locus-tag	class	description
VCLMA_RS00010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCLMA_RS00015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
VCLMA_RS00020	COG0706	membrane insertase activity
VCLMA_RS00030	COG0594	ribonuclease P activity
VCLMA_RS00035	COG0230	Belongs to the bacterial ribosomal protein bL34 family
VCLMA_RS00040	COG1126	abc transporter atp-binding protein
VCLMA_RS00055	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VCLMA_RS00060	COG0592	DNA-directed DNA polymerase activity
VCLMA_RS00065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
VCLMA_RS00085	COG0071	Belongs to the small heat shock protein (HSP20) family
VCLMA_RS00090	COG3977	Valine--pyruvate aminotransferase
VCLMA_RS00095	COG0751	glycine-tRNA ligase activity
VCLMA_RS00100	COG0752	glycyl-tRNA synthetase alpha subunit
VCLMA_RS00105	COG2119	membrane
VCLMA_RS00115	COG0425	Belongs to the sulfur carrier protein TusA family
VCLMA_RS00125	COG0604	alcohol dehydrogenase
VCLMA_RS00135	COG0129	dihydroxy-acid dehydratase activity
VCLMA_RS00140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCLMA_RS00160	COG0204	Acyl-transferase
VCLMA_RS00165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCLMA_RS00170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VCLMA_RS00180	COG3084	Protein conserved in bacteria
VCLMA_RS00190	COG4326	sporulation control protein
VCLMA_RS00195	COG1272	protein, Hemolysin III
VCLMA_RS00205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCLMA_RS00210	COG0569	domain protein
VCLMA_RS00215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCLMA_RS00215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
VCLMA_RS00220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
VCLMA_RS00225	COG0242	peptide deformylase activity
VCLMA_RS00230	COG1652	LysM domain
VCLMA_RS00235	COG0758	DNA mediated transformation
VCLMA_RS00240	COG2922	Belongs to the Smg family
VCLMA_RS00245	COG0551	DNA topoisomerase type I activity
VCLMA_RS00250	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
VCLMA_RS00255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
VCLMA_RS00260	COG0009	L-threonylcarbamoyladenylate synthase
VCLMA_RS00265	COG0408	coproporphyrinogen oxidase activity
VCLMA_RS00270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
VCLMA_RS00280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
VCLMA_RS00315	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
VCLMA_RS00320	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VCLMA_RS00330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
VCLMA_RS00335	COG2104	thiamine diphosphate biosynthetic process
VCLMA_RS00340	COG2022	thiamine diphosphate biosynthetic process
VCLMA_RS00345	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCLMA_RS00350	COG0006	proline dipeptidase activity
VCLMA_RS00350	COG0006	proline dipeptidase activity
VCLMA_RS00370	COG1522	sequence-specific DNA binding
VCLMA_RS00375	COG5002	protein histidine kinase activity
VCLMA_RS00375	COG5001	Diguanylate cyclase
VCLMA_RS00395	COG0589	response to stress
VCLMA_RS00405	COG1528	Iron-storage protein
VCLMA_RS00415	COG2081	HI0933 family
VCLMA_RS00425	COG1322	Protein conserved in bacteria
VCLMA_RS00430	COG2226	methyltransferase
VCLMA_RS00445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCLMA_RS00450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
VCLMA_RS00455	COG0805	protein transport
VCLMA_RS00460	COG1858	cytochrome C peroxidase
VCLMA_RS00465	COG0534	Mate efflux family protein
VCLMA_RS00475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
VCLMA_RS00480	COG2937	Belongs to the GPAT DAPAT family
VCLMA_RS00485	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
VCLMA_RS00490	COG3161	chorismate lyase activity
VCLMA_RS00500	COG1580	Controls the rotational direction of flagella during chemotaxis
VCLMA_RS00505	COG0840	transmembrane signaling receptor activity
VCLMA_RS00515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCLMA_RS00525	COG0084	hydrolase, TatD family'
VCLMA_RS00545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCLMA_RS00545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCLMA_RS00565	COG3078	GTPase activator activity
VCLMA_RS00580	COG3071	HemY protein
VCLMA_RS00585	COG2959	enzyme of heme biosynthesis
VCLMA_RS00590	COG1587	Uroporphyrinogen-III synthase
VCLMA_RS00595	COG0181	hydroxymethylbilane synthase activity
VCLMA_RS00610	COG1965	Belongs to the frataxin family
VCLMA_RS00620	COG0019	diaminopimelate decarboxylase activity
VCLMA_RS00625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
VCLMA_RS00635	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
VCLMA_RS00640	COG1011	Hydrolase
VCLMA_RS00645	COG3287	FIST C domain
VCLMA_RS00645	COG2200	EAL domain
VCLMA_RS00645	COG2199	diguanylate cyclase activity
VCLMA_RS00665	COG0561	phosphatase activity
VCLMA_RS00670	COG2267	carboxylic ester hydrolase activity
VCLMA_RS00675	COG1280	lysine exporter protein (LysE YggA)
VCLMA_RS00680	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCLMA_RS00685	COG0783	Belongs to the Dps family
VCLMA_RS00720	COG0742	ribosomal rna small subunit methyltransferase
VCLMA_RS00725	COG0552	protein localization to endoplasmic reticulum
VCLMA_RS00730	COG2884	Cell division ATP-binding protein ftsE
VCLMA_RS00735	COG2177	Part of the ABC transporter FtsEX involved in
VCLMA_RS00740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCLMA_RS00745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCLMA_RS00760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
VCLMA_RS00765	COG1404	Belongs to the peptidase S8 family
VCLMA_RS00770	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
VCLMA_RS00805	COG0583	DNA-binding transcription factor activity
VCLMA_RS00810	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
VCLMA_RS00815	COG2960	long-chain fatty acid transporting porin activity
VCLMA_RS00820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
VCLMA_RS00825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCLMA_RS00830	COG1309	transcriptional regulator
VCLMA_RS00880	COG0747	negative chemotaxis
VCLMA_RS00885	COG0601	transmembrane transport
VCLMA_RS00890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCLMA_RS00900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCLMA_RS00905	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
VCLMA_RS00915	COG0210	DNA helicase
VCLMA_RS00920	COG1280	lysine exporter protein (LysE YggA)
VCLMA_RS00930	COG0405	Gamma-glutamyltransferase
VCLMA_RS00935	COG2962	Rard protein
VCLMA_RS00940	COG0514	ATP-dependent DNA helicase (RecQ)
VCLMA_RS00960	COG4774	siderophore transport
VCLMA_RS00965	COG1120	ATPase activity
VCLMA_RS00990	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCLMA_RS00995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCLMA_RS00995	COG1263	PTS System
VCLMA_RS01000	COG2862	Uncharacterized protein family, UPF0114
VCLMA_RS01005	COG1561	YicC-like family, N-terminal region
VCLMA_RS01010	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
VCLMA_RS01015	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
VCLMA_RS01020	COG1560	Kdo2-lipid A biosynthetic process
VCLMA_RS01030	COG1309	transcriptional regulator
VCLMA_RS01035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
VCLMA_RS01045	COG2003	Belongs to the UPF0758 family
VCLMA_RS01050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
VCLMA_RS01055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
VCLMA_RS01065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
VCLMA_RS01070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
VCLMA_RS01075	COG0859	PFAM glycosyl transferase family 9
VCLMA_RS01080	COG0463	Glycosyl transferase, family 2
VCLMA_RS01085	COG0859	PFAM glycosyl transferase family 9
VCLMA_RS01090	COG3642	lipopolysaccharide core region biosynthetic process
VCLMA_RS01120	COG1519	Transferase
VCLMA_RS01155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCLMA_RS01160	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
VCLMA_RS01160	COG0662	Cupin 2, conserved barrel domain protein
VCLMA_RS01165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
VCLMA_RS01170	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
VCLMA_RS01200	COG0318	PFAM AMP-dependent synthetase and ligase
VCLMA_RS01205	COG1012	belongs to the aldehyde dehydrogenase family
VCLMA_RS01205	COG1454	alcohol dehydrogenase
VCLMA_RS01220	COG5433	transposase activity
VCLMA_RS01270	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
VCLMA_RS01275	COG0668	transmembrane transport
VCLMA_RS01280	COG1573	uracil-dna glycosylase
VCLMA_RS01290	COG3068	Protein conserved in bacteria
VCLMA_RS01300	COG1940	carbohydrate kinase activity
VCLMA_RS01305	COG1253	flavin adenine dinucleotide binding
VCLMA_RS01315	COG0776	regulation of translation
VCLMA_RS01325	COG0151	Belongs to the GarS family
VCLMA_RS01335	COG0789	Transcriptional regulator
VCLMA_RS01340	COG3710	Transcriptional regulator
VCLMA_RS01345	COG0531	amino acid
VCLMA_RS01350	COG1982	Orn Lys Arg decarboxylase major
VCLMA_RS01355	COG0840	transmembrane signaling receptor activity
VCLMA_RS01370	COG0800	Aldolase
VCLMA_RS01375	COG2610	gluconate transmembrane transporter activity
VCLMA_RS01380	COG3265	gluconokinase activity
VCLMA_RS01385	COG0129	dihydroxy-acid dehydratase activity
VCLMA_RS01390	COG1609	Transcriptional regulator
VCLMA_RS01395	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
VCLMA_RS01400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCLMA_RS01405	COG2264	protein methyltransferase activity
VCLMA_RS01410	COG0439	Biotin carboxylase
VCLMA_RS01415	COG0511	ligase activity, forming carbon-carbon bonds
VCLMA_RS01420	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
VCLMA_RS01425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
VCLMA_RS01445	COG2814	Major facilitator Superfamily
VCLMA_RS01450	COG2205	protein histidine kinase activity
VCLMA_RS01450	COG0784	Response regulator, receiver
VCLMA_RS01455	COG0248	Ppx GppA phosphatase
VCLMA_RS01460	COG0513	Belongs to the DEAD box helicase family
VCLMA_RS01465	COG3118	belongs to the thioredoxin family
VCLMA_RS01480	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
VCLMA_RS01525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
VCLMA_RS01540	COG0812	UDP-N-acetylmuramate dehydrogenase activity
VCLMA_RS01550	COG1072	(Pantothenic acid kinase))
VCLMA_RS01575	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCLMA_RS01580	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCLMA_RS01585	COG0250	Participates in transcription elongation, termination and antitermination
VCLMA_RS01590	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
VCLMA_RS01600	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
VCLMA_RS01620	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
VCLMA_RS01625	COG2816	NAD+ diphosphatase activity
VCLMA_RS01630	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
VCLMA_RS01645	COG4942	peptidase
VCLMA_RS01650	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
VCLMA_RS01660	COG0471	metal ion transport
VCLMA_RS01665	COG0688	phosphatidylethanolamine metabolic process
VCLMA_RS01670	COG1162	GTPase activity
VCLMA_RS01715	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
VCLMA_RS01720	COG0802	atpase or kinase
VCLMA_RS01735	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
VCLMA_RS01740	COG1923	regulation of RNA biosynthetic process
VCLMA_RS01745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
VCLMA_RS01755	COG0330	HflC and HflK could
VCLMA_RS01760	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
VCLMA_RS01765	COG2900	Belongs to the SlyX family
VCLMA_RS01780	COG2964	Protein conserved in bacteria
VCLMA_RS01790	COG2923	Belongs to the DsrF TusC family
VCLMA_RS01805	COG0049	tRNA binding
VCLMA_RS01810	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCLMA_RS01820	COG2906	2 iron, 2 sulfur cluster binding
VCLMA_RS01835	COG2965	DNA replication, synthesis of RNA primer
VCLMA_RS01840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
VCLMA_RS01845	COG0359	binds to the 23S rRNA
VCLMA_RS01860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
VCLMA_RS01870	COG0432	Pfam Uncharacterised protein family UPF0047
VCLMA_RS01875	COG0166	Belongs to the GPI family
VCLMA_RS01890	COG0735	belongs to the Fur family
VCLMA_RS01895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCLMA_RS01920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
VCLMA_RS01930	COG0175	sulfate reduction
VCLMA_RS01970	COG0646	methionine synthase
VCLMA_RS01970	COG1410	methionine synthase
VCLMA_RS01975	COG0527	aspartate kinase activity
VCLMA_RS01980	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
VCLMA_RS01990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
VCLMA_RS02005	COG0629	single-stranded DNA binding
VCLMA_RS02035	COG3409	Peptidoglycan-binding domain 1 protein
VCLMA_RS02035	COG3267	Type II secretory pathway component ExeA
VCLMA_RS02045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCLMA_RS02050	COG1459	type II secretion system
VCLMA_RS02060	COG2165	general secretion pathway protein
VCLMA_RS02065	COG2165	general secretion pathway protein
VCLMA_RS02095	COG1077	Cell shape determining protein MreB Mrl
VCLMA_RS02100	COG1792	Involved in formation and maintenance of cell shape
VCLMA_RS02105	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
VCLMA_RS02110	COG0424	maF-like protein
VCLMA_RS02120	COG3164	Protein of unknown function
VCLMA_RS02125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
VCLMA_RS02135	COG2235	arginine
VCLMA_RS02155	COG0589	response to stress
VCLMA_RS02165	COG2358	TRAP transporter, solute receptor (TAXI family
VCLMA_RS02170	COG1438	arginine binding
VCLMA_RS02175	COG0039	L-malate dehydrogenase activity
VCLMA_RS02180	COG0531	amino acid
VCLMA_RS02185	COG0142	geranyltranstransferase activity
VCLMA_RS02190	COG0261	This protein binds to 23S rRNA in the presence of protein L20
VCLMA_RS02195	COG0211	Belongs to the bacterial ribosomal protein bL27 family
VCLMA_RS02200	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VCLMA_RS02205	COG2966	Psort location CytoplasmicMembrane, score
VCLMA_RS02210	COG3610	response to peptide
VCLMA_RS02220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
VCLMA_RS02225	COG2967	ApaG domain
VCLMA_RS02230	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
VCLMA_RS02235	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
VCLMA_RS02250	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
VCLMA_RS02275	COG0741	lytic transglycosylase activity
VCLMA_RS02280	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
VCLMA_RS02285	COG1194	a g-specific adenine glycosylase
VCLMA_RS02290	COG0220	tRNA (guanine-N7-)-methyltransferase activity
VCLMA_RS02295	COG2066	Belongs to the glutaminase family
VCLMA_RS02300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
VCLMA_RS02305	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
VCLMA_RS02315	COG1872	DUF167
VCLMA_RS02320	COG0762	integral membrane protein
VCLMA_RS02325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
VCLMA_RS02330	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
VCLMA_RS02350	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCLMA_RS02355	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
VCLMA_RS02360	COG1678	Uncharacterized ACR, COG1678
VCLMA_RS02365	COG0189	ligase activity
VCLMA_RS02370	COG1385	rRNA (uridine-N3-)-methyltransferase activity
VCLMA_RS02375	COG2356	endonuclease I
VCLMA_RS02380	COG3091	SprT-like family
VCLMA_RS02385	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
VCLMA_RS02400	COG0583	DNA-binding transcription factor activity
VCLMA_RS02410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCLMA_RS02415	COG0126	phosphoglycerate kinase activity
VCLMA_RS02420	COG0191	fructose-bisphosphate aldolase activity
VCLMA_RS02430	COG0668	transmembrane transport
VCLMA_RS02435	COG1279	arginine transmembrane transporter activity
VCLMA_RS02460	COG1349	DNA-binding transcription factor activity
VCLMA_RS02465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
VCLMA_RS02470	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
VCLMA_RS02500	COG1610	YqeY-like protein
VCLMA_RS02505	COG0828	Belongs to the bacterial ribosomal protein bS21 family
VCLMA_RS02520	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
VCLMA_RS02525	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
VCLMA_RS02530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCLMA_RS02535	COG1968	undecaprenyl-diphosphatase activity
VCLMA_RS02540	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
VCLMA_RS02545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
VCLMA_RS02550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
VCLMA_RS02555	COG0585	pseudouridine synthase activity
VCLMA_RS02560	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
VCLMA_RS02565	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
VCLMA_RS02575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
VCLMA_RS02580	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
VCLMA_RS02600	COG4208	sulfate ABC transporter
VCLMA_RS02615	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
VCLMA_RS02620	COG2137	regulation of response to DNA damage stimulus
VCLMA_RS02625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
VCLMA_RS02630	COG0527	aspartate kinase activity
VCLMA_RS02635	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
VCLMA_RS02690	COG3630	sodium ion export across plasma membrane
VCLMA_RS02700	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCLMA_RS02710	COG1238	metal cluster binding
VCLMA_RS02715	COG0612	Peptidase, M16
VCLMA_RS02720	COG2918	glutathione biosynthetic process
VCLMA_RS02725	COG1854	S-ribosylhomocysteine lyase activity
VCLMA_RS02730	COG4536	flavin adenine dinucleotide binding
VCLMA_RS02740	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VCLMA_RS02745	COG0228	four-way junction DNA binding
VCLMA_RS02755	COG0336	Belongs to the RNA methyltransferase TrmD family
VCLMA_RS02760	COG0335	large ribosomal subunit rRNA binding
VCLMA_RS02765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
VCLMA_RS02780	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
VCLMA_RS02790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
VCLMA_RS02795	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
VCLMA_RS02800	COG0723	plastoquinol--plastocyanin reductase activity
VCLMA_RS02805	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
VCLMA_RS02815	COG0625	glutathione transferase activity
VCLMA_RS02820	COG2969	positive regulation of protein catabolic process
VCLMA_RS02825	COG2823	Periplasmic or secreted lipoprotein
VCLMA_RS02830	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCLMA_RS02835	COG0792	nuclease activity
VCLMA_RS02840	COG3107	peptidoglycan biosynthetic process
VCLMA_RS02845	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
VCLMA_RS02860	COG0288	reversible hydration of carbon dioxide
VCLMA_RS02870	COG1131	(ABC) transporter
VCLMA_RS02875	COG0842	Transport permease protein
VCLMA_RS02880	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
VCLMA_RS02885	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VCLMA_RS02890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCLMA_RS02900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCLMA_RS02910	COG1489	DNA binding
VCLMA_RS02920	COG1643	Atp-dependent helicase
VCLMA_RS02925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
VCLMA_RS02930	COG1752	Esterase of the alpha-beta hydrolase superfamily
VCLMA_RS02935	COG1049	propionate catabolic process, 2-methylcitrate cycle
VCLMA_RS02940	COG3112	Uncharacterised protein family (UPF0231)
VCLMA_RS02945	COG0347	Belongs to the P(II) protein family
VCLMA_RS02950	COG0004	ammonium transporteR
VCLMA_RS02955	COG1840	ABC-type Fe3 transport system, periplasmic component
VCLMA_RS02965	COG3842	ATPase activity
VCLMA_RS02985	COG2971	BadF BadG BcrA BcrD
VCLMA_RS02995	COG4608	Belongs to the ABC transporter superfamily
VCLMA_RS03000	COG0444	Belongs to the ABC transporter superfamily
VCLMA_RS03005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCLMA_RS03030	COG2813	Specifically methylates the guanine in position
VCLMA_RS03035	COG0628	permease
VCLMA_RS03045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
VCLMA_RS03050	COG0316	Belongs to the HesB IscA family
VCLMA_RS03065	COG0739	heme binding
VCLMA_RS03070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
VCLMA_RS03075	COG2027	D-alanyl-D-alanine carboxypeptidase
VCLMA_RS03085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCLMA_RS03090	COG1534	Rna-binding protein
VCLMA_RS03095	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
VCLMA_RS03100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
VCLMA_RS03105	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
VCLMA_RS03115	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
VCLMA_RS03130	COG0779	Required for maturation of 30S ribosomal subunits
VCLMA_RS03135	COG0195	Participates in both transcription termination and antitermination
VCLMA_RS03145	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
VCLMA_RS03155	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
VCLMA_RS03180	COG0826	peptidase U32
VCLMA_RS03185	COG0826	peptidase U32
VCLMA_RS03195	COG3154	lipid carrier protein
VCLMA_RS03200	COG3153	acetyltransferase
VCLMA_RS03225	COG0513	Belongs to the DEAD box helicase family
VCLMA_RS03240	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
VCLMA_RS03245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
VCLMA_RS03250	COG2204	response regulator
VCLMA_RS03260	COG0667	Aldo Keto reductase
VCLMA_RS03265	COG3066	DNA modification
VCLMA_RS03270	COG0494	nUDIX hydrolase
VCLMA_RS03275	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
VCLMA_RS03280	COG0730	response to heat
VCLMA_RS03285	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
VCLMA_RS03295	COG1283	sodium-dependent phosphate transmembrane transporter activity
VCLMA_RS03300	COG0583	DNA-binding transcription factor activity
VCLMA_RS03305	COG0640	Transcriptional regulator
VCLMA_RS03310	COG0268	Binds directly to 16S ribosomal RNA
VCLMA_RS03315	COG0728	peptidoglycan biosynthetic process
VCLMA_RS03320	COG0196	riboflavin kinase activity
VCLMA_RS03330	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
VCLMA_RS03335	COG1047	Peptidyl-prolyl cis-trans
VCLMA_RS03340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
VCLMA_RS03345	COG1966	Carbon starvation protein
VCLMA_RS03355	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VCLMA_RS03360	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
VCLMA_RS03370	COG3279	Response regulator of the LytR AlgR family
VCLMA_RS03375	COG3275	phosphorelay sensor kinase activity
VCLMA_RS03380	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCLMA_RS03385	COG0287	Prephenate dehydrogenase
VCLMA_RS03385	COG1605	Chorismate mutase
VCLMA_RS03395	COG0488	(ABC) transporter
VCLMA_RS03405	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
VCLMA_RS03415	COG5001	Diguanylate cyclase
VCLMA_RS03420	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
VCLMA_RS03425	COG0077	Prephenate dehydratase
VCLMA_RS03425	COG1605	Chorismate mutase
VCLMA_RS03430	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCLMA_RS03435	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCLMA_RS03440	COG0564	pseudouridine synthase activity
VCLMA_RS03445	COG1496	oxidoreductase activity
VCLMA_RS03490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
VCLMA_RS03495	COG0826	peptidase U32
VCLMA_RS03505	COG0745	RESPONSE REGULATOR receiver
VCLMA_RS03510	COG5002	protein histidine kinase activity
VCLMA_RS03520	COG0248	Ppx GppA phosphatase
VCLMA_RS03525	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
VCLMA_RS03535	COG0581	inorganic phosphate transmembrane transporter activity
VCLMA_RS03540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
VCLMA_RS03555	COG3142	Participates in the control of copper homeostasis
VCLMA_RS03560	COG0450	alkyl hydroperoxide reductase
VCLMA_RS03565	COG0583	DNA-binding transcription factor activity
VCLMA_RS03585	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
VCLMA_RS03600	COG1862	Preprotein translocase
VCLMA_RS03605	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCLMA_RS03610	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
VCLMA_RS03615	COG0483	inositol monophosphate 1-phosphatase activity
VCLMA_RS03635	COG0822	iron-sulfur transferase activity
VCLMA_RS03655	COG0633	Ferredoxin
VCLMA_RS03660	COG2975	iron-sulfur cluster assembly
VCLMA_RS03665	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCLMA_RS03670	COG0105	UTP biosynthetic process
VCLMA_RS03685	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
VCLMA_RS03695	COG2976	Protein conserved in bacteria
VCLMA_RS03700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCLMA_RS03705	COG1160	GTP binding
VCLMA_RS03720	COG1570	exodeoxyribonuclease VII activity
VCLMA_RS03725	COG0516	GMP reductase activity
VCLMA_RS03725	COG0517	IMP dehydrogenase activity
VCLMA_RS03730	COG0519	Catalyzes the synthesis of GMP from XMP
VCLMA_RS03730	COG0518	GMP synthase (glutamine-hydrolyzing) activity
VCLMA_RS03740	COG1584	GPR1 FUN34 yaaH family protein
VCLMA_RS03745	COG1535	isochorismatase
VCLMA_RS03745	COG3433	isochorismatase activity
VCLMA_RS03750	COG1021	2,3-dihydroxybenzoate-AMP ligase
VCLMA_RS03755	COG1169	isochorismate synthase
VCLMA_RS03760	COG1028	Short-chain dehydrogenase reductase Sdr
VCLMA_RS03770	COG4592	Periplasmic binding protein
VCLMA_RS03775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCLMA_RS03780	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCLMA_RS03785	COG1120	ATPase activity
VCLMA_RS03790	COG2977	Belongs to the P-Pant transferase superfamily
VCLMA_RS03795	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
VCLMA_RS03800	COG1120	ATPase activity
VCLMA_RS03810	COG1115	amino acid carrier protein
VCLMA_RS03820	COG0583	DNA-binding transcription factor activity
VCLMA_RS03835	COG4565	transcriptional regulatory protein
VCLMA_RS03845	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
VCLMA_RS03850	COG5016	pyruvate
VCLMA_RS03850	COG0511	ligase activity, forming carbon-carbon bonds
VCLMA_RS03855	COG3630	sodium ion export across plasma membrane
VCLMA_RS03880	COG3051	citrate lyase alpha subunit
VCLMA_RS03900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCLMA_RS03905	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
VCLMA_RS03910	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
VCLMA_RS03965	COG0582	viral genome integration into host DNA
VCLMA_RS03970	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
VCLMA_RS03975	COG2867	negative regulation of translational initiation
VCLMA_RS03980	COG2914	Belongs to the UPF0125 (RnfH) family
VCLMA_RS03985	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VCLMA_RS03995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
VCLMA_RS04000	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VCLMA_RS04005	COG0443	Heat shock 70 kDa protein
VCLMA_RS04010	COG0484	heat shock protein binding
VCLMA_RS04045	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCLMA_RS04060	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
VCLMA_RS04070	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VCLMA_RS04070	COG0047	phosphoribosylformylglycinamidine synthase activity
VCLMA_RS04100	COG0442	prolyl-tRNA aminoacylation
VCLMA_RS04105	COG1720	tRNA m6t6A37 methyltransferase activity
VCLMA_RS04110	COG0254	rRNA binding
VCLMA_RS04115	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCLMA_RS04125	COG1671	Belongs to the UPF0178 family
VCLMA_RS04135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCLMA_RS04150	COG3098	single-species biofilm formation
VCLMA_RS04155	COG0564	pseudouridine synthase activity
VCLMA_RS04160	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
VCLMA_RS04165	COG0142	geranyltranstransferase activity
VCLMA_RS04175	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
VCLMA_RS04185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCLMA_RS04185	COG0301	tRNA thio-modification
VCLMA_RS04195	COG0583	DNA-binding transcription factor activity
VCLMA_RS04200	COG2363	Small membrane protein
VCLMA_RS04205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
VCLMA_RS04210	COG1611	Belongs to the LOG family
VCLMA_RS04225	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCLMA_RS04225	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
VCLMA_RS04235	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
VCLMA_RS04240	COG1464	Belongs to the NlpA lipoprotein family
VCLMA_RS04245	COG2011	ABC-type metal ion transport system permease component
VCLMA_RS04250	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
VCLMA_RS04255	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCLMA_RS04260	COG1609	Transcriptional regulator
VCLMA_RS04265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCLMA_RS04265	COG1263	PTS System
VCLMA_RS04270	COG0366	Alpha amylase catalytic
VCLMA_RS04305	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
VCLMA_RS04310	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
VCLMA_RS04330	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
VCLMA_RS04360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
VCLMA_RS04370	COG1596	polysaccharide export
VCLMA_RS04395	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
VCLMA_RS04405	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
VCLMA_RS04410	COG0321	lipoyl(octanoyl) transferase activity
VCLMA_RS04415	COG2921	Belongs to the UPF0250 family
VCLMA_RS04425	COG1686	Belongs to the peptidase S11 family
VCLMA_RS04430	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
VCLMA_RS04435	COG0772	Belongs to the SEDS family
VCLMA_RS04440	COG0768	penicillin binding
VCLMA_RS04445	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
VCLMA_RS04450	COG0799	negative regulation of ribosome biogenesis
VCLMA_RS04455	COG1466	dna polymerase III delta subunit
VCLMA_RS04460	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
VCLMA_RS04465	COG0495	leucyl-tRNA aminoacylation
VCLMA_RS04470	COG2888	peptidyl-tyrosine sulfation
VCLMA_RS04480	COG4535	Mg2 and Co2 transporter CorC
VCLMA_RS04485	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
VCLMA_RS04495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCLMA_RS04500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCLMA_RS04505	COG2190	(PTS) system
VCLMA_RS04515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCLMA_RS04525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
VCLMA_RS04530	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
VCLMA_RS04535	COG3115	cell septum assembly
VCLMA_RS04540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
VCLMA_RS04555	COG0789	Transcriptional regulator
VCLMA_RS04560	COG1585	Membrane protein implicated in regulation of membrane protease activity
VCLMA_RS04565	COG0330	HflC and HflK could
VCLMA_RS04570	COG3118	belongs to the thioredoxin family
VCLMA_RS04575	COG0300	oxidoreductase activity
VCLMA_RS04585	COG0622	Phosphoesterase
VCLMA_RS04600	COG3710	Transcriptional regulator
VCLMA_RS04605	COG0326	Molecular chaperone. Has ATPase activity
VCLMA_RS04610	COG0563	adenylate kinase activity
VCLMA_RS04615	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
VCLMA_RS04630	COG0367	asparagine synthase
VCLMA_RS04635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
VCLMA_RS04635	COG4651	solute:proton antiporter activity
VCLMA_RS04640	COG1846	Transcriptional regulator
VCLMA_RS04640	COG1940	carbohydrate kinase activity
VCLMA_RS04650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCLMA_RS04650	COG1263	PTS System
VCLMA_RS04650	COG2190	(PTS) system
VCLMA_RS04675	COG0101	tRNA pseudouridine synthase activity
VCLMA_RS04680	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
VCLMA_RS04685	COG0285	dihydrofolate synthase activity
VCLMA_RS04690	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
VCLMA_RS04695	COG1286	toxin biosynthetic process
VCLMA_RS04700	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
VCLMA_RS04705	COG2056	Na+-H+ antiporter family
VCLMA_RS04710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
VCLMA_RS04730	COG0346	lactoylglutathione lyase activity
VCLMA_RS04735	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
VCLMA_RS04740	COG4660	Part of a membrane complex involved in electron transport
VCLMA_RS04755	COG4656	Part of a membrane complex involved in electron transport
VCLMA_RS04760	COG2878	Part of a membrane complex involved in electron transport
VCLMA_RS04765	COG4657	Part of a membrane complex involved in electron transport
VCLMA_RS04775	COG0556	nucleotide-excision repair
VCLMA_RS04785	COG2204	response regulator
VCLMA_RS04790	COG2198	Histidine kinase
VCLMA_RS04795	COG0391	Required for morphogenesis under gluconeogenic growth conditions
VCLMA_RS04800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
VCLMA_RS04810	COG0315	cyclic pyranopterin monophosphate synthase activity
VCLMA_RS04815	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
VCLMA_RS04820	COG0314	molybdopterin synthase activity
VCLMA_RS04830	COG0517	IMP dehydrogenase activity
VCLMA_RS04830	COG0617	tRNA 3'-terminal CCA addition
VCLMA_RS04830	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
VCLMA_RS04845	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
VCLMA_RS04855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCLMA_RS04855	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCLMA_RS04870	COG0572	uridine kinase
VCLMA_RS04875	COG2982	Protein involved in outer membrane biogenesis
VCLMA_RS04880	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
VCLMA_RS04895	COG2067	long-chain fatty acid transport protein
VCLMA_RS04910	COG0183	Belongs to the thiolase family
VCLMA_RS04915	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCLMA_RS04915	COG1024	Enoyl-CoA hydratase
VCLMA_RS04920	COG0778	Nitroreductase
VCLMA_RS04925	COG0583	DNA-binding transcription factor activity
VCLMA_RS04930	COG0745	RESPONSE REGULATOR receiver
VCLMA_RS04940	COG2832	Protein of unknown function (DUF454)
VCLMA_RS04945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
VCLMA_RS04955	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
VCLMA_RS04960	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
VCLMA_RS04970	COG2983	Belongs to the UPF0260 family
VCLMA_RS04975	COG1028	Short-chain dehydrogenase reductase Sdr
VCLMA_RS04980	COG0616	signal peptide processing
VCLMA_RS04990	COG1522	sequence-specific DNA binding
VCLMA_RS04995	COG1946	Acyl-CoA thioesterase
VCLMA_RS05015	COG3706	GGDEF domain
VCLMA_RS05020	COG0640	Transcriptional regulator
VCLMA_RS05025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCLMA_RS05050	COG1881	PFAM PEBP family protein
VCLMA_RS05070	COG0009	L-threonylcarbamoyladenylate synthase
VCLMA_RS05085	COG2201	protein-glutamate methylesterase activity
VCLMA_RS05095	COG5002	protein histidine kinase activity
VCLMA_RS05100	COG4191	Histidine kinase
VCLMA_RS05105	COG5001	Diguanylate cyclase
VCLMA_RS05105	COG3300	MHYT domain
VCLMA_RS05110	COG2204	response regulator
VCLMA_RS05130	COG0601	transmembrane transport
VCLMA_RS05135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
VCLMA_RS05140	COG0444	Belongs to the ABC transporter superfamily
VCLMA_RS05145	COG4608	Belongs to the ABC transporter superfamily
VCLMA_RS05150	COG0435	Glutathione S-transferase
VCLMA_RS05180	COG4120	Belongs to the binding-protein-dependent transport system permease family
VCLMA_RS05190	COG2203	Gaf domain
VCLMA_RS05190	COG2199	diguanylate cyclase activity
VCLMA_RS05195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
VCLMA_RS05200	COG0653	protein targeting
VCLMA_RS05205	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
VCLMA_RS05210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
VCLMA_RS05215	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
VCLMA_RS05225	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
VCLMA_RS05230	COG0156	8-amino-7-oxononanoate synthase activity
VCLMA_RS05235	COG2226	methyltransferase
VCLMA_RS05240	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
VCLMA_RS05250	COG0501	Belongs to the peptidase M48B family
VCLMA_RS05260	COG0300	oxidoreductase activity
VCLMA_RS05275	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
VCLMA_RS05285	COG2268	Band 7 protein
VCLMA_RS05295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
VCLMA_RS05300	COG2915	High frequency lysogenization protein hflD homolog
VCLMA_RS05305	COG0482	sulfurtransferase activity
VCLMA_RS05310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
VCLMA_RS05315	COG2916	Histone family protein nucleoid-structuring protein H-NS
VCLMA_RS05325	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
VCLMA_RS05330	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
VCLMA_RS05335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
VCLMA_RS05340	COG0131	Imidazoleglycerol-phosphate dehydratase
VCLMA_RS05340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
VCLMA_RS05345	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
VCLMA_RS05350	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
VCLMA_RS05355	COG0107	imidazoleglycerol-phosphate synthase activity
VCLMA_RS05360	COG0140	phosphoribosyl-ATP diphosphatase activity
VCLMA_RS05360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
VCLMA_RS05365	COG1187	pseudouridine synthase activity
VCLMA_RS05375	COG1278	Cold shock
VCLMA_RS05380	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
VCLMA_RS05385	COG0542	response to heat
VCLMA_RS05390	COG3273	potassium ion transport
VCLMA_RS05390	COG2985	domain, Protein
VCLMA_RS05395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCLMA_RS05400	COG1979	alcohol dehydrogenase
VCLMA_RS05405	COG1737	Transcriptional regulator
VCLMA_RS05410	COG0076	glutamate decarboxylase activity
VCLMA_RS05420	COG2431	L-lysine efflux transmembrane transporter activity
VCLMA_RS05430	COG3070	regulator of competence-specific genes
VCLMA_RS05445	COG3852	Histidine kinase
VCLMA_RS05455	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
VCLMA_RS05470	COG4067	protein conserved in archaea
VCLMA_RS05470	COG0189	ligase activity
VCLMA_RS05475	COG0500	methyltransferase
VCLMA_RS05480	COG4106	trans-aconitate 2-methyltransferase activity
VCLMA_RS05485	COG1801	Protein of unknown function DUF72
VCLMA_RS05490	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
VCLMA_RS05495	COG1435	thymidine kinase activity
VCLMA_RS05505	COG0159	tryptophan synthase activity
VCLMA_RS05510	COG0133	tryptophan synthase activity
VCLMA_RS05515	COG0134	indole-3-glycerol-phosphate synthase activity
VCLMA_RS05515	COG0135	phosphoribosylanthranilate isomerase activity
VCLMA_RS05525	COG0512	Glutamine amidotransferase of anthranilate synthase
VCLMA_RS05530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCLMA_RS05540	COG0613	PHP domain protein
VCLMA_RS05545	COG0009	L-threonylcarbamoyladenylate synthase
VCLMA_RS05550	COG1187	pseudouridine synthase activity
VCLMA_RS05555	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
VCLMA_RS05565	COG0492	ferredoxin-NADP+ reductase activity
VCLMA_RS05575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCLMA_RS05580	COG3706	GGDEF domain
VCLMA_RS05585	COG2949	membrane
VCLMA_RS05625	COG2885	chlorophyll binding
VCLMA_RS05660	COG2986	histidine ammonia-lyase
VCLMA_RS05665	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
VCLMA_RS05670	COG0010	Belongs to the arginase family
VCLMA_RS05675	COG1228	amidohydrolase
VCLMA_RS05690	COG3099	Belongs to the UPF0263 family
VCLMA_RS05695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCLMA_RS05705	COG5001	Diguanylate cyclase
VCLMA_RS05710	COG0417	DNA replication proofreading
VCLMA_RS05715	COG2197	response regulator
VCLMA_RS05720	COG0322	excinuclease ABC activity
VCLMA_RS05760	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
VCLMA_RS05770	COG0776	regulation of translation
VCLMA_RS05815	COG1346	cytolysis
VCLMA_RS05820	COG1380	Effector of murein hydrolase LrgA
VCLMA_RS05825	COG2925	Exonuclease
VCLMA_RS05830	COG1823	symporter activity
VCLMA_RS05835	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCLMA_RS05840	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
VCLMA_RS05845	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
VCLMA_RS05860	COG2988	succinylglutamate desuccinylase activity
VCLMA_RS05865	COG4139	cobalamin transport
VCLMA_RS05870	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
VCLMA_RS05915	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCLMA_RS05920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
VCLMA_RS05925	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCLMA_RS05935	COG1054	Belongs to the UPF0176 family
VCLMA_RS05945	COG2814	Major facilitator Superfamily
VCLMA_RS05955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
VCLMA_RS05985	COG3108	Peptidase M15
VCLMA_RS05990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCLMA_RS06030	COG1846	Transcriptional regulator
VCLMA_RS06035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
VCLMA_RS06040	COG0726	polysaccharide deacetylase
VCLMA_RS06045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
VCLMA_RS06055	COG1447	Phosphotransferase system cellobiose-specific component IIA
VCLMA_RS06060	COG1486	melibiose metabolic process
VCLMA_RS06065	COG3394	polysaccharide catabolic process
VCLMA_RS06070	COG1609	Transcriptional regulator
VCLMA_RS06075	COG2943	transferase activity, transferring hexosyl groups
VCLMA_RS06080	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
VCLMA_RS06085	COG0840	transmembrane signaling receptor activity
VCLMA_RS06100	COG1448	Aminotransferase
VCLMA_RS06110	COG2770	Histidine kinase
VCLMA_RS06110	COG3437	response regulator, receiver
VCLMA_RS06115	COG0351	phosphomethylpyrimidine kinase
VCLMA_RS06120	COG0017	Asparaginyl-tRNA synthetase
VCLMA_RS06125	COG0840	transmembrane signaling receptor activity
VCLMA_RS06130	COG0720	synthase
VCLMA_RS06135	COG1760	l-serine dehydratase
VCLMA_RS06140	COG0814	amino acid
VCLMA_RS06145	COG0494	nUDIX hydrolase
VCLMA_RS06150	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
VCLMA_RS06165	COG3106	COG3106 Predicted ATPase
VCLMA_RS06170	COG3768	UPF0283 membrane protein
VCLMA_RS06180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
VCLMA_RS06205	COG0471	metal ion transport
VCLMA_RS06210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCLMA_RS06210	COG4191	Histidine kinase
VCLMA_RS06220	COG2990	Protein conserved in bacteria
VCLMA_RS06225	COG3713	MltA-interacting MipA family protein
VCLMA_RS06230	COG5002	protein histidine kinase activity
VCLMA_RS06235	COG0745	RESPONSE REGULATOR receiver
VCLMA_RS06310	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
VCLMA_RS06315	COG0372	Belongs to the citrate synthase family
VCLMA_RS06345	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCLMA_RS06365	COG0625	glutathione transferase activity
VCLMA_RS06370	COG3437	response regulator, receiver
VCLMA_RS06390	COG3706	GGDEF domain
VCLMA_RS06395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCLMA_RS06400	COG1254	Belongs to the acylphosphatase family
VCLMA_RS06405	COG2920	part of a sulfur-relay system
VCLMA_RS06410	COG0670	Belongs to the BI1 family
VCLMA_RS06415	COG1126	abc transporter atp-binding protein
VCLMA_RS06420	COG0765	amino acid transport
VCLMA_RS06425	COG4597	amino acid ABC transporter
VCLMA_RS06430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
VCLMA_RS06440	COG0561	phosphatase activity
VCLMA_RS06445	COG0602	queuosine metabolic process
VCLMA_RS06450	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
VCLMA_RS06480	COG3706	GGDEF domain
VCLMA_RS06490	COG0443	Heat shock 70 kDa protein
VCLMA_RS06530	COG1643	Atp-dependent helicase
VCLMA_RS06545	COG0095	Lipoate-protein ligase
VCLMA_RS06555	COG0583	DNA-binding transcription factor activity
VCLMA_RS06560	COG0477	Major facilitator Superfamily
VCLMA_RS06565	COG0415	Belongs to the DNA photolyase family
VCLMA_RS06580	COG0745	RESPONSE REGULATOR receiver
VCLMA_RS06590	COG0643	Histidine kinase
VCLMA_RS06590	COG2198	Histidine kinase
VCLMA_RS06595	COG2198	Histidine kinase
VCLMA_RS06595	COG0784	Response regulator, receiver
VCLMA_RS06595	COG0643	Histidine kinase
VCLMA_RS06600	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCLMA_RS06610	COG2201	protein-glutamate methylesterase activity
VCLMA_RS06615	COG0835	chemotaxis
VCLMA_RS06620	COG0840	transmembrane signaling receptor activity
VCLMA_RS06635	COG0513	Belongs to the DEAD box helicase family
VCLMA_RS06650	COG1566	PFAM secretion protein HlyD family protein
VCLMA_RS06655	COG2814	Major facilitator Superfamily
VCLMA_RS06665	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
VCLMA_RS06680	COG3501	Rhs element vgr protein
VCLMA_RS06685	COG1280	lysine exporter protein (LysE YggA)
VCLMA_RS06690	COG1115	amino acid carrier protein
VCLMA_RS06715	COG1177	transmembrane transport
VCLMA_RS06725	COG3842	ATPase activity
VCLMA_RS06745	COG0037	tRNA processing
VCLMA_RS06750	COG0589	response to stress
VCLMA_RS06755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
VCLMA_RS06780	COG2010	Cytochrome c
VCLMA_RS06795	COG3278	Belongs to the heme-copper respiratory oxidase family
VCLMA_RS06810	COG0784	Response regulator, receiver
VCLMA_RS06810	COG2205	protein histidine kinase activity
VCLMA_RS06835	COG2994	toxin metabolic process
VCLMA_RS06840	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
VCLMA_RS06840	COG3064	Membrane
VCLMA_RS06840	COG1073	alpha beta
VCLMA_RS06865	COG3120	sequence-specific DNA binding
VCLMA_RS06870	COG1067	ATP-dependent peptidase activity
VCLMA_RS06875	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCLMA_RS06890	COG0488	(ABC) transporter
VCLMA_RS06900	COG0116	Belongs to the methyltransferase superfamily
VCLMA_RS06900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
VCLMA_RS06910	COG0167	dihydroorotate dehydrogenase activity
VCLMA_RS06925	COG0308	aminopeptidase N
VCLMA_RS06940	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
VCLMA_RS06945	COG1956	GAF domain-containing protein
VCLMA_RS06950	COG1132	(ABC) transporter
VCLMA_RS06955	COG2995	paraquat-inducible protein a
VCLMA_RS06960	COG3008	intermembrane lipid transfer
VCLMA_RS06970	COG2996	Protein conserved in bacteria
VCLMA_RS06985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
VCLMA_RS06990	COG1666	GTP binding
VCLMA_RS06995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
VCLMA_RS07010	COG0437	4 iron, 4 sulfur cluster binding
VCLMA_RS07045	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
VCLMA_RS07050	COG0488	(ABC) transporter
VCLMA_RS07055	COG3852	Histidine kinase
VCLMA_RS07060	COG2204	response regulator
VCLMA_RS07070	COG4662	Binding-protein-dependent transport system inner membrane component
VCLMA_RS07075	COG3842	ATPase activity
VCLMA_RS07080	COG0746	molybdenum cofactor guanylyltransferase activity
VCLMA_RS07085	COG0303	'Molybdopterin
VCLMA_RS07100	COG1940	carbohydrate kinase activity
VCLMA_RS07105	COG3148	PFAM DTW domain containing protein
VCLMA_RS07115	COG0840	transmembrane signaling receptor activity
VCLMA_RS07120	COG0791	NLP P60 protein
VCLMA_RS07130	COG3001	Fructosamine kinase
VCLMA_RS07140	COG0534	Mate efflux family protein
VCLMA_RS07150	COG1793	dna ligase
VCLMA_RS07160	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
VCLMA_RS07165	COG0848	biopolymer transport protein
VCLMA_RS07175	COG0811	peptide transport
VCLMA_RS07190	COG1175	transmembrane transport
VCLMA_RS07195	COG0395	ABC-type sugar transport system, permease component
VCLMA_RS07205	COG1349	DNA-binding transcription factor activity
VCLMA_RS07210	COG0584	glycerophosphoryl diester phosphodiesterase
VCLMA_RS07215	COG2731	YhcH YjgK YiaL family protein
VCLMA_RS07220	COG0251	oxidation-reduction process
VCLMA_RS07225	COG1609	Transcriptional regulator
VCLMA_RS07230	COG2723	6-phospho-beta-galactosidase activity
VCLMA_RS07260	COG1136	(ABC) transporter
VCLMA_RS07260	COG0577	efflux transmembrane transporter activity
VCLMA_RS07265	COG1136	(ABC) transporter
VCLMA_RS07265	COG0577	efflux transmembrane transporter activity
VCLMA_RS07270	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCLMA_RS07270	COG1136	(ABC) transporter
VCLMA_RS07275	COG1294	oxidase, subunit
VCLMA_RS07280	COG1271	oxidase subunit
VCLMA_RS07305	COG3097	Belongs to the UPF0267 family
VCLMA_RS07320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCLMA_RS07330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
VCLMA_RS07365	COG3527	Alpha-acetolactate decarboxylase
VCLMA_RS07380	COG2200	EAL domain
VCLMA_RS07380	COG2199	diguanylate cyclase activity
VCLMA_RS07390	COG2017	converts alpha-aldose to the beta-anomer
VCLMA_RS07395	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
VCLMA_RS07400	COG1085	galactose-1-phosphate uridylyltransferase
VCLMA_RS07440	COG0835	chemotaxis
VCLMA_RS07440	COG0784	Response regulator, receiver
VCLMA_RS07450	COG4565	transcriptional regulatory protein
VCLMA_RS07455	COG3290	protein histidine kinase activity
VCLMA_RS07470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCLMA_RS07490	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
VCLMA_RS07495	COG3063	Type IV pilus biogenesis stability protein PilW
VCLMA_RS07510	COG1451	nucleotide metabolic process
VCLMA_RS07560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
VCLMA_RS07570	COG0577	efflux transmembrane transporter activity
VCLMA_RS07575	COG4181	ATPase activity
VCLMA_RS07580	COG0534	Mate efflux family protein
VCLMA_RS07585	COG0702	epimerase
VCLMA_RS07595	COG2814	Major facilitator Superfamily
VCLMA_RS07600	COG1187	pseudouridine synthase activity
VCLMA_RS07605	COG1061	Type III restriction enzyme res subunit
VCLMA_RS07625	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
VCLMA_RS07630	COG2203	Gaf domain
VCLMA_RS07630	COG5001	Diguanylate cyclase
VCLMA_RS07630	COG3706	GGDEF domain
VCLMA_RS07630	COG4251	negative regulation of phosphorylation
VCLMA_RS07675	COG4934	collagen metabolic process
VCLMA_RS07690	COG0784	Response regulator, receiver
VCLMA_RS07690	COG2205	protein histidine kinase activity
VCLMA_RS07695	COG2239	Acts as a magnesium transporter
VCLMA_RS07705	COG0814	amino acid
VCLMA_RS07710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCLMA_RS07715	COG1131	(ABC) transporter
VCLMA_RS07720	COG0842	Transport permease protein
VCLMA_RS07730	COG3313	Fe-S protein
VCLMA_RS07740	COG4134	Bacterial extracellular solute-binding protein
VCLMA_RS07745	COG4135	transport system, permease component
VCLMA_RS07750	COG4136	ATPase activity
VCLMA_RS07755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
VCLMA_RS07760	COG0564	pseudouridine synthase activity
VCLMA_RS07765	COG0733	neurotransmitter:sodium symporter activity
VCLMA_RS07780	COG0626	cystathionine gamma-synthase activity
VCLMA_RS07785	COG0626	cystathionine gamma-synthase activity
VCLMA_RS07790	COG2818	Glycosylase
VCLMA_RS07805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
VCLMA_RS07820	COG1842	Phage shock protein A
VCLMA_RS07825	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
VCLMA_RS07835	COG4168	peptide transport system, permease
VCLMA_RS07850	COG4172	Belongs to the ABC transporter superfamily
VCLMA_RS07865	COG1227	inorganic diphosphatase activity
VCLMA_RS07885	COG3005	denitrification pathway
VCLMA_RS07890	COG4459	periplasmic nitrate reductase
VCLMA_RS07895	COG2116	formate transmembrane transporter activity
VCLMA_RS07905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
VCLMA_RS07925	COG1607	acyl-coa hydrolase
VCLMA_RS07930	COG2350	Protein conserved in bacteria
VCLMA_RS07940	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
VCLMA_RS07945	COG0583	DNA-binding transcription factor activity
VCLMA_RS07965	COG5001	Diguanylate cyclase
VCLMA_RS07970	COG1032	radical SAM domain protein
VCLMA_RS07990	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
VCLMA_RS07995	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
VCLMA_RS08000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
VCLMA_RS08005	COG1434	Gram-negative-bacterium-type cell wall biogenesis
VCLMA_RS08010	COG0745	RESPONSE REGULATOR receiver
VCLMA_RS08015	COG3381	protein complex oligomerization
VCLMA_RS08025	COG3070	regulator of competence-specific genes
VCLMA_RS08045	COG0297	glycogen (starch) synthase activity
VCLMA_RS08075	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
VCLMA_RS08085	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
VCLMA_RS08090	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
VCLMA_RS08095	COG1960	acyl-CoA dehydrogenase activity
VCLMA_RS08115	COG1012	belongs to the aldehyde dehydrogenase family
VCLMA_RS08120	COG1309	transcriptional regulator
VCLMA_RS08160	COG0582	viral genome integration into host DNA
VCLMA_RS08170	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
VCLMA_RS08175	COG1737	Transcriptional regulator
VCLMA_RS08180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
VCLMA_RS08185	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCLMA_RS08190	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCLMA_RS08195	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCLMA_RS08210	COG1940	carbohydrate kinase activity
VCLMA_RS08215	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
VCLMA_RS08220	COG4409	exo-alpha-(2->6)-sialidase activity
VCLMA_RS08230	COG2003	Belongs to the UPF0758 family
VCLMA_RS08250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCLMA_RS08265	COG1940	carbohydrate kinase activity
VCLMA_RS08320	COG0415	Belongs to the DNA photolyase family
VCLMA_RS08330	COG4628	conserved protein (DUF2132)
VCLMA_RS08335	COG3284	Transcriptional regulator
VCLMA_RS08340	COG1012	belongs to the aldehyde dehydrogenase family
VCLMA_RS08350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCLMA_RS08355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCLMA_RS08360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCLMA_RS08370	COG2207	Transcriptional regulator
VCLMA_RS08375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCLMA_RS08375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCLMA_RS08375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
VCLMA_RS08390	COG5002	protein histidine kinase activity
VCLMA_RS08390	COG0784	Response regulator, receiver
VCLMA_RS08400	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
VCLMA_RS08410	COG2885	chlorophyll binding
VCLMA_RS08415	COG0823	Involved in the tonB-independent uptake of proteins
VCLMA_RS08430	COG0811	peptide transport
VCLMA_RS08435	COG0824	Thioesterase
VCLMA_RS08440	COG3790	cyd operon protein YbgE
VCLMA_RS08445	COG4890	Cyd operon protein YbgT
VCLMA_RS08450	COG1294	oxidase, subunit
VCLMA_RS08455	COG1271	oxidase subunit
VCLMA_RS08465	COG0632	four-way junction helicase activity
VCLMA_RS08470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
VCLMA_RS08475	COG0215	cysteine-tRNA ligase activity
VCLMA_RS08480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
VCLMA_RS08485	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCLMA_RS08490	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
VCLMA_RS08495	COG3012	SEC-C Motif Domain Protein
VCLMA_RS08500	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
VCLMA_RS08505	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
VCLMA_RS08510	COG1199	ATP-dependent helicase activity
VCLMA_RS08515	COG0730	response to heat
VCLMA_RS08520	COG3923	Primosomal replication protein n
VCLMA_RS08530	COG0840	transmembrane signaling receptor activity
VCLMA_RS08535	COG0708	Exodeoxyribonuclease III
VCLMA_RS08540	COG4160	amino acid transport
VCLMA_RS08580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
VCLMA_RS08590	COG3013	Belongs to the UPF0304 family
VCLMA_RS08595	COG2766	serine protein kinase
VCLMA_RS08610	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
VCLMA_RS08615	COG2835	tetraacyldisaccharide 4'-kinase activity
VCLMA_RS08620	COG1663	tetraacyldisaccharide 4'-kinase activity
VCLMA_RS08625	COG1132	(ABC) transporter
VCLMA_RS08630	COG2333	competence protein COMEC
VCLMA_RS08630	COG0658	competence protein
VCLMA_RS08640	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCLMA_RS08645	COG1136	(ABC) transporter
VCLMA_RS08650	COG4591	ABC-type transport system involved in lipoprotein release permease component
VCLMA_RS08680	COG1252	NADH dehydrogenase
VCLMA_RS08685	COG3150	esterase
VCLMA_RS08710	COG0537	adenosine 5'-monophosphoramidase activity
VCLMA_RS08725	COG2186	Transcriptional regulator
VCLMA_RS08735	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
VCLMA_RS08740	COG1674	ftsk spoiiie
VCLMA_RS08750	COG0686	Belongs to the AlaDH PNT family
VCLMA_RS08760	COG0583	DNA-binding transcription factor activity
VCLMA_RS08780	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
VCLMA_RS08785	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
VCLMA_RS08790	COG0776	regulation of translation
VCLMA_RS08795	COG0539	negative regulation of cytoplasmic translation
VCLMA_RS08800	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
VCLMA_RS08805	COG1555	photosystem II stabilization
VCLMA_RS08810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
VCLMA_RS08815	COG0776	regulation of translation
VCLMA_RS08825	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
VCLMA_RS08835	COG0544	peptidyl-prolyl cis-trans isomerase activity
VCLMA_RS08845	COG4191	Histidine kinase
VCLMA_RS08855	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
VCLMA_RS08860	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
VCLMA_RS08865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
VCLMA_RS08870	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
VCLMA_RS08885	COG5001	Diguanylate cyclase
VCLMA_RS08885	COG3300	MHYT domain
VCLMA_RS08895	COG4589	Belongs to the CDS family
VCLMA_RS08930	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
VCLMA_RS08940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCLMA_RS08955	COG0243	molybdopterin cofactor binding
VCLMA_RS08960	COG3005	denitrification pathway
VCLMA_RS08965	COG3469	chitinase activity
VCLMA_RS08965	COG3325	Belongs to the glycosyl hydrolase 18 family
VCLMA_RS08970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCLMA_RS08980	COG2951	lytic endotransglycosylase activity
VCLMA_RS08985	COG3100	YcgL domain-containing protein
VCLMA_RS08990	COG0850	regulation of cytokinetic process
VCLMA_RS08995	COG2894	cell division
VCLMA_RS09000	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
VCLMA_RS09005	COG3015	lipoprotein NlpE involved in copper resistance
VCLMA_RS09035	COG0840	transmembrane signaling receptor activity
VCLMA_RS09040	COG1396	sequence-specific DNA binding
VCLMA_RS09045	COG3135	benzoate transporter
VCLMA_RS09065	COG0596	Alpha beta hydrolase
VCLMA_RS09070	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
VCLMA_RS09075	COG1169	isochorismate synthase
VCLMA_RS09080	COG0436	Aminotransferase
VCLMA_RS09085	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
VCLMA_RS09090	COG0232	Belongs to the dGTPase family. Type 2 subfamily
VCLMA_RS09110	COG0318	PFAM AMP-dependent synthetase and ligase
VCLMA_RS09115	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
VCLMA_RS09120	COG0318	PFAM AMP-dependent synthetase and ligase
VCLMA_RS09125	COG0596	Alpha beta hydrolase
VCLMA_RS09140	COG1214	PFAM Peptidase M22, glycoprotease
VCLMA_RS09145	COG1199	ATP-dependent helicase activity
VCLMA_RS09155	COG0788	formyltetrahydrofolate deformylase activity
VCLMA_RS09160	COG0446	pyridine nucleotide-disulphide oxidoreductase
VCLMA_RS09160	COG1902	pentaerythritol trinitrate reductase activity
VCLMA_RS09165	COG0616	signal peptide processing
VCLMA_RS09170	COG0252	asparaginase activity
VCLMA_RS09175	COG3139	Protein of unknown function (DUF1315)
VCLMA_RS09185	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCLMA_RS09190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
VCLMA_RS09195	COG0676	glucose-6-phosphate 1-epimerase activity
VCLMA_RS09205	COG2226	methyltransferase
VCLMA_RS09220	COG0835	chemotaxis
VCLMA_RS09220	COG0784	Response regulator, receiver
VCLMA_RS09225	COG1940	carbohydrate kinase activity
VCLMA_RS09235	COG4667	esterase of the alpha-beta hydrolase superfamily
VCLMA_RS09250	COG0733	neurotransmitter:sodium symporter activity
VCLMA_RS09255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
VCLMA_RS09255	COG1263	PTS System
VCLMA_RS09260	COG0084	hydrolase, TatD family'
VCLMA_RS09270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
VCLMA_RS09275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
VCLMA_RS09280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
VCLMA_RS09285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCLMA_RS09290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
VCLMA_RS09295	COG1028	Short-chain dehydrogenase reductase Sdr
VCLMA_RS09305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
VCLMA_RS09310	COG0416	fatty acid biosynthetic process
VCLMA_RS09315	COG0333	Belongs to the bacterial ribosomal protein bL32 family
VCLMA_RS09320	COG1399	metal-binding, possibly nucleic acid-binding protein
VCLMA_RS09325	COG0424	maF-like protein
VCLMA_RS09330	COG0564	pseudouridine synthase activity
VCLMA_RS09340	COG1530	ribonuclease E activity
VCLMA_RS09345	COG0659	secondary active sulfate transmembrane transporter activity
VCLMA_RS09355	COG1454	alcohol dehydrogenase
VCLMA_RS09355	COG1012	belongs to the aldehyde dehydrogenase family
VCLMA_RS09360	COG2095	MarC family integral membrane protein
VCLMA_RS09365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCLMA_RS09370	COG1757	Na H antiporter
VCLMA_RS09380	COG3081	Nucleoid-associated protein
VCLMA_RS09385	COG3082	Protein of unknown function (DUF1414)
VCLMA_RS09390	COG3083	sulfuric ester hydrolase activity
VCLMA_RS09405	COG0123	including yeast histone deacetylase and acetoin utilization protein
VCLMA_RS09410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
VCLMA_RS09415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
VCLMA_RS09435	COG2853	Lipoprotein
VCLMA_RS09445	COG3088	subunit of a heme lyase
VCLMA_RS09445	COG4235	cytochrome complex assembly
VCLMA_RS09450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
VCLMA_RS09455	COG1138	Cytochrome C-type biogenesis protein
VCLMA_RS09460	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
VCLMA_RS09470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCLMA_RS09475	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
VCLMA_RS09480	COG4133	protoheme IX ABC transporter activity
VCLMA_RS09490	COG0835	chemotaxis
VCLMA_RS09500	COG1192	Involved in chromosome partitioning
VCLMA_RS09505	COG2201	protein-glutamate methylesterase activity
VCLMA_RS09510	COG0643	Histidine kinase
VCLMA_RS09510	COG2198	Histidine kinase
VCLMA_RS09510	COG0784	Response regulator, receiver
VCLMA_RS09515	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
VCLMA_RS09545	COG2062	phosphohistidine phosphatase, SixA
VCLMA_RS09550	COG1025	Belongs to the peptidase M16 family
VCLMA_RS09560	COG0018	arginyl-trna synthetase
VCLMA_RS09580	COG1918	ferrous iron import across plasma membrane
VCLMA_RS09585	COG4977	sequence-specific DNA binding
VCLMA_RS09590	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
VCLMA_RS09595	COG1121	(ABC) transporter
VCLMA_RS09600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
VCLMA_RS09610	COG0045	succinate-CoA ligase (ADP-forming) activity
VCLMA_RS09615	COG0508	dehydrogenase complex catalyzes the overall conversion of
VCLMA_RS09620	COG0567	Dehydrogenase, E1 component
VCLMA_RS09630	COG1053	succinate dehydrogenase
VCLMA_RS09635	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
VCLMA_RS09640	COG2009	succinate dehydrogenase
VCLMA_RS09645	COG0372	Belongs to the citrate synthase family
VCLMA_RS09650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
VCLMA_RS09660	COG0033	Phosphoglucomutase
VCLMA_RS09665	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
VCLMA_RS09670	COG0596	Alpha beta hydrolase
VCLMA_RS09685	COG1346	cytolysis
VCLMA_RS09695	COG0583	DNA-binding transcription factor activity
VCLMA_RS09705	COG0735	belongs to the Fur family
VCLMA_RS09710	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
VCLMA_RS09715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCLMA_RS09720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
VCLMA_RS09730	COG0431	NADPH-dependent FMN reductase
VCLMA_RS09740	COG3101	peptidyl-lysine hydroxylation
VCLMA_RS09745	COG2860	membrane
VCLMA_RS09750	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
VCLMA_RS09760	COG2890	protein-(glutamine-N5) methyltransferase activity
VCLMA_RS09765	COG2840	Smr protein MutS2
VCLMA_RS09775	COG1684	flagellar biosynthetic protein fliR
VCLMA_RS09780	COG1987	bacterial-type flagellum assembly
VCLMA_RS09805	COG1580	Controls the rotational direction of flagella during chemotaxis
VCLMA_RS09825	COG1317	bacterial-type flagellum organization
VCLMA_RS09830	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
VCLMA_RS09840	COG1677	Flagellar hook-basal body complex protein FliE
VCLMA_RS09860	COG1516	flagellar protein fliS
VCLMA_RS09870	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
VCLMA_RS09875	COG1334	flagellar protein FlaG
VCLMA_RS09885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCLMA_RS09890	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCLMA_RS09895	COG2837	iron assimilation
VCLMA_RS09915	COG1393	Belongs to the ArsC family
VCLMA_RS09925	COG1876	peptidase activity
VCLMA_RS09935	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
VCLMA_RS09950	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VCLMA_RS09970	COG4783	chaperone-mediated protein folding
VCLMA_RS09975	COG1393	Belongs to the ArsC family
VCLMA_RS09995	COG2233	PERMEase
VCLMA_RS10000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
VCLMA_RS10005	COG0737	Belongs to the 5'-nucleotidase family
VCLMA_RS10010	COG2877	3-deoxy-8-phosphooctulonate synthase activity
VCLMA_RS10015	COG2912	Transglutaminase-like superfamily
VCLMA_RS10030	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
VCLMA_RS10035	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
VCLMA_RS10040	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
VCLMA_RS10045	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
VCLMA_RS10050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
VCLMA_RS10055	COG0193	aminoacyl-tRNA hydrolase activity
VCLMA_RS10060	COG0012	GTP binding
VCLMA_RS10145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCLMA_RS10150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
VCLMA_RS10170	COG3951	Flagellar rod assembly protein muramidase FlgJ
VCLMA_RS10170	COG1705	Flagellar rod assembly protein muramidase FlgJ
VCLMA_RS10175	COG1706	bacterial-type flagellum-dependent cell motility
VCLMA_RS10180	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
VCLMA_RS10190	COG4787	bacterial-type flagellum-dependent cell motility
VCLMA_RS10195	COG1749	Flagellar hook protein flgE
VCLMA_RS10210	COG1815	bacterial-type flagellum-dependent cell motility
VCLMA_RS10215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
VCLMA_RS10220	COG0835	chemotaxis
VCLMA_RS10220	COG0784	Response regulator, receiver
VCLMA_RS10255	COG2226	methyltransferase
VCLMA_RS10255	COG3433	isochorismatase activity
VCLMA_RS10255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
VCLMA_RS10260	COG2375	cellular response to nickel ion
VCLMA_RS10265	COG1629	transport
VCLMA_RS10265	COG4774	siderophore transport
VCLMA_RS10280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
VCLMA_RS10285	COG2608	mercury ion transmembrane transporter activity
VCLMA_RS10285	COG2217	Heavy metal translocating P-type atpase
VCLMA_RS10300	COG3735	TraB family
VCLMA_RS10315	COG2840	Smr protein MutS2
VCLMA_RS10320	COG1187	pseudouridine synthase activity
VCLMA_RS10330	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
VCLMA_RS10335	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
VCLMA_RS10340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
VCLMA_RS10345	COG0121	glutamine amidotransferase
VCLMA_RS10350	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
VCLMA_RS10355	COG1960	acyl-CoA dehydrogenase activity
VCLMA_RS10370	COG0328	RNA-DNA hybrid ribonuclease activity
VCLMA_RS10375	COG2226	methyltransferase
VCLMA_RS10380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
VCLMA_RS10385	COG1388	LysM domain
VCLMA_RS10385	COG0741	lytic transglycosylase activity
VCLMA_RS10390	COG3021	interspecies interaction between organisms
VCLMA_RS10395	COG0347	Belongs to the P(II) protein family
VCLMA_RS10400	COG3479	Phenolic acid decarboxylase
VCLMA_RS10410	COG0037	tRNA processing
VCLMA_RS10415	COG0825	malonyl-CoA metabolic process
VCLMA_RS10420	COG0587	DNA-directed DNA polymerase activity
VCLMA_RS10430	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCLMA_RS10435	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCLMA_RS10440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
VCLMA_RS10445	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
VCLMA_RS10450	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
VCLMA_RS10460	COG0750	zinc metalloprotease
VCLMA_RS10465	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
VCLMA_RS10470	COG0575	Belongs to the CDS family
VCLMA_RS10475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
VCLMA_RS10480	COG0233	cytoplasmic translational termination
VCLMA_RS10485	COG0528	UMP kinase activity
VCLMA_RS10490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
VCLMA_RS10500	COG0024	Methionine aminopeptidase
VCLMA_RS10505	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
VCLMA_RS10515	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
VCLMA_RS10520	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
VCLMA_RS10525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
VCLMA_RS10530	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
VCLMA_RS10545	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCLMA_RS10545	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
VCLMA_RS10550	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
VCLMA_RS10555	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
VCLMA_RS10560	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
VCLMA_RS10570	COG1073	alpha beta
VCLMA_RS10575	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
VCLMA_RS10580	COG2252	PERMEase
VCLMA_RS10585	COG2195	Cleaves the N-terminal amino acid of tripeptides
VCLMA_RS10590	COG0189	ligase activity
VCLMA_RS10590	COG4067	protein conserved in archaea
VCLMA_RS10595	COG0189	ligase activity
VCLMA_RS10605	COG0733	neurotransmitter:sodium symporter activity
VCLMA_RS10610	COG3706	GGDEF domain
VCLMA_RS10630	COG1477	protein flavinylation
VCLMA_RS10635	COG2871	sodium ion transport
VCLMA_RS10640	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCLMA_RS10645	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCLMA_RS10650	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCLMA_RS10655	COG1805	sodium ion transport
VCLMA_RS10660	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
VCLMA_RS10665	COG0271	Belongs to the BolA IbaG family
VCLMA_RS10670	COG2813	Specifically methylates the guanine in position
VCLMA_RS10685	COG2211	Major facilitator Superfamily
VCLMA_RS10705	COG3248	Nucleoside-binding outer membrane protein
VCLMA_RS10710	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
VCLMA_RS10720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
VCLMA_RS10725	COG2166	iron-sulfur cluster assembly
VCLMA_RS10730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
VCLMA_RS10735	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
VCLMA_RS10745	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCLMA_RS10745	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
VCLMA_RS10760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
VCLMA_RS10765	COG1074	ATP-dependent DNA helicase activity
VCLMA_RS10770	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
VCLMA_RS10785	COG3141	response to X-ray
VCLMA_RS10790	COG2171	N-acyltransferase activity
VCLMA_RS10800	COG0456	acetyltransferase
VCLMA_RS10805	COG0189	ligase activity
VCLMA_RS10805	COG0569	domain protein
VCLMA_RS10820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
VCLMA_RS10825	COG1609	Transcriptional regulator
VCLMA_RS10830	COG3250	beta-galactosidase activity
VCLMA_RS10845	COG1022	Amp-dependent synthetase and ligase
VCLMA_RS10850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
VCLMA_RS10855	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
VCLMA_RS10865	COG0560	Phosphoserine phosphatase
VCLMA_RS10875	COG0813	purine-nucleoside phosphorylase activity
VCLMA_RS10880	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
VCLMA_RS10885	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
VCLMA_RS10890	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
VCLMA_RS10900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
VCLMA_RS10905	COG0084	hydrolase, TatD family'
VCLMA_RS10910	COG3022	response to hydroperoxide
VCLMA_RS10915	COG1115	amino acid carrier protein
VCLMA_RS10930	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
VCLMA_RS10935	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
VCLMA_RS10940	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
VCLMA_RS10950	COG0083	homoserine kinase activity
VCLMA_RS10965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCLMA_RS10975	COG0745	RESPONSE REGULATOR receiver
VCLMA_RS10980	COG5002	protein histidine kinase activity
VCLMA_RS10980	COG0784	Response regulator, receiver
VCLMA_RS10980	COG2198	Histidine kinase
VCLMA_RS10985	COG2203	Gaf domain
VCLMA_RS10985	COG4251	negative regulation of phosphorylation
VCLMA_RS10985	COG3706	GGDEF domain
VCLMA_RS10985	COG5001	Diguanylate cyclase
VCLMA_RS10990	COG1242	4 iron, 4 sulfur cluster binding
VCLMA_RS10995	COG0067	glutamate synthase
VCLMA_RS10995	COG0069	glutamate synthase activity
VCLMA_RS10995	COG0070	glutamate synthase
VCLMA_RS11005	COG0067	glutamate synthase
VCLMA_RS11005	COG0070	glutamate synthase
VCLMA_RS11005	COG0069	glutamate synthase activity
VCLMA_RS11010	COG0493	'glutamate synthase
VCLMA_RS11020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
VCLMA_RS11030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
VCLMA_RS11035	COG2860	membrane
VCLMA_RS11040	COG0583	DNA-binding transcription factor activity
VCLMA_RS11055	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
VCLMA_RS11060	COG0505	Belongs to the CarA family
VCLMA_RS11070	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
VCLMA_RS11075	COG0494	nUDIX hydrolase
VCLMA_RS11085	COG0653	protein targeting
VCLMA_RS11095	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
VCLMA_RS11100	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
VCLMA_RS11105	COG0849	cell division
VCLMA_RS11110	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
VCLMA_RS11115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCLMA_RS11125	COG0772	Belongs to the SEDS family
VCLMA_RS11130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
VCLMA_RS11140	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
VCLMA_RS11145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
VCLMA_RS11150	COG0768	penicillin binding
VCLMA_RS11155	COG3116	cell division
VCLMA_RS11165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCLMA_RS11175	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
VCLMA_RS11180	COG2186	Transcriptional regulator
VCLMA_RS11185	COG0737	Belongs to the 5'-nucleotidase family
VCLMA_RS11190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
VCLMA_RS11195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
VCLMA_RS11200	COG4974	Belongs to the 'phage' integrase family
VCLMA_RS11205	COG0716	FMN binding
VCLMA_RS11220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
VCLMA_RS11225	COG1459	type II secretion system
VCLMA_RS11235	COG0237	dephospho-CoA kinase activity
VCLMA_RS11240	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
VCLMA_RS11250	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
VCLMA_RS11255	COG0187	DNA topoisomerase II activity
VCLMA_RS11260	COG3150	esterase
VCLMA_RS11270	COG3151	Protein conserved in bacteria
VCLMA_RS11275	COG0494	nUDIX hydrolase
VCLMA_RS11280	COG1538	Outer membrane efflux protein
VCLMA_RS11290	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
VCLMA_RS11295	COG0840	transmembrane signaling receptor activity
VCLMA_RS11305	COG1392	Phosphate transport regulator
VCLMA_RS11310	COG0306	phosphate transporter
VCLMA_RS11315	COG4991	sh3 domain protein
VCLMA_RS11325	COG3267	Type II secretory pathway component ExeA
VCLMA_RS11325	COG3409	Peptidoglycan-binding domain 1 protein
VCLMA_RS11335	COG0148	phosphopyruvate hydratase activity
VCLMA_RS11340	COG0504	CTP synthase activity
VCLMA_RS11345	COG3956	TIGRFAM MazG family protein
VCLMA_RS11350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCLMA_RS11365	COG5001	Diguanylate cyclase
VCLMA_RS11380	COG0736	holo-[acyl-carrier-protein] synthase activity
VCLMA_RS11385	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
VCLMA_RS11390	COG1381	Involved in DNA repair and RecF pathway recombination
VCLMA_RS11395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
VCLMA_RS11400	COG0571	ribonuclease III activity
VCLMA_RS11410	COG0481	GTPase activity
VCLMA_RS11415	COG3086	response to oxidative stress
VCLMA_RS11430	COG1595	DNA-templated transcription, initiation
VCLMA_RS11440	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
VCLMA_RS11450	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
VCLMA_RS11465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCLMA_RS11470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
VCLMA_RS11475	COG3079	Belongs to the UPF0149 family
VCLMA_RS11480	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
VCLMA_RS11485	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
VCLMA_RS11490	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
VCLMA_RS11495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
VCLMA_RS11500	COG0440	acetolactate synthase activity
VCLMA_RS11505	COG0028	Belongs to the TPP enzyme family
VCLMA_RS11510	COG1022	Amp-dependent synthetase and ligase
VCLMA_RS11515	COG0583	DNA-binding transcription factor activity
VCLMA_RS11540	COG0473	3-isopropylmalate dehydrogenase activity
VCLMA_RS11545	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
VCLMA_RS11550	COG0066	3-isopropylmalate dehydratase activity
VCLMA_RS11605	COG3437	response regulator, receiver
VCLMA_RS11620	COG0795	lipopolysaccharide-transporting ATPase activity
VCLMA_RS11625	COG0795	lipopolysaccharide-transporting ATPase activity
VCLMA_RS11630	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
VCLMA_RS11635	COG2927	DNA polymerase III (CHI subunit)
VCLMA_RS11640	COG0525	valine-tRNA ligase activity
VCLMA_RS11645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
VCLMA_RS11650	COG0564	pseudouridine synthase activity
VCLMA_RS11675	COG0540	Belongs to the ATCase OTCase family
VCLMA_RS11685	COG0251	oxidation-reduction process
VCLMA_RS11695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
VCLMA_RS11700	COG5007	Belongs to the BolA IbaG family
VCLMA_RS11710	COG2854	intermembrane phospholipid transfer
VCLMA_RS11715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
VCLMA_RS11720	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
VCLMA_RS11725	COG1127	ABC transporter
VCLMA_RS11740	COG0517	IMP dehydrogenase activity
VCLMA_RS11740	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
VCLMA_RS11755	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
VCLMA_RS11760	COG1137	ATPase activity
VCLMA_RS11770	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
VCLMA_RS11775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCLMA_RS11785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
VCLMA_RS11790	COG2239	Acts as a magnesium transporter
VCLMA_RS11795	COG0312	modulator of DNA gyrase
VCLMA_RS11800	COG3028	Belongs to the UPF0307 family
VCLMA_RS11805	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
VCLMA_RS11810	COG1178	ABC-type Fe3 transport system permease component
VCLMA_RS11820	COG0163	prenyltransferase activity
VCLMA_RS11825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
VCLMA_RS11840	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
VCLMA_RS11845	COG2105	PFAM AIG2 family protein
VCLMA_RS11855	COG0729	surface antigen
VCLMA_RS11860	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
VCLMA_RS11865	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
VCLMA_RS11880	COG1136	(ABC) transporter
VCLMA_RS11900	COG0529	Catalyzes the synthesis of activated sulfate
VCLMA_RS11905	COG2895	sulfate adenylyltransferase (ATP) activity
VCLMA_RS11910	COG0175	sulfate reduction
VCLMA_RS11915	COG1648	precorrin-2 dehydrogenase activity
VCLMA_RS11915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
VCLMA_RS11920	COG0737	Belongs to the 5'-nucleotidase family
VCLMA_RS11930	COG0513	Belongs to the DEAD box helicase family
VCLMA_RS11935	COG2153	protein acetylation
VCLMA_RS11940	COG0697	spore germination
VCLMA_RS11945	COG3061	Opacity-associated protein A
VCLMA_RS11945	COG3266	domain, Protein
VCLMA_RS11950	COG0545	Peptidyl-prolyl cis-trans isomerase
VCLMA_RS11960	COG0203	ribosomal protein L17
VCLMA_RS11965	COG0202	RNA polymerase activity
VCLMA_RS11970	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
VCLMA_RS11975	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
VCLMA_RS11980	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VCLMA_RS11985	COG0257	Belongs to the bacterial ribosomal protein bL36 family
VCLMA_RS11990	COG0201	protein transport
VCLMA_RS11995	COG0200	Binds to the 23S rRNA
VCLMA_RS12000	COG1841	ribosomal large subunit assembly
VCLMA_RS12005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
VCLMA_RS12010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
VCLMA_RS12020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
VCLMA_RS12025	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
VCLMA_RS12030	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VCLMA_RS12035	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
VCLMA_RS12040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
VCLMA_RS12045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
VCLMA_RS12050	COG0255	Belongs to the universal ribosomal protein uL29 family
VCLMA_RS12055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
VCLMA_RS12060	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
VCLMA_RS12065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
VCLMA_RS12070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
VCLMA_RS12075	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VCLMA_RS12080	COG0089	rRNA binding
VCLMA_RS12085	COG0088	Forms part of the polypeptide exit tunnel
VCLMA_RS12090	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
VCLMA_RS12095	COG0051	transcription antitermination factor activity, RNA binding
VCLMA_RS12100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
VCLMA_RS12105	COG0557	exoribonuclease II activity
VCLMA_RS12110	COG3083	sulfuric ester hydrolase activity
VCLMA_RS12115	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
VCLMA_RS12120	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
VCLMA_RS12130	COG1047	Peptidyl-prolyl cis-trans
VCLMA_RS12145	COG2249	NAD(P)H dehydrogenase (quinone) activity
VCLMA_RS12150	COG0488	(ABC) transporter
VCLMA_RS12160	COG0429	hydrolase of the alpha beta-hydrolase fold
VCLMA_RS12170	COG3954	Phosphoribulokinase
VCLMA_RS12195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
VCLMA_RS12205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
VCLMA_RS12220	COG0180	Tryptophanyl-tRNA synthetase
VCLMA_RS12225	COG0546	phosphoglycolate phosphatase activity
VCLMA_RS12230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
VCLMA_RS12235	COG0338	D12 class N6 adenine-specific DNA methyltransferase
VCLMA_RS12245	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
VCLMA_RS12250	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
VCLMA_RS12290	COG0678	peroxiredoxin activity
VCLMA_RS12290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
VCLMA_RS12295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
VCLMA_RS12305	COG0165	Argininosuccinate lyase
VCLMA_RS12310	COG0137	argininosuccinate synthase activity
VCLMA_RS12315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
VCLMA_RS12320	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
VCLMA_RS12325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
VCLMA_RS12330	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
VCLMA_RS12345	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
VCLMA_RS12350	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
VCLMA_RS12355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
VCLMA_RS12360	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
VCLMA_RS12365	COG1053	succinate dehydrogenase
VCLMA_RS12370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
VCLMA_RS12375	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
VCLMA_RS12385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
VCLMA_RS12390	COG1509	lysine 2,3-aminomutase activity
VCLMA_RS12400	COG0459	protein refolding
VCLMA_RS12405	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
VCLMA_RS12430	COG0149	triose-phosphate isomerase activity
VCLMA_RS12435	COG0534	Mate efflux family protein
VCLMA_RS12440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
VCLMA_RS12445	COG1575	Belongs to the MenA family. Type 1 subfamily
VCLMA_RS12450	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
VCLMA_RS12455	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
VCLMA_RS12465	COG1609	Transcriptional regulator
VCLMA_RS12470	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
VCLMA_RS12475	COG0254	rRNA binding
VCLMA_RS12485	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
VCLMA_RS12490	COG0626	cystathionine gamma-synthase activity
VCLMA_RS12495	COG0527	aspartate kinase activity
VCLMA_RS12495	COG0460	homoserine dehydrogenase
VCLMA_RS12500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
VCLMA_RS12505	COG3074	FtsZ-dependent cytokinesis
VCLMA_RS12510	COG1494	fructose-1,6-bisphosphatase
VCLMA_RS12515	COG0205	6-phosphofructokinase activity
VCLMA_RS12520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
VCLMA_RS12530	COG0745	RESPONSE REGULATOR receiver
VCLMA_RS12535	COG2205	protein histidine kinase activity
VCLMA_RS12545	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
VCLMA_RS12550	COG3030	protein affecting phage T7 exclusion by the F plasmid
VCLMA_RS12555	COG3706	GGDEF domain
VCLMA_RS12560	COG1027	Aspartate ammonia-lyase
VCLMA_RS12565	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
VCLMA_RS12580	COG4232	protein-disulfide reductase activity
VCLMA_RS12605	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
VCLMA_RS12610	COG0194	GDP metabolic process
VCLMA_RS12615	COG1758	RNA polymerase activity
VCLMA_RS12620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
VCLMA_RS12625	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
VCLMA_RS12630	COG2233	PERMEase
VCLMA_RS12645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
VCLMA_RS12650	COG2183	response to ionizing radiation
VCLMA_RS12660	COG0596	Alpha beta hydrolase
VCLMA_RS12675	COG0494	nUDIX hydrolase
VCLMA_RS12680	COG1218	3'(2'),5'-bisphosphate nucleotidase
VCLMA_RS12690	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCLMA_RS12695	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
VCLMA_RS12700	COG3156	type II secretion system protein K
VCLMA_RS12705	COG4795	General secretion pathway protein
VCLMA_RS12710	COG2165	general secretion pathway protein
VCLMA_RS12715	COG2165	general secretion pathway protein
VCLMA_RS12720	COG2165	general secretion pathway protein
VCLMA_RS12725	COG1459	type II secretion system
VCLMA_RS12740	COG3031	protein transport across the cell outer membrane
VCLMA_RS12745	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
VCLMA_RS12750	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
VCLMA_RS12755	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
VCLMA_RS12765	COG0456	acetyltransferase
VCLMA_RS12770	COG1490	D-aminoacyl-tRNA deacylase activity
VCLMA_RS12775	COG1295	ribonuclease BN
VCLMA_RS12785	COG1217	gtp-binding protein TYPA
VCLMA_RS12795	COG0174	glutamine synthetase
VCLMA_RS12805	COG3852	Histidine kinase
VCLMA_RS12815	COG5001	Diguanylate cyclase
VCLMA_RS12815	COG3300	MHYT domain
VCLMA_RS12820	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
VCLMA_RS12900	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
VCLMA_RS12905	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
VCLMA_RS12910	COG1739	Uncharacterized protein family UPF0029
VCLMA_RS12915	COG1024	Enoyl-CoA hydratase
VCLMA_RS12915	COG1250	3-hydroxyacyl-CoA dehydrogenase
VCLMA_RS12925	COG0583	DNA-binding transcription factor activity
VCLMA_RS12930	COG2814	Major facilitator Superfamily
VCLMA_RS12940	COG0355	proton-transporting ATP synthase activity, rotational mechanism
VCLMA_RS12945	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
VCLMA_RS12950	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
VCLMA_RS12955	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
VCLMA_RS12960	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
VCLMA_RS12965	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
VCLMA_RS12975	COG0356	it plays a direct role in the translocation of protons across the membrane
VCLMA_RS12980	COG3312	ion transport
VCLMA_RS12985	COG1475	DNA binding
VCLMA_RS12990	COG1192	Involved in chromosome partitioning
VCLMA_RS12995	COG0357	Ribosomal RNA small subunit methyltransferase G
VCLMA_RS13000	COG0445	tRNA wobble uridine modification
VCLMA_RS13015	COG0706	membrane insertase activity
VCLMA_RS13045	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
VCLMA_RS13125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
VCLMA_RS13245	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
VCLMA_RS13315	COG2081	HI0933 family
VCLMA_RS13820	COG1132	(ABC) transporter
VCLMA_RS13835	COG1120	ATPase activity
VCLMA_RS14210	COG1982	Orn Lys Arg decarboxylase major
VCLMA_RS14250	COG1609	Transcriptional regulator
VCLMA_RS14300	COG2814	Major facilitator Superfamily
VCLMA_RS14535	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
VCLMA_RS14595	COG0085	RNA polymerase activity
VCLMA_RS14615	COG0085	RNA polymerase activity
VCLMA_RS14630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
VCLMA_RS15100	COG2235	arginine
VCLMA_RS15175	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VCLMA_RS15265	COG0741	lytic transglycosylase activity
VCLMA_RS15690	COG3107	peptidoglycan biosynthetic process
VCLMA_RS15740	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
VCLMA_RS15750	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VCLMA_RS15790	COG1643	Atp-dependent helicase
VCLMA_RS16395	COG0826	peptidase U32
VCLMA_RS16400	COG0826	peptidase U32
VCLMA_RS16615	COG1160	GTP binding
VCLMA_RS16890	COG0443	Heat shock 70 kDa protein
VCLMA_RS16935	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
VCLMA_RS16975	COG0047	phosphoribosylformylglycinamidine synthase activity
VCLMA_RS16975	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
VCLMA_RS16995	COG0442	prolyl-tRNA aminoacylation
VCLMA_RS17265	COG0768	penicillin binding
VCLMA_RS17290	COG0495	leucyl-tRNA aminoacylation
VCLMA_RS17430	COG0248	Ppx GppA phosphatase
VCLMA_RS17435	COG3107	peptidoglycan biosynthetic process