locus-tag	class	description
GPY24_RS00020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY24_RS00030	COG0581	inorganic phosphate transmembrane transporter activity
GPY24_RS00050	COG2304	oxidoreductase activity
GPY24_RS00070	COG0714	Associated with various cellular activities
GPY24_RS00120	COG2207	Transcriptional regulator
GPY24_RS00120	COG4753	response regulator
GPY24_RS00130	COG2354	Protein conserved in bacteria
GPY24_RS00135	COG3706	GGDEF domain
GPY24_RS00140	COG0418	dihydroorotase activity
GPY24_RS00145	COG0633	Ferredoxin
GPY24_RS00145	COG3217	Mosc domain protein beta barrel domain protein
GPY24_RS00145	COG0633	Ferredoxin
GPY24_RS00145	COG3217	Mosc domain protein beta barrel domain protein
GPY24_RS00190	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GPY24_RS00195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY24_RS00205	COG0848	biopolymer transport protein
GPY24_RS00210	COG0811	peptide transport
GPY24_RS00225	COG3721	Heme iron utilization protein
GPY24_RS00230	COG0748	coenzyme F420 binding
GPY24_RS00245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY24_RS00310	COG0583	DNA-binding transcription factor activity
GPY24_RS00315	COG2814	Major facilitator Superfamily
GPY24_RS00330	COG0697	spore germination
GPY24_RS00340	COG1764	response to oxidative stress
GPY24_RS00345	COG1846	Transcriptional regulator
GPY24_RS00395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY24_RS00410	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GPY24_RS00415	COG0513	Belongs to the DEAD box helicase family
GPY24_RS00430	COG1396	sequence-specific DNA binding
GPY24_RS00435	COG3135	benzoate transporter
GPY24_RS00490	COG4175	Glycine betaine
GPY24_RS00495	COG1858	cytochrome C peroxidase
GPY24_RS00510	COG1716	ATPase activity
GPY24_RS00510	COG5001	Diguanylate cyclase
GPY24_RS00530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPY24_RS00535	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GPY24_RS00555	COG1619	proteins homologs of microcin C7 resistance protein MccF
GPY24_RS00560	COG2133	pyrroloquinoline quinone binding
GPY24_RS00585	COG3344	reverse transcriptase
GPY24_RS00600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY24_RS00605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY24_RS00610	COG3186	Phenylalanine-4-hydroxylase
GPY24_RS00630	COG0814	amino acid
GPY24_RS00640	COG0312	modulator of DNA gyrase
GPY24_RS00645	COG0312	modulator of DNA gyrase
GPY24_RS00655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GPY24_RS00665	COG0531	amino acid
GPY24_RS00680	COG2207	Transcriptional regulator
GPY24_RS00695	COG2130	NADP-dependent
GPY24_RS00700	COG1309	transcriptional regulator
GPY24_RS00710	COG0589	response to stress
GPY24_RS00725	COG4607	ABC-type enterochelin transport system periplasmic component
GPY24_RS00735	COG4605	iron ion homeostasis
GPY24_RS00740	COG4604	ABC transporter, ATP-binding protein
GPY24_RS00745	COG0789	Transcriptional regulator
GPY24_RS00750	COG2207	Transcriptional regulator
GPY24_RS00785	COG1289	transmembrane transporter activity
GPY24_RS00795	COG1803	Methylglyoxal synthase
GPY24_RS00800	COG1803	Methylglyoxal synthase
GPY24_RS00805	COG1879	ABC-type sugar transport system periplasmic component
GPY24_RS00810	COG2205	protein histidine kinase activity
GPY24_RS00810	COG2198	Histidine kinase
GPY24_RS00810	COG0784	Response regulator, receiver
GPY24_RS00815	COG0322	excinuclease ABC activity
GPY24_RS00830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GPY24_RS00880	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GPY24_RS00955	COG4172	Belongs to the ABC transporter superfamily
GPY24_RS01020	COG0840	transmembrane signaling receptor activity
GPY24_RS01040	COG0811	peptide transport
GPY24_RS01060	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPY24_RS01065	COG0840	transmembrane signaling receptor activity
GPY24_RS01090	COG2814	Major facilitator Superfamily
GPY24_RS01095	COG3118	belongs to the thioredoxin family
GPY24_RS01100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY24_RS01145	COG1328	CTP reductase activity
GPY24_RS01150	COG0602	queuosine metabolic process
GPY24_RS01160	COG0189	ligase activity
GPY24_RS01160	COG4067	protein conserved in archaea
GPY24_RS01180	COG0725	ABC transporter, periplasmic molybdate-binding protein
GPY24_RS01185	COG4149	molybdate abc transporter
GPY24_RS01200	COG3706	GGDEF domain
GPY24_RS01225	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GPY24_RS01235	COG0745	RESPONSE REGULATOR receiver
GPY24_RS01255	COG0023	Translation Initiation Factor
GPY24_RS01280	COG1042	CoA-binding domain protein
GPY24_RS01280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY24_RS01280	COG0045	succinate-CoA ligase (ADP-forming) activity
GPY24_RS01320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GPY24_RS01330	COG1984	allophanate hydrolase subunit 2
GPY24_RS01335	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GPY24_RS01335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY24_RS01345	COG4181	ATPase activity
GPY24_RS01385	COG1324	tolerance protein
GPY24_RS01395	COG0366	Alpha amylase catalytic
GPY24_RS01400	COG4533	DNA binding
GPY24_RS01410	COG2050	protein possibly involved in aromatic compounds catabolism
GPY24_RS01470	COG0583	DNA-binding transcription factor activity
GPY24_RS01475	COG2116	formate transmembrane transporter activity
GPY24_RS01485	COG3038	cytochrome b561
GPY24_RS01500	COG0513	Belongs to the DEAD box helicase family
GPY24_RS01510	COG0840	transmembrane signaling receptor activity
GPY24_RS01515	COG0546	phosphoglycolate phosphatase activity
GPY24_RS01530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY24_RS01535	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GPY24_RS01550	COG2207	Transcriptional regulator
GPY24_RS01575	COG1609	Transcriptional regulator
GPY24_RS01580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY24_RS01580	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY24_RS01585	COG1105	Belongs to the carbohydrate kinase PfkB family
GPY24_RS01590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY24_RS01590	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GPY24_RS01590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY24_RS01635	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPY24_RS01670	COG0419	ATPase involved in DNA repair
GPY24_RS01680	COG3706	GGDEF domain
GPY24_RS01715	COG0835	chemotaxis
GPY24_RS01715	COG0784	Response regulator, receiver
GPY24_RS01720	COG1609	Transcriptional regulator
GPY24_RS01725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY24_RS01730	COG1879	ABC-type sugar transport system periplasmic component
GPY24_RS01735	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPY24_RS01760	COG2315	Protein conserved in bacteria
GPY24_RS01800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY24_RS01830	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPY24_RS01865	COG2271	Major facilitator Superfamily
GPY24_RS01870	COG0584	glycerophosphoryl diester phosphodiesterase
GPY24_RS01890	COG1472	Belongs to the glycosyl hydrolase 3 family
GPY24_RS01905	COG4580	involved in the transport of maltose and maltodextrins
GPY24_RS01955	COG4608	Belongs to the ABC transporter superfamily
GPY24_RS01960	COG0444	Belongs to the ABC transporter superfamily
GPY24_RS01965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY24_RS01990	COG0583	DNA-binding transcription factor activity
GPY24_RS02000	COG3706	GGDEF domain
GPY24_RS02005	COG0840	transmembrane signaling receptor activity
GPY24_RS02015	COG3036	rescue of stalled ribosome
GPY24_RS02020	COG1278	Cold shock
GPY24_RS02050	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY24_RS02055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY24_RS02065	COG0840	transmembrane signaling receptor activity
GPY24_RS02075	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY24_RS02085	COG4989	oxidoreductase activity
GPY24_RS02120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY24_RS02125	COG2897	thiosulfate sulfurtransferase activity
GPY24_RS02185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPY24_RS02195	COG3706	GGDEF domain
GPY24_RS02210	COG0513	Belongs to the DEAD box helicase family
GPY24_RS02215	COG0523	cobalamin synthesis protein
GPY24_RS02220	COG2384	SAM-dependent methyltransferase
GPY24_RS02225	COG1902	pentaerythritol trinitrate reductase activity
GPY24_RS02240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY24_RS02250	COG3226	Transcriptional regulator
GPY24_RS02365	COG3530	Putative quorum-sensing-regulated virulence factor
GPY24_RS02390	COG0443	Heat shock 70 kDa protein
GPY24_RS02410	COG3437	response regulator, receiver
GPY24_RS02410	COG0784	Response regulator, receiver
GPY24_RS02420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPY24_RS02455	COG0519	Catalyzes the synthesis of GMP from XMP
GPY24_RS02455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GPY24_RS02470	COG2076	Multidrug Resistance protein
GPY24_RS02475	COG0415	Belongs to the DNA photolyase family
GPY24_RS02480	COG0477	Major facilitator Superfamily
GPY24_RS02485	COG0583	DNA-binding transcription factor activity
GPY24_RS02495	COG0840	transmembrane signaling receptor activity
GPY24_RS02515	COG0583	DNA-binding transcription factor activity
GPY24_RS02520	COG1621	beta-fructofuranosidase activity
GPY24_RS02540	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPY24_RS02540	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GPY24_RS02550	COG2201	protein-glutamate methylesterase activity
GPY24_RS02560	COG2197	response regulator
GPY24_RS02580	COG0243	molybdopterin cofactor binding
GPY24_RS02620	COG0183	Belongs to the thiolase family
GPY24_RS02630	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY24_RS02655	COG1522	sequence-specific DNA binding
GPY24_RS02675	COG1879	ABC-type sugar transport system periplasmic component
GPY24_RS02685	COG2827	Endonuclease containing a URI domain
GPY24_RS02725	COG0583	DNA-binding transcription factor activity
GPY24_RS02755	COG0531	amino acid
GPY24_RS02760	COG0121	glutamine amidotransferase
GPY24_RS02765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY24_RS02775	COG2239	Acts as a magnesium transporter
GPY24_RS02790	COG0668	transmembrane transport
GPY24_RS02840	COG3335	DDE superfamily endonuclease
GPY24_RS02885	COG0351	phosphomethylpyrimidine kinase
GPY24_RS02890	COG0671	phosphoesterase, PA-phosphatase related
GPY24_RS02905	COG0561	phosphatase activity
GPY24_RS02920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY24_RS02925	COG0076	glutamate decarboxylase activity
GPY24_RS02940	COG2910	NAD(P)H-binding
GPY24_RS02945	COG0745	RESPONSE REGULATOR receiver
GPY24_RS02955	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPY24_RS02960	COG2194	sulfuric ester hydrolase activity
GPY24_RS02975	COG2356	endonuclease I
GPY24_RS02990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY24_RS03025	COG1309	transcriptional regulator
GPY24_RS03045	COG1301	dicarboxylic acid transport
GPY24_RS03060	COG1335	isochorismatase
GPY24_RS03065	COG4977	sequence-specific DNA binding
GPY24_RS03065	COG1917	Cupin 2, conserved barrel domain protein
GPY24_RS03185	COG2814	Major facilitator Superfamily
GPY24_RS03230	COG0459	protein refolding
GPY24_RS03235	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPY24_RS03260	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPY24_RS03275	COG1278	Cold shock
GPY24_RS03305	COG2865	translation initiation factor activity
GPY24_RS03325	COG0156	8-amino-7-oxononanoate synthase activity
GPY24_RS03345	COG2211	Major facilitator Superfamily
GPY24_RS03365	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPY24_RS03375	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPY24_RS03380	COG0393	Putative heavy-metal-binding
GPY24_RS03395	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY24_RS03430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY24_RS03460	COG2198	Histidine kinase
GPY24_RS03460	COG0643	Histidine kinase
GPY24_RS03475	COG0835	chemotaxis
GPY24_RS03485	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GPY24_RS03490	COG2201	protein-glutamate methylesterase activity
GPY24_RS03505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY24_RS03525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY24_RS03535	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GPY24_RS03545	COG1737	Transcriptional regulator
GPY24_RS03560	COG1131	(ABC) transporter
GPY24_RS03605	COG0513	Belongs to the DEAD box helicase family
GPY24_RS03630	COG3284	Transcriptional regulator
GPY24_RS03660	COG2197	response regulator
GPY24_RS03670	COG4702	Belongs to the UPF0303 family
GPY24_RS03680	COG1349	DNA-binding transcription factor activity
GPY24_RS03685	COG0366	Alpha amylase catalytic
GPY24_RS03695	COG1741	Belongs to the pirin family
GPY24_RS03700	COG2184	nucleotidyltransferase activity
GPY24_RS03715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY24_RS03725	COG3437	response regulator, receiver
GPY24_RS03730	COG2198	Histidine kinase
GPY24_RS03730	COG5002	protein histidine kinase activity
GPY24_RS03730	COG0784	Response regulator, receiver
GPY24_RS03770	COG0745	RESPONSE REGULATOR receiver
GPY24_RS03820	COG0513	Belongs to the DEAD box helicase family
GPY24_RS03840	COG2205	protein histidine kinase activity
GPY24_RS03840	COG0784	Response regulator, receiver
GPY24_RS03840	COG5002	protein histidine kinase activity
GPY24_RS03845	COG3706	GGDEF domain
GPY24_RS03845	COG0745	RESPONSE REGULATOR receiver
GPY24_RS03910	COG0537	adenosine 5'-monophosphoramidase activity
GPY24_RS03925	COG2188	Transcriptional regulator
GPY24_RS03935	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GPY24_RS03955	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPY24_RS03965	COG1132	(ABC) transporter
GPY24_RS04015	COG5001	Diguanylate cyclase
GPY24_RS04025	COG1741	Belongs to the pirin family
GPY24_RS04065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPY24_RS04095	COG0189	ligase activity
GPY24_RS04120	COG0786	glutamate:sodium symporter activity
GPY24_RS04125	COG0786	glutamate:sodium symporter activity
GPY24_RS04135	COG3279	Response regulator of the LytR AlgR family
GPY24_RS04140	COG3275	phosphorelay sensor kinase activity
GPY24_RS04190	COG3227	Zinc metalloprotease (Elastase)
GPY24_RS04210	COG1444	tRNA N-acetyltransferase activity
GPY24_RS04220	COG0215	cysteine-tRNA ligase activity
GPY24_RS04280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY24_RS04300	COG1999	signal sequence binding
GPY24_RS04310	COG1162	GTPase activity
GPY24_RS04320	COG2382	esterase
GPY24_RS04325	COG4771	TonB-dependent receptor
GPY24_RS04355	COG3833	ABC-type maltose transport systems, permease component
GPY24_RS04365	COG2182	Extracellular solute-binding protein
GPY24_RS04375	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY24_RS04385	COG3842	ATPase activity
GPY24_RS04410	COG3210	domain, Protein
GPY24_RS04415	COG2909	trisaccharide binding
GPY24_RS04420	COG0058	SHG alpha-glucan phosphorylase activity
GPY24_RS04425	COG1640	4-alpha-glucanotransferase
GPY24_RS04435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPY24_RS04480	COG2207	Transcriptional regulator
GPY24_RS04480	COG3708	Transcriptional regulator
GPY24_RS04490	COG3384	dioxygenase
GPY24_RS04495	COG0583	DNA-binding transcription factor activity
GPY24_RS04500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY24_RS04505	COG5001	Diguanylate cyclase
GPY24_RS04505	COG4251	negative regulation of phosphorylation
GPY24_RS04505	COG3706	GGDEF domain
GPY24_RS04505	COG2203	Gaf domain
GPY24_RS04510	COG1621	beta-fructofuranosidase activity
GPY24_RS04520	COG1263	PTS System
GPY24_RS04520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY24_RS04525	COG0697	spore germination
GPY24_RS04545	COG0625	glutathione transferase activity
GPY24_RS04550	COG1294	oxidase, subunit
GPY24_RS04555	COG1271	oxidase subunit
GPY24_RS04560	COG0583	DNA-binding transcription factor activity
GPY24_RS04565	COG2814	Major facilitator Superfamily
GPY24_RS04575	COG0583	DNA-binding transcription factor activity
GPY24_RS04600	COG0579	oxidoreductase
GPY24_RS04605	COG1357	PFAM Pentapeptide repeats (8 copies)
GPY24_RS04610	COG3047	cAMP biosynthetic process
GPY24_RS04635	COG0625	glutathione transferase activity
GPY24_RS04640	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPY24_RS04645	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPY24_RS04665	COG3033	Beta-eliminating lyase
GPY24_RS04685	COG0583	DNA-binding transcription factor activity
GPY24_RS04700	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPY24_RS04725	COG1342	Belongs to the UPF0251 family
GPY24_RS04745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY24_RS04750	COG1653	transport
GPY24_RS04755	COG2205	protein histidine kinase activity
GPY24_RS04760	COG0745	RESPONSE REGULATOR receiver
GPY24_RS04780	COG3046	protein related to deoxyribodipyrimidine photolyase
GPY24_RS04795	COG1881	PFAM PEBP family protein
GPY24_RS04830	COG2375	cellular response to nickel ion
GPY24_RS04835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY24_RS04840	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GPY24_RS04865	COG3385	transposase activity
GPY24_RS04880	COG3293	Transposase
GPY24_RS04905	COG3842	ATPase activity
GPY24_RS04935	COG3300	MHYT domain
GPY24_RS04935	COG5001	Diguanylate cyclase
GPY24_RS04945	COG4191	Histidine kinase
GPY24_RS04955	COG2200	EAL domain
GPY24_RS04955	COG2199	diguanylate cyclase activity
GPY24_RS04955	COG2202	Pas domain
GPY24_RS04960	COG3852	Histidine kinase
GPY24_RS04980	COG2188	Transcriptional regulator
GPY24_RS05035	COG1765	OsmC-like protein
GPY24_RS05060	COG1011	Hydrolase
GPY24_RS05065	COG0095	Lipoate-protein ligase
GPY24_RS05070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY24_RS05075	COG2207	Transcriptional regulator
GPY24_RS05075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY24_RS05095	COG3104	oligopeptide transport
GPY24_RS05100	COG1760	l-serine dehydratase
GPY24_RS05115	COG1629	transport
GPY24_RS05130	COG1253	flavin adenine dinucleotide binding
GPY24_RS05140	COG2212	antiporter activity
GPY24_RS05160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GPY24_RS05160	COG2111	Na H antiporter
GPY24_RS05170	COG0589	response to stress
GPY24_RS05175	COG0242	peptide deformylase activity
GPY24_RS05200	COG0745	RESPONSE REGULATOR receiver
GPY24_RS05200	COG3706	GGDEF domain
GPY24_RS05220	COG0745	RESPONSE REGULATOR receiver
GPY24_RS05235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GPY24_RS05250	COG0189	ligase activity
GPY24_RS05250	COG4067	protein conserved in archaea
GPY24_RS05275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY24_RS05310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY24_RS05315	COG1126	abc transporter atp-binding protein
GPY24_RS05320	COG3015	lipoprotein NlpE involved in copper resistance
GPY24_RS05360	COG2814	Major facilitator Superfamily
GPY24_RS05375	COG1304	FMN binding
GPY24_RS05380	COG1620	l-lactate permease
GPY24_RS05385	COG0583	DNA-binding transcription factor activity
GPY24_RS05405	COG1067	ATP-dependent peptidase activity
GPY24_RS05420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY24_RS05435	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPY24_RS05440	COG0583	DNA-binding transcription factor activity
GPY24_RS05445	COG0243	molybdopterin cofactor binding
GPY24_RS05455	COG1122	ATPase activity
GPY24_RS05490	COG0789	Transcriptional regulator
GPY24_RS05500	COG1376	ErfK ybiS ycfS ynhG family protein
GPY24_RS05500	COG1388	LysM domain
GPY24_RS05745	COG0513	Belongs to the DEAD box helicase family
GPY24_RS05765	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
GPY24_RS05770	COG0730	response to heat
GPY24_RS05795	COG0583	DNA-binding transcription factor activity
GPY24_RS05800	COG0640	Transcriptional regulator
GPY24_RS05810	COG0728	peptidoglycan biosynthetic process
GPY24_RS05815	COG0196	riboflavin kinase activity
GPY24_RS05825	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPY24_RS05830	COG1047	Peptidyl-prolyl cis-trans
GPY24_RS05850	COG1966	Carbon starvation protein
GPY24_RS05870	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GPY24_RS05875	COG1472	Belongs to the glycosyl hydrolase 3 family
GPY24_RS05880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY24_RS05915	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GPY24_RS05920	COG0077	Prephenate dehydratase
GPY24_RS05920	COG1605	Chorismate mutase
GPY24_RS05925	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY24_RS05930	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY24_RS05990	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
GPY24_RS05995	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPY24_RS06015	COG5002	protein histidine kinase activity
GPY24_RS06025	COG0248	Ppx GppA phosphatase
GPY24_RS06045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY24_RS06070	COG0583	DNA-binding transcription factor activity
GPY24_RS06075	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GPY24_RS06085	COG0517	IMP dehydrogenase activity
GPY24_RS06095	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPY24_RS06105	COG1862	Preprotein translocase
GPY24_RS06120	COG0483	inositol monophosphate 1-phosphatase activity
GPY24_RS06140	COG0822	iron-sulfur transferase activity
GPY24_RS06145	COG0316	Belongs to the HesB IscA family
GPY24_RS06150	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPY24_RS06155	COG0443	Heat shock 70 kDa protein
GPY24_RS06160	COG0633	Ferredoxin
GPY24_RS06165	COG2975	iron-sulfur cluster assembly
GPY24_RS06210	COG1160	GTP binding
GPY24_RS06215	COG2203	Gaf domain
GPY24_RS06215	COG2199	diguanylate cyclase activity
GPY24_RS06230	COG0516	GMP reductase activity
GPY24_RS06230	COG0517	IMP dehydrogenase activity
GPY24_RS06245	COG1584	GPR1 FUN34 yaaH family protein
GPY24_RS06250	COG0583	DNA-binding transcription factor activity
GPY24_RS06255	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GPY24_RS06270	COG0583	DNA-binding transcription factor activity
GPY24_RS06285	COG0586	Pfam SNARE associated Golgi protein
GPY24_RS06290	COG0009	L-threonylcarbamoyladenylate synthase
GPY24_RS06305	COG0697	spore germination
GPY24_RS06335	COG2867	negative regulation of translational initiation
GPY24_RS06360	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPY24_RS06375	COG0484	heat shock protein binding
GPY24_RS06405	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY24_RS06410	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GPY24_RS06415	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GPY24_RS06420	COG0583	DNA-binding transcription factor activity
GPY24_RS06425	COG0590	tRNA wobble adenosine to inosine editing
GPY24_RS06450	COG3344	reverse transcriptase
GPY24_RS06475	COG2252	PERMEase
GPY24_RS06500	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPY24_RS06505	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPY24_RS06510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY24_RS06510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY24_RS06540	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GPY24_RS06550	COG0142	geranyltranstransferase activity
GPY24_RS06560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPY24_RS06565	COG1360	Flagellar Motor Protein
GPY24_RS06570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY24_RS06570	COG0301	tRNA thio-modification
GPY24_RS06575	COG0583	DNA-binding transcription factor activity
GPY24_RS06600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY24_RS06605	COG1611	Belongs to the LOG family
GPY24_RS06620	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPY24_RS06620	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPY24_RS06630	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GPY24_RS06635	COG1464	Belongs to the NlpA lipoprotein family
GPY24_RS06640	COG2011	ABC-type metal ion transport system permease component
GPY24_RS06650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPY24_RS06660	COG1263	PTS System
GPY24_RS06660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY24_RS06665	COG0366	Alpha amylase catalytic
GPY24_RS06670	COG3344	reverse transcriptase
GPY24_RS06720	COG1686	Belongs to the peptidase S11 family
GPY24_RS06725	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPY24_RS06740	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPY24_RS06745	COG0799	negative regulation of ribosome biogenesis
GPY24_RS06750	COG1466	dna polymerase III delta subunit
GPY24_RS06755	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GPY24_RS06765	COG2888	peptidyl-tyrosine sulfation
GPY24_RS06775	COG4535	Mg2 and Co2 transporter CorC
GPY24_RS06780	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPY24_RS06785	COG1702	phosphate starvation-inducible protein PhoH
GPY24_RS06790	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPY24_RS06795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY24_RS06905	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GPY24_RS06920	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY24_RS06930	COG2912	Transglutaminase-like superfamily
GPY24_RS06935	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GPY24_RS06945	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPY24_RS06950	COG1187	pseudouridine synthase activity
GPY24_RS06985	COG2608	mercury ion transmembrane transporter activity
GPY24_RS06985	COG2217	Heavy metal translocating P-type atpase
GPY24_RS07035	COG0835	chemotaxis
GPY24_RS07035	COG0784	Response regulator, receiver
GPY24_RS07040	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPY24_RS07045	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPY24_RS07050	COG1815	bacterial-type flagellum-dependent cell motility
GPY24_RS07055	COG1558	bacterial-type flagellum-dependent cell motility
GPY24_RS07060	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPY24_RS07070	COG4787	bacterial-type flagellum-dependent cell motility
GPY24_RS07090	COG3951	Flagellar rod assembly protein muramidase FlgJ
GPY24_RS07090	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPY24_RS07100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY24_RS07105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY24_RS07115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY24_RS07120	COG2190	(PTS) system
GPY24_RS07130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY24_RS07135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPY24_RS07140	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GPY24_RS07150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPY24_RS07170	COG0330	HflC and HflK could
GPY24_RS07175	COG3118	belongs to the thioredoxin family
GPY24_RS07185	COG0300	oxidoreductase activity
GPY24_RS07215	COG0622	Phosphoesterase
GPY24_RS07240	COG0326	Molecular chaperone. Has ATPase activity
GPY24_RS07250	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GPY24_RS07265	COG0367	asparagine synthase
GPY24_RS07275	COG1940	carbohydrate kinase activity
GPY24_RS07275	COG1846	Transcriptional regulator
GPY24_RS07285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY24_RS07285	COG2190	(PTS) system
GPY24_RS07285	COG1263	PTS System
GPY24_RS07305	COG0583	DNA-binding transcription factor activity
GPY24_RS07310	COG1380	Effector of murein hydrolase LrgA
GPY24_RS07320	COG0716	FMN binding
GPY24_RS07330	COG0596	Alpha beta hydrolase
GPY24_RS07360	COG2009	succinate dehydrogenase
GPY24_RS07365	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GPY24_RS07370	COG1053	succinate dehydrogenase
GPY24_RS07380	COG0567	Dehydrogenase, E1 component
GPY24_RS07385	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY24_RS07400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPY24_RS07410	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GPY24_RS07420	COG1918	ferrous iron import across plasma membrane
GPY24_RS07425	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GPY24_RS07445	COG3102	Protein conserved in bacteria
GPY24_RS07450	COG0788	formyltetrahydrofolate deformylase activity
GPY24_RS07465	COG1214	PFAM Peptidase M22, glycoprotease
GPY24_RS07475	COG3065	identical protein binding
GPY24_RS07480	COG2267	carboxylic ester hydrolase activity
GPY24_RS07485	COG0318	PFAM AMP-dependent synthetase and ligase
GPY24_RS07500	COG2894	cell division
GPY24_RS07510	COG3100	YcgL domain-containing protein
GPY24_RS07520	COG0583	DNA-binding transcription factor activity
GPY24_RS07525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY24_RS07550	COG0745	RESPONSE REGULATOR receiver
GPY24_RS07555	COG2205	protein histidine kinase activity
GPY24_RS07570	COG0395	ABC-type sugar transport system, permease component
GPY24_RS07580	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPY24_RS07585	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GPY24_RS07590	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GPY24_RS07630	COG0776	regulation of translation
GPY24_RS07635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY24_RS07660	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GPY24_RS07670	COG1169	isochorismate synthase
GPY24_RS07675	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GPY24_RS07680	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPY24_RS07700	COG0477	Major facilitator Superfamily
GPY24_RS07740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY24_RS07755	COG1522	sequence-specific DNA binding
GPY24_RS07760	COG1946	Acyl-CoA thioesterase
GPY24_RS07780	COG2203	Gaf domain
GPY24_RS07780	COG2199	diguanylate cyclase activity
GPY24_RS07855	COG1595	DNA-templated transcription, initiation
GPY24_RS07865	COG3220	belongs to the UPF0276 family
GPY24_RS07890	COG2199	diguanylate cyclase activity
GPY24_RS07890	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPY24_RS07900	COG0659	secondary active sulfate transmembrane transporter activity
GPY24_RS07905	COG5001	Diguanylate cyclase
GPY24_RS07910	COG2205	protein histidine kinase activity
GPY24_RS07915	COG0745	RESPONSE REGULATOR receiver
GPY24_RS07925	COG0569	domain protein
GPY24_RS08015	COG0861	Integral membrane protein TerC family
GPY24_RS08020	COG4584	PFAM Integrase catalytic
GPY24_RS08030	COG0861	Integral membrane protein TerC family
GPY24_RS08040	COG2207	Transcriptional regulator
GPY24_RS08100	COG4935	Belongs to the peptidase S8 family
GPY24_RS08100	COG1404	Belongs to the peptidase S8 family
GPY24_RS08120	COG0516	GMP reductase activity
GPY24_RS08120	COG0517	IMP dehydrogenase activity
GPY24_RS08145	COG0537	adenosine 5'-monophosphoramidase activity
GPY24_RS08175	COG1252	NADH dehydrogenase
GPY24_RS08195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPY24_RS08205	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPY24_RS08210	COG1136	(ABC) transporter
GPY24_RS08215	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPY24_RS08225	COG0658	competence protein
GPY24_RS08225	COG2333	competence protein COMEC
GPY24_RS08230	COG1132	(ABC) transporter
GPY24_RS08245	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GPY24_RS08255	COG2718	Belongs to the UPF0229 family
GPY24_RS08275	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY24_RS08290	COG1882	Formate acetyltransferase
GPY24_RS08320	COG4215	(ABC) transporter
GPY24_RS08325	COG4160	amino acid transport
GPY24_RS08340	COG0840	transmembrane signaling receptor activity
GPY24_RS08350	COG3923	Primosomal replication protein n
GPY24_RS08365	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPY24_RS08385	COG1278	Cold shock
GPY24_RS08400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPY24_RS08405	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GPY24_RS08420	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GPY24_RS08430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY24_RS08435	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPY24_RS08440	COG0297	glycogen (starch) synthase activity
GPY24_RS08460	COG3070	regulator of competence-specific genes
GPY24_RS08470	COG3381	protein complex oligomerization
GPY24_RS08475	COG0745	RESPONSE REGULATOR receiver
GPY24_RS08480	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPY24_RS08485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY24_RS08520	COG4067	protein conserved in archaea
GPY24_RS08520	COG0189	ligase activity
GPY24_RS08535	COG1801	Protein of unknown function DUF72
GPY24_RS08550	COG0840	transmembrane signaling receptor activity
GPY24_RS08560	COG2255	four-way junction helicase activity
GPY24_RS08565	COG1271	oxidase subunit
GPY24_RS08570	COG1294	oxidase, subunit
GPY24_RS08575	COG4890	Cyd operon protein YbgT
GPY24_RS08585	COG0824	Thioesterase
GPY24_RS08605	COG0823	Involved in the tonB-independent uptake of proteins
GPY24_RS08610	COG2885	chlorophyll binding
GPY24_RS08615	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GPY24_RS08625	COG0137	argininosuccinate synthase activity
GPY24_RS08630	COG3766	membrane
GPY24_RS08640	COG0754	glutathionylspermidine amidase activity
GPY24_RS08655	COG1858	cytochrome C peroxidase
GPY24_RS08675	COG5002	protein histidine kinase activity
GPY24_RS08675	COG0784	Response regulator, receiver
GPY24_RS08720	COG1518	maintenance of DNA repeat elements
GPY24_RS08720	COG1468	defense response to virus
GPY24_RS08890	COG2271	Major facilitator Superfamily
GPY24_RS08895	COG3851	Histidine kinase
GPY24_RS08900	COG2197	response regulator
GPY24_RS08910	COG1858	cytochrome C peroxidase
GPY24_RS09030	COG2199	diguanylate cyclase activity
GPY24_RS09030	COG2203	Gaf domain
GPY24_RS09055	COG3706	GGDEF domain
GPY24_RS09150	COG1607	acyl-coa hydrolase
GPY24_RS09165	COG1301	dicarboxylic acid transport
GPY24_RS09170	COG0159	tryptophan synthase activity
GPY24_RS09180	COG0135	phosphoribosylanthranilate isomerase activity
GPY24_RS09180	COG0134	indole-3-glycerol-phosphate synthase activity
GPY24_RS09185	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPY24_RS09190	COG0512	Glutamine amidotransferase of anthranilate synthase
GPY24_RS09195	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY24_RS09205	COG0613	PHP domain protein
GPY24_RS09210	COG0009	L-threonylcarbamoyladenylate synthase
GPY24_RS09235	COG5001	Diguanylate cyclase
GPY24_RS09235	COG3300	MHYT domain
GPY24_RS09245	COG2197	response regulator
GPY24_RS09250	COG0322	excinuclease ABC activity
GPY24_RS09315	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY24_RS09320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY24_RS09340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY24_RS09370	COG3108	Peptidase M15
GPY24_RS09375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY24_RS09390	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPY24_RS09415	COG1846	Transcriptional regulator
GPY24_RS09445	COG1448	Aminotransferase
GPY24_RS09460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY24_RS09480	COG0720	synthase
GPY24_RS09490	COG0577	efflux transmembrane transporter activity
GPY24_RS09490	COG1136	(ABC) transporter
GPY24_RS09500	COG1760	l-serine dehydratase
GPY24_RS09505	COG0814	amino acid
GPY24_RS09535	COG3768	UPF0283 membrane protein
GPY24_RS09540	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GPY24_RS09545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY24_RS09565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY24_RS09565	COG4191	Histidine kinase
GPY24_RS09570	COG2204	response regulator
GPY24_RS09600	COG1328	CTP reductase activity
GPY24_RS09605	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY24_RS09630	COG0814	amino acid
GPY24_RS09640	COG0783	Belongs to the Dps family
GPY24_RS09655	COG1132	(ABC) transporter
GPY24_RS09660	COG1132	(ABC) transporter
GPY24_RS09680	COG3568	Endonuclease Exonuclease Phosphatase
GPY24_RS09705	COG1280	lysine exporter protein (LysE YggA)
GPY24_RS09715	COG0443	Heat shock 70 kDa protein
GPY24_RS09755	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPY24_RS09785	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPY24_RS09795	COG2814	Major facilitator Superfamily
GPY24_RS09800	COG0010	Belongs to the arginase family
GPY24_RS09825	COG4977	sequence-specific DNA binding
GPY24_RS09830	COG1454	alcohol dehydrogenase
GPY24_RS09835	COG0235	Class ii aldolase
GPY24_RS09840	COG3254	rhamnose metabolic process
GPY24_RS09850	COG4806	L-rhamnose isomerase
GPY24_RS09855	COG1070	Carbohydrate kinase
GPY24_RS09860	COG3344	reverse transcriptase
GPY24_RS09895	COG3706	GGDEF domain
GPY24_RS09895	COG0745	RESPONSE REGULATOR receiver
GPY24_RS09915	COG3188	usher protein
GPY24_RS09925	COG3539	Fimbrial protein
GPY24_RS09960	COG2200	EAL domain
GPY24_RS10005	COG1346	cytolysis
GPY24_RS10010	COG1380	Effector of murein hydrolase LrgA
GPY24_RS10015	COG2925	Exonuclease
GPY24_RS10030	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GPY24_RS10060	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GPY24_RS10090	COG1451	nucleotide metabolic process
GPY24_RS10105	COG3063	Type IV pilus biogenesis stability protein PilW
GPY24_RS10125	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GPY24_RS10135	COG0625	glutathione transferase activity
GPY24_RS10165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPY24_RS10170	COG2146	nitrite reductase [NAD(P)H] activity
GPY24_RS10185	COG1278	Cold shock
GPY24_RS10200	COG0730	response to heat
GPY24_RS10225	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPY24_RS10240	COG2828	Protein conserved in bacteria
GPY24_RS10260	COG0561	phosphatase activity
GPY24_RS10265	COG0602	queuosine metabolic process
GPY24_RS10270	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPY24_RS10275	COG3706	GGDEF domain
GPY24_RS10315	COG1254	Belongs to the acylphosphatase family
GPY24_RS10320	COG2920	part of a sulfur-relay system
GPY24_RS10325	COG0670	Belongs to the BI1 family
GPY24_RS10330	COG1126	abc transporter atp-binding protein
GPY24_RS10335	COG0765	amino acid transport
GPY24_RS10340	COG4597	amino acid ABC transporter
GPY24_RS10345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY24_RS10360	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY24_RS10385	COG2996	Protein conserved in bacteria
GPY24_RS10395	COG3008	intermembrane lipid transfer
GPY24_RS10400	COG2995	paraquat-inducible protein a
GPY24_RS10405	COG1132	(ABC) transporter
GPY24_RS10445	COG0167	dihydroorotate dehydrogenase activity
GPY24_RS10455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY24_RS10455	COG0116	Belongs to the methyltransferase superfamily
GPY24_RS10485	COG1067	ATP-dependent peptidase activity
GPY24_RS10490	COG3120	sequence-specific DNA binding
GPY24_RS10525	COG3278	Belongs to the heme-copper respiratory oxidase family
GPY24_RS10540	COG2010	Cytochrome c
GPY24_RS10565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY24_RS10570	COG0589	response to stress
GPY24_RS10585	COG2992	FlgJ-related protein
GPY24_RS10600	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPY24_RS10610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY24_RS10615	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY24_RS10630	COG0488	(ABC) transporter
GPY24_RS10635	COG0746	molybdenum cofactor guanylyltransferase activity
GPY24_RS10640	COG1763	Mo-molybdopterin cofactor biosynthetic process
GPY24_RS10665	COG0840	transmembrane signaling receptor activity
GPY24_RS10670	COG0791	NLP P60 protein
GPY24_RS10670	COG1388	LysM domain
GPY24_RS10680	COG3706	GGDEF domain
GPY24_RS10700	COG0307	riboflavin synthase, alpha
GPY24_RS10705	COG0534	Mate efflux family protein
GPY24_RS10715	COG1793	dna ligase
GPY24_RS10735	COG0584	glycerophosphoryl diester phosphodiesterase
GPY24_RS10740	COG1609	Transcriptional regulator
GPY24_RS10745	COG2723	6-phospho-beta-galactosidase activity
GPY24_RS10750	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GPY24_RS10755	COG1942	4-Oxalocrotonate Tautomerase
GPY24_RS10805	COG1024	Enoyl-CoA hydratase
GPY24_RS10810	COG1960	acyl-CoA dehydrogenase activity
GPY24_RS10820	COG0183	Belongs to the thiolase family
GPY24_RS10830	COG1960	acyl-CoA dehydrogenase activity
GPY24_RS10875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY24_RS10880	COG0640	Transcriptional regulator
GPY24_RS10895	COG0527	aspartate kinase activity
GPY24_RS10900	COG0662	Cupin 2, conserved barrel domain protein
GPY24_RS10905	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPY24_RS10910	COG0456	acetyltransferase
GPY24_RS10920	COG0109	protoheme IX farnesyltransferase activity
GPY24_RS10925	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GPY24_RS10930	COG1845	cytochrome c oxidase, subunit III
GPY24_RS10940	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GPY24_RS10955	COG3437	response regulator, receiver
GPY24_RS10955	COG0784	Response regulator, receiver
GPY24_RS10960	COG0697	spore germination
GPY24_RS10965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY24_RS10995	COG0454	-acetyltransferase
GPY24_RS11070	COG5433	transposase activity
GPY24_RS11085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY24_RS11125	COG1418	mRNA catabolic process
GPY24_RS11135	COG5433	transposase activity
GPY24_RS11225	COG1028	Short-chain dehydrogenase reductase Sdr
GPY24_RS11400	COG4584	PFAM Integrase catalytic
GPY24_RS11600	COG0456	acetyltransferase
GPY24_RS11710	COG2944	sequence-specific DNA binding
GPY24_RS11715	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
GPY24_RS11740	COG4628	conserved protein (DUF2132)
GPY24_RS11775	COG3041	Addiction module toxin RelE StbE family
GPY24_RS12025	COG5433	transposase activity
GPY24_RS12030	COG4584	PFAM Integrase catalytic
GPY24_RS12035	COG1484	DNA-dependent DNA replication
GPY24_RS12130	COG4584	PFAM Integrase catalytic
GPY24_RS12390	COG4584	PFAM Integrase catalytic
GPY24_RS12485	COG0454	-acetyltransferase
GPY24_RS12590	COG5433	transposase activity
GPY24_RS13030	COG4584	PFAM Integrase catalytic
GPY24_RS13145	COG2026	Addiction module toxin, RelE StbE family
GPY24_RS13335	COG3041	Addiction module toxin RelE StbE family
GPY24_RS13445	COG2026	Addiction module toxin, RelE StbE family
GPY24_RS13540	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPY24_RS13545	COG0363	glucosamine-6-phosphate deaminase activity
GPY24_RS13555	COG4565	transcriptional regulatory protein
GPY24_RS13560	COG3290	protein histidine kinase activity
GPY24_RS13575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY24_RS13595	COG1115	amino acid carrier protein
GPY24_RS13605	COG1280	lysine exporter protein (LysE YggA)
GPY24_RS13660	COG0010	Belongs to the arginase family
GPY24_RS13725	COG0398	Pfam SNARE associated Golgi protein
GPY24_RS13730	COG4134	Bacterial extracellular solute-binding protein
GPY24_RS13740	COG4136	ATPase activity
GPY24_RS13745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPY24_RS13755	COG2885	chlorophyll binding
GPY24_RS13795	COG1643	Atp-dependent helicase
GPY24_RS13800	COG0281	malic enzyme
GPY24_RS13805	COG2949	membrane
GPY24_RS13810	COG0471	metal ion transport
GPY24_RS13815	COG3706	GGDEF domain
GPY24_RS13815	COG0745	RESPONSE REGULATOR receiver
GPY24_RS13835	COG0492	ferredoxin-NADP+ reductase activity
GPY24_RS13850	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPY24_RS13860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY24_RS13860	COG4191	Histidine kinase
GPY24_RS13875	COG3070	regulator of competence-specific genes
GPY24_RS13885	COG2431	L-lysine efflux transmembrane transporter activity
GPY24_RS13895	COG0076	glutamate decarboxylase activity
GPY24_RS13900	COG1737	Transcriptional regulator
GPY24_RS13910	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY24_RS13915	COG2985	domain, Protein
GPY24_RS13915	COG3273	potassium ion transport
GPY24_RS13955	COG0534	Mate efflux family protein
GPY24_RS13960	COG0702	epimerase
GPY24_RS13980	COG1061	Type III restriction enzyme res subunit
GPY24_RS13995	COG0642	Histidine kinase
GPY24_RS14005	COG0737	Belongs to the 5'-nucleotidase family
GPY24_RS14015	COG3313	Fe-S protein
GPY24_RS14035	COG0564	pseudouridine synthase activity
GPY24_RS14045	COG3344	reverse transcriptase
GPY24_RS14050	COG3344	reverse transcriptase
GPY24_RS14060	COG0733	neurotransmitter:sodium symporter activity
GPY24_RS14070	COG0626	cystathionine gamma-synthase activity
GPY24_RS14075	COG2818	Glycosylase
GPY24_RS14085	COG1983	PspC domain protein
GPY24_RS14100	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GPY24_RS14110	COG4168	peptide transport system, permease
GPY24_RS14125	COG4172	Belongs to the ABC transporter superfamily
GPY24_RS14160	COG3005	denitrification pathway
GPY24_RS14190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY24_RS14210	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY24_RS14215	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY24_RS14220	COG3012	SEC-C Motif Domain Protein
GPY24_RS14230	COG0741	lytic transglycosylase activity
GPY24_RS14265	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GPY24_RS14265	COG0140	phosphoribosyl-ATP diphosphatase activity
GPY24_RS14275	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPY24_RS14280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPY24_RS14290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPY24_RS14305	COG1757	Na H antiporter
GPY24_RS14310	COG2916	Histone family protein nucleoid-structuring protein H-NS
GPY24_RS14315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY24_RS14325	COG0482	sulfurtransferase activity
GPY24_RS14335	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPY24_RS14345	COG2268	Band 7 protein
GPY24_RS14370	COG1028	Short-chain dehydrogenase reductase Sdr
GPY24_RS14380	COG0501	Belongs to the peptidase M48B family
GPY24_RS14390	COG2226	methyltransferase
GPY24_RS14395	COG0156	8-amino-7-oxononanoate synthase activity
GPY24_RS14430	COG1522	sequence-specific DNA binding
GPY24_RS14435	COG0686	Belongs to the AlaDH PNT family
GPY24_RS14445	COG0583	DNA-binding transcription factor activity
GPY24_RS14475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPY24_RS14860	COG4608	Belongs to the ABC transporter superfamily
GPY24_RS14875	COG4239	(ABC) transporter, permease
GPY24_RS14895	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GPY24_RS14905	COG0539	negative regulation of cytoplasmic translation
GPY24_RS14915	COG0616	signal peptide processing
GPY24_RS14920	COG1028	Short-chain dehydrogenase reductase Sdr
GPY24_RS14930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPY24_RS14935	COG0587	DNA-directed DNA polymerase activity
GPY24_RS14940	COG0784	Response regulator, receiver
GPY24_RS14940	COG0835	chemotaxis
GPY24_RS14945	COG1940	carbohydrate kinase activity
GPY24_RS14950	COG0469	pyruvate kinase activity
GPY24_RS14955	COG4667	esterase of the alpha-beta hydrolase superfamily
GPY24_RS14970	COG0733	neurotransmitter:sodium symporter activity
GPY24_RS14980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY24_RS14980	COG1263	PTS System
GPY24_RS14985	COG0084	hydrolase, TatD family'
GPY24_RS15000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPY24_RS15030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY24_RS15045	COG1399	metal-binding, possibly nucleic acid-binding protein
GPY24_RS15050	COG0424	maF-like protein
GPY24_RS15060	COG1530	ribonuclease E activity
GPY24_RS15065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPY24_RS15070	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GPY24_RS15080	COG0572	uridine kinase
GPY24_RS15090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY24_RS15090	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY24_RS15115	COG0653	protein targeting
GPY24_RS15135	COG4120	Belongs to the binding-protein-dependent transport system permease family
GPY24_RS15145	COG3092	negative regulation of chromosome organization
GPY24_RS15150	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPY24_RS15160	COG3174	membrane
GPY24_RS15165	COG0435	Glutathione S-transferase
GPY24_RS15170	COG3344	reverse transcriptase
GPY24_RS15185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY24_RS15190	COG0601	transmembrane transport
GPY24_RS15205	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPY24_RS15215	COG0521	Mo-molybdopterin cofactor biosynthetic process
GPY24_RS15225	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GPY24_RS15250	COG0668	transmembrane transport
GPY24_RS15255	COG2995	paraquat-inducible protein a
GPY24_RS15260	COG3008	intermembrane lipid transfer
GPY24_RS15260	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPY24_RS15280	COG2814	Major facilitator Superfamily
GPY24_RS15285	COG1566	PFAM secretion protein HlyD family protein
GPY24_RS15295	COG4657	Part of a membrane complex involved in electron transport
GPY24_RS15305	COG4656	Part of a membrane complex involved in electron transport
GPY24_RS15315	COG4659	FMN binding
GPY24_RS15325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPY24_RS15330	COG0346	lactoylglutathione lyase activity
GPY24_RS15340	COG2885	chlorophyll binding
GPY24_RS15345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPY24_RS15350	COG2056	Na+-H+ antiporter family
GPY24_RS15360	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GPY24_RS15390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY24_RS15395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPY24_RS15410	COG3081	Nucleoid-associated protein
GPY24_RS15420	COG3083	sulfuric ester hydrolase activity
GPY24_RS15425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY24_RS15440	COG0123	including yeast histone deacetylase and acetoin utilization protein
GPY24_RS15445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY24_RS15450	COG0778	Nitroreductase
GPY24_RS15455	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPY24_RS15455	COG1902	pentaerythritol trinitrate reductase activity
GPY24_RS15460	COG0616	signal peptide processing
GPY24_RS15465	COG0252	asparaginase activity
GPY24_RS15470	COG3139	Protein of unknown function (DUF1315)
GPY24_RS15485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY24_RS15500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPY24_RS15515	COG2873	o-acetylhomoserine
GPY24_RS15520	COG1285	pathogenesis
GPY24_RS15525	COG2239	Acts as a magnesium transporter
GPY24_RS15570	COG1785	Belongs to the alkaline phosphatase family
GPY24_RS15575	COG2983	Belongs to the UPF0260 family
GPY24_RS15585	COG0745	RESPONSE REGULATOR receiver
GPY24_RS15590	COG2205	protein histidine kinase activity
GPY24_RS15610	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPY24_RS15625	COG2832	Protein of unknown function (DUF454)
GPY24_RS15655	COG1286	toxin biosynthetic process
GPY24_RS15660	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GPY24_RS15695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPY24_RS15715	COG3101	peptidyl-lysine hydroxylation
GPY24_RS15720	COG2860	membrane
GPY24_RS15730	COG0583	DNA-binding transcription factor activity
GPY24_RS15735	COG0583	DNA-binding transcription factor activity
GPY24_RS15740	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPY24_RS15745	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY24_RS15750	COG2840	Smr protein MutS2
GPY24_RS15755	COG2062	phosphohistidine phosphatase, SixA
GPY24_RS15760	COG1025	Belongs to the peptidase M16 family
GPY24_RS15765	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPY24_RS15765	COG1024	Enoyl-CoA hydratase
GPY24_RS15810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY24_RS15815	COG1138	Cytochrome C-type biogenesis protein
GPY24_RS15825	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY24_RS15830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY24_RS15835	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY24_RS15840	COG4133	protoheme IX ABC transporter activity
GPY24_RS15860	COG1192	Involved in chromosome partitioning
GPY24_RS15870	COG0643	Histidine kinase
GPY24_RS15870	COG2198	Histidine kinase
GPY24_RS15875	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GPY24_RS15910	COG1684	flagellar biosynthetic protein fliR
GPY24_RS15915	COG1987	bacterial-type flagellum assembly
GPY24_RS15970	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY24_RS15980	COG1677	Flagellar hook-basal body complex protein FliE
GPY24_RS15985	COG2204	response regulator
GPY24_RS15990	COG4191	Histidine kinase
GPY24_RS15995	COG2204	response regulator
GPY24_RS16000	COG1516	flagellar protein fliS
GPY24_RS16010	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPY24_RS16015	COG1334	flagellar protein FlaG
GPY24_RS16025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY24_RS16030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY24_RS16035	COG2837	iron assimilation
GPY24_RS16065	COG1393	Belongs to the ArsC family
GPY24_RS16070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY24_RS16090	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GPY24_RS16095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPY24_RS16100	COG2716	regulation of RNA biosynthetic process
GPY24_RS16105	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPY24_RS16120	COG4783	chaperone-mediated protein folding
GPY24_RS16125	COG1393	Belongs to the ArsC family
GPY24_RS16145	COG2233	PERMEase
GPY24_RS16150	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPY24_RS16155	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GPY24_RS16165	COG0121	glutamine amidotransferase
GPY24_RS16185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPY24_RS16195	COG2226	methyltransferase
GPY24_RS16200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY24_RS16205	COG1388	LysM domain
GPY24_RS16205	COG0741	lytic transglycosylase activity
GPY24_RS16215	COG3021	interspecies interaction between organisms
GPY24_RS16220	COG0347	Belongs to the P(II) protein family
GPY24_RS16250	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY24_RS16265	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY24_RS16290	COG0575	Belongs to the CDS family
GPY24_RS16300	COG0233	cytoplasmic translational termination
GPY24_RS16320	COG0024	Methionine aminopeptidase
GPY24_RS16325	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GPY24_RS16340	COG3098	single-species biofilm formation
GPY24_RS16370	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY24_RS16375	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GPY24_RS16410	COG0733	neurotransmitter:sodium symporter activity
GPY24_RS16445	COG1477	protein flavinylation
GPY24_RS16450	COG2871	sodium ion transport
GPY24_RS16455	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY24_RS16470	COG1805	sodium ion transport
GPY24_RS16475	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY24_RS16480	COG0271	Belongs to the BolA IbaG family
GPY24_RS16510	COG1595	DNA-templated transcription, initiation
GPY24_RS16520	COG3248	Nucleoside-binding outer membrane protein
GPY24_RS16525	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPY24_RS16535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPY24_RS16540	COG2166	iron-sulfur cluster assembly
GPY24_RS16545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GPY24_RS16550	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GPY24_RS16570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GPY24_RS16575	COG1074	ATP-dependent DNA helicase activity
GPY24_RS16580	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GPY24_RS16585	COG3083	sulfuric ester hydrolase activity
GPY24_RS16600	COG3141	response to X-ray
GPY24_RS16605	COG2171	N-acyltransferase activity
GPY24_RS16620	COG1349	DNA-binding transcription factor activity
GPY24_RS16625	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPY24_RS16635	COG0456	acetyltransferase
GPY24_RS16665	COG0583	DNA-binding transcription factor activity
GPY24_RS16670	COG2059	Chromate
GPY24_RS16685	COG0583	DNA-binding transcription factor activity
GPY24_RS16695	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPY24_RS16705	COG0560	Phosphoserine phosphatase
GPY24_RS16730	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPY24_RS16740	COG0084	hydrolase, TatD family'
GPY24_RS16770	COG3153	acetyltransferase
GPY24_RS16795	COG0534	Mate efflux family protein
GPY24_RS16805	COG4785	May be involved in cell division
GPY24_RS16820	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPY24_RS16830	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPY24_RS16835	COG0195	Participates in both transcription termination and antitermination
GPY24_RS16840	COG0779	Required for maturation of 30S ribosomal subunits
GPY24_RS16855	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY24_RS16865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPY24_RS16870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPY24_RS16880	COG1534	Rna-binding protein
GPY24_RS16885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY24_RS16890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPY24_RS16900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPY24_RS16905	COG0739	heme binding
GPY24_RS16925	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GPY24_RS16935	COG2813	Specifically methylates the guanine in position
GPY24_RS16945	COG0747	negative chemotaxis
GPY24_RS16955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY24_RS16960	COG0444	Belongs to the ABC transporter superfamily
GPY24_RS16975	COG2971	BadF BadG BcrA BcrD
GPY24_RS16990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY24_RS16995	COG3842	ATPase activity
GPY24_RS17015	COG0347	Belongs to the P(II) protein family
GPY24_RS17020	COG4771	TonB-dependent receptor
GPY24_RS17030	COG0745	RESPONSE REGULATOR receiver
GPY24_RS17040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPY24_RS17045	COG1121	(ABC) transporter
GPY24_RS17085	COG3835	regulator
GPY24_RS17090	COG2610	gluconate transmembrane transporter activity
GPY24_RS17095	COG1929	Belongs to the glycerate kinase type-1 family
GPY24_RS17105	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPY24_RS17125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY24_RS17130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY24_RS17140	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY24_RS17155	COG0842	Transport permease protein
GPY24_RS17160	COG1131	(ABC) transporter
GPY24_RS17165	COG0659	secondary active sulfate transmembrane transporter activity
GPY24_RS17170	COG0288	reversible hydration of carbon dioxide
GPY24_RS17185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY24_RS17195	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GPY24_RS17200	COG2186	Transcriptional regulator
GPY24_RS17220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY24_RS17245	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GPY24_RS17250	COG0335	large ribosomal subunit rRNA binding
GPY24_RS17270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPY24_RS17275	COG4137	Cytochrome C assembly protein
GPY24_RS17280	COG4536	flavin adenine dinucleotide binding
GPY24_RS17305	COG1238	metal cluster binding
GPY24_RS17310	COG1063	alcohol dehydrogenase
GPY24_RS17315	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPY24_RS17320	COG0511	ligase activity, forming carbon-carbon bonds
GPY24_RS17320	COG5016	pyruvate
GPY24_RS17380	COG0527	aspartate kinase activity
GPY24_RS17385	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPY24_RS17430	COG0585	pseudouridine synthase activity
GPY24_RS17440	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPY24_RS17460	COG3956	TIGRFAM MazG family protein
GPY24_RS17465	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY24_RS17495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPY24_RS17505	COG0681	Belongs to the peptidase S26 family
GPY24_RS17515	COG3086	response to oxidative stress
GPY24_RS17520	COG3026	antisigma factor binding
GPY24_RS17530	COG1595	DNA-templated transcription, initiation
GPY24_RS17550	COG0354	folic acid binding
GPY24_RS17570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY24_RS17580	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPY24_RS17590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPY24_RS17600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY24_RS17635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY24_RS17640	COG4771	TonB-dependent receptor
GPY24_RS17645	COG0583	DNA-binding transcription factor activity
GPY24_RS17665	COG2356	endonuclease I
GPY24_RS17675	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GPY24_RS17705	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPY24_RS17715	COG0762	integral membrane protein
GPY24_RS17735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY24_RS17750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GPY24_RS17765	COG0741	lytic transglycosylase activity
GPY24_RS17820	COG1012	belongs to the aldehyde dehydrogenase family
GPY24_RS17940	COG0795	lipopolysaccharide-transporting ATPase activity
GPY24_RS17945	COG0795	lipopolysaccharide-transporting ATPase activity
GPY24_RS17955	COG2927	DNA polymerase III (CHI subunit)
GPY24_RS17980	COG0456	acetyltransferase
GPY24_RS18010	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GPY24_RS18015	COG0251	oxidation-reduction process
GPY24_RS18020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY24_RS18035	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GPY24_RS18040	COG0312	modulator of DNA gyrase
GPY24_RS18045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPY24_RS18050	COG3164	Protein of unknown function
GPY24_RS18055	COG1530	ribonuclease E activity
GPY24_RS18065	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GPY24_RS18070	COG1792	Involved in formation and maintenance of cell shape
GPY24_RS18075	COG1077	Cell shape determining protein MreB Mrl
GPY24_RS18130	COG1459	type II secretion system
GPY24_RS18145	COG3267	Type II secretory pathway component ExeA
GPY24_RS18145	COG3409	Peptidoglycan-binding domain 1 protein
GPY24_RS18170	COG2199	diguanylate cyclase activity
GPY24_RS18170	COG2200	EAL domain
GPY24_RS18175	COG0629	single-stranded DNA binding
GPY24_RS18190	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPY24_RS18200	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPY24_RS18220	COG3706	GGDEF domain
GPY24_RS18225	COG3335	DDE superfamily endonuclease
GPY24_RS18290	COG0175	sulfate reduction
GPY24_RS18300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY24_RS18325	COG0735	belongs to the Fur family
GPY24_RS18335	COG0166	Belongs to the GPI family
GPY24_RS18340	COG0432	Pfam Uncharacterised protein family UPF0047
GPY24_RS18350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY24_RS18355	COG0305	Participates in initiation and elongation during chromosome replication
GPY24_RS18380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPY24_RS18385	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GPY24_RS18430	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GPY24_RS18460	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPY24_RS18465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY24_RS18470	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GPY24_RS18480	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPY24_RS18500	COG0281	malic enzyme
GPY24_RS18515	COG0254	rRNA binding
GPY24_RS18520	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPY24_RS18525	COG1609	Transcriptional regulator
GPY24_RS18545	COG1575	Belongs to the MenA family. Type 1 subfamily
GPY24_RS18560	COG1494	fructose-1,6-bisphosphatase
GPY24_RS18590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPY24_RS18605	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GPY24_RS18615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPY24_RS18635	COG3023	N-Acetylmuramoyl-L-alanine amidase
GPY24_RS18655	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GPY24_RS18660	COG0662	Cupin 2, conserved barrel domain protein
GPY24_RS18660	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GPY24_RS18665	COG1051	belongs to the nudix hydrolase family
GPY24_RS18670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY24_RS18680	COG1216	Glycosyl transferase, family 2
GPY24_RS18695	COG5433	transposase activity
GPY24_RS18705	COG5433	transposase activity
GPY24_RS18725	COG1083	cytidylyl-transferase
GPY24_RS18730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GPY24_RS18735	COG1086	Polysaccharide biosynthesis protein
GPY24_RS18755	COG1596	polysaccharide export
GPY24_RS18775	COG1404	Belongs to the peptidase S8 family
GPY24_RS18800	COG1560	Kdo2-lipid A biosynthetic process
GPY24_RS18810	COG1519	Transferase
GPY24_RS18820	COG0110	maltose O-acetyltransferase activity
GPY24_RS18825	COG1028	Short-chain dehydrogenase reductase Sdr
GPY24_RS18865	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GPY24_RS18870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GPY24_RS18885	COG1215	transferase activity, transferring glycosyl groups
GPY24_RS18905	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY24_RS18925	COG3083	sulfuric ester hydrolase activity
GPY24_RS18930	COG3642	lipopolysaccharide core region biosynthetic process
GPY24_RS18935	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPY24_RS18945	COG0463	Glycosyl transferase, family 2
GPY24_RS18950	COG0859	PFAM glycosyl transferase family 9
GPY24_RS18985	COG2003	Belongs to the UPF0758 family
GPY24_RS18990	COG0840	transmembrane signaling receptor activity
GPY24_RS19020	COG1561	YicC-like family, N-terminal region
GPY24_RS19120	COG0724	RNA recognition motif
GPY24_RS19170	COG2937	Belongs to the GPAT DAPAT family
GPY24_RS19180	COG0456	acetyltransferase
GPY24_RS19190	COG1295	ribonuclease BN
GPY24_RS19215	COG3852	Histidine kinase
GPY24_RS19225	COG4251	negative regulation of phosphorylation
GPY24_RS19225	COG3706	GGDEF domain
GPY24_RS19225	COG5001	Diguanylate cyclase
GPY24_RS19225	COG2203	Gaf domain
GPY24_RS19230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY24_RS19280	COG0084	hydrolase, TatD family'
GPY24_RS19285	COG0805	protein transport
GPY24_RS19300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GPY24_RS19335	COG2081	HI0933 family
GPY24_RS19345	COG1528	Iron-storage protein
GPY24_RS19350	COG0589	response to stress
GPY24_RS19370	COG5001	Diguanylate cyclase
GPY24_RS19370	COG5002	protein histidine kinase activity
GPY24_RS19375	COG1522	sequence-specific DNA binding
GPY24_RS19385	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GPY24_RS19405	COG2814	Major facilitator Superfamily
GPY24_RS19410	COG0800	Aldolase
GPY24_RS19415	COG2610	gluconate transmembrane transporter activity
GPY24_RS19420	COG3265	gluconokinase activity
GPY24_RS19425	COG0129	dihydroxy-acid dehydratase activity
GPY24_RS19430	COG1609	Transcriptional regulator
GPY24_RS19445	COG2815	serine threonine protein kinase
GPY24_RS19445	COG0515	serine threonine protein kinase
GPY24_RS19480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY24_RS19490	COG4166	transmembrane transport
GPY24_RS19535	COG1309	transcriptional regulator
GPY24_RS19550	COG2960	long-chain fatty acid transporting porin activity
GPY24_RS19560	COG0583	DNA-binding transcription factor activity
GPY24_RS19585	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GPY24_RS19590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY24_RS19595	COG1739	Uncharacterized protein family UPF0029
GPY24_RS19605	COG0183	Belongs to the thiolase family
GPY24_RS19610	COG0604	alcohol dehydrogenase
GPY24_RS19630	COG0583	DNA-binding transcription factor activity
GPY24_RS19635	COG0655	NAD(P)H dehydrogenase (quinone) activity
GPY24_RS19665	COG4977	sequence-specific DNA binding
GPY24_RS19675	COG2119	membrane
GPY24_RS19685	COG0751	glycine-tRNA ligase activity
GPY24_RS19690	COG3977	Valine--pyruvate aminotransferase
GPY24_RS19695	COG0071	Belongs to the small heat shock protein (HSP20) family
GPY24_RS19710	COG0592	DNA-directed DNA polymerase activity
GPY24_RS19745	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GPY24_RS19765	COG3730	PTS system glucitol sorbitol-specific
GPY24_RS19780	COG1028	Short-chain dehydrogenase reductase Sdr
GPY24_RS19790	COG1349	DNA-binding transcription factor activity
GPY24_RS19795	COG3730	PTS system glucitol sorbitol-specific
GPY24_RS19810	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY24_RS19815	COG0445	tRNA wobble uridine modification
GPY24_RS19820	COG0357	Ribosomal RNA small subunit methyltransferase G
GPY24_RS19825	COG1192	Involved in chromosome partitioning
GPY24_RS19830	COG1475	DNA binding
GPY24_RS19835	COG3312	ion transport
GPY24_RS19865	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPY24_RS19885	COG2814	Major facilitator Superfamily
GPY24_RS19890	COG0583	DNA-binding transcription factor activity
GPY24_RS19905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPY24_RS19910	COG3978	acetolactate synthase activity
GPY24_RS19920	COG0606	chelatase, subunit chli
GPY24_RS19930	COG0204	Acyl-transferase
GPY24_RS19935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY24_RS19950	COG3084	Protein conserved in bacteria
GPY24_RS19955	COG4326	sporulation control protein
GPY24_RS19970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY24_RS19985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPY24_RS20000	COG0758	DNA mediated transformation
GPY24_RS20010	COG0551	DNA topoisomerase type I activity
GPY24_RS20025	COG0009	L-threonylcarbamoyladenylate synthase
GPY24_RS20030	COG0408	coproporphyrinogen oxidase activity
GPY24_RS20035	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPY24_RS20045	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPY24_RS20080	COG3335	DDE superfamily endonuclease
GPY24_RS20100	COG0352	thiamine-phosphate diphosphorylase activity
GPY24_RS20105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY24_RS20120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPY24_RS20155	COG3220	belongs to the UPF0276 family
GPY24_RS20180	COG2962	Rard protein
GPY24_RS20195	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPY24_RS20210	COG3118	belongs to the thioredoxin family
GPY24_RS20215	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPY24_RS20225	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GPY24_RS20275	COG3335	DDE superfamily endonuclease
GPY24_RS20290	COG2959	enzyme of heme biosynthesis
GPY24_RS20295	COG1587	Uroporphyrinogen-III synthase
GPY24_RS20305	COG3072	Adenylate cyclase
GPY24_RS20340	COG1011	Hydrolase
GPY24_RS20370	COG2267	carboxylic ester hydrolase activity
GPY24_RS20375	COG1280	lysine exporter protein (LysE YggA)
GPY24_RS20380	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY24_RS20385	COG3274	enterobacterial common antigen metabolic process
GPY24_RS20405	COG2095	MarC family integral membrane protein
GPY24_RS20415	COG0742	ribosomal rna small subunit methyltransferase
GPY24_RS20425	COG2884	Cell division ATP-binding protein ftsE
GPY24_RS20430	COG2177	Part of the ABC transporter FtsEX involved in
GPY24_RS20445	COG0705	Rhomboid family
GPY24_RS20450	COG1580	Controls the rotational direction of flagella during chemotaxis
GPY24_RS20480	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GPY24_RS20485	COG3031	protein transport across the cell outer membrane
GPY24_RS20495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY24_RS20505	COG2165	general secretion pathway protein
GPY24_RS20510	COG2165	general secretion pathway protein
GPY24_RS20515	COG2165	general secretion pathway protein
GPY24_RS20520	COG4795	General secretion pathway protein
GPY24_RS20525	COG3156	type II secretion system protein K
GPY24_RS20530	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPY24_RS20535	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPY24_RS20550	COG0494	nUDIX hydrolase
GPY24_RS20560	COG1040	competence protein
GPY24_RS20575	COG2183	response to ionizing radiation
GPY24_RS20600	COG2124	cytochrome p450
GPY24_RS20605	COG0477	Major facilitator Superfamily
GPY24_RS20615	COG0745	RESPONSE REGULATOR receiver
GPY24_RS20625	COG2233	PERMEase
GPY24_RS20635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY24_RS20640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY24_RS20645	COG1758	RNA polymerase activity
GPY24_RS20665	COG0848	biopolymer transport protein
GPY24_RS20670	COG0811	peptide transport
GPY24_RS20690	COG4174	ABC transporter (Permease)
GPY24_RS20695	COG4239	(ABC) transporter, permease
GPY24_RS20705	COG0444	Belongs to the ABC transporter superfamily
GPY24_RS20710	COG4608	Belongs to the ABC transporter superfamily
GPY24_RS20725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPY24_RS20790	COG0081	regulation of translation
GPY24_RS20795	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPY24_RS20830	COG1573	uracil-dna glycosylase
GPY24_RS20835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY24_RS20840	COG3068	Protein conserved in bacteria
GPY24_RS20845	COG1253	flavin adenine dinucleotide binding
GPY24_RS20865	COG0138	bifunctional purine biosynthesis protein purh
GPY24_RS20875	COG0789	Transcriptional regulator
GPY24_RS20900	COG2188	Transcriptional regulator
GPY24_RS20925	COG0732	type I restriction modification DNA specificity domain
GPY24_RS20930	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GPY24_RS20960	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GPY24_RS20975	COG0439	Biotin carboxylase
GPY24_RS20980	COG0511	ligase activity, forming carbon-carbon bonds
GPY24_RS20995	COG1902	pentaerythritol trinitrate reductase activity
GPY24_RS21015	COG2814	Major facilitator Superfamily
GPY24_RS21020	COG0784	Response regulator, receiver
GPY24_RS21020	COG2198	Histidine kinase
GPY24_RS21020	COG2205	protein histidine kinase activity
GPY24_RS21025	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY24_RS21035	COG3263	regulation of cellular component size
GPY24_RS21050	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPY24_RS21065	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GPY24_RS21070	COG2205	protein histidine kinase activity
GPY24_RS21075	COG0745	RESPONSE REGULATOR receiver
GPY24_RS21140	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPY24_RS21145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPY24_RS21195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY24_RS21305	COG0802	atpase or kinase
GPY24_RS21330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPY24_RS21335	COG0330	HflC and HflK could
GPY24_RS21340	COG0330	HflC and HflK could
GPY24_RS21345	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GPY24_RS21355	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GPY24_RS21370	COG0557	exoribonuclease II activity
GPY24_RS21400	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPY24_RS21410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPY24_RS21420	COG1012	belongs to the aldehyde dehydrogenase family
GPY24_RS21430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY24_RS21435	COG3954	Phosphoribulokinase
GPY24_RS21445	COG0429	hydrolase of the alpha beta-hydrolase fold
GPY24_RS21455	COG0488	(ABC) transporter
GPY24_RS21460	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPY24_RS21475	COG1047	Peptidyl-prolyl cis-trans
GPY24_RS21500	COG2964	Protein conserved in bacteria
GPY24_RS21510	COG2923	Belongs to the DsrF TusC family
GPY24_RS21540	COG2906	2 iron, 2 sulfur cluster binding
GPY24_RS21555	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPY24_RS21560	COG0088	Forms part of the polypeptide exit tunnel
GPY24_RS21625	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPY24_RS21635	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPY24_RS21645	COG1841	ribosomal large subunit assembly
GPY24_RS21655	COG0201	protein transport
GPY24_RS21670	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPY24_RS21690	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY24_RS21700	COG0697	spore germination
GPY24_RS21720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPY24_RS21720	COG1648	precorrin-2 dehydrogenase activity
GPY24_RS21725	COG0175	sulfate reduction
GPY24_RS21730	COG2895	sulfate adenylyltransferase (ATP) activity
GPY24_RS21735	COG3273	potassium ion transport
GPY24_RS21735	COG0471	metal ion transport
GPY24_RS21760	COG1136	(ABC) transporter
GPY24_RS21760	COG0577	efflux transmembrane transporter activity
GPY24_RS21775	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GPY24_RS21790	COG0729	surface antigen
GPY24_RS21800	COG2105	PFAM AIG2 family protein
GPY24_RS21815	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPY24_RS21820	COG0163	prenyltransferase activity
GPY24_RS21825	COG4143	(ABC) transporter
GPY24_RS21830	COG1178	ABC-type Fe3 transport system permease component
GPY24_RS21840	COG3028	Belongs to the UPF0307 family
GPY24_RS21845	COG0312	modulator of DNA gyrase
GPY24_RS21850	COG2239	Acts as a magnesium transporter
GPY24_RS21855	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY24_RS21860	COG1660	Displays ATPase and GTPase activities
GPY24_RS21870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY24_RS21880	COG1137	ATPase activity
GPY24_RS21895	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GPY24_RS21900	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GPY24_RS21900	COG0517	IMP dehydrogenase activity
GPY24_RS21910	COG1127	ABC transporter
GPY24_RS21915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GPY24_RS21925	COG2854	intermembrane phospholipid transfer
GPY24_RS21935	COG5007	Belongs to the BolA IbaG family
GPY24_RS21940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPY24_RS21945	COG0204	Acyl-transferase
GPY24_RS21950	COG0589	response to stress
GPY24_RS21980	COG0142	geranyltranstransferase activity
GPY24_RS21985	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GPY24_RS22000	COG2966	Psort location CytoplasmicMembrane, score
GPY24_RS22030	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GPY24_RS22075	COG1309	transcriptional regulator
GPY24_RS22095	COG1022	Amp-dependent synthetase and ligase
GPY24_RS22105	COG0440	acetolactate synthase activity
GPY24_RS22115	COG1802	Transcriptional regulator
GPY24_RS22120	COG0469	pyruvate kinase activity
GPY24_RS22125	COG1349	DNA-binding transcription factor activity
GPY24_RS22135	COG3722	fumarate hydratase activity
GPY24_RS22145	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY24_RS22145	COG2213	PTS system mannitol-specific
GPY24_RS22165	COG3550	peptidyl-serine autophosphorylation
GPY24_RS22190	COG1610	YqeY-like protein
GPY24_RS22195	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GPY24_RS22215	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPY24_RS22220	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY24_RS22230	COG0617	tRNA 3'-terminal CCA addition
GPY24_RS22240	COG4991	sh3 domain protein
GPY24_RS22245	COG0306	phosphate transporter
GPY24_RS22250	COG1392	Phosphate transport regulator
GPY24_RS22260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPY24_RS22270	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GPY24_RS22280	COG1538	Outer membrane efflux protein
GPY24_RS22285	COG0494	nUDIX hydrolase
GPY24_RS22290	COG3151	Protein conserved in bacteria
GPY24_RS22305	COG0187	DNA topoisomerase II activity
GPY24_RS22320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPY24_RS22330	COG3105	Protein conserved in bacteria
GPY24_RS22335	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GPY24_RS22355	COG0723	plastoquinol--plastocyanin reductase activity
GPY24_RS22360	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GPY24_RS22365	COG2857	Cytochrome c1
GPY24_RS22370	COG0625	glutathione transferase activity
GPY24_RS22375	COG2969	positive regulation of protein catabolic process
GPY24_RS22400	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPY24_RS22420	COG0768	penicillin binding
GPY24_RS22435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPY24_RS22445	COG0772	Belongs to the SEDS family
GPY24_RS22460	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GPY24_RS22465	COG0849	cell division
GPY24_RS22470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPY24_RS22475	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GPY24_RS22480	COG0653	protein targeting
GPY24_RS22485	COG0494	nUDIX hydrolase
GPY24_RS22495	COG0505	Belongs to the CarA family
GPY24_RS22505	COG0730	response to heat
GPY24_RS22510	COG0583	DNA-binding transcription factor activity
GPY24_RS22525	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GPY24_RS22530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPY24_RS22540	COG0493	'glutamate synthase
GPY24_RS22560	COG1242	4 iron, 4 sulfur cluster binding
GPY24_RS22565	COG2203	Gaf domain
GPY24_RS22565	COG4251	negative regulation of phosphorylation
GPY24_RS22565	COG3706	GGDEF domain
GPY24_RS22565	COG5001	Diguanylate cyclase
GPY24_RS22570	COG5002	protein histidine kinase activity
GPY24_RS22570	COG2198	Histidine kinase
GPY24_RS22570	COG0784	Response regulator, receiver
GPY24_RS22580	COG0745	RESPONSE REGULATOR receiver
GPY24_RS22615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPY24_RS22630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPY24_RS22645	COG1115	amino acid carrier protein
GPY24_RS22650	COG3022	response to hydroperoxide
GPY24_RS22670	COG0716	FMN binding
GPY24_RS22680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY24_RS22695	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GPY24_RS22700	COG2204	response regulator
GPY24_RS22710	COG0667	Aldo Keto reductase