locus-tag	class	description
GPY07_RS00005	COG1271	oxidase subunit
GPY07_RS00010	COG1294	oxidase, subunit
GPY07_RS00015	COG1136	(ABC) transporter
GPY07_RS00015	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPY07_RS00020	COG1136	(ABC) transporter
GPY07_RS00020	COG0577	efflux transmembrane transporter activity
GPY07_RS00025	COG1136	(ABC) transporter
GPY07_RS00025	COG0577	efflux transmembrane transporter activity
GPY07_RS00045	COG0583	DNA-binding transcription factor activity
GPY07_RS00050	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GPY07_RS00055	COG2723	6-phospho-beta-galactosidase activity
GPY07_RS00060	COG1609	Transcriptional regulator
GPY07_RS00065	COG0251	oxidation-reduction process
GPY07_RS00070	COG2731	YhcH YjgK YiaL family protein
GPY07_RS00075	COG0584	glycerophosphoryl diester phosphodiesterase
GPY07_RS00080	COG1349	DNA-binding transcription factor activity
GPY07_RS00085	COG3842	ATPase activity
GPY07_RS00090	COG0395	ABC-type sugar transport system, permease component
GPY07_RS00095	COG1175	transmembrane transport
GPY07_RS00110	COG0811	peptide transport
GPY07_RS00115	COG0811	peptide transport
GPY07_RS00120	COG0848	biopolymer transport protein
GPY07_RS00125	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GPY07_RS00135	COG1793	dna ligase
GPY07_RS00145	COG0534	Mate efflux family protein
GPY07_RS00165	COG0791	NLP P60 protein
GPY07_RS00170	COG0840	transmembrane signaling receptor activity
GPY07_RS00185	COG1940	carbohydrate kinase activity
GPY07_RS00215	COG0746	molybdenum cofactor guanylyltransferase activity
GPY07_RS00220	COG3842	ATPase activity
GPY07_RS00225	COG4662	Binding-protein-dependent transport system inner membrane component
GPY07_RS00235	COG2204	response regulator
GPY07_RS00240	COG3852	Histidine kinase
GPY07_RS00245	COG0488	(ABC) transporter
GPY07_RS00250	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPY07_RS00280	COG3383	formate dehydrogenase (NAD+) activity
GPY07_RS00280	COG0243	molybdopterin cofactor binding
GPY07_RS00285	COG0437	4 iron, 4 sulfur cluster binding
GPY07_RS00300	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GPY07_RS00310	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY07_RS00325	COG2996	Protein conserved in bacteria
GPY07_RS00330	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GPY07_RS00330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPY07_RS00335	COG3008	intermembrane lipid transfer
GPY07_RS00340	COG2995	paraquat-inducible protein a
GPY07_RS00345	COG1132	(ABC) transporter
GPY07_RS00350	COG1956	GAF domain-containing protein
GPY07_RS00355	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GPY07_RS00370	COG0308	aminopeptidase N
GPY07_RS00385	COG0167	dihydroorotate dehydrogenase activity
GPY07_RS00395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY07_RS00395	COG0116	Belongs to the methyltransferase superfamily
GPY07_RS00420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY07_RS00425	COG1067	ATP-dependent peptidase activity
GPY07_RS00430	COG3120	sequence-specific DNA binding
GPY07_RS00510	COG1476	TRANSCRIPTIONal
GPY07_RS00540	COG4128	Pfam Zonular occludens toxin
GPY07_RS00555	COG1476	TRANSCRIPTIONal
GPY07_RS00575	COG1476	TRANSCRIPTIONal
GPY07_RS00605	COG4128	Pfam Zonular occludens toxin
GPY07_RS00620	COG1476	TRANSCRIPTIONal
GPY07_RS00640	COG3064	Membrane
GPY07_RS00640	COG1073	alpha beta
GPY07_RS00640	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GPY07_RS00645	COG2994	toxin metabolic process
GPY07_RS00670	COG2205	protein histidine kinase activity
GPY07_RS00670	COG0784	Response regulator, receiver
GPY07_RS00685	COG3278	Belongs to the heme-copper respiratory oxidase family
GPY07_RS00700	COG2010	Cytochrome c
GPY07_RS00710	COG2217	Heavy metal translocating P-type atpase
GPY07_RS00725	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY07_RS00730	COG0589	response to stress
GPY07_RS00735	COG0037	tRNA processing
GPY07_RS00755	COG3842	ATPase activity
GPY07_RS00760	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPY07_RS00765	COG1177	transmembrane transport
GPY07_RS00770	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY07_RS00775	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY07_RS00790	COG1115	amino acid carrier protein
GPY07_RS00795	COG1280	lysine exporter protein (LysE YggA)
GPY07_RS00820	COG3501	Rhs element vgr protein
GPY07_RS00830	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GPY07_RS00835	COG0840	transmembrane signaling receptor activity
GPY07_RS00840	COG2814	Major facilitator Superfamily
GPY07_RS00845	COG1566	PFAM secretion protein HlyD family protein
GPY07_RS00850	COG1538	Outer membrane efflux protein
GPY07_RS00860	COG0513	Belongs to the DEAD box helicase family
GPY07_RS00870	COG0840	transmembrane signaling receptor activity
GPY07_RS00875	COG3290	protein histidine kinase activity
GPY07_RS00875	COG0840	transmembrane signaling receptor activity
GPY07_RS00880	COG0835	chemotaxis
GPY07_RS00885	COG2201	protein-glutamate methylesterase activity
GPY07_RS00895	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPY07_RS00905	COG2198	Histidine kinase
GPY07_RS00905	COG0643	Histidine kinase
GPY07_RS00925	COG2076	Multidrug Resistance protein
GPY07_RS00930	COG0415	Belongs to the DNA photolyase family
GPY07_RS00935	COG0477	Major facilitator Superfamily
GPY07_RS00940	COG0583	DNA-binding transcription factor activity
GPY07_RS00950	COG0095	Lipoate-protein ligase
GPY07_RS00955	COG0443	Heat shock 70 kDa protein
GPY07_RS00965	COG1643	Atp-dependent helicase
GPY07_RS01000	COG0443	Heat shock 70 kDa protein
GPY07_RS01005	COG0443	Heat shock 70 kDa protein
GPY07_RS01010	COG3706	GGDEF domain
GPY07_RS01040	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPY07_RS01045	COG0602	queuosine metabolic process
GPY07_RS01050	COG0561	phosphatase activity
GPY07_RS01060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY07_RS01065	COG4597	amino acid ABC transporter
GPY07_RS01070	COG0765	amino acid transport
GPY07_RS01075	COG1126	abc transporter atp-binding protein
GPY07_RS01080	COG0670	Belongs to the BI1 family
GPY07_RS01085	COG2920	part of a sulfur-relay system
GPY07_RS01090	COG1254	Belongs to the acylphosphatase family
GPY07_RS01095	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY07_RS01100	COG3706	GGDEF domain
GPY07_RS01115	COG3437	response regulator, receiver
GPY07_RS01120	COG0625	glutathione transferase activity
GPY07_RS01130	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GPY07_RS01140	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY07_RS01170	COG0372	Belongs to the citrate synthase family
GPY07_RS01175	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPY07_RS01180	COG2186	Transcriptional regulator
GPY07_RS01215	COG1129	ABC transporter
GPY07_RS01240	COG0745	RESPONSE REGULATOR receiver
GPY07_RS01245	COG2205	protein histidine kinase activity
GPY07_RS01250	COG3713	MltA-interacting MipA family protein
GPY07_RS01255	COG2990	Protein conserved in bacteria
GPY07_RS01265	COG4191	Histidine kinase
GPY07_RS01265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY07_RS01270	COG0471	metal ion transport
GPY07_RS01280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY07_RS01295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY07_RS01300	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GPY07_RS01305	COG3768	UPF0283 membrane protein
GPY07_RS01310	COG3106	COG3106 Predicted ATPase
GPY07_RS01325	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY07_RS01330	COG0494	nUDIX hydrolase
GPY07_RS01335	COG0814	amino acid
GPY07_RS01340	COG1760	l-serine dehydratase
GPY07_RS01345	COG0720	synthase
GPY07_RS01355	COG0017	Asparaginyl-tRNA synthetase
GPY07_RS01360	COG0351	phosphomethylpyrimidine kinase
GPY07_RS01365	COG2770	Histidine kinase
GPY07_RS01365	COG3437	response regulator, receiver
GPY07_RS01375	COG1448	Aminotransferase
GPY07_RS01390	COG0840	transmembrane signaling receptor activity
GPY07_RS01395	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GPY07_RS01400	COG2943	transferase activity, transferring hexosyl groups
GPY07_RS01405	COG1609	Transcriptional regulator
GPY07_RS01410	COG3394	polysaccharide catabolic process
GPY07_RS01415	COG1486	melibiose metabolic process
GPY07_RS01420	COG1447	Phosphotransferase system cellobiose-specific component IIA
GPY07_RS01430	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPY07_RS01435	COG0726	polysaccharide deacetylase
GPY07_RS01440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY07_RS01445	COG1846	Transcriptional regulator
GPY07_RS01470	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPY07_RS01485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY07_RS01490	COG3108	Peptidase M15
GPY07_RS01495	COG2989	Protein conserved in bacteria
GPY07_RS01520	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY07_RS01530	COG2814	Major facilitator Superfamily
GPY07_RS01550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY07_RS01555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY07_RS01560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY07_RS01605	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GPY07_RS01610	COG4139	cobalamin transport
GPY07_RS01615	COG2988	succinylglutamate desuccinylase activity
GPY07_RS01630	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GPY07_RS01635	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GPY07_RS01640	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY07_RS01650	COG2925	Exonuclease
GPY07_RS01660	COG1346	cytolysis
GPY07_RS01665	COG0295	cytidine deaminase activity
GPY07_RS01685	COG0500	methyltransferase
GPY07_RS01700	COG0776	regulation of translation
GPY07_RS01705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY07_RS01705	COG0072	phenylalanine-tRNA ligase activity
GPY07_RS01710	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPY07_RS01720	COG0745	RESPONSE REGULATOR receiver
GPY07_RS01720	COG3706	GGDEF domain
GPY07_RS01750	COG0322	excinuclease ABC activity
GPY07_RS01755	COG2197	response regulator
GPY07_RS01760	COG0417	DNA replication proofreading
GPY07_RS01765	COG5001	Diguanylate cyclase
GPY07_RS01775	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPY07_RS01795	COG1228	amidohydrolase
GPY07_RS01800	COG0010	Belongs to the arginase family
GPY07_RS01805	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GPY07_RS01810	COG2986	histidine ammonia-lyase
GPY07_RS01830	COG0277	FAD linked oxidase domain protein
GPY07_RS01830	COG0247	lactate metabolic process
GPY07_RS01845	COG2885	chlorophyll binding
GPY07_RS01865	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GPY07_RS01875	COG0281	malic enzyme
GPY07_RS01885	COG2949	membrane
GPY07_RS01890	COG3706	GGDEF domain
GPY07_RS01895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPY07_RS01905	COG0492	ferredoxin-NADP+ reductase activity
GPY07_RS01910	COG4988	ABC transporter
GPY07_RS01915	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GPY07_RS01920	COG1187	pseudouridine synthase activity
GPY07_RS01925	COG0009	L-threonylcarbamoyladenylate synthase
GPY07_RS01930	COG0613	PHP domain protein
GPY07_RS01940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY07_RS01945	COG0512	Glutamine amidotransferase of anthranilate synthase
GPY07_RS01950	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPY07_RS01955	COG0135	phosphoribosylanthranilate isomerase activity
GPY07_RS01955	COG0134	indole-3-glycerol-phosphate synthase activity
GPY07_RS01960	COG0133	tryptophan synthase activity
GPY07_RS01965	COG0159	tryptophan synthase activity
GPY07_RS01975	COG1435	thymidine kinase activity
GPY07_RS01980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GPY07_RS01985	COG1801	Protein of unknown function DUF72
GPY07_RS01990	COG4106	trans-aconitate 2-methyltransferase activity
GPY07_RS01995	COG0500	methyltransferase
GPY07_RS02000	COG4067	protein conserved in archaea
GPY07_RS02000	COG0189	ligase activity
GPY07_RS02015	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPY07_RS02025	COG3852	Histidine kinase
GPY07_RS02040	COG3070	regulator of competence-specific genes
GPY07_RS02050	COG2431	L-lysine efflux transmembrane transporter activity
GPY07_RS02060	COG0076	glutamate decarboxylase activity
GPY07_RS02065	COG1737	Transcriptional regulator
GPY07_RS02075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY07_RS02085	COG0542	response to heat
GPY07_RS02090	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GPY07_RS02095	COG1278	Cold shock
GPY07_RS02105	COG1187	pseudouridine synthase activity
GPY07_RS02110	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GPY07_RS02110	COG0140	phosphoribosyl-ATP diphosphatase activity
GPY07_RS02115	COG0107	imidazoleglycerol-phosphate synthase activity
GPY07_RS02120	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPY07_RS02125	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPY07_RS02130	COG0131	Imidazoleglycerol-phosphate dehydratase
GPY07_RS02130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPY07_RS02135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPY07_RS02140	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPY07_RS02145	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GPY07_RS02150	COG1757	Na H antiporter
GPY07_RS02155	COG2916	Histone family protein nucleoid-structuring protein H-NS
GPY07_RS02160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY07_RS02165	COG0482	sulfurtransferase activity
GPY07_RS02170	COG2915	High frequency lysogenization protein hflD homolog
GPY07_RS02175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPY07_RS02185	COG2268	Band 7 protein
GPY07_RS02195	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GPY07_RS02210	COG0300	oxidoreductase activity
GPY07_RS02220	COG0501	Belongs to the peptidase M48B family
GPY07_RS02230	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GPY07_RS02235	COG2226	methyltransferase
GPY07_RS02240	COG0156	8-amino-7-oxononanoate synthase activity
GPY07_RS02245	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPY07_RS02250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GPY07_RS02255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPY07_RS02260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GPY07_RS02265	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GPY07_RS02275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY07_RS02280	COG2203	Gaf domain
GPY07_RS02280	COG2199	diguanylate cyclase activity
GPY07_RS02290	COG4120	Belongs to the binding-protein-dependent transport system permease family
GPY07_RS02300	COG4628	conserved protein (DUF2132)
GPY07_RS02305	COG3092	negative regulation of chromosome organization
GPY07_RS02310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPY07_RS02315	COG0280	phosphate acetyltransferase
GPY07_RS02315	COG0857	belongs to the CobB CobQ family
GPY07_RS02320	COG0435	Glutathione S-transferase
GPY07_RS02325	COG4608	Belongs to the ABC transporter superfamily
GPY07_RS02330	COG0444	Belongs to the ABC transporter superfamily
GPY07_RS02335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY07_RS02340	COG0601	transmembrane transport
GPY07_RS02360	COG2204	response regulator
GPY07_RS02365	COG3300	MHYT domain
GPY07_RS02365	COG5001	Diguanylate cyclase
GPY07_RS02370	COG4191	Histidine kinase
GPY07_RS02375	COG5002	protein histidine kinase activity
GPY07_RS02385	COG2201	protein-glutamate methylesterase activity
GPY07_RS02400	COG0009	L-threonylcarbamoyladenylate synthase
GPY07_RS02420	COG1881	PFAM PEBP family protein
GPY07_RS02445	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY07_RS02450	COG0640	Transcriptional regulator
GPY07_RS02460	COG3706	GGDEF domain
GPY07_RS02480	COG1946	Acyl-CoA thioesterase
GPY07_RS02485	COG1522	sequence-specific DNA binding
GPY07_RS02495	COG0616	signal peptide processing
GPY07_RS02500	COG1028	Short-chain dehydrogenase reductase Sdr
GPY07_RS02515	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPY07_RS02520	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPY07_RS02530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPY07_RS02535	COG2832	Protein of unknown function (DUF454)
GPY07_RS02545	COG0745	RESPONSE REGULATOR receiver
GPY07_RS02550	COG0583	DNA-binding transcription factor activity
GPY07_RS02555	COG0778	Nitroreductase
GPY07_RS02560	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPY07_RS02560	COG1024	Enoyl-CoA hydratase
GPY07_RS02565	COG0183	Belongs to the thiolase family
GPY07_RS02590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPY07_RS02595	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GPY07_RS02600	COG2982	Protein involved in outer membrane biogenesis
GPY07_RS02605	COG0572	uridine kinase
GPY07_RS02610	COG0489	protein tyrosine kinase activity
GPY07_RS02615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY07_RS02615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY07_RS02625	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GPY07_RS02635	COG4109	DRTGG domain
GPY07_RS02640	COG2199	diguanylate cyclase activity
GPY07_RS02645	COG0314	molybdopterin synthase activity
GPY07_RS02650	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPY07_RS02655	COG0315	cyclic pyranopterin monophosphate synthase activity
GPY07_RS02660	COG0521	Mo-molybdopterin cofactor biosynthetic process
GPY07_RS02665	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPY07_RS02670	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GPY07_RS02675	COG2198	Histidine kinase
GPY07_RS02680	COG2204	response regulator
GPY07_RS02685	COG0556	nucleotide-excision repair
GPY07_RS02695	COG4657	Part of a membrane complex involved in electron transport
GPY07_RS02700	COG2878	Part of a membrane complex involved in electron transport
GPY07_RS02705	COG4656	Part of a membrane complex involved in electron transport
GPY07_RS02710	COG4658	electron transport chain
GPY07_RS02715	COG4659	FMN binding
GPY07_RS02720	COG4660	Part of a membrane complex involved in electron transport
GPY07_RS02725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPY07_RS02730	COG0346	lactoylglutathione lyase activity
GPY07_RS02745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPY07_RS02750	COG2056	Na+-H+ antiporter family
GPY07_RS02755	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPY07_RS02760	COG1286	toxin biosynthetic process
GPY07_RS02765	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GPY07_RS02770	COG0285	dihydrofolate synthase activity
GPY07_RS02775	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPY07_RS02780	COG0101	tRNA pseudouridine synthase activity
GPY07_RS02790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY07_RS02795	COG2190	(PTS) system
GPY07_RS02795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY07_RS02795	COG1263	PTS System
GPY07_RS02800	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPY07_RS02805	COG1940	carbohydrate kinase activity
GPY07_RS02805	COG1846	Transcriptional regulator
GPY07_RS02810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPY07_RS02810	COG4651	solute:proton antiporter activity
GPY07_RS02815	COG0367	asparagine synthase
GPY07_RS02830	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GPY07_RS02835	COG0563	adenylate kinase activity
GPY07_RS02840	COG0326	Molecular chaperone. Has ATPase activity
GPY07_RS02845	COG3710	Transcriptional regulator
GPY07_RS02860	COG0622	Phosphoesterase
GPY07_RS02865	COG1090	epimerase
GPY07_RS02870	COG0300	oxidoreductase activity
GPY07_RS02880	COG3118	belongs to the thioredoxin family
GPY07_RS02885	COG0330	HflC and HflK could
GPY07_RS02890	COG1585	Membrane protein implicated in regulation of membrane protease activity
GPY07_RS02895	COG0789	Transcriptional regulator
GPY07_RS02910	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPY07_RS02915	COG3115	cell septum assembly
GPY07_RS02920	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GPY07_RS02925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPY07_RS02935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY07_RS02945	COG2190	(PTS) system
GPY07_RS02950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY07_RS02955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPY07_RS02960	COG1702	phosphate starvation-inducible protein PhoH
GPY07_RS02965	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPY07_RS02970	COG4535	Mg2 and Co2 transporter CorC
GPY07_RS02975	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GPY07_RS02980	COG2888	peptidyl-tyrosine sulfation
GPY07_RS02985	COG0495	leucyl-tRNA aminoacylation
GPY07_RS02990	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GPY07_RS02995	COG1466	dna polymerase III delta subunit
GPY07_RS03000	COG0799	negative regulation of ribosome biogenesis
GPY07_RS03005	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPY07_RS03010	COG0768	penicillin binding
GPY07_RS03015	COG0772	Belongs to the SEDS family
GPY07_RS03020	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPY07_RS03025	COG1686	Belongs to the peptidase S11 family
GPY07_RS03030	COG2921	Belongs to the UPF0250 family
GPY07_RS03035	COG0321	lipoyl(octanoyl) transferase activity
GPY07_RS03040	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GPY07_RS03050	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPY07_RS03075	COG1596	polysaccharide export
GPY07_RS03085	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPY07_RS03115	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GPY07_RS03125	COG0438	transferase activity, transferring glycosyl groups
GPY07_RS03135	COG1045	serine acetyltransferase
GPY07_RS03155	COG0110	maltose O-acetyltransferase activity
GPY07_RS03160	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GPY07_RS03165	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GPY07_RS03170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPY07_RS03205	COG0366	Alpha amylase catalytic
GPY07_RS03210	COG1263	PTS System
GPY07_RS03210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY07_RS03215	COG1609	Transcriptional regulator
GPY07_RS03220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPY07_RS03225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPY07_RS03230	COG2011	ABC-type metal ion transport system permease component
GPY07_RS03235	COG1464	Belongs to the NlpA lipoprotein family
GPY07_RS03240	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GPY07_RS03250	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPY07_RS03250	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPY07_RS03260	COG3706	GGDEF domain
GPY07_RS03270	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY07_RS03275	COG2363	Small membrane protein
GPY07_RS03280	COG0583	DNA-binding transcription factor activity
GPY07_RS03285	COG0301	tRNA thio-modification
GPY07_RS03285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY07_RS03295	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPY07_RS03300	COG1722	exodeoxyribonuclease VII activity
GPY07_RS03305	COG0142	geranyltranstransferase activity
GPY07_RS03310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPY07_RS03315	COG0564	pseudouridine synthase activity
GPY07_RS03320	COG3098	single-species biofilm formation
GPY07_RS03335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY07_RS03345	COG1671	Belongs to the UPF0178 family
GPY07_RS03350	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY07_RS03355	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GPY07_RS03360	COG0254	rRNA binding
GPY07_RS03365	COG1720	tRNA m6t6A37 methyltransferase activity
GPY07_RS03370	COG0442	prolyl-tRNA aminoacylation
GPY07_RS03390	COG1943	Transposase
GPY07_RS03395	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPY07_RS03395	COG0047	phosphoribosylformylglycinamidine synthase activity
GPY07_RS03405	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GPY07_RS03410	COG0590	tRNA wobble adenosine to inosine editing
GPY07_RS03415	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY07_RS03440	COG4968	Prepilin-type N-terminal cleavage methylation domain
GPY07_RS03450	COG0484	heat shock protein binding
GPY07_RS03455	COG0443	Heat shock 70 kDa protein
GPY07_RS03460	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPY07_RS03465	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPY07_RS03470	COG0497	DNA recombination
GPY07_RS03475	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY07_RS03480	COG2914	Belongs to the UPF0125 (RnfH) family
GPY07_RS03485	COG2867	negative regulation of translational initiation
GPY07_RS03490	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GPY07_RS03500	COG0582	viral genome integration into host DNA
GPY07_RS03510	COG0582	viral genome integration into host DNA
GPY07_RS03515	COG3064	Membrane
GPY07_RS03525	COG0739	heme binding
GPY07_RS03540	COG0840	transmembrane signaling receptor activity
GPY07_RS03545	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GPY07_RS03550	COG2207	Transcriptional regulator
GPY07_RS03560	COG1459	type II secretion system
GPY07_RS03565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY07_RS03600	COG2165	general secretion pathway protein
GPY07_RS03610	COG3710	Transcriptional regulator
GPY07_RS03615	COG0840	transmembrane signaling receptor activity
GPY07_RS03620	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GPY07_RS03640	COG1012	belongs to the aldehyde dehydrogenase family
GPY07_RS03705	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GPY07_RS03710	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GPY07_RS03715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY07_RS03725	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GPY07_RS03730	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
GPY07_RS03735	COG3051	citrate lyase alpha subunit
GPY07_RS03740	COG2301	Belongs to the HpcH HpaI aldolase family
GPY07_RS03745	COG3052	prosthetic group binding
GPY07_RS03750	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GPY07_RS03760	COG3630	sodium ion export across plasma membrane
GPY07_RS03765	COG5016	pyruvate
GPY07_RS03765	COG0511	ligase activity, forming carbon-carbon bonds
GPY07_RS03770	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPY07_RS03780	COG4565	transcriptional regulatory protein
GPY07_RS03795	COG0583	DNA-binding transcription factor activity
GPY07_RS03800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY07_RS03805	COG1115	amino acid carrier protein
GPY07_RS03810	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GPY07_RS03815	COG0583	DNA-binding transcription factor activity
GPY07_RS03825	COG1120	ATPase activity
GPY07_RS03835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY07_RS03840	COG4592	Periplasmic binding protein
GPY07_RS03850	COG1028	Short-chain dehydrogenase reductase Sdr
GPY07_RS03855	COG1169	isochorismate synthase
GPY07_RS03860	COG1021	2,3-dihydroxybenzoate-AMP ligase
GPY07_RS03865	COG1535	isochorismatase
GPY07_RS03865	COG3433	isochorismatase activity
GPY07_RS03870	COG1584	GPR1 FUN34 yaaH family protein
GPY07_RS03880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GPY07_RS03880	COG0519	Catalyzes the synthesis of GMP from XMP
GPY07_RS03885	COG0516	GMP reductase activity
GPY07_RS03885	COG0517	IMP dehydrogenase activity
GPY07_RS03890	COG1570	exodeoxyribonuclease VII activity
GPY07_RS03905	COG1160	GTP binding
GPY07_RS03910	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY07_RS03915	COG2976	Protein conserved in bacteria
GPY07_RS03920	COG0124	histidyl-tRNA synthetase
GPY07_RS03925	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GPY07_RS03935	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GPY07_RS03940	COG0105	UTP biosynthetic process
GPY07_RS03945	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPY07_RS03950	COG2975	iron-sulfur cluster assembly
GPY07_RS03955	COG0633	Ferredoxin
GPY07_RS03960	COG0443	Heat shock 70 kDa protein
GPY07_RS03965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPY07_RS03975	COG0822	iron-sulfur transferase activity
GPY07_RS03980	COG1104	cysteine desulfurase activity
GPY07_RS03985	COG1959	2 iron, 2 sulfur cluster binding
GPY07_RS03995	COG0483	inositol monophosphate 1-phosphatase activity
GPY07_RS04000	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY07_RS04005	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY07_RS04010	COG1862	Preprotein translocase
GPY07_RS04015	COG0343	queuine tRNA-ribosyltransferase activity
GPY07_RS04020	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPY07_RS04025	COG0517	IMP dehydrogenase activity
GPY07_RS04035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GPY07_RS04040	COG0583	DNA-binding transcription factor activity
GPY07_RS04045	COG0450	alkyl hydroperoxide reductase
GPY07_RS04050	COG3142	Participates in the control of copper homeostasis
GPY07_RS04065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY07_RS04070	COG0581	inorganic phosphate transmembrane transporter activity
GPY07_RS04080	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GPY07_RS04085	COG0248	Ppx GppA phosphatase
GPY07_RS04095	COG5002	protein histidine kinase activity
GPY07_RS04100	COG0745	RESPONSE REGULATOR receiver
GPY07_RS04105	COG2974	May be involved in recombination
GPY07_RS04115	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPY07_RS04155	COG0542	response to heat
GPY07_RS04165	COG0564	pseudouridine synthase activity
GPY07_RS04170	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY07_RS04175	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY07_RS04180	COG0077	Prephenate dehydratase
GPY07_RS04180	COG1605	Chorismate mutase
GPY07_RS04185	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY07_RS04190	COG5001	Diguanylate cyclase
GPY07_RS04195	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GPY07_RS04200	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GPY07_RS04210	COG0488	(ABC) transporter
GPY07_RS04220	COG1605	Chorismate mutase
GPY07_RS04220	COG0287	Prephenate dehydrogenase
GPY07_RS04225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY07_RS04230	COG3275	phosphorelay sensor kinase activity
GPY07_RS04235	COG3279	Response regulator of the LytR AlgR family
GPY07_RS04240	COG1472	Belongs to the glycosyl hydrolase 3 family
GPY07_RS04245	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GPY07_RS04250	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPY07_RS04265	COG1966	Carbon starvation protein
GPY07_RS04270	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GPY07_RS04275	COG1047	Peptidyl-prolyl cis-trans
GPY07_RS04280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPY07_RS04285	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPY07_RS04290	COG0196	riboflavin kinase activity
GPY07_RS04295	COG0728	peptidoglycan biosynthetic process
GPY07_RS04300	COG0268	Binds directly to 16S ribosomal RNA
GPY07_RS04305	COG0640	Transcriptional regulator
GPY07_RS04310	COG0583	DNA-binding transcription factor activity
GPY07_RS04315	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPY07_RS04320	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPY07_RS04325	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPY07_RS04330	COG0730	response to heat
GPY07_RS04335	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GPY07_RS04340	COG0494	nUDIX hydrolase
GPY07_RS04345	COG3066	DNA modification
GPY07_RS04350	COG0667	Aldo Keto reductase
GPY07_RS04365	COG2204	response regulator
GPY07_RS04370	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GPY07_RS04385	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GPY07_RS04390	COG0513	Belongs to the DEAD box helicase family
GPY07_RS04395	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GPY07_RS04455	COG4999	Histidine kinase
GPY07_RS04455	COG3850	Histidine kinase
GPY07_RS04455	COG2205	protein histidine kinase activity
GPY07_RS04455	COG3437	response regulator, receiver
GPY07_RS04460	COG3706	GGDEF domain
GPY07_RS04460	COG0745	RESPONSE REGULATOR receiver
GPY07_RS04480	COG2003	Belongs to the UPF0758 family
GPY07_RS04505	COG0714	Associated with various cellular activities
GPY07_RS04520	COG0629	single-stranded DNA binding
GPY07_RS04535	COG2356	endonuclease I
GPY07_RS04570	COG0681	Belongs to the peptidase S26 family
GPY07_RS04585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY07_RS04630	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
GPY07_RS04660	COG1196	nuclear chromosome segregation
GPY07_RS04725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPY07_RS04790	COG0717	Belongs to the dCTP deaminase family
GPY07_RS04875	COG3153	acetyltransferase
GPY07_RS04910	COG4785	May be involved in cell division
GPY07_RS04915	COG1185	polyribonucleotide nucleotidyltransferase activity
GPY07_RS04920	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPY07_RS04925	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPY07_RS04930	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPY07_RS04935	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPY07_RS04940	COG0195	Participates in both transcription termination and antitermination
GPY07_RS04945	COG0779	Required for maturation of 30S ribosomal subunits
GPY07_RS04960	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY07_RS04965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY07_RS04970	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPY07_RS04975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPY07_RS04980	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GPY07_RS04985	COG1534	Rna-binding protein
GPY07_RS04990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY07_RS04995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPY07_RS05000	COG2027	D-alanyl-D-alanine carboxypeptidase
GPY07_RS05005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPY07_RS05010	COG0739	heme binding
GPY07_RS05025	COG0316	Belongs to the HesB IscA family
GPY07_RS05030	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GPY07_RS05040	COG0628	permease
GPY07_RS05045	COG2813	Specifically methylates the guanine in position
GPY07_RS05055	COG0747	negative chemotaxis
GPY07_RS05060	COG0601	transmembrane transport
GPY07_RS05065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY07_RS05070	COG0444	Belongs to the ABC transporter superfamily
GPY07_RS05075	COG4608	Belongs to the ABC transporter superfamily
GPY07_RS05085	COG2971	BadF BadG BcrA BcrD
GPY07_RS05105	COG3842	ATPase activity
GPY07_RS05115	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY07_RS05120	COG0004	ammonium transporteR
GPY07_RS05125	COG0347	Belongs to the P(II) protein family
GPY07_RS05130	COG3112	Uncharacterised protein family (UPF0231)
GPY07_RS05135	COG1049	propionate catabolic process, 2-methylcitrate cycle
GPY07_RS05140	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPY07_RS05145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPY07_RS05150	COG1643	Atp-dependent helicase
GPY07_RS05160	COG1489	DNA binding
GPY07_RS05165	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY07_RS05170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY07_RS05180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY07_RS05185	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GPY07_RS05190	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GPY07_RS05195	COG0842	Transport permease protein
GPY07_RS05200	COG1131	(ABC) transporter
GPY07_RS05205	COG0659	secondary active sulfate transmembrane transporter activity
GPY07_RS05210	COG0288	reversible hydration of carbon dioxide
GPY07_RS05225	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPY07_RS05230	COG3107	peptidoglycan biosynthetic process
GPY07_RS05235	COG0792	nuclease activity
GPY07_RS05240	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPY07_RS05245	COG2823	Periplasmic or secreted lipoprotein
GPY07_RS05250	COG2969	positive regulation of protein catabolic process
GPY07_RS05255	COG0625	glutathione transferase activity
GPY07_RS05260	COG2857	Cytochrome c1
GPY07_RS05265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GPY07_RS05270	COG0723	plastoquinol--plastocyanin reductase activity
GPY07_RS05275	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GPY07_RS05280	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPY07_RS05285	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GPY07_RS05295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPY07_RS05300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPY07_RS05305	COG0335	large ribosomal subunit rRNA binding
GPY07_RS05310	COG0336	Belongs to the RNA methyltransferase TrmD family
GPY07_RS05315	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPY07_RS05320	COG0228	four-way junction DNA binding
GPY07_RS05325	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPY07_RS05330	COG4137	Cytochrome C assembly protein
GPY07_RS05335	COG4536	flavin adenine dinucleotide binding
GPY07_RS05340	COG1854	S-ribosylhomocysteine lyase activity
GPY07_RS05345	COG2918	glutathione biosynthetic process
GPY07_RS05350	COG0612	Peptidase, M16
GPY07_RS05355	COG1238	metal cluster binding
GPY07_RS05365	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPY07_RS05370	COG5016	pyruvate
GPY07_RS05370	COG0511	ligase activity, forming carbon-carbon bonds
GPY07_RS05375	COG3630	sodium ion export across plasma membrane
GPY07_RS05420	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GPY07_RS05425	COG0527	aspartate kinase activity
GPY07_RS05430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPY07_RS05435	COG2137	regulation of response to DNA damage stimulus
GPY07_RS05440	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPY07_RS05450	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GPY07_RS05455	COG4208	sulfate ABC transporter
GPY07_RS05475	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPY07_RS05480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPY07_RS05485	COG4942	peptidase
GPY07_RS05485	COG1388	LysM domain
GPY07_RS05490	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GPY07_RS05495	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GPY07_RS05500	COG0585	pseudouridine synthase activity
GPY07_RS05505	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GPY07_RS05510	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPY07_RS05515	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GPY07_RS05520	COG1968	undecaprenyl-diphosphatase activity
GPY07_RS05525	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY07_RS05530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPY07_RS05535	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GPY07_RS05545	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPY07_RS05550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GPY07_RS05555	COG1610	YqeY-like protein
GPY07_RS05560	COG0358	DNA primase activity
GPY07_RS05565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPY07_RS05575	COG0582	viral genome integration into host DNA
GPY07_RS05580	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY07_RS05585	COG0840	transmembrane signaling receptor activity
GPY07_RS05590	COG2207	Transcriptional regulator
GPY07_RS05595	COG0840	transmembrane signaling receptor activity
GPY07_RS05605	COG2003	Belongs to the UPF0758 family
GPY07_RS05640	COG0739	heme binding
GPY07_RS05665	COG0328	RNA-DNA hybrid ribonuclease activity
GPY07_RS05715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPY07_RS05720	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GPY07_RS05725	COG1349	DNA-binding transcription factor activity
GPY07_RS05730	COG0469	pyruvate kinase activity
GPY07_RS05740	COG0583	DNA-binding transcription factor activity
GPY07_RS05745	COG1279	arginine transmembrane transporter activity
GPY07_RS05750	COG0668	transmembrane transport
GPY07_RS05760	COG0191	fructose-bisphosphate aldolase activity
GPY07_RS05765	COG0126	phosphoglycerate kinase activity
GPY07_RS05770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY07_RS05775	COG4771	TonB-dependent receptor
GPY07_RS05780	COG0583	DNA-binding transcription factor activity
GPY07_RS05785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPY07_RS05790	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPY07_RS05795	COG3091	SprT-like family
GPY07_RS05800	COG2356	endonuclease I
GPY07_RS05805	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GPY07_RS05810	COG0189	ligase activity
GPY07_RS05815	COG1678	Uncharacterized ACR, COG1678
GPY07_RS05820	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPY07_RS05825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPY07_RS05845	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPY07_RS05850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPY07_RS05855	COG0762	integral membrane protein
GPY07_RS05860	COG1872	DUF167
GPY07_RS05870	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPY07_RS05875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY07_RS05880	COG2066	Belongs to the glutaminase family
GPY07_RS05885	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GPY07_RS05890	COG1194	a g-specific adenine glycosylase
GPY07_RS05895	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GPY07_RS05900	COG0741	lytic transglycosylase activity
GPY07_RS05955	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPY07_RS05960	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GPY07_RS05965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY07_RS05970	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GPY07_RS05975	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GPY07_RS05980	COG2967	ApaG domain
GPY07_RS05985	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GPY07_RS05995	COG3610	response to peptide
GPY07_RS06000	COG2966	Psort location CytoplasmicMembrane, score
GPY07_RS06005	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPY07_RS06010	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GPY07_RS06015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GPY07_RS06020	COG0142	geranyltranstransferase activity
GPY07_RS06030	COG0039	L-malate dehydrogenase activity
GPY07_RS06035	COG1438	arginine binding
GPY07_RS06050	COG0589	response to stress
GPY07_RS06070	COG2235	arginine
GPY07_RS06075	COG0312	modulator of DNA gyrase
GPY07_RS06080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPY07_RS06085	COG3164	Protein of unknown function
GPY07_RS06090	COG1530	ribonuclease E activity
GPY07_RS06095	COG0424	maF-like protein
GPY07_RS06100	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GPY07_RS06105	COG1792	Involved in formation and maintenance of cell shape
GPY07_RS06110	COG1077	Cell shape determining protein MreB Mrl
GPY07_RS06155	COG1459	type II secretion system
GPY07_RS06160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY07_RS06170	COG3267	Type II secretory pathway component ExeA
GPY07_RS06170	COG3409	Peptidoglycan-binding domain 1 protein
GPY07_RS06195	COG2200	EAL domain
GPY07_RS06195	COG2199	diguanylate cyclase activity
GPY07_RS06200	COG0629	single-stranded DNA binding
GPY07_RS06215	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPY07_RS06225	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPY07_RS06230	COG0527	aspartate kinase activity
GPY07_RS06235	COG1410	methionine synthase
GPY07_RS06235	COG0646	methionine synthase
GPY07_RS06305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPY07_RS06315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPY07_RS06320	COG0408	coproporphyrinogen oxidase activity
GPY07_RS06325	COG0009	L-threonylcarbamoyladenylate synthase
GPY07_RS06330	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPY07_RS06335	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPY07_RS06340	COG0551	DNA topoisomerase type I activity
GPY07_RS06345	COG2922	Belongs to the Smg family
GPY07_RS06350	COG0758	DNA mediated transformation
GPY07_RS06355	COG1652	LysM domain
GPY07_RS06360	COG0242	peptide deformylase activity
GPY07_RS06365	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPY07_RS06370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPY07_RS06370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPY07_RS06375	COG0569	domain protein
GPY07_RS06380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY07_RS06390	COG1272	protein, Hemolysin III
GPY07_RS06395	COG4326	sporulation control protein
GPY07_RS06405	COG3084	Protein conserved in bacteria
GPY07_RS06415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPY07_RS06420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY07_RS06425	COG0204	Acyl-transferase
GPY07_RS06430	COG0606	chelatase, subunit chli
GPY07_RS06445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPY07_RS06450	COG0129	dihydroxy-acid dehydratase activity
GPY07_RS06460	COG0604	alcohol dehydrogenase
GPY07_RS06470	COG0425	Belongs to the sulfur carrier protein TusA family
GPY07_RS06480	COG2119	membrane
GPY07_RS06485	COG0752	glycyl-tRNA synthetase alpha subunit
GPY07_RS06490	COG0751	glycine-tRNA ligase activity
GPY07_RS06495	COG3977	Valine--pyruvate aminotransferase
GPY07_RS06500	COG0071	Belongs to the small heat shock protein (HSP20) family
GPY07_RS06515	COG0187	DNA topoisomerase II activity
GPY07_RS06520	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPY07_RS06525	COG0592	DNA-directed DNA polymerase activity
GPY07_RS06530	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPY07_RS06545	COG1126	abc transporter atp-binding protein
GPY07_RS06550	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GPY07_RS06555	COG0594	ribonuclease P activity
GPY07_RS06560	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GPY07_RS06565	COG0706	membrane insertase activity
GPY07_RS06570	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPY07_RS06575	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY07_RS06585	COG0445	tRNA wobble uridine modification
GPY07_RS06590	COG0357	Ribosomal RNA small subunit methyltransferase G
GPY07_RS06595	COG1192	Involved in chromosome partitioning
GPY07_RS06600	COG1475	DNA binding
GPY07_RS06605	COG3312	ion transport
GPY07_RS06610	COG0356	it plays a direct role in the translocation of protons across the membrane
GPY07_RS06620	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPY07_RS06625	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPY07_RS06630	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPY07_RS06635	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPY07_RS06640	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPY07_RS06645	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GPY07_RS06650	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPY07_RS06655	COG2814	Major facilitator Superfamily
GPY07_RS06660	COG0583	DNA-binding transcription factor activity
GPY07_RS06665	COG0183	Belongs to the thiolase family
GPY07_RS06670	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPY07_RS06670	COG1024	Enoyl-CoA hydratase
GPY07_RS06675	COG1739	Uncharacterized protein family UPF0029
GPY07_RS06680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY07_RS06685	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GPY07_RS06730	COG0583	DNA-binding transcription factor activity
GPY07_RS06735	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPY07_RS06740	COG2960	long-chain fatty acid transporting porin activity
GPY07_RS06745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY07_RS06750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY07_RS06755	COG1309	transcriptional regulator
GPY07_RS06810	COG0747	negative chemotaxis
GPY07_RS06820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY07_RS06830	COG2131	deaminase
GPY07_RS06895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY07_RS06900	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GPY07_RS06910	COG0210	DNA helicase
GPY07_RS06915	COG1280	lysine exporter protein (LysE YggA)
GPY07_RS06935	COG0514	ATP-dependent DNA helicase (RecQ)
GPY07_RS06950	COG1132	(ABC) transporter
GPY07_RS06955	COG4774	siderophore transport
GPY07_RS06960	COG1120	ATPase activity
GPY07_RS06985	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPY07_RS06990	COG1263	PTS System
GPY07_RS06990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY07_RS07000	COG1561	YicC-like family, N-terminal region
GPY07_RS07005	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GPY07_RS07010	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPY07_RS07015	COG1560	Kdo2-lipid A biosynthetic process
GPY07_RS07020	COG1560	Kdo2-lipid A biosynthetic process
GPY07_RS07025	COG1309	transcriptional regulator
GPY07_RS07035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPY07_RS07050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GPY07_RS07055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GPY07_RS07065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GPY07_RS07070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPY07_RS07075	COG0859	PFAM glycosyl transferase family 9
GPY07_RS07080	COG0463	Glycosyl transferase, family 2
GPY07_RS07085	COG0859	PFAM glycosyl transferase family 9
GPY07_RS07090	COG3642	lipopolysaccharide core region biosynthetic process
GPY07_RS07120	COG1519	Transferase
GPY07_RS07155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY07_RS07165	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY07_RS07200	COG5433	transposase activity
GPY07_RS07220	COG1051	belongs to the nudix hydrolase family
GPY07_RS07245	COG1215	transferase activity, transferring glycosyl groups
GPY07_RS07250	COG1216	Glycosyl transferase, family 2
GPY07_RS07260	COG0367	asparagine synthase
GPY07_RS07265	COG0438	transferase activity, transferring glycosyl groups
GPY07_RS07270	COG0662	Cupin 2, conserved barrel domain protein
GPY07_RS07270	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GPY07_RS07285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPY07_RS07305	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GPY07_RS07320	COG0668	transmembrane transport
GPY07_RS07330	COG3068	Protein conserved in bacteria
GPY07_RS07335	COG1253	flavin adenine dinucleotide binding
GPY07_RS07340	COG0776	regulation of translation
GPY07_RS07350	COG0151	Belongs to the GarS family
GPY07_RS07355	COG0138	bifunctional purine biosynthesis protein purh
GPY07_RS07365	COG0789	Transcriptional regulator
GPY07_RS07370	COG3710	Transcriptional regulator
GPY07_RS07375	COG0531	amino acid
GPY07_RS07380	COG1982	Orn Lys Arg decarboxylase major
GPY07_RS07385	COG0840	transmembrane signaling receptor activity
GPY07_RS07400	COG0800	Aldolase
GPY07_RS07410	COG3265	gluconokinase activity
GPY07_RS07415	COG0129	dihydroxy-acid dehydratase activity
GPY07_RS07420	COG1609	Transcriptional regulator
GPY07_RS07425	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GPY07_RS07430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY07_RS07435	COG2264	protein methyltransferase activity
GPY07_RS07440	COG0439	Biotin carboxylase
GPY07_RS07445	COG0511	ligase activity, forming carbon-carbon bonds
GPY07_RS07450	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GPY07_RS07455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY07_RS07475	COG2814	Major facilitator Superfamily
GPY07_RS07480	COG2205	protein histidine kinase activity
GPY07_RS07480	COG0784	Response regulator, receiver
GPY07_RS07485	COG0248	Ppx GppA phosphatase
GPY07_RS07490	COG0513	Belongs to the DEAD box helicase family
GPY07_RS07495	COG3118	belongs to the thioredoxin family
GPY07_RS07500	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPY07_RS07510	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GPY07_RS07555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPY07_RS07565	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GPY07_RS07575	COG1072	(Pantothenic acid kinase))
GPY07_RS07600	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPY07_RS07605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY07_RS07610	COG0250	Participates in transcription elongation, termination and antitermination
GPY07_RS07615	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPY07_RS07620	COG0081	regulation of translation
GPY07_RS07625	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPY07_RS07630	COG0222	ribosome binding
GPY07_RS07635	COG0085	RNA polymerase activity
GPY07_RS07640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPY07_RS07645	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GPY07_RS07650	COG2816	NAD+ diphosphatase activity
GPY07_RS07655	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GPY07_RS07670	COG4942	peptidase
GPY07_RS07675	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPY07_RS07685	COG0490	domain, Protein
GPY07_RS07685	COG0471	metal ion transport
GPY07_RS07690	COG0688	phosphatidylethanolamine metabolic process
GPY07_RS07695	COG1162	GTPase activity
GPY07_RS07700	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GPY07_RS07745	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPY07_RS07750	COG0802	atpase or kinase
GPY07_RS07760	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPY07_RS07765	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPY07_RS07770	COG1923	regulation of RNA biosynthetic process
GPY07_RS07775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPY07_RS07780	COG0330	HflC and HflK could
GPY07_RS07785	COG0330	HflC and HflK could
GPY07_RS07790	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GPY07_RS07795	COG2900	Belongs to the SlyX family
GPY07_RS07805	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY07_RS07810	COG2964	Protein conserved in bacteria
GPY07_RS07815	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GPY07_RS07820	COG2923	Belongs to the DsrF TusC family
GPY07_RS07830	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GPY07_RS07835	COG0049	tRNA binding
GPY07_RS07840	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPY07_RS07845	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPY07_RS07850	COG2906	2 iron, 2 sulfur cluster binding
GPY07_RS07860	COG0360	Binds together with S18 to 16S ribosomal RNA
GPY07_RS07865	COG2965	DNA replication, synthesis of RNA primer
GPY07_RS07870	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GPY07_RS07875	COG0359	binds to the 23S rRNA
GPY07_RS07885	COG0305	Participates in initiation and elongation during chromosome replication
GPY07_RS07890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY07_RS07895	COG0432	Pfam Uncharacterised protein family UPF0047
GPY07_RS07900	COG0166	Belongs to the GPI family
GPY07_RS07915	COG0735	belongs to the Fur family
GPY07_RS07920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY07_RS07945	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY07_RS07950	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPY07_RS07955	COG0175	sulfate reduction
GPY07_RS07995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPY07_RS08000	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GPY07_RS08010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY07_RS08015	COG2104	thiamine diphosphate biosynthetic process
GPY07_RS08020	COG2022	thiamine diphosphate biosynthetic process
GPY07_RS08025	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPY07_RS08030	COG0006	proline dipeptidase activity
GPY07_RS08030	COG0006	proline dipeptidase activity
GPY07_RS08050	COG1522	sequence-specific DNA binding
GPY07_RS08055	COG5001	Diguanylate cyclase
GPY07_RS08055	COG5002	protein histidine kinase activity
GPY07_RS08060	COG0742	ribosomal rna small subunit methyltransferase
GPY07_RS08070	COG0697	spore germination
GPY07_RS08075	COG0589	response to stress
GPY07_RS08085	COG1528	Iron-storage protein
GPY07_RS08095	COG2081	HI0933 family
GPY07_RS08105	COG1322	Protein conserved in bacteria
GPY07_RS08110	COG2226	methyltransferase
GPY07_RS08120	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GPY07_RS08125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPY07_RS08130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPY07_RS08135	COG0805	protein transport
GPY07_RS08140	COG1858	cytochrome C peroxidase
GPY07_RS08145	COG0534	Mate efflux family protein
GPY07_RS08155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPY07_RS08160	COG2937	Belongs to the GPAT DAPAT family
GPY07_RS08165	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GPY07_RS08170	COG3161	chorismate lyase activity
GPY07_RS08180	COG1580	Controls the rotational direction of flagella during chemotaxis
GPY07_RS08185	COG0840	transmembrane signaling receptor activity
GPY07_RS08195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY07_RS08200	COG0084	hydrolase, TatD family'
GPY07_RS08215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY07_RS08215	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY07_RS08220	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GPY07_RS08235	COG3078	GTPase activator activity
GPY07_RS08245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY07_RS08250	COG3071	HemY protein
GPY07_RS08255	COG2959	enzyme of heme biosynthesis
GPY07_RS08260	COG1587	Uroporphyrinogen-III synthase
GPY07_RS08265	COG0181	hydroxymethylbilane synthase activity
GPY07_RS08275	COG3072	Adenylate cyclase
GPY07_RS08280	COG1965	Belongs to the frataxin family
GPY07_RS08290	COG0019	diaminopimelate decarboxylase activity
GPY07_RS08295	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPY07_RS08305	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GPY07_RS08310	COG1011	Hydrolase
GPY07_RS08315	COG3287	FIST C domain
GPY07_RS08315	COG2199	diguanylate cyclase activity
GPY07_RS08315	COG2200	EAL domain
GPY07_RS08330	COG0561	phosphatase activity
GPY07_RS08335	COG2267	carboxylic ester hydrolase activity
GPY07_RS08340	COG1280	lysine exporter protein (LysE YggA)
GPY07_RS08345	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY07_RS08350	COG0783	Belongs to the Dps family
GPY07_RS08380	COG0742	ribosomal rna small subunit methyltransferase
GPY07_RS08385	COG0552	protein localization to endoplasmic reticulum
GPY07_RS08390	COG2884	Cell division ATP-binding protein ftsE
GPY07_RS08395	COG2177	Part of the ABC transporter FtsEX involved in
GPY07_RS08400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPY07_RS08405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY07_RS08420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY07_RS08425	COG4206	TonB-dependent receptor
GPY07_RS08430	COG1404	Belongs to the peptidase S8 family
GPY07_RS08435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GPY07_RS08505	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPY07_RS08510	COG3300	MHYT domain
GPY07_RS08510	COG5001	Diguanylate cyclase
GPY07_RS08520	COG3852	Histidine kinase
GPY07_RS08530	COG0174	glutamine synthetase
GPY07_RS08545	COG1660	Displays ATPase and GTPase activities
GPY07_RS08555	COG1490	D-aminoacyl-tRNA deacylase activity
GPY07_RS08560	COG0456	acetyltransferase
GPY07_RS08570	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GPY07_RS08575	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPY07_RS08580	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GPY07_RS08585	COG3031	protein transport across the cell outer membrane
GPY07_RS08595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY07_RS08600	COG1459	type II secretion system
GPY07_RS08605	COG2165	general secretion pathway protein
GPY07_RS08610	COG2165	general secretion pathway protein
GPY07_RS08615	COG2165	general secretion pathway protein
GPY07_RS08620	COG4795	General secretion pathway protein
GPY07_RS08625	COG3156	type II secretion system protein K
GPY07_RS08630	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPY07_RS08635	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPY07_RS08645	COG1218	3'(2'),5'-bisphosphate nucleotidase
GPY07_RS08650	COG0494	nUDIX hydrolase
GPY07_RS08655	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GPY07_RS08655	COG0316	Belongs to the HesB IscA family
GPY07_RS08660	COG1040	competence protein
GPY07_RS08665	COG0596	Alpha beta hydrolase
GPY07_RS08675	COG2183	response to ionizing radiation
GPY07_RS08680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY07_RS08685	COG0745	RESPONSE REGULATOR receiver
GPY07_RS08695	COG2233	PERMEase
GPY07_RS08705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY07_RS08710	COG1758	RNA polymerase activity
GPY07_RS08715	COG0194	GDP metabolic process
GPY07_RS08720	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPY07_RS08725	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY07_RS08735	COG3263	regulation of cellular component size
GPY07_RS08745	COG4232	protein-disulfide reductase activity
GPY07_RS08755	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPY07_RS08760	COG1027	Aspartate ammonia-lyase
GPY07_RS08765	COG3706	GGDEF domain
GPY07_RS08770	COG3030	protein affecting phage T7 exclusion by the F plasmid
GPY07_RS08775	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GPY07_RS08785	COG2205	protein histidine kinase activity
GPY07_RS08790	COG0745	RESPONSE REGULATOR receiver
GPY07_RS08800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPY07_RS08805	COG0205	6-phosphofructokinase activity
GPY07_RS08810	COG1494	fructose-1,6-bisphosphatase
GPY07_RS08815	COG3074	FtsZ-dependent cytokinesis
GPY07_RS08820	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPY07_RS08825	COG0460	homoserine dehydrogenase
GPY07_RS08825	COG0527	aspartate kinase activity
GPY07_RS08830	COG0626	cystathionine gamma-synthase activity
GPY07_RS08835	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
GPY07_RS08840	COG0281	malic enzyme
GPY07_RS08845	COG0254	rRNA binding
GPY07_RS08850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPY07_RS08855	COG1609	Transcriptional regulator
GPY07_RS08860	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPY07_RS08865	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GPY07_RS08870	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GPY07_RS08875	COG1575	Belongs to the MenA family. Type 1 subfamily
GPY07_RS08880	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPY07_RS08890	COG0149	triose-phosphate isomerase activity
GPY07_RS08915	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPY07_RS08920	COG0459	protein refolding
GPY07_RS08930	COG1509	lysine 2,3-aminomutase activity
GPY07_RS08935	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPY07_RS08940	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPY07_RS08945	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPY07_RS08950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPY07_RS08955	COG1053	succinate dehydrogenase
GPY07_RS08960	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GPY07_RS08965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY07_RS08970	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GPY07_RS08975	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GPY07_RS08980	COG1045	serine acetyltransferase
GPY07_RS08990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GPY07_RS08995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY07_RS09000	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPY07_RS09005	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPY07_RS09010	COG0137	argininosuccinate synthase activity
GPY07_RS09015	COG0165	Argininosuccinate lyase
GPY07_RS09025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY07_RS09030	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY07_RS09030	COG0678	peroxiredoxin activity
GPY07_RS09040	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GPY07_RS09070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GPY07_RS09075	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPY07_RS09085	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GPY07_RS09090	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPY07_RS09095	COG0546	phosphoglycolate phosphatase activity
GPY07_RS09100	COG0180	Tryptophanyl-tRNA synthetase
GPY07_RS09115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPY07_RS09125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPY07_RS09135	COG1012	belongs to the aldehyde dehydrogenase family
GPY07_RS09145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY07_RS09150	COG3954	Phosphoribulokinase
GPY07_RS09160	COG0429	hydrolase of the alpha beta-hydrolase fold
GPY07_RS09170	COG0488	(ABC) transporter
GPY07_RS09175	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPY07_RS09190	COG1047	Peptidyl-prolyl cis-trans
GPY07_RS09200	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPY07_RS09205	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GPY07_RS09210	COG3083	sulfuric ester hydrolase activity
GPY07_RS09220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY07_RS09225	COG0051	transcription antitermination factor activity, RNA binding
GPY07_RS09230	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPY07_RS09235	COG0088	Forms part of the polypeptide exit tunnel
GPY07_RS09240	COG0089	rRNA binding
GPY07_RS09245	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPY07_RS09250	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPY07_RS09255	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPY07_RS09260	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPY07_RS09265	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPY07_RS09270	COG0255	Belongs to the universal ribosomal protein uL29 family
GPY07_RS09275	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPY07_RS09280	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPY07_RS09285	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPY07_RS09290	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPY07_RS09295	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPY07_RS09300	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPY07_RS09305	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPY07_RS09310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPY07_RS09315	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GPY07_RS09320	COG1841	ribosomal large subunit assembly
GPY07_RS09325	COG0200	Binds to the 23S rRNA
GPY07_RS09330	COG0201	protein transport
GPY07_RS09340	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPY07_RS09345	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPY07_RS09350	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPY07_RS09355	COG0202	RNA polymerase activity
GPY07_RS09360	COG0203	ribosomal protein L17
GPY07_RS09370	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY07_RS09375	COG3061	Opacity-associated protein A
GPY07_RS09375	COG3266	domain, Protein
GPY07_RS09380	COG0697	spore germination
GPY07_RS09385	COG2153	protein acetylation
GPY07_RS09390	COG0513	Belongs to the DEAD box helicase family
GPY07_RS09400	COG0737	Belongs to the 5'-nucleotidase family
GPY07_RS09405	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPY07_RS09405	COG1648	precorrin-2 dehydrogenase activity
GPY07_RS09410	COG0175	sulfate reduction
GPY07_RS09415	COG2895	sulfate adenylyltransferase (ATP) activity
GPY07_RS09420	COG0529	Catalyzes the synthesis of activated sulfate
GPY07_RS09440	COG1136	(ABC) transporter
GPY07_RS09455	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GPY07_RS09460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY07_RS09465	COG0729	surface antigen
GPY07_RS09475	COG2105	PFAM AIG2 family protein
GPY07_RS09480	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GPY07_RS09485	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GPY07_RS09490	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPY07_RS09495	COG0163	prenyltransferase activity
GPY07_RS09500	COG4143	(ABC) transporter
GPY07_RS09505	COG1178	ABC-type Fe3 transport system permease component
GPY07_RS09510	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GPY07_RS09515	COG3028	Belongs to the UPF0307 family
GPY07_RS09520	COG0312	modulator of DNA gyrase
GPY07_RS09525	COG2239	Acts as a magnesium transporter
GPY07_RS09530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY07_RS09535	COG1660	Displays ATPase and GTPase activities
GPY07_RS09540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY07_RS09545	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY07_RS09555	COG1137	ATPase activity
GPY07_RS09560	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GPY07_RS09575	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GPY07_RS09575	COG0517	IMP dehydrogenase activity
GPY07_RS09585	COG1127	ABC transporter
GPY07_RS09590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GPY07_RS09595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPY07_RS09600	COG2854	intermembrane phospholipid transfer
GPY07_RS09610	COG5007	Belongs to the BolA IbaG family
GPY07_RS09615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPY07_RS09620	COG0204	Acyl-transferase
GPY07_RS09625	COG0251	oxidation-reduction process
GPY07_RS09630	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GPY07_RS09635	COG0540	Belongs to the ATCase OTCase family
GPY07_RS09640	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPY07_RS09645	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GPY07_RS09650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GPY07_RS09655	COG0564	pseudouridine synthase activity
GPY07_RS09660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY07_RS09665	COG0525	valine-tRNA ligase activity
GPY07_RS09670	COG2927	DNA polymerase III (CHI subunit)
GPY07_RS09675	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPY07_RS09680	COG0795	lipopolysaccharide-transporting ATPase activity
GPY07_RS09685	COG0795	lipopolysaccharide-transporting ATPase activity
GPY07_RS09700	COG3437	response regulator, receiver
GPY07_RS09745	COG0066	3-isopropylmalate dehydratase activity
GPY07_RS09750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPY07_RS09755	COG0473	3-isopropylmalate dehydrogenase activity
GPY07_RS09760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPY07_RS09780	COG0583	DNA-binding transcription factor activity
GPY07_RS09785	COG1022	Amp-dependent synthetase and ligase
GPY07_RS09790	COG0028	Belongs to the TPP enzyme family
GPY07_RS09795	COG0440	acetolactate synthase activity
GPY07_RS09800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY07_RS09805	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GPY07_RS09810	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPY07_RS09820	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPY07_RS09830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY07_RS09835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY07_RS09845	COG0354	folic acid binding
GPY07_RS09850	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GPY07_RS09860	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GPY07_RS09865	COG1595	DNA-templated transcription, initiation
GPY07_RS09875	COG3026	antisigma factor binding
GPY07_RS09880	COG3086	response to oxidative stress
GPY07_RS09885	COG0481	GTPase activity
GPY07_RS09890	COG0681	Belongs to the peptidase S26 family
GPY07_RS09895	COG0571	ribonuclease III activity
GPY07_RS09900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPY07_RS09905	COG1381	Involved in DNA repair and RecF pathway recombination
GPY07_RS09910	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GPY07_RS09915	COG0736	holo-[acyl-carrier-protein] synthase activity
GPY07_RS09930	COG5001	Diguanylate cyclase
GPY07_RS09940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY07_RS09945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY07_RS09950	COG3956	TIGRFAM MazG family protein
GPY07_RS09955	COG0504	CTP synthase activity
GPY07_RS09960	COG0148	phosphopyruvate hydratase activity
GPY07_RS09965	COG0617	tRNA 3'-terminal CCA addition
GPY07_RS09970	COG3409	Peptidoglycan-binding domain 1 protein
GPY07_RS09970	COG3267	Type II secretory pathway component ExeA
GPY07_RS09980	COG4991	sh3 domain protein
GPY07_RS09985	COG0306	phosphate transporter
GPY07_RS09990	COG1392	Phosphate transport regulator
GPY07_RS09995	COG3025	triphosphatase activity
GPY07_RS10000	COG0840	transmembrane signaling receptor activity
GPY07_RS10005	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GPY07_RS10015	COG1538	Outer membrane efflux protein
GPY07_RS10020	COG0494	nUDIX hydrolase
GPY07_RS10025	COG3151	Protein conserved in bacteria
GPY07_RS10035	COG3150	esterase
GPY07_RS10040	COG0187	DNA topoisomerase II activity
GPY07_RS10045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPY07_RS10050	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GPY07_RS10055	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GPY07_RS10060	COG0237	dephospho-CoA kinase activity
GPY07_RS10070	COG1459	type II secretion system
GPY07_RS10075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY07_RS10095	COG0716	FMN binding
GPY07_RS10100	COG4974	Belongs to the 'phage' integrase family
GPY07_RS10105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY07_RS10110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GPY07_RS10115	COG0737	Belongs to the 5'-nucleotidase family
GPY07_RS10120	COG2186	Transcriptional regulator
GPY07_RS10125	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GPY07_RS10130	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY07_RS10135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY07_RS10145	COG0275	rRNA processing
GPY07_RS10150	COG3116	cell division
GPY07_RS10155	COG0768	penicillin binding
GPY07_RS10160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPY07_RS10165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GPY07_RS10170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPY07_RS10175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPY07_RS10180	COG0772	Belongs to the SEDS family
GPY07_RS10185	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPY07_RS10190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPY07_RS10195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GPY07_RS10200	COG0849	cell division
GPY07_RS10205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPY07_RS10210	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GPY07_RS10220	COG0653	protein targeting
GPY07_RS10225	COG0494	nUDIX hydrolase
GPY07_RS10230	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GPY07_RS10240	COG0505	Belongs to the CarA family
GPY07_RS10245	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GPY07_RS10260	COG4172	Belongs to the ABC transporter superfamily
GPY07_RS10270	COG0730	response to heat
GPY07_RS10275	COG0583	DNA-binding transcription factor activity
GPY07_RS10280	COG2860	membrane
GPY07_RS10285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY07_RS10295	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPY07_RS10305	COG0493	'glutamate synthase
GPY07_RS10310	COG0069	glutamate synthase activity
GPY07_RS10310	COG0070	glutamate synthase
GPY07_RS10310	COG0067	glutamate synthase
GPY07_RS10320	COG0070	glutamate synthase
GPY07_RS10320	COG0067	glutamate synthase
GPY07_RS10320	COG0069	glutamate synthase activity
GPY07_RS10325	COG1242	4 iron, 4 sulfur cluster binding
GPY07_RS10330	COG4251	negative regulation of phosphorylation
GPY07_RS10330	COG3706	GGDEF domain
GPY07_RS10330	COG2203	Gaf domain
GPY07_RS10330	COG5001	Diguanylate cyclase
GPY07_RS10335	COG2198	Histidine kinase
GPY07_RS10335	COG0784	Response regulator, receiver
GPY07_RS10335	COG5002	protein histidine kinase activity
GPY07_RS10340	COG0745	RESPONSE REGULATOR receiver
GPY07_RS10350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPY07_RS10370	COG0083	homoserine kinase activity
GPY07_RS10375	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPY07_RS10380	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
GPY07_RS10385	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GPY07_RS10390	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPY07_RS10405	COG1115	amino acid carrier protein
GPY07_RS10420	COG0084	hydrolase, TatD family'
GPY07_RS10425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY07_RS10435	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPY07_RS10440	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GPY07_RS10445	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPY07_RS10450	COG0813	purine-nucleoside phosphorylase activity
GPY07_RS10460	COG0560	Phosphoserine phosphatase
GPY07_RS10470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPY07_RS10475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPY07_RS10480	COG1022	Amp-dependent synthetase and ligase
GPY07_RS10495	COG3250	beta-galactosidase activity
GPY07_RS10500	COG1609	Transcriptional regulator
GPY07_RS10505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY07_RS10520	COG0189	ligase activity
GPY07_RS10520	COG0569	domain protein
GPY07_RS10525	COG0456	acetyltransferase
GPY07_RS10535	COG2171	N-acyltransferase activity
GPY07_RS10540	COG3141	response to X-ray
GPY07_RS10555	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GPY07_RS10560	COG1074	ATP-dependent DNA helicase activity
GPY07_RS10565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GPY07_RS10575	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPY07_RS10575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPY07_RS10585	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GPY07_RS10590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GPY07_RS10595	COG2166	iron-sulfur cluster assembly
GPY07_RS10600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPY07_RS10605	COG0693	protein deglycase activity
GPY07_RS10610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPY07_RS10615	COG3248	Nucleoside-binding outer membrane protein
GPY07_RS10625	COG1595	DNA-templated transcription, initiation
GPY07_RS10635	COG2211	Major facilitator Superfamily
GPY07_RS10645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPY07_RS10655	COG2813	Specifically methylates the guanine in position
GPY07_RS10660	COG0271	Belongs to the BolA IbaG family
GPY07_RS10665	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY07_RS10670	COG1805	sodium ion transport
GPY07_RS10675	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY07_RS10680	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY07_RS10685	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY07_RS10690	COG2871	sodium ion transport
GPY07_RS10695	COG1477	protein flavinylation
GPY07_RS10705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPY07_RS10720	COG0733	neurotransmitter:sodium symporter activity
GPY07_RS10730	COG0189	ligase activity
GPY07_RS10735	COG4067	protein conserved in archaea
GPY07_RS10735	COG0189	ligase activity
GPY07_RS10745	COG2252	PERMEase
GPY07_RS10750	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GPY07_RS10765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPY07_RS10770	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPY07_RS10775	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPY07_RS10780	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY07_RS10780	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY07_RS10795	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GPY07_RS10800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPY07_RS10805	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GPY07_RS10810	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GPY07_RS10820	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GPY07_RS10825	COG0024	Methionine aminopeptidase
GPY07_RS10830	COG0052	Belongs to the universal ribosomal protein uS2 family
GPY07_RS10835	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPY07_RS10840	COG0528	UMP kinase activity
GPY07_RS10845	COG0233	cytoplasmic translational termination
GPY07_RS10850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPY07_RS10855	COG0575	Belongs to the CDS family
GPY07_RS10860	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GPY07_RS10865	COG0750	zinc metalloprotease
GPY07_RS10875	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GPY07_RS10880	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY07_RS10885	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY07_RS10890	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY07_RS10895	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY07_RS10900	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPY07_RS10905	COG0587	DNA-directed DNA polymerase activity
GPY07_RS10910	COG0825	malonyl-CoA metabolic process
GPY07_RS10915	COG0037	tRNA processing
GPY07_RS10925	COG3479	Phenolic acid decarboxylase
GPY07_RS10930	COG0347	Belongs to the P(II) protein family
GPY07_RS10940	COG1388	LysM domain
GPY07_RS10940	COG0741	lytic transglycosylase activity
GPY07_RS10945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY07_RS10950	COG2226	methyltransferase
GPY07_RS10955	COG0328	RNA-DNA hybrid ribonuclease activity
GPY07_RS10960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPY07_RS10970	COG1960	acyl-CoA dehydrogenase activity
GPY07_RS10975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPY07_RS10980	COG0121	glutamine amidotransferase
GPY07_RS10985	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPY07_RS10990	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GPY07_RS10995	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPY07_RS11000	COG3706	GGDEF domain
GPY07_RS11005	COG1187	pseudouridine synthase activity
GPY07_RS11010	COG2840	Smr protein MutS2
GPY07_RS11025	COG3735	TraB family
GPY07_RS11040	COG2217	Heavy metal translocating P-type atpase
GPY07_RS11040	COG2608	mercury ion transmembrane transporter activity
GPY07_RS11045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY07_RS11060	COG4774	siderophore transport
GPY07_RS11060	COG1629	transport
GPY07_RS11065	COG2375	cellular response to nickel ion
GPY07_RS11105	COG0784	Response regulator, receiver
GPY07_RS11105	COG0835	chemotaxis
GPY07_RS11110	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPY07_RS11115	COG1815	bacterial-type flagellum-dependent cell motility
GPY07_RS11120	COG1558	bacterial-type flagellum-dependent cell motility
GPY07_RS11125	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPY07_RS11130	COG1749	Flagellar hook protein flgE
GPY07_RS11135	COG4787	bacterial-type flagellum-dependent cell motility
GPY07_RS11140	COG4786	Flagellar basal body rod
GPY07_RS11145	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GPY07_RS11150	COG1706	bacterial-type flagellum-dependent cell motility
GPY07_RS11155	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPY07_RS11155	COG3951	Flagellar rod assembly protein muramidase FlgJ
GPY07_RS11175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY07_RS11180	COG4974	Belongs to the 'phage' integrase family
GPY07_RS11275	COG4695	Portal protein
GPY07_RS11395	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY07_RS11480	COG0012	GTP binding
GPY07_RS11485	COG0193	aminoacyl-tRNA hydrolase activity
GPY07_RS11490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPY07_RS11495	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPY07_RS11500	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GPY07_RS11505	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPY07_RS11510	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPY07_RS11515	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY07_RS11520	COG3094	Invasion gene expression up-regulator, SirB
GPY07_RS11525	COG2912	Transglutaminase-like superfamily
GPY07_RS11530	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GPY07_RS11535	COG0737	Belongs to the 5'-nucleotidase family
GPY07_RS11540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPY07_RS11545	COG2233	PERMEase
GPY07_RS11565	COG1393	Belongs to the ArsC family
GPY07_RS11570	COG4783	chaperone-mediated protein folding
GPY07_RS11585	COG0840	transmembrane signaling receptor activity
GPY07_RS11590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPY07_RS11605	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GPY07_RS11615	COG1876	peptidase activity
GPY07_RS11620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY07_RS11625	COG1393	Belongs to the ArsC family
GPY07_RS11645	COG2837	iron assimilation
GPY07_RS11650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY07_RS11655	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY07_RS11660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY07_RS11665	COG1334	flagellar protein FlaG
GPY07_RS11670	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPY07_RS11680	COG1516	flagellar protein fliS
GPY07_RS11685	COG2204	response regulator
GPY07_RS11690	COG4191	Histidine kinase
GPY07_RS11695	COG2204	response regulator
GPY07_RS11700	COG1677	Flagellar hook-basal body complex protein FliE
GPY07_RS11710	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY07_RS11715	COG1317	bacterial-type flagellum organization
GPY07_RS11740	COG1580	Controls the rotational direction of flagella during chemotaxis
GPY07_RS11765	COG1987	bacterial-type flagellum assembly
GPY07_RS11770	COG1684	flagellar biosynthetic protein fliR
GPY07_RS11785	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY07_RS11790	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPY07_RS11795	COG2860	membrane
GPY07_RS11800	COG3101	peptidyl-lysine hydroxylation
GPY07_RS11810	COG0431	NADPH-dependent FMN reductase
GPY07_RS11815	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GPY07_RS11815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY07_RS11820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPY07_RS11825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY07_RS11830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPY07_RS11835	COG0735	belongs to the Fur family
GPY07_RS11845	COG0583	DNA-binding transcription factor activity
GPY07_RS11855	COG1346	cytolysis
GPY07_RS11870	COG0596	Alpha beta hydrolase
GPY07_RS11875	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GPY07_RS11880	COG0033	Phosphoglucomutase
GPY07_RS11890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPY07_RS11895	COG0372	Belongs to the citrate synthase family
GPY07_RS11900	COG2009	succinate dehydrogenase
GPY07_RS11905	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GPY07_RS11910	COG1053	succinate dehydrogenase
GPY07_RS11920	COG0567	Dehydrogenase, E1 component
GPY07_RS11925	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY07_RS11930	COG0045	succinate-CoA ligase (ADP-forming) activity
GPY07_RS11940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPY07_RS11945	COG1121	(ABC) transporter
GPY07_RS11950	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GPY07_RS11955	COG4977	sequence-specific DNA binding
GPY07_RS11960	COG1918	ferrous iron import across plasma membrane
GPY07_RS11980	COG0018	arginyl-trna synthetase
GPY07_RS11990	COG1025	Belongs to the peptidase M16 family
GPY07_RS11995	COG2062	phosphohistidine phosphatase, SixA
GPY07_RS12010	COG0455	bacterial-type flagellum organization
GPY07_RS12025	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GPY07_RS12030	COG2198	Histidine kinase
GPY07_RS12030	COG0643	Histidine kinase
GPY07_RS12035	COG2201	protein-glutamate methylesterase activity
GPY07_RS12040	COG1192	Involved in chromosome partitioning
GPY07_RS12050	COG0835	chemotaxis
GPY07_RS12060	COG4133	protoheme IX ABC transporter activity
GPY07_RS12065	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY07_RS12070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY07_RS12080	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GPY07_RS12085	COG1138	Cytochrome C-type biogenesis protein
GPY07_RS12090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY07_RS12095	COG3088	subunit of a heme lyase
GPY07_RS12095	COG4235	cytochrome complex assembly
GPY07_RS12105	COG2853	Lipoprotein
GPY07_RS12125	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GPY07_RS12130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY07_RS12135	COG0123	including yeast histone deacetylase and acetoin utilization protein
GPY07_RS12150	COG3083	sulfuric ester hydrolase activity
GPY07_RS12160	COG3081	Nucleoid-associated protein
GPY07_RS12170	COG1757	Na H antiporter
GPY07_RS12175	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPY07_RS12180	COG2095	MarC family integral membrane protein
GPY07_RS12185	COG1012	belongs to the aldehyde dehydrogenase family
GPY07_RS12185	COG1454	alcohol dehydrogenase
GPY07_RS12195	COG0659	secondary active sulfate transmembrane transporter activity
GPY07_RS12200	COG1530	ribonuclease E activity
GPY07_RS12205	COG0564	pseudouridine synthase activity
GPY07_RS12210	COG0424	maF-like protein
GPY07_RS12215	COG1399	metal-binding, possibly nucleic acid-binding protein
GPY07_RS12220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GPY07_RS12225	COG0416	fatty acid biosynthetic process
GPY07_RS12230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY07_RS12235	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GPY07_RS12240	COG1028	Short-chain dehydrogenase reductase Sdr
GPY07_RS12245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY07_RS12250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPY07_RS12255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPY07_RS12260	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPY07_RS12265	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPY07_RS12275	COG0084	hydrolase, TatD family'
GPY07_RS12280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY07_RS12280	COG1263	PTS System
GPY07_RS12290	COG0733	neurotransmitter:sodium symporter activity
GPY07_RS12305	COG4667	esterase of the alpha-beta hydrolase superfamily
GPY07_RS12315	COG1940	carbohydrate kinase activity
GPY07_RS12320	COG0784	Response regulator, receiver
GPY07_RS12320	COG0835	chemotaxis
GPY07_RS12335	COG2226	methyltransferase
GPY07_RS12345	COG0676	glucose-6-phosphate 1-epimerase activity
GPY07_RS12350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY07_RS12355	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY07_RS12365	COG3139	Protein of unknown function (DUF1315)
GPY07_RS12370	COG0252	asparaginase activity
GPY07_RS12375	COG0616	signal peptide processing
GPY07_RS12380	COG1902	pentaerythritol trinitrate reductase activity
GPY07_RS12380	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPY07_RS12385	COG0788	formyltetrahydrofolate deformylase activity
GPY07_RS12395	COG1199	ATP-dependent helicase activity
GPY07_RS12400	COG1214	PFAM Peptidase M22, glycoprotease
GPY07_RS12415	COG0596	Alpha beta hydrolase
GPY07_RS12420	COG0318	PFAM AMP-dependent synthetase and ligase
GPY07_RS12425	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GPY07_RS12445	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GPY07_RS12450	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GPY07_RS12455	COG0436	Aminotransferase
GPY07_RS12460	COG1169	isochorismate synthase
GPY07_RS12465	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GPY07_RS12470	COG0596	Alpha beta hydrolase
GPY07_RS12480	COG1441	menaquinone biosynthetic process
GPY07_RS12490	COG3135	benzoate transporter
GPY07_RS12495	COG1396	sequence-specific DNA binding
GPY07_RS12500	COG0840	transmembrane signaling receptor activity
GPY07_RS12505	COG0477	Major facilitator Superfamily
GPY07_RS12525	COG3015	lipoprotein NlpE involved in copper resistance
GPY07_RS12530	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GPY07_RS12535	COG2894	cell division
GPY07_RS12540	COG0850	regulation of cytokinetic process
GPY07_RS12545	COG3100	YcgL domain-containing protein
GPY07_RS12550	COG2951	lytic endotransglycosylase activity
GPY07_RS12560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY07_RS12565	COG3325	Belongs to the glycosyl hydrolase 18 family
GPY07_RS12565	COG3469	chitinase activity
GPY07_RS12570	COG3005	denitrification pathway
GPY07_RS12575	COG0243	molybdopterin cofactor binding
GPY07_RS12595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY07_RS12605	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPY07_RS12640	COG4589	Belongs to the CDS family
GPY07_RS12650	COG3300	MHYT domain
GPY07_RS12650	COG5001	Diguanylate cyclase
GPY07_RS12665	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GPY07_RS12670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPY07_RS12675	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GPY07_RS12680	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GPY07_RS12690	COG4191	Histidine kinase
GPY07_RS12700	COG0544	peptidyl-prolyl cis-trans isomerase activity
GPY07_RS12710	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPY07_RS12715	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPY07_RS12720	COG0776	regulation of translation
GPY07_RS12725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY07_RS12730	COG1555	photosystem II stabilization
GPY07_RS12735	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GPY07_RS12740	COG0539	negative regulation of cytoplasmic translation
GPY07_RS12745	COG0776	regulation of translation
GPY07_RS12750	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GPY07_RS12755	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GPY07_RS12760	COG0284	orotidine-5'-phosphate decarboxylase activity
GPY07_RS12775	COG0583	DNA-binding transcription factor activity
GPY07_RS12785	COG0686	Belongs to the AlaDH PNT family
GPY07_RS12800	COG1674	ftsk spoiiie
GPY07_RS12805	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GPY07_RS12810	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPY07_RS12815	COG2186	Transcriptional regulator
GPY07_RS12830	COG0537	adenosine 5'-monophosphoramidase activity
GPY07_RS12860	COG1252	NADH dehydrogenase
GPY07_RS12880	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPY07_RS12890	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPY07_RS12895	COG1136	(ABC) transporter
GPY07_RS12900	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPY07_RS12915	COG2333	competence protein COMEC
GPY07_RS12915	COG0658	competence protein
GPY07_RS12920	COG1132	(ABC) transporter
GPY07_RS12925	COG1663	tetraacyldisaccharide 4'-kinase activity
GPY07_RS12935	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GPY07_RS12940	COG2719	SpoVR family
GPY07_RS12945	COG2718	Belongs to the UPF0229 family
GPY07_RS12950	COG2766	serine protein kinase
GPY07_RS12955	COG3013	Belongs to the UPF0304 family
GPY07_RS12965	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY07_RS12970	COG0840	transmembrane signaling receptor activity
GPY07_RS12980	COG1882	Formate acetyltransferase
GPY07_RS13000	COG4215	(ABC) transporter
GPY07_RS13005	COG4160	amino acid transport
GPY07_RS13010	COG0708	Exodeoxyribonuclease III
GPY07_RS13015	COG0840	transmembrane signaling receptor activity
GPY07_RS13025	COG3923	Primosomal replication protein n
GPY07_RS13030	COG0730	response to heat
GPY07_RS13035	COG1199	ATP-dependent helicase activity
GPY07_RS13040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPY07_RS13045	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPY07_RS13055	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY07_RS13060	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY07_RS13065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPY07_RS13070	COG0215	cysteine-tRNA ligase activity
GPY07_RS13075	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GPY07_RS13080	COG0632	four-way junction helicase activity
GPY07_RS13085	COG2255	four-way junction helicase activity
GPY07_RS13090	COG1271	oxidase subunit
GPY07_RS13095	COG1294	oxidase, subunit
GPY07_RS13100	COG4890	Cyd operon protein YbgT
GPY07_RS13105	COG3790	cyd operon protein YbgE
GPY07_RS13110	COG0824	Thioesterase
GPY07_RS13115	COG0811	peptide transport
GPY07_RS13130	COG0823	Involved in the tonB-independent uptake of proteins
GPY07_RS13135	COG2885	chlorophyll binding
GPY07_RS13155	COG5002	protein histidine kinase activity
GPY07_RS13155	COG0784	Response regulator, receiver
GPY07_RS13165	COG1482	cell wall glycoprotein biosynthetic process
GPY07_RS13170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY07_RS13170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY07_RS13170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY07_RS13175	COG2207	Transcriptional regulator
GPY07_RS13185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY07_RS13190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY07_RS13195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY07_RS13205	COG1012	belongs to the aldehyde dehydrogenase family
GPY07_RS13210	COG3284	Transcriptional regulator
GPY07_RS13215	COG4628	conserved protein (DUF2132)
GPY07_RS13225	COG0415	Belongs to the DNA photolyase family
GPY07_RS13305	COG0488	(ABC) transporter
GPY07_RS13345	COG3941	tape measure
GPY07_RS13360	COG0582	viral genome integration into host DNA
GPY07_RS13365	COG0582	viral genome integration into host DNA
GPY07_RS13380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY07_RS13390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPY07_RS13390	COG3008	intermembrane lipid transfer
GPY07_RS13400	COG0668	transmembrane transport
GPY07_RS13420	COG1309	transcriptional regulator
GPY07_RS13425	COG1012	belongs to the aldehyde dehydrogenase family
GPY07_RS13450	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPY07_RS13455	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPY07_RS13460	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GPY07_RS13465	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GPY07_RS13475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GPY07_RS13485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY07_RS13490	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPY07_RS13495	COG0297	glycogen (starch) synthase activity
GPY07_RS13515	COG3070	regulator of competence-specific genes
GPY07_RS13520	COG1609	Transcriptional regulator
GPY07_RS13525	COG3381	protein complex oligomerization
GPY07_RS13530	COG0745	RESPONSE REGULATOR receiver
GPY07_RS13535	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPY07_RS13540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY07_RS13545	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GPY07_RS13550	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GPY07_RS13555	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GPY07_RS13570	COG1032	radical SAM domain protein
GPY07_RS13580	COG0612	Peptidase, M16
GPY07_RS13595	COG0583	DNA-binding transcription factor activity
GPY07_RS13600	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPY07_RS13610	COG2350	Protein conserved in bacteria
GPY07_RS13615	COG1607	acyl-coa hydrolase
GPY07_RS13620	COG2917	probably involved in intracellular septation
GPY07_RS13630	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPY07_RS13635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY07_RS13645	COG2116	formate transmembrane transporter activity
GPY07_RS13655	COG4459	periplasmic nitrate reductase
GPY07_RS13660	COG3005	denitrification pathway
GPY07_RS13665	COG0243	molybdopterin cofactor binding
GPY07_RS13685	COG1227	inorganic diphosphatase activity
GPY07_RS13700	COG4172	Belongs to the ABC transporter superfamily
GPY07_RS13710	COG4171	peptide transport system, permease
GPY07_RS13715	COG4168	peptide transport system, permease
GPY07_RS13725	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GPY07_RS13730	COG1842	Phage shock protein A
GPY07_RS13745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY07_RS13760	COG2818	Glycosylase
GPY07_RS13765	COG0626	cystathionine gamma-synthase activity
GPY07_RS13775	COG0733	neurotransmitter:sodium symporter activity
GPY07_RS13780	COG0564	pseudouridine synthase activity
GPY07_RS13785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPY07_RS13790	COG4136	ATPase activity
GPY07_RS13800	COG4134	Bacterial extracellular solute-binding protein
GPY07_RS13810	COG3313	Fe-S protein
GPY07_RS13820	COG0842	Transport permease protein
GPY07_RS13825	COG1131	(ABC) transporter
GPY07_RS13830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY07_RS13835	COG0814	amino acid
GPY07_RS13845	COG2239	Acts as a magnesium transporter
GPY07_RS13865	COG4934	collagen metabolic process
GPY07_RS13895	COG0840	transmembrane signaling receptor activity
GPY07_RS13905	COG5001	Diguanylate cyclase
GPY07_RS13905	COG3706	GGDEF domain
GPY07_RS13905	COG2203	Gaf domain
GPY07_RS13905	COG4251	negative regulation of phosphorylation
GPY07_RS13910	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GPY07_RS13930	COG1061	Type III restriction enzyme res subunit
GPY07_RS13935	COG1187	pseudouridine synthase activity
GPY07_RS13940	COG2814	Major facilitator Superfamily
GPY07_RS13950	COG0702	epimerase
GPY07_RS13955	COG0534	Mate efflux family protein
GPY07_RS13960	COG4181	ATPase activity
GPY07_RS13975	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPY07_RS13985	COG1748	Saccharopine dehydrogenase
GPY07_RS13990	COG0019	diaminopimelate decarboxylase activity
GPY07_RS14000	COG1538	Outer membrane efflux protein
GPY07_RS14020	COG0583	DNA-binding transcription factor activity
GPY07_RS14030	COG1451	nucleotide metabolic process
GPY07_RS14035	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GPY07_RS14045	COG3063	Type IV pilus biogenesis stability protein PilW
GPY07_RS14050	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GPY07_RS14070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY07_RS14085	COG3290	protein histidine kinase activity
GPY07_RS14090	COG4565	transcriptional regulatory protein
GPY07_RS14100	COG0835	chemotaxis
GPY07_RS14100	COG0784	Response regulator, receiver
GPY07_RS14120	COG3706	GGDEF domain
GPY07_RS14120	COG0745	RESPONSE REGULATOR receiver
GPY07_RS14145	COG1085	galactose-1-phosphate uridylyltransferase
GPY07_RS14150	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPY07_RS14155	COG2017	converts alpha-aldose to the beta-anomer
GPY07_RS14160	COG3706	GGDEF domain
GPY07_RS14165	COG2199	diguanylate cyclase activity
GPY07_RS14165	COG2200	EAL domain
GPY07_RS14180	COG3527	Alpha-acetolactate decarboxylase
GPY07_RS14195	COG0753	catalase activity
GPY07_RS14215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GPY07_RS14225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY07_RS14265	COG1368	sulfuric ester hydrolase activity
GPY07_RS14270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY07_RS14285	COG0546	phosphoglycolate phosphatase activity
GPY07_RS14325	COG0484	heat shock protein binding
GPY07_RS14340	COG1716	ATPase activity
GPY07_RS14340	COG5001	Diguanylate cyclase
GPY07_RS14345	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPY07_RS14355	COG4181	ATPase activity
GPY07_RS14360	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GPY07_RS14375	COG1984	allophanate hydrolase subunit 2
GPY07_RS14385	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GPY07_RS14390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPY07_RS14395	COG0840	transmembrane signaling receptor activity
GPY07_RS14400	COG0814	amino acid
GPY07_RS14410	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GPY07_RS14415	COG0513	Belongs to the DEAD box helicase family
GPY07_RS14420	COG1309	transcriptional regulator
GPY07_RS14430	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GPY07_RS14435	COG0494	nUDIX hydrolase
GPY07_RS14445	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GPY07_RS14455	COG1126	abc transporter atp-binding protein
GPY07_RS14460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY07_RS14465	COG4215	(ABC) transporter
GPY07_RS14470	COG4160	amino acid transport
GPY07_RS14475	COG0583	DNA-binding transcription factor activity
GPY07_RS14505	COG3118	belongs to the thioredoxin family
GPY07_RS14515	COG0247	lactate metabolic process
GPY07_RS14520	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GPY07_RS14525	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPY07_RS14530	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPY07_RS14535	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPY07_RS14565	COG2827	Endonuclease containing a URI domain
GPY07_RS14575	COG1879	ABC-type sugar transport system periplasmic component
GPY07_RS14580	COG5002	protein histidine kinase activity
GPY07_RS14580	COG0784	Response regulator, receiver
GPY07_RS14625	COG1492	cobalamin metabolic process
GPY07_RS14630	COG0725	ABC transporter, periplasmic molybdate-binding protein
GPY07_RS14635	COG4149	molybdate abc transporter
GPY07_RS14640	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GPY07_RS14670	COG1289	transmembrane transporter activity
GPY07_RS14675	COG0210	DNA helicase
GPY07_RS14690	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPY07_RS14695	COG1335	isochorismatase
GPY07_RS14700	COG1803	Methylglyoxal synthase
GPY07_RS14705	COG1879	ABC-type sugar transport system periplasmic component
GPY07_RS14710	COG0784	Response regulator, receiver
GPY07_RS14710	COG2205	protein histidine kinase activity
GPY07_RS14710	COG2198	Histidine kinase
GPY07_RS14715	COG0469	pyruvate kinase activity
GPY07_RS14720	COG2271	Major facilitator Superfamily
GPY07_RS14725	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY07_RS14730	COG4191	Histidine kinase
GPY07_RS14745	COG1979	alcohol dehydrogenase
GPY07_RS14755	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPY07_RS14760	COG3706	GGDEF domain
GPY07_RS14825	COG2131	deaminase
GPY07_RS14840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY07_RS14845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY07_RS14855	COG0183	Belongs to the thiolase family
GPY07_RS14865	COG3243	poly(R)-hydroxyalkanoic acid synthase
GPY07_RS14870	COG3842	ATPase activity
GPY07_RS14880	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY07_RS14885	COG2271	Major facilitator Superfamily
GPY07_RS14890	COG3851	Histidine kinase
GPY07_RS14895	COG2197	response regulator
GPY07_RS14900	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPY07_RS14920	COG0243	molybdopterin cofactor binding
GPY07_RS14930	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPY07_RS14935	COG3850	Histidine kinase
GPY07_RS14940	COG2197	response regulator
GPY07_RS14945	COG1609	Transcriptional regulator
GPY07_RS14965	COG1760	l-serine dehydratase
GPY07_RS14970	COG3069	C4-dicarboxylate transmembrane transporter activity
GPY07_RS14975	COG0840	transmembrane signaling receptor activity
GPY07_RS14980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY07_RS14985	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY07_RS14990	COG2885	chlorophyll binding
GPY07_RS15000	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPY07_RS15005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY07_RS15010	COG1621	beta-fructofuranosidase activity
GPY07_RS15020	COG1263	PTS System
GPY07_RS15020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY07_RS15065	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPY07_RS15075	COG0640	Transcriptional regulator
GPY07_RS15105	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GPY07_RS15110	COG0583	DNA-binding transcription factor activity
GPY07_RS15135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY07_RS15160	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPY07_RS15165	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPY07_RS15175	COG2390	Transcriptional regulator
GPY07_RS15180	COG2897	thiosulfate sulfurtransferase activity
GPY07_RS15190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY07_RS15200	COG0302	gtp cyclohydrolase
GPY07_RS15205	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY07_RS15205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY07_RS15210	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GPY07_RS15215	COG1970	mechanosensitive ion channel activity
GPY07_RS15220	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GPY07_RS15230	COG1011	Hydrolase
GPY07_RS15235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY07_RS15240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY07_RS15250	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPY07_RS15260	COG3842	ATPase activity
GPY07_RS15305	COG4166	transmembrane transport
GPY07_RS15310	COG4174	ABC transporter (Permease)
GPY07_RS15315	COG4239	(ABC) transporter, permease
GPY07_RS15320	COG4172	Belongs to the ABC transporter superfamily
GPY07_RS15325	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPY07_RS15340	COG0625	glutathione transferase activity
GPY07_RS15360	COG2050	protein possibly involved in aromatic compounds catabolism
GPY07_RS15375	COG4771	TonB-dependent receptor
GPY07_RS15375	COG1629	transport
GPY07_RS15380	COG0583	DNA-binding transcription factor activity
GPY07_RS15385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY07_RS15385	COG1042	CoA-binding domain protein
GPY07_RS15385	COG0045	succinate-CoA ligase (ADP-forming) activity
GPY07_RS15395	COG1181	Belongs to the D-alanine--D-alanine ligase family
GPY07_RS15405	COG0023	Translation Initiation Factor
GPY07_RS15425	COG0745	RESPONSE REGULATOR receiver
GPY07_RS15435	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GPY07_RS15440	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GPY07_RS15455	COG3706	GGDEF domain
GPY07_RS15510	COG2824	Alkylphosphonate utilization operon protein PhnA
GPY07_RS15530	COG0737	Belongs to the 5'-nucleotidase family
GPY07_RS15535	COG3593	DNA synthesis involved in DNA repair
GPY07_RS15545	COG0583	DNA-binding transcription factor activity
GPY07_RS15550	COG2116	formate transmembrane transporter activity
GPY07_RS15560	COG3038	cytochrome b561
GPY07_RS15570	COG2200	EAL domain
GPY07_RS15580	COG0586	Pfam SNARE associated Golgi protein
GPY07_RS15585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPY07_RS15590	COG0745	RESPONSE REGULATOR receiver
GPY07_RS15595	COG2205	protein histidine kinase activity
GPY07_RS15600	COG0674	pyruvate-flavodoxin oxidoreductase activity
GPY07_RS15600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GPY07_RS15600	COG1013	pyruvate-flavodoxin oxidoreductase activity
GPY07_RS15600	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GPY07_RS15605	COG3158	transport of potassium into the cell
GPY07_RS15615	COG0523	cobalamin synthesis protein
GPY07_RS15630	COG0156	8-amino-7-oxononanoate synthase activity
GPY07_RS15635	COG0784	Response regulator, receiver
GPY07_RS15635	COG2205	protein histidine kinase activity
GPY07_RS15640	COG0419	ATPase involved in DNA repair
GPY07_RS15645	COG0420	3'-5' exonuclease activity
GPY07_RS15650	COG1609	Transcriptional regulator
GPY07_RS15655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY07_RS15655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY07_RS15660	COG1105	Belongs to the carbohydrate kinase PfkB family
GPY07_RS15665	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GPY07_RS15665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY07_RS15665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY07_RS15670	COG0189	ligase activity
GPY07_RS15670	COG4067	protein conserved in archaea
GPY07_RS15680	COG0602	queuosine metabolic process
GPY07_RS15685	COG1328	CTP reductase activity
GPY07_RS15710	COG0346	lactoylglutathione lyase activity
GPY07_RS15775	COG1943	Transposase
GPY07_RS15870	COG0346	lactoylglutathione lyase activity
GPY07_RS15890	COG0110	maltose O-acetyltransferase activity
GPY07_RS15895	COG3039	Transposase
GPY07_RS15910	COG2944	sequence-specific DNA binding
GPY07_RS15915	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
GPY07_RS16005	COG4977	sequence-specific DNA binding
GPY07_RS16070	COG3040	lipid binding
GPY07_RS16095	COG1619	proteins homologs of microcin C7 resistance protein MccF
GPY07_RS16115	COG3093	addiction module antidote protein HigA
GPY07_RS16120	COG3549	Plasmid maintenance system killer
GPY07_RS16325	COG1280	lysine exporter protein (LysE YggA)
GPY07_RS16335	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPY07_RS16420	COG3041	Addiction module toxin RelE StbE family
GPY07_RS16455	COG3040	lipid binding
GPY07_RS16460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY07_RS16480	COG0494	nUDIX hydrolase
GPY07_RS16510	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GPY07_RS16545	COG1028	Short-chain dehydrogenase reductase Sdr
GPY07_RS16605	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GPY07_RS16610	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GPY07_RS16620	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPY07_RS16645	COG3039	Transposase
GPY07_RS16655	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GPY07_RS16665	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPY07_RS16670	COG0509	glycine decarboxylation via glycine cleavage system
GPY07_RS16675	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPY07_RS16675	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPY07_RS16685	COG1943	Transposase
GPY07_RS16705	COG1686	Belongs to the peptidase S11 family
GPY07_RS16720	COG2814	Major facilitator Superfamily
GPY07_RS16735	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GPY07_RS16760	COG5002	protein histidine kinase activity
GPY07_RS16765	COG0745	RESPONSE REGULATOR receiver
GPY07_RS16790	COG0366	Alpha amylase catalytic
GPY07_RS16795	COG3038	cytochrome b561
GPY07_RS16825	COG0561	phosphatase activity
GPY07_RS16830	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GPY07_RS16835	COG3623	hexulose-6-phosphate isomerase
GPY07_RS16845	COG0745	RESPONSE REGULATOR receiver
GPY07_RS16865	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPY07_RS16885	COG4604	ABC transporter, ATP-binding protein
GPY07_RS16890	COG4605	iron ion homeostasis
GPY07_RS16895	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY07_RS16915	COG3291	Pkd domain containing protein
GPY07_RS16915	COG4412	M6 family metalloprotease domain protein
GPY07_RS16920	COG5380	lipid catabolic process
GPY07_RS16925	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPY07_RS16930	COG0840	transmembrane signaling receptor activity
GPY07_RS16940	COG3240	lipase activity
GPY07_RS16945	COG3706	GGDEF domain
GPY07_RS16955	COG2814	Major facilitator Superfamily
GPY07_RS16960	COG1757	Na H antiporter
GPY07_RS16970	COG4191	Histidine kinase
GPY07_RS16970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY07_RS16975	COG0784	Response regulator, receiver
GPY07_RS16975	COG3437	response regulator, receiver
GPY07_RS16985	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPY07_RS16990	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GPY07_RS16995	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPY07_RS17000	COG0513	Belongs to the DEAD box helicase family
GPY07_RS17015	COG1943	Transposase
GPY07_RS17040	COG0516	GMP reductase activity
GPY07_RS17050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPY07_RS17060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY07_RS17065	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GPY07_RS17065	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPY07_RS17090	COG3036	rescue of stalled ribosome
GPY07_RS17095	COG1278	Cold shock
GPY07_RS17100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY07_RS17100	COG1017	nitric oxide dioxygenase activity
GPY07_RS17105	COG3604	Transcriptional regulator
GPY07_RS17115	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY07_RS17120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY07_RS17135	COG0840	transmembrane signaling receptor activity
GPY07_RS17140	COG0714	Associated with various cellular activities
GPY07_RS17160	COG2304	oxidoreductase activity
GPY07_RS17175	COG1278	Cold shock
GPY07_RS17180	COG5001	Diguanylate cyclase
GPY07_RS17180	COG5002	protein histidine kinase activity
GPY07_RS17190	COG3530	Putative quorum-sensing-regulated virulence factor
GPY07_RS17200	COG3033	Beta-eliminating lyase
GPY07_RS17205	COG0814	amino acid
GPY07_RS17210	COG0589	response to stress
GPY07_RS17220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GPY07_RS17220	COG2111	Na H antiporter
GPY07_RS17240	COG2212	antiporter activity
GPY07_RS17245	COG1320	monovalent cation:proton antiporter activity
GPY07_RS17255	COG0242	peptide deformylase activity
GPY07_RS17265	COG0579	oxidoreductase
GPY07_RS17305	COG2271	Major facilitator Superfamily
GPY07_RS17310	COG0584	glycerophosphoryl diester phosphodiesterase
GPY07_RS17320	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GPY07_RS17330	COG1609	Transcriptional regulator
GPY07_RS17335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY07_RS17340	COG1879	ABC-type sugar transport system periplasmic component
GPY07_RS17345	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPY07_RS17350	COG1129	ABC transporter
GPY07_RS17355	COG1869	D-ribose catabolic process
GPY07_RS17370	COG3501	Rhs element vgr protein
GPY07_RS17465	COG0564	pseudouridine synthase activity
GPY07_RS17475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY07_RS17480	COG2771	luxR family
GPY07_RS17480	COG2200	EAL domain
GPY07_RS17490	COG0673	inositol 2-dehydrogenase activity
GPY07_RS17495	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPY07_RS17525	COG1342	Belongs to the UPF0251 family
GPY07_RS17535	COG1301	dicarboxylic acid transport
GPY07_RS17560	COG2814	Major facilitator Superfamily
GPY07_RS17565	COG0583	DNA-binding transcription factor activity
GPY07_RS17570	COG5001	Diguanylate cyclase
GPY07_RS17570	COG3300	MHYT domain
GPY07_RS17575	COG0739	heme binding
GPY07_RS17585	COG0659	secondary active sulfate transmembrane transporter activity
GPY07_RS17605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY07_RS17610	COG0581	inorganic phosphate transmembrane transporter activity
GPY07_RS17615	COG0573	inorganic phosphate transmembrane transporter activity
GPY07_RS17620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY07_RS17650	COG1770	oligopeptidase
GPY07_RS17655	COG0513	Belongs to the DEAD box helicase family
GPY07_RS17665	COG1376	ErfK ybiS ycfS ynhG family protein
GPY07_RS17665	COG1388	LysM domain
GPY07_RS17670	COG0415	Belongs to the DNA photolyase family
GPY07_RS17680	COG3272	Protein of unknown function (DUF1722)
GPY07_RS17685	COG0813	purine-nucleoside phosphorylase activity
GPY07_RS17700	COG3706	GGDEF domain
GPY07_RS17710	COG1566	PFAM secretion protein HlyD family protein
GPY07_RS17730	COG0786	glutamate:sodium symporter activity
GPY07_RS17745	COG1999	signal sequence binding
GPY07_RS17755	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GPY07_RS17760	COG0671	phosphoesterase, PA-phosphatase related
GPY07_RS17805	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPY07_RS17810	COG0471	metal ion transport
GPY07_RS17845	COG3501	Rhs element vgr protein
GPY07_RS17855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GPY07_RS17860	COG1640	4-alpha-glucanotransferase
GPY07_RS17865	COG0058	SHG alpha-glucan phosphorylase activity
GPY07_RS17870	COG2909	trisaccharide binding
GPY07_RS17890	COG2084	Dehydrogenase
GPY07_RS17895	COG0217	transcriptional regulatory protein
GPY07_RS17930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY07_RS17935	COG1444	tRNA N-acetyltransferase activity
GPY07_RS17965	COG0745	RESPONSE REGULATOR receiver
GPY07_RS17970	COG0642	Histidine kinase
GPY07_RS17975	COG2194	sulfuric ester hydrolase activity
GPY07_RS17985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY07_RS17990	COG0601	transmembrane transport
GPY07_RS18010	COG2198	Histidine kinase
GPY07_RS18010	COG0643	Histidine kinase
GPY07_RS18015	COG0835	chemotaxis
GPY07_RS18020	COG0835	chemotaxis
GPY07_RS18025	COG0840	transmembrane signaling receptor activity
GPY07_RS18030	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPY07_RS18035	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GPY07_RS18055	COG0745	RESPONSE REGULATOR receiver
GPY07_RS18085	COG0259	pyridoxamine-phosphate oxidase activity
GPY07_RS18095	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GPY07_RS18120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY07_RS18150	COG1982	Orn Lys Arg decarboxylase major
GPY07_RS18155	COG0531	amino acid
GPY07_RS18165	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY07_RS18170	COG1901	pseudouridine methyltransferase
GPY07_RS18180	COG4221	oxidoreductase activity
GPY07_RS18185	COG0840	transmembrane signaling receptor activity
GPY07_RS18195	COG2910	NAD(P)H-binding
GPY07_RS18225	COG0673	inositol 2-dehydrogenase activity
GPY07_RS18230	COG3722	fumarate hydratase activity
GPY07_RS18235	COG0246	Mannitol dehydrogenase
GPY07_RS18240	COG2213	PTS system mannitol-specific
GPY07_RS18240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY07_RS18250	COG0739	heme binding
GPY07_RS18260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY07_RS18265	COG4597	amino acid ABC transporter
GPY07_RS18270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY07_RS18280	COG1126	abc transporter atp-binding protein
GPY07_RS18285	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY07_RS18295	COG0840	transmembrane signaling receptor activity
GPY07_RS18310	COG0840	transmembrane signaling receptor activity
GPY07_RS18325	COG4580	involved in the transport of maltose and maltodextrins
GPY07_RS18340	COG0363	glucosamine-6-phosphate deaminase activity
GPY07_RS18365	COG2259	Doxx family
GPY07_RS18370	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GPY07_RS18375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPY07_RS18385	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GPY07_RS18390	COG3366	ferrous iron transmembrane transporter activity
GPY07_RS18395	COG0700	Nucleoside recognition
GPY07_RS18405	COG0697	spore germination
GPY07_RS18410	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPY07_RS18415	COG1764	response to oxidative stress
GPY07_RS18420	COG1846	Transcriptional regulator
GPY07_RS18440	COG2207	Transcriptional regulator
GPY07_RS18445	COG1280	lysine exporter protein (LysE YggA)
GPY07_RS18455	COG1902	pentaerythritol trinitrate reductase activity
GPY07_RS18465	COG1132	(ABC) transporter
GPY07_RS18475	COG1902	pentaerythritol trinitrate reductase activity
GPY07_RS18485	COG0583	DNA-binding transcription factor activity
GPY07_RS18490	COG0513	Belongs to the DEAD box helicase family
GPY07_RS18500	COG0840	transmembrane signaling receptor activity
GPY07_RS18510	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GPY07_RS18520	COG1304	FMN binding
GPY07_RS18525	COG1620	l-lactate permease
GPY07_RS18530	COG0583	DNA-binding transcription factor activity
GPY07_RS18555	COG4172	Belongs to the ABC transporter superfamily
GPY07_RS18565	COG1067	ATP-dependent peptidase activity
GPY07_RS18570	COG0840	transmembrane signaling receptor activity
GPY07_RS18580	COG2211	Major facilitator Superfamily
GPY07_RS18590	COG3123	guanosine phosphorylase activity
GPY07_RS18595	COG1741	Belongs to the pirin family
GPY07_RS18605	COG5001	Diguanylate cyclase
GPY07_RS18610	COG0583	DNA-binding transcription factor activity
GPY07_RS18645	COG3706	GGDEF domain
GPY07_RS18650	COG1846	Transcriptional regulator
GPY07_RS18655	COG0835	chemotaxis
GPY07_RS18655	COG0784	Response regulator, receiver
GPY07_RS18660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY07_RS18665	COG2197	response regulator
GPY07_RS18670	COG0393	Putative heavy-metal-binding
GPY07_RS18685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY07_RS18690	COG3842	ATPase activity
GPY07_RS18700	COG1175	transmembrane transport
GPY07_RS18705	COG3833	ABC-type maltose transport systems, permease component
GPY07_RS18720	COG1349	DNA-binding transcription factor activity
GPY07_RS18725	COG3706	GGDEF domain
GPY07_RS18735	COG2207	Transcriptional regulator
GPY07_RS18735	COG4753	response regulator
GPY07_RS18750	COG1278	Cold shock
GPY07_RS18755	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPY07_RS18760	COG2354	Protein conserved in bacteria
GPY07_RS18765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY07_RS18775	COG3152	Membrane
GPY07_RS18785	COG0418	dihydroorotase activity
GPY07_RS18790	COG3217	Mosc domain protein beta barrel domain protein
GPY07_RS18790	COG0633	Ferredoxin
GPY07_RS18790	COG0633	Ferredoxin
GPY07_RS18790	COG3217	Mosc domain protein beta barrel domain protein
GPY07_RS18825	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GPY07_RS18830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY07_RS18835	COG4558	Periplasmic binding protein
GPY07_RS18840	COG0848	biopolymer transport protein
GPY07_RS18845	COG0811	peptide transport
GPY07_RS18850	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GPY07_RS18860	COG3721	Heme iron utilization protein
GPY07_RS18865	COG0748	coenzyme F420 binding
GPY07_RS18875	COG3835	regulator
GPY07_RS18880	COG2610	gluconate transmembrane transporter activity
GPY07_RS18885	COG1929	Belongs to the glycerate kinase type-1 family
GPY07_RS18910	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPY07_RS18915	COG0363	glucosamine-6-phosphate deaminase activity
GPY07_RS18920	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPY07_RS18930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPY07_RS18950	COG0346	lactoylglutathione lyase activity
GPY07_RS18975	COG1063	alcohol dehydrogenase
GPY07_RS19020	COG0583	DNA-binding transcription factor activity
GPY07_RS19025	COG3048	D-serine ammonia-lyase activity
GPY07_RS19040	COG1294	oxidase, subunit
GPY07_RS19045	COG1271	oxidase subunit
GPY07_RS19050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY07_RS19055	COG1686	Belongs to the peptidase S11 family
GPY07_RS19065	COG3047	cAMP biosynthetic process
GPY07_RS19075	COG3227	Zinc metalloprotease (Elastase)
GPY07_RS19085	COG2267	carboxylic ester hydrolase activity
GPY07_RS19090	COG2067	long-chain fatty acid transport protein
GPY07_RS19100	COG0366	Alpha amylase catalytic
GPY07_RS19105	COG4989	oxidoreductase activity
GPY07_RS19120	COG1136	(ABC) transporter
GPY07_RS19125	COG1136	(ABC) transporter
GPY07_RS19125	COG0577	efflux transmembrane transporter activity
GPY07_RS19140	COG3275	phosphorelay sensor kinase activity
GPY07_RS19145	COG3279	Response regulator of the LytR AlgR family
GPY07_RS19155	COG3706	GGDEF domain
GPY07_RS19160	COG0531	amino acid
GPY07_RS19185	COG1765	OsmC-like protein
GPY07_RS19190	COG1253	flavin adenine dinucleotide binding
GPY07_RS19195	COG2171	N-acyltransferase activity
GPY07_RS19210	COG0583	DNA-binding transcription factor activity
GPY07_RS19215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY07_RS19230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY07_RS19235	COG3186	Phenylalanine-4-hydroxylase
GPY07_RS19240	COG2154	pterin-4-alpha-carbinolamine dehydratase
GPY07_RS19245	COG0456	acetyltransferase
GPY07_RS19250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPY07_RS19255	COG0662	Cupin 2, conserved barrel domain protein
GPY07_RS19260	COG0527	aspartate kinase activity
GPY07_RS19270	COG0459	protein refolding
GPY07_RS19275	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPY07_RS19280	COG2239	Acts as a magnesium transporter
GPY07_RS19295	COG1166	arginine decarboxylase activity
GPY07_RS19300	COG0010	Belongs to the arginase family
GPY07_RS19310	COG3227	Zinc metalloprotease (Elastase)
GPY07_RS19315	COG3397	chitin binding
GPY07_RS19320	COG3046	protein related to deoxyribodipyrimidine photolyase
GPY07_RS19330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY07_RS19340	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GPY07_RS19345	COG0513	Belongs to the DEAD box helicase family