locus-tag	class	description
AN947_RS00030	COG0217	transcriptional regulatory protein
AN947_RS00035	COG2084	Dehydrogenase
AN947_RS00055	COG2909	trisaccharide binding
AN947_RS00060	COG0058	SHG alpha-glucan phosphorylase activity
AN947_RS00065	COG1640	4-alpha-glucanotransferase
AN947_RS00070	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AN947_RS00085	COG3501	Rhs element vgr protein
AN947_RS00090	COG4104	PAAR repeat-containing protein
AN947_RS00120	COG0471	metal ion transport
AN947_RS00125	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AN947_RS00170	COG0671	phosphoesterase, PA-phosphatase related
AN947_RS00175	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AN947_RS00185	COG1999	signal sequence binding
AN947_RS00200	COG0786	glutamate:sodium symporter activity
AN947_RS00225	COG1566	PFAM secretion protein HlyD family protein
AN947_RS00260	COG3272	Protein of unknown function (DUF1722)
AN947_RS00270	COG0415	Belongs to the DNA photolyase family
AN947_RS00275	COG1388	LysM domain
AN947_RS00275	COG1376	ErfK ybiS ycfS ynhG family protein
AN947_RS00285	COG0513	Belongs to the DEAD box helicase family
AN947_RS00320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AN947_RS00325	COG0573	inorganic phosphate transmembrane transporter activity
AN947_RS00330	COG0581	inorganic phosphate transmembrane transporter activity
AN947_RS00335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AN947_RS00355	COG3314	Sporulation integral membrane protein YlbJ
AN947_RS00360	COG0659	secondary active sulfate transmembrane transporter activity
AN947_RS00370	COG0739	heme binding
AN947_RS00375	COG5001	Diguanylate cyclase
AN947_RS00375	COG3300	MHYT domain
AN947_RS00380	COG0583	DNA-binding transcription factor activity
AN947_RS00385	COG2814	Major facilitator Superfamily
AN947_RS00420	COG1342	Belongs to the UPF0251 family
AN947_RS00455	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AN947_RS00460	COG0673	inositol 2-dehydrogenase activity
AN947_RS00470	COG2200	EAL domain
AN947_RS00470	COG2771	luxR family
AN947_RS00475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN947_RS00485	COG0564	pseudouridine synthase activity
AN947_RS00550	COG3829	transcription factor binding
AN947_RS00585	COG3501	Rhs element vgr protein
AN947_RS00585	COG3409	Peptidoglycan-binding domain 1 protein
AN947_RS00600	COG1869	D-ribose catabolic process
AN947_RS00605	COG1129	ABC transporter
AN947_RS00610	COG1172	Belongs to the binding-protein-dependent transport system permease family
AN947_RS00615	COG1879	ABC-type sugar transport system periplasmic component
AN947_RS00620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN947_RS00625	COG1609	Transcriptional regulator
AN947_RS00635	COG3201	nicotinamide mononucleotide transporter
AN947_RS00640	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AN947_RS00650	COG0584	glycerophosphoryl diester phosphodiesterase
AN947_RS00655	COG2271	Major facilitator Superfamily
AN947_RS00695	COG0579	oxidoreductase
AN947_RS00705	COG0242	peptide deformylase activity
AN947_RS00715	COG1320	monovalent cation:proton antiporter activity
AN947_RS00720	COG2212	antiporter activity
AN947_RS00725	COG1863	multisubunit Na H antiporter MnhE subunit
AN947_RS00730	COG0651	ATP synthesis coupled electron transport
AN947_RS00735	COG1006	Multisubunit Na H antiporter MnhC subunit
AN947_RS00740	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AN947_RS00740	COG2111	Na H antiporter
AN947_RS00755	COG0814	amino acid
AN947_RS00775	COG3530	Putative quorum-sensing-regulated virulence factor
AN947_RS00785	COG5002	protein histidine kinase activity
AN947_RS00785	COG5001	Diguanylate cyclase
AN947_RS00790	COG1278	Cold shock
AN947_RS00805	COG2304	oxidoreductase activity
AN947_RS00825	COG0714	Associated with various cellular activities
AN947_RS00830	COG0840	transmembrane signaling receptor activity
AN947_RS00845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AN947_RS00850	COG2195	Cleaves the N-terminal amino acid of tripeptides
AN947_RS00860	COG3604	Transcriptional regulator
AN947_RS00865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN947_RS00865	COG1017	nitric oxide dioxygenase activity
AN947_RS00870	COG1278	Cold shock
AN947_RS00875	COG3036	rescue of stalled ribosome
AN947_RS00900	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AN947_RS00900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AN947_RS00905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AN947_RS00915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AN947_RS00930	COG0516	GMP reductase activity
AN947_RS00970	COG0513	Belongs to the DEAD box helicase family
AN947_RS00975	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AN947_RS00980	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AN947_RS00985	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AN947_RS00995	COG3437	response regulator, receiver
AN947_RS00995	COG0784	Response regulator, receiver
AN947_RS01000	COG4191	Histidine kinase
AN947_RS01000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN947_RS01010	COG1757	Na H antiporter
AN947_RS01015	COG2814	Major facilitator Superfamily
AN947_RS01025	COG3706	GGDEF domain
AN947_RS01030	COG3240	lipase activity
AN947_RS01040	COG0840	transmembrane signaling receptor activity
AN947_RS01045	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AN947_RS01050	COG5380	lipid catabolic process
AN947_RS01075	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN947_RS01080	COG4605	iron ion homeostasis
AN947_RS01085	COG4604	ABC transporter, ATP-binding protein
AN947_RS01090	COG2207	Transcriptional regulator
AN947_RS01105	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AN947_RS01125	COG0745	RESPONSE REGULATOR receiver
AN947_RS01135	COG3623	hexulose-6-phosphate isomerase
AN947_RS01140	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AN947_RS01145	COG0561	phosphatase activity
AN947_RS01175	COG3038	cytochrome b561
AN947_RS01180	COG0366	Alpha amylase catalytic
AN947_RS01205	COG0745	RESPONSE REGULATOR receiver
AN947_RS01210	COG5002	protein histidine kinase activity
AN947_RS01235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AN947_RS01250	COG2814	Major facilitator Superfamily
AN947_RS01265	COG1686	Belongs to the peptidase S11 family
AN947_RS01295	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AN947_RS01295	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AN947_RS01300	COG0509	glycine decarboxylation via glycine cleavage system
AN947_RS01305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AN947_RS01315	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AN947_RS01325	COG3039	Transposase
AN947_RS01360	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AN947_RS01365	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AN947_RS01435	COG1028	Short-chain dehydrogenase reductase Sdr
AN947_RS01500	COG0494	nUDIX hydrolase
AN947_RS01520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN947_RS01525	COG3040	lipid binding
AN947_RS01570	COG3041	Addiction module toxin RelE StbE family
AN947_RS01685	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AN947_RS01695	COG1280	lysine exporter protein (LysE YggA)
AN947_RS01905	COG3549	Plasmid maintenance system killer
AN947_RS01910	COG3093	addiction module antidote protein HigA
AN947_RS01930	COG1619	proteins homologs of microcin C7 resistance protein MccF
AN947_RS01955	COG3040	lipid binding
AN947_RS02020	COG4977	sequence-specific DNA binding
AN947_RS02125	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AN947_RS02130	COG2944	sequence-specific DNA binding
AN947_RS02150	COG3039	Transposase
AN947_RS02155	COG0110	maltose O-acetyltransferase activity
AN947_RS02175	COG0346	lactoylglutathione lyase activity
AN947_RS02355	COG0346	lactoylglutathione lyase activity
AN947_RS02375	COG1328	CTP reductase activity
AN947_RS02380	COG0602	queuosine metabolic process
AN947_RS02395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN947_RS02395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN947_RS02395	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AN947_RS02400	COG1105	Belongs to the carbohydrate kinase PfkB family
AN947_RS02405	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN947_RS02405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN947_RS02410	COG1609	Transcriptional regulator
AN947_RS02415	COG0420	3'-5' exonuclease activity
AN947_RS02420	COG0419	ATPase involved in DNA repair
AN947_RS02425	COG2205	protein histidine kinase activity
AN947_RS02425	COG0784	Response regulator, receiver
AN947_RS02430	COG0156	8-amino-7-oxononanoate synthase activity
AN947_RS02445	COG0523	cobalamin synthesis protein
AN947_RS02460	COG0674	pyruvate-flavodoxin oxidoreductase activity
AN947_RS02460	COG1013	pyruvate-flavodoxin oxidoreductase activity
AN947_RS02460	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AN947_RS02460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AN947_RS02470	COG0745	RESPONSE REGULATOR receiver
AN947_RS02475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AN947_RS02480	COG0586	Pfam SNARE associated Golgi protein
AN947_RS02490	COG2200	EAL domain
AN947_RS02500	COG3038	cytochrome b561
AN947_RS02510	COG2116	formate transmembrane transporter activity
AN947_RS02515	COG0583	DNA-binding transcription factor activity
AN947_RS02530	COG0737	Belongs to the 5'-nucleotidase family
AN947_RS02545	COG2824	Alkylphosphonate utilization operon protein PhnA
AN947_RS02580	COG2199	diguanylate cyclase activity
AN947_RS02600	COG3706	GGDEF domain
AN947_RS02615	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AN947_RS02620	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AN947_RS02630	COG0745	RESPONSE REGULATOR receiver
AN947_RS02645	COG3140	Belongs to the UPF0181 family
AN947_RS02650	COG4128	Pfam Zonular occludens toxin
AN947_RS02695	COG0023	Translation Initiation Factor
AN947_RS02715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN947_RS02715	COG0045	succinate-CoA ligase (ADP-forming) activity
AN947_RS02715	COG1042	CoA-binding domain protein
AN947_RS02720	COG0583	DNA-binding transcription factor activity
AN947_RS02725	COG1629	transport
AN947_RS02725	COG4771	TonB-dependent receptor
AN947_RS02745	COG2050	protein possibly involved in aromatic compounds catabolism
AN947_RS02770	COG0625	glutathione transferase activity
AN947_RS02785	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AN947_RS02790	COG4172	Belongs to the ABC transporter superfamily
AN947_RS02795	COG4239	(ABC) transporter, permease
AN947_RS02800	COG4174	ABC transporter (Permease)
AN947_RS02805	COG4166	transmembrane transport
AN947_RS02830	COG3104	oligopeptide transport
AN947_RS02850	COG3842	ATPase activity
AN947_RS02860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AN947_RS02865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AN947_RS02870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN947_RS02875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AN947_RS02880	COG1011	Hydrolase
AN947_RS02890	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AN947_RS02895	COG1970	mechanosensitive ion channel activity
AN947_RS02900	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AN947_RS02905	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AN947_RS02905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AN947_RS02910	COG0302	gtp cyclohydrolase
AN947_RS02920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AN947_RS02930	COG2897	thiosulfate sulfurtransferase activity
AN947_RS02935	COG2390	Transcriptional regulator
AN947_RS02950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AN947_RS02975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AN947_RS03000	COG0583	DNA-binding transcription factor activity
AN947_RS03005	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AN947_RS03050	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN947_RS03095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN947_RS03095	COG1263	PTS System
AN947_RS03100	COG1609	Transcriptional regulator
AN947_RS03110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN947_RS03115	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AN947_RS03125	COG2885	chlorophyll binding
AN947_RS03130	COG0545	Peptidyl-prolyl cis-trans isomerase
AN947_RS03135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN947_RS03140	COG0840	transmembrane signaling receptor activity
AN947_RS03150	COG3069	C4-dicarboxylate transmembrane transporter activity
AN947_RS03155	COG1760	l-serine dehydratase
AN947_RS03175	COG1609	Transcriptional regulator
AN947_RS03180	COG2197	response regulator
AN947_RS03185	COG3850	Histidine kinase
AN947_RS03190	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AN947_RS03200	COG0243	molybdopterin cofactor binding
AN947_RS03220	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AN947_RS03225	COG2197	response regulator
AN947_RS03230	COG3851	Histidine kinase
AN947_RS03235	COG2271	Major facilitator Superfamily
AN947_RS03240	COG1840	ABC-type Fe3 transport system, periplasmic component
AN947_RS03250	COG3842	ATPase activity
AN947_RS03255	COG3243	poly(R)-hydroxyalkanoic acid synthase
AN947_RS03265	COG0183	Belongs to the thiolase family
AN947_RS03275	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AN947_RS03280	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AN947_RS03295	COG2131	deaminase
AN947_RS03320	COG3621	Patatin-like phospholipase
AN947_RS03365	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AN947_RS03375	COG1979	alcohol dehydrogenase
AN947_RS03390	COG4191	Histidine kinase
AN947_RS03400	COG2271	Major facilitator Superfamily
AN947_RS03405	COG0469	pyruvate kinase activity
AN947_RS03410	COG0784	Response regulator, receiver
AN947_RS03410	COG2198	Histidine kinase
AN947_RS03410	COG2205	protein histidine kinase activity
AN947_RS03415	COG1879	ABC-type sugar transport system periplasmic component
AN947_RS03420	COG1803	Methylglyoxal synthase
AN947_RS03425	COG1335	isochorismatase
AN947_RS03430	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AN947_RS03445	COG0210	DNA helicase
AN947_RS03450	COG1289	transmembrane transporter activity
AN947_RS03480	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AN947_RS03485	COG4149	molybdate abc transporter
AN947_RS03490	COG0725	ABC transporter, periplasmic molybdate-binding protein
AN947_RS03495	COG1492	cobalamin metabolic process
AN947_RS03540	COG5002	protein histidine kinase activity
AN947_RS03540	COG0784	Response regulator, receiver
AN947_RS03545	COG1879	ABC-type sugar transport system periplasmic component
AN947_RS03555	COG2827	Endonuclease containing a URI domain
AN947_RS03570	COG2926	Belongs to the UPF0265 family
AN947_RS03585	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AN947_RS03590	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AN947_RS03595	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AN947_RS03600	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AN947_RS03605	COG0247	lactate metabolic process
AN947_RS03610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AN947_RS03615	COG3118	belongs to the thioredoxin family
AN947_RS03645	COG0583	DNA-binding transcription factor activity
AN947_RS03650	COG4160	amino acid transport
AN947_RS03655	COG4215	(ABC) transporter
AN947_RS03660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN947_RS03665	COG1126	abc transporter atp-binding protein
AN947_RS03675	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AN947_RS03685	COG0494	nUDIX hydrolase
AN947_RS03690	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AN947_RS03700	COG1309	transcriptional regulator
AN947_RS03705	COG0513	Belongs to the DEAD box helicase family
AN947_RS03710	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AN947_RS03720	COG0814	amino acid
AN947_RS03725	COG0840	transmembrane signaling receptor activity
AN947_RS03730	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AN947_RS03740	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AN947_RS03750	COG1984	allophanate hydrolase subunit 2
AN947_RS03765	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AN947_RS03770	COG4181	ATPase activity
AN947_RS03780	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AN947_RS03785	COG1716	ATPase activity
AN947_RS03785	COG5001	Diguanylate cyclase
AN947_RS03800	COG0484	heat shock protein binding
AN947_RS03840	COG0546	phosphoglycolate phosphatase activity
AN947_RS03855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN947_RS03860	COG1368	sulfuric ester hydrolase activity
AN947_RS03870	COG0513	Belongs to the DEAD box helicase family
AN947_RS03885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AN947_RS03895	COG3046	protein related to deoxyribodipyrimidine photolyase
AN947_RS03900	COG3397	chitin binding
AN947_RS03905	COG3227	Zinc metalloprotease (Elastase)
AN947_RS03915	COG0010	Belongs to the arginase family
AN947_RS03920	COG1166	arginine decarboxylase activity
AN947_RS03935	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AN947_RS03950	COG0527	aspartate kinase activity
AN947_RS03955	COG0662	Cupin 2, conserved barrel domain protein
AN947_RS03965	COG0456	acetyltransferase
AN947_RS03975	COG3186	Phenylalanine-4-hydroxylase
AN947_RS04000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AN947_RS04025	COG1253	flavin adenine dinucleotide binding
AN947_RS04030	COG1765	OsmC-like protein
AN947_RS04055	COG0531	amino acid
AN947_RS04070	COG3279	Response regulator of the LytR AlgR family
AN947_RS04075	COG3275	phosphorelay sensor kinase activity
AN947_RS04090	COG1136	(ABC) transporter
AN947_RS04090	COG0577	efflux transmembrane transporter activity
AN947_RS04095	COG1136	(ABC) transporter
AN947_RS04110	COG4989	oxidoreductase activity
AN947_RS04115	COG0366	Alpha amylase catalytic
AN947_RS04125	COG2067	long-chain fatty acid transport protein
AN947_RS04130	COG2267	carboxylic ester hydrolase activity
AN947_RS04140	COG3227	Zinc metalloprotease (Elastase)
AN947_RS04150	COG3047	cAMP biosynthetic process
AN947_RS04160	COG1686	Belongs to the peptidase S11 family
AN947_RS04165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN947_RS04170	COG1271	oxidase subunit
AN947_RS04175	COG1294	oxidase, subunit
AN947_RS04195	COG3048	D-serine ammonia-lyase activity
AN947_RS04200	COG0583	DNA-binding transcription factor activity
AN947_RS04250	COG1063	alcohol dehydrogenase
AN947_RS04280	COG0346	lactoylglutathione lyase activity
AN947_RS04300	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AN947_RS04305	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AN947_RS04310	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AN947_RS04315	COG0363	glucosamine-6-phosphate deaminase activity
AN947_RS04320	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AN947_RS04345	COG1929	Belongs to the glycerate kinase type-1 family
AN947_RS04350	COG2610	gluconate transmembrane transporter activity
AN947_RS04355	COG3835	regulator
AN947_RS04365	COG0748	coenzyme F420 binding
AN947_RS04370	COG3721	Heme iron utilization protein
AN947_RS04380	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AN947_RS04385	COG0811	peptide transport
AN947_RS04390	COG0848	biopolymer transport protein
AN947_RS04395	COG4558	Periplasmic binding protein
AN947_RS04405	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AN947_RS04440	COG3217	Mosc domain protein beta barrel domain protein
AN947_RS04440	COG3217	Mosc domain protein beta barrel domain protein
AN947_RS04440	COG0633	Ferredoxin
AN947_RS04440	COG0633	Ferredoxin
AN947_RS04445	COG0418	dihydroorotase activity
AN947_RS04455	COG3152	Membrane
AN947_RS04465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AN947_RS04470	COG2354	Protein conserved in bacteria
AN947_RS04475	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AN947_RS04480	COG1278	Cold shock
AN947_RS04510	COG2199	diguanylate cyclase activity
AN947_RS04515	COG1349	DNA-binding transcription factor activity
AN947_RS04530	COG3833	ABC-type maltose transport systems, permease component
AN947_RS04535	COG1175	transmembrane transport
AN947_RS04545	COG3842	ATPase activity
AN947_RS04550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN947_RS04565	COG0393	Putative heavy-metal-binding
AN947_RS04575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AN947_RS04580	COG0784	Response regulator, receiver
AN947_RS04580	COG0835	chemotaxis
AN947_RS04585	COG1846	Transcriptional regulator
AN947_RS04590	COG3706	GGDEF domain
AN947_RS04630	COG0583	DNA-binding transcription factor activity
AN947_RS04635	COG5001	Diguanylate cyclase
AN947_RS04645	COG1741	Belongs to the pirin family
AN947_RS04650	COG3123	guanosine phosphorylase activity
AN947_RS04660	COG2211	Major facilitator Superfamily
AN947_RS04670	COG0840	transmembrane signaling receptor activity
AN947_RS04675	COG1067	ATP-dependent peptidase activity
AN947_RS04685	COG4172	Belongs to the ABC transporter superfamily
AN947_RS04710	COG0583	DNA-binding transcription factor activity
AN947_RS04715	COG1620	l-lactate permease
AN947_RS04730	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AN947_RS04740	COG0840	transmembrane signaling receptor activity
AN947_RS04750	COG0513	Belongs to the DEAD box helicase family
AN947_RS04755	COG0583	DNA-binding transcription factor activity
AN947_RS04765	COG1902	pentaerythritol trinitrate reductase activity
AN947_RS04775	COG1132	(ABC) transporter
AN947_RS04785	COG1902	pentaerythritol trinitrate reductase activity
AN947_RS04795	COG1280	lysine exporter protein (LysE YggA)
AN947_RS04800	COG2207	Transcriptional regulator
AN947_RS04820	COG1846	Transcriptional regulator
AN947_RS04825	COG1764	response to oxidative stress
AN947_RS04830	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AN947_RS04835	COG0697	spore germination
AN947_RS04845	COG0700	Nucleoside recognition
AN947_RS04850	COG3366	ferrous iron transmembrane transporter activity
AN947_RS04865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AN947_RS04870	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AN947_RS04875	COG2259	Doxx family
AN947_RS04900	COG0363	glucosamine-6-phosphate deaminase activity
AN947_RS04915	COG4580	involved in the transport of maltose and maltodextrins
AN947_RS04930	COG0840	transmembrane signaling receptor activity
AN947_RS04945	COG0840	transmembrane signaling receptor activity
AN947_RS04955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AN947_RS04960	COG1126	abc transporter atp-binding protein
AN947_RS04970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN947_RS04975	COG4597	amino acid ABC transporter
AN947_RS04980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AN947_RS04990	COG0739	heme binding
AN947_RS05005	COG0246	Mannitol dehydrogenase
AN947_RS05010	COG3722	fumarate hydratase activity
AN947_RS05015	COG0673	inositol 2-dehydrogenase activity
AN947_RS05045	COG2910	NAD(P)H-binding
AN947_RS05055	COG0840	transmembrane signaling receptor activity
AN947_RS05060	COG4221	oxidoreductase activity
AN947_RS05070	COG1901	pseudouridine methyltransferase
AN947_RS05085	COG0531	amino acid
AN947_RS05090	COG1982	Orn Lys Arg decarboxylase major
AN947_RS05125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN947_RS05150	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AN947_RS05190	COG0745	RESPONSE REGULATOR receiver
AN947_RS05215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AN947_RS05220	COG0840	transmembrane signaling receptor activity
AN947_RS05225	COG0835	chemotaxis
AN947_RS05230	COG0835	chemotaxis
AN947_RS05235	COG2198	Histidine kinase
AN947_RS05235	COG0643	Histidine kinase
AN947_RS05255	COG0601	transmembrane transport
AN947_RS05260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN947_RS05270	COG2194	sulfuric ester hydrolase activity
AN947_RS05275	COG0642	Histidine kinase
AN947_RS05310	COG1444	tRNA N-acetyltransferase activity
AN947_RS05315	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AN947_RS05335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AN947_RS05340	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AN947_RS05355	COG0594	ribonuclease P activity
AN947_RS05360	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AN947_RS05365	COG1126	abc transporter atp-binding protein
AN947_RS05380	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AN947_RS05385	COG0592	DNA-directed DNA polymerase activity
AN947_RS05390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AN947_RS05395	COG0187	DNA topoisomerase II activity
AN947_RS05410	COG0071	Belongs to the small heat shock protein (HSP20) family
AN947_RS05415	COG3977	Valine--pyruvate aminotransferase
AN947_RS05425	COG0751	glycine-tRNA ligase activity
AN947_RS05430	COG0752	glycyl-tRNA synthetase alpha subunit
AN947_RS05435	COG2119	membrane
AN947_RS05445	COG0425	Belongs to the sulfur carrier protein TusA family
AN947_RS05455	COG0604	alcohol dehydrogenase
AN947_RS05465	COG0129	dihydroxy-acid dehydratase activity
AN947_RS05470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN947_RS05485	COG0606	chelatase, subunit chli
AN947_RS05490	COG0204	Acyl-transferase
AN947_RS05495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN947_RS05515	COG3084	Protein conserved in bacteria
AN947_RS05525	COG4326	sporulation control protein
AN947_RS05530	COG1272	protein, Hemolysin III
AN947_RS05540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AN947_RS05545	COG0569	domain protein
AN947_RS05550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AN947_RS05550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AN947_RS05555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AN947_RS05560	COG0242	peptide deformylase activity
AN947_RS05565	COG1652	LysM domain
AN947_RS05570	COG0758	DNA mediated transformation
AN947_RS05575	COG2922	Belongs to the Smg family
AN947_RS05580	COG0551	DNA topoisomerase type I activity
AN947_RS05585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AN947_RS05590	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AN947_RS05595	COG0009	L-threonylcarbamoyladenylate synthase
AN947_RS05600	COG0408	coproporphyrinogen oxidase activity
AN947_RS05605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AN947_RS05615	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AN947_RS05655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AN947_RS05660	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AN947_RS05670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AN947_RS05675	COG2104	thiamine diphosphate biosynthetic process
AN947_RS05680	COG2022	thiamine diphosphate biosynthetic process
AN947_RS05685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AN947_RS05690	COG0006	proline dipeptidase activity
AN947_RS05690	COG0006	proline dipeptidase activity
AN947_RS05710	COG1522	sequence-specific DNA binding
AN947_RS05715	COG5001	Diguanylate cyclase
AN947_RS05715	COG5002	protein histidine kinase activity
AN947_RS05735	COG0589	response to stress
AN947_RS05745	COG1528	Iron-storage protein
AN947_RS05755	COG2081	HI0933 family
AN947_RS05765	COG1322	Protein conserved in bacteria
AN947_RS05770	COG2226	methyltransferase
AN947_RS05785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AN947_RS05790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AN947_RS05795	COG0805	protein transport
AN947_RS05800	COG1858	cytochrome C peroxidase
AN947_RS05805	COG0534	Mate efflux family protein
AN947_RS05815	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AN947_RS05830	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AN947_RS05835	COG3161	chorismate lyase activity
AN947_RS05845	COG1580	Controls the rotational direction of flagella during chemotaxis
AN947_RS05850	COG0840	transmembrane signaling receptor activity
AN947_RS05860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN947_RS05885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN947_RS05885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN947_RS05905	COG3078	GTPase activator activity
AN947_RS05920	COG3071	HemY protein
AN947_RS05925	COG2959	enzyme of heme biosynthesis
AN947_RS05930	COG1587	Uroporphyrinogen-III synthase
AN947_RS05935	COG0181	hydroxymethylbilane synthase activity
AN947_RS05950	COG1965	Belongs to the frataxin family
AN947_RS05960	COG0019	diaminopimelate decarboxylase activity
AN947_RS05965	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AN947_RS05975	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AN947_RS05980	COG1011	Hydrolase
AN947_RS05985	COG2200	EAL domain
AN947_RS05985	COG2199	diguanylate cyclase activity
AN947_RS05985	COG3287	FIST C domain
AN947_RS06005	COG0561	phosphatase activity
AN947_RS06010	COG2267	carboxylic ester hydrolase activity
AN947_RS06015	COG1280	lysine exporter protein (LysE YggA)
AN947_RS06020	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AN947_RS06025	COG0783	Belongs to the Dps family
AN947_RS06065	COG0742	ribosomal rna small subunit methyltransferase
AN947_RS06075	COG2884	Cell division ATP-binding protein ftsE
AN947_RS06080	COG2177	Part of the ABC transporter FtsEX involved in
AN947_RS06085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AN947_RS06110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AN947_RS06120	COG1404	Belongs to the peptidase S8 family
AN947_RS06125	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AN947_RS06160	COG0583	DNA-binding transcription factor activity
AN947_RS06165	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AN947_RS06170	COG2960	long-chain fatty acid transporting porin activity
AN947_RS06175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AN947_RS06180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN947_RS06185	COG1309	transcriptional regulator
AN947_RS06240	COG0747	negative chemotaxis
AN947_RS06245	COG0601	transmembrane transport
AN947_RS06250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN947_RS06260	COG2131	deaminase
AN947_RS06285	COG3621	Patatin-like phospholipase
AN947_RS06330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN947_RS06335	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AN947_RS06345	COG0210	DNA helicase
AN947_RS06355	COG1280	lysine exporter protein (LysE YggA)
AN947_RS06370	COG2962	Rard protein
AN947_RS06375	COG0514	ATP-dependent DNA helicase (RecQ)
AN947_RS06390	COG1132	(ABC) transporter
AN947_RS06395	COG4774	siderophore transport
AN947_RS06400	COG1120	ATPase activity
AN947_RS06425	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AN947_RS06430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN947_RS06430	COG1263	PTS System
AN947_RS06435	COG2862	Uncharacterized protein family, UPF0114
AN947_RS06440	COG1561	YicC-like family, N-terminal region
AN947_RS06445	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AN947_RS06450	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AN947_RS06455	COG1560	Kdo2-lipid A biosynthetic process
AN947_RS06460	COG1560	Kdo2-lipid A biosynthetic process
AN947_RS06465	COG1309	transcriptional regulator
AN947_RS06475	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AN947_RS06490	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AN947_RS06495	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AN947_RS06505	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AN947_RS06510	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AN947_RS06515	COG0859	PFAM glycosyl transferase family 9
AN947_RS06520	COG0463	Glycosyl transferase, family 2
AN947_RS06525	COG0859	PFAM glycosyl transferase family 9
AN947_RS06530	COG3642	lipopolysaccharide core region biosynthetic process
AN947_RS06560	COG1519	Transferase
AN947_RS06595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN947_RS06605	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AN947_RS06640	COG5433	transposase activity
AN947_RS06660	COG1051	belongs to the nudix hydrolase family
AN947_RS06685	COG1215	transferase activity, transferring glycosyl groups
AN947_RS06690	COG1216	Glycosyl transferase, family 2
AN947_RS06700	COG0367	asparagine synthase
AN947_RS06705	COG0438	transferase activity, transferring glycosyl groups
AN947_RS06710	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AN947_RS06710	COG0662	Cupin 2, conserved barrel domain protein
AN947_RS06725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AN947_RS06745	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AN947_RS06760	COG0668	transmembrane transport
AN947_RS06770	COG3068	Protein conserved in bacteria
AN947_RS06775	COG1253	flavin adenine dinucleotide binding
AN947_RS06780	COG0776	regulation of translation
AN947_RS06790	COG0151	Belongs to the GarS family
AN947_RS06805	COG0789	Transcriptional regulator
AN947_RS06810	COG3710	Transcriptional regulator
AN947_RS06815	COG0531	amino acid
AN947_RS06820	COG1982	Orn Lys Arg decarboxylase major
AN947_RS06825	COG0840	transmembrane signaling receptor activity
AN947_RS06840	COG0800	Aldolase
AN947_RS06855	COG0129	dihydroxy-acid dehydratase activity
AN947_RS06860	COG1609	Transcriptional regulator
AN947_RS06865	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AN947_RS06870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AN947_RS06875	COG2264	protein methyltransferase activity
AN947_RS06880	COG0439	Biotin carboxylase
AN947_RS06885	COG0511	ligase activity, forming carbon-carbon bonds
AN947_RS06890	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AN947_RS06895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AN947_RS06915	COG2814	Major facilitator Superfamily
AN947_RS06920	COG2205	protein histidine kinase activity
AN947_RS06920	COG0784	Response regulator, receiver
AN947_RS06925	COG0248	Ppx GppA phosphatase
AN947_RS06930	COG0513	Belongs to the DEAD box helicase family
AN947_RS06935	COG3118	belongs to the thioredoxin family
AN947_RS06950	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AN947_RS06995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN947_RS07005	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AN947_RS07015	COG1072	(Pantothenic acid kinase))
AN947_RS07040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AN947_RS07045	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AN947_RS07050	COG0250	Participates in transcription elongation, termination and antitermination
AN947_RS07055	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AN947_RS07065	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AN947_RS07070	COG0222	ribosome binding
AN947_RS07075	COG0085	RNA polymerase activity
AN947_RS07080	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AN947_RS07085	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AN947_RS07090	COG2816	NAD+ diphosphatase activity
AN947_RS07095	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AN947_RS07110	COG4942	peptidase
AN947_RS07115	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AN947_RS07125	COG0471	metal ion transport
AN947_RS07125	COG0490	domain, Protein
AN947_RS07130	COG0688	phosphatidylethanolamine metabolic process
AN947_RS07140	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AN947_RS07185	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AN947_RS07190	COG0802	atpase or kinase
AN947_RS07200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AN947_RS07205	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AN947_RS07210	COG1923	regulation of RNA biosynthetic process
AN947_RS07215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AN947_RS07220	COG0330	HflC and HflK could
AN947_RS07225	COG0330	HflC and HflK could
AN947_RS07230	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AN947_RS07235	COG2900	Belongs to the SlyX family
AN947_RS07245	COG0545	Peptidyl-prolyl cis-trans isomerase
AN947_RS07250	COG2964	Protein conserved in bacteria
AN947_RS07255	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AN947_RS07260	COG2923	Belongs to the DsrF TusC family
AN947_RS07275	COG0049	tRNA binding
AN947_RS07280	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AN947_RS07285	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AN947_RS07290	COG2906	2 iron, 2 sulfur cluster binding
AN947_RS07300	COG0360	Binds together with S18 to 16S ribosomal RNA
AN947_RS07310	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AN947_RS07330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AN947_RS07335	COG0432	Pfam Uncharacterised protein family UPF0047
AN947_RS07355	COG0735	belongs to the Fur family
AN947_RS07360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AN947_RS07385	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AN947_RS07395	COG0175	sulfate reduction
AN947_RS07435	COG1410	methionine synthase
AN947_RS07435	COG0646	methionine synthase
AN947_RS07440	COG0527	aspartate kinase activity
AN947_RS07445	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AN947_RS07455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AN947_RS07470	COG0629	single-stranded DNA binding
AN947_RS07475	COG2199	diguanylate cyclase activity
AN947_RS07475	COG2200	EAL domain
AN947_RS07500	COG3267	Type II secretory pathway component ExeA
AN947_RS07500	COG3409	Peptidoglycan-binding domain 1 protein
AN947_RS07510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AN947_RS07515	COG1459	type II secretion system
AN947_RS07525	COG2165	general secretion pathway protein
AN947_RS07530	COG2165	general secretion pathway protein
AN947_RS07560	COG1077	Cell shape determining protein MreB Mrl
AN947_RS07565	COG1792	Involved in formation and maintenance of cell shape
AN947_RS07570	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AN947_RS07575	COG0424	maF-like protein
AN947_RS07585	COG3164	Protein of unknown function
AN947_RS07590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AN947_RS07595	COG0312	modulator of DNA gyrase
AN947_RS07600	COG2235	arginine
AN947_RS07620	COG0589	response to stress
AN947_RS07630	COG2358	TRAP transporter, solute receptor (TAXI family
AN947_RS07640	COG1438	arginine binding
AN947_RS07645	COG0039	L-malate dehydrogenase activity
AN947_RS07650	COG0531	amino acid
AN947_RS07655	COG0531	amino acid
AN947_RS07660	COG0142	geranyltranstransferase activity
AN947_RS07665	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AN947_RS07670	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AN947_RS07675	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AN947_RS07680	COG2966	Psort location CytoplasmicMembrane, score
AN947_RS07685	COG3610	response to peptide
AN947_RS07695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AN947_RS07700	COG2967	ApaG domain
AN947_RS07705	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AN947_RS07710	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AN947_RS07715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AN947_RS07720	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AN947_RS07725	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AN947_RS07780	COG0741	lytic transglycosylase activity
AN947_RS07785	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AN947_RS07805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AN947_RS07810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AN947_RS07820	COG1872	DUF167
AN947_RS07825	COG0762	integral membrane protein
AN947_RS07830	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AN947_RS07835	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AN947_RS07855	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AN947_RS07860	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AN947_RS07865	COG1678	Uncharacterized ACR, COG1678
AN947_RS07870	COG0189	ligase activity
AN947_RS07875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AN947_RS07880	COG2356	endonuclease I
AN947_RS07890	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AN947_RS07900	COG0583	DNA-binding transcription factor activity
AN947_RS07905	COG4771	TonB-dependent receptor
AN947_RS07910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AN947_RS07915	COG0126	phosphoglycerate kinase activity
AN947_RS07920	COG0191	fructose-bisphosphate aldolase activity
AN947_RS07930	COG0668	transmembrane transport
AN947_RS07935	COG1279	arginine transmembrane transporter activity
AN947_RS07960	COG1349	DNA-binding transcription factor activity
AN947_RS07965	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AN947_RS07970	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AN947_RS08020	COG0328	RNA-DNA hybrid ribonuclease activity
AN947_RS08035	COG4969	Belongs to the N-Me-Phe pilin family
AN947_RS08045	COG0739	heme binding
AN947_RS08080	COG2003	Belongs to the UPF0758 family
AN947_RS08090	COG0840	transmembrane signaling receptor activity
AN947_RS08100	COG2207	Transcriptional regulator
AN947_RS08110	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AN947_RS08115	COG0582	viral genome integration into host DNA
AN947_RS08130	COG0358	DNA primase activity
AN947_RS08135	COG1610	YqeY-like protein
AN947_RS08140	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AN947_RS08145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AN947_RS08155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AN947_RS08165	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AN947_RS08170	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AN947_RS08180	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AN947_RS08185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AN947_RS08190	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AN947_RS08195	COG0585	pseudouridine synthase activity
AN947_RS08200	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AN947_RS08205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AN947_RS08215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AN947_RS08220	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AN947_RS08240	COG4208	sulfate ABC transporter
AN947_RS08245	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AN947_RS08255	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AN947_RS08265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AN947_RS08270	COG0527	aspartate kinase activity
AN947_RS08275	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AN947_RS08320	COG3630	sodium ion export across plasma membrane
AN947_RS08325	COG0511	ligase activity, forming carbon-carbon bonds
AN947_RS08325	COG5016	pyruvate
AN947_RS08330	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AN947_RS08340	COG1238	metal cluster binding
AN947_RS08345	COG0612	Peptidase, M16
AN947_RS08350	COG2918	glutathione biosynthetic process
AN947_RS08355	COG1854	S-ribosylhomocysteine lyase activity
AN947_RS08360	COG4536	flavin adenine dinucleotide binding
AN947_RS08365	COG4137	Cytochrome C assembly protein
AN947_RS08370	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AN947_RS08375	COG0228	four-way junction DNA binding
AN947_RS08380	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AN947_RS08385	COG0336	Belongs to the RNA methyltransferase TrmD family
AN947_RS08390	COG0335	large ribosomal subunit rRNA binding
AN947_RS08395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN947_RS08400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN947_RS08410	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AN947_RS08415	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AN947_RS08420	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AN947_RS08425	COG0723	plastoquinol--plastocyanin reductase activity
AN947_RS08430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AN947_RS08435	COG2857	Cytochrome c1
AN947_RS08440	COG0625	glutathione transferase activity
AN947_RS08445	COG2969	positive regulation of protein catabolic process
AN947_RS08450	COG2823	Periplasmic or secreted lipoprotein
AN947_RS08455	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AN947_RS08460	COG0792	nuclease activity
AN947_RS08465	COG3107	peptidoglycan biosynthetic process
AN947_RS08470	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AN947_RS08495	COG0659	secondary active sulfate transmembrane transporter activity
AN947_RS08500	COG1131	(ABC) transporter
AN947_RS08505	COG0842	Transport permease protein
AN947_RS08510	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AN947_RS08515	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AN947_RS08520	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AN947_RS08530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AN947_RS08550	COG1643	Atp-dependent helicase
AN947_RS08560	COG1752	Esterase of the alpha-beta hydrolase superfamily
AN947_RS08570	COG3112	Uncharacterised protein family (UPF0231)
AN947_RS08575	COG0347	Belongs to the P(II) protein family
AN947_RS08580	COG0004	ammonium transporteR
AN947_RS08585	COG1840	ABC-type Fe3 transport system, periplasmic component
AN947_RS08595	COG3842	ATPase activity
AN947_RS08615	COG2971	BadF BadG BcrA BcrD
AN947_RS08625	COG4608	Belongs to the ABC transporter superfamily
AN947_RS08630	COG0444	Belongs to the ABC transporter superfamily
AN947_RS08635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN947_RS08640	COG0601	transmembrane transport
AN947_RS08645	COG0747	negative chemotaxis
AN947_RS08655	COG2205	protein histidine kinase activity
AN947_RS08655	COG0784	Response regulator, receiver
AN947_RS08660	COG2813	Specifically methylates the guanine in position
AN947_RS08665	COG0628	permease
AN947_RS08670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AN947_RS08675	COG0316	Belongs to the HesB IscA family
AN947_RS08690	COG0739	heme binding
AN947_RS08695	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AN947_RS08700	COG2027	D-alanyl-D-alanine carboxypeptidase
AN947_RS08705	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AN947_RS08710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AN947_RS08715	COG1534	Rna-binding protein
AN947_RS08720	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AN947_RS08725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AN947_RS08730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AN947_RS08745	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AN947_RS08760	COG0779	Required for maturation of 30S ribosomal subunits
AN947_RS08765	COG0195	Participates in both transcription termination and antitermination
AN947_RS08770	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AN947_RS08775	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AN947_RS08785	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AN947_RS08810	COG0826	peptidase U32
AN947_RS08815	COG0826	peptidase U32
AN947_RS08825	COG3154	lipid carrier protein
AN947_RS08830	COG3153	acetyltransferase
AN947_RS08850	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AN947_RS08905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AN947_RS08970	COG1196	nuclear chromosome segregation
AN947_RS09000	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
AN947_RS09045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN947_RS09060	COG0681	Belongs to the peptidase S26 family
AN947_RS09095	COG2356	endonuclease I
AN947_RS09110	COG0629	single-stranded DNA binding
AN947_RS09125	COG0714	Associated with various cellular activities
AN947_RS09150	COG2003	Belongs to the UPF0758 family
AN947_RS09175	COG2205	protein histidine kinase activity
AN947_RS09175	COG3437	response regulator, receiver
AN947_RS09175	COG3850	Histidine kinase
AN947_RS09175	COG4999	Histidine kinase
AN947_RS09240	COG0513	Belongs to the DEAD box helicase family
AN947_RS09260	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AN947_RS09265	COG2204	response regulator
AN947_RS09275	COG0667	Aldo Keto reductase
AN947_RS09285	COG0494	nUDIX hydrolase
AN947_RS09290	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AN947_RS09295	COG0730	response to heat
AN947_RS09300	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AN947_RS09310	COG1283	sodium-dependent phosphate transmembrane transporter activity
AN947_RS09315	COG0583	DNA-binding transcription factor activity
AN947_RS09320	COG0640	Transcriptional regulator
AN947_RS09325	COG0268	Binds directly to 16S ribosomal RNA
AN947_RS09335	COG0196	riboflavin kinase activity
AN947_RS09350	COG1047	Peptidyl-prolyl cis-trans
AN947_RS09355	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AN947_RS09360	COG1966	Carbon starvation protein
AN947_RS09375	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AN947_RS09380	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AN947_RS09390	COG3279	Response regulator of the LytR AlgR family
AN947_RS09395	COG3275	phosphorelay sensor kinase activity
AN947_RS09400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AN947_RS09405	COG0287	Prephenate dehydrogenase
AN947_RS09405	COG1605	Chorismate mutase
AN947_RS09415	COG0488	(ABC) transporter
AN947_RS09425	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AN947_RS09435	COG5001	Diguanylate cyclase
AN947_RS09440	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AN947_RS09445	COG1605	Chorismate mutase
AN947_RS09445	COG0077	Prephenate dehydratase
AN947_RS09450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AN947_RS09455	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AN947_RS09460	COG0564	pseudouridine synthase activity
AN947_RS09470	COG0542	response to heat
AN947_RS09515	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AN947_RS09520	COG0826	peptidase U32
AN947_RS09530	COG0745	RESPONSE REGULATOR receiver
AN947_RS09535	COG5002	protein histidine kinase activity
AN947_RS09545	COG0248	Ppx GppA phosphatase
AN947_RS09550	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AN947_RS09560	COG0581	inorganic phosphate transmembrane transporter activity
AN947_RS09565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AN947_RS09585	COG0450	alkyl hydroperoxide reductase
AN947_RS09590	COG0583	DNA-binding transcription factor activity
AN947_RS09605	COG0517	IMP dehydrogenase activity
AN947_RS09625	COG1862	Preprotein translocase
AN947_RS09630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AN947_RS09635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AN947_RS09640	COG0483	inositol monophosphate 1-phosphatase activity
AN947_RS09650	COG1959	2 iron, 2 sulfur cluster binding
AN947_RS09655	COG1104	cysteine desulfurase activity
AN947_RS09660	COG0822	iron-sulfur transferase activity
AN947_RS09670	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AN947_RS09675	COG0443	Heat shock 70 kDa protein
AN947_RS09680	COG0633	Ferredoxin
AN947_RS09685	COG2975	iron-sulfur cluster assembly
AN947_RS09690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AN947_RS09695	COG0105	UTP biosynthetic process
AN947_RS09700	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AN947_RS09710	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AN947_RS09715	COG0124	histidyl-tRNA synthetase
AN947_RS09720	COG2976	Protein conserved in bacteria
AN947_RS09725	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AN947_RS09730	COG1160	GTP binding
AN947_RS09745	COG1570	exodeoxyribonuclease VII activity
AN947_RS09750	COG0517	IMP dehydrogenase activity
AN947_RS09750	COG0516	GMP reductase activity
AN947_RS09755	COG0519	Catalyzes the synthesis of GMP from XMP
AN947_RS09755	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AN947_RS09765	COG1584	GPR1 FUN34 yaaH family protein
AN947_RS09770	COG1535	isochorismatase
AN947_RS09770	COG3433	isochorismatase activity
AN947_RS09775	COG1021	2,3-dihydroxybenzoate-AMP ligase
AN947_RS09780	COG1169	isochorismate synthase
AN947_RS09785	COG1028	Short-chain dehydrogenase reductase Sdr
AN947_RS09795	COG4592	Periplasmic binding protein
AN947_RS09800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN947_RS09805	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN947_RS09810	COG1120	ATPase activity
AN947_RS09820	COG0583	DNA-binding transcription factor activity
AN947_RS09825	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AN947_RS09830	COG1115	amino acid carrier protein
AN947_RS09840	COG0583	DNA-binding transcription factor activity
AN947_RS09855	COG4565	transcriptional regulatory protein
AN947_RS09865	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AN947_RS09870	COG5016	pyruvate
AN947_RS09870	COG0511	ligase activity, forming carbon-carbon bonds
AN947_RS09875	COG3630	sodium ion export across plasma membrane
AN947_RS09885	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AN947_RS09895	COG2301	Belongs to the HpcH HpaI aldolase family
AN947_RS09900	COG3051	citrate lyase alpha subunit
AN947_RS09920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN947_RS09925	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AN947_RS09930	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AN947_RS09995	COG1012	belongs to the aldehyde dehydrogenase family
AN947_RS10015	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AN947_RS10020	COG0840	transmembrane signaling receptor activity
AN947_RS10025	COG3710	Transcriptional regulator
AN947_RS10035	COG2165	general secretion pathway protein
AN947_RS10050	COG4796	Type ii and iii secretion system protein
AN947_RS10070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AN947_RS10075	COG1459	type II secretion system
AN947_RS10085	COG2207	Transcriptional regulator
AN947_RS10090	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AN947_RS10110	COG0739	heme binding
AN947_RS10120	COG3064	Membrane
AN947_RS10125	COG0582	viral genome integration into host DNA
AN947_RS10135	COG0582	viral genome integration into host DNA
AN947_RS10145	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AN947_RS10150	COG2867	negative regulation of translational initiation
AN947_RS10155	COG2914	Belongs to the UPF0125 (RnfH) family
AN947_RS10160	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AN947_RS10165	COG0497	DNA recombination
AN947_RS10170	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AN947_RS10175	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AN947_RS10180	COG0443	Heat shock 70 kDa protein
AN947_RS10185	COG0484	heat shock protein binding
AN947_RS10195	COG4968	Prepilin-type N-terminal cleavage methylation domain
AN947_RS10220	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AN947_RS10230	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AN947_RS10240	COG0047	phosphoribosylformylglycinamidine synthase activity
AN947_RS10240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AN947_RS10270	COG0442	prolyl-tRNA aminoacylation
AN947_RS10275	COG1720	tRNA m6t6A37 methyltransferase activity
AN947_RS10280	COG0254	rRNA binding
AN947_RS10285	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AN947_RS10290	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AN947_RS10295	COG1671	Belongs to the UPF0178 family
AN947_RS10305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN947_RS10320	COG3098	single-species biofilm formation
AN947_RS10325	COG0564	pseudouridine synthase activity
AN947_RS10330	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AN947_RS10335	COG0142	geranyltranstransferase activity
AN947_RS10340	COG1722	exodeoxyribonuclease VII activity
AN947_RS10345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AN947_RS10355	COG0301	tRNA thio-modification
AN947_RS10355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN947_RS10360	COG0583	DNA-binding transcription factor activity
AN947_RS10365	COG2363	Small membrane protein
AN947_RS10370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN947_RS10375	COG1611	Belongs to the LOG family
AN947_RS10390	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AN947_RS10390	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AN947_RS10400	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
AN947_RS10405	COG1464	Belongs to the NlpA lipoprotein family
AN947_RS10410	COG2011	ABC-type metal ion transport system permease component
AN947_RS10415	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AN947_RS10420	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AN947_RS10425	COG1609	Transcriptional regulator
AN947_RS10430	COG1263	PTS System
AN947_RS10430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN947_RS10435	COG0366	Alpha amylase catalytic
AN947_RS10470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AN947_RS10475	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AN947_RS10480	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AN947_RS10485	COG0110	maltose O-acetyltransferase activity
AN947_RS10505	COG1045	serine acetyltransferase
AN947_RS10515	COG0438	transferase activity, transferring glycosyl groups
AN947_RS10525	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AN947_RS10555	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AN947_RS10565	COG1596	polysaccharide export
AN947_RS10590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AN947_RS10605	COG0321	lipoyl(octanoyl) transferase activity
AN947_RS10610	COG2921	Belongs to the UPF0250 family
AN947_RS10615	COG1686	Belongs to the peptidase S11 family
AN947_RS10620	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AN947_RS10625	COG0772	Belongs to the SEDS family
AN947_RS10630	COG0768	penicillin binding
AN947_RS10635	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AN947_RS10640	COG0799	negative regulation of ribosome biogenesis
AN947_RS10645	COG1466	dna polymerase III delta subunit
AN947_RS10650	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AN947_RS10655	COG0495	leucyl-tRNA aminoacylation
AN947_RS10660	COG2888	peptidyl-tyrosine sulfation
AN947_RS10665	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AN947_RS10670	COG4535	Mg2 and Co2 transporter CorC
AN947_RS10680	COG1702	phosphate starvation-inducible protein PhoH
AN947_RS10685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AN947_RS10690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN947_RS10695	COG2190	(PTS) system
AN947_RS10705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN947_RS10715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AN947_RS10720	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AN947_RS10725	COG3115	cell septum assembly
AN947_RS10730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AN947_RS10745	COG0789	Transcriptional regulator
AN947_RS10750	COG1585	Membrane protein implicated in regulation of membrane protease activity
AN947_RS10755	COG0330	HflC and HflK could
AN947_RS10765	COG3118	belongs to the thioredoxin family
AN947_RS10770	COG0300	oxidoreductase activity
AN947_RS10775	COG1090	epimerase
AN947_RS10780	COG0622	Phosphoesterase
AN947_RS10795	COG3710	Transcriptional regulator
AN947_RS10800	COG0326	Molecular chaperone. Has ATPase activity
AN947_RS10805	COG0563	adenylate kinase activity
AN947_RS10810	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AN947_RS10825	COG0367	asparagine synthase
AN947_RS10830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AN947_RS10830	COG4651	solute:proton antiporter activity
AN947_RS10835	COG1846	Transcriptional regulator
AN947_RS10835	COG1940	carbohydrate kinase activity
AN947_RS10845	COG1263	PTS System
AN947_RS10845	COG2190	(PTS) system
AN947_RS10845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN947_RS10860	COG0101	tRNA pseudouridine synthase activity
AN947_RS10865	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AN947_RS10870	COG0285	dihydrofolate synthase activity
AN947_RS10875	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AN947_RS10880	COG1286	toxin biosynthetic process
AN947_RS10885	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AN947_RS10890	COG2056	Na+-H+ antiporter family
AN947_RS10895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AN947_RS10910	COG0346	lactoylglutathione lyase activity
AN947_RS10915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AN947_RS10935	COG4656	Part of a membrane complex involved in electron transport
AN947_RS10940	COG2878	Part of a membrane complex involved in electron transport
AN947_RS10945	COG4657	Part of a membrane complex involved in electron transport
AN947_RS10955	COG0556	nucleotide-excision repair
AN947_RS10965	COG2204	response regulator
AN947_RS10970	COG2198	Histidine kinase
AN947_RS10975	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AN947_RS10980	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AN947_RS10985	COG0521	Mo-molybdopterin cofactor biosynthetic process
AN947_RS10990	COG0315	cyclic pyranopterin monophosphate synthase activity
AN947_RS10995	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AN947_RS11000	COG0314	molybdopterin synthase activity
AN947_RS11005	COG2199	diguanylate cyclase activity
AN947_RS11010	COG0617	tRNA 3'-terminal CCA addition
AN947_RS11010	COG0517	IMP dehydrogenase activity
AN947_RS11010	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AN947_RS11025	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AN947_RS11035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN947_RS11035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN947_RS11040	COG0489	protein tyrosine kinase activity
AN947_RS11050	COG0572	uridine kinase
AN947_RS11055	COG2982	Protein involved in outer membrane biogenesis
AN947_RS11060	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AN947_RS11065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AN947_RS11095	COG0183	Belongs to the thiolase family
AN947_RS11100	COG1024	Enoyl-CoA hydratase
AN947_RS11100	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN947_RS11105	COG0778	Nitroreductase
AN947_RS11110	COG0583	DNA-binding transcription factor activity
AN947_RS11115	COG0745	RESPONSE REGULATOR receiver
AN947_RS11125	COG2832	Protein of unknown function (DUF454)
AN947_RS11130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AN947_RS11140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AN947_RS11145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AN947_RS11155	COG2983	Belongs to the UPF0260 family
AN947_RS11160	COG1028	Short-chain dehydrogenase reductase Sdr
AN947_RS11165	COG0616	signal peptide processing
AN947_RS11175	COG1522	sequence-specific DNA binding
AN947_RS11180	COG1946	Acyl-CoA thioesterase
AN947_RS11200	COG3706	GGDEF domain
AN947_RS11210	COG0640	Transcriptional regulator
AN947_RS11215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AN947_RS11240	COG1881	PFAM PEBP family protein
AN947_RS11260	COG0009	L-threonylcarbamoyladenylate synthase
AN947_RS11275	COG2201	protein-glutamate methylesterase activity
AN947_RS11285	COG5002	protein histidine kinase activity
AN947_RS11290	COG4191	Histidine kinase
AN947_RS11295	COG5001	Diguanylate cyclase
AN947_RS11295	COG3300	MHYT domain
AN947_RS11300	COG2204	response regulator
AN947_RS11320	COG0601	transmembrane transport
AN947_RS11325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN947_RS11330	COG0444	Belongs to the ABC transporter superfamily
AN947_RS11335	COG4608	Belongs to the ABC transporter superfamily
AN947_RS11340	COG0435	Glutathione S-transferase
AN947_RS11345	COG0280	phosphate acetyltransferase
AN947_RS11345	COG0857	belongs to the CobB CobQ family
AN947_RS11350	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AN947_RS11355	COG3092	negative regulation of chromosome organization
AN947_RS11360	COG4628	conserved protein (DUF2132)
AN947_RS11370	COG4120	Belongs to the binding-protein-dependent transport system permease family
AN947_RS11380	COG2203	Gaf domain
AN947_RS11380	COG2199	diguanylate cyclase activity
AN947_RS11385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AN947_RS11395	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AN947_RS11400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AN947_RS11405	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AN947_RS11415	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AN947_RS11420	COG0156	8-amino-7-oxononanoate synthase activity
AN947_RS11425	COG2226	methyltransferase
AN947_RS11430	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AN947_RS11465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AN947_RS11475	COG2268	Band 7 protein
AN947_RS11485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AN947_RS11490	COG2915	High frequency lysogenization protein hflD homolog
AN947_RS11500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN947_RS11505	COG2916	Histone family protein nucleoid-structuring protein H-NS
AN947_RS11510	COG1757	Na H antiporter
AN947_RS11515	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AN947_RS11520	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AN947_RS11525	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AN947_RS11530	COG0131	Imidazoleglycerol-phosphate dehydratase
AN947_RS11530	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AN947_RS11535	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AN947_RS11540	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AN947_RS11545	COG0107	imidazoleglycerol-phosphate synthase activity
AN947_RS11550	COG0140	phosphoribosyl-ATP diphosphatase activity
AN947_RS11550	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AN947_RS11555	COG1187	pseudouridine synthase activity
AN947_RS11565	COG1278	Cold shock
AN947_RS11570	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AN947_RS11575	COG0542	response to heat
AN947_RS11580	COG3273	potassium ion transport
AN947_RS11580	COG2985	domain, Protein
AN947_RS11585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AN947_RS11590	COG1012	belongs to the aldehyde dehydrogenase family
AN947_RS11590	COG1454	alcohol dehydrogenase
AN947_RS11595	COG1737	Transcriptional regulator
AN947_RS11600	COG0076	glutamate decarboxylase activity
AN947_RS11610	COG2431	L-lysine efflux transmembrane transporter activity
AN947_RS11620	COG3070	regulator of competence-specific genes
AN947_RS11635	COG3852	Histidine kinase
AN947_RS11645	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AN947_RS11660	COG0189	ligase activity
AN947_RS11660	COG4067	protein conserved in archaea
AN947_RS11665	COG0500	methyltransferase
AN947_RS11670	COG4106	trans-aconitate 2-methyltransferase activity
AN947_RS11675	COG1801	Protein of unknown function DUF72
AN947_RS11680	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AN947_RS11685	COG1435	thymidine kinase activity
AN947_RS11695	COG0159	tryptophan synthase activity
AN947_RS11700	COG0133	tryptophan synthase activity
AN947_RS11705	COG0134	indole-3-glycerol-phosphate synthase activity
AN947_RS11705	COG0135	phosphoribosylanthranilate isomerase activity
AN947_RS11710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AN947_RS11715	COG0512	Glutamine amidotransferase of anthranilate synthase
AN947_RS11720	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AN947_RS11730	COG0613	PHP domain protein
AN947_RS11735	COG0009	L-threonylcarbamoyladenylate synthase
AN947_RS11740	COG1187	pseudouridine synthase activity
AN947_RS11745	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AN947_RS11750	COG4988	ABC transporter
AN947_RS11755	COG0492	ferredoxin-NADP+ reductase activity
AN947_RS11765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AN947_RS11770	COG3706	GGDEF domain
AN947_RS11775	COG2949	membrane
AN947_RS11785	COG0281	malic enzyme
AN947_RS11795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AN947_RS11815	COG2885	chlorophyll binding
AN947_RS11830	COG0277	FAD linked oxidase domain protein
AN947_RS11830	COG0247	lactate metabolic process
AN947_RS11850	COG2986	histidine ammonia-lyase
AN947_RS11855	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AN947_RS11860	COG0010	Belongs to the arginase family
AN947_RS11865	COG1228	amidohydrolase
AN947_RS11880	COG3099	Belongs to the UPF0263 family
AN947_RS11885	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AN947_RS11895	COG5001	Diguanylate cyclase
AN947_RS11900	COG0417	DNA replication proofreading
AN947_RS11905	COG2197	response regulator
AN947_RS11910	COG0322	excinuclease ABC activity
AN947_RS11950	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AN947_RS11955	COG0072	phenylalanine-tRNA ligase activity
AN947_RS11955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN947_RS12000	COG1346	cytolysis
AN947_RS12005	COG1380	Effector of murein hydrolase LrgA
AN947_RS12010	COG2925	Exonuclease
AN947_RS12015	COG1823	symporter activity
AN947_RS12020	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AN947_RS12030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AN947_RS12035	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AN947_RS12055	COG4139	cobalamin transport
AN947_RS12110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AN947_RS12115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AN947_RS12120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AN947_RS12130	COG1054	Belongs to the UPF0176 family
AN947_RS12140	COG2814	Major facilitator Superfamily
AN947_RS12150	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AN947_RS12175	COG2989	Protein conserved in bacteria
AN947_RS12180	COG3108	Peptidase M15
AN947_RS12185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN947_RS12200	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AN947_RS12230	COG1846	Transcriptional regulator
AN947_RS12235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AN947_RS12240	COG0726	polysaccharide deacetylase
AN947_RS12245	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN947_RS12255	COG1447	Phosphotransferase system cellobiose-specific component IIA
AN947_RS12260	COG1486	melibiose metabolic process
AN947_RS12270	COG1609	Transcriptional regulator
AN947_RS12275	COG2943	transferase activity, transferring hexosyl groups
AN947_RS12280	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AN947_RS12285	COG0840	transmembrane signaling receptor activity
AN947_RS12300	COG1448	Aminotransferase
AN947_RS12310	COG2770	Histidine kinase
AN947_RS12310	COG3437	response regulator, receiver
AN947_RS12315	COG0351	phosphomethylpyrimidine kinase
AN947_RS12320	COG0017	Asparaginyl-tRNA synthetase
AN947_RS12330	COG0720	synthase
AN947_RS12335	COG1760	l-serine dehydratase
AN947_RS12340	COG0814	amino acid
AN947_RS12345	COG0494	nUDIX hydrolase
AN947_RS12350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AN947_RS12365	COG3106	COG3106 Predicted ATPase
AN947_RS12370	COG3768	UPF0283 membrane protein
AN947_RS12380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN947_RS12395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AN947_RS12405	COG0471	metal ion transport
AN947_RS12410	COG4191	Histidine kinase
AN947_RS12410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN947_RS12420	COG2990	Protein conserved in bacteria
AN947_RS12430	COG2205	protein histidine kinase activity
AN947_RS12435	COG0745	RESPONSE REGULATOR receiver
AN947_RS12505	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AN947_RS12510	COG0372	Belongs to the citrate synthase family
AN947_RS12540	COG2195	Cleaves the N-terminal amino acid of tripeptides
AN947_RS12550	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AN947_RS12560	COG0625	glutathione transferase activity
AN947_RS12565	COG3437	response regulator, receiver
AN947_RS12590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AN947_RS12595	COG1254	Belongs to the acylphosphatase family
AN947_RS12600	COG2920	part of a sulfur-relay system
AN947_RS12605	COG0670	Belongs to the BI1 family
AN947_RS12610	COG1126	abc transporter atp-binding protein
AN947_RS12615	COG0765	amino acid transport
AN947_RS12620	COG4597	amino acid ABC transporter
AN947_RS12625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN947_RS12635	COG0561	phosphatase activity
AN947_RS12640	COG0602	queuosine metabolic process
AN947_RS12645	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AN947_RS12675	COG3706	GGDEF domain
AN947_RS12680	COG0443	Heat shock 70 kDa protein
AN947_RS12685	COG0443	Heat shock 70 kDa protein
AN947_RS12720	COG1643	Atp-dependent helicase
AN947_RS12730	COG0443	Heat shock 70 kDa protein
AN947_RS12735	COG0095	Lipoate-protein ligase
AN947_RS12745	COG0583	DNA-binding transcription factor activity
AN947_RS12750	COG0477	Major facilitator Superfamily
AN947_RS12755	COG0415	Belongs to the DNA photolyase family
AN947_RS12770	COG0745	RESPONSE REGULATOR receiver
AN947_RS12785	COG2198	Histidine kinase
AN947_RS12785	COG0643	Histidine kinase
AN947_RS12785	COG0784	Response regulator, receiver
AN947_RS12800	COG2201	protein-glutamate methylesterase activity
AN947_RS12805	COG0835	chemotaxis
AN947_RS12810	COG0840	transmembrane signaling receptor activity
AN947_RS12810	COG3290	protein histidine kinase activity
AN947_RS12815	COG0840	transmembrane signaling receptor activity
AN947_RS12825	COG0513	Belongs to the DEAD box helicase family
AN947_RS12835	COG1538	Outer membrane efflux protein
AN947_RS12840	COG1566	PFAM secretion protein HlyD family protein
AN947_RS12845	COG2814	Major facilitator Superfamily
AN947_RS12855	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AN947_RS12865	COG3501	Rhs element vgr protein
AN947_RS12890	COG1280	lysine exporter protein (LysE YggA)
AN947_RS12895	COG1115	amino acid carrier protein
AN947_RS12910	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AN947_RS12920	COG1177	transmembrane transport
AN947_RS12930	COG3842	ATPase activity
AN947_RS12955	COG0589	response to stress
AN947_RS12960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AN947_RS12975	COG2217	Heavy metal translocating P-type atpase
AN947_RS12985	COG2010	Cytochrome c
AN947_RS13000	COG3278	Belongs to the heme-copper respiratory oxidase family
AN947_RS13015	COG0784	Response regulator, receiver
AN947_RS13015	COG2205	protein histidine kinase activity
AN947_RS13040	COG2994	toxin metabolic process
AN947_RS13045	COG1073	alpha beta
AN947_RS13045	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AN947_RS13045	COG3064	Membrane
AN947_RS13050	COG4128	Pfam Zonular occludens toxin
AN947_RS13100	COG4128	Pfam Zonular occludens toxin
AN947_RS13130	COG1476	TRANSCRIPTIONal
AN947_RS13150	COG4128	Pfam Zonular occludens toxin
AN947_RS13280	COG3120	sequence-specific DNA binding
AN947_RS13285	COG1067	ATP-dependent peptidase activity
AN947_RS13290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AN947_RS13305	COG0488	(ABC) transporter
AN947_RS13315	COG0116	Belongs to the methyltransferase superfamily
AN947_RS13315	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AN947_RS13325	COG0167	dihydroorotate dehydrogenase activity
AN947_RS13340	COG0308	aminopeptidase N
AN947_RS13360	COG1956	GAF domain-containing protein
AN947_RS13365	COG1132	(ABC) transporter
AN947_RS13370	COG2995	paraquat-inducible protein a
AN947_RS13375	COG3008	intermembrane lipid transfer
AN947_RS13385	COG2996	Protein conserved in bacteria
AN947_RS13400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AN947_RS13405	COG1666	GTP binding
AN947_RS13410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AN947_RS13425	COG0437	4 iron, 4 sulfur cluster binding
AN947_RS13430	COG0243	molybdopterin cofactor binding
AN947_RS13430	COG3383	formate dehydrogenase (NAD+) activity
AN947_RS13460	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AN947_RS13465	COG0488	(ABC) transporter
AN947_RS13470	COG3852	Histidine kinase
AN947_RS13475	COG2204	response regulator
AN947_RS13485	COG4662	Binding-protein-dependent transport system inner membrane component
AN947_RS13490	COG3842	ATPase activity
AN947_RS13495	COG0746	molybdenum cofactor guanylyltransferase activity
AN947_RS13530	COG1940	carbohydrate kinase activity
AN947_RS13535	COG3148	PFAM DTW domain containing protein
AN947_RS13545	COG0840	transmembrane signaling receptor activity
AN947_RS13550	COG0791	NLP P60 protein
AN947_RS13560	COG3001	Fructosamine kinase
AN947_RS13570	COG0534	Mate efflux family protein
AN947_RS13580	COG1793	dna ligase
AN947_RS13595	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AN947_RS13600	COG0848	biopolymer transport protein
AN947_RS13605	COG0811	peptide transport
AN947_RS13610	COG0811	peptide transport
AN947_RS13625	COG1175	transmembrane transport
AN947_RS13630	COG0395	ABC-type sugar transport system, permease component
AN947_RS13640	COG1349	DNA-binding transcription factor activity
AN947_RS13645	COG0584	glycerophosphoryl diester phosphodiesterase
AN947_RS13650	COG2731	YhcH YjgK YiaL family protein
AN947_RS13655	COG0251	oxidation-reduction process
AN947_RS13660	COG1609	Transcriptional regulator
AN947_RS13665	COG2723	6-phospho-beta-galactosidase activity
AN947_RS13675	COG0583	DNA-binding transcription factor activity
AN947_RS13695	COG1136	(ABC) transporter
AN947_RS13695	COG0577	efflux transmembrane transporter activity
AN947_RS13700	COG0577	efflux transmembrane transporter activity
AN947_RS13700	COG1136	(ABC) transporter
AN947_RS13705	COG4591	ABC-type transport system involved in lipoprotein release permease component
AN947_RS13705	COG1136	(ABC) transporter
AN947_RS13710	COG1294	oxidase, subunit
AN947_RS13715	COG1271	oxidase subunit
AN947_RS13760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN947_RS13770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AN947_RS13790	COG0753	catalase activity
AN947_RS13805	COG3527	Alpha-acetolactate decarboxylase
AN947_RS13820	COG2200	EAL domain
AN947_RS13820	COG2199	diguanylate cyclase activity
AN947_RS13835	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AN947_RS13840	COG1085	galactose-1-phosphate uridylyltransferase
AN947_RS13895	COG4565	transcriptional regulatory protein
AN947_RS13900	COG3290	protein histidine kinase activity
AN947_RS13915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN947_RS13935	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AN947_RS13940	COG3063	Type IV pilus biogenesis stability protein PilW
AN947_RS13955	COG1451	nucleotide metabolic process
AN947_RS13965	COG0583	DNA-binding transcription factor activity
AN947_RS14000	COG1748	Saccharopine dehydrogenase
AN947_RS14015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AN947_RS14025	COG0577	efflux transmembrane transporter activity
AN947_RS14035	COG0534	Mate efflux family protein
AN947_RS14050	COG2814	Major facilitator Superfamily
AN947_RS14055	COG1187	pseudouridine synthase activity
AN947_RS14060	COG1061	Type III restriction enzyme res subunit
AN947_RS14080	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AN947_RS14085	COG2203	Gaf domain
AN947_RS14085	COG3706	GGDEF domain
AN947_RS14085	COG4251	negative regulation of phosphorylation
AN947_RS14085	COG5001	Diguanylate cyclase
AN947_RS14100	COG0840	transmembrane signaling receptor activity
AN947_RS14130	COG4934	collagen metabolic process
AN947_RS14145	COG0784	Response regulator, receiver
AN947_RS14145	COG2205	protein histidine kinase activity
AN947_RS14150	COG2239	Acts as a magnesium transporter
AN947_RS14160	COG0814	amino acid
AN947_RS14165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN947_RS14170	COG1131	(ABC) transporter
AN947_RS14175	COG0842	Transport permease protein
AN947_RS14185	COG3313	Fe-S protein
AN947_RS14195	COG4134	Bacterial extracellular solute-binding protein
AN947_RS14200	COG4135	transport system, permease component
AN947_RS14205	COG4136	ATPase activity
AN947_RS14215	COG0564	pseudouridine synthase activity
AN947_RS14220	COG0733	neurotransmitter:sodium symporter activity
AN947_RS14235	COG0626	cystathionine gamma-synthase activity
AN947_RS14240	COG2818	Glycosylase
AN947_RS14255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN947_RS14270	COG1842	Phage shock protein A
AN947_RS14275	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AN947_RS14285	COG4168	peptide transport system, permease
AN947_RS14300	COG4172	Belongs to the ABC transporter superfamily
AN947_RS14315	COG1227	inorganic diphosphatase activity
AN947_RS14340	COG0243	molybdopterin cofactor binding
AN947_RS14345	COG3005	denitrification pathway
AN947_RS14350	COG4459	periplasmic nitrate reductase
AN947_RS14360	COG2116	formate transmembrane transporter activity
AN947_RS14375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN947_RS14380	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AN947_RS14400	COG2350	Protein conserved in bacteria
AN947_RS14410	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AN947_RS14415	COG0583	DNA-binding transcription factor activity
AN947_RS14430	COG0612	Peptidase, M16
AN947_RS14435	COG5001	Diguanylate cyclase
AN947_RS14440	COG1032	radical SAM domain protein
AN947_RS14460	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AN947_RS14470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AN947_RS14475	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AN947_RS14480	COG0745	RESPONSE REGULATOR receiver
AN947_RS14485	COG3381	protein complex oligomerization
AN947_RS14495	COG1609	Transcriptional regulator
AN947_RS14500	COG3070	regulator of competence-specific genes
AN947_RS14520	COG0297	glycogen (starch) synthase activity
AN947_RS14525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AN947_RS14530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AN947_RS14560	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AN947_RS14570	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AN947_RS14600	COG1309	transcriptional regulator
AN947_RS14625	COG0668	transmembrane transport
AN947_RS14635	COG3008	intermembrane lipid transfer
AN947_RS14635	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AN947_RS14645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN947_RS14660	COG0582	viral genome integration into host DNA
AN947_RS14665	COG0582	viral genome integration into host DNA
AN947_RS14670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AN947_RS14680	COG3941	tape measure
AN947_RS14725	COG0488	(ABC) transporter
AN947_RS14805	COG0415	Belongs to the DNA photolyase family
AN947_RS14815	COG4628	conserved protein (DUF2132)
AN947_RS14820	COG3284	Transcriptional regulator
AN947_RS14825	COG1012	belongs to the aldehyde dehydrogenase family
AN947_RS14835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN947_RS14840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN947_RS14845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN947_RS14855	COG2207	Transcriptional regulator
AN947_RS14860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN947_RS14860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN947_RS14860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN947_RS14865	COG1482	cell wall glycoprotein biosynthetic process
AN947_RS14875	COG5002	protein histidine kinase activity
AN947_RS14875	COG0784	Response regulator, receiver
AN947_RS14885	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AN947_RS14895	COG2885	chlorophyll binding
AN947_RS14900	COG0823	Involved in the tonB-independent uptake of proteins
AN947_RS14915	COG0811	peptide transport
AN947_RS14920	COG0824	Thioesterase
AN947_RS14925	COG3790	cyd operon protein YbgE
AN947_RS14930	COG4890	Cyd operon protein YbgT
AN947_RS14935	COG1294	oxidase, subunit
AN947_RS14940	COG1271	oxidase subunit
AN947_RS14950	COG0632	four-way junction helicase activity
AN947_RS14955	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AN947_RS14960	COG0215	cysteine-tRNA ligase activity
AN947_RS14965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AN947_RS14975	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AN947_RS14980	COG3012	SEC-C Motif Domain Protein
AN947_RS14985	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AN947_RS14990	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AN947_RS14995	COG1199	ATP-dependent helicase activity
AN947_RS15000	COG0730	response to heat
AN947_RS15005	COG3923	Primosomal replication protein n
AN947_RS15015	COG0840	transmembrane signaling receptor activity
AN947_RS15020	COG0708	Exodeoxyribonuclease III
AN947_RS15025	COG4160	amino acid transport
AN947_RS15055	COG1882	Formate acetyltransferase
AN947_RS15065	COG0840	transmembrane signaling receptor activity
AN947_RS15070	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AN947_RS15080	COG3013	Belongs to the UPF0304 family
AN947_RS15085	COG2766	serine protein kinase
AN947_RS15090	COG2718	Belongs to the UPF0229 family
AN947_RS15095	COG2719	SpoVR family
AN947_RS15100	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AN947_RS15105	COG2835	tetraacyldisaccharide 4'-kinase activity
AN947_RS15110	COG1663	tetraacyldisaccharide 4'-kinase activity
AN947_RS15115	COG1132	(ABC) transporter
AN947_RS15120	COG2333	competence protein COMEC
AN947_RS15120	COG0658	competence protein
AN947_RS15130	COG4591	ABC-type transport system involved in lipoprotein release permease component
AN947_RS15135	COG1136	(ABC) transporter
AN947_RS15140	COG4591	ABC-type transport system involved in lipoprotein release permease component
AN947_RS15150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AN947_RS15170	COG1252	NADH dehydrogenase
AN947_RS15175	COG3150	esterase
AN947_RS15200	COG0537	adenosine 5'-monophosphoramidase activity
AN947_RS15215	COG2186	Transcriptional regulator
AN947_RS15220	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AN947_RS15225	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AN947_RS15230	COG1674	ftsk spoiiie
AN947_RS15240	COG0686	Belongs to the AlaDH PNT family
AN947_RS15250	COG0583	DNA-binding transcription factor activity
AN947_RS15270	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AN947_RS15275	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AN947_RS15280	COG0776	regulation of translation
AN947_RS15285	COG0539	negative regulation of cytoplasmic translation
AN947_RS15290	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AN947_RS15295	COG1555	photosystem II stabilization
AN947_RS15300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AN947_RS15305	COG0776	regulation of translation
AN947_RS15310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AN947_RS15315	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AN947_RS15325	COG0544	peptidyl-prolyl cis-trans isomerase activity
AN947_RS15345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AN947_RS15350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AN947_RS15355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AN947_RS15360	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AN947_RS15375	COG5001	Diguanylate cyclase
AN947_RS15375	COG3300	MHYT domain
AN947_RS15385	COG4589	Belongs to the CDS family
AN947_RS15425	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AN947_RS15435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN947_RS15455	COG0243	molybdopterin cofactor binding
AN947_RS15460	COG3005	denitrification pathway
AN947_RS15465	COG3325	Belongs to the glycosyl hydrolase 18 family
AN947_RS15465	COG3469	chitinase activity
AN947_RS15470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AN947_RS15480	COG2951	lytic endotransglycosylase activity
AN947_RS15485	COG3100	YcgL domain-containing protein
AN947_RS15490	COG0850	regulation of cytokinetic process
AN947_RS15495	COG2894	cell division
AN947_RS15500	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AN947_RS15505	COG3015	lipoprotein NlpE involved in copper resistance
AN947_RS15530	COG0840	transmembrane signaling receptor activity
AN947_RS15535	COG1396	sequence-specific DNA binding
AN947_RS15540	COG3135	benzoate transporter
AN947_RS15560	COG0596	Alpha beta hydrolase
AN947_RS15565	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AN947_RS15570	COG1169	isochorismate synthase
AN947_RS15575	COG0436	Aminotransferase
AN947_RS15580	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AN947_RS15585	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AN947_RS15605	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AN947_RS15610	COG0318	PFAM AMP-dependent synthetase and ligase
AN947_RS15615	COG0596	Alpha beta hydrolase
AN947_RS15630	COG1214	PFAM Peptidase M22, glycoprotease
AN947_RS15635	COG1199	ATP-dependent helicase activity
AN947_RS15645	COG0788	formyltetrahydrofolate deformylase activity
AN947_RS15650	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN947_RS15650	COG1902	pentaerythritol trinitrate reductase activity
AN947_RS15655	COG0616	signal peptide processing
AN947_RS15660	COG0252	asparaginase activity
AN947_RS15665	COG3139	Protein of unknown function (DUF1315)
AN947_RS15675	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AN947_RS15680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AN947_RS15705	COG2226	methyltransferase
AN947_RS15720	COG0784	Response regulator, receiver
AN947_RS15720	COG0835	chemotaxis
AN947_RS15725	COG1940	carbohydrate kinase activity
AN947_RS15750	COG0733	neurotransmitter:sodium symporter activity
AN947_RS15760	COG1263	PTS System
AN947_RS15760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN947_RS15765	COG0084	hydrolase, TatD family'
AN947_RS15775	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AN947_RS15780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AN947_RS15785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN947_RS15790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AN947_RS15795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN947_RS15800	COG1028	Short-chain dehydrogenase reductase Sdr
AN947_RS15810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AN947_RS15815	COG0416	fatty acid biosynthetic process
AN947_RS15820	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AN947_RS15825	COG1399	metal-binding, possibly nucleic acid-binding protein
AN947_RS15830	COG0424	maF-like protein
AN947_RS15835	COG0564	pseudouridine synthase activity
AN947_RS15850	COG1530	ribonuclease E activity
AN947_RS15870	COG1454	alcohol dehydrogenase
AN947_RS15870	COG1012	belongs to the aldehyde dehydrogenase family
AN947_RS15875	COG2095	MarC family integral membrane protein
AN947_RS15880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AN947_RS15885	COG1757	Na H antiporter
AN947_RS15895	COG3081	Nucleoid-associated protein
AN947_RS15900	COG3082	Protein of unknown function (DUF1414)
AN947_RS15905	COG3083	sulfuric ester hydrolase activity
AN947_RS15920	COG0123	including yeast histone deacetylase and acetoin utilization protein
AN947_RS15930	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AN947_RS15950	COG2853	Lipoprotein
AN947_RS15960	COG4235	cytochrome complex assembly
AN947_RS15960	COG3088	subunit of a heme lyase
AN947_RS15965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN947_RS15970	COG1138	Cytochrome C-type biogenesis protein
AN947_RS15975	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AN947_RS15985	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AN947_RS15990	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AN947_RS15995	COG4133	protoheme IX ABC transporter activity
AN947_RS16005	COG0835	chemotaxis
AN947_RS16015	COG1192	Involved in chromosome partitioning
AN947_RS16020	COG2201	protein-glutamate methylesterase activity
AN947_RS16025	COG0784	Response regulator, receiver
AN947_RS16025	COG0643	Histidine kinase
AN947_RS16025	COG2198	Histidine kinase
AN947_RS16030	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AN947_RS16060	COG2062	phosphohistidine phosphatase, SixA
AN947_RS16065	COG1025	Belongs to the peptidase M16 family
AN947_RS16075	COG0018	arginyl-trna synthetase
AN947_RS16095	COG1918	ferrous iron import across plasma membrane
AN947_RS16100	COG4977	sequence-specific DNA binding
AN947_RS16105	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AN947_RS16110	COG1121	(ABC) transporter
AN947_RS16115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN947_RS16125	COG0045	succinate-CoA ligase (ADP-forming) activity
AN947_RS16130	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN947_RS16135	COG0567	Dehydrogenase, E1 component
AN947_RS16145	COG1053	succinate dehydrogenase
AN947_RS16150	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AN947_RS16155	COG2009	succinate dehydrogenase
AN947_RS16160	COG0372	Belongs to the citrate synthase family
AN947_RS16165	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AN947_RS16180	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AN947_RS16185	COG0596	Alpha beta hydrolase
AN947_RS16200	COG1346	cytolysis
AN947_RS16210	COG0583	DNA-binding transcription factor activity
AN947_RS16220	COG0735	belongs to the Fur family
AN947_RS16225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AN947_RS16230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AN947_RS16235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AN947_RS16245	COG0431	NADPH-dependent FMN reductase
AN947_RS16255	COG3101	peptidyl-lysine hydroxylation
AN947_RS16260	COG2860	membrane
AN947_RS16265	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AN947_RS16275	COG2890	protein-(glutamine-N5) methyltransferase activity
AN947_RS16280	COG2840	Smr protein MutS2
AN947_RS16290	COG1684	flagellar biosynthetic protein fliR
AN947_RS16295	COG1987	bacterial-type flagellum assembly
AN947_RS16320	COG1580	Controls the rotational direction of flagella during chemotaxis
AN947_RS16345	COG1317	bacterial-type flagellum organization
AN947_RS16350	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AN947_RS16360	COG1677	Flagellar hook-basal body complex protein FliE
AN947_RS16380	COG1516	flagellar protein fliS
AN947_RS16390	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AN947_RS16395	COG1334	flagellar protein FlaG
AN947_RS16400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AN947_RS16405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AN947_RS16410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AN947_RS16415	COG2837	iron assimilation
AN947_RS16435	COG1393	Belongs to the ArsC family
AN947_RS16445	COG1876	peptidase activity
AN947_RS16455	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AN947_RS16470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AN947_RS16490	COG4783	chaperone-mediated protein folding
AN947_RS16495	COG1393	Belongs to the ArsC family
AN947_RS16515	COG2233	PERMEase
AN947_RS16520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AN947_RS16525	COG0737	Belongs to the 5'-nucleotidase family
AN947_RS16530	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AN947_RS16535	COG2912	Transglutaminase-like superfamily
AN947_RS16545	COG2890	protein-(glutamine-N5) methyltransferase activity
AN947_RS16550	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AN947_RS16555	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AN947_RS16560	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AN947_RS16570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AN947_RS16575	COG0193	aminoacyl-tRNA hydrolase activity
AN947_RS16580	COG0012	GTP binding
AN947_RS16655	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AN947_RS16660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AN947_RS16675	COG1705	Flagellar rod assembly protein muramidase FlgJ
AN947_RS16675	COG3951	Flagellar rod assembly protein muramidase FlgJ
AN947_RS16680	COG1706	bacterial-type flagellum-dependent cell motility
AN947_RS16685	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AN947_RS16695	COG4787	bacterial-type flagellum-dependent cell motility
AN947_RS16700	COG1749	Flagellar hook protein flgE
AN947_RS16715	COG1815	bacterial-type flagellum-dependent cell motility
AN947_RS16720	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AN947_RS16725	COG0784	Response regulator, receiver
AN947_RS16725	COG0835	chemotaxis
AN947_RS16760	COG2226	methyltransferase
AN947_RS16760	COG3433	isochorismatase activity
AN947_RS16760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN947_RS16765	COG2375	cellular response to nickel ion
AN947_RS16770	COG1629	transport
AN947_RS16770	COG4774	siderophore transport
AN947_RS16785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AN947_RS16790	COG2608	mercury ion transmembrane transporter activity
AN947_RS16790	COG2217	Heavy metal translocating P-type atpase
AN947_RS16805	COG3735	TraB family
AN947_RS16820	COG2840	Smr protein MutS2
AN947_RS16825	COG1187	pseudouridine synthase activity
AN947_RS16835	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AN947_RS16840	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AN947_RS16845	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AN947_RS16850	COG0121	glutamine amidotransferase
AN947_RS16855	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AN947_RS16860	COG1960	acyl-CoA dehydrogenase activity
AN947_RS16875	COG0328	RNA-DNA hybrid ribonuclease activity
AN947_RS16880	COG2226	methyltransferase
AN947_RS16885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN947_RS16895	COG3021	interspecies interaction between organisms
AN947_RS16900	COG0347	Belongs to the P(II) protein family
AN947_RS16905	COG3479	Phenolic acid decarboxylase
AN947_RS16915	COG0037	tRNA processing
AN947_RS16920	COG0825	malonyl-CoA metabolic process
AN947_RS16925	COG0587	DNA-directed DNA polymerase activity
AN947_RS16930	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AN947_RS16935	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AN947_RS16940	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AN947_RS16945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AN947_RS16950	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AN947_RS16955	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AN947_RS16970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AN947_RS16975	COG0575	Belongs to the CDS family
AN947_RS16980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AN947_RS16985	COG0233	cytoplasmic translational termination
AN947_RS16990	COG0528	UMP kinase activity
AN947_RS16995	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AN947_RS17000	COG0052	Belongs to the universal ribosomal protein uS2 family
AN947_RS17005	COG0024	Methionine aminopeptidase
AN947_RS17010	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AN947_RS17020	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AN947_RS17025	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AN947_RS17030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AN947_RS17035	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AN947_RS17050	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AN947_RS17050	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AN947_RS17055	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AN947_RS17060	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AN947_RS17065	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AN947_RS17075	COG1073	alpha beta
AN947_RS17080	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AN947_RS17085	COG2252	PERMEase
AN947_RS17090	COG2195	Cleaves the N-terminal amino acid of tripeptides
AN947_RS17095	COG4067	protein conserved in archaea
AN947_RS17095	COG0189	ligase activity
AN947_RS17100	COG0189	ligase activity
AN947_RS17110	COG0733	neurotransmitter:sodium symporter activity
AN947_RS17135	COG1477	protein flavinylation
AN947_RS17140	COG2871	sodium ion transport
AN947_RS17145	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AN947_RS17150	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AN947_RS17155	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AN947_RS17160	COG1805	sodium ion transport
AN947_RS17165	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AN947_RS17170	COG0271	Belongs to the BolA IbaG family
AN947_RS17175	COG2813	Specifically methylates the guanine in position
AN947_RS17185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AN947_RS17195	COG2211	Major facilitator Superfamily
AN947_RS17205	COG1595	DNA-templated transcription, initiation
AN947_RS17215	COG3248	Nucleoside-binding outer membrane protein
AN947_RS17220	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AN947_RS17225	COG0693	protein deglycase activity
AN947_RS17230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AN947_RS17235	COG2166	iron-sulfur cluster assembly
AN947_RS17240	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AN947_RS17245	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AN947_RS17255	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AN947_RS17255	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AN947_RS17265	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AN947_RS17270	COG1074	ATP-dependent DNA helicase activity
AN947_RS17275	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AN947_RS17290	COG3141	response to X-ray
AN947_RS17305	COG0456	acetyltransferase
AN947_RS17310	COG0189	ligase activity
AN947_RS17310	COG0569	domain protein
AN947_RS17325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN947_RS17330	COG1609	Transcriptional regulator
AN947_RS17335	COG3250	beta-galactosidase activity
AN947_RS17350	COG1022	Amp-dependent synthetase and ligase
AN947_RS17355	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AN947_RS17360	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AN947_RS17375	COG0560	Phosphoserine phosphatase
AN947_RS17385	COG0813	purine-nucleoside phosphorylase activity
AN947_RS17390	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AN947_RS17395	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AN947_RS17400	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AN947_RS17410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AN947_RS17415	COG0084	hydrolase, TatD family'
AN947_RS17420	COG3022	response to hydroperoxide
AN947_RS17425	COG1115	amino acid carrier protein
AN947_RS17440	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AN947_RS17445	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AN947_RS17450	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
AN947_RS17455	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AN947_RS17480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AN947_RS17490	COG0745	RESPONSE REGULATOR receiver
AN947_RS17495	COG0784	Response regulator, receiver
AN947_RS17495	COG5002	protein histidine kinase activity
AN947_RS17495	COG2198	Histidine kinase
AN947_RS17500	COG3706	GGDEF domain
AN947_RS17500	COG4251	negative regulation of phosphorylation
AN947_RS17500	COG5001	Diguanylate cyclase
AN947_RS17500	COG2203	Gaf domain
AN947_RS17505	COG1242	4 iron, 4 sulfur cluster binding
AN947_RS17510	COG0067	glutamate synthase
AN947_RS17510	COG0069	glutamate synthase activity
AN947_RS17510	COG0070	glutamate synthase
AN947_RS17520	COG0069	glutamate synthase activity
AN947_RS17520	COG0067	glutamate synthase
AN947_RS17520	COG0070	glutamate synthase
AN947_RS17525	COG0493	'glutamate synthase
AN947_RS17535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AN947_RS17545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN947_RS17550	COG2860	membrane
AN947_RS17555	COG0583	DNA-binding transcription factor activity
AN947_RS17560	COG0730	response to heat
AN947_RS17570	COG4172	Belongs to the ABC transporter superfamily
AN947_RS17590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AN947_RS17595	COG0505	Belongs to the CarA family
AN947_RS17605	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AN947_RS17610	COG0494	nUDIX hydrolase
AN947_RS17615	COG0653	protein targeting
AN947_RS17625	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AN947_RS17630	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AN947_RS17640	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AN947_RS17645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AN947_RS17655	COG0772	Belongs to the SEDS family
AN947_RS17660	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AN947_RS17670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AN947_RS17675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AN947_RS17680	COG0768	penicillin binding
AN947_RS17685	COG3116	cell division
AN947_RS17700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN947_RS17705	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN947_RS17710	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AN947_RS17715	COG2186	Transcriptional regulator
AN947_RS17725	COG0737	Belongs to the 5'-nucleotidase family
AN947_RS17730	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AN947_RS17735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN947_RS17740	COG4974	Belongs to the 'phage' integrase family
AN947_RS17745	COG0716	FMN binding
AN947_RS17765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AN947_RS17770	COG1459	type II secretion system
AN947_RS17780	COG0237	dephospho-CoA kinase activity
AN947_RS17785	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AN947_RS17800	COG0187	DNA topoisomerase II activity
AN947_RS17805	COG3150	esterase
AN947_RS17815	COG3151	Protein conserved in bacteria
AN947_RS17820	COG0494	nUDIX hydrolase
AN947_RS17825	COG1538	Outer membrane efflux protein
AN947_RS17835	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AN947_RS17840	COG0840	transmembrane signaling receptor activity
AN947_RS17845	COG3025	triphosphatase activity
AN947_RS17850	COG1392	Phosphate transport regulator
AN947_RS17855	COG0306	phosphate transporter
AN947_RS17860	COG4991	sh3 domain protein
AN947_RS17870	COG3409	Peptidoglycan-binding domain 1 protein
AN947_RS17870	COG3267	Type II secretory pathway component ExeA
AN947_RS17880	COG0148	phosphopyruvate hydratase activity
AN947_RS17885	COG0504	CTP synthase activity
AN947_RS17890	COG3956	TIGRFAM MazG family protein
AN947_RS17895	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AN947_RS17910	COG5001	Diguanylate cyclase
AN947_RS17930	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AN947_RS17935	COG1381	Involved in DNA repair and RecF pathway recombination
AN947_RS17940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AN947_RS17955	COG0481	GTPase activity
AN947_RS17960	COG3086	response to oxidative stress
AN947_RS17975	COG1595	DNA-templated transcription, initiation
AN947_RS17985	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AN947_RS17995	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AN947_RS18010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN947_RS18015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN947_RS18020	COG3079	Belongs to the UPF0149 family
AN947_RS18025	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AN947_RS18035	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AN947_RS18040	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AN947_RS18045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AN947_RS18050	COG0440	acetolactate synthase activity
AN947_RS18055	COG0028	Belongs to the TPP enzyme family
AN947_RS18060	COG1022	Amp-dependent synthetase and ligase
AN947_RS18065	COG0583	DNA-binding transcription factor activity
AN947_RS18090	COG0473	3-isopropylmalate dehydrogenase activity
AN947_RS18095	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AN947_RS18100	COG0066	3-isopropylmalate dehydratase activity
AN947_RS18145	COG3437	response regulator, receiver
AN947_RS18160	COG0795	lipopolysaccharide-transporting ATPase activity
AN947_RS18165	COG0795	lipopolysaccharide-transporting ATPase activity
AN947_RS18170	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AN947_RS18175	COG2927	DNA polymerase III (CHI subunit)
AN947_RS18180	COG0525	valine-tRNA ligase activity
AN947_RS18185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AN947_RS18190	COG0564	pseudouridine synthase activity
AN947_RS18205	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AN947_RS18215	COG0540	Belongs to the ATCase OTCase family
AN947_RS18225	COG0251	oxidation-reduction process
AN947_RS18235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AN947_RS18240	COG5007	Belongs to the BolA IbaG family
AN947_RS18250	COG2854	intermembrane phospholipid transfer
AN947_RS18255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AN947_RS18260	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AN947_RS18265	COG1127	ABC transporter
AN947_RS18280	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AN947_RS18280	COG0517	IMP dehydrogenase activity
AN947_RS18295	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AN947_RS18300	COG1137	ATPase activity
AN947_RS18310	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AN947_RS18315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN947_RS18320	COG1660	Displays ATPase and GTPase activities
AN947_RS18325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN947_RS18330	COG2239	Acts as a magnesium transporter
AN947_RS18335	COG0312	modulator of DNA gyrase
AN947_RS18340	COG3028	Belongs to the UPF0307 family
AN947_RS18345	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AN947_RS18350	COG1178	ABC-type Fe3 transport system permease component
AN947_RS18360	COG0163	prenyltransferase activity
AN947_RS18365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AN947_RS18380	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AN947_RS18385	COG2105	PFAM AIG2 family protein
AN947_RS18395	COG0729	surface antigen
AN947_RS18400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AN947_RS18405	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AN947_RS18420	COG1136	(ABC) transporter
AN947_RS18440	COG0529	Catalyzes the synthesis of activated sulfate
AN947_RS18455	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AN947_RS18455	COG1648	precorrin-2 dehydrogenase activity
AN947_RS18460	COG0737	Belongs to the 5'-nucleotidase family
AN947_RS18470	COG0513	Belongs to the DEAD box helicase family
AN947_RS18475	COG2153	protein acetylation
AN947_RS18480	COG0697	spore germination
AN947_RS18485	COG3266	domain, Protein
AN947_RS18485	COG3061	Opacity-associated protein A
AN947_RS18490	COG0545	Peptidyl-prolyl cis-trans isomerase
AN947_RS18505	COG0202	RNA polymerase activity
AN947_RS18510	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AN947_RS18520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AN947_RS18525	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AN947_RS18530	COG0201	protein transport
AN947_RS18540	COG1841	ribosomal large subunit assembly
AN947_RS18545	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AN947_RS18550	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AN947_RS18560	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AN947_RS18565	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AN947_RS18570	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AN947_RS18575	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AN947_RS18580	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AN947_RS18585	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AN947_RS18590	COG0255	Belongs to the universal ribosomal protein uL29 family
AN947_RS18595	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AN947_RS18600	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AN947_RS18605	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AN947_RS18610	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AN947_RS18615	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AN947_RS18620	COG0089	rRNA binding
AN947_RS18625	COG0088	Forms part of the polypeptide exit tunnel
AN947_RS18630	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AN947_RS18635	COG0051	transcription antitermination factor activity, RNA binding
AN947_RS18640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN947_RS18645	COG0557	exoribonuclease II activity
AN947_RS18650	COG3083	sulfuric ester hydrolase activity
AN947_RS18655	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AN947_RS18675	COG1047	Peptidyl-prolyl cis-trans
AN947_RS18690	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN947_RS18695	COG0488	(ABC) transporter
AN947_RS18705	COG0429	hydrolase of the alpha beta-hydrolase fold
AN947_RS18715	COG3954	Phosphoribulokinase
AN947_RS18730	COG1012	belongs to the aldehyde dehydrogenase family
AN947_RS18740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AN947_RS18750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AN947_RS18765	COG0180	Tryptophanyl-tRNA synthetase
AN947_RS18770	COG0546	phosphoglycolate phosphatase activity
AN947_RS18775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AN947_RS18780	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AN947_RS18795	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AN947_RS18825	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AN947_RS18835	COG0678	peroxiredoxin activity
AN947_RS18835	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AN947_RS18840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN947_RS18850	COG0165	Argininosuccinate lyase
AN947_RS18860	COG0137	argininosuccinate synthase activity
AN947_RS18865	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AN947_RS18870	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AN947_RS18875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AN947_RS18880	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AN947_RS18890	COG1045	serine acetyltransferase
AN947_RS18895	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AN947_RS18900	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AN947_RS18905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN947_RS18910	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AN947_RS18915	COG1053	succinate dehydrogenase
AN947_RS18920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AN947_RS18925	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AN947_RS18935	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AN947_RS18950	COG0459	protein refolding
AN947_RS18955	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AN947_RS18990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AN947_RS18995	COG1575	Belongs to the MenA family. Type 1 subfamily
AN947_RS19000	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AN947_RS19005	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AN947_RS19010	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AN947_RS19015	COG1609	Transcriptional regulator
AN947_RS19020	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AN947_RS19025	COG0254	rRNA binding
AN947_RS19030	COG0281	malic enzyme
AN947_RS19035	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AN947_RS19040	COG0626	cystathionine gamma-synthase activity
AN947_RS19045	COG0460	homoserine dehydrogenase
AN947_RS19045	COG0527	aspartate kinase activity
AN947_RS19050	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AN947_RS19055	COG3074	FtsZ-dependent cytokinesis
AN947_RS19060	COG1494	fructose-1,6-bisphosphatase
AN947_RS19065	COG0205	6-phosphofructokinase activity
AN947_RS19070	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AN947_RS19080	COG0745	RESPONSE REGULATOR receiver
AN947_RS19085	COG2205	protein histidine kinase activity
AN947_RS19095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AN947_RS19100	COG3030	protein affecting phage T7 exclusion by the F plasmid
AN947_RS19105	COG3706	GGDEF domain
AN947_RS19110	COG1027	Aspartate ammonia-lyase
AN947_RS19115	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AN947_RS19125	COG4232	protein-disulfide reductase activity
AN947_RS19145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN947_RS19150	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AN947_RS19155	COG0194	GDP metabolic process
AN947_RS19160	COG1758	RNA polymerase activity
AN947_RS19165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AN947_RS19170	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AN947_RS19175	COG2233	PERMEase
AN947_RS19190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AN947_RS19195	COG2183	response to ionizing radiation
AN947_RS19205	COG0596	Alpha beta hydrolase
AN947_RS19210	COG1040	competence protein
AN947_RS19220	COG0494	nUDIX hydrolase
AN947_RS19225	COG1218	3'(2'),5'-bisphosphate nucleotidase
AN947_RS19240	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AN947_RS19245	COG3156	type II secretion system protein K
AN947_RS19250	COG4795	General secretion pathway protein
AN947_RS19255	COG2165	general secretion pathway protein
AN947_RS19260	COG2165	general secretion pathway protein
AN947_RS19265	COG2165	general secretion pathway protein
AN947_RS19270	COG1459	type II secretion system
AN947_RS19275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AN947_RS19285	COG3031	protein transport across the cell outer membrane
AN947_RS19290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AN947_RS19295	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AN947_RS19300	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AN947_RS19310	COG0456	acetyltransferase
AN947_RS19315	COG1490	D-aminoacyl-tRNA deacylase activity
AN947_RS19320	COG1295	ribonuclease BN
AN947_RS19325	COG1660	Displays ATPase and GTPase activities
AN947_RS19330	COG1217	gtp-binding protein TYPA
AN947_RS19340	COG0174	glutamine synthetase
AN947_RS19350	COG3852	Histidine kinase
AN947_RS19360	COG3300	MHYT domain
AN947_RS19360	COG5001	Diguanylate cyclase
AN947_RS19365	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AN947_RS19445	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AN947_RS19450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AN947_RS19455	COG1739	Uncharacterized protein family UPF0029
AN947_RS19470	COG0583	DNA-binding transcription factor activity
AN947_RS19475	COG2814	Major facilitator Superfamily
AN947_RS19480	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AN947_RS19485	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AN947_RS19490	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AN947_RS19495	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AN947_RS19500	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AN947_RS19505	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AN947_RS19510	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AN947_RS19520	COG0356	it plays a direct role in the translocation of protons across the membrane
AN947_RS19525	COG3312	ion transport
AN947_RS19530	COG1475	DNA binding
AN947_RS19535	COG1192	Involved in chromosome partitioning
AN947_RS19545	COG0445	tRNA wobble uridine modification
AN947_RS19595	COG1660	Displays ATPase and GTPase activities
AN947_RS19680	COG0488	(ABC) transporter
AN947_RS19685	COG3173	Aminoglycoside phosphotransferase
AN947_RS19830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AN947_RS19850	COG1192	Involved in chromosome partitioning
AN947_RS19940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AN947_RS20030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN947_RS20055	COG5001	Diguanylate cyclase
AN947_RS20090	COG0714	Associated with various cellular activities
AN947_RS20100	COG0629	single-stranded DNA binding
AN947_RS20145	COG0633	Ferredoxin
AN947_RS20325	COG4974	Belongs to the 'phage' integrase family
AN947_RS20500	COG0616	signal peptide processing
AN947_RS20620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AN947_RS20685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol