locus-tag	class	description
FORC73_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FORC73_RS00010	COG0592	DNA-directed DNA polymerase activity
FORC73_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FORC73_RS00020	COG0187	DNA topoisomerase II activity
FORC73_RS00035	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC73_RS00040	COG3977	Valine--pyruvate aminotransferase
FORC73_RS00045	COG0751	glycine-tRNA ligase activity
FORC73_RS00050	COG0752	glycyl-tRNA synthetase alpha subunit
FORC73_RS00055	COG2119	membrane
FORC73_RS00070	COG0425	Belongs to the sulfur carrier protein TusA family
FORC73_RS00080	COG3385	transposase activity
FORC73_RS00085	COG0604	alcohol dehydrogenase
FORC73_RS00095	COG0129	dihydroxy-acid dehydratase activity
FORC73_RS00100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC73_RS00115	COG0606	chelatase, subunit chli
FORC73_RS00120	COG0204	Acyl-transferase
FORC73_RS00125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC73_RS00130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC73_RS00140	COG3084	Protein conserved in bacteria
FORC73_RS00150	COG4326	sporulation control protein
FORC73_RS00155	COG1272	protein, Hemolysin III
FORC73_RS00165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC73_RS00170	COG0569	domain protein
FORC73_RS00175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC73_RS00175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC73_RS00180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC73_RS00185	COG0242	peptide deformylase activity
FORC73_RS00190	COG1652	LysM domain
FORC73_RS00195	COG0758	DNA mediated transformation
FORC73_RS00200	COG2922	Belongs to the Smg family
FORC73_RS00205	COG0551	DNA topoisomerase type I activity
FORC73_RS00210	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FORC73_RS00215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC73_RS00220	COG0009	L-threonylcarbamoyladenylate synthase
FORC73_RS00225	COG0408	coproporphyrinogen oxidase activity
FORC73_RS00230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORC73_RS00240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC73_RS00280	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FORC73_RS00285	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FORC73_RS00295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC73_RS00300	COG2104	thiamine diphosphate biosynthetic process
FORC73_RS00305	COG2022	thiamine diphosphate biosynthetic process
FORC73_RS00310	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FORC73_RS00315	COG0006	proline dipeptidase activity
FORC73_RS00315	COG0006	proline dipeptidase activity
FORC73_RS00335	COG1522	sequence-specific DNA binding
FORC73_RS00340	COG5001	Diguanylate cyclase
FORC73_RS00340	COG5002	protein histidine kinase activity
FORC73_RS00360	COG0589	response to stress
FORC73_RS00370	COG1528	Iron-storage protein
FORC73_RS00380	COG2081	HI0933 family
FORC73_RS00390	COG1322	Protein conserved in bacteria
FORC73_RS00395	COG2226	methyltransferase
FORC73_RS00410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC73_RS00415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC73_RS00420	COG0805	protein transport
FORC73_RS00425	COG1858	cytochrome C peroxidase
FORC73_RS00430	COG0534	Mate efflux family protein
FORC73_RS00440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC73_RS00450	COG2937	Belongs to the GPAT DAPAT family
FORC73_RS00455	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FORC73_RS00460	COG3161	chorismate lyase activity
FORC73_RS00470	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC73_RS00485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC73_RS00495	COG0084	hydrolase, TatD family'
FORC73_RS00510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC73_RS00510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC73_RS00530	COG3078	GTPase activator activity
FORC73_RS00545	COG3071	HemY protein
FORC73_RS00550	COG2959	enzyme of heme biosynthesis
FORC73_RS00555	COG1587	Uroporphyrinogen-III synthase
FORC73_RS00560	COG0181	hydroxymethylbilane synthase activity
FORC73_RS00575	COG1965	Belongs to the frataxin family
FORC73_RS00585	COG0019	diaminopimelate decarboxylase activity
FORC73_RS00590	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FORC73_RS00600	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FORC73_RS00605	COG1011	Hydrolase
FORC73_RS00610	COG2200	EAL domain
FORC73_RS00610	COG2199	diguanylate cyclase activity
FORC73_RS00610	COG3287	FIST C domain
FORC73_RS00630	COG0561	phosphatase activity
FORC73_RS00635	COG2267	carboxylic ester hydrolase activity
FORC73_RS00640	COG1280	lysine exporter protein (LysE YggA)
FORC73_RS00645	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC73_RS00650	COG0783	Belongs to the Dps family
FORC73_RS00690	COG0742	ribosomal rna small subunit methyltransferase
FORC73_RS00695	COG0552	protein localization to endoplasmic reticulum
FORC73_RS00700	COG2884	Cell division ATP-binding protein ftsE
FORC73_RS00705	COG2177	Part of the ABC transporter FtsEX involved in
FORC73_RS00710	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC73_RS00715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC73_RS00735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC73_RS00740	COG4206	TonB-dependent receptor
FORC73_RS00750	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FORC73_RS00820	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FORC73_RS00825	COG3300	MHYT domain
FORC73_RS00825	COG5001	Diguanylate cyclase
FORC73_RS00835	COG3852	Histidine kinase
FORC73_RS00845	COG0174	glutamine synthetase
FORC73_RS00855	COG1217	gtp-binding protein TYPA
FORC73_RS00860	COG1660	Displays ATPase and GTPase activities
FORC73_RS00865	COG1295	ribonuclease BN
FORC73_RS00870	COG1490	D-aminoacyl-tRNA deacylase activity
FORC73_RS00875	COG0456	acetyltransferase
FORC73_RS00885	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FORC73_RS00890	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FORC73_RS00895	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC73_RS00900	COG3031	protein transport across the cell outer membrane
FORC73_RS00910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC73_RS00915	COG1459	type II secretion system
FORC73_RS00920	COG2165	general secretion pathway protein
FORC73_RS00925	COG2165	general secretion pathway protein
FORC73_RS00930	COG2165	general secretion pathway protein
FORC73_RS00935	COG4795	General secretion pathway protein
FORC73_RS00940	COG3156	type II secretion system protein K
FORC73_RS00945	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC73_RS00950	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC73_RS00960	COG1218	3'(2'),5'-bisphosphate nucleotidase
FORC73_RS00965	COG0494	nUDIX hydrolase
FORC73_RS00975	COG1040	competence protein
FORC73_RS00980	COG0596	Alpha beta hydrolase
FORC73_RS00990	COG2183	response to ionizing radiation
FORC73_RS00995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC73_RS01020	COG1129	ABC transporter
FORC73_RS01025	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC73_RS01030	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC73_RS01050	COG2233	PERMEase
FORC73_RS01055	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC73_RS01060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC73_RS01065	COG1758	RNA polymerase activity
FORC73_RS01070	COG0194	GDP metabolic process
FORC73_RS01075	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FORC73_RS01080	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC73_RS01100	COG4232	protein-disulfide reductase activity
FORC73_RS01110	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC73_RS01115	COG1027	Aspartate ammonia-lyase
FORC73_RS01120	COG3706	GGDEF domain
FORC73_RS01125	COG3030	protein affecting phage T7 exclusion by the F plasmid
FORC73_RS01130	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC73_RS01140	COG2205	protein histidine kinase activity
FORC73_RS01145	COG0745	RESPONSE REGULATOR receiver
FORC73_RS01155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC73_RS01160	COG0205	6-phosphofructokinase activity
FORC73_RS01165	COG1494	fructose-1,6-bisphosphatase
FORC73_RS01170	COG3074	FtsZ-dependent cytokinesis
FORC73_RS01175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC73_RS01180	COG0460	homoserine dehydrogenase
FORC73_RS01180	COG0527	aspartate kinase activity
FORC73_RS01185	COG0626	cystathionine gamma-synthase activity
FORC73_RS01190	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FORC73_RS01195	COG0281	malic enzyme
FORC73_RS01200	COG0254	rRNA binding
FORC73_RS01205	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC73_RS01210	COG1609	Transcriptional regulator
FORC73_RS01215	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC73_RS01220	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FORC73_RS01225	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FORC73_RS01230	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC73_RS01235	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC73_RS01240	COG0534	Mate efflux family protein
FORC73_RS01245	COG0149	triose-phosphate isomerase activity
FORC73_RS01275	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC73_RS01280	COG0459	protein refolding
FORC73_RS01285	COG3344	reverse transcriptase
FORC73_RS01300	COG1509	lysine 2,3-aminomutase activity
FORC73_RS01305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC73_RS01315	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC73_RS01320	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC73_RS01325	COG1053	succinate dehydrogenase
FORC73_RS01330	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FORC73_RS01335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC73_RS01340	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FORC73_RS01345	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FORC73_RS01350	COG1045	serine acetyltransferase
FORC73_RS01360	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FORC73_RS01365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC73_RS01370	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FORC73_RS01375	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC73_RS01380	COG0137	argininosuccinate synthase activity
FORC73_RS01390	COG0165	Argininosuccinate lyase
FORC73_RS01400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC73_RS01405	COG0678	peroxiredoxin activity
FORC73_RS01405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC73_RS01415	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC73_RS01445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FORC73_RS01450	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FORC73_RS01460	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FORC73_RS01465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC73_RS01470	COG0546	phosphoglycolate phosphatase activity
FORC73_RS01475	COG0180	Tryptophanyl-tRNA synthetase
FORC73_RS01490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC73_RS01500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC73_RS01520	COG3385	transposase activity
FORC73_RS01530	COG3954	Phosphoribulokinase
FORC73_RS01540	COG0429	hydrolase of the alpha beta-hydrolase fold
FORC73_RS01550	COG0488	(ABC) transporter
FORC73_RS01555	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC73_RS01570	COG1047	Peptidyl-prolyl cis-trans
FORC73_RS01580	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC73_RS01590	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FORC73_RS01600	COG0557	exoribonuclease II activity
FORC73_RS01605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC73_RS01610	COG0051	transcription antitermination factor activity, RNA binding
FORC73_RS01615	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FORC73_RS01620	COG0088	Forms part of the polypeptide exit tunnel
FORC73_RS01625	COG0089	rRNA binding
FORC73_RS01630	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FORC73_RS01635	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FORC73_RS01640	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FORC73_RS01645	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FORC73_RS01650	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FORC73_RS01655	COG0255	Belongs to the universal ribosomal protein uL29 family
FORC73_RS01660	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FORC73_RS01665	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FORC73_RS01670	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FORC73_RS01675	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FORC73_RS01680	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FORC73_RS01685	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FORC73_RS01695	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FORC73_RS01700	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FORC73_RS01705	COG1841	ribosomal large subunit assembly
FORC73_RS01715	COG0201	protein transport
FORC73_RS01720	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC73_RS01725	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FORC73_RS01730	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FORC73_RS01735	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FORC73_RS01740	COG0202	RNA polymerase activity
FORC73_RS01745	COG0203	ribosomal protein L17
FORC73_RS01755	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC73_RS01760	COG3061	Opacity-associated protein A
FORC73_RS01760	COG3266	domain, Protein
FORC73_RS01765	COG0697	spore germination
FORC73_RS01770	COG2153	protein acetylation
FORC73_RS01775	COG0513	Belongs to the DEAD box helicase family
FORC73_RS01785	COG0737	Belongs to the 5'-nucleotidase family
FORC73_RS01790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC73_RS01790	COG1648	precorrin-2 dehydrogenase activity
FORC73_RS01795	COG0175	sulfate reduction
FORC73_RS01800	COG2895	sulfate adenylyltransferase (ATP) activity
FORC73_RS01805	COG0529	Catalyzes the synthesis of activated sulfate
FORC73_RS01825	COG0577	efflux transmembrane transporter activity
FORC73_RS01825	COG1136	(ABC) transporter
FORC73_RS01840	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC73_RS01845	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC73_RS01850	COG0729	surface antigen
FORC73_RS01860	COG2105	PFAM AIG2 family protein
FORC73_RS01865	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FORC73_RS01880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC73_RS01885	COG0163	prenyltransferase activity
FORC73_RS01895	COG1178	ABC-type Fe3 transport system permease component
FORC73_RS01900	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FORC73_RS01905	COG3028	Belongs to the UPF0307 family
FORC73_RS01910	COG0312	modulator of DNA gyrase
FORC73_RS01915	COG3385	transposase activity
FORC73_RS01920	COG2239	Acts as a magnesium transporter
FORC73_RS01925	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC73_RS01930	COG1660	Displays ATPase and GTPase activities
FORC73_RS01935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC73_RS01940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC73_RS01950	COG1137	ATPase activity
FORC73_RS01955	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FORC73_RS01970	COG0517	IMP dehydrogenase activity
FORC73_RS01970	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORC73_RS01985	COG1127	ABC transporter
FORC73_RS01990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC73_RS01995	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC73_RS02000	COG2854	intermembrane phospholipid transfer
FORC73_RS02010	COG5007	Belongs to the BolA IbaG family
FORC73_RS02015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FORC73_RS02025	COG0251	oxidation-reduction process
FORC73_RS02035	COG0540	Belongs to the ATCase OTCase family
FORC73_RS02045	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC73_RS02055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC73_RS02060	COG0564	pseudouridine synthase activity
FORC73_RS02065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC73_RS02070	COG0525	valine-tRNA ligase activity
FORC73_RS02075	COG2927	DNA polymerase III (CHI subunit)
FORC73_RS02080	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC73_RS02085	COG0795	lipopolysaccharide-transporting ATPase activity
FORC73_RS02090	COG0795	lipopolysaccharide-transporting ATPase activity
FORC73_RS02105	COG3437	response regulator, receiver
FORC73_RS02150	COG0066	3-isopropylmalate dehydratase activity
FORC73_RS02155	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FORC73_RS02160	COG0473	3-isopropylmalate dehydrogenase activity
FORC73_RS02185	COG0583	DNA-binding transcription factor activity
FORC73_RS02190	COG1022	Amp-dependent synthetase and ligase
FORC73_RS02195	COG0028	Belongs to the TPP enzyme family
FORC73_RS02200	COG0440	acetolactate synthase activity
FORC73_RS02205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC73_RS02210	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FORC73_RS02215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC73_RS02225	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FORC73_RS02230	COG3079	Belongs to the UPF0149 family
FORC73_RS02235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC73_RS02240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC73_RS02255	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FORC73_RS02265	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC73_RS02275	COG1595	DNA-templated transcription, initiation
FORC73_RS02290	COG3086	response to oxidative stress
FORC73_RS02295	COG0481	GTPase activity
FORC73_RS02305	COG0571	ribonuclease III activity
FORC73_RS02310	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC73_RS02315	COG1381	Involved in DNA repair and RecF pathway recombination
FORC73_RS02320	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FORC73_RS02325	COG0736	holo-[acyl-carrier-protein] synthase activity
FORC73_RS02360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC73_RS02365	COG3956	TIGRFAM MazG family protein
FORC73_RS02370	COG0504	CTP synthase activity
FORC73_RS02375	COG0148	phosphopyruvate hydratase activity
FORC73_RS02385	COG3409	Peptidoglycan-binding domain 1 protein
FORC73_RS02385	COG3267	Type II secretory pathway component ExeA
FORC73_RS02395	COG4991	sh3 domain protein
FORC73_RS02400	COG0306	phosphate transporter
FORC73_RS02405	COG1392	Phosphate transport regulator
FORC73_RS02410	COG3025	triphosphatase activity
FORC73_RS02415	COG0840	transmembrane signaling receptor activity
FORC73_RS02420	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FORC73_RS02425	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FORC73_RS02425	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FORC73_RS02430	COG1538	Outer membrane efflux protein
FORC73_RS02435	COG0494	nUDIX hydrolase
FORC73_RS02440	COG3151	Protein conserved in bacteria
FORC73_RS02450	COG3150	esterase
FORC73_RS02455	COG0187	DNA topoisomerase II activity
FORC73_RS02460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC73_RS02470	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FORC73_RS02475	COG0237	dephospho-CoA kinase activity
FORC73_RS02485	COG1459	type II secretion system
FORC73_RS02490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC73_RS02515	COG0716	FMN binding
FORC73_RS02520	COG4974	Belongs to the 'phage' integrase family
FORC73_RS02525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC73_RS02530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC73_RS02535	COG0737	Belongs to the 5'-nucleotidase family
FORC73_RS02545	COG2186	Transcriptional regulator
FORC73_RS02550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FORC73_RS02555	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC73_RS02560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC73_RS02575	COG3116	cell division
FORC73_RS02580	COG0768	penicillin binding
FORC73_RS02585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FORC73_RS02590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC73_RS02600	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FORC73_RS02605	COG0772	Belongs to the SEDS family
FORC73_RS02610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FORC73_RS02615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC73_RS02620	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FORC73_RS02625	COG0849	cell division
FORC73_RS02630	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC73_RS02635	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FORC73_RS02645	COG0653	protein targeting
FORC73_RS02650	COG0494	nUDIX hydrolase
FORC73_RS02655	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FORC73_RS02665	COG0505	Belongs to the CarA family
FORC73_RS02670	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FORC73_RS02705	COG0730	response to heat
FORC73_RS02710	COG0583	DNA-binding transcription factor activity
FORC73_RS02715	COG2860	membrane
FORC73_RS02720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC73_RS02730	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC73_RS02740	COG0493	'glutamate synthase
FORC73_RS02745	COG0069	glutamate synthase activity
FORC73_RS02745	COG0070	glutamate synthase
FORC73_RS02745	COG0067	glutamate synthase
FORC73_RS02755	COG0067	glutamate synthase
FORC73_RS02755	COG0069	glutamate synthase activity
FORC73_RS02755	COG0070	glutamate synthase
FORC73_RS02760	COG1242	4 iron, 4 sulfur cluster binding
FORC73_RS02765	COG2203	Gaf domain
FORC73_RS02765	COG5001	Diguanylate cyclase
FORC73_RS02765	COG4251	negative regulation of phosphorylation
FORC73_RS02765	COG3706	GGDEF domain
FORC73_RS02770	COG2198	Histidine kinase
FORC73_RS02770	COG0784	Response regulator, receiver
FORC73_RS02770	COG5002	protein histidine kinase activity
FORC73_RS02775	COG0745	RESPONSE REGULATOR receiver
FORC73_RS02785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC73_RS02805	COG0083	homoserine kinase activity
FORC73_RS02810	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FORC73_RS02815	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FORC73_RS02820	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FORC73_RS02825	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FORC73_RS02840	COG1115	amino acid carrier protein
FORC73_RS02845	COG3022	response to hydroperoxide
FORC73_RS02850	COG0084	hydrolase, TatD family'
FORC73_RS02855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC73_RS02870	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FORC73_RS02875	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC73_RS02880	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FORC73_RS02885	COG0813	purine-nucleoside phosphorylase activity
FORC73_RS02890	COG3385	transposase activity
FORC73_RS02900	COG0560	Phosphoserine phosphatase
FORC73_RS02910	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC73_RS02915	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC73_RS02920	COG1022	Amp-dependent synthetase and ligase
FORC73_RS02935	COG3250	beta-galactosidase activity
FORC73_RS02940	COG1609	Transcriptional regulator
FORC73_RS02945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC73_RS02960	COG0189	ligase activity
FORC73_RS02960	COG0569	domain protein
FORC73_RS02965	COG0456	acetyltransferase
FORC73_RS02975	COG2171	N-acyltransferase activity
FORC73_RS02980	COG3141	response to X-ray
FORC73_RS03000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FORC73_RS03005	COG1074	ATP-dependent DNA helicase activity
FORC73_RS03010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC73_RS03020	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC73_RS03020	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC73_RS03030	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FORC73_RS03035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC73_RS03040	COG2166	iron-sulfur cluster assembly
FORC73_RS03045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC73_RS03050	COG0693	protein deglycase activity
FORC73_RS03055	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC73_RS03060	COG3248	Nucleoside-binding outer membrane protein
FORC73_RS03070	COG1595	DNA-templated transcription, initiation
FORC73_RS03080	COG2211	Major facilitator Superfamily
FORC73_RS03085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC73_RS03095	COG2813	Specifically methylates the guanine in position
FORC73_RS03100	COG0271	Belongs to the BolA IbaG family
FORC73_RS03105	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC73_RS03110	COG1805	sodium ion transport
FORC73_RS03115	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC73_RS03120	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC73_RS03125	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC73_RS03130	COG2871	sodium ion transport
FORC73_RS03135	COG1477	protein flavinylation
FORC73_RS03155	COG3706	GGDEF domain
FORC73_RS03160	COG0733	neurotransmitter:sodium symporter activity
FORC73_RS03165	COG3385	transposase activity
FORC73_RS03175	COG0189	ligase activity
FORC73_RS03180	COG0189	ligase activity
FORC73_RS03180	COG4067	protein conserved in archaea
FORC73_RS03185	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC73_RS03190	COG2252	PERMEase
FORC73_RS03195	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FORC73_RS03200	COG1073	alpha beta
FORC73_RS03210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FORC73_RS03215	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FORC73_RS03220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FORC73_RS03225	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC73_RS03225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC73_RS03240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FORC73_RS03245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC73_RS03250	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FORC73_RS03255	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC73_RS03270	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FORC73_RS03275	COG0024	Methionine aminopeptidase
FORC73_RS03280	COG0052	Belongs to the universal ribosomal protein uS2 family
FORC73_RS03285	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FORC73_RS03290	COG0528	UMP kinase activity
FORC73_RS03295	COG0233	cytoplasmic translational termination
FORC73_RS03300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FORC73_RS03305	COG0575	Belongs to the CDS family
FORC73_RS03310	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FORC73_RS03315	COG0750	zinc metalloprotease
FORC73_RS03325	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FORC73_RS03330	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC73_RS03335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC73_RS03340	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC73_RS03345	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC73_RS03350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FORC73_RS03355	COG0587	DNA-directed DNA polymerase activity
FORC73_RS03360	COG0825	malonyl-CoA metabolic process
FORC73_RS03365	COG0037	tRNA processing
FORC73_RS03375	COG3479	Phenolic acid decarboxylase
FORC73_RS03380	COG0347	Belongs to the P(II) protein family
FORC73_RS03385	COG3021	interspecies interaction between organisms
FORC73_RS03390	COG1388	LysM domain
FORC73_RS03390	COG0741	lytic transglycosylase activity
FORC73_RS03395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC73_RS03400	COG2226	methyltransferase
FORC73_RS03405	COG0328	RNA-DNA hybrid ribonuclease activity
FORC73_RS03430	COG3220	belongs to the UPF0276 family
FORC73_RS03450	COG1294	oxidase, subunit
FORC73_RS03460	COG1960	acyl-CoA dehydrogenase activity
FORC73_RS03465	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC73_RS03470	COG0121	glutamine amidotransferase
FORC73_RS03475	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC73_RS03480	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FORC73_RS03485	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FORC73_RS03495	COG1187	pseudouridine synthase activity
FORC73_RS03500	COG2840	Smr protein MutS2
FORC73_RS03515	COG3735	TraB family
FORC73_RS03530	COG2217	Heavy metal translocating P-type atpase
FORC73_RS03530	COG2608	mercury ion transmembrane transporter activity
FORC73_RS03535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC73_RS03550	COG4774	siderophore transport
FORC73_RS03550	COG1629	transport
FORC73_RS03555	COG2375	cellular response to nickel ion
FORC73_RS03560	COG2226	methyltransferase
FORC73_RS03560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FORC73_RS03560	COG3433	isochorismatase activity
FORC73_RS03595	COG0784	Response regulator, receiver
FORC73_RS03595	COG0835	chemotaxis
FORC73_RS03600	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC73_RS03605	COG1815	bacterial-type flagellum-dependent cell motility
FORC73_RS03620	COG1749	Flagellar hook protein flgE
FORC73_RS03625	COG4787	bacterial-type flagellum-dependent cell motility
FORC73_RS03635	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FORC73_RS03640	COG1706	bacterial-type flagellum-dependent cell motility
FORC73_RS03645	COG1705	Flagellar rod assembly protein muramidase FlgJ
FORC73_RS03645	COG3951	Flagellar rod assembly protein muramidase FlgJ
FORC73_RS03660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC73_RS03665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC73_RS03750	COG0012	GTP binding
FORC73_RS03755	COG0193	aminoacyl-tRNA hydrolase activity
FORC73_RS03760	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FORC73_RS03770	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FORC73_RS03775	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FORC73_RS03780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FORC73_RS03785	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC73_RS03795	COG2912	Transglutaminase-like superfamily
FORC73_RS03800	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FORC73_RS03805	COG0737	Belongs to the 5'-nucleotidase family
FORC73_RS03810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FORC73_RS03815	COG2233	PERMEase
FORC73_RS03835	COG1393	Belongs to the ArsC family
FORC73_RS03840	COG4783	chaperone-mediated protein folding
FORC73_RS03860	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC73_RS03875	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FORC73_RS03885	COG1876	peptidase activity
FORC73_RS03895	COG1393	Belongs to the ArsC family
FORC73_RS03915	COG2837	iron assimilation
FORC73_RS03920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC73_RS03925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC73_RS03930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC73_RS03935	COG1334	flagellar protein FlaG
FORC73_RS03940	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FORC73_RS03950	COG1516	flagellar protein fliS
FORC73_RS03970	COG1677	Flagellar hook-basal body complex protein FliE
FORC73_RS03980	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC73_RS03985	COG1317	bacterial-type flagellum organization
FORC73_RS04010	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC73_RS04035	COG1987	bacterial-type flagellum assembly
FORC73_RS04040	COG1684	flagellar biosynthetic protein fliR
FORC73_RS04050	COG2840	Smr protein MutS2
FORC73_RS04055	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC73_RS04065	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FORC73_RS04070	COG2860	membrane
FORC73_RS04075	COG3101	peptidyl-lysine hydroxylation
FORC73_RS04090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC73_RS04090	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC73_RS04095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC73_RS04100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC73_RS04105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC73_RS04110	COG0735	belongs to the Fur family
FORC73_RS04120	COG0583	DNA-binding transcription factor activity
FORC73_RS04130	COG1346	cytolysis
FORC73_RS04145	COG0596	Alpha beta hydrolase
FORC73_RS04150	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FORC73_RS04155	COG0033	Phosphoglucomutase
FORC73_RS04165	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC73_RS04170	COG0372	Belongs to the citrate synthase family
FORC73_RS04175	COG2009	succinate dehydrogenase
FORC73_RS04180	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FORC73_RS04185	COG1053	succinate dehydrogenase
FORC73_RS04195	COG0567	Dehydrogenase, E1 component
FORC73_RS04200	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC73_RS04205	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC73_RS04215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC73_RS04220	COG1121	(ABC) transporter
FORC73_RS04225	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FORC73_RS04230	COG4977	sequence-specific DNA binding
FORC73_RS04240	COG1918	ferrous iron import across plasma membrane
FORC73_RS04260	COG0018	arginyl-trna synthetase
FORC73_RS04275	COG2062	phosphohistidine phosphatase, SixA
FORC73_RS04305	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FORC73_RS04310	COG2198	Histidine kinase
FORC73_RS04310	COG0643	Histidine kinase
FORC73_RS04310	COG0784	Response regulator, receiver
FORC73_RS04315	COG2201	protein-glutamate methylesterase activity
FORC73_RS04320	COG1192	Involved in chromosome partitioning
FORC73_RS04330	COG0835	chemotaxis
FORC73_RS04340	COG4133	protoheme IX ABC transporter activity
FORC73_RS04345	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC73_RS04350	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC73_RS04360	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FORC73_RS04365	COG1138	Cytochrome C-type biogenesis protein
FORC73_RS04370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC73_RS04375	COG4235	cytochrome complex assembly
FORC73_RS04375	COG3088	subunit of a heme lyase
FORC73_RS04385	COG2853	Lipoprotein
FORC73_RS04405	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FORC73_RS04410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC73_RS04415	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC73_RS04435	COG3082	Protein of unknown function (DUF1414)
FORC73_RS04440	COG3081	Nucleoid-associated protein
FORC73_RS04450	COG1757	Na H antiporter
FORC73_RS04455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC73_RS04460	COG2095	MarC family integral membrane protein
FORC73_RS04465	COG1012	belongs to the aldehyde dehydrogenase family
FORC73_RS04465	COG1454	alcohol dehydrogenase
FORC73_RS04480	COG0659	secondary active sulfate transmembrane transporter activity
FORC73_RS04485	COG1530	ribonuclease E activity
FORC73_RS04500	COG0564	pseudouridine synthase activity
FORC73_RS04505	COG0424	maF-like protein
FORC73_RS04510	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC73_RS04515	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FORC73_RS04520	COG0416	fatty acid biosynthetic process
FORC73_RS04525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC73_RS04535	COG1028	Short-chain dehydrogenase reductase Sdr
FORC73_RS04540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC73_RS04545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC73_RS04550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC73_RS04555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC73_RS04560	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FORC73_RS04570	COG0084	hydrolase, TatD family'
FORC73_RS04575	COG1263	PTS System
FORC73_RS04575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC73_RS04585	COG0733	neurotransmitter:sodium symporter activity
FORC73_RS04600	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC73_RS04610	COG1940	carbohydrate kinase activity
FORC73_RS04615	COG0784	Response regulator, receiver
FORC73_RS04615	COG0835	chemotaxis
FORC73_RS04630	COG2226	methyltransferase
FORC73_RS04645	COG0676	glucose-6-phosphate 1-epimerase activity
FORC73_RS04650	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC73_RS04655	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC73_RS04665	COG3139	Protein of unknown function (DUF1315)
FORC73_RS04670	COG0252	asparaginase activity
FORC73_RS04675	COG0616	signal peptide processing
FORC73_RS04680	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC73_RS04680	COG1902	pentaerythritol trinitrate reductase activity
FORC73_RS04685	COG0788	formyltetrahydrofolate deformylase activity
FORC73_RS04700	COG1199	ATP-dependent helicase activity
FORC73_RS04705	COG1214	PFAM Peptidase M22, glycoprotease
FORC73_RS04720	COG0596	Alpha beta hydrolase
FORC73_RS04725	COG0318	PFAM AMP-dependent synthetase and ligase
FORC73_RS04730	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FORC73_RS04745	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FORC73_RS04750	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FORC73_RS04755	COG0436	Aminotransferase
FORC73_RS04760	COG1169	isochorismate synthase
FORC73_RS04765	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FORC73_RS04770	COG0596	Alpha beta hydrolase
FORC73_RS04790	COG3135	benzoate transporter
FORC73_RS04795	COG1396	sequence-specific DNA binding
FORC73_RS04800	COG0840	transmembrane signaling receptor activity
FORC73_RS04815	COG0477	Major facilitator Superfamily
FORC73_RS04835	COG3015	lipoprotein NlpE involved in copper resistance
FORC73_RS04840	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FORC73_RS04845	COG2894	cell division
FORC73_RS04850	COG0850	regulation of cytokinetic process
FORC73_RS04855	COG3100	YcgL domain-containing protein
FORC73_RS04860	COG2951	lytic endotransglycosylase activity
FORC73_RS04870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC73_RS04875	COG3005	denitrification pathway
FORC73_RS04880	COG0243	molybdopterin cofactor binding
FORC73_RS04900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC73_RS04910	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FORC73_RS04950	COG4589	Belongs to the CDS family
FORC73_RS04960	COG3300	MHYT domain
FORC73_RS04960	COG5001	Diguanylate cyclase
FORC73_RS04975	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FORC73_RS04980	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC73_RS04985	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC73_RS04990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC73_RS05000	COG4191	Histidine kinase
FORC73_RS05010	COG0544	peptidyl-prolyl cis-trans isomerase activity
FORC73_RS05020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FORC73_RS05025	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FORC73_RS05030	COG0776	regulation of translation
FORC73_RS05035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC73_RS05040	COG1555	photosystem II stabilization
FORC73_RS05045	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FORC73_RS05050	COG0539	negative regulation of cytoplasmic translation
FORC73_RS05055	COG0776	regulation of translation
FORC73_RS05060	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FORC73_RS05065	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FORC73_RS05075	COG0601	transmembrane transport
FORC73_RS05080	COG4239	(ABC) transporter, permease
FORC73_RS05085	COG0747	negative chemotaxis
FORC73_RS05090	COG0444	Belongs to the ABC transporter superfamily
FORC73_RS05095	COG4608	Belongs to the ABC transporter superfamily
FORC73_RS05120	COG0583	DNA-binding transcription factor activity
FORC73_RS05130	COG0686	Belongs to the AlaDH PNT family
FORC73_RS05140	COG1674	ftsk spoiiie
FORC73_RS05145	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FORC73_RS05150	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC73_RS05155	COG2186	Transcriptional regulator
FORC73_RS05170	COG0537	adenosine 5'-monophosphoramidase activity
FORC73_RS05195	COG3150	esterase
FORC73_RS05200	COG1252	NADH dehydrogenase
FORC73_RS05220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC73_RS05230	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC73_RS05235	COG1136	(ABC) transporter
FORC73_RS05240	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC73_RS05250	COG2333	competence protein COMEC
FORC73_RS05250	COG0658	competence protein
FORC73_RS05255	COG1132	(ABC) transporter
FORC73_RS05260	COG1663	tetraacyldisaccharide 4'-kinase activity
FORC73_RS05265	COG2835	tetraacyldisaccharide 4'-kinase activity
FORC73_RS05270	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORC73_RS05275	COG2719	SpoVR family
FORC73_RS05280	COG2718	Belongs to the UPF0229 family
FORC73_RS05285	COG2766	serine protein kinase
FORC73_RS05290	COG3013	Belongs to the UPF0304 family
FORC73_RS05300	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC73_RS05310	COG0840	transmembrane signaling receptor activity
FORC73_RS05320	COG1882	Formate acetyltransferase
FORC73_RS05345	COG4160	amino acid transport
FORC73_RS05350	COG0708	Exodeoxyribonuclease III
FORC73_RS05355	COG0840	transmembrane signaling receptor activity
FORC73_RS05365	COG3923	Primosomal replication protein n
FORC73_RS05370	COG0730	response to heat
FORC73_RS05375	COG1199	ATP-dependent helicase activity
FORC73_RS05380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC73_RS05385	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC73_RS05390	COG3012	SEC-C Motif Domain Protein
FORC73_RS05395	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC73_RS05400	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC73_RS05405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC73_RS05410	COG0215	cysteine-tRNA ligase activity
FORC73_RS05415	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FORC73_RS05420	COG0632	four-way junction helicase activity
FORC73_RS05430	COG1271	oxidase subunit
FORC73_RS05435	COG1294	oxidase, subunit
FORC73_RS05440	COG4890	Cyd operon protein YbgT
FORC73_RS05445	COG3790	cyd operon protein YbgE
FORC73_RS05450	COG0824	Thioesterase
FORC73_RS05455	COG0811	peptide transport
FORC73_RS05470	COG0823	Involved in the tonB-independent uptake of proteins
FORC73_RS05475	COG2885	chlorophyll binding
FORC73_RS05485	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FORC73_RS05500	COG0784	Response regulator, receiver
FORC73_RS05500	COG5002	protein histidine kinase activity
FORC73_RS05515	COG3335	DDE superfamily endonuclease
FORC73_RS05520	COG1012	belongs to the aldehyde dehydrogenase family
FORC73_RS05525	COG3284	Transcriptional regulator
FORC73_RS05530	COG4628	conserved protein (DUF2132)
FORC73_RS05540	COG0415	Belongs to the DNA photolyase family
FORC73_RS05590	COG2003	Belongs to the UPF0758 family
FORC73_RS05600	COG4409	exo-alpha-(2->6)-sialidase activity
FORC73_RS05605	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC73_RS05610	COG1940	carbohydrate kinase activity
FORC73_RS05625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC73_RS05630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC73_RS05635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC73_RS05640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC73_RS05645	COG1737	Transcriptional regulator
FORC73_RS05650	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC73_RS05655	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC73_RS05665	COG4932	domain protein
FORC73_RS05665	COG5492	domain, Protein
FORC73_RS05685	COG2267	carboxylic ester hydrolase activity
FORC73_RS05810	COG4789	Type iii secretion
FORC73_RS05815	COG4792	protein secretion
FORC73_RS05845	COG3710	Transcriptional regulator
FORC73_RS05860	COG4790	Type iii secretion
FORC73_RS05945	COG0582	viral genome integration into host DNA
FORC73_RS05960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC73_RS05970	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC73_RS05970	COG3008	intermembrane lipid transfer
FORC73_RS05975	COG2995	paraquat-inducible protein a
FORC73_RS05980	COG1309	transcriptional regulator
FORC73_RS05985	COG1012	belongs to the aldehyde dehydrogenase family
FORC73_RS06005	COG1960	acyl-CoA dehydrogenase activity
FORC73_RS06010	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC73_RS06020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FORC73_RS06030	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FORC73_RS06050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC73_RS06055	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC73_RS06060	COG0297	glycogen (starch) synthase activity
FORC73_RS06080	COG3070	regulator of competence-specific genes
FORC73_RS06085	COG1609	Transcriptional regulator
FORC73_RS06095	COG3381	protein complex oligomerization
FORC73_RS06100	COG0745	RESPONSE REGULATOR receiver
FORC73_RS06105	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC73_RS06110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC73_RS06115	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FORC73_RS06120	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FORC73_RS06145	COG1032	radical SAM domain protein
FORC73_RS06155	COG0612	Peptidase, M16
FORC73_RS06170	COG0583	DNA-binding transcription factor activity
FORC73_RS06175	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FORC73_RS06185	COG2350	Protein conserved in bacteria
FORC73_RS06190	COG1607	acyl-coa hydrolase
FORC73_RS06205	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC73_RS06210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC73_RS06225	COG2116	formate transmembrane transporter activity
FORC73_RS06235	COG4459	periplasmic nitrate reductase
FORC73_RS06240	COG3005	denitrification pathway
FORC73_RS06245	COG0243	molybdopterin cofactor binding
FORC73_RS06260	COG1227	inorganic diphosphatase activity
FORC73_RS06275	COG4172	Belongs to the ABC transporter superfamily
FORC73_RS06290	COG4168	peptide transport system, permease
FORC73_RS06300	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC73_RS06305	COG1842	Phage shock protein A
FORC73_RS06320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC73_RS06335	COG3385	transposase activity
FORC73_RS06345	COG2818	Glycosylase
FORC73_RS06350	COG0589	response to stress
FORC73_RS06360	COG0626	cystathionine gamma-synthase activity
FORC73_RS06370	COG0733	neurotransmitter:sodium symporter activity
FORC73_RS06375	COG0564	pseudouridine synthase activity
FORC73_RS06380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC73_RS06385	COG4136	ATPase activity
FORC73_RS06390	COG4135	transport system, permease component
FORC73_RS06395	COG4134	Bacterial extracellular solute-binding protein
FORC73_RS06405	COG3313	Fe-S protein
FORC73_RS06415	COG0842	Transport permease protein
FORC73_RS06420	COG1131	(ABC) transporter
FORC73_RS06425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC73_RS06430	COG0814	amino acid
FORC73_RS06440	COG2239	Acts as a magnesium transporter
FORC73_RS06445	COG2205	protein histidine kinase activity
FORC73_RS06445	COG0784	Response regulator, receiver
FORC73_RS06460	COG4934	collagen metabolic process
FORC73_RS06490	COG0840	transmembrane signaling receptor activity
FORC73_RS06505	COG5001	Diguanylate cyclase
FORC73_RS06505	COG4251	negative regulation of phosphorylation
FORC73_RS06505	COG3706	GGDEF domain
FORC73_RS06505	COG2203	Gaf domain
FORC73_RS06510	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FORC73_RS06535	COG1061	Type III restriction enzyme res subunit
FORC73_RS06540	COG1187	pseudouridine synthase activity
FORC73_RS06545	COG2814	Major facilitator Superfamily
FORC73_RS06555	COG0702	epimerase
FORC73_RS06560	COG0534	Mate efflux family protein
FORC73_RS06565	COG4181	ATPase activity
FORC73_RS06580	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC73_RS06595	COG1748	Saccharopine dehydrogenase
FORC73_RS06610	COG1538	Outer membrane efflux protein
FORC73_RS06630	COG0583	DNA-binding transcription factor activity
FORC73_RS06640	COG1451	nucleotide metabolic process
FORC73_RS06655	COG3063	Type IV pilus biogenesis stability protein PilW
FORC73_RS06660	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FORC73_RS06680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC73_RS06695	COG3290	protein histidine kinase activity
FORC73_RS06700	COG4565	transcriptional regulatory protein
FORC73_RS06710	COG0784	Response regulator, receiver
FORC73_RS06710	COG0835	chemotaxis
FORC73_RS06755	COG1085	galactose-1-phosphate uridylyltransferase
FORC73_RS06760	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FORC73_RS06765	COG2017	converts alpha-aldose to the beta-anomer
FORC73_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
FORC73_RS06785	COG3527	Alpha-acetolactate decarboxylase
FORC73_RS06800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC73_RS06825	COG3097	Belongs to the UPF0267 family
FORC73_RS06850	COG1271	oxidase subunit
FORC73_RS06855	COG1294	oxidase, subunit
FORC73_RS06860	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC73_RS06860	COG1136	(ABC) transporter
FORC73_RS06865	COG0577	efflux transmembrane transporter activity
FORC73_RS06865	COG1136	(ABC) transporter
FORC73_RS06870	COG0577	efflux transmembrane transporter activity
FORC73_RS06870	COG1136	(ABC) transporter
FORC73_RS06900	COG2723	6-phospho-beta-galactosidase activity
FORC73_RS06905	COG1609	Transcriptional regulator
FORC73_RS06910	COG0251	oxidation-reduction process
FORC73_RS06915	COG2731	YhcH YjgK YiaL family protein
FORC73_RS06920	COG0584	glycerophosphoryl diester phosphodiesterase
FORC73_RS06925	COG1349	DNA-binding transcription factor activity
FORC73_RS06930	COG3842	ATPase activity
FORC73_RS06935	COG0395	ABC-type sugar transport system, permease component
FORC73_RS06940	COG1175	transmembrane transport
FORC73_RS06955	COG0811	peptide transport
FORC73_RS06960	COG0811	peptide transport
FORC73_RS06965	COG0848	biopolymer transport protein
FORC73_RS06970	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC73_RS06985	COG1793	dna ligase
FORC73_RS06995	COG0534	Mate efflux family protein
FORC73_RS07005	COG3001	Fructosamine kinase
FORC73_RS07015	COG0791	NLP P60 protein
FORC73_RS07020	COG0840	transmembrane signaling receptor activity
FORC73_RS07030	COG3148	PFAM DTW domain containing protein
FORC73_RS07035	COG1940	carbohydrate kinase activity
FORC73_RS07045	COG0303	'Molybdopterin
FORC73_RS07050	COG0746	molybdenum cofactor guanylyltransferase activity
FORC73_RS07055	COG3842	ATPase activity
FORC73_RS07060	COG4662	Binding-protein-dependent transport system inner membrane component
FORC73_RS07070	COG2204	response regulator
FORC73_RS07075	COG3852	Histidine kinase
FORC73_RS07080	COG0488	(ABC) transporter
FORC73_RS07085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC73_RS07115	COG3383	formate dehydrogenase (NAD+) activity
FORC73_RS07115	COG0243	molybdopterin cofactor binding
FORC73_RS07120	COG0437	4 iron, 4 sulfur cluster binding
FORC73_RS07135	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC73_RS07140	COG1666	GTP binding
FORC73_RS07145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC73_RS07160	COG2996	Protein conserved in bacteria
FORC73_RS07170	COG3008	intermembrane lipid transfer
FORC73_RS07175	COG2995	paraquat-inducible protein a
FORC73_RS07180	COG1132	(ABC) transporter
FORC73_RS07185	COG1956	GAF domain-containing protein
FORC73_RS07190	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FORC73_RS07205	COG0308	aminopeptidase N
FORC73_RS07220	COG0167	dihydroorotate dehydrogenase activity
FORC73_RS07230	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC73_RS07230	COG0116	Belongs to the methyltransferase superfamily
FORC73_RS07240	COG0488	(ABC) transporter
FORC73_RS07255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC73_RS07260	COG1067	ATP-dependent peptidase activity
FORC73_RS07265	COG3120	sequence-specific DNA binding
FORC73_RS07295	COG2994	toxin metabolic process
FORC73_RS07320	COG0784	Response regulator, receiver
FORC73_RS07320	COG2205	protein histidine kinase activity
FORC73_RS07335	COG3278	Belongs to the heme-copper respiratory oxidase family
FORC73_RS07350	COG2010	Cytochrome c
FORC73_RS07360	COG2217	Heavy metal translocating P-type atpase
FORC73_RS07375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC73_RS07380	COG0589	response to stress
FORC73_RS07385	COG0037	tRNA processing
FORC73_RS07405	COG3842	ATPase activity
FORC73_RS07415	COG1177	transmembrane transport
FORC73_RS07425	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC73_RS07440	COG1115	amino acid carrier protein
FORC73_RS07445	COG1280	lysine exporter protein (LysE YggA)
FORC73_RS07465	COG3501	Rhs element vgr protein
FORC73_RS07475	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC73_RS07485	COG2814	Major facilitator Superfamily
FORC73_RS07495	COG1538	Outer membrane efflux protein
FORC73_RS07505	COG0513	Belongs to the DEAD box helicase family
FORC73_RS07530	COG0415	Belongs to the DNA photolyase family
FORC73_RS07535	COG0477	Major facilitator Superfamily
FORC73_RS07540	COG0583	DNA-binding transcription factor activity
FORC73_RS07550	COG0402	S-adenosylhomocysteine deaminase activity
FORC73_RS07555	COG0095	Lipoate-protein ligase
FORC73_RS07560	COG0443	Heat shock 70 kDa protein
FORC73_RS07570	COG1643	Atp-dependent helicase
FORC73_RS07610	COG0443	Heat shock 70 kDa protein
FORC73_RS07615	COG0443	Heat shock 70 kDa protein
FORC73_RS07650	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC73_RS07655	COG0602	queuosine metabolic process
FORC73_RS07660	COG0561	phosphatase activity
FORC73_RS07670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC73_RS07675	COG4597	amino acid ABC transporter
FORC73_RS07680	COG0765	amino acid transport
FORC73_RS07685	COG1126	abc transporter atp-binding protein
FORC73_RS07690	COG0670	Belongs to the BI1 family
FORC73_RS07695	COG2920	part of a sulfur-relay system
FORC73_RS07700	COG1254	Belongs to the acylphosphatase family
FORC73_RS07705	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC73_RS07710	COG3706	GGDEF domain
FORC73_RS07730	COG3437	response regulator, receiver
FORC73_RS07735	COG0625	glutathione transferase activity
FORC73_RS07745	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FORC73_RS07755	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC73_RS07785	COG0372	Belongs to the citrate synthase family
FORC73_RS07790	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC73_RS07850	COG1129	ABC transporter
FORC73_RS07880	COG0745	RESPONSE REGULATOR receiver
FORC73_RS07885	COG2205	protein histidine kinase activity
FORC73_RS07890	COG3713	MltA-interacting MipA family protein
FORC73_RS07895	COG2990	Protein conserved in bacteria
FORC73_RS07905	COG2205	protein histidine kinase activity
FORC73_RS07910	COG0471	metal ion transport
FORC73_RS07920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC73_RS07935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC73_RS07945	COG3768	UPF0283 membrane protein
FORC73_RS07950	COG3106	COG3106 Predicted ATPase
FORC73_RS07965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC73_RS07970	COG0494	nUDIX hydrolase
FORC73_RS07975	COG0814	amino acid
FORC73_RS07980	COG1760	l-serine dehydratase
FORC73_RS07985	COG0720	synthase
FORC73_RS07990	COG0840	transmembrane signaling receptor activity
FORC73_RS07995	COG0017	Asparaginyl-tRNA synthetase
FORC73_RS08000	COG0351	phosphomethylpyrimidine kinase
FORC73_RS08005	COG1448	Aminotransferase
FORC73_RS08020	COG0840	transmembrane signaling receptor activity
FORC73_RS08025	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FORC73_RS08030	COG2943	transferase activity, transferring hexosyl groups
FORC73_RS08035	COG1609	Transcriptional regulator
FORC73_RS08040	COG3394	polysaccharide catabolic process
FORC73_RS08045	COG1486	melibiose metabolic process
FORC73_RS08050	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC73_RS08060	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC73_RS08065	COG0726	polysaccharide deacetylase
FORC73_RS08070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC73_RS08075	COG1846	Transcriptional regulator
FORC73_RS08105	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC73_RS08120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC73_RS08125	COG3108	Peptidase M15
FORC73_RS08160	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC73_RS08170	COG2814	Major facilitator Superfamily
FORC73_RS08180	COG1054	Belongs to the UPF0176 family
FORC73_RS08190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC73_RS08195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC73_RS08200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC73_RS08250	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FORC73_RS08255	COG4139	cobalamin transport
FORC73_RS08260	COG2988	succinylglutamate desuccinylase activity
FORC73_RS08275	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FORC73_RS08280	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FORC73_RS08285	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC73_RS08290	COG1823	symporter activity
FORC73_RS08295	COG2925	Exonuclease
FORC73_RS08300	COG1380	Effector of murein hydrolase LrgA
FORC73_RS08305	COG1346	cytolysis
FORC73_RS08350	COG0776	regulation of translation
FORC73_RS08355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC73_RS08355	COG0072	phenylalanine-tRNA ligase activity
FORC73_RS08360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FORC73_RS08400	COG0322	excinuclease ABC activity
FORC73_RS08405	COG2197	response regulator
FORC73_RS08410	COG0417	DNA replication proofreading
FORC73_RS08415	COG5001	Diguanylate cyclase
FORC73_RS08425	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC73_RS08430	COG3099	Belongs to the UPF0263 family
FORC73_RS08445	COG1228	amidohydrolase
FORC73_RS08450	COG0010	Belongs to the arginase family
FORC73_RS08455	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FORC73_RS08460	COG2986	histidine ammonia-lyase
FORC73_RS08480	COG0247	lactate metabolic process
FORC73_RS08480	COG0277	FAD linked oxidase domain protein
FORC73_RS08495	COG2885	chlorophyll binding
FORC73_RS08515	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FORC73_RS08525	COG0281	malic enzyme
FORC73_RS08535	COG2949	membrane
FORC73_RS08540	COG3706	GGDEF domain
FORC73_RS08545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC73_RS08555	COG0492	ferredoxin-NADP+ reductase activity
FORC73_RS08560	COG4988	ABC transporter
FORC73_RS08565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC73_RS08570	COG1187	pseudouridine synthase activity
FORC73_RS08575	COG0009	L-threonylcarbamoyladenylate synthase
FORC73_RS08580	COG0613	PHP domain protein
FORC73_RS08590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC73_RS08595	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC73_RS08600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC73_RS08605	COG0135	phosphoribosylanthranilate isomerase activity
FORC73_RS08605	COG0134	indole-3-glycerol-phosphate synthase activity
FORC73_RS08610	COG0133	tryptophan synthase activity
FORC73_RS08615	COG0159	tryptophan synthase activity
FORC73_RS08625	COG1435	thymidine kinase activity
FORC73_RS08630	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FORC73_RS08635	COG1801	Protein of unknown function DUF72
FORC73_RS08640	COG4106	trans-aconitate 2-methyltransferase activity
FORC73_RS08645	COG0500	methyltransferase
FORC73_RS08650	COG4067	protein conserved in archaea
FORC73_RS08650	COG0189	ligase activity
FORC73_RS08665	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FORC73_RS08675	COG3852	Histidine kinase
FORC73_RS08690	COG3070	regulator of competence-specific genes
FORC73_RS08700	COG2431	L-lysine efflux transmembrane transporter activity
FORC73_RS08710	COG0076	glutamate decarboxylase activity
FORC73_RS08715	COG1737	Transcriptional regulator
FORC73_RS08720	COG1454	alcohol dehydrogenase
FORC73_RS08720	COG1012	belongs to the aldehyde dehydrogenase family
FORC73_RS08725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC73_RS08730	COG3273	potassium ion transport
FORC73_RS08730	COG2985	domain, Protein
FORC73_RS08735	COG0542	response to heat
FORC73_RS08740	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FORC73_RS08745	COG1278	Cold shock
FORC73_RS08755	COG1187	pseudouridine synthase activity
FORC73_RS08760	COG0140	phosphoribosyl-ATP diphosphatase activity
FORC73_RS08760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FORC73_RS08765	COG0107	imidazoleglycerol-phosphate synthase activity
FORC73_RS08770	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FORC73_RS08775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FORC73_RS08780	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC73_RS08780	COG0131	Imidazoleglycerol-phosphate dehydratase
FORC73_RS08785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC73_RS08790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FORC73_RS08795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FORC73_RS08800	COG1757	Na H antiporter
FORC73_RS08805	COG2916	Histone family protein nucleoid-structuring protein H-NS
FORC73_RS08810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC73_RS08815	COG0482	sulfurtransferase activity
FORC73_RS08820	COG2915	High frequency lysogenization protein hflD homolog
FORC73_RS08825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC73_RS08835	COG2268	Band 7 protein
FORC73_RS08845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FORC73_RS08860	COG0300	oxidoreductase activity
FORC73_RS08870	COG0501	Belongs to the peptidase M48B family
FORC73_RS08880	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FORC73_RS08885	COG2226	methyltransferase
FORC73_RS08890	COG0156	8-amino-7-oxononanoate synthase activity
FORC73_RS08895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FORC73_RS08900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC73_RS08905	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FORC73_RS08910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC73_RS08915	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC73_RS08920	COG0653	protein targeting
FORC73_RS08925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC73_RS08930	COG2203	Gaf domain
FORC73_RS08930	COG2199	diguanylate cyclase activity
FORC73_RS08940	COG4120	Belongs to the binding-protein-dependent transport system permease family
FORC73_RS08950	COG4628	conserved protein (DUF2132)
FORC73_RS08955	COG3092	negative regulation of chromosome organization
FORC73_RS08960	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC73_RS08965	COG0280	phosphate acetyltransferase
FORC73_RS08965	COG0857	belongs to the CobB CobQ family
FORC73_RS08970	COG0435	Glutathione S-transferase
FORC73_RS08975	COG4608	Belongs to the ABC transporter superfamily
FORC73_RS08980	COG0444	Belongs to the ABC transporter superfamily
FORC73_RS08985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC73_RS08990	COG0601	transmembrane transport
FORC73_RS09010	COG2204	response regulator
FORC73_RS09015	COG5001	Diguanylate cyclase
FORC73_RS09015	COG3300	MHYT domain
FORC73_RS09020	COG4191	Histidine kinase
FORC73_RS09025	COG5002	protein histidine kinase activity
FORC73_RS09035	COG2201	protein-glutamate methylesterase activity
FORC73_RS09050	COG0009	L-threonylcarbamoyladenylate synthase
FORC73_RS09070	COG1881	PFAM PEBP family protein
FORC73_RS09105	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC73_RS09110	COG0640	Transcriptional regulator
FORC73_RS09120	COG3706	GGDEF domain
FORC73_RS09140	COG1946	Acyl-CoA thioesterase
FORC73_RS09145	COG1522	sequence-specific DNA binding
FORC73_RS09155	COG0616	signal peptide processing
FORC73_RS09160	COG1028	Short-chain dehydrogenase reductase Sdr
FORC73_RS09185	COG2983	Belongs to the UPF0260 family
FORC73_RS09195	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FORC73_RS09200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FORC73_RS09205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FORC73_RS09210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC73_RS09215	COG2832	Protein of unknown function (DUF454)
FORC73_RS09225	COG0745	RESPONSE REGULATOR receiver
FORC73_RS09230	COG0583	DNA-binding transcription factor activity
FORC73_RS09235	COG0778	Nitroreductase
FORC73_RS09240	COG1024	Enoyl-CoA hydratase
FORC73_RS09240	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC73_RS09245	COG0183	Belongs to the thiolase family
FORC73_RS09265	COG2067	long-chain fatty acid transport protein
FORC73_RS09275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC73_RS09280	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FORC73_RS09285	COG2982	Protein involved in outer membrane biogenesis
FORC73_RS09290	COG0572	uridine kinase
FORC73_RS09300	COG0489	protein tyrosine kinase activity
FORC73_RS09305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC73_RS09305	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC73_RS09315	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FORC73_RS09330	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FORC73_RS09330	COG0617	tRNA 3'-terminal CCA addition
FORC73_RS09330	COG0517	IMP dehydrogenase activity
FORC73_RS09335	COG2199	diguanylate cyclase activity
FORC73_RS09340	COG0314	molybdopterin synthase activity
FORC73_RS09345	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FORC73_RS09350	COG0315	cyclic pyranopterin monophosphate synthase activity
FORC73_RS09355	COG0521	Mo-molybdopterin cofactor biosynthetic process
FORC73_RS09360	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC73_RS09365	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC73_RS09370	COG2198	Histidine kinase
FORC73_RS09375	COG2204	response regulator
FORC73_RS09385	COG0556	nucleotide-excision repair
FORC73_RS09395	COG4657	Part of a membrane complex involved in electron transport
FORC73_RS09400	COG2878	Part of a membrane complex involved in electron transport
FORC73_RS09405	COG4656	Part of a membrane complex involved in electron transport
FORC73_RS09420	COG4660	Part of a membrane complex involved in electron transport
FORC73_RS09425	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC73_RS09430	COG0346	lactoylglutathione lyase activity
FORC73_RS09445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC73_RS09450	COG2056	Na+-H+ antiporter family
FORC73_RS09455	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC73_RS09460	COG1286	toxin biosynthetic process
FORC73_RS09465	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FORC73_RS09470	COG0285	dihydrofolate synthase activity
FORC73_RS09475	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC73_RS09480	COG0101	tRNA pseudouridine synthase activity
FORC73_RS09495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC73_RS09495	COG1263	PTS System
FORC73_RS09495	COG2190	(PTS) system
FORC73_RS09500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC73_RS09505	COG1940	carbohydrate kinase activity
FORC73_RS09505	COG1846	Transcriptional regulator
FORC73_RS09510	COG4651	solute:proton antiporter activity
FORC73_RS09510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC73_RS09515	COG0367	asparagine synthase
FORC73_RS09530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FORC73_RS09535	COG0563	adenylate kinase activity
FORC73_RS09540	COG0326	Molecular chaperone. Has ATPase activity
FORC73_RS09545	COG3710	Transcriptional regulator
FORC73_RS09560	COG0622	Phosphoesterase
FORC73_RS09565	COG1090	epimerase
FORC73_RS09570	COG0300	oxidoreductase activity
FORC73_RS09580	COG3118	belongs to the thioredoxin family
FORC73_RS09590	COG0330	HflC and HflK could
FORC73_RS09595	COG1585	Membrane protein implicated in regulation of membrane protease activity
FORC73_RS09600	COG0789	Transcriptional regulator
FORC73_RS09620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FORC73_RS09625	COG3115	cell septum assembly
FORC73_RS09630	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FORC73_RS09635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC73_RS09645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC73_RS09655	COG2190	(PTS) system
FORC73_RS09660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC73_RS09665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC73_RS09670	COG1702	phosphate starvation-inducible protein PhoH
FORC73_RS09675	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORC73_RS09680	COG4535	Mg2 and Co2 transporter CorC
FORC73_RS09685	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FORC73_RS09690	COG2888	peptidyl-tyrosine sulfation
FORC73_RS09695	COG0495	leucyl-tRNA aminoacylation
FORC73_RS09700	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FORC73_RS09705	COG1466	dna polymerase III delta subunit
FORC73_RS09710	COG0799	negative regulation of ribosome biogenesis
FORC73_RS09715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FORC73_RS09720	COG0768	penicillin binding
FORC73_RS09725	COG0772	Belongs to the SEDS family
FORC73_RS09730	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC73_RS09735	COG1686	Belongs to the peptidase S11 family
FORC73_RS09740	COG2921	Belongs to the UPF0250 family
FORC73_RS09745	COG0321	lipoyl(octanoyl) transferase activity
FORC73_RS09750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FORC73_RS09760	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC73_RS09785	COG1596	polysaccharide export
FORC73_RS09795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC73_RS09825	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FORC73_RS09835	COG0438	transferase activity, transferring glycosyl groups
FORC73_RS09845	COG1045	serine acetyltransferase
FORC73_RS09865	COG1045	serine acetyltransferase
FORC73_RS09870	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FORC73_RS09875	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC73_RS09880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC73_RS09885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC73_RS09915	COG0366	Alpha amylase catalytic
FORC73_RS09920	COG1263	PTS System
FORC73_RS09920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC73_RS09925	COG1609	Transcriptional regulator
FORC73_RS09930	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC73_RS09935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC73_RS09940	COG2011	ABC-type metal ion transport system permease component
FORC73_RS09945	COG1464	Belongs to the NlpA lipoprotein family
FORC73_RS09950	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FORC73_RS09960	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC73_RS09960	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC73_RS09975	COG1611	Belongs to the LOG family
FORC73_RS09980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC73_RS09985	COG2363	Small membrane protein
FORC73_RS09990	COG0583	DNA-binding transcription factor activity
FORC73_RS09995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC73_RS09995	COG0301	tRNA thio-modification
FORC73_RS10005	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC73_RS10010	COG1722	exodeoxyribonuclease VII activity
FORC73_RS10015	COG0142	geranyltranstransferase activity
FORC73_RS10020	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FORC73_RS10025	COG0564	pseudouridine synthase activity
FORC73_RS10030	COG3098	single-species biofilm formation
FORC73_RS10045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC73_RS10055	COG1671	Belongs to the UPF0178 family
FORC73_RS10060	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC73_RS10065	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC73_RS10070	COG0254	rRNA binding
FORC73_RS10075	COG1720	tRNA m6t6A37 methyltransferase activity
FORC73_RS10080	COG0442	prolyl-tRNA aminoacylation
FORC73_RS10100	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FORC73_RS10100	COG0047	phosphoribosylformylglycinamidine synthase activity
FORC73_RS10110	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FORC73_RS10120	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC73_RS10155	COG0484	heat shock protein binding
FORC73_RS10160	COG0443	Heat shock 70 kDa protein
FORC73_RS10165	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORC73_RS10170	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FORC73_RS10175	COG0497	DNA recombination
FORC73_RS10180	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC73_RS10185	COG2914	Belongs to the UPF0125 (RnfH) family
FORC73_RS10190	COG2867	negative regulation of translational initiation
FORC73_RS10195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FORC73_RS10205	COG0582	viral genome integration into host DNA
FORC73_RS10235	COG0210	DNA helicase
FORC73_RS10255	COG3501	Rhs element vgr protein
FORC73_RS10315	COG2003	Belongs to the UPF0758 family
FORC73_RS10370	COG1061	Type III restriction enzyme res subunit
FORC73_RS10385	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FORC73_RS10390	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FORC73_RS10395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC73_RS10415	COG3051	citrate lyase alpha subunit
FORC73_RS10420	COG2301	Belongs to the HpcH HpaI aldolase family
FORC73_RS10430	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FORC73_RS10440	COG3630	sodium ion export across plasma membrane
FORC73_RS10445	COG5016	pyruvate
FORC73_RS10445	COG0511	ligase activity, forming carbon-carbon bonds
FORC73_RS10450	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FORC73_RS10460	COG4565	transcriptional regulatory protein
FORC73_RS10475	COG0583	DNA-binding transcription factor activity
FORC73_RS10485	COG1115	amino acid carrier protein
FORC73_RS10490	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FORC73_RS10495	COG0583	DNA-binding transcription factor activity
FORC73_RS10505	COG1120	ATPase activity
FORC73_RS10510	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC73_RS10515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC73_RS10520	COG4592	Periplasmic binding protein
FORC73_RS10530	COG1028	Short-chain dehydrogenase reductase Sdr
FORC73_RS10535	COG1169	isochorismate synthase
FORC73_RS10540	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC73_RS10545	COG1535	isochorismatase
FORC73_RS10545	COG3433	isochorismatase activity
FORC73_RS10550	COG1584	GPR1 FUN34 yaaH family protein
FORC73_RS10685	COG0582	viral genome integration into host DNA
FORC73_RS10690	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORC73_RS10690	COG0519	Catalyzes the synthesis of GMP from XMP
FORC73_RS10695	COG0517	IMP dehydrogenase activity
FORC73_RS10695	COG0516	GMP reductase activity
FORC73_RS10700	COG1570	exodeoxyribonuclease VII activity
FORC73_RS10715	COG1160	GTP binding
FORC73_RS10720	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC73_RS10725	COG2976	Protein conserved in bacteria
FORC73_RS10730	COG0124	histidyl-tRNA synthetase
FORC73_RS10735	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FORC73_RS10750	COG0105	UTP biosynthetic process
FORC73_RS10755	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC73_RS10760	COG2975	iron-sulfur cluster assembly
FORC73_RS10765	COG0633	Ferredoxin
FORC73_RS10785	COG0822	iron-sulfur transferase activity
FORC73_RS10795	COG1959	2 iron, 2 sulfur cluster binding
FORC73_RS10805	COG0483	inositol monophosphate 1-phosphatase activity
FORC73_RS10810	COG3385	transposase activity
FORC73_RS10815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC73_RS10820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC73_RS10825	COG1862	Preprotein translocase
FORC73_RS10840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FORC73_RS10845	COG0517	IMP dehydrogenase activity
FORC73_RS10855	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC73_RS10860	COG0583	DNA-binding transcription factor activity
FORC73_RS10865	COG0450	alkyl hydroperoxide reductase
FORC73_RS10870	COG3142	Participates in the control of copper homeostasis
FORC73_RS10885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC73_RS10890	COG0581	inorganic phosphate transmembrane transporter activity
FORC73_RS10900	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FORC73_RS10905	COG0248	Ppx GppA phosphatase
FORC73_RS10920	COG0745	RESPONSE REGULATOR receiver
FORC73_RS10930	COG0826	peptidase U32
FORC73_RS10935	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC73_RS10975	COG0542	response to heat
FORC73_RS10980	COG1496	oxidoreductase activity
FORC73_RS10985	COG0564	pseudouridine synthase activity
FORC73_RS10990	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC73_RS10995	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC73_RS11000	COG1605	Chorismate mutase
FORC73_RS11000	COG0077	Prephenate dehydratase
FORC73_RS11005	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC73_RS11010	COG5001	Diguanylate cyclase
FORC73_RS11020	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FORC73_RS11030	COG0488	(ABC) transporter
FORC73_RS11040	COG0287	Prephenate dehydrogenase
FORC73_RS11040	COG1605	Chorismate mutase
FORC73_RS11045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC73_RS11050	COG3275	phosphorelay sensor kinase activity
FORC73_RS11055	COG3279	Response regulator of the LytR AlgR family
FORC73_RS11065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FORC73_RS11070	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC73_RS11080	COG1966	Carbon starvation protein
FORC73_RS11085	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FORC73_RS11090	COG1047	Peptidyl-prolyl cis-trans
FORC73_RS11095	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FORC73_RS11105	COG0196	riboflavin kinase activity
FORC73_RS11110	COG0728	peptidoglycan biosynthetic process
FORC73_RS11115	COG0268	Binds directly to 16S ribosomal RNA
FORC73_RS11120	COG0640	Transcriptional regulator
FORC73_RS11125	COG0583	DNA-binding transcription factor activity
FORC73_RS11130	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC73_RS11140	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FORC73_RS11145	COG0730	response to heat
FORC73_RS11150	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FORC73_RS11155	COG0494	nUDIX hydrolase
FORC73_RS11165	COG0667	Aldo Keto reductase
FORC73_RS11175	COG2204	response regulator
FORC73_RS11180	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FORC73_RS11200	COG0513	Belongs to the DEAD box helicase family
FORC73_RS11225	COG3153	acetyltransferase
FORC73_RS11230	COG3154	lipid carrier protein
FORC73_RS11240	COG0826	peptidase U32
FORC73_RS11245	COG0826	peptidase U32
FORC73_RS11265	COG1185	polyribonucleotide nucleotidyltransferase activity
FORC73_RS11270	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FORC73_RS11280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FORC73_RS11285	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FORC73_RS11290	COG0195	Participates in both transcription termination and antitermination
FORC73_RS11295	COG0779	Required for maturation of 30S ribosomal subunits
FORC73_RS11310	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC73_RS11325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC73_RS11330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC73_RS11335	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FORC73_RS11340	COG1534	Rna-binding protein
FORC73_RS11345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC73_RS11350	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC73_RS11360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC73_RS11365	COG0739	heme binding
FORC73_RS11380	COG0316	Belongs to the HesB IscA family
FORC73_RS11385	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FORC73_RS11390	COG0628	permease
FORC73_RS11395	COG2813	Specifically methylates the guanine in position
FORC73_RS11400	COG2205	protein histidine kinase activity
FORC73_RS11400	COG0784	Response regulator, receiver
FORC73_RS11410	COG0747	negative chemotaxis
FORC73_RS11415	COG0601	transmembrane transport
FORC73_RS11420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC73_RS11425	COG0444	Belongs to the ABC transporter superfamily
FORC73_RS11430	COG4608	Belongs to the ABC transporter superfamily
FORC73_RS11440	COG2971	BadF BadG BcrA BcrD
FORC73_RS11460	COG3842	ATPase activity
FORC73_RS11470	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC73_RS11475	COG0004	ammonium transporteR
FORC73_RS11480	COG0347	Belongs to the P(II) protein family
FORC73_RS11485	COG3112	Uncharacterised protein family (UPF0231)
FORC73_RS11490	COG1049	propionate catabolic process, 2-methylcitrate cycle
FORC73_RS11495	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC73_RS11500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC73_RS11505	COG1643	Atp-dependent helicase
FORC73_RS11515	COG1489	DNA binding
FORC73_RS11525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC73_RS11535	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC73_RS11540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FORC73_RS11545	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FORC73_RS11550	COG0842	Transport permease protein
FORC73_RS11555	COG1131	(ABC) transporter
FORC73_RS11560	COG0659	secondary active sulfate transmembrane transporter activity
FORC73_RS11565	COG0288	reversible hydration of carbon dioxide
FORC73_RS11585	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC73_RS11590	COG3107	peptidoglycan biosynthetic process
FORC73_RS11595	COG0792	nuclease activity
FORC73_RS11600	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC73_RS11605	COG2823	Periplasmic or secreted lipoprotein
FORC73_RS11610	COG2969	positive regulation of protein catabolic process
FORC73_RS11615	COG0625	glutathione transferase activity
FORC73_RS11620	COG2857	Cytochrome c1
FORC73_RS11630	COG0723	plastoquinol--plastocyanin reductase activity
FORC73_RS11635	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FORC73_RS11640	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FORC73_RS11645	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FORC73_RS11655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC73_RS11660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC73_RS11665	COG0335	large ribosomal subunit rRNA binding
FORC73_RS11670	COG0336	Belongs to the RNA methyltransferase TrmD family
FORC73_RS11675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FORC73_RS11680	COG0228	four-way junction DNA binding
FORC73_RS11685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC73_RS11690	COG4137	Cytochrome C assembly protein
FORC73_RS11695	COG4536	flavin adenine dinucleotide binding
FORC73_RS11700	COG1854	S-ribosylhomocysteine lyase activity
FORC73_RS11705	COG2918	glutathione biosynthetic process
FORC73_RS11710	COG0612	Peptidase, M16
FORC73_RS11715	COG1238	metal cluster binding
FORC73_RS11725	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FORC73_RS11730	COG5016	pyruvate
FORC73_RS11730	COG0511	ligase activity, forming carbon-carbon bonds
FORC73_RS11735	COG3630	sodium ion export across plasma membrane
FORC73_RS11780	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FORC73_RS11785	COG0527	aspartate kinase activity
FORC73_RS11790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC73_RS11795	COG2137	regulation of response to DNA damage stimulus
FORC73_RS11800	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FORC73_RS11810	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FORC73_RS11815	COG4208	sulfate ABC transporter
FORC73_RS11835	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FORC73_RS11840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC73_RS11850	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FORC73_RS11855	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FORC73_RS11860	COG0585	pseudouridine synthase activity
FORC73_RS11865	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FORC73_RS11870	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FORC73_RS11875	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FORC73_RS11880	COG1968	undecaprenyl-diphosphatase activity
FORC73_RS11885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC73_RS11890	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC73_RS11900	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FORC73_RS11910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FORC73_RS11915	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC73_RS11920	COG1610	YqeY-like protein
FORC73_RS11925	COG0358	DNA primase activity
FORC73_RS11945	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC73_RS11950	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FORC73_RS11955	COG1349	DNA-binding transcription factor activity
FORC73_RS11975	COG1279	arginine transmembrane transporter activity
FORC73_RS11980	COG0668	transmembrane transport
FORC73_RS11990	COG0191	fructose-bisphosphate aldolase activity
FORC73_RS11995	COG0126	phosphoglycerate kinase activity
FORC73_RS12000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC73_RS12005	COG4771	TonB-dependent receptor
FORC73_RS12010	COG0583	DNA-binding transcription factor activity
FORC73_RS12015	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC73_RS12025	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FORC73_RS12035	COG2356	endonuclease I
FORC73_RS12040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC73_RS12045	COG0189	ligase activity
FORC73_RS12050	COG1678	Uncharacterized ACR, COG1678
FORC73_RS12055	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FORC73_RS12060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC73_RS12080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC73_RS12085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC73_RS12090	COG0762	integral membrane protein
FORC73_RS12095	COG1872	DUF167
FORC73_RS12105	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FORC73_RS12110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC73_RS12115	COG2066	Belongs to the glutaminase family
FORC73_RS12120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FORC73_RS12125	COG1194	a g-specific adenine glycosylase
FORC73_RS12130	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FORC73_RS12135	COG0741	lytic transglycosylase activity
FORC73_RS12160	COG0840	transmembrane signaling receptor activity
FORC73_RS12190	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FORC73_RS12195	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FORC73_RS12200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC73_RS12205	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FORC73_RS12210	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FORC73_RS12215	COG2967	ApaG domain
FORC73_RS12220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC73_RS12230	COG3610	response to peptide
FORC73_RS12235	COG2966	Psort location CytoplasmicMembrane, score
FORC73_RS12240	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FORC73_RS12245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FORC73_RS12250	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FORC73_RS12255	COG0142	geranyltranstransferase activity
FORC73_RS12260	COG0531	amino acid
FORC73_RS12265	COG0039	L-malate dehydrogenase activity
FORC73_RS12270	COG1438	arginine binding
FORC73_RS12280	COG2358	TRAP transporter, solute receptor (TAXI family
FORC73_RS12290	COG0589	response to stress
FORC73_RS12315	COG2235	arginine
FORC73_RS12320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC73_RS12325	COG1151	hydroxylamine reductase activity
FORC73_RS12330	COG0312	modulator of DNA gyrase
FORC73_RS12335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC73_RS12340	COG3164	Protein of unknown function
FORC73_RS12350	COG0424	maF-like protein
FORC73_RS12355	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FORC73_RS12360	COG1792	Involved in formation and maintenance of cell shape
FORC73_RS12365	COG1077	Cell shape determining protein MreB Mrl
FORC73_RS12395	COG2165	general secretion pathway protein
FORC73_RS12400	COG2165	general secretion pathway protein
FORC73_RS12410	COG1459	type II secretion system
FORC73_RS12415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC73_RS12425	COG3267	Type II secretory pathway component ExeA
FORC73_RS12425	COG3409	Peptidoglycan-binding domain 1 protein
FORC73_RS12450	COG2199	diguanylate cyclase activity
FORC73_RS12450	COG2200	EAL domain
FORC73_RS12455	COG0629	single-stranded DNA binding
FORC73_RS12470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC73_RS12480	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC73_RS12485	COG0527	aspartate kinase activity
FORC73_RS12490	COG0646	methionine synthase
FORC73_RS12490	COG1410	methionine synthase
FORC73_RS12565	COG0175	sulfate reduction
FORC73_RS12570	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC73_RS12575	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC73_RS12600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC73_RS12605	COG0735	belongs to the Fur family
FORC73_RS12625	COG0432	Pfam Uncharacterised protein family UPF0047
FORC73_RS12630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC73_RS12645	COG0359	binds to the 23S rRNA
FORC73_RS12650	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FORC73_RS12655	COG2965	DNA replication, synthesis of RNA primer
FORC73_RS12660	COG0360	Binds together with S18 to 16S ribosomal RNA
FORC73_RS12670	COG2906	2 iron, 2 sulfur cluster binding
FORC73_RS12675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC73_RS12680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC73_RS12685	COG0049	tRNA binding
FORC73_RS12700	COG2923	Belongs to the DsrF TusC family
FORC73_RS12705	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FORC73_RS12710	COG2964	Protein conserved in bacteria
FORC73_RS12715	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC73_RS12725	COG2900	Belongs to the SlyX family
FORC73_RS12730	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FORC73_RS12735	COG0330	HflC and HflK could
FORC73_RS12740	COG0330	HflC and HflK could
FORC73_RS12745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC73_RS12750	COG1923	regulation of RNA biosynthetic process
FORC73_RS12755	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FORC73_RS12770	COG0802	atpase or kinase
FORC73_RS12775	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FORC73_RS12825	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FORC73_RS12830	COG1162	GTPase activity
FORC73_RS12835	COG0688	phosphatidylethanolamine metabolic process
FORC73_RS12840	COG0471	metal ion transport
FORC73_RS12850	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FORC73_RS12855	COG4942	peptidase
FORC73_RS12870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FORC73_RS12875	COG2816	NAD+ diphosphatase activity
FORC73_RS12880	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FORC73_RS12885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FORC73_RS12890	COG0085	RNA polymerase activity
FORC73_RS12895	COG0222	ribosome binding
FORC73_RS12900	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FORC73_RS12910	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FORC73_RS12915	COG0250	Participates in transcription elongation, termination and antitermination
FORC73_RS12920	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC73_RS12925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC73_RS12950	COG1072	(Pantothenic acid kinase))
FORC73_RS12960	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FORC73_RS12970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC73_RS13020	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FORC73_RS13035	COG3118	belongs to the thioredoxin family
FORC73_RS13040	COG0513	Belongs to the DEAD box helicase family
FORC73_RS13045	COG0248	Ppx GppA phosphatase
FORC73_RS13050	COG2205	protein histidine kinase activity
FORC73_RS13050	COG2202	Pas domain
FORC73_RS13055	COG2814	Major facilitator Superfamily
FORC73_RS13075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC73_RS13080	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FORC73_RS13085	COG0511	ligase activity, forming carbon-carbon bonds
FORC73_RS13090	COG0439	Biotin carboxylase
FORC73_RS13095	COG2264	protein methyltransferase activity
FORC73_RS13100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC73_RS13105	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FORC73_RS13110	COG1609	Transcriptional regulator
FORC73_RS13120	COG0387	Pfam Sodium calcium exchanger
FORC73_RS13125	COG0129	dihydroxy-acid dehydratase activity
FORC73_RS13130	COG3265	gluconokinase activity
FORC73_RS13140	COG0800	Aldolase
FORC73_RS13160	COG0840	transmembrane signaling receptor activity
FORC73_RS13165	COG1982	Orn Lys Arg decarboxylase major
FORC73_RS13170	COG0531	amino acid
FORC73_RS13175	COG3710	Transcriptional regulator
FORC73_RS13180	COG0789	Transcriptional regulator
FORC73_RS13195	COG0151	Belongs to the GarS family
FORC73_RS13205	COG0776	regulation of translation
FORC73_RS13210	COG1253	flavin adenine dinucleotide binding
FORC73_RS13220	COG3068	Protein conserved in bacteria
FORC73_RS13230	COG1573	uracil-dna glycosylase
FORC73_RS13235	COG0668	transmembrane transport
FORC73_RS13250	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FORC73_RS13260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC73_RS13265	COG0438	transferase activity, transferring glycosyl groups
FORC73_RS13285	COG1216	Glycosyl transferase, family 2
FORC73_RS13315	COG1596	polysaccharide export
FORC73_RS13335	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC73_RS13345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC73_RS13390	COG1213	nucleotidyl transferase
FORC73_RS13395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORC73_RS13395	COG0519	Catalyzes the synthesis of GMP from XMP
FORC73_RS13400	COG3848	Pyruvate phosphate dikinase
FORC73_RS13400	COG0574	Belongs to the PEP-utilizing enzyme family
FORC73_RS13410	COG1216	Glycosyl transferase, family 2
FORC73_RS13415	COG1132	(ABC) transporter
FORC73_RS13430	COG2030	dehydratase
FORC73_RS13435	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC73_RS13445	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FORC73_RS13455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC73_RS13480	COG0859	PFAM glycosyl transferase family 9
FORC73_RS13490	COG1519	Transferase
FORC73_RS13520	COG2755	lipolytic protein G-D-S-L family
FORC73_RS13520	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FORC73_RS13525	COG3642	lipopolysaccharide core region biosynthetic process
FORC73_RS13530	COG0859	PFAM glycosyl transferase family 9
FORC73_RS13535	COG0463	Glycosyl transferase, family 2
FORC73_RS13540	COG0859	PFAM glycosyl transferase family 9
FORC73_RS13545	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FORC73_RS13550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FORC73_RS13560	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FORC73_RS13565	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FORC73_RS13570	COG2003	Belongs to the UPF0758 family
FORC73_RS13580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC73_RS13590	COG1309	transcriptional regulator
FORC73_RS13595	COG1560	Kdo2-lipid A biosynthetic process
FORC73_RS13600	COG1560	Kdo2-lipid A biosynthetic process
FORC73_RS13605	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FORC73_RS13610	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FORC73_RS13615	COG1561	YicC-like family, N-terminal region
FORC73_RS13620	COG2862	Uncharacterized protein family, UPF0114
FORC73_RS13625	COG3385	transposase activity
FORC73_RS13630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC73_RS13630	COG1263	PTS System
FORC73_RS13635	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC73_RS13660	COG1120	ATPase activity
FORC73_RS13665	COG4774	siderophore transport
FORC73_RS13670	COG1132	(ABC) transporter
FORC73_RS13685	COG0514	ATP-dependent DNA helicase (RecQ)
FORC73_RS13690	COG2962	Rard protein
FORC73_RS13695	COG0405	Gamma-glutamyltransferase
FORC73_RS13705	COG1280	lysine exporter protein (LysE YggA)
FORC73_RS13720	COG0210	DNA helicase
FORC73_RS13730	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FORC73_RS13735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC73_RS13785	COG3621	Patatin-like phospholipase
FORC73_RS13830	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FORC73_RS13835	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FORC73_RS13865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC73_RS13870	COG0601	transmembrane transport
FORC73_RS13875	COG0747	negative chemotaxis
FORC73_RS13930	COG1309	transcriptional regulator
FORC73_RS13935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC73_RS13940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC73_RS13945	COG2960	long-chain fatty acid transporting porin activity
FORC73_RS13950	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FORC73_RS13955	COG0583	DNA-binding transcription factor activity
FORC73_RS14025	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FORC73_RS14030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC73_RS14035	COG1739	Uncharacterized protein family UPF0029
FORC73_RS14040	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC73_RS14040	COG1024	Enoyl-CoA hydratase
FORC73_RS14045	COG0183	Belongs to the thiolase family
FORC73_RS14050	COG0583	DNA-binding transcription factor activity
FORC73_RS14055	COG2814	Major facilitator Superfamily
FORC73_RS14065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FORC73_RS14070	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FORC73_RS14075	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FORC73_RS14080	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FORC73_RS14085	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FORC73_RS14090	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FORC73_RS14100	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC73_RS14105	COG3312	ion transport
FORC73_RS14110	COG1475	DNA binding
FORC73_RS14115	COG1192	Involved in chromosome partitioning
FORC73_RS14120	COG0357	Ribosomal RNA small subunit methyltransferase G
FORC73_RS14125	COG0445	tRNA wobble uridine modification
FORC73_RS14135	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC73_RS14165	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FORC73_RS14215	COG4974	Belongs to the 'phage' integrase family
FORC73_RS14220	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FORC73_RS14225	COG0706	membrane insertase activity
FORC73_RS14235	COG0594	ribonuclease P activity
FORC73_RS14240	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FORC73_RS14245	COG1126	abc transporter atp-binding protein
FORC73_RS14295	COG0217	transcriptional regulatory protein
FORC73_RS14300	COG2084	Dehydrogenase
FORC73_RS14320	COG2909	trisaccharide binding
FORC73_RS14325	COG0058	SHG alpha-glucan phosphorylase activity
FORC73_RS14330	COG1640	4-alpha-glucanotransferase
FORC73_RS14335	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FORC73_RS14355	COG3501	Rhs element vgr protein
FORC73_RS14390	COG0471	metal ion transport
FORC73_RS14395	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC73_RS14420	COG0840	transmembrane signaling receptor activity
FORC73_RS14440	COG0671	phosphoesterase, PA-phosphatase related
FORC73_RS14445	COG3385	transposase activity
FORC73_RS14450	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FORC73_RS14460	COG1999	signal sequence binding
FORC73_RS14475	COG0786	glutamate:sodium symporter activity
FORC73_RS14510	COG0813	purine-nucleoside phosphorylase activity
FORC73_RS14520	COG3272	Protein of unknown function (DUF1722)
FORC73_RS14530	COG0415	Belongs to the DNA photolyase family
FORC73_RS14535	COG1376	ErfK ybiS ycfS ynhG family protein
FORC73_RS14535	COG1388	LysM domain
FORC73_RS14545	COG0513	Belongs to the DEAD box helicase family
FORC73_RS14550	COG1770	oligopeptidase
FORC73_RS14575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC73_RS14580	COG0573	inorganic phosphate transmembrane transporter activity
FORC73_RS14585	COG0581	inorganic phosphate transmembrane transporter activity
FORC73_RS14590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC73_RS14610	COG3314	Sporulation integral membrane protein YlbJ
FORC73_RS14615	COG0659	secondary active sulfate transmembrane transporter activity
FORC73_RS14630	COG0739	heme binding
FORC73_RS14635	COG3300	MHYT domain
FORC73_RS14635	COG5001	Diguanylate cyclase
FORC73_RS14640	COG0583	DNA-binding transcription factor activity
FORC73_RS14645	COG2814	Major facilitator Superfamily
FORC73_RS14670	COG1301	dicarboxylic acid transport
FORC73_RS14680	COG1342	Belongs to the UPF0251 family
FORC73_RS14715	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC73_RS14730	COG2771	luxR family
FORC73_RS14730	COG2200	EAL domain
FORC73_RS14735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC73_RS14745	COG0564	pseudouridine synthase activity
FORC73_RS14815	COG3829	transcription factor binding
FORC73_RS14845	COG3409	Peptidoglycan-binding domain 1 protein
FORC73_RS14845	COG3501	Rhs element vgr protein
FORC73_RS14860	COG1869	D-ribose catabolic process
FORC73_RS14865	COG1129	ABC transporter
FORC73_RS14870	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC73_RS14875	COG1879	ABC-type sugar transport system periplasmic component
FORC73_RS14880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC73_RS14885	COG1609	Transcriptional regulator
FORC73_RS14895	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FORC73_RS14905	COG0584	glycerophosphoryl diester phosphodiesterase
FORC73_RS14910	COG2271	Major facilitator Superfamily
FORC73_RS14950	COG0579	oxidoreductase
FORC73_RS14960	COG0242	peptide deformylase activity
FORC73_RS14975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC73_RS14980	COG1609	Transcriptional regulator
FORC73_RS14985	COG1017	nitric oxide dioxygenase activity
FORC73_RS14985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC73_RS14990	COG1320	monovalent cation:proton antiporter activity
FORC73_RS14995	COG2212	antiporter activity
FORC73_RS15000	COG1863	multisubunit Na H antiporter MnhE subunit
FORC73_RS15005	COG0651	ATP synthesis coupled electron transport
FORC73_RS15010	COG1006	Multisubunit Na H antiporter MnhC subunit
FORC73_RS15025	COG0589	response to stress
FORC73_RS15030	COG0814	amino acid
FORC73_RS15050	COG3530	Putative quorum-sensing-regulated virulence factor
FORC73_RS15060	COG5001	Diguanylate cyclase
FORC73_RS15060	COG5002	protein histidine kinase activity
FORC73_RS15065	COG1278	Cold shock
FORC73_RS15080	COG2304	oxidoreductase activity
FORC73_RS15100	COG0714	Associated with various cellular activities
FORC73_RS15105	COG0840	transmembrane signaling receptor activity
FORC73_RS15120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC73_RS15125	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC73_RS15135	COG3604	Transcriptional regulator
FORC73_RS15140	COG1017	nitric oxide dioxygenase activity
FORC73_RS15140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC73_RS15145	COG1278	Cold shock
FORC73_RS15150	COG3036	rescue of stalled ribosome
FORC73_RS15175	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FORC73_RS15175	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FORC73_RS15180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC73_RS15190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC73_RS15205	COG0516	GMP reductase activity
FORC73_RS15220	COG0513	Belongs to the DEAD box helicase family
FORC73_RS15235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC73_RS15240	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FORC73_RS15245	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FORC73_RS15250	COG3437	response regulator, receiver
FORC73_RS15250	COG0784	Response regulator, receiver
FORC73_RS15255	COG4191	Histidine kinase
FORC73_RS15255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC73_RS15265	COG1757	Na H antiporter
FORC73_RS15270	COG2814	Major facilitator Superfamily
FORC73_RS15280	COG3706	GGDEF domain
FORC73_RS15285	COG3240	lipase activity
FORC73_RS15300	COG0840	transmembrane signaling receptor activity
FORC73_RS15305	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FORC73_RS15310	COG5380	lipid catabolic process
FORC73_RS15335	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC73_RS15340	COG4605	iron ion homeostasis
FORC73_RS15345	COG4604	ABC transporter, ATP-binding protein
FORC73_RS15350	COG2207	Transcriptional regulator
FORC73_RS15365	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC73_RS15395	COG3385	transposase activity
FORC73_RS15415	COG0745	RESPONSE REGULATOR receiver
FORC73_RS15425	COG3623	hexulose-6-phosphate isomerase
FORC73_RS15430	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FORC73_RS15435	COG0561	phosphatase activity
FORC73_RS15480	COG0745	RESPONSE REGULATOR receiver
FORC73_RS15485	COG5002	protein histidine kinase activity
FORC73_RS15535	COG1686	Belongs to the peptidase S11 family
FORC73_RS15555	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC73_RS15555	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC73_RS15560	COG0509	glycine decarboxylation via glycine cleavage system
FORC73_RS15565	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC73_RS15575	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FORC73_RS15590	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FORC73_RS15595	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FORC73_RS15655	COG0454	-acetyltransferase
FORC73_RS16055	COG0384	phenazine biosynthesis protein PhzF
FORC73_RS16100	COG3549	Plasmid maintenance system killer
FORC73_RS16105	COG3093	addiction module antidote protein HigA
FORC73_RS16140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC73_RS16160	COG2801	Transposase and inactivated derivatives
FORC73_RS16185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC73_RS16220	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
FORC73_RS16225	COG2944	sequence-specific DNA binding
FORC73_RS16245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC73_RS16305	COG2801	Transposase and inactivated derivatives
FORC73_RS16320	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC73_RS16370	COG1328	CTP reductase activity
FORC73_RS16375	COG0602	queuosine metabolic process
FORC73_RS16385	COG4067	protein conserved in archaea
FORC73_RS16385	COG0189	ligase activity
FORC73_RS16390	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FORC73_RS16390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC73_RS16390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC73_RS16395	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC73_RS16400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC73_RS16400	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC73_RS16405	COG1609	Transcriptional regulator
FORC73_RS16410	COG0420	3'-5' exonuclease activity
FORC73_RS16415	COG0419	ATPase involved in DNA repair
FORC73_RS16420	COG2205	protein histidine kinase activity
FORC73_RS16420	COG0784	Response regulator, receiver
FORC73_RS16425	COG0156	8-amino-7-oxononanoate synthase activity
FORC73_RS16435	COG0038	chloride channel
FORC73_RS16440	COG0523	cobalamin synthesis protein
FORC73_RS16455	COG2200	EAL domain
FORC73_RS16465	COG3038	cytochrome b561
FORC73_RS16475	COG2116	formate transmembrane transporter activity
FORC73_RS16480	COG0583	DNA-binding transcription factor activity
FORC73_RS16490	COG3593	DNA synthesis involved in DNA repair
FORC73_RS16495	COG0737	Belongs to the 5'-nucleotidase family
FORC73_RS16520	COG2824	Alkylphosphonate utilization operon protein PhnA
FORC73_RS16550	COG3385	transposase activity
FORC73_RS16560	COG2199	diguanylate cyclase activity
FORC73_RS16580	COG3706	GGDEF domain
FORC73_RS16595	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FORC73_RS16600	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FORC73_RS16610	COG0745	RESPONSE REGULATOR receiver
FORC73_RS16625	COG3140	Belongs to the UPF0181 family
FORC73_RS16765	COG0023	Translation Initiation Factor
FORC73_RS16785	COG1042	CoA-binding domain protein
FORC73_RS16785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC73_RS16785	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC73_RS16790	COG0583	DNA-binding transcription factor activity
FORC73_RS16795	COG4771	TonB-dependent receptor
FORC73_RS16810	COG2050	protein possibly involved in aromatic compounds catabolism
FORC73_RS16835	COG0625	glutathione transferase activity
FORC73_RS16850	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FORC73_RS16855	COG4172	Belongs to the ABC transporter superfamily
FORC73_RS16860	COG4239	(ABC) transporter, permease
FORC73_RS16865	COG4174	ABC transporter (Permease)
FORC73_RS16870	COG4166	transmembrane transport
FORC73_RS16905	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC73_RS16910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC73_RS16915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC73_RS16925	COG3842	ATPase activity
FORC73_RS16935	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC73_RS16950	COG1175	transmembrane transport
FORC73_RS16955	COG3833	ABC-type maltose transport systems, permease component
FORC73_RS16975	COG1011	Hydrolase
FORC73_RS16990	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FORC73_RS16995	COG1970	mechanosensitive ion channel activity
FORC73_RS17000	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FORC73_RS17005	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC73_RS17005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC73_RS17010	COG0302	gtp cyclohydrolase
FORC73_RS17020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC73_RS17030	COG2897	thiosulfate sulfurtransferase activity
FORC73_RS17040	COG2390	Transcriptional regulator
FORC73_RS17055	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC73_RS17085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC73_RS17110	COG0583	DNA-binding transcription factor activity
FORC73_RS17115	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FORC73_RS17155	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC73_RS17200	COG1263	PTS System
FORC73_RS17200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC73_RS17205	COG1609	Transcriptional regulator
FORC73_RS17210	COG1621	beta-fructofuranosidase activity
FORC73_RS17215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC73_RS17220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC73_RS17225	COG0840	transmembrane signaling receptor activity
FORC73_RS17235	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC73_RS17240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC73_RS17255	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC73_RS17260	COG1760	l-serine dehydratase
FORC73_RS17265	COG2197	response regulator
FORC73_RS17270	COG3850	Histidine kinase
FORC73_RS17275	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC73_RS17285	COG0243	molybdopterin cofactor binding
FORC73_RS17305	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC73_RS17310	COG2197	response regulator
FORC73_RS17315	COG3851	Histidine kinase
FORC73_RS17320	COG2271	Major facilitator Superfamily
FORC73_RS17325	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC73_RS17335	COG3842	ATPase activity
FORC73_RS17340	COG3243	poly(R)-hydroxyalkanoic acid synthase
FORC73_RS17350	COG0183	Belongs to the thiolase family
FORC73_RS17360	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC73_RS17365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC73_RS17390	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC73_RS17400	COG1979	alcohol dehydrogenase
FORC73_RS17415	COG4191	Histidine kinase
FORC73_RS17425	COG2271	Major facilitator Superfamily
FORC73_RS17430	COG0469	pyruvate kinase activity
FORC73_RS17435	COG2205	protein histidine kinase activity
FORC73_RS17435	COG2198	Histidine kinase
FORC73_RS17435	COG0784	Response regulator, receiver
FORC73_RS17440	COG1879	ABC-type sugar transport system periplasmic component
FORC73_RS17445	COG1803	Methylglyoxal synthase
FORC73_RS17450	COG1335	isochorismatase
FORC73_RS17455	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC73_RS17460	COG0210	DNA helicase
FORC73_RS17465	COG1289	transmembrane transporter activity
FORC73_RS17495	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FORC73_RS17500	COG4149	molybdate abc transporter
FORC73_RS17505	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC73_RS17510	COG1492	cobalamin metabolic process
FORC73_RS17545	COG5002	protein histidine kinase activity
FORC73_RS17545	COG0784	Response regulator, receiver
FORC73_RS17550	COG1879	ABC-type sugar transport system periplasmic component
FORC73_RS17560	COG2827	Endonuclease containing a URI domain
FORC73_RS17565	COG3132	Protein of unknown function, DUF480
FORC73_RS17575	COG2926	Belongs to the UPF0265 family
FORC73_RS17595	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC73_RS17605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC73_RS17615	COG0247	lactate metabolic process
FORC73_RS17620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC73_RS17625	COG3118	belongs to the thioredoxin family
FORC73_RS17650	COG4160	amino acid transport
FORC73_RS17655	COG4215	(ABC) transporter
FORC73_RS17660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC73_RS17665	COG1126	abc transporter atp-binding protein
FORC73_RS17675	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FORC73_RS17685	COG0494	nUDIX hydrolase
FORC73_RS17690	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC73_RS17700	COG1309	transcriptional regulator
FORC73_RS17705	COG0513	Belongs to the DEAD box helicase family
FORC73_RS17710	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FORC73_RS17720	COG0814	amino acid
FORC73_RS17725	COG0840	transmembrane signaling receptor activity
FORC73_RS17730	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC73_RS17740	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FORC73_RS17750	COG1984	allophanate hydrolase subunit 2
FORC73_RS17765	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FORC73_RS17770	COG4181	ATPase activity
FORC73_RS17780	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC73_RS17785	COG5001	Diguanylate cyclase
FORC73_RS17785	COG1716	ATPase activity
FORC73_RS17800	COG0484	heat shock protein binding
FORC73_RS17815	COG0546	phosphoglycolate phosphatase activity
FORC73_RS17830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC73_RS17840	COG0513	Belongs to the DEAD box helicase family
FORC73_RS17855	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC73_RS17865	COG3046	protein related to deoxyribodipyrimidine photolyase
FORC73_RS17870	COG3397	chitin binding
FORC73_RS17875	COG3227	Zinc metalloprotease (Elastase)
FORC73_RS17890	COG1166	arginine decarboxylase activity
FORC73_RS17900	COG2239	Acts as a magnesium transporter
FORC73_RS17905	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC73_RS17910	COG0459	protein refolding
FORC73_RS17920	COG0527	aspartate kinase activity
FORC73_RS17925	COG0662	Cupin 2, conserved barrel domain protein
FORC73_RS17930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC73_RS17935	COG0456	acetyltransferase
FORC73_RS17940	COG2154	pterin-4-alpha-carbinolamine dehydratase
FORC73_RS17945	COG3186	Phenylalanine-4-hydroxylase
FORC73_RS17950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC73_RS17970	COG2264	protein methyltransferase activity
FORC73_RS17995	COG1253	flavin adenine dinucleotide binding
FORC73_RS18000	COG1765	OsmC-like protein
FORC73_RS18030	COG0531	amino acid
FORC73_RS18050	COG4989	oxidoreductase activity
FORC73_RS18055	COG0366	Alpha amylase catalytic
FORC73_RS18065	COG2067	long-chain fatty acid transport protein
FORC73_RS18070	COG2267	carboxylic ester hydrolase activity
FORC73_RS18075	COG3227	Zinc metalloprotease (Elastase)
FORC73_RS18080	COG3047	cAMP biosynthetic process
FORC73_RS18090	COG1686	Belongs to the peptidase S11 family
FORC73_RS18100	COG1271	oxidase subunit
FORC73_RS18125	COG3048	D-serine ammonia-lyase activity
FORC73_RS18130	COG0583	DNA-binding transcription factor activity
FORC73_RS18145	COG0582	viral genome integration into host DNA
FORC73_RS18180	COG1063	alcohol dehydrogenase
FORC73_RS18185	COG0156	8-amino-7-oxononanoate synthase activity
FORC73_RS18190	COG2873	o-acetylhomoserine
FORC73_RS18200	COG0346	lactoylglutathione lyase activity
FORC73_RS18220	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC73_RS18225	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC73_RS18230	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC73_RS18235	COG0363	glucosamine-6-phosphate deaminase activity
FORC73_RS18240	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FORC73_RS18265	COG1929	Belongs to the glycerate kinase type-1 family
FORC73_RS18275	COG0748	coenzyme F420 binding
FORC73_RS18280	COG3721	Heme iron utilization protein
FORC73_RS18290	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC73_RS18295	COG0811	peptide transport
FORC73_RS18300	COG0848	biopolymer transport protein
FORC73_RS18305	COG4558	Periplasmic binding protein
FORC73_RS18310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC73_RS18315	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FORC73_RS18350	COG3217	Mosc domain protein beta barrel domain protein
FORC73_RS18350	COG0633	Ferredoxin
FORC73_RS18350	COG3217	Mosc domain protein beta barrel domain protein
FORC73_RS18350	COG0633	Ferredoxin
FORC73_RS18355	COG0418	dihydroorotase activity
FORC73_RS18365	COG3152	Membrane
FORC73_RS18375	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC73_RS18380	COG2354	Protein conserved in bacteria
FORC73_RS18385	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC73_RS18390	COG1278	Cold shock
FORC73_RS18420	COG2199	diguanylate cyclase activity
FORC73_RS18425	COG1349	DNA-binding transcription factor activity
FORC73_RS18440	COG3833	ABC-type maltose transport systems, permease component
FORC73_RS18445	COG1175	transmembrane transport
FORC73_RS18455	COG3842	ATPase activity
FORC73_RS18460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC73_RS18470	COG2801	Transposase and inactivated derivatives
FORC73_RS18480	COG0393	Putative heavy-metal-binding
FORC73_RS18490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC73_RS18495	COG0784	Response regulator, receiver
FORC73_RS18495	COG0835	chemotaxis
FORC73_RS18500	COG1846	Transcriptional regulator
FORC73_RS18505	COG3706	GGDEF domain
FORC73_RS18545	COG0583	DNA-binding transcription factor activity
FORC73_RS18550	COG5001	Diguanylate cyclase
FORC73_RS18560	COG1741	Belongs to the pirin family
FORC73_RS18565	COG3123	guanosine phosphorylase activity
FORC73_RS18575	COG2211	Major facilitator Superfamily
FORC73_RS18590	COG1067	ATP-dependent peptidase activity
FORC73_RS18600	COG4172	Belongs to the ABC transporter superfamily
FORC73_RS18625	COG0583	DNA-binding transcription factor activity
FORC73_RS18630	COG1620	l-lactate permease
FORC73_RS18645	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FORC73_RS18655	COG0840	transmembrane signaling receptor activity
FORC73_RS18665	COG0513	Belongs to the DEAD box helicase family
FORC73_RS18675	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC73_RS18695	COG1132	(ABC) transporter
FORC73_RS18705	COG1902	pentaerythritol trinitrate reductase activity
FORC73_RS18715	COG1280	lysine exporter protein (LysE YggA)
FORC73_RS18720	COG2207	Transcriptional regulator
FORC73_RS18740	COG1846	Transcriptional regulator
FORC73_RS18745	COG1764	response to oxidative stress
FORC73_RS18750	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC73_RS18755	COG0697	spore germination
FORC73_RS18765	COG0700	Nucleoside recognition
FORC73_RS18770	COG3366	ferrous iron transmembrane transporter activity
FORC73_RS18775	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC73_RS18785	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC73_RS18790	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC73_RS18795	COG2259	Doxx family
FORC73_RS18820	COG0363	glucosamine-6-phosphate deaminase activity
FORC73_RS18835	COG4580	involved in the transport of maltose and maltodextrins
FORC73_RS18850	COG0840	transmembrane signaling receptor activity
FORC73_RS18860	COG0840	transmembrane signaling receptor activity
FORC73_RS18870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC73_RS18875	COG1126	abc transporter atp-binding protein
FORC73_RS18885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC73_RS18890	COG4597	amino acid ABC transporter
FORC73_RS18895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC73_RS18900	COG2213	PTS system mannitol-specific
FORC73_RS18900	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC73_RS18905	COG0246	Mannitol dehydrogenase
FORC73_RS18910	COG3722	fumarate hydratase activity
FORC73_RS18940	COG0697	spore germination
FORC73_RS18955	COG1335	isochorismatase
FORC73_RS18965	COG2910	NAD(P)H-binding
FORC73_RS18975	COG0840	transmembrane signaling receptor activity
FORC73_RS18980	COG4221	oxidoreductase activity
FORC73_RS18990	COG1901	pseudouridine methyltransferase
FORC73_RS19005	COG0531	amino acid
FORC73_RS19010	COG1982	Orn Lys Arg decarboxylase major
FORC73_RS19045	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC73_RS19070	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FORC73_RS19105	COG3385	transposase activity
FORC73_RS19140	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC73_RS19145	COG0840	transmembrane signaling receptor activity
FORC73_RS19150	COG0835	chemotaxis
FORC73_RS19155	COG0835	chemotaxis
FORC73_RS19160	COG0643	Histidine kinase
FORC73_RS19160	COG2198	Histidine kinase
FORC73_RS19180	COG0601	transmembrane transport
FORC73_RS19185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC73_RS19195	COG2194	sulfuric ester hydrolase activity
FORC73_RS19200	COG0642	Histidine kinase
FORC73_RS19215	COG4221	oxidoreductase activity
FORC73_RS19235	COG1444	tRNA N-acetyltransferase activity
FORC73_RS19240	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine