locus-tag	class	description
ET948_RS00005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ET948_RS00010	COG2011	ABC-type metal ion transport system permease component
ET948_RS00015	COG1464	Belongs to the NlpA lipoprotein family
ET948_RS00020	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
ET948_RS00030	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ET948_RS00030	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ET948_RS00045	COG1611	Belongs to the LOG family
ET948_RS00050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ET948_RS00060	COG2363	Small membrane protein
ET948_RS00070	COG0583	DNA-binding transcription factor activity
ET948_RS00075	COG0301	tRNA thio-modification
ET948_RS00075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ET948_RS00085	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ET948_RS00090	COG1722	exodeoxyribonuclease VII activity
ET948_RS00095	COG0142	geranyltranstransferase activity
ET948_RS00100	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ET948_RS00105	COG0564	pseudouridine synthase activity
ET948_RS00110	COG3098	single-species biofilm formation
ET948_RS00140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ET948_RS00145	COG0254	rRNA binding
ET948_RS00150	COG1720	tRNA m6t6A37 methyltransferase activity
ET948_RS00155	COG0442	prolyl-tRNA aminoacylation
ET948_RS00175	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ET948_RS00185	COG0583	DNA-binding transcription factor activity
ET948_RS00195	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ET948_RS00205	COG3327	negative regulation of DNA-templated transcription, initiation
ET948_RS00210	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ET948_RS00215	COG0183	Belongs to the thiolase family
ET948_RS00220	COG2050	protein possibly involved in aromatic compounds catabolism
ET948_RS00225	COG1250	3-hydroxyacyl-CoA dehydrogenase
ET948_RS00230	COG1024	Enoyl-CoA hydratase
ET948_RS00235	COG1024	Enoyl-CoA hydratase
ET948_RS00240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ET948_RS00245	COG2151	metal-sulfur cluster biosynthetic enzyme
ET948_RS00250	COG3396	Phenylacetate-CoA oxygenase
ET948_RS00255	COG3460	Phenylacetate-CoA oxygenase
ET948_RS00260	COG3396	Phenylacetate-CoA oxygenase
ET948_RS00265	COG1012	belongs to the aldehyde dehydrogenase family
ET948_RS00265	COG2030	dehydratase
ET948_RS00285	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ET948_RS00315	COG0484	heat shock protein binding
ET948_RS00320	COG0443	Heat shock 70 kDa protein
ET948_RS00325	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ET948_RS00330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ET948_RS00335	COG0497	DNA recombination
ET948_RS00340	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ET948_RS00345	COG2914	Belongs to the UPF0125 (RnfH) family
ET948_RS00350	COG2867	negative regulation of translational initiation
ET948_RS00355	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ET948_RS00380	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ET948_RS00395	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ET948_RS00415	COG2273	Hydrolase Family 16
ET948_RS00415	COG5297	Belongs to the glycosyl hydrolase family 6
ET948_RS00420	COG1609	Transcriptional regulator
ET948_RS00430	COG2017	converts alpha-aldose to the beta-anomer
ET948_RS00435	COG3459	Glycosyltransferase 36 associated
ET948_RS00440	COG3842	ATPase activity
ET948_RS00445	COG2723	6-phospho-beta-galactosidase activity
ET948_RS00450	COG0395	ABC-type sugar transport system, permease component
ET948_RS00465	COG1609	Transcriptional regulator
ET948_RS00475	COG2190	(PTS) system
ET948_RS00475	COG1263	PTS System
ET948_RS00475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET948_RS00480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET948_RS00480	COG2190	(PTS) system
ET948_RS00480	COG1263	PTS System
ET948_RS00485	COG2723	6-phospho-beta-galactosidase activity
ET948_RS00490	COG1609	Transcriptional regulator
ET948_RS00495	COG1929	Belongs to the glycerate kinase type-1 family
ET948_RS00500	COG3381	protein complex oligomerization
ET948_RS00505	COG3302	dmso reductase anchor subunit
ET948_RS00510	COG0437	4 iron, 4 sulfur cluster binding
ET948_RS00515	COG0243	molybdopterin cofactor binding
ET948_RS00520	COG1464	Belongs to the NlpA lipoprotein family
ET948_RS00540	COG4628	conserved protein (DUF2132)
ET948_RS00545	COG2239	Acts as a magnesium transporter
ET948_RS00560	COG1115	amino acid carrier protein
ET948_RS00565	COG1584	GPR1 FUN34 yaaH family protein
ET948_RS00580	COG5002	protein histidine kinase activity
ET948_RS00590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ET948_RS00595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ET948_RS00605	COG0454	-acetyltransferase
ET948_RS00690	COG0582	viral genome integration into host DNA
ET948_RS00700	COG0517	IMP dehydrogenase activity
ET948_RS00700	COG0516	GMP reductase activity
ET948_RS00705	COG1570	exodeoxyribonuclease VII activity
ET948_RS00715	COG1160	GTP binding
ET948_RS00720	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ET948_RS00725	COG2976	Protein conserved in bacteria
ET948_RS00730	COG0124	histidyl-tRNA synthetase
ET948_RS00735	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ET948_RS00740	COG1426	Protein conserved in bacteria
ET948_RS00745	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ET948_RS00755	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ET948_RS00760	COG2975	iron-sulfur cluster assembly
ET948_RS00765	COG0633	Ferredoxin
ET948_RS00775	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ET948_RS00785	COG0822	iron-sulfur transferase activity
ET948_RS00790	COG1104	cysteine desulfurase activity
ET948_RS00795	COG1959	2 iron, 2 sulfur cluster binding
ET948_RS00805	COG0483	inositol monophosphate 1-phosphatase activity
ET948_RS00810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ET948_RS00815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ET948_RS00820	COG1862	Preprotein translocase
ET948_RS00835	COG0517	IMP dehydrogenase activity
ET948_RS00845	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ET948_RS00850	COG0583	DNA-binding transcription factor activity
ET948_RS00855	COG0450	alkyl hydroperoxide reductase
ET948_RS00865	COG0704	Plays a role in the regulation of phosphate uptake
ET948_RS00870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ET948_RS00875	COG0581	inorganic phosphate transmembrane transporter activity
ET948_RS00880	COG0573	inorganic phosphate transmembrane transporter activity
ET948_RS00885	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ET948_RS00890	COG0248	Ppx GppA phosphatase
ET948_RS00900	COG5002	protein histidine kinase activity
ET948_RS00905	COG0745	RESPONSE REGULATOR receiver
ET948_RS00915	COG0826	peptidase U32
ET948_RS00920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ET948_RS00940	COG3248	Nucleoside-binding outer membrane protein
ET948_RS00945	COG0737	Belongs to the 5'-nucleotidase family
ET948_RS00950	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ET948_RS00955	COG0693	protein deglycase activity
ET948_RS00960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ET948_RS00965	COG2166	iron-sulfur cluster assembly
ET948_RS00970	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ET948_RS00975	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ET948_RS00985	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ET948_RS00985	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ET948_RS00995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ET948_RS01000	COG1074	ATP-dependent DNA helicase activity
ET948_RS01005	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ET948_RS01015	COG0583	DNA-binding transcription factor activity
ET948_RS01020	COG3141	response to X-ray
ET948_RS01025	COG2171	N-acyltransferase activity
ET948_RS01030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ET948_RS01045	COG0189	ligase activity
ET948_RS01045	COG0569	domain protein
ET948_RS01055	COG2059	Chromate
ET948_RS01065	COG1022	Amp-dependent synthetase and ligase
ET948_RS01070	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ET948_RS01075	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ET948_RS01085	COG0560	Phosphoserine phosphatase
ET948_RS01095	COG0813	purine-nucleoside phosphorylase activity
ET948_RS01100	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ET948_RS01105	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ET948_RS01115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ET948_RS01120	COG0084	hydrolase, TatD family'
ET948_RS01130	COG3022	response to hydroperoxide
ET948_RS01135	COG1115	amino acid carrier protein
ET948_RS01150	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ET948_RS01160	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
ET948_RS01165	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ET948_RS01170	COG0083	homoserine kinase activity
ET948_RS01190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ET948_RS01205	COG0745	RESPONSE REGULATOR receiver
ET948_RS01215	COG0784	Response regulator, receiver
ET948_RS01215	COG2198	Histidine kinase
ET948_RS01215	COG5002	protein histidine kinase activity
ET948_RS01220	COG1242	4 iron, 4 sulfur cluster binding
ET948_RS01225	COG0070	glutamate synthase
ET948_RS01225	COG0069	glutamate synthase activity
ET948_RS01225	COG0067	glutamate synthase
ET948_RS01235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ET948_RS01245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET948_RS01250	COG2860	membrane
ET948_RS01295	COG0730	response to heat
ET948_RS01300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ET948_RS01305	COG0505	Belongs to the CarA family
ET948_RS01315	COG0494	nUDIX hydrolase
ET948_RS01320	COG0653	protein targeting
ET948_RS01325	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ET948_RS01330	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ET948_RS01335	COG0849	cell division
ET948_RS01340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ET948_RS01345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ET948_RS01350	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ET948_RS01355	COG0772	Belongs to the SEDS family
ET948_RS01360	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ET948_RS01370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ET948_RS01375	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ET948_RS01380	COG0768	penicillin binding
ET948_RS01385	COG3116	cell division
ET948_RS01400	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ET948_RS01405	COG3107	peptidoglycan biosynthetic process
ET948_RS01410	COG0792	nuclease activity
ET948_RS01415	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ET948_RS01420	COG2823	Periplasmic or secreted lipoprotein
ET948_RS01425	COG2969	positive regulation of protein catabolic process
ET948_RS01430	COG0625	glutathione transferase activity
ET948_RS01435	COG2857	Cytochrome c1
ET948_RS01440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ET948_RS01445	COG0723	plastoquinol--plastocyanin reductase activity
ET948_RS01450	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ET948_RS01455	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ET948_RS01470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ET948_RS01475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ET948_RS01480	COG0335	large ribosomal subunit rRNA binding
ET948_RS01485	COG0336	Belongs to the RNA methyltransferase TrmD family
ET948_RS01490	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ET948_RS01495	COG0228	four-way junction DNA binding
ET948_RS01500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ET948_RS01505	COG4137	Cytochrome C assembly protein
ET948_RS01510	COG4536	flavin adenine dinucleotide binding
ET948_RS01515	COG1854	S-ribosylhomocysteine lyase activity
ET948_RS01520	COG2918	glutathione biosynthetic process
ET948_RS01525	COG0612	Peptidase, M16
ET948_RS01530	COG1238	metal cluster binding
ET948_RS01540	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ET948_RS01545	COG5016	pyruvate
ET948_RS01545	COG0511	ligase activity, forming carbon-carbon bonds
ET948_RS01550	COG3630	sodium ion export across plasma membrane
ET948_RS01595	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ET948_RS01600	COG0527	aspartate kinase activity
ET948_RS01605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ET948_RS01615	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ET948_RS01620	COG1546	Belongs to the CinA family
ET948_RS01625	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ET948_RS01630	COG4208	sulfate ABC transporter
ET948_RS01650	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ET948_RS01655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ET948_RS01660	COG1388	LysM domain
ET948_RS01660	COG4942	peptidase
ET948_RS01665	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ET948_RS01670	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ET948_RS01675	COG0585	pseudouridine synthase activity
ET948_RS01685	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ET948_RS01690	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ET948_RS01695	COG1968	undecaprenyl-diphosphatase activity
ET948_RS01700	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ET948_RS01705	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ET948_RS01710	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ET948_RS01715	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ET948_RS01720	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ET948_RS01725	COG1610	YqeY-like protein
ET948_RS01730	COG0358	DNA primase activity
ET948_RS01750	COG3550	peptidyl-serine autophosphorylation
ET948_RS01810	COG0732	type I restriction modification DNA specificity domain
ET948_RS01865	COG1136	(ABC) transporter
ET948_RS01880	COG1309	transcriptional regulator
ET948_RS01900	COG2433	Pfam Transposase IS66
ET948_RS01950	COG2003	Belongs to the UPF0758 family
ET948_RS01990	COG0328	RNA-DNA hybrid ribonuclease activity
ET948_RS02025	COG3550	peptidyl-serine autophosphorylation
ET948_RS02030	COG1280	lysine exporter protein (LysE YggA)
ET948_RS02035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ET948_RS02040	COG1279	arginine transmembrane transporter activity
ET948_RS02070	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ET948_RS02080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ET948_RS02095	COG3381	protein complex oligomerization
ET948_RS02100	COG3302	dmso reductase anchor subunit
ET948_RS02105	COG0437	4 iron, 4 sulfur cluster binding
ET948_RS02110	COG0243	molybdopterin cofactor binding
ET948_RS02120	COG1902	pentaerythritol trinitrate reductase activity
ET948_RS02125	COG0583	DNA-binding transcription factor activity
ET948_RS02130	COG2731	YhcH YjgK YiaL family protein
ET948_RS02145	COG2115	Belongs to the xylose isomerase family
ET948_RS02150	COG2814	Major facilitator Superfamily
ET948_RS02150	COG0477	Major facilitator Superfamily
ET948_RS02155	COG2207	Transcriptional regulator
ET948_RS02155	COG1609	Transcriptional regulator
ET948_RS02160	COG1070	Carbohydrate kinase
ET948_RS02165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ET948_RS02180	COG1349	DNA-binding transcription factor activity
ET948_RS02195	COG1349	DNA-binding transcription factor activity
ET948_RS02205	COG5002	protein histidine kinase activity
ET948_RS02205	COG5001	Diguanylate cyclase
ET948_RS02205	COG3447	MASE1 domain protein
ET948_RS02215	COG0668	transmembrane transport
ET948_RS02220	COG0191	fructose-bisphosphate aldolase activity
ET948_RS02225	COG0126	phosphoglycerate kinase activity
ET948_RS02230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ET948_RS02235	COG4771	TonB-dependent receptor
ET948_RS02240	COG0583	DNA-binding transcription factor activity
ET948_RS02245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ET948_RS02250	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ET948_RS02260	COG2356	endonuclease I
ET948_RS02265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ET948_RS02270	COG0189	ligase activity
ET948_RS02275	COG1678	Uncharacterized ACR, COG1678
ET948_RS02280	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ET948_RS02295	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ET948_RS02300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ET948_RS02305	COG0762	integral membrane protein
ET948_RS02310	COG1872	DUF167
ET948_RS02320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ET948_RS02325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ET948_RS02330	COG2066	Belongs to the glutaminase family
ET948_RS02335	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ET948_RS02340	COG1194	a g-specific adenine glycosylase
ET948_RS02345	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ET948_RS02350	COG0741	lytic transglycosylase activity
ET948_RS02375	COG0840	transmembrane signaling receptor activity
ET948_RS02405	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ET948_RS02410	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ET948_RS02415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ET948_RS02420	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ET948_RS02425	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ET948_RS02430	COG2967	ApaG domain
ET948_RS02445	COG3610	response to peptide
ET948_RS02450	COG2966	Psort location CytoplasmicMembrane, score
ET948_RS02455	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ET948_RS02465	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ET948_RS02470	COG0142	geranyltranstransferase activity
ET948_RS02475	COG0039	L-malate dehydrogenase activity
ET948_RS02480	COG1438	arginine binding
ET948_RS02485	COG2358	TRAP transporter, solute receptor (TAXI family
ET948_RS02495	COG0589	response to stress
ET948_RS02515	COG0312	modulator of DNA gyrase
ET948_RS02520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ET948_RS02525	COG3164	Protein of unknown function
ET948_RS02530	COG1530	ribonuclease E activity
ET948_RS02535	COG0424	maF-like protein
ET948_RS02540	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ET948_RS02545	COG1792	Involved in formation and maintenance of cell shape
ET948_RS02550	COG1077	Cell shape determining protein MreB Mrl
ET948_RS02580	COG2165	general secretion pathway protein
ET948_RS02595	COG1459	type II secretion system
ET948_RS02600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ET948_RS02610	COG3267	Type II secretory pathway component ExeA
ET948_RS02610	COG3409	Peptidoglycan-binding domain 1 protein
ET948_RS02635	COG2199	diguanylate cyclase activity
ET948_RS02635	COG2200	EAL domain
ET948_RS02645	COG2197	response regulator
ET948_RS02655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ET948_RS02665	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ET948_RS02670	COG0527	aspartate kinase activity
ET948_RS02675	COG0646	methionine synthase
ET948_RS02675	COG1410	methionine synthase
ET948_RS02715	COG0175	sulfate reduction
ET948_RS02720	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ET948_RS02740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ET948_RS02745	COG0735	belongs to the Fur family
ET948_RS02760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ET948_RS02785	COG0360	Binds together with S18 to 16S ribosomal RNA
ET948_RS02795	COG2906	2 iron, 2 sulfur cluster binding
ET948_RS02805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ET948_RS02810	COG0049	tRNA binding
ET948_RS02820	COG2168	tRNA wobble position uridine thiolation
ET948_RS02825	COG2923	Belongs to the DsrF TusC family
ET948_RS02830	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ET948_RS02835	COG2964	Protein conserved in bacteria
ET948_RS02840	COG0545	Peptidyl-prolyl cis-trans isomerase
ET948_RS02850	COG2900	Belongs to the SlyX family
ET948_RS02860	COG0330	HflC and HflK could
ET948_RS02865	COG0330	HflC and HflK could
ET948_RS02870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ET948_RS02875	COG1923	regulation of RNA biosynthetic process
ET948_RS02880	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ET948_RS02885	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ET948_RS02895	COG0802	atpase or kinase
ET948_RS02900	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ET948_RS02950	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ET948_RS02955	COG1162	GTPase activity
ET948_RS02960	COG0688	phosphatidylethanolamine metabolic process
ET948_RS02965	COG0471	metal ion transport
ET948_RS02970	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ET948_RS02975	COG4942	peptidase
ET948_RS02990	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ET948_RS02995	COG2816	NAD+ diphosphatase activity
ET948_RS03000	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ET948_RS03005	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ET948_RS03010	COG0085	RNA polymerase activity
ET948_RS03015	COG0222	ribosome binding
ET948_RS03020	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ET948_RS03035	COG0250	Participates in transcription elongation, termination and antitermination
ET948_RS03040	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ET948_RS03070	COG1072	(Pantothenic acid kinase))
ET948_RS03080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ET948_RS03090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ET948_RS03155	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ET948_RS03165	COG3118	belongs to the thioredoxin family
ET948_RS03175	COG0248	Ppx GppA phosphatase
ET948_RS03180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET948_RS03180	COG2198	Histidine kinase
ET948_RS03180	COG2205	protein histidine kinase activity
ET948_RS03180	COG0784	Response regulator, receiver
ET948_RS03185	COG2814	Major facilitator Superfamily
ET948_RS03200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ET948_RS03205	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ET948_RS03210	COG0511	ligase activity, forming carbon-carbon bonds
ET948_RS03215	COG0439	Biotin carboxylase
ET948_RS03220	COG2264	protein methyltransferase activity
ET948_RS03225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ET948_RS03230	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ET948_RS03235	COG0840	transmembrane signaling receptor activity
ET948_RS03240	COG1982	Orn Lys Arg decarboxylase major
ET948_RS03245	COG0531	amino acid
ET948_RS03250	COG3710	Transcriptional regulator
ET948_RS03260	COG0138	bifunctional purine biosynthesis protein purh
ET948_RS03275	COG0776	regulation of translation
ET948_RS03280	COG1253	flavin adenine dinucleotide binding
ET948_RS03285	COG0668	transmembrane transport
ET948_RS03290	COG3068	Protein conserved in bacteria
ET948_RS03295	COG1573	uracil-dna glycosylase
ET948_RS03300	COG0737	Belongs to the 5'-nucleotidase family
ET948_RS03320	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ET948_RS03330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ET948_RS03355	COG0662	Cupin 2, conserved barrel domain protein
ET948_RS03355	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ET948_RS03360	COG1051	belongs to the nudix hydrolase family
ET948_RS03365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ET948_RS03370	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ET948_RS03435	COG5433	transposase activity
ET948_RS03475	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ET948_RS03485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ET948_RS03495	COG1560	Kdo2-lipid A biosynthetic process
ET948_RS03510	COG0438	transferase activity, transferring glycosyl groups
ET948_RS03525	COG0859	PFAM glycosyl transferase family 9
ET948_RS03530	COG1519	Transferase
ET948_RS03540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ET948_RS03545	COG0859	PFAM glycosyl transferase family 9
ET948_RS03550	COG0463	Glycosyl transferase, family 2
ET948_RS03555	COG0438	transferase activity, transferring glycosyl groups
ET948_RS03560	COG0438	transferase activity, transferring glycosyl groups
ET948_RS03565	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ET948_RS03575	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ET948_RS03585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ET948_RS03590	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ET948_RS03595	COG2003	Belongs to the UPF0758 family
ET948_RS03605	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ET948_RS03610	COG1309	transcriptional regulator
ET948_RS03615	COG1560	Kdo2-lipid A biosynthetic process
ET948_RS03620	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ET948_RS03625	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ET948_RS03630	COG1561	YicC-like family, N-terminal region
ET948_RS03660	COG2301	Belongs to the HpcH HpaI aldolase family
ET948_RS03665	COG3052	prosthetic group binding
ET948_RS03670	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ET948_RS03680	COG3630	sodium ion export across plasma membrane
ET948_RS03685	COG0511	ligase activity, forming carbon-carbon bonds
ET948_RS03685	COG5016	pyruvate
ET948_RS03690	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ET948_RS03700	COG4565	transcriptional regulatory protein
ET948_RS03715	COG1228	amidohydrolase
ET948_RS03720	COG2862	Uncharacterized protein family, UPF0114
ET948_RS03725	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ET948_RS03735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET948_RS03740	COG1120	ATPase activity
ET948_RS03750	COG1132	(ABC) transporter
ET948_RS03760	COG0514	ATP-dependent DNA helicase (RecQ)
ET948_RS03765	COG2962	Rard protein
ET948_RS03780	COG0210	DNA helicase
ET948_RS03785	COG0339	signal peptide processing
ET948_RS03790	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ET948_RS03795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ET948_RS03820	COG1196	nuclear chromosome segregation
ET948_RS03825	COG1074	ATP-dependent DNA helicase activity
ET948_RS03845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET948_RS03850	COG0601	transmembrane transport
ET948_RS03855	COG0747	negative chemotaxis
ET948_RS03860	COG4172	Belongs to the ABC transporter superfamily
ET948_RS03900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ET948_RS03910	COG2960	long-chain fatty acid transporting porin activity
ET948_RS03915	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ET948_RS03920	COG0583	DNA-binding transcription factor activity
ET948_RS03925	COG3335	DDE superfamily endonuclease
ET948_RS03965	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ET948_RS03980	COG0408	coproporphyrinogen oxidase activity
ET948_RS03985	COG0009	L-threonylcarbamoyladenylate synthase
ET948_RS03990	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ET948_RS03995	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ET948_RS04000	COG0551	DNA topoisomerase type I activity
ET948_RS04010	COG0758	DNA mediated transformation
ET948_RS04020	COG0242	peptide deformylase activity
ET948_RS04030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ET948_RS04030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ET948_RS04035	COG0569	domain protein
ET948_RS04040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ET948_RS04050	COG1272	protein, Hemolysin III
ET948_RS04055	COG4326	sporulation control protein
ET948_RS04065	COG3084	Protein conserved in bacteria
ET948_RS04075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ET948_RS04080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ET948_RS04085	COG0606	chelatase, subunit chli
ET948_RS04095	COG3978	acetolactate synthase activity
ET948_RS04100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ET948_RS04105	COG0129	dihydroxy-acid dehydratase activity
ET948_RS04115	COG0604	alcohol dehydrogenase
ET948_RS04120	COG0425	Belongs to the sulfur carrier protein TusA family
ET948_RS04130	COG2119	membrane
ET948_RS04135	COG0752	glycyl-tRNA synthetase alpha subunit
ET948_RS04140	COG0751	glycine-tRNA ligase activity
ET948_RS04220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ET948_RS04225	COG1739	Uncharacterized protein family UPF0029
ET948_RS04230	COG1250	3-hydroxyacyl-CoA dehydrogenase
ET948_RS04230	COG1024	Enoyl-CoA hydratase
ET948_RS04235	COG0183	Belongs to the thiolase family
ET948_RS04240	COG0583	DNA-binding transcription factor activity
ET948_RS04245	COG2814	Major facilitator Superfamily
ET948_RS04255	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ET948_RS04260	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ET948_RS04265	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ET948_RS04270	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ET948_RS04290	COG0356	it plays a direct role in the translocation of protons across the membrane
ET948_RS04300	COG1475	DNA binding
ET948_RS04305	COG1192	Involved in chromosome partitioning
ET948_RS04310	COG0357	Ribosomal RNA small subunit methyltransferase G
ET948_RS04315	COG0445	tRNA wobble uridine modification
ET948_RS04320	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ET948_RS04325	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ET948_RS04330	COG0706	membrane insertase activity
ET948_RS04340	COG0594	ribonuclease P activity
ET948_RS04345	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ET948_RS04350	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ET948_RS04355	COG0592	DNA-directed DNA polymerase activity
ET948_RS04365	COG0187	DNA topoisomerase II activity
ET948_RS04380	COG0071	Belongs to the small heat shock protein (HSP20) family
ET948_RS04385	COG3977	Valine--pyruvate aminotransferase
ET948_RS04390	COG0366	Alpha amylase catalytic
ET948_RS04405	COG0038	chloride channel
ET948_RS04410	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ET948_RS04420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ET948_RS04425	COG2104	thiamine diphosphate biosynthetic process
ET948_RS04430	COG2022	thiamine diphosphate biosynthetic process
ET948_RS04435	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ET948_RS04440	COG0006	proline dipeptidase activity
ET948_RS04440	COG0006	proline dipeptidase activity
ET948_RS04460	COG1522	sequence-specific DNA binding
ET948_RS04480	COG0589	response to stress
ET948_RS04485	COG1528	Iron-storage protein
ET948_RS04495	COG2081	HI0933 family
ET948_RS04500	COG0840	transmembrane signaling receptor activity
ET948_RS04505	COG1172	Belongs to the binding-protein-dependent transport system permease family
ET948_RS04510	COG1129	ABC transporter
ET948_RS04515	COG1879	ABC-type sugar transport system periplasmic component
ET948_RS04520	COG1069	ribulokinase activity
ET948_RS04525	COG0235	Class ii aldolase
ET948_RS04530	COG2160	L-arabinose isomerase activity
ET948_RS04545	COG1322	Protein conserved in bacteria
ET948_RS04550	COG2226	methyltransferase
ET948_RS04555	COG3165	ubiquinone biosynthetic process from chorismate
ET948_RS04565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ET948_RS04570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ET948_RS04575	COG0805	protein transport
ET948_RS04580	COG0084	hydrolase, TatD family'
ET948_RS04590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ET948_RS04590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ET948_RS04625	COG3071	HemY protein
ET948_RS04630	COG2959	enzyme of heme biosynthesis
ET948_RS04635	COG1587	Uroporphyrinogen-III synthase
ET948_RS04640	COG0181	hydroxymethylbilane synthase activity
ET948_RS04650	COG1965	Belongs to the frataxin family
ET948_RS04660	COG0019	diaminopimelate decarboxylase activity
ET948_RS04665	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ET948_RS04675	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ET948_RS04680	COG1011	Hydrolase
ET948_RS04685	COG3287	FIST C domain
ET948_RS04685	COG2200	EAL domain
ET948_RS04685	COG2199	diguanylate cyclase activity
ET948_RS04690	COG3148	PFAM DTW domain containing protein
ET948_RS04700	COG0561	phosphatase activity
ET948_RS04710	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ET948_RS04715	COG0783	Belongs to the Dps family
ET948_RS04745	COG0742	ribosomal rna small subunit methyltransferase
ET948_RS04750	COG0552	protein localization to endoplasmic reticulum
ET948_RS04755	COG2884	Cell division ATP-binding protein ftsE
ET948_RS04760	COG2177	Part of the ABC transporter FtsEX involved in
ET948_RS04765	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ET948_RS04780	COG1580	Controls the rotational direction of flagella during chemotaxis
ET948_RS04785	COG3161	chorismate lyase activity
ET948_RS04790	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ET948_RS04795	COG2937	Belongs to the GPAT DAPAT family
ET948_RS04800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ET948_RS04810	COG0534	Mate efflux family protein
ET948_RS04815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ET948_RS04840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ET948_RS04910	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ET948_RS04915	COG2204	response regulator
ET948_RS04920	COG3852	Histidine kinase
ET948_RS04930	COG0174	glutamine synthetase
ET948_RS04935	COG1217	gtp-binding protein TYPA
ET948_RS04945	COG1490	D-aminoacyl-tRNA deacylase activity
ET948_RS04950	COG0456	acetyltransferase
ET948_RS04960	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ET948_RS04965	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ET948_RS04970	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ET948_RS04975	COG3031	protein transport across the cell outer membrane
ET948_RS04985	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ET948_RS04990	COG1459	type II secretion system
ET948_RS04995	COG2165	general secretion pathway protein
ET948_RS05000	COG2165	general secretion pathway protein
ET948_RS05005	COG2165	general secretion pathway protein
ET948_RS05010	COG4795	General secretion pathway protein
ET948_RS05015	COG3156	type II secretion system protein K
ET948_RS05020	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ET948_RS05025	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ET948_RS05035	COG1218	3'(2'),5'-bisphosphate nucleotidase
ET948_RS05040	COG0494	nUDIX hydrolase
ET948_RS05050	COG1040	competence protein
ET948_RS05055	COG0596	Alpha beta hydrolase
ET948_RS05065	COG2183	response to ionizing radiation
ET948_RS05075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ET948_RS05080	COG1609	Transcriptional regulator
ET948_RS05085	COG0129	dihydroxy-acid dehydratase activity
ET948_RS05090	COG3265	gluconokinase activity
ET948_RS05095	COG2610	gluconate transmembrane transporter activity
ET948_RS05100	COG0800	Aldolase
ET948_RS05115	COG2233	PERMEase
ET948_RS05120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ET948_RS05125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ET948_RS05130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ET948_RS05135	COG1758	RNA polymerase activity
ET948_RS05140	COG0194	GDP metabolic process
ET948_RS05145	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ET948_RS05150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ET948_RS05185	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ET948_RS05190	COG1027	Aspartate ammonia-lyase
ET948_RS05195	COG3030	protein affecting phage T7 exclusion by the F plasmid
ET948_RS05200	COG1278	Cold shock
ET948_RS05205	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ET948_RS05210	COG2205	protein histidine kinase activity
ET948_RS05215	COG0745	RESPONSE REGULATOR receiver
ET948_RS05225	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ET948_RS05230	COG0205	6-phosphofructokinase activity
ET948_RS05235	COG1494	fructose-1,6-bisphosphatase
ET948_RS05240	COG3074	FtsZ-dependent cytokinesis
ET948_RS05245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ET948_RS05250	COG0460	homoserine dehydrogenase
ET948_RS05250	COG0527	aspartate kinase activity
ET948_RS05255	COG0626	cystathionine gamma-synthase activity
ET948_RS05265	COG0281	malic enzyme
ET948_RS05275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ET948_RS05280	COG1609	Transcriptional regulator
ET948_RS05290	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ET948_RS05295	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ET948_RS05300	COG1575	Belongs to the MenA family. Type 1 subfamily
ET948_RS05305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ET948_RS05310	COG0534	Mate efflux family protein
ET948_RS05315	COG0149	triose-phosphate isomerase activity
ET948_RS05345	COG0459	protein refolding
ET948_RS05365	COG1119	ATPase activity
ET948_RS05370	COG1285	pathogenesis
ET948_RS05375	COG1509	lysine 2,3-aminomutase activity
ET948_RS05390	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ET948_RS05395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ET948_RS05400	COG1053	succinate dehydrogenase
ET948_RS05405	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ET948_RS05410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ET948_RS05415	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ET948_RS05420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ET948_RS05425	COG1045	serine acetyltransferase
ET948_RS05435	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ET948_RS05440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ET948_RS05445	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ET948_RS05450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ET948_RS05455	COG0137	argininosuccinate synthase activity
ET948_RS05460	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ET948_RS05460	COG0165	Argininosuccinate lyase
ET948_RS05470	COG0678	peroxiredoxin activity
ET948_RS05470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ET948_RS05480	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ET948_RS05515	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ET948_RS05525	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ET948_RS05530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ET948_RS05535	COG0546	phosphoglycolate phosphatase activity
ET948_RS05540	COG0180	Tryptophanyl-tRNA synthetase
ET948_RS05550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ET948_RS05575	COG3954	Phosphoribulokinase
ET948_RS05585	COG0429	hydrolase of the alpha beta-hydrolase fold
ET948_RS05595	COG0488	(ABC) transporter
ET948_RS05615	COG1047	Peptidyl-prolyl cis-trans
ET948_RS05620	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ET948_RS05625	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ET948_RS05630	COG0557	exoribonuclease II activity
ET948_RS05635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ET948_RS05640	COG0051	transcription antitermination factor activity, RNA binding
ET948_RS05645	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ET948_RS05650	COG0088	Forms part of the polypeptide exit tunnel
ET948_RS05655	COG0089	rRNA binding
ET948_RS05660	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ET948_RS05665	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ET948_RS05670	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ET948_RS05675	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ET948_RS05680	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ET948_RS05685	COG0255	Belongs to the universal ribosomal protein uL29 family
ET948_RS05690	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ET948_RS05695	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ET948_RS05700	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ET948_RS05705	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ET948_RS05710	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ET948_RS05715	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ET948_RS05730	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ET948_RS05735	COG1841	ribosomal large subunit assembly
ET948_RS05740	COG0200	Binds to the 23S rRNA
ET948_RS05745	COG0201	protein transport
ET948_RS05750	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ET948_RS05755	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ET948_RS05760	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ET948_RS05765	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ET948_RS05770	COG0202	RNA polymerase activity
ET948_RS05775	COG0203	ribosomal protein L17
ET948_RS05780	COG0545	Peptidyl-prolyl cis-trans isomerase
ET948_RS05790	COG2153	protein acetylation
ET948_RS05795	COG0513	Belongs to the DEAD box helicase family
ET948_RS05800	COG0737	Belongs to the 5'-nucleotidase family
ET948_RS05805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ET948_RS05805	COG1648	precorrin-2 dehydrogenase activity
ET948_RS05810	COG0175	sulfate reduction
ET948_RS05815	COG2895	sulfate adenylyltransferase (ATP) activity
ET948_RS05820	COG0529	Catalyzes the synthesis of activated sulfate
ET948_RS05840	COG1136	(ABC) transporter
ET948_RS05855	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ET948_RS05860	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ET948_RS05865	COG0729	surface antigen
ET948_RS05875	COG2105	PFAM AIG2 family protein
ET948_RS05880	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ET948_RS05885	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ET948_RS05890	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ET948_RS05895	COG0163	prenyltransferase activity
ET948_RS05905	COG1178	ABC-type Fe3 transport system permease component
ET948_RS05910	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ET948_RS05915	COG3028	Belongs to the UPF0307 family
ET948_RS05920	COG0312	modulator of DNA gyrase
ET948_RS05925	COG2239	Acts as a magnesium transporter
ET948_RS05930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET948_RS05935	COG1660	Displays ATPase and GTPase activities
ET948_RS05940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET948_RS05945	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ET948_RS05955	COG1137	ATPase activity
ET948_RS05960	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ET948_RS05965	COG3117	lipopolysaccharide transmembrane transporter activity
ET948_RS05970	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ET948_RS05985	COG1127	ABC transporter
ET948_RS05990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ET948_RS05995	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ET948_RS06000	COG2854	intermembrane phospholipid transfer
ET948_RS06010	COG5007	Belongs to the BolA IbaG family
ET948_RS06015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ET948_RS06020	COG0204	Acyl-transferase
ET948_RS06025	COG0251	oxidation-reduction process
ET948_RS06040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ET948_RS06045	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ET948_RS06050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ET948_RS06060	COG0564	pseudouridine synthase activity
ET948_RS06065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ET948_RS06070	COG0525	valine-tRNA ligase activity
ET948_RS06075	COG2927	DNA polymerase III (CHI subunit)
ET948_RS06080	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ET948_RS06085	COG0795	lipopolysaccharide-transporting ATPase activity
ET948_RS06090	COG0795	lipopolysaccharide-transporting ATPase activity
ET948_RS06105	COG5001	Diguanylate cyclase
ET948_RS06110	COG3437	response regulator, receiver
ET948_RS06145	COG5433	transposase activity
ET948_RS06150	COG0066	3-isopropylmalate dehydratase activity
ET948_RS06155	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ET948_RS06160	COG0473	3-isopropylmalate dehydrogenase activity
ET948_RS06180	COG0583	DNA-binding transcription factor activity
ET948_RS06185	COG1022	Amp-dependent synthetase and ligase
ET948_RS06190	COG0028	Belongs to the TPP enzyme family
ET948_RS06200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ET948_RS06205	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ET948_RS06210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ET948_RS06220	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ET948_RS06225	COG3079	Belongs to the UPF0149 family
ET948_RS06230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ET948_RS06235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ET948_RS06255	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ET948_RS06265	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ET948_RS06270	COG1595	DNA-templated transcription, initiation
ET948_RS06280	COG3026	antisigma factor binding
ET948_RS06285	COG3086	response to oxidative stress
ET948_RS06290	COG0481	GTPase activity
ET948_RS06300	COG0571	ribonuclease III activity
ET948_RS06305	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ET948_RS06310	COG1381	Involved in DNA repair and RecF pathway recombination
ET948_RS06315	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ET948_RS06330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ET948_RS06335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ET948_RS06340	COG3956	TIGRFAM MazG family protein
ET948_RS06345	COG0504	CTP synthase activity
ET948_RS06350	COG0148	phosphopyruvate hydratase activity
ET948_RS06355	COG0617	tRNA 3'-terminal CCA addition
ET948_RS06360	COG4991	sh3 domain protein
ET948_RS06365	COG0306	phosphate transporter
ET948_RS06370	COG1392	Phosphate transport regulator
ET948_RS06375	COG3025	triphosphatase activity
ET948_RS06385	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ET948_RS06390	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ET948_RS06390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ET948_RS06395	COG1538	Outer membrane efflux protein
ET948_RS06400	COG0494	nUDIX hydrolase
ET948_RS06405	COG3151	Protein conserved in bacteria
ET948_RS06415	COG3150	esterase
ET948_RS06420	COG0187	DNA topoisomerase II activity
ET948_RS06435	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ET948_RS06440	COG0237	dephospho-CoA kinase activity
ET948_RS06450	COG1459	type II secretion system
ET948_RS06455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ET948_RS06465	COG0157	Belongs to the NadC ModD family
ET948_RS06475	COG0716	FMN binding
ET948_RS06480	COG4974	Belongs to the 'phage' integrase family
ET948_RS06485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ET948_RS06490	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ET948_RS06495	COG2186	Transcriptional regulator
ET948_RS06500	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ET948_RS06505	COG0508	dehydrogenase complex catalyzes the overall conversion of
ET948_RS06510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ET948_RS06525	COG0288	reversible hydration of carbon dioxide
ET948_RS06530	COG1131	(ABC) transporter
ET948_RS06535	COG0842	Transport permease protein
ET948_RS06540	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ET948_RS06545	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ET948_RS06550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ET948_RS06560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ET948_RS06565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ET948_RS06575	COG0589	response to stress
ET948_RS06580	COG1643	Atp-dependent helicase
ET948_RS06585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ET948_RS06590	COG1752	Esterase of the alpha-beta hydrolase superfamily
ET948_RS06595	COG1049	propionate catabolic process, 2-methylcitrate cycle
ET948_RS06600	COG0745	RESPONSE REGULATOR receiver
ET948_RS06605	COG2205	protein histidine kinase activity
ET948_RS06610	COG4771	TonB-dependent receptor
ET948_RS06620	COG0347	Belongs to the P(II) protein family
ET948_RS06625	COG0004	ammonium transporteR
ET948_RS06630	COG3842	ATPase activity
ET948_RS06640	COG1840	ABC-type Fe3 transport system, periplasmic component
ET948_RS06645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ET948_RS06660	COG2971	BadF BadG BcrA BcrD
ET948_RS06670	COG4608	Belongs to the ABC transporter superfamily
ET948_RS06675	COG0444	Belongs to the ABC transporter superfamily
ET948_RS06690	COG0747	negative chemotaxis
ET948_RS06695	COG2205	protein histidine kinase activity
ET948_RS06695	COG0784	Response regulator, receiver
ET948_RS06705	COG0628	permease
ET948_RS06710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ET948_RS06715	COG0316	Belongs to the HesB IscA family
ET948_RS06720	COG0739	heme binding
ET948_RS06725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ET948_RS06730	COG2027	D-alanyl-D-alanine carboxypeptidase
ET948_RS06735	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ET948_RS06740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ET948_RS06745	COG1534	Rna-binding protein
ET948_RS06750	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ET948_RS06755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ET948_RS06760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ET948_RS06765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ET948_RS06770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ET948_RS06785	COG0779	Required for maturation of 30S ribosomal subunits
ET948_RS06790	COG0195	Participates in both transcription termination and antitermination
ET948_RS06800	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ET948_RS06810	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ET948_RS06815	COG1185	polyribonucleotide nucleotidyltransferase activity
ET948_RS06825	COG0826	peptidase U32
ET948_RS06830	COG0826	peptidase U32
ET948_RS06840	COG3154	lipid carrier protein
ET948_RS06845	COG3153	acetyltransferase
ET948_RS06865	COG0513	Belongs to the DEAD box helicase family
ET948_RS06870	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ET948_RS06890	COG2204	response regulator
ET948_RS06895	COG0667	Aldo Keto reductase
ET948_RS06900	COG3066	DNA modification
ET948_RS06905	COG0494	nUDIX hydrolase
ET948_RS06915	COG0730	response to heat
ET948_RS06920	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ET948_RS06925	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ET948_RS06930	COG1283	sodium-dependent phosphate transmembrane transporter activity
ET948_RS06935	COG0583	DNA-binding transcription factor activity
ET948_RS06940	COG0640	Transcriptional regulator
ET948_RS06945	COG0268	Binds directly to 16S ribosomal RNA
ET948_RS06950	COG0728	peptidoglycan biosynthetic process
ET948_RS06955	COG0196	riboflavin kinase activity
ET948_RS06960	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ET948_RS06965	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ET948_RS06970	COG1047	Peptidyl-prolyl cis-trans
ET948_RS06975	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ET948_RS06980	COG1966	Carbon starvation protein
ET948_RS06990	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ET948_RS07000	COG3279	Response regulator of the LytR AlgR family
ET948_RS07005	COG3275	phosphorelay sensor kinase activity
ET948_RS07010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ET948_RS07015	COG0287	Prephenate dehydrogenase
ET948_RS07015	COG1605	Chorismate mutase
ET948_RS07025	COG0488	(ABC) transporter
ET948_RS07030	COG0741	lytic transglycosylase activity
ET948_RS07035	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ET948_RS07045	COG1605	Chorismate mutase
ET948_RS07045	COG0077	Prephenate dehydratase
ET948_RS07050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ET948_RS07055	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ET948_RS07060	COG0564	pseudouridine synthase activity
ET948_RS07115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ET948_RS07130	COG0271	Belongs to the BolA IbaG family
ET948_RS07140	COG1805	sodium ion transport
ET948_RS07145	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ET948_RS07155	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ET948_RS07165	COG1477	protein flavinylation
ET948_RS07180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ET948_RS07190	COG0733	neurotransmitter:sodium symporter activity
ET948_RS07200	COG0189	ligase activity
ET948_RS07205	COG4067	protein conserved in archaea
ET948_RS07205	COG0189	ligase activity
ET948_RS07210	COG2195	Cleaves the N-terminal amino acid of tripeptides
ET948_RS07215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ET948_RS07220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ET948_RS07230	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ET948_RS07240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ET948_RS07245	COG2252	PERMEase
ET948_RS07250	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ET948_RS07255	COG1073	alpha beta
ET948_RS07265	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ET948_RS07270	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ET948_RS07275	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ET948_RS07280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ET948_RS07280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ET948_RS07295	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ET948_RS07300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ET948_RS07305	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ET948_RS07310	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ET948_RS07315	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ET948_RS07320	COG0024	Methionine aminopeptidase
ET948_RS07325	COG0052	Belongs to the universal ribosomal protein uS2 family
ET948_RS07330	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ET948_RS07340	COG0233	cytoplasmic translational termination
ET948_RS07345	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ET948_RS07355	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ET948_RS07360	COG0750	zinc metalloprotease
ET948_RS07370	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ET948_RS07375	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ET948_RS07380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ET948_RS07385	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ET948_RS07390	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ET948_RS07395	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ET948_RS07405	COG0825	malonyl-CoA metabolic process
ET948_RS07410	COG0037	tRNA processing
ET948_RS07420	COG0347	Belongs to the P(II) protein family
ET948_RS07425	COG3021	interspecies interaction between organisms
ET948_RS07435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ET948_RS07440	COG2226	methyltransferase
ET948_RS07445	COG0328	RNA-DNA hybrid ribonuclease activity
ET948_RS07460	COG1960	acyl-CoA dehydrogenase activity
ET948_RS07465	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ET948_RS07470	COG0121	glutamine amidotransferase
ET948_RS07475	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ET948_RS07480	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ET948_RS07485	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ET948_RS07490	COG1187	pseudouridine synthase activity
ET948_RS07495	COG2840	Smr protein MutS2
ET948_RS07515	COG2217	Heavy metal translocating P-type atpase
ET948_RS07515	COG2608	mercury ion transmembrane transporter activity
ET948_RS07520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ET948_RS07570	COG2747	anti-sigma28 factor FlgM
ET948_RS07580	COG0835	chemotaxis
ET948_RS07580	COG0784	Response regulator, receiver
ET948_RS07585	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ET948_RS07590	COG1815	bacterial-type flagellum-dependent cell motility
ET948_RS07605	COG1749	Flagellar hook protein flgE
ET948_RS07610	COG4787	bacterial-type flagellum-dependent cell motility
ET948_RS07620	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ET948_RS07625	COG1706	bacterial-type flagellum-dependent cell motility
ET948_RS07630	COG1705	Flagellar rod assembly protein muramidase FlgJ
ET948_RS07630	COG3951	Flagellar rod assembly protein muramidase FlgJ
ET948_RS07640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ET948_RS07645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ET948_RS07650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ET948_RS07730	COG0012	GTP binding
ET948_RS07735	COG0193	aminoacyl-tRNA hydrolase activity
ET948_RS07740	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ET948_RS07745	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ET948_RS07750	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ET948_RS07755	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ET948_RS07760	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ET948_RS07765	COG2890	protein-(glutamine-N5) methyltransferase activity
ET948_RS07770	COG3094	Invasion gene expression up-regulator, SirB
ET948_RS07775	COG2912	Transglutaminase-like superfamily
ET948_RS07780	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ET948_RS07785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ET948_RS07815	COG1393	Belongs to the ArsC family
ET948_RS07820	COG4783	chaperone-mediated protein folding
ET948_RS07840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ET948_RS07845	COG2716	regulation of RNA biosynthetic process
ET948_RS07855	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ET948_RS07865	COG1876	peptidase activity
ET948_RS07875	COG1393	Belongs to the ArsC family
ET948_RS07885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ET948_RS07890	COG1085	galactose-1-phosphate uridylyltransferase
ET948_RS07900	COG2017	converts alpha-aldose to the beta-anomer
ET948_RS07910	COG1609	Transcriptional regulator
ET948_RS07920	COG2182	Extracellular solute-binding protein
ET948_RS07925	COG1175	transmembrane transport
ET948_RS07930	COG3833	ABC-type maltose transport systems, permease component
ET948_RS07940	COG1874	Beta-galactosidase
ET948_RS07945	COG4580	involved in the transport of maltose and maltodextrins
ET948_RS07970	COG2837	iron assimilation
ET948_RS07980	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ET948_RS07985	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ET948_RS07990	COG1334	flagellar protein FlaG
ET948_RS07995	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ET948_RS08005	COG1516	flagellar protein fliS
ET948_RS08025	COG1677	Flagellar hook-basal body complex protein FliE
ET948_RS08035	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ET948_RS08085	COG1987	bacterial-type flagellum assembly
ET948_RS08100	COG2840	Smr protein MutS2
ET948_RS08105	COG2890	protein-(glutamine-N5) methyltransferase activity
ET948_RS08110	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ET948_RS08115	COG2860	membrane
ET948_RS08120	COG3101	peptidyl-lysine hydroxylation
ET948_RS08140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ET948_RS08145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ET948_RS08150	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ET948_RS08175	COG1346	cytolysis
ET948_RS08190	COG0596	Alpha beta hydrolase
ET948_RS08195	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ET948_RS08200	COG0033	Phosphoglucomutase
ET948_RS08210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ET948_RS08225	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ET948_RS08240	COG0567	Dehydrogenase, E1 component
ET948_RS08245	COG0508	dehydrogenase complex catalyzes the overall conversion of
ET948_RS08260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ET948_RS08265	COG1121	(ABC) transporter
ET948_RS08270	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ET948_RS08280	COG1918	ferrous iron import across plasma membrane
ET948_RS08300	COG0018	arginyl-trna synthetase
ET948_RS08305	COG3102	Protein conserved in bacteria
ET948_RS08310	COG1025	Belongs to the peptidase M16 family
ET948_RS08315	COG2062	phosphohistidine phosphatase, SixA
ET948_RS08345	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ET948_RS08350	COG2198	Histidine kinase
ET948_RS08350	COG0784	Response regulator, receiver
ET948_RS08350	COG0643	Histidine kinase
ET948_RS08355	COG2201	protein-glutamate methylesterase activity
ET948_RS08360	COG1192	Involved in chromosome partitioning
ET948_RS08370	COG0835	chemotaxis
ET948_RS08380	COG4133	protoheme IX ABC transporter activity
ET948_RS08385	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ET948_RS08390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ET948_RS08400	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ET948_RS08405	COG1138	Cytochrome C-type biogenesis protein
ET948_RS08410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ET948_RS08420	COG4235	cytochrome complex assembly
ET948_RS08425	COG2853	Lipoprotein
ET948_RS08445	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ET948_RS08455	COG0840	transmembrane signaling receptor activity
ET948_RS08475	COG3477	response to acidic pH
ET948_RS08480	COG0840	transmembrane signaling receptor activity
ET948_RS08495	COG3122	Protein conserved in bacteria
ET948_RS08505	COG2226	methyltransferase
ET948_RS08520	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ET948_RS08530	COG3139	Protein of unknown function (DUF1315)
ET948_RS08535	COG0252	asparaginase activity
ET948_RS08540	COG0616	signal peptide processing
ET948_RS08550	COG0788	formyltetrahydrofolate deformylase activity
ET948_RS08560	COG1199	ATP-dependent helicase activity
ET948_RS08565	COG1214	PFAM Peptidase M22, glycoprotease
ET948_RS08580	COG1073	alpha beta
ET948_RS08580	COG2226	methyltransferase
ET948_RS08585	COG0318	PFAM AMP-dependent synthetase and ligase
ET948_RS08590	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ET948_RS08595	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ET948_RS08600	COG2894	cell division
ET948_RS08605	COG0850	regulation of cytokinetic process
ET948_RS08610	COG3100	YcgL domain-containing protein
ET948_RS08615	COG2951	lytic endotransglycosylase activity
ET948_RS08620	COG0583	DNA-binding transcription factor activity
ET948_RS08625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ET948_RS08630	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ET948_RS08660	COG0583	DNA-binding transcription factor activity
ET948_RS08665	COG1518	maintenance of DNA repeat elements
ET948_RS08670	COG1203	CRISPR-associated helicase, Cas3
ET948_RS08700	COG0556	nucleotide-excision repair
ET948_RS08705	COG2204	response regulator
ET948_RS08710	COG2198	Histidine kinase
ET948_RS08715	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ET948_RS08720	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ET948_RS08725	COG0521	Mo-molybdopterin cofactor biosynthetic process
ET948_RS08735	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ET948_RS08740	COG0314	molybdopterin synthase activity
ET948_RS08745	COG0517	IMP dehydrogenase activity
ET948_RS08745	COG0617	tRNA 3'-terminal CCA addition
ET948_RS08745	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ET948_RS08765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ET948_RS08765	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ET948_RS08770	COG0489	protein tyrosine kinase activity
ET948_RS08775	COG0572	uridine kinase
ET948_RS08780	COG2982	Protein involved in outer membrane biogenesis
ET948_RS08785	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ET948_RS08795	COG2067	long-chain fatty acid transport protein
ET948_RS08800	COG0183	Belongs to the thiolase family
ET948_RS08805	COG1250	3-hydroxyacyl-CoA dehydrogenase
ET948_RS08805	COG1024	Enoyl-CoA hydratase
ET948_RS08810	COG0583	DNA-binding transcription factor activity
ET948_RS08815	COG0745	RESPONSE REGULATOR receiver
ET948_RS08825	COG2832	Protein of unknown function (DUF454)
ET948_RS08830	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ET948_RS08840	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ET948_RS08845	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ET948_RS08850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ET948_RS08860	COG2983	Belongs to the UPF0260 family
ET948_RS08870	COG3083	sulfuric ester hydrolase activity
ET948_RS08875	COG3082	Protein of unknown function (DUF1414)
ET948_RS08880	COG3081	Nucleoid-associated protein
ET948_RS08885	COG1757	Na H antiporter
ET948_RS08890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ET948_RS08895	COG2095	MarC family integral membrane protein
ET948_RS08900	COG1454	alcohol dehydrogenase
ET948_RS08900	COG1012	belongs to the aldehyde dehydrogenase family
ET948_RS08915	COG1530	ribonuclease E activity
ET948_RS08920	COG0564	pseudouridine synthase activity
ET948_RS08925	COG0424	maF-like protein
ET948_RS08930	COG1399	metal-binding, possibly nucleic acid-binding protein
ET948_RS08935	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ET948_RS08940	COG0416	fatty acid biosynthetic process
ET948_RS08945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ET948_RS08950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ET948_RS08960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ET948_RS08965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ET948_RS08970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ET948_RS08975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ET948_RS08980	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ET948_RS08985	COG0470	DNA polymerase III
ET948_RS08990	COG0084	hydrolase, TatD family'
ET948_RS08995	COG1263	PTS System
ET948_RS08995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET948_RS09010	COG0733	neurotransmitter:sodium symporter activity
ET948_RS09020	COG4667	esterase of the alpha-beta hydrolase superfamily
ET948_RS09030	COG1940	carbohydrate kinase activity
ET948_RS09035	COG0835	chemotaxis
ET948_RS09035	COG0784	Response regulator, receiver
ET948_RS09040	COG1028	Short-chain dehydrogenase reductase Sdr
ET948_RS09045	COG0616	signal peptide processing
ET948_RS09060	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ET948_RS09065	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ET948_RS09070	COG0436	Aminotransferase
ET948_RS09080	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ET948_RS09085	COG0596	Alpha beta hydrolase
ET948_RS09090	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ET948_RS09105	COG0477	Major facilitator Superfamily
ET948_RS09125	COG3015	lipoprotein NlpE involved in copper resistance
ET948_RS09130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ET948_RS09135	COG1522	sequence-specific DNA binding
ET948_RS09140	COG1946	Acyl-CoA thioesterase
ET948_RS09145	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ET948_RS09165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ET948_RS09170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ET948_RS09190	COG0747	negative chemotaxis
ET948_RS09195	COG0601	transmembrane transport
ET948_RS09200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET948_RS09210	COG1124	(ABC) transporter
ET948_RS09215	COG0840	transmembrane signaling receptor activity
ET948_RS09220	COG0366	Alpha amylase catalytic
ET948_RS09260	COG4964	Belongs to the GSP D family
ET948_RS09305	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ET948_RS09330	COG1741	Belongs to the pirin family
ET948_RS09335	COG0351	phosphomethylpyrimidine kinase
ET948_RS09340	COG4172	Belongs to the ABC transporter superfamily
ET948_RS09345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET948_RS09350	COG0601	transmembrane transport
ET948_RS09355	COG4166	transmembrane transport
ET948_RS09365	COG1538	Outer membrane efflux protein
ET948_RS09370	COG1566	PFAM secretion protein HlyD family protein
ET948_RS09375	COG2814	Major facilitator Superfamily
ET948_RS09380	COG2207	Transcriptional regulator
ET948_RS09380	COG3708	Transcriptional regulator
ET948_RS09390	COG1538	Outer membrane efflux protein
ET948_RS09400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ET948_RS09405	COG0745	RESPONSE REGULATOR receiver
ET948_RS09415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET948_RS09415	COG1263	PTS System
ET948_RS09425	COG1621	beta-fructofuranosidase activity
ET948_RS09435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ET948_RS09450	COG0601	transmembrane transport
ET948_RS09455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET948_RS09485	COG4964	Belongs to the GSP D family
ET948_RS09540	COG0435	Glutathione S-transferase
ET948_RS09545	COG0857	belongs to the CobB CobQ family
ET948_RS09545	COG0280	phosphate acetyltransferase
ET948_RS09550	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ET948_RS09555	COG3092	negative regulation of chromosome organization
ET948_RS09565	COG4120	Belongs to the binding-protein-dependent transport system permease family
ET948_RS09570	COG1122	ATPase activity
ET948_RS09575	COG3706	GGDEF domain
ET948_RS09585	COG0653	protein targeting
ET948_RS09590	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ET948_RS09595	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ET948_RS09600	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ET948_RS09605	COG0243	molybdopterin cofactor binding
ET948_RS09610	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ET948_RS09610	COG1648	precorrin-2 dehydrogenase activity
ET948_RS09630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ET948_RS09635	COG1116	anion transmembrane transporter activity
ET948_RS09640	COG2146	nitrite reductase [NAD(P)H] activity
ET948_RS09640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ET948_RS09655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ET948_RS09660	COG0156	8-amino-7-oxononanoate synthase activity
ET948_RS09670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ET948_RS09675	COG0501	Belongs to the peptidase M48B family
ET948_RS09680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ET948_RS09685	COG2915	High frequency lysogenization protein hflD homolog
ET948_RS09690	COG0482	sulfurtransferase activity
ET948_RS09695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ET948_RS09700	COG2916	Histone family protein nucleoid-structuring protein H-NS
ET948_RS09705	COG1757	Na H antiporter
ET948_RS09710	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ET948_RS09715	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ET948_RS09720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ET948_RS09725	COG0131	Imidazoleglycerol-phosphate dehydratase
ET948_RS09725	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ET948_RS09730	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ET948_RS09735	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ET948_RS09740	COG0107	imidazoleglycerol-phosphate synthase activity
ET948_RS09745	COG0140	phosphoribosyl-ATP diphosphatase activity
ET948_RS09745	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ET948_RS09750	COG1187	pseudouridine synthase activity
ET948_RS09780	COG0456	acetyltransferase
ET948_RS09785	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ET948_RS09790	COG0072	phenylalanine-tRNA ligase activity
ET948_RS09790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ET948_RS09795	COG0776	regulation of translation
ET948_RS09805	COG0500	methyltransferase
ET948_RS09815	COG5001	Diguanylate cyclase
ET948_RS09815	COG3300	MHYT domain
ET948_RS09820	COG0295	cytidine deaminase activity
ET948_RS09825	COG1346	cytolysis
ET948_RS09830	COG1380	Effector of murein hydrolase LrgA
ET948_RS09835	COG2925	Exonuclease
ET948_RS09840	COG1823	symporter activity
ET948_RS09845	COG0702	epimerase
ET948_RS09850	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ET948_RS09855	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ET948_RS09875	COG4139	cobalamin transport
ET948_RS09880	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
ET948_RS09895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ET948_RS09925	COG0583	DNA-binding transcription factor activity
ET948_RS09935	COG1451	nucleotide metabolic process
ET948_RS09945	COG3063	Type IV pilus biogenesis stability protein PilW
ET948_RS09950	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ET948_RS09965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ET948_RS09980	COG0784	Response regulator, receiver
ET948_RS09980	COG0835	chemotaxis
ET948_RS09990	COG2199	diguanylate cyclase activity
ET948_RS10010	COG0281	malic enzyme
ET948_RS10015	COG1053	succinate dehydrogenase
ET948_RS10020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ET948_RS10025	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ET948_RS10035	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ET948_RS10045	COG1805	sodium ion transport
ET948_RS10050	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ET948_RS10060	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ET948_RS10075	COG3290	protein histidine kinase activity
ET948_RS10080	COG1271	oxidase subunit
ET948_RS10085	COG1294	oxidase, subunit
ET948_RS10090	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ET948_RS10095	COG1254	Belongs to the acylphosphatase family
ET948_RS10100	COG2920	part of a sulfur-relay system
ET948_RS10105	COG0670	Belongs to the BI1 family
ET948_RS10110	COG1126	abc transporter atp-binding protein
ET948_RS10115	COG0765	amino acid transport
ET948_RS10120	COG4597	amino acid ABC transporter
ET948_RS10125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET948_RS10135	COG0561	phosphatase activity
ET948_RS10140	COG0602	queuosine metabolic process
ET948_RS10145	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ET948_RS10165	COG0443	Heat shock 70 kDa protein
ET948_RS10170	COG0443	Heat shock 70 kDa protein
ET948_RS10200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ET948_RS10205	COG1643	Atp-dependent helicase
ET948_RS10215	COG0583	DNA-binding transcription factor activity
ET948_RS10220	COG0477	Major facilitator Superfamily
ET948_RS10235	COG2200	EAL domain
ET948_RS10245	COG0584	glycerophosphoryl diester phosphodiesterase
ET948_RS10250	COG1349	DNA-binding transcription factor activity
ET948_RS10255	COG3842	ATPase activity
ET948_RS10260	COG0395	ABC-type sugar transport system, permease component
ET948_RS10265	COG1175	transmembrane transport
ET948_RS10275	COG0840	transmembrane signaling receptor activity
ET948_RS10290	COG0643	Histidine kinase
ET948_RS10290	COG2198	Histidine kinase
ET948_RS10300	COG0835	chemotaxis
ET948_RS10305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ET948_RS10310	COG2201	protein-glutamate methylesterase activity
ET948_RS10320	COG0811	peptide transport
ET948_RS10325	COG0811	peptide transport
ET948_RS10330	COG0848	biopolymer transport protein
ET948_RS10345	COG4667	esterase of the alpha-beta hydrolase superfamily
ET948_RS10350	COG1793	dna ligase
ET948_RS10360	COG0307	riboflavin synthase, alpha
ET948_RS10370	COG0393	Putative heavy-metal-binding
ET948_RS10375	COG3001	Fructosamine kinase
ET948_RS10385	COG0791	NLP P60 protein
ET948_RS10390	COG3148	PFAM DTW domain containing protein
ET948_RS10395	COG1940	carbohydrate kinase activity
ET948_RS10405	COG0303	'Molybdopterin
ET948_RS10410	COG0746	molybdenum cofactor guanylyltransferase activity
ET948_RS10415	COG1136	(ABC) transporter
ET948_RS10420	COG4662	Binding-protein-dependent transport system inner membrane component
ET948_RS10430	COG2204	response regulator
ET948_RS10435	COG3852	Histidine kinase
ET948_RS10440	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ET948_RS10470	COG3383	formate dehydrogenase (NAD+) activity
ET948_RS10470	COG0243	molybdopterin cofactor binding
ET948_RS10475	COG0437	4 iron, 4 sulfur cluster binding
ET948_RS10490	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ET948_RS10495	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ET948_RS10505	COG1177	transmembrane transport
ET948_RS10515	COG3842	ATPase activity
ET948_RS10540	COG0589	response to stress
ET948_RS10545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ET948_RS10560	COG2217	Heavy metal translocating P-type atpase
ET948_RS10570	COG2010	Cytochrome c
ET948_RS10585	COG3278	Belongs to the heme-copper respiratory oxidase family
ET948_RS10600	COG0784	Response regulator, receiver
ET948_RS10600	COG2205	protein histidine kinase activity
ET948_RS10605	COG2873	o-acetylhomoserine
ET948_RS10610	COG3140	Belongs to the UPF0181 family
ET948_RS10625	COG0745	RESPONSE REGULATOR receiver
ET948_RS10635	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ET948_RS10640	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ET948_RS10655	COG3706	GGDEF domain
ET948_RS10660	COG0189	ligase activity
ET948_RS10660	COG4067	protein conserved in archaea
ET948_RS10670	COG0602	queuosine metabolic process
ET948_RS10675	COG1328	CTP reductase activity
ET948_RS10690	COG0640	Transcriptional regulator
ET948_RS10720	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ET948_RS10760	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ET948_RS10770	COG0494	nUDIX hydrolase
ET948_RS10780	COG0183	Belongs to the thiolase family
ET948_RS10790	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ET948_RS10795	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ET948_RS10800	COG1012	belongs to the aldehyde dehydrogenase family
ET948_RS10815	COG1414	Transcriptional regulator
ET948_RS10820	COG1309	transcriptional regulator
ET948_RS10825	COG0513	Belongs to the DEAD box helicase family
ET948_RS10830	COG0814	amino acid
ET948_RS10835	COG0840	transmembrane signaling receptor activity
ET948_RS10840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ET948_RS10845	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ET948_RS10850	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ET948_RS10855	COG1984	allophanate hydrolase subunit 2
ET948_RS10870	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ET948_RS10875	COG4181	ATPase activity
ET948_RS10885	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ET948_RS10895	COG0484	heat shock protein binding
ET948_RS10910	COG0546	phosphoglycolate phosphatase activity
ET948_RS10925	COG5001	Diguanylate cyclase
ET948_RS10935	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ET948_RS10950	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ET948_RS10950	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ET948_RS10960	COG1278	Cold shock
ET948_RS10975	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ET948_RS10985	COG0814	amino acid
ET948_RS10995	COG3313	Fe-S protein
ET948_RS11005	COG0116	Belongs to the methyltransferase superfamily
ET948_RS11005	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ET948_RS11010	COG0564	pseudouridine synthase activity
ET948_RS11015	COG0733	neurotransmitter:sodium symporter activity
ET948_RS11025	COG0626	cystathionine gamma-synthase activity
ET948_RS11030	COG0519	Catalyzes the synthesis of GMP from XMP
ET948_RS11035	COG1983	PspC domain protein
ET948_RS11045	COG1842	Phage shock protein A
ET948_RS11050	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ET948_RS11075	COG4172	Belongs to the ABC transporter superfamily
ET948_RS11085	COG1227	inorganic diphosphatase activity
ET948_RS11090	COG2116	formate transmembrane transporter activity
ET948_RS11100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ET948_RS11105	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ET948_RS11110	COG1435	thymidine kinase activity
ET948_RS11120	COG1801	Protein of unknown function DUF72
ET948_RS11125	COG4106	trans-aconitate 2-methyltransferase activity
ET948_RS11130	COG0500	methyltransferase
ET948_RS11135	COG4067	protein conserved in archaea
ET948_RS11135	COG0189	ligase activity
ET948_RS11145	COG0189	ligase activity
ET948_RS11155	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ET948_RS11160	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
ET948_RS11165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ET948_RS11170	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ET948_RS11175	COG1609	Transcriptional regulator
ET948_RS11180	COG3070	regulator of competence-specific genes
ET948_RS11190	COG0297	glycogen (starch) synthase activity
ET948_RS11195	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ET948_RS11200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ET948_RS11215	COG3134	Outer membrane lipoprotein
ET948_RS11220	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ET948_RS11225	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ET948_RS11230	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ET948_RS11235	COG0542	response to heat
ET948_RS11240	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ET948_RS11245	COG1278	Cold shock
ET948_RS11255	COG0322	excinuclease ABC activity
ET948_RS11260	COG2197	response regulator
ET948_RS11275	COG0417	DNA replication proofreading
ET948_RS11280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ET948_RS11290	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ET948_RS11295	COG3099	Belongs to the UPF0263 family
ET948_RS11300	COG3097	Belongs to the UPF0267 family
ET948_RS11315	COG0277	FAD linked oxidase domain protein
ET948_RS11315	COG0247	lactate metabolic process
ET948_RS11330	COG2885	chlorophyll binding
ET948_RS11355	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ET948_RS11365	COG1643	Atp-dependent helicase
ET948_RS11370	COG0281	malic enzyme
ET948_RS11380	COG2949	membrane
ET948_RS11400	COG0492	ferredoxin-NADP+ reductase activity
ET948_RS11405	COG4988	ABC transporter
ET948_RS11410	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ET948_RS11420	COG1187	pseudouridine synthase activity
ET948_RS11425	COG0009	L-threonylcarbamoyladenylate synthase
ET948_RS11430	COG0613	PHP domain protein
ET948_RS11440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ET948_RS11445	COG0512	Glutamine amidotransferase of anthranilate synthase
ET948_RS11450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ET948_RS11455	COG0134	indole-3-glycerol-phosphate synthase activity
ET948_RS11455	COG0135	phosphoribosylanthranilate isomerase activity
ET948_RS11460	COG0133	tryptophan synthase activity
ET948_RS11465	COG0159	tryptophan synthase activity
ET948_RS11470	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ET948_RS11480	COG1607	acyl-coa hydrolase
ET948_RS11485	COG2350	Protein conserved in bacteria
ET948_RS11495	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ET948_RS11500	COG0583	DNA-binding transcription factor activity
ET948_RS11515	COG0612	Peptidase, M16
ET948_RS11525	COG1032	radical SAM domain protein
ET948_RS11535	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ET948_RS11545	COG3852	Histidine kinase
ET948_RS11560	COG3070	regulator of competence-specific genes
ET948_RS11570	COG2431	L-lysine efflux transmembrane transporter activity
ET948_RS11580	COG0076	glutamate decarboxylase activity
ET948_RS11585	COG1737	Transcriptional regulator
ET948_RS11595	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ET948_RS11600	COG3273	potassium ion transport
ET948_RS11600	COG2985	domain, Protein
ET948_RS11605	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ET948_RS11610	COG1960	acyl-CoA dehydrogenase activity
ET948_RS11630	COG1012	belongs to the aldehyde dehydrogenase family
ET948_RS11650	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ET948_RS11655	COG0640	Transcriptional regulator
ET948_RS11665	COG0573	inorganic phosphate transmembrane transporter activity
ET948_RS11675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ET948_RS11685	COG0798	PFAM Bile acid sodium symporter
ET948_RS11715	COG0640	Transcriptional regulator
ET948_RS11720	COG0659	secondary active sulfate transmembrane transporter activity
ET948_RS11740	COG4139	cobalamin transport
ET948_RS11750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET948_RS11765	COG0531	amino acid
ET948_RS11775	COG4948	Mandelate Racemase Muconate Lactonizing
ET948_RS11790	COG1115	amino acid carrier protein
ET948_RS11795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ET948_RS11835	COG4656	Part of a membrane complex involved in electron transport
ET948_RS11840	COG2878	Part of a membrane complex involved in electron transport
ET948_RS11845	COG4657	Part of a membrane complex involved in electron transport
ET948_RS11920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ET948_RS11980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ET948_RS11985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ET948_RS11990	COG1882	Formate acetyltransferase
ET948_RS11995	COG1349	DNA-binding transcription factor activity
ET948_RS12000	COG1263	PTS System
ET948_RS12000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET948_RS12005	COG1486	melibiose metabolic process
ET948_RS12010	COG2188	Transcriptional regulator
ET948_RS12045	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ET948_RS12050	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ET948_RS12055	COG2885	chlorophyll binding
ET948_RS12060	COG0823	Involved in the tonB-independent uptake of proteins
ET948_RS12075	COG0811	peptide transport
ET948_RS12080	COG0824	Thioesterase
ET948_RS12090	COG4890	Cyd operon protein YbgT
ET948_RS12095	COG1294	oxidase, subunit
ET948_RS12100	COG1271	oxidase subunit
ET948_RS12110	COG0632	four-way junction helicase activity
ET948_RS12115	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ET948_RS12120	COG0215	cysteine-tRNA ligase activity
ET948_RS12125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ET948_RS12130	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ET948_RS12135	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ET948_RS12140	COG3012	SEC-C Motif Domain Protein
ET948_RS12145	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ET948_RS12155	COG1199	ATP-dependent helicase activity
ET948_RS12160	COG0730	response to heat
ET948_RS12175	COG0708	Exodeoxyribonuclease III
ET948_RS12205	COG1882	Formate acetyltransferase
ET948_RS12210	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ET948_RS12215	COG3013	Belongs to the UPF0304 family
ET948_RS12225	COG2766	serine protein kinase
ET948_RS12230	COG2718	Belongs to the UPF0229 family
ET948_RS12235	COG2719	SpoVR family
ET948_RS12240	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ET948_RS12250	COG1663	tetraacyldisaccharide 4'-kinase activity
ET948_RS12255	COG1132	(ABC) transporter
ET948_RS12260	COG0658	competence protein
ET948_RS12260	COG2333	competence protein COMEC
ET948_RS12270	COG2249	NAD(P)H dehydrogenase (quinone) activity
ET948_RS12280	COG4591	ABC-type transport system involved in lipoprotein release permease component
ET948_RS12285	COG1136	(ABC) transporter
ET948_RS12290	COG4591	ABC-type transport system involved in lipoprotein release permease component
ET948_RS12300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ET948_RS12320	COG2366	antibiotic biosynthetic process
ET948_RS12330	COG1120	ATPase activity
ET948_RS12335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ET948_RS12345	COG1629	transport
ET948_RS12345	COG4774	siderophore transport
ET948_RS12350	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET948_RS12355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET948_RS12360	COG4592	Periplasmic binding protein
ET948_RS12380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ET948_RS12380	COG2226	methyltransferase
ET948_RS12380	COG3433	isochorismatase activity
ET948_RS12385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ET948_RS12390	COG1028	Short-chain dehydrogenase reductase Sdr
ET948_RS12395	COG1169	isochorismate synthase
ET948_RS12400	COG1021	2,3-dihydroxybenzoate-AMP ligase
ET948_RS12405	COG1252	NADH dehydrogenase
ET948_RS12435	COG0537	adenosine 5'-monophosphoramidase activity
ET948_RS12440	COG0840	transmembrane signaling receptor activity
ET948_RS12450	COG2186	Transcriptional regulator
ET948_RS12455	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ET948_RS12470	COG1674	ftsk spoiiie
ET948_RS12475	COG1522	sequence-specific DNA binding
ET948_RS12480	COG0686	Belongs to the AlaDH PNT family
ET948_RS12490	COG0583	DNA-binding transcription factor activity
ET948_RS12505	COG0284	orotidine-5'-phosphate decarboxylase activity
ET948_RS12510	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ET948_RS12515	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ET948_RS12520	COG0776	regulation of translation
ET948_RS12525	COG0539	negative regulation of cytoplasmic translation
ET948_RS12530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ET948_RS12540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ET948_RS12545	COG0776	regulation of translation
ET948_RS12550	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ET948_RS12555	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ET948_RS12565	COG0544	peptidyl-prolyl cis-trans isomerase activity
ET948_RS12570	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ET948_RS12575	COG1760	l-serine dehydratase
ET948_RS12580	COG2985	domain, Protein
ET948_RS12590	COG3153	acetyltransferase
ET948_RS12590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ET948_RS12605	COG0840	transmembrane signaling receptor activity
ET948_RS12610	COG4657	Part of a membrane complex involved in electron transport
ET948_RS12615	COG2878	Part of a membrane complex involved in electron transport
ET948_RS12620	COG4656	Part of a membrane complex involved in electron transport
ET948_RS12625	COG4658	electron transport chain
ET948_RS12630	COG4659	FMN binding
ET948_RS12635	COG4660	Part of a membrane complex involved in electron transport
ET948_RS12640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ET948_RS12645	COG0346	lactoylglutathione lyase activity
ET948_RS12660	COG2056	Na+-H+ antiporter family
ET948_RS12665	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ET948_RS12670	COG1286	toxin biosynthetic process
ET948_RS12675	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ET948_RS12680	COG0285	dihydrofolate synthase activity
ET948_RS12685	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ET948_RS12690	COG0101	tRNA pseudouridine synthase activity
ET948_RS12705	COG1263	PTS System
ET948_RS12705	COG2190	(PTS) system
ET948_RS12705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET948_RS12710	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ET948_RS12715	COG1846	Transcriptional regulator
ET948_RS12715	COG1940	carbohydrate kinase activity
ET948_RS12730	COG0367	asparagine synthase
ET948_RS12735	COG0250	Participates in transcription elongation, termination and antitermination
ET948_RS12745	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ET948_RS12755	COG0326	Molecular chaperone. Has ATPase activity
ET948_RS12760	COG3710	Transcriptional regulator
ET948_RS12770	COG0622	Phosphoesterase
ET948_RS12775	COG1090	epimerase
ET948_RS12780	COG0300	oxidoreductase activity
ET948_RS12785	COG3118	belongs to the thioredoxin family
ET948_RS12790	COG0330	HflC and HflK could
ET948_RS12795	COG1585	Membrane protein implicated in regulation of membrane protease activity
ET948_RS12800	COG0789	Transcriptional regulator
ET948_RS12815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ET948_RS12820	COG3115	cell septum assembly
ET948_RS12825	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ET948_RS12830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ET948_RS12840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET948_RS12850	COG2190	(PTS) system
ET948_RS12855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ET948_RS12860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ET948_RS12865	COG1702	phosphate starvation-inducible protein PhoH
ET948_RS12870	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ET948_RS12875	COG4535	Mg2 and Co2 transporter CorC
ET948_RS12880	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ET948_RS12885	COG2888	peptidyl-tyrosine sulfation
ET948_RS12890	COG0495	leucyl-tRNA aminoacylation
ET948_RS12895	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ET948_RS12900	COG1466	dna polymerase III delta subunit
ET948_RS12905	COG0799	negative regulation of ribosome biogenesis
ET948_RS12910	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ET948_RS12915	COG0768	penicillin binding
ET948_RS12920	COG0772	Belongs to the SEDS family
ET948_RS12925	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ET948_RS12930	COG1686	Belongs to the peptidase S11 family
ET948_RS12935	COG2921	Belongs to the UPF0250 family
ET948_RS12945	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ET948_RS12965	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ET948_RS12975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ET948_RS13005	COG0366	Alpha amylase catalytic
ET948_RS13010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET948_RS13010	COG1263	PTS System
ET948_RS13015	COG1609	Transcriptional regulator
ET948_RS13020	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ET948_RS13030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ET948_RS13035	COG2146	nitrite reductase [NAD(P)H] activity
ET948_RS13040	COG2116	formate transmembrane transporter activity
ET948_RS13080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ET948_RS13095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ET948_RS13100	COG0625	glutathione transferase activity
ET948_RS13105	COG0583	DNA-binding transcription factor activity
ET948_RS13110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ET948_RS13115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ET948_RS13125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ET948_RS13135	COG1596	polysaccharide export
ET948_RS13165	COG0297	glycogen (starch) synthase activity
ET948_RS13165	COG0438	transferase activity, transferring glycosyl groups
ET948_RS13180	COG0247	lactate metabolic process
ET948_RS13185	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
ET948_RS13190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ET948_RS13195	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ET948_RS13210	COG2926	Belongs to the UPF0265 family
ET948_RS13220	COG3132	Protein of unknown function, DUF480
ET948_RS13225	COG2827	Endonuclease containing a URI domain
ET948_RS13240	COG0725	ABC transporter, periplasmic molybdate-binding protein
ET948_RS13245	COG4149	molybdate abc transporter
ET948_RS13250	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ET948_RS13265	COG1289	transmembrane transporter activity
ET948_RS13270	COG0210	DNA helicase
ET948_RS13275	COG1335	isochorismatase
ET948_RS13285	COG1803	Methylglyoxal synthase
ET948_RS13290	COG1979	alcohol dehydrogenase
ET948_RS13300	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ET948_RS13315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ET948_RS13320	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ET948_RS13325	COG0840	transmembrane signaling receptor activity
ET948_RS13330	COG0840	transmembrane signaling receptor activity
ET948_RS13335	COG0437	4 iron, 4 sulfur cluster binding
ET948_RS13340	COG0348	domain, Protein
ET948_RS13350	COG3005	denitrification pathway
ET948_RS13360	COG0243	molybdopterin cofactor binding
ET948_RS13375	COG3850	Histidine kinase
ET948_RS13380	COG2197	response regulator
ET948_RS13385	COG3069	C4-dicarboxylate transmembrane transporter activity
ET948_RS13395	COG0456	acetyltransferase
ET948_RS13400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ET948_RS13420	COG0840	transmembrane signaling receptor activity
ET948_RS13425	COG0778	Nitroreductase
ET948_RS13455	COG0515	serine threonine protein kinase
ET948_RS13455	COG2815	serine threonine protein kinase
ET948_RS13490	COG0631	protein serine/threonine phosphatase activity
ET948_RS13560	COG3209	COG3209 Rhs family protein
ET948_RS13595	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ET948_RS13600	COG1061	Type III restriction enzyme res subunit
ET948_RS13605	COG1187	pseudouridine synthase activity
ET948_RS13610	COG2814	Major facilitator Superfamily
ET948_RS13620	COG0702	epimerase
ET948_RS13625	COG0534	Mate efflux family protein
ET948_RS13630	COG4181	ATPase activity
ET948_RS13650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ET948_RS13650	COG2111	Na H antiporter
ET948_RS13655	COG2111	Na H antiporter
ET948_RS13660	COG1006	Multisubunit Na H antiporter MnhC subunit
ET948_RS13670	COG1863	multisubunit Na H antiporter MnhE subunit
ET948_RS13675	COG2212	antiporter activity
ET948_RS13680	COG1320	monovalent cation:proton antiporter activity
ET948_RS13690	COG1748	Saccharopine dehydrogenase
ET948_RS13725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ET948_RS13730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ET948_RS13750	COG2989	Protein conserved in bacteria
ET948_RS13755	COG3108	Peptidase M15
ET948_RS13760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ET948_RS13775	COG1846	Transcriptional regulator
ET948_RS13780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ET948_RS13785	COG0840	transmembrane signaling receptor activity
ET948_RS13790	COG2176	DNA-directed DNA polymerase activity
ET948_RS13795	COG0517	IMP dehydrogenase activity
ET948_RS13800	COG1448	Aminotransferase
ET948_RS13805	COG0017	Asparaginyl-tRNA synthetase
ET948_RS13810	COG0720	synthase
ET948_RS13820	COG0577	efflux transmembrane transporter activity
ET948_RS13820	COG1136	(ABC) transporter
ET948_RS13825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ET948_RS13830	COG1760	l-serine dehydratase
ET948_RS13835	COG0814	amino acid
ET948_RS13840	COG0494	nUDIX hydrolase
ET948_RS13845	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ET948_RS13860	COG3106	COG3106 Predicted ATPase
ET948_RS13875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ET948_RS13885	COG5006	permease, DMT superfamily
ET948_RS13900	COG0471	metal ion transport
ET948_RS13905	COG4191	Histidine kinase
ET948_RS13905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET948_RS13915	COG2991	Protein conserved in bacteria
ET948_RS13930	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ET948_RS13935	COG0372	Belongs to the citrate synthase family
ET948_RS13945	COG2828	Protein conserved in bacteria
ET948_RS13975	COG1966	Carbon starvation protein
ET948_RS13985	COG0003	Pfam Anion-transporting ATPase
ET948_RS13995	COG1115	amino acid carrier protein
ET948_RS14005	COG1666	GTP binding
ET948_RS14010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ET948_RS14015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ET948_RS14030	COG2996	Protein conserved in bacteria
ET948_RS14040	COG3008	intermembrane lipid transfer
ET948_RS14045	COG2995	paraquat-inducible protein a
ET948_RS14050	COG1956	GAF domain-containing protein
ET948_RS14055	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
ET948_RS14065	COG0308	aminopeptidase N
ET948_RS14075	COG2902	Dehydrogenase
ET948_RS14080	COG0167	dihydroorotate dehydrogenase activity
ET948_RS14090	COG0116	Belongs to the methyltransferase superfamily
ET948_RS14090	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ET948_RS14100	COG0488	(ABC) transporter
ET948_RS14115	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ET948_RS14120	COG1067	ATP-dependent peptidase activity
ET948_RS14125	COG3120	sequence-specific DNA binding
ET948_RS14140	COG0023	Translation Initiation Factor
ET948_RS14160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ET948_RS14160	COG1042	CoA-binding domain protein
ET948_RS14160	COG0045	succinate-CoA ligase (ADP-forming) activity
ET948_RS14165	COG0583	DNA-binding transcription factor activity
ET948_RS14170	COG4533	DNA binding
ET948_RS14180	COG2050	protein possibly involved in aromatic compounds catabolism
ET948_RS14190	COG2824	Alkylphosphonate utilization operon protein PhnA
ET948_RS14200	COG0861	Integral membrane protein TerC family
ET948_RS14210	COG3593	DNA synthesis involved in DNA repair
ET948_RS14220	COG0583	DNA-binding transcription factor activity
ET948_RS14225	COG2116	formate transmembrane transporter activity
ET948_RS14235	COG3038	cytochrome b561
ET948_RS14245	COG0517	IMP dehydrogenase activity
ET948_RS14260	COG0673	inositol 2-dehydrogenase activity
ET948_RS14265	COG2610	gluconate transmembrane transporter activity
ET948_RS14270	COG1454	alcohol dehydrogenase
ET948_RS14280	COG0840	transmembrane signaling receptor activity
ET948_RS14295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ET948_RS14300	COG3962	Belongs to the TPP enzyme family
ET948_RS14305	COG3718	enzyme involved in inositol metabolism
ET948_RS14315	COG2176	DNA-directed DNA polymerase activity
ET948_RS14320	COG0517	IMP dehydrogenase activity
ET948_RS14320	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ET948_RS14325	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ET948_RS14330	COG0673	inositol 2-dehydrogenase activity
ET948_RS14335	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ET948_RS14340	COG1172	Belongs to the binding-protein-dependent transport system permease family
ET948_RS14350	COG1129	ABC transporter
ET948_RS14360	COG0488	(ABC) transporter
ET948_RS14365	COG0826	peptidase U32
ET948_RS14375	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ET948_RS14405	COG0765	amino acid transport
ET948_RS14410	COG0765	amino acid transport
ET948_RS14415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET948_RS14425	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ET948_RS14430	COG0523	cobalamin synthesis protein
ET948_RS14455	COG0156	8-amino-7-oxononanoate synthase activity
ET948_RS14460	COG2205	protein histidine kinase activity
ET948_RS14460	COG0784	Response regulator, receiver
ET948_RS14465	COG0419	ATPase involved in DNA repair
ET948_RS14470	COG0420	3'-5' exonuclease activity
ET948_RS14475	COG1609	Transcriptional regulator
ET948_RS14480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET948_RS14480	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET948_RS14485	COG1105	Belongs to the carbohydrate kinase PfkB family
ET948_RS14490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ET948_RS14490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ET948_RS14490	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ET948_RS14495	COG1609	Transcriptional regulator
ET948_RS14500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET948_RS14520	COG0589	response to stress
ET948_RS14525	COG2501	S4 domain
ET948_RS14535	COG4172	Belongs to the ABC transporter superfamily
ET948_RS14540	COG4239	(ABC) transporter, permease
ET948_RS14545	COG4174	ABC transporter (Permease)
ET948_RS14550	COG4166	transmembrane transport
ET948_RS14575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ET948_RS14580	COG1011	Hydrolase
ET948_RS14585	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ET948_RS14605	COG2897	thiosulfate sulfurtransferase activity
ET948_RS14610	COG3738	Protein conserved in bacteria
ET948_RS14615	COG5433	transposase activity
ET948_RS14670	COG2801	Transposase and inactivated derivatives
ET948_RS14710	COG5433	transposase activity
ET948_RS14785	COG2433	Pfam Transposase IS66
ET948_RS14805	COG2801	Transposase and inactivated derivatives
ET948_RS14885	COG0582	viral genome integration into host DNA
ET948_RS14950	COG0582	viral genome integration into host DNA
ET948_RS14955	COG2801	Transposase and inactivated derivatives
ET948_RS14980	COG4977	sequence-specific DNA binding
ET948_RS15010	COG3335	DDE superfamily endonuclease
ET948_RS15045	COG0346	lactoylglutathione lyase activity
ET948_RS15060	COG2801	Transposase and inactivated derivatives
ET948_RS15090	COG2801	Transposase and inactivated derivatives
ET948_RS15110	COG5433	transposase activity
ET948_RS15120	COG2944	sequence-specific DNA binding
ET948_RS15125	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ET948_RS15220	COG5433	transposase activity
ET948_RS15265	COG2801	Transposase and inactivated derivatives
ET948_RS15300	COG2801	Transposase and inactivated derivatives
ET948_RS15400	COG2801	Transposase and inactivated derivatives
ET948_RS15470	COG3335	DDE superfamily endonuclease
ET948_RS15480	COG0582	viral genome integration into host DNA
ET948_RS15500	COG0346	lactoylglutathione lyase activity
ET948_RS15570	COG2801	Transposase and inactivated derivatives
ET948_RS15595	COG0454	-acetyltransferase
ET948_RS15790	COG5433	transposase activity
ET948_RS15820	COG0346	lactoylglutathione lyase activity
ET948_RS15830	COG2801	Transposase and inactivated derivatives
ET948_RS15860	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ET948_RS15865	COG0513	Belongs to the DEAD box helicase family
ET948_RS15915	COG2723	6-phospho-beta-galactosidase activity
ET948_RS15930	COG1263	PTS System
ET948_RS15930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET948_RS15930	COG2190	(PTS) system
ET948_RS15935	COG1785	Belongs to the alkaline phosphatase family
ET948_RS15950	COG0527	aspartate kinase activity
ET948_RS15955	COG0662	Cupin 2, conserved barrel domain protein
ET948_RS15960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ET948_RS15965	COG0456	acetyltransferase
ET948_RS15970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ET948_RS15990	COG1765	OsmC-like protein
ET948_RS16005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ET948_RS16010	COG1151	hydroxylamine reductase activity
ET948_RS16025	COG1522	sequence-specific DNA binding
ET948_RS16030	COG0531	amino acid
ET948_RS16040	COG1278	Cold shock
ET948_RS16050	COG4145	pantothenate transmembrane transporter activity
ET948_RS16070	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ET948_RS16085	COG1482	cell wall glycoprotein biosynthetic process
ET948_RS16090	COG0840	transmembrane signaling receptor activity
ET948_RS16095	COG4580	involved in the transport of maltose and maltodextrins
ET948_RS16100	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ET948_RS16105	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ET948_RS16115	COG1609	Transcriptional regulator
ET948_RS16135	COG0395	ABC-type sugar transport system, permease component
ET948_RS16140	COG1175	transmembrane transport
ET948_RS16190	COG0633	Ferredoxin
ET948_RS16190	COG3217	Mosc domain protein beta barrel domain protein
ET948_RS16210	COG1349	DNA-binding transcription factor activity
ET948_RS16235	COG3833	ABC-type maltose transport systems, permease component
ET948_RS16240	COG1175	transmembrane transport
ET948_RS16250	COG3842	ATPase activity
ET948_RS16255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ET948_RS16270	COG1461	Dihydroxyacetone kinase
ET948_RS16275	COG2376	Dihydroxyacetone kinase
ET948_RS16295	COG1063	alcohol dehydrogenase
ET948_RS16300	COG0156	8-amino-7-oxononanoate synthase activity
ET948_RS16315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ET948_RS16325	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ET948_RS16330	COG0363	glucosamine-6-phosphate deaminase activity
ET948_RS16335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ET948_RS16350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ET948_RS16355	COG2205	protein histidine kinase activity
ET948_RS16355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET948_RS16365	COG3300	MHYT domain
ET948_RS16365	COG5001	Diguanylate cyclase
ET948_RS16380	COG3188	usher protein
ET948_RS16390	COG3121	Chaperone
ET948_RS16415	COG0673	inositol 2-dehydrogenase activity
ET948_RS16420	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ET948_RS16430	COG1120	ATPase activity
ET948_RS16435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET948_RS16440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET948_RS16445	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ET948_RS16450	COG4774	siderophore transport
ET948_RS16465	COG1342	Belongs to the UPF0251 family
ET948_RS16470	COG1846	Transcriptional regulator
ET948_RS16475	COG1566	PFAM secretion protein HlyD family protein
ET948_RS16485	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ET948_RS16495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ET948_RS16500	COG2259	Doxx family
ET948_RS16505	COG0786	glutamate:sodium symporter activity
ET948_RS16510	COG0786	glutamate:sodium symporter activity
ET948_RS16515	COG1376	ErfK ybiS ycfS ynhG family protein
ET948_RS16515	COG1388	LysM domain
ET948_RS16520	COG0415	Belongs to the DNA photolyase family
ET948_RS16525	COG0789	Transcriptional regulator
ET948_RS16530	COG3272	Protein of unknown function (DUF1722)
ET948_RS16535	COG0813	purine-nucleoside phosphorylase activity
ET948_RS16545	COG2909	trisaccharide binding
ET948_RS16565	COG1999	signal sequence binding
ET948_RS16575	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ET948_RS16600	COG4580	involved in the transport of maltose and maltodextrins
ET948_RS16610	COG1132	(ABC) transporter
ET948_RS16625	COG3383	formate dehydrogenase (NAD+) activity
ET948_RS16630	COG0010	Belongs to the arginase family
ET948_RS16645	COG0840	transmembrane signaling receptor activity
ET948_RS16655	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ET948_RS16660	COG0471	metal ion transport
ET948_RS16670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ET948_RS16675	COG1640	4-alpha-glucanotransferase
ET948_RS16680	COG0058	SHG alpha-glucan phosphorylase activity
ET948_RS16685	COG2909	trisaccharide binding
ET948_RS16700	COG2207	Transcriptional regulator
ET948_RS16705	COG1454	alcohol dehydrogenase
ET948_RS16715	COG0471	metal ion transport
ET948_RS16720	COG2207	Transcriptional regulator
ET948_RS16730	COG0446	pyridine nucleotide-disulphide oxidoreductase
ET948_RS16735	COG2184	nucleotidyltransferase activity
ET948_RS16740	COG1444	tRNA N-acetyltransferase activity
ET948_RS16745	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ET948_RS16775	COG0217	transcriptional regulatory protein
ET948_RS16780	COG2084	Dehydrogenase
ET948_RS16795	COG0259	pyridoxamine-phosphate oxidase activity
ET948_RS16800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ET948_RS16815	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ET948_RS16815	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ET948_RS16815	COG0506	proline dehydrogenase activity
ET948_RS16835	COG0840	transmembrane signaling receptor activity
ET948_RS16845	COG0513	Belongs to the DEAD box helicase family
ET948_RS16850	COG0583	DNA-binding transcription factor activity
ET948_RS16855	COG2910	NAD(P)H-binding
ET948_RS16860	COG3706	GGDEF domain
ET948_RS16865	COG4628	conserved protein (DUF2132)
ET948_RS16870	COG0095	Lipoate-protein ligase
ET948_RS16875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ET948_RS16885	COG3722	fumarate hydratase activity
ET948_RS16895	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET948_RS16895	COG2213	PTS system mannitol-specific
ET948_RS16900	COG0739	heme binding
ET948_RS16910	COG0564	pseudouridine synthase activity
ET948_RS16930	COG1869	D-ribose catabolic process
ET948_RS16935	COG1129	ABC transporter
ET948_RS16940	COG1172	Belongs to the binding-protein-dependent transport system permease family
ET948_RS16945	COG1879	ABC-type sugar transport system periplasmic component
ET948_RS16950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ET948_RS16955	COG1609	Transcriptional regulator
ET948_RS16960	COG0583	DNA-binding transcription factor activity
ET948_RS16965	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ET948_RS16970	COG3530	Putative quorum-sensing-regulated virulence factor
ET948_RS16980	COG1629	transport
ET948_RS16980	COG4771	TonB-dependent receptor
ET948_RS16990	COG1278	Cold shock
ET948_RS17000	COG0513	Belongs to the DEAD box helicase family
ET948_RS17005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ET948_RS17015	COG3724	N-succinylarginine dihydrolase activity
ET948_RS17035	COG2304	oxidoreductase activity
ET948_RS17055	COG0714	Associated with various cellular activities
ET948_RS17070	COG0366	Alpha amylase catalytic
ET948_RS17075	COG2195	Cleaves the N-terminal amino acid of tripeptides
ET948_RS17085	COG3604	Transcriptional regulator
ET948_RS17090	COG1017	nitric oxide dioxygenase activity
ET948_RS17090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ET948_RS17095	COG1278	Cold shock
ET948_RS17110	COG0745	RESPONSE REGULATOR receiver
ET948_RS17120	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ET948_RS17120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ET948_RS17125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ET948_RS17130	COG0516	GMP reductase activity
ET948_RS17145	COG5001	Diguanylate cyclase
ET948_RS17145	COG3300	MHYT domain
ET948_RS17150	COG2259	Doxx family
ET948_RS17160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ET948_RS17165	COG2197	response regulator
ET948_RS17170	COG0500	methyltransferase
ET948_RS17170	COG3615	Tellurite resistance protein tehB
ET948_RS17185	COG2200	EAL domain
ET948_RS17195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ET948_RS17205	COG0363	glucosamine-6-phosphate deaminase activity
ET948_RS17230	COG0513	Belongs to the DEAD box helicase family
ET948_RS17235	COG3314	Sporulation integral membrane protein YlbJ
ET948_RS17240	COG0659	secondary active sulfate transmembrane transporter activity
ET948_RS17250	COG0739	heme binding
ET948_RS17255	COG5001	Diguanylate cyclase
ET948_RS17265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ET948_RS17270	COG0179	Fumarylacetoacetate (FAA) hydrolase
ET948_RS17295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ET948_RS17300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ET948_RS17315	COG0840	transmembrane signaling receptor activity
ET948_RS17325	COG2200	EAL domain
ET948_RS17340	COG1620	l-lactate permease
ET948_RS17345	COG0583	DNA-binding transcription factor activity
ET948_RS17355	COG1067	ATP-dependent peptidase activity
ET948_RS17365	COG3123	guanosine phosphorylase activity
ET948_RS17370	COG1741	Belongs to the pirin family
ET948_RS17395	COG3706	GGDEF domain
ET948_RS17400	COG0784	Response regulator, receiver
ET948_RS17400	COG0835	chemotaxis
ET948_RS17405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ET948_RS17410	COG3047	cAMP biosynthetic process
ET948_RS17420	COG4989	oxidoreductase activity
ET948_RS17425	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ET948_RS17435	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ET948_RS17445	COG2814	Major facilitator Superfamily
ET948_RS17460	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET948_RS17465	COG4605	iron ion homeostasis
ET948_RS17470	COG4604	ABC transporter, ATP-binding protein
ET948_RS17480	COG3706	GGDEF domain
ET948_RS17495	COG4999	Histidine kinase
ET948_RS17495	COG3850	Histidine kinase
ET948_RS17495	COG3437	response regulator, receiver
ET948_RS17495	COG2205	protein histidine kinase activity
ET948_RS17500	COG2197	response regulator
ET948_RS17525	COG2113	Glycine betaine
ET948_RS17530	COG4176	ABC-type proline glycine betaine transport system permease component
ET948_RS17535	COG4175	Glycine betaine
ET948_RS17545	COG1166	arginine decarboxylase activity
ET948_RS17550	COG0010	Belongs to the arginase family
ET948_RS17555	COG1686	Belongs to the peptidase S11 family
ET948_RS17580	COG3188	usher protein