locus-tag	class	description
GPX87_RS00005	COG1763	Mo-molybdopterin cofactor biosynthetic process
GPX87_RS00015	COG1940	carbohydrate kinase activity
GPX87_RS00025	COG0791	NLP P60 protein
GPX87_RS00040	COG0393	Putative heavy-metal-binding
GPX87_RS00050	COG3639	organic phosphonate transmembrane transporter activity
GPX87_RS00055	COG3639	organic phosphonate transmembrane transporter activity
GPX87_RS00060	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GPX87_RS00070	COG0307	riboflavin synthase, alpha
GPX87_RS00080	COG1793	dna ligase
GPX87_RS00085	COG4667	esterase of the alpha-beta hydrolase superfamily
GPX87_RS00100	COG0848	biopolymer transport protein
GPX87_RS00105	COG0811	peptide transport
GPX87_RS00110	COG0811	peptide transport
GPX87_RS00120	COG2201	protein-glutamate methylesterase activity
GPX87_RS00125	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPX87_RS00130	COG0835	chemotaxis
GPX87_RS00140	COG0643	Histidine kinase
GPX87_RS00140	COG2198	Histidine kinase
GPX87_RS00150	COG0745	RESPONSE REGULATOR receiver
GPX87_RS00155	COG0840	transmembrane signaling receptor activity
GPX87_RS00165	COG1175	transmembrane transport
GPX87_RS00170	COG0395	ABC-type sugar transport system, permease component
GPX87_RS00175	COG3842	ATPase activity
GPX87_RS00180	COG1349	DNA-binding transcription factor activity
GPX87_RS00185	COG0584	glycerophosphoryl diester phosphodiesterase
GPX87_RS00195	COG2200	EAL domain
GPX87_RS00210	COG0477	Major facilitator Superfamily
GPX87_RS00215	COG0583	DNA-binding transcription factor activity
GPX87_RS00225	COG1643	Atp-dependent helicase
GPX87_RS00230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPX87_RS00250	COG3706	GGDEF domain
GPX87_RS00260	COG0443	Heat shock 70 kDa protein
GPX87_RS00265	COG0443	Heat shock 70 kDa protein
GPX87_RS00280	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPX87_RS00285	COG0602	queuosine metabolic process
GPX87_RS00290	COG0561	phosphatase activity
GPX87_RS00300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX87_RS00305	COG4597	amino acid ABC transporter
GPX87_RS00310	COG0765	amino acid transport
GPX87_RS00315	COG1126	abc transporter atp-binding protein
GPX87_RS00320	COG0670	Belongs to the BI1 family
GPX87_RS00325	COG2920	part of a sulfur-relay system
GPX87_RS00330	COG1254	Belongs to the acylphosphatase family
GPX87_RS00335	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPX87_RS00345	COG1294	oxidase, subunit
GPX87_RS00350	COG1271	oxidase subunit
GPX87_RS00355	COG3290	protein histidine kinase activity
GPX87_RS00370	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPX87_RS00380	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPX87_RS00385	COG1805	sodium ion transport
GPX87_RS00395	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPX87_RS00400	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPX87_RS00405	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPX87_RS00410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPX87_RS00415	COG1053	succinate dehydrogenase
GPX87_RS00420	COG0281	malic enzyme
GPX87_RS00450	COG0835	chemotaxis
GPX87_RS00450	COG0784	Response regulator, receiver
GPX87_RS00465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPX87_RS00480	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GPX87_RS00485	COG3063	Type IV pilus biogenesis stability protein PilW
GPX87_RS00495	COG1451	nucleotide metabolic process
GPX87_RS00505	COG0583	DNA-binding transcription factor activity
GPX87_RS00535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPX87_RS00555	COG4139	cobalamin transport
GPX87_RS00560	COG2988	succinylglutamate desuccinylase activity
GPX87_RS00575	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GPX87_RS00585	COG0702	epimerase
GPX87_RS00595	COG2925	Exonuclease
GPX87_RS00605	COG1346	cytolysis
GPX87_RS00610	COG0295	cytidine deaminase activity
GPX87_RS00615	COG3300	MHYT domain
GPX87_RS00615	COG5001	Diguanylate cyclase
GPX87_RS00620	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GPX87_RS00625	COG0500	methyltransferase
GPX87_RS00645	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPX87_RS00650	COG0456	acetyltransferase
GPX87_RS00680	COG1187	pseudouridine synthase activity
GPX87_RS00685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GPX87_RS00685	COG0140	phosphoribosyl-ATP diphosphatase activity
GPX87_RS00695	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPX87_RS00700	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPX87_RS00705	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPX87_RS00705	COG0131	Imidazoleglycerol-phosphate dehydratase
GPX87_RS00710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPX87_RS00715	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPX87_RS00720	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GPX87_RS00725	COG1757	Na H antiporter
GPX87_RS00730	COG2916	Histone family protein nucleoid-structuring protein H-NS
GPX87_RS00735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPX87_RS00740	COG0482	sulfurtransferase activity
GPX87_RS00745	COG2915	High frequency lysogenization protein hflD homolog
GPX87_RS00750	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPX87_RS00755	COG0501	Belongs to the peptidase M48B family
GPX87_RS00760	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GPX87_RS00770	COG0156	8-amino-7-oxononanoate synthase activity
GPX87_RS00775	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPX87_RS00790	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPX87_RS00790	COG2146	nitrite reductase [NAD(P)H] activity
GPX87_RS00795	COG1116	anion transmembrane transporter activity
GPX87_RS00800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GPX87_RS00805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GPX87_RS00820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPX87_RS00820	COG1648	precorrin-2 dehydrogenase activity
GPX87_RS00825	COG0243	molybdopterin cofactor binding
GPX87_RS00830	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPX87_RS00835	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GPX87_RS00840	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GPX87_RS00845	COG0653	protein targeting
GPX87_RS00855	COG3706	GGDEF domain
GPX87_RS00860	COG1122	ATPase activity
GPX87_RS00865	COG4120	Belongs to the binding-protein-dependent transport system permease family
GPX87_RS00880	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPX87_RS00885	COG0280	phosphate acetyltransferase
GPX87_RS00885	COG0857	belongs to the CobB CobQ family
GPX87_RS00890	COG0435	Glutathione S-transferase
GPX87_RS00975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPX87_RS00980	COG0601	transmembrane transport
GPX87_RS00995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPX87_RS01005	COG1621	beta-fructofuranosidase activity
GPX87_RS01015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX87_RS01015	COG1263	PTS System
GPX87_RS01020	COG0642	Histidine kinase
GPX87_RS01025	COG0745	RESPONSE REGULATOR receiver
GPX87_RS01040	COG1538	Outer membrane efflux protein
GPX87_RS01050	COG2207	Transcriptional regulator
GPX87_RS01050	COG3708	Transcriptional regulator
GPX87_RS01055	COG2814	Major facilitator Superfamily
GPX87_RS01060	COG1566	PFAM secretion protein HlyD family protein
GPX87_RS01065	COG1538	Outer membrane efflux protein
GPX87_RS01075	COG4166	transmembrane transport
GPX87_RS01080	COG0601	transmembrane transport
GPX87_RS01085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPX87_RS01090	COG4172	Belongs to the ABC transporter superfamily
GPX87_RS01095	COG0351	phosphomethylpyrimidine kinase
GPX87_RS01100	COG1741	Belongs to the pirin family
GPX87_RS01125	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPX87_RS01165	COG4964	Belongs to the GSP D family
GPX87_RS01205	COG0366	Alpha amylase catalytic
GPX87_RS01210	COG0840	transmembrane signaling receptor activity
GPX87_RS01215	COG1124	(ABC) transporter
GPX87_RS01225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPX87_RS01230	COG0601	transmembrane transport
GPX87_RS01235	COG0747	negative chemotaxis
GPX87_RS01260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPX87_RS01280	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GPX87_RS01285	COG1946	Acyl-CoA thioesterase
GPX87_RS01290	COG1522	sequence-specific DNA binding
GPX87_RS01295	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPX87_RS01300	COG3015	lipoprotein NlpE involved in copper resistance
GPX87_RS01320	COG0477	Major facilitator Superfamily
GPX87_RS01330	COG1441	menaquinone biosynthetic process
GPX87_RS01335	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPX87_RS01340	COG0596	Alpha beta hydrolase
GPX87_RS01345	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GPX87_RS01355	COG0436	Aminotransferase
GPX87_RS01360	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GPX87_RS01365	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GPX87_RS01380	COG0616	signal peptide processing
GPX87_RS01385	COG1028	Short-chain dehydrogenase reductase Sdr
GPX87_RS01390	COG0784	Response regulator, receiver
GPX87_RS01390	COG0835	chemotaxis
GPX87_RS01395	COG1940	carbohydrate kinase activity
GPX87_RS01405	COG4667	esterase of the alpha-beta hydrolase superfamily
GPX87_RS01415	COG0733	neurotransmitter:sodium symporter activity
GPX87_RS01430	COG1263	PTS System
GPX87_RS01430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX87_RS01435	COG0084	hydrolase, TatD family'
GPX87_RS01440	COG0470	DNA polymerase III
GPX87_RS01445	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPX87_RS01450	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPX87_RS01455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPX87_RS01460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPX87_RS01465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPX87_RS01480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPX87_RS01485	COG0416	fatty acid biosynthetic process
GPX87_RS01495	COG1399	metal-binding, possibly nucleic acid-binding protein
GPX87_RS01500	COG0424	maF-like protein
GPX87_RS01505	COG0564	pseudouridine synthase activity
GPX87_RS01510	COG1530	ribonuclease E activity
GPX87_RS01525	COG1454	alcohol dehydrogenase
GPX87_RS01525	COG1012	belongs to the aldehyde dehydrogenase family
GPX87_RS01530	COG2095	MarC family integral membrane protein
GPX87_RS01535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPX87_RS01540	COG1757	Na H antiporter
GPX87_RS01545	COG3081	Nucleoid-associated protein
GPX87_RS01555	COG3083	sulfuric ester hydrolase activity
GPX87_RS01575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPX87_RS01580	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPX87_RS01585	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPX87_RS01595	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPX87_RS01600	COG2832	Protein of unknown function (DUF454)
GPX87_RS01610	COG0745	RESPONSE REGULATOR receiver
GPX87_RS01615	COG0583	DNA-binding transcription factor activity
GPX87_RS01620	COG1024	Enoyl-CoA hydratase
GPX87_RS01620	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPX87_RS01625	COG0183	Belongs to the thiolase family
GPX87_RS01630	COG2067	long-chain fatty acid transport protein
GPX87_RS01635	COG2067	long-chain fatty acid transport protein
GPX87_RS01640	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GPX87_RS01645	COG2982	Protein involved in outer membrane biogenesis
GPX87_RS01650	COG0572	uridine kinase
GPX87_RS01655	COG0489	protein tyrosine kinase activity
GPX87_RS01660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPX87_RS01660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPX87_RS01670	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GPX87_RS01680	COG0517	IMP dehydrogenase activity
GPX87_RS01680	COG0516	GMP reductase activity
GPX87_RS01685	COG0314	molybdopterin synthase activity
GPX87_RS01690	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPX87_RS01700	COG0521	Mo-molybdopterin cofactor biosynthetic process
GPX87_RS01705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPX87_RS01710	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GPX87_RS01715	COG2198	Histidine kinase
GPX87_RS01720	COG2204	response regulator
GPX87_RS01755	COG1203	CRISPR-associated helicase, Cas3
GPX87_RS01760	COG1518	maintenance of DNA repeat elements
GPX87_RS01785	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPX87_RS01790	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPX87_RS01795	COG0583	DNA-binding transcription factor activity
GPX87_RS01800	COG2951	lytic endotransglycosylase activity
GPX87_RS01805	COG3100	YcgL domain-containing protein
GPX87_RS01815	COG2894	cell division
GPX87_RS01820	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GPX87_RS01825	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GPX87_RS01830	COG0318	PFAM AMP-dependent synthetase and ligase
GPX87_RS01835	COG1073	alpha beta
GPX87_RS01835	COG2226	methyltransferase
GPX87_RS01850	COG1214	PFAM Peptidase M22, glycoprotease
GPX87_RS01855	COG1199	ATP-dependent helicase activity
GPX87_RS01865	COG0788	formyltetrahydrofolate deformylase activity
GPX87_RS01870	COG1902	pentaerythritol trinitrate reductase activity
GPX87_RS01870	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPX87_RS01875	COG0616	signal peptide processing
GPX87_RS01880	COG0252	asparaginase activity
GPX87_RS01885	COG3139	Protein of unknown function (DUF1315)
GPX87_RS01895	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPX87_RS01910	COG2226	methyltransferase
GPX87_RS01920	COG3122	Protein conserved in bacteria
GPX87_RS01930	COG1403	HNH endonuclease
GPX87_RS01935	COG0840	transmembrane signaling receptor activity
GPX87_RS01940	COG3477	response to acidic pH
GPX87_RS01960	COG0840	transmembrane signaling receptor activity
GPX87_RS01965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPX87_RS01970	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GPX87_RS01990	COG2853	Lipoprotein
GPX87_RS01995	COG4235	cytochrome complex assembly
GPX87_RS02005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPX87_RS02010	COG1138	Cytochrome C-type biogenesis protein
GPX87_RS02015	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GPX87_RS02025	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPX87_RS02030	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPX87_RS02035	COG4133	protoheme IX ABC transporter activity
GPX87_RS02045	COG0835	chemotaxis
GPX87_RS02060	COG2198	Histidine kinase
GPX87_RS02060	COG0643	Histidine kinase
GPX87_RS02065	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GPX87_RS02080	COG0455	bacterial-type flagellum organization
GPX87_RS02095	COG2062	phosphohistidine phosphatase, SixA
GPX87_RS02100	COG1025	Belongs to the peptidase M16 family
GPX87_RS02105	COG3102	Protein conserved in bacteria
GPX87_RS02110	COG0018	arginyl-trna synthetase
GPX87_RS02130	COG1918	ferrous iron import across plasma membrane
GPX87_RS02140	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GPX87_RS02145	COG1121	(ABC) transporter
GPX87_RS02150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPX87_RS02165	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPX87_RS02170	COG0567	Dehydrogenase, E1 component
GPX87_RS02185	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GPX87_RS02190	COG2009	succinate dehydrogenase
GPX87_RS02200	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPX87_RS02210	COG0033	Phosphoglucomutase
GPX87_RS02215	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GPX87_RS02220	COG0596	Alpha beta hydrolase
GPX87_RS02235	COG1346	cytolysis
GPX87_RS02240	COG1380	Effector of murein hydrolase LrgA
GPX87_RS02245	COG0583	DNA-binding transcription factor activity
GPX87_RS02260	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPX87_RS02265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPX87_RS02270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPX87_RS02275	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GPX87_RS02275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPX87_RS02290	COG3101	peptidyl-lysine hydroxylation
GPX87_RS02295	COG2860	membrane
GPX87_RS02300	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPX87_RS02305	COG2890	protein-(glutamine-N5) methyltransferase activity
GPX87_RS02325	COG1987	bacterial-type flagellum assembly
GPX87_RS02375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPX87_RS02385	COG1677	Flagellar hook-basal body complex protein FliE
GPX87_RS02390	COG2204	response regulator
GPX87_RS02395	COG4191	Histidine kinase
GPX87_RS02400	COG2204	response regulator
GPX87_RS02405	COG1516	flagellar protein fliS
GPX87_RS02415	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPX87_RS02420	COG1334	flagellar protein FlaG
GPX87_RS02425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPX87_RS02430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPX87_RS02440	COG2837	iron assimilation
GPX87_RS02465	COG4580	involved in the transport of maltose and maltodextrins
GPX87_RS02470	COG1874	Beta-galactosidase
GPX87_RS02480	COG3833	ABC-type maltose transport systems, permease component
GPX87_RS02485	COG1175	transmembrane transport
GPX87_RS02500	COG1609	Transcriptional regulator
GPX87_RS02510	COG2017	converts alpha-aldose to the beta-anomer
GPX87_RS02520	COG1085	galactose-1-phosphate uridylyltransferase
GPX87_RS02525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPX87_RS02535	COG1393	Belongs to the ArsC family
GPX87_RS02540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPX87_RS02545	COG1876	peptidase activity
GPX87_RS02555	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GPX87_RS02560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPX87_RS02565	COG2716	regulation of RNA biosynthetic process
GPX87_RS02570	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPX87_RS02590	COG4783	chaperone-mediated protein folding
GPX87_RS02595	COG1393	Belongs to the ArsC family
GPX87_RS02625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPX87_RS02630	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GPX87_RS02635	COG2912	Transglutaminase-like superfamily
GPX87_RS02640	COG3094	Invasion gene expression up-regulator, SirB
GPX87_RS02645	COG2890	protein-(glutamine-N5) methyltransferase activity
GPX87_RS02650	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPX87_RS02655	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPX87_RS02660	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GPX87_RS02670	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPX87_RS02680	COG0012	GTP binding
GPX87_RS02760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPX87_RS02765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPX87_RS02770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPX87_RS02780	COG3951	Flagellar rod assembly protein muramidase FlgJ
GPX87_RS02780	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPX87_RS02785	COG1706	bacterial-type flagellum-dependent cell motility
GPX87_RS02790	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GPX87_RS02795	COG4786	Flagellar basal body rod
GPX87_RS02800	COG4787	bacterial-type flagellum-dependent cell motility
GPX87_RS02805	COG1749	Flagellar hook protein flgE
GPX87_RS02810	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPX87_RS02815	COG1558	bacterial-type flagellum-dependent cell motility
GPX87_RS02820	COG1815	bacterial-type flagellum-dependent cell motility
GPX87_RS02825	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPX87_RS02830	COG0784	Response regulator, receiver
GPX87_RS02830	COG0835	chemotaxis
GPX87_RS02840	COG2747	anti-sigma28 factor FlgM
GPX87_RS02890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPX87_RS02895	COG2608	mercury ion transmembrane transporter activity
GPX87_RS02895	COG2217	Heavy metal translocating P-type atpase
GPX87_RS02915	COG2840	Smr protein MutS2
GPX87_RS02920	COG1187	pseudouridine synthase activity
GPX87_RS02925	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPX87_RS02930	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GPX87_RS02935	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPX87_RS02940	COG0121	glutamine amidotransferase
GPX87_RS02945	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPX87_RS02950	COG1960	acyl-CoA dehydrogenase activity
GPX87_RS02960	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPX87_RS02965	COG0328	RNA-DNA hybrid ribonuclease activity
GPX87_RS02970	COG2226	methyltransferase
GPX87_RS02975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPX87_RS02980	COG1388	LysM domain
GPX87_RS02980	COG0741	lytic transglycosylase activity
GPX87_RS02990	COG0347	Belongs to the P(II) protein family
GPX87_RS03000	COG0037	tRNA processing
GPX87_RS03005	COG0825	malonyl-CoA metabolic process
GPX87_RS03010	COG0587	DNA-directed DNA polymerase activity
GPX87_RS03015	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPX87_RS03020	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPX87_RS03025	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPX87_RS03030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPX87_RS03035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPX87_RS03040	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GPX87_RS03050	COG0750	zinc metalloprotease
GPX87_RS03055	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GPX87_RS03060	COG0575	Belongs to the CDS family
GPX87_RS03065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPX87_RS03070	COG0233	cytoplasmic translational termination
GPX87_RS03080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPX87_RS03090	COG0024	Methionine aminopeptidase
GPX87_RS03095	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GPX87_RS03100	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GPX87_RS03105	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GPX87_RS03110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPX87_RS03130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPX87_RS03130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPX87_RS03135	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPX87_RS03140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPX87_RS03145	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPX87_RS03160	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GPX87_RS03165	COG2252	PERMEase
GPX87_RS03170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GPX87_RS03180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPX87_RS03190	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPX87_RS03195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPX87_RS03200	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPX87_RS03205	COG4067	protein conserved in archaea
GPX87_RS03205	COG0189	ligase activity
GPX87_RS03210	COG0189	ligase activity
GPX87_RS03220	COG0733	neurotransmitter:sodium symporter activity
GPX87_RS03230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPX87_RS03245	COG1477	protein flavinylation
GPX87_RS03255	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPX87_RS03265	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPX87_RS03270	COG1805	sodium ion transport
GPX87_RS03280	COG0271	Belongs to the BolA IbaG family
GPX87_RS03295	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPX87_RS03340	COG0542	response to heat
GPX87_RS03350	COG0564	pseudouridine synthase activity
GPX87_RS03355	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPX87_RS03360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPX87_RS03365	COG0077	Prephenate dehydratase
GPX87_RS03365	COG1605	Chorismate mutase
GPX87_RS03370	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GPX87_RS03375	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GPX87_RS03380	COG0741	lytic transglycosylase activity
GPX87_RS03385	COG0488	(ABC) transporter
GPX87_RS03395	COG1605	Chorismate mutase
GPX87_RS03395	COG0287	Prephenate dehydrogenase
GPX87_RS03400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPX87_RS03405	COG3275	phosphorelay sensor kinase activity
GPX87_RS03410	COG3279	Response regulator of the LytR AlgR family
GPX87_RS03420	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GPX87_RS03430	COG1966	Carbon starvation protein
GPX87_RS03435	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GPX87_RS03440	COG1047	Peptidyl-prolyl cis-trans
GPX87_RS03445	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPX87_RS03450	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPX87_RS03455	COG0196	riboflavin kinase activity
GPX87_RS03460	COG0728	peptidoglycan biosynthetic process
GPX87_RS03470	COG0640	Transcriptional regulator
GPX87_RS03475	COG0583	DNA-binding transcription factor activity
GPX87_RS03480	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPX87_RS03490	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPX87_RS03495	COG0730	response to heat
GPX87_RS03505	COG0494	nUDIX hydrolase
GPX87_RS03510	COG3066	DNA modification
GPX87_RS03515	COG0667	Aldo Keto reductase
GPX87_RS03520	COG2204	response regulator
GPX87_RS03525	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GPX87_RS03540	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GPX87_RS03545	COG0513	Belongs to the DEAD box helicase family
GPX87_RS03565	COG3153	acetyltransferase
GPX87_RS03595	COG1185	polyribonucleotide nucleotidyltransferase activity
GPX87_RS03600	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPX87_RS03605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPX87_RS03610	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPX87_RS03620	COG0195	Participates in both transcription termination and antitermination
GPX87_RS03625	COG0779	Required for maturation of 30S ribosomal subunits
GPX87_RS03640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPX87_RS03645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPX87_RS03650	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPX87_RS03655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPX87_RS03660	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GPX87_RS03665	COG1534	Rna-binding protein
GPX87_RS03670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPX87_RS03675	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPX87_RS03680	COG2027	D-alanyl-D-alanine carboxypeptidase
GPX87_RS03685	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPX87_RS03690	COG0739	heme binding
GPX87_RS03695	COG0316	Belongs to the HesB IscA family
GPX87_RS03700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GPX87_RS03705	COG0628	permease
GPX87_RS03720	COG0747	negative chemotaxis
GPX87_RS03735	COG0444	Belongs to the ABC transporter superfamily
GPX87_RS03740	COG4608	Belongs to the ABC transporter superfamily
GPX87_RS03750	COG2971	BadF BadG BcrA BcrD
GPX87_RS03765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPX87_RS03770	COG1840	ABC-type Fe3 transport system, periplasmic component
GPX87_RS03785	COG0004	ammonium transporteR
GPX87_RS03790	COG0347	Belongs to the P(II) protein family
GPX87_RS03800	COG4771	TonB-dependent receptor
GPX87_RS03805	COG2205	protein histidine kinase activity
GPX87_RS03810	COG0745	RESPONSE REGULATOR receiver
GPX87_RS03815	COG1049	propionate catabolic process, 2-methylcitrate cycle
GPX87_RS03820	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPX87_RS03825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPX87_RS03830	COG1643	Atp-dependent helicase
GPX87_RS03835	COG0589	response to stress
GPX87_RS03845	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPX87_RS03850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPX87_RS03860	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPX87_RS03865	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GPX87_RS03870	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GPX87_RS03875	COG0842	Transport permease protein
GPX87_RS03880	COG1131	(ABC) transporter
GPX87_RS03885	COG0288	reversible hydration of carbon dioxide
GPX87_RS03900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPX87_RS03905	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPX87_RS03910	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GPX87_RS03915	COG2186	Transcriptional regulator
GPX87_RS03920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GPX87_RS03925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPX87_RS03930	COG4974	Belongs to the 'phage' integrase family
GPX87_RS03935	COG0716	FMN binding
GPX87_RS03945	COG0157	Belongs to the NadC ModD family
GPX87_RS03955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPX87_RS03960	COG1459	type II secretion system
GPX87_RS03970	COG0237	dephospho-CoA kinase activity
GPX87_RS03975	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GPX87_RS03980	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GPX87_RS03990	COG0187	DNA topoisomerase II activity
GPX87_RS03995	COG3150	esterase
GPX87_RS04005	COG3151	Protein conserved in bacteria
GPX87_RS04010	COG0494	nUDIX hydrolase
GPX87_RS04015	COG1538	Outer membrane efflux protein
GPX87_RS04025	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GPX87_RS04035	COG3025	triphosphatase activity
GPX87_RS04040	COG1392	Phosphate transport regulator
GPX87_RS04045	COG0306	phosphate transporter
GPX87_RS04050	COG4991	sh3 domain protein
GPX87_RS04055	COG0617	tRNA 3'-terminal CCA addition
GPX87_RS04060	COG0148	phosphopyruvate hydratase activity
GPX87_RS04065	COG0504	CTP synthase activity
GPX87_RS04070	COG3956	TIGRFAM MazG family protein
GPX87_RS04075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPX87_RS04080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPX87_RS04095	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GPX87_RS04100	COG1381	Involved in DNA repair and RecF pathway recombination
GPX87_RS04105	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPX87_RS04110	COG0571	ribonuclease III activity
GPX87_RS04115	COG0681	Belongs to the peptidase S26 family
GPX87_RS04120	COG0481	GTPase activity
GPX87_RS04125	COG3086	response to oxidative stress
GPX87_RS04130	COG3026	antisigma factor binding
GPX87_RS04140	COG1595	DNA-templated transcription, initiation
GPX87_RS04145	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GPX87_RS04155	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GPX87_RS04160	COG0354	folic acid binding
GPX87_RS04175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPX87_RS04180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPX87_RS04190	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPX87_RS04200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPX87_RS04205	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GPX87_RS04210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPX87_RS04220	COG0028	Belongs to the TPP enzyme family
GPX87_RS04225	COG1022	Amp-dependent synthetase and ligase
GPX87_RS04230	COG0583	DNA-binding transcription factor activity
GPX87_RS04245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPX87_RS04250	COG0473	3-isopropylmalate dehydrogenase activity
GPX87_RS04255	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPX87_RS04260	COG0066	3-isopropylmalate dehydratase activity
GPX87_RS04325	COG3437	response regulator, receiver
GPX87_RS04330	COG5001	Diguanylate cyclase
GPX87_RS04345	COG0795	lipopolysaccharide-transporting ATPase activity
GPX87_RS04350	COG0795	lipopolysaccharide-transporting ATPase activity
GPX87_RS04360	COG2927	DNA polymerase III (CHI subunit)
GPX87_RS04365	COG0525	valine-tRNA ligase activity
GPX87_RS04370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPX87_RS04375	COG0564	pseudouridine synthase activity
GPX87_RS04385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GPX87_RS04390	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GPX87_RS04395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPX87_RS04405	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GPX87_RS04410	COG0251	oxidation-reduction process
GPX87_RS04415	COG0204	Acyl-transferase
GPX87_RS04420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPX87_RS04425	COG5007	Belongs to the BolA IbaG family
GPX87_RS04435	COG2854	intermembrane phospholipid transfer
GPX87_RS04440	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPX87_RS04445	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GPX87_RS04450	COG1127	ABC transporter
GPX87_RS04465	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GPX87_RS04470	COG3117	lipopolysaccharide transmembrane transporter activity
GPX87_RS04475	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GPX87_RS04480	COG1137	ATPase activity
GPX87_RS04490	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPX87_RS04495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX87_RS04505	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX87_RS04510	COG2239	Acts as a magnesium transporter
GPX87_RS04515	COG0312	modulator of DNA gyrase
GPX87_RS04520	COG3028	Belongs to the UPF0307 family
GPX87_RS04525	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GPX87_RS04530	COG1178	ABC-type Fe3 transport system permease component
GPX87_RS04535	COG4143	(ABC) transporter
GPX87_RS04540	COG0163	prenyltransferase activity
GPX87_RS04545	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPX87_RS04550	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GPX87_RS04555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GPX87_RS04560	COG2105	PFAM AIG2 family protein
GPX87_RS04570	COG0729	surface antigen
GPX87_RS04575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPX87_RS04580	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GPX87_RS04595	COG1136	(ABC) transporter
GPX87_RS04615	COG0529	Catalyzes the synthesis of activated sulfate
GPX87_RS04620	COG2895	sulfate adenylyltransferase (ATP) activity
GPX87_RS04625	COG0175	sulfate reduction
GPX87_RS04630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPX87_RS04630	COG1648	precorrin-2 dehydrogenase activity
GPX87_RS04635	COG0737	Belongs to the 5'-nucleotidase family
GPX87_RS04640	COG0513	Belongs to the DEAD box helicase family
GPX87_RS04645	COG2153	protein acetylation
GPX87_RS04655	COG0545	Peptidyl-prolyl cis-trans isomerase
GPX87_RS04660	COG0203	ribosomal protein L17
GPX87_RS04665	COG0202	RNA polymerase activity
GPX87_RS04670	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPX87_RS04675	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPX87_RS04690	COG0201	protein transport
GPX87_RS04700	COG1841	ribosomal large subunit assembly
GPX87_RS04715	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPX87_RS04720	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPX87_RS04730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPX87_RS04735	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPX87_RS04740	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPX87_RS04750	COG0255	Belongs to the universal ribosomal protein uL29 family
GPX87_RS04760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPX87_RS04765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPX87_RS04770	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPX87_RS04780	COG0089	rRNA binding
GPX87_RS04785	COG0088	Forms part of the polypeptide exit tunnel
GPX87_RS04790	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPX87_RS04795	COG0051	transcription antitermination factor activity, RNA binding
GPX87_RS04800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPX87_RS04805	COG0557	exoribonuclease II activity
GPX87_RS04810	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GPX87_RS04815	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPX87_RS04820	COG1047	Peptidyl-prolyl cis-trans
GPX87_RS04840	COG0488	(ABC) transporter
GPX87_RS04850	COG0429	hydrolase of the alpha beta-hydrolase fold
GPX87_RS04860	COG3954	Phosphoribulokinase
GPX87_RS04865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPX87_RS04885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPX87_RS04895	COG0180	Tryptophanyl-tRNA synthetase
GPX87_RS04900	COG0546	phosphoglycolate phosphatase activity
GPX87_RS04905	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPX87_RS04910	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GPX87_RS04920	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPX87_RS04955	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GPX87_RS04965	COG0678	peroxiredoxin activity
GPX87_RS04965	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPX87_RS04975	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPX87_RS04975	COG0165	Argininosuccinate lyase
GPX87_RS04985	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPX87_RS04990	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPX87_RS04995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPX87_RS05000	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GPX87_RS05010	COG1045	serine acetyltransferase
GPX87_RS05025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPX87_RS05030	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GPX87_RS05035	COG1053	succinate dehydrogenase
GPX87_RS05040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPX87_RS05045	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPX87_RS05060	COG1509	lysine 2,3-aminomutase activity
GPX87_RS05065	COG1285	pathogenesis
GPX87_RS05070	COG1119	ATPase activity
GPX87_RS05075	COG0459	protein refolding
GPX87_RS05080	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPX87_RS05110	COG0534	Mate efflux family protein
GPX87_RS05115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPX87_RS05120	COG1575	Belongs to the MenA family. Type 1 subfamily
GPX87_RS05125	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GPX87_RS05130	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GPX87_RS05140	COG1609	Transcriptional regulator
GPX87_RS05145	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPX87_RS05155	COG0281	malic enzyme
GPX87_RS05165	COG0626	cystathionine gamma-synthase activity
GPX87_RS05170	COG0527	aspartate kinase activity
GPX87_RS05170	COG0460	homoserine dehydrogenase
GPX87_RS05175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPX87_RS05185	COG1494	fructose-1,6-bisphosphatase
GPX87_RS05190	COG0205	6-phosphofructokinase activity
GPX87_RS05195	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPX87_RS05205	COG0745	RESPONSE REGULATOR receiver
GPX87_RS05210	COG2205	protein histidine kinase activity
GPX87_RS05215	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GPX87_RS05220	COG1278	Cold shock
GPX87_RS05225	COG3030	protein affecting phage T7 exclusion by the F plasmid
GPX87_RS05230	COG1027	Aspartate ammonia-lyase
GPX87_RS05235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPX87_RS05245	COG4232	protein-disulfide reductase activity
GPX87_RS05260	COG3263	regulation of cellular component size
GPX87_RS05270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPX87_RS05275	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPX87_RS05280	COG0194	GDP metabolic process
GPX87_RS05290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPX87_RS05295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPX87_RS05300	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPX87_RS05305	COG2233	PERMEase
GPX87_RS05310	COG2205	protein histidine kinase activity
GPX87_RS05315	COG0745	RESPONSE REGULATOR receiver
GPX87_RS05320	COG0800	Aldolase
GPX87_RS05325	COG2610	gluconate transmembrane transporter activity
GPX87_RS05330	COG3265	gluconokinase activity
GPX87_RS05335	COG0129	dihydroxy-acid dehydratase activity
GPX87_RS05340	COG1609	Transcriptional regulator
GPX87_RS05345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPX87_RS05355	COG2183	response to ionizing radiation
GPX87_RS05370	COG1040	competence protein
GPX87_RS05375	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GPX87_RS05375	COG0316	Belongs to the HesB IscA family
GPX87_RS05380	COG0494	nUDIX hydrolase
GPX87_RS05385	COG1218	3'(2'),5'-bisphosphate nucleotidase
GPX87_RS05395	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPX87_RS05400	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPX87_RS05405	COG3156	type II secretion system protein K
GPX87_RS05410	COG4795	General secretion pathway protein
GPX87_RS05415	COG2165	general secretion pathway protein
GPX87_RS05420	COG2165	general secretion pathway protein
GPX87_RS05425	COG2165	general secretion pathway protein
GPX87_RS05430	COG1459	type II secretion system
GPX87_RS05435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPX87_RS05445	COG3031	protein transport across the cell outer membrane
GPX87_RS05450	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GPX87_RS05455	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPX87_RS05460	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GPX87_RS05470	COG0456	acetyltransferase
GPX87_RS05475	COG1490	D-aminoacyl-tRNA deacylase activity
GPX87_RS05490	COG0174	glutamine synthetase
GPX87_RS05500	COG3852	Histidine kinase
GPX87_RS05505	COG2204	response regulator
GPX87_RS05510	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPX87_RS05550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GPX87_RS05555	COG4206	TonB-dependent receptor
GPX87_RS05575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPX87_RS05580	COG0534	Mate efflux family protein
GPX87_RS05590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPX87_RS05595	COG2937	Belongs to the GPAT DAPAT family
GPX87_RS05600	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GPX87_RS05605	COG3161	chorismate lyase activity
GPX87_RS05610	COG1580	Controls the rotational direction of flagella during chemotaxis
GPX87_RS05625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPX87_RS05630	COG2177	Part of the ABC transporter FtsEX involved in
GPX87_RS05635	COG2884	Cell division ATP-binding protein ftsE
GPX87_RS05640	COG0552	protein localization to endoplasmic reticulum
GPX87_RS05645	COG0742	ribosomal rna small subunit methyltransferase
GPX87_RS05670	COG0783	Belongs to the Dps family
GPX87_RS05675	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPX87_RS05685	COG0561	phosphatase activity
GPX87_RS05700	COG2200	EAL domain
GPX87_RS05700	COG3287	FIST C domain
GPX87_RS05700	COG2199	diguanylate cyclase activity
GPX87_RS05705	COG1011	Hydrolase
GPX87_RS05710	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GPX87_RS05725	COG0019	diaminopimelate decarboxylase activity
GPX87_RS05740	COG3072	Adenylate cyclase
GPX87_RS05750	COG1587	Uroporphyrinogen-III synthase
GPX87_RS05755	COG2959	enzyme of heme biosynthesis
GPX87_RS05760	COG3071	HemY protein
GPX87_RS05765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPX87_RS05790	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GPX87_RS05795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPX87_RS05795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPX87_RS05805	COG0084	hydrolase, TatD family'
GPX87_RS05810	COG0805	protein transport
GPX87_RS05815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPX87_RS05820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPX87_RS05825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GPX87_RS05830	COG3165	ubiquinone biosynthetic process from chorismate
GPX87_RS05840	COG1322	Protein conserved in bacteria
GPX87_RS05855	COG2160	L-arabinose isomerase activity
GPX87_RS05860	COG0235	Class ii aldolase
GPX87_RS05865	COG1069	ribulokinase activity
GPX87_RS05870	COG1879	ABC-type sugar transport system periplasmic component
GPX87_RS05875	COG1129	ABC transporter
GPX87_RS05880	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPX87_RS05885	COG0840	transmembrane signaling receptor activity
GPX87_RS05890	COG2081	HI0933 family
GPX87_RS05900	COG1528	Iron-storage protein
GPX87_RS05905	COG0589	response to stress
GPX87_RS05910	COG0697	spore germination
GPX87_RS05920	COG0742	ribosomal rna small subunit methyltransferase
GPX87_RS05925	COG1522	sequence-specific DNA binding
GPX87_RS05945	COG0006	proline dipeptidase activity
GPX87_RS05945	COG0006	proline dipeptidase activity
GPX87_RS05950	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPX87_RS05955	COG2022	thiamine diphosphate biosynthetic process
GPX87_RS05960	COG2104	thiamine diphosphate biosynthetic process
GPX87_RS05965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPX87_RS05975	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GPX87_RS05980	COG0038	chloride channel
GPX87_RS05995	COG0366	Alpha amylase catalytic
GPX87_RS06000	COG3977	Valine--pyruvate aminotransferase
GPX87_RS06005	COG0071	Belongs to the small heat shock protein (HSP20) family
GPX87_RS06020	COG0187	DNA topoisomerase II activity
GPX87_RS06030	COG0592	DNA-directed DNA polymerase activity
GPX87_RS06035	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPX87_RS06040	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GPX87_RS06050	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GPX87_RS06055	COG0706	membrane insertase activity
GPX87_RS06060	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPX87_RS06065	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPX87_RS06070	COG0445	tRNA wobble uridine modification
GPX87_RS06075	COG0357	Ribosomal RNA small subunit methyltransferase G
GPX87_RS06080	COG1192	Involved in chromosome partitioning
GPX87_RS06085	COG1475	DNA binding
GPX87_RS06095	COG0356	it plays a direct role in the translocation of protons across the membrane
GPX87_RS06105	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPX87_RS06115	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPX87_RS06120	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPX87_RS06130	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GPX87_RS06140	COG2814	Major facilitator Superfamily
GPX87_RS06145	COG0583	DNA-binding transcription factor activity
GPX87_RS06150	COG0183	Belongs to the thiolase family
GPX87_RS06160	COG1739	Uncharacterized protein family UPF0029
GPX87_RS06165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPX87_RS06240	COG0751	glycine-tRNA ligase activity
GPX87_RS06245	COG0752	glycyl-tRNA synthetase alpha subunit
GPX87_RS06250	COG2119	membrane
GPX87_RS06260	COG0425	Belongs to the sulfur carrier protein TusA family
GPX87_RS06265	COG0604	alcohol dehydrogenase
GPX87_RS06275	COG0129	dihydroxy-acid dehydratase activity
GPX87_RS06280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPX87_RS06285	COG3978	acetolactate synthase activity
GPX87_RS06295	COG0606	chelatase, subunit chli
GPX87_RS06300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPX87_RS06305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPX87_RS06315	COG3084	Protein conserved in bacteria
GPX87_RS06330	COG1272	protein, Hemolysin III
GPX87_RS06340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPX87_RS06345	COG0569	domain protein
GPX87_RS06350	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPX87_RS06350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPX87_RS06360	COG0242	peptide deformylase activity
GPX87_RS06370	COG0758	DNA mediated transformation
GPX87_RS06380	COG0551	DNA topoisomerase type I activity
GPX87_RS06385	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPX87_RS06395	COG0009	L-threonylcarbamoyladenylate synthase
GPX87_RS06400	COG0408	coproporphyrinogen oxidase activity
GPX87_RS06405	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPX87_RS06415	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPX87_RS06455	COG3335	DDE superfamily endonuclease
GPX87_RS06460	COG0583	DNA-binding transcription factor activity
GPX87_RS06465	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPX87_RS06470	COG2960	long-chain fatty acid transporting porin activity
GPX87_RS06475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPX87_RS06480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPX87_RS06485	COG3335	DDE superfamily endonuclease
GPX87_RS06525	COG4172	Belongs to the ABC transporter superfamily
GPX87_RS06530	COG0747	negative chemotaxis
GPX87_RS06540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPX87_RS06550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPX87_RS06555	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GPX87_RS06560	COG0339	signal peptide processing
GPX87_RS06565	COG0210	DNA helicase
GPX87_RS06570	COG1280	lysine exporter protein (LysE YggA)
GPX87_RS06580	COG2962	Rard protein
GPX87_RS06585	COG0514	ATP-dependent DNA helicase (RecQ)
GPX87_RS06600	COG3335	DDE superfamily endonuclease
GPX87_RS06615	COG1120	ATPase activity
GPX87_RS06620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPX87_RS06640	COG1228	amidohydrolase
GPX87_RS06655	COG4565	transcriptional regulatory protein
GPX87_RS06665	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPX87_RS06670	COG5016	pyruvate
GPX87_RS06670	COG0511	ligase activity, forming carbon-carbon bonds
GPX87_RS06675	COG3630	sodium ion export across plasma membrane
GPX87_RS06685	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GPX87_RS06690	COG3052	prosthetic group binding
GPX87_RS06695	COG2301	Belongs to the HpcH HpaI aldolase family
GPX87_RS06700	COG3051	citrate lyase alpha subunit
GPX87_RS06705	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
GPX87_RS06710	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GPX87_RS06725	COG1561	YicC-like family, N-terminal region
GPX87_RS06735	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPX87_RS06740	COG1560	Kdo2-lipid A biosynthetic process
GPX87_RS06745	COG1309	transcriptional regulator
GPX87_RS06750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPX87_RS06765	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GPX87_RS06770	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GPX87_RS06780	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GPX87_RS06790	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPX87_RS06795	COG0438	transferase activity, transferring glycosyl groups
GPX87_RS06800	COG0438	transferase activity, transferring glycosyl groups
GPX87_RS06805	COG0463	Glycosyl transferase, family 2
GPX87_RS06810	COG0859	PFAM glycosyl transferase family 9
GPX87_RS06815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPX87_RS06830	COG1519	Transferase
GPX87_RS06835	COG0859	PFAM glycosyl transferase family 9
GPX87_RS06850	COG1560	Kdo2-lipid A biosynthetic process
GPX87_RS06860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPX87_RS06870	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPX87_RS06925	COG5433	transposase activity
GPX87_RS06950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPX87_RS06965	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GPX87_RS06975	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GPX87_RS06995	COG0737	Belongs to the 5'-nucleotidase family
GPX87_RS07000	COG1573	uracil-dna glycosylase
GPX87_RS07005	COG3068	Protein conserved in bacteria
GPX87_RS07010	COG0668	transmembrane transport
GPX87_RS07015	COG1253	flavin adenine dinucleotide binding
GPX87_RS07020	COG0776	regulation of translation
GPX87_RS07045	COG3710	Transcriptional regulator
GPX87_RS07050	COG0531	amino acid
GPX87_RS07055	COG1982	Orn Lys Arg decarboxylase major
GPX87_RS07060	COG0840	transmembrane signaling receptor activity
GPX87_RS07065	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GPX87_RS07070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPX87_RS07075	COG2264	protein methyltransferase activity
GPX87_RS07080	COG0439	Biotin carboxylase
GPX87_RS07085	COG0511	ligase activity, forming carbon-carbon bonds
GPX87_RS07090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GPX87_RS07095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPX87_RS07110	COG2814	Major facilitator Superfamily
GPX87_RS07115	COG2198	Histidine kinase
GPX87_RS07115	COG2205	protein histidine kinase activity
GPX87_RS07115	COG0784	Response regulator, receiver
GPX87_RS07115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX87_RS07120	COG0248	Ppx GppA phosphatase
GPX87_RS07130	COG3118	belongs to the thioredoxin family
GPX87_RS07135	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPX87_RS07140	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GPX87_RS07205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPX87_RS07215	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GPX87_RS07225	COG1072	(Pantothenic acid kinase))
GPX87_RS07255	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPX87_RS07260	COG0250	Participates in transcription elongation, termination and antitermination
GPX87_RS07270	COG0081	regulation of translation
GPX87_RS07275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPX87_RS07280	COG0222	ribosome binding
GPX87_RS07285	COG0085	RNA polymerase activity
GPX87_RS07290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPX87_RS07295	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GPX87_RS07300	COG2816	NAD+ diphosphatase activity
GPX87_RS07305	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GPX87_RS07320	COG4942	peptidase
GPX87_RS07325	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPX87_RS07330	COG0471	metal ion transport
GPX87_RS07340	COG1162	GTPase activity
GPX87_RS07345	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GPX87_RS07400	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPX87_RS07405	COG0802	atpase or kinase
GPX87_RS07415	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPX87_RS07420	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPX87_RS07425	COG1923	regulation of RNA biosynthetic process
GPX87_RS07430	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPX87_RS07435	COG0330	HflC and HflK could
GPX87_RS07440	COG0330	HflC and HflK could
GPX87_RS07445	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GPX87_RS07460	COG0545	Peptidyl-prolyl cis-trans isomerase
GPX87_RS07465	COG2964	Protein conserved in bacteria
GPX87_RS07470	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GPX87_RS07475	COG2923	Belongs to the DsrF TusC family
GPX87_RS07480	COG2168	tRNA wobble position uridine thiolation
GPX87_RS07490	COG0049	tRNA binding
GPX87_RS07495	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPX87_RS07505	COG2906	2 iron, 2 sulfur cluster binding
GPX87_RS07515	COG0360	Binds together with S18 to 16S ribosomal RNA
GPX87_RS07535	COG0305	Participates in initiation and elongation during chromosome replication
GPX87_RS07540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPX87_RS07545	COG0166	Belongs to the GPI family
GPX87_RS07555	COG0735	belongs to the Fur family
GPX87_RS07560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPX87_RS07580	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPX87_RS07585	COG0175	sulfate reduction
GPX87_RS07625	COG1410	methionine synthase
GPX87_RS07625	COG0646	methionine synthase
GPX87_RS07630	COG0527	aspartate kinase activity
GPX87_RS07635	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPX87_RS07645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPX87_RS07655	COG2197	response regulator
GPX87_RS07665	COG2200	EAL domain
GPX87_RS07665	COG2199	diguanylate cyclase activity
GPX87_RS07690	COG3267	Type II secretory pathway component ExeA
GPX87_RS07690	COG3409	Peptidoglycan-binding domain 1 protein
GPX87_RS07700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPX87_RS07750	COG1077	Cell shape determining protein MreB Mrl
GPX87_RS07755	COG1792	Involved in formation and maintenance of cell shape
GPX87_RS07760	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GPX87_RS07765	COG0424	maF-like protein
GPX87_RS07770	COG1530	ribonuclease E activity
GPX87_RS07775	COG3164	Protein of unknown function
GPX87_RS07780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPX87_RS07785	COG0312	modulator of DNA gyrase
GPX87_RS07805	COG0589	response to stress
GPX87_RS07830	COG0142	geranyltranstransferase activity
GPX87_RS07835	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GPX87_RS07845	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPX87_RS07850	COG2966	Psort location CytoplasmicMembrane, score
GPX87_RS07855	COG3610	response to peptide
GPX87_RS07865	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GPX87_RS07870	COG2967	ApaG domain
GPX87_RS07875	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GPX87_RS07880	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GPX87_RS07885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPX87_RS07890	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GPX87_RS07895	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPX87_RS07925	COG0840	transmembrane signaling receptor activity
GPX87_RS07950	COG0741	lytic transglycosylase activity
GPX87_RS07955	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GPX87_RS07960	COG1194	a g-specific adenine glycosylase
GPX87_RS07965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GPX87_RS07975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPX87_RS07990	COG1872	DUF167
GPX87_RS07995	COG0762	integral membrane protein
GPX87_RS08000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPX87_RS08005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPX87_RS08015	COG2805	Type II/IV secretion system protein
GPX87_RS08020	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPX87_RS08025	COG1678	Uncharacterized ACR, COG1678
GPX87_RS08030	COG0189	ligase activity
GPX87_RS08035	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GPX87_RS08040	COG2356	endonuclease I
GPX87_RS08055	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPX87_RS08060	COG0583	DNA-binding transcription factor activity
GPX87_RS08065	COG4771	TonB-dependent receptor
GPX87_RS08070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPX87_RS08075	COG0126	phosphoglycerate kinase activity
GPX87_RS08080	COG0191	fructose-bisphosphate aldolase activity
GPX87_RS08085	COG0668	transmembrane transport
GPX87_RS08095	COG5001	Diguanylate cyclase
GPX87_RS08095	COG5002	protein histidine kinase activity
GPX87_RS08095	COG3447	MASE1 domain protein
GPX87_RS08100	COG0469	pyruvate kinase activity
GPX87_RS08105	COG1349	DNA-binding transcription factor activity
GPX87_RS08115	COG1929	Belongs to the glycerate kinase type-1 family
GPX87_RS08120	COG1070	Carbohydrate kinase
GPX87_RS08125	COG1609	Transcriptional regulator
GPX87_RS08125	COG2207	Transcriptional regulator
GPX87_RS08130	COG2814	Major facilitator Superfamily
GPX87_RS08130	COG0477	Major facilitator Superfamily
GPX87_RS08135	COG2115	Belongs to the xylose isomerase family
GPX87_RS08150	COG2731	YhcH YjgK YiaL family protein
GPX87_RS08155	COG0583	DNA-binding transcription factor activity
GPX87_RS08160	COG1902	pentaerythritol trinitrate reductase activity
GPX87_RS08170	COG0243	molybdopterin cofactor binding
GPX87_RS08175	COG0437	4 iron, 4 sulfur cluster binding
GPX87_RS08180	COG3302	dmso reductase anchor subunit
GPX87_RS08185	COG3381	protein complex oligomerization
GPX87_RS08200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPX87_RS08245	COG0328	RNA-DNA hybrid ribonuclease activity
GPX87_RS08255	COG2188	Transcriptional regulator
GPX87_RS08260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX87_RS08260	COG1263	PTS System
GPX87_RS08265	COG1486	melibiose metabolic process
GPX87_RS08270	COG1929	Belongs to the glycerate kinase type-1 family
GPX87_RS08325	COG3609	addiction module antidote protein, CC2985 family
GPX87_RS08365	COG0251	oxidation-reduction process
GPX87_RS08370	COG3048	D-serine ammonia-lyase activity
GPX87_RS08375	COG2610	gluconate transmembrane transporter activity
GPX87_RS08380	COG0583	DNA-binding transcription factor activity
GPX87_RS08400	COG2003	Belongs to the UPF0758 family
GPX87_RS08410	COG1943	Transposase
GPX87_RS08430	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GPX87_RS08440	COG0582	viral genome integration into host DNA
GPX87_RS08510	COG3550	peptidyl-serine autophosphorylation
GPX87_RS08515	COG3550	peptidyl-serine autophosphorylation
GPX87_RS08535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPX87_RS08540	COG0358	DNA primase activity
GPX87_RS08545	COG1610	YqeY-like protein
GPX87_RS08555	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPX87_RS08560	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GPX87_RS08565	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPX87_RS08570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPX87_RS08585	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPX87_RS08595	COG0585	pseudouridine synthase activity
GPX87_RS08600	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GPX87_RS08610	COG1388	LysM domain
GPX87_RS08610	COG4942	peptidase
GPX87_RS08615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPX87_RS08620	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPX87_RS08640	COG4208	sulfate ABC transporter
GPX87_RS08645	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GPX87_RS08650	COG1546	Belongs to the CinA family
GPX87_RS08655	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPX87_RS08665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPX87_RS08670	COG0527	aspartate kinase activity
GPX87_RS08720	COG3630	sodium ion export across plasma membrane
GPX87_RS08725	COG0511	ligase activity, forming carbon-carbon bonds
GPX87_RS08725	COG5016	pyruvate
GPX87_RS08730	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPX87_RS08735	COG1063	alcohol dehydrogenase
GPX87_RS08740	COG1238	metal cluster binding
GPX87_RS08745	COG0612	Peptidase, M16
GPX87_RS08750	COG2918	glutathione biosynthetic process
GPX87_RS08755	COG1854	S-ribosylhomocysteine lyase activity
GPX87_RS08760	COG4536	flavin adenine dinucleotide binding
GPX87_RS08765	COG4137	Cytochrome C assembly protein
GPX87_RS08770	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPX87_RS08775	COG0228	four-way junction DNA binding
GPX87_RS08780	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPX87_RS08785	COG0336	Belongs to the RNA methyltransferase TrmD family
GPX87_RS08790	COG0335	large ribosomal subunit rRNA binding
GPX87_RS08795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPX87_RS08800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPX87_RS08810	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GPX87_RS08815	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPX87_RS08820	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GPX87_RS08825	COG0723	plastoquinol--plastocyanin reductase activity
GPX87_RS08830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GPX87_RS08835	COG2857	Cytochrome c1
GPX87_RS08840	COG0625	glutathione transferase activity
GPX87_RS08845	COG2969	positive regulation of protein catabolic process
GPX87_RS08850	COG2823	Periplasmic or secreted lipoprotein
GPX87_RS08855	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPX87_RS08860	COG0792	nuclease activity
GPX87_RS08865	COG3107	peptidoglycan biosynthetic process
GPX87_RS08870	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPX87_RS08885	COG3116	cell division
GPX87_RS08890	COG0768	penicillin binding
GPX87_RS08895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPX87_RS08900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GPX87_RS08905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPX87_RS08910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPX87_RS08915	COG0772	Belongs to the SEDS family
GPX87_RS08920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPX87_RS08925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPX87_RS08930	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GPX87_RS08935	COG0849	cell division
GPX87_RS08940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPX87_RS08945	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GPX87_RS08950	COG0653	protein targeting
GPX87_RS08955	COG0494	nUDIX hydrolase
GPX87_RS08965	COG0505	Belongs to the CarA family
GPX87_RS08970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GPX87_RS08995	COG2860	membrane
GPX87_RS09000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPX87_RS09010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPX87_RS09020	COG0067	glutamate synthase
GPX87_RS09020	COG0069	glutamate synthase activity
GPX87_RS09020	COG0070	glutamate synthase
GPX87_RS09025	COG1242	4 iron, 4 sulfur cluster binding
GPX87_RS09030	COG5002	protein histidine kinase activity
GPX87_RS09030	COG2198	Histidine kinase
GPX87_RS09030	COG0784	Response regulator, receiver
GPX87_RS09040	COG0745	RESPONSE REGULATOR receiver
GPX87_RS09055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPX87_RS09075	COG0083	homoserine kinase activity
GPX87_RS09080	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPX87_RS09095	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPX87_RS09110	COG1115	amino acid carrier protein
GPX87_RS09125	COG0084	hydrolase, TatD family'
GPX87_RS09130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPX87_RS09140	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GPX87_RS09145	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPX87_RS09150	COG0813	purine-nucleoside phosphorylase activity
GPX87_RS09160	COG0560	Phosphoserine phosphatase
GPX87_RS09170	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPX87_RS09175	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPX87_RS09180	COG1022	Amp-dependent synthetase and ligase
GPX87_RS09190	COG2059	Chromate
GPX87_RS09200	COG0569	domain protein
GPX87_RS09200	COG0189	ligase activity
GPX87_RS09215	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPX87_RS09220	COG2171	N-acyltransferase activity
GPX87_RS09225	COG3141	response to X-ray
GPX87_RS09230	COG0583	DNA-binding transcription factor activity
GPX87_RS09240	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GPX87_RS09245	COG1074	ATP-dependent DNA helicase activity
GPX87_RS09250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GPX87_RS09260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPX87_RS09260	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPX87_RS09270	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GPX87_RS09275	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GPX87_RS09280	COG2166	iron-sulfur cluster assembly
GPX87_RS09285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPX87_RS09290	COG0693	protein deglycase activity
GPX87_RS09295	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPX87_RS09300	COG0737	Belongs to the 5'-nucleotidase family
GPX87_RS09305	COG3248	Nucleoside-binding outer membrane protein
GPX87_RS09325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPX87_RS09335	COG2974	May be involved in recombination
GPX87_RS09340	COG0745	RESPONSE REGULATOR receiver
GPX87_RS09345	COG5002	protein histidine kinase activity
GPX87_RS09355	COG0248	Ppx GppA phosphatase
GPX87_RS09360	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GPX87_RS09365	COG0573	inorganic phosphate transmembrane transporter activity
GPX87_RS09370	COG0581	inorganic phosphate transmembrane transporter activity
GPX87_RS09375	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPX87_RS09380	COG0704	Plays a role in the regulation of phosphate uptake
GPX87_RS09390	COG0450	alkyl hydroperoxide reductase
GPX87_RS09395	COG0583	DNA-binding transcription factor activity
GPX87_RS09400	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GPX87_RS09410	COG0517	IMP dehydrogenase activity
GPX87_RS09415	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPX87_RS09420	COG0343	queuine tRNA-ribosyltransferase activity
GPX87_RS09425	COG1862	Preprotein translocase
GPX87_RS09430	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPX87_RS09435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPX87_RS09440	COG0483	inositol monophosphate 1-phosphatase activity
GPX87_RS09450	COG1959	2 iron, 2 sulfur cluster binding
GPX87_RS09460	COG0822	iron-sulfur transferase activity
GPX87_RS09470	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPX87_RS09480	COG0633	Ferredoxin
GPX87_RS09485	COG2975	iron-sulfur cluster assembly
GPX87_RS09490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPX87_RS09500	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GPX87_RS09505	COG1426	Protein conserved in bacteria
GPX87_RS09510	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GPX87_RS09515	COG0124	histidyl-tRNA synthetase
GPX87_RS09520	COG2976	Protein conserved in bacteria
GPX87_RS09525	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPX87_RS09530	COG1160	GTP binding
GPX87_RS09540	COG1570	exodeoxyribonuclease VII activity
GPX87_RS09545	COG0516	GMP reductase activity
GPX87_RS09545	COG0517	IMP dehydrogenase activity
GPX87_RS09560	COG0667	Aldo Keto reductase
GPX87_RS09600	COG1584	GPR1 FUN34 yaaH family protein
GPX87_RS09605	COG1115	amino acid carrier protein
GPX87_RS09620	COG2239	Acts as a magnesium transporter
GPX87_RS09625	COG4628	conserved protein (DUF2132)
GPX87_RS09645	COG1464	Belongs to the NlpA lipoprotein family
GPX87_RS09650	COG0243	molybdopterin cofactor binding
GPX87_RS09655	COG0437	4 iron, 4 sulfur cluster binding
GPX87_RS09660	COG3302	dmso reductase anchor subunit
GPX87_RS09665	COG3381	protein complex oligomerization
GPX87_RS09675	COG1609	Transcriptional regulator
GPX87_RS09680	COG2723	6-phospho-beta-galactosidase activity
GPX87_RS09690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX87_RS09690	COG2190	(PTS) system
GPX87_RS09690	COG1263	PTS System
GPX87_RS09700	COG1609	Transcriptional regulator
GPX87_RS09720	COG2723	6-phospho-beta-galactosidase activity
GPX87_RS09730	COG3459	Glycosyltransferase 36 associated
GPX87_RS09735	COG2017	converts alpha-aldose to the beta-anomer
GPX87_RS09745	COG1609	Transcriptional regulator
GPX87_RS09805	COG0328	RNA-DNA hybrid ribonuclease activity
GPX87_RS09820	COG2003	Belongs to the UPF0758 family
GPX87_RS09835	COG3335	DDE superfamily endonuclease
GPX87_RS09850	COG0514	ATP-dependent DNA helicase (RecQ)
GPX87_RS09875	COG1715	Restriction endonuclease
GPX87_RS09880	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GPX87_RS09885	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GPX87_RS09895	COG1196	nuclear chromosome segregation
GPX87_RS09905	COG0582	viral genome integration into host DNA
GPX87_RS09915	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GPX87_RS09920	COG2867	negative regulation of translational initiation
GPX87_RS09925	COG2914	Belongs to the UPF0125 (RnfH) family
GPX87_RS09930	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPX87_RS09935	COG0497	DNA recombination
GPX87_RS09940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPX87_RS09945	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPX87_RS09950	COG0443	Heat shock 70 kDa protein
GPX87_RS09955	COG0484	heat shock protein binding
GPX87_RS09985	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPX87_RS10005	COG1012	belongs to the aldehyde dehydrogenase family
GPX87_RS10005	COG2030	dehydratase
GPX87_RS10010	COG3396	Phenylacetate-CoA oxygenase
GPX87_RS10015	COG3460	Phenylacetate-CoA oxygenase
GPX87_RS10020	COG3396	Phenylacetate-CoA oxygenase
GPX87_RS10025	COG2151	metal-sulfur cluster biosynthetic enzyme
GPX87_RS10030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPX87_RS10035	COG1024	Enoyl-CoA hydratase
GPX87_RS10040	COG1024	Enoyl-CoA hydratase
GPX87_RS10045	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPX87_RS10050	COG2050	protein possibly involved in aromatic compounds catabolism
GPX87_RS10055	COG0183	Belongs to the thiolase family
GPX87_RS10060	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GPX87_RS10065	COG3327	negative regulation of DNA-templated transcription, initiation
GPX87_RS10075	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GPX87_RS10085	COG0583	DNA-binding transcription factor activity
GPX87_RS10090	COG0590	tRNA wobble adenosine to inosine editing
GPX87_RS10095	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GPX87_RS10115	COG0442	prolyl-tRNA aminoacylation
GPX87_RS10120	COG1720	tRNA m6t6A37 methyltransferase activity
GPX87_RS10130	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GPX87_RS10165	COG3098	single-species biofilm formation
GPX87_RS10170	COG0564	pseudouridine synthase activity
GPX87_RS10175	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPX87_RS10180	COG0142	geranyltranstransferase activity
GPX87_RS10185	COG1722	exodeoxyribonuclease VII activity
GPX87_RS10190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPX87_RS10200	COG0301	tRNA thio-modification
GPX87_RS10200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPX87_RS10205	COG0583	DNA-binding transcription factor activity
GPX87_RS10215	COG2363	Small membrane protein
GPX87_RS10225	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPX87_RS10230	COG1611	Belongs to the LOG family
GPX87_RS10235	COG3706	GGDEF domain
GPX87_RS10235	COG0745	RESPONSE REGULATOR receiver
GPX87_RS10245	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPX87_RS10245	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPX87_RS10255	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GPX87_RS10260	COG1464	Belongs to the NlpA lipoprotein family
GPX87_RS10265	COG2011	ABC-type metal ion transport system permease component
GPX87_RS10270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPX87_RS10275	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPX87_RS10280	COG1609	Transcriptional regulator
GPX87_RS10285	COG1263	PTS System
GPX87_RS10285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX87_RS10290	COG0366	Alpha amylase catalytic
GPX87_RS10320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPX87_RS10360	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GPX87_RS10370	COG2921	Belongs to the UPF0250 family
GPX87_RS10375	COG1686	Belongs to the peptidase S11 family
GPX87_RS10380	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPX87_RS10385	COG0772	Belongs to the SEDS family
GPX87_RS10390	COG0768	penicillin binding
GPX87_RS10395	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPX87_RS10400	COG0799	negative regulation of ribosome biogenesis
GPX87_RS10405	COG1466	dna polymerase III delta subunit
GPX87_RS10410	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GPX87_RS10415	COG0495	leucyl-tRNA aminoacylation
GPX87_RS10420	COG2888	peptidyl-tyrosine sulfation
GPX87_RS10425	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GPX87_RS10430	COG4535	Mg2 and Co2 transporter CorC
GPX87_RS10435	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPX87_RS10440	COG1702	phosphate starvation-inducible protein PhoH
GPX87_RS10445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPX87_RS10450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPX87_RS10455	COG2190	(PTS) system
GPX87_RS10465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX87_RS10475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPX87_RS10480	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GPX87_RS10485	COG3115	cell septum assembly
GPX87_RS10490	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPX87_RS10505	COG0789	Transcriptional regulator
GPX87_RS10510	COG1585	Membrane protein implicated in regulation of membrane protease activity
GPX87_RS10515	COG0330	HflC and HflK could
GPX87_RS10520	COG3118	belongs to the thioredoxin family
GPX87_RS10525	COG0300	oxidoreductase activity
GPX87_RS10530	COG1090	epimerase
GPX87_RS10535	COG0622	Phosphoesterase
GPX87_RS10545	COG3710	Transcriptional regulator
GPX87_RS10550	COG0326	Molecular chaperone. Has ATPase activity
GPX87_RS10560	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GPX87_RS10570	COG0250	Participates in transcription elongation, termination and antitermination
GPX87_RS10575	COG0367	asparagine synthase
GPX87_RS10580	COG4651	solute:proton antiporter activity
GPX87_RS10580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPX87_RS10585	COG1846	Transcriptional regulator
GPX87_RS10585	COG1940	carbohydrate kinase activity
GPX87_RS10590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPX87_RS10595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX87_RS10595	COG2190	(PTS) system
GPX87_RS10595	COG1263	PTS System
GPX87_RS10600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPX87_RS10610	COG0101	tRNA pseudouridine synthase activity
GPX87_RS10615	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPX87_RS10620	COG0285	dihydrofolate synthase activity
GPX87_RS10625	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GPX87_RS10630	COG1286	toxin biosynthetic process
GPX87_RS10635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPX87_RS10640	COG2056	Na+-H+ antiporter family
GPX87_RS10655	COG0346	lactoylglutathione lyase activity
GPX87_RS10660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPX87_RS10670	COG4659	FMN binding
GPX87_RS10675	COG4658	electron transport chain
GPX87_RS10680	COG4656	Part of a membrane complex involved in electron transport
GPX87_RS10685	COG2878	Part of a membrane complex involved in electron transport
GPX87_RS10690	COG4657	Part of a membrane complex involved in electron transport
GPX87_RS10695	COG0840	transmembrane signaling receptor activity
GPX87_RS10710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPX87_RS10710	COG3153	acetyltransferase
GPX87_RS10720	COG2985	domain, Protein
GPX87_RS10725	COG1760	l-serine dehydratase
GPX87_RS10730	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GPX87_RS10735	COG0544	peptidyl-prolyl cis-trans isomerase activity
GPX87_RS10745	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPX87_RS10750	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPX87_RS10755	COG0776	regulation of translation
GPX87_RS10760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPX87_RS10770	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GPX87_RS10775	COG0539	negative regulation of cytoplasmic translation
GPX87_RS10785	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GPX87_RS10790	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GPX87_RS10810	COG0583	DNA-binding transcription factor activity
GPX87_RS10820	COG0686	Belongs to the AlaDH PNT family
GPX87_RS10825	COG1522	sequence-specific DNA binding
GPX87_RS10830	COG1674	ftsk spoiiie
GPX87_RS10850	COG2186	Transcriptional regulator
GPX87_RS10860	COG0840	transmembrane signaling receptor activity
GPX87_RS10865	COG0537	adenosine 5'-monophosphoramidase activity
GPX87_RS10895	COG1252	NADH dehydrogenase
GPX87_RS10900	COG1021	2,3-dihydroxybenzoate-AMP ligase
GPX87_RS10905	COG1169	isochorismate synthase
GPX87_RS10910	COG1028	Short-chain dehydrogenase reductase Sdr
GPX87_RS10915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPX87_RS10920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPX87_RS10920	COG3433	isochorismatase activity
GPX87_RS10920	COG2226	methyltransferase
GPX87_RS10940	COG4592	Periplasmic binding protein
GPX87_RS10945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPX87_RS10950	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPX87_RS10955	COG1629	transport
GPX87_RS10955	COG4774	siderophore transport
GPX87_RS10965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPX87_RS10970	COG1120	ATPase activity
GPX87_RS10980	COG2366	antibiotic biosynthetic process
GPX87_RS11000	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPX87_RS11010	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPX87_RS11015	COG1136	(ABC) transporter
GPX87_RS11020	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPX87_RS11025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPX87_RS11025	COG0475	glutathione-regulated potassium exporter activity
GPX87_RS11030	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPX87_RS11040	COG0658	competence protein
GPX87_RS11040	COG2333	competence protein COMEC
GPX87_RS11045	COG1132	(ABC) transporter
GPX87_RS11050	COG1663	tetraacyldisaccharide 4'-kinase activity
GPX87_RS11060	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GPX87_RS11065	COG2719	SpoVR family
GPX87_RS11070	COG2718	Belongs to the UPF0229 family
GPX87_RS11075	COG2766	serine protein kinase
GPX87_RS11085	COG3013	Belongs to the UPF0304 family
GPX87_RS11090	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPX87_RS11095	COG1882	Formate acetyltransferase
GPX87_RS11115	COG4215	(ABC) transporter
GPX87_RS11125	COG0708	Exodeoxyribonuclease III
GPX87_RS11145	COG0730	response to heat
GPX87_RS11150	COG1199	ATP-dependent helicase activity
GPX87_RS11160	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPX87_RS11170	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPX87_RS11175	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPX87_RS11180	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPX87_RS11185	COG0215	cysteine-tRNA ligase activity
GPX87_RS11190	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GPX87_RS11195	COG0632	four-way junction helicase activity
GPX87_RS11200	COG2255	four-way junction helicase activity
GPX87_RS11205	COG1271	oxidase subunit
GPX87_RS11210	COG1294	oxidase, subunit
GPX87_RS11215	COG4890	Cyd operon protein YbgT
GPX87_RS11225	COG0824	Thioesterase
GPX87_RS11230	COG0811	peptide transport
GPX87_RS11250	COG2885	chlorophyll binding
GPX87_RS11255	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GPX87_RS11260	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GPX87_RS11275	COG2188	Transcriptional regulator
GPX87_RS11280	COG1486	melibiose metabolic process
GPX87_RS11285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX87_RS11285	COG1263	PTS System
GPX87_RS11290	COG1349	DNA-binding transcription factor activity
GPX87_RS11300	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPX87_RS11305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPX87_RS11440	COG4657	Part of a membrane complex involved in electron transport
GPX87_RS11445	COG2878	Part of a membrane complex involved in electron transport
GPX87_RS11490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPX87_RS11495	COG1115	amino acid carrier protein
GPX87_RS11510	COG4948	Mandelate Racemase Muconate Lactonizing
GPX87_RS11520	COG0531	amino acid
GPX87_RS11530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPX87_RS11540	COG4139	cobalamin transport
GPX87_RS11555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPX87_RS11565	COG0659	secondary active sulfate transmembrane transporter activity
GPX87_RS11570	COG0640	Transcriptional regulator
GPX87_RS11610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPX87_RS11620	COG0573	inorganic phosphate transmembrane transporter activity
GPX87_RS11630	COG0640	Transcriptional regulator
GPX87_RS11635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPX87_RS11655	COG1012	belongs to the aldehyde dehydrogenase family
GPX87_RS11675	COG1960	acyl-CoA dehydrogenase activity
GPX87_RS11680	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPX87_RS11690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPX87_RS11700	COG1737	Transcriptional regulator
GPX87_RS11705	COG0076	glutamate decarboxylase activity
GPX87_RS11715	COG2431	L-lysine efflux transmembrane transporter activity
GPX87_RS11725	COG3070	regulator of competence-specific genes
GPX87_RS11740	COG3852	Histidine kinase
GPX87_RS11750	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPX87_RS11760	COG1032	radical SAM domain protein
GPX87_RS11770	COG0612	Peptidase, M16
GPX87_RS11785	COG0583	DNA-binding transcription factor activity
GPX87_RS11790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPX87_RS11800	COG2350	Protein conserved in bacteria
GPX87_RS11805	COG1607	acyl-coa hydrolase
GPX87_RS11820	COG0159	tryptophan synthase activity
GPX87_RS11825	COG0133	tryptophan synthase activity
GPX87_RS11830	COG0134	indole-3-glycerol-phosphate synthase activity
GPX87_RS11830	COG0135	phosphoribosylanthranilate isomerase activity
GPX87_RS11835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPX87_RS11840	COG0512	Glutamine amidotransferase of anthranilate synthase
GPX87_RS11845	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPX87_RS11855	COG0613	PHP domain protein
GPX87_RS11860	COG0009	L-threonylcarbamoyladenylate synthase
GPX87_RS11865	COG1187	pseudouridine synthase activity
GPX87_RS11875	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GPX87_RS11880	COG4988	ABC transporter
GPX87_RS11885	COG0492	ferredoxin-NADP+ reductase activity
GPX87_RS11905	COG2949	membrane
GPX87_RS11915	COG0281	malic enzyme
GPX87_RS11920	COG1643	Atp-dependent helicase
GPX87_RS11930	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GPX87_RS11950	COG2885	chlorophyll binding
GPX87_RS11965	COG0247	lactate metabolic process
GPX87_RS11965	COG0277	FAD linked oxidase domain protein
GPX87_RS11985	COG3099	Belongs to the UPF0263 family
GPX87_RS11990	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPX87_RS12000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPX87_RS12005	COG0417	DNA replication proofreading
GPX87_RS12020	COG2197	response regulator
GPX87_RS12025	COG0322	excinuclease ABC activity
GPX87_RS12035	COG1278	Cold shock
GPX87_RS12040	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GPX87_RS12045	COG0542	response to heat
GPX87_RS12050	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPX87_RS12055	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GPX87_RS12060	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GPX87_RS12065	COG3134	Outer membrane lipoprotein
GPX87_RS12070	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GPX87_RS12080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPX87_RS12085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPX87_RS12090	COG0297	glycogen (starch) synthase activity
GPX87_RS12100	COG3070	regulator of competence-specific genes
GPX87_RS12105	COG1609	Transcriptional regulator
GPX87_RS12110	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPX87_RS12115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPX87_RS12120	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GPX87_RS12125	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GPX87_RS12130	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GPX87_RS12135	COG0189	ligase activity
GPX87_RS12145	COG4067	protein conserved in archaea
GPX87_RS12145	COG0189	ligase activity
GPX87_RS12150	COG0500	methyltransferase
GPX87_RS12155	COG4106	trans-aconitate 2-methyltransferase activity
GPX87_RS12160	COG1801	Protein of unknown function DUF72
GPX87_RS12170	COG1435	thymidine kinase activity
GPX87_RS12175	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPX87_RS12180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPX87_RS12190	COG2116	formate transmembrane transporter activity
GPX87_RS12195	COG1227	inorganic diphosphatase activity
GPX87_RS12205	COG4172	Belongs to the ABC transporter superfamily
GPX87_RS12215	COG4171	peptide transport system, permease
GPX87_RS12220	COG4168	peptide transport system, permease
GPX87_RS12230	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GPX87_RS12235	COG1842	Phage shock protein A
GPX87_RS12245	COG1983	PspC domain protein
GPX87_RS12250	COG0519	Catalyzes the synthesis of GMP from XMP
GPX87_RS12255	COG0626	cystathionine gamma-synthase activity
GPX87_RS12265	COG0733	neurotransmitter:sodium symporter activity
GPX87_RS12270	COG0564	pseudouridine synthase activity
GPX87_RS12275	COG0116	Belongs to the methyltransferase superfamily
GPX87_RS12275	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPX87_RS12285	COG3313	Fe-S protein
GPX87_RS12295	COG0814	amino acid
GPX87_RS12305	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPX87_RS12315	COG2076	Multidrug Resistance protein
GPX87_RS12320	COG1278	Cold shock
GPX87_RS12330	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPX87_RS12330	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPX87_RS12345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GPX87_RS12370	COG0546	phosphoglycolate phosphatase activity
GPX87_RS12385	COG0484	heat shock protein binding
GPX87_RS12395	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPX87_RS12405	COG4181	ATPase activity
GPX87_RS12410	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GPX87_RS12425	COG1984	allophanate hydrolase subunit 2
GPX87_RS12430	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GPX87_RS12435	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GPX87_RS12440	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPX87_RS12445	COG0840	transmembrane signaling receptor activity
GPX87_RS12450	COG0814	amino acid
GPX87_RS12455	COG0513	Belongs to the DEAD box helicase family
GPX87_RS12460	COG1309	transcriptional regulator
GPX87_RS12465	COG1414	Transcriptional regulator
GPX87_RS12480	COG1012	belongs to the aldehyde dehydrogenase family
GPX87_RS12485	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GPX87_RS12490	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GPX87_RS12500	COG0183	Belongs to the thiolase family
GPX87_RS12510	COG0494	nUDIX hydrolase
GPX87_RS12520	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GPX87_RS12560	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPX87_RS12575	COG0450	alkyl hydroperoxide reductase
GPX87_RS12590	COG0640	Transcriptional regulator
GPX87_RS12605	COG1328	CTP reductase activity
GPX87_RS12610	COG0602	queuosine metabolic process
GPX87_RS12620	COG0189	ligase activity
GPX87_RS12620	COG4067	protein conserved in archaea
GPX87_RS12625	COG3706	GGDEF domain
GPX87_RS12640	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GPX87_RS12645	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GPX87_RS12655	COG0745	RESPONSE REGULATOR receiver
GPX87_RS12675	COG2873	o-acetylhomoserine
GPX87_RS12730	COG2205	protein histidine kinase activity
GPX87_RS12730	COG0784	Response regulator, receiver
GPX87_RS12745	COG3278	Belongs to the heme-copper respiratory oxidase family
GPX87_RS12760	COG2010	Cytochrome c
GPX87_RS12770	COG2217	Heavy metal translocating P-type atpase
GPX87_RS12785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPX87_RS12790	COG0589	response to stress
GPX87_RS12815	COG3842	ATPase activity
GPX87_RS12820	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPX87_RS12825	COG1177	transmembrane transport
GPX87_RS12830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPX87_RS12835	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPX87_RS12840	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GPX87_RS12855	COG0437	4 iron, 4 sulfur cluster binding
GPX87_RS12860	COG0243	molybdopterin cofactor binding
GPX87_RS12860	COG3383	formate dehydrogenase (NAD+) activity
GPX87_RS12890	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPX87_RS12895	COG3852	Histidine kinase
GPX87_RS12900	COG2204	response regulator
GPX87_RS12910	COG4662	Binding-protein-dependent transport system inner membrane component
GPX87_RS12915	COG1136	(ABC) transporter
GPX87_RS12920	COG0746	molybdenum cofactor guanylyltransferase activity
GPX87_RS12925	COG3108	Peptidase M15
GPX87_RS12930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPX87_RS12945	COG1846	Transcriptional regulator
GPX87_RS12950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPX87_RS12955	COG0840	transmembrane signaling receptor activity
GPX87_RS12960	COG2176	DNA-directed DNA polymerase activity
GPX87_RS12965	COG0517	IMP dehydrogenase activity
GPX87_RS12970	COG1448	Aminotransferase
GPX87_RS12980	COG0720	synthase
GPX87_RS12990	COG1136	(ABC) transporter
GPX87_RS12990	COG0577	efflux transmembrane transporter activity
GPX87_RS12995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPX87_RS13000	COG1760	l-serine dehydratase
GPX87_RS13005	COG0814	amino acid
GPX87_RS13010	COG0494	nUDIX hydrolase
GPX87_RS13015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPX87_RS13030	COG3106	COG3106 Predicted ATPase
GPX87_RS13040	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GPX87_RS13045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPX87_RS13055	COG5006	permease, DMT superfamily
GPX87_RS13070	COG0471	metal ion transport
GPX87_RS13075	COG4191	Histidine kinase
GPX87_RS13075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX87_RS13085	COG2991	Protein conserved in bacteria
GPX87_RS13100	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPX87_RS13105	COG0372	Belongs to the citrate synthase family
GPX87_RS13115	COG2828	Protein conserved in bacteria
GPX87_RS13140	COG0745	RESPONSE REGULATOR receiver
GPX87_RS13140	COG3706	GGDEF domain
GPX87_RS13145	COG1966	Carbon starvation protein
GPX87_RS13155	COG0003	Pfam Anion-transporting ATPase
GPX87_RS13165	COG1115	amino acid carrier protein
GPX87_RS13180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPX87_RS13185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPX87_RS13200	COG2996	Protein conserved in bacteria
GPX87_RS13205	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GPX87_RS13205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPX87_RS13210	COG3008	intermembrane lipid transfer
GPX87_RS13215	COG2995	paraquat-inducible protein a
GPX87_RS13220	COG1956	GAF domain-containing protein
GPX87_RS13225	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GPX87_RS13235	COG0308	aminopeptidase N
GPX87_RS13245	COG2902	Dehydrogenase
GPX87_RS13250	COG0167	dihydroorotate dehydrogenase activity
GPX87_RS13260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPX87_RS13260	COG0116	Belongs to the methyltransferase superfamily
GPX87_RS13270	COG0488	(ABC) transporter
GPX87_RS13285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPX87_RS13290	COG1067	ATP-dependent peptidase activity
GPX87_RS13295	COG3120	sequence-specific DNA binding
GPX87_RS13310	COG0023	Translation Initiation Factor
GPX87_RS13320	COG1181	Belongs to the D-alanine--D-alanine ligase family
GPX87_RS13330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPX87_RS13330	COG0045	succinate-CoA ligase (ADP-forming) activity
GPX87_RS13330	COG1042	CoA-binding domain protein
GPX87_RS13335	COG0583	DNA-binding transcription factor activity
GPX87_RS13340	COG4533	DNA binding
GPX87_RS13350	COG2050	protein possibly involved in aromatic compounds catabolism
GPX87_RS13360	COG2824	Alkylphosphonate utilization operon protein PhnA
GPX87_RS13370	COG0861	Integral membrane protein TerC family
GPX87_RS13375	COG0737	Belongs to the 5'-nucleotidase family
GPX87_RS13380	COG3593	DNA synthesis involved in DNA repair
GPX87_RS13390	COG0583	DNA-binding transcription factor activity
GPX87_RS13395	COG2116	formate transmembrane transporter activity
GPX87_RS13405	COG3038	cytochrome b561
GPX87_RS13415	COG0517	IMP dehydrogenase activity
GPX87_RS13430	COG0673	inositol 2-dehydrogenase activity
GPX87_RS13435	COG2610	gluconate transmembrane transporter activity
GPX87_RS13440	COG1454	alcohol dehydrogenase
GPX87_RS13450	COG0840	transmembrane signaling receptor activity
GPX87_RS13465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPX87_RS13470	COG3962	Belongs to the TPP enzyme family
GPX87_RS13475	COG3718	enzyme involved in inositol metabolism
GPX87_RS13485	COG2176	DNA-directed DNA polymerase activity
GPX87_RS13490	COG0517	IMP dehydrogenase activity
GPX87_RS13490	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GPX87_RS13495	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPX87_RS13500	COG0673	inositol 2-dehydrogenase activity
GPX87_RS13505	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPX87_RS13510	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPX87_RS13515	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPX87_RS13520	COG1129	ABC transporter
GPX87_RS13530	COG0488	(ABC) transporter
GPX87_RS13575	COG0765	amino acid transport
GPX87_RS13580	COG0765	amino acid transport
GPX87_RS13595	COG0582	viral genome integration into host DNA
GPX87_RS13620	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPX87_RS13640	COG2205	protein histidine kinase activity
GPX87_RS13645	COG0745	RESPONSE REGULATOR receiver
GPX87_RS13675	COG0789	Transcriptional regulator
GPX87_RS13725	COG2003	Belongs to the UPF0758 family
GPX87_RS13765	COG0328	RNA-DNA hybrid ribonuclease activity
GPX87_RS13780	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPX87_RS13785	COG0523	cobalamin synthesis protein
GPX87_RS13790	COG0038	chloride channel
GPX87_RS13810	COG0156	8-amino-7-oxononanoate synthase activity
GPX87_RS13815	COG0784	Response regulator, receiver
GPX87_RS13815	COG2205	protein histidine kinase activity
GPX87_RS13820	COG0419	ATPase involved in DNA repair
GPX87_RS13825	COG0420	3'-5' exonuclease activity
GPX87_RS13830	COG1609	Transcriptional regulator
GPX87_RS13835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX87_RS13835	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX87_RS13840	COG1105	Belongs to the carbohydrate kinase PfkB family
GPX87_RS13845	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GPX87_RS13845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX87_RS13845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX87_RS13850	COG1609	Transcriptional regulator
GPX87_RS13855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX87_RS13875	COG0589	response to stress
GPX87_RS13880	COG2501	S4 domain
GPX87_RS13890	COG4172	Belongs to the ABC transporter superfamily
GPX87_RS13895	COG4239	(ABC) transporter, permease
GPX87_RS13900	COG4174	ABC transporter (Permease)
GPX87_RS13905	COG4166	transmembrane transport
GPX87_RS13910	COG0494	nUDIX hydrolase
GPX87_RS13925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPX87_RS13930	COG1011	Hydrolase
GPX87_RS13935	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GPX87_RS13955	COG2897	thiosulfate sulfurtransferase activity
GPX87_RS13960	COG3738	Protein conserved in bacteria
GPX87_RS13995	COG5433	transposase activity
GPX87_RS14005	COG0346	lactoylglutathione lyase activity
GPX87_RS14010	COG3335	DDE superfamily endonuclease
GPX87_RS14015	COG0346	lactoylglutathione lyase activity
GPX87_RS14025	COG2801	Transposase and inactivated derivatives
GPX87_RS14115	COG2801	Transposase and inactivated derivatives
GPX87_RS14180	COG0582	viral genome integration into host DNA
GPX87_RS14200	COG1204	response to ionizing radiation
GPX87_RS14230	COG0582	viral genome integration into host DNA
GPX87_RS14235	COG5433	transposase activity
GPX87_RS14315	COG2801	Transposase and inactivated derivatives
GPX87_RS14365	COG2801	Transposase and inactivated derivatives
GPX87_RS14405	COG0242	peptide deformylase activity
GPX87_RS14435	COG2801	Transposase and inactivated derivatives
GPX87_RS14490	COG3179	chitinase
GPX87_RS14495	COG2801	Transposase and inactivated derivatives
GPX87_RS14535	COG2801	Transposase and inactivated derivatives
GPX87_RS14570	COG0454	-acetyltransferase
GPX87_RS14575	COG1028	Short-chain dehydrogenase reductase Sdr
GPX87_RS14580	COG5433	transposase activity
GPX87_RS14640	COG2801	Transposase and inactivated derivatives
GPX87_RS14655	COG5433	transposase activity
GPX87_RS14670	COG3041	Addiction module toxin RelE StbE family
GPX87_RS14690	COG2801	Transposase and inactivated derivatives
GPX87_RS14715	COG3335	DDE superfamily endonuclease
GPX87_RS14730	COG2801	Transposase and inactivated derivatives
GPX87_RS14790	COG2026	Addiction module toxin, RelE StbE family
GPX87_RS14825	COG5433	transposase activity
GPX87_RS14855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPX87_RS14860	COG0513	Belongs to the DEAD box helicase family
GPX87_RS14865	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GPX87_RS14910	COG2723	6-phospho-beta-galactosidase activity
GPX87_RS14925	COG1263	PTS System
GPX87_RS14925	COG2190	(PTS) system
GPX87_RS14925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX87_RS14930	COG1785	Belongs to the alkaline phosphatase family
GPX87_RS14945	COG0527	aspartate kinase activity
GPX87_RS14950	COG0662	Cupin 2, conserved barrel domain protein
GPX87_RS14955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPX87_RS14960	COG0456	acetyltransferase
GPX87_RS14965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPX87_RS14985	COG1765	OsmC-like protein
GPX87_RS15000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPX87_RS15020	COG1522	sequence-specific DNA binding
GPX87_RS15025	COG0531	amino acid
GPX87_RS15030	COG0625	glutathione transferase activity
GPX87_RS15035	COG1278	Cold shock
GPX87_RS15045	COG4145	pantothenate transmembrane transporter activity
GPX87_RS15065	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GPX87_RS15085	COG0840	transmembrane signaling receptor activity
GPX87_RS15090	COG1482	cell wall glycoprotein biosynthetic process
GPX87_RS15095	COG0840	transmembrane signaling receptor activity
GPX87_RS15100	COG4580	involved in the transport of maltose and maltodextrins
GPX87_RS15105	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GPX87_RS15110	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GPX87_RS15120	COG1609	Transcriptional regulator
GPX87_RS15140	COG0395	ABC-type sugar transport system, permease component
GPX87_RS15145	COG1175	transmembrane transport
GPX87_RS15195	COG0633	Ferredoxin
GPX87_RS15195	COG3217	Mosc domain protein beta barrel domain protein
GPX87_RS15200	COG0418	dihydroorotase activity
GPX87_RS15215	COG1349	DNA-binding transcription factor activity
GPX87_RS15245	COG1175	transmembrane transport
GPX87_RS15255	COG3842	ATPase activity
GPX87_RS15260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPX87_RS15275	COG1461	Dihydroxyacetone kinase
GPX87_RS15280	COG2376	Dihydroxyacetone kinase
GPX87_RS15300	COG1063	alcohol dehydrogenase
GPX87_RS15305	COG0156	8-amino-7-oxononanoate synthase activity
GPX87_RS15320	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPX87_RS15325	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPX87_RS15330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPX87_RS15335	COG0363	glucosamine-6-phosphate deaminase activity
GPX87_RS15340	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPX87_RS15350	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GPX87_RS15355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GPX87_RS15360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX87_RS15360	COG2205	protein histidine kinase activity
GPX87_RS15365	COG2197	response regulator
GPX87_RS15370	COG5001	Diguanylate cyclase
GPX87_RS15370	COG3706	GGDEF domain
GPX87_RS15370	COG4251	negative regulation of phosphorylation
GPX87_RS15370	COG2203	Gaf domain
GPX87_RS15420	COG0673	inositol 2-dehydrogenase activity
GPX87_RS15425	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPX87_RS15435	COG1120	ATPase activity
GPX87_RS15440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPX87_RS15445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPX87_RS15450	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GPX87_RS15455	COG4774	siderophore transport
GPX87_RS15470	COG1342	Belongs to the UPF0251 family
GPX87_RS15475	COG1846	Transcriptional regulator
GPX87_RS15480	COG1566	PFAM secretion protein HlyD family protein
GPX87_RS15490	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GPX87_RS15500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPX87_RS15505	COG2259	Doxx family
GPX87_RS15510	COG0786	glutamate:sodium symporter activity
GPX87_RS15515	COG0786	glutamate:sodium symporter activity
GPX87_RS15520	COG1388	LysM domain
GPX87_RS15520	COG1376	ErfK ybiS ycfS ynhG family protein
GPX87_RS15525	COG0415	Belongs to the DNA photolyase family
GPX87_RS15530	COG0789	Transcriptional regulator
GPX87_RS15535	COG3272	Protein of unknown function (DUF1722)
GPX87_RS15540	COG0813	purine-nucleoside phosphorylase activity
GPX87_RS15550	COG2909	trisaccharide binding
GPX87_RS15555	COG3706	GGDEF domain
GPX87_RS15570	COG1999	signal sequence binding
GPX87_RS15580	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GPX87_RS15605	COG4580	involved in the transport of maltose and maltodextrins
GPX87_RS15615	COG1132	(ABC) transporter
GPX87_RS15630	COG3383	formate dehydrogenase (NAD+) activity
GPX87_RS15635	COG0010	Belongs to the arginase family
GPX87_RS15650	COG0840	transmembrane signaling receptor activity
GPX87_RS15660	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPX87_RS15665	COG0471	metal ion transport
GPX87_RS15675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GPX87_RS15680	COG1640	4-alpha-glucanotransferase
GPX87_RS15685	COG0058	SHG alpha-glucan phosphorylase activity
GPX87_RS15690	COG2909	trisaccharide binding
GPX87_RS15705	COG2207	Transcriptional regulator
GPX87_RS15710	COG1454	alcohol dehydrogenase
GPX87_RS15720	COG0471	metal ion transport
GPX87_RS15725	COG2207	Transcriptional regulator
GPX87_RS15730	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPX87_RS15735	COG2184	nucleotidyltransferase activity
GPX87_RS15740	COG1444	tRNA N-acetyltransferase activity
GPX87_RS15745	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPX87_RS15775	COG0217	transcriptional regulatory protein
GPX87_RS15780	COG2084	Dehydrogenase
GPX87_RS15785	COG0745	RESPONSE REGULATOR receiver
GPX87_RS15785	COG3706	GGDEF domain
GPX87_RS15800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GPX87_RS15830	COG1943	Transposase
GPX87_RS15840	COG0840	transmembrane signaling receptor activity
GPX87_RS15845	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPX87_RS15850	COG0513	Belongs to the DEAD box helicase family
GPX87_RS15855	COG0583	DNA-binding transcription factor activity
GPX87_RS15860	COG2910	NAD(P)H-binding
GPX87_RS15865	COG3706	GGDEF domain
GPX87_RS15870	COG4628	conserved protein (DUF2132)
GPX87_RS15875	COG0095	Lipoate-protein ligase
GPX87_RS15880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPX87_RS15890	COG3722	fumarate hydratase activity
GPX87_RS15900	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX87_RS15900	COG2213	PTS system mannitol-specific
GPX87_RS15905	COG0739	heme binding
GPX87_RS15915	COG0564	pseudouridine synthase activity
GPX87_RS15935	COG1869	D-ribose catabolic process
GPX87_RS15940	COG1129	ABC transporter
GPX87_RS15945	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPX87_RS15950	COG1879	ABC-type sugar transport system periplasmic component
GPX87_RS15955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPX87_RS15960	COG1609	Transcriptional regulator
GPX87_RS15970	COG0583	DNA-binding transcription factor activity
GPX87_RS15980	COG3530	Putative quorum-sensing-regulated virulence factor
GPX87_RS16005	COG4771	TonB-dependent receptor
GPX87_RS16005	COG1629	transport
GPX87_RS16015	COG1278	Cold shock
GPX87_RS16025	COG0513	Belongs to the DEAD box helicase family
GPX87_RS16030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPX87_RS16040	COG3724	N-succinylarginine dihydrolase activity
GPX87_RS16060	COG2304	oxidoreductase activity
GPX87_RS16080	COG0714	Associated with various cellular activities
GPX87_RS16095	COG0366	Alpha amylase catalytic
GPX87_RS16100	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPX87_RS16110	COG3604	Transcriptional regulator
GPX87_RS16115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPX87_RS16115	COG1017	nitric oxide dioxygenase activity
GPX87_RS16120	COG1278	Cold shock
GPX87_RS16135	COG0745	RESPONSE REGULATOR receiver
GPX87_RS16145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GPX87_RS16145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPX87_RS16150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPX87_RS16175	COG3300	MHYT domain
GPX87_RS16175	COG5001	Diguanylate cyclase
GPX87_RS16180	COG2259	Doxx family
GPX87_RS16190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPX87_RS16210	COG2200	EAL domain
GPX87_RS16220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPX87_RS16230	COG0363	glucosamine-6-phosphate deaminase activity
GPX87_RS16255	COG0513	Belongs to the DEAD box helicase family
GPX87_RS16265	COG0659	secondary active sulfate transmembrane transporter activity
GPX87_RS16275	COG0739	heme binding
GPX87_RS16280	COG5001	Diguanylate cyclase
GPX87_RS16290	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPX87_RS16295	COG0179	Fumarylacetoacetate (FAA) hydrolase
GPX87_RS16320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPX87_RS16325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPX87_RS16340	COG0840	transmembrane signaling receptor activity
GPX87_RS16345	COG2200	EAL domain
GPX87_RS16355	COG1304	FMN binding
GPX87_RS16360	COG1620	l-lactate permease
GPX87_RS16365	COG0583	DNA-binding transcription factor activity
GPX87_RS16375	COG1067	ATP-dependent peptidase activity
GPX87_RS16385	COG3123	guanosine phosphorylase activity
GPX87_RS16390	COG1741	Belongs to the pirin family
GPX87_RS16415	COG3706	GGDEF domain
GPX87_RS16420	COG0835	chemotaxis
GPX87_RS16420	COG0784	Response regulator, receiver
GPX87_RS16425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPX87_RS16430	COG3047	cAMP biosynthetic process
GPX87_RS16440	COG4989	oxidoreductase activity
GPX87_RS16445	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPX87_RS16450	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GPX87_RS16455	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPX87_RS16465	COG2814	Major facilitator Superfamily
GPX87_RS16480	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPX87_RS16485	COG4605	iron ion homeostasis
GPX87_RS16490	COG4604	ABC transporter, ATP-binding protein
GPX87_RS16495	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPX87_RS16520	COG5002	protein histidine kinase activity
GPX87_RS16520	COG2205	protein histidine kinase activity
GPX87_RS16520	COG0784	Response regulator, receiver
GPX87_RS16525	COG2197	response regulator
GPX87_RS16550	COG2113	Glycine betaine
GPX87_RS16555	COG4176	ABC-type proline glycine betaine transport system permease component
GPX87_RS16560	COG4175	Glycine betaine
GPX87_RS16570	COG1166	arginine decarboxylase activity
GPX87_RS16575	COG0010	Belongs to the arginase family
GPX87_RS16580	COG1686	Belongs to the peptidase S11 family
GPX87_RS16625	COG3335	DDE superfamily endonuclease
GPX87_RS16650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPX87_RS16655	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPX87_RS16660	COG2146	nitrite reductase [NAD(P)H] activity
GPX87_RS16665	COG2116	formate transmembrane transporter activity
GPX87_RS16690	COG2814	Major facilitator Superfamily
GPX87_RS16705	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPX87_RS16720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPX87_RS16725	COG0625	glutathione transferase activity
GPX87_RS16730	COG0583	DNA-binding transcription factor activity
GPX87_RS16735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPX87_RS16740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPX87_RS16750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPX87_RS16760	COG1596	polysaccharide export
GPX87_RS16790	COG0297	glycogen (starch) synthase activity
GPX87_RS16790	COG0438	transferase activity, transferring glycosyl groups
GPX87_RS16805	COG0247	lactate metabolic process
GPX87_RS16810	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GPX87_RS16815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPX87_RS16820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPX87_RS16850	COG2827	Endonuclease containing a URI domain
GPX87_RS16865	COG0725	ABC transporter, periplasmic molybdate-binding protein
GPX87_RS16870	COG4149	molybdate abc transporter
GPX87_RS16875	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GPX87_RS16890	COG1289	transmembrane transporter activity
GPX87_RS16895	COG0210	DNA helicase
GPX87_RS16900	COG1335	isochorismatase
GPX87_RS16910	COG1803	Methylglyoxal synthase
GPX87_RS16915	COG1979	alcohol dehydrogenase
GPX87_RS16925	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPX87_RS16940	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPX87_RS16950	COG0840	transmembrane signaling receptor activity
GPX87_RS16955	COG0840	transmembrane signaling receptor activity
GPX87_RS16960	COG0437	4 iron, 4 sulfur cluster binding
GPX87_RS16965	COG0348	domain, Protein
GPX87_RS16975	COG3005	denitrification pathway
GPX87_RS16985	COG0243	molybdopterin cofactor binding
GPX87_RS17000	COG3850	Histidine kinase
GPX87_RS17005	COG2197	response regulator
GPX87_RS17010	COG3069	C4-dicarboxylate transmembrane transporter activity
GPX87_RS17020	COG0456	acetyltransferase
GPX87_RS17025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPX87_RS17040	COG2885	chlorophyll binding
GPX87_RS17040	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GPX87_RS17045	COG0840	transmembrane signaling receptor activity
GPX87_RS17050	COG0778	Nitroreductase
GPX87_RS17080	COG0515	serine threonine protein kinase
GPX87_RS17080	COG2815	serine threonine protein kinase
GPX87_RS17115	COG0631	protein serine/threonine phosphatase activity
GPX87_RS17170	COG3501	Rhs element vgr protein
GPX87_RS17185	COG3209	COG3209 Rhs family protein
GPX87_RS17235	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GPX87_RS17240	COG1061	Type III restriction enzyme res subunit
GPX87_RS17245	COG1187	pseudouridine synthase activity
GPX87_RS17250	COG2814	Major facilitator Superfamily
GPX87_RS17260	COG0702	epimerase
GPX87_RS17265	COG0534	Mate efflux family protein
GPX87_RS17270	COG4181	ATPase activity
GPX87_RS17295	COG2111	Na H antiporter
GPX87_RS17300	COG1006	Multisubunit Na H antiporter MnhC subunit
GPX87_RS17310	COG1863	multisubunit Na H antiporter MnhE subunit
GPX87_RS17315	COG2212	antiporter activity
GPX87_RS17320	COG1320	monovalent cation:proton antiporter activity
GPX87_RS17330	COG1748	Saccharopine dehydrogenase
GPX87_RS17365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPX87_RS17390	COG2989	Protein conserved in bacteria