locus-tag	class	description
N900_RS00010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N900_RS00015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
N900_RS00020	COG0706	membrane insertase activity
N900_RS00030	COG0594	ribonuclease P activity
N900_RS00035	COG0230	Belongs to the bacterial ribosomal protein bL34 family
N900_RS00040	COG1126	abc transporter atp-binding protein
N900_RS00055	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
N900_RS00060	COG0592	DNA-directed DNA polymerase activity
N900_RS00065	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N900_RS00070	COG0187	DNA topoisomerase II activity
N900_RS00085	COG0071	Belongs to the small heat shock protein (HSP20) family
N900_RS00090	COG3977	Valine--pyruvate aminotransferase
N900_RS00095	COG0751	glycine-tRNA ligase activity
N900_RS00100	COG0752	glycyl-tRNA synthetase alpha subunit
N900_RS00105	COG2119	membrane
N900_RS00115	COG0425	Belongs to the sulfur carrier protein TusA family
N900_RS00125	COG0604	alcohol dehydrogenase
N900_RS00135	COG0129	dihydroxy-acid dehydratase activity
N900_RS00140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N900_RS00155	COG0606	chelatase, subunit chli
N900_RS00160	COG0204	Acyl-transferase
N900_RS00165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N900_RS00170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N900_RS00180	COG3084	Protein conserved in bacteria
N900_RS00190	COG4326	sporulation control protein
N900_RS00195	COG1272	protein, Hemolysin III
N900_RS00205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N900_RS00210	COG0569	domain protein
N900_RS00215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N900_RS00215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N900_RS00220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N900_RS00225	COG0242	peptide deformylase activity
N900_RS00230	COG1652	LysM domain
N900_RS00235	COG0758	DNA mediated transformation
N900_RS00240	COG2922	Belongs to the Smg family
N900_RS00245	COG0551	DNA topoisomerase type I activity
N900_RS00250	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N900_RS00255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
N900_RS00260	COG0009	L-threonylcarbamoyladenylate synthase
N900_RS00265	COG0408	coproporphyrinogen oxidase activity
N900_RS00270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N900_RS00280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N900_RS00320	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N900_RS00325	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
N900_RS00335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N900_RS00340	COG2104	thiamine diphosphate biosynthetic process
N900_RS00345	COG2022	thiamine diphosphate biosynthetic process
N900_RS00350	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N900_RS00355	COG0006	proline dipeptidase activity
N900_RS00355	COG0006	proline dipeptidase activity
N900_RS00375	COG1522	sequence-specific DNA binding
N900_RS00380	COG5002	protein histidine kinase activity
N900_RS00380	COG5001	Diguanylate cyclase
N900_RS00400	COG0589	response to stress
N900_RS00410	COG1528	Iron-storage protein
N900_RS00420	COG2081	HI0933 family
N900_RS00430	COG1322	Protein conserved in bacteria
N900_RS00435	COG2226	methyltransferase
N900_RS00450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N900_RS00455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N900_RS00460	COG0805	protein transport
N900_RS00465	COG1858	cytochrome C peroxidase
N900_RS00470	COG0534	Mate efflux family protein
N900_RS00480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N900_RS00490	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
N900_RS00495	COG3161	chorismate lyase activity
N900_RS00505	COG1580	Controls the rotational direction of flagella during chemotaxis
N900_RS00510	COG0840	transmembrane signaling receptor activity
N900_RS00520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N900_RS00530	COG0084	hydrolase, TatD family'
N900_RS00545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N900_RS00545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N900_RS00565	COG3078	GTPase activator activity
N900_RS00580	COG3071	HemY protein
N900_RS00585	COG2959	enzyme of heme biosynthesis
N900_RS00590	COG1587	Uroporphyrinogen-III synthase
N900_RS00595	COG0181	hydroxymethylbilane synthase activity
N900_RS00610	COG1965	Belongs to the frataxin family
N900_RS00620	COG0019	diaminopimelate decarboxylase activity
N900_RS00625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N900_RS00635	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
N900_RS00640	COG1011	Hydrolase
N900_RS00645	COG2200	EAL domain
N900_RS00645	COG2199	diguanylate cyclase activity
N900_RS00645	COG3287	FIST C domain
N900_RS00665	COG0561	phosphatase activity
N900_RS00670	COG2267	carboxylic ester hydrolase activity
N900_RS00675	COG1280	lysine exporter protein (LysE YggA)
N900_RS00680	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N900_RS00685	COG0783	Belongs to the Dps family
N900_RS00720	COG0742	ribosomal rna small subunit methyltransferase
N900_RS00725	COG0552	protein localization to endoplasmic reticulum
N900_RS00730	COG2884	Cell division ATP-binding protein ftsE
N900_RS00735	COG2177	Part of the ABC transporter FtsEX involved in
N900_RS00740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N900_RS00745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N900_RS00760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N900_RS00765	COG4206	TonB-dependent receptor
N900_RS00770	COG1404	Belongs to the peptidase S8 family
N900_RS00775	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N900_RS00810	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N900_RS00815	COG5001	Diguanylate cyclase
N900_RS00815	COG3300	MHYT domain
N900_RS00825	COG3852	Histidine kinase
N900_RS00835	COG0174	glutamine synthetase
N900_RS00845	COG1217	gtp-binding protein TYPA
N900_RS00855	COG1295	ribonuclease BN
N900_RS00860	COG1490	D-aminoacyl-tRNA deacylase activity
N900_RS00865	COG0456	acetyltransferase
N900_RS00875	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
N900_RS00880	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
N900_RS00885	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N900_RS00890	COG3031	protein transport across the cell outer membrane
N900_RS00900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N900_RS00905	COG1459	type II secretion system
N900_RS00910	COG2165	general secretion pathway protein
N900_RS00915	COG2165	general secretion pathway protein
N900_RS00920	COG2165	general secretion pathway protein
N900_RS00925	COG4795	General secretion pathway protein
N900_RS00930	COG3156	type II secretion system protein K
N900_RS00935	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
N900_RS00940	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
N900_RS00950	COG1218	3'(2'),5'-bisphosphate nucleotidase
N900_RS00955	COG0494	nUDIX hydrolase
N900_RS00965	COG1040	competence protein
N900_RS00970	COG0596	Alpha beta hydrolase
N900_RS00980	COG2183	response to ionizing radiation
N900_RS00985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N900_RS01000	COG2233	PERMEase
N900_RS01005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N900_RS01010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N900_RS01015	COG1758	RNA polymerase activity
N900_RS01020	COG0194	GDP metabolic process
N900_RS01025	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N900_RS01030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N900_RS01050	COG4232	protein-disulfide reductase activity
N900_RS01065	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
N900_RS01070	COG1027	Aspartate ammonia-lyase
N900_RS01075	COG3706	GGDEF domain
N900_RS01080	COG3030	protein affecting phage T7 exclusion by the F plasmid
N900_RS01085	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N900_RS01095	COG2205	protein histidine kinase activity
N900_RS01100	COG0745	RESPONSE REGULATOR receiver
N900_RS01110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N900_RS01115	COG0205	6-phosphofructokinase activity
N900_RS01120	COG1494	fructose-1,6-bisphosphatase
N900_RS01125	COG3074	FtsZ-dependent cytokinesis
N900_RS01130	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N900_RS01135	COG0460	homoserine dehydrogenase
N900_RS01135	COG0527	aspartate kinase activity
N900_RS01140	COG0626	cystathionine gamma-synthase activity
N900_RS01145	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
N900_RS01150	COG0281	malic enzyme
N900_RS01155	COG0254	rRNA binding
N900_RS01160	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N900_RS01165	COG1609	Transcriptional regulator
N900_RS01170	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N900_RS01175	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
N900_RS01180	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
N900_RS01185	COG1575	Belongs to the MenA family. Type 1 subfamily
N900_RS01190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N900_RS01195	COG0534	Mate efflux family protein
N900_RS01200	COG0149	triose-phosphate isomerase activity
N900_RS01225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
N900_RS01230	COG0459	protein refolding
N900_RS01240	COG1509	lysine 2,3-aminomutase activity
N900_RS01245	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N900_RS01255	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
N900_RS01260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N900_RS01265	COG1053	succinate dehydrogenase
N900_RS01270	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
N900_RS01275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N900_RS01280	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
N900_RS01285	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N900_RS01290	COG1045	serine acetyltransferase
N900_RS01300	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
N900_RS01305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N900_RS01310	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
N900_RS01315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
N900_RS01320	COG0137	argininosuccinate synthase activity
N900_RS01325	COG0165	Argininosuccinate lyase
N900_RS01335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N900_RS01340	COG0678	peroxiredoxin activity
N900_RS01340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N900_RS01350	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
N900_RS01380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N900_RS01385	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N900_RS01395	COG0338	D12 class N6 adenine-specific DNA methyltransferase
N900_RS01400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N900_RS01405	COG0546	phosphoglycolate phosphatase activity
N900_RS01410	COG0180	Tryptophanyl-tRNA synthetase
N900_RS01425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N900_RS01435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N900_RS01445	COG1012	belongs to the aldehyde dehydrogenase family
N900_RS01460	COG3954	Phosphoribulokinase
N900_RS01470	COG0429	hydrolase of the alpha beta-hydrolase fold
N900_RS01480	COG0488	(ABC) transporter
N900_RS01485	COG2249	NAD(P)H dehydrogenase (quinone) activity
N900_RS01500	COG1047	Peptidyl-prolyl cis-trans
N900_RS01515	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
N900_RS01520	COG3083	sulfuric ester hydrolase activity
N900_RS01525	COG0557	exoribonuclease II activity
N900_RS01530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N900_RS01535	COG0051	transcription antitermination factor activity, RNA binding
N900_RS01540	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N900_RS01545	COG0088	Forms part of the polypeptide exit tunnel
N900_RS01550	COG0089	rRNA binding
N900_RS01555	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N900_RS01560	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
N900_RS01565	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
N900_RS01570	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
N900_RS01575	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
N900_RS01580	COG0255	Belongs to the universal ribosomal protein uL29 family
N900_RS01585	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N900_RS01590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
N900_RS01595	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
N900_RS01600	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N900_RS01605	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N900_RS01610	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N900_RS01620	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
N900_RS01625	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N900_RS01630	COG1841	ribosomal large subunit assembly
N900_RS01640	COG0201	protein transport
N900_RS01645	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N900_RS01650	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N900_RS01655	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
N900_RS01660	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N900_RS01665	COG0202	RNA polymerase activity
N900_RS01670	COG0203	ribosomal protein L17
N900_RS01680	COG0545	Peptidyl-prolyl cis-trans isomerase
N900_RS01685	COG3061	Opacity-associated protein A
N900_RS01685	COG3266	domain, Protein
N900_RS01690	COG0697	spore germination
N900_RS01695	COG2153	protein acetylation
N900_RS01700	COG0513	Belongs to the DEAD box helicase family
N900_RS01710	COG0737	Belongs to the 5'-nucleotidase family
N900_RS01715	COG1648	precorrin-2 dehydrogenase activity
N900_RS01715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N900_RS01730	COG0529	Catalyzes the synthesis of activated sulfate
N900_RS01750	COG1136	(ABC) transporter
N900_RS01765	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
N900_RS01770	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N900_RS01775	COG0729	surface antigen
N900_RS01785	COG2105	PFAM AIG2 family protein
N900_RS01790	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N900_RS01805	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N900_RS01810	COG0163	prenyltransferase activity
N900_RS01820	COG1178	ABC-type Fe3 transport system permease component
N900_RS01825	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
N900_RS01830	COG3028	Belongs to the UPF0307 family
N900_RS01835	COG0312	modulator of DNA gyrase
N900_RS01840	COG2239	Acts as a magnesium transporter
N900_RS01845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N900_RS01850	COG1660	Displays ATPase and GTPase activities
N900_RS01855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N900_RS01860	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N900_RS01870	COG1137	ATPase activity
N900_RS01875	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
N900_RS01890	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N900_RS01890	COG0517	IMP dehydrogenase activity
N900_RS01905	COG1127	ABC transporter
N900_RS01910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
N900_RS01915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N900_RS01920	COG2854	intermembrane phospholipid transfer
N900_RS01930	COG5007	Belongs to the BolA IbaG family
N900_RS01935	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N900_RS01945	COG0251	oxidation-reduction process
N900_RS01955	COG0540	Belongs to the ATCase OTCase family
N900_RS01970	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
N900_RS01985	COG0564	pseudouridine synthase activity
N900_RS01990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N900_RS01995	COG0525	valine-tRNA ligase activity
N900_RS02000	COG2927	DNA polymerase III (CHI subunit)
N900_RS02005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N900_RS02010	COG0795	lipopolysaccharide-transporting ATPase activity
N900_RS02015	COG0795	lipopolysaccharide-transporting ATPase activity
N900_RS02030	COG3437	response regulator, receiver
N900_RS02075	COG0066	3-isopropylmalate dehydratase activity
N900_RS02080	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
N900_RS02085	COG0473	3-isopropylmalate dehydrogenase activity
N900_RS02110	COG0583	DNA-binding transcription factor activity
N900_RS02115	COG1022	Amp-dependent synthetase and ligase
N900_RS02120	COG0028	Belongs to the TPP enzyme family
N900_RS02125	COG0440	acetolactate synthase activity
N900_RS02130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N900_RS02135	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
N900_RS02140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N900_RS02145	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
N900_RS02150	COG3079	Belongs to the UPF0149 family
N900_RS02155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N900_RS02160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N900_RS02175	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
N900_RS02185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N900_RS02195	COG1595	DNA-templated transcription, initiation
N900_RS02210	COG3086	response to oxidative stress
N900_RS02215	COG0481	GTPase activity
N900_RS02230	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N900_RS02235	COG1381	Involved in DNA repair and RecF pathway recombination
N900_RS02240	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
N900_RS02260	COG5001	Diguanylate cyclase
N900_RS02275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N900_RS02280	COG3956	TIGRFAM MazG family protein
N900_RS02285	COG0504	CTP synthase activity
N900_RS02290	COG0148	phosphopyruvate hydratase activity
N900_RS02300	COG3267	Type II secretory pathway component ExeA
N900_RS02300	COG3409	Peptidoglycan-binding domain 1 protein
N900_RS02310	COG4991	sh3 domain protein
N900_RS02315	COG0306	phosphate transporter
N900_RS02320	COG1392	Phosphate transport regulator
N900_RS02325	COG3025	triphosphatase activity
N900_RS02330	COG0840	transmembrane signaling receptor activity
N900_RS02335	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
N900_RS02345	COG1538	Outer membrane efflux protein
N900_RS02350	COG0494	nUDIX hydrolase
N900_RS02355	COG3151	Protein conserved in bacteria
N900_RS02365	COG3150	esterase
N900_RS02370	COG0187	DNA topoisomerase II activity
N900_RS02375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N900_RS02385	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
N900_RS02390	COG0237	dephospho-CoA kinase activity
N900_RS02400	COG1459	type II secretion system
N900_RS02405	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N900_RS02425	COG0716	FMN binding
N900_RS02430	COG4974	Belongs to the 'phage' integrase family
N900_RS02435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N900_RS02440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N900_RS02445	COG0737	Belongs to the 5'-nucleotidase family
N900_RS02450	COG2186	Transcriptional regulator
N900_RS02455	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
N900_RS02460	COG0508	dehydrogenase complex catalyzes the overall conversion of
N900_RS02465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N900_RS02475	COG3116	cell division
N900_RS02480	COG0768	penicillin binding
N900_RS02485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N900_RS02490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N900_RS02500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N900_RS02505	COG0772	Belongs to the SEDS family
N900_RS02515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N900_RS02520	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N900_RS02525	COG0849	cell division
N900_RS02530	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N900_RS02535	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
N900_RS02545	COG0653	protein targeting
N900_RS02555	COG0494	nUDIX hydrolase
N900_RS02560	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N900_RS02570	COG0505	Belongs to the CarA family
N900_RS02575	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N900_RS02595	COG4172	Belongs to the ABC transporter superfamily
N900_RS02605	COG0730	response to heat
N900_RS02610	COG0583	DNA-binding transcription factor activity
N900_RS02615	COG2860	membrane
N900_RS02620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N900_RS02630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N900_RS02640	COG0493	'glutamate synthase
N900_RS02645	COG0070	glutamate synthase
N900_RS02645	COG0069	glutamate synthase activity
N900_RS02645	COG0067	glutamate synthase
N900_RS02655	COG0067	glutamate synthase
N900_RS02655	COG0069	glutamate synthase activity
N900_RS02655	COG0070	glutamate synthase
N900_RS02660	COG1242	4 iron, 4 sulfur cluster binding
N900_RS02665	COG3706	GGDEF domain
N900_RS02665	COG5001	Diguanylate cyclase
N900_RS02665	COG4251	negative regulation of phosphorylation
N900_RS02665	COG2203	Gaf domain
N900_RS02670	COG2198	Histidine kinase
N900_RS02670	COG0784	Response regulator, receiver
N900_RS02670	COG5002	protein histidine kinase activity
N900_RS02675	COG0745	RESPONSE REGULATOR receiver
N900_RS02685	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N900_RS02705	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N900_RS02710	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
N900_RS02715	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
N900_RS02720	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N900_RS02735	COG1115	amino acid carrier protein
N900_RS02740	COG3022	response to hydroperoxide
N900_RS02745	COG0084	hydrolase, TatD family'
N900_RS02750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N900_RS02760	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N900_RS02765	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
N900_RS02770	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
N900_RS02775	COG0813	purine-nucleoside phosphorylase activity
N900_RS02785	COG0560	Phosphoserine phosphatase
N900_RS02795	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
N900_RS02800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N900_RS02805	COG1022	Amp-dependent synthetase and ligase
N900_RS02820	COG3250	beta-galactosidase activity
N900_RS02825	COG1609	Transcriptional regulator
N900_RS02830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N900_RS02845	COG0189	ligase activity
N900_RS02845	COG0569	domain protein
N900_RS02850	COG0456	acetyltransferase
N900_RS02860	COG2171	N-acyltransferase activity
N900_RS02865	COG3141	response to X-ray
N900_RS02880	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
N900_RS02885	COG1074	ATP-dependent DNA helicase activity
N900_RS02890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N900_RS02905	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
N900_RS02905	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
N900_RS02915	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
N900_RS02920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N900_RS02925	COG2166	iron-sulfur cluster assembly
N900_RS02930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N900_RS02935	COG0693	protein deglycase activity
N900_RS02940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N900_RS02945	COG3248	Nucleoside-binding outer membrane protein
N900_RS02955	COG1595	DNA-templated transcription, initiation
N900_RS02965	COG2211	Major facilitator Superfamily
N900_RS02970	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N900_RS02980	COG2813	Specifically methylates the guanine in position
N900_RS02985	COG0271	Belongs to the BolA IbaG family
N900_RS02990	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
N900_RS02995	COG1805	sodium ion transport
N900_RS03000	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
N900_RS03005	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
N900_RS03010	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
N900_RS03015	COG2871	sodium ion transport
N900_RS03020	COG1477	protein flavinylation
N900_RS03050	COG3328	transposase activity
N900_RS03055	COG3706	GGDEF domain
N900_RS03060	COG0733	neurotransmitter:sodium symporter activity
N900_RS03070	COG0189	ligase activity
N900_RS03075	COG4067	protein conserved in archaea
N900_RS03075	COG0189	ligase activity
N900_RS03080	COG2195	Cleaves the N-terminal amino acid of tripeptides
N900_RS03085	COG2252	PERMEase
N900_RS03090	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
N900_RS03095	COG1073	alpha beta
N900_RS03105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N900_RS03110	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N900_RS03115	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N900_RS03120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N900_RS03120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N900_RS03135	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N900_RS03140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N900_RS03145	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N900_RS03150	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N900_RS03160	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
N900_RS03165	COG0024	Methionine aminopeptidase
N900_RS03170	COG0052	Belongs to the universal ribosomal protein uS2 family
N900_RS03175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N900_RS03180	COG0528	UMP kinase activity
N900_RS03185	COG0233	cytoplasmic translational termination
N900_RS03190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N900_RS03195	COG0575	Belongs to the CDS family
N900_RS03200	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
N900_RS03205	COG0750	zinc metalloprotease
N900_RS03215	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
N900_RS03220	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N900_RS03225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N900_RS03230	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N900_RS03235	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N900_RS03240	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N900_RS03250	COG0825	malonyl-CoA metabolic process
N900_RS03255	COG0037	tRNA processing
N900_RS03265	COG3479	Phenolic acid decarboxylase
N900_RS03270	COG0347	Belongs to the P(II) protein family
N900_RS03275	COG3021	interspecies interaction between organisms
N900_RS03280	COG1388	LysM domain
N900_RS03280	COG0741	lytic transglycosylase activity
N900_RS03285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N900_RS03290	COG2226	methyltransferase
N900_RS03295	COG0328	RNA-DNA hybrid ribonuclease activity
N900_RS03310	COG1960	acyl-CoA dehydrogenase activity
N900_RS03315	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
N900_RS03320	COG0121	glutamine amidotransferase
N900_RS03325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N900_RS03330	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N900_RS03335	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
N900_RS03345	COG1187	pseudouridine synthase activity
N900_RS03350	COG2840	Smr protein MutS2
N900_RS03365	COG3735	TraB family
N900_RS03380	COG2217	Heavy metal translocating P-type atpase
N900_RS03380	COG2608	mercury ion transmembrane transporter activity
N900_RS03385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N900_RS03400	COG1629	transport
N900_RS03400	COG4774	siderophore transport
N900_RS03405	COG2375	cellular response to nickel ion
N900_RS03410	COG3433	isochorismatase activity
N900_RS03410	COG2226	methyltransferase
N900_RS03410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N900_RS03445	COG0835	chemotaxis
N900_RS03445	COG0784	Response regulator, receiver
N900_RS03450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N900_RS03455	COG1815	bacterial-type flagellum-dependent cell motility
N900_RS03470	COG1749	Flagellar hook protein flgE
N900_RS03475	COG4787	bacterial-type flagellum-dependent cell motility
N900_RS03485	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
N900_RS03490	COG1706	bacterial-type flagellum-dependent cell motility
N900_RS03495	COG1705	Flagellar rod assembly protein muramidase FlgJ
N900_RS03495	COG3951	Flagellar rod assembly protein muramidase FlgJ
N900_RS03515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N900_RS03520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N900_RS03550	COG0012	GTP binding
N900_RS03555	COG0193	aminoacyl-tRNA hydrolase activity
N900_RS03560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N900_RS03565	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
N900_RS03570	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
N900_RS03575	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N900_RS03580	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N900_RS03585	COG2890	protein-(glutamine-N5) methyltransferase activity
N900_RS03595	COG2912	Transglutaminase-like superfamily
N900_RS03600	COG2877	3-deoxy-8-phosphooctulonate synthase activity
N900_RS03605	COG0737	Belongs to the 5'-nucleotidase family
N900_RS03610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N900_RS03615	COG2233	PERMEase
N900_RS03635	COG1393	Belongs to the ArsC family
N900_RS03640	COG4783	chaperone-mediated protein folding
N900_RS03660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N900_RS03675	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
N900_RS03685	COG1876	peptidase activity
N900_RS03695	COG1393	Belongs to the ArsC family
N900_RS03715	COG2837	iron assimilation
N900_RS03720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N900_RS03725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N900_RS03730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N900_RS03735	COG1334	flagellar protein FlaG
N900_RS03740	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
N900_RS03750	COG1516	flagellar protein fliS
N900_RS03770	COG1677	Flagellar hook-basal body complex protein FliE
N900_RS03780	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N900_RS03785	COG1317	bacterial-type flagellum organization
N900_RS03805	COG1580	Controls the rotational direction of flagella during chemotaxis
N900_RS03830	COG1987	bacterial-type flagellum assembly
N900_RS03835	COG1684	flagellar biosynthetic protein fliR
N900_RS03845	COG2840	Smr protein MutS2
N900_RS03850	COG2890	protein-(glutamine-N5) methyltransferase activity
N900_RS03860	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N900_RS03865	COG2860	membrane
N900_RS03870	COG3101	peptidyl-lysine hydroxylation
N900_RS03880	COG0431	NADPH-dependent FMN reductase
N900_RS03890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N900_RS03895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N900_RS03900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N900_RS03905	COG0735	belongs to the Fur family
N900_RS03915	COG0583	DNA-binding transcription factor activity
N900_RS03925	COG1346	cytolysis
N900_RS03940	COG0596	Alpha beta hydrolase
N900_RS03945	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
N900_RS03950	COG0033	Phosphoglucomutase
N900_RS03960	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N900_RS03965	COG0372	Belongs to the citrate synthase family
N900_RS03970	COG2009	succinate dehydrogenase
N900_RS03975	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
N900_RS03980	COG1053	succinate dehydrogenase
N900_RS03990	COG0567	Dehydrogenase, E1 component
N900_RS03995	COG0508	dehydrogenase complex catalyzes the overall conversion of
N900_RS04000	COG0045	succinate-CoA ligase (ADP-forming) activity
N900_RS04010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N900_RS04015	COG1121	(ABC) transporter
N900_RS04020	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
N900_RS04025	COG4977	sequence-specific DNA binding
N900_RS04030	COG1918	ferrous iron import across plasma membrane
N900_RS04050	COG0018	arginyl-trna synthetase
N900_RS04060	COG1025	Belongs to the peptidase M16 family
N900_RS04065	COG2062	phosphohistidine phosphatase, SixA
N900_RS04095	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
N900_RS04100	COG2198	Histidine kinase
N900_RS04100	COG0784	Response regulator, receiver
N900_RS04100	COG0643	Histidine kinase
N900_RS04105	COG2201	protein-glutamate methylesterase activity
N900_RS04110	COG1192	Involved in chromosome partitioning
N900_RS04120	COG0835	chemotaxis
N900_RS04130	COG4133	protoheme IX ABC transporter activity
N900_RS04135	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N900_RS04140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N900_RS04150	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
N900_RS04155	COG1138	Cytochrome C-type biogenesis protein
N900_RS04160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N900_RS04165	COG4235	cytochrome complex assembly
N900_RS04165	COG3088	subunit of a heme lyase
N900_RS04175	COG2853	Lipoprotein
N900_RS04195	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
N900_RS04200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N900_RS04205	COG0123	including yeast histone deacetylase and acetoin utilization protein
N900_RS04220	COG3083	sulfuric ester hydrolase activity
N900_RS04225	COG3082	Protein of unknown function (DUF1414)
N900_RS04230	COG3081	Nucleoid-associated protein
N900_RS04240	COG1757	Na H antiporter
N900_RS04245	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N900_RS04250	COG2095	MarC family integral membrane protein
N900_RS04255	COG1454	alcohol dehydrogenase
N900_RS04255	COG1012	belongs to the aldehyde dehydrogenase family
N900_RS04265	COG0659	secondary active sulfate transmembrane transporter activity
N900_RS04270	COG1530	ribonuclease E activity
N900_RS04285	COG0564	pseudouridine synthase activity
N900_RS04290	COG0424	maF-like protein
N900_RS04295	COG1399	metal-binding, possibly nucleic acid-binding protein
N900_RS04300	COG0333	Belongs to the bacterial ribosomal protein bL32 family
N900_RS04305	COG0416	fatty acid biosynthetic process
N900_RS04310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N900_RS04320	COG1028	Short-chain dehydrogenase reductase Sdr
N900_RS04325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N900_RS04330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N900_RS04335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N900_RS04340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N900_RS04345	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N900_RS04355	COG0084	hydrolase, TatD family'
N900_RS04360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N900_RS04360	COG1263	PTS System
N900_RS04365	COG0733	neurotransmitter:sodium symporter activity
N900_RS04375	COG4667	esterase of the alpha-beta hydrolase superfamily
N900_RS04385	COG1940	carbohydrate kinase activity
N900_RS04390	COG0784	Response regulator, receiver
N900_RS04390	COG0835	chemotaxis
N900_RS04405	COG2226	methyltransferase
N900_RS04415	COG0676	glucose-6-phosphate 1-epimerase activity
N900_RS04420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N900_RS04425	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N900_RS04435	COG3139	Protein of unknown function (DUF1315)
N900_RS04440	COG0252	asparaginase activity
N900_RS04445	COG0616	signal peptide processing
N900_RS04450	COG1902	pentaerythritol trinitrate reductase activity
N900_RS04450	COG0446	pyridine nucleotide-disulphide oxidoreductase
N900_RS04455	COG0788	formyltetrahydrofolate deformylase activity
N900_RS04465	COG1199	ATP-dependent helicase activity
N900_RS04470	COG1214	PFAM Peptidase M22, glycoprotease
N900_RS04485	COG0596	Alpha beta hydrolase
N900_RS04490	COG0318	PFAM AMP-dependent synthetase and ligase
N900_RS04495	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
N900_RS04515	COG0232	Belongs to the dGTPase family. Type 2 subfamily
N900_RS04520	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
N900_RS04525	COG0436	Aminotransferase
N900_RS04530	COG1169	isochorismate synthase
N900_RS04535	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
N900_RS04540	COG0596	Alpha beta hydrolase
N900_RS04560	COG3135	benzoate transporter
N900_RS04565	COG1396	sequence-specific DNA binding
N900_RS04570	COG0840	transmembrane signaling receptor activity
N900_RS04580	COG0477	Major facilitator Superfamily
N900_RS04600	COG3015	lipoprotein NlpE involved in copper resistance
N900_RS04605	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
N900_RS04610	COG2894	cell division
N900_RS04615	COG0850	regulation of cytokinetic process
N900_RS04620	COG3100	YcgL domain-containing protein
N900_RS04625	COG2951	lytic endotransglycosylase activity
N900_RS04635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N900_RS04640	COG3325	Belongs to the glycosyl hydrolase 18 family
N900_RS04640	COG3469	chitinase activity
N900_RS04645	COG3005	denitrification pathway
N900_RS04650	COG0243	molybdopterin cofactor binding
N900_RS04665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N900_RS04675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N900_RS04710	COG4589	Belongs to the CDS family
N900_RS04720	COG5001	Diguanylate cyclase
N900_RS04720	COG3300	MHYT domain
N900_RS04735	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
N900_RS04740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N900_RS04745	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
N900_RS04750	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N900_RS04760	COG4191	Histidine kinase
N900_RS04770	COG0544	peptidyl-prolyl cis-trans isomerase activity
N900_RS04780	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N900_RS04785	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N900_RS04790	COG0776	regulation of translation
N900_RS04795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N900_RS04800	COG1555	photosystem II stabilization
N900_RS04805	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N900_RS04810	COG0539	negative regulation of cytoplasmic translation
N900_RS04815	COG0776	regulation of translation
N900_RS04820	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
N900_RS04825	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
N900_RS04845	COG0583	DNA-binding transcription factor activity
N900_RS04855	COG0686	Belongs to the AlaDH PNT family
N900_RS04865	COG1674	ftsk spoiiie
N900_RS04870	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
N900_RS04875	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
N900_RS04880	COG2186	Transcriptional regulator
N900_RS04895	COG0537	adenosine 5'-monophosphoramidase activity
N900_RS04920	COG3150	esterase
N900_RS04925	COG1252	NADH dehydrogenase
N900_RS04945	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N900_RS04955	COG4591	ABC-type transport system involved in lipoprotein release permease component
N900_RS04960	COG1136	(ABC) transporter
N900_RS04965	COG4591	ABC-type transport system involved in lipoprotein release permease component
N900_RS04975	COG0658	competence protein
N900_RS04975	COG2333	competence protein COMEC
N900_RS04980	COG1132	(ABC) transporter
N900_RS04985	COG1663	tetraacyldisaccharide 4'-kinase activity
N900_RS04990	COG2835	tetraacyldisaccharide 4'-kinase activity
N900_RS04995	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
N900_RS05000	COG2719	SpoVR family
N900_RS05005	COG2718	Belongs to the UPF0229 family
N900_RS05010	COG2766	serine protein kinase
N900_RS05015	COG3013	Belongs to the UPF0304 family
N900_RS05025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
N900_RS05030	COG0840	transmembrane signaling receptor activity
N900_RS05040	COG1882	Formate acetyltransferase
N900_RS05065	COG4160	amino acid transport
N900_RS05070	COG0708	Exodeoxyribonuclease III
N900_RS05075	COG0840	transmembrane signaling receptor activity
N900_RS05085	COG3923	Primosomal replication protein n
N900_RS05090	COG0730	response to heat
N900_RS05095	COG1199	ATP-dependent helicase activity
N900_RS05100	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
N900_RS05105	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
N900_RS05110	COG3012	SEC-C Motif Domain Protein
N900_RS05115	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N900_RS05120	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N900_RS05125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N900_RS05130	COG0215	cysteine-tRNA ligase activity
N900_RS05135	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
N900_RS05140	COG0632	four-way junction helicase activity
N900_RS05150	COG1271	oxidase subunit
N900_RS05155	COG1294	oxidase, subunit
N900_RS05160	COG4890	Cyd operon protein YbgT
N900_RS05165	COG3790	cyd operon protein YbgE
N900_RS05170	COG0824	Thioesterase
N900_RS05175	COG0811	peptide transport
N900_RS05190	COG0823	Involved in the tonB-independent uptake of proteins
N900_RS05195	COG2885	chlorophyll binding
N900_RS05205	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N900_RS05215	COG5002	protein histidine kinase activity
N900_RS05215	COG0784	Response regulator, receiver
N900_RS05225	COG1482	cell wall glycoprotein biosynthetic process
N900_RS05230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N900_RS05230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N900_RS05230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N900_RS05235	COG2207	Transcriptional regulator
N900_RS05245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N900_RS05250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N900_RS05255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N900_RS05265	COG1012	belongs to the aldehyde dehydrogenase family
N900_RS05270	COG3284	Transcriptional regulator
N900_RS05275	COG4628	conserved protein (DUF2132)
N900_RS05285	COG0415	Belongs to the DNA photolyase family
N900_RS05355	COG0488	(ABC) transporter
N900_RS05395	COG3941	tape measure
N900_RS05415	COG2003	Belongs to the UPF0758 family
N900_RS05425	COG4409	exo-alpha-(2->6)-sialidase activity
N900_RS05430	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N900_RS05435	COG1940	carbohydrate kinase activity
N900_RS05450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N900_RS05455	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
N900_RS05460	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N900_RS05465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N900_RS05470	COG1737	Transcriptional regulator
N900_RS05475	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
N900_RS05480	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
N900_RS05500	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
N900_RS05520	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
N900_RS05540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N900_RS05550	COG0582	viral genome integration into host DNA
N900_RS05565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N900_RS05575	COG3008	intermembrane lipid transfer
N900_RS05575	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N900_RS05580	COG2995	paraquat-inducible protein a
N900_RS05585	COG0668	transmembrane transport
N900_RS05610	COG1309	transcriptional regulator
N900_RS05615	COG1012	belongs to the aldehyde dehydrogenase family
N900_RS05640	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N900_RS05645	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
N900_RS05675	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N900_RS05680	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N900_RS05685	COG0297	glycogen (starch) synthase activity
N900_RS05705	COG3070	regulator of competence-specific genes
N900_RS05710	COG1609	Transcriptional regulator
N900_RS05715	COG3381	protein complex oligomerization
N900_RS05720	COG0745	RESPONSE REGULATOR receiver
N900_RS05725	COG1434	Gram-negative-bacterium-type cell wall biogenesis
N900_RS05730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N900_RS05740	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
N900_RS05760	COG1032	radical SAM domain protein
N900_RS05765	COG5001	Diguanylate cyclase
N900_RS05770	COG0612	Peptidase, M16
N900_RS05785	COG0583	DNA-binding transcription factor activity
N900_RS05790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N900_RS05800	COG2350	Protein conserved in bacteria
N900_RS05805	COG1607	acyl-coa hydrolase
N900_RS05820	COG1434	Gram-negative-bacterium-type cell wall biogenesis
N900_RS05825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N900_RS05835	COG2116	formate transmembrane transporter activity
N900_RS05845	COG4459	periplasmic nitrate reductase
N900_RS05850	COG3005	denitrification pathway
N900_RS05855	COG0243	molybdopterin cofactor binding
N900_RS05875	COG1227	inorganic diphosphatase activity
N900_RS05890	COG4172	Belongs to the ABC transporter superfamily
N900_RS05905	COG4168	peptide transport system, permease
N900_RS05915	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
N900_RS05920	COG1842	Phage shock protein A
N900_RS05935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N900_RS05950	COG2818	Glycosylase
N900_RS05955	COG0626	cystathionine gamma-synthase activity
N900_RS05965	COG0733	neurotransmitter:sodium symporter activity
N900_RS05970	COG0564	pseudouridine synthase activity
N900_RS05975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N900_RS05980	COG4136	ATPase activity
N900_RS05985	COG4135	transport system, permease component
N900_RS05990	COG4134	Bacterial extracellular solute-binding protein
N900_RS06000	COG3313	Fe-S protein
N900_RS06010	COG0842	Transport permease protein
N900_RS06015	COG1131	(ABC) transporter
N900_RS06020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N900_RS06025	COG0814	amino acid
N900_RS06035	COG2239	Acts as a magnesium transporter
N900_RS06040	COG2205	protein histidine kinase activity
N900_RS06040	COG0784	Response regulator, receiver
N900_RS06085	COG0840	transmembrane signaling receptor activity
N900_RS06100	COG2203	Gaf domain
N900_RS06100	COG3706	GGDEF domain
N900_RS06100	COG5001	Diguanylate cyclase
N900_RS06100	COG4251	negative regulation of phosphorylation
N900_RS06105	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N900_RS06125	COG1061	Type III restriction enzyme res subunit
N900_RS06130	COG1187	pseudouridine synthase activity
N900_RS06135	COG2814	Major facilitator Superfamily
N900_RS06145	COG0702	epimerase
N900_RS06150	COG0534	Mate efflux family protein
N900_RS06155	COG4181	ATPase activity
N900_RS06160	COG0577	efflux transmembrane transporter activity
N900_RS06170	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
N900_RS06180	COG1748	Saccharopine dehydrogenase
N900_RS06195	COG1538	Outer membrane efflux protein
N900_RS06225	COG0583	DNA-binding transcription factor activity
N900_RS06235	COG1451	nucleotide metabolic process
N900_RS06240	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
N900_RS06250	COG3063	Type IV pilus biogenesis stability protein PilW
N900_RS06255	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
N900_RS06275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N900_RS06290	COG3290	protein histidine kinase activity
N900_RS06295	COG4565	transcriptional regulatory protein
N900_RS06305	COG0835	chemotaxis
N900_RS06305	COG0784	Response regulator, receiver
N900_RS06345	COG1085	galactose-1-phosphate uridylyltransferase
N900_RS06350	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
N900_RS06355	COG2017	converts alpha-aldose to the beta-anomer
N900_RS06365	COG2199	diguanylate cyclase activity
N900_RS06365	COG2200	EAL domain
N900_RS06395	COG0753	catalase activity
N900_RS06415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N900_RS06425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N900_RS06465	COG1271	oxidase subunit
N900_RS06470	COG1294	oxidase, subunit
N900_RS06475	COG1136	(ABC) transporter
N900_RS06475	COG4591	ABC-type transport system involved in lipoprotein release permease component
N900_RS06480	COG0577	efflux transmembrane transporter activity
N900_RS06480	COG1136	(ABC) transporter
N900_RS06485	COG1136	(ABC) transporter
N900_RS06485	COG0577	efflux transmembrane transporter activity
N900_RS06505	COG0583	DNA-binding transcription factor activity
N900_RS06515	COG2723	6-phospho-beta-galactosidase activity
N900_RS06520	COG1609	Transcriptional regulator
N900_RS06525	COG0251	oxidation-reduction process
N900_RS06530	COG2731	YhcH YjgK YiaL family protein
N900_RS06535	COG0584	glycerophosphoryl diester phosphodiesterase
N900_RS06540	COG1349	DNA-binding transcription factor activity
N900_RS06545	COG3842	ATPase activity
N900_RS06550	COG0395	ABC-type sugar transport system, permease component
N900_RS06555	COG1175	transmembrane transport
N900_RS06570	COG0811	peptide transport
N900_RS06575	COG0811	peptide transport
N900_RS06580	COG0848	biopolymer transport protein
N900_RS06585	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
N900_RS06595	COG1793	dna ligase
N900_RS06605	COG0534	Mate efflux family protein
N900_RS06615	COG3001	Fructosamine kinase
N900_RS06625	COG0791	NLP P60 protein
N900_RS06630	COG0840	transmembrane signaling receptor activity
N900_RS06640	COG3148	PFAM DTW domain containing protein
N900_RS06645	COG1940	carbohydrate kinase activity
N900_RS06675	COG0746	molybdenum cofactor guanylyltransferase activity
N900_RS06680	COG3842	ATPase activity
N900_RS06685	COG4662	Binding-protein-dependent transport system inner membrane component
N900_RS06695	COG2204	response regulator
N900_RS06700	COG3852	Histidine kinase
N900_RS06705	COG0488	(ABC) transporter
N900_RS06710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N900_RS06740	COG3383	formate dehydrogenase (NAD+) activity
N900_RS06740	COG0243	molybdopterin cofactor binding
N900_RS06745	COG0437	4 iron, 4 sulfur cluster binding
N900_RS06760	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N900_RS06765	COG1666	GTP binding
N900_RS06770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N900_RS06785	COG2996	Protein conserved in bacteria
N900_RS06795	COG3008	intermembrane lipid transfer
N900_RS06800	COG2995	paraquat-inducible protein a
N900_RS06805	COG1132	(ABC) transporter
N900_RS06810	COG1956	GAF domain-containing protein
N900_RS06815	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
N900_RS06830	COG0308	aminopeptidase N
N900_RS06845	COG0167	dihydroorotate dehydrogenase activity
N900_RS06855	COG0116	Belongs to the methyltransferase superfamily
N900_RS06855	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N900_RS06865	COG0488	(ABC) transporter
N900_RS06880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N900_RS06885	COG1067	ATP-dependent peptidase activity
N900_RS06890	COG3120	sequence-specific DNA binding
N900_RS06905	COG3328	transposase activity
N900_RS06985	COG1476	TRANSCRIPTIONal
N900_RS07005	COG1476	TRANSCRIPTIONal
N900_RS07035	COG4128	Pfam Zonular occludens toxin
N900_RS07050	COG1073	alpha beta
N900_RS07050	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
N900_RS07050	COG3064	Membrane
N900_RS07055	COG2994	toxin metabolic process
N900_RS07080	COG2205	protein histidine kinase activity
N900_RS07080	COG0784	Response regulator, receiver
N900_RS07095	COG3278	Belongs to the heme-copper respiratory oxidase family
N900_RS07110	COG2010	Cytochrome c
N900_RS07120	COG2217	Heavy metal translocating P-type atpase
N900_RS07135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N900_RS07140	COG0589	response to stress
N900_RS07165	COG3842	ATPase activity
N900_RS07175	COG1177	transmembrane transport
N900_RS07185	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
N900_RS07200	COG1115	amino acid carrier protein
N900_RS07205	COG1280	lysine exporter protein (LysE YggA)
N900_RS07220	COG3675	Pfam Lipase (class 3)
N900_RS07230	COG3501	Rhs element vgr protein
N900_RS07240	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
N900_RS07250	COG2814	Major facilitator Superfamily
N900_RS07255	COG1566	PFAM secretion protein HlyD family protein
N900_RS07260	COG1538	Outer membrane efflux protein
N900_RS07270	COG0513	Belongs to the DEAD box helicase family
N900_RS07280	COG0840	transmembrane signaling receptor activity
N900_RS07285	COG0840	transmembrane signaling receptor activity
N900_RS07285	COG3290	protein histidine kinase activity
N900_RS07290	COG0835	chemotaxis
N900_RS07295	COG2201	protein-glutamate methylesterase activity
N900_RS07305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N900_RS07310	COG2198	Histidine kinase
N900_RS07310	COG0784	Response regulator, receiver
N900_RS07310	COG0643	Histidine kinase
N900_RS07315	COG0643	Histidine kinase
N900_RS07315	COG2198	Histidine kinase
N900_RS07325	COG0745	RESPONSE REGULATOR receiver
N900_RS07340	COG0415	Belongs to the DNA photolyase family
N900_RS07345	COG0477	Major facilitator Superfamily
N900_RS07350	COG0583	DNA-binding transcription factor activity
N900_RS07360	COG0095	Lipoate-protein ligase
N900_RS07365	COG0443	Heat shock 70 kDa protein
N900_RS07375	COG1643	Atp-dependent helicase
N900_RS07415	COG0443	Heat shock 70 kDa protein
N900_RS07420	COG0443	Heat shock 70 kDa protein
N900_RS07425	COG3706	GGDEF domain
N900_RS07455	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
N900_RS07460	COG0602	queuosine metabolic process
N900_RS07465	COG0561	phosphatase activity
N900_RS07475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N900_RS07480	COG4597	amino acid ABC transporter
N900_RS07485	COG0765	amino acid transport
N900_RS07490	COG1126	abc transporter atp-binding protein
N900_RS07495	COG0670	Belongs to the BI1 family
N900_RS07500	COG2920	part of a sulfur-relay system
N900_RS07505	COG1254	Belongs to the acylphosphatase family
N900_RS07510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N900_RS07515	COG3706	GGDEF domain
N900_RS07535	COG3437	response regulator, receiver
N900_RS07540	COG0625	glutathione transferase activity
N900_RS07550	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
N900_RS07560	COG2195	Cleaves the N-terminal amino acid of tripeptides
N900_RS07590	COG0372	Belongs to the citrate synthase family
N900_RS07595	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N900_RS07635	COG1129	ABC transporter
N900_RS07670	COG0745	RESPONSE REGULATOR receiver
N900_RS07675	COG2205	protein histidine kinase activity
N900_RS07680	COG3713	MltA-interacting MipA family protein
N900_RS07685	COG2990	Protein conserved in bacteria
N900_RS07695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N900_RS07695	COG4191	Histidine kinase
N900_RS07700	COG0471	metal ion transport
N900_RS07710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N900_RS07725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N900_RS07735	COG3768	UPF0283 membrane protein
N900_RS07740	COG3106	COG3106 Predicted ATPase
N900_RS07755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N900_RS07760	COG0494	nUDIX hydrolase
N900_RS07765	COG0814	amino acid
N900_RS07770	COG1760	l-serine dehydratase
N900_RS07775	COG0720	synthase
N900_RS07780	COG0840	transmembrane signaling receptor activity
N900_RS07785	COG0017	Asparaginyl-tRNA synthetase
N900_RS07790	COG0351	phosphomethylpyrimidine kinase
N900_RS07795	COG2770	Histidine kinase
N900_RS07795	COG3437	response regulator, receiver
N900_RS07805	COG1448	Aminotransferase
N900_RS07820	COG0840	transmembrane signaling receptor activity
N900_RS07825	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
N900_RS07830	COG2943	transferase activity, transferring hexosyl groups
N900_RS07835	COG1609	Transcriptional regulator
N900_RS07845	COG1486	melibiose metabolic process
N900_RS07850	COG1447	Phosphotransferase system cellobiose-specific component IIA
N900_RS07860	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N900_RS07865	COG0726	polysaccharide deacetylase
N900_RS07870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N900_RS07875	COG1846	Transcriptional regulator
N900_RS07900	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
N900_RS07915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N900_RS07920	COG3108	Peptidase M15
N900_RS07925	COG2989	Protein conserved in bacteria
N900_RS07950	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N900_RS07960	COG2814	Major facilitator Superfamily
N900_RS07970	COG1054	Belongs to the UPF0176 family
N900_RS07980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N900_RS07985	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N900_RS07990	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N900_RS08040	COG4139	cobalamin transport
N900_RS08060	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
N900_RS08065	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
N900_RS08070	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N900_RS08075	COG1823	symporter activity
N900_RS08080	COG2925	Exonuclease
N900_RS08085	COG1380	Effector of murein hydrolase LrgA
N900_RS08090	COG1346	cytolysis
N900_RS08130	COG0776	regulation of translation
N900_RS08135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N900_RS08135	COG0072	phenylalanine-tRNA ligase activity
N900_RS08140	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N900_RS08180	COG0322	excinuclease ABC activity
N900_RS08185	COG2197	response regulator
N900_RS08190	COG0417	DNA replication proofreading
N900_RS08195	COG5001	Diguanylate cyclase
N900_RS08205	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N900_RS08210	COG3099	Belongs to the UPF0263 family
N900_RS08225	COG1228	amidohydrolase
N900_RS08230	COG0010	Belongs to the arginase family
N900_RS08235	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
N900_RS08240	COG2986	histidine ammonia-lyase
N900_RS08260	COG0247	lactate metabolic process
N900_RS08260	COG0277	FAD linked oxidase domain protein
N900_RS08275	COG2885	chlorophyll binding
N900_RS08295	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N900_RS08305	COG0281	malic enzyme
N900_RS08315	COG2949	membrane
N900_RS08325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N900_RS08335	COG0492	ferredoxin-NADP+ reductase activity
N900_RS08340	COG4988	ABC transporter
N900_RS08345	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
N900_RS08350	COG1187	pseudouridine synthase activity
N900_RS08355	COG0009	L-threonylcarbamoyladenylate synthase
N900_RS08360	COG0613	PHP domain protein
N900_RS08370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N900_RS08375	COG0512	Glutamine amidotransferase of anthranilate synthase
N900_RS08380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N900_RS08385	COG0134	indole-3-glycerol-phosphate synthase activity
N900_RS08385	COG0135	phosphoribosylanthranilate isomerase activity
N900_RS08390	COG0133	tryptophan synthase activity
N900_RS08395	COG0159	tryptophan synthase activity
N900_RS08405	COG1435	thymidine kinase activity
N900_RS08410	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
N900_RS08415	COG1801	Protein of unknown function DUF72
N900_RS08420	COG4106	trans-aconitate 2-methyltransferase activity
N900_RS08425	COG0500	methyltransferase
N900_RS08430	COG0189	ligase activity
N900_RS08430	COG4067	protein conserved in archaea
N900_RS08445	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N900_RS08455	COG3852	Histidine kinase
N900_RS08470	COG3070	regulator of competence-specific genes
N900_RS08480	COG2431	L-lysine efflux transmembrane transporter activity
N900_RS08490	COG0076	glutamate decarboxylase activity
N900_RS08495	COG1737	Transcriptional regulator
N900_RS08500	COG1454	alcohol dehydrogenase
N900_RS08500	COG1012	belongs to the aldehyde dehydrogenase family
N900_RS08505	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N900_RS08510	COG2985	domain, Protein
N900_RS08510	COG3273	potassium ion transport
N900_RS08515	COG0542	response to heat
N900_RS08520	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N900_RS08525	COG1278	Cold shock
N900_RS08535	COG1187	pseudouridine synthase activity
N900_RS08540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N900_RS08540	COG0140	phosphoribosyl-ATP diphosphatase activity
N900_RS08545	COG0107	imidazoleglycerol-phosphate synthase activity
N900_RS08550	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N900_RS08555	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N900_RS08560	COG0131	Imidazoleglycerol-phosphate dehydratase
N900_RS08560	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
N900_RS08565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N900_RS08570	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N900_RS08575	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N900_RS08580	COG1757	Na H antiporter
N900_RS08585	COG2916	Histone family protein nucleoid-structuring protein H-NS
N900_RS08590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N900_RS08595	COG0482	sulfurtransferase activity
N900_RS08600	COG2915	High frequency lysogenization protein hflD homolog
N900_RS08605	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N900_RS08615	COG2268	Band 7 protein
N900_RS08625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
N900_RS08640	COG0300	oxidoreductase activity
N900_RS08650	COG0501	Belongs to the peptidase M48B family
N900_RS08660	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
N900_RS08665	COG2226	methyltransferase
N900_RS08670	COG0156	8-amino-7-oxononanoate synthase activity
N900_RS08675	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N900_RS08680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N900_RS08685	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N900_RS08690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N900_RS08695	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N900_RS08705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N900_RS08710	COG2203	Gaf domain
N900_RS08710	COG2199	diguanylate cyclase activity
N900_RS08720	COG4120	Belongs to the binding-protein-dependent transport system permease family
N900_RS08730	COG4628	conserved protein (DUF2132)
N900_RS08735	COG3092	negative regulation of chromosome organization
N900_RS08740	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N900_RS08745	COG0280	phosphate acetyltransferase
N900_RS08745	COG0857	belongs to the CobB CobQ family
N900_RS08750	COG0435	Glutathione S-transferase
N900_RS08755	COG4608	Belongs to the ABC transporter superfamily
N900_RS08760	COG0444	Belongs to the ABC transporter superfamily
N900_RS08765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N900_RS08770	COG0601	transmembrane transport
N900_RS08790	COG2204	response regulator
N900_RS08795	COG5001	Diguanylate cyclase
N900_RS08795	COG3300	MHYT domain
N900_RS08800	COG4191	Histidine kinase
N900_RS08805	COG5002	protein histidine kinase activity
N900_RS08815	COG2201	protein-glutamate methylesterase activity
N900_RS08830	COG0009	L-threonylcarbamoyladenylate synthase
N900_RS08850	COG1881	PFAM PEBP family protein
N900_RS08875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N900_RS08880	COG0640	Transcriptional regulator
N900_RS08885	COG3706	GGDEF domain
N900_RS08905	COG1946	Acyl-CoA thioesterase
N900_RS08910	COG1522	sequence-specific DNA binding
N900_RS08920	COG0616	signal peptide processing
N900_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
N900_RS08930	COG2983	Belongs to the UPF0260 family
N900_RS08940	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N900_RS08945	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
N900_RS08955	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N900_RS08960	COG2832	Protein of unknown function (DUF454)
N900_RS08970	COG0745	RESPONSE REGULATOR receiver
N900_RS08975	COG0583	DNA-binding transcription factor activity
N900_RS08980	COG0778	Nitroreductase
N900_RS08985	COG1024	Enoyl-CoA hydratase
N900_RS08985	COG1250	3-hydroxyacyl-CoA dehydrogenase
N900_RS08990	COG0183	Belongs to the thiolase family
N900_RS09010	COG2067	long-chain fatty acid transport protein
N900_RS09020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N900_RS09025	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
N900_RS09030	COG2982	Protein involved in outer membrane biogenesis
N900_RS09035	COG0572	uridine kinase
N900_RS09045	COG0489	protein tyrosine kinase activity
N900_RS09050	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N900_RS09050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N900_RS09060	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
N900_RS09075	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
N900_RS09075	COG0517	IMP dehydrogenase activity
N900_RS09075	COG0617	tRNA 3'-terminal CCA addition
N900_RS09080	COG2199	diguanylate cyclase activity
N900_RS09085	COG0314	molybdopterin synthase activity
N900_RS09090	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
N900_RS09095	COG0315	cyclic pyranopterin monophosphate synthase activity
N900_RS09100	COG0521	Mo-molybdopterin cofactor biosynthetic process
N900_RS09105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N900_RS09110	COG0391	Required for morphogenesis under gluconeogenic growth conditions
N900_RS09115	COG2198	Histidine kinase
N900_RS09120	COG2204	response regulator
N900_RS09130	COG0556	nucleotide-excision repair
N900_RS09140	COG4657	Part of a membrane complex involved in electron transport
N900_RS09145	COG2878	Part of a membrane complex involved in electron transport
N900_RS09170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N900_RS09175	COG0346	lactoylglutathione lyase activity
N900_RS09195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N900_RS09200	COG2056	Na+-H+ antiporter family
N900_RS09205	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N900_RS09210	COG1286	toxin biosynthetic process
N900_RS09215	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
N900_RS09220	COG0285	dihydrofolate synthase activity
N900_RS09225	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
N900_RS09230	COG0101	tRNA pseudouridine synthase activity
N900_RS09245	COG1263	PTS System
N900_RS09245	COG2190	(PTS) system
N900_RS09245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N900_RS09250	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N900_RS09255	COG1940	carbohydrate kinase activity
N900_RS09255	COG1846	Transcriptional regulator
N900_RS09260	COG4651	solute:proton antiporter activity
N900_RS09260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N900_RS09265	COG0367	asparagine synthase
N900_RS09280	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N900_RS09285	COG0563	adenylate kinase activity
N900_RS09290	COG0326	Molecular chaperone. Has ATPase activity
N900_RS09295	COG3710	Transcriptional regulator
N900_RS09310	COG0622	Phosphoesterase
N900_RS09315	COG1090	epimerase
N900_RS09320	COG0300	oxidoreductase activity
N900_RS09325	COG3118	belongs to the thioredoxin family
N900_RS09330	COG0330	HflC and HflK could
N900_RS09335	COG1585	Membrane protein implicated in regulation of membrane protease activity
N900_RS09340	COG0789	Transcriptional regulator
N900_RS09355	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N900_RS09360	COG3115	cell septum assembly
N900_RS09365	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
N900_RS09370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N900_RS09380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N900_RS09390	COG2190	(PTS) system
N900_RS09395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N900_RS09400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N900_RS09405	COG1702	phosphate starvation-inducible protein PhoH
N900_RS09415	COG4535	Mg2 and Co2 transporter CorC
N900_RS09420	COG0815	Transfers the fatty acyl group on membrane lipoproteins
N900_RS09425	COG2888	peptidyl-tyrosine sulfation
N900_RS09430	COG0495	leucyl-tRNA aminoacylation
N900_RS09435	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
N900_RS09440	COG1466	dna polymerase III delta subunit
N900_RS09445	COG0799	negative regulation of ribosome biogenesis
N900_RS09450	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
N900_RS09455	COG0768	penicillin binding
N900_RS09460	COG0772	Belongs to the SEDS family
N900_RS09465	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N900_RS09470	COG1686	Belongs to the peptidase S11 family
N900_RS09480	COG2921	Belongs to the UPF0250 family
N900_RS09485	COG0321	lipoyl(octanoyl) transferase activity
N900_RS09490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N900_RS09500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N900_RS09525	COG1596	polysaccharide export
N900_RS09535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N900_RS09565	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
N900_RS09575	COG0438	transferase activity, transferring glycosyl groups
N900_RS09585	COG1045	serine acetyltransferase
N900_RS09605	COG0110	maltose O-acetyltransferase activity
N900_RS09610	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
N900_RS09615	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
N900_RS09620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N900_RS09625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N900_RS09650	COG0366	Alpha amylase catalytic
N900_RS09655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N900_RS09655	COG1263	PTS System
N900_RS09660	COG1609	Transcriptional regulator
N900_RS09665	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
N900_RS09670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N900_RS09675	COG2011	ABC-type metal ion transport system permease component
N900_RS09680	COG1464	Belongs to the NlpA lipoprotein family
N900_RS09685	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
N900_RS09695	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N900_RS09695	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N900_RS09710	COG1611	Belongs to the LOG family
N900_RS09715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N900_RS09720	COG2363	Small membrane protein
N900_RS09725	COG0583	DNA-binding transcription factor activity
N900_RS09735	COG0301	tRNA thio-modification
N900_RS09735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N900_RS09745	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N900_RS09750	COG1722	exodeoxyribonuclease VII activity
N900_RS09755	COG0142	geranyltranstransferase activity
N900_RS09760	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N900_RS09765	COG0564	pseudouridine synthase activity
N900_RS09770	COG3098	single-species biofilm formation
N900_RS09785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N900_RS09795	COG1671	Belongs to the UPF0178 family
N900_RS09800	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
N900_RS09805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N900_RS09810	COG0254	rRNA binding
N900_RS09815	COG1720	tRNA m6t6A37 methyltransferase activity
N900_RS09820	COG0442	prolyl-tRNA aminoacylation
N900_RS09850	COG0047	phosphoribosylformylglycinamidine synthase activity
N900_RS09850	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N900_RS09860	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
N900_RS09875	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
N900_RS09910	COG0484	heat shock protein binding
N900_RS09915	COG0443	Heat shock 70 kDa protein
N900_RS09920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N900_RS09925	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N900_RS09930	COG0497	DNA recombination
N900_RS09935	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N900_RS09940	COG2914	Belongs to the UPF0125 (RnfH) family
N900_RS09945	COG2867	negative regulation of translational initiation
N900_RS09950	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N900_RS09955	COG0582	viral genome integration into host DNA
N900_RS09965	COG3064	Membrane
N900_RS09975	COG0739	heme binding
N900_RS10010	COG1459	type II secretion system
N900_RS10015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N900_RS10035	COG4796	Type ii and iii secretion system protein
N900_RS10050	COG2165	general secretion pathway protein
N900_RS10060	COG3710	Transcriptional regulator
N900_RS10065	COG0840	transmembrane signaling receptor activity
N900_RS10070	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
N900_RS10090	COG1012	belongs to the aldehyde dehydrogenase family
N900_RS10160	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
N900_RS10165	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
N900_RS10170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N900_RS10190	COG3051	citrate lyase alpha subunit
N900_RS10195	COG2301	Belongs to the HpcH HpaI aldolase family
N900_RS10205	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
N900_RS10215	COG3630	sodium ion export across plasma membrane
N900_RS10220	COG0511	ligase activity, forming carbon-carbon bonds
N900_RS10220	COG5016	pyruvate
N900_RS10225	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
N900_RS10235	COG4565	transcriptional regulatory protein
N900_RS10250	COG0583	DNA-binding transcription factor activity
N900_RS10260	COG1115	amino acid carrier protein
N900_RS10265	COG2015	COG2015, Alkyl sulfatase and related hydrolases
N900_RS10270	COG0583	DNA-binding transcription factor activity
N900_RS10280	COG1120	ATPase activity
N900_RS10285	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N900_RS10290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N900_RS10295	COG4592	Periplasmic binding protein
N900_RS10305	COG1028	Short-chain dehydrogenase reductase Sdr
N900_RS10310	COG1169	isochorismate synthase
N900_RS10315	COG1021	2,3-dihydroxybenzoate-AMP ligase
N900_RS10320	COG1535	isochorismatase
N900_RS10320	COG3433	isochorismatase activity
N900_RS10325	COG1584	GPR1 FUN34 yaaH family protein
N900_RS10335	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N900_RS10335	COG0519	Catalyzes the synthesis of GMP from XMP
N900_RS10340	COG0517	IMP dehydrogenase activity
N900_RS10340	COG0516	GMP reductase activity
N900_RS10345	COG1570	exodeoxyribonuclease VII activity
N900_RS10360	COG1160	GTP binding
N900_RS10365	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N900_RS10370	COG2976	Protein conserved in bacteria
N900_RS10375	COG0124	histidyl-tRNA synthetase
N900_RS10380	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N900_RS10390	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N900_RS10395	COG0105	UTP biosynthetic process
N900_RS10400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N900_RS10405	COG2975	iron-sulfur cluster assembly
N900_RS10410	COG0633	Ferredoxin
N900_RS10415	COG0443	Heat shock 70 kDa protein
N900_RS10420	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
N900_RS10430	COG0822	iron-sulfur transferase activity
N900_RS10435	COG1104	cysteine desulfurase activity
N900_RS10440	COG1959	2 iron, 2 sulfur cluster binding
N900_RS10450	COG0483	inositol monophosphate 1-phosphatase activity
N900_RS10455	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N900_RS10460	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N900_RS10465	COG1862	Preprotein translocase
N900_RS10485	COG0517	IMP dehydrogenase activity
N900_RS10495	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N900_RS10500	COG0583	DNA-binding transcription factor activity
N900_RS10505	COG0450	alkyl hydroperoxide reductase
N900_RS10510	COG3142	Participates in the control of copper homeostasis
N900_RS10525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N900_RS10530	COG0581	inorganic phosphate transmembrane transporter activity
N900_RS10540	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
N900_RS10545	COG0248	Ppx GppA phosphatase
N900_RS10555	COG5002	protein histidine kinase activity
N900_RS10560	COG0745	RESPONSE REGULATOR receiver
N900_RS10570	COG0826	peptidase U32
N900_RS10575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N900_RS10615	COG0542	response to heat
N900_RS10625	COG0564	pseudouridine synthase activity
N900_RS10630	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N900_RS10635	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N900_RS10640	COG1605	Chorismate mutase
N900_RS10640	COG0077	Prephenate dehydratase
N900_RS10645	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
N900_RS10650	COG5001	Diguanylate cyclase
N900_RS10660	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
N900_RS10670	COG0488	(ABC) transporter
N900_RS10680	COG1605	Chorismate mutase
N900_RS10680	COG0287	Prephenate dehydrogenase
N900_RS10685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N900_RS10690	COG3275	phosphorelay sensor kinase activity
N900_RS10695	COG3279	Response regulator of the LytR AlgR family
N900_RS10705	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
N900_RS10710	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N900_RS10725	COG1966	Carbon starvation protein
N900_RS10730	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
N900_RS10735	COG1047	Peptidyl-prolyl cis-trans
N900_RS10750	COG0196	riboflavin kinase activity
N900_RS10755	COG0728	peptidoglycan biosynthetic process
N900_RS10760	COG0268	Binds directly to 16S ribosomal RNA
N900_RS10765	COG0640	Transcriptional regulator
N900_RS10770	COG0583	DNA-binding transcription factor activity
N900_RS10775	COG1283	sodium-dependent phosphate transmembrane transporter activity
N900_RS10785	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
N900_RS10790	COG0730	response to heat
N900_RS10795	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
N900_RS10800	COG0494	nUDIX hydrolase
N900_RS10815	COG0667	Aldo Keto reductase
N900_RS10825	COG2204	response regulator
N900_RS10830	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N900_RS10835	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
N900_RS10850	COG0513	Belongs to the DEAD box helicase family
N900_RS10965	COG2003	Belongs to the UPF0758 family
N900_RS10990	COG0714	Associated with various cellular activities
N900_RS11005	COG0629	single-stranded DNA binding
N900_RS11020	COG2356	endonuclease I
N900_RS11060	COG0681	Belongs to the peptidase S26 family
N900_RS11075	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N900_RS11210	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N900_RS11225	COG3328	transposase activity
N900_RS11230	COG3328	transposase activity
N900_RS11345	COG3153	acetyltransferase
N900_RS11350	COG3154	lipid carrier protein
N900_RS11360	COG0826	peptidase U32
N900_RS11365	COG0826	peptidase U32
N900_RS11390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N900_RS11400	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N900_RS11405	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
N900_RS11410	COG0195	Participates in both transcription termination and antitermination
N900_RS11415	COG0779	Required for maturation of 30S ribosomal subunits
N900_RS11430	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N900_RS11445	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N900_RS11450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N900_RS11455	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
N900_RS11460	COG1534	Rna-binding protein
N900_RS11465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N900_RS11470	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
N900_RS11475	COG2027	D-alanyl-D-alanine carboxypeptidase
N900_RS11480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N900_RS11485	COG0739	heme binding
N900_RS11500	COG0316	Belongs to the HesB IscA family
N900_RS11510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N900_RS11520	COG0628	permease
N900_RS11525	COG2813	Specifically methylates the guanine in position
N900_RS11530	COG2205	protein histidine kinase activity
N900_RS11530	COG0784	Response regulator, receiver
N900_RS11540	COG0747	negative chemotaxis
N900_RS11545	COG0601	transmembrane transport
N900_RS11550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N900_RS11555	COG0444	Belongs to the ABC transporter superfamily
N900_RS11560	COG4608	Belongs to the ABC transporter superfamily
N900_RS11570	COG2971	BadF BadG BcrA BcrD
N900_RS11590	COG3842	ATPase activity
N900_RS11600	COG1840	ABC-type Fe3 transport system, periplasmic component
N900_RS11605	COG0004	ammonium transporteR
N900_RS11610	COG0347	Belongs to the P(II) protein family
N900_RS11615	COG3112	Uncharacterised protein family (UPF0231)
N900_RS11620	COG1049	propionate catabolic process, 2-methylcitrate cycle
N900_RS11625	COG1752	Esterase of the alpha-beta hydrolase superfamily
N900_RS11630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N900_RS11635	COG1643	Atp-dependent helicase
N900_RS11645	COG1489	DNA binding
N900_RS11655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N900_RS11665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N900_RS11670	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N900_RS11675	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N900_RS11680	COG0842	Transport permease protein
N900_RS11685	COG1131	(ABC) transporter
N900_RS11690	COG0659	secondary active sulfate transmembrane transporter activity
N900_RS11695	COG0288	reversible hydration of carbon dioxide
N900_RS11710	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
N900_RS11715	COG3107	peptidoglycan biosynthetic process
N900_RS11720	COG0792	nuclease activity
N900_RS11725	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
N900_RS11730	COG2823	Periplasmic or secreted lipoprotein
N900_RS11735	COG2969	positive regulation of protein catabolic process
N900_RS11740	COG0625	glutathione transferase activity
N900_RS11745	COG2857	Cytochrome c1
N900_RS11750	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N900_RS11755	COG0723	plastoquinol--plastocyanin reductase activity
N900_RS11760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N900_RS11765	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N900_RS11775	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
N900_RS11785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N900_RS11790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N900_RS11795	COG0335	large ribosomal subunit rRNA binding
N900_RS11800	COG0336	Belongs to the RNA methyltransferase TrmD family
N900_RS11805	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N900_RS11810	COG0228	four-way junction DNA binding
N900_RS11815	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N900_RS11820	COG4137	Cytochrome C assembly protein
N900_RS11825	COG4536	flavin adenine dinucleotide binding
N900_RS11830	COG1854	S-ribosylhomocysteine lyase activity
N900_RS11835	COG2918	glutathione biosynthetic process
N900_RS11840	COG0612	Peptidase, M16
N900_RS11845	COG1238	metal cluster binding
N900_RS11855	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
N900_RS11860	COG5016	pyruvate
N900_RS11860	COG0511	ligase activity, forming carbon-carbon bonds
N900_RS11865	COG3630	sodium ion export across plasma membrane
N900_RS11915	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
N900_RS11920	COG0527	aspartate kinase activity
N900_RS11925	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N900_RS11935	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N900_RS11945	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N900_RS11950	COG4208	sulfate ABC transporter
N900_RS11970	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
N900_RS11975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N900_RS11985	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N900_RS11990	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
N900_RS11995	COG0585	pseudouridine synthase activity
N900_RS12000	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N900_RS12005	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N900_RS12010	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N900_RS12015	COG1968	undecaprenyl-diphosphatase activity
N900_RS12020	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N900_RS12025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N900_RS12030	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N900_RS12040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
N900_RS12045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
N900_RS12050	COG1610	YqeY-like protein
N900_RS12055	COG0358	DNA primase activity
N900_RS12070	COG0582	viral genome integration into host DNA
N900_RS12075	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N900_RS12085	COG2207	Transcriptional regulator
N900_RS12130	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
N900_RS12135	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N900_RS12140	COG1349	DNA-binding transcription factor activity
N900_RS12160	COG1279	arginine transmembrane transporter activity
N900_RS12165	COG0668	transmembrane transport
N900_RS12175	COG0191	fructose-bisphosphate aldolase activity
N900_RS12180	COG0126	phosphoglycerate kinase activity
N900_RS12185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N900_RS12190	COG4771	TonB-dependent receptor
N900_RS12195	COG0583	DNA-binding transcription factor activity
N900_RS12210	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N900_RS12220	COG2356	endonuclease I
N900_RS12225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N900_RS12230	COG0189	ligase activity
N900_RS12235	COG1678	Uncharacterized ACR, COG1678
N900_RS12240	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N900_RS12245	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N900_RS12265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N900_RS12270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N900_RS12275	COG0762	integral membrane protein
N900_RS12280	COG1872	DUF167
N900_RS12290	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N900_RS12295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N900_RS12300	COG2066	Belongs to the glutaminase family
N900_RS12310	COG1194	a g-specific adenine glycosylase
N900_RS12315	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
N900_RS12320	COG0741	lytic transglycosylase activity
N900_RS12345	COG0840	transmembrane signaling receptor activity
N900_RS12365	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
N900_RS12370	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
N900_RS12375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N900_RS12380	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
N900_RS12385	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N900_RS12390	COG2967	ApaG domain
N900_RS12395	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N900_RS12405	COG3610	response to peptide
N900_RS12410	COG2966	Psort location CytoplasmicMembrane, score
N900_RS12415	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N900_RS12420	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N900_RS12425	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N900_RS12430	COG0142	geranyltranstransferase activity
N900_RS12435	COG0531	amino acid
N900_RS12440	COG0531	amino acid
N900_RS12445	COG0039	L-malate dehydrogenase activity
N900_RS12450	COG1438	arginine binding
N900_RS12455	COG2358	TRAP transporter, solute receptor (TAXI family
N900_RS12465	COG0589	response to stress
N900_RS12485	COG2235	arginine
N900_RS12490	COG0312	modulator of DNA gyrase
N900_RS12495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N900_RS12500	COG3164	Protein of unknown function
N900_RS12510	COG0424	maF-like protein
N900_RS12515	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N900_RS12520	COG1792	Involved in formation and maintenance of cell shape
N900_RS12525	COG1077	Cell shape determining protein MreB Mrl
N900_RS12555	COG2165	general secretion pathway protein
N900_RS12560	COG2165	general secretion pathway protein
N900_RS12570	COG1459	type II secretion system
N900_RS12575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N900_RS12585	COG3267	Type II secretory pathway component ExeA
N900_RS12585	COG3409	Peptidoglycan-binding domain 1 protein
N900_RS12610	COG2200	EAL domain
N900_RS12610	COG2199	diguanylate cyclase activity
N900_RS12615	COG0629	single-stranded DNA binding
N900_RS12630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N900_RS12640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N900_RS12645	COG0527	aspartate kinase activity
N900_RS12650	COG0646	methionine synthase
N900_RS12650	COG1410	methionine synthase
N900_RS12690	COG0175	sulfate reduction
N900_RS12700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N900_RS12725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N900_RS12730	COG0735	belongs to the Fur family
N900_RS12750	COG0432	Pfam Uncharacterised protein family UPF0047
N900_RS12755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N900_RS12770	COG0359	binds to the 23S rRNA
N900_RS12775	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
N900_RS12780	COG2965	DNA replication, synthesis of RNA primer
N900_RS12785	COG0360	Binds together with S18 to 16S ribosomal RNA
N900_RS12795	COG2906	2 iron, 2 sulfur cluster binding
N900_RS12800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N900_RS12805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N900_RS12810	COG0049	tRNA binding
N900_RS12825	COG2923	Belongs to the DsrF TusC family
N900_RS12830	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
N900_RS12835	COG2964	Protein conserved in bacteria
N900_RS12840	COG0545	Peptidyl-prolyl cis-trans isomerase
N900_RS12850	COG2900	Belongs to the SlyX family
N900_RS12855	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
N900_RS12860	COG0330	HflC and HflK could
N900_RS12865	COG0330	HflC and HflK could
N900_RS12870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N900_RS12875	COG1923	regulation of RNA biosynthetic process
N900_RS12880	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N900_RS12885	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N900_RS12895	COG0802	atpase or kinase
N900_RS12900	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N900_RS12945	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
N900_RS12950	COG1162	GTPase activity
N900_RS12955	COG0688	phosphatidylethanolamine metabolic process
N900_RS12960	COG0471	metal ion transport
N900_RS12970	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N900_RS12975	COG4942	peptidase
N900_RS12990	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N900_RS12995	COG2816	NAD+ diphosphatase activity
N900_RS13000	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
N900_RS13005	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N900_RS13010	COG0085	RNA polymerase activity
N900_RS13015	COG0222	ribosome binding
N900_RS13020	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N900_RS13030	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
N900_RS13035	COG0250	Participates in transcription elongation, termination and antitermination
N900_RS13040	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N900_RS13045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N900_RS13070	COG1072	(Pantothenic acid kinase))
N900_RS13080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N900_RS13095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N900_RS13140	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
N900_RS13155	COG3118	belongs to the thioredoxin family
N900_RS13160	COG0513	Belongs to the DEAD box helicase family
N900_RS13165	COG0248	Ppx GppA phosphatase
N900_RS13170	COG0784	Response regulator, receiver
N900_RS13170	COG2205	protein histidine kinase activity
N900_RS13175	COG2814	Major facilitator Superfamily
N900_RS13195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N900_RS13200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N900_RS13205	COG0511	ligase activity, forming carbon-carbon bonds
N900_RS13210	COG0439	Biotin carboxylase
N900_RS13215	COG2264	protein methyltransferase activity
N900_RS13220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N900_RS13225	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
N900_RS13230	COG1609	Transcriptional regulator
N900_RS13235	COG0129	dihydroxy-acid dehydratase activity
N900_RS13240	COG3265	gluconokinase activity
N900_RS13250	COG0800	Aldolase
N900_RS13270	COG0840	transmembrane signaling receptor activity
N900_RS13275	COG1982	Orn Lys Arg decarboxylase major
N900_RS13280	COG0531	amino acid
N900_RS13285	COG3710	Transcriptional regulator
N900_RS13290	COG0789	Transcriptional regulator
N900_RS13305	COG0151	Belongs to the GarS family
N900_RS13315	COG0776	regulation of translation
N900_RS13325	COG1253	flavin adenine dinucleotide binding
N900_RS13330	COG1940	carbohydrate kinase activity
N900_RS13340	COG3068	Protein conserved in bacteria
N900_RS13350	COG1573	uracil-dna glycosylase
N900_RS13355	COG0668	transmembrane transport
N900_RS13360	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
N900_RS13365	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N900_RS13395	COG5433	transposase activity
N900_RS13410	COG1012	belongs to the aldehyde dehydrogenase family
N900_RS13410	COG1454	alcohol dehydrogenase
N900_RS13415	COG0318	PFAM AMP-dependent synthetase and ligase
N900_RS13445	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
N900_RS13450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N900_RS13455	COG0662	Cupin 2, conserved barrel domain protein
N900_RS13455	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
N900_RS13460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N900_RS13495	COG1519	Transferase
N900_RS13525	COG3642	lipopolysaccharide core region biosynthetic process
N900_RS13530	COG0859	PFAM glycosyl transferase family 9
N900_RS13535	COG0463	Glycosyl transferase, family 2
N900_RS13540	COG0859	PFAM glycosyl transferase family 9
N900_RS13545	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N900_RS13550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N900_RS13560	COG0267	Belongs to the bacterial ribosomal protein bL33 family
N900_RS13565	COG0227	Belongs to the bacterial ribosomal protein bL28 family
N900_RS13570	COG2003	Belongs to the UPF0758 family
N900_RS13580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N900_RS13585	COG1309	transcriptional regulator
N900_RS13590	COG1560	Kdo2-lipid A biosynthetic process
N900_RS13595	COG1560	Kdo2-lipid A biosynthetic process
N900_RS13600	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N900_RS13605	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N900_RS13610	COG1561	YicC-like family, N-terminal region
N900_RS13615	COG2862	Uncharacterized protein family, UPF0114
N900_RS13620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N900_RS13620	COG1263	PTS System
N900_RS13625	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N900_RS13650	COG1120	ATPase activity
N900_RS13655	COG4774	siderophore transport
N900_RS13660	COG1132	(ABC) transporter
N900_RS13675	COG0514	ATP-dependent DNA helicase (RecQ)
N900_RS13680	COG2962	Rard protein
N900_RS13695	COG1280	lysine exporter protein (LysE YggA)
N900_RS13700	COG0210	DNA helicase
N900_RS13710	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
N900_RS13715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N900_RS13755	COG3621	Patatin-like phospholipase
N900_RS13780	COG2131	deaminase
N900_RS13790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N900_RS13795	COG0601	transmembrane transport
N900_RS13800	COG0747	negative chemotaxis
N900_RS13855	COG1309	transcriptional regulator
N900_RS13860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N900_RS13865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N900_RS13870	COG2960	long-chain fatty acid transporting porin activity
N900_RS13875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N900_RS13880	COG0583	DNA-binding transcription factor activity
N900_RS13925	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
N900_RS13930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N900_RS13935	COG1739	Uncharacterized protein family UPF0029
N900_RS13945	COG0183	Belongs to the thiolase family
N900_RS13950	COG0583	DNA-binding transcription factor activity
N900_RS13955	COG2814	Major facilitator Superfamily
N900_RS13960	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N900_RS13965	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N900_RS13970	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N900_RS13975	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N900_RS13980	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
N900_RS13985	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N900_RS13990	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N900_RS14000	COG0356	it plays a direct role in the translocation of protons across the membrane
N900_RS14005	COG3312	ion transport
N900_RS14010	COG1475	DNA binding
N900_RS14015	COG1192	Involved in chromosome partitioning
N900_RS14025	COG0445	tRNA wobble uridine modification
N900_RS14040	COG0706	membrane insertase activity
N900_RS14070	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
N900_RS14175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N900_RS14230	COG0408	coproporphyrinogen oxidase activity
N900_RS14460	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N900_RS14460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N900_RS14550	COG2200	EAL domain
N900_RS14550	COG3287	FIST C domain
N900_RS14550	COG2199	diguanylate cyclase activity
N900_RS14590	COG0552	protein localization to endoplasmic reticulum
N900_RS14785	COG1459	type II secretion system
N900_RS14880	COG0194	GDP metabolic process
N900_RS14890	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N900_RS14925	COG4232	protein-disulfide reductase activity
N900_RS15160	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
N900_RS15210	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
N900_RS15415	COG0557	exoribonuclease II activity
N900_RS15530	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
N900_RS15535	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N900_RS15580	COG0513	Belongs to the DEAD box helicase family
N900_RS15640	COG0529	Catalyzes the synthesis of activated sulfate
N900_RS15910	COG2854	intermembrane phospholipid transfer
N900_RS15960	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N900_RS16185	COG1022	Amp-dependent synthetase and ligase
N900_RS16230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N900_RS16455	COG1459	type II secretion system
N900_RS16490	COG0737	Belongs to the 5'-nucleotidase family
N900_RS16530	COG0508	dehydrogenase complex catalyzes the overall conversion of
N900_RS16635	COG0653	protein targeting
N900_RS16640	COG0653	protein targeting
N900_RS16665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N900_RS16720	COG0069	glutamate synthase activity
N900_RS16720	COG0067	glutamate synthase
N900_RS16720	COG0070	glutamate synthase
N900_RS16725	COG0067	glutamate synthase
N900_RS16725	COG0069	glutamate synthase activity
N900_RS16725	COG0070	glutamate synthase
N900_RS16785	COG1242	4 iron, 4 sulfur cluster binding
N900_RS16935	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N900_RS16975	COG3250	beta-galactosidase activity
N900_RS17145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N900_RS17185	COG2195	Cleaves the N-terminal amino acid of tripeptides
N900_RS17205	COG1073	alpha beta
N900_RS17255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N900_RS17380	COG0587	DNA-directed DNA polymerase activity
N900_RS17540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N900_RS17700	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
N900_RS17955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N900_RS17990	COG0033	Phosphoglucomutase
N900_RS18175	COG0643	Histidine kinase
N900_RS18175	COG0784	Response regulator, receiver
N900_RS18175	COG2198	Histidine kinase
N900_RS18680	COG2951	lytic endotransglycosylase activity
N900_RS18920	COG1674	ftsk spoiiie
N900_RS18925	COG1674	ftsk spoiiie
N900_RS18950	COG0840	transmembrane signaling receptor activity
N900_RS18955	COG0840	transmembrane signaling receptor activity