locus-tag	class	description
KTC41_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KTC41_RS00010	COG0592	DNA-directed DNA polymerase activity
KTC41_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KTC41_RS00020	COG0187	DNA topoisomerase II activity
KTC41_RS00025	COG3977	Valine--pyruvate aminotransferase
KTC41_RS00030	COG0751	glycine-tRNA ligase activity
KTC41_RS00035	COG0752	glycyl-tRNA synthetase alpha subunit
KTC41_RS00040	COG2119	membrane
KTC41_RS00050	COG0425	Belongs to the sulfur carrier protein TusA family
KTC41_RS00060	COG0604	alcohol dehydrogenase
KTC41_RS00070	COG0129	dihydroxy-acid dehydratase activity
KTC41_RS00075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KTC41_RS00090	COG0606	chelatase, subunit chli
KTC41_RS00095	COG0204	Acyl-transferase
KTC41_RS00100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KTC41_RS00105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KTC41_RS00115	COG3084	Protein conserved in bacteria
KTC41_RS00120	COG4326	sporulation control protein
KTC41_RS00125	COG1272	protein, Hemolysin III
KTC41_RS00135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KTC41_RS00140	COG0569	domain protein
KTC41_RS00145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KTC41_RS00145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KTC41_RS00150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KTC41_RS00155	COG0242	peptide deformylase activity
KTC41_RS00160	COG1652	LysM domain
KTC41_RS00165	COG0758	DNA mediated transformation
KTC41_RS00170	COG2922	Belongs to the Smg family
KTC41_RS00175	COG0551	DNA topoisomerase type I activity
KTC41_RS00180	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KTC41_RS00185	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KTC41_RS00190	COG0009	L-threonylcarbamoyladenylate synthase
KTC41_RS00195	COG0408	coproporphyrinogen oxidase activity
KTC41_RS00200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KTC41_RS00210	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KTC41_RS00250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KTC41_RS00255	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KTC41_RS00265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KTC41_RS00270	COG2104	thiamine diphosphate biosynthetic process
KTC41_RS00275	COG2022	thiamine diphosphate biosynthetic process
KTC41_RS00280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KTC41_RS00285	COG0006	proline dipeptidase activity
KTC41_RS00285	COG0006	proline dipeptidase activity
KTC41_RS00305	COG1522	sequence-specific DNA binding
KTC41_RS00310	COG5002	protein histidine kinase activity
KTC41_RS00310	COG5001	Diguanylate cyclase
KTC41_RS00330	COG0589	response to stress
KTC41_RS00335	COG1528	Iron-storage protein
KTC41_RS00345	COG2081	HI0933 family
KTC41_RS00355	COG1322	Protein conserved in bacteria
KTC41_RS00360	COG2226	methyltransferase
KTC41_RS00375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KTC41_RS00380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KTC41_RS00385	COG0805	protein transport
KTC41_RS00390	COG0534	Mate efflux family protein
KTC41_RS00400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KTC41_RS00405	COG2937	Belongs to the GPAT DAPAT family
KTC41_RS00410	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KTC41_RS00415	COG3161	chorismate lyase activity
KTC41_RS00420	COG1580	Controls the rotational direction of flagella during chemotaxis
KTC41_RS00425	COG0840	transmembrane signaling receptor activity
KTC41_RS00435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KTC41_RS00440	COG0084	hydrolase, TatD family'
KTC41_RS00455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KTC41_RS00455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KTC41_RS00475	COG3078	GTPase activator activity
KTC41_RS00490	COG3071	HemY protein
KTC41_RS00495	COG2959	enzyme of heme biosynthesis
KTC41_RS00500	COG1587	Uroporphyrinogen-III synthase
KTC41_RS00505	COG0181	hydroxymethylbilane synthase activity
KTC41_RS00515	COG1965	Belongs to the frataxin family
KTC41_RS00525	COG0019	diaminopimelate decarboxylase activity
KTC41_RS00530	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KTC41_RS00540	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KTC41_RS00545	COG1011	Hydrolase
KTC41_RS00550	COG2199	diguanylate cyclase activity
KTC41_RS00550	COG2200	EAL domain
KTC41_RS00550	COG3287	FIST C domain
KTC41_RS00565	COG0561	phosphatase activity
KTC41_RS00570	COG2267	carboxylic ester hydrolase activity
KTC41_RS00575	COG1280	lysine exporter protein (LysE YggA)
KTC41_RS00580	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KTC41_RS00585	COG0783	Belongs to the Dps family
KTC41_RS00610	COG0742	ribosomal rna small subunit methyltransferase
KTC41_RS00615	COG0552	protein localization to endoplasmic reticulum
KTC41_RS00620	COG2884	Cell division ATP-binding protein ftsE
KTC41_RS00625	COG2177	Part of the ABC transporter FtsEX involved in
KTC41_RS00630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KTC41_RS00635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KTC41_RS00650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KTC41_RS00665	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KTC41_RS00735	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KTC41_RS00740	COG5001	Diguanylate cyclase
KTC41_RS00740	COG3300	MHYT domain
KTC41_RS00750	COG3852	Histidine kinase
KTC41_RS00760	COG0174	glutamine synthetase
KTC41_RS00770	COG1217	gtp-binding protein TYPA
KTC41_RS00780	COG1295	ribonuclease BN
KTC41_RS00785	COG1490	D-aminoacyl-tRNA deacylase activity
KTC41_RS00790	COG0456	acetyltransferase
KTC41_RS00800	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KTC41_RS00805	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KTC41_RS00810	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KTC41_RS00815	COG3031	protein transport across the cell outer membrane
KTC41_RS00825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KTC41_RS00830	COG1459	type II secretion system
KTC41_RS00835	COG2165	general secretion pathway protein
KTC41_RS00840	COG2165	general secretion pathway protein
KTC41_RS00845	COG2165	general secretion pathway protein
KTC41_RS00850	COG4795	General secretion pathway protein
KTC41_RS00855	COG3156	type II secretion system protein K
KTC41_RS00860	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KTC41_RS00865	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KTC41_RS00875	COG1218	3'(2'),5'-bisphosphate nucleotidase
KTC41_RS00880	COG0494	nUDIX hydrolase
KTC41_RS00890	COG1040	competence protein
KTC41_RS00900	COG0596	Alpha beta hydrolase
KTC41_RS00910	COG2183	response to ionizing radiation
KTC41_RS00915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KTC41_RS00920	COG2199	diguanylate cyclase activity
KTC41_RS00935	COG2233	PERMEase
KTC41_RS00940	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KTC41_RS00945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KTC41_RS00950	COG1758	RNA polymerase activity
KTC41_RS00955	COG0194	GDP metabolic process
KTC41_RS00960	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KTC41_RS00965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KTC41_RS00985	COG4232	protein-disulfide reductase activity
KTC41_RS00990	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KTC41_RS00995	COG1027	Aspartate ammonia-lyase
KTC41_RS01000	COG3030	protein affecting phage T7 exclusion by the F plasmid
KTC41_RS01005	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KTC41_RS01015	COG2205	protein histidine kinase activity
KTC41_RS01020	COG0745	RESPONSE REGULATOR receiver
KTC41_RS01030	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KTC41_RS01035	COG0205	6-phosphofructokinase activity
KTC41_RS01040	COG1494	fructose-1,6-bisphosphatase
KTC41_RS01045	COG3074	FtsZ-dependent cytokinesis
KTC41_RS01050	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KTC41_RS01055	COG0527	aspartate kinase activity
KTC41_RS01055	COG0460	homoserine dehydrogenase
KTC41_RS01060	COG0626	cystathionine gamma-synthase activity
KTC41_RS01065	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
KTC41_RS01070	COG0281	malic enzyme
KTC41_RS01075	COG0254	rRNA binding
KTC41_RS01080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KTC41_RS01085	COG1609	Transcriptional regulator
KTC41_RS01090	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KTC41_RS01095	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KTC41_RS01100	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KTC41_RS01105	COG1575	Belongs to the MenA family. Type 1 subfamily
KTC41_RS01110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KTC41_RS01115	COG0534	Mate efflux family protein
KTC41_RS01120	COG0149	triose-phosphate isomerase activity
KTC41_RS01145	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KTC41_RS01150	COG0459	protein refolding
KTC41_RS01160	COG1509	lysine 2,3-aminomutase activity
KTC41_RS01165	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KTC41_RS01175	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KTC41_RS01180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KTC41_RS01185	COG1053	succinate dehydrogenase
KTC41_RS01190	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KTC41_RS01195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KTC41_RS01200	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KTC41_RS01205	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KTC41_RS01210	COG1045	serine acetyltransferase
KTC41_RS01220	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KTC41_RS01225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KTC41_RS01230	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KTC41_RS01235	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KTC41_RS01240	COG0137	argininosuccinate synthase activity
KTC41_RS01245	COG0165	Argininosuccinate lyase
KTC41_RS01255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KTC41_RS01260	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KTC41_RS01260	COG0678	peroxiredoxin activity
KTC41_RS01270	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KTC41_RS01300	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KTC41_RS01305	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KTC41_RS01315	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KTC41_RS01320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KTC41_RS01325	COG0546	phosphoglycolate phosphatase activity
KTC41_RS01330	COG0180	Tryptophanyl-tRNA synthetase
KTC41_RS01355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KTC41_RS01365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KTC41_RS01385	COG3385	transposase activity
KTC41_RS01395	COG3954	Phosphoribulokinase
KTC41_RS01405	COG0429	hydrolase of the alpha beta-hydrolase fold
KTC41_RS01415	COG0488	(ABC) transporter
KTC41_RS01425	COG1047	Peptidyl-prolyl cis-trans
KTC41_RS01435	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KTC41_RS01440	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KTC41_RS01445	COG3083	sulfuric ester hydrolase activity
KTC41_RS01450	COG0557	exoribonuclease II activity
KTC41_RS01455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KTC41_RS01460	COG0051	transcription antitermination factor activity, RNA binding
KTC41_RS01465	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KTC41_RS01470	COG0088	Forms part of the polypeptide exit tunnel
KTC41_RS01475	COG0089	rRNA binding
KTC41_RS01480	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KTC41_RS01485	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KTC41_RS01490	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KTC41_RS01495	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KTC41_RS01500	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KTC41_RS01505	COG0255	Belongs to the universal ribosomal protein uL29 family
KTC41_RS01510	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KTC41_RS01515	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KTC41_RS01520	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KTC41_RS01525	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KTC41_RS01530	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KTC41_RS01535	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KTC41_RS01540	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KTC41_RS01545	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KTC41_RS01550	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KTC41_RS01555	COG1841	ribosomal large subunit assembly
KTC41_RS01565	COG0201	protein transport
KTC41_RS01570	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KTC41_RS01575	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KTC41_RS01580	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KTC41_RS01585	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KTC41_RS01590	COG0202	RNA polymerase activity
KTC41_RS01595	COG0203	ribosomal protein L17
KTC41_RS01605	COG0545	Peptidyl-prolyl cis-trans isomerase
KTC41_RS01610	COG3061	Opacity-associated protein A
KTC41_RS01610	COG3266	domain, Protein
KTC41_RS01615	COG0697	spore germination
KTC41_RS01620	COG2153	protein acetylation
KTC41_RS01625	COG0513	Belongs to the DEAD box helicase family
KTC41_RS01640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KTC41_RS01640	COG1648	precorrin-2 dehydrogenase activity
KTC41_RS01650	COG2895	sulfate adenylyltransferase (ATP) activity
KTC41_RS01655	COG0529	Catalyzes the synthesis of activated sulfate
KTC41_RS01675	COG1136	(ABC) transporter
KTC41_RS01690	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KTC41_RS01695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KTC41_RS01700	COG0729	surface antigen
KTC41_RS01710	COG2105	PFAM AIG2 family protein
KTC41_RS01715	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KTC41_RS01725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KTC41_RS01730	COG0163	prenyltransferase activity
KTC41_RS01740	COG1178	ABC-type Fe3 transport system permease component
KTC41_RS01745	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KTC41_RS01750	COG3028	Belongs to the UPF0307 family
KTC41_RS01755	COG0312	modulator of DNA gyrase
KTC41_RS01760	COG2239	Acts as a magnesium transporter
KTC41_RS01765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KTC41_RS01770	COG1660	Displays ATPase and GTPase activities
KTC41_RS01775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KTC41_RS01780	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KTC41_RS01790	COG1137	ATPase activity
KTC41_RS01795	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KTC41_RS01810	COG0517	IMP dehydrogenase activity
KTC41_RS01810	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KTC41_RS01820	COG3385	transposase activity
KTC41_RS01825	COG1127	ABC transporter
KTC41_RS01830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KTC41_RS01835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KTC41_RS01840	COG2854	intermembrane phospholipid transfer
KTC41_RS01850	COG5007	Belongs to the BolA IbaG family
KTC41_RS01855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KTC41_RS01865	COG0251	oxidation-reduction process
KTC41_RS01875	COG0540	Belongs to the ATCase OTCase family
KTC41_RS01885	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KTC41_RS01895	COG0564	pseudouridine synthase activity
KTC41_RS01900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KTC41_RS01905	COG0525	valine-tRNA ligase activity
KTC41_RS01910	COG2927	DNA polymerase III (CHI subunit)
KTC41_RS01915	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KTC41_RS01920	COG0795	lipopolysaccharide-transporting ATPase activity
KTC41_RS01925	COG0795	lipopolysaccharide-transporting ATPase activity
KTC41_RS01940	COG3437	response regulator, receiver
KTC41_RS01985	COG0066	3-isopropylmalate dehydratase activity
KTC41_RS01990	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KTC41_RS01995	COG0473	3-isopropylmalate dehydrogenase activity
KTC41_RS02015	COG0583	DNA-binding transcription factor activity
KTC41_RS02020	COG1022	Amp-dependent synthetase and ligase
KTC41_RS02025	COG0028	Belongs to the TPP enzyme family
KTC41_RS02030	COG0440	acetolactate synthase activity
KTC41_RS02035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KTC41_RS02040	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KTC41_RS02045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KTC41_RS02055	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KTC41_RS02060	COG3079	Belongs to the UPF0149 family
KTC41_RS02065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KTC41_RS02070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KTC41_RS02085	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KTC41_RS02095	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KTC41_RS02100	COG1595	DNA-templated transcription, initiation
KTC41_RS02115	COG3086	response to oxidative stress
KTC41_RS02120	COG0481	GTPase activity
KTC41_RS02130	COG0571	ribonuclease III activity
KTC41_RS02135	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KTC41_RS02140	COG1381	Involved in DNA repair and RecF pathway recombination
KTC41_RS02145	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KTC41_RS02150	COG0736	holo-[acyl-carrier-protein] synthase activity
KTC41_RS02165	COG5001	Diguanylate cyclase
KTC41_RS02175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KTC41_RS02180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KTC41_RS02185	COG3956	TIGRFAM MazG family protein
KTC41_RS02190	COG0504	CTP synthase activity
KTC41_RS02195	COG0148	phosphopyruvate hydratase activity
KTC41_RS02200	COG0617	tRNA 3'-terminal CCA addition
KTC41_RS02205	COG3267	Type II secretory pathway component ExeA
KTC41_RS02205	COG3409	Peptidoglycan-binding domain 1 protein
KTC41_RS02215	COG4991	sh3 domain protein
KTC41_RS02220	COG0306	phosphate transporter
KTC41_RS02225	COG1392	Phosphate transport regulator
KTC41_RS02230	COG3025	triphosphatase activity
KTC41_RS02235	COG3385	transposase activity
KTC41_RS02240	COG0840	transmembrane signaling receptor activity
KTC41_RS02245	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KTC41_RS02250	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KTC41_RS02250	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KTC41_RS02255	COG1538	Outer membrane efflux protein
KTC41_RS02260	COG0494	nUDIX hydrolase
KTC41_RS02265	COG3151	Protein conserved in bacteria
KTC41_RS02275	COG3150	esterase
KTC41_RS02280	COG0187	DNA topoisomerase II activity
KTC41_RS02285	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KTC41_RS02295	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KTC41_RS02300	COG0237	dephospho-CoA kinase activity
KTC41_RS02310	COG1459	type II secretion system
KTC41_RS02315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KTC41_RS02335	COG0716	FMN binding
KTC41_RS02340	COG4974	Belongs to the 'phage' integrase family
KTC41_RS02345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KTC41_RS02350	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KTC41_RS02355	COG2186	Transcriptional regulator
KTC41_RS02360	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KTC41_RS02365	COG0508	dehydrogenase complex catalyzes the overall conversion of
KTC41_RS02370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KTC41_RS02385	COG3116	cell division
KTC41_RS02390	COG0768	penicillin binding
KTC41_RS02395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KTC41_RS02400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KTC41_RS02410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KTC41_RS02415	COG0772	Belongs to the SEDS family
KTC41_RS02420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KTC41_RS02425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KTC41_RS02430	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KTC41_RS02435	COG0849	cell division
KTC41_RS02440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KTC41_RS02445	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KTC41_RS02455	COG0653	protein targeting
KTC41_RS02460	COG0494	nUDIX hydrolase
KTC41_RS02465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KTC41_RS02475	COG0505	Belongs to the CarA family
KTC41_RS02480	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KTC41_RS02500	COG0730	response to heat
KTC41_RS02505	COG0583	DNA-binding transcription factor activity
KTC41_RS02510	COG2860	membrane
KTC41_RS02515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KTC41_RS02525	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KTC41_RS02535	COG0493	'glutamate synthase
KTC41_RS02540	COG0067	glutamate synthase
KTC41_RS02540	COG0069	glutamate synthase activity
KTC41_RS02540	COG0070	glutamate synthase
KTC41_RS02550	COG0067	glutamate synthase
KTC41_RS02550	COG0069	glutamate synthase activity
KTC41_RS02550	COG0070	glutamate synthase
KTC41_RS02555	COG1242	4 iron, 4 sulfur cluster binding
KTC41_RS02560	COG4251	negative regulation of phosphorylation
KTC41_RS02560	COG3706	GGDEF domain
KTC41_RS02560	COG2203	Gaf domain
KTC41_RS02560	COG5001	Diguanylate cyclase
KTC41_RS02565	COG0784	Response regulator, receiver
KTC41_RS02565	COG2198	Histidine kinase
KTC41_RS02565	COG5002	protein histidine kinase activity
KTC41_RS02570	COG0745	RESPONSE REGULATOR receiver
KTC41_RS02580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KTC41_RS02600	COG0083	homoserine kinase activity
KTC41_RS02605	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KTC41_RS02610	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
KTC41_RS02615	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KTC41_RS02620	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KTC41_RS02635	COG1115	amino acid carrier protein
KTC41_RS02640	COG3022	response to hydroperoxide
KTC41_RS02650	COG0084	hydrolase, TatD family'
KTC41_RS02655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KTC41_RS02665	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KTC41_RS02670	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KTC41_RS02675	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KTC41_RS02680	COG0813	purine-nucleoside phosphorylase activity
KTC41_RS02690	COG0560	Phosphoserine phosphatase
KTC41_RS02700	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KTC41_RS02705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KTC41_RS02710	COG1022	Amp-dependent synthetase and ligase
KTC41_RS02725	COG3250	beta-galactosidase activity
KTC41_RS02730	COG1609	Transcriptional regulator
KTC41_RS02735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KTC41_RS02755	COG0456	acetyltransferase
KTC41_RS02765	COG2171	N-acyltransferase activity
KTC41_RS02770	COG3141	response to X-ray
KTC41_RS02785	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KTC41_RS02790	COG1074	ATP-dependent DNA helicase activity
KTC41_RS02795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KTC41_RS02805	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KTC41_RS02805	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KTC41_RS02815	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KTC41_RS02820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KTC41_RS02825	COG2166	iron-sulfur cluster assembly
KTC41_RS02830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KTC41_RS02835	COG0693	protein deglycase activity
KTC41_RS02840	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KTC41_RS02845	COG3248	Nucleoside-binding outer membrane protein
KTC41_RS02855	COG1595	DNA-templated transcription, initiation
KTC41_RS02865	COG2211	Major facilitator Superfamily
KTC41_RS02870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KTC41_RS02880	COG2813	Specifically methylates the guanine in position
KTC41_RS02885	COG0271	Belongs to the BolA IbaG family
KTC41_RS02890	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KTC41_RS02895	COG1805	sodium ion transport
KTC41_RS02900	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KTC41_RS02905	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KTC41_RS02910	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KTC41_RS02915	COG2871	sodium ion transport
KTC41_RS02920	COG1477	protein flavinylation
KTC41_RS02940	COG3706	GGDEF domain
KTC41_RS02945	COG0733	neurotransmitter:sodium symporter activity
KTC41_RS02955	COG0189	ligase activity
KTC41_RS02960	COG4067	protein conserved in archaea
KTC41_RS02960	COG0189	ligase activity
KTC41_RS02965	COG2195	Cleaves the N-terminal amino acid of tripeptides
KTC41_RS02970	COG2252	PERMEase
KTC41_RS02975	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KTC41_RS02980	COG1073	alpha beta
KTC41_RS02990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KTC41_RS02995	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KTC41_RS03000	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KTC41_RS03005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KTC41_RS03005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KTC41_RS03020	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KTC41_RS03025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KTC41_RS03030	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KTC41_RS03035	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KTC41_RS03045	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KTC41_RS03050	COG0024	Methionine aminopeptidase
KTC41_RS03055	COG0052	Belongs to the universal ribosomal protein uS2 family
KTC41_RS03060	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KTC41_RS03065	COG0528	UMP kinase activity
KTC41_RS03070	COG0233	cytoplasmic translational termination
KTC41_RS03075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KTC41_RS03080	COG0575	Belongs to the CDS family
KTC41_RS03085	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KTC41_RS03090	COG0750	zinc metalloprotease
KTC41_RS03100	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
KTC41_RS03105	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KTC41_RS03110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KTC41_RS03115	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KTC41_RS03120	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KTC41_RS03125	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KTC41_RS03130	COG0587	DNA-directed DNA polymerase activity
KTC41_RS03135	COG0825	malonyl-CoA metabolic process
KTC41_RS03140	COG0037	tRNA processing
KTC41_RS03150	COG0347	Belongs to the P(II) protein family
KTC41_RS03155	COG3021	interspecies interaction between organisms
KTC41_RS03160	COG0741	lytic transglycosylase activity
KTC41_RS03160	COG1388	LysM domain
KTC41_RS03165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KTC41_RS03170	COG2226	methyltransferase
KTC41_RS03175	COG0328	RNA-DNA hybrid ribonuclease activity
KTC41_RS03190	COG1960	acyl-CoA dehydrogenase activity
KTC41_RS03195	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KTC41_RS03200	COG0121	glutamine amidotransferase
KTC41_RS03205	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KTC41_RS03210	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KTC41_RS03215	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KTC41_RS03225	COG1187	pseudouridine synthase activity
KTC41_RS03230	COG2840	Smr protein MutS2
KTC41_RS03245	COG3735	TraB family
KTC41_RS03260	COG2217	Heavy metal translocating P-type atpase
KTC41_RS03260	COG2608	mercury ion transmembrane transporter activity
KTC41_RS03265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KTC41_RS03280	COG2375	cellular response to nickel ion
KTC41_RS03310	COG3385	transposase activity
KTC41_RS03330	COG0784	Response regulator, receiver
KTC41_RS03330	COG0835	chemotaxis
KTC41_RS03335	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KTC41_RS03340	COG1815	bacterial-type flagellum-dependent cell motility
KTC41_RS03355	COG1749	Flagellar hook protein flgE
KTC41_RS03360	COG4787	bacterial-type flagellum-dependent cell motility
KTC41_RS03370	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KTC41_RS03375	COG1706	bacterial-type flagellum-dependent cell motility
KTC41_RS03380	COG1705	Flagellar rod assembly protein muramidase FlgJ
KTC41_RS03380	COG3951	Flagellar rod assembly protein muramidase FlgJ
KTC41_RS03395	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KTC41_RS03400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KTC41_RS03485	COG0012	GTP binding
KTC41_RS03490	COG0193	aminoacyl-tRNA hydrolase activity
KTC41_RS03495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KTC41_RS03500	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KTC41_RS03505	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KTC41_RS03510	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KTC41_RS03515	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KTC41_RS03520	COG2890	protein-(glutamine-N5) methyltransferase activity
KTC41_RS03530	COG2912	Transglutaminase-like superfamily
KTC41_RS03535	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KTC41_RS03540	COG0737	Belongs to the 5'-nucleotidase family
KTC41_RS03545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KTC41_RS03550	COG2233	PERMEase
KTC41_RS03570	COG1393	Belongs to the ArsC family
KTC41_RS03575	COG4783	chaperone-mediated protein folding
KTC41_RS03595	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KTC41_RS03610	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KTC41_RS03620	COG1876	peptidase activity
KTC41_RS03630	COG1393	Belongs to the ArsC family
KTC41_RS03650	COG2837	iron assimilation
KTC41_RS03655	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KTC41_RS03660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KTC41_RS03665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KTC41_RS03670	COG1334	flagellar protein FlaG
KTC41_RS03675	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KTC41_RS03685	COG1516	flagellar protein fliS
KTC41_RS03705	COG1677	Flagellar hook-basal body complex protein FliE
KTC41_RS03715	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KTC41_RS03720	COG1317	bacterial-type flagellum organization
KTC41_RS03745	COG1580	Controls the rotational direction of flagella during chemotaxis
KTC41_RS03770	COG1987	bacterial-type flagellum assembly
KTC41_RS03775	COG1684	flagellar biosynthetic protein fliR
KTC41_RS03785	COG2840	Smr protein MutS2
KTC41_RS03790	COG2890	protein-(glutamine-N5) methyltransferase activity
KTC41_RS03795	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KTC41_RS03800	COG2860	membrane
KTC41_RS03805	COG3101	peptidyl-lysine hydroxylation
KTC41_RS03815	COG0431	NADPH-dependent FMN reductase
KTC41_RS03820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KTC41_RS03820	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KTC41_RS03825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KTC41_RS03830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KTC41_RS03835	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KTC41_RS03840	COG0735	belongs to the Fur family
KTC41_RS03850	COG0583	DNA-binding transcription factor activity
KTC41_RS03860	COG1346	cytolysis
KTC41_RS03875	COG0596	Alpha beta hydrolase
KTC41_RS03880	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KTC41_RS03885	COG0033	Phosphoglucomutase
KTC41_RS03895	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KTC41_RS03900	COG0372	Belongs to the citrate synthase family
KTC41_RS03905	COG2009	succinate dehydrogenase
KTC41_RS03910	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KTC41_RS03915	COG1053	succinate dehydrogenase
KTC41_RS03925	COG0567	Dehydrogenase, E1 component
KTC41_RS03930	COG0508	dehydrogenase complex catalyzes the overall conversion of
KTC41_RS03935	COG0045	succinate-CoA ligase (ADP-forming) activity
KTC41_RS03945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KTC41_RS03950	COG1121	(ABC) transporter
KTC41_RS03955	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KTC41_RS03960	COG4977	sequence-specific DNA binding
KTC41_RS03965	COG1918	ferrous iron import across plasma membrane
KTC41_RS03985	COG0018	arginyl-trna synthetase
KTC41_RS03995	COG1025	Belongs to the peptidase M16 family
KTC41_RS04000	COG2062	phosphohistidine phosphatase, SixA
KTC41_RS04030	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KTC41_RS04035	COG0784	Response regulator, receiver
KTC41_RS04035	COG0643	Histidine kinase
KTC41_RS04035	COG2198	Histidine kinase
KTC41_RS04040	COG2201	protein-glutamate methylesterase activity
KTC41_RS04045	COG1192	Involved in chromosome partitioning
KTC41_RS04055	COG0835	chemotaxis
KTC41_RS04065	COG4133	protoheme IX ABC transporter activity
KTC41_RS04070	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KTC41_RS04075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KTC41_RS04085	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KTC41_RS04090	COG1138	Cytochrome C-type biogenesis protein
KTC41_RS04095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KTC41_RS04100	COG3088	subunit of a heme lyase
KTC41_RS04100	COG4235	cytochrome complex assembly
KTC41_RS04110	COG2853	Lipoprotein
KTC41_RS04130	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KTC41_RS04135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KTC41_RS04140	COG0123	including yeast histone deacetylase and acetoin utilization protein
KTC41_RS04155	COG3083	sulfuric ester hydrolase activity
KTC41_RS04160	COG3082	Protein of unknown function (DUF1414)
KTC41_RS04165	COG3081	Nucleoid-associated protein
KTC41_RS04175	COG1757	Na H antiporter
KTC41_RS04180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KTC41_RS04185	COG2095	MarC family integral membrane protein
KTC41_RS04190	COG1012	belongs to the aldehyde dehydrogenase family
KTC41_RS04190	COG1454	alcohol dehydrogenase
KTC41_RS04200	COG1530	ribonuclease E activity
KTC41_RS04205	COG0564	pseudouridine synthase activity
KTC41_RS04210	COG0424	maF-like protein
KTC41_RS04215	COG1399	metal-binding, possibly nucleic acid-binding protein
KTC41_RS04220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KTC41_RS04225	COG0416	fatty acid biosynthetic process
KTC41_RS04230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KTC41_RS04240	COG1028	Short-chain dehydrogenase reductase Sdr
KTC41_RS04245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KTC41_RS04250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KTC41_RS04255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KTC41_RS04260	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KTC41_RS04265	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KTC41_RS04275	COG0084	hydrolase, TatD family'
KTC41_RS04280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KTC41_RS04280	COG1263	PTS System
KTC41_RS04295	COG4667	esterase of the alpha-beta hydrolase superfamily
KTC41_RS04305	COG1940	carbohydrate kinase activity
KTC41_RS04310	COG0835	chemotaxis
KTC41_RS04310	COG0784	Response regulator, receiver
KTC41_RS04315	COG3385	transposase activity
KTC41_RS04345	COG2226	methyltransferase
KTC41_RS04355	COG0676	glucose-6-phosphate 1-epimerase activity
KTC41_RS04360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KTC41_RS04365	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KTC41_RS04375	COG3139	Protein of unknown function (DUF1315)
KTC41_RS04380	COG0252	asparaginase activity
KTC41_RS04385	COG0616	signal peptide processing
KTC41_RS04390	COG0446	pyridine nucleotide-disulphide oxidoreductase
KTC41_RS04390	COG1902	pentaerythritol trinitrate reductase activity
KTC41_RS04395	COG0788	formyltetrahydrofolate deformylase activity
KTC41_RS04405	COG1199	ATP-dependent helicase activity
KTC41_RS04410	COG1214	PFAM Peptidase M22, glycoprotease
KTC41_RS04425	COG0596	Alpha beta hydrolase
KTC41_RS04430	COG0318	PFAM AMP-dependent synthetase and ligase
KTC41_RS04435	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KTC41_RS04450	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KTC41_RS04455	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KTC41_RS04460	COG0436	Aminotransferase
KTC41_RS04465	COG1169	isochorismate synthase
KTC41_RS04470	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KTC41_RS04475	COG0596	Alpha beta hydrolase
KTC41_RS04495	COG3135	benzoate transporter
KTC41_RS04500	COG1396	sequence-specific DNA binding
KTC41_RS04505	COG0840	transmembrane signaling receptor activity
KTC41_RS04535	COG3015	lipoprotein NlpE involved in copper resistance
KTC41_RS04540	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KTC41_RS04545	COG2894	cell division
KTC41_RS04550	COG0850	regulation of cytokinetic process
KTC41_RS04555	COG3100	YcgL domain-containing protein
KTC41_RS04560	COG2951	lytic endotransglycosylase activity
KTC41_RS04570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KTC41_RS04580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KTC41_RS04600	COG4264	IucA IucC family
KTC41_RS04610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KTC41_RS04615	COG1120	ATPase activity
KTC41_RS04645	COG5001	Diguanylate cyclase
KTC41_RS04645	COG3300	MHYT domain
KTC41_RS04655	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KTC41_RS04660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KTC41_RS04665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KTC41_RS04670	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KTC41_RS04680	COG4191	Histidine kinase
KTC41_RS04690	COG0544	peptidyl-prolyl cis-trans isomerase activity
KTC41_RS04700	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KTC41_RS04705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KTC41_RS04710	COG0776	regulation of translation
KTC41_RS04715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KTC41_RS04720	COG1555	photosystem II stabilization
KTC41_RS04725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KTC41_RS04730	COG0539	negative regulation of cytoplasmic translation
KTC41_RS04735	COG0776	regulation of translation
KTC41_RS04740	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
KTC41_RS04745	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KTC41_RS04765	COG0583	DNA-binding transcription factor activity
KTC41_RS04775	COG0686	Belongs to the AlaDH PNT family
KTC41_RS04785	COG1674	ftsk spoiiie
KTC41_RS04790	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KTC41_RS04795	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KTC41_RS04800	COG2186	Transcriptional regulator
KTC41_RS04815	COG0537	adenosine 5'-monophosphoramidase activity
KTC41_RS04840	COG3150	esterase
KTC41_RS04845	COG1252	NADH dehydrogenase
KTC41_RS04860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KTC41_RS04870	COG4591	ABC-type transport system involved in lipoprotein release permease component
KTC41_RS04875	COG1136	(ABC) transporter
KTC41_RS04880	COG4591	ABC-type transport system involved in lipoprotein release permease component
KTC41_RS04890	COG0658	competence protein
KTC41_RS04890	COG2333	competence protein COMEC
KTC41_RS04895	COG1132	(ABC) transporter
KTC41_RS04900	COG1663	tetraacyldisaccharide 4'-kinase activity
KTC41_RS04905	COG2835	tetraacyldisaccharide 4'-kinase activity
KTC41_RS04910	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KTC41_RS04915	COG2719	SpoVR family
KTC41_RS04920	COG2718	Belongs to the UPF0229 family
KTC41_RS04925	COG2766	serine protein kinase
KTC41_RS04930	COG3013	Belongs to the UPF0304 family
KTC41_RS04940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KTC41_RS04945	COG0840	transmembrane signaling receptor activity
KTC41_RS04955	COG1882	Formate acetyltransferase
KTC41_RS04985	COG0708	Exodeoxyribonuclease III
KTC41_RS05000	COG0730	response to heat
KTC41_RS05005	COG1199	ATP-dependent helicase activity
KTC41_RS05020	COG3012	SEC-C Motif Domain Protein
KTC41_RS05025	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KTC41_RS05030	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KTC41_RS05035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KTC41_RS05040	COG0215	cysteine-tRNA ligase activity
KTC41_RS05045	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KTC41_RS05050	COG0632	four-way junction helicase activity
KTC41_RS05060	COG1271	oxidase subunit
KTC41_RS05065	COG1294	oxidase, subunit
KTC41_RS05070	COG4890	Cyd operon protein YbgT
KTC41_RS05080	COG0824	Thioesterase
KTC41_RS05085	COG0811	peptide transport
KTC41_RS05100	COG0823	Involved in the tonB-independent uptake of proteins
KTC41_RS05105	COG2885	chlorophyll binding
KTC41_RS05115	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KTC41_RS05125	COG0784	Response regulator, receiver
KTC41_RS05125	COG5002	protein histidine kinase activity
KTC41_RS05135	COG1482	cell wall glycoprotein biosynthetic process
KTC41_RS05140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KTC41_RS05140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KTC41_RS05140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KTC41_RS05145	COG2207	Transcriptional regulator
KTC41_RS05155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KTC41_RS05160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KTC41_RS05165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KTC41_RS05175	COG1012	belongs to the aldehyde dehydrogenase family
KTC41_RS05180	COG3284	Transcriptional regulator
KTC41_RS05185	COG4628	conserved protein (DUF2132)
KTC41_RS05215	COG4409	exo-alpha-(2->6)-sialidase activity
KTC41_RS05220	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KTC41_RS05225	COG1940	carbohydrate kinase activity
KTC41_RS05235	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KTC41_RS05240	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KTC41_RS05245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KTC41_RS05250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KTC41_RS05255	COG1737	Transcriptional regulator
KTC41_RS05260	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
KTC41_RS05265	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
KTC41_RS05275	COG0582	viral genome integration into host DNA
KTC41_RS05285	COG2200	EAL domain
KTC41_RS05295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KTC41_RS05305	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KTC41_RS05305	COG3008	intermembrane lipid transfer
KTC41_RS05310	COG2995	paraquat-inducible protein a
KTC41_RS05315	COG1309	transcriptional regulator
KTC41_RS05320	COG1012	belongs to the aldehyde dehydrogenase family
KTC41_RS05345	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KTC41_RS05350	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KTC41_RS05360	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KTC41_RS05375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KTC41_RS05380	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KTC41_RS05385	COG0297	glycogen (starch) synthase activity
KTC41_RS05405	COG3070	regulator of competence-specific genes
KTC41_RS05410	COG1609	Transcriptional regulator
KTC41_RS05415	COG3381	protein complex oligomerization
KTC41_RS05420	COG0745	RESPONSE REGULATOR receiver
KTC41_RS05425	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KTC41_RS05430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KTC41_RS05435	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
KTC41_RS05440	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KTC41_RS05460	COG1032	radical SAM domain protein
KTC41_RS05480	COG0583	DNA-binding transcription factor activity
KTC41_RS05485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KTC41_RS05495	COG2350	Protein conserved in bacteria
KTC41_RS05500	COG1607	acyl-coa hydrolase
KTC41_RS05515	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KTC41_RS05520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KTC41_RS05530	COG2116	formate transmembrane transporter activity
KTC41_RS05535	COG4459	periplasmic nitrate reductase
KTC41_RS05540	COG3005	denitrification pathway
KTC41_RS05545	COG0243	molybdopterin cofactor binding
KTC41_RS05560	COG1227	inorganic diphosphatase activity
KTC41_RS05580	COG4172	Belongs to the ABC transporter superfamily
KTC41_RS05590	COG4171	peptide transport system, permease
KTC41_RS05595	COG4168	peptide transport system, permease
KTC41_RS05605	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KTC41_RS05610	COG1842	Phage shock protein A
KTC41_RS05630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KTC41_RS05635	COG2818	Glycosylase
KTC41_RS05640	COG0626	cystathionine gamma-synthase activity
KTC41_RS05650	COG0733	neurotransmitter:sodium symporter activity
KTC41_RS05655	COG0564	pseudouridine synthase activity
KTC41_RS05660	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KTC41_RS05665	COG4136	ATPase activity
KTC41_RS05670	COG4135	transport system, permease component
KTC41_RS05675	COG4134	Bacterial extracellular solute-binding protein
KTC41_RS05685	COG3313	Fe-S protein
KTC41_RS05695	COG0814	amino acid
KTC41_RS05705	COG2239	Acts as a magnesium transporter
KTC41_RS05710	COG0784	Response regulator, receiver
KTC41_RS05710	COG2205	protein histidine kinase activity
KTC41_RS05745	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KTC41_RS05765	COG1061	Type III restriction enzyme res subunit
KTC41_RS05770	COG1187	pseudouridine synthase activity
KTC41_RS05775	COG2814	Major facilitator Superfamily
KTC41_RS05785	COG0702	epimerase
KTC41_RS05790	COG0534	Mate efflux family protein
KTC41_RS05795	COG4181	ATPase activity
KTC41_RS05800	COG0577	efflux transmembrane transporter activity
KTC41_RS05810	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KTC41_RS05820	COG1748	Saccharopine dehydrogenase
KTC41_RS05835	COG1538	Outer membrane efflux protein
KTC41_RS05870	COG0583	DNA-binding transcription factor activity
KTC41_RS05880	COG1451	nucleotide metabolic process
KTC41_RS05895	COG3063	Type IV pilus biogenesis stability protein PilW
KTC41_RS05900	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KTC41_RS05920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KTC41_RS05935	COG3290	protein histidine kinase activity
KTC41_RS05940	COG4565	transcriptional regulatory protein
KTC41_RS05950	COG0784	Response regulator, receiver
KTC41_RS05950	COG0835	chemotaxis
KTC41_RS05960	COG3385	transposase activity
KTC41_RS06000	COG1085	galactose-1-phosphate uridylyltransferase
KTC41_RS06005	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KTC41_RS06010	COG2017	converts alpha-aldose to the beta-anomer
KTC41_RS06015	COG3385	transposase activity
KTC41_RS06025	COG3064	Membrane
KTC41_RS06035	COG0753	catalase activity
KTC41_RS06055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KTC41_RS06080	COG3097	Belongs to the UPF0267 family
KTC41_RS06105	COG0316	Belongs to the HesB IscA family
KTC41_RS06110	COG0719	Fe-S assembly protein
KTC41_RS06115	COG0396	ATPase activity
KTC41_RS06120	COG0719	Fe-S assembly protein
KTC41_RS06125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KTC41_RS06140	COG1780	Probably involved in ribonucleotide reductase function
KTC41_RS06145	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KTC41_RS06155	COG1271	oxidase subunit
KTC41_RS06160	COG1294	oxidase, subunit
KTC41_RS06180	COG2723	6-phospho-beta-galactosidase activity
KTC41_RS06185	COG1609	Transcriptional regulator
KTC41_RS06190	COG0251	oxidation-reduction process
KTC41_RS06195	COG2731	YhcH YjgK YiaL family protein
KTC41_RS06200	COG0584	glycerophosphoryl diester phosphodiesterase
KTC41_RS06205	COG1349	DNA-binding transcription factor activity
KTC41_RS06210	COG3842	ATPase activity
KTC41_RS06215	COG0395	ABC-type sugar transport system, permease component
KTC41_RS06220	COG1175	transmembrane transport
KTC41_RS06235	COG0811	peptide transport
KTC41_RS06240	COG0811	peptide transport
KTC41_RS06245	COG0848	biopolymer transport protein
KTC41_RS06250	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KTC41_RS06260	COG1793	dna ligase
KTC41_RS06270	COG0534	Mate efflux family protein
KTC41_RS06280	COG3001	Fructosamine kinase
KTC41_RS06290	COG0791	NLP P60 protein
KTC41_RS06295	COG0840	transmembrane signaling receptor activity
KTC41_RS06305	COG3148	PFAM DTW domain containing protein
KTC41_RS06310	COG1940	carbohydrate kinase activity
KTC41_RS06320	COG0303	'Molybdopterin
KTC41_RS06325	COG0746	molybdenum cofactor guanylyltransferase activity
KTC41_RS06330	COG3842	ATPase activity
KTC41_RS06335	COG4662	Binding-protein-dependent transport system inner membrane component
KTC41_RS06345	COG2204	response regulator
KTC41_RS06350	COG3852	Histidine kinase
KTC41_RS06355	COG0488	(ABC) transporter
KTC41_RS06360	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KTC41_RS06390	COG3383	formate dehydrogenase (NAD+) activity
KTC41_RS06390	COG3383	formate dehydrogenase (NAD+) activity
KTC41_RS06395	COG0437	4 iron, 4 sulfur cluster binding
KTC41_RS06410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KTC41_RS06415	COG1666	GTP binding
KTC41_RS06420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KTC41_RS06435	COG2996	Protein conserved in bacteria
KTC41_RS06445	COG3008	intermembrane lipid transfer
KTC41_RS06450	COG2995	paraquat-inducible protein a
KTC41_RS06455	COG1132	(ABC) transporter
KTC41_RS06460	COG1956	GAF domain-containing protein
KTC41_RS06465	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KTC41_RS06480	COG0308	aminopeptidase N
KTC41_RS06495	COG0167	dihydroorotate dehydrogenase activity
KTC41_RS06505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KTC41_RS06505	COG0116	Belongs to the methyltransferase superfamily
KTC41_RS06515	COG0488	(ABC) transporter
KTC41_RS06530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KTC41_RS06535	COG1067	ATP-dependent peptidase activity
KTC41_RS06540	COG3120	sequence-specific DNA binding
KTC41_RS06555	COG0784	Response regulator, receiver
KTC41_RS06555	COG2205	protein histidine kinase activity
KTC41_RS06570	COG3278	Belongs to the heme-copper respiratory oxidase family
KTC41_RS06585	COG2010	Cytochrome c
KTC41_RS06595	COG2217	Heavy metal translocating P-type atpase
KTC41_RS06610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KTC41_RS06615	COG0589	response to stress
KTC41_RS06620	COG0037	tRNA processing
KTC41_RS06640	COG3842	ATPase activity
KTC41_RS06650	COG1177	transmembrane transport
KTC41_RS06660	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KTC41_RS06675	COG1115	amino acid carrier protein
KTC41_RS06680	COG1280	lysine exporter protein (LysE YggA)
KTC41_RS06705	COG3501	Rhs element vgr protein
KTC41_RS06715	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KTC41_RS06720	COG0513	Belongs to the DEAD box helicase family
KTC41_RS06725	COG0840	transmembrane signaling receptor activity
KTC41_RS06730	COG3290	protein histidine kinase activity
KTC41_RS06730	COG0840	transmembrane signaling receptor activity
KTC41_RS06735	COG0835	chemotaxis
KTC41_RS06740	COG2201	protein-glutamate methylesterase activity
KTC41_RS06750	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KTC41_RS06755	COG0784	Response regulator, receiver
KTC41_RS06755	COG2198	Histidine kinase
KTC41_RS06755	COG0643	Histidine kinase
KTC41_RS06760	COG0643	Histidine kinase
KTC41_RS06760	COG2198	Histidine kinase
KTC41_RS06770	COG0745	RESPONSE REGULATOR receiver
KTC41_RS06785	COG0477	Major facilitator Superfamily
KTC41_RS06790	COG0583	DNA-binding transcription factor activity
KTC41_RS06800	COG0402	S-adenosylhomocysteine deaminase activity
KTC41_RS06805	COG0443	Heat shock 70 kDa protein
KTC41_RS06815	COG1643	Atp-dependent helicase
KTC41_RS06845	COG0443	Heat shock 70 kDa protein
KTC41_RS06850	COG0443	Heat shock 70 kDa protein
KTC41_RS06880	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KTC41_RS06885	COG0602	queuosine metabolic process
KTC41_RS06890	COG0561	phosphatase activity
KTC41_RS06900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KTC41_RS06905	COG4597	amino acid ABC transporter
KTC41_RS06910	COG0765	amino acid transport
KTC41_RS06915	COG1126	abc transporter atp-binding protein
KTC41_RS06920	COG0670	Belongs to the BI1 family
KTC41_RS06925	COG2920	part of a sulfur-relay system
KTC41_RS06930	COG1254	Belongs to the acylphosphatase family
KTC41_RS06935	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KTC41_RS06940	COG3706	GGDEF domain
KTC41_RS06950	COG3850	Histidine kinase
KTC41_RS06950	COG4999	Histidine kinase
KTC41_RS06950	COG3437	response regulator, receiver
KTC41_RS06950	COG2205	protein histidine kinase activity
KTC41_RS06955	COG3437	response regulator, receiver
KTC41_RS06960	COG0625	glutathione transferase activity
KTC41_RS06970	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KTC41_RS06980	COG2195	Cleaves the N-terminal amino acid of tripeptides
KTC41_RS07010	COG0372	Belongs to the citrate synthase family
KTC41_RS07015	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KTC41_RS07040	COG0583	DNA-binding transcription factor activity
KTC41_RS07045	COG4771	TonB-dependent receptor
KTC41_RS07065	COG1129	ABC transporter
KTC41_RS07085	COG0745	RESPONSE REGULATOR receiver
KTC41_RS07090	COG5002	protein histidine kinase activity
KTC41_RS07095	COG3713	MltA-interacting MipA family protein
KTC41_RS07100	COG2990	Protein conserved in bacteria
KTC41_RS07110	COG4191	Histidine kinase
KTC41_RS07110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KTC41_RS07115	COG0471	metal ion transport
KTC41_RS07125	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KTC41_RS07140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KTC41_RS07150	COG3768	UPF0283 membrane protein
KTC41_RS07155	COG3106	COG3106 Predicted ATPase
KTC41_RS07170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KTC41_RS07175	COG0494	nUDIX hydrolase
KTC41_RS07180	COG0814	amino acid
KTC41_RS07185	COG1760	l-serine dehydratase
KTC41_RS07190	COG0720	synthase
KTC41_RS07195	COG0840	transmembrane signaling receptor activity
KTC41_RS07200	COG0017	Asparaginyl-tRNA synthetase
KTC41_RS07205	COG0351	phosphomethylpyrimidine kinase
KTC41_RS07210	COG1448	Aminotransferase
KTC41_RS07225	COG0840	transmembrane signaling receptor activity
KTC41_RS07230	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KTC41_RS07235	COG2943	transferase activity, transferring hexosyl groups
KTC41_RS07240	COG1609	Transcriptional regulator
KTC41_RS07245	COG3394	polysaccharide catabolic process
KTC41_RS07250	COG1486	melibiose metabolic process
KTC41_RS07255	COG1447	Phosphotransferase system cellobiose-specific component IIA
KTC41_RS07265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KTC41_RS07270	COG0726	polysaccharide deacetylase
KTC41_RS07275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KTC41_RS07280	COG1846	Transcriptional regulator
KTC41_RS07305	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KTC41_RS07320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KTC41_RS07325	COG3108	Peptidase M15
KTC41_RS07355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KTC41_RS07365	COG2814	Major facilitator Superfamily
KTC41_RS07375	COG1054	Belongs to the UPF0176 family
KTC41_RS07385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KTC41_RS07390	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KTC41_RS07395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KTC41_RS07425	COG0840	transmembrane signaling receptor activity
KTC41_RS07440	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KTC41_RS07445	COG4139	cobalamin transport
KTC41_RS07450	COG2988	succinylglutamate desuccinylase activity
KTC41_RS07465	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KTC41_RS07470	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KTC41_RS07475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KTC41_RS07480	COG1823	symporter activity
KTC41_RS07485	COG2925	Exonuclease
KTC41_RS07490	COG1380	Effector of murein hydrolase LrgA
KTC41_RS07495	COG1346	cytolysis
KTC41_RS07525	COG0776	regulation of translation
KTC41_RS07530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KTC41_RS07530	COG0072	phenylalanine-tRNA ligase activity
KTC41_RS07535	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KTC41_RS07570	COG0322	excinuclease ABC activity
KTC41_RS07575	COG2197	response regulator
KTC41_RS07580	COG0417	DNA replication proofreading
KTC41_RS07585	COG5001	Diguanylate cyclase
KTC41_RS07595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KTC41_RS07600	COG3099	Belongs to the UPF0263 family
KTC41_RS07615	COG1228	amidohydrolase
KTC41_RS07620	COG0010	Belongs to the arginase family
KTC41_RS07625	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KTC41_RS07630	COG2986	histidine ammonia-lyase
KTC41_RS07650	COG0277	FAD linked oxidase domain protein
KTC41_RS07650	COG0247	lactate metabolic process
KTC41_RS07685	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KTC41_RS07695	COG0281	malic enzyme
KTC41_RS07705	COG2949	membrane
KTC41_RS07710	COG3706	GGDEF domain
KTC41_RS07715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KTC41_RS07725	COG0492	ferredoxin-NADP+ reductase activity
KTC41_RS07730	COG4988	ABC transporter
KTC41_RS07735	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KTC41_RS07740	COG1187	pseudouridine synthase activity
KTC41_RS07745	COG0009	L-threonylcarbamoyladenylate synthase
KTC41_RS07750	COG0613	PHP domain protein
KTC41_RS07760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KTC41_RS07765	COG0512	Glutamine amidotransferase of anthranilate synthase
KTC41_RS07770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KTC41_RS07775	COG0135	phosphoribosylanthranilate isomerase activity
KTC41_RS07775	COG0134	indole-3-glycerol-phosphate synthase activity
KTC41_RS07780	COG0133	tryptophan synthase activity
KTC41_RS07785	COG0159	tryptophan synthase activity
KTC41_RS07795	COG1435	thymidine kinase activity
KTC41_RS07800	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KTC41_RS07805	COG1801	Protein of unknown function DUF72
KTC41_RS07810	COG4106	trans-aconitate 2-methyltransferase activity
KTC41_RS07815	COG0500	methyltransferase
KTC41_RS07820	COG4067	protein conserved in archaea
KTC41_RS07820	COG0189	ligase activity
KTC41_RS07835	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KTC41_RS07845	COG3852	Histidine kinase
KTC41_RS07860	COG3070	regulator of competence-specific genes
KTC41_RS07870	COG2431	L-lysine efflux transmembrane transporter activity
KTC41_RS07880	COG0076	glutamate decarboxylase activity
KTC41_RS07885	COG1737	Transcriptional regulator
KTC41_RS07890	COG1454	alcohol dehydrogenase
KTC41_RS07890	COG1012	belongs to the aldehyde dehydrogenase family
KTC41_RS07895	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KTC41_RS07900	COG3273	potassium ion transport
KTC41_RS07900	COG2985	domain, Protein
KTC41_RS07905	COG0542	response to heat
KTC41_RS07910	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KTC41_RS07915	COG1278	Cold shock
KTC41_RS07925	COG1187	pseudouridine synthase activity
KTC41_RS07930	COG0140	phosphoribosyl-ATP diphosphatase activity
KTC41_RS07930	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KTC41_RS07935	COG0107	imidazoleglycerol-phosphate synthase activity
KTC41_RS07940	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KTC41_RS07945	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KTC41_RS07950	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KTC41_RS07950	COG0131	Imidazoleglycerol-phosphate dehydratase
KTC41_RS07955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KTC41_RS07960	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KTC41_RS07965	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KTC41_RS07970	COG1757	Na H antiporter
KTC41_RS07975	COG2916	Histone family protein nucleoid-structuring protein H-NS
KTC41_RS07980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KTC41_RS07985	COG0482	sulfurtransferase activity
KTC41_RS07990	COG2915	High frequency lysogenization protein hflD homolog
KTC41_RS07995	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KTC41_RS08005	COG2268	Band 7 protein
KTC41_RS08015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KTC41_RS08030	COG0300	oxidoreductase activity
KTC41_RS08040	COG0501	Belongs to the peptidase M48B family
KTC41_RS08050	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KTC41_RS08055	COG2226	methyltransferase
KTC41_RS08060	COG0156	8-amino-7-oxononanoate synthase activity
KTC41_RS08065	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KTC41_RS08070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KTC41_RS08075	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KTC41_RS08080	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KTC41_RS08085	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KTC41_RS08090	COG0653	protein targeting
KTC41_RS08095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KTC41_RS08100	COG2199	diguanylate cyclase activity
KTC41_RS08100	COG2203	Gaf domain
KTC41_RS08110	COG4120	Belongs to the binding-protein-dependent transport system permease family
KTC41_RS08120	COG4628	conserved protein (DUF2132)
KTC41_RS08125	COG3092	negative regulation of chromosome organization
KTC41_RS08130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KTC41_RS08135	COG0857	belongs to the CobB CobQ family
KTC41_RS08135	COG0280	phosphate acetyltransferase
KTC41_RS08140	COG0435	Glutathione S-transferase
KTC41_RS08145	COG4608	Belongs to the ABC transporter superfamily
KTC41_RS08150	COG0444	Belongs to the ABC transporter superfamily
KTC41_RS08155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KTC41_RS08160	COG0601	transmembrane transport
KTC41_RS08180	COG2204	response regulator
KTC41_RS08185	COG3300	MHYT domain
KTC41_RS08185	COG5001	Diguanylate cyclase
KTC41_RS08190	COG4191	Histidine kinase
KTC41_RS08195	COG5002	protein histidine kinase activity
KTC41_RS08205	COG2201	protein-glutamate methylesterase activity
KTC41_RS08220	COG0009	L-threonylcarbamoyladenylate synthase
KTC41_RS08235	COG1881	PFAM PEBP family protein
KTC41_RS08260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KTC41_RS08265	COG0640	Transcriptional regulator
KTC41_RS08275	COG4735	regulation of single-species biofilm formation
KTC41_RS08285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KTC41_RS08290	COG0583	DNA-binding transcription factor activity
KTC41_RS08325	COG0732	type I restriction modification DNA specificity domain
KTC41_RS08350	COG1396	sequence-specific DNA binding
KTC41_RS08375	COG3706	GGDEF domain
KTC41_RS08395	COG1946	Acyl-CoA thioesterase
KTC41_RS08400	COG1522	sequence-specific DNA binding
KTC41_RS08410	COG0616	signal peptide processing
KTC41_RS08415	COG1028	Short-chain dehydrogenase reductase Sdr
KTC41_RS08420	COG2983	Belongs to the UPF0260 family
KTC41_RS08430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KTC41_RS08435	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KTC41_RS08445	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KTC41_RS08450	COG2832	Protein of unknown function (DUF454)
KTC41_RS08455	COG0745	RESPONSE REGULATOR receiver
KTC41_RS08460	COG0583	DNA-binding transcription factor activity
KTC41_RS08465	COG0778	Nitroreductase
KTC41_RS08470	COG1024	Enoyl-CoA hydratase
KTC41_RS08470	COG1250	3-hydroxyacyl-CoA dehydrogenase
KTC41_RS08475	COG0183	Belongs to the thiolase family
KTC41_RS08490	COG2067	long-chain fatty acid transport protein
KTC41_RS08495	COG2067	long-chain fatty acid transport protein
KTC41_RS08500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KTC41_RS08505	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
KTC41_RS08510	COG2982	Protein involved in outer membrane biogenesis
KTC41_RS08515	COG0572	uridine kinase
KTC41_RS08520	COG0489	protein tyrosine kinase activity
KTC41_RS08525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KTC41_RS08525	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KTC41_RS08545	COG0517	IMP dehydrogenase activity
KTC41_RS08545	COG0617	tRNA 3'-terminal CCA addition
KTC41_RS08545	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KTC41_RS08550	COG3706	GGDEF domain
KTC41_RS08555	COG0314	molybdopterin synthase activity
KTC41_RS08560	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KTC41_RS08565	COG0315	cyclic pyranopterin monophosphate synthase activity
KTC41_RS08570	COG0521	Mo-molybdopterin cofactor biosynthetic process
KTC41_RS08575	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KTC41_RS08580	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KTC41_RS08585	COG2198	Histidine kinase
KTC41_RS08590	COG2204	response regulator
KTC41_RS08595	COG0556	nucleotide-excision repair
KTC41_RS08605	COG4657	Part of a membrane complex involved in electron transport
KTC41_RS08610	COG2878	Part of a membrane complex involved in electron transport
KTC41_RS08615	COG4656	Part of a membrane complex involved in electron transport
KTC41_RS08630	COG4660	Part of a membrane complex involved in electron transport
KTC41_RS08635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KTC41_RS08640	COG0346	lactoylglutathione lyase activity
KTC41_RS08655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KTC41_RS08660	COG2056	Na+-H+ antiporter family
KTC41_RS08665	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KTC41_RS08670	COG1286	toxin biosynthetic process
KTC41_RS08675	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KTC41_RS08680	COG0285	dihydrofolate synthase activity
KTC41_RS08685	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KTC41_RS08690	COG0101	tRNA pseudouridine synthase activity
KTC41_RS08705	COG1263	PTS System
KTC41_RS08705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KTC41_RS08705	COG2190	(PTS) system
KTC41_RS08710	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KTC41_RS08715	COG1846	Transcriptional regulator
KTC41_RS08715	COG1940	carbohydrate kinase activity
KTC41_RS08720	COG4651	solute:proton antiporter activity
KTC41_RS08720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KTC41_RS08725	COG0367	asparagine synthase
KTC41_RS08730	COG0250	Participates in transcription elongation, termination and antitermination
KTC41_RS08740	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KTC41_RS08745	COG0563	adenylate kinase activity
KTC41_RS08750	COG0326	Molecular chaperone. Has ATPase activity
KTC41_RS08755	COG3710	Transcriptional regulator
KTC41_RS08770	COG0622	Phosphoesterase
KTC41_RS08775	COG1090	epimerase
KTC41_RS08780	COG0300	oxidoreductase activity
KTC41_RS08785	COG3118	belongs to the thioredoxin family
KTC41_RS08790	COG0330	HflC and HflK could
KTC41_RS08795	COG1585	Membrane protein implicated in regulation of membrane protease activity
KTC41_RS08800	COG0789	Transcriptional regulator
KTC41_RS08815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KTC41_RS08820	COG3115	cell septum assembly
KTC41_RS08825	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
KTC41_RS08830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KTC41_RS08835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KTC41_RS08845	COG2190	(PTS) system
KTC41_RS08850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KTC41_RS08855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KTC41_RS08860	COG1702	phosphate starvation-inducible protein PhoH
KTC41_RS08870	COG4535	Mg2 and Co2 transporter CorC
KTC41_RS08875	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KTC41_RS08880	COG2888	peptidyl-tyrosine sulfation
KTC41_RS08885	COG0495	leucyl-tRNA aminoacylation
KTC41_RS08890	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
KTC41_RS08895	COG1466	dna polymerase III delta subunit
KTC41_RS08900	COG0799	negative regulation of ribosome biogenesis
KTC41_RS08905	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KTC41_RS08910	COG0768	penicillin binding
KTC41_RS08915	COG0772	Belongs to the SEDS family
KTC41_RS08920	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KTC41_RS08925	COG1686	Belongs to the peptidase S11 family
KTC41_RS08930	COG2921	Belongs to the UPF0250 family
KTC41_RS08935	COG0321	lipoyl(octanoyl) transferase activity
KTC41_RS08940	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KTC41_RS08950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KTC41_RS08975	COG1596	polysaccharide export
KTC41_RS08985	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KTC41_RS09015	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KTC41_RS09025	COG0438	transferase activity, transferring glycosyl groups
KTC41_RS09035	COG1045	serine acetyltransferase
KTC41_RS09060	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KTC41_RS09065	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KTC41_RS09070	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KTC41_RS09075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KTC41_RS09105	COG0366	Alpha amylase catalytic
KTC41_RS09110	COG1263	PTS System
KTC41_RS09110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KTC41_RS09115	COG1609	Transcriptional regulator
KTC41_RS09120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KTC41_RS09125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KTC41_RS09130	COG2011	ABC-type metal ion transport system permease component
KTC41_RS09135	COG1464	Belongs to the NlpA lipoprotein family
KTC41_RS09140	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
KTC41_RS09150	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KTC41_RS09150	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KTC41_RS09165	COG1611	Belongs to the LOG family
KTC41_RS09170	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KTC41_RS09175	COG2363	Small membrane protein
KTC41_RS09180	COG0583	DNA-binding transcription factor activity
KTC41_RS09185	COG0301	tRNA thio-modification
KTC41_RS09185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KTC41_RS09195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KTC41_RS09200	COG1722	exodeoxyribonuclease VII activity
KTC41_RS09205	COG0142	geranyltranstransferase activity
KTC41_RS09210	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KTC41_RS09215	COG0564	pseudouridine synthase activity
KTC41_RS09220	COG3098	single-species biofilm formation
KTC41_RS09235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KTC41_RS09245	COG1671	Belongs to the UPF0178 family
KTC41_RS09250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KTC41_RS09255	COG0254	rRNA binding
KTC41_RS09260	COG1720	tRNA m6t6A37 methyltransferase activity
KTC41_RS09265	COG0442	prolyl-tRNA aminoacylation
KTC41_RS09285	COG3385	transposase activity
KTC41_RS09290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KTC41_RS09290	COG0047	phosphoribosylformylglycinamidine synthase activity
KTC41_RS09300	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KTC41_RS09310	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KTC41_RS09340	COG0484	heat shock protein binding
KTC41_RS09345	COG0443	Heat shock 70 kDa protein
KTC41_RS09355	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KTC41_RS09360	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KTC41_RS09365	COG0497	DNA recombination
KTC41_RS09370	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KTC41_RS09375	COG2914	Belongs to the UPF0125 (RnfH) family
KTC41_RS09380	COG2867	negative regulation of translational initiation
KTC41_RS09385	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KTC41_RS09395	COG0582	viral genome integration into host DNA
KTC41_RS09410	COG1104	cysteine desulfurase activity
KTC41_RS09475	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KTC41_RS09480	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KTC41_RS09485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KTC41_RS09495	COG0583	DNA-binding transcription factor activity
KTC41_RS09505	COG1115	amino acid carrier protein
KTC41_RS09520	COG1584	GPR1 FUN34 yaaH family protein
KTC41_RS09535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KTC41_RS09535	COG0519	Catalyzes the synthesis of GMP from XMP
KTC41_RS09540	COG0516	GMP reductase activity
KTC41_RS09540	COG0517	IMP dehydrogenase activity
KTC41_RS09545	COG1570	exodeoxyribonuclease VII activity
KTC41_RS09560	COG1160	GTP binding
KTC41_RS09565	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KTC41_RS09570	COG2976	Protein conserved in bacteria
KTC41_RS09575	COG0124	histidyl-tRNA synthetase
KTC41_RS09580	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KTC41_RS09595	COG0105	UTP biosynthetic process
KTC41_RS09600	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KTC41_RS09605	COG2975	iron-sulfur cluster assembly
KTC41_RS09610	COG0633	Ferredoxin
KTC41_RS09620	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KTC41_RS09630	COG0822	iron-sulfur transferase activity
KTC41_RS09640	COG1959	2 iron, 2 sulfur cluster binding
KTC41_RS09650	COG0483	inositol monophosphate 1-phosphatase activity
KTC41_RS09655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KTC41_RS09660	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KTC41_RS09665	COG1862	Preprotein translocase
KTC41_RS09675	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KTC41_RS09680	COG0517	IMP dehydrogenase activity
KTC41_RS09690	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KTC41_RS09695	COG0583	DNA-binding transcription factor activity
KTC41_RS09700	COG0450	alkyl hydroperoxide reductase
KTC41_RS09705	COG3142	Participates in the control of copper homeostasis
KTC41_RS09720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KTC41_RS09725	COG0581	inorganic phosphate transmembrane transporter activity
KTC41_RS09735	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KTC41_RS09740	COG0248	Ppx GppA phosphatase
KTC41_RS09750	COG5002	protein histidine kinase activity
KTC41_RS09755	COG0745	RESPONSE REGULATOR receiver
KTC41_RS09765	COG0826	peptidase U32
KTC41_RS09770	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KTC41_RS09815	COG0542	response to heat
KTC41_RS09825	COG0564	pseudouridine synthase activity
KTC41_RS09830	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KTC41_RS09835	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KTC41_RS09840	COG0077	Prephenate dehydratase
KTC41_RS09840	COG1605	Chorismate mutase
KTC41_RS09845	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KTC41_RS09850	COG5001	Diguanylate cyclase
KTC41_RS09860	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
KTC41_RS09870	COG0488	(ABC) transporter
KTC41_RS09880	COG0287	Prephenate dehydrogenase
KTC41_RS09880	COG1605	Chorismate mutase
KTC41_RS09885	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KTC41_RS09890	COG3275	phosphorelay sensor kinase activity
KTC41_RS09895	COG3279	Response regulator of the LytR AlgR family
KTC41_RS09905	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KTC41_RS09910	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KTC41_RS09920	COG1966	Carbon starvation protein
KTC41_RS09925	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KTC41_RS09930	COG1047	Peptidyl-prolyl cis-trans
KTC41_RS09935	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KTC41_RS09945	COG0196	riboflavin kinase activity
KTC41_RS09950	COG0728	peptidoglycan biosynthetic process
KTC41_RS09955	COG0268	Binds directly to 16S ribosomal RNA
KTC41_RS09960	COG0640	Transcriptional regulator
KTC41_RS09965	COG0583	DNA-binding transcription factor activity
KTC41_RS09970	COG1283	sodium-dependent phosphate transmembrane transporter activity
KTC41_RS09975	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KTC41_RS09980	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KTC41_RS09985	COG0730	response to heat
KTC41_RS09990	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
KTC41_RS09995	COG0494	nUDIX hydrolase
KTC41_RS10005	COG0667	Aldo Keto reductase
KTC41_RS10015	COG2204	response regulator
KTC41_RS10020	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KTC41_RS10040	COG0513	Belongs to the DEAD box helicase family
KTC41_RS10065	COG3153	acetyltransferase
KTC41_RS10070	COG3154	lipid carrier protein
KTC41_RS10080	COG0826	peptidase U32
KTC41_RS10085	COG0826	peptidase U32
KTC41_RS10110	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KTC41_RS10120	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KTC41_RS10125	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KTC41_RS10130	COG0195	Participates in both transcription termination and antitermination
KTC41_RS10135	COG0779	Required for maturation of 30S ribosomal subunits
KTC41_RS10150	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KTC41_RS10160	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KTC41_RS10165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KTC41_RS10170	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KTC41_RS10175	COG1534	Rna-binding protein
KTC41_RS10180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KTC41_RS10185	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KTC41_RS10190	COG2027	D-alanyl-D-alanine carboxypeptidase
KTC41_RS10195	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KTC41_RS10200	COG0739	heme binding
KTC41_RS10205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KTC41_RS10215	COG0316	Belongs to the HesB IscA family
KTC41_RS10220	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KTC41_RS10225	COG0628	permease
KTC41_RS10230	COG2813	Specifically methylates the guanine in position
KTC41_RS10235	COG2205	protein histidine kinase activity
KTC41_RS10235	COG0784	Response regulator, receiver
KTC41_RS10240	COG0747	negative chemotaxis
KTC41_RS10250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KTC41_RS10255	COG0444	Belongs to the ABC transporter superfamily
KTC41_RS10260	COG4608	Belongs to the ABC transporter superfamily
KTC41_RS10270	COG2971	BadF BadG BcrA BcrD
KTC41_RS10290	COG3842	ATPase activity
KTC41_RS10300	COG1840	ABC-type Fe3 transport system, periplasmic component
KTC41_RS10305	COG0004	ammonium transporteR
KTC41_RS10310	COG0347	Belongs to the P(II) protein family
KTC41_RS10315	COG3112	Uncharacterised protein family (UPF0231)
KTC41_RS10320	COG1049	propionate catabolic process, 2-methylcitrate cycle
KTC41_RS10325	COG1752	Esterase of the alpha-beta hydrolase superfamily
KTC41_RS10330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KTC41_RS10335	COG1643	Atp-dependent helicase
KTC41_RS10345	COG1489	DNA binding
KTC41_RS10355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KTC41_RS10365	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KTC41_RS10370	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KTC41_RS10375	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KTC41_RS10380	COG0842	Transport permease protein
KTC41_RS10385	COG1131	(ABC) transporter
KTC41_RS10390	COG0659	secondary active sulfate transmembrane transporter activity
KTC41_RS10395	COG0288	reversible hydration of carbon dioxide
KTC41_RS10410	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KTC41_RS10415	COG3107	peptidoglycan biosynthetic process
KTC41_RS10420	COG0792	nuclease activity
KTC41_RS10425	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KTC41_RS10430	COG2823	Periplasmic or secreted lipoprotein
KTC41_RS10435	COG2969	positive regulation of protein catabolic process
KTC41_RS10440	COG0625	glutathione transferase activity
KTC41_RS10445	COG2857	Cytochrome c1
KTC41_RS10450	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KTC41_RS10455	COG0723	plastoquinol--plastocyanin reductase activity
KTC41_RS10460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KTC41_RS10465	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KTC41_RS10470	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KTC41_RS10480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KTC41_RS10485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KTC41_RS10490	COG0335	large ribosomal subunit rRNA binding
KTC41_RS10495	COG0336	Belongs to the RNA methyltransferase TrmD family
KTC41_RS10500	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KTC41_RS10505	COG0228	four-way junction DNA binding
KTC41_RS10510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KTC41_RS10515	COG4137	Cytochrome C assembly protein
KTC41_RS10520	COG4536	flavin adenine dinucleotide binding
KTC41_RS10525	COG1854	S-ribosylhomocysteine lyase activity
KTC41_RS10530	COG2918	glutathione biosynthetic process
KTC41_RS10535	COG0612	Peptidase, M16
KTC41_RS10540	COG1238	metal cluster binding
KTC41_RS10550	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KTC41_RS10555	COG0511	ligase activity, forming carbon-carbon bonds
KTC41_RS10555	COG5016	pyruvate
KTC41_RS10560	COG3630	sodium ion export across plasma membrane
KTC41_RS10605	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KTC41_RS10610	COG0527	aspartate kinase activity
KTC41_RS10615	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KTC41_RS10620	COG2137	regulation of response to DNA damage stimulus
KTC41_RS10625	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KTC41_RS10635	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KTC41_RS10640	COG4208	sulfate ABC transporter
KTC41_RS10660	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KTC41_RS10665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KTC41_RS10675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KTC41_RS10680	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KTC41_RS10685	COG0585	pseudouridine synthase activity
KTC41_RS10690	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KTC41_RS10695	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KTC41_RS10700	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KTC41_RS10705	COG1968	undecaprenyl-diphosphatase activity
KTC41_RS10710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KTC41_RS10715	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KTC41_RS10720	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KTC41_RS10730	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KTC41_RS10735	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KTC41_RS10740	COG1610	YqeY-like protein
KTC41_RS10745	COG0358	DNA primase activity
KTC41_RS10765	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KTC41_RS10775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KTC41_RS10780	COG1349	DNA-binding transcription factor activity
KTC41_RS10800	COG1279	arginine transmembrane transporter activity
KTC41_RS10805	COG0668	transmembrane transport
KTC41_RS10810	COG0191	fructose-bisphosphate aldolase activity
KTC41_RS10815	COG0126	phosphoglycerate kinase activity
KTC41_RS10820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KTC41_RS10825	COG4771	TonB-dependent receptor
KTC41_RS10830	COG0583	DNA-binding transcription factor activity
KTC41_RS10835	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KTC41_RS10840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KTC41_RS10845	COG3091	SprT-like family
KTC41_RS10850	COG2356	endonuclease I
KTC41_RS10855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KTC41_RS10860	COG0189	ligase activity
KTC41_RS10865	COG1678	Uncharacterized ACR, COG1678
KTC41_RS10870	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KTC41_RS10875	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KTC41_RS10895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KTC41_RS10900	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KTC41_RS10905	COG0762	integral membrane protein
KTC41_RS10920	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KTC41_RS10925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KTC41_RS10930	COG2066	Belongs to the glutaminase family
KTC41_RS10935	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KTC41_RS10940	COG1194	a g-specific adenine glycosylase
KTC41_RS10945	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KTC41_RS10950	COG0741	lytic transglycosylase activity
KTC41_RS10975	COG0840	transmembrane signaling receptor activity
KTC41_RS11005	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KTC41_RS11010	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KTC41_RS11015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KTC41_RS11020	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KTC41_RS11025	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KTC41_RS11030	COG2967	ApaG domain
KTC41_RS11035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KTC41_RS11045	COG3610	response to peptide
KTC41_RS11050	COG2966	Psort location CytoplasmicMembrane, score
KTC41_RS11055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KTC41_RS11060	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KTC41_RS11065	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KTC41_RS11070	COG0142	geranyltranstransferase activity
KTC41_RS11075	COG0531	amino acid
KTC41_RS11080	COG0039	L-malate dehydrogenase activity
KTC41_RS11085	COG1438	arginine binding
KTC41_RS11090	COG2358	TRAP transporter, solute receptor (TAXI family
KTC41_RS11100	COG0589	response to stress
KTC41_RS11120	COG2235	arginine
KTC41_RS11125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KTC41_RS11130	COG1151	hydroxylamine reductase activity
KTC41_RS11135	COG0312	modulator of DNA gyrase
KTC41_RS11140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KTC41_RS11145	COG3164	Protein of unknown function
KTC41_RS11155	COG0424	maF-like protein
KTC41_RS11160	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KTC41_RS11165	COG1792	Involved in formation and maintenance of cell shape
KTC41_RS11170	COG1077	Cell shape determining protein MreB Mrl
KTC41_RS11200	COG2165	general secretion pathway protein
KTC41_RS11205	COG2165	general secretion pathway protein
KTC41_RS11215	COG1459	type II secretion system
KTC41_RS11220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KTC41_RS11230	COG3267	Type II secretory pathway component ExeA
KTC41_RS11230	COG3409	Peptidoglycan-binding domain 1 protein
KTC41_RS11255	COG2200	EAL domain
KTC41_RS11255	COG2199	diguanylate cyclase activity
KTC41_RS11260	COG0629	single-stranded DNA binding
KTC41_RS11275	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KTC41_RS11285	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KTC41_RS11290	COG0527	aspartate kinase activity
KTC41_RS11295	COG0646	methionine synthase
KTC41_RS11295	COG1410	methionine synthase
KTC41_RS11365	COG0175	sulfate reduction
KTC41_RS11375	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KTC41_RS11400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KTC41_RS11405	COG0735	belongs to the Fur family
KTC41_RS11425	COG0432	Pfam Uncharacterised protein family UPF0047
KTC41_RS11430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KTC41_RS11445	COG0359	binds to the 23S rRNA
KTC41_RS11450	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KTC41_RS11455	COG2965	DNA replication, synthesis of RNA primer
KTC41_RS11460	COG0360	Binds together with S18 to 16S ribosomal RNA
KTC41_RS11470	COG2906	2 iron, 2 sulfur cluster binding
KTC41_RS11475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KTC41_RS11480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KTC41_RS11485	COG0049	tRNA binding
KTC41_RS11500	COG2923	Belongs to the DsrF TusC family
KTC41_RS11505	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KTC41_RS11510	COG2964	Protein conserved in bacteria
KTC41_RS11515	COG0545	Peptidyl-prolyl cis-trans isomerase
KTC41_RS11525	COG2900	Belongs to the SlyX family
KTC41_RS11530	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KTC41_RS11535	COG0330	HflC and HflK could
KTC41_RS11540	COG0330	HflC and HflK could
KTC41_RS11545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KTC41_RS11550	COG1923	regulation of RNA biosynthetic process
KTC41_RS11555	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KTC41_RS11560	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KTC41_RS11565	COG0860	N-Acetylmuramoyl-L-alanine amidase
KTC41_RS11570	COG0802	atpase or kinase
KTC41_RS11575	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KTC41_RS11625	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KTC41_RS11630	COG1162	GTPase activity
KTC41_RS11635	COG0688	phosphatidylethanolamine metabolic process
KTC41_RS11640	COG0471	metal ion transport
KTC41_RS11650	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KTC41_RS11655	COG4942	peptidase
KTC41_RS11670	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KTC41_RS11675	COG2816	NAD+ diphosphatase activity
KTC41_RS11680	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
KTC41_RS11685	COG3385	transposase activity
KTC41_RS11690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KTC41_RS11695	COG0085	RNA polymerase activity
KTC41_RS11700	COG0222	ribosome binding
KTC41_RS11705	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KTC41_RS11715	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KTC41_RS11720	COG0250	Participates in transcription elongation, termination and antitermination
KTC41_RS11725	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KTC41_RS11730	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KTC41_RS11755	COG1072	(Pantothenic acid kinase))
KTC41_RS11765	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KTC41_RS11775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KTC41_RS11815	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KTC41_RS11830	COG3118	belongs to the thioredoxin family
KTC41_RS11835	COG0513	Belongs to the DEAD box helicase family
KTC41_RS11840	COG0248	Ppx GppA phosphatase
KTC41_RS11845	COG2205	protein histidine kinase activity
KTC41_RS11845	COG0784	Response regulator, receiver
KTC41_RS11850	COG2814	Major facilitator Superfamily
KTC41_RS11865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KTC41_RS11870	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KTC41_RS11875	COG0511	ligase activity, forming carbon-carbon bonds
KTC41_RS11880	COG0439	Biotin carboxylase
KTC41_RS11885	COG2264	protein methyltransferase activity
KTC41_RS11890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KTC41_RS11895	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KTC41_RS11910	COG1518	maintenance of DNA repeat elements
KTC41_RS11920	COG1857	crispr-associated protein
KTC41_RS11950	COG1609	Transcriptional regulator
KTC41_RS11955	COG0129	dihydroxy-acid dehydratase activity
KTC41_RS11960	COG3265	gluconokinase activity
KTC41_RS11965	COG2610	gluconate transmembrane transporter activity
KTC41_RS11970	COG0800	Aldolase
KTC41_RS11975	COG1982	Orn Lys Arg decarboxylase major
KTC41_RS11980	COG0531	amino acid
KTC41_RS11985	COG3710	Transcriptional regulator
KTC41_RS11990	COG0789	Transcriptional regulator
KTC41_RS12005	COG0151	Belongs to the GarS family
KTC41_RS12015	COG0776	regulation of translation
KTC41_RS12020	COG1253	flavin adenine dinucleotide binding
KTC41_RS12025	COG3068	Protein conserved in bacteria
KTC41_RS12035	COG0668	transmembrane transport
KTC41_RS12050	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KTC41_RS12055	COG3385	transposase activity
KTC41_RS12060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KTC41_RS12080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KTC41_RS12085	COG1215	transferase activity, transferring glycosyl groups
KTC41_RS12095	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KTC41_RS12100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KTC41_RS12120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KTC41_RS12145	COG0859	PFAM glycosyl transferase family 9
KTC41_RS12155	COG1519	Transferase
KTC41_RS12185	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KTC41_RS12185	COG2755	lipolytic protein G-D-S-L family
KTC41_RS12190	COG3642	lipopolysaccharide core region biosynthetic process
KTC41_RS12195	COG0859	PFAM glycosyl transferase family 9
KTC41_RS12200	COG0463	Glycosyl transferase, family 2
KTC41_RS12205	COG0859	PFAM glycosyl transferase family 9
KTC41_RS12210	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KTC41_RS12215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KTC41_RS12225	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KTC41_RS12230	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KTC41_RS12235	COG2003	Belongs to the UPF0758 family
KTC41_RS12245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KTC41_RS12250	COG1309	transcriptional regulator
KTC41_RS12255	COG1560	Kdo2-lipid A biosynthetic process
KTC41_RS12260	COG1560	Kdo2-lipid A biosynthetic process
KTC41_RS12265	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KTC41_RS12270	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KTC41_RS12275	COG1561	YicC-like family, N-terminal region
KTC41_RS12280	COG2862	Uncharacterized protein family, UPF0114
KTC41_RS12285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KTC41_RS12285	COG1263	PTS System
KTC41_RS12290	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KTC41_RS12310	COG1120	ATPase activity
KTC41_RS12315	COG4774	siderophore transport
KTC41_RS12320	COG1132	(ABC) transporter
KTC41_RS12330	COG0514	ATP-dependent DNA helicase (RecQ)
KTC41_RS12335	COG2962	Rard protein
KTC41_RS12345	COG1280	lysine exporter protein (LysE YggA)
KTC41_RS12350	COG0210	DNA helicase
KTC41_RS12360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KTC41_RS12365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KTC41_RS12375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KTC41_RS12380	COG0601	transmembrane transport
KTC41_RS12385	COG0747	negative chemotaxis
KTC41_RS12480	COG4964	Belongs to the GSP D family
KTC41_RS12515	COG1309	transcriptional regulator
KTC41_RS12520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KTC41_RS12525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KTC41_RS12530	COG2960	long-chain fatty acid transporting porin activity
KTC41_RS12535	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KTC41_RS12540	COG0583	DNA-binding transcription factor activity
KTC41_RS12610	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
KTC41_RS12615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KTC41_RS12620	COG1739	Uncharacterized protein family UPF0029
KTC41_RS12625	COG1024	Enoyl-CoA hydratase
KTC41_RS12625	COG1250	3-hydroxyacyl-CoA dehydrogenase
KTC41_RS12630	COG0183	Belongs to the thiolase family
KTC41_RS12635	COG0583	DNA-binding transcription factor activity
KTC41_RS12640	COG2814	Major facilitator Superfamily
KTC41_RS12650	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KTC41_RS12655	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KTC41_RS12660	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KTC41_RS12665	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KTC41_RS12670	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KTC41_RS12675	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KTC41_RS12685	COG0356	it plays a direct role in the translocation of protons across the membrane
KTC41_RS12690	COG3312	ion transport
KTC41_RS12695	COG1475	DNA binding
KTC41_RS12700	COG1192	Involved in chromosome partitioning
KTC41_RS12705	COG0357	Ribosomal RNA small subunit methyltransferase G
KTC41_RS12710	COG0445	tRNA wobble uridine modification
KTC41_RS12715	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KTC41_RS12720	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KTC41_RS12725	COG0706	membrane insertase activity
KTC41_RS12735	COG0594	ribonuclease P activity
KTC41_RS12740	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KTC41_RS12745	COG1126	abc transporter atp-binding protein
KTC41_RS12765	COG3530	Putative quorum-sensing-regulated virulence factor
KTC41_RS12780	COG0814	amino acid
KTC41_RS12785	COG0242	peptide deformylase activity
KTC41_RS12805	COG2271	Major facilitator Superfamily
KTC41_RS12810	COG0584	glycerophosphoryl diester phosphodiesterase
KTC41_RS12830	COG1609	Transcriptional regulator
KTC41_RS12835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KTC41_RS12840	COG1879	ABC-type sugar transport system periplasmic component
KTC41_RS12845	COG1172	Belongs to the binding-protein-dependent transport system permease family
KTC41_RS12850	COG1129	ABC transporter
KTC41_RS12855	COG1869	D-ribose catabolic process
KTC41_RS12875	COG3501	Rhs element vgr protein
KTC41_RS12875	COG3409	Peptidoglycan-binding domain 1 protein
KTC41_RS12900	COG3829	transcription factor binding
KTC41_RS12965	COG0564	pseudouridine synthase activity
KTC41_RS12975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KTC41_RS12980	COG2771	luxR family
KTC41_RS12980	COG2200	EAL domain
KTC41_RS12990	COG0673	inositol 2-dehydrogenase activity
KTC41_RS12995	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KTC41_RS13030	COG1301	dicarboxylic acid transport
KTC41_RS13035	COG0700	Nucleoside recognition
KTC41_RS13040	COG3366	ferrous iron transmembrane transporter activity
KTC41_RS13045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KTC41_RS13050	COG4565	transcriptional regulatory protein
KTC41_RS13060	COG0471	metal ion transport
KTC41_RS13070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KTC41_RS13075	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KTC41_RS13080	COG2259	Doxx family
KTC41_RS13105	COG0363	glucosamine-6-phosphate deaminase activity
KTC41_RS13110	COG3385	transposase activity
KTC41_RS13125	COG4580	involved in the transport of maltose and maltodextrins
KTC41_RS13140	COG0840	transmembrane signaling receptor activity
KTC41_RS13155	COG0513	Belongs to the DEAD box helicase family
KTC41_RS13165	COG1132	(ABC) transporter
KTC41_RS13175	COG1902	pentaerythritol trinitrate reductase activity
KTC41_RS13185	COG1280	lysine exporter protein (LysE YggA)
KTC41_RS13190	COG2207	Transcriptional regulator
KTC41_RS13220	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KTC41_RS13225	COG0697	spore germination
KTC41_RS13240	COG1073	alpha beta
KTC41_RS13245	COG2814	Major facilitator Superfamily
KTC41_RS13250	COG0583	DNA-binding transcription factor activity
KTC41_RS13255	COG3300	MHYT domain
KTC41_RS13255	COG5001	Diguanylate cyclase
KTC41_RS13260	COG0739	heme binding
KTC41_RS13270	COG0659	secondary active sulfate transmembrane transporter activity
KTC41_RS13275	COG3314	Sporulation integral membrane protein YlbJ
KTC41_RS13290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KTC41_RS13295	COG0581	inorganic phosphate transmembrane transporter activity
KTC41_RS13300	COG0573	inorganic phosphate transmembrane transporter activity
KTC41_RS13305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KTC41_RS13315	COG0513	Belongs to the DEAD box helicase family
KTC41_RS13325	COG1376	ErfK ybiS ycfS ynhG family protein
KTC41_RS13325	COG1388	LysM domain
KTC41_RS13330	COG0415	Belongs to the DNA photolyase family
KTC41_RS13340	COG3272	Protein of unknown function (DUF1722)
KTC41_RS13345	COG0813	purine-nucleoside phosphorylase activity
KTC41_RS13375	COG0786	glutamate:sodium symporter activity
KTC41_RS13390	COG1999	signal sequence binding
KTC41_RS13400	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KTC41_RS13405	COG0671	phosphoesterase, PA-phosphatase related
KTC41_RS13440	COG0471	metal ion transport
KTC41_RS13480	COG4104	PAAR repeat-containing protein
KTC41_RS13485	COG3501	Rhs element vgr protein
KTC41_RS13495	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KTC41_RS13500	COG1640	4-alpha-glucanotransferase
KTC41_RS13505	COG0058	SHG alpha-glucan phosphorylase activity
KTC41_RS13510	COG2909	trisaccharide binding
KTC41_RS13525	COG2084	Dehydrogenase
KTC41_RS13530	COG0217	transcriptional regulatory protein
KTC41_RS13545	COG0444	Belongs to the ABC transporter superfamily
KTC41_RS13550	COG4608	Belongs to the ABC transporter superfamily
KTC41_RS13575	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KTC41_RS13580	COG1444	tRNA N-acetyltransferase activity
KTC41_RS13615	COG0642	Histidine kinase
KTC41_RS13625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KTC41_RS13630	COG0601	transmembrane transport
KTC41_RS13650	COG2198	Histidine kinase
KTC41_RS13650	COG0643	Histidine kinase
KTC41_RS13655	COG0835	chemotaxis
KTC41_RS13660	COG0835	chemotaxis
KTC41_RS13665	COG0840	transmembrane signaling receptor activity
KTC41_RS13670	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KTC41_RS13695	COG0745	RESPONSE REGULATOR receiver
KTC41_RS13700	COG0434	BtpA family
KTC41_RS13705	COG1879	ABC-type sugar transport system periplasmic component
KTC41_RS13710	COG1129	ABC transporter
KTC41_RS13715	COG1172	Belongs to the binding-protein-dependent transport system permease family
KTC41_RS13730	COG1070	Carbohydrate kinase
KTC41_RS13735	COG1349	DNA-binding transcription factor activity
KTC41_RS13775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KTC41_RS13800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KTC41_RS13860	COG1982	Orn Lys Arg decarboxylase major
KTC41_RS13865	COG0531	amino acid
KTC41_RS13880	COG1901	pseudouridine methyltransferase
KTC41_RS13890	COG4221	oxidoreductase activity
KTC41_RS13905	COG2910	NAD(P)H-binding
KTC41_RS13920	COG0697	spore germination
KTC41_RS13950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KTC41_RS13955	COG4597	amino acid ABC transporter
KTC41_RS13960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KTC41_RS13970	COG1126	abc transporter atp-binding protein
KTC41_RS13975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KTC41_RS13985	COG0840	transmembrane signaling receptor activity
KTC41_RS13995	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KTC41_RS14010	COG1620	l-lactate permease
KTC41_RS14020	COG0583	DNA-binding transcription factor activity
KTC41_RS14025	COG4172	Belongs to the ABC transporter superfamily
KTC41_RS14035	COG1067	ATP-dependent peptidase activity
KTC41_RS14045	COG2211	Major facilitator Superfamily
KTC41_RS14055	COG3123	guanosine phosphorylase activity
KTC41_RS14060	COG1741	Belongs to the pirin family
KTC41_RS14070	COG5001	Diguanylate cyclase
KTC41_RS14075	COG0583	DNA-binding transcription factor activity
KTC41_RS14110	COG3706	GGDEF domain
KTC41_RS14120	COG0835	chemotaxis
KTC41_RS14120	COG0784	Response regulator, receiver
KTC41_RS14125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KTC41_RS14135	COG0393	Putative heavy-metal-binding
KTC41_RS14150	COG3842	ATPase activity
KTC41_RS14160	COG1175	transmembrane transport
KTC41_RS14165	COG3833	ABC-type maltose transport systems, permease component
KTC41_RS14180	COG1349	DNA-binding transcription factor activity
KTC41_RS14185	COG2199	diguanylate cyclase activity
KTC41_RS14205	COG1278	Cold shock
KTC41_RS14210	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KTC41_RS14215	COG2354	Protein conserved in bacteria
KTC41_RS14220	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KTC41_RS14225	COG0418	dihydroorotase activity
KTC41_RS14230	COG3217	Mosc domain protein beta barrel domain protein
KTC41_RS14230	COG3217	Mosc domain protein beta barrel domain protein
KTC41_RS14230	COG0633	Ferredoxin
KTC41_RS14230	COG0633	Ferredoxin
KTC41_RS14265	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KTC41_RS14270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KTC41_RS14275	COG4558	Periplasmic binding protein
KTC41_RS14280	COG0848	biopolymer transport protein
KTC41_RS14285	COG0811	peptide transport
KTC41_RS14290	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KTC41_RS14300	COG3721	Heme iron utilization protein
KTC41_RS14305	COG0748	coenzyme F420 binding
KTC41_RS14315	COG3835	regulator
KTC41_RS14320	COG2610	gluconate transmembrane transporter activity
KTC41_RS14325	COG1929	Belongs to the glycerate kinase type-1 family
KTC41_RS14340	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KTC41_RS14345	COG0363	glucosamine-6-phosphate deaminase activity
KTC41_RS14350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KTC41_RS14355	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KTC41_RS14375	COG0346	lactoylglutathione lyase activity
KTC41_RS14385	COG2873	o-acetylhomoserine
KTC41_RS14395	COG1063	alcohol dehydrogenase
KTC41_RS14420	COG0582	viral genome integration into host DNA
KTC41_RS14450	COG1802	Transcriptional regulator
KTC41_RS14450	COG4626	Terminase
KTC41_RS14475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KTC41_RS14480	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KTC41_RS14505	COG0640	Transcriptional regulator
KTC41_RS14510	COG0798	PFAM Bile acid sodium symporter
KTC41_RS14695	COG1278	Cold shock
KTC41_RS14700	COG1686	Belongs to the peptidase S11 family
KTC41_RS14720	COG0366	Alpha amylase catalytic
KTC41_RS14725	COG4989	oxidoreductase activity
KTC41_RS14745	COG0531	amino acid
KTC41_RS14770	COG1765	OsmC-like protein
KTC41_RS14775	COG1253	flavin adenine dinucleotide binding
KTC41_RS14795	COG2264	protein methyltransferase activity
KTC41_RS14810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KTC41_RS14815	COG3186	Phenylalanine-4-hydroxylase
KTC41_RS14820	COG2154	pterin-4-alpha-carbinolamine dehydratase
KTC41_RS14825	COG2239	Acts as a magnesium transporter
KTC41_RS14835	COG1166	arginine decarboxylase activity
KTC41_RS14840	COG0010	Belongs to the arginase family
KTC41_RS14845	COG3706	GGDEF domain
KTC41_RS14860	COG1686	Belongs to the peptidase S11 family
KTC41_RS14875	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KTC41_RS14875	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KTC41_RS14880	COG0509	glycine decarboxylation via glycine cleavage system
KTC41_RS14885	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KTC41_RS14895	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KTC41_RS14910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KTC41_RS14915	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KTC41_RS14995	COG3549	Plasmid maintenance system killer
KTC41_RS15000	COG3093	addiction module antidote protein HigA
KTC41_RS15015	COG2801	Transposase and inactivated derivatives
KTC41_RS15115	COG0110	maltose O-acetyltransferase activity
KTC41_RS15125	COG2801	Transposase and inactivated derivatives
KTC41_RS15175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KTC41_RS15300	COG3549	Plasmid maintenance system killer
KTC41_RS15305	COG3093	addiction module antidote protein HigA
KTC41_RS15350	COG0346	lactoylglutathione lyase activity
KTC41_RS15525	COG2801	Transposase and inactivated derivatives
KTC41_RS15875	COG5642	Protein of unknown function (DUF2384)
KTC41_RS15900	COG2801	Transposase and inactivated derivatives
KTC41_RS15930	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KTC41_RS15935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KTC41_RS15935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KTC41_RS15935	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KTC41_RS15940	COG1105	Belongs to the carbohydrate kinase PfkB family
KTC41_RS15945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KTC41_RS15945	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KTC41_RS15950	COG1609	Transcriptional regulator
KTC41_RS15955	COG0420	3'-5' exonuclease activity
KTC41_RS15960	COG0419	ATPase involved in DNA repair
KTC41_RS15965	COG0784	Response regulator, receiver
KTC41_RS15965	COG2205	protein histidine kinase activity
KTC41_RS15970	COG0156	8-amino-7-oxononanoate synthase activity
KTC41_RS15980	COG0038	chloride channel
KTC41_RS15985	COG0523	cobalamin synthesis protein
KTC41_RS16000	COG2200	EAL domain
KTC41_RS16010	COG3038	cytochrome b561
KTC41_RS16020	COG2116	formate transmembrane transporter activity
KTC41_RS16025	COG0583	DNA-binding transcription factor activity
KTC41_RS16035	COG3593	DNA synthesis involved in DNA repair
KTC41_RS16040	COG0737	Belongs to the 5'-nucleotidase family
KTC41_RS16045	COG0861	Integral membrane protein TerC family
KTC41_RS16055	COG2824	Alkylphosphonate utilization operon protein PhnA
KTC41_RS16100	COG3706	GGDEF domain
KTC41_RS16115	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KTC41_RS16120	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KTC41_RS16130	COG0745	RESPONSE REGULATOR receiver
KTC41_RS16145	COG3140	Belongs to the UPF0181 family
KTC41_RS16205	COG0023	Translation Initiation Factor
KTC41_RS16225	COG0045	succinate-CoA ligase (ADP-forming) activity
KTC41_RS16225	COG1042	CoA-binding domain protein
KTC41_RS16225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KTC41_RS16230	COG0583	DNA-binding transcription factor activity
KTC41_RS16235	COG4771	TonB-dependent receptor
KTC41_RS16250	COG2050	protein possibly involved in aromatic compounds catabolism
KTC41_RS16270	COG0625	glutathione transferase activity
KTC41_RS16285	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KTC41_RS16290	COG4172	Belongs to the ABC transporter superfamily
KTC41_RS16295	COG4239	(ABC) transporter, permease
KTC41_RS16300	COG4174	ABC transporter (Permease)
KTC41_RS16305	COG4166	transmembrane transport
KTC41_RS16330	COG3104	oligopeptide transport
KTC41_RS16350	COG3842	ATPase activity
KTC41_RS16360	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KTC41_RS16365	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KTC41_RS16370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KTC41_RS16375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KTC41_RS16380	COG1011	Hydrolase
KTC41_RS16385	COG1970	mechanosensitive ion channel activity
KTC41_RS16390	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KTC41_RS16395	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KTC41_RS16395	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KTC41_RS16400	COG0302	gtp cyclohydrolase
KTC41_RS16410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KTC41_RS16420	COG2897	thiosulfate sulfurtransferase activity
KTC41_RS16425	COG2390	Transcriptional regulator
KTC41_RS16435	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KTC41_RS16460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KTC41_RS16485	COG0583	DNA-binding transcription factor activity
KTC41_RS16490	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KTC41_RS16535	COG0189	ligase activity
KTC41_RS16535	COG4067	protein conserved in archaea
KTC41_RS16545	COG0602	queuosine metabolic process
KTC41_RS16550	COG1328	CTP reductase activity
KTC41_RS16600	COG0745	RESPONSE REGULATOR receiver
KTC41_RS16605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KTC41_RS16615	COG0545	Peptidyl-prolyl cis-trans isomerase
KTC41_RS16620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KTC41_RS16625	COG0840	transmembrane signaling receptor activity
KTC41_RS16630	COG3069	C4-dicarboxylate transmembrane transporter activity
KTC41_RS16635	COG1760	l-serine dehydratase
KTC41_RS16640	COG2197	response regulator
KTC41_RS16645	COG3850	Histidine kinase
KTC41_RS16650	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KTC41_RS16660	COG0243	molybdopterin cofactor binding
KTC41_RS16680	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KTC41_RS16685	COG3243	poly(R)-hydroxyalkanoic acid synthase
KTC41_RS16695	COG0183	Belongs to the thiolase family
KTC41_RS16705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KTC41_RS16710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KTC41_RS16730	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KTC41_RS16740	COG1979	alcohol dehydrogenase
KTC41_RS16755	COG4191	Histidine kinase
KTC41_RS16765	COG2271	Major facilitator Superfamily
KTC41_RS16770	COG0469	pyruvate kinase activity
KTC41_RS16775	COG2205	protein histidine kinase activity
KTC41_RS16775	COG2198	Histidine kinase
KTC41_RS16775	COG0784	Response regulator, receiver
KTC41_RS16780	COG1879	ABC-type sugar transport system periplasmic component
KTC41_RS16785	COG1803	Methylglyoxal synthase
KTC41_RS16790	COG1335	isochorismatase
KTC41_RS16795	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KTC41_RS16800	COG0210	DNA helicase
KTC41_RS16805	COG1289	transmembrane transporter activity
KTC41_RS16835	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KTC41_RS16840	COG4149	molybdate abc transporter
KTC41_RS16845	COG0725	ABC transporter, periplasmic molybdate-binding protein
KTC41_RS16850	COG1492	cobalamin metabolic process
KTC41_RS16870	COG0784	Response regulator, receiver
KTC41_RS16870	COG5002	protein histidine kinase activity
KTC41_RS16875	COG1879	ABC-type sugar transport system periplasmic component
KTC41_RS16885	COG2827	Endonuclease containing a URI domain
KTC41_RS16890	COG3132	Protein of unknown function, DUF480
KTC41_RS16900	COG2926	Belongs to the UPF0265 family
KTC41_RS16915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KTC41_RS16920	COG3118	belongs to the thioredoxin family
KTC41_RS16950	COG0583	DNA-binding transcription factor activity
KTC41_RS16955	COG4160	amino acid transport
KTC41_RS16960	COG4215	(ABC) transporter
KTC41_RS16965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KTC41_RS16970	COG1126	abc transporter atp-binding protein
KTC41_RS16980	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KTC41_RS16990	COG0494	nUDIX hydrolase
KTC41_RS16995	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
KTC41_RS17005	COG1309	transcriptional regulator
KTC41_RS17010	COG0513	Belongs to the DEAD box helicase family
KTC41_RS17015	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
KTC41_RS17020	COG0814	amino acid
KTC41_RS17025	COG0840	transmembrane signaling receptor activity
KTC41_RS17030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KTC41_RS17035	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KTC41_RS17045	COG1984	allophanate hydrolase subunit 2
KTC41_RS17060	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KTC41_RS17065	COG4181	ATPase activity
KTC41_RS17075	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KTC41_RS17080	COG5001	Diguanylate cyclase
KTC41_RS17080	COG1716	ATPase activity
KTC41_RS17090	COG0484	heat shock protein binding
KTC41_RS17105	COG0546	phosphoglycolate phosphatase activity
KTC41_RS17120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KTC41_RS17130	COG0513	Belongs to the DEAD box helicase family
KTC41_RS17145	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KTC41_RS17155	COG3046	protein related to deoxyribodipyrimidine photolyase
KTC41_RS17160	COG3397	chitin binding
KTC41_RS17185	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KTC41_RS17200	COG2149	membrane
KTC41_RS17210	COG1263	PTS System
KTC41_RS17210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KTC41_RS17235	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KTC41_RS17250	COG2207	Transcriptional regulator
KTC41_RS17255	COG4604	ABC transporter, ATP-binding protein
KTC41_RS17260	COG4605	iron ion homeostasis
KTC41_RS17265	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KTC41_RS17280	COG0840	transmembrane signaling receptor activity
KTC41_RS17305	COG2814	Major facilitator Superfamily
KTC41_RS17310	COG1757	Na H antiporter
KTC41_RS17320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KTC41_RS17320	COG4191	Histidine kinase
KTC41_RS17325	COG0784	Response regulator, receiver
KTC41_RS17325	COG3437	response regulator, receiver
KTC41_RS17330	COG0840	transmembrane signaling receptor activity
KTC41_RS17340	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KTC41_RS17345	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KTC41_RS17350	COG0513	Belongs to the DEAD box helicase family
KTC41_RS17355	COG2801	Transposase and inactivated derivatives
KTC41_RS17365	COG0516	GMP reductase activity
KTC41_RS17375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KTC41_RS17385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KTC41_RS17390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KTC41_RS17390	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KTC41_RS17415	COG3036	rescue of stalled ribosome
KTC41_RS17420	COG1278	Cold shock
KTC41_RS17425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KTC41_RS17425	COG1017	nitric oxide dioxygenase activity
KTC41_RS17430	COG3604	Transcriptional regulator
KTC41_RS17440	COG2195	Cleaves the N-terminal amino acid of tripeptides
KTC41_RS17445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KTC41_RS17460	COG0840	transmembrane signaling receptor activity
KTC41_RS17465	COG0714	Associated with various cellular activities
KTC41_RS17485	COG2304	oxidoreductase activity
KTC41_RS17500	COG1278	Cold shock
KTC41_RS17505	COG5001	Diguanylate cyclase
KTC41_RS17505	COG5002	protein histidine kinase activity
KTC41_RS17530	COG3675	Pfam Lipase (class 3)
KTC41_RS17565	COG2197	response regulator
KTC41_RS17790	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KTC41_RS17875	COG0384	phenazine biosynthesis protein PhzF
KTC41_RS17885	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A