locus-tag	class	description
AP033_RS00005	COG2271	Major facilitator Superfamily
AP033_RS00010	COG0584	glycerophosphoryl diester phosphodiesterase
AP033_RS00020	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AP033_RS00030	COG1609	Transcriptional regulator
AP033_RS00035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AP033_RS00040	COG1879	ABC-type sugar transport system periplasmic component
AP033_RS00045	COG1172	Belongs to the binding-protein-dependent transport system permease family
AP033_RS00050	COG1129	ABC transporter
AP033_RS00055	COG1869	D-ribose catabolic process
AP033_RS00075	COG3501	Rhs element vgr protein
AP033_RS00075	COG3409	Peptidoglycan-binding domain 1 protein
AP033_RS00105	COG3829	transcription factor binding
AP033_RS00170	COG0564	pseudouridine synthase activity
AP033_RS00180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AP033_RS00185	COG2200	EAL domain
AP033_RS00185	COG2771	luxR family
AP033_RS00190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AP033_RS00195	COG0673	inositol 2-dehydrogenase activity
AP033_RS00200	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AP033_RS00235	COG1342	Belongs to the UPF0251 family
AP033_RS00250	COG1301	dicarboxylic acid transport
AP033_RS00275	COG2814	Major facilitator Superfamily
AP033_RS00280	COG0583	DNA-binding transcription factor activity
AP033_RS00285	COG3300	MHYT domain
AP033_RS00285	COG5001	Diguanylate cyclase
AP033_RS00290	COG0739	heme binding
AP033_RS00300	COG0659	secondary active sulfate transmembrane transporter activity
AP033_RS00305	COG3314	Sporulation integral membrane protein YlbJ
AP033_RS00320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AP033_RS00325	COG0581	inorganic phosphate transmembrane transporter activity
AP033_RS00330	COG0573	inorganic phosphate transmembrane transporter activity
AP033_RS00335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AP033_RS00365	COG1770	oligopeptidase
AP033_RS00370	COG0513	Belongs to the DEAD box helicase family
AP033_RS00385	COG1376	ErfK ybiS ycfS ynhG family protein
AP033_RS00385	COG1388	LysM domain
AP033_RS00390	COG0415	Belongs to the DNA photolyase family
AP033_RS00400	COG3272	Protein of unknown function (DUF1722)
AP033_RS00410	COG0813	purine-nucleoside phosphorylase activity
AP033_RS00435	COG1566	PFAM secretion protein HlyD family protein
AP033_RS00455	COG0786	glutamate:sodium symporter activity
AP033_RS00470	COG1999	signal sequence binding
AP033_RS00480	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AP033_RS00485	COG0671	phosphoesterase, PA-phosphatase related
AP033_RS00530	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AP033_RS00535	COG0471	metal ion transport
AP033_RS00565	COG4104	PAAR repeat-containing protein
AP033_RS00570	COG3501	Rhs element vgr protein
AP033_RS00580	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AP033_RS00585	COG1640	4-alpha-glucanotransferase
AP033_RS00590	COG0058	SHG alpha-glucan phosphorylase activity
AP033_RS00595	COG2909	trisaccharide binding
AP033_RS00615	COG2084	Dehydrogenase
AP033_RS00620	COG0217	transcriptional regulatory protein
AP033_RS00655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AP033_RS00660	COG1444	tRNA N-acetyltransferase activity
AP033_RS00695	COG0642	Histidine kinase
AP033_RS00700	COG2194	sulfuric ester hydrolase activity
AP033_RS00705	COG4608	Belongs to the ABC transporter superfamily
AP033_RS00710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AP033_RS00715	COG0601	transmembrane transport
AP033_RS00735	COG0643	Histidine kinase
AP033_RS00735	COG2198	Histidine kinase
AP033_RS00740	COG0835	chemotaxis
AP033_RS00745	COG0835	chemotaxis
AP033_RS00750	COG0840	transmembrane signaling receptor activity
AP033_RS00755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AP033_RS00780	COG0745	RESPONSE REGULATOR receiver
AP033_RS00825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AP033_RS00850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AP033_RS00880	COG1982	Orn Lys Arg decarboxylase major
AP033_RS00885	COG0531	amino acid
AP033_RS00895	COG1901	pseudouridine methyltransferase
AP033_RS00905	COG4221	oxidoreductase activity
AP033_RS00910	COG0840	transmembrane signaling receptor activity
AP033_RS00920	COG2910	NAD(P)H-binding
AP033_RS00930	COG1335	isochorismatase
AP033_RS00945	COG0697	spore germination
AP033_RS00970	COG0673	inositol 2-dehydrogenase activity
AP033_RS00975	COG3722	fumarate hydratase activity
AP033_RS00980	COG0246	Mannitol dehydrogenase
AP033_RS00985	COG2213	PTS system mannitol-specific
AP033_RS00985	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AP033_RS00995	COG0739	heme binding
AP033_RS01005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AP033_RS01010	COG4597	amino acid ABC transporter
AP033_RS01015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AP033_RS01025	COG1126	abc transporter atp-binding protein
AP033_RS01030	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AP033_RS01040	COG0840	transmembrane signaling receptor activity
AP033_RS01055	COG0840	transmembrane signaling receptor activity
AP033_RS01070	COG4580	involved in the transport of maltose and maltodextrins
AP033_RS01085	COG0363	glucosamine-6-phosphate deaminase activity
AP033_RS01110	COG2259	Doxx family
AP033_RS01115	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AP033_RS01120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AP033_RS01130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AP033_RS01135	COG3366	ferrous iron transmembrane transporter activity
AP033_RS01140	COG0700	Nucleoside recognition
AP033_RS01150	COG0697	spore germination
AP033_RS01155	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AP033_RS01160	COG1764	response to oxidative stress
AP033_RS01165	COG1846	Transcriptional regulator
AP033_RS01185	COG2207	Transcriptional regulator
AP033_RS01190	COG1280	lysine exporter protein (LysE YggA)
AP033_RS01200	COG1902	pentaerythritol trinitrate reductase activity
AP033_RS01210	COG1132	(ABC) transporter
AP033_RS01220	COG1902	pentaerythritol trinitrate reductase activity
AP033_RS01230	COG0583	DNA-binding transcription factor activity
AP033_RS01235	COG0513	Belongs to the DEAD box helicase family
AP033_RS01255	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AP033_RS01270	COG1620	l-lactate permease
AP033_RS01275	COG0583	DNA-binding transcription factor activity
AP033_RS01295	COG4172	Belongs to the ABC transporter superfamily
AP033_RS01305	COG1067	ATP-dependent peptidase activity
AP033_RS01320	COG2211	Major facilitator Superfamily
AP033_RS01330	COG3123	guanosine phosphorylase activity
AP033_RS01335	COG1741	Belongs to the pirin family
AP033_RS01345	COG5001	Diguanylate cyclase
AP033_RS01350	COG0583	DNA-binding transcription factor activity
AP033_RS01390	COG3706	GGDEF domain
AP033_RS01395	COG1846	Transcriptional regulator
AP033_RS01400	COG0784	Response regulator, receiver
AP033_RS01400	COG0835	chemotaxis
AP033_RS01405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AP033_RS01415	COG0393	Putative heavy-metal-binding
AP033_RS01430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AP033_RS01435	COG3842	ATPase activity
AP033_RS01445	COG1175	transmembrane transport
AP033_RS01450	COG3833	ABC-type maltose transport systems, permease component
AP033_RS01465	COG1349	DNA-binding transcription factor activity
AP033_RS01470	COG2199	diguanylate cyclase activity
AP033_RS01495	COG1278	Cold shock
AP033_RS01500	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AP033_RS01505	COG2354	Protein conserved in bacteria
AP033_RS01510	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AP033_RS01520	COG3152	Membrane
AP033_RS01530	COG0418	dihydroorotase activity
AP033_RS01535	COG0633	Ferredoxin
AP033_RS01535	COG0633	Ferredoxin
AP033_RS01535	COG3217	Mosc domain protein beta barrel domain protein
AP033_RS01535	COG3217	Mosc domain protein beta barrel domain protein
AP033_RS01570	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AP033_RS01575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AP033_RS01580	COG4558	Periplasmic binding protein
AP033_RS01585	COG0848	biopolymer transport protein
AP033_RS01590	COG0811	peptide transport
AP033_RS01595	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AP033_RS01605	COG3721	Heme iron utilization protein
AP033_RS01610	COG0748	coenzyme F420 binding
AP033_RS01620	COG3835	regulator
AP033_RS01625	COG2610	gluconate transmembrane transporter activity
AP033_RS01630	COG1929	Belongs to the glycerate kinase type-1 family
AP033_RS01655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AP033_RS01660	COG0363	glucosamine-6-phosphate deaminase activity
AP033_RS01665	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AP033_RS01670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AP033_RS01675	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AP033_RS01695	COG0346	lactoylglutathione lyase activity
AP033_RS01705	COG2873	o-acetylhomoserine
AP033_RS01715	COG1063	alcohol dehydrogenase
AP033_RS01765	COG1802	Transcriptional regulator
AP033_RS01765	COG4626	Terminase
AP033_RS01790	COG1278	Cold shock
AP033_RS01820	COG0640	Transcriptional regulator
AP033_RS01825	COG0798	PFAM Bile acid sodium symporter
AP033_RS01935	COG2610	gluconate transmembrane transporter activity
AP033_RS01940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AP033_RS01945	COG3622	Belongs to the hyi family
AP033_RS01950	COG0235	Class ii aldolase
AP033_RS01955	COG3395	kinase activity
AP033_RS01960	COG2084	Dehydrogenase
AP033_RS01965	COG1349	DNA-binding transcription factor activity
AP033_RS01975	COG3039	Transposase
AP033_RS01980	COG3048	D-serine ammonia-lyase activity
AP033_RS01990	COG1294	oxidase, subunit
AP033_RS01995	COG1271	oxidase subunit
AP033_RS02000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AP033_RS02005	COG1686	Belongs to the peptidase S11 family
AP033_RS02015	COG3047	cAMP biosynthetic process
AP033_RS02025	COG3227	Zinc metalloprotease (Elastase)
AP033_RS02035	COG2267	carboxylic ester hydrolase activity
AP033_RS02040	COG2067	long-chain fatty acid transport protein
AP033_RS02050	COG0366	Alpha amylase catalytic
AP033_RS02055	COG4989	oxidoreductase activity
AP033_RS02070	COG1136	(ABC) transporter
AP033_RS02075	COG0577	efflux transmembrane transporter activity
AP033_RS02075	COG1136	(ABC) transporter
AP033_RS02090	COG3275	phosphorelay sensor kinase activity
AP033_RS02095	COG3279	Response regulator of the LytR AlgR family
AP033_RS02115	COG0531	amino acid
AP033_RS02145	COG1765	OsmC-like protein
AP033_RS02150	COG1253	flavin adenine dinucleotide binding
AP033_RS02175	COG2264	protein methyltransferase activity
AP033_RS02190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AP033_RS02195	COG3186	Phenylalanine-4-hydroxylase
AP033_RS02200	COG2154	pterin-4-alpha-carbinolamine dehydratase
AP033_RS02205	COG0456	acetyltransferase
AP033_RS02210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AP033_RS02215	COG0662	Cupin 2, conserved barrel domain protein
AP033_RS02220	COG0527	aspartate kinase activity
AP033_RS02230	COG0459	protein refolding
AP033_RS02235	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AP033_RS02240	COG2239	Acts as a magnesium transporter
AP033_RS02250	COG1166	arginine decarboxylase activity
AP033_RS02255	COG0010	Belongs to the arginase family
AP033_RS02265	COG3227	Zinc metalloprotease (Elastase)
AP033_RS02270	COG3397	chitin binding
AP033_RS02275	COG3046	protein related to deoxyribodipyrimidine photolyase
AP033_RS02285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AP033_RS02300	COG0513	Belongs to the DEAD box helicase family
AP033_RS02310	COG1368	sulfuric ester hydrolase activity
AP033_RS02315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AP033_RS02330	COG0546	phosphoglycolate phosphatase activity
AP033_RS02380	COG1328	CTP reductase activity
AP033_RS02385	COG0602	queuosine metabolic process
AP033_RS02395	COG0189	ligase activity
AP033_RS02395	COG4067	protein conserved in archaea
AP033_RS02400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AP033_RS02400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AP033_RS02400	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AP033_RS02405	COG1105	Belongs to the carbohydrate kinase PfkB family
AP033_RS02415	COG1609	Transcriptional regulator
AP033_RS02420	COG0420	3'-5' exonuclease activity
AP033_RS02425	COG0419	ATPase involved in DNA repair
AP033_RS02430	COG0784	Response regulator, receiver
AP033_RS02430	COG2205	protein histidine kinase activity
AP033_RS02435	COG0156	8-amino-7-oxononanoate synthase activity
AP033_RS02445	COG0038	chloride channel
AP033_RS02450	COG0523	cobalamin synthesis protein
AP033_RS02460	COG3158	transport of potassium into the cell
AP033_RS02465	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AP033_RS02465	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AP033_RS02465	COG1013	pyruvate-flavodoxin oxidoreductase activity
AP033_RS02465	COG0674	pyruvate-flavodoxin oxidoreductase activity
AP033_RS02470	COG2205	protein histidine kinase activity
AP033_RS02475	COG0745	RESPONSE REGULATOR receiver
AP033_RS02480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AP033_RS02485	COG0586	Pfam SNARE associated Golgi protein
AP033_RS02495	COG2200	EAL domain
AP033_RS02505	COG3038	cytochrome b561
AP033_RS02515	COG2116	formate transmembrane transporter activity
AP033_RS02520	COG0583	DNA-binding transcription factor activity
AP033_RS02530	COG3593	DNA synthesis involved in DNA repair
AP033_RS02535	COG0737	Belongs to the 5'-nucleotidase family
AP033_RS02540	COG0861	Integral membrane protein TerC family
AP033_RS02550	COG2824	Alkylphosphonate utilization operon protein PhnA
AP033_RS02585	COG2199	diguanylate cyclase activity
AP033_RS02605	COG3706	GGDEF domain
AP033_RS02620	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AP033_RS02625	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AP033_RS02635	COG0745	RESPONSE REGULATOR receiver
AP033_RS02650	COG3140	Belongs to the UPF0181 family
AP033_RS02655	COG0023	Translation Initiation Factor
AP033_RS02675	COG0045	succinate-CoA ligase (ADP-forming) activity
AP033_RS02675	COG1042	CoA-binding domain protein
AP033_RS02675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AP033_RS02680	COG0583	DNA-binding transcription factor activity
AP033_RS02685	COG1629	transport
AP033_RS02685	COG4771	TonB-dependent receptor
AP033_RS02705	COG2050	protein possibly involved in aromatic compounds catabolism
AP033_RS02725	COG0625	glutathione transferase activity
AP033_RS02740	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AP033_RS02745	COG4172	Belongs to the ABC transporter superfamily
AP033_RS02750	COG4239	(ABC) transporter, permease
AP033_RS02755	COG4174	ABC transporter (Permease)
AP033_RS02760	COG4166	transmembrane transport
AP033_RS02785	COG3104	oligopeptide transport
AP033_RS02805	COG3842	ATPase activity
AP033_RS02810	COG1840	ABC-type Fe3 transport system, periplasmic component
AP033_RS02815	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AP033_RS02820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AP033_RS02825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AP033_RS02830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AP033_RS02835	COG1011	Hydrolase
AP033_RS02845	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AP033_RS02850	COG1970	mechanosensitive ion channel activity
AP033_RS02855	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AP033_RS02860	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AP033_RS02860	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AP033_RS02865	COG0302	gtp cyclohydrolase
AP033_RS02875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AP033_RS02885	COG2897	thiosulfate sulfurtransferase activity
AP033_RS02895	COG2390	Transcriptional regulator
AP033_RS02910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AP033_RS02940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AP033_RS02965	COG0583	DNA-binding transcription factor activity
AP033_RS02970	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AP033_RS03015	COG0446	pyridine nucleotide-disulphide oxidoreductase
AP033_RS03060	COG1263	PTS System
AP033_RS03060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AP033_RS03065	COG1609	Transcriptional regulator
AP033_RS03070	COG1621	beta-fructofuranosidase activity
AP033_RS03075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AP033_RS03080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AP033_RS03085	COG0840	transmembrane signaling receptor activity
AP033_RS03090	COG2885	chlorophyll binding
AP033_RS03095	COG0545	Peptidyl-prolyl cis-trans isomerase
AP033_RS03100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AP033_RS03105	COG0840	transmembrane signaling receptor activity
AP033_RS03115	COG3069	C4-dicarboxylate transmembrane transporter activity
AP033_RS03120	COG1760	l-serine dehydratase
AP033_RS03145	COG1609	Transcriptional regulator
AP033_RS03150	COG2197	response regulator
AP033_RS03155	COG3850	Histidine kinase
AP033_RS03160	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AP033_RS03170	COG0243	molybdopterin cofactor binding
AP033_RS03190	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AP033_RS03195	COG2197	response regulator
AP033_RS03200	COG3851	Histidine kinase
AP033_RS03205	COG2271	Major facilitator Superfamily
AP033_RS03210	COG1840	ABC-type Fe3 transport system, periplasmic component
AP033_RS03220	COG3842	ATPase activity
AP033_RS03225	COG3243	poly(R)-hydroxyalkanoic acid synthase
AP033_RS03235	COG0183	Belongs to the thiolase family
AP033_RS03245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AP033_RS03250	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AP033_RS03270	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AP033_RS03280	COG1979	alcohol dehydrogenase
AP033_RS03295	COG4191	Histidine kinase
AP033_RS03305	COG2271	Major facilitator Superfamily
AP033_RS03310	COG0469	pyruvate kinase activity
AP033_RS03315	COG2205	protein histidine kinase activity
AP033_RS03315	COG2198	Histidine kinase
AP033_RS03315	COG0784	Response regulator, receiver
AP033_RS03320	COG1879	ABC-type sugar transport system periplasmic component
AP033_RS03325	COG1803	Methylglyoxal synthase
AP033_RS03330	COG1335	isochorismatase
AP033_RS03335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AP033_RS03350	COG0210	DNA helicase
AP033_RS03355	COG1289	transmembrane transporter activity
AP033_RS03385	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AP033_RS03390	COG4149	molybdate abc transporter
AP033_RS03395	COG0725	ABC transporter, periplasmic molybdate-binding protein
AP033_RS03400	COG1492	cobalamin metabolic process
AP033_RS03405	COG3039	Transposase
AP033_RS03410	COG3039	Transposase
AP033_RS03445	COG0784	Response regulator, receiver
AP033_RS03445	COG5002	protein histidine kinase activity
AP033_RS03450	COG1879	ABC-type sugar transport system periplasmic component
AP033_RS03460	COG2827	Endonuclease containing a URI domain
AP033_RS03475	COG2926	Belongs to the UPF0265 family
AP033_RS03495	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AP033_RS03505	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AP033_RS03515	COG0247	lactate metabolic process
AP033_RS03520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AP033_RS03525	COG3118	belongs to the thioredoxin family
AP033_RS03550	COG4160	amino acid transport
AP033_RS03555	COG4215	(ABC) transporter
AP033_RS03560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AP033_RS03565	COG1126	abc transporter atp-binding protein
AP033_RS03575	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AP033_RS03585	COG0494	nUDIX hydrolase
AP033_RS03590	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AP033_RS03600	COG1309	transcriptional regulator
AP033_RS03605	COG0513	Belongs to the DEAD box helicase family
AP033_RS03610	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AP033_RS03620	COG0814	amino acid
AP033_RS03625	COG0840	transmembrane signaling receptor activity
AP033_RS03630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AP033_RS03640	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AP033_RS03650	COG1984	allophanate hydrolase subunit 2
AP033_RS03665	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AP033_RS03670	COG4181	ATPase activity
AP033_RS03680	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AP033_RS03685	COG5001	Diguanylate cyclase
AP033_RS03685	COG1716	ATPase activity
AP033_RS03700	COG0484	heat shock protein binding
AP033_RS03720	COG0346	lactoylglutathione lyase activity
AP033_RS03835	COG3039	Transposase
AP033_RS03875	COG0346	lactoylglutathione lyase activity
AP033_RS03890	COG0110	maltose O-acetyltransferase activity
AP033_RS03895	COG3039	Transposase
AP033_RS03920	COG4977	sequence-specific DNA binding
AP033_RS03925	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AP033_RS03975	COG3040	lipid binding
AP033_RS04075	COG3039	Transposase
AP033_RS04095	COG0346	lactoylglutathione lyase activity
AP033_RS04125	COG0384	phenazine biosynthesis protein PhzF
AP033_RS04130	COG3093	addiction module antidote protein HigA
AP033_RS04135	COG3549	Plasmid maintenance system killer
AP033_RS04215	COG3039	Transposase
AP033_RS04230	COG4977	sequence-specific DNA binding
AP033_RS04260	COG3039	Transposase
AP033_RS04270	COG1619	proteins homologs of microcin C7 resistance protein MccF
AP033_RS04285	COG0384	phenazine biosynthesis protein PhzF
AP033_RS04335	COG0346	lactoylglutathione lyase activity
AP033_RS04375	COG0346	lactoylglutathione lyase activity
AP033_RS04415	COG5642	Protein of unknown function (DUF2384)
AP033_RS04525	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AP033_RS04530	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AP033_RS04540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AP033_RS04690	COG3772	lysozyme
AP033_RS04785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AP033_RS04795	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AP033_RS04800	COG0509	glycine decarboxylation via glycine cleavage system
AP033_RS04805	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AP033_RS04805	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AP033_RS04830	COG1686	Belongs to the peptidase S11 family
AP033_RS04845	COG2814	Major facilitator Superfamily
AP033_RS04860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AP033_RS04885	COG5002	protein histidine kinase activity
AP033_RS04890	COG0745	RESPONSE REGULATOR receiver
AP033_RS04910	COG0366	Alpha amylase catalytic
AP033_RS04915	COG3038	cytochrome b561
AP033_RS04945	COG0561	phosphatase activity
AP033_RS04950	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AP033_RS04955	COG3623	hexulose-6-phosphate isomerase
AP033_RS04965	COG0745	RESPONSE REGULATOR receiver
AP033_RS04985	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AP033_RS05000	COG2207	Transcriptional regulator
AP033_RS05005	COG4604	ABC transporter, ATP-binding protein
AP033_RS05010	COG4605	iron ion homeostasis
AP033_RS05015	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AP033_RS05040	COG5380	lipid catabolic process
AP033_RS05045	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AP033_RS05050	COG0840	transmembrane signaling receptor activity
AP033_RS05060	COG3240	lipase activity
AP033_RS05065	COG3706	GGDEF domain
AP033_RS05080	COG2814	Major facilitator Superfamily
AP033_RS05085	COG1757	Na H antiporter
AP033_RS05095	COG4191	Histidine kinase
AP033_RS05095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AP033_RS05100	COG3437	response regulator, receiver
AP033_RS05100	COG0784	Response regulator, receiver
AP033_RS05105	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AP033_RS05110	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AP033_RS05115	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AP033_RS05120	COG0513	Belongs to the DEAD box helicase family
AP033_RS05130	COG0516	GMP reductase activity
AP033_RS05145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AP033_RS05155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AP033_RS05160	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AP033_RS05160	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AP033_RS05185	COG3036	rescue of stalled ribosome
AP033_RS05190	COG1278	Cold shock
AP033_RS05195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AP033_RS05195	COG1017	nitric oxide dioxygenase activity
AP033_RS05200	COG3604	Transcriptional regulator
AP033_RS05210	COG2195	Cleaves the N-terminal amino acid of tripeptides
AP033_RS05215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AP033_RS05230	COG0840	transmembrane signaling receptor activity
AP033_RS05235	COG0714	Associated with various cellular activities
AP033_RS05255	COG2304	oxidoreductase activity
AP033_RS05270	COG1278	Cold shock
AP033_RS05275	COG5001	Diguanylate cyclase
AP033_RS05275	COG5002	protein histidine kinase activity
AP033_RS05285	COG3530	Putative quorum-sensing-regulated virulence factor
AP033_RS05300	COG0814	amino acid
AP033_RS05305	COG0589	response to stress
AP033_RS05315	COG2111	Na H antiporter
AP033_RS05315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AP033_RS05320	COG1006	Multisubunit Na H antiporter MnhC subunit
AP033_RS05325	COG0651	ATP synthesis coupled electron transport
AP033_RS05330	COG1863	multisubunit Na H antiporter MnhE subunit
AP033_RS05335	COG2212	antiporter activity
AP033_RS05340	COG1320	monovalent cation:proton antiporter activity
AP033_RS05345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AP033_RS05345	COG1017	nitric oxide dioxygenase activity
AP033_RS05350	COG0242	peptide deformylase activity
AP033_RS05360	COG0579	oxidoreductase
AP033_RS05615	COG0673	inositol 2-dehydrogenase activity
AP033_RS05690	COG1301	dicarboxylic acid transport
AP033_RS05700	COG2814	Major facilitator Superfamily
AP033_RS05710	COG5002	protein histidine kinase activity
AP033_RS05710	COG5001	Diguanylate cyclase
AP033_RS05840	COG1770	oligopeptidase
AP033_RS06235	COG0643	Histidine kinase
AP033_RS06235	COG2198	Histidine kinase
AP033_RS06240	COG2198	Histidine kinase
AP033_RS06240	COG0643	Histidine kinase
AP033_RS06480	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AP033_RS06480	COG2213	PTS system mannitol-specific
AP033_RS06500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AP033_RS06515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AP033_RS06815	COG1067	ATP-dependent peptidase activity
AP033_RS07475	COG0366	Alpha amylase catalytic
AP033_RS07490	COG4989	oxidoreductase activity
AP033_RS08010	COG0737	Belongs to the 5'-nucleotidase family
AP033_RS08180	COG0045	succinate-CoA ligase (ADP-forming) activity
AP033_RS08180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AP033_RS08180	COG1042	CoA-binding domain protein
AP033_RS08300	COG2188	Transcriptional regulator
AP033_RS08370	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AP033_RS08575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AP033_RS08625	COG3069	C4-dicarboxylate transmembrane transporter activity
AP033_RS08640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AP033_RS08755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AP033_RS08975	COG0784	Response regulator, receiver
AP033_RS08975	COG5002	protein histidine kinase activity
AP033_RS09895	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AP033_RS09895	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AP033_RS09965	COG5002	protein histidine kinase activity
AP033_RS10120	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AP033_RS10230	COG1017	nitric oxide dioxygenase activity
AP033_RS10230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AP033_RS10320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AP033_RS10585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AP033_RS11200	COG1185	polyribonucleotide nucleotidyltransferase activity
AP033_RS11240	COG3153	acetyltransferase
AP033_RS11320	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AP033_RS11345	COG0728	peptidoglycan biosynthetic process
AP033_RS11400	COG1472	Belongs to the glycosyl hydrolase 3 family
AP033_RS11500	COG0542	response to heat
AP033_RS12330	COG0047	phosphoribosylformylglycinamidine synthase activity
AP033_RS12330	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AP033_RS12740	COG1466	dna polymerase III delta subunit
AP033_RS12760	COG0495	leucyl-tRNA aminoacylation
AP033_RS12775	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AP033_RS12785	COG4535	Mg2 and Co2 transporter CorC
AP033_RS12800	COG1702	phosphate starvation-inducible protein PhoH
AP033_RS12810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AP033_RS12815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AP033_RS12960	COG3104	oligopeptide transport
AP033_RS12980	COG0367	asparagine synthase
AP033_RS13185	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AP033_RS13185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AP033_RS13235	COG2067	long-chain fatty acid transport protein
AP033_RS13895	COG0500	methyltransferase
AP033_RS13935	COG0135	phosphoribosylanthranilate isomerase activity
AP033_RS13935	COG0134	indole-3-glycerol-phosphate synthase activity
AP033_RS13975	COG4988	ABC transporter
AP033_RS14235	COG0295	cytidine deaminase activity
AP033_RS14420	COG0726	polysaccharide deacetylase
AP033_RS14560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AP033_RS14585	COG2990	Protein conserved in bacteria
AP033_RS14740	COG5002	protein histidine kinase activity
AP033_RS14740	COG2205	protein histidine kinase activity
AP033_RS14740	COG0784	Response regulator, receiver
AP033_RS15015	COG0513	Belongs to the DEAD box helicase family
AP033_RS15225	COG2274	protein secretion by the type I secretion system
AP033_RS15270	COG3064	Membrane
AP033_RS15270	COG1073	alpha beta
AP033_RS15270	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AP033_RS15280	COG3064	Membrane
AP033_RS15280	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AP033_RS15280	COG1073	alpha beta
AP033_RS15295	COG3064	Membrane
AP033_RS15295	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AP033_RS15295	COG1073	alpha beta
AP033_RS15300	COG1073	alpha beta
AP033_RS15300	COG3064	Membrane
AP033_RS15300	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AP033_RS15310	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AP033_RS15310	COG1073	alpha beta
AP033_RS15310	COG3064	Membrane
AP033_RS15460	COG3008	intermembrane lipid transfer
AP033_RS15470	COG3008	intermembrane lipid transfer
AP033_RS15535	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AP033_RS15590	COG3383	formate dehydrogenase (NAD+) activity
AP033_RS15590	COG0243	molybdopterin cofactor binding
AP033_RS15860	COG0114	fumarate hydratase activity
AP033_RS16030	COG3290	protein histidine kinase activity
AP033_RS16315	COG2205	protein histidine kinase activity
AP033_RS16315	COG0784	Response regulator, receiver
AP033_RS16315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AP033_RS16315	COG2198	Histidine kinase
AP033_RS16655	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AP033_RS16955	COG3829	transcription factor binding
AP033_RS17165	COG0708	Exodeoxyribonuclease III
AP033_RS17170	COG0708	Exodeoxyribonuclease III
AP033_RS17340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AP033_RS17450	COG1674	ftsk spoiiie
AP033_RS17650	COG0243	molybdopterin cofactor binding
AP033_RS17680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AP033_RS18295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AP033_RS18920	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AP033_RS18930	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA