locus-tag	class	description
FORC76_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FORC76_RS00010	COG0592	DNA-directed DNA polymerase activity
FORC76_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FORC76_RS00020	COG0187	DNA topoisomerase II activity
FORC76_RS00035	COG3385	transposase activity
FORC76_RS00040	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FORC76_RS00045	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC76_RS00055	COG0445	tRNA wobble uridine modification
FORC76_RS00060	COG0357	Ribosomal RNA small subunit methyltransferase G
FORC76_RS00065	COG1192	Involved in chromosome partitioning
FORC76_RS00070	COG1475	DNA binding
FORC76_RS00075	COG3312	ion transport
FORC76_RS00080	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC76_RS00090	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FORC76_RS00095	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FORC76_RS00100	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FORC76_RS00105	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FORC76_RS00110	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FORC76_RS00115	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FORC76_RS00125	COG2814	Major facilitator Superfamily
FORC76_RS00130	COG0583	DNA-binding transcription factor activity
FORC76_RS00135	COG0183	Belongs to the thiolase family
FORC76_RS00140	COG1024	Enoyl-CoA hydratase
FORC76_RS00140	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC76_RS00145	COG1739	Uncharacterized protein family UPF0029
FORC76_RS00150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC76_RS00155	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FORC76_RS00190	COG0583	DNA-binding transcription factor activity
FORC76_RS00195	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FORC76_RS00200	COG2960	long-chain fatty acid transporting porin activity
FORC76_RS00210	COG5433	transposase activity
FORC76_RS00220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC76_RS00225	COG1309	transcriptional regulator
FORC76_RS00270	COG0747	negative chemotaxis
FORC76_RS00275	COG0601	transmembrane transport
FORC76_RS00280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC76_RS00290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC76_RS00295	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FORC76_RS00305	COG0210	DNA helicase
FORC76_RS00310	COG1280	lysine exporter protein (LysE YggA)
FORC76_RS00320	COG2962	Rard protein
FORC76_RS00325	COG0514	ATP-dependent DNA helicase (RecQ)
FORC76_RS00340	COG1132	(ABC) transporter
FORC76_RS00345	COG4774	siderophore transport
FORC76_RS00350	COG1120	ATPase activity
FORC76_RS00375	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC76_RS00380	COG1263	PTS System
FORC76_RS00380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC76_RS00385	COG3385	transposase activity
FORC76_RS00390	COG2862	Uncharacterized protein family, UPF0114
FORC76_RS00405	COG1061	Type III restriction enzyme res subunit
FORC76_RS00435	COG0328	RNA-DNA hybrid ribonuclease activity
FORC76_RS00485	COG2003	Belongs to the UPF0758 family
FORC76_RS00490	COG2207	Transcriptional regulator
FORC76_RS00490	COG1917	Cupin 2, conserved barrel domain protein
FORC76_RS00495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC76_RS00510	COG1561	YicC-like family, N-terminal region
FORC76_RS00515	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FORC76_RS00520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FORC76_RS00525	COG1560	Kdo2-lipid A biosynthetic process
FORC76_RS00530	COG1560	Kdo2-lipid A biosynthetic process
FORC76_RS00535	COG1309	transcriptional regulator
FORC76_RS00545	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC76_RS00555	COG2003	Belongs to the UPF0758 family
FORC76_RS00560	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FORC76_RS00565	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FORC76_RS00575	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FORC76_RS00585	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FORC76_RS00590	COG0438	transferase activity, transferring glycosyl groups
FORC76_RS00595	COG0438	transferase activity, transferring glycosyl groups
FORC76_RS00600	COG0463	Glycosyl transferase, family 2
FORC76_RS00605	COG0859	PFAM glycosyl transferase family 9
FORC76_RS00610	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC76_RS00625	COG1519	Transferase
FORC76_RS00630	COG0859	PFAM glycosyl transferase family 9
FORC76_RS00635	COG3307	-O-antigen
FORC76_RS00640	COG1560	Kdo2-lipid A biosynthetic process
FORC76_RS00650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC76_RS00720	COG0438	transferase activity, transferring glycosyl groups
FORC76_RS00735	COG0438	transferase activity, transferring glycosyl groups
FORC76_RS00740	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FORC76_RS00745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC76_RS00750	COG1051	belongs to the nudix hydrolase family
FORC76_RS00780	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC76_RS00800	COG5433	transposase activity
FORC76_RS00805	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FORC76_RS00820	COG0668	transmembrane transport
FORC76_RS00830	COG3068	Protein conserved in bacteria
FORC76_RS00835	COG1253	flavin adenine dinucleotide binding
FORC76_RS00840	COG0776	regulation of translation
FORC76_RS00850	COG0151	Belongs to the GarS family
FORC76_RS00865	COG0789	Transcriptional regulator
FORC76_RS00870	COG3710	Transcriptional regulator
FORC76_RS00875	COG0531	amino acid
FORC76_RS00880	COG1982	Orn Lys Arg decarboxylase major
FORC76_RS00885	COG0840	transmembrane signaling receptor activity
FORC76_RS00895	COG0800	Aldolase
FORC76_RS00905	COG3265	gluconokinase activity
FORC76_RS00910	COG0129	dihydroxy-acid dehydratase activity
FORC76_RS00915	COG1609	Transcriptional regulator
FORC76_RS00920	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FORC76_RS00925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC76_RS00930	COG2264	protein methyltransferase activity
FORC76_RS00935	COG0439	Biotin carboxylase
FORC76_RS00940	COG0511	ligase activity, forming carbon-carbon bonds
FORC76_RS00945	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FORC76_RS00950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC76_RS00965	COG2814	Major facilitator Superfamily
FORC76_RS00970	COG2205	protein histidine kinase activity
FORC76_RS00970	COG0784	Response regulator, receiver
FORC76_RS00975	COG0248	Ppx GppA phosphatase
FORC76_RS00980	COG0513	Belongs to the DEAD box helicase family
FORC76_RS00985	COG3118	belongs to the thioredoxin family
FORC76_RS01000	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FORC76_RS01050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC76_RS01060	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FORC76_RS01070	COG1072	(Pantothenic acid kinase))
FORC76_RS01095	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC76_RS01100	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC76_RS01105	COG0250	Participates in transcription elongation, termination and antitermination
FORC76_RS01110	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FORC76_RS01120	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FORC76_RS01125	COG0222	ribosome binding
FORC76_RS01130	COG0085	RNA polymerase activity
FORC76_RS01135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FORC76_RS01140	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FORC76_RS01145	COG2816	NAD+ diphosphatase activity
FORC76_RS01150	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FORC76_RS01165	COG4942	peptidase
FORC76_RS01170	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FORC76_RS01180	COG0471	metal ion transport
FORC76_RS01185	COG0688	phosphatidylethanolamine metabolic process
FORC76_RS01190	COG1162	GTPase activity
FORC76_RS01195	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FORC76_RS01235	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FORC76_RS01240	COG0802	atpase or kinase
FORC76_RS01250	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FORC76_RS01255	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FORC76_RS01260	COG1923	regulation of RNA biosynthetic process
FORC76_RS01265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC76_RS01270	COG0330	HflC and HflK could
FORC76_RS01275	COG0330	HflC and HflK could
FORC76_RS01280	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FORC76_RS01285	COG2900	Belongs to the SlyX family
FORC76_RS01295	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC76_RS01300	COG2964	Protein conserved in bacteria
FORC76_RS01305	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FORC76_RS01310	COG2923	Belongs to the DsrF TusC family
FORC76_RS01325	COG0049	tRNA binding
FORC76_RS01330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC76_RS01335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC76_RS01340	COG2906	2 iron, 2 sulfur cluster binding
FORC76_RS01350	COG0360	Binds together with S18 to 16S ribosomal RNA
FORC76_RS01355	COG2965	DNA replication, synthesis of RNA primer
FORC76_RS01365	COG0359	binds to the 23S rRNA
FORC76_RS01380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC76_RS01385	COG0432	Pfam Uncharacterised protein family UPF0047
FORC76_RS01390	COG0166	Belongs to the GPI family
FORC76_RS01405	COG0735	belongs to the Fur family
FORC76_RS01410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC76_RS01430	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC76_RS01440	COG0175	sulfate reduction
FORC76_RS01520	COG0646	methionine synthase
FORC76_RS01520	COG1410	methionine synthase
FORC76_RS01525	COG0527	aspartate kinase activity
FORC76_RS01530	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC76_RS01540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC76_RS01555	COG0629	single-stranded DNA binding
FORC76_RS01560	COG2200	EAL domain
FORC76_RS01560	COG2199	diguanylate cyclase activity
FORC76_RS01585	COG3409	Peptidoglycan-binding domain 1 protein
FORC76_RS01585	COG3267	Type II secretory pathway component ExeA
FORC76_RS01595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC76_RS01600	COG1459	type II secretion system
FORC76_RS01645	COG1077	Cell shape determining protein MreB Mrl
FORC76_RS01650	COG1792	Involved in formation and maintenance of cell shape
FORC76_RS01655	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FORC76_RS01660	COG0424	maF-like protein
FORC76_RS01670	COG3164	Protein of unknown function
FORC76_RS01675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC76_RS01680	COG0312	modulator of DNA gyrase
FORC76_RS01685	COG1151	hydroxylamine reductase activity
FORC76_RS01690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC76_RS01695	COG2235	arginine
FORC76_RS01720	COG0589	response to stress
FORC76_RS01730	COG2358	TRAP transporter, solute receptor (TAXI family
FORC76_RS01740	COG1438	arginine binding
FORC76_RS01745	COG0039	L-malate dehydrogenase activity
FORC76_RS01750	COG0531	amino acid
FORC76_RS01755	COG0142	geranyltranstransferase activity
FORC76_RS01760	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FORC76_RS01765	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FORC76_RS01770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FORC76_RS01780	COG3610	response to peptide
FORC76_RS01795	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC76_RS01800	COG2967	ApaG domain
FORC76_RS01805	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FORC76_RS01810	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FORC76_RS01815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC76_RS01820	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FORC76_RS01825	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FORC76_RS01880	COG0741	lytic transglycosylase activity
FORC76_RS01885	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FORC76_RS01890	COG1194	a g-specific adenine glycosylase
FORC76_RS01895	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FORC76_RS01900	COG2066	Belongs to the glutaminase family
FORC76_RS01910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC76_RS01915	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FORC76_RS01930	COG0762	integral membrane protein
FORC76_RS01935	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC76_RS01940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC76_RS01965	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FORC76_RS01970	COG1678	Uncharacterized ACR, COG1678
FORC76_RS01975	COG0189	ligase activity
FORC76_RS01980	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC76_RS01985	COG2356	endonuclease I
FORC76_RS01990	COG3091	SprT-like family
FORC76_RS01995	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FORC76_RS02000	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC76_RS02005	COG0583	DNA-binding transcription factor activity
FORC76_RS02010	COG4771	TonB-dependent receptor
FORC76_RS02015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC76_RS02020	COG0126	phosphoglycerate kinase activity
FORC76_RS02025	COG0191	fructose-bisphosphate aldolase activity
FORC76_RS02030	COG0668	transmembrane transport
FORC76_RS02035	COG1279	arginine transmembrane transporter activity
FORC76_RS02055	COG1349	DNA-binding transcription factor activity
FORC76_RS02060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FORC76_RS02095	COG3645	SOS response
FORC76_RS02120	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FORC76_RS02145	COG2205	protein histidine kinase activity
FORC76_RS02145	COG0784	Response regulator, receiver
FORC76_RS02145	COG5002	protein histidine kinase activity
FORC76_RS02155	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC76_RS02205	COG0328	RNA-DNA hybrid ribonuclease activity
FORC76_RS02245	COG2003	Belongs to the UPF0758 family
FORC76_RS02275	COG0582	viral genome integration into host DNA
FORC76_RS02290	COG0358	DNA primase activity
FORC76_RS02295	COG1610	YqeY-like protein
FORC76_RS02300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC76_RS02305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FORC76_RS02315	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FORC76_RS02325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC76_RS02330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC76_RS02335	COG1968	undecaprenyl-diphosphatase activity
FORC76_RS02340	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FORC76_RS02345	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FORC76_RS02350	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FORC76_RS02355	COG0585	pseudouridine synthase activity
FORC76_RS02360	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FORC76_RS02365	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FORC76_RS02380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FORC76_RS02400	COG4208	sulfate ABC transporter
FORC76_RS02405	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FORC76_RS02415	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FORC76_RS02420	COG2137	regulation of response to DNA damage stimulus
FORC76_RS02425	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC76_RS02430	COG0527	aspartate kinase activity
FORC76_RS02435	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FORC76_RS02480	COG3630	sodium ion export across plasma membrane
FORC76_RS02485	COG0511	ligase activity, forming carbon-carbon bonds
FORC76_RS02485	COG5016	pyruvate
FORC76_RS02490	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FORC76_RS02500	COG1238	metal cluster binding
FORC76_RS02505	COG0612	Peptidase, M16
FORC76_RS02510	COG2918	glutathione biosynthetic process
FORC76_RS02515	COG1854	S-ribosylhomocysteine lyase activity
FORC76_RS02520	COG4536	flavin adenine dinucleotide binding
FORC76_RS02525	COG4137	Cytochrome C assembly protein
FORC76_RS02530	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC76_RS02535	COG0228	four-way junction DNA binding
FORC76_RS02540	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FORC76_RS02545	COG0336	Belongs to the RNA methyltransferase TrmD family
FORC76_RS02550	COG0335	large ribosomal subunit rRNA binding
FORC76_RS02555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC76_RS02560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC76_RS02570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FORC76_RS02575	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FORC76_RS02580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FORC76_RS02585	COG0723	plastoquinol--plastocyanin reductase activity
FORC76_RS02590	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC76_RS02595	COG2857	Cytochrome c1
FORC76_RS02600	COG0625	glutathione transferase activity
FORC76_RS02605	COG2969	positive regulation of protein catabolic process
FORC76_RS02610	COG2823	Periplasmic or secreted lipoprotein
FORC76_RS02615	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC76_RS02620	COG0792	nuclease activity
FORC76_RS02625	COG3107	peptidoglycan biosynthetic process
FORC76_RS02630	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC76_RS02645	COG0288	reversible hydration of carbon dioxide
FORC76_RS02650	COG0659	secondary active sulfate transmembrane transporter activity
FORC76_RS02655	COG1131	(ABC) transporter
FORC76_RS02660	COG0842	Transport permease protein
FORC76_RS02665	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FORC76_RS02670	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FORC76_RS02675	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC76_RS02685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC76_RS02695	COG1489	DNA binding
FORC76_RS02705	COG1643	Atp-dependent helicase
FORC76_RS02710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC76_RS02715	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC76_RS02720	COG1049	propionate catabolic process, 2-methylcitrate cycle
FORC76_RS02725	COG3112	Uncharacterised protein family (UPF0231)
FORC76_RS02730	COG0347	Belongs to the P(II) protein family
FORC76_RS02735	COG0004	ammonium transporteR
FORC76_RS02740	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC76_RS02750	COG3842	ATPase activity
FORC76_RS02755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC76_RS02770	COG2971	BadF BadG BcrA BcrD
FORC76_RS02780	COG4608	Belongs to the ABC transporter superfamily
FORC76_RS02785	COG0444	Belongs to the ABC transporter superfamily
FORC76_RS02790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC76_RS02800	COG0747	negative chemotaxis
FORC76_RS02805	COG0784	Response regulator, receiver
FORC76_RS02805	COG2205	protein histidine kinase activity
FORC76_RS02810	COG2813	Specifically methylates the guanine in position
FORC76_RS02815	COG0628	permease
FORC76_RS02820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FORC76_RS02825	COG0316	Belongs to the HesB IscA family
FORC76_RS02840	COG0739	heme binding
FORC76_RS02845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC76_RS02850	COG2027	D-alanyl-D-alanine carboxypeptidase
FORC76_RS02855	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC76_RS02860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC76_RS02865	COG1534	Rna-binding protein
FORC76_RS02870	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FORC76_RS02875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC76_RS02880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC76_RS02895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC76_RS02910	COG0779	Required for maturation of 30S ribosomal subunits
FORC76_RS02915	COG0195	Participates in both transcription termination and antitermination
FORC76_RS02920	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FORC76_RS02925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FORC76_RS02935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FORC76_RS02960	COG0826	peptidase U32
FORC76_RS02965	COG0826	peptidase U32
FORC76_RS02975	COG3154	lipid carrier protein
FORC76_RS02980	COG3153	acetyltransferase
FORC76_RS03005	COG0513	Belongs to the DEAD box helicase family
FORC76_RS03025	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FORC76_RS03030	COG2204	response regulator
FORC76_RS03040	COG0667	Aldo Keto reductase
FORC76_RS03045	COG3066	DNA modification
FORC76_RS03080	COG0583	DNA-binding transcription factor activity
FORC76_RS03085	COG0640	Transcriptional regulator
FORC76_RS03090	COG0268	Binds directly to 16S ribosomal RNA
FORC76_RS03095	COG0728	peptidoglycan biosynthetic process
FORC76_RS03100	COG0196	riboflavin kinase activity
FORC76_RS03110	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FORC76_RS03115	COG1047	Peptidyl-prolyl cis-trans
FORC76_RS03120	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FORC76_RS03125	COG1966	Carbon starvation protein
FORC76_RS03135	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC76_RS03150	COG3279	Response regulator of the LytR AlgR family
FORC76_RS03155	COG3275	phosphorelay sensor kinase activity
FORC76_RS03160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC76_RS03165	COG1605	Chorismate mutase
FORC76_RS03165	COG0287	Prephenate dehydrogenase
FORC76_RS03175	COG0488	(ABC) transporter
FORC76_RS03185	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FORC76_RS03195	COG5001	Diguanylate cyclase
FORC76_RS03200	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC76_RS03205	COG0077	Prephenate dehydratase
FORC76_RS03205	COG1605	Chorismate mutase
FORC76_RS03210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC76_RS03215	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC76_RS03220	COG0564	pseudouridine synthase activity
FORC76_RS03225	COG1496	oxidoreductase activity
FORC76_RS03230	COG0542	response to heat
FORC76_RS03280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC76_RS03285	COG0826	peptidase U32
FORC76_RS03295	COG0745	RESPONSE REGULATOR receiver
FORC76_RS03300	COG5002	protein histidine kinase activity
FORC76_RS03310	COG0248	Ppx GppA phosphatase
FORC76_RS03315	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FORC76_RS03325	COG0581	inorganic phosphate transmembrane transporter activity
FORC76_RS03330	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC76_RS03350	COG3142	Participates in the control of copper homeostasis
FORC76_RS03355	COG0450	alkyl hydroperoxide reductase
FORC76_RS03360	COG0583	DNA-binding transcription factor activity
FORC76_RS03365	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC76_RS03375	COG0517	IMP dehydrogenase activity
FORC76_RS03380	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FORC76_RS03395	COG1862	Preprotein translocase
FORC76_RS03400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC76_RS03405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC76_RS03410	COG0483	inositol monophosphate 1-phosphatase activity
FORC76_RS03420	COG1959	2 iron, 2 sulfur cluster binding
FORC76_RS03430	COG0822	iron-sulfur transferase activity
FORC76_RS03440	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FORC76_RS03450	COG0633	Ferredoxin
FORC76_RS03455	COG2975	iron-sulfur cluster assembly
FORC76_RS03460	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC76_RS03465	COG0105	UTP biosynthetic process
FORC76_RS03470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FORC76_RS03475	COG1426	Protein conserved in bacteria
FORC76_RS03480	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FORC76_RS03485	COG0124	histidyl-tRNA synthetase
FORC76_RS03490	COG2976	Protein conserved in bacteria
FORC76_RS03495	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC76_RS03500	COG1160	GTP binding
FORC76_RS03515	COG1570	exodeoxyribonuclease VII activity
FORC76_RS03520	COG0516	GMP reductase activity
FORC76_RS03520	COG0517	IMP dehydrogenase activity
FORC76_RS03525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORC76_RS03525	COG0519	Catalyzes the synthesis of GMP from XMP
FORC76_RS03535	COG1584	GPR1 FUN34 yaaH family protein
FORC76_RS03540	COG3433	isochorismatase activity
FORC76_RS03540	COG1535	isochorismatase
FORC76_RS03545	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC76_RS03550	COG1169	isochorismate synthase
FORC76_RS03555	COG1028	Short-chain dehydrogenase reductase Sdr
FORC76_RS03565	COG4592	Periplasmic binding protein
FORC76_RS03570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC76_RS03575	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC76_RS03580	COG1120	ATPase activity
FORC76_RS03585	COG2977	Belongs to the P-Pant transferase superfamily
FORC76_RS03590	COG1115	amino acid carrier protein
FORC76_RS03600	COG0583	DNA-binding transcription factor activity
FORC76_RS03615	COG4565	transcriptional regulatory protein
FORC76_RS03625	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FORC76_RS03630	COG5016	pyruvate
FORC76_RS03630	COG0511	ligase activity, forming carbon-carbon bonds
FORC76_RS03645	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FORC76_RS03650	COG3052	prosthetic group binding
FORC76_RS03655	COG2301	Belongs to the HpcH HpaI aldolase family
FORC76_RS03660	COG3051	citrate lyase alpha subunit
FORC76_RS03675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC76_RS03680	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FORC76_RS03685	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FORC76_RS03695	COG3842	ATPase activity
FORC76_RS03700	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC76_RS03705	COG0583	DNA-binding transcription factor activity
FORC76_RS03780	COG2003	Belongs to the UPF0758 family
FORC76_RS03800	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FORC76_RS03800	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FORC76_RS03835	COG3501	Rhs element vgr protein
FORC76_RS03850	COG1518	maintenance of DNA repeat elements
FORC76_RS03880	COG0582	viral genome integration into host DNA
FORC76_RS03890	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FORC76_RS03895	COG2867	negative regulation of translational initiation
FORC76_RS03900	COG2914	Belongs to the UPF0125 (RnfH) family
FORC76_RS03905	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC76_RS03915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FORC76_RS03920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORC76_RS03925	COG0443	Heat shock 70 kDa protein
FORC76_RS03930	COG0484	heat shock protein binding
FORC76_RS03965	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC76_RS03975	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FORC76_RS03985	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FORC76_RS03985	COG0047	phosphoribosylformylglycinamidine synthase activity
FORC76_RS04000	COG0442	prolyl-tRNA aminoacylation
FORC76_RS04005	COG1720	tRNA m6t6A37 methyltransferase activity
FORC76_RS04010	COG0254	rRNA binding
FORC76_RS04015	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC76_RS04020	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC76_RS04025	COG1671	Belongs to the UPF0178 family
FORC76_RS04035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC76_RS04050	COG3098	single-species biofilm formation
FORC76_RS04055	COG0564	pseudouridine synthase activity
FORC76_RS04070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FORC76_RS04075	COG0142	geranyltranstransferase activity
FORC76_RS04080	COG1722	exodeoxyribonuclease VII activity
FORC76_RS04085	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC76_RS04095	COG0301	tRNA thio-modification
FORC76_RS04095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC76_RS04100	COG0583	DNA-binding transcription factor activity
FORC76_RS04105	COG2363	Small membrane protein
FORC76_RS04110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC76_RS04115	COG1611	Belongs to the LOG family
FORC76_RS04130	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC76_RS04130	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC76_RS04140	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FORC76_RS04145	COG1464	Belongs to the NlpA lipoprotein family
FORC76_RS04150	COG2011	ABC-type metal ion transport system permease component
FORC76_RS04155	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC76_RS04160	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC76_RS04165	COG1609	Transcriptional regulator
FORC76_RS04170	COG1263	PTS System
FORC76_RS04170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC76_RS04175	COG0366	Alpha amylase catalytic
FORC76_RS04200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC76_RS04205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC76_RS04210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC76_RS04215	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FORC76_RS04220	COG1045	serine acetyltransferase
FORC76_RS04240	COG1045	serine acetyltransferase
FORC76_RS04250	COG0438	transferase activity, transferring glycosyl groups
FORC76_RS04260	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FORC76_RS04290	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC76_RS04300	COG1596	polysaccharide export
FORC76_RS04325	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC76_RS04335	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FORC76_RS04340	COG0321	lipoyl(octanoyl) transferase activity
FORC76_RS04345	COG2921	Belongs to the UPF0250 family
FORC76_RS04350	COG1686	Belongs to the peptidase S11 family
FORC76_RS04355	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC76_RS04360	COG0772	Belongs to the SEDS family
FORC76_RS04365	COG0768	penicillin binding
FORC76_RS04370	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FORC76_RS04375	COG0799	negative regulation of ribosome biogenesis
FORC76_RS04380	COG1466	dna polymerase III delta subunit
FORC76_RS04385	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FORC76_RS04390	COG0495	leucyl-tRNA aminoacylation
FORC76_RS04395	COG2888	peptidyl-tyrosine sulfation
FORC76_RS04400	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FORC76_RS04405	COG4535	Mg2 and Co2 transporter CorC
FORC76_RS04410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORC76_RS04415	COG1702	phosphate starvation-inducible protein PhoH
FORC76_RS04420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC76_RS04425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC76_RS04460	COG2190	(PTS) system
FORC76_RS04470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC76_RS04480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC76_RS04485	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FORC76_RS04490	COG3115	cell septum assembly
FORC76_RS04495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FORC76_RS04515	COG0789	Transcriptional regulator
FORC76_RS04520	COG1585	Membrane protein implicated in regulation of membrane protease activity
FORC76_RS04525	COG0330	HflC and HflK could
FORC76_RS04530	COG3118	belongs to the thioredoxin family
FORC76_RS04540	COG0300	oxidoreductase activity
FORC76_RS04545	COG1090	epimerase
FORC76_RS04550	COG0622	Phosphoesterase
FORC76_RS04565	COG3710	Transcriptional regulator
FORC76_RS04570	COG0326	Molecular chaperone. Has ATPase activity
FORC76_RS04575	COG0563	adenylate kinase activity
FORC76_RS04580	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FORC76_RS04585	COG3104	oligopeptide transport
FORC76_RS04595	COG0367	asparagine synthase
FORC76_RS04600	COG4651	solute:proton antiporter activity
FORC76_RS04600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC76_RS04610	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC76_RS04615	COG2190	(PTS) system
FORC76_RS04615	COG1263	PTS System
FORC76_RS04615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC76_RS04630	COG0101	tRNA pseudouridine synthase activity
FORC76_RS04635	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC76_RS04640	COG0285	dihydrofolate synthase activity
FORC76_RS04645	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FORC76_RS04650	COG1286	toxin biosynthetic process
FORC76_RS04655	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC76_RS04660	COG2056	Na+-H+ antiporter family
FORC76_RS04665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC76_RS04680	COG0346	lactoylglutathione lyase activity
FORC76_RS04685	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC76_RS04690	COG4660	Part of a membrane complex involved in electron transport
FORC76_RS04705	COG4656	Part of a membrane complex involved in electron transport
FORC76_RS04710	COG2878	Part of a membrane complex involved in electron transport
FORC76_RS04715	COG4657	Part of a membrane complex involved in electron transport
FORC76_RS04725	COG0556	nucleotide-excision repair
FORC76_RS04735	COG2204	response regulator
FORC76_RS04740	COG2198	Histidine kinase
FORC76_RS04745	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC76_RS04750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC76_RS04755	COG0521	Mo-molybdopterin cofactor biosynthetic process
FORC76_RS04760	COG0315	cyclic pyranopterin monophosphate synthase activity
FORC76_RS04765	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FORC76_RS04770	COG0314	molybdopterin synthase activity
FORC76_RS04775	COG2199	diguanylate cyclase activity
FORC76_RS04780	COG0517	IMP dehydrogenase activity
FORC76_RS04780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FORC76_RS04780	COG0617	tRNA 3'-terminal CCA addition
FORC76_RS04795	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FORC76_RS04805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC76_RS04805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC76_RS04810	COG0489	protein tyrosine kinase activity
FORC76_RS04820	COG0572	uridine kinase
FORC76_RS04825	COG2982	Protein involved in outer membrane biogenesis
FORC76_RS04830	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FORC76_RS04835	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC76_RS04845	COG2067	long-chain fatty acid transport protein
FORC76_RS04865	COG0183	Belongs to the thiolase family
FORC76_RS04870	COG1024	Enoyl-CoA hydratase
FORC76_RS04870	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC76_RS04875	COG0778	Nitroreductase
FORC76_RS04880	COG0583	DNA-binding transcription factor activity
FORC76_RS04885	COG0745	RESPONSE REGULATOR receiver
FORC76_RS04895	COG2832	Protein of unknown function (DUF454)
FORC76_RS04900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC76_RS04910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FORC76_RS04915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FORC76_RS04925	COG0733	neurotransmitter:sodium symporter activity
FORC76_RS04940	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC76_RS04950	COG1940	carbohydrate kinase activity
FORC76_RS04955	COG0784	Response regulator, receiver
FORC76_RS04955	COG0835	chemotaxis
FORC76_RS04970	COG2226	methyltransferase
FORC76_RS04980	COG0676	glucose-6-phosphate 1-epimerase activity
FORC76_RS04985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC76_RS04990	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC76_RS05000	COG3139	Protein of unknown function (DUF1315)
FORC76_RS05005	COG0252	asparaginase activity
FORC76_RS05010	COG0616	signal peptide processing
FORC76_RS05015	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC76_RS05015	COG1902	pentaerythritol trinitrate reductase activity
FORC76_RS05020	COG0788	formyltetrahydrofolate deformylase activity
FORC76_RS05035	COG1199	ATP-dependent helicase activity
FORC76_RS05040	COG1214	PFAM Peptidase M22, glycoprotease
FORC76_RS05055	COG2267	carboxylic ester hydrolase activity
FORC76_RS05060	COG0318	PFAM AMP-dependent synthetase and ligase
FORC76_RS05065	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FORC76_RS05070	COG0705	Rhomboid family
FORC76_RS05080	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FORC76_RS05085	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FORC76_RS05090	COG0436	Aminotransferase
FORC76_RS05095	COG1169	isochorismate synthase
FORC76_RS05100	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FORC76_RS05105	COG0596	Alpha beta hydrolase
FORC76_RS05125	COG3135	benzoate transporter
FORC76_RS05130	COG1396	sequence-specific DNA binding
FORC76_RS05135	COG0840	transmembrane signaling receptor activity
FORC76_RS05160	COG3015	lipoprotein NlpE involved in copper resistance
FORC76_RS05165	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FORC76_RS05170	COG2894	cell division
FORC76_RS05175	COG0850	regulation of cytokinetic process
FORC76_RS05180	COG3100	YcgL domain-containing protein
FORC76_RS05195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC76_RS05200	COG3005	denitrification pathway
FORC76_RS05205	COG0243	molybdopterin cofactor binding
FORC76_RS05225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC76_RS05240	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FORC76_RS05270	COG5001	Diguanylate cyclase
FORC76_RS05270	COG3300	MHYT domain
FORC76_RS05290	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC76_RS05295	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC76_RS05300	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC76_RS05310	COG4191	Histidine kinase
FORC76_RS05320	COG0544	peptidyl-prolyl cis-trans isomerase activity
FORC76_RS05330	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FORC76_RS05335	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FORC76_RS05340	COG0776	regulation of translation
FORC76_RS05345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC76_RS05350	COG1555	photosystem II stabilization
FORC76_RS05355	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FORC76_RS05360	COG0539	negative regulation of cytoplasmic translation
FORC76_RS05365	COG0776	regulation of translation
FORC76_RS05370	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FORC76_RS05375	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FORC76_RS05395	COG0583	DNA-binding transcription factor activity
FORC76_RS05405	COG0686	Belongs to the AlaDH PNT family
FORC76_RS05415	COG1674	ftsk spoiiie
FORC76_RS05420	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FORC76_RS05425	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC76_RS05430	COG2186	Transcriptional regulator
FORC76_RS05445	COG0537	adenosine 5'-monophosphoramidase activity
FORC76_RS05470	COG3150	esterase
FORC76_RS05475	COG1252	NADH dehydrogenase
FORC76_RS05500	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC76_RS05510	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC76_RS05515	COG1136	(ABC) transporter
FORC76_RS05520	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC76_RS05530	COG2333	competence protein COMEC
FORC76_RS05530	COG0658	competence protein
FORC76_RS05535	COG1132	(ABC) transporter
FORC76_RS05540	COG1663	tetraacyldisaccharide 4'-kinase activity
FORC76_RS05545	COG2835	tetraacyldisaccharide 4'-kinase activity
FORC76_RS05550	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORC76_RS05555	COG2719	SpoVR family
FORC76_RS05560	COG2718	Belongs to the UPF0229 family
FORC76_RS05565	COG2766	serine protein kinase
FORC76_RS05575	COG3013	Belongs to the UPF0304 family
FORC76_RS05580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC76_RS05595	COG1882	Formate acetyltransferase
FORC76_RS05620	COG4160	amino acid transport
FORC76_RS05625	COG0708	Exodeoxyribonuclease III
FORC76_RS05630	COG0840	transmembrane signaling receptor activity
FORC76_RS05640	COG3923	Primosomal replication protein n
FORC76_RS05645	COG0730	response to heat
FORC76_RS05650	COG1199	ATP-dependent helicase activity
FORC76_RS05655	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC76_RS05665	COG3012	SEC-C Motif Domain Protein
FORC76_RS05670	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC76_RS05675	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC76_RS05680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC76_RS05685	COG0215	cysteine-tRNA ligase activity
FORC76_RS05690	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FORC76_RS05695	COG0632	four-way junction helicase activity
FORC76_RS05705	COG1271	oxidase subunit
FORC76_RS05710	COG1294	oxidase, subunit
FORC76_RS05715	COG4890	Cyd operon protein YbgT
FORC76_RS05720	COG3790	cyd operon protein YbgE
FORC76_RS05725	COG0824	Thioesterase
FORC76_RS05730	COG0811	peptide transport
FORC76_RS05745	COG0823	Involved in the tonB-independent uptake of proteins
FORC76_RS05750	COG2885	chlorophyll binding
FORC76_RS05760	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FORC76_RS05770	COG5002	protein histidine kinase activity
FORC76_RS05770	COG0784	Response regulator, receiver
FORC76_RS05780	COG1012	belongs to the aldehyde dehydrogenase family
FORC76_RS05785	COG3284	Transcriptional regulator
FORC76_RS05790	COG4628	conserved protein (DUF2132)
FORC76_RS05800	COG0415	Belongs to the DNA photolyase family
FORC76_RS05810	COG5001	Diguanylate cyclase
FORC76_RS05835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC76_RS05845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC76_RS05845	COG3008	intermembrane lipid transfer
FORC76_RS05850	COG2995	paraquat-inducible protein a
FORC76_RS05855	COG1309	transcriptional regulator
FORC76_RS05860	COG1012	belongs to the aldehyde dehydrogenase family
FORC76_RS05885	COG1960	acyl-CoA dehydrogenase activity
FORC76_RS05890	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC76_RS05895	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FORC76_RS05905	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FORC76_RS05925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC76_RS05930	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC76_RS05935	COG0297	glycogen (starch) synthase activity
FORC76_RS05955	COG3070	regulator of competence-specific genes
FORC76_RS05960	COG1609	Transcriptional regulator
FORC76_RS05975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC76_RS05980	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FORC76_RS05985	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FORC76_RS06005	COG1032	radical SAM domain protein
FORC76_RS06010	COG5001	Diguanylate cyclase
FORC76_RS06015	COG0612	Peptidase, M16
FORC76_RS06030	COG0583	DNA-binding transcription factor activity
FORC76_RS06035	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FORC76_RS06045	COG2350	Protein conserved in bacteria
FORC76_RS06050	COG1607	acyl-coa hydrolase
FORC76_RS06065	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC76_RS06070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC76_RS06085	COG2116	formate transmembrane transporter activity
FORC76_RS06105	COG1227	inorganic diphosphatase activity
FORC76_RS06120	COG4172	Belongs to the ABC transporter superfamily
FORC76_RS06135	COG4168	peptide transport system, permease
FORC76_RS06145	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC76_RS06150	COG1842	Phage shock protein A
FORC76_RS06165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC76_RS06180	COG2818	Glycosylase
FORC76_RS06185	COG0589	response to stress
FORC76_RS06195	COG0626	cystathionine gamma-synthase activity
FORC76_RS06205	COG0733	neurotransmitter:sodium symporter activity
FORC76_RS06210	COG0564	pseudouridine synthase activity
FORC76_RS06215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC76_RS06220	COG4136	ATPase activity
FORC76_RS06225	COG4135	transport system, permease component
FORC76_RS06230	COG4134	Bacterial extracellular solute-binding protein
FORC76_RS06240	COG3313	Fe-S protein
FORC76_RS06250	COG0814	amino acid
FORC76_RS06260	COG2239	Acts as a magnesium transporter
FORC76_RS06275	COG4934	collagen metabolic process
FORC76_RS06305	COG0840	transmembrane signaling receptor activity
FORC76_RS06320	COG4251	negative regulation of phosphorylation
FORC76_RS06320	COG3706	GGDEF domain
FORC76_RS06320	COG2203	Gaf domain
FORC76_RS06320	COG5001	Diguanylate cyclase
FORC76_RS06325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FORC76_RS06345	COG1061	Type III restriction enzyme res subunit
FORC76_RS06350	COG1187	pseudouridine synthase activity
FORC76_RS06355	COG2814	Major facilitator Superfamily
FORC76_RS06370	COG0534	Mate efflux family protein
FORC76_RS06375	COG4181	ATPase activity
FORC76_RS06380	COG0577	efflux transmembrane transporter activity
FORC76_RS06390	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC76_RS06405	COG1748	Saccharopine dehydrogenase
FORC76_RS06435	COG0583	DNA-binding transcription factor activity
FORC76_RS06445	COG1451	nucleotide metabolic process
FORC76_RS06460	COG3063	Type IV pilus biogenesis stability protein PilW
FORC76_RS06465	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FORC76_RS06485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC76_RS06500	COG3290	protein histidine kinase activity
FORC76_RS06505	COG4565	transcriptional regulatory protein
FORC76_RS06515	COG0784	Response regulator, receiver
FORC76_RS06515	COG0835	chemotaxis
FORC76_RS06560	COG1085	galactose-1-phosphate uridylyltransferase
FORC76_RS06565	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FORC76_RS06570	COG2017	converts alpha-aldose to the beta-anomer
FORC76_RS06580	COG2200	EAL domain
FORC76_RS06580	COG2199	diguanylate cyclase activity
FORC76_RS06595	COG3527	Alpha-acetolactate decarboxylase
FORC76_RS06630	COG3097	Belongs to the UPF0267 family
FORC76_RS06660	COG1294	oxidase, subunit
FORC76_RS06665	COG1136	(ABC) transporter
FORC76_RS06665	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC76_RS06670	COG0577	efflux transmembrane transporter activity
FORC76_RS06670	COG1136	(ABC) transporter
FORC76_RS06675	COG0577	efflux transmembrane transporter activity
FORC76_RS06675	COG1136	(ABC) transporter
FORC76_RS06700	COG2723	6-phospho-beta-galactosidase activity
FORC76_RS06705	COG1609	Transcriptional regulator
FORC76_RS06710	COG0251	oxidation-reduction process
FORC76_RS06715	COG2731	YhcH YjgK YiaL family protein
FORC76_RS06720	COG0584	glycerophosphoryl diester phosphodiesterase
FORC76_RS06725	COG1349	DNA-binding transcription factor activity
FORC76_RS06730	COG3842	ATPase activity
FORC76_RS06735	COG0395	ABC-type sugar transport system, permease component
FORC76_RS06740	COG1175	transmembrane transport
FORC76_RS06755	COG0811	peptide transport
FORC76_RS06760	COG0811	peptide transport
FORC76_RS06765	COG0848	biopolymer transport protein
FORC76_RS06770	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC76_RS06780	COG1793	dna ligase
FORC76_RS06790	COG0534	Mate efflux family protein
FORC76_RS06800	COG3001	Fructosamine kinase
FORC76_RS06810	COG0791	NLP P60 protein
FORC76_RS06815	COG0840	transmembrane signaling receptor activity
FORC76_RS06825	COG3148	PFAM DTW domain containing protein
FORC76_RS06830	COG1940	carbohydrate kinase activity
FORC76_RS06840	COG0303	'Molybdopterin
FORC76_RS06845	COG0746	molybdenum cofactor guanylyltransferase activity
FORC76_RS06850	COG3842	ATPase activity
FORC76_RS06855	COG4662	Binding-protein-dependent transport system inner membrane component
FORC76_RS06865	COG2204	response regulator
FORC76_RS06870	COG3852	Histidine kinase
FORC76_RS06875	COG0488	(ABC) transporter
FORC76_RS06880	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC76_RS06910	COG3383	formate dehydrogenase (NAD+) activity
FORC76_RS06910	COG3383	formate dehydrogenase (NAD+) activity
FORC76_RS06915	COG0437	4 iron, 4 sulfur cluster binding
FORC76_RS06930	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC76_RS06935	COG1666	GTP binding
FORC76_RS06940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC76_RS06955	COG2996	Protein conserved in bacteria
FORC76_RS06965	COG3008	intermembrane lipid transfer
FORC76_RS06970	COG2995	paraquat-inducible protein a
FORC76_RS06975	COG1132	(ABC) transporter
FORC76_RS06980	COG1956	GAF domain-containing protein
FORC76_RS06985	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FORC76_RS07000	COG0308	aminopeptidase N
FORC76_RS07015	COG0167	dihydroorotate dehydrogenase activity
FORC76_RS07030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC76_RS07030	COG0116	Belongs to the methyltransferase superfamily
FORC76_RS07040	COG0488	(ABC) transporter
FORC76_RS07055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC76_RS07060	COG1067	ATP-dependent peptidase activity
FORC76_RS07065	COG3120	sequence-specific DNA binding
FORC76_RS07080	COG1073	alpha beta
FORC76_RS07080	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FORC76_RS07080	COG3064	Membrane
FORC76_RS07085	COG2994	toxin metabolic process
FORC76_RS07110	COG0784	Response regulator, receiver
FORC76_RS07110	COG2205	protein histidine kinase activity
FORC76_RS07125	COG3278	Belongs to the heme-copper respiratory oxidase family
FORC76_RS07140	COG2010	Cytochrome c
FORC76_RS07150	COG2217	Heavy metal translocating P-type atpase
FORC76_RS07165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC76_RS07170	COG0589	response to stress
FORC76_RS07175	COG0037	tRNA processing
FORC76_RS07195	COG3842	ATPase activity
FORC76_RS07205	COG1177	transmembrane transport
FORC76_RS07215	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC76_RS07230	COG1115	amino acid carrier protein
FORC76_RS07235	COG1280	lysine exporter protein (LysE YggA)
FORC76_RS07260	COG3675	Pfam Lipase (class 3)
FORC76_RS07270	COG3501	Rhs element vgr protein
FORC76_RS07280	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC76_RS07290	COG2814	Major facilitator Superfamily
FORC76_RS07295	COG1566	PFAM secretion protein HlyD family protein
FORC76_RS07300	COG1538	Outer membrane efflux protein
FORC76_RS07310	COG0513	Belongs to the DEAD box helicase family
FORC76_RS07325	COG3290	protein histidine kinase activity
FORC76_RS07325	COG0840	transmembrane signaling receptor activity
FORC76_RS07330	COG0835	chemotaxis
FORC76_RS07335	COG2201	protein-glutamate methylesterase activity
FORC76_RS07345	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC76_RS07350	COG2198	Histidine kinase
FORC76_RS07350	COG0784	Response regulator, receiver
FORC76_RS07350	COG0643	Histidine kinase
FORC76_RS07355	COG2198	Histidine kinase
FORC76_RS07355	COG0643	Histidine kinase
FORC76_RS07365	COG0745	RESPONSE REGULATOR receiver
FORC76_RS07380	COG0415	Belongs to the DNA photolyase family
FORC76_RS07385	COG0477	Major facilitator Superfamily
FORC76_RS07390	COG0583	DNA-binding transcription factor activity
FORC76_RS07400	COG0095	Lipoate-protein ligase
FORC76_RS07405	COG0443	Heat shock 70 kDa protein
FORC76_RS07415	COG1643	Atp-dependent helicase
FORC76_RS07455	COG0443	Heat shock 70 kDa protein
FORC76_RS07460	COG0443	Heat shock 70 kDa protein
FORC76_RS07465	COG3706	GGDEF domain
FORC76_RS07495	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC76_RS07500	COG0602	queuosine metabolic process
FORC76_RS07510	COG0561	phosphatase activity
FORC76_RS07525	COG4597	amino acid ABC transporter
FORC76_RS07530	COG0765	amino acid transport
FORC76_RS07535	COG1126	abc transporter atp-binding protein
FORC76_RS07540	COG0670	Belongs to the BI1 family
FORC76_RS07545	COG2920	part of a sulfur-relay system
FORC76_RS07550	COG1254	Belongs to the acylphosphatase family
FORC76_RS07555	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC76_RS07560	COG3706	GGDEF domain
FORC76_RS07575	COG2205	protein histidine kinase activity
FORC76_RS07575	COG3437	response regulator, receiver
FORC76_RS07575	COG3850	Histidine kinase
FORC76_RS07575	COG4999	Histidine kinase
FORC76_RS07580	COG3437	response regulator, receiver
FORC76_RS07585	COG0625	glutathione transferase activity
FORC76_RS07595	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FORC76_RS07605	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC76_RS07635	COG0372	Belongs to the citrate synthase family
FORC76_RS07640	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC76_RS07675	COG1129	ABC transporter
FORC76_RS07710	COG0745	RESPONSE REGULATOR receiver
FORC76_RS07715	COG5002	protein histidine kinase activity
FORC76_RS07720	COG3713	MltA-interacting MipA family protein
FORC76_RS07725	COG2990	Protein conserved in bacteria
FORC76_RS07735	COG4191	Histidine kinase
FORC76_RS07735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC76_RS07740	COG0471	metal ion transport
FORC76_RS07750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC76_RS07770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC76_RS07780	COG3768	UPF0283 membrane protein
FORC76_RS07785	COG3106	COG3106 Predicted ATPase
FORC76_RS07800	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC76_RS07805	COG0494	nUDIX hydrolase
FORC76_RS07810	COG0814	amino acid
FORC76_RS07820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC76_RS07825	COG0577	efflux transmembrane transporter activity
FORC76_RS07825	COG1136	(ABC) transporter
FORC76_RS07835	COG0720	synthase
FORC76_RS07840	COG0840	transmembrane signaling receptor activity
FORC76_RS07845	COG0017	Asparaginyl-tRNA synthetase
FORC76_RS07850	COG0351	phosphomethylpyrimidine kinase
FORC76_RS07855	COG1448	Aminotransferase
FORC76_RS07870	COG0840	transmembrane signaling receptor activity
FORC76_RS07875	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FORC76_RS07880	COG2943	transferase activity, transferring hexosyl groups
FORC76_RS07885	COG1609	Transcriptional regulator
FORC76_RS07890	COG3394	polysaccharide catabolic process
FORC76_RS07895	COG1486	melibiose metabolic process
FORC76_RS07900	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC76_RS07910	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC76_RS07915	COG0726	polysaccharide deacetylase
FORC76_RS07920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC76_RS07925	COG1846	Transcriptional regulator
FORC76_RS07950	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC76_RS07965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC76_RS07970	COG3108	Peptidase M15
FORC76_RS08000	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC76_RS08010	COG2814	Major facilitator Superfamily
FORC76_RS08020	COG1054	Belongs to the UPF0176 family
FORC76_RS08030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC76_RS08035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC76_RS08040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC76_RS08085	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FORC76_RS08090	COG4139	cobalamin transport
FORC76_RS08095	COG2988	succinylglutamate desuccinylase activity
FORC76_RS08110	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FORC76_RS08115	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FORC76_RS08125	COG1823	symporter activity
FORC76_RS08130	COG2925	Exonuclease
FORC76_RS08135	COG1380	Effector of murein hydrolase LrgA
FORC76_RS08140	COG1346	cytolysis
FORC76_RS08180	COG0776	regulation of translation
FORC76_RS08190	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FORC76_RS08225	COG0322	excinuclease ABC activity
FORC76_RS08230	COG2197	response regulator
FORC76_RS08235	COG0417	DNA replication proofreading
FORC76_RS08250	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC76_RS08255	COG3099	Belongs to the UPF0263 family
FORC76_RS08270	COG1228	amidohydrolase
FORC76_RS08275	COG0010	Belongs to the arginase family
FORC76_RS08280	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FORC76_RS08285	COG2986	histidine ammonia-lyase
FORC76_RS08305	COG0277	FAD linked oxidase domain protein
FORC76_RS08305	COG0247	lactate metabolic process
FORC76_RS08340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FORC76_RS08350	COG0281	malic enzyme
FORC76_RS08360	COG2949	membrane
FORC76_RS08365	COG3706	GGDEF domain
FORC76_RS08370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC76_RS08380	COG0492	ferredoxin-NADP+ reductase activity
FORC76_RS08385	COG4988	ABC transporter
FORC76_RS08390	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC76_RS08395	COG1187	pseudouridine synthase activity
FORC76_RS08400	COG0009	L-threonylcarbamoyladenylate synthase
FORC76_RS08405	COG0613	PHP domain protein
FORC76_RS08415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC76_RS08420	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC76_RS08425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC76_RS08430	COG0135	phosphoribosylanthranilate isomerase activity
FORC76_RS08430	COG0134	indole-3-glycerol-phosphate synthase activity
FORC76_RS08435	COG0133	tryptophan synthase activity
FORC76_RS08440	COG0159	tryptophan synthase activity
FORC76_RS08445	COG1301	dicarboxylic acid transport
FORC76_RS08450	COG1435	thymidine kinase activity
FORC76_RS08455	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FORC76_RS08460	COG1801	Protein of unknown function DUF72
FORC76_RS08465	COG4106	trans-aconitate 2-methyltransferase activity
FORC76_RS08470	COG0500	methyltransferase
FORC76_RS08475	COG4067	protein conserved in archaea
FORC76_RS08475	COG0189	ligase activity
FORC76_RS08490	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FORC76_RS08500	COG3852	Histidine kinase
FORC76_RS08515	COG3070	regulator of competence-specific genes
FORC76_RS08525	COG2431	L-lysine efflux transmembrane transporter activity
FORC76_RS08535	COG0076	glutamate decarboxylase activity
FORC76_RS08540	COG1737	Transcriptional regulator
FORC76_RS08545	COG1454	alcohol dehydrogenase
FORC76_RS08545	COG1012	belongs to the aldehyde dehydrogenase family
FORC76_RS08550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC76_RS08555	COG2985	domain, Protein
FORC76_RS08555	COG3273	potassium ion transport
FORC76_RS08560	COG0542	response to heat
FORC76_RS08565	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FORC76_RS08570	COG1278	Cold shock
FORC76_RS08580	COG1187	pseudouridine synthase activity
FORC76_RS08585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FORC76_RS08585	COG0140	phosphoribosyl-ATP diphosphatase activity
FORC76_RS08590	COG0107	imidazoleglycerol-phosphate synthase activity
FORC76_RS08595	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FORC76_RS08600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FORC76_RS08605	COG0131	Imidazoleglycerol-phosphate dehydratase
FORC76_RS08605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC76_RS08610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC76_RS08615	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FORC76_RS08620	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FORC76_RS08625	COG1757	Na H antiporter
FORC76_RS08630	COG2916	Histone family protein nucleoid-structuring protein H-NS
FORC76_RS08635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC76_RS08640	COG0482	sulfurtransferase activity
FORC76_RS08645	COG2915	High frequency lysogenization protein hflD homolog
FORC76_RS08650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC76_RS08660	COG2268	Band 7 protein
FORC76_RS08670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FORC76_RS08685	COG0300	oxidoreductase activity
FORC76_RS08695	COG0501	Belongs to the peptidase M48B family
FORC76_RS08705	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FORC76_RS08710	COG2226	methyltransferase
FORC76_RS08715	COG0156	8-amino-7-oxononanoate synthase activity
FORC76_RS08720	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FORC76_RS08725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC76_RS08730	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FORC76_RS08735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC76_RS08740	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC76_RS08745	COG0653	protein targeting
FORC76_RS08750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC76_RS08755	COG2199	diguanylate cyclase activity
FORC76_RS08755	COG2203	Gaf domain
FORC76_RS08765	COG4120	Belongs to the binding-protein-dependent transport system permease family
FORC76_RS08775	COG4628	conserved protein (DUF2132)
FORC76_RS08780	COG3092	negative regulation of chromosome organization
FORC76_RS08785	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC76_RS08790	COG0857	belongs to the CobB CobQ family
FORC76_RS08790	COG0280	phosphate acetyltransferase
FORC76_RS08795	COG0435	Glutathione S-transferase
FORC76_RS08800	COG4608	Belongs to the ABC transporter superfamily
FORC76_RS08805	COG0444	Belongs to the ABC transporter superfamily
FORC76_RS08810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC76_RS08835	COG2204	response regulator
FORC76_RS08840	COG5001	Diguanylate cyclase
FORC76_RS08840	COG3300	MHYT domain
FORC76_RS08845	COG4191	Histidine kinase
FORC76_RS08850	COG5002	protein histidine kinase activity
FORC76_RS08860	COG2201	protein-glutamate methylesterase activity
FORC76_RS08875	COG0009	L-threonylcarbamoyladenylate synthase
FORC76_RS08895	COG1881	PFAM PEBP family protein
FORC76_RS08920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC76_RS08925	COG0640	Transcriptional regulator
FORC76_RS08935	COG0454	-acetyltransferase
FORC76_RS08950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC76_RS08960	COG5002	protein histidine kinase activity
FORC76_RS08970	COG3706	GGDEF domain
FORC76_RS08990	COG1946	Acyl-CoA thioesterase
FORC76_RS08995	COG1522	sequence-specific DNA binding
FORC76_RS09005	COG0616	signal peptide processing
FORC76_RS09010	COG1028	Short-chain dehydrogenase reductase Sdr
FORC76_RS09015	COG2983	Belongs to the UPF0260 family
FORC76_RS09025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC76_RS09025	COG1263	PTS System
FORC76_RS09030	COG0084	hydrolase, TatD family'
FORC76_RS09035	COG0470	DNA polymerase III
FORC76_RS09040	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FORC76_RS09045	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC76_RS09050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC76_RS09055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC76_RS09060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC76_RS09065	COG1028	Short-chain dehydrogenase reductase Sdr
FORC76_RS09075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC76_RS09080	COG0416	fatty acid biosynthetic process
FORC76_RS09085	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FORC76_RS09090	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC76_RS09095	COG0424	maF-like protein
FORC76_RS09100	COG0564	pseudouridine synthase activity
FORC76_RS09115	COG1530	ribonuclease E activity
FORC76_RS09125	COG1012	belongs to the aldehyde dehydrogenase family
FORC76_RS09125	COG1454	alcohol dehydrogenase
FORC76_RS09130	COG2095	MarC family integral membrane protein
FORC76_RS09135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC76_RS09140	COG1757	Na H antiporter
FORC76_RS09150	COG3081	Nucleoid-associated protein
FORC76_RS09155	COG3082	Protein of unknown function (DUF1414)
FORC76_RS09160	COG3083	sulfuric ester hydrolase activity
FORC76_RS09175	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC76_RS09180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC76_RS09185	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FORC76_RS09205	COG2853	Lipoprotein
FORC76_RS09215	COG4235	cytochrome complex assembly
FORC76_RS09215	COG3088	subunit of a heme lyase
FORC76_RS09220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC76_RS09225	COG1138	Cytochrome C-type biogenesis protein
FORC76_RS09230	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FORC76_RS09240	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC76_RS09245	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC76_RS09250	COG4133	protoheme IX ABC transporter activity
FORC76_RS09260	COG0835	chemotaxis
FORC76_RS09270	COG1192	Involved in chromosome partitioning
FORC76_RS09275	COG2201	protein-glutamate methylesterase activity
FORC76_RS09280	COG2198	Histidine kinase
FORC76_RS09280	COG0784	Response regulator, receiver
FORC76_RS09280	COG0643	Histidine kinase
FORC76_RS09285	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FORC76_RS09315	COG2062	phosphohistidine phosphatase, SixA
FORC76_RS09320	COG1025	Belongs to the peptidase M16 family
FORC76_RS09330	COG0018	arginyl-trna synthetase
FORC76_RS09355	COG1918	ferrous iron import across plasma membrane
FORC76_RS09360	COG4977	sequence-specific DNA binding
FORC76_RS09365	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FORC76_RS09370	COG1121	(ABC) transporter
FORC76_RS09375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC76_RS09385	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC76_RS09390	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC76_RS09395	COG0567	Dehydrogenase, E1 component
FORC76_RS09405	COG1053	succinate dehydrogenase
FORC76_RS09410	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FORC76_RS09415	COG2009	succinate dehydrogenase
FORC76_RS09425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC76_RS09435	COG0033	Phosphoglucomutase
FORC76_RS09440	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FORC76_RS09445	COG0596	Alpha beta hydrolase
FORC76_RS09460	COG1346	cytolysis
FORC76_RS09470	COG0583	DNA-binding transcription factor activity
FORC76_RS09480	COG0735	belongs to the Fur family
FORC76_RS09485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC76_RS09490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC76_RS09495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC76_RS09500	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC76_RS09500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC76_RS09515	COG3101	peptidyl-lysine hydroxylation
FORC76_RS09520	COG2860	membrane
FORC76_RS09525	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FORC76_RS09530	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC76_RS09535	COG2840	Smr protein MutS2
FORC76_RS09545	COG1684	flagellar biosynthetic protein fliR
FORC76_RS09550	COG1987	bacterial-type flagellum assembly
FORC76_RS09575	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC76_RS09600	COG1317	bacterial-type flagellum organization
FORC76_RS09605	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC76_RS09615	COG1677	Flagellar hook-basal body complex protein FliE
FORC76_RS09635	COG1516	flagellar protein fliS
FORC76_RS09645	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FORC76_RS09650	COG1334	flagellar protein FlaG
FORC76_RS09655	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC76_RS09660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC76_RS09665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC76_RS09670	COG2837	iron assimilation
FORC76_RS09690	COG1393	Belongs to the ArsC family
FORC76_RS09700	COG1876	peptidase activity
FORC76_RS09710	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FORC76_RS09725	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC76_RS09745	COG4783	chaperone-mediated protein folding
FORC76_RS09750	COG1393	Belongs to the ArsC family
FORC76_RS09770	COG2233	PERMEase
FORC76_RS09775	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FORC76_RS09780	COG0737	Belongs to the 5'-nucleotidase family
FORC76_RS09785	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FORC76_RS09790	COG2912	Transglutaminase-like superfamily
FORC76_RS09800	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC76_RS09805	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FORC76_RS09810	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FORC76_RS09815	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FORC76_RS09825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FORC76_RS09830	COG0193	aminoacyl-tRNA hydrolase activity
FORC76_RS09835	COG0012	GTP binding
FORC76_RS09920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC76_RS09925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC76_RS09945	COG3951	Flagellar rod assembly protein muramidase FlgJ
FORC76_RS09945	COG1705	Flagellar rod assembly protein muramidase FlgJ
FORC76_RS09950	COG1706	bacterial-type flagellum-dependent cell motility
FORC76_RS09955	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FORC76_RS09965	COG4787	bacterial-type flagellum-dependent cell motility
FORC76_RS09970	COG1749	Flagellar hook protein flgE
FORC76_RS09985	COG1815	bacterial-type flagellum-dependent cell motility
FORC76_RS09990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC76_RS09995	COG0784	Response regulator, receiver
FORC76_RS09995	COG0835	chemotaxis
FORC76_RS10030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FORC76_RS10030	COG2226	methyltransferase
FORC76_RS10030	COG3433	isochorismatase activity
FORC76_RS10035	COG2375	cellular response to nickel ion
FORC76_RS10040	COG4774	siderophore transport
FORC76_RS10040	COG1629	transport
FORC76_RS10055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC76_RS10060	COG2217	Heavy metal translocating P-type atpase
FORC76_RS10060	COG2608	mercury ion transmembrane transporter activity
FORC76_RS10075	COG3735	TraB family
FORC76_RS10090	COG2840	Smr protein MutS2
FORC76_RS10095	COG1187	pseudouridine synthase activity
FORC76_RS10110	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FORC76_RS10115	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FORC76_RS10120	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC76_RS10125	COG0121	glutamine amidotransferase
FORC76_RS10130	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC76_RS10135	COG1960	acyl-CoA dehydrogenase activity
FORC76_RS10150	COG0328	RNA-DNA hybrid ribonuclease activity
FORC76_RS10155	COG2226	methyltransferase
FORC76_RS10160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC76_RS10170	COG3021	interspecies interaction between organisms
FORC76_RS10175	COG0347	Belongs to the P(II) protein family
FORC76_RS10180	COG3479	Phenolic acid decarboxylase
FORC76_RS10190	COG0037	tRNA processing
FORC76_RS10195	COG0825	malonyl-CoA metabolic process
FORC76_RS10210	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC76_RS10215	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC76_RS10220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC76_RS10225	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC76_RS10230	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FORC76_RS10240	COG0750	zinc metalloprotease
FORC76_RS10245	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FORC76_RS10250	COG0575	Belongs to the CDS family
FORC76_RS10255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FORC76_RS10260	COG0233	cytoplasmic translational termination
FORC76_RS10265	COG0528	UMP kinase activity
FORC76_RS10270	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FORC76_RS10275	COG0052	Belongs to the universal ribosomal protein uS2 family
FORC76_RS10280	COG0024	Methionine aminopeptidase
FORC76_RS10285	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FORC76_RS10295	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC76_RS10300	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FORC76_RS10305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC76_RS10310	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FORC76_RS10325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC76_RS10325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC76_RS10330	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FORC76_RS10335	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FORC76_RS10340	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FORC76_RS10350	COG1073	alpha beta
FORC76_RS10355	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FORC76_RS10360	COG2252	PERMEase
FORC76_RS10365	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC76_RS10370	COG4067	protein conserved in archaea
FORC76_RS10370	COG0189	ligase activity
FORC76_RS10375	COG0189	ligase activity
FORC76_RS10385	COG0733	neurotransmitter:sodium symporter activity
FORC76_RS10390	COG2203	Gaf domain
FORC76_RS10390	COG3706	GGDEF domain
FORC76_RS10390	COG5001	Diguanylate cyclase
FORC76_RS10390	COG4251	negative regulation of phosphorylation
FORC76_RS10415	COG1477	protein flavinylation
FORC76_RS10420	COG2871	sodium ion transport
FORC76_RS10425	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC76_RS10430	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC76_RS10435	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC76_RS10440	COG1805	sodium ion transport
FORC76_RS10445	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC76_RS10450	COG0271	Belongs to the BolA IbaG family
FORC76_RS10455	COG2813	Specifically methylates the guanine in position
FORC76_RS10480	COG5433	transposase activity
FORC76_RS10495	COG1595	DNA-templated transcription, initiation
FORC76_RS10510	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC76_RS10515	COG0693	protein deglycase activity
FORC76_RS10520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC76_RS10525	COG2166	iron-sulfur cluster assembly
FORC76_RS10530	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC76_RS10535	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FORC76_RS10545	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC76_RS10545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC76_RS10555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC76_RS10560	COG1074	ATP-dependent DNA helicase activity
FORC76_RS10565	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FORC76_RS10580	COG3141	response to X-ray
FORC76_RS10585	COG2171	N-acyltransferase activity
FORC76_RS10600	COG0189	ligase activity
FORC76_RS10600	COG0569	domain protein
FORC76_RS10615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC76_RS10620	COG1609	Transcriptional regulator
FORC76_RS10625	COG3250	beta-galactosidase activity
FORC76_RS10645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC76_RS10650	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC76_RS10660	COG0560	Phosphoserine phosphatase
FORC76_RS10670	COG3385	transposase activity
FORC76_RS10675	COG0813	purine-nucleoside phosphorylase activity
FORC76_RS10680	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FORC76_RS10685	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC76_RS10690	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FORC76_RS10705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC76_RS10710	COG0084	hydrolase, TatD family'
FORC76_RS10715	COG3022	response to hydroperoxide
FORC76_RS10720	COG1115	amino acid carrier protein
FORC76_RS10735	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FORC76_RS10740	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FORC76_RS10745	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FORC76_RS10750	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FORC76_RS10755	COG0083	homoserine kinase activity
FORC76_RS10775	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC76_RS10785	COG0745	RESPONSE REGULATOR receiver
FORC76_RS10790	COG5002	protein histidine kinase activity
FORC76_RS10790	COG2198	Histidine kinase
FORC76_RS10790	COG0784	Response regulator, receiver
FORC76_RS10795	COG5001	Diguanylate cyclase
FORC76_RS10795	COG3706	GGDEF domain
FORC76_RS10795	COG4251	negative regulation of phosphorylation
FORC76_RS10795	COG2203	Gaf domain
FORC76_RS10800	COG1242	4 iron, 4 sulfur cluster binding
FORC76_RS10805	COG0070	glutamate synthase
FORC76_RS10805	COG0069	glutamate synthase activity
FORC76_RS10805	COG0067	glutamate synthase
FORC76_RS10815	COG0069	glutamate synthase activity
FORC76_RS10815	COG0067	glutamate synthase
FORC76_RS10815	COG0070	glutamate synthase
FORC76_RS10820	COG0493	'glutamate synthase
FORC76_RS10830	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC76_RS10840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC76_RS10845	COG2860	membrane
FORC76_RS10850	COG0583	DNA-binding transcription factor activity
FORC76_RS10855	COG0730	response to heat
FORC76_RS10875	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FORC76_RS10880	COG0505	Belongs to the CarA family
FORC76_RS10890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FORC76_RS10895	COG0494	nUDIX hydrolase
FORC76_RS10900	COG0653	protein targeting
FORC76_RS10910	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FORC76_RS10915	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC76_RS10920	COG0849	cell division
FORC76_RS10925	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FORC76_RS10930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC76_RS10935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FORC76_RS10940	COG0772	Belongs to the SEDS family
FORC76_RS10945	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FORC76_RS10955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC76_RS10960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FORC76_RS10965	COG0768	penicillin binding
FORC76_RS10970	COG3116	cell division
FORC76_RS10985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC76_RS10990	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC76_RS10995	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FORC76_RS11000	COG2186	Transcriptional regulator
FORC76_RS11015	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC76_RS11020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC76_RS11025	COG4974	Belongs to the 'phage' integrase family
FORC76_RS11030	COG0716	FMN binding
FORC76_RS11040	COG0157	Belongs to the NadC ModD family
FORC76_RS11050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC76_RS11055	COG1459	type II secretion system
FORC76_RS11065	COG0237	dephospho-CoA kinase activity
FORC76_RS11070	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FORC76_RS11080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC76_RS11085	COG0187	DNA topoisomerase II activity
FORC76_RS11090	COG3150	esterase
FORC76_RS11100	COG5433	transposase activity
FORC76_RS11110	COG3151	Protein conserved in bacteria
FORC76_RS11115	COG0494	nUDIX hydrolase
FORC76_RS11120	COG1538	Outer membrane efflux protein
FORC76_RS11130	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FORC76_RS11140	COG3025	triphosphatase activity
FORC76_RS11145	COG1392	Phosphate transport regulator
FORC76_RS11150	COG0306	phosphate transporter
FORC76_RS11155	COG4991	sh3 domain protein
FORC76_RS11175	COG0148	phosphopyruvate hydratase activity
FORC76_RS11180	COG0504	CTP synthase activity
FORC76_RS11185	COG3956	TIGRFAM MazG family protein
FORC76_RS11190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC76_RS11200	COG4999	Histidine kinase
FORC76_RS11200	COG3850	Histidine kinase
FORC76_RS11200	COG3437	response regulator, receiver
FORC76_RS11200	COG2205	protein histidine kinase activity
FORC76_RS11220	COG0736	holo-[acyl-carrier-protein] synthase activity
FORC76_RS11225	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FORC76_RS11230	COG1381	Involved in DNA repair and RecF pathway recombination
FORC76_RS11235	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC76_RS11240	COG0571	ribonuclease III activity
FORC76_RS11250	COG0481	GTPase activity
FORC76_RS11255	COG3086	response to oxidative stress
FORC76_RS11270	COG1595	DNA-templated transcription, initiation
FORC76_RS11280	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC76_RS11290	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FORC76_RS11305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC76_RS11310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC76_RS11315	COG3079	Belongs to the UPF0149 family
FORC76_RS11320	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FORC76_RS11330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC76_RS11335	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FORC76_RS11345	COG0440	acetolactate synthase activity
FORC76_RS11350	COG0028	Belongs to the TPP enzyme family
FORC76_RS11355	COG1022	Amp-dependent synthetase and ligase
FORC76_RS11360	COG0583	DNA-binding transcription factor activity
FORC76_RS11380	COG0473	3-isopropylmalate dehydrogenase activity
FORC76_RS11385	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FORC76_RS11390	COG0066	3-isopropylmalate dehydratase activity
FORC76_RS11395	COG3385	transposase activity
FORC76_RS11490	COG0582	viral genome integration into host DNA
FORC76_RS11510	COG0795	lipopolysaccharide-transporting ATPase activity
FORC76_RS11515	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC76_RS11520	COG2927	DNA polymerase III (CHI subunit)
FORC76_RS11525	COG0525	valine-tRNA ligase activity
FORC76_RS11530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC76_RS11535	COG0564	pseudouridine synthase activity
FORC76_RS11545	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC76_RS11560	COG0540	Belongs to the ATCase OTCase family
FORC76_RS11570	COG0251	oxidation-reduction process
FORC76_RS11585	COG5007	Belongs to the BolA IbaG family
FORC76_RS11595	COG2854	intermembrane phospholipid transfer
FORC76_RS11600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC76_RS11605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC76_RS11610	COG1127	ABC transporter
FORC76_RS11625	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORC76_RS11625	COG0517	IMP dehydrogenase activity
FORC76_RS11640	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FORC76_RS11645	COG1137	ATPase activity
FORC76_RS11655	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC76_RS11660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC76_RS11665	COG1660	Displays ATPase and GTPase activities
FORC76_RS11670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC76_RS11675	COG2239	Acts as a magnesium transporter
FORC76_RS11680	COG0312	modulator of DNA gyrase
FORC76_RS11685	COG3028	Belongs to the UPF0307 family
FORC76_RS11690	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FORC76_RS11695	COG1178	ABC-type Fe3 transport system permease component
FORC76_RS11705	COG0163	prenyltransferase activity
FORC76_RS11710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC76_RS11725	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FORC76_RS11730	COG2105	PFAM AIG2 family protein
FORC76_RS11740	COG0729	surface antigen
FORC76_RS11745	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC76_RS11750	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC76_RS11765	COG1136	(ABC) transporter
FORC76_RS11785	COG0529	Catalyzes the synthesis of activated sulfate
FORC76_RS11790	COG2895	sulfate adenylyltransferase (ATP) activity
FORC76_RS11795	COG0175	sulfate reduction
FORC76_RS11800	COG1648	precorrin-2 dehydrogenase activity
FORC76_RS11800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC76_RS11810	COG0737	Belongs to the 5'-nucleotidase family
FORC76_RS11820	COG0513	Belongs to the DEAD box helicase family
FORC76_RS11825	COG2153	protein acetylation
FORC76_RS11830	COG0697	spore germination
FORC76_RS11835	COG3266	domain, Protein
FORC76_RS11835	COG3061	Opacity-associated protein A
FORC76_RS11840	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC76_RS11850	COG0203	ribosomal protein L17
FORC76_RS11855	COG0202	RNA polymerase activity
FORC76_RS11860	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FORC76_RS11865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FORC76_RS11870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FORC76_RS11875	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC76_RS11880	COG0201	protein transport
FORC76_RS11890	COG1841	ribosomal large subunit assembly
FORC76_RS11895	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FORC76_RS11900	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FORC76_RS11905	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FORC76_RS11910	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FORC76_RS11915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FORC76_RS11920	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FORC76_RS11925	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FORC76_RS11930	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FORC76_RS11935	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FORC76_RS11940	COG0255	Belongs to the universal ribosomal protein uL29 family
FORC76_RS11945	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FORC76_RS11950	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FORC76_RS11955	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FORC76_RS11960	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FORC76_RS11965	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FORC76_RS11970	COG0089	rRNA binding
FORC76_RS11975	COG0088	Forms part of the polypeptide exit tunnel
FORC76_RS11980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FORC76_RS11985	COG0051	transcription antitermination factor activity, RNA binding
FORC76_RS11990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC76_RS11995	COG0557	exoribonuclease II activity
FORC76_RS12005	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FORC76_RS12015	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC76_RS12025	COG1047	Peptidyl-prolyl cis-trans
FORC76_RS12040	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC76_RS12045	COG0488	(ABC) transporter
FORC76_RS12055	COG0429	hydrolase of the alpha beta-hydrolase fold
FORC76_RS12065	COG3954	Phosphoribulokinase
FORC76_RS12080	COG1012	belongs to the aldehyde dehydrogenase family
FORC76_RS12090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC76_RS12100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC76_RS12115	COG0180	Tryptophanyl-tRNA synthetase
FORC76_RS12120	COG0546	phosphoglycolate phosphatase activity
FORC76_RS12125	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC76_RS12130	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FORC76_RS12140	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FORC76_RS12145	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FORC76_RS12175	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC76_RS12185	COG0678	peroxiredoxin activity
FORC76_RS12185	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC76_RS12190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC76_RS12200	COG0165	Argininosuccinate lyase
FORC76_RS12205	COG0137	argininosuccinate synthase activity
FORC76_RS12210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC76_RS12215	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FORC76_RS12220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC76_RS12225	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FORC76_RS12235	COG1045	serine acetyltransferase
FORC76_RS12240	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FORC76_RS12245	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FORC76_RS12250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC76_RS12255	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FORC76_RS12260	COG1053	succinate dehydrogenase
FORC76_RS12265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC76_RS12270	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC76_RS12280	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC76_RS12285	COG1509	lysine 2,3-aminomutase activity
FORC76_RS12295	COG0459	protein refolding
FORC76_RS12300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC76_RS12325	COG0149	triose-phosphate isomerase activity
FORC76_RS12330	COG0534	Mate efflux family protein
FORC76_RS12335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC76_RS12340	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC76_RS12345	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FORC76_RS12350	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FORC76_RS12355	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC76_RS12360	COG1609	Transcriptional regulator
FORC76_RS12365	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC76_RS12370	COG0254	rRNA binding
FORC76_RS12375	COG0281	malic enzyme
FORC76_RS12380	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FORC76_RS12385	COG0626	cystathionine gamma-synthase activity
FORC76_RS12390	COG0460	homoserine dehydrogenase
FORC76_RS12390	COG0527	aspartate kinase activity
FORC76_RS12395	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC76_RS12400	COG3074	FtsZ-dependent cytokinesis
FORC76_RS12405	COG1494	fructose-1,6-bisphosphatase
FORC76_RS12410	COG0205	6-phosphofructokinase activity
FORC76_RS12415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC76_RS12425	COG0745	RESPONSE REGULATOR receiver
FORC76_RS12430	COG2205	protein histidine kinase activity
FORC76_RS12440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC76_RS12445	COG3030	protein affecting phage T7 exclusion by the F plasmid
FORC76_RS12450	COG3706	GGDEF domain
FORC76_RS12455	COG1027	Aspartate ammonia-lyase
FORC76_RS12460	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC76_RS12470	COG4232	protein-disulfide reductase activity
FORC76_RS12490	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC76_RS12495	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FORC76_RS12500	COG0194	GDP metabolic process
FORC76_RS12505	COG1758	RNA polymerase activity
FORC76_RS12510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC76_RS12515	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC76_RS12520	COG2233	PERMEase
FORC76_RS12535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC76_RS12540	COG2183	response to ionizing radiation
FORC76_RS12550	COG0596	Alpha beta hydrolase
FORC76_RS12555	COG1040	competence protein
FORC76_RS12565	COG0494	nUDIX hydrolase
FORC76_RS12570	COG1218	3'(2'),5'-bisphosphate nucleotidase
FORC76_RS12580	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC76_RS12585	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC76_RS12590	COG3156	type II secretion system protein K
FORC76_RS12595	COG4795	General secretion pathway protein
FORC76_RS12600	COG2165	general secretion pathway protein
FORC76_RS12605	COG2165	general secretion pathway protein
FORC76_RS12610	COG2165	general secretion pathway protein
FORC76_RS12615	COG1459	type II secretion system
FORC76_RS12620	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC76_RS12630	COG3031	protein transport across the cell outer membrane
FORC76_RS12635	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC76_RS12640	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FORC76_RS12645	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FORC76_RS12660	COG1490	D-aminoacyl-tRNA deacylase activity
FORC76_RS12665	COG1295	ribonuclease BN
FORC76_RS12675	COG1217	gtp-binding protein TYPA
FORC76_RS12685	COG0174	glutamine synthetase
FORC76_RS12695	COG3852	Histidine kinase
FORC76_RS12705	COG3300	MHYT domain
FORC76_RS12705	COG5001	Diguanylate cyclase
FORC76_RS12710	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FORC76_RS12780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FORC76_RS12785	COG1404	Belongs to the peptidase S8 family
FORC76_RS12795	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC76_RS12810	COG1609	Transcriptional regulator
FORC76_RS12820	COG2017	converts alpha-aldose to the beta-anomer
FORC76_RS12825	COG3459	Glycosyltransferase 36 associated
FORC76_RS12830	COG3842	ATPase activity
FORC76_RS12835	COG2723	6-phospho-beta-galactosidase activity
FORC76_RS12840	COG0395	ABC-type sugar transport system, permease component
FORC76_RS12845	COG1175	transmembrane transport
FORC76_RS12855	COG1609	Transcriptional regulator
FORC76_RS12860	COG0840	transmembrane signaling receptor activity
FORC76_RS12885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC76_RS12890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC76_RS12895	COG2177	Part of the ABC transporter FtsEX involved in
FORC76_RS12900	COG2884	Cell division ATP-binding protein ftsE
FORC76_RS12905	COG0552	protein localization to endoplasmic reticulum
FORC76_RS12910	COG0742	ribosomal rna small subunit methyltransferase
FORC76_RS12945	COG0783	Belongs to the Dps family
FORC76_RS12950	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC76_RS12955	COG1280	lysine exporter protein (LysE YggA)
FORC76_RS12960	COG2267	carboxylic ester hydrolase activity
FORC76_RS12965	COG0561	phosphatase activity
FORC76_RS12980	COG2200	EAL domain
FORC76_RS12980	COG3287	FIST C domain
FORC76_RS12980	COG2199	diguanylate cyclase activity
FORC76_RS12985	COG1011	Hydrolase
FORC76_RS12990	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FORC76_RS13000	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FORC76_RS13005	COG0019	diaminopimelate decarboxylase activity
FORC76_RS13015	COG1965	Belongs to the frataxin family
FORC76_RS13020	COG3072	Adenylate cyclase
FORC76_RS13030	COG0181	hydroxymethylbilane synthase activity
FORC76_RS13035	COG1587	Uroporphyrinogen-III synthase
FORC76_RS13040	COG2959	enzyme of heme biosynthesis
FORC76_RS13045	COG3071	HemY protein
FORC76_RS13060	COG3078	GTPase activator activity
FORC76_RS13080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC76_RS13080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC76_RS13095	COG0084	hydrolase, TatD family'
FORC76_RS13105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC76_RS13120	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC76_RS13130	COG3161	chorismate lyase activity
FORC76_RS13135	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FORC76_RS13140	COG2937	Belongs to the GPAT DAPAT family
FORC76_RS13150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC76_RS13160	COG0534	Mate efflux family protein
FORC76_RS13165	COG1858	cytochrome C peroxidase
FORC76_RS13170	COG0805	protein transport
FORC76_RS13175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC76_RS13180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC76_RS13195	COG2226	methyltransferase
FORC76_RS13200	COG1322	Protein conserved in bacteria
FORC76_RS13245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC76_RS13285	COG2205	protein histidine kinase activity
FORC76_RS13290	COG0745	RESPONSE REGULATOR receiver
FORC76_RS13300	COG0569	domain protein
FORC76_RS13305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC76_RS13345	COG2081	HI0933 family
FORC76_RS13355	COG1528	Iron-storage protein
FORC76_RS13365	COG0589	response to stress
FORC76_RS13385	COG5002	protein histidine kinase activity
FORC76_RS13385	COG5001	Diguanylate cyclase
FORC76_RS13390	COG1522	sequence-specific DNA binding
FORC76_RS13410	COG0006	proline dipeptidase activity
FORC76_RS13410	COG0006	proline dipeptidase activity
FORC76_RS13415	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FORC76_RS13420	COG2022	thiamine diphosphate biosynthetic process
FORC76_RS13425	COG2104	thiamine diphosphate biosynthetic process
FORC76_RS13430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC76_RS13440	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FORC76_RS13445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FORC76_RS13485	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC76_RS13495	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORC76_RS13500	COG0408	coproporphyrinogen oxidase activity
FORC76_RS13505	COG0009	L-threonylcarbamoyladenylate synthase
FORC76_RS13510	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC76_RS13515	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FORC76_RS13520	COG0551	DNA topoisomerase type I activity
FORC76_RS13525	COG2922	Belongs to the Smg family
FORC76_RS13530	COG0758	DNA mediated transformation
FORC76_RS13535	COG1652	LysM domain
FORC76_RS13540	COG0242	peptide deformylase activity
FORC76_RS13545	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC76_RS13550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC76_RS13550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC76_RS13555	COG0569	domain protein
FORC76_RS13560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC76_RS13570	COG1272	protein, Hemolysin III
FORC76_RS13575	COG4326	sporulation control protein
FORC76_RS13585	COG3084	Protein conserved in bacteria
FORC76_RS13595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC76_RS13600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC76_RS13605	COG0606	chelatase, subunit chli
FORC76_RS13620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC76_RS13625	COG0129	dihydroxy-acid dehydratase activity
FORC76_RS13645	COG0425	Belongs to the sulfur carrier protein TusA family
FORC76_RS13660	COG2119	membrane
FORC76_RS13665	COG0752	glycyl-tRNA synthetase alpha subunit
FORC76_RS13670	COG0751	glycine-tRNA ligase activity
FORC76_RS13675	COG3977	Valine--pyruvate aminotransferase
FORC76_RS13680	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC76_RS13685	COG3385	transposase activity
FORC76_RS13690	COG0706	membrane insertase activity
FORC76_RS13700	COG0594	ribonuclease P activity
FORC76_RS13705	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FORC76_RS13710	COG1126	abc transporter atp-binding protein
FORC76_RS13760	COG0217	transcriptional regulatory protein
FORC76_RS13765	COG2084	Dehydrogenase
FORC76_RS13785	COG2909	trisaccharide binding
FORC76_RS13790	COG0058	SHG alpha-glucan phosphorylase activity
FORC76_RS13795	COG1640	4-alpha-glucanotransferase
FORC76_RS13800	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FORC76_RS13810	COG3501	Rhs element vgr protein
FORC76_RS13860	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC76_RS13890	COG0671	phosphoesterase, PA-phosphatase related
FORC76_RS13895	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FORC76_RS13905	COG1999	signal sequence binding
FORC76_RS13920	COG0786	glutamate:sodium symporter activity
FORC76_RS13955	COG0813	purine-nucleoside phosphorylase activity
FORC76_RS13965	COG3272	Protein of unknown function (DUF1722)
FORC76_RS13975	COG0415	Belongs to the DNA photolyase family
FORC76_RS13980	COG1388	LysM domain
FORC76_RS13980	COG1376	ErfK ybiS ycfS ynhG family protein
FORC76_RS13990	COG0513	Belongs to the DEAD box helicase family
FORC76_RS13995	COG1770	oligopeptidase
FORC76_RS14025	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC76_RS14030	COG0573	inorganic phosphate transmembrane transporter activity
FORC76_RS14035	COG0581	inorganic phosphate transmembrane transporter activity
FORC76_RS14040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC76_RS14055	COG3314	Sporulation integral membrane protein YlbJ
FORC76_RS14060	COG0659	secondary active sulfate transmembrane transporter activity
FORC76_RS14075	COG0739	heme binding
FORC76_RS14085	COG0583	DNA-binding transcription factor activity
FORC76_RS14090	COG2814	Major facilitator Superfamily
FORC76_RS14110	COG0697	spore germination
FORC76_RS14115	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC76_RS14120	COG1764	response to oxidative stress
FORC76_RS14125	COG1846	Transcriptional regulator
FORC76_RS14145	COG2207	Transcriptional regulator
FORC76_RS14150	COG1280	lysine exporter protein (LysE YggA)
FORC76_RS14160	COG1902	pentaerythritol trinitrate reductase activity
FORC76_RS14170	COG1132	(ABC) transporter
FORC76_RS14180	COG0513	Belongs to the DEAD box helicase family
FORC76_RS14190	COG0840	transmembrane signaling receptor activity
FORC76_RS14200	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FORC76_RS14215	COG1620	l-lactate permease
FORC76_RS14220	COG0583	DNA-binding transcription factor activity
FORC76_RS14240	COG4172	Belongs to the ABC transporter superfamily
FORC76_RS14250	COG1067	ATP-dependent peptidase activity
FORC76_RS14255	COG2211	Major facilitator Superfamily
FORC76_RS14265	COG3123	guanosine phosphorylase activity
FORC76_RS14270	COG1741	Belongs to the pirin family
FORC76_RS14280	COG5001	Diguanylate cyclase
FORC76_RS14285	COG0583	DNA-binding transcription factor activity
FORC76_RS14325	COG3706	GGDEF domain
FORC76_RS14330	COG1846	Transcriptional regulator
FORC76_RS14335	COG0784	Response regulator, receiver
FORC76_RS14335	COG0835	chemotaxis
FORC76_RS14340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC76_RS14350	COG0393	Putative heavy-metal-binding
FORC76_RS14365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC76_RS14370	COG3842	ATPase activity
FORC76_RS14385	COG1175	transmembrane transport
FORC76_RS14390	COG3833	ABC-type maltose transport systems, permease component
FORC76_RS14405	COG1349	DNA-binding transcription factor activity
FORC76_RS14440	COG1278	Cold shock
FORC76_RS14445	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC76_RS14450	COG2354	Protein conserved in bacteria
FORC76_RS14455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC76_RS14460	COG0418	dihydroorotase activity
FORC76_RS14465	COG0633	Ferredoxin
FORC76_RS14465	COG3217	Mosc domain protein beta barrel domain protein
FORC76_RS14465	COG0633	Ferredoxin
FORC76_RS14465	COG3217	Mosc domain protein beta barrel domain protein
FORC76_RS14500	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FORC76_RS14505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC76_RS14510	COG4558	Periplasmic binding protein
FORC76_RS14515	COG0848	biopolymer transport protein
FORC76_RS14520	COG0811	peptide transport
FORC76_RS14525	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC76_RS14535	COG3721	Heme iron utilization protein
FORC76_RS14540	COG0748	coenzyme F420 binding
FORC76_RS14550	COG3835	regulator
FORC76_RS14555	COG2610	gluconate transmembrane transporter activity
FORC76_RS14560	COG1929	Belongs to the glycerate kinase type-1 family
FORC76_RS14585	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FORC76_RS14590	COG0363	glucosamine-6-phosphate deaminase activity
FORC76_RS14595	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC76_RS14600	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC76_RS14605	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC76_RS14625	COG0346	lactoylglutathione lyase activity
FORC76_RS14635	COG2873	o-acetylhomoserine
FORC76_RS14645	COG1063	alcohol dehydrogenase
FORC76_RS14650	COG2771	luxR family
FORC76_RS14650	COG2200	EAL domain
FORC76_RS14660	COG1278	Cold shock
FORC76_RS14665	COG0557	exoribonuclease II activity
FORC76_RS14670	COG1686	Belongs to the peptidase S11 family
FORC76_RS14680	COG3047	cAMP biosynthetic process
FORC76_RS14690	COG3227	Zinc metalloprotease (Elastase)
FORC76_RS14700	COG2267	carboxylic ester hydrolase activity
FORC76_RS14705	COG2067	long-chain fatty acid transport protein
FORC76_RS14715	COG0366	Alpha amylase catalytic
FORC76_RS14720	COG4989	oxidoreductase activity
FORC76_RS14740	COG0531	amino acid
FORC76_RS14770	COG1765	OsmC-like protein
FORC76_RS14775	COG1253	flavin adenine dinucleotide binding
FORC76_RS14800	COG2264	protein methyltransferase activity
FORC76_RS14815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC76_RS14820	COG3186	Phenylalanine-4-hydroxylase
FORC76_RS14825	COG2154	pterin-4-alpha-carbinolamine dehydratase
FORC76_RS14830	COG0456	acetyltransferase
FORC76_RS14835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC76_RS14840	COG0662	Cupin 2, conserved barrel domain protein
FORC76_RS14845	COG0527	aspartate kinase activity
FORC76_RS14855	COG0459	protein refolding
FORC76_RS14860	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC76_RS14865	COG2239	Acts as a magnesium transporter
FORC76_RS14875	COG1166	arginine decarboxylase activity
FORC76_RS14885	COG3046	protein related to deoxyribodipyrimidine photolyase
FORC76_RS14895	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC76_RS14910	COG0513	Belongs to the DEAD box helicase family
FORC76_RS14920	COG1368	sulfuric ester hydrolase activity
FORC76_RS14925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC76_RS14955	COG0484	heat shock protein binding
FORC76_RS14970	COG5001	Diguanylate cyclase
FORC76_RS14970	COG1716	ATPase activity
FORC76_RS14975	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC76_RS14985	COG4181	ATPase activity
FORC76_RS14990	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FORC76_RS15005	COG1984	allophanate hydrolase subunit 2
FORC76_RS15015	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FORC76_RS15025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC76_RS15030	COG0840	transmembrane signaling receptor activity
FORC76_RS15035	COG0814	amino acid
FORC76_RS15045	COG0513	Belongs to the DEAD box helicase family
FORC76_RS15050	COG1309	transcriptional regulator
FORC76_RS15060	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC76_RS15065	COG0494	nUDIX hydrolase
FORC76_RS15075	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FORC76_RS15080	COG1126	abc transporter atp-binding protein
FORC76_RS15085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC76_RS15090	COG4215	(ABC) transporter
FORC76_RS15095	COG4160	amino acid transport
FORC76_RS15120	COG3118	belongs to the thioredoxin family
FORC76_RS15125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC76_RS15130	COG0247	lactate metabolic process
FORC76_RS15140	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC76_RS15145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC76_RS15150	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FORC76_RS15165	COG2926	Belongs to the UPF0265 family
FORC76_RS15175	COG3132	Protein of unknown function, DUF480
FORC76_RS15180	COG2827	Endonuclease containing a URI domain
FORC76_RS15190	COG1879	ABC-type sugar transport system periplasmic component
FORC76_RS15195	COG0784	Response regulator, receiver
FORC76_RS15195	COG5002	protein histidine kinase activity
FORC76_RS15240	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC76_RS15275	COG4191	Histidine kinase
FORC76_RS15280	COG1289	transmembrane transporter activity
FORC76_RS15285	COG0210	DNA helicase
FORC76_RS15290	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC76_RS15295	COG1335	isochorismatase
FORC76_RS15300	COG1803	Methylglyoxal synthase
FORC76_RS15305	COG1879	ABC-type sugar transport system periplasmic component
FORC76_RS15310	COG0784	Response regulator, receiver
FORC76_RS15310	COG2205	protein histidine kinase activity
FORC76_RS15310	COG2198	Histidine kinase
FORC76_RS15315	COG0469	pyruvate kinase activity
FORC76_RS15320	COG2271	Major facilitator Superfamily
FORC76_RS15330	COG4191	Histidine kinase
FORC76_RS15345	COG1979	alcohol dehydrogenase
FORC76_RS15355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC76_RS15375	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC76_RS15380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC76_RS15390	COG0183	Belongs to the thiolase family
FORC76_RS15400	COG3243	poly(R)-hydroxyalkanoic acid synthase
FORC76_RS15405	COG3842	ATPase activity
FORC76_RS15415	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC76_RS15420	COG2271	Major facilitator Superfamily
FORC76_RS15425	COG3851	Histidine kinase
FORC76_RS15430	COG2197	response regulator
FORC76_RS15450	COG0243	molybdopterin cofactor binding
FORC76_RS15460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC76_RS15465	COG3850	Histidine kinase
FORC76_RS15470	COG2197	response regulator
FORC76_RS15475	COG1760	l-serine dehydratase
FORC76_RS15480	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC76_RS15495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC76_RS15500	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC76_RS15515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC76_RS15520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC76_RS15525	COG1621	beta-fructofuranosidase activity
FORC76_RS15530	COG1609	Transcriptional regulator
FORC76_RS15535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC76_RS15535	COG1263	PTS System
FORC76_RS15550	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC76_RS15595	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FORC76_RS15600	COG0583	DNA-binding transcription factor activity
FORC76_RS15625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC76_RS15650	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC76_RS15665	COG2390	Transcriptional regulator
FORC76_RS15670	COG2897	thiosulfate sulfurtransferase activity
FORC76_RS15680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC76_RS15690	COG0302	gtp cyclohydrolase
FORC76_RS15695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC76_RS15695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC76_RS15700	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FORC76_RS15705	COG1970	mechanosensitive ion channel activity
FORC76_RS15710	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FORC76_RS15720	COG1011	Hydrolase
FORC76_RS15740	COG3833	ABC-type maltose transport systems, permease component
FORC76_RS15745	COG1175	transmembrane transport
FORC76_RS15760	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC76_RS15770	COG3842	ATPase activity
FORC76_RS15780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC76_RS15785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC76_RS15790	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC76_RS15825	COG4166	transmembrane transport
FORC76_RS15830	COG4174	ABC transporter (Permease)
FORC76_RS15835	COG4239	(ABC) transporter, permease
FORC76_RS15840	COG4172	Belongs to the ABC transporter superfamily
FORC76_RS15845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FORC76_RS15860	COG0625	glutathione transferase activity
FORC76_RS15885	COG2050	protein possibly involved in aromatic compounds catabolism
FORC76_RS15900	COG1629	transport
FORC76_RS15900	COG4771	TonB-dependent receptor
FORC76_RS15905	COG0583	DNA-binding transcription factor activity
FORC76_RS15910	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC76_RS15910	COG1042	CoA-binding domain protein
FORC76_RS15910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC76_RS15930	COG0023	Translation Initiation Factor
FORC76_RS15935	COG3140	Belongs to the UPF0181 family
FORC76_RS15950	COG0745	RESPONSE REGULATOR receiver
FORC76_RS15960	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FORC76_RS15965	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FORC76_RS15980	COG3706	GGDEF domain
FORC76_RS16030	COG2824	Alkylphosphonate utilization operon protein PhnA
FORC76_RS16045	COG0737	Belongs to the 5'-nucleotidase family
FORC76_RS16050	COG3593	DNA synthesis involved in DNA repair
FORC76_RS16060	COG0583	DNA-binding transcription factor activity
FORC76_RS16065	COG2116	formate transmembrane transporter activity
FORC76_RS16075	COG3038	cytochrome b561
FORC76_RS16085	COG2200	EAL domain
FORC76_RS16095	COG0586	Pfam SNARE associated Golgi protein
FORC76_RS16105	COG0523	cobalamin synthesis protein
FORC76_RS16110	COG0038	chloride channel
FORC76_RS16120	COG0156	8-amino-7-oxononanoate synthase activity
FORC76_RS16125	COG0784	Response regulator, receiver
FORC76_RS16125	COG2205	protein histidine kinase activity
FORC76_RS16130	COG0419	ATPase involved in DNA repair
FORC76_RS16135	COG0420	3'-5' exonuclease activity
FORC76_RS16140	COG1609	Transcriptional regulator
FORC76_RS16145	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC76_RS16145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC76_RS16150	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC76_RS16155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC76_RS16155	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FORC76_RS16155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC76_RS16160	COG0189	ligase activity
FORC76_RS16160	COG4067	protein conserved in archaea
FORC76_RS16170	COG0602	queuosine metabolic process
FORC76_RS16175	COG1328	CTP reductase activity
FORC76_RS16185	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FORC76_RS16245	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC76_RS16275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC76_RS16345	COG5642	Protein of unknown function (DUF2384)
FORC76_RS16385	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC76_RS16390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC76_RS16625	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC76_RS16680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC76_RS16715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC76_RS16775	COG0454	-acetyltransferase
FORC76_RS16795	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC76_RS16815	COG0346	lactoylglutathione lyase activity
FORC76_RS16950	COG0384	phenazine biosynthesis protein PhzF
FORC76_RS16985	COG0384	phenazine biosynthesis protein PhzF
FORC76_RS17100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC76_RS17130	COG0519	Catalyzes the synthesis of GMP from XMP
FORC76_RS17185	COG3041	Addiction module toxin RelE StbE family
FORC76_RS17215	COG4977	sequence-specific DNA binding
FORC76_RS17225	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC76_RS17280	COG0384	phenazine biosynthesis protein PhzF
FORC76_RS17405	COG0384	phenazine biosynthesis protein PhzF
FORC76_RS17540	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC76_RS17560	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FORC76_RS17565	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FORC76_RS17580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FORC76_RS17590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC76_RS17595	COG0509	glycine decarboxylation via glycine cleavage system
FORC76_RS17600	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC76_RS17600	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC76_RS17620	COG1686	Belongs to the peptidase S11 family
FORC76_RS17655	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC76_RS17670	COG5002	protein histidine kinase activity
FORC76_RS17675	COG0745	RESPONSE REGULATOR receiver
FORC76_RS17720	COG0561	phosphatase activity
FORC76_RS17725	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FORC76_RS17730	COG3623	hexulose-6-phosphate isomerase
FORC76_RS17740	COG0745	RESPONSE REGULATOR receiver
FORC76_RS17755	COG0583	DNA-binding transcription factor activity
FORC76_RS17765	COG0798	PFAM Bile acid sodium symporter
FORC76_RS17770	COG0640	Transcriptional regulator
FORC76_RS17775	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC76_RS17790	COG2207	Transcriptional regulator
FORC76_RS17795	COG4604	ABC transporter, ATP-binding protein
FORC76_RS17800	COG4605	iron ion homeostasis
FORC76_RS17805	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC76_RS17830	COG5380	lipid catabolic process
FORC76_RS17835	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FORC76_RS17840	COG0840	transmembrane signaling receptor activity
FORC76_RS17850	COG3240	lipase activity
FORC76_RS17860	COG2814	Major facilitator Superfamily
FORC76_RS17865	COG1757	Na H antiporter
FORC76_RS17880	COG0784	Response regulator, receiver
FORC76_RS17880	COG3437	response regulator, receiver
FORC76_RS17890	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FORC76_RS17895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FORC76_RS17900	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC76_RS17905	COG0513	Belongs to the DEAD box helicase family
FORC76_RS17920	COG2382	esterase
FORC76_RS17920	COG3507	Belongs to the glycosyl hydrolase 43 family
FORC76_RS17920	COG3693	PFAM glycoside hydrolase, family 10
FORC76_RS17940	COG3842	ATPase activity
FORC76_RS17960	COG1609	Transcriptional regulator
FORC76_RS17960	COG2207	Transcriptional regulator
FORC76_RS17965	COG3842	ATPase activity
FORC76_RS17975	COG2017	converts alpha-aldose to the beta-anomer
FORC76_RS17985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC76_RS17990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC76_RS18000	COG1070	Carbohydrate kinase
FORC76_RS18005	COG1609	Transcriptional regulator
FORC76_RS18005	COG2207	Transcriptional regulator
FORC76_RS18010	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC76_RS18015	COG2211	Major facilitator Superfamily
FORC76_RS18020	COG2115	Belongs to the xylose isomerase family
FORC76_RS18040	COG1484	DNA-dependent DNA replication
FORC76_RS18075	COG5433	transposase activity
FORC76_RS18080	COG1061	Type III restriction enzyme res subunit
FORC76_RS18120	COG0516	GMP reductase activity
FORC76_RS18135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC76_RS18145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC76_RS18175	COG3036	rescue of stalled ribosome
FORC76_RS18180	COG1278	Cold shock
FORC76_RS18185	COG1017	nitric oxide dioxygenase activity
FORC76_RS18185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC76_RS18190	COG3604	Transcriptional regulator
FORC76_RS18200	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC76_RS18205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC76_RS18220	COG0840	transmembrane signaling receptor activity
FORC76_RS18225	COG0714	Associated with various cellular activities
FORC76_RS18245	COG2304	oxidoreductase activity
FORC76_RS18260	COG1278	Cold shock
FORC76_RS18265	COG5001	Diguanylate cyclase
FORC76_RS18265	COG5002	protein histidine kinase activity
FORC76_RS18275	COG3530	Putative quorum-sensing-regulated virulence factor
FORC76_RS18290	COG0814	amino acid
FORC76_RS18295	COG0589	response to stress
FORC76_RS18305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC76_RS18305	COG2111	Na H antiporter
FORC76_RS18310	COG1006	Multisubunit Na H antiporter MnhC subunit
FORC76_RS18315	COG0651	ATP synthesis coupled electron transport
FORC76_RS18320	COG1863	multisubunit Na H antiporter MnhE subunit
FORC76_RS18325	COG2212	antiporter activity
FORC76_RS18330	COG1320	monovalent cation:proton antiporter activity
FORC76_RS18335	COG0242	peptide deformylase activity
FORC76_RS18385	COG2271	Major facilitator Superfamily
FORC76_RS18390	COG0584	glycerophosphoryl diester phosphodiesterase
FORC76_RS18405	COG1609	Transcriptional regulator
FORC76_RS18410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC76_RS18415	COG1879	ABC-type sugar transport system periplasmic component
FORC76_RS18420	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC76_RS18425	COG1129	ABC transporter
FORC76_RS18430	COG1869	D-ribose catabolic process
FORC76_RS18460	COG3501	Rhs element vgr protein
FORC76_RS18460	COG3409	Peptidoglycan-binding domain 1 protein
FORC76_RS18475	COG3409	Peptidoglycan-binding domain 1 protein
FORC76_RS18475	COG3501	Rhs element vgr protein
FORC76_RS18505	COG3829	transcription factor binding
FORC76_RS18570	COG0564	pseudouridine synthase activity
FORC76_RS18580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC76_RS18585	COG2771	luxR family
FORC76_RS18585	COG2200	EAL domain
FORC76_RS18595	COG0673	inositol 2-dehydrogenase activity
FORC76_RS18600	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC76_RS18635	COG1342	Belongs to the UPF0251 family
FORC76_RS18645	COG1301	dicarboxylic acid transport
FORC76_RS18650	COG0700	Nucleoside recognition
FORC76_RS18655	COG3366	ferrous iron transmembrane transporter activity
FORC76_RS18660	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC76_RS18670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC76_RS18675	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC76_RS18680	COG2259	Doxx family
FORC76_RS18705	COG0363	glucosamine-6-phosphate deaminase activity
FORC76_RS18715	COG0583	DNA-binding transcription factor activity
FORC76_RS18720	COG0366	Alpha amylase catalytic
FORC76_RS18725	COG1523	belongs to the glycosyl hydrolase 13 family
FORC76_RS18740	COG4580	involved in the transport of maltose and maltodextrins
FORC76_RS18755	COG0840	transmembrane signaling receptor activity
FORC76_RS18765	COG0840	transmembrane signaling receptor activity
FORC76_RS18770	COG3706	GGDEF domain
FORC76_RS18780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC76_RS18785	COG1126	abc transporter atp-binding protein
FORC76_RS18795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC76_RS18800	COG4597	amino acid ABC transporter
FORC76_RS18805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC76_RS18810	COG2213	PTS system mannitol-specific
FORC76_RS18810	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC76_RS18815	COG0246	Mannitol dehydrogenase
FORC76_RS18820	COG3722	fumarate hydratase activity
FORC76_RS18855	COG2910	NAD(P)H-binding
FORC76_RS18870	COG4221	oxidoreductase activity
FORC76_RS18880	COG1901	pseudouridine methyltransferase
FORC76_RS18895	COG0531	amino acid
FORC76_RS18900	COG1982	Orn Lys Arg decarboxylase major
FORC76_RS18910	COG2197	response regulator
FORC76_RS18960	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC76_RS18985	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FORC76_RS18995	COG0259	pyridoxamine-phosphate oxidase activity
FORC76_RS19025	COG0745	RESPONSE REGULATOR receiver
FORC76_RS19050	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC76_RS19055	COG0840	transmembrane signaling receptor activity
FORC76_RS19060	COG0835	chemotaxis
FORC76_RS19065	COG0835	chemotaxis
FORC76_RS19070	COG2198	Histidine kinase
FORC76_RS19070	COG0643	Histidine kinase
FORC76_RS19090	COG0601	transmembrane transport
FORC76_RS19095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC76_RS19100	COG4172	Belongs to the ABC transporter superfamily
FORC76_RS19105	COG1444	tRNA N-acetyltransferase activity
FORC76_RS19110	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine