locus-tag	class	description
BA953_RS00010	COG0840	transmembrane signaling receptor activity
BA953_RS00015	COG1328	CTP reductase activity
BA953_RS00020	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BA953_RS00065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA953_RS00070	COG0745	RESPONSE REGULATOR receiver
BA953_RS00075	COG2205	protein histidine kinase activity
BA953_RS00090	COG0811	peptide transport
BA953_RS00095	COG0811	peptide transport
BA953_RS00100	COG0848	biopolymer transport protein
BA953_RS00120	COG3290	protein histidine kinase activity
BA953_RS00125	COG4565	transcriptional regulatory protein
BA953_RS00145	COG2199	diguanylate cyclase activity
BA953_RS00150	COG0840	transmembrane signaling receptor activity
BA953_RS00155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BA953_RS00165	COG2116	formate transmembrane transporter activity
BA953_RS00185	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BA953_RS00205	COG0583	DNA-binding transcription factor activity
BA953_RS00215	COG0745	RESPONSE REGULATOR receiver
BA953_RS00225	COG3713	MltA-interacting MipA family protein
BA953_RS00230	COG2990	Protein conserved in bacteria
BA953_RS00235	COG2186	Transcriptional regulator
BA953_RS00245	COG1288	antiporter activity
BA953_RS00255	COG2814	Major facilitator Superfamily
BA953_RS00265	COG3835	regulator
BA953_RS00270	COG1929	Belongs to the glycerate kinase type-1 family
BA953_RS00275	COG2977	Belongs to the P-Pant transferase superfamily
BA953_RS00280	COG1120	ATPase activity
BA953_RS00285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA953_RS00295	COG4615	Cyclic peptide transporter
BA953_RS00315	COG4774	siderophore transport
BA953_RS00350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BA953_RS00360	COG0297	glycogen (starch) synthase activity
BA953_RS00390	COG0438	transferase activity, transferring glycosyl groups
BA953_RS00395	COG0438	transferase activity, transferring glycosyl groups
BA953_RS00405	COG2204	response regulator
BA953_RS00450	COG0534	Mate efflux family protein
BA953_RS00455	COG0307	riboflavin synthase, alpha
BA953_RS00465	COG3001	Fructosamine kinase
BA953_RS00475	COG0791	NLP P60 protein
BA953_RS00480	COG0840	transmembrane signaling receptor activity
BA953_RS00490	COG3148	PFAM DTW domain containing protein
BA953_RS00495	COG1940	carbohydrate kinase activity
BA953_RS00510	COG0303	'Molybdopterin
BA953_RS00515	COG0746	molybdenum cofactor guanylyltransferase activity
BA953_RS00520	COG3842	ATPase activity
BA953_RS00525	COG4662	Binding-protein-dependent transport system inner membrane component
BA953_RS00540	COG3852	Histidine kinase
BA953_RS00555	COG1595	DNA-templated transcription, initiation
BA953_RS00565	COG0488	(ABC) transporter
BA953_RS00580	COG1028	Short-chain dehydrogenase reductase Sdr
BA953_RS00590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA953_RS00595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA953_RS00600	COG3710	Transcriptional regulator
BA953_RS00605	COG0069	glutamate synthase activity
BA953_RS00625	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BA953_RS00630	COG0583	DNA-binding transcription factor activity
BA953_RS00660	COG3038	cytochrome b561
BA953_RS00665	COG0840	transmembrane signaling receptor activity
BA953_RS00670	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BA953_RS00700	COG0243	molybdopterin cofactor binding
BA953_RS00700	COG3383	formate dehydrogenase (NAD+) activity
BA953_RS00705	COG0437	4 iron, 4 sulfur cluster binding
BA953_RS00720	COG0004	ammonium transporteR
BA953_RS00725	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BA953_RS00730	COG2199	diguanylate cyclase activity
BA953_RS00740	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BA953_RS00745	COG1177	transmembrane transport
BA953_RS00755	COG3842	ATPase activity
BA953_RS00875	COG0589	response to stress
BA953_RS00880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BA953_RS00895	COG2217	Heavy metal translocating P-type atpase
BA953_RS00905	COG2010	Cytochrome c
BA953_RS00920	COG3278	Belongs to the heme-copper respiratory oxidase family
BA953_RS01025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BA953_RS01025	COG0596	Alpha beta hydrolase
BA953_RS01025	COG2226	methyltransferase
BA953_RS01070	COG1132	(ABC) transporter
BA953_RS01095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA953_RS01100	COG2801	Transposase and inactivated derivatives
BA953_RS01105	COG0583	DNA-binding transcription factor activity
BA953_RS01120	COG1942	4-Oxalocrotonate Tautomerase
BA953_RS01135	COG3135	benzoate transporter
BA953_RS01140	COG1396	sequence-specific DNA binding
BA953_RS01150	COG1858	cytochrome C peroxidase
BA953_RS01275	COG0840	transmembrane signaling receptor activity
BA953_RS01435	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BA953_RS01455	COG0789	Transcriptional regulator
BA953_RS01515	COG1067	ATP-dependent peptidase activity
BA953_RS01520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BA953_RS01535	COG0488	(ABC) transporter
BA953_RS01555	COG0167	dihydroorotate dehydrogenase activity
BA953_RS01570	COG0308	aminopeptidase N
BA953_RS01585	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BA953_RS01590	COG1956	GAF domain-containing protein
BA953_RS01595	COG1132	(ABC) transporter
BA953_RS01600	COG2995	paraquat-inducible protein a
BA953_RS01610	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BA953_RS01610	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BA953_RS01635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BA953_RS01650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA953_RS01655	COG4597	amino acid ABC transporter
BA953_RS01660	COG0765	amino acid transport
BA953_RS01665	COG1126	abc transporter atp-binding protein
BA953_RS01670	COG0670	Belongs to the BI1 family
BA953_RS01675	COG2920	part of a sulfur-relay system
BA953_RS01680	COG1254	Belongs to the acylphosphatase family
BA953_RS01690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BA953_RS01720	COG0602	queuosine metabolic process
BA953_RS01725	COG0561	phosphatase activity
BA953_RS01745	COG2828	Protein conserved in bacteria
BA953_RS01755	COG0372	Belongs to the citrate synthase family
BA953_RS01760	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BA953_RS01875	COG0515	serine threonine protein kinase
BA953_RS01905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA953_RS01920	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BA953_RS01935	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BA953_RS01940	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA953_RS01940	COG0596	Alpha beta hydrolase
BA953_RS01945	COG3063	Type IV pilus biogenesis stability protein PilW
BA953_RS01960	COG1451	nucleotide metabolic process
BA953_RS01970	COG5002	protein histidine kinase activity
BA953_RS01970	COG0784	Response regulator, receiver
BA953_RS01980	COG1119	ATPase activity
BA953_RS01990	COG2814	Major facilitator Superfamily
BA953_RS02015	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BA953_RS02020	COG4139	cobalamin transport
BA953_RS02035	COG0406	alpha-ribazole phosphatase activity
BA953_RS02045	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BA953_RS02050	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BA953_RS02055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BA953_RS02060	COG0702	epimerase
BA953_RS02065	COG1823	symporter activity
BA953_RS02070	COG2925	Exonuclease
BA953_RS02075	COG1380	Effector of murein hydrolase LrgA
BA953_RS02080	COG1346	cytolysis
BA953_RS02085	COG0295	cytidine deaminase activity
BA953_RS02100	COG0500	methyltransferase
BA953_RS02120	COG4326	sporulation control protein
BA953_RS02125	COG2188	Transcriptional regulator
BA953_RS02130	COG1228	amidohydrolase
BA953_RS02135	COG0010	Belongs to the arginase family
BA953_RS02145	COG2986	histidine ammonia-lyase
BA953_RS02160	COG0247	lactate metabolic process
BA953_RS02160	COG0277	FAD linked oxidase domain protein
BA953_RS02175	COG2885	chlorophyll binding
BA953_RS02190	COG0625	glutathione transferase activity
BA953_RS02200	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BA953_RS02210	COG2195	Cleaves the N-terminal amino acid of tripeptides
BA953_RS02230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BA953_RS02250	COG0456	acetyltransferase
BA953_RS02275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA953_RS02280	COG0454	-acetyltransferase
BA953_RS02335	COG3122	Protein conserved in bacteria
BA953_RS02375	COG2824	Alkylphosphonate utilization operon protein PhnA
BA953_RS02400	COG0730	response to heat
BA953_RS02420	COG0456	acetyltransferase
BA953_RS02435	COG4628	conserved protein (DUF2132)
BA953_RS02460	COG0546	phosphoglycolate phosphatase activity
BA953_RS02470	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BA953_RS02515	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BA953_RS02530	COG2801	Transposase and inactivated derivatives
BA953_RS02535	COG2801	Transposase and inactivated derivatives
BA953_RS02545	COG2026	Addiction module toxin, RelE StbE family
BA953_RS02630	COG2962	Rard protein
BA953_RS02635	COG0531	amino acid
BA953_RS02645	COG0783	Belongs to the Dps family
BA953_RS02650	COG4667	esterase of the alpha-beta hydrolase superfamily
BA953_RS02685	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BA953_RS02700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA953_RS02705	COG3108	Peptidase M15
BA953_RS02710	COG2989	Protein conserved in bacteria
BA953_RS02735	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BA953_RS02760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA953_RS02775	COG3106	COG3106 Predicted ATPase
BA953_RS02795	COG2205	protein histidine kinase activity
BA953_RS02795	COG0784	Response regulator, receiver
BA953_RS02805	COG0494	nUDIX hydrolase
BA953_RS02810	COG0814	amino acid
BA953_RS02815	COG1760	l-serine dehydratase
BA953_RS02825	COG0814	amino acid
BA953_RS02835	COG0840	transmembrane signaling receptor activity
BA953_RS02840	COG0017	Asparaginyl-tRNA synthetase
BA953_RS02850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA953_RS02860	COG3437	response regulator, receiver
BA953_RS02860	COG2770	Histidine kinase
BA953_RS02865	COG1448	Aminotransferase
BA953_RS02880	COG1643	Atp-dependent helicase
BA953_RS02885	COG0281	malic enzyme
BA953_RS02895	COG2949	membrane
BA953_RS02905	COG0612	Peptidase, M16
BA953_RS02920	COG2175	clavaminate synthase activity
BA953_RS02935	COG0492	ferredoxin-NADP+ reductase activity
BA953_RS02940	COG4988	ABC transporter
BA953_RS02945	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BA953_RS02950	COG2814	Major facilitator Superfamily
BA953_RS02960	COG0384	phenazine biosynthesis protein PhzF
BA953_RS02965	COG1187	pseudouridine synthase activity
BA953_RS02980	COG0009	L-threonylcarbamoyladenylate synthase
BA953_RS02985	COG0613	PHP domain protein
BA953_RS02995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BA953_RS03000	COG0512	Glutamine amidotransferase of anthranilate synthase
BA953_RS03005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BA953_RS03010	COG0134	indole-3-glycerol-phosphate synthase activity
BA953_RS03010	COG0135	phosphoribosylanthranilate isomerase activity
BA953_RS03020	COG0159	tryptophan synthase activity
BA953_RS03025	COG1301	dicarboxylic acid transport
BA953_RS03090	COG0443	Heat shock 70 kDa protein
BA953_RS03100	COG1858	cytochrome C peroxidase
BA953_RS03150	COG2801	Transposase and inactivated derivatives
BA953_RS03160	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BA953_RS03165	COG0840	transmembrane signaling receptor activity
BA953_RS03185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BA953_RS03195	COG2207	Transcriptional regulator
BA953_RS03200	COG0583	DNA-binding transcription factor activity
BA953_RS03215	COG0673	inositol 2-dehydrogenase activity
BA953_RS03225	COG0583	DNA-binding transcription factor activity
BA953_RS03240	COG1846	Transcriptional regulator
BA953_RS03245	COG1764	response to oxidative stress
BA953_RS03250	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BA953_RS03280	COG1032	radical SAM domain protein
BA953_RS03290	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BA953_RS03300	COG4191	Histidine kinase
BA953_RS03300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA953_RS03315	COG3070	regulator of competence-specific genes
BA953_RS03325	COG2431	L-lysine efflux transmembrane transporter activity
BA953_RS03335	COG0076	glutamate decarboxylase activity
BA953_RS03340	COG1737	Transcriptional regulator
BA953_RS03350	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BA953_RS03360	COG4160	amino acid transport
BA953_RS03385	COG1882	Formate acetyltransferase
BA953_RS03400	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BA953_RS03410	COG3013	Belongs to the UPF0304 family
BA953_RS03415	COG3713	MltA-interacting MipA family protein
BA953_RS03420	COG2766	serine protein kinase
BA953_RS03425	COG2718	Belongs to the UPF0229 family
BA953_RS03430	COG2719	SpoVR family
BA953_RS03435	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BA953_RS03440	COG2835	tetraacyldisaccharide 4'-kinase activity
BA953_RS03450	COG1132	(ABC) transporter
BA953_RS03455	COG0658	competence protein
BA953_RS03455	COG2333	competence protein COMEC
BA953_RS03465	COG4591	ABC-type transport system involved in lipoprotein release permease component
BA953_RS03470	COG1136	(ABC) transporter
BA953_RS03475	COG4591	ABC-type transport system involved in lipoprotein release permease component
BA953_RS03485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BA953_RS03505	COG1252	NADH dehydrogenase
BA953_RS03535	COG0537	adenosine 5'-monophosphoramidase activity
BA953_RS03550	COG2186	Transcriptional regulator
BA953_RS03555	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BA953_RS03565	COG1674	ftsk spoiiie
BA953_RS03575	COG0686	Belongs to the AlaDH PNT family
BA953_RS03580	COG3092	negative regulation of chromosome organization
BA953_RS03585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BA953_RS03590	COG0857	belongs to the CobB CobQ family
BA953_RS03590	COG0280	phosphate acetyltransferase
BA953_RS03595	COG3706	GGDEF domain
BA953_RS03600	COG0435	Glutathione S-transferase
BA953_RS03610	COG0444	Belongs to the ABC transporter superfamily
BA953_RS03615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA953_RS03620	COG0601	transmembrane transport
BA953_RS03635	COG2067	long-chain fatty acid transport protein
BA953_RS03640	COG3706	GGDEF domain
BA953_RS03665	COG1404	Belongs to the peptidase S8 family
BA953_RS03670	COG0840	transmembrane signaling receptor activity
BA953_RS03680	COG0330	HflC and HflK could
BA953_RS03700	COG1136	(ABC) transporter
BA953_RS03700	COG0577	efflux transmembrane transporter activity
BA953_RS03710	COG0577	efflux transmembrane transporter activity
BA953_RS03720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA953_RS03730	COG3227	Zinc metalloprotease (Elastase)
BA953_RS03740	COG1770	oligopeptidase
BA953_RS03745	COG3397	chitin binding
BA953_RS03765	COG3876	Protein conserved in bacteria
BA953_RS03770	COG1472	Belongs to the glycosyl hydrolase 3 family
BA953_RS03790	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BA953_RS03795	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BA953_RS03800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA953_RS03815	COG2855	membrane
BA953_RS03835	COG0730	response to heat
BA953_RS03840	COG0280	phosphate acetyltransferase
BA953_RS03845	COG1414	Transcriptional regulator
BA953_RS03890	COG3706	GGDEF domain
BA953_RS03905	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BA953_RS03910	COG1946	Acyl-CoA thioesterase
BA953_RS03925	COG1522	sequence-specific DNA binding
BA953_RS03950	COG0477	Major facilitator Superfamily
BA953_RS03955	COG2855	membrane
BA953_RS03975	COG0596	Alpha beta hydrolase
BA953_RS03980	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BA953_RS03985	COG1169	isochorismate synthase
BA953_RS03990	COG0436	Aminotransferase
BA953_RS03995	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BA953_RS04005	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BA953_RS04010	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BA953_RS04025	COG0513	Belongs to the DEAD box helicase family
BA953_RS04030	COG0616	signal peptide processing
BA953_RS04035	COG1028	Short-chain dehydrogenase reductase Sdr
BA953_RS04050	COG0587	DNA-directed DNA polymerase activity
BA953_RS04055	COG0784	Response regulator, receiver
BA953_RS04055	COG0835	chemotaxis
BA953_RS04060	COG1940	carbohydrate kinase activity
BA953_RS04065	COG0469	pyruvate kinase activity
BA953_RS04070	COG4667	esterase of the alpha-beta hydrolase superfamily
BA953_RS04080	COG0733	neurotransmitter:sodium symporter activity
BA953_RS04090	COG1263	PTS System
BA953_RS04090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA953_RS04095	COG0084	hydrolase, TatD family'
BA953_RS04100	COG0470	DNA polymerase III
BA953_RS04105	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BA953_RS04110	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BA953_RS04115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BA953_RS04140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA953_RS04150	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BA953_RS04155	COG1399	metal-binding, possibly nucleic acid-binding protein
BA953_RS04160	COG0424	maF-like protein
BA953_RS04165	COG0564	pseudouridine synthase activity
BA953_RS04170	COG1530	ribonuclease E activity
BA953_RS04175	COG0659	secondary active sulfate transmembrane transporter activity
BA953_RS04180	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BA953_RS04185	COG0318	PFAM AMP-dependent synthetase and ligase
BA953_RS04190	COG2267	carboxylic ester hydrolase activity
BA953_RS04205	COG1214	PFAM Peptidase M22, glycoprotease
BA953_RS04210	COG1199	ATP-dependent helicase activity
BA953_RS04220	COG0788	formyltetrahydrofolate deformylase activity
BA953_RS04225	COG0446	pyridine nucleotide-disulphide oxidoreductase
BA953_RS04225	COG1902	pentaerythritol trinitrate reductase activity
BA953_RS04230	COG0616	signal peptide processing
BA953_RS04235	COG0252	asparaginase activity
BA953_RS04245	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BA953_RS04250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BA953_RS04270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BA953_RS04275	COG3706	GGDEF domain
BA953_RS04285	COG4120	Belongs to the binding-protein-dependent transport system permease family
BA953_RS04320	COG0284	orotidine-5'-phosphate decarboxylase activity
BA953_RS04325	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BA953_RS04330	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BA953_RS04340	COG0539	negative regulation of cytoplasmic translation
BA953_RS04350	COG1555	photosystem II stabilization
BA953_RS04355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA953_RS04360	COG0776	regulation of translation
BA953_RS04365	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BA953_RS04390	COG2204	response regulator
BA953_RS04400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BA953_RS04405	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BA953_RS04410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BA953_RS04415	COG3842	ATPase activity
BA953_RS04425	COG1175	transmembrane transport
BA953_RS04430	COG1653	transport
BA953_RS04465	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BA953_RS04480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BA953_RS04485	COG2832	Protein of unknown function (DUF454)
BA953_RS04490	COG0745	RESPONSE REGULATOR receiver
BA953_RS04495	COG0583	DNA-binding transcription factor activity
BA953_RS04500	COG0778	Nitroreductase
BA953_RS04510	COG0183	Belongs to the thiolase family
BA953_RS04525	COG2067	long-chain fatty acid transport protein
BA953_RS04530	COG2067	long-chain fatty acid transport protein
BA953_RS04535	COG2853	Lipoprotein
BA953_RS04545	COG4235	cytochrome complex assembly
BA953_RS04545	COG3088	subunit of a heme lyase
BA953_RS04550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA953_RS04555	COG1138	Cytochrome C-type biogenesis protein
BA953_RS04565	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BA953_RS04570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BA953_RS04575	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BA953_RS04580	COG4133	protoheme IX ABC transporter activity
BA953_RS04590	COG0835	chemotaxis
BA953_RS04600	COG1192	Involved in chromosome partitioning
BA953_RS04605	COG2201	protein-glutamate methylesterase activity
BA953_RS04610	COG0784	Response regulator, receiver
BA953_RS04610	COG2198	Histidine kinase
BA953_RS04610	COG0643	Histidine kinase
BA953_RS04615	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BA953_RS04645	COG2062	phosphohistidine phosphatase, SixA
BA953_RS04655	COG3102	Protein conserved in bacteria
BA953_RS04675	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BA953_RS04680	COG1918	ferrous iron import across plasma membrane
BA953_RS04685	COG4977	sequence-specific DNA binding
BA953_RS04690	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BA953_RS04695	COG1121	(ABC) transporter
BA953_RS04700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BA953_RS04705	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BA953_RS04710	COG1286	toxin biosynthetic process
BA953_RS04715	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BA953_RS04720	COG0285	dihydrofolate synthase activity
BA953_RS04725	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BA953_RS04730	COG0101	tRNA pseudouridine synthase activity
BA953_RS04740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BA953_RS04745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BA953_RS04750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BA953_RS04780	COG3101	peptidyl-lysine hydroxylation
BA953_RS04785	COG2860	membrane
BA953_RS04795	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BA953_RS04800	COG2890	protein-(glutamine-N5) methyltransferase activity
BA953_RS04815	COG1684	flagellar biosynthetic protein fliR
BA953_RS04820	COG1987	bacterial-type flagellum assembly
BA953_RS04870	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BA953_RS04880	COG1677	Flagellar hook-basal body complex protein FliE
BA953_RS04900	COG1516	flagellar protein fliS
BA953_RS04910	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BA953_RS04920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BA953_RS04935	COG2837	iron assimilation
BA953_RS04945	COG4235	cytochrome complex assembly
BA953_RS04945	COG3088	subunit of a heme lyase
BA953_RS04950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA953_RS04955	COG1138	Cytochrome C-type biogenesis protein
BA953_RS04960	COG3301	Polysulphide reductase, NrfD
BA953_RS04965	COG0437	4 iron, 4 sulfur cluster binding
BA953_RS04970	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BA953_RS04975	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BA953_RS05000	COG1393	Belongs to the ArsC family
BA953_RS05005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BA953_RS05020	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BA953_RS05030	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BA953_RS05030	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BA953_RS05045	COG1611	Belongs to the LOG family
BA953_RS05050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BA953_RS05060	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BA953_RS05075	COG0583	DNA-binding transcription factor activity
BA953_RS05080	COG0301	tRNA thio-modification
BA953_RS05080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA953_RS05090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BA953_RS05095	COG1722	exodeoxyribonuclease VII activity
BA953_RS05100	COG0142	geranyltranstransferase activity
BA953_RS05110	COG0564	pseudouridine synthase activity
BA953_RS05115	COG3098	single-species biofilm formation
BA953_RS05145	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA953_RS05150	COG0567	Dehydrogenase, E1 component
BA953_RS05155	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BA953_RS05160	COG1053	succinate dehydrogenase
BA953_RS05165	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BA953_RS05180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BA953_RS05190	COG0033	Phosphoglucomutase
BA953_RS05195	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BA953_RS05200	COG0596	Alpha beta hydrolase
BA953_RS05225	COG0167	dihydroorotate dehydrogenase activity
BA953_RS05240	COG1263	PTS System
BA953_RS05240	COG2190	(PTS) system
BA953_RS05240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA953_RS05245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BA953_RS05250	COG1940	carbohydrate kinase activity
BA953_RS05250	COG1846	Transcriptional regulator
BA953_RS05255	COG4651	solute:proton antiporter activity
BA953_RS05255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BA953_RS05260	COG0367	asparagine synthase
BA953_RS05265	COG3104	oligopeptide transport
BA953_RS05290	COG2840	Smr protein MutS2
BA953_RS05295	COG1187	pseudouridine synthase activity
BA953_RS05300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BA953_RS05305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BA953_RS05310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BA953_RS05335	COG0047	phosphoribosylformylglycinamidine synthase activity
BA953_RS05335	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BA953_RS05340	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BA953_RS05350	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BA953_RS05370	COG4970	Tfp pilus assembly protein FimT
BA953_RS05385	COG0443	Heat shock 70 kDa protein
BA953_RS05390	COG1301	dicarboxylic acid transport
BA953_RS05395	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BA953_RS05400	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BA953_RS05405	COG0497	DNA recombination
BA953_RS05410	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BA953_RS05415	COG2914	Belongs to the UPF0125 (RnfH) family
BA953_RS05420	COG2867	negative regulation of translational initiation
BA953_RS05435	COG0582	viral genome integration into host DNA
BA953_RS05440	COG1715	Restriction endonuclease
BA953_RS05455	COG0732	type I restriction modification DNA specificity domain
BA953_RS05460	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BA953_RS05495	COG1396	sequence-specific DNA binding
BA953_RS05500	COG3550	peptidyl-serine autophosphorylation
BA953_RS05510	COG2207	Transcriptional regulator
BA953_RS05515	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BA953_RS05570	COG4977	sequence-specific DNA binding
BA953_RS05570	COG1917	Cupin 2, conserved barrel domain protein
BA953_RS05585	COG0668	transmembrane transport
BA953_RS05590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BA953_RS05615	COG0204	Acyl-transferase
BA953_RS05620	COG0784	Response regulator, receiver
BA953_RS05620	COG0835	chemotaxis
BA953_RS05625	COG2873	o-acetylhomoserine
BA953_RS05645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA953_RS05650	COG1115	amino acid carrier protein
BA953_RS05655	COG1584	GPR1 FUN34 yaaH family protein
BA953_RS05670	COG0517	IMP dehydrogenase activity
BA953_RS05670	COG0516	GMP reductase activity
BA953_RS05685	COG2203	Gaf domain
BA953_RS05685	COG2199	diguanylate cyclase activity
BA953_RS05695	COG1160	GTP binding
BA953_RS05700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BA953_RS05705	COG2976	Protein conserved in bacteria
BA953_RS05710	COG0124	histidyl-tRNA synthetase
BA953_RS05715	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BA953_RS05720	COG1426	Protein conserved in bacteria
BA953_RS05730	COG2166	iron-sulfur cluster assembly
BA953_RS05735	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BA953_RS05740	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BA953_RS05760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BA953_RS05765	COG1074	ATP-dependent DNA helicase activity
BA953_RS05770	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BA953_RS05790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA953_RS05795	COG1309	transcriptional regulator
BA953_RS05800	COG3141	response to X-ray
BA953_RS05815	COG0704	Plays a role in the regulation of phosphate uptake
BA953_RS05820	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BA953_RS05825	COG0581	inorganic phosphate transmembrane transporter activity
BA953_RS05830	COG0573	inorganic phosphate transmembrane transporter activity
BA953_RS05835	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BA953_RS05840	COG0248	Ppx GppA phosphatase
BA953_RS05850	COG5002	protein histidine kinase activity
BA953_RS05855	COG0745	RESPONSE REGULATOR receiver
BA953_RS05865	COG0826	peptidase U32
BA953_RS05870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BA953_RS05890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BA953_RS05895	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BA953_RS05900	COG1862	Preprotein translocase
BA953_RS05910	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BA953_RS05915	COG0517	IMP dehydrogenase activity
BA953_RS05925	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BA953_RS05935	COG0450	alkyl hydroperoxide reductase
BA953_RS05940	COG2171	N-acyltransferase activity
BA953_RS05950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BA953_RS05960	COG2207	Transcriptional regulator
BA953_RS05965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BA953_RS05965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA953_RS05965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BA953_RS05980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA953_RS06000	COG1085	galactose-1-phosphate uridylyltransferase
BA953_RS06005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BA953_RS06010	COG1609	Transcriptional regulator
BA953_RS06015	COG3250	beta-galactosidase activity
BA953_RS06020	COG2731	YhcH YjgK YiaL family protein
BA953_RS06025	COG0531	amino acid
BA953_RS06030	COG1309	transcriptional regulator
BA953_RS06045	COG3408	Glycogen debranching enzyme
BA953_RS06045	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BA953_RS06055	COG2211	Major facilitator Superfamily
BA953_RS06060	COG1486	melibiose metabolic process
BA953_RS06065	COG2169	Transcriptional regulator
BA953_RS06130	COG4964	Belongs to the GSP D family
BA953_RS06165	COG2169	Transcriptional regulator
BA953_RS06170	COG1022	Amp-dependent synthetase and ligase
BA953_RS06175	COG0583	DNA-binding transcription factor activity
BA953_RS06185	COG0583	DNA-binding transcription factor activity
BA953_RS06190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BA953_RS06200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BA953_RS06205	COG2975	iron-sulfur cluster assembly
BA953_RS06210	COG0633	Ferredoxin
BA953_RS06215	COG0443	Heat shock 70 kDa protein
BA953_RS06230	COG0822	iron-sulfur transferase activity
BA953_RS06235	COG1104	cysteine desulfurase activity
BA953_RS06250	COG0483	inositol monophosphate 1-phosphatase activity
BA953_RS06290	COG0542	response to heat
BA953_RS06295	COG1496	oxidoreductase activity
BA953_RS06300	COG0564	pseudouridine synthase activity
BA953_RS06305	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BA953_RS06310	COG0741	lytic transglycosylase activity
BA953_RS06315	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BA953_RS06320	COG1605	Chorismate mutase
BA953_RS06320	COG0077	Prephenate dehydratase
BA953_RS06325	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BA953_RS06330	COG5001	Diguanylate cyclase
BA953_RS06335	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BA953_RS06340	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
BA953_RS06345	COG0741	lytic transglycosylase activity
BA953_RS06350	COG0488	(ABC) transporter
BA953_RS06360	COG0739	heme binding
BA953_RS06365	COG1605	Chorismate mutase
BA953_RS06365	COG0287	Prephenate dehydrogenase
BA953_RS06370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BA953_RS06375	COG3275	phosphorelay sensor kinase activity
BA953_RS06380	COG3279	Response regulator of the LytR AlgR family
BA953_RS06390	COG1737	Transcriptional regulator
BA953_RS06410	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BA953_RS06420	COG1966	Carbon starvation protein
BA953_RS06425	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BA953_RS06430	COG1047	Peptidyl-prolyl cis-trans
BA953_RS06445	COG0196	riboflavin kinase activity
BA953_RS06450	COG0728	peptidoglycan biosynthetic process
BA953_RS06455	COG0268	Binds directly to 16S ribosomal RNA
BA953_RS06460	COG0640	Transcriptional regulator
BA953_RS06465	COG0583	DNA-binding transcription factor activity
BA953_RS06475	COG1283	sodium-dependent phosphate transmembrane transporter activity
BA953_RS06480	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BA953_RS06490	COG0730	response to heat
BA953_RS06505	COG3066	DNA modification
BA953_RS06515	COG0667	Aldo Keto reductase
BA953_RS06525	COG2204	response regulator
BA953_RS06535	COG1846	Transcriptional regulator
BA953_RS06550	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BA953_RS06560	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BA953_RS06565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA953_RS06570	COG2860	membrane
BA953_RS06575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BA953_RS06580	COG0083	homoserine kinase activity
BA953_RS06595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BA953_RS06605	COG0745	RESPONSE REGULATOR receiver
BA953_RS06610	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BA953_RS06610	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BA953_RS06615	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BA953_RS06625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BA953_RS06630	COG3025	triphosphatase activity
BA953_RS06635	COG1392	Phosphate transport regulator
BA953_RS06640	COG0306	phosphate transporter
BA953_RS06645	COG4991	sh3 domain protein
BA953_RS06655	COG3409	Peptidoglycan-binding domain 1 protein
BA953_RS06655	COG3267	Type II secretory pathway component ExeA
BA953_RS06665	COG0148	phosphopyruvate hydratase activity
BA953_RS06680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BA953_RS06685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BA953_RS06690	COG3437	response regulator, receiver
BA953_RS06690	COG3850	Histidine kinase
BA953_RS06690	COG2205	protein histidine kinase activity
BA953_RS06690	COG4999	Histidine kinase
BA953_RS06695	COG0736	holo-[acyl-carrier-protein] synthase activity
BA953_RS06700	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BA953_RS06705	COG1381	Involved in DNA repair and RecF pathway recombination
BA953_RS06710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BA953_RS06715	COG0571	ribonuclease III activity
BA953_RS06725	COG0481	GTPase activity
BA953_RS06730	COG3086	response to oxidative stress
BA953_RS06735	COG3026	antisigma factor binding
BA953_RS06745	COG1595	DNA-templated transcription, initiation
BA953_RS06750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BA953_RS06780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BA953_RS06785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BA953_RS06790	COG3079	Belongs to the UPF0149 family
BA953_RS06795	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BA953_RS06805	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BA953_RS06815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BA953_RS06820	COG2271	Major facilitator Superfamily
BA953_RS06825	COG0584	glycerophosphoryl diester phosphodiesterase
BA953_RS06830	COG0440	acetolactate synthase activity
BA953_RS06835	COG0028	Belongs to the TPP enzyme family
BA953_RS06840	COG1022	Amp-dependent synthetase and ligase
BA953_RS06845	COG0583	DNA-binding transcription factor activity
BA953_RS06865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BA953_RS06870	COG0473	3-isopropylmalate dehydrogenase activity
BA953_RS06950	COG1854	S-ribosylhomocysteine lyase activity
BA953_RS06960	COG2918	glutathione biosynthetic process
BA953_RS06965	COG0612	Peptidase, M16
BA953_RS06970	COG1238	metal cluster binding
BA953_RS06980	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BA953_RS06985	COG5016	pyruvate
BA953_RS06985	COG0511	ligase activity, forming carbon-carbon bonds
BA953_RS06990	COG3630	sodium ion export across plasma membrane
BA953_RS07040	COG0527	aspartate kinase activity
BA953_RS07050	COG2137	regulation of response to DNA damage stimulus
BA953_RS07055	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BA953_RS07060	COG1546	Belongs to the CinA family
BA953_RS07065	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BA953_RS07070	COG0795	lipopolysaccharide-transporting ATPase activity
BA953_RS07075	COG0795	lipopolysaccharide-transporting ATPase activity
BA953_RS07085	COG2927	DNA polymerase III (CHI subunit)
BA953_RS07090	COG0525	valine-tRNA ligase activity
BA953_RS07100	COG4269	membrane
BA953_RS07110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BA953_RS07115	COG0564	pseudouridine synthase activity
BA953_RS07125	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BA953_RS07130	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BA953_RS07145	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BA953_RS07150	COG0251	oxidation-reduction process
BA953_RS07160	COG0039	L-malate dehydrogenase activity
BA953_RS07165	COG1438	arginine binding
BA953_RS07170	COG2358	TRAP transporter, solute receptor (TAXI family
BA953_RS07180	COG0589	response to stress
BA953_RS07200	COG2235	arginine
BA953_RS07205	COG0204	Acyl-transferase
BA953_RS07215	COG5007	Belongs to the BolA IbaG family
BA953_RS07225	COG2854	intermembrane phospholipid transfer
BA953_RS07230	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BA953_RS07235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BA953_RS07240	COG1127	ABC transporter
BA953_RS07250	COG0517	IMP dehydrogenase activity
BA953_RS07250	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BA953_RS07255	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BA953_RS07265	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BA953_RS07270	COG1137	ATPase activity
BA953_RS07280	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BA953_RS07285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA953_RS07290	COG1660	Displays ATPase and GTPase activities
BA953_RS07295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA953_RS07300	COG2239	Acts as a magnesium transporter
BA953_RS07305	COG1410	methionine synthase
BA953_RS07305	COG0646	methionine synthase
BA953_RS07360	COG0175	sulfate reduction
BA953_RS07365	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BA953_RS07370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BA953_RS07400	COG3437	response regulator, receiver
BA953_RS07405	COG2205	protein histidine kinase activity
BA953_RS07405	COG0784	Response regulator, receiver
BA953_RS07405	COG5002	protein histidine kinase activity
BA953_RS07410	COG0735	belongs to the Fur family
BA953_RS07420	COG0529	Catalyzes the synthesis of activated sulfate
BA953_RS07425	COG0471	metal ion transport
BA953_RS07425	COG3273	potassium ion transport
BA953_RS07440	COG1648	precorrin-2 dehydrogenase activity
BA953_RS07440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BA953_RS07445	COG0737	Belongs to the 5'-nucleotidase family
BA953_RS07455	COG2153	protein acetylation
BA953_RS07470	COG0545	Peptidyl-prolyl cis-trans isomerase
BA953_RS07480	COG0203	ribosomal protein L17
BA953_RS07485	COG0202	RNA polymerase activity
BA953_RS07495	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BA953_RS07500	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BA953_RS07505	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BA953_RS07510	COG0201	protein transport
BA953_RS07515	COG0200	Binds to the 23S rRNA
BA953_RS07520	COG1841	ribosomal large subunit assembly
BA953_RS07535	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BA953_RS07550	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BA953_RS07565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BA953_RS07580	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BA953_RS07585	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BA953_RS07590	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BA953_RS07605	COG0088	Forms part of the polypeptide exit tunnel
BA953_RS07610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BA953_RS07615	COG0051	transcription antitermination factor activity, RNA binding
BA953_RS07620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BA953_RS07625	COG0557	exoribonuclease II activity
BA953_RS07630	COG0402	S-adenosylhomocysteine deaminase activity
BA953_RS07635	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BA953_RS07640	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BA953_RS07650	COG1047	Peptidyl-prolyl cis-trans
BA953_RS07665	COG2249	NAD(P)H dehydrogenase (quinone) activity
BA953_RS07670	COG0488	(ABC) transporter
BA953_RS07680	COG0429	hydrolase of the alpha beta-hydrolase fold
BA953_RS07690	COG3954	Phosphoribulokinase
BA953_RS07695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BA953_RS07705	COG1012	belongs to the aldehyde dehydrogenase family
BA953_RS07715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BA953_RS07740	COG1027	Aspartate ammonia-lyase
BA953_RS07745	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BA953_RS07750	COG1288	antiporter activity
BA953_RS07765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BA953_RS07770	COG0540	Belongs to the ATCase OTCase family
BA953_RS07775	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BA953_RS07780	COG1438	arginine binding
BA953_RS07785	COG4232	protein-disulfide reductase activity
BA953_RS07795	COG2095	MarC family integral membrane protein
BA953_RS07805	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA953_RS07815	COG0784	Response regulator, receiver
BA953_RS07815	COG2205	protein histidine kinase activity
BA953_RS07820	COG2814	Major facilitator Superfamily
BA953_RS07835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BA953_RS07840	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BA953_RS07845	COG0511	ligase activity, forming carbon-carbon bonds
BA953_RS07850	COG0439	Biotin carboxylase
BA953_RS07855	COG2264	protein methyltransferase activity
BA953_RS07860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BA953_RS07865	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BA953_RS07870	COG2199	diguanylate cyclase activity
BA953_RS07875	COG0789	Transcriptional regulator
BA953_RS07885	COG0151	Belongs to the GarS family
BA953_RS07900	COG1253	flavin adenine dinucleotide binding
BA953_RS07910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BA953_RS07915	COG1573	uracil-dna glycosylase
BA953_RS07920	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BA953_RS07925	COG1695	Transcriptional regulator
BA953_RS07930	COG1045	serine acetyltransferase
BA953_RS07945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA953_RS07980	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BA953_RS07985	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BA953_RS07990	COG1053	succinate dehydrogenase
BA953_RS07995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BA953_RS08000	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BA953_RS08020	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BA953_RS08025	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BA953_RS08030	COG1609	Transcriptional regulator
BA953_RS08035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BA953_RS08040	COG0254	rRNA binding
BA953_RS08045	COG0281	malic enzyme
BA953_RS08050	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
BA953_RS08055	COG0626	cystathionine gamma-synthase activity
BA953_RS08060	COG0460	homoserine dehydrogenase
BA953_RS08060	COG0527	aspartate kinase activity
BA953_RS08065	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BA953_RS08070	COG3074	FtsZ-dependent cytokinesis
BA953_RS08075	COG1494	fructose-1,6-bisphosphatase
BA953_RS08085	COG2801	Transposase and inactivated derivatives
BA953_RS08105	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BA953_RS08120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BA953_RS08125	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BA953_RS08125	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BA953_RS08130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BA953_RS08135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BA953_RS08140	COG2801	Transposase and inactivated derivatives
BA953_RS08185	COG0367	asparagine synthase
BA953_RS08215	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BA953_RS08225	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BA953_RS08230	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BA953_RS08260	COG0859	PFAM glycosyl transferase family 9
BA953_RS08275	COG1519	Transferase
BA953_RS08290	COG3642	lipopolysaccharide core region biosynthetic process
BA953_RS08295	COG0859	PFAM glycosyl transferase family 9
BA953_RS08300	COG0463	Glycosyl transferase, family 2
BA953_RS08305	COG0859	PFAM glycosyl transferase family 9
BA953_RS08310	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BA953_RS08330	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BA953_RS08335	COG2003	Belongs to the UPF0758 family
BA953_RS08340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BA953_RS08345	COG1309	transcriptional regulator
BA953_RS08350	COG1560	Kdo2-lipid A biosynthetic process
BA953_RS08355	COG1560	Kdo2-lipid A biosynthetic process
BA953_RS08360	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BA953_RS08365	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BA953_RS08370	COG1561	YicC-like family, N-terminal region
BA953_RS08375	COG2252	PERMEase
BA953_RS08385	COG0848	biopolymer transport protein
BA953_RS08405	COG1629	transport
BA953_RS08405	COG4206	TonB-dependent receptor
BA953_RS08415	COG1595	DNA-templated transcription, initiation
BA953_RS08420	COG0194	GDP metabolic process
BA953_RS08425	COG1758	RNA polymerase activity
BA953_RS08430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BA953_RS08435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BA953_RS08440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BA953_RS08445	COG1218	3'(2'),5'-bisphosphate nucleotidase
BA953_RS08450	COG0494	nUDIX hydrolase
BA953_RS08455	COG0316	Belongs to the HesB IscA family
BA953_RS08455	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BA953_RS08465	COG0596	Alpha beta hydrolase
BA953_RS08475	COG2183	response to ionizing radiation
BA953_RS08485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BA953_RS08505	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BA953_RS08510	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BA953_RS08515	COG3156	type II secretion system protein K
BA953_RS08520	COG4795	General secretion pathway protein
BA953_RS08525	COG2165	general secretion pathway protein
BA953_RS08530	COG2165	general secretion pathway protein
BA953_RS08535	COG2165	general secretion pathway protein
BA953_RS08540	COG1459	type II secretion system
BA953_RS08545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BA953_RS08555	COG3031	protein transport across the cell outer membrane
BA953_RS08560	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BA953_RS08570	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BA953_RS08580	COG0456	acetyltransferase
BA953_RS08585	COG1490	D-aminoacyl-tRNA deacylase activity
BA953_RS08590	COG1295	ribonuclease BN
BA953_RS08600	COG1217	gtp-binding protein TYPA
BA953_RS08605	COG0174	glutamine synthetase
BA953_RS08610	COG3852	Histidine kinase
BA953_RS08615	COG2204	response regulator
BA953_RS08625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BA953_RS08665	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BA953_RS08680	COG0408	coproporphyrinogen oxidase activity
BA953_RS08690	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BA953_RS08695	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BA953_RS08700	COG0551	DNA topoisomerase type I activity
BA953_RS08705	COG2922	Belongs to the Smg family
BA953_RS08710	COG0758	DNA mediated transformation
BA953_RS08725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BA953_RS08725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BA953_RS08730	COG0569	domain protein
BA953_RS08735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BA953_RS08745	COG1272	protein, Hemolysin III
BA953_RS08750	COG4326	sporulation control protein
BA953_RS08760	COG3084	Protein conserved in bacteria
BA953_RS08880	COG2932	Transcriptional regulator
BA953_RS08885	COG4974	Belongs to the 'phage' integrase family
BA953_RS08890	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BA953_RS08895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BA953_RS08900	COG3385	transposase activity
BA953_RS08905	COG0204	Acyl-transferase
BA953_RS08915	COG0606	chelatase, subunit chli
BA953_RS08925	COG3978	acetolactate synthase activity
BA953_RS08930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BA953_RS08935	COG0129	dihydroxy-acid dehydratase activity
BA953_RS08945	COG0604	alcohol dehydrogenase
BA953_RS08960	COG0425	Belongs to the sulfur carrier protein TusA family
BA953_RS08970	COG2119	membrane
BA953_RS08975	COG0752	glycyl-tRNA synthetase alpha subunit
BA953_RS08980	COG0751	glycine-tRNA ligase activity
BA953_RS08985	COG3977	Valine--pyruvate aminotransferase
BA953_RS08990	COG0071	Belongs to the small heat shock protein (HSP20) family
BA953_RS08995	COG0187	DNA topoisomerase II activity
BA953_RS09000	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BA953_RS09005	COG0592	DNA-directed DNA polymerase activity
BA953_RS09025	COG1126	abc transporter atp-binding protein
BA953_RS09030	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BA953_RS09040	COG0706	membrane insertase activity
BA953_RS09045	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BA953_RS09050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BA953_RS09055	COG0445	tRNA wobble uridine modification
BA953_RS09060	COG0357	Ribosomal RNA small subunit methyltransferase G
BA953_RS09065	COG1192	Involved in chromosome partitioning
BA953_RS09070	COG1475	DNA binding
BA953_RS09075	COG3312	ion transport
BA953_RS09095	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BA953_RS09100	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BA953_RS09105	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BA953_RS09110	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BA953_RS09115	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BA953_RS09125	COG0765	amino acid transport
BA953_RS09135	COG2814	Major facilitator Superfamily
BA953_RS09140	COG0583	DNA-binding transcription factor activity
BA953_RS09150	COG0183	Belongs to the thiolase family
BA953_RS09160	COG1739	Uncharacterized protein family UPF0029
BA953_RS09165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BA953_RS09220	COG2132	Multicopper oxidase
BA953_RS09240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BA953_RS09250	COG2022	thiamine diphosphate biosynthetic process
BA953_RS09260	COG0006	proline dipeptidase activity
BA953_RS09260	COG0006	proline dipeptidase activity
BA953_RS09280	COG1522	sequence-specific DNA binding
BA953_RS09285	COG5001	Diguanylate cyclase
BA953_RS09285	COG5002	protein histidine kinase activity
BA953_RS09290	COG0742	ribosomal rna small subunit methyltransferase
BA953_RS09305	COG0589	response to stress
BA953_RS09310	COG1528	Iron-storage protein
BA953_RS09320	COG2081	HI0933 family
BA953_RS09350	COG1639	'signal transduction protein
BA953_RS09360	COG1322	Protein conserved in bacteria
BA953_RS09365	COG2226	methyltransferase
BA953_RS09380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BA953_RS09385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BA953_RS09390	COG0805	protein transport
BA953_RS09395	COG0084	hydrolase, TatD family'
BA953_RS09410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BA953_RS09410	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BA953_RS09440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BA953_RS09445	COG0583	DNA-binding transcription factor activity
BA953_RS09450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BA953_RS09455	COG2960	long-chain fatty acid transporting porin activity
BA953_RS09460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA953_RS09465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA953_RS09470	COG1309	transcriptional regulator
BA953_RS09515	COG0747	negative chemotaxis
BA953_RS09520	COG0601	transmembrane transport
BA953_RS09525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA953_RS09540	COG0745	RESPONSE REGULATOR receiver
BA953_RS09555	COG0477	Major facilitator Superfamily
BA953_RS09565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA953_RS09565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BA953_RS09565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BA953_RS09570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BA953_RS09575	COG3537	Alpha-1,2-mannosidase
BA953_RS09585	COG3537	Alpha-1,2-mannosidase
BA953_RS09590	COG2207	Transcriptional regulator
BA953_RS09600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BA953_RS09605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BA953_RS09610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BA953_RS09615	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BA953_RS09635	COG3220	belongs to the UPF0276 family
BA953_RS09645	COG0210	DNA helicase
BA953_RS09660	COG0405	Gamma-glutamyltransferase
BA953_RS09665	COG1280	lysine exporter protein (LysE YggA)
BA953_RS09675	COG2962	Rard protein
BA953_RS09680	COG0514	ATP-dependent DNA helicase (RecQ)
BA953_RS09690	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BA953_RS09695	COG0248	Ppx GppA phosphatase
BA953_RS09705	COG3118	belongs to the thioredoxin family
BA953_RS09720	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BA953_RS09780	COG3071	HemY protein
BA953_RS09785	COG2959	enzyme of heme biosynthesis
BA953_RS09790	COG1587	Uroporphyrinogen-III synthase
BA953_RS09795	COG0181	hydroxymethylbilane synthase activity
BA953_RS09800	COG3072	Adenylate cyclase
BA953_RS09805	COG1965	Belongs to the frataxin family
BA953_RS09815	COG0019	diaminopimelate decarboxylase activity
BA953_RS09820	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BA953_RS09830	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BA953_RS09835	COG1011	Hydrolase
BA953_RS09840	COG2200	EAL domain
BA953_RS09840	COG2199	diguanylate cyclase activity
BA953_RS09840	COG3287	FIST C domain
BA953_RS09845	COG3148	PFAM DTW domain containing protein
BA953_RS09860	COG0561	phosphatase activity
BA953_RS09870	COG1280	lysine exporter protein (LysE YggA)
BA953_RS09875	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BA953_RS09880	COG0640	Transcriptional regulator
BA953_RS09885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BA953_RS09930	COG2095	MarC family integral membrane protein
BA953_RS09940	COG0742	ribosomal rna small subunit methyltransferase
BA953_RS09945	COG0552	protein localization to endoplasmic reticulum
BA953_RS09950	COG2884	Cell division ATP-binding protein ftsE
BA953_RS09955	COG2177	Part of the ABC transporter FtsEX involved in
BA953_RS09960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BA953_RS09965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA953_RS09975	COG1580	Controls the rotational direction of flagella during chemotaxis
BA953_RS09980	COG3161	chorismate lyase activity
BA953_RS09985	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BA953_RS09990	COG2937	Belongs to the GPAT DAPAT family
BA953_RS09995	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BA953_RS10000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BA953_RS10010	COG0534	Mate efflux family protein
BA953_RS10015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BA953_RS10045	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BA953_RS10140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BA953_RS10150	COG0137	argininosuccinate synthase activity
BA953_RS10155	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BA953_RS10155	COG0165	Argininosuccinate lyase
BA953_RS10165	COG0251	oxidation-reduction process
BA953_RS10170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BA953_RS10175	COG0678	peroxiredoxin activity
BA953_RS10175	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BA953_RS10185	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BA953_RS10220	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BA953_RS10230	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BA953_RS10235	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BA953_RS10240	COG0546	phosphoglycolate phosphatase activity
BA953_RS10245	COG0180	Tryptophanyl-tRNA synthetase
BA953_RS10250	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BA953_RS10255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BA953_RS10260	COG2205	protein histidine kinase activity
BA953_RS10265	COG0745	RESPONSE REGULATOR receiver
BA953_RS10270	COG3678	ATP-independent chaperone mediated protein folding
BA953_RS10280	COG0205	6-phosphofructokinase activity
BA953_RS10285	COG1285	pathogenesis
BA953_RS10295	COG1509	lysine 2,3-aminomutase activity
BA953_RS10300	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BA953_RS10305	COG1575	Belongs to the MenA family. Type 1 subfamily
BA953_RS10310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BA953_RS10315	COG0534	Mate efflux family protein
BA953_RS10320	COG0149	triose-phosphate isomerase activity
BA953_RS10335	COG1072	(Pantothenic acid kinase))
BA953_RS10360	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BA953_RS10370	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BA953_RS10375	COG0250	Participates in transcription elongation, termination and antitermination
BA953_RS10390	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BA953_RS10400	COG0085	RNA polymerase activity
BA953_RS10410	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BA953_RS10415	COG2816	NAD+ diphosphatase activity
BA953_RS10435	COG4942	peptidase
BA953_RS10450	COG0840	transmembrane signaling receptor activity
BA953_RS10455	COG0471	metal ion transport
BA953_RS10455	COG0490	domain, Protein
BA953_RS10460	COG0688	phosphatidylethanolamine metabolic process
BA953_RS10465	COG1162	GTPase activity
BA953_RS10470	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BA953_RS10525	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BA953_RS10530	COG0802	atpase or kinase
BA953_RS10540	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BA953_RS10555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BA953_RS10560	COG0330	HflC and HflK could
BA953_RS10565	COG0330	HflC and HflK could
BA953_RS10570	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BA953_RS10575	COG2900	Belongs to the SlyX family
BA953_RS10585	COG0545	Peptidyl-prolyl cis-trans isomerase
BA953_RS10590	COG2964	Protein conserved in bacteria
BA953_RS10600	COG2923	Belongs to the DsrF TusC family
BA953_RS10605	COG2168	tRNA wobble position uridine thiolation
BA953_RS10615	COG0049	tRNA binding
BA953_RS10620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BA953_RS10625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BA953_RS10635	COG0360	Binds together with S18 to 16S ribosomal RNA
BA953_RS10655	COG0305	Participates in initiation and elongation during chromosome replication
BA953_RS10660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BA953_RS10665	COG0432	Pfam Uncharacterised protein family UPF0047
BA953_RS10690	COG1136	(ABC) transporter
BA953_RS10705	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BA953_RS10715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BA953_RS10720	COG0729	surface antigen
BA953_RS10730	COG2105	PFAM AIG2 family protein
BA953_RS10735	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BA953_RS10745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BA953_RS10750	COG0163	prenyltransferase activity
BA953_RS10755	COG4143	(ABC) transporter
BA953_RS10760	COG1178	ABC-type Fe3 transport system permease component
BA953_RS10765	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BA953_RS10770	COG3028	Belongs to the UPF0307 family
BA953_RS10775	COG0312	modulator of DNA gyrase
BA953_RS10780	COG0527	aspartate kinase activity
BA953_RS10785	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BA953_RS10795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BA953_RS10810	COG0629	single-stranded DNA binding
BA953_RS10815	COG2199	diguanylate cyclase activity
BA953_RS10815	COG2200	EAL domain
BA953_RS10840	COG3267	Type II secretory pathway component ExeA
BA953_RS10840	COG3409	Peptidoglycan-binding domain 1 protein
BA953_RS10850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BA953_RS10855	COG1459	type II secretion system
BA953_RS10865	COG2165	general secretion pathway protein
BA953_RS10900	COG1077	Cell shape determining protein MreB Mrl
BA953_RS10905	COG1792	Involved in formation and maintenance of cell shape
BA953_RS10910	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BA953_RS10915	COG0424	maF-like protein
BA953_RS10925	COG3164	Protein of unknown function
BA953_RS10930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BA953_RS10935	COG0312	modulator of DNA gyrase
BA953_RS10990	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BA953_RS11000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BA953_RS11005	COG2066	Belongs to the glutaminase family
BA953_RS11010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BA953_RS11015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BA953_RS11030	COG0762	integral membrane protein
BA953_RS11035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BA953_RS11040	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BA953_RS11055	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BA953_RS11060	COG1678	Uncharacterized ACR, COG1678
BA953_RS11065	COG0189	ligase activity
BA953_RS11070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BA953_RS11075	COG2356	endonuclease I
BA953_RS11080	COG3091	SprT-like family
BA953_RS11090	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BA953_RS11095	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BA953_RS11100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BA953_RS11110	COG0191	fructose-bisphosphate aldolase activity
BA953_RS11115	COG0668	transmembrane transport
BA953_RS11130	COG0583	DNA-binding transcription factor activity
BA953_RS11150	COG0469	pyruvate kinase activity
BA953_RS11155	COG1349	DNA-binding transcription factor activity
BA953_RS11160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BA953_RS11175	COG5002	protein histidine kinase activity
BA953_RS11180	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BA953_RS11190	COG0142	geranyltranstransferase activity
BA953_RS11195	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BA953_RS11205	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BA953_RS11210	COG2966	Psort location CytoplasmicMembrane, score
BA953_RS11215	COG3610	response to peptide
BA953_RS11225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BA953_RS11235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BA953_RS11240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BA953_RS11245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA953_RS11250	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BA953_RS11255	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BA953_RS11270	COG0358	DNA primase activity
BA953_RS11275	COG1610	YqeY-like protein
BA953_RS11280	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BA953_RS11285	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BA953_RS11290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BA953_RS11295	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BA953_RS11300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BA953_RS11305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BA953_RS11310	COG1968	undecaprenyl-diphosphatase activity
BA953_RS11315	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BA953_RS11320	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BA953_RS11330	COG0585	pseudouridine synthase activity
BA953_RS11335	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BA953_RS11345	COG4942	peptidase
BA953_RS11345	COG1388	LysM domain
BA953_RS11350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BA953_RS11355	COG4536	flavin adenine dinucleotide binding
BA953_RS11360	COG4137	Cytochrome C assembly protein
BA953_RS11365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BA953_RS11370	COG0228	four-way junction DNA binding
BA953_RS11380	COG0336	Belongs to the RNA methyltransferase TrmD family
BA953_RS11390	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BA953_RS11395	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BA953_RS11400	COG0237	dephospho-CoA kinase activity
BA953_RS11410	COG1459	type II secretion system
BA953_RS11415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BA953_RS11420	COG4969	Belongs to the N-Me-Phe pilin family
BA953_RS11425	COG0157	Belongs to the NadC ModD family
BA953_RS11430	COG3023	N-Acetylmuramoyl-L-alanine amidase
BA953_RS11440	COG4974	Belongs to the 'phage' integrase family
BA953_RS11445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BA953_RS11450	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BA953_RS11460	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BA953_RS11465	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA953_RS11470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BA953_RS11485	COG0288	reversible hydration of carbon dioxide
BA953_RS11490	COG0659	secondary active sulfate transmembrane transporter activity
BA953_RS11495	COG1131	(ABC) transporter
BA953_RS11500	COG0842	Transport permease protein
BA953_RS11510	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BA953_RS11515	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BA953_RS11530	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BA953_RS11540	COG1643	Atp-dependent helicase
BA953_RS11555	COG1049	propionate catabolic process, 2-methylcitrate cycle
BA953_RS11570	COG0004	ammonium transporteR
BA953_RS11575	COG1840	ABC-type Fe3 transport system, periplasmic component
BA953_RS11585	COG3842	ATPase activity
BA953_RS11590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BA953_RS11605	COG2971	BadF BadG BcrA BcrD
BA953_RS11615	COG4608	Belongs to the ABC transporter superfamily
BA953_RS11620	COG0444	Belongs to the ABC transporter superfamily
BA953_RS11635	COG0747	negative chemotaxis
BA953_RS11645	COG2813	Specifically methylates the guanine in position
BA953_RS11650	COG0628	permease
BA953_RS11660	COG0316	Belongs to the HesB IscA family
BA953_RS11675	COG0739	heme binding
BA953_RS11680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BA953_RS11690	COG2027	D-alanyl-D-alanine carboxypeptidase
BA953_RS11695	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BA953_RS11700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BA953_RS11705	COG1534	Rna-binding protein
BA953_RS11710	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BA953_RS11715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BA953_RS11720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BA953_RS11725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BA953_RS11750	COG0513	Belongs to the DEAD box helicase family
BA953_RS11765	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BA953_RS11770	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BA953_RS11775	COG0826	peptidase U32
BA953_RS11780	COG0826	peptidase U32
BA953_RS11790	COG3154	lipid carrier protein
BA953_RS11795	COG3153	acetyltransferase
BA953_RS11800	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BA953_RS11815	COG0779	Required for maturation of 30S ribosomal subunits
BA953_RS11820	COG0195	Participates in both transcription termination and antitermination
BA953_RS11845	COG0493	'glutamate synthase
BA953_RS11850	COG0067	glutamate synthase
BA953_RS11850	COG0069	glutamate synthase activity
BA953_RS11850	COG0070	glutamate synthase
BA953_RS11860	COG0067	glutamate synthase
BA953_RS11860	COG0070	glutamate synthase
BA953_RS11860	COG0069	glutamate synthase activity
BA953_RS11865	COG1242	4 iron, 4 sulfur cluster binding
BA953_RS11870	COG3706	GGDEF domain
BA953_RS11870	COG2203	Gaf domain
BA953_RS11870	COG5001	Diguanylate cyclase
BA953_RS11870	COG4251	negative regulation of phosphorylation
BA953_RS11875	COG5002	protein histidine kinase activity
BA953_RS11875	COG2198	Histidine kinase
BA953_RS11875	COG0784	Response regulator, receiver
BA953_RS11885	COG1538	Outer membrane efflux protein
BA953_RS11890	COG0494	nUDIX hydrolase
BA953_RS11895	COG3151	Protein conserved in bacteria
BA953_RS11905	COG3150	esterase
BA953_RS11920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BA953_RS11925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BA953_RS11930	COG3105	Protein conserved in bacteria
BA953_RS11935	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BA953_RS11950	COG0723	plastoquinol--plastocyanin reductase activity
BA953_RS11955	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BA953_RS11960	COG2857	Cytochrome c1
BA953_RS11965	COG0625	glutathione transferase activity
BA953_RS11970	COG2969	positive regulation of protein catabolic process
BA953_RS11980	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BA953_RS11990	COG3107	peptidoglycan biosynthetic process
BA953_RS11995	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BA953_RS12010	COG3116	cell division
BA953_RS12015	COG0768	penicillin binding
BA953_RS12020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BA953_RS12025	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BA953_RS12035	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BA953_RS12040	COG0772	Belongs to the SEDS family
BA953_RS12055	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BA953_RS12060	COG0849	cell division
BA953_RS12065	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BA953_RS12070	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BA953_RS12075	COG0653	protein targeting
BA953_RS12080	COG0494	nUDIX hydrolase
BA953_RS12090	COG0505	Belongs to the CarA family
BA953_RS12095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BA953_RS12100	COG0730	response to heat
BA953_RS12105	COG0583	DNA-binding transcription factor activity
BA953_RS12110	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
BA953_RS12120	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BA953_RS12135	COG1115	amino acid carrier protein
BA953_RS12140	COG3022	response to hydroperoxide
BA953_RS12145	COG0084	hydrolase, TatD family'
BA953_RS12150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA953_RS12165	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BA953_RS12170	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BA953_RS12175	COG0813	purine-nucleoside phosphorylase activity
BA953_RS12185	COG0560	Phosphoserine phosphatase
BA953_RS12195	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BA953_RS12200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BA953_RS12205	COG0693	protein deglycase activity
BA953_RS12210	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BA953_RS12225	COG1595	DNA-templated transcription, initiation
BA953_RS12240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BA953_RS12250	COG2813	Specifically methylates the guanine in position
BA953_RS12255	COG0271	Belongs to the BolA IbaG family
BA953_RS12260	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BA953_RS12265	COG1805	sodium ion transport
BA953_RS12280	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BA953_RS12285	COG2871	sodium ion transport
BA953_RS12290	COG1477	protein flavinylation
BA953_RS12305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BA953_RS12315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BA953_RS12330	COG0733	neurotransmitter:sodium symporter activity
BA953_RS12340	COG0189	ligase activity
BA953_RS12345	COG0189	ligase activity
BA953_RS12345	COG4067	protein conserved in archaea
BA953_RS12350	COG2195	Cleaves the N-terminal amino acid of tripeptides
BA953_RS12355	COG2252	PERMEase
BA953_RS12360	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BA953_RS12365	COG1073	alpha beta
BA953_RS12375	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BA953_RS12380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BA953_RS12385	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BA953_RS12390	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BA953_RS12390	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BA953_RS12410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BA953_RS12415	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BA953_RS12420	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BA953_RS12435	COG0024	Methionine aminopeptidase
BA953_RS12440	COG0052	Belongs to the universal ribosomal protein uS2 family
BA953_RS12445	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BA953_RS12450	COG0528	UMP kinase activity
BA953_RS12455	COG0233	cytoplasmic translational termination
BA953_RS12460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BA953_RS12465	COG0575	Belongs to the CDS family
BA953_RS12475	COG0750	zinc metalloprotease
BA953_RS12480	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BA953_RS12485	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BA953_RS12490	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BA953_RS12495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BA953_RS12510	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BA953_RS12515	COG0587	DNA-directed DNA polymerase activity
BA953_RS12520	COG0825	malonyl-CoA metabolic process
BA953_RS12535	COG0347	Belongs to the P(II) protein family
BA953_RS12540	COG3021	interspecies interaction between organisms
BA953_RS12550	COG0741	lytic transglycosylase activity
BA953_RS12550	COG1388	LysM domain
BA953_RS12555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA953_RS12560	COG2226	methyltransferase
BA953_RS12565	COG0328	RNA-DNA hybrid ribonuclease activity
BA953_RS12580	COG1960	acyl-CoA dehydrogenase activity
BA953_RS12585	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BA953_RS12590	COG0121	glutamine amidotransferase
BA953_RS12600	COG1720	tRNA m6t6A37 methyltransferase activity
BA953_RS12605	COG0254	rRNA binding
BA953_RS12615	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BA953_RS12625	COG1464	Belongs to the NlpA lipoprotein family
BA953_RS12630	COG2011	ABC-type metal ion transport system permease component
BA953_RS12635	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BA953_RS12640	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BA953_RS12650	COG1609	Transcriptional regulator
BA953_RS12655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA953_RS12655	COG1263	PTS System
BA953_RS12660	COG0366	Alpha amylase catalytic
BA953_RS12685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA953_RS12690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA953_RS12700	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BA953_RS12715	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BA953_RS12725	COG2921	Belongs to the UPF0250 family
BA953_RS12730	COG1686	Belongs to the peptidase S11 family
BA953_RS12735	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BA953_RS12740	COG0772	Belongs to the SEDS family
BA953_RS12745	COG0768	penicillin binding
BA953_RS12750	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BA953_RS12755	COG0799	negative regulation of ribosome biogenesis
BA953_RS12760	COG1466	dna polymerase III delta subunit
BA953_RS12765	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BA953_RS12770	COG0495	leucyl-tRNA aminoacylation
BA953_RS12780	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BA953_RS12785	COG4535	Mg2 and Co2 transporter CorC
BA953_RS12790	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BA953_RS12795	COG1702	phosphate starvation-inducible protein PhoH
BA953_RS12805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BA953_RS12810	COG2190	(PTS) system
BA953_RS12815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BA953_RS12820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA953_RS12825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BA953_RS12830	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BA953_RS12835	COG3115	cell septum assembly
BA953_RS12840	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BA953_RS12860	COG0330	HflC and HflK could
BA953_RS12865	COG3118	belongs to the thioredoxin family
BA953_RS12870	COG0300	oxidoreductase activity
BA953_RS12875	COG1090	epimerase
BA953_RS12900	COG0622	Phosphoesterase
BA953_RS12920	COG3710	Transcriptional regulator
BA953_RS12925	COG0326	Molecular chaperone. Has ATPase activity
BA953_RS12935	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BA953_RS12955	COG2217	Heavy metal translocating P-type atpase
BA953_RS12955	COG2608	mercury ion transmembrane transporter activity
BA953_RS12975	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BA953_RS12975	COG2885	chlorophyll binding
BA953_RS12995	COG2194	sulfuric ester hydrolase activity
BA953_RS13005	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BA953_RS13045	COG2747	anti-sigma28 factor FlgM
BA953_RS13055	COG0784	Response regulator, receiver
BA953_RS13055	COG0835	chemotaxis
BA953_RS13060	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BA953_RS13065	COG1815	bacterial-type flagellum-dependent cell motility
BA953_RS13085	COG4787	bacterial-type flagellum-dependent cell motility
BA953_RS13095	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BA953_RS13100	COG1706	bacterial-type flagellum-dependent cell motility
BA953_RS13105	COG1705	Flagellar rod assembly protein muramidase FlgJ
BA953_RS13105	COG3951	Flagellar rod assembly protein muramidase FlgJ
BA953_RS13115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BA953_RS13120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BA953_RS13235	COG0012	GTP binding
BA953_RS13245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BA953_RS13250	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BA953_RS13260	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BA953_RS13270	COG2890	protein-(glutamine-N5) methyltransferase activity
BA953_RS13280	COG2912	Transglutaminase-like superfamily
BA953_RS13285	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BA953_RS13295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BA953_RS13320	COG1393	Belongs to the ArsC family
BA953_RS13325	COG4783	chaperone-mediated protein folding
BA953_RS13345	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BA953_RS13350	COG2716	regulation of RNA biosynthetic process
BA953_RS13360	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BA953_RS13365	COG2056	Na+-H+ antiporter family
BA953_RS13385	COG0346	lactoylglutathione lyase activity
BA953_RS13390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BA953_RS13395	COG4660	Part of a membrane complex involved in electron transport
BA953_RS13400	COG4659	FMN binding
BA953_RS13405	COG4658	electron transport chain
BA953_RS13410	COG4656	Part of a membrane complex involved in electron transport
BA953_RS13420	COG4657	Part of a membrane complex involved in electron transport
BA953_RS13445	COG1815	bacterial-type flagellum-dependent cell motility
BA953_RS13450	COG1558	bacterial-type flagellum-dependent cell motility
BA953_RS13460	COG1749	Flagellar hook protein flgE
BA953_RS13465	COG4787	bacterial-type flagellum-dependent cell motility
BA953_RS13470	COG4786	Flagellar basal body rod
BA953_RS13475	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BA953_RS13480	COG1706	bacterial-type flagellum-dependent cell motility
BA953_RS13510	COG1360	Flagellar Motor Protein
BA953_RS13515	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BA953_RS13520	COG1191	sigma factor activity
BA953_RS13525	COG1580	Controls the rotational direction of flagella during chemotaxis
BA953_RS13540	COG1516	flagellar protein fliS
BA953_RS13545	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BA953_RS13550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BA953_RS13565	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BA953_RS13575	COG1987	bacterial-type flagellum assembly
BA953_RS13595	COG2885	chlorophyll binding
BA953_RS13640	COG0739	heme binding
BA953_RS13675	COG2977	Belongs to the P-Pant transferase superfamily
BA953_RS13705	COG0328	RNA-DNA hybrid ribonuclease activity
BA953_RS13755	COG0582	viral genome integration into host DNA
BA953_RS13765	COG0556	nucleotide-excision repair
BA953_RS13775	COG2198	Histidine kinase
BA953_RS13780	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BA953_RS13785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BA953_RS13790	COG0521	Mo-molybdopterin cofactor biosynthetic process
BA953_RS13800	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BA953_RS13805	COG0314	molybdopterin synthase activity
BA953_RS13820	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BA953_RS13820	COG0517	IMP dehydrogenase activity
BA953_RS13820	COG0617	tRNA 3'-terminal CCA addition
BA953_RS13870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA953_RS13870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA953_RS13875	COG0489	protein tyrosine kinase activity
BA953_RS13880	COG0572	uridine kinase
BA953_RS13885	COG2982	Protein involved in outer membrane biogenesis
BA953_RS13895	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BA953_RS13905	COG0302	gtp cyclohydrolase
BA953_RS13910	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BA953_RS13915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BA953_RS13915	COG0302	gtp cyclohydrolase
BA953_RS13920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BA953_RS13940	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BA953_RS13945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BA953_RS13955	COG1881	PFAM PEBP family protein
BA953_RS13965	COG0123	including yeast histone deacetylase and acetoin utilization protein
BA953_RS13995	COG3852	Histidine kinase
BA953_RS14010	COG0840	transmembrane signaling receptor activity
BA953_RS14030	COG3083	sulfuric ester hydrolase activity
BA953_RS14035	COG3082	Protein of unknown function (DUF1414)
BA953_RS14040	COG3081	Nucleoid-associated protein
BA953_RS14060	COG1757	Na H antiporter
BA953_RS14065	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BA953_RS14070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BA953_RS14075	COG2095	MarC family integral membrane protein
BA953_RS14080	COG1454	alcohol dehydrogenase
BA953_RS14080	COG1012	belongs to the aldehyde dehydrogenase family
BA953_RS14085	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BA953_RS14090	COG2894	cell division
BA953_RS14095	COG0850	regulation of cytokinetic process
BA953_RS14100	COG3100	YcgL domain-containing protein
BA953_RS14105	COG2951	lytic endotransglycosylase activity
BA953_RS14110	COG0583	DNA-binding transcription factor activity
BA953_RS14115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA953_RS14125	COG2983	Belongs to the UPF0260 family
BA953_RS14130	COG0668	transmembrane transport
BA953_RS14150	COG1785	Belongs to the alkaline phosphatase family
BA953_RS14165	COG2226	methyltransferase
BA953_RS14170	COG0840	transmembrane signaling receptor activity
BA953_RS14185	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BA953_RS14195	COG3139	Protein of unknown function (DUF1315)
BA953_RS14200	COG3012	SEC-C Motif Domain Protein
BA953_RS14205	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BA953_RS14210	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BA953_RS14215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BA953_RS14220	COG0215	cysteine-tRNA ligase activity
BA953_RS14225	COG1435	thymidine kinase activity
BA953_RS14230	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BA953_RS14235	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BA953_RS14240	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BA953_RS14250	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BA953_RS14260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BA953_RS14265	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BA953_RS14270	COG0297	glycogen (starch) synthase activity
BA953_RS14290	COG3070	regulator of competence-specific genes
BA953_RS14305	COG0745	RESPONSE REGULATOR receiver
BA953_RS14310	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BA953_RS14315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BA953_RS14325	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BA953_RS14330	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BA953_RS14360	COG0189	ligase activity
BA953_RS14360	COG4067	protein conserved in archaea
BA953_RS14365	COG0500	methyltransferase
BA953_RS14375	COG1801	Protein of unknown function DUF72
BA953_RS14385	COG1187	pseudouridine synthase activity
BA953_RS14395	COG1278	Cold shock
BA953_RS14400	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BA953_RS14405	COG0542	response to heat
BA953_RS14430	COG2116	formate transmembrane transporter activity
BA953_RS14435	COG0390	transport system, permease component
BA953_RS14440	COG4459	periplasmic nitrate reductase
BA953_RS14445	COG3005	denitrification pathway
BA953_RS14450	COG0243	molybdopterin cofactor binding
BA953_RS14465	COG4221	oxidoreductase activity
BA953_RS14485	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BA953_RS14490	COG0840	transmembrane signaling receptor activity
BA953_RS14495	COG0632	four-way junction helicase activity
BA953_RS14500	COG2255	four-way junction helicase activity
BA953_RS14505	COG1271	oxidase subunit
BA953_RS14510	COG1294	oxidase, subunit
BA953_RS14515	COG4890	Cyd operon protein YbgT
BA953_RS14525	COG0824	Thioesterase
BA953_RS14530	COG0811	peptide transport
BA953_RS14545	COG0823	Involved in the tonB-independent uptake of proteins
BA953_RS14550	COG2885	chlorophyll binding
BA953_RS14555	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BA953_RS14560	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BA953_RS14565	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BA953_RS14575	COG5640	endopeptidase activity
BA953_RS14590	COG5002	protein histidine kinase activity
BA953_RS14590	COG0784	Response regulator, receiver
BA953_RS14610	COG1902	pentaerythritol trinitrate reductase activity
BA953_RS14615	COG1881	PFAM PEBP family protein
BA953_RS14620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BA953_RS14635	COG1940	carbohydrate kinase activity
BA953_RS14650	COG3850	Histidine kinase
BA953_RS14650	COG5002	protein histidine kinase activity
BA953_RS14655	COG0745	RESPONSE REGULATOR receiver
BA953_RS14660	COG0463	Glycosyl transferase, family 2
BA953_RS14665	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BA953_RS14680	COG1960	acyl-CoA dehydrogenase activity
BA953_RS14685	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BA953_RS14695	COG0708	Exodeoxyribonuclease III
BA953_RS14700	COG0840	transmembrane signaling receptor activity
BA953_RS14705	COG2850	peptidyl-arginine hydroxylation
BA953_RS14720	COG0730	response to heat
BA953_RS14725	COG1199	ATP-dependent helicase activity
BA953_RS14740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BA953_RS14750	COG0156	8-amino-7-oxononanoate synthase activity
BA953_RS14755	COG1073	alpha beta
BA953_RS14755	COG2226	methyltransferase
BA953_RS14760	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BA953_RS14765	COG0501	Belongs to the peptidase M48B family
BA953_RS14790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BA953_RS14800	COG2268	Band 7 protein
BA953_RS14810	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BA953_RS14820	COG0482	sulfurtransferase activity
BA953_RS14830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA953_RS14840	COG1757	Na H antiporter
BA953_RS14850	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BA953_RS14860	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BA953_RS14860	COG0131	Imidazoleglycerol-phosphate dehydratase
BA953_RS14865	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BA953_RS14870	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BA953_RS14880	COG0140	phosphoribosyl-ATP diphosphatase activity
BA953_RS14880	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BA953_RS14885	COG0217	transcriptional regulatory protein
BA953_RS14895	COG1227	inorganic diphosphatase activity
BA953_RS14910	COG4172	Belongs to the ABC transporter superfamily
BA953_RS14935	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BA953_RS14940	COG1842	Phage shock protein A
BA953_RS14950	COG1983	PspC domain protein
BA953_RS14970	COG2818	Glycosylase
BA953_RS14980	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BA953_RS14985	COG0626	cystathionine gamma-synthase activity
BA953_RS14995	COG0733	neurotransmitter:sodium symporter activity
BA953_RS15000	COG0564	pseudouridine synthase activity
BA953_RS15005	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BA953_RS15010	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BA953_RS15015	COG4136	ATPase activity
BA953_RS15020	COG4135	transport system, permease component
BA953_RS15035	COG3313	Fe-S protein
BA953_RS15050	COG2350	Protein conserved in bacteria
BA953_RS15080	COG0776	regulation of translation
BA953_RS15090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BA953_RS15120	COG2197	response regulator
BA953_RS15125	COG0322	excinuclease ABC activity
BA953_RS15155	COG1902	pentaerythritol trinitrate reductase activity
BA953_RS15165	COG2133	pyrroloquinoline quinone binding
BA953_RS15190	COG3706	GGDEF domain
BA953_RS15200	COG0072	phenylalanine-tRNA ligase activity
BA953_RS15200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA953_RS15255	COG1741	Belongs to the pirin family
BA953_RS15260	COG1335	isochorismatase
BA953_RS15270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA953_RS15275	COG3710	Transcriptional regulator
BA953_RS15295	COG0583	DNA-binding transcription factor activity
BA953_RS15320	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BA953_RS15335	COG0583	DNA-binding transcription factor activity
BA953_RS15345	COG0277	FAD linked oxidase domain protein
BA953_RS15355	COG4211	Belongs to the binding-protein-dependent transport system permease family
BA953_RS15360	COG1129	ABC transporter
BA953_RS15370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA953_RS15375	COG3962	Belongs to the TPP enzyme family
BA953_RS15415	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BA953_RS15420	COG0183	Belongs to the thiolase family
BA953_RS15435	COG0583	DNA-binding transcription factor activity
BA953_RS15440	COG2814	Major facilitator Superfamily
BA953_RS15440	COG0477	Major facilitator Superfamily
BA953_RS15455	COG3962	Belongs to the TPP enzyme family
BA953_RS15460	COG0673	inositol 2-dehydrogenase activity
BA953_RS15465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA953_RS15490	COG3718	enzyme involved in inositol metabolism
BA953_RS15495	COG0673	inositol 2-dehydrogenase activity
BA953_RS15505	COG1216	Glycosyl transferase, family 2
BA953_RS15510	COG2223	nitrite transmembrane transporter activity
BA953_RS15520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BA953_RS15530	COG3437	response regulator, receiver
BA953_RS15535	COG0488	(ABC) transporter
BA953_RS15550	COG1858	cytochrome C peroxidase
BA953_RS15555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BA953_RS15560	COG1737	Transcriptional regulator
BA953_RS15565	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BA953_RS15570	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BA953_RS15580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA953_RS15620	COG0745	RESPONSE REGULATOR receiver
BA953_RS15625	COG2205	protein histidine kinase activity
BA953_RS15640	COG1609	Transcriptional regulator
BA953_RS15645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA953_RS15660	COG1609	Transcriptional regulator
BA953_RS15670	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BA953_RS15685	COG2267	carboxylic ester hydrolase activity
BA953_RS15690	COG0583	DNA-binding transcription factor activity
BA953_RS15700	COG1012	belongs to the aldehyde dehydrogenase family
BA953_RS15710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BA953_RS15735	COG0583	DNA-binding transcription factor activity
BA953_RS15750	COG0352	thiamine-phosphate diphosphorylase activity
BA953_RS15755	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BA953_RS15760	COG1280	lysine exporter protein (LysE YggA)
BA953_RS15765	COG1115	amino acid carrier protein
BA953_RS15790	COG3300	MHYT domain
BA953_RS15790	COG5001	Diguanylate cyclase
BA953_RS15845	COG0778	Nitroreductase
BA953_RS15850	COG4580	involved in the transport of maltose and maltodextrins
BA953_RS15865	COG0519	Catalyzes the synthesis of GMP from XMP
BA953_RS15870	COG0242	peptide deformylase activity
BA953_RS15920	COG0307	riboflavin synthase, alpha
BA953_RS15925	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BA953_RS15955	COG1335	isochorismatase
BA953_RS15965	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BA953_RS15970	COG0583	DNA-binding transcription factor activity
BA953_RS16000	COG0463	Glycosyl transferase, family 2
BA953_RS16020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA953_RS16025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA953_RS16065	COG1061	Type III restriction enzyme res subunit
BA953_RS16075	COG2814	Major facilitator Superfamily
BA953_RS16085	COG0702	epimerase
BA953_RS16090	COG0534	Mate efflux family protein
BA953_RS16095	COG1136	(ABC) transporter
BA953_RS16100	COG0577	efflux transmembrane transporter activity
BA953_RS16140	COG0019	diaminopimelate decarboxylase activity
BA953_RS16165	COG0633	Ferredoxin
BA953_RS16170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BA953_RS16175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BA953_RS16180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BA953_RS16550	COG4774	siderophore transport
BA953_RS16830	COG0488	(ABC) transporter
BA953_RS16975	COG0243	molybdopterin cofactor binding
BA953_RS17600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BA953_RS17860	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BA953_RS18925	COG0840	transmembrane signaling receptor activity
BA953_RS19055	COG0814	amino acid
BA953_RS19120	COG1448	Aminotransferase
BA953_RS19775	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BA953_RS20275	COG0616	signal peptide processing
BA953_RS20410	COG0446	pyridine nucleotide-disulphide oxidoreductase
BA953_RS20410	COG1902	pentaerythritol trinitrate reductase activity
BA953_RS20580	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BA953_RS20745	COG0778	Nitroreductase
BA953_RS20770	COG2067	long-chain fatty acid transport protein
BA953_RS20795	COG1138	Cytochrome C-type biogenesis protein
BA953_RS20965	COG0285	dihydrofolate synthase activity
BA953_RS21410	COG0567	Dehydrogenase, E1 component
BA953_RS21570	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BA953_RS21570	COG0047	phosphoribosylformylglycinamidine synthase activity
BA953_RS22005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BA953_RS22010	COG1074	ATP-dependent DNA helicase activity
BA953_RS22355	COG3408	Glycogen debranching enzyme
BA953_RS22355	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BA953_RS22605	COG1605	Chorismate mutase
BA953_RS22605	COG0077	Prephenate dehydratase
BA953_RS22620	COG5001	Diguanylate cyclase
BA953_RS22740	COG0728	peptidoglycan biosynthetic process
BA953_RS22930	COG0148	phosphopyruvate hydratase activity
BA953_RS23000	COG3026	antisigma factor binding
BA953_RS23010	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BA953_RS23315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BA953_RS23465	COG1410	methionine synthase
BA953_RS23465	COG0646	methionine synthase
BA953_RS23470	COG0646	methionine synthase
BA953_RS23470	COG1410	methionine synthase
BA953_RS23605	COG4999	Histidine kinase
BA953_RS23605	COG3850	Histidine kinase
BA953_RS23605	COG2205	protein histidine kinase activity
BA953_RS23605	COG3437	response regulator, receiver
BA953_RS23660	COG0737	Belongs to the 5'-nucleotidase family
BA953_RS23875	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BA953_RS23945	COG0784	Response regulator, receiver
BA953_RS23945	COG2198	Histidine kinase
BA953_RS23945	COG2205	protein histidine kinase activity
BA953_RS24105	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BA953_RS24380	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BA953_RS24470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BA953_RS24700	COG2814	Major facilitator Superfamily
BA953_RS24780	COG0811	peptide transport