	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CSW01_RS17455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSW01_RS17480	COG0583	DNA-binding transcription factor activity
CSW01_RS17485	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CSW01_RS17530	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSW01_RS17575	COG1263	PTS System
CSW01_RS17575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW01_RS17580	COG1609	Transcriptional regulator
CSW01_RS17585	COG1621	beta-fructofuranosidase activity
CSW01_RS17590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSW01_RS17595	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CSW01_RS17605	COG2885	chlorophyll binding
CSW01_RS17610	COG0545	Peptidyl-prolyl cis-trans isomerase
CSW01_RS17615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSW01_RS17620	COG0840	transmembrane signaling receptor activity
CSW01_RS17630	COG3069	C4-dicarboxylate transmembrane transporter activity
CSW01_RS17635	COG1760	l-serine dehydratase
CSW01_RS17655	COG1609	Transcriptional regulator
CSW01_RS17660	COG2197	response regulator
CSW01_RS17665	COG3850	Histidine kinase
CSW01_RS17670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSW01_RS17680	COG0243	molybdopterin cofactor binding
CSW01_RS17700	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CSW01_RS17705	COG2197	response regulator
CSW01_RS17710	COG3851	Histidine kinase
CSW01_RS17715	COG2271	Major facilitator Superfamily
CSW01_RS17720	COG1840	ABC-type Fe3 transport system, periplasmic component
CSW01_RS17730	COG3842	ATPase activity
CSW01_RS17735	COG3243	poly(R)-hydroxyalkanoic acid synthase
CSW01_RS17745	COG0183	Belongs to the thiolase family
CSW01_RS17755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSW01_RS17760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSW01_RS17780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CSW01_RS17790	COG1979	alcohol dehydrogenase
CSW01_RS17805	COG4191	Histidine kinase
CSW01_RS17815	COG2271	Major facilitator Superfamily
CSW01_RS17820	COG0469	pyruvate kinase activity
CSW01_RS17825	COG0784	Response regulator, receiver
CSW01_RS17825	COG2205	protein histidine kinase activity
CSW01_RS17825	COG2198	Histidine kinase
CSW01_RS17830	COG1879	ABC-type sugar transport system periplasmic component
CSW01_RS17835	COG1803	Methylglyoxal synthase
CSW01_RS17840	COG1335	isochorismatase
CSW01_RS17845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CSW01_RS17860	COG0210	DNA helicase
CSW01_RS17865	COG1289	transmembrane transporter activity
CSW01_RS17895	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CSW01_RS17900	COG4149	molybdate abc transporter
CSW01_RS17905	COG0725	ABC transporter, periplasmic molybdate-binding protein
CSW01_RS17910	COG1492	cobalamin metabolic process
CSW01_RS17955	COG5002	protein histidine kinase activity
CSW01_RS17955	COG0784	Response regulator, receiver
CSW01_RS17960	COG1879	ABC-type sugar transport system periplasmic component
CSW01_RS17970	COG2827	Endonuclease containing a URI domain
CSW01_RS17985	COG2926	Belongs to the UPF0265 family
CSW01_RS18000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CSW01_RS18005	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CSW01_RS18010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CSW01_RS18015	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CSW01_RS18020	COG0247	lactate metabolic process
CSW01_RS18025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CSW01_RS18030	COG3118	belongs to the thioredoxin family
CSW01_RS18060	COG0583	DNA-binding transcription factor activity
CSW01_RS18065	COG4160	amino acid transport
CSW01_RS18070	COG4215	(ABC) transporter
CSW01_RS18075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW01_RS18080	COG1126	abc transporter atp-binding protein
CSW01_RS18090	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CSW01_RS18100	COG0494	nUDIX hydrolase
CSW01_RS18105	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CSW01_RS18115	COG1309	transcriptional regulator
CSW01_RS18120	COG0513	Belongs to the DEAD box helicase family
CSW01_RS18125	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CSW01_RS18135	COG0814	amino acid
CSW01_RS18140	COG0840	transmembrane signaling receptor activity
CSW01_RS18145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CSW01_RS18155	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CSW01_RS18165	COG1984	allophanate hydrolase subunit 2
CSW01_RS18180	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CSW01_RS18185	COG4181	ATPase activity
CSW01_RS18195	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CSW01_RS18200	COG1716	ATPase activity
CSW01_RS18200	COG5001	Diguanylate cyclase
CSW01_RS18215	COG0484	heat shock protein binding
CSW01_RS18255	COG0546	phosphoglycolate phosphatase activity
CSW01_RS18270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSW01_RS18275	COG1368	sulfuric ester hydrolase activity
CSW01_RS18285	COG0513	Belongs to the DEAD box helicase family
CSW01_RS18300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CSW01_RS18310	COG3046	protein related to deoxyribodipyrimidine photolyase
CSW01_RS18315	COG3397	chitin binding
CSW01_RS18320	COG3227	Zinc metalloprotease (Elastase)
CSW01_RS18330	COG0010	Belongs to the arginase family
CSW01_RS18335	COG1166	arginine decarboxylase activity
CSW01_RS18345	COG2239	Acts as a magnesium transporter
CSW01_RS18350	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CSW01_RS18355	COG0459	protein refolding
CSW01_RS18365	COG0527	aspartate kinase activity
CSW01_RS18370	COG0662	Cupin 2, conserved barrel domain protein
CSW01_RS18375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSW01_RS18380	COG0456	acetyltransferase
CSW01_RS18390	COG3186	Phenylalanine-4-hydroxylase
CSW01_RS18395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSW01_RS18415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CSW01_RS18440	COG1253	flavin adenine dinucleotide binding
CSW01_RS18445	COG1765	OsmC-like protein
CSW01_RS18470	COG0531	amino acid
CSW01_RS18485	COG3279	Response regulator of the LytR AlgR family
CSW01_RS18490	COG3275	phosphorelay sensor kinase activity
CSW01_RS18505	COG0577	efflux transmembrane transporter activity
CSW01_RS18505	COG1136	(ABC) transporter
CSW01_RS18510	COG1136	(ABC) transporter
CSW01_RS18525	COG4989	oxidoreductase activity
CSW01_RS18530	COG0366	Alpha amylase catalytic
CSW01_RS18540	COG2067	long-chain fatty acid transport protein
CSW01_RS18545	COG2267	carboxylic ester hydrolase activity
CSW01_RS18555	COG3227	Zinc metalloprotease (Elastase)
CSW01_RS18565	COG3047	cAMP biosynthetic process
CSW01_RS18575	COG1686	Belongs to the peptidase S11 family
CSW01_RS18580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW01_RS18585	COG1271	oxidase subunit
CSW01_RS18590	COG1294	oxidase, subunit
CSW01_RS18610	COG3048	D-serine ammonia-lyase activity
CSW01_RS18615	COG0583	DNA-binding transcription factor activity
CSW01_RS18665	COG1063	alcohol dehydrogenase
CSW01_RS18695	COG0346	lactoylglutathione lyase activity
CSW01_RS18715	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CSW01_RS18720	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CSW01_RS18725	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CSW01_RS18730	COG0363	glucosamine-6-phosphate deaminase activity
CSW01_RS18735	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CSW01_RS18760	COG1929	Belongs to the glycerate kinase type-1 family
CSW01_RS18765	COG2610	gluconate transmembrane transporter activity
CSW01_RS18770	COG3835	regulator
CSW01_RS18780	COG0748	coenzyme F420 binding
CSW01_RS18785	COG3721	Heme iron utilization protein
CSW01_RS18795	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CSW01_RS18800	COG0811	peptide transport
CSW01_RS18805	COG0848	biopolymer transport protein
CSW01_RS18810	COG4558	Periplasmic binding protein
CSW01_RS18815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW01_RS18820	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CSW01_RS18855	COG3217	Mosc domain protein beta barrel domain protein
CSW01_RS18855	COG0633	Ferredoxin
CSW01_RS18855	COG0633	Ferredoxin
CSW01_RS18855	COG3217	Mosc domain protein beta barrel domain protein
CSW01_RS18865	COG0418	dihydroorotase activity
CSW01_RS18875	COG3152	Membrane
CSW01_RS18885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CSW01_RS18890	COG2354	Protein conserved in bacteria
CSW01_RS18895	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CSW01_RS18900	COG1278	Cold shock
CSW01_RS18930	COG2199	diguanylate cyclase activity
CSW01_RS18935	COG1349	DNA-binding transcription factor activity
CSW01_RS18950	COG3833	ABC-type maltose transport systems, permease component
CSW01_RS18955	COG1175	transmembrane transport
CSW01_RS18965	COG3842	ATPase activity
CSW01_RS18970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW01_RS18985	COG0393	Putative heavy-metal-binding
CSW01_RS18995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSW01_RS19000	COG0784	Response regulator, receiver
CSW01_RS19000	COG0835	chemotaxis
CSW01_RS19005	COG1846	Transcriptional regulator
CSW01_RS19010	COG3706	GGDEF domain
CSW01_RS19050	COG0583	DNA-binding transcription factor activity
CSW01_RS19055	COG5001	Diguanylate cyclase
CSW01_RS19065	COG1741	Belongs to the pirin family
CSW01_RS19070	COG3123	guanosine phosphorylase activity
CSW01_RS19080	COG2211	Major facilitator Superfamily
CSW01_RS19090	COG0840	transmembrane signaling receptor activity
CSW01_RS19095	COG1067	ATP-dependent peptidase activity
CSW01_RS19105	COG4172	Belongs to the ABC transporter superfamily
CSW01_RS19130	COG0583	DNA-binding transcription factor activity
CSW01_RS19135	COG1620	l-lactate permease
CSW01_RS19150	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CSW01_RS19160	COG0840	transmembrane signaling receptor activity
CSW01_RS19170	COG0513	Belongs to the DEAD box helicase family
CSW01_RS19175	COG0583	DNA-binding transcription factor activity
CSW01_RS19185	COG1902	pentaerythritol trinitrate reductase activity
CSW01_RS19195	COG1132	(ABC) transporter
CSW01_RS19205	COG1902	pentaerythritol trinitrate reductase activity
CSW01_RS19215	COG1280	lysine exporter protein (LysE YggA)
CSW01_RS19220	COG2207	Transcriptional regulator
CSW01_RS19240	COG1846	Transcriptional regulator
CSW01_RS19245	COG1764	response to oxidative stress
CSW01_RS19250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CSW01_RS19255	COG0697	spore germination
CSW01_RS19265	COG0700	Nucleoside recognition
CSW01_RS19270	COG3366	ferrous iron transmembrane transporter activity
CSW01_RS19275	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CSW01_RS19285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSW01_RS19290	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CSW01_RS19295	COG2259	Doxx family
CSW01_RS19320	COG0363	glucosamine-6-phosphate deaminase activity
CSW01_RS19335	COG4580	involved in the transport of maltose and maltodextrins
CSW01_RS19350	COG0840	transmembrane signaling receptor activity
CSW01_RS19365	COG0840	transmembrane signaling receptor activity
CSW01_RS19375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CSW01_RS19380	COG1126	abc transporter atp-binding protein
CSW01_RS19390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW01_RS19395	COG4597	amino acid ABC transporter
CSW01_RS19400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSW01_RS19410	COG0739	heme binding
CSW01_RS19420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSW01_RS19420	COG2213	PTS system mannitol-specific
CSW01_RS19425	COG0246	Mannitol dehydrogenase
CSW01_RS19430	COG3722	fumarate hydratase activity
CSW01_RS19435	COG0673	inositol 2-dehydrogenase activity
CSW01_RS19465	COG2910	NAD(P)H-binding
CSW01_RS19475	COG0840	transmembrane signaling receptor activity
CSW01_RS19485	COG4221	oxidoreductase activity
CSW01_RS19495	COG1901	pseudouridine methyltransferase
CSW01_RS19510	COG0531	amino acid
CSW01_RS19515	COG1982	Orn Lys Arg decarboxylase major
CSW01_RS19550	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSW01_RS19575	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CSW01_RS19615	COG0745	RESPONSE REGULATOR receiver
CSW01_RS19640	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CSW01_RS19645	COG0840	transmembrane signaling receptor activity
CSW01_RS19650	COG0835	chemotaxis
CSW01_RS19655	COG0835	chemotaxis
CSW01_RS19660	COG2198	Histidine kinase
CSW01_RS19660	COG0643	Histidine kinase
CSW01_RS19680	COG0601	transmembrane transport
CSW01_RS19685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSW01_RS19695	COG2194	sulfuric ester hydrolase activity
CSW01_RS19700	COG0642	Histidine kinase
CSW01_RS19735	COG1444	tRNA N-acetyltransferase activity
CSW01_RS19740	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine