locus-tag	class	description
GTF74_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GTF74_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GTF74_RS00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GTF74_RS00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GTF74_RS00030	ENOG4108ZNX	Heat shock protein
GTF74_RS00035	ENOG4105JKW	Valine--pyruvate aminotransferase
GTF74_RS00040	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GTF74_RS00045	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
GTF74_RS00060	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GTF74_RS00070	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
GTF74_RS00075	ENOG4105C7B	Threonine dehydratase
GTF74_RS00080	ENOG4105C01	Dihydroxy-acid dehydratase
GTF74_RS00085	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GTF74_RS00100	ENOG4105C0P	Mg chelatase subunit ChlI
GTF74_RS00105	ENOG4106HNH	Acyl-transferase
GTF74_RS00110	ENOG4108Z33	Thiol disulfide Interchange Protein
GTF74_RS00115	ENOG4105E27	serine threonine protein kinase
GTF74_RS00125	ENOG4105PC1	Conserved Protein
GTF74_RS00130	ENOG4108N23	SpoOM-related protein
GTF74_RS00135	ENOG4108UT2	hemolysin iii
GTF74_RS00145	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GTF74_RS00150	ENOG4105C1A	potassium transporter peripheral membrane
GTF74_RS00155	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GTF74_RS00160	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GTF74_RS00165	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GTF74_RS00170	ENOG4108WZM	domain protein
GTF74_RS00175	ENOG4105C79	DNA protecting protein DprA
GTF74_RS00180	ENOG4108RPN	Protein smg homolog
GTF74_RS00185	ENOG4108WI1	Dna topoisomerase
GTF74_RS00190	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GTF74_RS00195	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GTF74_RS00200	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GTF74_RS00205	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GTF74_RS00210	ENOG4105E2X	shikimate dehydrogenase
GTF74_RS00220	ENOG4108Z0R	Transferase
GTF74_RS00260	ENOG4105WMR	Protein CrcB homolog
GTF74_RS00265	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GTF74_RS00275	ENOG4105D06	uba thif-type nad fad binding protein
GTF74_RS00280	ENOG4105WHD	thiamine biosynthesis protein ThiS
GTF74_RS00285	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GTF74_RS00290	ENOG4105D41	biosynthesis protein thiH
GTF74_RS00295	ENOG4105DC7	peptidase M24
GTF74_RS00295	ENOG4105DC7	peptidase M24
GTF74_RS00300	ENOG4105G2Y	Transcriptional regulator
GTF74_RS00305	ENOG4105CNH	Multidrug resistance protein MdtL
GTF74_RS00315	ENOG4108VVK	transcriptional Regulator, AsnC
GTF74_RS00320	ENOG4105BZU	Histidine kinase
GTF74_RS00335	ENOG4105EMK	carboxylate amino acid amine transporter
GTF74_RS00340	ENOG4108M6U	Universal stress protein A
GTF74_RS00345	ENOG41090A1	ferritin
GTF74_RS00350	ENOG4108V6B	universal stress protein B
GTF74_RS00355	ENOG4105CBX	hi0933 family
GTF74_RS00365	ENOG4105CGY	Dna recombination protein
GTF74_RS00370	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GTF74_RS00375	ENOG4105JC1	sterol-binding domain protein
GTF74_RS00385	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GTF74_RS00390	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GTF74_RS00395	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GTF74_RS00400	ENOG4105CA0	peroxidase
GTF74_RS00405	ENOG4107R73	Mate efflux family protein
GTF74_RS00415	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GTF74_RS00425	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GTF74_RS00430	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
GTF74_RS00435	ENOG4105X6C	Flagellar basal body-associated protein FliL
GTF74_RS00440	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS00450	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GTF74_RS00455	ENOG4105F8V	Hydrolase, tatD family
GTF74_RS00460	ENOG4105D52	delta-aminolevulinic acid dehydratase
GTF74_RS00470	ENOG4105C2M	dna polymerase I
GTF74_RS00480	ENOG4106RE7	Cytochrome
GTF74_RS00490	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
GTF74_RS00495	ENOG4105XCT	Protein of unknown function (DUF2489)
GTF74_RS00500	ENOG4105D4P	Coproporphyrinogen iii oxidase
GTF74_RS00505	ENOG410601J	HemY protein
GTF74_RS00510	ENOG4105ECF	c-methyltransferase
GTF74_RS00520	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GTF74_RS00525	ENOG4107T0K	Adenylate cyclase
GTF74_RS00530	ENOG4105XQ6	frataxin-like protein
GTF74_RS00540	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GTF74_RS00545	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GTF74_RS00550	ENOG4105CT0	Protein of unknown function, DUF484
GTF74_RS00555	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GTF74_RS00560	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
GTF74_RS00565	ENOG4105BZU	Histidine kinase
GTF74_RS00580	ENOG4105DQF	Hydrolase
GTF74_RS00585	ENOG4108EUD	Lysophospholipase
GTF74_RS00590	ENOG410829K	Lysine exporter protein (Lyse ygga)
GTF74_RS00595	ENOG4105D58	Diguanylate phosphodiesterase
GTF74_RS00600	ENOG4108RMU	ferritin dps family protein
GTF74_RS00630	ENOG4106H78	methyltransferase
GTF74_RS00635	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GTF74_RS00640	ENOG4105CAK	Cell division ATP-binding protein ftsE
GTF74_RS00645	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GTF74_RS00650	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GTF74_RS00655	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
GTF74_RS00670	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
GTF74_RS00675	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GTF74_RS00680	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GTF74_RS00685	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GTF74_RS00755	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GTF74_RS00760	ENOG4105BZU	Histidine kinase
GTF74_RS00765	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF74_RS00770	ENOG4105CUX	Signal transduction histidine kinase
GTF74_RS00780	ENOG4105C5F	glutamine synthetase
GTF74_RS00790	ENOG4105CI3	gtp-binding protein typa
GTF74_RS00800	ENOG4107S2Z	UPF0761 membrane protein
GTF74_RS00805	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GTF74_RS00810	ENOG4105SUU	thioesterase domain
GTF74_RS00820	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GTF74_RS00825	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GTF74_RS00830	ENOG4105VEJ	Heat shock protein
GTF74_RS00835	ENOG4108XKW	General secretion pathway protein C
GTF74_RS00845	ENOG4107QHF	type ii secretion system protein e
GTF74_RS00850	ENOG4105D7Q	type ii secretion system
GTF74_RS00855	ENOG4108VAU	general secretion pathway protein G
GTF74_RS00860	ENOG4105VWV	general secretion pathway protein h
GTF74_RS00865	ENOG4105X5Z	General secretion pathway protein I
GTF74_RS00870	ENOG4108WWZ	General secretion pathway protein J
GTF74_RS00875	ENOG4108RTD	type II secretion system protein K
GTF74_RS00880	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
GTF74_RS00885	ENOG4105U1E	general secretion pathway protein M
GTF74_RS00890	ENOG4105PIC	general secretion pathway protein N
GTF74_RS00895	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GTF74_RS00900	ENOG4107RK2	ADP-ribose diphosphatase NudE
GTF74_RS00910	ENOG4105MJ2	Competence protein
GTF74_RS00920	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GTF74_RS00930	ENOG4105BZM	domain protein
GTF74_RS00935	ENOG4108RRZ	Transcription elongation factor GreB
GTF74_RS00945	ENOG4105E0F	Histidine kinase
GTF74_RS00950	ENOG4105C2W	permease
GTF74_RS00955	ENOG4105CB5	ATP-dependent DNA helicase recG
GTF74_RS00960	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GTF74_RS00965	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GTF74_RS00970	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GTF74_RS00975	ENOG4105EX9	Membrane
GTF74_RS00980	ENOG4107QN1	sodium solute
GTF74_RS01000	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GTF74_RS01010	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GTF74_RS01015	ENOG4108IJ0	Aspartate ammonia-lyase
GTF74_RS01020	ENOG4105BZU	Histidine kinase
GTF74_RS01025	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
GTF74_RS01030	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GTF74_RS01040	ENOG4105E0F	Histidine kinase
GTF74_RS01045	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GTF74_RS01055	ENOG41076HS	cation diffusion facilitator family transporter
GTF74_RS01060	ENOG4105CTQ	phosphohexokinase
GTF74_RS01065	ENOG4105CBT	Fructose-1,6-bisphosphatase
GTF74_RS01070	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
GTF74_RS01075	ENOG4105SYT	Methylenetetrahydrofolate reductase
GTF74_RS01080	ENOG4105CFH	Aspartokinase
GTF74_RS01085	ENOG4105C28	cystathionine
GTF74_RS01090	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
GTF74_RS01095	ENOG4105C6K	Malic enzyme
GTF74_RS01100	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GTF74_RS01105	ENOG4105C25	Primosomal protein n'
GTF74_RS01110	ENOG4105ETE	Transcriptional regulator (LacI family
GTF74_RS01115	ENOG41063M6	Cell Division Protein
GTF74_RS01120	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GTF74_RS01125	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GTF74_RS01130	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GTF74_RS01135	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GTF74_RS01145	ENOG4105CP7	Triose-phosphate isomerase
GTF74_RS01170	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GTF74_RS01175	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GTF74_RS01185	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GTF74_RS01190	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GTF74_RS01200	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GTF74_RS01205	ENOG4105E33	succinate dehydrogenase
GTF74_RS01215	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
GTF74_RS01220	ENOG4107YZP	Rhodanese domain protein
GTF74_RS01225	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GTF74_RS01230	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GTF74_RS01235	ENOG4105D7W	serine acetyltransferase
GTF74_RS01245	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GTF74_RS01250	ENOG4105CWC	Acetylornithine deacetylase
GTF74_RS01255	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GTF74_RS01260	ENOG4105CAS	nag kinase
GTF74_RS01265	ENOG4105CDH	Citrulline--aspartate ligase
GTF74_RS01270	ENOG4105CH7	arginosuccinase
GTF74_RS01280	ENOG4107QN2	dihydrolipoyl dehydrogenase
GTF74_RS01285	ENOG4105EHV	domain protein
GTF74_RS01295	ENOG4108JQC	penicillin-binding protein 1A
GTF74_RS01320	ENOG4105E4G	Type IV pilus
GTF74_RS01325	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GTF74_RS01330	ENOG4105D49	3-dehydroquinate synthase
GTF74_RS01340	ENOG4105DFE	Dna adenine methylase
GTF74_RS01345	ENOG4105DJV	ribulose-phosphate 3-epimerase
GTF74_RS01350	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GTF74_RS01355	ENOG4105C31	Tryptophanyl-tRNA synthetase
GTF74_RS01370	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GTF74_RS01375	ENOG4105DDQ	anthranilate synthase
GTF74_RS01380	ENOG4105C8Y	Acetylornithine aminotransferase
GTF74_RS01390	ENOG4105C26	Dehydrogenase
GTF74_RS01400	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GTF74_RS01405	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
GTF74_RS01415	ENOG4105DNZ	Alpha Beta Hydrolase
GTF74_RS01425	ENOG4105C5H	ABC transporter
GTF74_RS01430	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GTF74_RS01445	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GTF74_RS01450	ENOG4105D44	asparaginase
GTF74_RS01460	ENOG4108UV7	flagellar protein motX
GTF74_RS01465	ENOG4105E68	Sulfatase
GTF74_RS01470	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GTF74_RS01475	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GTF74_RS01480	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GTF74_RS01485	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GTF74_RS01490	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GTF74_RS01495	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GTF74_RS01500	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GTF74_RS01505	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GTF74_RS01510	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GTF74_RS01515	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GTF74_RS01520	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GTF74_RS01525	ENOG41083MP	50s ribosomal protein l29
GTF74_RS01530	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GTF74_RS01535	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GTF74_RS01540	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GTF74_RS01545	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GTF74_RS01550	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GTF74_RS01555	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GTF74_RS01565	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GTF74_RS01570	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GTF74_RS01575	ENOG4105VPB	50S ribosomal protein L30
GTF74_RS01585	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GTF74_RS01595	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GTF74_RS01600	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GTF74_RS01605	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GTF74_RS01610	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GTF74_RS01615	ENOG4108ZT0	50S ribosomal protein l17
GTF74_RS01625	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GTF74_RS01630	ENOG4108UBT	opacity-associated protein
GTF74_RS01635	ENOG4108SXK	Transporter Drug Metabolite Exporter family
GTF74_RS01640	ENOG4107YB6	acetyltransferase, (GNAT) family
GTF74_RS01645	ENOG4105C1J	atp-dependent rna helicase
GTF74_RS01655	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
GTF74_RS01660	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GTF74_RS01675	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
GTF74_RS01695	ENOG4105C19	ABC transporter
GTF74_RS01710	ENOG4108UUE	Transcriptional regulator
GTF74_RS01715	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GTF74_RS01720	ENOG4105CFU	surface antigen
GTF74_RS01730	ENOG41066HZ	AIG2-like family
GTF74_RS01735	ENOG4105F0N	pyrophosphate phospho-hydrolase
GTF74_RS01745	ENOG4105DFU	Cell wall formation (By similarity)
GTF74_RS01750	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GTF74_RS01760	ENOG4106SMU	thiamine transporter membrane protein
GTF74_RS01765	ENOG4107T0D	ABC, transporter
GTF74_RS01770	ENOG4105N42	UPF0307 protein
GTF74_RS01775	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GTF74_RS01780	ENOG4105CJW	magnesium transporter
GTF74_RS01785	ENOG41080Z8	PHOSPHOCARRIER protein
GTF74_RS01790	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GTF74_RS01795	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GTF74_RS01800	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GTF74_RS01805	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GTF74_RS01810	ENOG4108IUZ	ABC transporter
GTF74_RS01815	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
GTF74_RS01825	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
GTF74_RS01830	ENOG4105C2X	Arabinose 5-phosphate isomerase
GTF74_RS01840	ENOG4105DHJ	ABC, transporter
GTF74_RS01845	ENOG4105CY3	ABC transporter, permease
GTF74_RS01850	ENOG4107PE3	Mammalian cell entry related domain protein
GTF74_RS01855	ENOG4105E3I	toluene tolerance
GTF74_RS01865	ENOG4105VFK	BolA family
GTF74_RS01870	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GTF74_RS01875	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GTF74_RS01880	ENOG4105KME	endoribonuclease L-psp
GTF74_RS01890	ENOG4105CXT	aspartate transcarbamylase
GTF74_RS01900	ENOG4108IAB	Phoh family
GTF74_RS01910	ENOG4105D3G	Pseudouridine synthase
GTF74_RS01915	ENOG4105C5I	Dehydrogenase
GTF74_RS01920	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GTF74_RS01925	ENOG4105MYG	DNA polymerase iii, chi subunit
GTF74_RS01930	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GTF74_RS01935	ENOG4108M8S	permease YjgP YjgQ family protein
GTF74_RS01940	ENOG4108K5H	permease YjgP YjgQ family protein
GTF74_RS01955	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GTF74_RS02000	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GTF74_RS02005	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GTF74_RS02010	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GTF74_RS02035	ENOG41064T2	transcriptional regulator, lysR family
GTF74_RS02040	ENOG4108IQE	Amp-dependent synthetase and ligase
GTF74_RS02045	ENOG4105C7K	acetolactate synthase
GTF74_RS02050	ENOG4108ZP8	Acetolactate synthase small subunit
GTF74_RS02055	ENOG4108JQ1	Dehydrogenase
GTF74_RS02060	ENOG4105E66	phosphoriboisomerase A
GTF74_RS02065	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GTF74_RS02075	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GTF74_RS02085	ENOG4105D0A	hydroxylase
GTF74_RS02090	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GTF74_RS02105	ENOG4105Y75	tpr repeat protein
GTF74_RS02115	ENOG4108IYU	L-aspartate oxidase
GTF74_RS02120	ENOG4105EMN	RNA polymerase sigma factor
GTF74_RS02135	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
GTF74_RS02140	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GTF74_RS02145	ENOG4105C3F	Signal peptidase i
GTF74_RS02155	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GTF74_RS02160	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
GTF74_RS02165	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GTF74_RS02185	ENOG4108K0B	C-di-gmp phosphodiesterase
GTF74_RS02190	ENOG4105BZU	Histidine kinase
GTF74_RS02200	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GTF74_RS02205	ENOG4105DXN	mazG family
GTF74_RS02210	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GTF74_RS02215	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GTF74_RS02235	ENOG4106MWK	domain protein
GTF74_RS02240	ENOG4105CJ3	phosphate transporter
GTF74_RS02245	ENOG4107IX6	phosphate transport regulator
GTF74_RS02250	ENOG4105I7R	Adenylate cyclase
GTF74_RS02255	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS02260	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GTF74_RS02270	ENOG4105DFG	type I secretion outer membrane protein
GTF74_RS02275	ENOG41087AY	ADP-Ribose pyrophosphatase
GTF74_RS02280	ENOG4108SX3	cytoplasmic protein
GTF74_RS02285	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GTF74_RS02290	ENOG4105IPS	esterase
GTF74_RS02295	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GTF74_RS02300	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GTF74_RS02310	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
GTF74_RS02315	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GTF74_RS02320	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GTF74_RS02325	ENOG4105D7Q	type ii secretion system
GTF74_RS02330	ENOG4107QHF	type ii secretion system protein e
GTF74_RS02340	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GTF74_RS02350	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
GTF74_RS02355	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GTF74_RS02360	ENOG4105T95	Thiol disulfide interChange protein
GTF74_RS02365	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GTF74_RS02370	ENOG4105CGH	5'-nucleotidase
GTF74_RS02375	ENOG41073TP	transcriptional regulator
GTF74_RS02380	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GTF74_RS02385	ENOG4107QSN	dihydrolipoamide acetyltransferase
GTF74_RS02390	ENOG4107QN2	dihydrolipoyl dehydrogenase
GTF74_RS02405	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GTF74_RS02410	ENOG4105CJN	penicillin-binding protein
GTF74_RS02415	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GTF74_RS02420	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GTF74_RS02430	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GTF74_RS02445	ENOG4105DFU	Cell wall formation (By similarity)
GTF74_RS02450	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GTF74_RS02455	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GTF74_RS02460	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GTF74_RS02465	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GTF74_RS02475	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GTF74_RS02480	ENOG4105M6F	mutator MutT protein
GTF74_RS02485	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GTF74_RS02495	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GTF74_RS02500	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GTF74_RS02520	ENOG4107RRE	RNA-directed DNA polymerase
GTF74_RS02525	ENOG4105EJ9	Membrane
GTF74_RS02530	ENOG4105VP0	transcriptional regulator, lysR family
GTF74_RS02535	ENOG4105EN6	Membrane
GTF74_RS02540	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GTF74_RS02550	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GTF74_RS02560	ENOG4105BZ8	glutamate synthase
GTF74_RS02565	ENOG4105CBC	glutamate synthase
GTF74_RS02580	ENOG4105N5T	Radical SAM Protein
GTF74_RS02590	ENOG4105BZU	Histidine kinase
GTF74_RS02595	ENOG41065U4	response regulator
GTF74_RS02605	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GTF74_RS02630	ENOG4105D98	threonine synthase
GTF74_RS02635	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
GTF74_RS02640	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GTF74_RS02645	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GTF74_RS02660	ENOG4105BZG	amino acid carrier protein
GTF74_RS02665	ENOG4105D1Q	UPF0246 protein
GTF74_RS02675	ENOG4105EYA	deoxyribonuclease
GTF74_RS02680	ENOG4105D9N	nucleoside
GTF74_RS02690	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GTF74_RS02695	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GTF74_RS02700	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GTF74_RS02705	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GTF74_RS02715	ENOG4105EAC	phosphoserine phosphatase
GTF74_RS02725	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GTF74_RS02730	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GTF74_RS02735	ENOG4108IQE	Amp-dependent synthetase and ligase
GTF74_RS02740	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GTF74_RS02750	ENOG4105CNT	hydrolase family 2
GTF74_RS02755	ENOG41060NJ	transcriptional regulator
GTF74_RS02760	ENOG4108Y51	tRNA-binding protein
GTF74_RS02775	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GTF74_RS02780	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
GTF74_RS02790	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
GTF74_RS02795	ENOG4105X2V	dna damage-inducible protein
GTF74_RS02810	ENOG4105DSY	exodeoxyribonuclease V, gamma
GTF74_RS02815	ENOG4107QKA	exodeoxyribonuclease V beta
GTF74_RS02820	ENOG4107QYX	exodeoxyribonuclease v alpha
GTF74_RS02840	ENOG4105CA3	membrane-bound lytic murein transglycosylase
GTF74_RS02845	ENOG4105CUZ	uba thif-type nad fad binding protein
GTF74_RS02850	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GTF74_RS02855	ENOG4105C9B	Cysteine desulfurase
GTF74_RS02860	ENOG4107S0N	DJ-1 family
GTF74_RS02865	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GTF74_RS02870	ENOG4105DRB	nucleoside-specific channel-forming protein
GTF74_RS02880	ENOG4105K6V	RNA polymerase
GTF74_RS02890	ENOG4105EYM	Major Facilitator superfamily
GTF74_RS02895	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GTF74_RS02905	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GTF74_RS02910	ENOG4105M85	Bola protein
GTF74_RS02915	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GTF74_RS02920	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GTF74_RS02925	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GTF74_RS02930	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GTF74_RS02935	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GTF74_RS02940	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
GTF74_RS02945	ENOG4105CJ2	(LipO)protein
GTF74_RS02965	ENOG4105BZU	Histidine kinase
GTF74_RS02970	ENOG4105C8J	)-transporter
GTF74_RS02980	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GTF74_RS02985	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GTF74_RS02990	ENOG4105CIN	aminoacyl-histidine dipeptidase
GTF74_RS02995	ENOG4105C7N	Xanthine uracil vitamin C permease
GTF74_RS03000	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GTF74_RS03005	ENOG4108DJV	Fermentation respiration switch protein
GTF74_RS03010	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
GTF74_RS03015	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GTF74_RS03020	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GTF74_RS03025	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GTF74_RS03030	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GTF74_RS03045	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GTF74_RS03050	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GTF74_RS03055	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GTF74_RS03060	ENOG4108ZAI	phosphatidylglycerophosphatase a
GTF74_RS03065	ENOG4108T8E	UPF0325 protein
GTF74_RS03070	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GTF74_RS03075	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GTF74_RS03080	ENOG4105CE9	30S ribosomal protein S2
GTF74_RS03085	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GTF74_RS03090	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GTF74_RS03095	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GTF74_RS03100	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GTF74_RS03105	ENOG4105KNE	Phosphatidate cytidylyltransferase
GTF74_RS03110	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GTF74_RS03115	ENOG4105DZP	Membrane-associated zinc metalloprotease
GTF74_RS03125	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
GTF74_RS03130	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GTF74_RS03135	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GTF74_RS03140	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GTF74_RS03145	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GTF74_RS03150	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GTF74_RS03155	ENOG4105C0B	DNA polymerase III (alpha subunit)
GTF74_RS03160	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GTF74_RS03165	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GTF74_RS03170	ENOG4105N7H	Cytochrome
GTF74_RS03175	ENOG4105PY6	Phenolic acid decarboxylase
GTF74_RS03180	ENOG4108YZA	Nitrogen regulatory protein pii
GTF74_RS03185	ENOG4107NA1	Endonuclease Exonuclease phosphatase
GTF74_RS03190	ENOG4105E9H	Lytic Murein transglycosylase
GTF74_RS03195	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GTF74_RS03200	ENOG4105D1A	Methyltransferase
GTF74_RS03205	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GTF74_RS03210	ENOG4107RZZ	dna polymerase iii epsilon subunit
GTF74_RS03220	ENOG4107QPN	acyl-Coa dehydrogenase
GTF74_RS03225	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GTF74_RS03230	ENOG4105E7A	Glutamine amidotransferase
GTF74_RS03235	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GTF74_RS03240	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GTF74_RS03245	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GTF74_RS03250	ENOG4105BZU	Histidine kinase
GTF74_RS03255	ENOG4105FE9	pseudouridine synthase
GTF74_RS03260	ENOG4108DG9	Smr protein MutS2
GTF74_RS03275	ENOG4105MBR	gumn family
GTF74_RS03280	ENOG4105E2D	ec 3.2.1.52
GTF74_RS03290	ENOG4105C59	p-type ATPase
GTF74_RS03295	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GTF74_RS03300	ENOG4105UYK	outer membrane protein a
GTF74_RS03310	ENOG4107RBR	Receptor
GTF74_RS03315	ENOG4105Q26	Siderophore-interacting protein
GTF74_RS03320	ENOG4105C0W	non-ribosomal peptide synthetase
GTF74_RS03355	ENOG4107R88	Chemotaxis protein (CheV)
GTF74_RS03360	ENOG4105BZU	Histidine kinase
GTF74_RS03365	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GTF74_RS03370	ENOG4108ZC9	flagellar basal-body rod protein flgc
GTF74_RS03375	ENOG4105W00	Flagellar hook capping protein
GTF74_RS03380	ENOG4105BZE	flagellar hook protein, FlgE
GTF74_RS03385	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GTF74_RS03390	ENOG4105CGA	flagellar basal-body rod protein FlgG
GTF74_RS03395	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GTF74_RS03400	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GTF74_RS03405	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GTF74_RS03420	ENOG4105I03	Flagellin
GTF74_RS03425	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GTF74_RS03445	ENOG4105MEH	
GTF74_RS03520	ENOG4105ED4	portal protein
GTF74_RS03645	ENOG4105I03	Flagellin
GTF74_RS03730	ENOG4105C3G	gtp-binding protein
GTF74_RS03735	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GTF74_RS03740	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GTF74_RS03745	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GTF74_RS03750	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
GTF74_RS03755	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GTF74_RS03760	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GTF74_RS03765	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GTF74_RS03770	ENOG4108YY7	Invasion gene expression up-regulator SirB
GTF74_RS03775	ENOG41063JG	Transcriptional regulator
GTF74_RS03780	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GTF74_RS03785	ENOG4105CGH	5'-nucleotidase
GTF74_RS03790	ENOG4108Z66	YbaK ebsC protein
GTF74_RS03795	ENOG4105C2W	permease
GTF74_RS03810	ENOG4105CS1	NAD(P)H quinone oxidoreductase
GTF74_RS03815	ENOG4105K89	arsenate reductase
GTF74_RS03820	ENOG4105ERG	peptidase m48, ste24p
GTF74_RS03835	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS03840	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GTF74_RS03855	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GTF74_RS03875	ENOG4105KUZ	arsenate reductase
GTF74_RS03890	ENOG4105QZU	Inner membrane protein YfeZ
GTF74_RS03895	ENOG4105EZR	dyp-type peroxidase family protein
GTF74_RS03900	ENOG4105I03	Flagellin
GTF74_RS03905	ENOG4105I03	Flagellin
GTF74_RS03910	ENOG4105I03	Flagellin
GTF74_RS03915	ENOG41063QE	flagellar protein FlaG
GTF74_RS03920	ENOG4107W9T	flagellar hook-associated
GTF74_RS03930	ENOG4105MQ3	flagellar protein FliS
GTF74_RS03940	ENOG4105BZU	Histidine kinase
GTF74_RS03950	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GTF74_RS03955	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GTF74_RS03960	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GTF74_RS03965	ENOG4105W2B	Flagellar assembly protein
GTF74_RS03970	ENOG4108JIR	Flagellum-specific ATP synthase
GTF74_RS03990	ENOG4105X6C	Flagellar basal body-associated protein FliL
GTF74_RS03995	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GTF74_RS04000	ENOG4105DD5	Flagellar motor switch protein
GTF74_RS04005	ENOG4105VTB	flagellar biosynthesis protein fliO
GTF74_RS04010	ENOG4105CN7	Flagellar biosynthetic protein FliP
GTF74_RS04015	ENOG4105VS8	Flagellar biosynthetic protein fliq
GTF74_RS04020	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GTF74_RS04025	ENOG4105D00	flagellar biosynthetic protein flhB
GTF74_RS04030	ENOG4108DG9	Smr protein MutS2
GTF74_RS04035	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GTF74_RS04040	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GTF74_RS04045	ENOG4105EN6	Membrane
GTF74_RS04050	ENOG4108BPE	-transporting atpase
GTF74_RS04055	ENOG4105MH2	YfcL protein
GTF74_RS04060	ENOG4105Q8W	reductase
GTF74_RS04070	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GTF74_RS04075	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GTF74_RS04080	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GTF74_RS04085	ENOG41090R7	Ferric uptake
GTF74_RS04095	ENOG4105CMU	LysR family (Transcriptional regulator
GTF74_RS04100	ENOG4105VAW	lrga family
GTF74_RS04105	ENOG41067MG	lrgb family
GTF74_RS04110	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GTF74_RS04120	ENOG4105EV9	Alpha Beta Hydrolase
GTF74_RS04125	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
GTF74_RS04130	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
GTF74_RS04140	ENOG4107QNR	UPF0135 protein
GTF74_RS04145	ENOG4105BZN	citrate synthase
GTF74_RS04150	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GTF74_RS04155	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GTF74_RS04160	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GTF74_RS04165	ENOG4105E33	succinate dehydrogenase
GTF74_RS04170	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GTF74_RS04175	ENOG4105C7S	Dehydrogenase
GTF74_RS04180	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GTF74_RS04185	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GTF74_RS04190	ENOG4105FAV	ABC, transporter
GTF74_RS04195	ENOG4105FDK	ABC transporter
GTF74_RS04200	ENOG4105NXV	High-affinity zinc uptake system protein
GTF74_RS04205	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
GTF74_RS04210	ENOG4105XFK	Ferrous iron transport protein A
GTF74_RS04230	ENOG4105C75	arginyL-tRNA synthetase
GTF74_RS04240	ENOG4108JQM	Insulinase (Peptidase family M16)
GTF74_RS04245	ENOG4108BY2	phosphohistidine phosphatase
GTF74_RS04250	ENOG4105D7B	Flagellar biosynthesis protein flha
GTF74_RS04255	ENOG4105FZW	flagellar biosynthesis regulator FlhF
GTF74_RS04265	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GTF74_RS04275	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
GTF74_RS04285	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GTF74_RS04290	ENOG4107QJE	Chromosome Partitioning Protein
GTF74_RS04300	ENOG4108V3W	Chemotaxis protein, CheW
GTF74_RS04310	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
GTF74_RS04315	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
GTF74_RS04320	ENOG41060IM	Heme exporter protein
GTF74_RS04325	ENOG41067VX	Heme exporter protein
GTF74_RS04330	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
GTF74_RS04335	ENOG4105DA4	cytochrome c-type biogenesis protein
GTF74_RS04340	ENOG4107QX9	Thiol disulfide interChange protein
GTF74_RS04345	ENOG4105KWW	Biogenesis protein
GTF74_RS04355	ENOG410903C	(LipO)protein
GTF74_RS04370	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GTF74_RS04375	ENOG4105M2J	Glutaredoxin
GTF74_RS04385	ENOG4105DGU	Histone deacetylase
GTF74_RS04400	ENOG4105E68	Sulfatase
GTF74_RS04405	ENOG4105YDX	UPF0352 protein
GTF74_RS04410	ENOG4106V8H	Nucleoid-associated protein
GTF74_RS04420	ENOG4105DFD	Na H antiporter
GTF74_RS04425	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GTF74_RS04430	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GTF74_RS04435	ENOG4105C0A	alcohol dehydrogenase
GTF74_RS04445	ENOG4105CHH	sulfate transporter
GTF74_RS04450	ENOG4105C03	ribonuclease
GTF74_RS04455	ENOG4105EI2	Pseudouridine synthase
GTF74_RS04460	ENOG4108UHJ	MAF-like protein
GTF74_RS04465	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GTF74_RS04470	ENOG4105VGS	50s ribosomal protein l32
GTF74_RS04475	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GTF74_RS04480	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GTF74_RS04485	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GTF74_RS04490	ENOG4105CHR	reductase
GTF74_RS04495	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GTF74_RS04505	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
GTF74_RS04510	ENOG4105HHA	aminodeoxychorismate lyase
GTF74_RS04515	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GTF74_RS04520	ENOG4107QRG	dna polymerase iii
GTF74_RS04525	ENOG4105F8V	Hydrolase, tatD family
GTF74_RS04530	ENOG4105CI1	PTS System
GTF74_RS04540	ENOG4105C8J	)-transporter
GTF74_RS04560	ENOG4105CA9	Pyruvate kinase
GTF74_RS04565	ENOG4105DAG	ROK family
GTF74_RS04585	ENOG4105DHI	Methyltransferase
GTF74_RS04595	ENOG4105DSB	aldose 1-epimerase
GTF74_RS04600	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GTF74_RS04605	ENOG4105E0X	reductase
GTF74_RS04615	ENOG4105VUT	cytoplasmic protein
GTF74_RS04620	ENOG4105HDK	L-asparaginase
GTF74_RS04625	ENOG4105D07	Signal peptide peptidase, SppA
GTF74_RS04630	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GTF74_RS04635	ENOG4105CIY	formyltetrahydrofolate deformylase
GTF74_RS04645	ENOG4105DVT	helicase
GTF74_RS04650	ENOG41072GX	Peptidase M22 Glycoprotease
GTF74_RS04665	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GTF74_RS04670	ENOG4105CEY	Amp-dependent synthetase and ligase
GTF74_RS04675	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
GTF74_RS04695	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GTF74_RS04700	ENOG4105DK2	UPF0207 protein
GTF74_RS04705	ENOG4105CHM	Aminotransferase
GTF74_RS04710	ENOG4105E4F	Isochorismate synthase
GTF74_RS04715	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GTF74_RS04720	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
GTF74_RS04725	ENOG4108IPT	Naphthoate synthase
GTF74_RS04735	ENOG4105CEY	Amp-dependent synthetase and ligase
GTF74_RS04740	ENOG4105DKK	Benzoate
GTF74_RS04745	ENOG4108JCI	Transcriptional regulator
GTF74_RS04750	ENOG4108N3W	hemolysin secretion protein
GTF74_RS04760	ENOG4107S74	Lysophospholipid transporter LplT
GTF74_RS04785	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GTF74_RS04790	ENOG4107QMS	site-determining protein
GTF74_RS04795	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GTF74_RS04800	ENOG4105VNG	YcgL domain-containing protein
GTF74_RS04805	ENOG4105CVE	Lytic murein transglycosylase
GTF74_RS04810	ENOG4105JQN	Transcriptional regulator
GTF74_RS04815	ENOG4105D9N	nucleoside
GTF74_RS04820	ENOG410662T	chitinase
GTF74_RS04825	ENOG4105CUW	cytochrome C-TYPE protein
GTF74_RS04830	ENOG4107QY8	reductase
GTF74_RS04840	ENOG4105JQN	Transcriptional regulator
GTF74_RS04855	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GTF74_RS04890	ENOG4108HPI	phosphatidate Cytidylyltransferase
GTF74_RS04900	ENOG4105BZU	Histidine kinase
GTF74_RS04910	ENOG4105CNG	UPF0061 protein
GTF74_RS04915	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GTF74_RS04920	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
GTF74_RS04925	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GTF74_RS04930	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF74_RS04945	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GTF74_RS04950	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GTF74_RS04955	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GTF74_RS04960	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GTF74_RS04965	ENOG4105K70	DNA-binding protein
GTF74_RS04970	ENOG4105EIN	peptidylprolyl cis-trans isomerase
GTF74_RS04975	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
GTF74_RS04980	ENOG4105CAT	Cytidine monophosphate kinase
GTF74_RS04985	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GTF74_RS04990	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GTF74_RS04995	ENOG4105Q4A	inner membrane protein yciS
GTF74_RS05000	ENOG4105CFV	Tetratricopeptide repeat protein
GTF74_RS05010	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
GTF74_RS05020	ENOG4107R11	Transcriptional regulator
GTF74_RS05030	ENOG4105DCF	alanine dehydrogenase
GTF74_RS05035	ENOG4105EW9	transcriptional regulator AsnC family
GTF74_RS05040	ENOG4105CNU	cell division protein FtsK
GTF74_RS05045	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GTF74_RS05050	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GTF74_RS05055	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
GTF74_RS05065	ENOG4108NVR	Methyl-accepting chemotaxis
GTF74_RS05070	ENOG4105K59	histidine triad (HIT) protein
GTF74_RS05095	ENOG4105D0Y	UPF0227 protein
GTF74_RS05100	ENOG4105CEP	NADH dehydrogenase
GTF74_RS05110	ENOG4106M3D	hemolysin
GTF74_RS05120	ENOG4108JA2	transcriptioN-repair coupling factor
GTF74_RS05130	ENOG4105D60	lipoprotein releasing system transmembrane protein
GTF74_RS05135	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GTF74_RS05140	ENOG4105D60	lipoprotein releasing system transmembrane protein
GTF74_RS05150	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
GTF74_RS05155	ENOG4105BZ1	(ABC) transporter
GTF74_RS05160	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GTF74_RS05165	ENOG4105W49	UPF0434 protein
GTF74_RS05170	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GTF74_RS05175	ENOG4105ED1	spovr family
GTF74_RS05180	ENOG4106AKX	UPF0229 protein
GTF74_RS05185	ENOG4105CYN	Serine protein kinase
GTF74_RS05190	ENOG4105XWI	UPF0304 protein
GTF74_RS05200	ENOG4105F1A	Pyruvate formate-lyase
GTF74_RS05205	ENOG4108N3W	hemolysin secretion protein
GTF74_RS05215	ENOG4105C6N	Formate acetyltransferase
GTF74_RS05225	ENOG4108JEH	abc transporter atp-binding protein
GTF74_RS05230	ENOG4105E89	ABC transporter
GTF74_RS05235	ENOG4105DSP	amino acid AbC transporter
GTF74_RS05240	ENOG4106YG3	ABC transporter
GTF74_RS05245	ENOG4105CGK	Exodeoxyribonuclease III
GTF74_RS05250	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS05255	ENOG4106428	Protein of unknown function (DUF2496)
GTF74_RS05260	ENOG4108URS	primosomal replication protein n''
GTF74_RS05265	ENOG4105EJ9	Membrane
GTF74_RS05270	ENOG4105DVT	helicase
GTF74_RS05275	ENOG4105ZU8	porin-like protein H
GTF74_RS05285	ENOG4105K5B	UPF0225 protein
GTF74_RS05290	ENOG4105D58	Diguanylate phosphodiesterase
GTF74_RS05295	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GTF74_RS05300	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GTF74_RS05305	ENOG4105C8N	cysteinyl-tRNA synthetase
GTF74_RS05310	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GTF74_RS05315	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GTF74_RS05325	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GTF74_RS05330	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GTF74_RS05340	ENOG4105KJB	cyd operon protein YbgE
GTF74_RS05345	ENOG4107YD3	Thioesterase
GTF74_RS05350	ENOG4105E02	MotA TolQ exbB proton channel
GTF74_RS05355	ENOG4105M8F	Biopolymer transport protein exbD tolR
GTF74_RS05365	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
GTF74_RS05370	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GTF74_RS05380	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GTF74_RS05390	ENOG4105BZU	Histidine kinase
GTF74_RS05395	ENOG4108RNS	Exports L-alanine (By similarity)
GTF74_RS05400	ENOG4105EIP	mannose-6-phosphate isomerase
GTF74_RS05405	ENOG4105DM4	PTS System
GTF74_RS05410	ENOG4106R3P	AraC family transcriptional regulator
GTF74_RS05420	ENOG4108YRF	PTS System
GTF74_RS05425	ENOG4105DM4	PTS System
GTF74_RS05430	ENOG4105DM4	PTS System
GTF74_RS05440	ENOG4105C26	Dehydrogenase
GTF74_RS05445	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
GTF74_RS05450	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GTF74_RS05460	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GTF74_RS05580	ENOG4108NYK	Tape measure protein
GTF74_RS05595	ENOG4108YGG	dna repair protein
GTF74_RS05605	ENOG4108478	ec 3.2.1.18
GTF74_RS05610	ENOG4105CE4	GlcNAc 6-P deacetylase
GTF74_RS05615	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
GTF74_RS05625	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
GTF74_RS05630	ENOG41069H7	transport system small permease component
GTF74_RS05635	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GTF74_RS05645	ENOG4105QEK	Transcriptional regulator
GTF74_RS05650	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
GTF74_RS05655	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
GTF74_RS05675	ENOG4105CVR	type I restriction-modification system
GTF74_RS05695	ENOG4105DZR	Type I site-specific deoxyribonuclease
GTF74_RS05715	ENOG4105C0D	helicase
GTF74_RS05720	ENOG4105DFP	Integrase
GTF74_RS05725	ENOG4105DFP	Integrase
GTF74_RS05750	ENOG4105DY2	Paraquat-inducible protein b
GTF74_RS05755	ENOG4105F1S	paraquat-inducible protein a
GTF74_RS05780	ENOG4108R86	Transcriptional regulator
GTF74_RS05785	ENOG4105C26	Dehydrogenase
GTF74_RS05790	ENOG4105MTM	Protein of unknown function (DUF1496)
GTF74_RS05805	ENOG41067SE	Tetr family transcriptional regulator
GTF74_RS05810	ENOG4107QPN	acyl-Coa dehydrogenase
GTF74_RS05820	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GTF74_RS05840	ENOG4105RKX	Protein of unknown function (DUF2498)
GTF74_RS05845	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GTF74_RS05850	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GTF74_RS05855	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GTF74_RS05875	ENOG4105HP8	regulator of competence-specific genes
GTF74_RS05880	ENOG4105ETE	Transcriptional regulator (LacI family
GTF74_RS05885	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
GTF74_RS05890	ENOG4106WF9	DNA-binding transcriptional regulator TorR
GTF74_RS05895	ENOG4107S90	membrAne
GTF74_RS05900	ENOG4106371	Methyltransferase
GTF74_RS05910	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
GTF74_RS05920	ENOG4105EW9	transcriptional regulator AsnC family
GTF74_RS05930	ENOG4105CCT	upf0313 protein
GTF74_RS05955	ENOG4105DZ2	Transcriptional regulator
GTF74_RS05960	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GTF74_RS05970	ENOG4105K9H	YciI-like protein
GTF74_RS05975	ENOG4105NAU	thioesterase Superfamily protein
GTF74_RS05990	ENOG4105GFG	DUF218 domain
GTF74_RS05995	ENOG4107SRH	Nad-dependent epimerase dehydratase
GTF74_RS06005	ENOG4105TMB	Formate nitrite transporter
GTF74_RS06025	ENOG4107QY8	reductase
GTF74_RS06045	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
GTF74_RS06060	ENOG4108JQ2	peptide transport system atp-binding protein
GTF74_RS06065	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
GTF74_RS06070	ENOG4108EU3	peptide transport system, permease
GTF74_RS06075	ENOG4108I5W	peptide transport system, permease protein
GTF74_RS06080	ENOG4108J59	Extracellular solute-binding protein, family 5
GTF74_RS06085	ENOG4105E51	psp operon transcriptional activator
GTF74_RS06090	ENOG41087YS	Phage shock protein A
GTF74_RS06105	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GTF74_RS06120	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GTF74_RS06125	ENOG4105C28	cystathionine
GTF74_RS06130	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
GTF74_RS06135	ENOG4105C8J	)-transporter
GTF74_RS06140	ENOG4108W1A	pseudouridine synthase
GTF74_RS06145	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
GTF74_RS06150	ENOG4108VGW	abc transporter atp-binding protein
GTF74_RS06155	ENOG4105CXZ	ABC transporter, permease
GTF74_RS06160	ENOG4105VNH	ABC transporter solute-binding protein
GTF74_RS06170	ENOG4105XZD	Fe-S protein
GTF74_RS06180	ENOG4107QWP	ABC-2 type transporter
GTF74_RS06185	ENOG4105CJ1	ABC, transporter
GTF74_RS06195	ENOG4105C44	Serine transporter
GTF74_RS06205	ENOG4105CJW	magnesium transporter
GTF74_RS06215	ENOG4105BZU	Histidine kinase
GTF74_RS06225	ENOG4105KXC	Collagenase
GTF74_RS06255	ENOG4108N3W	hemolysin secretion protein
GTF74_RS06270	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GTF74_RS06290	ENOG4105CFI	type iii restriction protein res subunit
GTF74_RS06295	ENOG4105I08	Pseudouridine synthase
GTF74_RS06300	ENOG4105C2C	drug resistance transporter, Bcr CflA
GTF74_RS06310	ENOG4105CGD	Nad-dependent epimerase dehydratase
GTF74_RS06315	ENOG4105UQX	Mate efflux family protein
GTF74_RS06320	ENOG4108I0Y	(ABC) transporter
GTF74_RS06335	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GTF74_RS06345	ENOG4105E3Q	saccharopine dehydrogenase
GTF74_RS06350	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
GTF74_RS06355	ENOG4105CDV	Ompa motb domain protein
GTF74_RS06360	ENOG4105DFG	type I secretion outer membrane protein
GTF74_RS06380	ENOG4105F04	LysR family Transcriptional regulator
GTF74_RS06390	ENOG4108VKG	metal-dependent hydrolase
GTF74_RS06395	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
GTF74_RS06405	ENOG41090FY	type IV pilus biogenesis stability protein PilW
GTF74_RS06410	ENOG4105CVG	Homoserine O-transsuccinylase
GTF74_RS06430	ENOG4107V40	secretion protein, HlyD family
GTF74_RS06445	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GTF74_RS06450	ENOG4106YYS	transcriptional regulatory protein
GTF74_RS06460	ENOG4107R88	Chemotaxis protein (CheV)
GTF74_RS06505	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GTF74_RS06510	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GTF74_RS06515	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GTF74_RS06520	ENOG4106TD9	Diguanylate cyclase
GTF74_RS06525	ENOG4105BZU	Histidine kinase
GTF74_RS06535	ENOG4105C7K	acetolactate synthase
GTF74_RS06540	ENOG4107FQX	Alpha-acetolactate decarboxylase
GTF74_RS06555	ENOG4105CH6	catalase
GTF74_RS06565	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GTF74_RS06575	ENOG4108TWJ	NADH dehydrogenase subunit 5
GTF74_RS06580	ENOG4105DUM	transcriptional regulator, lysR family
GTF74_RS06585	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
GTF74_RS06615	ENOG4105C9Q	fumarate hydratase class II
GTF74_RS06625	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GTF74_RS06630	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GTF74_RS06635	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GTF74_RS06640	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GTF74_RS06645	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GTF74_RS06655	ENOG4107QZV	Type I secretion membrane fusion protein
GTF74_RS06675	ENOG4105CS2	ec 3.2.1.21
GTF74_RS06680	ENOG4105DDV	Transcriptional regulator (LacI family
GTF74_RS06685	ENOG4105M4H	endoribonuclease L-psp
GTF74_RS06690	ENOG4105XEP	YhcH YjgK YiaL family protein
GTF74_RS06695	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
GTF74_RS06700	ENOG4105E98	transcriptional regulator DeoR family
GTF74_RS06705	ENOG4108IJ9	(ABC) transporter
GTF74_RS06710	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
GTF74_RS06740	ENOG4109015	Biopolymer transport protein exbD tolR
GTF74_RS06745	ENOG41067XB	TonB family
GTF74_RS06765	ENOG4107QI1	Mate efflux family protein
GTF74_RS06785	ENOG4107TT5	NLP P60 protein
GTF74_RS06790	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS06800	ENOG4106IUH	DTW domain containing protein
GTF74_RS06805	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
GTF74_RS06825	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GTF74_RS06830	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GTF74_RS06835	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GTF74_RS06840	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
GTF74_RS06850	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF74_RS06855	ENOG4105BZU	Histidine kinase
GTF74_RS06860	ENOG4105C5H	ABC transporter
GTF74_RS06865	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GTF74_RS06885	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
GTF74_RS06895	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GTF74_RS06900	ENOG4105QAX	Iron-sulfur
GTF74_RS06915	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GTF74_RS06920	ENOG4108VPT	UPF0234 protein
GTF74_RS06925	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GTF74_RS06940	ENOG4105QNR	S1 RNA binding domain protein
GTF74_RS06950	ENOG4105DY2	Paraquat-inducible protein b
GTF74_RS06955	ENOG4105H2K	paraquat-inducible protein a
GTF74_RS06960	ENOG4105BZ1	(ABC) transporter
GTF74_RS06965	ENOG4108ZGC	gaf domain protein
GTF74_RS06970	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
GTF74_RS06975	ENOG4105CN1	protease
GTF74_RS06985	ENOG4105CD8	aminopeptidase N
GTF74_RS06995	ENOG4105C7I	Dehydrogenase
GTF74_RS07000	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GTF74_RS07005	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
GTF74_RS07010	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GTF74_RS07020	ENOG4105C5H	ABC transporter
GTF74_RS07035	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
GTF74_RS07040	ENOG4105DAN	ATP-dependent protease
GTF74_RS07045	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
GTF74_RS07120	ENOG4105TIV	Cryptic phage CTXphi transcriptional repressor RstR
GTF74_RS07140	ENOG4105TIV	Cryptic phage CTXphi transcriptional repressor RstR
GTF74_RS07170	ENOG4105MQ5	zona occludens toxin
GTF74_RS07175	ENOG4107927	Cholera enterotoxin, A subunit
GTF74_RS07185	ENOG4105TIV	Cryptic phage CTXphi transcriptional repressor RstR
GTF74_RS07235	ENOG4105MQ5	zona occludens toxin
GTF74_RS07240	ENOG4107927	Cholera enterotoxin, A subunit
GTF74_RS07250	ENOG4105TIV	Cryptic phage CTXphi transcriptional repressor RstR
GTF74_RS07270	ENOG4105EUK	rtx toxin RtxA
GTF74_RS07275	ENOG4108RC6	RTX toxin
GTF74_RS07300	ENOG4105BZU	Histidine kinase
GTF74_RS07315	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
GTF74_RS07330	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
GTF74_RS07340	ENOG4105C59	p-type ATPase
GTF74_RS07355	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GTF74_RS07360	ENOG4105Q9Y	Universal stress protein
GTF74_RS07385	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GTF74_RS07395	ENOG4105D38	putrescine abc transporter
GTF74_RS07400	ENOG4108HM4	ABC transporter
GTF74_RS07405	ENOG4107RUE	extracellular solute-binding protein family 1
GTF74_RS07420	ENOG4105BZG	amino acid carrier protein
GTF74_RS07425	ENOG410829K	Lysine exporter protein (Lyse ygga)
GTF74_RS07450	ENOG4105CS6	Rhs element vgr protein
GTF74_RS07455	ENOG4108WC9	type VI secretion system effector, hcp1 family
GTF74_RS07460	ENOG4105CTD	carboxy-peptidase
GTF74_RS07465	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS07470	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GTF74_RS07475	ENOG4105CW7	secretion protein, HlyD family
GTF74_RS07480	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GTF74_RS07490	ENOG4105C1J	atp-dependent rna helicase
GTF74_RS07495	ENOG4107SDU	Methyl-accepting chemotaxis
GTF74_RS07500	ENOG4108N3W	hemolysin secretion protein
GTF74_RS07505	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS07510	ENOG4108V3W	Chemotaxis protein, CheW
GTF74_RS07515	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GTF74_RS07525	ENOG4105BZU	Histidine kinase
GTF74_RS07535	ENOG4105CBS	Chea signal transduction histidine kinase
GTF74_RS07550	ENOG4108NVR	Methyl-accepting chemotaxis
GTF74_RS07555	ENOG4105KPY	Small multidrug resistance protein
GTF74_RS07560	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GTF74_RS07565	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GTF74_RS07570	ENOG4105EJC	lysr family transcriptional regulator
GTF74_RS07580	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
GTF74_RS07585	ENOG4105R8A	Heat shock protein
GTF74_RS07595	ENOG4105CQ7	ATP-dependent helicase
GTF74_RS07615	ENOG4105BZU	Histidine kinase
GTF74_RS07625	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GTF74_RS07630	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GTF74_RS07635	ENOG4105BZU	Histidine kinase
GTF74_RS07645	ENOG4105BZU	Histidine kinase
GTF74_RS07665	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GTF74_RS07670	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GTF74_RS07675	ENOG410667J	hydrolase
GTF74_RS07685	ENOG4107QXX	ABC transporter
GTF74_RS07690	ENOG4105EZ7	amino acid ABC transporter
GTF74_RS07695	ENOG4105DRP	amino acid AbC transporter
GTF74_RS07700	ENOG4105CDA	abc transporter atp-binding protein
GTF74_RS07705	ENOG4108MN8	Membrane
GTF74_RS07710	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GTF74_RS07715	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GTF74_RS07720	ENOG4105DR4	Methyltransferase
GTF74_RS07725	ENOG4106TD9	Diguanylate cyclase
GTF74_RS07735	ENOG4105BZU	Histidine kinase
GTF74_RS07740	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GTF74_RS07745	ENOG4108RXX	maleylacetoacetate isomerase
GTF74_RS07755	ENOG4105F1J	Homogentisate 1,2-dioxygenase
GTF74_RS07760	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GTF74_RS07765	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GTF74_RS07780	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GTF74_RS07785	ENOG4105C7F	AcnD-accessory protein PrpF
GTF74_RS07790	ENOG4108I0Z	Aconitate hydratase
GTF74_RS07795	ENOG4105BZN	citrate synthase
GTF74_RS07800	ENOG4105CR4	methylisocitrate lyase
GTF74_RS07835	ENOG4107SDZ	Galactoside transport system permease protein mglC
GTF74_RS07840	ENOG4105C2J	ABC transporter
GTF74_RS07865	ENOG4107EXC	regulatoR
GTF74_RS07870	ENOG4105EB3	Histidine kinase
GTF74_RS07875	ENOG4105RW8	MltA-interacting MipA family protein
GTF74_RS07880	ENOG4108MJ5	VirK protein
GTF74_RS07885	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF74_RS07890	ENOG4105BZU	Histidine kinase
GTF74_RS07895	ENOG4105C8P	)-transporter
GTF74_RS07900	ENOG4108NVR	Methyl-accepting chemotaxis
GTF74_RS07905	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GTF74_RS07920	ENOG4105D9U	N-acetyltransferase
GTF74_RS07925	ENOG4108JU8	Transcriptional regulator
GTF74_RS07935	ENOG4105CM6	amino acid regulated cytosolic protein
GTF74_RS07950	ENOG4105CRQ	synthase (Component I)
GTF74_RS07955	ENOG4105P8F	nudix hydrolase
GTF74_RS07960	ENOG4105C44	Serine transporter
GTF74_RS07965	ENOG4105EJQ	L-serine dehydratase
GTF74_RS07970	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
GTF74_RS07975	ENOG4108NVR	Methyl-accepting chemotaxis
GTF74_RS07980	ENOG4105C5S	asparaginyl-tRNA synthetase
GTF74_RS07990	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GTF74_RS07995	ENOG4105CGF	Aromatic amino acid aminotransferase
GTF74_RS08010	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS08015	ENOG4105DJ9	glucan biosynthesis protein
GTF74_RS08020	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
GTF74_RS08025	ENOG41060NJ	transcriptional regulator
GTF74_RS08035	ENOG4105F8D	glycoside hydrolase family 4
GTF74_RS08040	ENOG4105VCP	PTS System
GTF74_RS08050	ENOG4105VZJ	PTS System
GTF74_RS08060	ENOG4105C94	Transporter
GTF74_RS08065	ENOG41067TZ	transcriptional regulator, MarR family
GTF74_RS08080	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GTF74_RS08090	ENOG4105CH5	extracellular solute-binding protein, family 7
GTF74_RS08105	ENOG4105C5X	domain protein
GTF74_RS08110	ENOG4105EAQ	(twin-arginine translocation) pathway signal
GTF74_RS08115	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
GTF74_RS08140	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GTF74_RS08150	ENOG4105S8Q	sugar efflux transporter
GTF74_RS08160	ENOG4105C72	UPF0176 protein
GTF74_RS08165	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GTF74_RS08170	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GTF74_RS08175	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GTF74_RS08180	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GTF74_RS08185	ENOG4107QK7	reductase
GTF74_RS08210	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS08230	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
GTF74_RS08245	ENOG4108YZT	Adenosylcobinamide kinase
GTF74_RS08250	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
GTF74_RS08255	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
GTF74_RS08260	ENOG4105E0X	reductase
GTF74_RS08265	ENOG4108ETY	sodium dicarboxylate symporter
GTF74_RS08270	ENOG4105CJB	Exodeoxyribonuclease I
GTF74_RS08275	ENOG4105VAW	lrga family
GTF74_RS08280	ENOG41067MG	lrgb family
GTF74_RS08310	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GTF74_RS08315	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GTF74_RS08320	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GTF74_RS08360	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GTF74_RS08365	ENOG4105WH1	Two component transcriptional regulator luxr family
GTF74_RS08370	ENOG4105CQ2	DNA polymerase
GTF74_RS08375	ENOG4105BZU	Histidine kinase
GTF74_RS08385	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GTF74_RS08390	ENOG4108W5H	UPF0263 protein
GTF74_RS08400	ENOG4105CZE	histidine utilization repressor
GTF74_RS08405	ENOG4105CI2	imidazolone-5-propionate hydrolase
GTF74_RS08410	ENOG41088SP	formiminoglutamate hydrolase
GTF74_RS08415	ENOG4105CGP	Urocanate hydratase
GTF74_RS08420	ENOG4105C84	Histidine ammonia-lyase
GTF74_RS08430	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
GTF74_RS08440	ENOG4105CQB	FAD linked oxidase domain protein
GTF74_RS08455	ENOG4108ZG0	Ompa motb domain protein
GTF74_RS08475	ENOG4105C8V	SAICAR synthetase
GTF74_RS08485	ENOG4107R1I	NAD-dependent malic enzyme
GTF74_RS08495	ENOG4107GZ4	SanA protein
GTF74_RS08500	ENOG4105BZU	Histidine kinase
GTF74_RS08505	ENOG4105C9B	Cysteine desulfurase
GTF74_RS08515	ENOG4105C3M	thioredoxin reductase
GTF74_RS08520	ENOG4108JJ9	ABC, transporter
GTF74_RS08525	ENOG4108JJ8	(ABC) transporter
GTF74_RS08530	ENOG4105FE9	pseudouridine synthase
GTF74_RS08535	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GTF74_RS08540	ENOG4105DB7	PHP domain protein
GTF74_RS08550	ENOG4105CRQ	synthase (Component I)
GTF74_RS08555	ENOG4105DDQ	anthranilate synthase
GTF74_RS08560	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GTF74_RS08565	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GTF74_RS08570	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GTF74_RS08575	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GTF74_RS08580	ENOG4105CK2	sodium dicarboxylate symporter
GTF74_RS08585	ENOG4107104	thymidine kinase
GTF74_RS08590	ENOG4105C9M	aspartyl-trna synthetase
GTF74_RS08595	ENOG41081XQ	Conserved Protein
GTF74_RS08600	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
GTF74_RS08605	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
GTF74_RS08610	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GTF74_RS08625	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GTF74_RS08635	ENOG4105CUX	Signal transduction histidine kinase
GTF74_RS08660	ENOG4105DWU	Membrane
GTF74_RS08670	ENOG4105DY8	decarboxylase
GTF74_RS08675	ENOG4106KNT	transcriptional regulator
GTF74_RS08680	ENOG4105C0A	alcohol dehydrogenase
GTF74_RS08685	ENOG41090BQ	Glutaredoxin
GTF74_RS08690	ENOG4105D0C	transport protein
GTF74_RS08695	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GTF74_RS08700	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GTF74_RS08705	ENOG4105VEQ	Cold shock protein
GTF74_RS08715	ENOG4108R99	pseudouridine synthase
GTF74_RS08720	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GTF74_RS08725	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GTF74_RS08730	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GTF74_RS08735	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GTF74_RS08740	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GTF74_RS08745	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GTF74_RS08750	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GTF74_RS08755	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GTF74_RS08760	ENOG4107S6Z	Na H antiporter
GTF74_RS08770	ENOG4107RE1	Inosine-guanosine kinase
GTF74_RS08775	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GTF74_RS08780	ENOG41075W9	High frequency lysogenization protein HflD homolog
GTF74_RS08785	ENOG4107QTF	adenylosuccinate lyase
GTF74_RS08795	ENOG4105RHG	
GTF74_RS08805	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GTF74_RS08820	ENOG4107FW0	short-chain dehydrogenase reductase
GTF74_RS08830	ENOG4105D0M	Protease HtpX homolog
GTF74_RS08840	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GTF74_RS08845	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GTF74_RS08850	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GTF74_RS08855	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GTF74_RS08860	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GTF74_RS08865	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GTF74_RS08870	ENOG4105D1H	recombination factor protein RarA
GTF74_RS08880	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GTF74_RS08885	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
GTF74_RS08890	ENOG4105BZU	Histidine kinase
GTF74_RS08895	ENOG4108JJB	ABC transporter
GTF74_RS08900	ENOG4105C7J	ABC transporter, permease
GTF74_RS08910	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GTF74_RS08915	ENOG4105PQ6	UPF0208 membrane protein
GTF74_RS08920	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GTF74_RS08925	ENOG4108DNC	Involved in acetate metabolism (By similarity)
GTF74_RS08930	ENOG4105CHF	Glutathione S-transferase
GTF74_RS08935	ENOG4108JQ7	(ABC) transporter
GTF74_RS08940	ENOG4105C3U	ABC transporter
GTF74_RS08945	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GTF74_RS08950	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GTF74_RS08955	ENOG4107QSI	ABC, transporter
GTF74_RS08970	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF74_RS08975	ENOG4105BZU	Histidine kinase
GTF74_RS08980	ENOG4105BZU	Histidine kinase
GTF74_RS08985	ENOG4105BZU	Histidine kinase
GTF74_RS08995	ENOG4107YTP	response regulator receiver protein
GTF74_RS09010	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GTF74_RS09025	ENOG4108V1U	phospholipid-binding protein
GTF74_RS09050	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GTF74_RS09055	ENOG41082YX	Transcriptional regulator, arsr family
GTF74_RS09065	ENOG4105BZU	Histidine kinase
GTF74_RS09085	ENOG4105C29	acyl-CoA thioesterase
GTF74_RS09090	ENOG4108XM1	transcriptional regulator AsnC family
GTF74_RS09100	ENOG4105ERU	peptidase
GTF74_RS09105	ENOG4105UBK	short-chain dehydrogenase reductase
GTF74_RS09110	ENOG4108ZZ3	UPF0260 protein
GTF74_RS09115	ENOG4105KRS	Proteinase inhibitor
GTF74_RS09120	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GTF74_RS09125	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GTF74_RS09130	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GTF74_RS09135	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GTF74_RS09140	ENOG4105WD1	Membrane
GTF74_RS09145	ENOG4105I93	response regulator
GTF74_RS09150	ENOG4105EJC	lysr family transcriptional regulator
GTF74_RS09155	ENOG41069NU	Nitroreductase
GTF74_RS09160	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GTF74_RS09165	ENOG4105CHU	acetyl-coa acetyltransferase
GTF74_RS09180	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GTF74_RS09185	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GTF74_RS09195	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
GTF74_RS09200	ENOG4108GAE	asmA family
GTF74_RS09205	ENOG4105DBI	uridine monophosphokinase
GTF74_RS09210	ENOG4105D1F	ATP-binding protein
GTF74_RS09215	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GTF74_RS09225	ENOG4108I5U	Uridine phosphorylase
GTF74_RS09240	ENOG4105BZU	Histidine kinase
GTF74_RS09245	ENOG4108ZAF	Molybdopterin
GTF74_RS09250	ENOG4105M00	molybdopterin converting factor, subunit 1
GTF74_RS09255	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GTF74_RS09260	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GTF74_RS09265	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GTF74_RS09270	ENOG4105CHW	UPF0052 protein
GTF74_RS09280	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF74_RS09285	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GTF74_RS09300	ENOG4108R3D	Electron transport complex
GTF74_RS09325	ENOG4105CSM	endonuclease III
GTF74_RS09330	ENOG4108UYE	Lactoylglutathione lyase
GTF74_RS09335	ENOG4106WH9	Protein of unknown function (DUF2753)
GTF74_RS09340	ENOG4105EIY	sodium-type flagellar protein motY
GTF74_RS09345	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GTF74_RS09350	ENOG4105D3Y	Na H antiporter
GTF74_RS09355	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GTF74_RS09360	ENOG4105E96	Colicin v production protein
GTF74_RS09365	ENOG4108S3P	Sporulation domain protein
GTF74_RS09370	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GTF74_RS09375	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GTF74_RS09380	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GTF74_RS09395	ENOG4105CI1	PTS System
GTF74_RS09400	ENOG4105CE4	GlcNAc 6-P deacetylase
GTF74_RS09405	ENOG4105E2R	ROK family
GTF74_RS09410	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GTF74_RS09415	ENOG4105CAQ	asparagine synthetase
GTF74_RS09420	ENOG4105MDZ	Transcriptional activator rfaH
GTF74_RS09425	ENOG4105DUX	Transporter
GTF74_RS09430	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GTF74_RS09435	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GTF74_RS09440	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GTF74_RS09445	ENOG4108TU9	TRANSCRIPTIONal
GTF74_RS09460	ENOG4108RE9	Phosphodiesterase
GTF74_RS09465	ENOG4105ECP	epimerase
GTF74_RS09470	ENOG4105E1F	short-chain dehydrogenase reductase
GTF74_RS09475	ENOG4107QR8	Thioredoxin
GTF74_RS09480	ENOG4107QX8	SPFH domain, Band 7 family protein
GTF74_RS09485	ENOG4105G5H	Membrane
GTF74_RS09490	ENOG4108Z6Z	Transcriptional regulator
GTF74_RS09500	ENOG41081QG	Porin Gram-negative type
GTF74_RS09505	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GTF74_RS09510	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GTF74_RS09515	ENOG4105EXN	Sulfate transport protein CysZ
GTF74_RS09520	ENOG4105C6T	cysteine synthase
GTF74_RS09525	ENOG4105KZ7	phosphocarrier protein hpr
GTF74_RS09530	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GTF74_RS09535	ENOG4105C5Y	PTS System
GTF74_RS09540	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GTF74_RS09545	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GTF74_RS09550	ENOG4105C9A	Phoh family
GTF74_RS09560	ENOG4108JU5	Magnesium and cobalt efflux protein
GTF74_RS09565	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GTF74_RS09570	ENOG4107PAI	alpha helical protein
GTF74_RS09575	ENOG4105C8T	Leucyl-tRNA synthetase
GTF74_RS09580	ENOG4108U2H	Rare lipoprotein B
GTF74_RS09585	ENOG4105DJF	DNA polymerase III, delta' subunit
GTF74_RS09590	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GTF74_RS09595	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GTF74_RS09600	ENOG4105CJN	penicillin-binding protein
GTF74_RS09605	ENOG4105CNI	cell division protein FtsW
GTF74_RS09610	ENOG4105K6T	rare lipoprotein A
GTF74_RS09615	ENOG4105DZ1	carboxypeptidase
GTF74_RS09620	ENOG4108Z43	UPF0250 protein
GTF74_RS09625	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GTF74_RS09630	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GTF74_RS09640	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GTF74_RS09660	ENOG4105D75	Capsular exopolysaccharide family
GTF74_RS09665	ENOG4105DAY	polysaccharide export protein
GTF74_RS09675	ENOG4105D3Q	Sugar transferase
GTF74_RS09690	ENOG4108MA4	Peptidase M66
GTF74_RS09705	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
GTF74_RS09715	ENOG4105Q84	sucrose synthase
GTF74_RS09725	ENOG4105D7W	serine acetyltransferase
GTF74_RS09745	ENOG4108UW5	maltose o-acetyltransferase
GTF74_RS09755	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GTF74_RS09760	ENOG4107ZF2	Phosphatase
GTF74_RS09765	ENOG4105BZS	acriflavin resistance protein
GTF74_RS09795	ENOG4105CG3	alpha amylase, catalytic region
GTF74_RS09800	ENOG4105C5Y	PTS System
GTF74_RS09805	ENOG4105D4X	repressor
GTF74_RS09810	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GTF74_RS09815	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GTF74_RS09820	ENOG4108UMI	ABC transporter, permease
GTF74_RS09825	ENOG4105D01	(LipO)protein
GTF74_RS09830	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
GTF74_RS09835	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
GTF74_RS09840	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GTF74_RS09850	ENOG4105BZU	Histidine kinase
GTF74_RS09855	ENOG4105EWT	decarboxylase family
GTF74_RS09860	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
GTF74_RS09865	ENOG4105M08	Membrane
GTF74_RS09870	ENOG4105ETT	transcriptional Regulator, LysR family
GTF74_RS09875	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GTF74_RS09880	ENOG4106VK6	Flagellar motor protein
GTF74_RS09885	ENOG4105E14	MotA TolQ exbB proton channel
GTF74_RS09895	ENOG4105CTB	Polyprenyl synthetase
GTF74_RS09900	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GTF74_RS09905	ENOG4105DR9	pseudouridine synthase
GTF74_RS09910	ENOG4105WP7	tRNA pseudouridine synthase C
GTF74_RS09925	ENOG4108428	Inherit from COG: -acetyltransferase
GTF74_RS09935	ENOG4108UPT	UPF0178 protein
GTF74_RS09940	ENOG4105CFC	Transporter
GTF74_RS09950	ENOG4105NRA	50s ribosomal protein l31 type b
GTF74_RS09955	ENOG4108R96	Methyltransferase, YaeB family
GTF74_RS09960	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GTF74_RS09980	ENOG4108RS6	transposase
GTF74_RS09985	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GTF74_RS09995	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GTF74_RS10000	ENOG4108Z6B	deaminase
GTF74_RS10005	ENOG4105CFC	Transporter
GTF74_RS10035	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GTF74_RS10040	ENOG4105CFG	Acts as a chaperone (By similarity)
GTF74_RS10050	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GTF74_RS10055	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GTF74_RS10060	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GTF74_RS10065	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GTF74_RS10070	ENOG4105VDB	UPF0125 protein
GTF74_RS10075	ENOG4108Z1B	Cyclase dehydrase
GTF74_RS10080	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GTF74_RS10090	ENOG4105DFP	Integrase
GTF74_RS10100	ENOG4105DFP	Integrase
GTF74_RS10105	ENOG4105F88	accessory colonization factor AcfD
GTF74_RS10115	ENOG4105DR5	peptidase
GTF74_RS10130	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS10135	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GTF74_RS10150	ENOG4108VEY	type ii secretion system
GTF74_RS10155	ENOG4107QHF	type ii secretion system protein e
GTF74_RS10175	ENOG4105GRU	toxin co-regulated pilus biosynthesis outer membrane protein C
GTF74_RS10190	ENOG4105XB6	Toxin coregulated pilin
GTF74_RS10205	ENOG4107RK6	Methyl-accepting chemotaxis
GTF74_RS10210	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
GTF74_RS10230	ENOG4105C26	Dehydrogenase
GTF74_RS10285	ENOG4105DZ0	fad dependent oxidoreductase
GTF74_RS10290	ENOG4108Z4U	Ferredoxin
GTF74_RS10315	ENOG4105CHY	citrate lyase, alpha
GTF74_RS10320	ENOG4105CI0	Citrate lyase
GTF74_RS10330	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
GTF74_RS10335	ENOG4105D2K	citrate carrier protein
GTF74_RS10345	ENOG4107QSA	Oxaloacetate decarboxylase
GTF74_RS10350	ENOG4105D9Q	decarboxylase (Beta subunit)
GTF74_RS10355	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GTF74_RS10360	ENOG4106YYS	transcriptional regulatory protein
GTF74_RS10385	ENOG4105BZG	amino acid carrier protein
GTF74_RS10390	ENOG4105EUZ	Beta-lactamase domain protein
GTF74_RS10395	ENOG41064T2	transcriptional regulator, lysR family
GTF74_RS10405	ENOG4105E0A	ABC, transporter
GTF74_RS10410	ENOG4105TVJ	transport system, permease
GTF74_RS10415	ENOG4105DQ5	transport system permease protein
GTF74_RS10420	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
GTF74_RS10430	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
GTF74_RS10435	ENOG4105E4F	Isochorismate synthase
GTF74_RS10440	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
GTF74_RS10445	ENOG4105WQI	isochorismatase
GTF74_RS10450	ENOG4106HK8	GPR1 FUN34 yaaH family protein
GTF74_RS10460	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GTF74_RS10465	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GTF74_RS10470	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GTF74_RS10485	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GTF74_RS10490	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GTF74_RS10495	ENOG4105N21	Membrane
GTF74_RS10500	ENOG4105CUT	histidyl-tRNA synthetase
GTF74_RS10505	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GTF74_RS10515	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GTF74_RS10520	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GTF74_RS10525	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GTF74_RS10530	ENOG4105WVQ	Fe-S assembly protein IscX
GTF74_RS10535	ENOG4108ZIT	Ferredoxin, 2FE-2S
GTF74_RS10540	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GTF74_RS10545	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
GTF74_RS10550	ENOG4108Z4V	iron-sulfur cluster assembly
GTF74_RS10555	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GTF74_RS10560	ENOG4105C3J	Cysteine desulfurase
GTF74_RS10565	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GTF74_RS10570	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
GTF74_RS10575	ENOG4105ECY	inositol monophosphatase
GTF74_RS10580	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GTF74_RS10585	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GTF74_RS10590	ENOG4105VIE	preprotein translocase, subunit YajC
GTF74_RS10605	ENOG4105W87	Cbs domain
GTF74_RS10610	ENOG4108I9X	Isocitrate lyase
GTF74_RS10615	ENOG4107QP3	malate synthase g
GTF74_RS10620	ENOG4105C5Q	Transcriptional regulator
GTF74_RS10625	ENOG4105D3R	alkyl hydroperoxide reductase
GTF74_RS10630	ENOG4106N3A	copper homeostasis protein cutc
GTF74_RS10635	ENOG4105CSR	polyphosphate kinase 2
GTF74_RS10645	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GTF74_RS10650	ENOG4105E2Z	phosphate ABC transporter (Permease
GTF74_RS10655	ENOG4105C8U	phosphate abc transporter
GTF74_RS10660	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GTF74_RS10665	ENOG4105C9X	ppx gppa phosphatase
GTF74_RS10670	ENOG4105DJH	phosphate
GTF74_RS10675	ENOG4105BZU	Histidine kinase
GTF74_RS10680	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GTF74_RS10690	ENOG4105CFP	Peptidase U32
GTF74_RS10695	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GTF74_RS10735	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GTF74_RS10740	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GTF74_RS10745	ENOG4105C34	Pseudouridine synthase
GTF74_RS10750	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTF74_RS10755	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
GTF74_RS10765	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
GTF74_RS10770	ENOG4108K0B	C-di-gmp phosphodiesterase
GTF74_RS10780	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
GTF74_RS10785	ENOG4107SC1	transglycosylase
GTF74_RS10790	ENOG4105C5H	ABC transporter
GTF74_RS10805	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GTF74_RS10810	ENOG4108HRK	Histidine kinase
GTF74_RS10815	ENOG4108NEV	two component transcriptional regulator, LytTR family
GTF74_RS10825	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GTF74_RS10830	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GTF74_RS10850	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GTF74_RS10855	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GTF74_RS10870	ENOG4105DTN	riboflavin biosynthesis protein ribF
GTF74_RS10875	ENOG4105CJR	Integral membrane protein (MviN
GTF74_RS10880	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GTF74_RS10885	ENOG41080HT	Transcriptional regulator, arsr family
GTF74_RS10890	ENOG41063Z6	transcriptional regulator, lysR family
GTF74_RS10905	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GTF74_RS10910	ENOG4105HF0	Membrane
GTF74_RS10915	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
GTF74_RS10920	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GTF74_RS10930	ENOG4105CPC	Aldo Keto reductase
GTF74_RS10940	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF74_RS10945	ENOG4105CRK	lysyL-tRNA synthetase
GTF74_RS10955	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GTF74_RS10965	ENOG4105C1J	atp-dependent rna helicase
GTF74_RS10975	ENOG4105BZU	Histidine kinase
GTF74_RS10990	ENOG4108YYD	acetyltransferase
GTF74_RS11000	ENOG4105BZU	Histidine kinase
GTF74_RS11035	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GTF74_RS11045	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GTF74_RS11050	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GTF74_RS11055	ENOG4105CHV	Transcription elongation factor NusA
GTF74_RS11060	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GTF74_RS11075	ENOG4105NTZ	Preprotein translocase subunit SecG
GTF74_RS11085	ENOG4105EEI	dihydropteroate synthase
GTF74_RS11090	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GTF74_RS11095	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GTF74_RS11100	ENOG4105HBR	Rna-binding protein
GTF74_RS11105	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GTF74_RS11110	ENOG4105FCK	Membrane
GTF74_RS11115	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GTF74_RS11120	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GTF74_RS11125	ENOG4105DR5	peptidase
GTF74_RS11140	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GTF74_RS11145	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GTF74_RS11150	ENOG4105IPI	Membrane
GTF74_RS11155	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GTF74_RS11165	ENOG4107QRA	Extracellular solute-binding protein, family 5
GTF74_RS11175	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GTF74_RS11180	ENOG4105C3U	ABC transporter
GTF74_RS11185	ENOG4108JQ7	(ABC) transporter
GTF74_RS11195	ENOG4105RD7	BadF BadG BcrA BcrD
GTF74_RS11200	ENOG4105E2D	ec 3.2.1.52
GTF74_RS11205	ENOG4105E2V	Glycosyltransferase 36
GTF74_RS11215	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GTF74_RS11240	ENOG4105XTV	UPF0231 protein
GTF74_RS11245	ENOG4107QIJ	Aconitate hydratase 2
GTF74_RS11250	ENOG4105D78	K07001 NTE family protein
GTF74_RS11255	ENOG4105BZ4	penicillin-binding protein
GTF74_RS11260	ENOG4105CQ7	ATP-dependent helicase
GTF74_RS11270	ENOG4105PW4	Sugar fermentation stimulation protein homolog
GTF74_RS11275	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GTF74_RS11280	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GTF74_RS11285	ENOG4105DJ0	Poly(A) Polymerase
GTF74_RS11290	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GTF74_RS11295	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GTF74_RS11300	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GTF74_RS11305	ENOG4105E3A	(ABC) transporter
GTF74_RS11310	ENOG4105DA5	(ABC) transporter
GTF74_RS11315	ENOG4105CHH	sulfate transporter
GTF74_RS11320	ENOG41077A9	carbonic anhydrase
GTF74_RS11325	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GTF74_RS11330	ENOG410630P	Transcriptional regulator
GTF74_RS11335	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GTF74_RS11340	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
GTF74_RS11345	ENOG41082RQ	UPF0102 protein
GTF74_RS11350	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GTF74_RS11355	ENOG4105W4M	Transport-associated protein
GTF74_RS11360	ENOG4105KB2	stringent starvation protein b
GTF74_RS11365	ENOG4107MKT	Stringent starvation protein a
GTF74_RS11370	ENOG4105EIX	cytochrome c1
GTF74_RS11375	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GTF74_RS11380	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GTF74_RS11385	ENOG4108UJD	30S ribosomal protein S9
GTF74_RS11390	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GTF74_RS11395	ENOG4105D6Z	AFG1 family ATPase
GTF74_RS11405	ENOG4105C0H	protease
GTF74_RS11410	ENOG4105C0H	protease
GTF74_RS11415	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GTF74_RS11420	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GTF74_RS11425	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GTF74_RS11430	ENOG4105K5M	30s ribosomal protein S16
GTF74_RS11435	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GTF74_RS11440	ENOG4106KVJ	cytochrome C assembly protein
GTF74_RS11445	ENOG4108JU6	CBS domain protein
GTF74_RS11450	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GTF74_RS11455	ENOG4105D9M	gamma-glutamylcysteine synthetase
GTF74_RS11465	ENOG4105W39	Membrane
GTF74_RS11475	ENOG4105D9Q	decarboxylase (Beta subunit)
GTF74_RS11480	ENOG4107QSA	Oxaloacetate decarboxylase
GTF74_RS11530	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GTF74_RS11535	ENOG4105CFH	Aspartokinase
GTF74_RS11540	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GTF74_RS11550	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GTF74_RS11560	ENOG4108IJ6	ABC transporter
GTF74_RS11565	ENOG4105ECW	sulfate abc transporter
GTF74_RS11570	ENOG4108I5D	sulfate abc transporter
GTF74_RS11575	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
GTF74_RS11580	ENOG4105C6T	cysteine synthase
GTF74_RS11585	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GTF74_RS11590	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GTF74_RS11595	ENOG4108K5P	(LipO)protein
GTF74_RS11600	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GTF74_RS11605	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GTF74_RS11610	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
GTF74_RS11615	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GTF74_RS11620	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GTF74_RS11630	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GTF74_RS11635	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GTF74_RS11640	ENOG4107ZVW	dihydroneopterin aldolase
GTF74_RS11645	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GTF74_RS11655	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GTF74_RS11660	ENOG4105VCC	30S ribosomal protein S21
GTF74_RS11665	ENOG4105KTH	gatB Yqey
GTF74_RS11670	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GTF74_RS11675	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GTF74_RS11685	ENOG4105DFP	Integrase
GTF74_RS11690	ENOG4105D58	Diguanylate phosphodiesterase
GTF74_RS11695	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS11705	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GTF74_RS11715	ENOG4108YGG	dna repair protein
GTF74_RS11745	ENOG4105DR5	peptidase
GTF74_RS11770	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GTF74_RS11820	ENOG4105CH5	extracellular solute-binding protein, family 7
GTF74_RS11825	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GTF74_RS11830	ENOG410804X	Transcriptional regulator
GTF74_RS11835	ENOG4105CA9	Pyruvate kinase
GTF74_RS11840	ENOG4105MPN	Membrane
GTF74_RS11850	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
GTF74_RS11855	ENOG4105D64	Mechanosensitive ion channel
GTF74_RS11860	ENOG4105D2N	Aldolase
GTF74_RS11865	ENOG4105BZA	Phosphoglycerate kinase
GTF74_RS11870	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GTF74_RS11875	ENOG4105D05	Receptor
GTF74_RS11880	ENOG4108R4R	Iron-regulated virulence regulatory protein
GTF74_RS11885	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GTF74_RS11890	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GTF74_RS11900	ENOG4105RWS	endonuclease I
GTF74_RS11905	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GTF74_RS11910	ENOG4105D7Z	glutathione synthase
GTF74_RS11915	ENOG4108UJU	UPF0301 protein
GTF74_RS11920	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GTF74_RS11925	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GTF74_RS11935	ENOG4105CZX	twitching motility protein
GTF74_RS11940	ENOG4105CZX	twitching motility protein
GTF74_RS11945	ENOG4105DFA	alanine racemase domain protein
GTF74_RS11950	ENOG4105II7	pyrroline-5-carboxylate reductase
GTF74_RS11955	ENOG4108VIA	integral membrane protein
GTF74_RS11960	ENOG4105VZ9	UPF0235 protein
GTF74_RS11970	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GTF74_RS11975	ENOG4105CSA	Coproporphyrinogen iii oxidase
GTF74_RS11980	ENOG4105CSV	Glutaminase
GTF74_RS11990	ENOG4105CEN	a g-specific adenine glycosylase
GTF74_RS11995	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GTF74_RS12000	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
GTF74_RS12055	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GTF74_RS12060	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GTF74_RS12065	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GTF74_RS12070	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GTF74_RS12075	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GTF74_RS12080	ENOG4105NWN	ApaG protein
GTF74_RS12085	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GTF74_RS12095	ENOG4107XM3	UPF0442 protein
GTF74_RS12100	ENOG4105DWK	Membrane
GTF74_RS12105	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GTF74_RS12110	ENOG4105K46	50S ribosomal protein l27
GTF74_RS12115	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GTF74_RS12120	ENOG4105EAH	synthase
GTF74_RS12125	ENOG4105D5Q	Arginine ornithine antiporter
GTF74_RS12130	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GTF74_RS12135	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GTF74_RS12140	ENOG4105H1G	trap transporter solute receptor taxi family
GTF74_RS12150	ENOG41081QV	Universal stress protein
GTF74_RS12170	ENOG4105CEU	Arginine dihydrolase
GTF74_RS12175	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GTF74_RS12185	ENOG4105QD6	exported protein
GTF74_RS12190	ENOG4105C03	ribonuclease
GTF74_RS12195	ENOG4108Z03	MAF-like protein
GTF74_RS12200	ENOG4105VQ7	Rod shape-determining protein MreD
GTF74_RS12205	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GTF74_RS12245	ENOG4105X0D	Fimbrial protein
GTF74_RS12255	ENOG4105D7Q	type ii secretion system
GTF74_RS12260	ENOG4107QHF	type ii secretion system protein e
GTF74_RS12275	ENOG4105E4G	Type IV pilus
GTF74_RS12295	ENOG41062P1	Diguanylate cyclase phosphodiesterase
GTF74_RS12300	ENOG4108UUM	single-stranded DNA-binding protein
GTF74_RS12305	ENOG41086KC	Transcriptional regulator
GTF74_RS12310	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GTF74_RS12315	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GTF74_RS12325	ENOG4105C5R	Aminotransferase
GTF74_RS12330	ENOG4105CFH	Aspartokinase
GTF74_RS12335	ENOG4105C3R	Methionine synthase
GTF74_RS12340	ENOG4105EEQ	Na H antiporter
GTF74_RS12405	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GTF74_RS12415	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GTF74_RS12435	ENOG4105P4Z	Phage shock protein G
GTF74_RS12440	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GTF74_RS12445	ENOG4105MYN	Zinc uptake regulation protein
GTF74_RS12465	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GTF74_RS12470	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GTF74_RS12475	ENOG4105CDU	Replicative dna helicase
GTF74_RS12485	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GTF74_RS12490	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GTF74_RS12495	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
GTF74_RS12500	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GTF74_RS12505	ENOG4108UQY	Iron-storage protein
GTF74_RS12510	ENOG4105W53	bacterioferritin-associated ferredoxin
GTF74_RS12515	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GTF74_RS12520	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GTF74_RS12525	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GTF74_RS12530	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GTF74_RS12540	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GTF74_RS12545	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
GTF74_RS12550	ENOG4105WWK	YheO domain protein
GTF74_RS12565	ENOG41069P5	Protein slyX homolog
GTF74_RS12575	ENOG4105EPW	hflc protein
GTF74_RS12580	ENOG4107QJR	hflk protein
GTF74_RS12585	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GTF74_RS12590	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GTF74_RS12595	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GTF74_RS12600	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GTF74_RS12605	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GTF74_RS12610	ENOG4105K8N	protein family UPF0079, ATPase
GTF74_RS12615	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GTF74_RS12660	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GTF74_RS12665	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GTF74_RS12670	ENOG4105DJ4	phosphatidylserine decarboxylase
GTF74_RS12675	ENOG4105C8P	)-transporter
GTF74_RS12685	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GTF74_RS12700	ENOG41062JF	Transcriptional regulator
GTF74_RS12705	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GTF74_RS12710	ENOG4105E09	nadh pyrophosphatase
GTF74_RS12715	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
GTF74_RS12720	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GTF74_RS12725	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GTF74_RS12730	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GTF74_RS12735	ENOG4108VZM	50s ribosomal protein L10
GTF74_RS12745	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GTF74_RS12750	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GTF74_RS12755	ENOG4105PM1	preprotein translocase subunit SecE
GTF74_RS12760	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GTF74_RS12785	ENOG4105CS9	pantothenic acid kinase
GTF74_RS12790	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GTF74_RS12795	ENOG4105D4A	Cell wall formation (By similarity)
GTF74_RS12805	ENOG4105JIM	Phosphatidylserine synthase
GTF74_RS12840	ENOG4107QK7	reductase
GTF74_RS12850	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GTF74_RS12860	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GTF74_RS12870	ENOG4105C1J	atp-dependent rna helicase
GTF74_RS12875	ENOG4105C9X	ppx gppa phosphatase
GTF74_RS12880	ENOG4105BZU	Histidine kinase
GTF74_RS12885	ENOG4105D8G	Major Facilitator superfamily
GTF74_RS12900	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GTF74_RS12905	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GTF74_RS12910	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GTF74_RS12915	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GTF74_RS12920	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GTF74_RS12925	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GTF74_RS12930	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
GTF74_RS12935	ENOG4105DIQ	Transcriptional regulator
GTF74_RS12940	ENOG4105C01	Dihydroxy-acid dehydratase
GTF74_RS12945	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GTF74_RS12950	ENOG4105C6Z	Gluconate
GTF74_RS12955	ENOG4108UHU	Aldolase
GTF74_RS12960	ENOG4105E0K	tonB-dependent siderophore receptor
GTF74_RS12975	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS12980	ENOG4105CXN	decarboxylase
GTF74_RS12985	ENOG4105D5Q	Arginine ornithine antiporter
GTF74_RS12990	ENOG4108M3R	transcriptional activator CadC
GTF74_RS12995	ENOG4105W1Y	Transcriptional regulator
GTF74_RS13010	ENOG4105C12	Phosphoribosylglycinamide synthetase
GTF74_RS13020	ENOG4105K70	DNA-binding protein
GTF74_RS13030	ENOG4105DKQ	ROK family
GTF74_RS13035	ENOG4105EIP	mannose-6-phosphate isomerase
GTF74_RS13040	ENOG4105R2J	Conserved Protein
GTF74_RS13045	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
GTF74_RS13050	ENOG4108RG0	uracil-dna glycosylase
GTF74_RS13055	ENOG4105CUY	Mechanosensitive ion channel
GTF74_RS13060	ENOG4105CY0	Metallo-Beta-Lactamase
GTF74_RS13065	ENOG4105D3Q	Sugar transferase
GTF74_RS13100	ENOG4108UT6	Transferase hexapeptide repeat containing protein
GTF74_RS13110	ENOG4105C0A	alcohol dehydrogenase
GTF74_RS13115	ENOG4105CEY	Amp-dependent synthetase and ligase
GTF74_RS13125	ENOG4105EY8	ABC transporter
GTF74_RS13140	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GTF74_RS13145	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
GTF74_RS13150	ENOG4107QKV	phosphomannomutase
GTF74_RS13155	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
GTF74_RS13160	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GTF74_RS13165	ENOG4107T94	Endo-14-beta-xylanase
GTF74_RS13180	ENOG4105XA0	heptosyltransferase ii
GTF74_RS13190	ENOG4108ST3	glycosyltransferase
GTF74_RS13195	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GTF74_RS13225	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
GTF74_RS13230	ENOG4105DKP	glycosyl transferase, family 9
GTF74_RS13235	ENOG4106WTF	Glycosyl transferase, family 2
GTF74_RS13240	ENOG4105M5K	heptosyltransferase
GTF74_RS13245	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GTF74_RS13250	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GTF74_RS13260	ENOG4105W0E	50S ribosomal protein L33
GTF74_RS13265	ENOG4105KDC	50s ribosomal protein l28
GTF74_RS13270	ENOG4105W5Q	DNA repair protein (RadC
GTF74_RS13275	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS13280	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GTF74_RS13290	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GTF74_RS13295	ENOG4105D1S	lipid A biosynthesis
GTF74_RS13300	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
GTF74_RS13305	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GTF74_RS13310	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GTF74_RS13315	ENOG4105DSJ	YicC domain protein
GTF74_RS13320	ENOG4108TEB	UPF0114 protein
GTF74_RS13325	ENOG4105C5Y	PTS System
GTF74_RS13330	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GTF74_RS13335	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
GTF74_RS13340	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
GTF74_RS13345	ENOG4105J76	Periplasmic binding protein
GTF74_RS13350	ENOG4105E0A	ABC, transporter
GTF74_RS13355	ENOG4105E0K	tonB-dependent siderophore receptor
GTF74_RS13360	ENOG4105BZ1	(ABC) transporter
GTF74_RS13375	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GTF74_RS13380	ENOG4105FR1	rard protein
GTF74_RS13390	ENOG4108DMH	HTH_ARAC
GTF74_RS13395	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
GTF74_RS13400	ENOG4105C4R	Atp-dependent dna helicase
GTF74_RS13405	ENOG4105DGW	oligopeptidase A
GTF74_RS13410	ENOG4105D6S	protein involved in catabolism of external DNA
GTF74_RS13415	ENOG4105DC8	reductase
GTF74_RS13450	ENOG4108ZXE	
GTF74_RS13480	ENOG4108UK2	deaminase
GTF74_RS13490	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GTF74_RS13495	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GTF74_RS13500	ENOG4105DEF	Extracellular solute-binding protein, family 5
GTF74_RS13540	ENOG4105MPD	Cytochrome
GTF74_RS13545	ENOG4105C4R	Atp-dependent dna helicase
GTF74_RS13550	ENOG4105Y7M	Transcriptional regulator, TetR family
GTF74_RS13555	ENOG410624X	efflux transporter, rnd family, mfp subunit
GTF74_RS13560	ENOG4105BZS	acriflavin resistance protein
GTF74_RS13565	ENOG4105W0Z	cytoplasmic protein
GTF74_RS13570	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GTF74_RS13575	ENOG4105EMY	transcriptional regulator
GTF74_RS13620	ENOG4108RR8	protoporphyrinogen oxidase
GTF74_RS13625	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GTF74_RS13630	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GTF74_RS13640	ENOG4105CHU	acetyl-coa acetyltransferase
GTF74_RS13645	ENOG4105F52	Transcriptional regulator
GTF74_RS13650	ENOG4105CZQ	inner membrane transport protein YdhC
GTF74_RS13655	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GTF74_RS13660	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GTF74_RS13665	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GTF74_RS13670	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GTF74_RS13675	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GTF74_RS13680	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GTF74_RS13685	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GTF74_RS13695	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GTF74_RS13700	ENOG410684E	atp synthase
GTF74_RS13705	ENOG4105FA0	parb-like partition protein
GTF74_RS13710	ENOG4107QJE	Chromosome Partitioning Protein
GTF74_RS13720	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GTF74_RS13725	ENOG4105QTB	Flavodoxin
GTF74_RS13730	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GTF74_RS13735	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GTF74_RS13745	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GTF74_RS13760	ENOG4105E5Q	amino acid AbC transporter
GTF74_RS13765	ENOG4105EAB	amino acid AbC transporter
GTF74_RS13770	ENOG4106RMF	ParB family
GTF74_RS13800	ENOG4105CDY	transcriptional regulatory protein
GTF74_RS13805	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GTF74_RS13810	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS13815	ENOG4108YYI	Protein of unknown function (DUF2810)
GTF74_RS13820	ENOG41061ZR	Transcriptional regulator
GTF74_RS13825	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GTF74_RS13830	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
GTF74_RS13835	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GTF74_RS13840	ENOG4108WC9	type VI secretion system effector, hcp1 family
GTF74_RS13845	ENOG4105CS6	Rhs element vgr protein
GTF74_RS13870	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GTF74_RS13880	ENOG4105C8P	)-transporter
GTF74_RS13885	ENOG4108Q67	UPF0319 protein
GTF74_RS13905	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS13925	ENOG4105EYK	Phosphatidylglycerophosphatase B
GTF74_RS13930	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
GTF74_RS13955	ENOG4105D6U	Sodium Glutamate Symporter
GTF74_RS13960	ENOG4105YE1	PilZ domain
GTF74_RS13975	ENOG4105EFX	secretion protein, HlyD family
GTF74_RS13980	ENOG4105KK7	inner membrane protein YiaW
GTF74_RS13985	ENOG4106TD9	Diguanylate cyclase
GTF74_RS14000	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GTF74_RS14005	ENOG4107SEY	Conserved Protein
GTF74_RS14015	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GTF74_RS14020	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GTF74_RS14030	ENOG4105C1J	atp-dependent rna helicase
GTF74_RS14035	ENOG4105CUG	Oligopeptidase b
GTF74_RS14065	ENOG4105CVA	phosphate
GTF74_RS14070	ENOG4105C8U	phosphate abc transporter
GTF74_RS14075	ENOG4105E2Z	phosphate ABC transporter (Permease
GTF74_RS14080	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GTF74_RS14085	ENOG4105BZU	Histidine kinase
GTF74_RS14095	ENOG4105DWD	nucleoside recognition domain protein
GTF74_RS14100	ENOG4105CHH	sulfate transporter
GTF74_RS14110	ENOG4105DR5	peptidase
GTF74_RS14115	ENOG4105BZU	Histidine kinase
GTF74_RS14120	ENOG4105EQ2	LysR family Transcriptional regulator
GTF74_RS14125	ENOG4105E5M	Multidrug resistance protein D
GTF74_RS14130	ENOG4108Z4X	TRANSCRIPTIONal
GTF74_RS14145	ENOG4105CK2	sodium dicarboxylate symporter
GTF74_RS14185	ENOG4107RH7	Nicotinate phosphoribosyltransferase
GTF74_RS14190	ENOG4105D9R	oxidoreductase
GTF74_RS14200	ENOG4105BZU	Histidine kinase
GTF74_RS14205	ENOG4107VXZ	Hydrolase
GTF74_RS14215	ENOG4105D3G	Pseudouridine synthase
GTF74_RS14275	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GTF74_RS14280	ENOG4108JUB	Transcriptional regulator
GTF74_RS14305	ENOG4105CS6	Rhs element vgr protein
GTF74_RS14325	ENOG4105C2J	ABC transporter
GTF74_RS14330	ENOG4105CNN	ABC, transporter
GTF74_RS14335	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GTF74_RS14340	ENOG4108RVA	ribokinase
GTF74_RS14345	ENOG4105ETE	Transcriptional regulator (LacI family
GTF74_RS14350	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
GTF74_RS14355	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
GTF74_RS14360	ENOG4108I5U	Uridine phosphorylase
GTF74_RS14370	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
GTF74_RS14375	ENOG4105CXY	transporter
GTF74_RS14390	ENOG4105CQZ	Histidine kinase
GTF74_RS14395	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GTF74_RS14410	ENOG4105D5U	fad dependent oxidoreductase
GTF74_RS14420	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GTF74_RS14430	ENOG4105KJM	monovalent cation h antiporter subunit g
GTF74_RS14435	ENOG41080TA	Multiple resistance and ph regulation protein f
GTF74_RS14440	ENOG4105SC1	monovalent cation H antiporter subunit E
GTF74_RS14445	ENOG4108JPZ	Monovalent cation H antiporter subunit D
GTF74_RS14450	ENOG4105MKQ	Monovalent cation H antiporter subunit C
GTF74_RS14455	ENOG4105D65	subunit l
GTF74_RS14465	ENOG4105Q9Y	Universal stress protein
GTF74_RS14470	ENOG4105CIC	tryptophan-specific transport protein
GTF74_RS14485	ENOG4105VRT	cytoplasmic protein
GTF74_RS14495	ENOG4105BZU	Histidine kinase
GTF74_RS14500	ENOG4105VEQ	Cold shock protein
GTF74_RS14535	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GTF74_RS14540	ENOG41069D7	Methyl-accepting chemotaxis
GTF74_RS14555	ENOG4105D9N	nucleoside
GTF74_RS14560	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GTF74_RS14570	ENOG4108JUA	Transcriptional regulator
GTF74_RS14575	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GTF74_RS14580	ENOG4105VEQ	Cold shock protein
GTF74_RS14600	ENOG4108UNF	response regulator
GTF74_RS14610	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GTF74_RS14615	ENOG4105C5I	Dehydrogenase
GTF74_RS14635	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GTF74_RS14660	ENOG4108RS6	transposase
GTF74_RS14670	ENOG4105C1J	atp-dependent rna helicase
GTF74_RS14675	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GTF74_RS14680	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
GTF74_RS14685	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GTF74_RS14690	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GTF74_RS14695	ENOG4105BZU	Histidine kinase
GTF74_RS14705	ENOG4107S6Z	Na H antiporter
GTF74_RS14710	ENOG4105E5M	Multidrug resistance protein D
GTF74_RS14720	ENOG4105BZU	Histidine kinase
GTF74_RS14725	ENOG4105KUU	lipolytic protein G-D-S-L family
GTF74_RS14730	ENOG4106M3D	hemolysin
GTF74_RS14735	ENOG4108N3W	hemolysin secretion protein
GTF74_RS14740	ENOG4107IFA	Lipase (EC 3.1.1.3)
GTF74_RS14770	ENOG4105DHS	permease protein
GTF74_RS14775	ENOG4105CM4	permease protein
GTF74_RS14780	ENOG4108IPW	abc transporter atp-binding protein
GTF74_RS14800	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GTF74_RS14820	ENOG4105ETX	regulatoR
GTF74_RS14830	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
GTF74_RS14840	ENOG410667J	hydrolase
GTF74_RS14870	ENOG4105DS1	cytochrome b561
GTF74_RS14900	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GTF74_RS14905	ENOG4105BZU	Histidine kinase
GTF74_RS14930	ENOG4107QVI	Methyltransferase, type 11
GTF74_RS14945	ENOG4105C2C	drug resistance transporter, Bcr CflA
GTF74_RS14950	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS14960	ENOG4105DZ1	carboxypeptidase
GTF74_RS14980	ENOG4108RS6	transposase
GTF74_RS14985	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GTF74_RS14990	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GTF74_RS14995	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GTF74_RS15005	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GTF74_RS15015	ENOG4105F2I	Transposase
GTF74_RS15045	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GTF74_RS15050	ENOG41082NX	50s ribosomal protein l35
GTF74_RS15055	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GTF74_RS15110	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GTF74_RS15145	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GTF74_RS15190	ENOG4105D9U	N-acetyltransferase
GTF74_RS15195	ENOG4105QNF	Outer membrane lipoprotein
GTF74_RS15225	ENOG4105VXN	addiction module toxin, RelE StbE family
GTF74_RS15250	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
GTF74_RS15320	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
GTF74_RS15340	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
GTF74_RS15375	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GTF74_RS15395	ENOG4105QNF	Outer membrane lipoprotein
GTF74_RS15410	ENOG4105YGK	Pfam:UPF0157
GTF74_RS15420	ENOG4105N14	lysine exporter protein LysE YggA
GTF74_RS15605	ENOG41080ET	plasmid maintenance system killer protein
GTF74_RS15610	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
GTF74_RS15630	ENOG4108S58	Phenazine biosynthesis protein PhzF
GTF74_RS15660	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GTF74_RS15680	ENOG4105QNF	Outer membrane lipoprotein
GTF74_RS15735	ENOG4105D9U	N-acetyltransferase
GTF74_RS15835	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
GTF74_RS15860	ENOG4105QNF	Outer membrane lipoprotein
GTF74_RS15965	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
GTF74_RS16005	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
GTF74_RS16010	ENOG4105W08	virulence gene repressor rsal
GTF74_RS16025	ENOG4105F2I	Transposase
GTF74_RS16050	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GTF74_RS16135	ENOG4108RS6	transposase
GTF74_RS16200	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GTF74_RS16220	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GTF74_RS16225	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
GTF74_RS16230	ENOG4105CGF	Aromatic amino acid aminotransferase
GTF74_RS16235	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GTF74_RS16240	ENOG4105DM4	PTS System
GTF74_RS16245	ENOG4105DE4	1-phosphofructokinase
GTF74_RS16250	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
GTF74_RS16255	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
GTF74_RS16260	ENOG4107RFY	SbcCD D subunit
GTF74_RS16265	ENOG4105EYH	Exonuclease
GTF74_RS16270	ENOG4108MGY	Histidine kinase
GTF74_RS16275	ENOG4107KBT	8-Amino-7-oxononanoate synthase
GTF74_RS16290	ENOG4105CKI	cobalamin synthesis protein
GTF74_RS16295	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
GTF74_RS16305	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
GTF74_RS16310	ENOG4105C08	Histidine kinase
GTF74_RS16315	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
GTF74_RS16320	ENOG410607N	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity)
GTF74_RS16325	ENOG4108RHM	integral membrane protein
GTF74_RS16335	ENOG4105EPM	Diguanylate phosphodiesterase
GTF74_RS16345	ENOG4105DS1	cytochrome b561
GTF74_RS16355	ENOG4105TMB	Formate nitrite transporter
GTF74_RS16360	ENOG4105DUM	transcriptional regulator, lysR family
GTF74_RS16365	ENOG4108UQ5	membrane protein YcdZ
GTF74_RS16370	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
GTF74_RS16375	ENOG4105CGH	5'-nucleotidase
GTF74_RS16380	ENOG4105DU1	integral membrane protein, terc
GTF74_RS16390	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
GTF74_RS16420	ENOG4105BZU	Histidine kinase
GTF74_RS16430	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GTF74_RS16440	ENOG4105BZU	Histidine kinase
GTF74_RS16455	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GTF74_RS16460	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GTF74_RS16470	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GTF74_RS16490	ENOG4108ZJT	translation initiation factor, Sui1
GTF74_RS16510	ENOG4105CD5	CoA-binding domain protein
GTF74_RS16515	ENOG4105CWB	LysR family transcriptional Regulator
GTF74_RS16535	ENOG4105KA0	thioesterase Superfamily protein
GTF74_RS16555	ENOG4105CYM	Glutathione S-transferase
GTF74_RS16570	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GTF74_RS16575	ENOG4108JQ5	ABC transporter
GTF74_RS16580	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
GTF74_RS16585	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
GTF74_RS16590	ENOG4105E43	Extracellular solute-binding protein, family 5
GTF74_RS16615	ENOG4105DUX	Transporter
GTF74_RS16630	ENOG4107RCV	ABC transporter, permease
GTF74_RS16645	ENOG4107STF	Involved in phosphonate degradation (By similarity)
GTF74_RS16650	ENOG4108JPW	Aminotransferase
GTF74_RS16655	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
GTF74_RS16660	ENOG4105NXH	GreA GreB family elongation factor
GTF74_RS16665	ENOG4105PAD	Hydrolase
GTF74_RS16675	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
GTF74_RS16680	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GTF74_RS16685	ENOG4105CKU	formyltetrahydrofolate synthetase
GTF74_RS16690	ENOG4105E0X	reductase
GTF74_RS16695	ENOG4105EUJ	GTP cyclohydrolase i
GTF74_RS16700	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GTF74_RS16705	ENOG4105D06	uba thif-type nad fad binding protein
GTF74_RS16715	ENOG4105KHC	sulfurtransferase
GTF74_RS16720	ENOG4107RHR	regulatoR
GTF74_RS16730	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GTF74_RS16755	ENOG4108M3J	Dehydrogenase
GTF74_RS16770	ENOG4105RA2	Membrane
GTF74_RS16780	ENOG4105ETT	transcriptional Regulator, LysR family
GTF74_RS16785	ENOG41067V3	Antibiotic biosynthesis monooxygenase
GTF74_RS16790	ENOG4108RCM	Nitroreductase
GTF74_RS16825	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
GTF74_RS16870	ENOG4105C5Y	PTS System
GTF74_RS16875	ENOG4105ETE	Transcriptional regulator (LacI family
GTF74_RS16880	ENOG4107R3K	hydrolase
GTF74_RS16885	ENOG4105D7K	pfkb domain protein
GTF74_RS16890	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GTF74_RS16895	ENOG4108NVR	Methyl-accepting chemotaxis
GTF74_RS16900	ENOG4108ZG0	Ompa motb domain protein
GTF74_RS16905	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GTF74_RS16910	ENOG4107VXZ	Hydrolase
GTF74_RS16915	ENOG4108N3W	hemolysin secretion protein
GTF74_RS16920	ENOG4105CEE	C4-dicarboxylate transporter
GTF74_RS16925	ENOG4105EJQ	L-serine dehydratase
GTF74_RS16945	ENOG4105ETE	Transcriptional regulator (LacI family
GTF74_RS16950	ENOG4105WH1	Two component transcriptional regulator luxr family
GTF74_RS16955	ENOG4105BZU	Histidine kinase
GTF74_RS16970	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GTF74_RS16990	ENOG4105DHT	Metal Dependent Phosphohydrolase
GTF74_RS16995	ENOG4108KX4	response regulator
GTF74_RS17000	ENOG4105BZU	Histidine kinase
GTF74_RS17005	ENOG4105CXY	transporter
GTF74_RS17010	ENOG4105C4Y	ABC transporter
GTF74_RS17015	ENOG4107RCV	ABC transporter, permease
GTF74_RS17020	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GTF74_RS17025	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
GTF74_RS17035	ENOG4105CHU	acetyl-coa acetyltransferase
GTF74_RS17045	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GTF74_RS17050	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GTF74_RS17065	ENOG4105BZU	Histidine kinase
GTF74_RS17070	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GTF74_RS17080	ENOG4108I6A	alcohol dehydrogenase
GTF74_RS17090	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
GTF74_RS17100	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
GTF74_RS17105	ENOG4105CXY	transporter
GTF74_RS17110	ENOG4105CA9	Pyruvate kinase
GTF74_RS17115	ENOG4105BZU	Histidine kinase
GTF74_RS17120	ENOG4108SV3	Tmao reductase system periplasmic protein tort
GTF74_RS17125	ENOG4108Z5K	methylglyoxal synthase
GTF74_RS17130	ENOG4108RWI	nicotinamidase
GTF74_RS17135	ENOG41080IJ	Diacylglycerol kinase
GTF74_RS17150	ENOG41088T4	Helicase IV
GTF74_RS17155	ENOG4105EM2	membrane
GTF74_RS17185	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GTF74_RS17190	ENOG4105E0C	molybdate abc transporter
GTF74_RS17195	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GTF74_RS17200	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GTF74_RS17240	ENOG4105BZU	Histidine kinase
GTF74_RS17245	ENOG4108QGH	periplasmic
GTF74_RS17255	ENOG41082IR	Excinuclease ABC C subunit domain protein
GTF74_RS17270	ENOG41090HJ	UPF0265 protein
GTF74_RS17280	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GTF74_RS17285	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GTF74_RS17290	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
GTF74_RS17295	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
GTF74_RS17300	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GTF74_RS17305	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GTF74_RS17310	ENOG4105K63	Thioredoxin
GTF74_RS17340	ENOG4105DUM	transcriptional regulator, lysR family
GTF74_RS17345	ENOG4105DMR	ABC, transporter
GTF74_RS17350	ENOG4105GBT	ABC transporter
GTF74_RS17355	ENOG4106PMH	Extracellular solute-binding protein family 3
GTF74_RS17360	ENOG4105E5Z	arginine transporter ATP-binding subunit
GTF74_RS17370	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
GTF74_RS17380	ENOG4108YZ4	nudix hydrolase
GTF74_RS17385	ENOG4105C5W	Aldolase
GTF74_RS17390	ENOG4106RE7	Cytochrome
GTF74_RS17395	ENOG4107XI7	Tetr family transcriptional regulator
GTF74_RS17400	ENOG4105C1J	atp-dependent rna helicase
GTF74_RS17405	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
GTF74_RS17410	ENOG4105E0U	tyrosine-specific transport protein
GTF74_RS17415	ENOG4108N3W	hemolysin secretion protein
GTF74_RS17420	ENOG4105CMR	udp-glucose 4-epimerase
GTF74_RS17425	ENOG4105E7W	lamb ycsf family protein
GTF74_RS17435	ENOG4107R7A	Allophanate hydrolase subunit 2
GTF74_RS17445	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GTF74_RS17450	ENOG4105CV6	ABC transporter, permease
GTF74_RS17455	ENOG4108I0Y	(ABC) transporter
GTF74_RS17465	ENOG4105RKW	reductase (By
GTF74_RS17480	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GTF74_RS17520	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GTF74_RS17535	ENOG4107RE1	Inosine-guanosine kinase
GTF74_RS17540	ENOG4105E0M	Sulfatase
GTF74_RS17550	ENOG4105C1J	atp-dependent rna helicase
GTF74_RS17565	ENOG4105CVA	phosphate
GTF74_RS17575	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
GTF74_RS17580	ENOG4108M1A	Chitin-binding protein
GTF74_RS17585	ENOG4105D4Y	metalloprotease
GTF74_RS17595	ENOG4105CYW	agmatinase
GTF74_RS17600	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GTF74_RS17610	ENOG4105CJW	magnesium transporter
GTF74_RS17615	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GTF74_RS17620	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GTF74_RS17630	ENOG4105CZK	Aspartate kinase
GTF74_RS17635	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
GTF74_RS17640	ENOG4108JPW	Aminotransferase
GTF74_RS17645	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
GTF74_RS17655	ENOG4105MIR	Phenylalanine 4-monooxygenase
GTF74_RS17660	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GTF74_RS17675	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GTF74_RS17680	ENOG4105EGI	Transcriptional regulator
GTF74_RS17700	ENOG4105C37	(CBS) domain
GTF74_RS17705	ENOG4108UKZ	OsmC family
GTF74_RS17710	ENOG4107YWA	deoxycytidylate deaminase
GTF74_RS17730	ENOG4105DVH	amino acid
GTF74_RS17735	ENOG4106TD9	Diguanylate cyclase
GTF74_RS17745	ENOG4108VAC	response regulator
GTF74_RS17750	ENOG4108HRK	Histidine kinase
GTF74_RS17765	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GTF74_RS17770	ENOG4105C19	ABC transporter
GTF74_RS17780	ENOG4107RGM	aldo keto reductase
GTF74_RS17785	ENOG4107T9C	Alpha amylase catalytic region
GTF74_RS17795	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GTF74_RS17800	ENOG4108M0H	Extracellular lipase
GTF74_RS17805	ENOG4107SDU	Methyl-accepting chemotaxis
GTF74_RS17810	ENOG4105D4Y	metalloprotease
GTF74_RS17820	ENOG4105EIF	outer membrane protein W
GTF74_RS17830	ENOG41061WM	D-Alanyl-D-Alanine
GTF74_RS17835	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GTF74_RS17840	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GTF74_RS17845	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GTF74_RS17860	ENOG4105BZC	d-serine deaminase
GTF74_RS17865	ENOG4105W8I	Transcriptional regulator
GTF74_RS17910	ENOG4105CPQ	Dehydrogenase
GTF74_RS17915	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GTF74_RS17930	ENOG4105EXG	Transcriptional regulator
GTF74_RS17935	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
GTF74_RS17955	ENOG4107SSZ	Phosphatase
GTF74_RS17960	ENOG4105DHT	Metal Dependent Phosphohydrolase
GTF74_RS17965	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GTF74_RS17970	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
GTF74_RS17975	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GTF74_RS18000	ENOG4105BZW	Glycerate kinase
GTF74_RS18005	ENOG4105C6Z	Gluconate
GTF74_RS18010	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
GTF74_RS18015	ENOG4108NVR	Methyl-accepting chemotaxis
GTF74_RS18020	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
GTF74_RS18025	ENOG41090JE	Utilization Protein
GTF74_RS18030	ENOG4105D4P	Coproporphyrinogen iii oxidase
GTF74_RS18035	ENOG4105WQ5	TonB family
GTF74_RS18040	ENOG41090AP	transport protein
GTF74_RS18045	ENOG4106GFD	transport protein
GTF74_RS18050	ENOG4107R4I	Periplasmic binding protein
GTF74_RS18055	ENOG4105EHG	Permease protein
GTF74_RS18060	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GTF74_RS18090	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS18095	ENOG4105QVC	MOSC domain-containing protein
GTF74_RS18095	ENOG4105QVC	MOSC domain-containing protein
GTF74_RS18100	ENOG4105EKE	dihydroorotase
GTF74_RS18110	ENOG4105KAF	membrAne
GTF74_RS18120	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
GTF74_RS18125	ENOG4105CKW	Inner membrane protein yedI
GTF74_RS18130	ENOG4108ESY	Metal dependent phosphohydrolase
GTF74_RS18135	ENOG4105VEQ	Cold shock protein
GTF74_RS18160	ENOG4105BZU	Histidine kinase
GTF74_RS18165	ENOG4105E98	transcriptional regulator DeoR family
GTF74_RS18180	ENOG4105EG2	ABC transporter, permease
GTF74_RS18185	ENOG4105D56	permease protein
GTF74_RS18190	ENOG4107FKK	extracellular solute-binding protein family 1
GTF74_RS18195	ENOG4108IJ9	(ABC) transporter
GTF74_RS18200	ENOG4108HK0	-acetyltransferase
GTF74_RS18215	ENOG4105K8R	UPF0145 protein
GTF74_RS18220	ENOG41086KC	Transcriptional regulator
GTF74_RS18225	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
GTF74_RS18235	ENOG4105K56	Transcriptional regulator
GTF74_RS18240	ENOG4106TD9	Diguanylate cyclase
GTF74_RS18255	ENOG4105BZU	Histidine kinase
GTF74_RS18275	ENOG4105ETT	transcriptional Regulator, LysR family
GTF74_RS18280	ENOG4108K0B	C-di-gmp phosphodiesterase
GTF74_RS18290	ENOG4105EUB	pirin domain protein
GTF74_RS18295	ENOG4105NBK	UPF0345 protein
GTF74_RS18305	ENOG4105E5W	Transporter
GTF74_RS18310	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS18315	ENOG4105DAN	ATP-dependent protease
GTF74_RS18325	ENOG4108JQ5	ABC transporter
GTF74_RS18330	ENOG4105E89	ABC transporter
GTF74_RS18335	ENOG4107SDU	Methyl-accepting chemotaxis
GTF74_RS18350	ENOG4105CC0	LysR family Transcriptional regulator
GTF74_RS18360	ENOG4105DAA	L-lactate
GTF74_RS18375	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GTF74_RS18385	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GTF74_RS18395	ENOG4105C1J	atp-dependent rna helicase
GTF74_RS18400	ENOG4105CR8	Transcriptional regulator
GTF74_RS18410	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GTF74_RS18420	ENOG4105BZ1	(ABC) transporter
GTF74_RS18430	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GTF74_RS18440	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
GTF74_RS18465	ENOG4105K56	Transcriptional regulator
GTF74_RS18470	ENOG4108ZHJ	Organic hydroperoxide resistance protein
GTF74_RS18480	ENOG4108SXK	Transporter Drug Metabolite Exporter family
GTF74_RS18485	ENOG4105VW4	glutaredoxin 3
GTF74_RS18490	ENOG4108P2H	Inner membrane protein YjiG
GTF74_RS18495	ENOG41074DU	domain protein
GTF74_RS18500	ENOG4105DN9	Na H antiporter
GTF74_RS18510	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GTF74_RS18515	ENOG4105D03	DNA-3-methyladenine glycosylase II
GTF74_RS18520	ENOG4108VGI	doxx family
GTF74_RS18545	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GTF74_RS18555	ENOG4107W52	maltose operon periplasmic protein
GTF74_RS18560	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
GTF74_RS18575	ENOG4108N3W	hemolysin secretion protein
GTF74_RS18590	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS18600	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GTF74_RS18605	ENOG4105CDA	abc transporter atp-binding protein
GTF74_RS18615	ENOG4106TNF	Periplasmic binding protein
GTF74_RS18620	ENOG4105EZ7	amino acid ABC transporter
GTF74_RS18625	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
GTF74_RS18635	ENOG4105DR5	peptidase
GTF74_RS18640	ENOG4105CTS	PTS system mannitol-specific
GTF74_RS18645	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
GTF74_RS18650	ENOG4105E61	Mannitol repressor protein
GTF74_RS18655	ENOG4105EP9	oxidoreductase
GTF74_RS18685	ENOG4108RYK	Nad-dependent epimerase dehydratase
GTF74_RS18690	ENOG4105JQN	Transcriptional regulator
GTF74_RS18695	ENOG41069D7	Methyl-accepting chemotaxis
GTF74_RS18700	ENOG4105EMU	Dehydrogenase
GTF74_RS18705	ENOG4105JQN	Transcriptional regulator
GTF74_RS18725	ENOG4105D5Q	Arginine ornithine antiporter
GTF74_RS18730	ENOG4105CXN	decarboxylase
GTF74_RS18740	ENOG4107RGH	Aldehyde dehydrogenase
GTF74_RS18745	ENOG4105EW9	transcriptional regulator AsnC family
GTF74_RS18750	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS18760	ENOG4105CK7	Sodium proline symporter
GTF74_RS18770	ENOG4105C26	Dehydrogenase
GTF74_RS18785	ENOG4105E6M	Sulphatase-modifying factor protein
GTF74_RS18800	ENOG4107QZV	Type I secretion membrane fusion protein
GTF74_RS18815	ENOG4108JJA	ABC, transporter
GTF74_RS18825	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GTF74_RS18835	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS18840	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GTF74_RS18850	ENOG4105BZU	Histidine kinase
GTF74_RS18855	ENOG4105C8Q	Methyl-accepting chemotaxis
GTF74_RS18860	ENOG4108V3W	Chemotaxis protein, CheW
GTF74_RS18865	ENOG4108V3W	Chemotaxis protein, CheW
GTF74_RS18870	ENOG4105CBS	Chea signal transduction histidine kinase
GTF74_RS18875	ENOG4108VYJ	response regulator receiver protein
GTF74_RS18890	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GTF74_RS18895	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GTF74_RS18900	ENOG4108JQ6	ABC transporter
GTF74_RS18905	ENOG4105DIJ	Phosphoethanolamine transferase
GTF74_RS18910	ENOG4105DHQ	Histidine kinase
GTF74_RS18915	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GTF74_RS18945	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
GTF74_RS18950	ENOG4107RUE	extracellular solute-binding protein family 1