locus-tag	class	description
GTF71_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GTF71_RS00010	COG0592	DNA-directed DNA polymerase activity
GTF71_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GTF71_RS00020	COG0187	DNA topoisomerase II activity
GTF71_RS00030	COG0071	Belongs to the small heat shock protein (HSP20) family
GTF71_RS00035	COG3977	Valine--pyruvate aminotransferase
GTF71_RS00040	COG0751	glycine-tRNA ligase activity
GTF71_RS00045	COG0752	glycyl-tRNA synthetase alpha subunit
GTF71_RS00050	COG2119	membrane
GTF71_RS00060	COG0425	Belongs to the sulfur carrier protein TusA family
GTF71_RS00070	COG0604	alcohol dehydrogenase
GTF71_RS00080	COG0129	dihydroxy-acid dehydratase activity
GTF71_RS00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GTF71_RS00100	COG0606	chelatase, subunit chli
GTF71_RS00105	COG0204	Acyl-transferase
GTF71_RS00110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GTF71_RS00115	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GTF71_RS00125	COG3084	Protein conserved in bacteria
GTF71_RS00130	COG4326	sporulation control protein
GTF71_RS00135	COG1272	protein, Hemolysin III
GTF71_RS00145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GTF71_RS00150	COG0569	domain protein
GTF71_RS00155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GTF71_RS00155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GTF71_RS00160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GTF71_RS00165	COG0242	peptide deformylase activity
GTF71_RS00170	COG1652	LysM domain
GTF71_RS00175	COG0758	DNA mediated transformation
GTF71_RS00180	COG2922	Belongs to the Smg family
GTF71_RS00185	COG0551	DNA topoisomerase type I activity
GTF71_RS00190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GTF71_RS00195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GTF71_RS00200	COG0009	L-threonylcarbamoyladenylate synthase
GTF71_RS00205	COG0408	coproporphyrinogen oxidase activity
GTF71_RS00210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GTF71_RS00220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GTF71_RS00260	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GTF71_RS00265	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GTF71_RS00275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GTF71_RS00280	COG2104	thiamine diphosphate biosynthetic process
GTF71_RS00285	COG2022	thiamine diphosphate biosynthetic process
GTF71_RS00290	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GTF71_RS00295	COG0006	proline dipeptidase activity
GTF71_RS00295	COG0006	proline dipeptidase activity
GTF71_RS00315	COG1522	sequence-specific DNA binding
GTF71_RS00320	COG5001	Diguanylate cyclase
GTF71_RS00320	COG5002	protein histidine kinase activity
GTF71_RS00340	COG0589	response to stress
GTF71_RS00345	COG1528	Iron-storage protein
GTF71_RS00355	COG2081	HI0933 family
GTF71_RS00365	COG1322	Protein conserved in bacteria
GTF71_RS00370	COG2226	methyltransferase
GTF71_RS00385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GTF71_RS00390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GTF71_RS00395	COG0805	protein transport
GTF71_RS00400	COG1858	cytochrome C peroxidase
GTF71_RS00405	COG0534	Mate efflux family protein
GTF71_RS00415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GTF71_RS00425	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GTF71_RS00430	COG3161	chorismate lyase activity
GTF71_RS00435	COG1580	Controls the rotational direction of flagella during chemotaxis
GTF71_RS00440	COG0840	transmembrane signaling receptor activity
GTF71_RS00450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GTF71_RS00455	COG0084	hydrolase, TatD family'
GTF71_RS00470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GTF71_RS00470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GTF71_RS00490	COG3078	GTPase activator activity
GTF71_RS00505	COG3071	HemY protein
GTF71_RS00510	COG2959	enzyme of heme biosynthesis
GTF71_RS00515	COG1587	Uroporphyrinogen-III synthase
GTF71_RS00520	COG0181	hydroxymethylbilane synthase activity
GTF71_RS00530	COG1965	Belongs to the frataxin family
GTF71_RS00540	COG0019	diaminopimelate decarboxylase activity
GTF71_RS00545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GTF71_RS00555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GTF71_RS00560	COG1011	Hydrolase
GTF71_RS00565	COG2199	diguanylate cyclase activity
GTF71_RS00565	COG2200	EAL domain
GTF71_RS00565	COG3287	FIST C domain
GTF71_RS00580	COG0561	phosphatase activity
GTF71_RS00585	COG2267	carboxylic ester hydrolase activity
GTF71_RS00590	COG1280	lysine exporter protein (LysE YggA)
GTF71_RS00595	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GTF71_RS00600	COG0783	Belongs to the Dps family
GTF71_RS00630	COG0742	ribosomal rna small subunit methyltransferase
GTF71_RS00635	COG0552	protein localization to endoplasmic reticulum
GTF71_RS00640	COG2884	Cell division ATP-binding protein ftsE
GTF71_RS00645	COG2177	Part of the ABC transporter FtsEX involved in
GTF71_RS00650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GTF71_RS00655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTF71_RS00670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GTF71_RS00675	COG4206	TonB-dependent receptor
GTF71_RS00680	COG1404	Belongs to the peptidase S8 family
GTF71_RS00685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GTF71_RS00720	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GTF71_RS00725	COG5001	Diguanylate cyclase
GTF71_RS00725	COG3300	MHYT domain
GTF71_RS00735	COG3852	Histidine kinase
GTF71_RS00745	COG0174	glutamine synthetase
GTF71_RS00765	COG1295	ribonuclease BN
GTF71_RS00770	COG1490	D-aminoacyl-tRNA deacylase activity
GTF71_RS00775	COG0456	acetyltransferase
GTF71_RS00785	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GTF71_RS00790	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GTF71_RS00795	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GTF71_RS00800	COG3031	protein transport across the cell outer membrane
GTF71_RS00810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GTF71_RS00815	COG1459	type II secretion system
GTF71_RS00820	COG2165	general secretion pathway protein
GTF71_RS00825	COG2165	general secretion pathway protein
GTF71_RS00830	COG2165	general secretion pathway protein
GTF71_RS00835	COG4795	General secretion pathway protein
GTF71_RS00840	COG3156	type II secretion system protein K
GTF71_RS00845	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GTF71_RS00850	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GTF71_RS00860	COG1218	3'(2'),5'-bisphosphate nucleotidase
GTF71_RS00865	COG0494	nUDIX hydrolase
GTF71_RS00875	COG1040	competence protein
GTF71_RS00885	COG0596	Alpha beta hydrolase
GTF71_RS00895	COG2183	response to ionizing radiation
GTF71_RS00900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GTF71_RS00905	COG0745	RESPONSE REGULATOR receiver
GTF71_RS00915	COG2233	PERMEase
GTF71_RS00920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GTF71_RS00925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GTF71_RS00930	COG1758	RNA polymerase activity
GTF71_RS00935	COG0194	GDP metabolic process
GTF71_RS00940	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GTF71_RS00945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GTF71_RS00965	COG4232	protein-disulfide reductase activity
GTF71_RS00975	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GTF71_RS00980	COG1027	Aspartate ammonia-lyase
GTF71_RS00985	COG3706	GGDEF domain
GTF71_RS00990	COG3030	protein affecting phage T7 exclusion by the F plasmid
GTF71_RS00995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GTF71_RS01005	COG2205	protein histidine kinase activity
GTF71_RS01010	COG0745	RESPONSE REGULATOR receiver
GTF71_RS01020	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GTF71_RS01025	COG0205	6-phosphofructokinase activity
GTF71_RS01030	COG1494	fructose-1,6-bisphosphatase
GTF71_RS01035	COG3074	FtsZ-dependent cytokinesis
GTF71_RS01040	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GTF71_RS01045	COG0460	homoserine dehydrogenase
GTF71_RS01045	COG0527	aspartate kinase activity
GTF71_RS01050	COG0626	cystathionine gamma-synthase activity
GTF71_RS01055	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
GTF71_RS01060	COG0281	malic enzyme
GTF71_RS01065	COG0254	rRNA binding
GTF71_RS01070	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GTF71_RS01075	COG1609	Transcriptional regulator
GTF71_RS01080	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GTF71_RS01085	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GTF71_RS01090	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GTF71_RS01095	COG1575	Belongs to the MenA family. Type 1 subfamily
GTF71_RS01100	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GTF71_RS01105	COG0534	Mate efflux family protein
GTF71_RS01110	COG0149	triose-phosphate isomerase activity
GTF71_RS01135	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GTF71_RS01140	COG0459	protein refolding
GTF71_RS01150	COG1509	lysine 2,3-aminomutase activity
GTF71_RS01155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GTF71_RS01165	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GTF71_RS01170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GTF71_RS01175	COG1053	succinate dehydrogenase
GTF71_RS01180	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GTF71_RS01185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GTF71_RS01190	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GTF71_RS01195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GTF71_RS01200	COG1045	serine acetyltransferase
GTF71_RS01210	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GTF71_RS01215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GTF71_RS01220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GTF71_RS01225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GTF71_RS01230	COG0137	argininosuccinate synthase activity
GTF71_RS01235	COG0165	Argininosuccinate lyase
GTF71_RS01245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTF71_RS01250	COG0678	peroxiredoxin activity
GTF71_RS01250	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GTF71_RS01260	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GTF71_RS01290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GTF71_RS01295	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GTF71_RS01305	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GTF71_RS01310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GTF71_RS01315	COG0546	phosphoglycolate phosphatase activity
GTF71_RS01320	COG0180	Tryptophanyl-tRNA synthetase
GTF71_RS01335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GTF71_RS01345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GTF71_RS01355	COG1012	belongs to the aldehyde dehydrogenase family
GTF71_RS01370	COG3954	Phosphoribulokinase
GTF71_RS01380	COG0429	hydrolase of the alpha beta-hydrolase fold
GTF71_RS01390	COG0488	(ABC) transporter
GTF71_RS01395	COG2249	NAD(P)H dehydrogenase (quinone) activity
GTF71_RS01410	COG1047	Peptidyl-prolyl cis-trans
GTF71_RS01425	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GTF71_RS01430	COG3083	sulfuric ester hydrolase activity
GTF71_RS01435	COG0557	exoribonuclease II activity
GTF71_RS01440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GTF71_RS01445	COG0051	transcription antitermination factor activity, RNA binding
GTF71_RS01450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GTF71_RS01455	COG0088	Forms part of the polypeptide exit tunnel
GTF71_RS01460	COG0089	rRNA binding
GTF71_RS01465	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GTF71_RS01470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GTF71_RS01475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GTF71_RS01480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GTF71_RS01485	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GTF71_RS01490	COG0255	Belongs to the universal ribosomal protein uL29 family
GTF71_RS01495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GTF71_RS01500	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GTF71_RS01505	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GTF71_RS01510	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GTF71_RS01515	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GTF71_RS01520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GTF71_RS01530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GTF71_RS01535	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GTF71_RS01540	COG1841	ribosomal large subunit assembly
GTF71_RS01550	COG0201	protein transport
GTF71_RS01555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GTF71_RS01560	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GTF71_RS01565	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GTF71_RS01570	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GTF71_RS01575	COG0202	RNA polymerase activity
GTF71_RS01580	COG0203	ribosomal protein L17
GTF71_RS01590	COG0545	Peptidyl-prolyl cis-trans isomerase
GTF71_RS01595	COG3266	domain, Protein
GTF71_RS01595	COG3061	Opacity-associated protein A
GTF71_RS01600	COG0697	spore germination
GTF71_RS01605	COG2153	protein acetylation
GTF71_RS01610	COG0513	Belongs to the DEAD box helicase family
GTF71_RS01620	COG0737	Belongs to the 5'-nucleotidase family
GTF71_RS01625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GTF71_RS01625	COG1648	precorrin-2 dehydrogenase activity
GTF71_RS01640	COG0529	Catalyzes the synthesis of activated sulfate
GTF71_RS01660	COG1136	(ABC) transporter
GTF71_RS01675	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GTF71_RS01680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GTF71_RS01685	COG0729	surface antigen
GTF71_RS01695	COG2105	PFAM AIG2 family protein
GTF71_RS01700	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GTF71_RS01710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GTF71_RS01715	COG0163	prenyltransferase activity
GTF71_RS01725	COG1178	ABC-type Fe3 transport system permease component
GTF71_RS01730	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GTF71_RS01735	COG3028	Belongs to the UPF0307 family
GTF71_RS01740	COG0312	modulator of DNA gyrase
GTF71_RS01745	COG2239	Acts as a magnesium transporter
GTF71_RS01750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTF71_RS01755	COG1660	Displays ATPase and GTPase activities
GTF71_RS01760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTF71_RS01765	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GTF71_RS01775	COG1137	ATPase activity
GTF71_RS01780	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GTF71_RS01795	COG0517	IMP dehydrogenase activity
GTF71_RS01795	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GTF71_RS01805	COG1127	ABC transporter
GTF71_RS01810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GTF71_RS01815	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GTF71_RS01820	COG2854	intermembrane phospholipid transfer
GTF71_RS01830	COG5007	Belongs to the BolA IbaG family
GTF71_RS01835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GTF71_RS01845	COG0251	oxidation-reduction process
GTF71_RS01855	COG0540	Belongs to the ATCase OTCase family
GTF71_RS01865	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GTF71_RS01875	COG0564	pseudouridine synthase activity
GTF71_RS01880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GTF71_RS01885	COG0525	valine-tRNA ligase activity
GTF71_RS01890	COG2927	DNA polymerase III (CHI subunit)
GTF71_RS01895	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GTF71_RS01900	COG0795	lipopolysaccharide-transporting ATPase activity
GTF71_RS01905	COG0795	lipopolysaccharide-transporting ATPase activity
GTF71_RS01920	COG3437	response regulator, receiver
GTF71_RS01965	COG0066	3-isopropylmalate dehydratase activity
GTF71_RS01970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GTF71_RS01975	COG0473	3-isopropylmalate dehydrogenase activity
GTF71_RS02000	COG0583	DNA-binding transcription factor activity
GTF71_RS02005	COG1022	Amp-dependent synthetase and ligase
GTF71_RS02010	COG0028	Belongs to the TPP enzyme family
GTF71_RS02015	COG0440	acetolactate synthase activity
GTF71_RS02020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GTF71_RS02025	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GTF71_RS02030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GTF71_RS02040	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GTF71_RS02045	COG3079	Belongs to the UPF0149 family
GTF71_RS02050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTF71_RS02055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTF71_RS02070	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GTF71_RS02080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GTF71_RS02085	COG1595	DNA-templated transcription, initiation
GTF71_RS02100	COG3086	response to oxidative stress
GTF71_RS02105	COG0481	GTPase activity
GTF71_RS02120	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GTF71_RS02125	COG1381	Involved in DNA repair and RecF pathway recombination
GTF71_RS02130	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GTF71_RS02150	COG5001	Diguanylate cyclase
GTF71_RS02165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GTF71_RS02170	COG3956	TIGRFAM MazG family protein
GTF71_RS02175	COG0504	CTP synthase activity
GTF71_RS02180	COG0148	phosphopyruvate hydratase activity
GTF71_RS02190	COG3409	Peptidoglycan-binding domain 1 protein
GTF71_RS02190	COG3267	Type II secretory pathway component ExeA
GTF71_RS02200	COG4991	sh3 domain protein
GTF71_RS02205	COG0306	phosphate transporter
GTF71_RS02210	COG1392	Phosphate transport regulator
GTF71_RS02215	COG3025	triphosphatase activity
GTF71_RS02220	COG0840	transmembrane signaling receptor activity
GTF71_RS02225	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GTF71_RS02235	COG1538	Outer membrane efflux protein
GTF71_RS02240	COG0494	nUDIX hydrolase
GTF71_RS02245	COG3151	Protein conserved in bacteria
GTF71_RS02255	COG3150	esterase
GTF71_RS02260	COG0187	DNA topoisomerase II activity
GTF71_RS02265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GTF71_RS02275	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GTF71_RS02280	COG0237	dephospho-CoA kinase activity
GTF71_RS02290	COG1459	type II secretion system
GTF71_RS02295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GTF71_RS02315	COG0716	FMN binding
GTF71_RS02320	COG4974	Belongs to the 'phage' integrase family
GTF71_RS02325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GTF71_RS02330	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GTF71_RS02335	COG0737	Belongs to the 5'-nucleotidase family
GTF71_RS02340	COG2186	Transcriptional regulator
GTF71_RS02345	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GTF71_RS02350	COG0508	dehydrogenase complex catalyzes the overall conversion of
GTF71_RS02355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTF71_RS02370	COG3116	cell division
GTF71_RS02375	COG0768	penicillin binding
GTF71_RS02380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GTF71_RS02385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GTF71_RS02395	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GTF71_RS02400	COG0772	Belongs to the SEDS family
GTF71_RS02410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GTF71_RS02415	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GTF71_RS02420	COG0849	cell division
GTF71_RS02425	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GTF71_RS02430	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GTF71_RS02440	COG0653	protein targeting
GTF71_RS02445	COG0494	nUDIX hydrolase
GTF71_RS02450	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GTF71_RS02460	COG0505	Belongs to the CarA family
GTF71_RS02465	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GTF71_RS02480	COG4172	Belongs to the ABC transporter superfamily
GTF71_RS02490	COG0730	response to heat
GTF71_RS02495	COG0583	DNA-binding transcription factor activity
GTF71_RS02500	COG2860	membrane
GTF71_RS02505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GTF71_RS02515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GTF71_RS02525	COG0493	'glutamate synthase
GTF71_RS02530	COG0069	glutamate synthase activity
GTF71_RS02530	COG0067	glutamate synthase
GTF71_RS02530	COG0070	glutamate synthase
GTF71_RS02540	COG0070	glutamate synthase
GTF71_RS02540	COG0067	glutamate synthase
GTF71_RS02540	COG0069	glutamate synthase activity
GTF71_RS02545	COG1242	4 iron, 4 sulfur cluster binding
GTF71_RS02550	COG4251	negative regulation of phosphorylation
GTF71_RS02550	COG3706	GGDEF domain
GTF71_RS02550	COG2203	Gaf domain
GTF71_RS02550	COG5001	Diguanylate cyclase
GTF71_RS02555	COG0784	Response regulator, receiver
GTF71_RS02555	COG2198	Histidine kinase
GTF71_RS02555	COG5002	protein histidine kinase activity
GTF71_RS02560	COG0745	RESPONSE REGULATOR receiver
GTF71_RS02570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GTF71_RS02595	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GTF71_RS02600	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
GTF71_RS02605	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GTF71_RS02610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GTF71_RS02625	COG1115	amino acid carrier protein
GTF71_RS02630	COG3022	response to hydroperoxide
GTF71_RS02640	COG0084	hydrolase, TatD family'
GTF71_RS02645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GTF71_RS02655	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GTF71_RS02660	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GTF71_RS02665	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GTF71_RS02670	COG0813	purine-nucleoside phosphorylase activity
GTF71_RS02680	COG0560	Phosphoserine phosphatase
GTF71_RS02690	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GTF71_RS02695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GTF71_RS02700	COG1022	Amp-dependent synthetase and ligase
GTF71_RS02715	COG3250	beta-galactosidase activity
GTF71_RS02720	COG1609	Transcriptional regulator
GTF71_RS02725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GTF71_RS02740	COG0569	domain protein
GTF71_RS02740	COG0189	ligase activity
GTF71_RS02745	COG0456	acetyltransferase
GTF71_RS02755	COG2171	N-acyltransferase activity
GTF71_RS02760	COG3141	response to X-ray
GTF71_RS02775	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GTF71_RS02780	COG1074	ATP-dependent DNA helicase activity
GTF71_RS02785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GTF71_RS02795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GTF71_RS02795	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GTF71_RS02805	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GTF71_RS02810	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GTF71_RS02815	COG2166	iron-sulfur cluster assembly
GTF71_RS02820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GTF71_RS02825	COG0693	protein deglycase activity
GTF71_RS02830	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GTF71_RS02835	COG3248	Nucleoside-binding outer membrane protein
GTF71_RS02845	COG1595	DNA-templated transcription, initiation
GTF71_RS02855	COG2211	Major facilitator Superfamily
GTF71_RS02860	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GTF71_RS02870	COG2813	Specifically methylates the guanine in position
GTF71_RS02875	COG0271	Belongs to the BolA IbaG family
GTF71_RS02880	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GTF71_RS02885	COG1805	sodium ion transport
GTF71_RS02890	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GTF71_RS02895	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GTF71_RS02900	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GTF71_RS02905	COG2871	sodium ion transport
GTF71_RS02910	COG1477	protein flavinylation
GTF71_RS02930	COG3706	GGDEF domain
GTF71_RS02935	COG0733	neurotransmitter:sodium symporter activity
GTF71_RS02945	COG0189	ligase activity
GTF71_RS02950	COG4067	protein conserved in archaea
GTF71_RS02950	COG0189	ligase activity
GTF71_RS02955	COG2195	Cleaves the N-terminal amino acid of tripeptides
GTF71_RS02960	COG2252	PERMEase
GTF71_RS02965	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GTF71_RS02980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GTF71_RS02985	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GTF71_RS02990	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GTF71_RS02995	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GTF71_RS02995	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GTF71_RS03010	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GTF71_RS03015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GTF71_RS03020	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GTF71_RS03025	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GTF71_RS03035	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GTF71_RS03040	COG0024	Methionine aminopeptidase
GTF71_RS03045	COG0052	Belongs to the universal ribosomal protein uS2 family
GTF71_RS03050	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GTF71_RS03055	COG0528	UMP kinase activity
GTF71_RS03060	COG0233	cytoplasmic translational termination
GTF71_RS03065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GTF71_RS03070	COG0575	Belongs to the CDS family
GTF71_RS03075	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GTF71_RS03080	COG0750	zinc metalloprotease
GTF71_RS03090	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GTF71_RS03095	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GTF71_RS03100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GTF71_RS03105	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GTF71_RS03110	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GTF71_RS03115	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GTF71_RS03120	COG0587	DNA-directed DNA polymerase activity
GTF71_RS03125	COG0825	malonyl-CoA metabolic process
GTF71_RS03130	COG0037	tRNA processing
GTF71_RS03140	COG3479	Phenolic acid decarboxylase
GTF71_RS03145	COG0347	Belongs to the P(II) protein family
GTF71_RS03150	COG3021	interspecies interaction between organisms
GTF71_RS03155	COG0741	lytic transglycosylase activity
GTF71_RS03155	COG1388	LysM domain
GTF71_RS03160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GTF71_RS03165	COG2226	methyltransferase
GTF71_RS03170	COG0328	RNA-DNA hybrid ribonuclease activity
GTF71_RS03185	COG1960	acyl-CoA dehydrogenase activity
GTF71_RS03190	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GTF71_RS03195	COG0121	glutamine amidotransferase
GTF71_RS03200	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GTF71_RS03205	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GTF71_RS03210	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GTF71_RS03215	COG3706	GGDEF domain
GTF71_RS03220	COG1187	pseudouridine synthase activity
GTF71_RS03225	COG2840	Smr protein MutS2
GTF71_RS03240	COG3735	TraB family
GTF71_RS03255	COG2217	Heavy metal translocating P-type atpase
GTF71_RS03255	COG2608	mercury ion transmembrane transporter activity
GTF71_RS03260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GTF71_RS03275	COG4774	siderophore transport
GTF71_RS03275	COG1629	transport
GTF71_RS03280	COG2375	cellular response to nickel ion
GTF71_RS03285	COG2226	methyltransferase
GTF71_RS03285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GTF71_RS03285	COG3433	isochorismatase activity
GTF71_RS03320	COG0784	Response regulator, receiver
GTF71_RS03320	COG0835	chemotaxis
GTF71_RS03325	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GTF71_RS03330	COG1815	bacterial-type flagellum-dependent cell motility
GTF71_RS03345	COG1749	Flagellar hook protein flgE
GTF71_RS03350	COG4787	bacterial-type flagellum-dependent cell motility
GTF71_RS03360	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GTF71_RS03365	COG1706	bacterial-type flagellum-dependent cell motility
GTF71_RS03370	COG3951	Flagellar rod assembly protein muramidase FlgJ
GTF71_RS03370	COG1705	Flagellar rod assembly protein muramidase FlgJ
GTF71_RS03385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GTF71_RS03390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GTF71_RS03475	COG0012	GTP binding
GTF71_RS03480	COG0193	aminoacyl-tRNA hydrolase activity
GTF71_RS03485	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GTF71_RS03490	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GTF71_RS03495	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GTF71_RS03500	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GTF71_RS03505	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GTF71_RS03510	COG2890	protein-(glutamine-N5) methyltransferase activity
GTF71_RS03520	COG2912	Transglutaminase-like superfamily
GTF71_RS03525	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GTF71_RS03530	COG0737	Belongs to the 5'-nucleotidase family
GTF71_RS03535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GTF71_RS03540	COG2233	PERMEase
GTF71_RS03560	COG1393	Belongs to the ArsC family
GTF71_RS03565	COG4783	chaperone-mediated protein folding
GTF71_RS03580	COG0840	transmembrane signaling receptor activity
GTF71_RS03585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GTF71_RS03600	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GTF71_RS03610	COG1876	peptidase activity
GTF71_RS03620	COG1393	Belongs to the ArsC family
GTF71_RS03640	COG2837	iron assimilation
GTF71_RS03645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GTF71_RS03650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GTF71_RS03655	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GTF71_RS03660	COG1334	flagellar protein FlaG
GTF71_RS03665	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GTF71_RS03675	COG1516	flagellar protein fliS
GTF71_RS03685	COG4191	Histidine kinase
GTF71_RS03695	COG1677	Flagellar hook-basal body complex protein FliE
GTF71_RS03705	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GTF71_RS03710	COG1317	bacterial-type flagellum organization
GTF71_RS03735	COG1580	Controls the rotational direction of flagella during chemotaxis
GTF71_RS03760	COG1987	bacterial-type flagellum assembly
GTF71_RS03765	COG1684	flagellar biosynthetic protein fliR
GTF71_RS03775	COG2840	Smr protein MutS2
GTF71_RS03780	COG2890	protein-(glutamine-N5) methyltransferase activity
GTF71_RS03785	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GTF71_RS03790	COG2860	membrane
GTF71_RS03795	COG3101	peptidyl-lysine hydroxylation
GTF71_RS03805	COG0431	NADPH-dependent FMN reductase
GTF71_RS03815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GTF71_RS03820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GTF71_RS03825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GTF71_RS03830	COG0735	belongs to the Fur family
GTF71_RS03840	COG0583	DNA-binding transcription factor activity
GTF71_RS03850	COG1346	cytolysis
GTF71_RS03865	COG0596	Alpha beta hydrolase
GTF71_RS03870	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GTF71_RS03875	COG0033	Phosphoglucomutase
GTF71_RS03885	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GTF71_RS03890	COG0372	Belongs to the citrate synthase family
GTF71_RS03895	COG2009	succinate dehydrogenase
GTF71_RS03900	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GTF71_RS03905	COG1053	succinate dehydrogenase
GTF71_RS03915	COG0567	Dehydrogenase, E1 component
GTF71_RS03920	COG0508	dehydrogenase complex catalyzes the overall conversion of
GTF71_RS03925	COG0045	succinate-CoA ligase (ADP-forming) activity
GTF71_RS03935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GTF71_RS03940	COG1121	(ABC) transporter
GTF71_RS03945	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GTF71_RS03950	COG4977	sequence-specific DNA binding
GTF71_RS03955	COG1918	ferrous iron import across plasma membrane
GTF71_RS03975	COG0018	arginyl-trna synthetase
GTF71_RS03990	COG2062	phosphohistidine phosphatase, SixA
GTF71_RS04020	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GTF71_RS04025	COG2198	Histidine kinase
GTF71_RS04025	COG0643	Histidine kinase
GTF71_RS04025	COG0784	Response regulator, receiver
GTF71_RS04030	COG2201	protein-glutamate methylesterase activity
GTF71_RS04035	COG1192	Involved in chromosome partitioning
GTF71_RS04045	COG0835	chemotaxis
GTF71_RS04055	COG4133	protoheme IX ABC transporter activity
GTF71_RS04060	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GTF71_RS04065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GTF71_RS04075	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GTF71_RS04080	COG1138	Cytochrome C-type biogenesis protein
GTF71_RS04085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GTF71_RS04090	COG4235	cytochrome complex assembly
GTF71_RS04090	COG3088	subunit of a heme lyase
GTF71_RS04100	COG2853	Lipoprotein
GTF71_RS04120	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GTF71_RS04125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GTF71_RS04130	COG0123	including yeast histone deacetylase and acetoin utilization protein
GTF71_RS04150	COG3082	Protein of unknown function (DUF1414)
GTF71_RS04155	COG3081	Nucleoid-associated protein
GTF71_RS04165	COG1757	Na H antiporter
GTF71_RS04170	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GTF71_RS04175	COG2095	MarC family integral membrane protein
GTF71_RS04180	COG1012	belongs to the aldehyde dehydrogenase family
GTF71_RS04180	COG1454	alcohol dehydrogenase
GTF71_RS04190	COG0659	secondary active sulfate transmembrane transporter activity
GTF71_RS04195	COG1530	ribonuclease E activity
GTF71_RS04200	COG0564	pseudouridine synthase activity
GTF71_RS04205	COG0424	maF-like protein
GTF71_RS04210	COG1399	metal-binding, possibly nucleic acid-binding protein
GTF71_RS04215	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GTF71_RS04220	COG0416	fatty acid biosynthetic process
GTF71_RS04225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GTF71_RS04235	COG1028	Short-chain dehydrogenase reductase Sdr
GTF71_RS04240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GTF71_RS04245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GTF71_RS04250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GTF71_RS04255	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GTF71_RS04260	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GTF71_RS04270	COG0084	hydrolase, TatD family'
GTF71_RS04275	COG1263	PTS System
GTF71_RS04275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTF71_RS04285	COG0733	neurotransmitter:sodium symporter activity
GTF71_RS04300	COG4667	esterase of the alpha-beta hydrolase superfamily
GTF71_RS04310	COG1940	carbohydrate kinase activity
GTF71_RS04315	COG0835	chemotaxis
GTF71_RS04315	COG0784	Response regulator, receiver
GTF71_RS04330	COG2226	methyltransferase
GTF71_RS04340	COG0676	glucose-6-phosphate 1-epimerase activity
GTF71_RS04345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GTF71_RS04350	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GTF71_RS04360	COG3139	Protein of unknown function (DUF1315)
GTF71_RS04365	COG0252	asparaginase activity
GTF71_RS04370	COG0616	signal peptide processing
GTF71_RS04375	COG0446	pyridine nucleotide-disulphide oxidoreductase
GTF71_RS04375	COG1902	pentaerythritol trinitrate reductase activity
GTF71_RS04380	COG0788	formyltetrahydrofolate deformylase activity
GTF71_RS04390	COG1199	ATP-dependent helicase activity
GTF71_RS04395	COG1214	PFAM Peptidase M22, glycoprotease
GTF71_RS04410	COG0596	Alpha beta hydrolase
GTF71_RS04415	COG0318	PFAM AMP-dependent synthetase and ligase
GTF71_RS04420	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GTF71_RS04440	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GTF71_RS04445	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GTF71_RS04450	COG0436	Aminotransferase
GTF71_RS04455	COG1169	isochorismate synthase
GTF71_RS04460	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GTF71_RS04465	COG0596	Alpha beta hydrolase
GTF71_RS04485	COG3135	benzoate transporter
GTF71_RS04490	COG1396	sequence-specific DNA binding
GTF71_RS04495	COG0840	transmembrane signaling receptor activity
GTF71_RS04505	COG0477	Major facilitator Superfamily
GTF71_RS04525	COG3015	lipoprotein NlpE involved in copper resistance
GTF71_RS04530	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GTF71_RS04535	COG2894	cell division
GTF71_RS04540	COG0850	regulation of cytokinetic process
GTF71_RS04545	COG3100	YcgL domain-containing protein
GTF71_RS04550	COG2951	lytic endotransglycosylase activity
GTF71_RS04560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GTF71_RS04565	COG3325	Belongs to the glycosyl hydrolase 18 family
GTF71_RS04565	COG3469	chitinase activity
GTF71_RS04570	COG3005	denitrification pathway
GTF71_RS04575	COG0243	molybdopterin cofactor binding
GTF71_RS04590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTF71_RS04600	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GTF71_RS04635	COG4589	Belongs to the CDS family
GTF71_RS04645	COG5001	Diguanylate cyclase
GTF71_RS04645	COG3300	MHYT domain
GTF71_RS04655	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GTF71_RS04660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GTF71_RS04665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GTF71_RS04670	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GTF71_RS04680	COG4191	Histidine kinase
GTF71_RS04690	COG0544	peptidyl-prolyl cis-trans isomerase activity
GTF71_RS04700	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GTF71_RS04705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GTF71_RS04710	COG0776	regulation of translation
GTF71_RS04715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTF71_RS04720	COG1555	photosystem II stabilization
GTF71_RS04725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GTF71_RS04730	COG0539	negative regulation of cytoplasmic translation
GTF71_RS04735	COG0776	regulation of translation
GTF71_RS04740	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GTF71_RS04745	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GTF71_RS04765	COG0583	DNA-binding transcription factor activity
GTF71_RS04775	COG0686	Belongs to the AlaDH PNT family
GTF71_RS04785	COG1674	ftsk spoiiie
GTF71_RS04790	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GTF71_RS04795	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GTF71_RS04800	COG2186	Transcriptional regulator
GTF71_RS04815	COG0537	adenosine 5'-monophosphoramidase activity
GTF71_RS04840	COG3150	esterase
GTF71_RS04845	COG1252	NADH dehydrogenase
GTF71_RS04865	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GTF71_RS04875	COG4591	ABC-type transport system involved in lipoprotein release permease component
GTF71_RS04880	COG1136	(ABC) transporter
GTF71_RS04885	COG4591	ABC-type transport system involved in lipoprotein release permease component
GTF71_RS04895	COG2333	competence protein COMEC
GTF71_RS04895	COG0658	competence protein
GTF71_RS04900	COG1132	(ABC) transporter
GTF71_RS04905	COG1663	tetraacyldisaccharide 4'-kinase activity
GTF71_RS04910	COG2835	tetraacyldisaccharide 4'-kinase activity
GTF71_RS04915	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GTF71_RS04920	COG2719	SpoVR family
GTF71_RS04925	COG2718	Belongs to the UPF0229 family
GTF71_RS04930	COG2766	serine protein kinase
GTF71_RS04935	COG3013	Belongs to the UPF0304 family
GTF71_RS04945	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GTF71_RS04950	COG0840	transmembrane signaling receptor activity
GTF71_RS04960	COG1882	Formate acetyltransferase
GTF71_RS04985	COG4160	amino acid transport
GTF71_RS04990	COG0708	Exodeoxyribonuclease III
GTF71_RS04995	COG0840	transmembrane signaling receptor activity
GTF71_RS05005	COG3923	Primosomal replication protein n
GTF71_RS05010	COG0730	response to heat
GTF71_RS05015	COG1199	ATP-dependent helicase activity
GTF71_RS05020	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTF71_RS05025	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GTF71_RS05030	COG3012	SEC-C Motif Domain Protein
GTF71_RS05035	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GTF71_RS05040	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GTF71_RS05045	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GTF71_RS05050	COG0215	cysteine-tRNA ligase activity
GTF71_RS05055	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GTF71_RS05060	COG0632	four-way junction helicase activity
GTF71_RS05070	COG1271	oxidase subunit
GTF71_RS05075	COG1294	oxidase, subunit
GTF71_RS05080	COG4890	Cyd operon protein YbgT
GTF71_RS05085	COG3790	cyd operon protein YbgE
GTF71_RS05090	COG0824	Thioesterase
GTF71_RS05095	COG0811	peptide transport
GTF71_RS05110	COG0823	Involved in the tonB-independent uptake of proteins
GTF71_RS05115	COG2885	chlorophyll binding
GTF71_RS05120	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GTF71_RS05125	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GTF71_RS05135	COG0784	Response regulator, receiver
GTF71_RS05135	COG5002	protein histidine kinase activity
GTF71_RS05145	COG1482	cell wall glycoprotein biosynthetic process
GTF71_RS05150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTF71_RS05150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTF71_RS05150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTF71_RS05155	COG2207	Transcriptional regulator
GTF71_RS05165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTF71_RS05170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTF71_RS05175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTF71_RS05185	COG1012	belongs to the aldehyde dehydrogenase family
GTF71_RS05190	COG3284	Transcriptional regulator
GTF71_RS05195	COG4628	conserved protein (DUF2132)
GTF71_RS05205	COG0415	Belongs to the DNA photolyase family
GTF71_RS05285	COG0488	(ABC) transporter
GTF71_RS05325	COG3941	tape measure
GTF71_RS05340	COG2003	Belongs to the UPF0758 family
GTF71_RS05350	COG4409	exo-alpha-(2->6)-sialidase activity
GTF71_RS05355	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GTF71_RS05360	COG1940	carbohydrate kinase activity
GTF71_RS05370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GTF71_RS05375	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GTF71_RS05380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GTF71_RS05385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GTF71_RS05390	COG1737	Transcriptional regulator
GTF71_RS05395	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
GTF71_RS05400	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
GTF71_RS05420	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GTF71_RS05440	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GTF71_RS05460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GTF71_RS05465	COG0582	viral genome integration into host DNA
GTF71_RS05470	COG0582	viral genome integration into host DNA
GTF71_RS05485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTF71_RS05495	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GTF71_RS05495	COG3008	intermembrane lipid transfer
GTF71_RS05500	COG2995	paraquat-inducible protein a
GTF71_RS05505	COG0668	transmembrane transport
GTF71_RS05525	COG1309	transcriptional regulator
GTF71_RS05530	COG1012	belongs to the aldehyde dehydrogenase family
GTF71_RS05560	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GTF71_RS05565	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GTF71_RS05590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GTF71_RS05595	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GTF71_RS05600	COG0297	glycogen (starch) synthase activity
GTF71_RS05620	COG3070	regulator of competence-specific genes
GTF71_RS05625	COG1609	Transcriptional regulator
GTF71_RS05630	COG3381	protein complex oligomerization
GTF71_RS05635	COG0745	RESPONSE REGULATOR receiver
GTF71_RS05640	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GTF71_RS05645	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GTF71_RS05655	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GTF71_RS05675	COG1032	radical SAM domain protein
GTF71_RS05680	COG5001	Diguanylate cyclase
GTF71_RS05685	COG0612	Peptidase, M16
GTF71_RS05700	COG0583	DNA-binding transcription factor activity
GTF71_RS05705	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GTF71_RS05715	COG2350	Protein conserved in bacteria
GTF71_RS05720	COG1607	acyl-coa hydrolase
GTF71_RS05735	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GTF71_RS05740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GTF71_RS05750	COG2116	formate transmembrane transporter activity
GTF71_RS05760	COG4459	periplasmic nitrate reductase
GTF71_RS05765	COG3005	denitrification pathway
GTF71_RS05770	COG0243	molybdopterin cofactor binding
GTF71_RS05790	COG1227	inorganic diphosphatase activity
GTF71_RS05805	COG4172	Belongs to the ABC transporter superfamily
GTF71_RS05820	COG4168	peptide transport system, permease
GTF71_RS05830	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GTF71_RS05835	COG1842	Phage shock protein A
GTF71_RS05850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTF71_RS05865	COG2818	Glycosylase
GTF71_RS05870	COG0626	cystathionine gamma-synthase activity
GTF71_RS05880	COG0733	neurotransmitter:sodium symporter activity
GTF71_RS05885	COG0564	pseudouridine synthase activity
GTF71_RS05890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GTF71_RS05895	COG4136	ATPase activity
GTF71_RS05900	COG4135	transport system, permease component
GTF71_RS05905	COG4134	Bacterial extracellular solute-binding protein
GTF71_RS05915	COG3313	Fe-S protein
GTF71_RS05925	COG0842	Transport permease protein
GTF71_RS05930	COG1131	(ABC) transporter
GTF71_RS05935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTF71_RS05940	COG0814	amino acid
GTF71_RS05950	COG2239	Acts as a magnesium transporter
GTF71_RS05955	COG0784	Response regulator, receiver
GTF71_RS05955	COG2205	protein histidine kinase activity
GTF71_RS05970	COG4934	collagen metabolic process
GTF71_RS06000	COG0840	transmembrane signaling receptor activity
GTF71_RS06010	COG3706	GGDEF domain
GTF71_RS06010	COG2203	Gaf domain
GTF71_RS06010	COG5001	Diguanylate cyclase
GTF71_RS06010	COG4251	negative regulation of phosphorylation
GTF71_RS06015	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GTF71_RS06035	COG1061	Type III restriction enzyme res subunit
GTF71_RS06040	COG1187	pseudouridine synthase activity
GTF71_RS06045	COG2814	Major facilitator Superfamily
GTF71_RS06055	COG0702	epimerase
GTF71_RS06060	COG0534	Mate efflux family protein
GTF71_RS06065	COG4181	ATPase activity
GTF71_RS06080	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GTF71_RS06090	COG1748	Saccharopine dehydrogenase
GTF71_RS06105	COG1538	Outer membrane efflux protein
GTF71_RS06125	COG0583	DNA-binding transcription factor activity
GTF71_RS06135	COG1451	nucleotide metabolic process
GTF71_RS06140	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GTF71_RS06150	COG3063	Type IV pilus biogenesis stability protein PilW
GTF71_RS06155	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GTF71_RS06175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTF71_RS06190	COG3290	protein histidine kinase activity
GTF71_RS06195	COG4565	transcriptional regulatory protein
GTF71_RS06205	COG0784	Response regulator, receiver
GTF71_RS06205	COG0835	chemotaxis
GTF71_RS06250	COG1085	galactose-1-phosphate uridylyltransferase
GTF71_RS06255	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GTF71_RS06260	COG2017	converts alpha-aldose to the beta-anomer
GTF71_RS06265	COG3706	GGDEF domain
GTF71_RS06270	COG2200	EAL domain
GTF71_RS06270	COG2199	diguanylate cyclase activity
GTF71_RS06285	COG3527	Alpha-acetolactate decarboxylase
GTF71_RS06300	COG0753	catalase activity
GTF71_RS06320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GTF71_RS06330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GTF71_RS06370	COG1271	oxidase subunit
GTF71_RS06375	COG1294	oxidase, subunit
GTF71_RS06380	COG1136	(ABC) transporter
GTF71_RS06380	COG4591	ABC-type transport system involved in lipoprotein release permease component
GTF71_RS06385	COG0577	efflux transmembrane transporter activity
GTF71_RS06385	COG1136	(ABC) transporter
GTF71_RS06390	COG1136	(ABC) transporter
GTF71_RS06390	COG0577	efflux transmembrane transporter activity
GTF71_RS06410	COG0583	DNA-binding transcription factor activity
GTF71_RS06420	COG2723	6-phospho-beta-galactosidase activity
GTF71_RS06425	COG1609	Transcriptional regulator
GTF71_RS06430	COG0251	oxidation-reduction process
GTF71_RS06435	COG2731	YhcH YjgK YiaL family protein
GTF71_RS06440	COG0584	glycerophosphoryl diester phosphodiesterase
GTF71_RS06445	COG1349	DNA-binding transcription factor activity
GTF71_RS06450	COG3842	ATPase activity
GTF71_RS06455	COG0395	ABC-type sugar transport system, permease component
GTF71_RS06460	COG1175	transmembrane transport
GTF71_RS06475	COG0811	peptide transport
GTF71_RS06480	COG0811	peptide transport
GTF71_RS06485	COG0848	biopolymer transport protein
GTF71_RS06490	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GTF71_RS06500	COG1793	dna ligase
GTF71_RS06510	COG0534	Mate efflux family protein
GTF71_RS06520	COG3001	Fructosamine kinase
GTF71_RS06530	COG0791	NLP P60 protein
GTF71_RS06535	COG0840	transmembrane signaling receptor activity
GTF71_RS06550	COG1940	carbohydrate kinase activity
GTF71_RS06575	COG0746	molybdenum cofactor guanylyltransferase activity
GTF71_RS06580	COG3842	ATPase activity
GTF71_RS06585	COG4662	Binding-protein-dependent transport system inner membrane component
GTF71_RS06595	COG2204	response regulator
GTF71_RS06600	COG3852	Histidine kinase
GTF71_RS06605	COG0488	(ABC) transporter
GTF71_RS06610	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GTF71_RS06640	COG3383	formate dehydrogenase (NAD+) activity
GTF71_RS06640	COG0243	molybdopterin cofactor binding
GTF71_RS06645	COG0437	4 iron, 4 sulfur cluster binding
GTF71_RS06660	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GTF71_RS06665	COG1666	GTP binding
GTF71_RS06670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GTF71_RS06685	COG2996	Protein conserved in bacteria
GTF71_RS06695	COG3008	intermembrane lipid transfer
GTF71_RS06700	COG2995	paraquat-inducible protein a
GTF71_RS06705	COG1132	(ABC) transporter
GTF71_RS06710	COG1956	GAF domain-containing protein
GTF71_RS06715	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GTF71_RS06730	COG0308	aminopeptidase N
GTF71_RS06745	COG0167	dihydroorotate dehydrogenase activity
GTF71_RS06755	COG0116	Belongs to the methyltransferase superfamily
GTF71_RS06755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GTF71_RS06780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GTF71_RS06785	COG1067	ATP-dependent peptidase activity
GTF71_RS06790	COG3120	sequence-specific DNA binding
GTF71_RS06865	COG1476	TRANSCRIPTIONal
GTF71_RS06885	COG1476	TRANSCRIPTIONal
GTF71_RS06915	COG4128	Pfam Zonular occludens toxin
GTF71_RS06930	COG1476	TRANSCRIPTIONal
GTF71_RS06950	COG3064	Membrane
GTF71_RS06950	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GTF71_RS06950	COG1073	alpha beta
GTF71_RS06955	COG2994	toxin metabolic process
GTF71_RS06980	COG0784	Response regulator, receiver
GTF71_RS06980	COG2205	protein histidine kinase activity
GTF71_RS06995	COG3278	Belongs to the heme-copper respiratory oxidase family
GTF71_RS07010	COG2010	Cytochrome c
GTF71_RS07020	COG2217	Heavy metal translocating P-type atpase
GTF71_RS07035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GTF71_RS07040	COG0589	response to stress
GTF71_RS07065	COG3842	ATPase activity
GTF71_RS07075	COG1177	transmembrane transport
GTF71_RS07085	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GTF71_RS07100	COG1115	amino acid carrier protein
GTF71_RS07105	COG1280	lysine exporter protein (LysE YggA)
GTF71_RS07130	COG3501	Rhs element vgr protein
GTF71_RS07140	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GTF71_RS07150	COG2814	Major facilitator Superfamily
GTF71_RS07155	COG1566	PFAM secretion protein HlyD family protein
GTF71_RS07160	COG1538	Outer membrane efflux protein
GTF71_RS07170	COG0513	Belongs to the DEAD box helicase family
GTF71_RS07180	COG0840	transmembrane signaling receptor activity
GTF71_RS07185	COG0840	transmembrane signaling receptor activity
GTF71_RS07185	COG3290	protein histidine kinase activity
GTF71_RS07190	COG0835	chemotaxis
GTF71_RS07195	COG2201	protein-glutamate methylesterase activity
GTF71_RS07205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GTF71_RS07210	COG2198	Histidine kinase
GTF71_RS07210	COG0784	Response regulator, receiver
GTF71_RS07210	COG0643	Histidine kinase
GTF71_RS07215	COG2198	Histidine kinase
GTF71_RS07215	COG0643	Histidine kinase
GTF71_RS07225	COG0745	RESPONSE REGULATOR receiver
GTF71_RS07240	COG0415	Belongs to the DNA photolyase family
GTF71_RS07245	COG0477	Major facilitator Superfamily
GTF71_RS07250	COG0583	DNA-binding transcription factor activity
GTF71_RS07260	COG0095	Lipoate-protein ligase
GTF71_RS07265	COG0443	Heat shock 70 kDa protein
GTF71_RS07275	COG1643	Atp-dependent helicase
GTF71_RS07305	COG0443	Heat shock 70 kDa protein
GTF71_RS07310	COG0443	Heat shock 70 kDa protein
GTF71_RS07315	COG3706	GGDEF domain
GTF71_RS07345	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GTF71_RS07350	COG0602	queuosine metabolic process
GTF71_RS07355	COG0561	phosphatase activity
GTF71_RS07365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTF71_RS07370	COG4597	amino acid ABC transporter
GTF71_RS07375	COG0765	amino acid transport
GTF71_RS07380	COG1126	abc transporter atp-binding protein
GTF71_RS07385	COG0670	Belongs to the BI1 family
GTF71_RS07390	COG2920	part of a sulfur-relay system
GTF71_RS07395	COG1254	Belongs to the acylphosphatase family
GTF71_RS07400	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GTF71_RS07405	COG3706	GGDEF domain
GTF71_RS07420	COG3437	response regulator, receiver
GTF71_RS07425	COG0625	glutathione transferase activity
GTF71_RS07435	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GTF71_RS07445	COG2195	Cleaves the N-terminal amino acid of tripeptides
GTF71_RS07475	COG0372	Belongs to the citrate synthase family
GTF71_RS07480	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GTF71_RS07520	COG1129	ABC transporter
GTF71_RS07545	COG0745	RESPONSE REGULATOR receiver
GTF71_RS07550	COG2205	protein histidine kinase activity
GTF71_RS07555	COG3713	MltA-interacting MipA family protein
GTF71_RS07560	COG2990	Protein conserved in bacteria
GTF71_RS07570	COG4191	Histidine kinase
GTF71_RS07570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTF71_RS07575	COG0471	metal ion transport
GTF71_RS07585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GTF71_RS07600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTF71_RS07610	COG3768	UPF0283 membrane protein
GTF71_RS07615	COG3106	COG3106 Predicted ATPase
GTF71_RS07630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GTF71_RS07635	COG0494	nUDIX hydrolase
GTF71_RS07640	COG0814	amino acid
GTF71_RS07645	COG1760	l-serine dehydratase
GTF71_RS07650	COG0720	synthase
GTF71_RS07660	COG0017	Asparaginyl-tRNA synthetase
GTF71_RS07665	COG0351	phosphomethylpyrimidine kinase
GTF71_RS07670	COG3437	response regulator, receiver
GTF71_RS07670	COG2770	Histidine kinase
GTF71_RS07675	COG1448	Aminotransferase
GTF71_RS07690	COG0840	transmembrane signaling receptor activity
GTF71_RS07695	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GTF71_RS07700	COG2943	transferase activity, transferring hexosyl groups
GTF71_RS07705	COG1609	Transcriptional regulator
GTF71_RS07715	COG1486	melibiose metabolic process
GTF71_RS07720	COG1447	Phosphotransferase system cellobiose-specific component IIA
GTF71_RS07730	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GTF71_RS07735	COG0726	polysaccharide deacetylase
GTF71_RS07740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GTF71_RS07745	COG1846	Transcriptional regulator
GTF71_RS07770	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GTF71_RS07785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GTF71_RS07790	COG3108	Peptidase M15
GTF71_RS07795	COG2989	Protein conserved in bacteria
GTF71_RS07820	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GTF71_RS07830	COG2814	Major facilitator Superfamily
GTF71_RS07850	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GTF71_RS07855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GTF71_RS07860	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GTF71_RS07910	COG4139	cobalamin transport
GTF71_RS07930	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GTF71_RS07935	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GTF71_RS07940	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GTF71_RS07950	COG2925	Exonuclease
GTF71_RS07955	COG1380	Effector of murein hydrolase LrgA
GTF71_RS07960	COG1346	cytolysis
GTF71_RS07990	COG0776	regulation of translation
GTF71_RS07995	COG0072	phenylalanine-tRNA ligase activity
GTF71_RS07995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GTF71_RS08000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GTF71_RS08040	COG0322	excinuclease ABC activity
GTF71_RS08045	COG2197	response regulator
GTF71_RS08050	COG0417	DNA replication proofreading
GTF71_RS08055	COG5001	Diguanylate cyclase
GTF71_RS08065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GTF71_RS08070	COG3099	Belongs to the UPF0263 family
GTF71_RS08085	COG1228	amidohydrolase
GTF71_RS08090	COG0010	Belongs to the arginase family
GTF71_RS08095	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GTF71_RS08100	COG2986	histidine ammonia-lyase
GTF71_RS08120	COG0277	FAD linked oxidase domain protein
GTF71_RS08120	COG0247	lactate metabolic process
GTF71_RS08135	COG2885	chlorophyll binding
GTF71_RS08155	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GTF71_RS08165	COG0281	malic enzyme
GTF71_RS08175	COG2949	membrane
GTF71_RS08185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GTF71_RS08195	COG0492	ferredoxin-NADP+ reductase activity
GTF71_RS08200	COG4988	ABC transporter
GTF71_RS08205	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GTF71_RS08210	COG1187	pseudouridine synthase activity
GTF71_RS08215	COG0009	L-threonylcarbamoyladenylate synthase
GTF71_RS08220	COG0613	PHP domain protein
GTF71_RS08230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GTF71_RS08235	COG0512	Glutamine amidotransferase of anthranilate synthase
GTF71_RS08240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GTF71_RS08245	COG0134	indole-3-glycerol-phosphate synthase activity
GTF71_RS08245	COG0135	phosphoribosylanthranilate isomerase activity
GTF71_RS08250	COG0133	tryptophan synthase activity
GTF71_RS08255	COG0159	tryptophan synthase activity
GTF71_RS08265	COG1435	thymidine kinase activity
GTF71_RS08270	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GTF71_RS08275	COG1801	Protein of unknown function DUF72
GTF71_RS08280	COG4106	trans-aconitate 2-methyltransferase activity
GTF71_RS08285	COG0500	methyltransferase
GTF71_RS08290	COG0189	ligase activity
GTF71_RS08290	COG4067	protein conserved in archaea
GTF71_RS08305	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GTF71_RS08315	COG3852	Histidine kinase
GTF71_RS08330	COG3070	regulator of competence-specific genes
GTF71_RS08340	COG2431	L-lysine efflux transmembrane transporter activity
GTF71_RS08350	COG0076	glutamate decarboxylase activity
GTF71_RS08355	COG1737	Transcriptional regulator
GTF71_RS08360	COG1454	alcohol dehydrogenase
GTF71_RS08360	COG1012	belongs to the aldehyde dehydrogenase family
GTF71_RS08365	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GTF71_RS08370	COG2985	domain, Protein
GTF71_RS08370	COG3273	potassium ion transport
GTF71_RS08375	COG0542	response to heat
GTF71_RS08380	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GTF71_RS08385	COG1278	Cold shock
GTF71_RS08395	COG1187	pseudouridine synthase activity
GTF71_RS08400	COG0140	phosphoribosyl-ATP diphosphatase activity
GTF71_RS08400	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GTF71_RS08405	COG0107	imidazoleglycerol-phosphate synthase activity
GTF71_RS08410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GTF71_RS08415	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GTF71_RS08420	COG0131	Imidazoleglycerol-phosphate dehydratase
GTF71_RS08420	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GTF71_RS08425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GTF71_RS08430	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GTF71_RS08435	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GTF71_RS08440	COG1757	Na H antiporter
GTF71_RS08445	COG2916	Histone family protein nucleoid-structuring protein H-NS
GTF71_RS08450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTF71_RS08455	COG0482	sulfurtransferase activity
GTF71_RS08460	COG2915	High frequency lysogenization protein hflD homolog
GTF71_RS08465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GTF71_RS08475	COG2268	Band 7 protein
GTF71_RS08485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GTF71_RS08500	COG0300	oxidoreductase activity
GTF71_RS08510	COG0501	Belongs to the peptidase M48B family
GTF71_RS08520	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GTF71_RS08525	COG2226	methyltransferase
GTF71_RS08530	COG0156	8-amino-7-oxononanoate synthase activity
GTF71_RS08535	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GTF71_RS08540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GTF71_RS08545	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GTF71_RS08550	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GTF71_RS08555	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GTF71_RS08565	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GTF71_RS08570	COG2203	Gaf domain
GTF71_RS08570	COG2199	diguanylate cyclase activity
GTF71_RS08580	COG4120	Belongs to the binding-protein-dependent transport system permease family
GTF71_RS08590	COG4628	conserved protein (DUF2132)
GTF71_RS08595	COG3092	negative regulation of chromosome organization
GTF71_RS08600	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GTF71_RS08605	COG0857	belongs to the CobB CobQ family
GTF71_RS08605	COG0280	phosphate acetyltransferase
GTF71_RS08610	COG0435	Glutathione S-transferase
GTF71_RS08615	COG4608	Belongs to the ABC transporter superfamily
GTF71_RS08620	COG0444	Belongs to the ABC transporter superfamily
GTF71_RS08625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTF71_RS08630	COG0601	transmembrane transport
GTF71_RS08650	COG2204	response regulator
GTF71_RS08655	COG3300	MHYT domain
GTF71_RS08655	COG5001	Diguanylate cyclase
GTF71_RS08660	COG4191	Histidine kinase
GTF71_RS08665	COG5002	protein histidine kinase activity
GTF71_RS08675	COG2201	protein-glutamate methylesterase activity
GTF71_RS08690	COG0009	L-threonylcarbamoyladenylate synthase
GTF71_RS08705	COG1881	PFAM PEBP family protein
GTF71_RS08730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GTF71_RS08735	COG0640	Transcriptional regulator
GTF71_RS08745	COG3706	GGDEF domain
GTF71_RS08765	COG1946	Acyl-CoA thioesterase
GTF71_RS08770	COG1522	sequence-specific DNA binding
GTF71_RS08780	COG0616	signal peptide processing
GTF71_RS08785	COG1028	Short-chain dehydrogenase reductase Sdr
GTF71_RS08790	COG2983	Belongs to the UPF0260 family
GTF71_RS08800	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GTF71_RS08805	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GTF71_RS08815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GTF71_RS08820	COG2832	Protein of unknown function (DUF454)
GTF71_RS08825	COG0745	RESPONSE REGULATOR receiver
GTF71_RS08830	COG0583	DNA-binding transcription factor activity
GTF71_RS08835	COG0778	Nitroreductase
GTF71_RS08840	COG1250	3-hydroxyacyl-CoA dehydrogenase
GTF71_RS08840	COG1024	Enoyl-CoA hydratase
GTF71_RS08845	COG0183	Belongs to the thiolase family
GTF71_RS08860	COG2067	long-chain fatty acid transport protein
GTF71_RS08870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GTF71_RS08875	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GTF71_RS08880	COG2982	Protein involved in outer membrane biogenesis
GTF71_RS08885	COG0572	uridine kinase
GTF71_RS08890	COG0489	protein tyrosine kinase activity
GTF71_RS08895	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GTF71_RS08895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GTF71_RS08905	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GTF71_RS08915	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GTF71_RS08915	COG0617	tRNA 3'-terminal CCA addition
GTF71_RS08915	COG0517	IMP dehydrogenase activity
GTF71_RS08920	COG2199	diguanylate cyclase activity
GTF71_RS08925	COG0314	molybdopterin synthase activity
GTF71_RS08930	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GTF71_RS08935	COG0315	cyclic pyranopterin monophosphate synthase activity
GTF71_RS08940	COG0521	Mo-molybdopterin cofactor biosynthetic process
GTF71_RS08945	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GTF71_RS08950	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GTF71_RS08955	COG2198	Histidine kinase
GTF71_RS08960	COG2204	response regulator
GTF71_RS08965	COG0556	nucleotide-excision repair
GTF71_RS08975	COG4657	Part of a membrane complex involved in electron transport
GTF71_RS08980	COG2878	Part of a membrane complex involved in electron transport
GTF71_RS08985	COG4656	Part of a membrane complex involved in electron transport
GTF71_RS09005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GTF71_RS09010	COG0346	lactoylglutathione lyase activity
GTF71_RS09025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GTF71_RS09030	COG2056	Na+-H+ antiporter family
GTF71_RS09035	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GTF71_RS09040	COG1286	toxin biosynthetic process
GTF71_RS09045	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GTF71_RS09050	COG0285	dihydrofolate synthase activity
GTF71_RS09055	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GTF71_RS09060	COG0101	tRNA pseudouridine synthase activity
GTF71_RS09075	COG2190	(PTS) system
GTF71_RS09075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTF71_RS09075	COG1263	PTS System
GTF71_RS09080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GTF71_RS09085	COG1846	Transcriptional regulator
GTF71_RS09085	COG1940	carbohydrate kinase activity
GTF71_RS09090	COG4651	solute:proton antiporter activity
GTF71_RS09090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GTF71_RS09095	COG0367	asparagine synthase
GTF71_RS09110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GTF71_RS09115	COG0563	adenylate kinase activity
GTF71_RS09120	COG0326	Molecular chaperone. Has ATPase activity
GTF71_RS09125	COG3710	Transcriptional regulator
GTF71_RS09140	COG0622	Phosphoesterase
GTF71_RS09145	COG1090	epimerase
GTF71_RS09150	COG0300	oxidoreductase activity
GTF71_RS09155	COG3118	belongs to the thioredoxin family
GTF71_RS09160	COG0330	HflC and HflK could
GTF71_RS09165	COG1585	Membrane protein implicated in regulation of membrane protease activity
GTF71_RS09170	COG0789	Transcriptional regulator
GTF71_RS09185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GTF71_RS09190	COG3115	cell septum assembly
GTF71_RS09195	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GTF71_RS09200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GTF71_RS09205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTF71_RS09215	COG2190	(PTS) system
GTF71_RS09220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GTF71_RS09225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GTF71_RS09230	COG1702	phosphate starvation-inducible protein PhoH
GTF71_RS09240	COG4535	Mg2 and Co2 transporter CorC
GTF71_RS09245	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GTF71_RS09250	COG2888	peptidyl-tyrosine sulfation
GTF71_RS09255	COG0495	leucyl-tRNA aminoacylation
GTF71_RS09260	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GTF71_RS09265	COG1466	dna polymerase III delta subunit
GTF71_RS09270	COG0799	negative regulation of ribosome biogenesis
GTF71_RS09275	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GTF71_RS09280	COG0768	penicillin binding
GTF71_RS09285	COG0772	Belongs to the SEDS family
GTF71_RS09290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GTF71_RS09295	COG1686	Belongs to the peptidase S11 family
GTF71_RS09300	COG2921	Belongs to the UPF0250 family
GTF71_RS09305	COG0321	lipoyl(octanoyl) transferase activity
GTF71_RS09310	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GTF71_RS09320	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GTF71_RS09345	COG1596	polysaccharide export
GTF71_RS09355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GTF71_RS09385	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GTF71_RS09395	COG0438	transferase activity, transferring glycosyl groups
GTF71_RS09405	COG1045	serine acetyltransferase
GTF71_RS09425	COG0110	maltose O-acetyltransferase activity
GTF71_RS09430	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GTF71_RS09435	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GTF71_RS09440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GTF71_RS09445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTF71_RS09475	COG0366	Alpha amylase catalytic
GTF71_RS09480	COG1263	PTS System
GTF71_RS09480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTF71_RS09485	COG1609	Transcriptional regulator
GTF71_RS09490	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GTF71_RS09495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GTF71_RS09500	COG2011	ABC-type metal ion transport system permease component
GTF71_RS09505	COG1464	Belongs to the NlpA lipoprotein family
GTF71_RS09510	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GTF71_RS09520	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GTF71_RS09520	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GTF71_RS09530	COG3706	GGDEF domain
GTF71_RS09535	COG1611	Belongs to the LOG family
GTF71_RS09540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GTF71_RS09545	COG2363	Small membrane protein
GTF71_RS09550	COG0583	DNA-binding transcription factor activity
GTF71_RS09555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GTF71_RS09555	COG0301	tRNA thio-modification
GTF71_RS09565	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GTF71_RS09570	COG1722	exodeoxyribonuclease VII activity
GTF71_RS09575	COG0142	geranyltranstransferase activity
GTF71_RS09580	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GTF71_RS09585	COG0564	pseudouridine synthase activity
GTF71_RS09590	COG3098	single-species biofilm formation
GTF71_RS09605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTF71_RS09615	COG1671	Belongs to the UPF0178 family
GTF71_RS09620	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GTF71_RS09625	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GTF71_RS09630	COG0254	rRNA binding
GTF71_RS09635	COG1720	tRNA m6t6A37 methyltransferase activity
GTF71_RS09640	COG0442	prolyl-tRNA aminoacylation
GTF71_RS09665	COG0047	phosphoribosylformylglycinamidine synthase activity
GTF71_RS09665	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GTF71_RS09675	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GTF71_RS09685	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GTF71_RS09715	COG0484	heat shock protein binding
GTF71_RS09720	COG0443	Heat shock 70 kDa protein
GTF71_RS09730	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GTF71_RS09735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GTF71_RS09740	COG0497	DNA recombination
GTF71_RS09745	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTF71_RS09750	COG2914	Belongs to the UPF0125 (RnfH) family
GTF71_RS09755	COG2867	negative regulation of translational initiation
GTF71_RS09760	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GTF71_RS09770	COG0582	viral genome integration into host DNA
GTF71_RS09780	COG0582	viral genome integration into host DNA
GTF71_RS09785	COG3064	Membrane
GTF71_RS09795	COG0739	heme binding
GTF71_RS09810	COG0840	transmembrane signaling receptor activity
GTF71_RS09815	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GTF71_RS09820	COG2207	Transcriptional regulator
GTF71_RS09830	COG1459	type II secretion system
GTF71_RS09835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GTF71_RS09855	COG4796	Type ii and iii secretion system protein
GTF71_RS09870	COG2165	general secretion pathway protein
GTF71_RS09880	COG3710	Transcriptional regulator
GTF71_RS09885	COG0840	transmembrane signaling receptor activity
GTF71_RS09890	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GTF71_RS09910	COG1012	belongs to the aldehyde dehydrogenase family
GTF71_RS09965	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GTF71_RS09970	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GTF71_RS09975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GTF71_RS09995	COG3051	citrate lyase alpha subunit
GTF71_RS10000	COG2301	Belongs to the HpcH HpaI aldolase family
GTF71_RS10010	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GTF71_RS10020	COG3630	sodium ion export across plasma membrane
GTF71_RS10025	COG0511	ligase activity, forming carbon-carbon bonds
GTF71_RS10025	COG5016	pyruvate
GTF71_RS10030	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GTF71_RS10040	COG4565	transcriptional regulatory protein
GTF71_RS10055	COG0583	DNA-binding transcription factor activity
GTF71_RS10065	COG1115	amino acid carrier protein
GTF71_RS10070	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GTF71_RS10075	COG0583	DNA-binding transcription factor activity
GTF71_RS10085	COG1120	ATPase activity
GTF71_RS10090	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTF71_RS10095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTF71_RS10100	COG4592	Periplasmic binding protein
GTF71_RS10110	COG1028	Short-chain dehydrogenase reductase Sdr
GTF71_RS10115	COG1169	isochorismate synthase
GTF71_RS10120	COG1021	2,3-dihydroxybenzoate-AMP ligase
GTF71_RS10125	COG3433	isochorismatase activity
GTF71_RS10125	COG1535	isochorismatase
GTF71_RS10130	COG1584	GPR1 FUN34 yaaH family protein
GTF71_RS10140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GTF71_RS10140	COG0519	Catalyzes the synthesis of GMP from XMP
GTF71_RS10145	COG0516	GMP reductase activity
GTF71_RS10145	COG0517	IMP dehydrogenase activity
GTF71_RS10150	COG1570	exodeoxyribonuclease VII activity
GTF71_RS10165	COG1160	GTP binding
GTF71_RS10170	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTF71_RS10175	COG2976	Protein conserved in bacteria
GTF71_RS10180	COG0124	histidyl-tRNA synthetase
GTF71_RS10185	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GTF71_RS10195	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GTF71_RS10200	COG0105	UTP biosynthetic process
GTF71_RS10205	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GTF71_RS10210	COG2975	iron-sulfur cluster assembly
GTF71_RS10215	COG0633	Ferredoxin
GTF71_RS10220	COG0443	Heat shock 70 kDa protein
GTF71_RS10225	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GTF71_RS10235	COG0822	iron-sulfur transferase activity
GTF71_RS10240	COG1104	cysteine desulfurase activity
GTF71_RS10245	COG1959	2 iron, 2 sulfur cluster binding
GTF71_RS10255	COG0483	inositol monophosphate 1-phosphatase activity
GTF71_RS10260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GTF71_RS10265	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GTF71_RS10270	COG1862	Preprotein translocase
GTF71_RS10285	COG0517	IMP dehydrogenase activity
GTF71_RS10295	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GTF71_RS10300	COG0583	DNA-binding transcription factor activity
GTF71_RS10305	COG0450	alkyl hydroperoxide reductase
GTF71_RS10310	COG3142	Participates in the control of copper homeostasis
GTF71_RS10325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GTF71_RS10330	COG0581	inorganic phosphate transmembrane transporter activity
GTF71_RS10340	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GTF71_RS10345	COG0248	Ppx GppA phosphatase
GTF71_RS10355	COG5002	protein histidine kinase activity
GTF71_RS10360	COG0745	RESPONSE REGULATOR receiver
GTF71_RS10375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GTF71_RS10415	COG0542	response to heat
GTF71_RS10425	COG0564	pseudouridine synthase activity
GTF71_RS10430	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GTF71_RS10435	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GTF71_RS10440	COG0077	Prephenate dehydratase
GTF71_RS10440	COG1605	Chorismate mutase
GTF71_RS10445	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GTF71_RS10450	COG5001	Diguanylate cyclase
GTF71_RS10460	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GTF71_RS10470	COG0488	(ABC) transporter
GTF71_RS10480	COG1605	Chorismate mutase
GTF71_RS10480	COG0287	Prephenate dehydrogenase
GTF71_RS10485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GTF71_RS10490	COG3275	phosphorelay sensor kinase activity
GTF71_RS10495	COG3279	Response regulator of the LytR AlgR family
GTF71_RS10505	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GTF71_RS10510	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GTF71_RS10525	COG1966	Carbon starvation protein
GTF71_RS10530	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GTF71_RS10535	COG1047	Peptidyl-prolyl cis-trans
GTF71_RS10550	COG0196	riboflavin kinase activity
GTF71_RS10555	COG0728	peptidoglycan biosynthetic process
GTF71_RS10560	COG0268	Binds directly to 16S ribosomal RNA
GTF71_RS10565	COG0640	Transcriptional regulator
GTF71_RS10570	COG0583	DNA-binding transcription factor activity
GTF71_RS10575	COG1283	sodium-dependent phosphate transmembrane transporter activity
GTF71_RS10585	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GTF71_RS10590	COG0730	response to heat
GTF71_RS10595	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GTF71_RS10600	COG0494	nUDIX hydrolase
GTF71_RS10610	COG0667	Aldo Keto reductase
GTF71_RS10620	COG2204	response regulator
GTF71_RS10625	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GTF71_RS10645	COG0513	Belongs to the DEAD box helicase family
GTF71_RS10670	COG3153	acetyltransferase
GTF71_RS10675	COG3154	lipid carrier protein
GTF71_RS10685	COG0826	peptidase U32
GTF71_RS10690	COG0826	peptidase U32
GTF71_RS10715	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GTF71_RS10725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GTF71_RS10730	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GTF71_RS10735	COG0195	Participates in both transcription termination and antitermination
GTF71_RS10740	COG0779	Required for maturation of 30S ribosomal subunits
GTF71_RS10755	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GTF71_RS10765	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GTF71_RS10770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GTF71_RS10775	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GTF71_RS10780	COG1534	Rna-binding protein
GTF71_RS10785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GTF71_RS10790	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTF71_RS10795	COG2027	D-alanyl-D-alanine carboxypeptidase
GTF71_RS10800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GTF71_RS10805	COG0739	heme binding
GTF71_RS10820	COG0316	Belongs to the HesB IscA family
GTF71_RS10825	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GTF71_RS10830	COG0628	permease
GTF71_RS10835	COG2813	Specifically methylates the guanine in position
GTF71_RS10840	COG0784	Response regulator, receiver
GTF71_RS10840	COG2205	protein histidine kinase activity
GTF71_RS10845	COG0747	negative chemotaxis
GTF71_RS10850	COG0601	transmembrane transport
GTF71_RS10855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTF71_RS10860	COG0444	Belongs to the ABC transporter superfamily
GTF71_RS10865	COG4608	Belongs to the ABC transporter superfamily
GTF71_RS10875	COG2971	BadF BadG BcrA BcrD
GTF71_RS10895	COG3842	ATPase activity
GTF71_RS10905	COG1840	ABC-type Fe3 transport system, periplasmic component
GTF71_RS10910	COG0004	ammonium transporteR
GTF71_RS10915	COG0347	Belongs to the P(II) protein family
GTF71_RS10920	COG3112	Uncharacterised protein family (UPF0231)
GTF71_RS10925	COG1049	propionate catabolic process, 2-methylcitrate cycle
GTF71_RS10930	COG1752	Esterase of the alpha-beta hydrolase superfamily
GTF71_RS10935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GTF71_RS10940	COG1643	Atp-dependent helicase
GTF71_RS10950	COG1489	DNA binding
GTF71_RS10960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GTF71_RS10970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GTF71_RS10975	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GTF71_RS10980	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GTF71_RS10985	COG0842	Transport permease protein
GTF71_RS10990	COG1131	(ABC) transporter
GTF71_RS10995	COG0659	secondary active sulfate transmembrane transporter activity
GTF71_RS11000	COG0288	reversible hydration of carbon dioxide
GTF71_RS11015	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GTF71_RS11020	COG3107	peptidoglycan biosynthetic process
GTF71_RS11025	COG0792	nuclease activity
GTF71_RS11030	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GTF71_RS11035	COG2823	Periplasmic or secreted lipoprotein
GTF71_RS11040	COG2969	positive regulation of protein catabolic process
GTF71_RS11045	COG0625	glutathione transferase activity
GTF71_RS11050	COG2857	Cytochrome c1
GTF71_RS11055	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GTF71_RS11060	COG0723	plastoquinol--plastocyanin reductase activity
GTF71_RS11065	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GTF71_RS11070	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GTF71_RS11075	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GTF71_RS11085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GTF71_RS11090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GTF71_RS11095	COG0335	large ribosomal subunit rRNA binding
GTF71_RS11100	COG0336	Belongs to the RNA methyltransferase TrmD family
GTF71_RS11105	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GTF71_RS11110	COG0228	four-way junction DNA binding
GTF71_RS11115	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GTF71_RS11120	COG4137	Cytochrome C assembly protein
GTF71_RS11125	COG4536	flavin adenine dinucleotide binding
GTF71_RS11130	COG1854	S-ribosylhomocysteine lyase activity
GTF71_RS11135	COG2918	glutathione biosynthetic process
GTF71_RS11140	COG0612	Peptidase, M16
GTF71_RS11145	COG1238	metal cluster binding
GTF71_RS11155	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GTF71_RS11160	COG0511	ligase activity, forming carbon-carbon bonds
GTF71_RS11160	COG5016	pyruvate
GTF71_RS11165	COG3630	sodium ion export across plasma membrane
GTF71_RS11210	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GTF71_RS11215	COG0527	aspartate kinase activity
GTF71_RS11220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GTF71_RS11230	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GTF71_RS11240	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GTF71_RS11245	COG4208	sulfate ABC transporter
GTF71_RS11265	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GTF71_RS11270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GTF71_RS11280	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GTF71_RS11285	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GTF71_RS11290	COG0585	pseudouridine synthase activity
GTF71_RS11295	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GTF71_RS11300	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GTF71_RS11305	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GTF71_RS11310	COG1968	undecaprenyl-diphosphatase activity
GTF71_RS11315	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GTF71_RS11320	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GTF71_RS11325	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GTF71_RS11335	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GTF71_RS11340	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GTF71_RS11345	COG1610	YqeY-like protein
GTF71_RS11350	COG0358	DNA primase activity
GTF71_RS11365	COG0582	viral genome integration into host DNA
GTF71_RS11370	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GTF71_RS11375	COG0840	transmembrane signaling receptor activity
GTF71_RS11380	COG2207	Transcriptional regulator
GTF71_RS11385	COG0840	transmembrane signaling receptor activity
GTF71_RS11395	COG2003	Belongs to the UPF0758 family
GTF71_RS11425	COG0739	heme binding
GTF71_RS11435	COG4969	Belongs to the N-Me-Phe pilin family
GTF71_RS11450	COG0328	RNA-DNA hybrid ribonuclease activity
GTF71_RS11500	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GTF71_RS11505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GTF71_RS11510	COG1349	DNA-binding transcription factor activity
GTF71_RS11530	COG1279	arginine transmembrane transporter activity
GTF71_RS11535	COG0668	transmembrane transport
GTF71_RS11540	COG0191	fructose-bisphosphate aldolase activity
GTF71_RS11545	COG0126	phosphoglycerate kinase activity
GTF71_RS11550	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GTF71_RS11555	COG4771	TonB-dependent receptor
GTF71_RS11560	COG0583	DNA-binding transcription factor activity
GTF71_RS11565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GTF71_RS11570	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GTF71_RS11580	COG2356	endonuclease I
GTF71_RS11585	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GTF71_RS11590	COG0189	ligase activity
GTF71_RS11595	COG1678	Uncharacterized ACR, COG1678
GTF71_RS11600	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GTF71_RS11605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GTF71_RS11625	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GTF71_RS11630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GTF71_RS11635	COG0762	integral membrane protein
GTF71_RS11640	COG1872	DUF167
GTF71_RS11650	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GTF71_RS11655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GTF71_RS11660	COG2066	Belongs to the glutaminase family
GTF71_RS11670	COG1194	a g-specific adenine glycosylase
GTF71_RS11675	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GTF71_RS11680	COG0741	lytic transglycosylase activity
GTF71_RS11735	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GTF71_RS11740	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GTF71_RS11745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTF71_RS11750	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GTF71_RS11755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GTF71_RS11760	COG2967	ApaG domain
GTF71_RS11765	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GTF71_RS11775	COG3610	response to peptide
GTF71_RS11780	COG2966	Psort location CytoplasmicMembrane, score
GTF71_RS11785	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GTF71_RS11790	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GTF71_RS11795	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GTF71_RS11800	COG0142	geranyltranstransferase activity
GTF71_RS11805	COG0531	amino acid
GTF71_RS11810	COG0039	L-malate dehydrogenase activity
GTF71_RS11815	COG1438	arginine binding
GTF71_RS11820	COG2358	TRAP transporter, solute receptor (TAXI family
GTF71_RS11830	COG0589	response to stress
GTF71_RS11850	COG2235	arginine
GTF71_RS11855	COG0312	modulator of DNA gyrase
GTF71_RS11860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GTF71_RS11865	COG3164	Protein of unknown function
GTF71_RS11870	COG1530	ribonuclease E activity
GTF71_RS11875	COG0424	maF-like protein
GTF71_RS11880	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GTF71_RS11885	COG1792	Involved in formation and maintenance of cell shape
GTF71_RS11890	COG1077	Cell shape determining protein MreB Mrl
GTF71_RS11935	COG1459	type II secretion system
GTF71_RS11940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GTF71_RS11950	COG3409	Peptidoglycan-binding domain 1 protein
GTF71_RS11950	COG3267	Type II secretory pathway component ExeA
GTF71_RS11975	COG2199	diguanylate cyclase activity
GTF71_RS11975	COG2200	EAL domain
GTF71_RS11980	COG0629	single-stranded DNA binding
GTF71_RS11995	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GTF71_RS12005	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GTF71_RS12010	COG0527	aspartate kinase activity
GTF71_RS12015	COG1410	methionine synthase
GTF71_RS12015	COG0646	methionine synthase
GTF71_RS12085	COG0175	sulfate reduction
GTF71_RS12095	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GTF71_RS12120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GTF71_RS12125	COG0735	belongs to the Fur family
GTF71_RS12145	COG0432	Pfam Uncharacterised protein family UPF0047
GTF71_RS12150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GTF71_RS12165	COG0359	binds to the 23S rRNA
GTF71_RS12170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GTF71_RS12175	COG2965	DNA replication, synthesis of RNA primer
GTF71_RS12180	COG0360	Binds together with S18 to 16S ribosomal RNA
GTF71_RS12190	COG2906	2 iron, 2 sulfur cluster binding
GTF71_RS12195	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GTF71_RS12200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GTF71_RS12205	COG0049	tRNA binding
GTF71_RS12210	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GTF71_RS12220	COG2923	Belongs to the DsrF TusC family
GTF71_RS12225	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GTF71_RS12230	COG2964	Protein conserved in bacteria
GTF71_RS12235	COG0545	Peptidyl-prolyl cis-trans isomerase
GTF71_RS12245	COG2900	Belongs to the SlyX family
GTF71_RS12250	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GTF71_RS12255	COG0330	HflC and HflK could
GTF71_RS12260	COG0330	HflC and HflK could
GTF71_RS12265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GTF71_RS12270	COG1923	regulation of RNA biosynthetic process
GTF71_RS12275	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GTF71_RS12280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GTF71_RS12290	COG0802	atpase or kinase
GTF71_RS12295	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GTF71_RS12340	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GTF71_RS12345	COG1162	GTPase activity
GTF71_RS12350	COG0688	phosphatidylethanolamine metabolic process
GTF71_RS12355	COG0471	metal ion transport
GTF71_RS12365	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GTF71_RS12370	COG4942	peptidase
GTF71_RS12385	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GTF71_RS12390	COG2816	NAD+ diphosphatase activity
GTF71_RS12395	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GTF71_RS12400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GTF71_RS12405	COG0085	RNA polymerase activity
GTF71_RS12410	COG0222	ribosome binding
GTF71_RS12415	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GTF71_RS12425	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GTF71_RS12430	COG0250	Participates in transcription elongation, termination and antitermination
GTF71_RS12435	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GTF71_RS12440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GTF71_RS12465	COG1072	(Pantothenic acid kinase))
GTF71_RS12475	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GTF71_RS12485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GTF71_RS12530	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GTF71_RS12545	COG3118	belongs to the thioredoxin family
GTF71_RS12550	COG0513	Belongs to the DEAD box helicase family
GTF71_RS12555	COG0248	Ppx GppA phosphatase
GTF71_RS12560	COG0784	Response regulator, receiver
GTF71_RS12560	COG2205	protein histidine kinase activity
GTF71_RS12565	COG2814	Major facilitator Superfamily
GTF71_RS12580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GTF71_RS12585	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GTF71_RS12590	COG0511	ligase activity, forming carbon-carbon bonds
GTF71_RS12595	COG0439	Biotin carboxylase
GTF71_RS12600	COG2264	protein methyltransferase activity
GTF71_RS12605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GTF71_RS12610	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GTF71_RS12615	COG1609	Transcriptional regulator
GTF71_RS12620	COG0129	dihydroxy-acid dehydratase activity
GTF71_RS12625	COG3265	gluconokinase activity
GTF71_RS12635	COG0800	Aldolase
GTF71_RS12655	COG0840	transmembrane signaling receptor activity
GTF71_RS12660	COG1982	Orn Lys Arg decarboxylase major
GTF71_RS12665	COG0531	amino acid
GTF71_RS12670	COG3710	Transcriptional regulator
GTF71_RS12675	COG0789	Transcriptional regulator
GTF71_RS12690	COG0151	Belongs to the GarS family
GTF71_RS12700	COG0776	regulation of translation
GTF71_RS12705	COG1253	flavin adenine dinucleotide binding
GTF71_RS12710	COG1940	carbohydrate kinase activity
GTF71_RS12720	COG3068	Protein conserved in bacteria
GTF71_RS12730	COG1573	uracil-dna glycosylase
GTF71_RS12735	COG0668	transmembrane transport
GTF71_RS12740	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GTF71_RS12745	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GTF71_RS12790	COG1454	alcohol dehydrogenase
GTF71_RS12790	COG1012	belongs to the aldehyde dehydrogenase family
GTF71_RS12795	COG0318	PFAM AMP-dependent synthetase and ligase
GTF71_RS12825	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GTF71_RS12830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GTF71_RS12835	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GTF71_RS12835	COG0662	Cupin 2, conserved barrel domain protein
GTF71_RS12840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GTF71_RS12875	COG1519	Transferase
GTF71_RS12905	COG3642	lipopolysaccharide core region biosynthetic process
GTF71_RS12910	COG0859	PFAM glycosyl transferase family 9
GTF71_RS12915	COG0463	Glycosyl transferase, family 2
GTF71_RS12920	COG0859	PFAM glycosyl transferase family 9
GTF71_RS12925	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GTF71_RS12930	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GTF71_RS12940	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GTF71_RS12945	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GTF71_RS12950	COG2003	Belongs to the UPF0758 family
GTF71_RS12960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GTF71_RS12970	COG1309	transcriptional regulator
GTF71_RS12975	COG1560	Kdo2-lipid A biosynthetic process
GTF71_RS12980	COG1560	Kdo2-lipid A biosynthetic process
GTF71_RS12985	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GTF71_RS12990	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GTF71_RS12995	COG1561	YicC-like family, N-terminal region
GTF71_RS13000	COG2862	Uncharacterized protein family, UPF0114
GTF71_RS13005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTF71_RS13005	COG1263	PTS System
GTF71_RS13010	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GTF71_RS13030	COG1120	ATPase activity
GTF71_RS13035	COG4774	siderophore transport
GTF71_RS13040	COG1132	(ABC) transporter
GTF71_RS13055	COG0514	ATP-dependent DNA helicase (RecQ)
GTF71_RS13060	COG2962	Rard protein
GTF71_RS13075	COG1280	lysine exporter protein (LysE YggA)
GTF71_RS13080	COG0210	DNA helicase
GTF71_RS13090	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GTF71_RS13095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GTF71_RS13135	COG3621	Patatin-like phospholipase
GTF71_RS13160	COG2131	deaminase
GTF71_RS13170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTF71_RS13180	COG0747	negative chemotaxis
GTF71_RS13230	COG1309	transcriptional regulator
GTF71_RS13235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GTF71_RS13240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GTF71_RS13245	COG2960	long-chain fatty acid transporting porin activity
GTF71_RS13250	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GTF71_RS13255	COG0583	DNA-binding transcription factor activity
GTF71_RS13300	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GTF71_RS13305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GTF71_RS13310	COG1739	Uncharacterized protein family UPF0029
GTF71_RS13320	COG0183	Belongs to the thiolase family
GTF71_RS13325	COG0583	DNA-binding transcription factor activity
GTF71_RS13330	COG2814	Major facilitator Superfamily
GTF71_RS13335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GTF71_RS13340	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GTF71_RS13345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GTF71_RS13350	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GTF71_RS13355	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GTF71_RS13360	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GTF71_RS13365	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GTF71_RS13375	COG0356	it plays a direct role in the translocation of protons across the membrane
GTF71_RS13380	COG3312	ion transport
GTF71_RS13385	COG1475	DNA binding
GTF71_RS13390	COG1192	Involved in chromosome partitioning
GTF71_RS13400	COG0445	tRNA wobble uridine modification
GTF71_RS13405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GTF71_RS13410	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GTF71_RS13415	COG0706	membrane insertase activity
GTF71_RS13425	COG0594	ribonuclease P activity
GTF71_RS13430	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GTF71_RS13435	COG1126	abc transporter atp-binding protein
GTF71_RS13480	COG0217	transcriptional regulatory protein
GTF71_RS13485	COG2084	Dehydrogenase
GTF71_RS13500	COG2909	trisaccharide binding
GTF71_RS13505	COG0058	SHG alpha-glucan phosphorylase activity
GTF71_RS13510	COG1640	4-alpha-glucanotransferase
GTF71_RS13515	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GTF71_RS13525	COG3501	Rhs element vgr protein
GTF71_RS13560	COG0471	metal ion transport
GTF71_RS13565	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GTF71_RS13605	COG0671	phosphoesterase, PA-phosphatase related
GTF71_RS13610	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GTF71_RS13620	COG1999	signal sequence binding
GTF71_RS13635	COG0786	glutamate:sodium symporter activity
GTF71_RS13655	COG1566	PFAM secretion protein HlyD family protein
GTF71_RS13665	COG3706	GGDEF domain
GTF71_RS13680	COG0813	purine-nucleoside phosphorylase activity
GTF71_RS13685	COG3272	Protein of unknown function (DUF1722)
GTF71_RS13695	COG0415	Belongs to the DNA photolyase family
GTF71_RS13700	COG1388	LysM domain
GTF71_RS13700	COG1376	ErfK ybiS ycfS ynhG family protein
GTF71_RS13710	COG0513	Belongs to the DEAD box helicase family
GTF71_RS13715	COG1770	oligopeptidase
GTF71_RS13745	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GTF71_RS13750	COG0573	inorganic phosphate transmembrane transporter activity
GTF71_RS13755	COG0581	inorganic phosphate transmembrane transporter activity
GTF71_RS13760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GTF71_RS13780	COG0659	secondary active sulfate transmembrane transporter activity
GTF71_RS13790	COG0739	heme binding
GTF71_RS13795	COG3300	MHYT domain
GTF71_RS13795	COG5001	Diguanylate cyclase
GTF71_RS13800	COG0583	DNA-binding transcription factor activity
GTF71_RS13805	COG2814	Major facilitator Superfamily
GTF71_RS13825	COG1301	dicarboxylic acid transport
GTF71_RS13835	COG1342	Belongs to the UPF0251 family
GTF71_RS13865	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GTF71_RS13870	COG0673	inositol 2-dehydrogenase activity
GTF71_RS13880	COG2771	luxR family
GTF71_RS13880	COG2200	EAL domain
GTF71_RS13885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTF71_RS13895	COG0564	pseudouridine synthase activity
GTF71_RS13985	COG3501	Rhs element vgr protein
GTF71_RS14000	COG1869	D-ribose catabolic process
GTF71_RS14005	COG1129	ABC transporter
GTF71_RS14010	COG1172	Belongs to the binding-protein-dependent transport system permease family
GTF71_RS14015	COG1879	ABC-type sugar transport system periplasmic component
GTF71_RS14020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTF71_RS14025	COG1609	Transcriptional regulator
GTF71_RS14035	COG3201	nicotinamide mononucleotide transporter
GTF71_RS14040	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GTF71_RS14050	COG0584	glycerophosphoryl diester phosphodiesterase
GTF71_RS14055	COG2271	Major facilitator Superfamily
GTF71_RS14090	COG0579	oxidoreductase
GTF71_RS14100	COG0242	peptide deformylase activity
GTF71_RS14110	COG1320	monovalent cation:proton antiporter activity
GTF71_RS14115	COG2212	antiporter activity
GTF71_RS14135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GTF71_RS14135	COG2111	Na H antiporter
GTF71_RS14145	COG0589	response to stress
GTF71_RS14150	COG0814	amino acid
GTF71_RS14165	COG3530	Putative quorum-sensing-regulated virulence factor
GTF71_RS14175	COG5002	protein histidine kinase activity
GTF71_RS14175	COG5001	Diguanylate cyclase
GTF71_RS14180	COG1278	Cold shock
GTF71_RS14195	COG2304	oxidoreductase activity
GTF71_RS14215	COG0714	Associated with various cellular activities
GTF71_RS14220	COG0840	transmembrane signaling receptor activity
GTF71_RS14235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GTF71_RS14240	COG2195	Cleaves the N-terminal amino acid of tripeptides
GTF71_RS14250	COG3604	Transcriptional regulator
GTF71_RS14255	COG1017	nitric oxide dioxygenase activity
GTF71_RS14255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GTF71_RS14260	COG1278	Cold shock
GTF71_RS14265	COG3036	rescue of stalled ribosome
GTF71_RS14290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GTF71_RS14290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GTF71_RS14295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GTF71_RS14305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GTF71_RS14315	COG0516	GMP reductase activity
GTF71_RS14350	COG0513	Belongs to the DEAD box helicase family
GTF71_RS14355	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GTF71_RS14360	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GTF71_RS14365	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GTF71_RS14370	COG3437	response regulator, receiver
GTF71_RS14370	COG0784	Response regulator, receiver
GTF71_RS14375	COG4191	Histidine kinase
GTF71_RS14375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTF71_RS14385	COG1757	Na H antiporter
GTF71_RS14390	COG2814	Major facilitator Superfamily
GTF71_RS14400	COG3706	GGDEF domain
GTF71_RS14405	COG3240	lipase activity
GTF71_RS14415	COG0840	transmembrane signaling receptor activity
GTF71_RS14420	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GTF71_RS14425	COG5380	lipid catabolic process
GTF71_RS14450	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTF71_RS14455	COG4605	iron ion homeostasis
GTF71_RS14460	COG4604	ABC transporter, ATP-binding protein
GTF71_RS14465	COG2207	Transcriptional regulator
GTF71_RS14480	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GTF71_RS14500	COG0745	RESPONSE REGULATOR receiver
GTF71_RS14510	COG3623	hexulose-6-phosphate isomerase
GTF71_RS14515	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
GTF71_RS14520	COG0561	phosphatase activity
GTF71_RS14550	COG3038	cytochrome b561
GTF71_RS14555	COG0366	Alpha amylase catalytic
GTF71_RS14580	COG0745	RESPONSE REGULATOR receiver
GTF71_RS14585	COG5002	protein histidine kinase activity
GTF71_RS14610	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GTF71_RS14625	COG2814	Major facilitator Superfamily
GTF71_RS14640	COG1686	Belongs to the peptidase S11 family
GTF71_RS14665	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GTF71_RS14665	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GTF71_RS14670	COG0509	glycine decarboxylation via glycine cleavage system
GTF71_RS14675	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GTF71_RS14685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GTF71_RS14695	COG3039	Transposase
GTF71_RS14730	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GTF71_RS14735	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GTF71_RS14800	COG1028	Short-chain dehydrogenase reductase Sdr
GTF71_RS14835	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GTF71_RS14865	COG0494	nUDIX hydrolase
GTF71_RS14885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTF71_RS14890	COG3040	lipid binding
GTF71_RS14920	COG3041	Addiction module toxin RelE StbE family
GTF71_RS15015	COG1619	proteins homologs of microcin C7 resistance protein MccF
GTF71_RS15070	COG0346	lactoylglutathione lyase activity
GTF71_RS15090	COG3040	lipid binding
GTF71_RS15105	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GTF71_RS15115	COG1280	lysine exporter protein (LysE YggA)
GTF71_RS15300	COG3549	Plasmid maintenance system killer
GTF71_RS15305	COG3093	addiction module antidote protein HigA
GTF71_RS15325	COG0384	phenazine biosynthesis protein PhzF
GTF71_RS15355	COG0346	lactoylglutathione lyase activity
GTF71_RS15375	COG3040	lipid binding
GTF71_RS15430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTF71_RS15530	COG1619	proteins homologs of microcin C7 resistance protein MccF
GTF71_RS15555	COG3040	lipid binding
GTF71_RS15610	COG4977	sequence-specific DNA binding
GTF71_RS15700	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
GTF71_RS15705	COG2944	sequence-specific DNA binding
GTF71_RS15720	COG3039	Transposase
GTF71_RS15745	COG0346	lactoylglutathione lyase activity
GTF71_RS15895	COG0346	lactoylglutathione lyase activity
GTF71_RS15915	COG1328	CTP reductase activity
GTF71_RS15920	COG0602	queuosine metabolic process
GTF71_RS15930	COG0189	ligase activity
GTF71_RS15930	COG4067	protein conserved in archaea
GTF71_RS15935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTF71_RS15935	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GTF71_RS15935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GTF71_RS15940	COG1105	Belongs to the carbohydrate kinase PfkB family
GTF71_RS15945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTF71_RS15945	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTF71_RS15950	COG1609	Transcriptional regulator
GTF71_RS15955	COG0420	3'-5' exonuclease activity
GTF71_RS15960	COG0419	ATPase involved in DNA repair
GTF71_RS15965	COG2205	protein histidine kinase activity
GTF71_RS15965	COG0784	Response regulator, receiver
GTF71_RS15970	COG0156	8-amino-7-oxononanoate synthase activity
GTF71_RS15985	COG0523	cobalamin synthesis protein
GTF71_RS16000	COG1013	pyruvate-flavodoxin oxidoreductase activity
GTF71_RS16000	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GTF71_RS16000	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GTF71_RS16000	COG0674	pyruvate-flavodoxin oxidoreductase activity
GTF71_RS16005	COG2205	protein histidine kinase activity
GTF71_RS16010	COG0745	RESPONSE REGULATOR receiver
GTF71_RS16015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GTF71_RS16020	COG0586	Pfam SNARE associated Golgi protein
GTF71_RS16030	COG2200	EAL domain
GTF71_RS16040	COG3038	cytochrome b561
GTF71_RS16050	COG2116	formate transmembrane transporter activity
GTF71_RS16055	COG0583	DNA-binding transcription factor activity
GTF71_RS16065	COG3593	DNA synthesis involved in DNA repair
GTF71_RS16070	COG0737	Belongs to the 5'-nucleotidase family
GTF71_RS16085	COG2824	Alkylphosphonate utilization operon protein PhnA
GTF71_RS16135	COG3706	GGDEF domain
GTF71_RS16150	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GTF71_RS16155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GTF71_RS16165	COG0745	RESPONSE REGULATOR receiver
GTF71_RS16180	COG3140	Belongs to the UPF0181 family
GTF71_RS16185	COG0023	Translation Initiation Factor
GTF71_RS16205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTF71_RS16205	COG1042	CoA-binding domain protein
GTF71_RS16205	COG0045	succinate-CoA ligase (ADP-forming) activity
GTF71_RS16210	COG0583	DNA-binding transcription factor activity
GTF71_RS16215	COG1629	transport
GTF71_RS16215	COG4771	TonB-dependent receptor
GTF71_RS16230	COG2050	protein possibly involved in aromatic compounds catabolism
GTF71_RS16250	COG0625	glutathione transferase activity
GTF71_RS16265	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GTF71_RS16270	COG4172	Belongs to the ABC transporter superfamily
GTF71_RS16275	COG4239	(ABC) transporter, permease
GTF71_RS16280	COG4174	ABC transporter (Permease)
GTF71_RS16285	COG4166	transmembrane transport
GTF71_RS16310	COG3104	oligopeptide transport
GTF71_RS16330	COG3842	ATPase activity
GTF71_RS16340	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GTF71_RS16350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTF71_RS16355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GTF71_RS16360	COG1011	Hydrolase
GTF71_RS16370	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GTF71_RS16375	COG1970	mechanosensitive ion channel activity
GTF71_RS16380	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GTF71_RS16385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GTF71_RS16385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GTF71_RS16390	COG0302	gtp cyclohydrolase
GTF71_RS16400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GTF71_RS16410	COG2897	thiosulfate sulfurtransferase activity
GTF71_RS16415	COG2390	Transcriptional regulator
GTF71_RS16425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GTF71_RS16450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GTF71_RS16475	COG0583	DNA-binding transcription factor activity
GTF71_RS16480	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GTF71_RS16520	COG0446	pyridine nucleotide-disulphide oxidoreductase
GTF71_RS16565	COG1263	PTS System
GTF71_RS16565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GTF71_RS16575	COG1621	beta-fructofuranosidase activity
GTF71_RS16580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTF71_RS16585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GTF71_RS16595	COG2885	chlorophyll binding
GTF71_RS16600	COG0545	Peptidyl-prolyl cis-trans isomerase
GTF71_RS16605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GTF71_RS16610	COG0840	transmembrane signaling receptor activity
GTF71_RS16615	COG3069	C4-dicarboxylate transmembrane transporter activity
GTF71_RS16620	COG1760	l-serine dehydratase
GTF71_RS16640	COG1609	Transcriptional regulator
GTF71_RS16645	COG2197	response regulator
GTF71_RS16650	COG3850	Histidine kinase
GTF71_RS16655	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GTF71_RS16665	COG0243	molybdopterin cofactor binding
GTF71_RS16685	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GTF71_RS16690	COG2197	response regulator
GTF71_RS16695	COG3851	Histidine kinase
GTF71_RS16700	COG2271	Major facilitator Superfamily
GTF71_RS16705	COG1840	ABC-type Fe3 transport system, periplasmic component
GTF71_RS16715	COG3842	ATPase activity
GTF71_RS16720	COG3243	poly(R)-hydroxyalkanoic acid synthase
GTF71_RS16730	COG0183	Belongs to the thiolase family
GTF71_RS16740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GTF71_RS16745	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GTF71_RS16760	COG3706	GGDEF domain
GTF71_RS16765	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GTF71_RS16775	COG1979	alcohol dehydrogenase
GTF71_RS16790	COG4191	Histidine kinase
GTF71_RS16800	COG2271	Major facilitator Superfamily
GTF71_RS16805	COG0469	pyruvate kinase activity
GTF71_RS16810	COG0784	Response regulator, receiver
GTF71_RS16810	COG2205	protein histidine kinase activity
GTF71_RS16810	COG2198	Histidine kinase
GTF71_RS16815	COG1879	ABC-type sugar transport system periplasmic component
GTF71_RS16820	COG1803	Methylglyoxal synthase
GTF71_RS16825	COG1335	isochorismatase
GTF71_RS16830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GTF71_RS16845	COG0210	DNA helicase
GTF71_RS16850	COG1289	transmembrane transporter activity
GTF71_RS16880	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GTF71_RS16885	COG4149	molybdate abc transporter
GTF71_RS16890	COG0725	ABC transporter, periplasmic molybdate-binding protein
GTF71_RS16895	COG1492	cobalamin metabolic process
GTF71_RS16935	COG0784	Response regulator, receiver
GTF71_RS16935	COG5002	protein histidine kinase activity
GTF71_RS16940	COG1879	ABC-type sugar transport system periplasmic component
GTF71_RS16950	COG2827	Endonuclease containing a URI domain
GTF71_RS16965	COG2926	Belongs to the UPF0265 family
GTF71_RS16975	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GTF71_RS16980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GTF71_RS16985	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GTF71_RS16990	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GTF71_RS16995	COG0247	lactate metabolic process
GTF71_RS17000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GTF71_RS17005	COG3118	belongs to the thioredoxin family
GTF71_RS17035	COG0583	DNA-binding transcription factor activity
GTF71_RS17040	COG4160	amino acid transport
GTF71_RS17045	COG4215	(ABC) transporter
GTF71_RS17050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTF71_RS17055	COG1126	abc transporter atp-binding protein
GTF71_RS17065	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GTF71_RS17075	COG0494	nUDIX hydrolase
GTF71_RS17080	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GTF71_RS17090	COG1309	transcriptional regulator
GTF71_RS17095	COG0513	Belongs to the DEAD box helicase family
GTF71_RS17100	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GTF71_RS17105	COG0814	amino acid
GTF71_RS17110	COG0840	transmembrane signaling receptor activity
GTF71_RS17115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GTF71_RS17120	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GTF71_RS17130	COG1984	allophanate hydrolase subunit 2
GTF71_RS17145	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GTF71_RS17150	COG4181	ATPase activity
GTF71_RS17160	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GTF71_RS17165	COG5001	Diguanylate cyclase
GTF71_RS17165	COG1716	ATPase activity
GTF71_RS17175	COG0484	heat shock protein binding
GTF71_RS17215	COG0546	phosphoglycolate phosphatase activity
GTF71_RS17230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GTF71_RS17235	COG1368	sulfuric ester hydrolase activity
GTF71_RS17245	COG0513	Belongs to the DEAD box helicase family
GTF71_RS17260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GTF71_RS17270	COG3046	protein related to deoxyribodipyrimidine photolyase
GTF71_RS17275	COG3397	chitin binding
GTF71_RS17280	COG3227	Zinc metalloprotease (Elastase)
GTF71_RS17290	COG0010	Belongs to the arginase family
GTF71_RS17295	COG1166	arginine decarboxylase activity
GTF71_RS17305	COG2239	Acts as a magnesium transporter
GTF71_RS17310	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GTF71_RS17315	COG0459	protein refolding
GTF71_RS17325	COG0527	aspartate kinase activity
GTF71_RS17330	COG0662	Cupin 2, conserved barrel domain protein
GTF71_RS17335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GTF71_RS17340	COG0456	acetyltransferase
GTF71_RS17350	COG3186	Phenylalanine-4-hydroxylase
GTF71_RS17355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GTF71_RS17370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GTF71_RS17395	COG1253	flavin adenine dinucleotide binding
GTF71_RS17400	COG1765	OsmC-like protein
GTF71_RS17425	COG0531	amino acid
GTF71_RS17430	COG3706	GGDEF domain
GTF71_RS17440	COG3279	Response regulator of the LytR AlgR family
GTF71_RS17445	COG3275	phosphorelay sensor kinase activity
GTF71_RS17460	COG1136	(ABC) transporter
GTF71_RS17460	COG0577	efflux transmembrane transporter activity
GTF71_RS17465	COG1136	(ABC) transporter
GTF71_RS17475	COG4989	oxidoreductase activity
GTF71_RS17480	COG0366	Alpha amylase catalytic
GTF71_RS17490	COG2067	long-chain fatty acid transport protein
GTF71_RS17495	COG2267	carboxylic ester hydrolase activity
GTF71_RS17505	COG3227	Zinc metalloprotease (Elastase)
GTF71_RS17515	COG3047	cAMP biosynthetic process
GTF71_RS17525	COG1686	Belongs to the peptidase S11 family
GTF71_RS17530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GTF71_RS17535	COG1271	oxidase subunit
GTF71_RS17540	COG1294	oxidase, subunit
GTF71_RS17555	COG3048	D-serine ammonia-lyase activity
GTF71_RS17560	COG0583	DNA-binding transcription factor activity
GTF71_RS17605	COG1063	alcohol dehydrogenase
GTF71_RS17630	COG0346	lactoylglutathione lyase activity
GTF71_RS17650	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GTF71_RS17655	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GTF71_RS17660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GTF71_RS17665	COG0363	glucosamine-6-phosphate deaminase activity
GTF71_RS17670	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GTF71_RS17695	COG1929	Belongs to the glycerate kinase type-1 family
GTF71_RS17700	COG2610	gluconate transmembrane transporter activity
GTF71_RS17705	COG3835	regulator
GTF71_RS17715	COG0748	coenzyme F420 binding
GTF71_RS17720	COG3721	Heme iron utilization protein
GTF71_RS17730	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GTF71_RS17735	COG0811	peptide transport
GTF71_RS17740	COG0848	biopolymer transport protein
GTF71_RS17745	COG4558	Periplasmic binding protein
GTF71_RS17750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GTF71_RS17755	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GTF71_RS17790	COG0633	Ferredoxin
GTF71_RS17790	COG3217	Mosc domain protein beta barrel domain protein
GTF71_RS17790	COG3217	Mosc domain protein beta barrel domain protein
GTF71_RS17790	COG0633	Ferredoxin
GTF71_RS17795	COG0418	dihydroorotase activity
GTF71_RS17805	COG3152	Membrane
GTF71_RS17815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GTF71_RS17820	COG2354	Protein conserved in bacteria
GTF71_RS17830	COG1278	Cold shock
GTF71_RS17855	COG3706	GGDEF domain
GTF71_RS17860	COG1349	DNA-binding transcription factor activity
GTF71_RS17875	COG3833	ABC-type maltose transport systems, permease component
GTF71_RS17880	COG1175	transmembrane transport
GTF71_RS17890	COG3842	ATPase activity
GTF71_RS17895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GTF71_RS17910	COG0393	Putative heavy-metal-binding
GTF71_RS17920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GTF71_RS17925	COG0835	chemotaxis
GTF71_RS17925	COG0784	Response regulator, receiver
GTF71_RS17930	COG1846	Transcriptional regulator
GTF71_RS17935	COG3706	GGDEF domain
GTF71_RS17975	COG5001	Diguanylate cyclase
GTF71_RS17985	COG1741	Belongs to the pirin family
GTF71_RS17990	COG3123	guanosine phosphorylase activity
GTF71_RS18000	COG2211	Major facilitator Superfamily
GTF71_RS18005	COG0840	transmembrane signaling receptor activity
GTF71_RS18010	COG1067	ATP-dependent peptidase activity
GTF71_RS18020	COG4172	Belongs to the ABC transporter superfamily
GTF71_RS18045	COG0583	DNA-binding transcription factor activity
GTF71_RS18055	COG1620	l-lactate permease
GTF71_RS18070	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GTF71_RS18080	COG0840	transmembrane signaling receptor activity
GTF71_RS18090	COG0513	Belongs to the DEAD box helicase family
GTF71_RS18095	COG0583	DNA-binding transcription factor activity
GTF71_RS18105	COG1902	pentaerythritol trinitrate reductase activity
GTF71_RS18115	COG1132	(ABC) transporter
GTF71_RS18125	COG1902	pentaerythritol trinitrate reductase activity
GTF71_RS18135	COG1280	lysine exporter protein (LysE YggA)
GTF71_RS18140	COG2207	Transcriptional regulator
GTF71_RS18160	COG1846	Transcriptional regulator
GTF71_RS18165	COG1764	response to oxidative stress
GTF71_RS18170	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GTF71_RS18175	COG0697	spore germination
GTF71_RS18185	COG0700	Nucleoside recognition
GTF71_RS18190	COG3366	ferrous iron transmembrane transporter activity
GTF71_RS18195	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GTF71_RS18205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GTF71_RS18210	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GTF71_RS18215	COG2259	Doxx family
GTF71_RS18240	COG0363	glucosamine-6-phosphate deaminase activity
GTF71_RS18255	COG4580	involved in the transport of maltose and maltodextrins
GTF71_RS18270	COG0840	transmembrane signaling receptor activity
GTF71_RS18285	COG0840	transmembrane signaling receptor activity
GTF71_RS18295	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GTF71_RS18300	COG1126	abc transporter atp-binding protein
GTF71_RS18310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GTF71_RS18315	COG4597	amino acid ABC transporter
GTF71_RS18320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GTF71_RS18330	COG0739	heme binding
GTF71_RS18335	COG2213	PTS system mannitol-specific
GTF71_RS18335	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GTF71_RS18340	COG0246	Mannitol dehydrogenase
GTF71_RS18345	COG3722	fumarate hydratase activity
GTF71_RS18350	COG0673	inositol 2-dehydrogenase activity
GTF71_RS18380	COG2910	NAD(P)H-binding
GTF71_RS18390	COG0840	transmembrane signaling receptor activity
GTF71_RS18395	COG4221	oxidoreductase activity
GTF71_RS18405	COG1901	pseudouridine methyltransferase
GTF71_RS18420	COG0531	amino acid
GTF71_RS18425	COG1982	Orn Lys Arg decarboxylase major
GTF71_RS18455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GTF71_RS18480	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GTF71_RS18520	COG0745	RESPONSE REGULATOR receiver
GTF71_RS18545	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GTF71_RS18550	COG0840	transmembrane signaling receptor activity
GTF71_RS18555	COG0835	chemotaxis
GTF71_RS18560	COG0835	chemotaxis
GTF71_RS18565	COG2198	Histidine kinase
GTF71_RS18565	COG0643	Histidine kinase
GTF71_RS18585	COG0601	transmembrane transport
GTF71_RS18590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GTF71_RS18600	COG2194	sulfuric ester hydrolase activity
GTF71_RS18605	COG0642	Histidine kinase
GTF71_RS18610	COG0745	RESPONSE REGULATOR receiver
GTF71_RS18640	COG1444	tRNA N-acetyltransferase activity
GTF71_RS18645	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine