locus-tag	class	description
G3U99_RS00025	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G3U99_RS00035	COG1677	Flagellar hook-basal body complex protein FliE
G3U99_RS00045	COG4191	Histidine kinase
G3U99_RS00055	COG1516	flagellar protein fliS
G3U99_RS00065	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G3U99_RS00075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G3U99_RS00090	COG2837	iron assimilation
G3U99_RS00100	COG4235	cytochrome complex assembly
G3U99_RS00100	COG3088	subunit of a heme lyase
G3U99_RS00105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3U99_RS00110	COG1138	Cytochrome C-type biogenesis protein
G3U99_RS00115	COG3301	Polysulphide reductase, NrfD
G3U99_RS00120	COG0437	4 iron, 4 sulfur cluster binding
G3U99_RS00125	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
G3U99_RS00130	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
G3U99_RS00155	COG1393	Belongs to the ArsC family
G3U99_RS00160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G3U99_RS00175	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
G3U99_RS00185	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3U99_RS00185	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3U99_RS00200	COG1611	Belongs to the LOG family
G3U99_RS00205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3U99_RS00230	COG0583	DNA-binding transcription factor activity
G3U99_RS00235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3U99_RS00235	COG0301	tRNA thio-modification
G3U99_RS00245	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G3U99_RS00255	COG0142	geranyltranstransferase activity
G3U99_RS00265	COG0564	pseudouridine synthase activity
G3U99_RS00270	COG3098	single-species biofilm formation
G3U99_RS00305	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3U99_RS00310	COG0567	Dehydrogenase, E1 component
G3U99_RS00315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3U99_RS00320	COG1053	succinate dehydrogenase
G3U99_RS00325	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G3U99_RS00340	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G3U99_RS00350	COG0033	Phosphoglucomutase
G3U99_RS00355	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
G3U99_RS00360	COG0596	Alpha beta hydrolase
G3U99_RS00370	COG0716	FMN binding
G3U99_RS00390	COG2190	(PTS) system
G3U99_RS00390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G3U99_RS00390	COG1263	PTS System
G3U99_RS00395	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G3U99_RS00400	COG1940	carbohydrate kinase activity
G3U99_RS00400	COG1846	Transcriptional regulator
G3U99_RS00405	COG4651	solute:proton antiporter activity
G3U99_RS00405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G3U99_RS00410	COG0367	asparagine synthase
G3U99_RS00415	COG3104	oligopeptide transport
G3U99_RS00440	COG2840	Smr protein MutS2
G3U99_RS00445	COG1187	pseudouridine synthase activity
G3U99_RS00450	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G3U99_RS00455	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G3U99_RS00460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G3U99_RS00485	COG0047	phosphoribosylformylglycinamidine synthase activity
G3U99_RS00485	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G3U99_RS00490	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G3U99_RS00500	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
G3U99_RS00520	COG4970	Tfp pilus assembly protein FimT
G3U99_RS00535	COG0443	Heat shock 70 kDa protein
G3U99_RS00540	COG1301	dicarboxylic acid transport
G3U99_RS00545	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G3U99_RS00560	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3U99_RS00565	COG2914	Belongs to the UPF0125 (RnfH) family
G3U99_RS00570	COG2867	negative regulation of translational initiation
G3U99_RS00595	COG0668	transmembrane transport
G3U99_RS00600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3U99_RS00620	COG0204	Acyl-transferase
G3U99_RS00625	COG0835	chemotaxis
G3U99_RS00625	COG0784	Response regulator, receiver
G3U99_RS00630	COG2873	o-acetylhomoserine
G3U99_RS00650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3U99_RS00655	COG1115	amino acid carrier protein
G3U99_RS00660	COG1584	GPR1 FUN34 yaaH family protein
G3U99_RS00675	COG0517	IMP dehydrogenase activity
G3U99_RS00675	COG0516	GMP reductase activity
G3U99_RS00690	COG2199	diguanylate cyclase activity
G3U99_RS00690	COG2203	Gaf domain
G3U99_RS00700	COG1160	GTP binding
G3U99_RS00705	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3U99_RS00710	COG2976	Protein conserved in bacteria
G3U99_RS00715	COG0124	histidyl-tRNA synthetase
G3U99_RS00720	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G3U99_RS00725	COG1426	Protein conserved in bacteria
G3U99_RS00735	COG2166	iron-sulfur cluster assembly
G3U99_RS00740	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G3U99_RS00745	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
G3U99_RS00765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G3U99_RS00770	COG1074	ATP-dependent DNA helicase activity
G3U99_RS00775	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G3U99_RS00795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_RS00800	COG1309	transcriptional regulator
G3U99_RS00805	COG3141	response to X-ray
G3U99_RS00820	COG0704	Plays a role in the regulation of phosphate uptake
G3U99_RS00825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G3U99_RS00830	COG0581	inorganic phosphate transmembrane transporter activity
G3U99_RS00840	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G3U99_RS00845	COG0248	Ppx GppA phosphatase
G3U99_RS00855	COG5002	protein histidine kinase activity
G3U99_RS00860	COG0745	RESPONSE REGULATOR receiver
G3U99_RS00875	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G3U99_RS00895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3U99_RS00900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3U99_RS00905	COG1862	Preprotein translocase
G3U99_RS00915	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G3U99_RS00920	COG0517	IMP dehydrogenase activity
G3U99_RS00930	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G3U99_RS00935	COG0583	DNA-binding transcription factor activity
G3U99_RS00940	COG0450	alkyl hydroperoxide reductase
G3U99_RS00945	COG2171	N-acyltransferase activity
G3U99_RS00955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_RS00965	COG2207	Transcriptional regulator
G3U99_RS00970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_RS00970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_RS00970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_RS00985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3U99_RS00995	COG2017	converts alpha-aldose to the beta-anomer
G3U99_RS01005	COG1085	galactose-1-phosphate uridylyltransferase
G3U99_RS01010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G3U99_RS01015	COG1609	Transcriptional regulator
G3U99_RS01020	COG3250	beta-galactosidase activity
G3U99_RS01025	COG2731	YhcH YjgK YiaL family protein
G3U99_RS01030	COG0531	amino acid
G3U99_RS01035	COG1309	transcriptional regulator
G3U99_RS01050	COG3408	Glycogen debranching enzyme
G3U99_RS01050	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
G3U99_RS01060	COG2211	Major facilitator Superfamily
G3U99_RS01065	COG1486	melibiose metabolic process
G3U99_RS01070	COG2169	Transcriptional regulator
G3U99_RS01135	COG4964	Belongs to the GSP D family
G3U99_RS01165	COG2169	Transcriptional regulator
G3U99_RS01170	COG1022	Amp-dependent synthetase and ligase
G3U99_RS01175	COG0583	DNA-binding transcription factor activity
G3U99_RS01185	COG0583	DNA-binding transcription factor activity
G3U99_RS01190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G3U99_RS01200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G3U99_RS01205	COG2975	iron-sulfur cluster assembly
G3U99_RS01210	COG0633	Ferredoxin
G3U99_RS01215	COG0443	Heat shock 70 kDa protein
G3U99_RS01230	COG0822	iron-sulfur transferase activity
G3U99_RS01235	COG1104	cysteine desulfurase activity
G3U99_RS01250	COG0483	inositol monophosphate 1-phosphatase activity
G3U99_RS01290	COG0542	response to heat
G3U99_RS01300	COG0564	pseudouridine synthase activity
G3U99_RS01305	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3U99_RS01310	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G3U99_RS01315	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G3U99_RS01320	COG1605	Chorismate mutase
G3U99_RS01320	COG0077	Prephenate dehydratase
G3U99_RS01325	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G3U99_RS01330	COG5001	Diguanylate cyclase
G3U99_RS01335	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
G3U99_RS01340	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
G3U99_RS01350	COG0488	(ABC) transporter
G3U99_RS01360	COG0739	heme binding
G3U99_RS01365	COG0287	Prephenate dehydrogenase
G3U99_RS01365	COG1605	Chorismate mutase
G3U99_RS01370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3U99_RS01375	COG3275	phosphorelay sensor kinase activity
G3U99_RS01380	COG3279	Response regulator of the LytR AlgR family
G3U99_RS01390	COG1737	Transcriptional regulator
G3U99_RS01405	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G3U99_RS01410	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G3U99_RS01420	COG1966	Carbon starvation protein
G3U99_RS01425	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G3U99_RS01430	COG1047	Peptidyl-prolyl cis-trans
G3U99_RS01445	COG0196	riboflavin kinase activity
G3U99_RS01450	COG0728	peptidoglycan biosynthetic process
G3U99_RS01455	COG0268	Binds directly to 16S ribosomal RNA
G3U99_RS01460	COG0640	Transcriptional regulator
G3U99_RS01465	COG0583	DNA-binding transcription factor activity
G3U99_RS01470	COG1283	sodium-dependent phosphate transmembrane transporter activity
G3U99_RS01475	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G3U99_RS01485	COG0730	response to heat
G3U99_RS01500	COG3066	DNA modification
G3U99_RS01510	COG0667	Aldo Keto reductase
G3U99_RS01520	COG2204	response regulator
G3U99_RS01525	COG0534	Mate efflux family protein
G3U99_RS01530	COG1846	Transcriptional regulator
G3U99_RS01545	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G3U99_RS01555	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G3U99_RS01560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3U99_RS01565	COG2860	membrane
G3U99_RS01570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G3U99_RS01575	COG0083	homoserine kinase activity
G3U99_RS01595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3U99_RS01605	COG0745	RESPONSE REGULATOR receiver
G3U99_RS01615	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G3U99_RS01625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3U99_RS01630	COG3025	triphosphatase activity
G3U99_RS01635	COG1392	Phosphate transport regulator
G3U99_RS01640	COG0306	phosphate transporter
G3U99_RS01645	COG4991	sh3 domain protein
G3U99_RS01655	COG3267	Type II secretory pathway component ExeA
G3U99_RS01655	COG3409	Peptidoglycan-binding domain 1 protein
G3U99_RS01660	COG0617	tRNA 3'-terminal CCA addition
G3U99_RS01665	COG0148	phosphopyruvate hydratase activity
G3U99_RS01675	COG3956	TIGRFAM MazG family protein
G3U99_RS01680	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3U99_RS01685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G3U99_RS01690	COG3850	Histidine kinase
G3U99_RS01690	COG4999	Histidine kinase
G3U99_RS01690	COG3437	response regulator, receiver
G3U99_RS01690	COG2205	protein histidine kinase activity
G3U99_RS01695	COG0736	holo-[acyl-carrier-protein] synthase activity
G3U99_RS01700	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G3U99_RS01705	COG1381	Involved in DNA repair and RecF pathway recombination
G3U99_RS01710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G3U99_RS01725	COG0481	GTPase activity
G3U99_RS01730	COG3086	response to oxidative stress
G3U99_RS01735	COG3026	antisigma factor binding
G3U99_RS01745	COG1595	DNA-templated transcription, initiation
G3U99_RS01750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G3U99_RS01775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3U99_RS01780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3U99_RS01790	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
G3U99_RS01800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G3U99_RS01810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3U99_RS01815	COG2271	Major facilitator Superfamily
G3U99_RS01820	COG0584	glycerophosphoryl diester phosphodiesterase
G3U99_RS01825	COG0440	acetolactate synthase activity
G3U99_RS01830	COG0028	Belongs to the TPP enzyme family
G3U99_RS01835	COG1022	Amp-dependent synthetase and ligase
G3U99_RS01840	COG0583	DNA-binding transcription factor activity
G3U99_RS01860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G3U99_RS01865	COG0473	3-isopropylmalate dehydrogenase activity
G3U99_RS01925	COG3437	response regulator, receiver
G3U99_RS01945	COG1854	S-ribosylhomocysteine lyase activity
G3U99_RS01955	COG2918	glutathione biosynthetic process
G3U99_RS01960	COG0612	Peptidase, M16
G3U99_RS01965	COG1238	metal cluster binding
G3U99_RS01970	COG2130	NADP-dependent
G3U99_RS01975	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
G3U99_RS01980	COG0511	ligase activity, forming carbon-carbon bonds
G3U99_RS01980	COG5016	pyruvate
G3U99_RS01985	COG3630	sodium ion export across plasma membrane
G3U99_RS02035	COG0527	aspartate kinase activity
G3U99_RS02045	COG2137	regulation of response to DNA damage stimulus
G3U99_RS02050	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G3U99_RS02055	COG1546	Belongs to the CinA family
G3U99_RS02085	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G3U99_RS02090	COG0795	lipopolysaccharide-transporting ATPase activity
G3U99_RS02095	COG0795	lipopolysaccharide-transporting ATPase activity
G3U99_RS02105	COG2927	DNA polymerase III (CHI subunit)
G3U99_RS02110	COG0525	valine-tRNA ligase activity
G3U99_RS02120	COG4269	membrane
G3U99_RS02130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3U99_RS02135	COG0564	pseudouridine synthase activity
G3U99_RS02145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G3U99_RS02150	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G3U99_RS02165	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
G3U99_RS02170	COG0251	oxidation-reduction process
G3U99_RS02180	COG0039	L-malate dehydrogenase activity
G3U99_RS02190	COG2358	TRAP transporter, solute receptor (TAXI family
G3U99_RS02200	COG0589	response to stress
G3U99_RS02220	COG2235	arginine
G3U99_RS02225	COG0204	Acyl-transferase
G3U99_RS02235	COG5007	Belongs to the BolA IbaG family
G3U99_RS02245	COG2854	intermembrane phospholipid transfer
G3U99_RS02250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G3U99_RS02255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G3U99_RS02260	COG1127	ABC transporter
G3U99_RS02270	COG0517	IMP dehydrogenase activity
G3U99_RS02270	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G3U99_RS02275	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G3U99_RS02285	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G3U99_RS02290	COG1137	ATPase activity
G3U99_RS02300	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G3U99_RS02305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_RS02310	COG1660	Displays ATPase and GTPase activities
G3U99_RS02315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_RS02320	COG2239	Acts as a magnesium transporter
G3U99_RS02325	COG1410	methionine synthase
G3U99_RS02325	COG0646	methionine synthase
G3U99_RS02385	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3U99_RS02390	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G3U99_RS02540	COG3437	response regulator, receiver
G3U99_RS02545	COG2205	protein histidine kinase activity
G3U99_RS02545	COG0784	Response regulator, receiver
G3U99_RS02545	COG5002	protein histidine kinase activity
G3U99_RS02550	COG0735	belongs to the Fur family
G3U99_RS02560	COG0529	Catalyzes the synthesis of activated sulfate
G3U99_RS02565	COG3273	potassium ion transport
G3U99_RS02565	COG0471	metal ion transport
G3U99_RS02580	COG1648	precorrin-2 dehydrogenase activity
G3U99_RS02580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G3U99_RS02585	COG0737	Belongs to the 5'-nucleotidase family
G3U99_RS02595	COG2153	protein acetylation
G3U99_RS02610	COG0545	Peptidyl-prolyl cis-trans isomerase
G3U99_RS02620	COG0203	ribosomal protein L17
G3U99_RS02635	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G3U99_RS02640	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G3U99_RS02645	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G3U99_RS02650	COG0201	protein transport
G3U99_RS02660	COG1841	ribosomal large subunit assembly
G3U99_RS02675	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G3U99_RS02690	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G3U99_RS02705	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G3U99_RS02720	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G3U99_RS02725	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G3U99_RS02730	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G3U99_RS02745	COG0088	Forms part of the polypeptide exit tunnel
G3U99_RS02755	COG0051	transcription antitermination factor activity, RNA binding
G3U99_RS02760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3U99_RS02765	COG0557	exoribonuclease II activity
G3U99_RS02770	COG0402	S-adenosylhomocysteine deaminase activity
G3U99_RS02775	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
G3U99_RS02785	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G3U99_RS02795	COG1047	Peptidyl-prolyl cis-trans
G3U99_RS02810	COG2249	NAD(P)H dehydrogenase (quinone) activity
G3U99_RS02815	COG0488	(ABC) transporter
G3U99_RS02825	COG0429	hydrolase of the alpha beta-hydrolase fold
G3U99_RS02835	COG3954	Phosphoribulokinase
G3U99_RS02840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3U99_RS02860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G3U99_RS02900	COG1027	Aspartate ammonia-lyase
G3U99_RS02905	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G3U99_RS02910	COG1288	antiporter activity
G3U99_RS02925	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G3U99_RS02930	COG0540	Belongs to the ATCase OTCase family
G3U99_RS02935	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
G3U99_RS02940	COG1438	arginine binding
G3U99_RS02945	COG4232	protein-disulfide reductase activity
G3U99_RS02955	COG2095	MarC family integral membrane protein
G3U99_RS02965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3U99_RS02975	COG0784	Response regulator, receiver
G3U99_RS02975	COG2205	protein histidine kinase activity
G3U99_RS02980	COG2814	Major facilitator Superfamily
G3U99_RS02995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3U99_RS03000	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G3U99_RS03005	COG0511	ligase activity, forming carbon-carbon bonds
G3U99_RS03010	COG0439	Biotin carboxylase
G3U99_RS03015	COG2264	protein methyltransferase activity
G3U99_RS03020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G3U99_RS03025	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G3U99_RS03060	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G3U99_RS03075	COG3706	GGDEF domain
G3U99_RS03080	COG0789	Transcriptional regulator
G3U99_RS03090	COG0151	Belongs to the GarS family
G3U99_RS03105	COG1253	flavin adenine dinucleotide binding
G3U99_RS03115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3U99_RS03120	COG1573	uracil-dna glycosylase
G3U99_RS03125	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G3U99_RS03130	COG1695	Transcriptional regulator
G3U99_RS03135	COG1045	serine acetyltransferase
G3U99_RS03150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3U99_RS03185	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3U99_RS03190	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
G3U99_RS03195	COG1053	succinate dehydrogenase
G3U99_RS03200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G3U99_RS03230	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G3U99_RS03235	COG1609	Transcriptional regulator
G3U99_RS03240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G3U99_RS03250	COG0281	malic enzyme
G3U99_RS03260	COG0626	cystathionine gamma-synthase activity
G3U99_RS03265	COG0527	aspartate kinase activity
G3U99_RS03265	COG0460	homoserine dehydrogenase
G3U99_RS03270	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G3U99_RS03280	COG1494	fructose-1,6-bisphosphatase
G3U99_RS03320	COG0438	transferase activity, transferring glycosyl groups
G3U99_RS03330	COG0463	Glycosyl transferase, family 2
G3U99_RS03360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3U99_RS03370	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
G3U99_RS03375	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
G3U99_RS03410	COG1086	Polysaccharide biosynthesis protein
G3U99_RS03420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G3U99_RS03425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3U99_RS03430	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G3U99_RS03430	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G3U99_RS03435	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G3U99_RS03445	COG0438	transferase activity, transferring glycosyl groups
G3U99_RS03465	COG0859	PFAM glycosyl transferase family 9
G3U99_RS03480	COG1519	Transferase
G3U99_RS03495	COG3642	lipopolysaccharide core region biosynthetic process
G3U99_RS03500	COG0859	PFAM glycosyl transferase family 9
G3U99_RS03505	COG0463	Glycosyl transferase, family 2
G3U99_RS03510	COG0859	PFAM glycosyl transferase family 9
G3U99_RS03515	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G3U99_RS03545	COG2003	Belongs to the UPF0758 family
G3U99_RS03550	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G3U99_RS03555	COG1309	transcriptional regulator
G3U99_RS03560	COG1560	Kdo2-lipid A biosynthetic process
G3U99_RS03565	COG1560	Kdo2-lipid A biosynthetic process
G3U99_RS03570	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G3U99_RS03575	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G3U99_RS03580	COG1561	YicC-like family, N-terminal region
G3U99_RS03585	COG2252	PERMEase
G3U99_RS03595	COG0848	biopolymer transport protein
G3U99_RS03615	COG4206	TonB-dependent receptor
G3U99_RS03615	COG1629	transport
G3U99_RS03625	COG1595	DNA-templated transcription, initiation
G3U99_RS03630	COG0194	GDP metabolic process
G3U99_RS03635	COG1758	RNA polymerase activity
G3U99_RS03640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G3U99_RS03645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3U99_RS03650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G3U99_RS03655	COG1218	3'(2'),5'-bisphosphate nucleotidase
G3U99_RS03660	COG0494	nUDIX hydrolase
G3U99_RS03665	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G3U99_RS03665	COG0316	Belongs to the HesB IscA family
G3U99_RS03675	COG0596	Alpha beta hydrolase
G3U99_RS03685	COG2183	response to ionizing radiation
G3U99_RS03695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3U99_RS03700	COG0745	RESPONSE REGULATOR receiver
G3U99_RS03715	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
G3U99_RS03720	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
G3U99_RS03725	COG3156	type II secretion system protein K
G3U99_RS03730	COG4795	General secretion pathway protein
G3U99_RS03735	COG2165	general secretion pathway protein
G3U99_RS03740	COG2165	general secretion pathway protein
G3U99_RS03745	COG2165	general secretion pathway protein
G3U99_RS03750	COG1459	type II secretion system
G3U99_RS03755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G3U99_RS03765	COG3031	protein transport across the cell outer membrane
G3U99_RS03770	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G3U99_RS03780	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G3U99_RS03790	COG0456	acetyltransferase
G3U99_RS03795	COG1490	D-aminoacyl-tRNA deacylase activity
G3U99_RS03815	COG0174	glutamine synthetase
G3U99_RS03820	COG3852	Histidine kinase
G3U99_RS03825	COG2204	response regulator
G3U99_RS03835	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3U99_RS03875	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G3U99_RS03890	COG0408	coproporphyrinogen oxidase activity
G3U99_RS03900	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G3U99_RS03905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G3U99_RS03910	COG0551	DNA topoisomerase type I activity
G3U99_RS03915	COG2922	Belongs to the Smg family
G3U99_RS03920	COG0758	DNA mediated transformation
G3U99_RS03925	COG0242	peptide deformylase activity
G3U99_RS03935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G3U99_RS03935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G3U99_RS03940	COG0569	domain protein
G3U99_RS03945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G3U99_RS03955	COG1272	protein, Hemolysin III
G3U99_RS03960	COG4326	sporulation control protein
G3U99_RS03970	COG3084	Protein conserved in bacteria
G3U99_RS03980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G3U99_RS03985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3U99_RS03990	COG0204	Acyl-transferase
G3U99_RS04000	COG0606	chelatase, subunit chli
G3U99_RS04010	COG3978	acetolactate synthase activity
G3U99_RS04015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3U99_RS04020	COG0129	dihydroxy-acid dehydratase activity
G3U99_RS04030	COG0604	alcohol dehydrogenase
G3U99_RS04045	COG0425	Belongs to the sulfur carrier protein TusA family
G3U99_RS04055	COG2119	membrane
G3U99_RS04065	COG0751	glycine-tRNA ligase activity
G3U99_RS04070	COG3977	Valine--pyruvate aminotransferase
G3U99_RS04075	COG0071	Belongs to the small heat shock protein (HSP20) family
G3U99_RS04080	COG0187	DNA topoisomerase II activity
G3U99_RS04085	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G3U99_RS04090	COG0592	DNA-directed DNA polymerase activity
G3U99_RS04110	COG1126	abc transporter atp-binding protein
G3U99_RS04130	COG0706	membrane insertase activity
G3U99_RS04135	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G3U99_RS04140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G3U99_RS04145	COG0445	tRNA wobble uridine modification
G3U99_RS04155	COG1192	Involved in chromosome partitioning
G3U99_RS04160	COG1475	DNA binding
G3U99_RS04165	COG3312	ion transport
G3U99_RS04185	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G3U99_RS04190	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G3U99_RS04195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G3U99_RS04200	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G3U99_RS04205	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G3U99_RS04215	COG0765	amino acid transport
G3U99_RS04225	COG2814	Major facilitator Superfamily
G3U99_RS04230	COG0583	DNA-binding transcription factor activity
G3U99_RS04235	COG3706	GGDEF domain
G3U99_RS04250	COG1739	Uncharacterized protein family UPF0029
G3U99_RS04255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G3U99_RS04310	COG2132	Multicopper oxidase
G3U99_RS04325	COG0352	thiamine-phosphate diphosphorylase activity
G3U99_RS04330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G3U99_RS04340	COG2022	thiamine diphosphate biosynthetic process
G3U99_RS04350	COG0006	proline dipeptidase activity
G3U99_RS04350	COG0006	proline dipeptidase activity
G3U99_RS04370	COG1522	sequence-specific DNA binding
G3U99_RS04375	COG5001	Diguanylate cyclase
G3U99_RS04375	COG5002	protein histidine kinase activity
G3U99_RS04380	COG0742	ribosomal rna small subunit methyltransferase
G3U99_RS04395	COG0589	response to stress
G3U99_RS04400	COG1528	Iron-storage protein
G3U99_RS04410	COG2081	HI0933 family
G3U99_RS04440	COG1639	'signal transduction protein
G3U99_RS04450	COG1322	Protein conserved in bacteria
G3U99_RS04455	COG2226	methyltransferase
G3U99_RS04475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G3U99_RS04480	COG0805	protein transport
G3U99_RS04485	COG0084	hydrolase, TatD family'
G3U99_RS04500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3U99_RS04500	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G3U99_RS04530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G3U99_RS04535	COG0583	DNA-binding transcription factor activity
G3U99_RS04540	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G3U99_RS04545	COG2960	long-chain fatty acid transporting porin activity
G3U99_RS04550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3U99_RS04555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_RS04560	COG1309	transcriptional regulator
G3U99_RS04605	COG0747	negative chemotaxis
G3U99_RS04615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3U99_RS04630	COG0745	RESPONSE REGULATOR receiver
G3U99_RS04650	COG0477	Major facilitator Superfamily
G3U99_RS04665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3U99_RS04670	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G3U99_RS04690	COG3220	belongs to the UPF0276 family
G3U99_RS04700	COG0210	DNA helicase
G3U99_RS04715	COG0405	Gamma-glutamyltransferase
G3U99_RS04720	COG1280	lysine exporter protein (LysE YggA)
G3U99_RS04730	COG2962	Rard protein
G3U99_RS04735	COG0514	ATP-dependent DNA helicase (RecQ)
G3U99_RS04745	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G3U99_RS04750	COG0248	Ppx GppA phosphatase
G3U99_RS04760	COG3118	belongs to the thioredoxin family
G3U99_RS04775	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G3U99_RS04835	COG3071	HemY protein
G3U99_RS04840	COG2959	enzyme of heme biosynthesis
G3U99_RS04845	COG1587	Uroporphyrinogen-III synthase
G3U99_RS04855	COG3072	Adenylate cyclase
G3U99_RS04860	COG1965	Belongs to the frataxin family
G3U99_RS04870	COG0019	diaminopimelate decarboxylase activity
G3U99_RS04875	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G3U99_RS04885	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G3U99_RS04890	COG1011	Hydrolase
G3U99_RS04895	COG3287	FIST C domain
G3U99_RS04895	COG2200	EAL domain
G3U99_RS04895	COG2199	diguanylate cyclase activity
G3U99_RS04915	COG0561	phosphatase activity
G3U99_RS04925	COG1280	lysine exporter protein (LysE YggA)
G3U99_RS04930	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G3U99_RS04935	COG0640	Transcriptional regulator
G3U99_RS04940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G3U99_RS04985	COG2095	MarC family integral membrane protein
G3U99_RS04995	COG0742	ribosomal rna small subunit methyltransferase
G3U99_RS05000	COG0552	protein localization to endoplasmic reticulum
G3U99_RS05005	COG2884	Cell division ATP-binding protein ftsE
G3U99_RS05010	COG2177	Part of the ABC transporter FtsEX involved in
G3U99_RS05015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G3U99_RS05020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G3U99_RS05030	COG1580	Controls the rotational direction of flagella during chemotaxis
G3U99_RS05035	COG3161	chorismate lyase activity
G3U99_RS05040	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G3U99_RS05045	COG2937	Belongs to the GPAT DAPAT family
G3U99_RS05050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G3U99_RS05055	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G3U99_RS05065	COG0534	Mate efflux family protein
G3U99_RS05070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3U99_RS05090	COG4206	TonB-dependent receptor
G3U99_RS05100	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G3U99_RS05195	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G3U99_RS05205	COG0137	argininosuccinate synthase activity
G3U99_RS05210	COG0165	Argininosuccinate lyase
G3U99_RS05210	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G3U99_RS05220	COG0251	oxidation-reduction process
G3U99_RS05230	COG0678	peroxiredoxin activity
G3U99_RS05230	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G3U99_RS05240	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G3U99_RS05285	COG0338	D12 class N6 adenine-specific DNA methyltransferase
G3U99_RS05290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G3U99_RS05295	COG0546	phosphoglycolate phosphatase activity
G3U99_RS05300	COG0180	Tryptophanyl-tRNA synthetase
G3U99_RS05305	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G3U99_RS05310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G3U99_RS05315	COG2205	protein histidine kinase activity
G3U99_RS05320	COG0745	RESPONSE REGULATOR receiver
G3U99_RS05325	COG3678	ATP-independent chaperone mediated protein folding
G3U99_RS05335	COG0205	6-phosphofructokinase activity
G3U99_RS05340	COG1285	pathogenesis
G3U99_RS05350	COG1509	lysine 2,3-aminomutase activity
G3U99_RS05355	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G3U99_RS05360	COG1575	Belongs to the MenA family. Type 1 subfamily
G3U99_RS05365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G3U99_RS05370	COG0534	Mate efflux family protein
G3U99_RS05375	COG0149	triose-phosphate isomerase activity
G3U99_RS05390	COG1072	(Pantothenic acid kinase))
G3U99_RS05415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3U99_RS05425	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G3U99_RS05430	COG0250	Participates in transcription elongation, termination and antitermination
G3U99_RS05445	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G3U99_RS05455	COG0085	RNA polymerase activity
G3U99_RS05465	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
G3U99_RS05470	COG2816	NAD+ diphosphatase activity
G3U99_RS05490	COG4942	peptidase
G3U99_RS05495	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G3U99_RS05505	COG0840	transmembrane signaling receptor activity
G3U99_RS05510	COG0490	domain, Protein
G3U99_RS05510	COG0471	metal ion transport
G3U99_RS05515	COG0688	phosphatidylethanolamine metabolic process
G3U99_RS05520	COG1162	GTPase activity
G3U99_RS05525	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G3U99_RS05580	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G3U99_RS05585	COG0802	atpase or kinase
G3U99_RS05595	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G3U99_RS05610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G3U99_RS05615	COG0330	HflC and HflK could
G3U99_RS05620	COG0330	HflC and HflK could
G3U99_RS05625	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
G3U99_RS05640	COG0545	Peptidyl-prolyl cis-trans isomerase
G3U99_RS05645	COG2964	Protein conserved in bacteria
G3U99_RS05655	COG2923	Belongs to the DsrF TusC family
G3U99_RS05660	COG2168	tRNA wobble position uridine thiolation
G3U99_RS05670	COG0049	tRNA binding
G3U99_RS05675	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G3U99_RS05680	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G3U99_RS05685	COG2906	2 iron, 2 sulfur cluster binding
G3U99_RS05695	COG0360	Binds together with S18 to 16S ribosomal RNA
G3U99_RS05715	COG0305	Participates in initiation and elongation during chromosome replication
G3U99_RS05720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G3U99_RS05725	COG0432	Pfam Uncharacterised protein family UPF0047
G3U99_RS05750	COG1136	(ABC) transporter
G3U99_RS05765	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
G3U99_RS05775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3U99_RS05780	COG0729	surface antigen
G3U99_RS05790	COG2105	PFAM AIG2 family protein
G3U99_RS05795	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G3U99_RS05805	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G3U99_RS05810	COG0163	prenyltransferase activity
G3U99_RS05815	COG4143	(ABC) transporter
G3U99_RS05820	COG1178	ABC-type Fe3 transport system permease component
G3U99_RS05825	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
G3U99_RS05830	COG3028	Belongs to the UPF0307 family
G3U99_RS05835	COG0312	modulator of DNA gyrase
G3U99_RS05840	COG0527	aspartate kinase activity
G3U99_RS05845	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G3U99_RS05855	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G3U99_RS05870	COG0629	single-stranded DNA binding
G3U99_RS05875	COG2199	diguanylate cyclase activity
G3U99_RS05875	COG2200	EAL domain
G3U99_RS05900	COG3409	Peptidoglycan-binding domain 1 protein
G3U99_RS05900	COG3267	Type II secretory pathway component ExeA
G3U99_RS05910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G3U99_RS05915	COG1459	type II secretion system
G3U99_RS05960	COG1077	Cell shape determining protein MreB Mrl
G3U99_RS05965	COG1792	Involved in formation and maintenance of cell shape
G3U99_RS05970	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G3U99_RS05975	COG0424	maF-like protein
G3U99_RS05980	COG1530	ribonuclease E activity
G3U99_RS05985	COG3164	Protein of unknown function
G3U99_RS05990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3U99_RS05995	COG0312	modulator of DNA gyrase
G3U99_RS06050	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G3U99_RS06060	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G3U99_RS06065	COG2066	Belongs to the glutaminase family
G3U99_RS06070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G3U99_RS06075	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G3U99_RS06200	COG0762	integral membrane protein
G3U99_RS06205	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G3U99_RS06210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G3U99_RS06225	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G3U99_RS06230	COG1678	Uncharacterized ACR, COG1678
G3U99_RS06235	COG0189	ligase activity
G3U99_RS06240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G3U99_RS06245	COG2356	endonuclease I
G3U99_RS06250	COG3091	SprT-like family
G3U99_RS06260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G3U99_RS06270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G3U99_RS06280	COG0191	fructose-bisphosphate aldolase activity
G3U99_RS06285	COG0668	transmembrane transport
G3U99_RS06290	COG0442	prolyl-tRNA aminoacylation
G3U99_RS06300	COG0583	DNA-binding transcription factor activity
G3U99_RS06310	COG3706	GGDEF domain
G3U99_RS06320	COG0469	pyruvate kinase activity
G3U99_RS06325	COG1349	DNA-binding transcription factor activity
G3U99_RS06330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G3U99_RS06335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3U99_RS06340	COG3722	fumarate hydratase activity
G3U99_RS06350	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_RS06350	COG2213	PTS system mannitol-specific
G3U99_RS06355	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3U99_RS06365	COG0142	geranyltranstransferase activity
G3U99_RS06370	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G3U99_RS06380	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G3U99_RS06385	COG2966	Psort location CytoplasmicMembrane, score
G3U99_RS06390	COG3610	response to peptide
G3U99_RS06400	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G3U99_RS06410	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G3U99_RS06420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3U99_RS06430	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G3U99_RS06445	COG0358	DNA primase activity
G3U99_RS06450	COG1610	YqeY-like protein
G3U99_RS06455	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G3U99_RS06460	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G3U99_RS06470	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G3U99_RS06475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G3U99_RS06480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G3U99_RS06490	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G3U99_RS06495	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G3U99_RS06505	COG0585	pseudouridine synthase activity
G3U99_RS06510	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G3U99_RS06525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G3U99_RS06530	COG4536	flavin adenine dinucleotide binding
G3U99_RS06535	COG4137	Cytochrome C assembly protein
G3U99_RS06540	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G3U99_RS06545	COG0228	four-way junction DNA binding
G3U99_RS06555	COG0336	Belongs to the RNA methyltransferase TrmD family
G3U99_RS06565	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G3U99_RS06570	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
G3U99_RS06575	COG0237	dephospho-CoA kinase activity
G3U99_RS06585	COG1459	type II secretion system
G3U99_RS06590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G3U99_RS06595	COG4969	Belongs to the N-Me-Phe pilin family
G3U99_RS06600	COG0157	Belongs to the NadC ModD family
G3U99_RS06605	COG3023	N-Acetylmuramoyl-L-alanine amidase
G3U99_RS06615	COG4974	Belongs to the 'phage' integrase family
G3U99_RS06620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3U99_RS06625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G3U99_RS06630	COG2186	Transcriptional regulator
G3U99_RS06635	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G3U99_RS06640	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3U99_RS06645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G3U99_RS06660	COG0288	reversible hydration of carbon dioxide
G3U99_RS06665	COG0659	secondary active sulfate transmembrane transporter activity
G3U99_RS06670	COG1131	(ABC) transporter
G3U99_RS06675	COG0842	Transport permease protein
G3U99_RS06685	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G3U99_RS06690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G3U99_RS06705	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G3U99_RS06715	COG1643	Atp-dependent helicase
G3U99_RS06720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G3U99_RS06725	COG1752	Esterase of the alpha-beta hydrolase superfamily
G3U99_RS06730	COG1049	propionate catabolic process, 2-methylcitrate cycle
G3U99_RS06745	COG0004	ammonium transporteR
G3U99_RS06750	COG1840	ABC-type Fe3 transport system, periplasmic component
G3U99_RS06760	COG3842	ATPase activity
G3U99_RS06765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3U99_RS06780	COG2971	BadF BadG BcrA BcrD
G3U99_RS06790	COG4608	Belongs to the ABC transporter superfamily
G3U99_RS06795	COG0444	Belongs to the ABC transporter superfamily
G3U99_RS06810	COG0747	negative chemotaxis
G3U99_RS06815	COG0784	Response regulator, receiver
G3U99_RS06815	COG2205	protein histidine kinase activity
G3U99_RS06820	COG2813	Specifically methylates the guanine in position
G3U99_RS06825	COG0628	permease
G3U99_RS06850	COG0739	heme binding
G3U99_RS06855	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G3U99_RS06860	COG2239	Acts as a magnesium transporter
G3U99_RS06865	COG2027	D-alanyl-D-alanine carboxypeptidase
G3U99_RS06870	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
G3U99_RS06875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3U99_RS06880	COG1534	Rna-binding protein
G3U99_RS06885	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G3U99_RS06890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G3U99_RS06895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G3U99_RS06900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3U99_RS06925	COG0513	Belongs to the DEAD box helicase family
G3U99_RS06945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G3U99_RS06950	COG0826	peptidase U32
G3U99_RS06955	COG0826	peptidase U32
G3U99_RS06965	COG3154	lipid carrier protein
G3U99_RS06970	COG3153	acetyltransferase
G3U99_RS06975	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G3U99_RS06990	COG0779	Required for maturation of 30S ribosomal subunits
G3U99_RS06995	COG0195	Participates in both transcription termination and antitermination
G3U99_RS07020	COG0493	'glutamate synthase
G3U99_RS07025	COG0069	glutamate synthase activity
G3U99_RS07025	COG0070	glutamate synthase
G3U99_RS07025	COG0067	glutamate synthase
G3U99_RS07035	COG0067	glutamate synthase
G3U99_RS07035	COG0070	glutamate synthase
G3U99_RS07035	COG0069	glutamate synthase activity
G3U99_RS07040	COG1242	4 iron, 4 sulfur cluster binding
G3U99_RS07045	COG5001	Diguanylate cyclase
G3U99_RS07045	COG3706	GGDEF domain
G3U99_RS07045	COG4251	negative regulation of phosphorylation
G3U99_RS07045	COG2203	Gaf domain
G3U99_RS07050	COG0784	Response regulator, receiver
G3U99_RS07050	COG5002	protein histidine kinase activity
G3U99_RS07050	COG2198	Histidine kinase
G3U99_RS07060	COG1538	Outer membrane efflux protein
G3U99_RS07065	COG0494	nUDIX hydrolase
G3U99_RS07070	COG3151	Protein conserved in bacteria
G3U99_RS07080	COG3150	esterase
G3U99_RS07095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3U99_RS07100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G3U99_RS07105	COG3105	Protein conserved in bacteria
G3U99_RS07110	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G3U99_RS07125	COG0723	plastoquinol--plastocyanin reductase activity
G3U99_RS07130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G3U99_RS07135	COG2857	Cytochrome c1
G3U99_RS07140	COG0625	glutathione transferase activity
G3U99_RS07145	COG2969	positive regulation of protein catabolic process
G3U99_RS07155	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G3U99_RS07165	COG3107	peptidoglycan biosynthetic process
G3U99_RS07170	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G3U99_RS07185	COG3116	cell division
G3U99_RS07190	COG0768	penicillin binding
G3U99_RS07195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3U99_RS07200	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G3U99_RS07210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G3U99_RS07215	COG0772	Belongs to the SEDS family
G3U99_RS07230	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G3U99_RS07235	COG0849	cell division
G3U99_RS07240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G3U99_RS07245	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G3U99_RS07250	COG0653	protein targeting
G3U99_RS07255	COG0494	nUDIX hydrolase
G3U99_RS07265	COG0505	Belongs to the CarA family
G3U99_RS07270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G3U99_RS07275	COG0730	response to heat
G3U99_RS07280	COG0583	DNA-binding transcription factor activity
G3U99_RS07285	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
G3U99_RS07295	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G3U99_RS07310	COG1115	amino acid carrier protein
G3U99_RS07315	COG3022	response to hydroperoxide
G3U99_RS07325	COG0084	hydrolase, TatD family'
G3U99_RS07330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G3U99_RS07345	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G3U99_RS07350	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G3U99_RS07355	COG0813	purine-nucleoside phosphorylase activity
G3U99_RS07365	COG0560	Phosphoserine phosphatase
G3U99_RS07375	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G3U99_RS07380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G3U99_RS07385	COG0693	protein deglycase activity
G3U99_RS07390	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3U99_RS07405	COG1595	DNA-templated transcription, initiation
G3U99_RS07420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G3U99_RS07430	COG2813	Specifically methylates the guanine in position
G3U99_RS07435	COG0271	Belongs to the BolA IbaG family
G3U99_RS07440	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G3U99_RS07445	COG1805	sodium ion transport
G3U99_RS07460	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G3U99_RS07465	COG2871	sodium ion transport
G3U99_RS07470	COG1477	protein flavinylation
G3U99_RS07485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G3U99_RS07490	COG0514	ATP-dependent DNA helicase (RecQ)
G3U99_RS07495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G3U99_RS07510	COG0733	neurotransmitter:sodium symporter activity
G3U99_RS07520	COG0189	ligase activity
G3U99_RS07525	COG0189	ligase activity
G3U99_RS07525	COG4067	protein conserved in archaea
G3U99_RS07530	COG2195	Cleaves the N-terminal amino acid of tripeptides
G3U99_RS07535	COG2252	PERMEase
G3U99_RS07540	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
G3U99_RS07555	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G3U99_RS07560	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G3U99_RS07565	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G3U99_RS07570	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3U99_RS07570	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3U99_RS07590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G3U99_RS07595	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G3U99_RS07600	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G3U99_RS07615	COG0024	Methionine aminopeptidase
G3U99_RS07620	COG0052	Belongs to the universal ribosomal protein uS2 family
G3U99_RS07625	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G3U99_RS07630	COG0528	UMP kinase activity
G3U99_RS07635	COG0233	cytoplasmic translational termination
G3U99_RS07640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G3U99_RS07645	COG0575	Belongs to the CDS family
G3U99_RS07655	COG0750	zinc metalloprotease
G3U99_RS07660	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G3U99_RS07665	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
G3U99_RS07670	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G3U99_RS07675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G3U99_RS07690	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G3U99_RS07695	COG0587	DNA-directed DNA polymerase activity
G3U99_RS07700	COG0825	malonyl-CoA metabolic process
G3U99_RS07715	COG0347	Belongs to the P(II) protein family
G3U99_RS07720	COG3021	interspecies interaction between organisms
G3U99_RS07730	COG0741	lytic transglycosylase activity
G3U99_RS07730	COG1388	LysM domain
G3U99_RS07740	COG2226	methyltransferase
G3U99_RS07745	COG0328	RNA-DNA hybrid ribonuclease activity
G3U99_RS07760	COG1960	acyl-CoA dehydrogenase activity
G3U99_RS07765	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G3U99_RS07770	COG0121	glutamine amidotransferase
G3U99_RS07780	COG1720	tRNA m6t6A37 methyltransferase activity
G3U99_RS07795	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
G3U99_RS07805	COG1464	Belongs to the NlpA lipoprotein family
G3U99_RS07810	COG2011	ABC-type metal ion transport system permease component
G3U99_RS07815	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G3U99_RS07820	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G3U99_RS07830	COG1609	Transcriptional regulator
G3U99_RS07835	COG1263	PTS System
G3U99_RS07835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G3U99_RS07840	COG0366	Alpha amylase catalytic
G3U99_RS07865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_RS07870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3U99_RS07880	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G3U99_RS07895	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G3U99_RS07905	COG2921	Belongs to the UPF0250 family
G3U99_RS07910	COG1686	Belongs to the peptidase S11 family
G3U99_RS07915	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G3U99_RS07920	COG0772	Belongs to the SEDS family
G3U99_RS07925	COG0768	penicillin binding
G3U99_RS07930	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G3U99_RS07935	COG0799	negative regulation of ribosome biogenesis
G3U99_RS07940	COG1466	dna polymerase III delta subunit
G3U99_RS07945	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
G3U99_RS07950	COG0495	leucyl-tRNA aminoacylation
G3U99_RS07955	COG2888	peptidyl-tyrosine sulfation
G3U99_RS07960	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G3U99_RS07965	COG4535	Mg2 and Co2 transporter CorC
G3U99_RS07970	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G3U99_RS07975	COG1702	phosphate starvation-inducible protein PhoH
G3U99_RS07985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G3U99_RS07990	COG2190	(PTS) system
G3U99_RS07995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G3U99_RS08000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_RS08005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G3U99_RS08010	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
G3U99_RS08015	COG3115	cell septum assembly
G3U99_RS08040	COG0330	HflC and HflK could
G3U99_RS08045	COG3118	belongs to the thioredoxin family
G3U99_RS08055	COG0300	oxidoreductase activity
G3U99_RS08060	COG1090	epimerase
G3U99_RS08085	COG0622	Phosphoesterase
G3U99_RS08105	COG3710	Transcriptional regulator
G3U99_RS08110	COG0326	Molecular chaperone. Has ATPase activity
G3U99_RS08120	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G3U99_RS08140	COG2608	mercury ion transmembrane transporter activity
G3U99_RS08140	COG2217	Heavy metal translocating P-type atpase
G3U99_RS08180	COG2194	sulfuric ester hydrolase activity
G3U99_RS08190	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G3U99_RS08230	COG2747	anti-sigma28 factor FlgM
G3U99_RS08240	COG0784	Response regulator, receiver
G3U99_RS08240	COG0835	chemotaxis
G3U99_RS08245	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G3U99_RS08250	COG1815	bacterial-type flagellum-dependent cell motility
G3U99_RS08270	COG4787	bacterial-type flagellum-dependent cell motility
G3U99_RS08280	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G3U99_RS08285	COG1706	bacterial-type flagellum-dependent cell motility
G3U99_RS08290	COG1705	Flagellar rod assembly protein muramidase FlgJ
G3U99_RS08290	COG3951	Flagellar rod assembly protein muramidase FlgJ
G3U99_RS08300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G3U99_RS08305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G3U99_RS08420	COG0012	GTP binding
G3U99_RS08430	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G3U99_RS08455	COG2890	protein-(glutamine-N5) methyltransferase activity
G3U99_RS08465	COG2912	Transglutaminase-like superfamily
G3U99_RS08470	COG2877	3-deoxy-8-phosphooctulonate synthase activity
G3U99_RS08480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G3U99_RS08485	COG2233	PERMEase
G3U99_RS08505	COG1393	Belongs to the ArsC family
G3U99_RS08510	COG4783	chaperone-mediated protein folding
G3U99_RS08530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G3U99_RS08535	COG2716	regulation of RNA biosynthetic process
G3U99_RS08550	COG2056	Na+-H+ antiporter family
G3U99_RS08570	COG0346	lactoylglutathione lyase activity
G3U99_RS08575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G3U99_RS08590	COG4658	electron transport chain
G3U99_RS08595	COG4656	Part of a membrane complex involved in electron transport
G3U99_RS08605	COG4657	Part of a membrane complex involved in electron transport
G3U99_RS08610	COG1388	LysM domain
G3U99_RS08610	COG0741	lytic transglycosylase activity
G3U99_RS08630	COG1815	bacterial-type flagellum-dependent cell motility
G3U99_RS08635	COG1558	bacterial-type flagellum-dependent cell motility
G3U99_RS08645	COG1749	Flagellar hook protein flgE
G3U99_RS08650	COG4787	bacterial-type flagellum-dependent cell motility
G3U99_RS08655	COG4786	Flagellar basal body rod
G3U99_RS08660	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G3U99_RS08665	COG1706	bacterial-type flagellum-dependent cell motility
G3U99_RS08695	COG1360	Flagellar Motor Protein
G3U99_RS08700	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G3U99_RS08705	COG1191	sigma factor activity
G3U99_RS08710	COG1580	Controls the rotational direction of flagella during chemotaxis
G3U99_RS08725	COG1516	flagellar protein fliS
G3U99_RS08730	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G3U99_RS08735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G3U99_RS08750	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G3U99_RS08760	COG1987	bacterial-type flagellum assembly
G3U99_RS08780	COG2885	chlorophyll binding
G3U99_RS08825	COG0739	heme binding
G3U99_RS08845	COG0556	nucleotide-excision repair
G3U99_RS08855	COG2198	Histidine kinase
G3U99_RS08860	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G3U99_RS08865	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G3U99_RS08870	COG0521	Mo-molybdopterin cofactor biosynthetic process
G3U99_RS08880	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G3U99_RS08885	COG0314	molybdopterin synthase activity
G3U99_RS08890	COG3706	GGDEF domain
G3U99_RS08900	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G3U99_RS08900	COG0617	tRNA 3'-terminal CCA addition
G3U99_RS08900	COG0517	IMP dehydrogenase activity
G3U99_RS08930	COG0745	RESPONSE REGULATOR receiver
G3U99_RS08940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3U99_RS08940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3U99_RS08945	COG0489	protein tyrosine kinase activity
G3U99_RS08950	COG0572	uridine kinase
G3U99_RS08955	COG2982	Protein involved in outer membrane biogenesis
G3U99_RS09005	COG0110	maltose O-acetyltransferase activity
G3U99_RS09010	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
G3U99_RS09020	COG0302	gtp cyclohydrolase
G3U99_RS09025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G3U99_RS09030	COG0302	gtp cyclohydrolase
G3U99_RS09030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G3U99_RS09035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G3U99_RS09055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G3U99_RS09060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3U99_RS09070	COG1881	PFAM PEBP family protein
G3U99_RS09080	COG0123	including yeast histone deacetylase and acetoin utilization protein
G3U99_RS09125	COG0840	transmembrane signaling receptor activity
G3U99_RS09145	COG3083	sulfuric ester hydrolase activity
G3U99_RS09150	COG3082	Protein of unknown function (DUF1414)
G3U99_RS09175	COG1757	Na H antiporter
G3U99_RS09180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G3U99_RS09185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3U99_RS09190	COG2095	MarC family integral membrane protein
G3U99_RS09195	COG1012	belongs to the aldehyde dehydrogenase family
G3U99_RS09195	COG1454	alcohol dehydrogenase
G3U99_RS09200	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G3U99_RS09205	COG2894	cell division
G3U99_RS09210	COG0850	regulation of cytokinetic process
G3U99_RS09215	COG3100	YcgL domain-containing protein
G3U99_RS09220	COG2951	lytic endotransglycosylase activity
G3U99_RS09225	COG0583	DNA-binding transcription factor activity
G3U99_RS09230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G3U99_RS09245	COG2983	Belongs to the UPF0260 family
G3U99_RS09250	COG0668	transmembrane transport
G3U99_RS09270	COG1785	Belongs to the alkaline phosphatase family
G3U99_RS09285	COG2226	methyltransferase
G3U99_RS09290	COG0840	transmembrane signaling receptor activity
G3U99_RS09305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3U99_RS09315	COG3139	Protein of unknown function (DUF1315)
G3U99_RS09320	COG3012	SEC-C Motif Domain Protein
G3U99_RS09325	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G3U99_RS09335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G3U99_RS09340	COG0215	cysteine-tRNA ligase activity
G3U99_RS09345	COG1435	thymidine kinase activity
G3U99_RS09350	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G3U99_RS09355	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G3U99_RS09380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G3U99_RS09385	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G3U99_RS09410	COG3070	regulator of competence-specific genes
G3U99_RS09425	COG0745	RESPONSE REGULATOR receiver
G3U99_RS09430	COG1434	Gram-negative-bacterium-type cell wall biogenesis
G3U99_RS09435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3U99_RS09445	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
G3U99_RS09450	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
G3U99_RS09480	COG4067	protein conserved in archaea
G3U99_RS09480	COG0189	ligase activity
G3U99_RS09485	COG0500	methyltransferase
G3U99_RS09495	COG1801	Protein of unknown function DUF72
G3U99_RS09505	COG1187	pseudouridine synthase activity
G3U99_RS09515	COG1278	Cold shock
G3U99_RS09525	COG0542	response to heat
G3U99_RS09550	COG2116	formate transmembrane transporter activity
G3U99_RS09560	COG0390	transport system, permease component
G3U99_RS09565	COG4459	periplasmic nitrate reductase
G3U99_RS09570	COG3005	denitrification pathway
G3U99_RS09575	COG0243	molybdopterin cofactor binding
G3U99_RS09585	COG4221	oxidoreductase activity
G3U99_RS09605	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G3U99_RS09610	COG0840	transmembrane signaling receptor activity
G3U99_RS09615	COG0632	four-way junction helicase activity
G3U99_RS09620	COG2255	four-way junction helicase activity
G3U99_RS09625	COG1271	oxidase subunit
G3U99_RS09630	COG1294	oxidase, subunit
G3U99_RS09635	COG4890	Cyd operon protein YbgT
G3U99_RS09645	COG0824	Thioesterase
G3U99_RS09650	COG0811	peptide transport
G3U99_RS09670	COG2885	chlorophyll binding
G3U99_RS09675	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
G3U99_RS09680	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G3U99_RS09685	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G3U99_RS09700	COG5640	endopeptidase activity
G3U99_RS09715	COG5002	protein histidine kinase activity
G3U99_RS09715	COG0784	Response regulator, receiver
G3U99_RS09730	COG0556	nucleotide-excision repair
G3U99_RS09745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G3U99_RS09760	COG1940	carbohydrate kinase activity
G3U99_RS09775	COG3850	Histidine kinase
G3U99_RS09775	COG5002	protein histidine kinase activity
G3U99_RS09780	COG0745	RESPONSE REGULATOR receiver
G3U99_RS09785	COG0463	Glycosyl transferase, family 2
G3U99_RS09790	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G3U99_RS09805	COG1960	acyl-CoA dehydrogenase activity
G3U99_RS09810	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G3U99_RS09815	COG0708	Exodeoxyribonuclease III
G3U99_RS09820	COG0840	transmembrane signaling receptor activity
G3U99_RS09825	COG2850	peptidyl-arginine hydroxylation
G3U99_RS09840	COG0730	response to heat
G3U99_RS09845	COG1199	ATP-dependent helicase activity
G3U99_RS09855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3U99_RS09865	COG0156	8-amino-7-oxononanoate synthase activity
G3U99_RS09870	COG2226	methyltransferase
G3U99_RS09870	COG1073	alpha beta
G3U99_RS09875	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G3U99_RS09895	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_RS09910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3U99_RS09920	COG2268	Band 7 protein
G3U99_RS09930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G3U99_RS09940	COG0482	sulfurtransferase activity
G3U99_RS09950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_RS09960	COG1757	Na H antiporter
G3U99_RS09970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G3U99_RS09980	COG0131	Imidazoleglycerol-phosphate dehydratase
G3U99_RS09980	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G3U99_RS09985	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G3U99_RS09990	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G3U99_RS10000	COG0140	phosphoribosyl-ATP diphosphatase activity
G3U99_RS10000	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G3U99_RS10005	COG0217	transcriptional regulatory protein
G3U99_RS10015	COG1227	inorganic diphosphatase activity
G3U99_RS10030	COG4172	Belongs to the ABC transporter superfamily
G3U99_RS10040	COG4171	peptide transport system, permease
G3U99_RS10055	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G3U99_RS10060	COG1842	Phage shock protein A
G3U99_RS10070	COG1983	PspC domain protein
G3U99_RS10090	COG2818	Glycosylase
G3U99_RS10095	COG5380	lipid catabolic process
G3U99_RS10100	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G3U99_RS10105	COG0626	cystathionine gamma-synthase activity
G3U99_RS10115	COG0733	neurotransmitter:sodium symporter activity
G3U99_RS10120	COG0564	pseudouridine synthase activity
G3U99_RS10125	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G3U99_RS10130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G3U99_RS10135	COG4136	ATPase activity
G3U99_RS10140	COG4135	transport system, permease component
G3U99_RS10145	COG4134	Bacterial extracellular solute-binding protein
G3U99_RS10155	COG3313	Fe-S protein
G3U99_RS10170	COG2350	Protein conserved in bacteria
G3U99_RS10215	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G3U99_RS10230	COG0417	DNA replication proofreading
G3U99_RS10245	COG2197	response regulator
G3U99_RS10250	COG0322	excinuclease ABC activity
G3U99_RS10280	COG1902	pentaerythritol trinitrate reductase activity
G3U99_RS10290	COG2133	pyrroloquinoline quinone binding
G3U99_RS10315	COG3706	GGDEF domain
G3U99_RS10325	COG0072	phenylalanine-tRNA ligase activity
G3U99_RS10325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3U99_RS10375	COG1741	Belongs to the pirin family
G3U99_RS10380	COG1335	isochorismatase
G3U99_RS10390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G3U99_RS10390	COG1263	PTS System
G3U99_RS10405	COG1621	beta-fructofuranosidase activity
G3U99_RS10425	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G3U99_RS10430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_RS10450	COG0583	DNA-binding transcription factor activity
G3U99_RS10460	COG0277	FAD linked oxidase domain protein
G3U99_RS10470	COG4211	Belongs to the binding-protein-dependent transport system permease family
G3U99_RS10485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_RS10490	COG3962	Belongs to the TPP enzyme family
G3U99_RS10530	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G3U99_RS10535	COG0183	Belongs to the thiolase family
G3U99_RS10550	COG0583	DNA-binding transcription factor activity
G3U99_RS10555	COG0477	Major facilitator Superfamily
G3U99_RS10555	COG2814	Major facilitator Superfamily
G3U99_RS10565	COG3962	Belongs to the TPP enzyme family
G3U99_RS10570	COG0673	inositol 2-dehydrogenase activity
G3U99_RS10575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_RS10600	COG3718	enzyme involved in inositol metabolism
G3U99_RS10605	COG0673	inositol 2-dehydrogenase activity
G3U99_RS10615	COG1216	Glycosyl transferase, family 2
G3U99_RS10630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G3U99_RS10640	COG3437	response regulator, receiver
G3U99_RS10645	COG0488	(ABC) transporter
G3U99_RS10650	COG2205	protein histidine kinase activity
G3U99_RS10650	COG0784	Response regulator, receiver
G3U99_RS10660	COG1858	cytochrome C peroxidase
G3U99_RS10680	COG0745	RESPONSE REGULATOR receiver
G3U99_RS10685	COG0642	Histidine kinase
G3U99_RS10695	COG1609	Transcriptional regulator
G3U99_RS10700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3U99_RS10715	COG1609	Transcriptional regulator
G3U99_RS10725	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G3U99_RS10765	COG0583	DNA-binding transcription factor activity
G3U99_RS10775	COG1012	belongs to the aldehyde dehydrogenase family
G3U99_RS10785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3U99_RS10810	COG0583	DNA-binding transcription factor activity
G3U99_RS10815	COG0352	thiamine-phosphate diphosphorylase activity
G3U99_RS10820	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G3U99_RS10825	COG1280	lysine exporter protein (LysE YggA)
G3U99_RS10830	COG1115	amino acid carrier protein
G3U99_RS10845	COG1987	bacterial-type flagellum assembly
G3U99_RS10855	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G3U99_RS10860	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G3U99_RS10865	COG4786	Flagellar basal body rod
G3U99_RS10870	COG4786	Flagellar basal body rod
G3U99_RS10880	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G3U99_RS10885	COG1706	bacterial-type flagellum-dependent cell motility
G3U99_RS10900	COG1677	Flagellar hook-basal body complex protein FliE
G3U99_RS10905	COG1766	The M ring may be actively involved in energy transduction
G3U99_RS10935	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G3U99_RS10960	COG1191	sigma factor activity
G3U99_RS11070	COG3300	MHYT domain
G3U99_RS11070	COG5001	Diguanylate cyclase
G3U99_RS11130	COG0778	Nitroreductase
G3U99_RS11135	COG4580	involved in the transport of maltose and maltodextrins
G3U99_RS11155	COG0242	peptide deformylase activity
G3U99_RS11205	COG0307	riboflavin synthase, alpha
G3U99_RS11240	COG4221	oxidoreductase activity
G3U99_RS11275	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G3U99_RS11280	COG0583	DNA-binding transcription factor activity
G3U99_RS11310	COG0463	Glycosyl transferase, family 2
G3U99_RS11330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_RS11335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3U99_RS11360	COG2205	protein histidine kinase activity
G3U99_RS11375	COG1061	Type III restriction enzyme res subunit
G3U99_RS11385	COG2814	Major facilitator Superfamily
G3U99_RS11395	COG0702	epimerase
G3U99_RS11400	COG0534	Mate efflux family protein
G3U99_RS11405	COG1136	(ABC) transporter
G3U99_RS11455	COG0019	diaminopimelate decarboxylase activity
G3U99_RS11480	COG0633	Ferredoxin
G3U99_RS11485	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G3U99_RS11490	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G3U99_RS11500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3U99_RS11510	COG0840	transmembrane signaling receptor activity
G3U99_RS11515	COG1328	CTP reductase activity
G3U99_RS11520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G3U99_RS11565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3U99_RS11570	COG0745	RESPONSE REGULATOR receiver
G3U99_RS11575	COG2205	protein histidine kinase activity
G3U99_RS11590	COG0811	peptide transport
G3U99_RS11595	COG0811	peptide transport
G3U99_RS11600	COG0848	biopolymer transport protein
G3U99_RS11620	COG3290	protein histidine kinase activity
G3U99_RS11625	COG4565	transcriptional regulatory protein
G3U99_RS11655	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3U99_RS11665	COG2116	formate transmembrane transporter activity
G3U99_RS11685	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G3U99_RS11690	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G3U99_RS11705	COG0583	DNA-binding transcription factor activity
G3U99_RS11715	COG0745	RESPONSE REGULATOR receiver
G3U99_RS11725	COG3713	MltA-interacting MipA family protein
G3U99_RS11735	COG2186	Transcriptional regulator
G3U99_RS11745	COG1288	antiporter activity
G3U99_RS11755	COG2814	Major facilitator Superfamily
G3U99_RS11765	COG3835	regulator
G3U99_RS11770	COG1929	Belongs to the glycerate kinase type-1 family
G3U99_RS11775	COG2977	Belongs to the P-Pant transferase superfamily
G3U99_RS11780	COG1120	ATPase activity
G3U99_RS11785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3U99_RS11795	COG4615	Cyclic peptide transporter
G3U99_RS11815	COG4774	siderophore transport
G3U99_RS11855	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3U99_RS11865	COG0297	glycogen (starch) synthase activity
G3U99_RS11900	COG0438	transferase activity, transferring glycosyl groups
G3U99_RS11910	COG2204	response regulator
G3U99_RS11955	COG0534	Mate efflux family protein
G3U99_RS11960	COG0307	riboflavin synthase, alpha
G3U99_RS11970	COG3001	Fructosamine kinase
G3U99_RS11980	COG0791	NLP P60 protein
G3U99_RS11985	COG0840	transmembrane signaling receptor activity
G3U99_RS12000	COG1940	carbohydrate kinase activity
G3U99_RS12015	COG0303	'Molybdopterin
G3U99_RS12020	COG0746	molybdenum cofactor guanylyltransferase activity
G3U99_RS12025	COG3842	ATPase activity
G3U99_RS12045	COG3852	Histidine kinase
G3U99_RS12060	COG1595	DNA-templated transcription, initiation
G3U99_RS12070	COG0488	(ABC) transporter
G3U99_RS12085	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_RS12095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_RS12100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3U99_RS12105	COG3710	Transcriptional regulator
G3U99_RS12110	COG0069	glutamate synthase activity
G3U99_RS12130	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G3U99_RS12135	COG0583	DNA-binding transcription factor activity
G3U99_RS12145	COG0583	DNA-binding transcription factor activity
G3U99_RS12170	COG3038	cytochrome b561
G3U99_RS12180	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G3U99_RS12210	COG3383	formate dehydrogenase (NAD+) activity
G3U99_RS12210	COG0243	molybdopterin cofactor binding
G3U99_RS12215	COG0437	4 iron, 4 sulfur cluster binding
G3U99_RS12230	COG0004	ammonium transporteR
G3U99_RS12235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G3U99_RS12240	COG2199	diguanylate cyclase activity
G3U99_RS12245	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G3U99_RS12250	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G3U99_RS12255	COG1177	transmembrane transport
G3U99_RS12265	COG3842	ATPase activity
G3U99_RS12290	COG0589	response to stress
G3U99_RS12295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3U99_RS12310	COG2217	Heavy metal translocating P-type atpase
G3U99_RS12320	COG2010	Cytochrome c
G3U99_RS12335	COG3278	Belongs to the heme-copper respiratory oxidase family
G3U99_RS12465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3U99_RS12480	COG3424	synthase
G3U99_RS12615	COG0840	transmembrane signaling receptor activity
G3U99_RS12800	COG0789	Transcriptional regulator
G3U99_RS12855	COG1067	ATP-dependent peptidase activity
G3U99_RS12860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G3U99_RS12875	COG0488	(ABC) transporter
G3U99_RS12885	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G3U99_RS12885	COG0116	Belongs to the methyltransferase superfamily
G3U99_RS12895	COG0167	dihydroorotate dehydrogenase activity
G3U99_RS12910	COG0308	aminopeptidase N
G3U99_RS12925	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
G3U99_RS12930	COG1956	GAF domain-containing protein
G3U99_RS12935	COG1132	(ABC) transporter
G3U99_RS12940	COG2995	paraquat-inducible protein a
G3U99_RS12945	COG3008	intermembrane lipid transfer
G3U99_RS12975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3U99_RS12990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3U99_RS12995	COG4597	amino acid ABC transporter
G3U99_RS13000	COG0765	amino acid transport
G3U99_RS13005	COG1126	abc transporter atp-binding protein
G3U99_RS13010	COG0670	Belongs to the BI1 family
G3U99_RS13015	COG2920	part of a sulfur-relay system
G3U99_RS13020	COG1254	Belongs to the acylphosphatase family
G3U99_RS13025	COG0840	transmembrane signaling receptor activity
G3U99_RS13030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G3U99_RS13060	COG0602	queuosine metabolic process
G3U99_RS13065	COG0561	phosphatase activity
G3U99_RS13085	COG2828	Protein conserved in bacteria
G3U99_RS13095	COG0372	Belongs to the citrate synthase family
G3U99_RS13100	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G3U99_RS13115	COG3501	Rhs element vgr protein
G3U99_RS13215	COG0515	serine threonine protein kinase
G3U99_RS13220	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G3U99_RS13245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_RS13260	COG4943	cyclic-guanylate-specific phosphodiesterase activity
G3U99_RS13280	COG0508	dehydrogenase complex catalyzes the overall conversion of
G3U99_RS13280	COG0596	Alpha beta hydrolase
G3U99_RS13285	COG3063	Type IV pilus biogenesis stability protein PilW
G3U99_RS13300	COG1451	nucleotide metabolic process
G3U99_RS13310	COG5002	protein histidine kinase activity
G3U99_RS13310	COG0784	Response regulator, receiver
G3U99_RS13320	COG1119	ATPase activity
G3U99_RS13330	COG2814	Major facilitator Superfamily
G3U99_RS13340	COG2203	Gaf domain
G3U99_RS13340	COG2199	diguanylate cyclase activity
G3U99_RS13360	COG4139	cobalamin transport
G3U99_RS13375	COG0406	alpha-ribazole phosphatase activity
G3U99_RS13385	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G3U99_RS13395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G3U99_RS13400	COG0702	epimerase
G3U99_RS13410	COG2925	Exonuclease
G3U99_RS13415	COG1380	Effector of murein hydrolase LrgA
G3U99_RS13420	COG1346	cytolysis
G3U99_RS13435	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G3U99_RS13510	COG0500	methyltransferase
G3U99_RS13530	COG4326	sporulation control protein
G3U99_RS13535	COG2188	Transcriptional regulator
G3U99_RS13540	COG1228	amidohydrolase
G3U99_RS13545	COG0010	Belongs to the arginase family
G3U99_RS13555	COG2986	histidine ammonia-lyase
G3U99_RS13570	COG0277	FAD linked oxidase domain protein
G3U99_RS13570	COG0247	lactate metabolic process
G3U99_RS13585	COG2885	chlorophyll binding
G3U99_RS13600	COG0625	glutathione transferase activity
G3U99_RS13610	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G3U99_RS13620	COG2195	Cleaves the N-terminal amino acid of tripeptides
G3U99_RS13635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3U99_RS13640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G3U99_RS13650	COG0456	acetyltransferase
G3U99_RS13675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3U99_RS13680	COG0454	-acetyltransferase
G3U99_RS13735	COG3122	Protein conserved in bacteria
G3U99_RS13750	COG3040	lipid binding
G3U99_RS13770	COG0456	acetyltransferase
G3U99_RS13785	COG2824	Alkylphosphonate utilization operon protein PhnA
G3U99_RS13795	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_RS13805	COG0730	response to heat
G3U99_RS13830	COG4628	conserved protein (DUF2132)
G3U99_RS13885	COG3755	Protein conserved in bacteria
G3U99_RS14065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3U99_RS14065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G3U99_RS14070	COG0346	lactoylglutathione lyase activity
G3U99_RS14085	COG0346	lactoylglutathione lyase activity
G3U99_RS14090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G3U99_RS14200	COG2962	Rard protein
G3U99_RS14205	COG0531	amino acid
G3U99_RS14215	COG0783	Belongs to the Dps family
G3U99_RS14220	COG4667	esterase of the alpha-beta hydrolase superfamily
G3U99_RS14255	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3U99_RS14270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G3U99_RS14275	COG3108	Peptidase M15
G3U99_RS14280	COG2989	Protein conserved in bacteria
G3U99_RS14305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G3U99_RS14315	COG3706	GGDEF domain
G3U99_RS14335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3U99_RS14345	COG3768	UPF0283 membrane protein
G3U99_RS14350	COG3106	COG3106 Predicted ATPase
G3U99_RS14370	COG2205	protein histidine kinase activity
G3U99_RS14370	COG0784	Response regulator, receiver
G3U99_RS14380	COG0494	nUDIX hydrolase
G3U99_RS14385	COG0814	amino acid
G3U99_RS14390	COG1760	l-serine dehydratase
G3U99_RS14400	COG0814	amino acid
G3U99_RS14415	COG0017	Asparaginyl-tRNA synthetase
G3U99_RS14430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3U99_RS14440	COG2770	Histidine kinase
G3U99_RS14440	COG3437	response regulator, receiver
G3U99_RS14445	COG1448	Aminotransferase
G3U99_RS14460	COG1643	Atp-dependent helicase
G3U99_RS14465	COG0281	malic enzyme
G3U99_RS14475	COG2949	membrane
G3U99_RS14485	COG0612	Peptidase, M16
G3U99_RS14515	COG0492	ferredoxin-NADP+ reductase activity
G3U99_RS14520	COG4988	ABC transporter
G3U99_RS14525	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G3U99_RS14530	COG2814	Major facilitator Superfamily
G3U99_RS14540	COG0384	phenazine biosynthesis protein PhzF
G3U99_RS14545	COG1187	pseudouridine synthase activity
G3U99_RS14560	COG0009	L-threonylcarbamoyladenylate synthase
G3U99_RS14565	COG0613	PHP domain protein
G3U99_RS14575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G3U99_RS14580	COG0512	Glutamine amidotransferase of anthranilate synthase
G3U99_RS14585	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G3U99_RS14590	COG0135	phosphoribosylanthranilate isomerase activity
G3U99_RS14590	COG0134	indole-3-glycerol-phosphate synthase activity
G3U99_RS14600	COG0159	tryptophan synthase activity
G3U99_RS14605	COG1301	dicarboxylic acid transport
G3U99_RS14615	COG1643	Atp-dependent helicase
G3U99_RS14670	COG0443	Heat shock 70 kDa protein
G3U99_RS14675	COG0443	Heat shock 70 kDa protein
G3U99_RS14685	COG1858	cytochrome C peroxidase
G3U99_RS14730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G3U99_RS14735	COG0840	transmembrane signaling receptor activity
G3U99_RS14755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G3U99_RS14760	COG0673	inositol 2-dehydrogenase activity
G3U99_RS14770	COG0583	DNA-binding transcription factor activity
G3U99_RS14780	COG1846	Transcriptional regulator
G3U99_RS14785	COG1764	response to oxidative stress
G3U99_RS14790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G3U99_RS14820	COG1032	radical SAM domain protein
G3U99_RS14830	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G3U99_RS14840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3U99_RS14840	COG4191	Histidine kinase
G3U99_RS14855	COG3070	regulator of competence-specific genes
G3U99_RS14865	COG2431	L-lysine efflux transmembrane transporter activity
G3U99_RS14875	COG0076	glutamate decarboxylase activity
G3U99_RS14880	COG1737	Transcriptional regulator
G3U99_RS14885	COG1454	alcohol dehydrogenase
G3U99_RS14885	COG1012	belongs to the aldehyde dehydrogenase family
G3U99_RS14890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G3U99_RS14925	COG1882	Formate acetyltransferase
G3U99_RS14940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G3U99_RS14955	COG3713	MltA-interacting MipA family protein
G3U99_RS14960	COG2766	serine protein kinase
G3U99_RS14965	COG2718	Belongs to the UPF0229 family
G3U99_RS14970	COG2719	SpoVR family
G3U99_RS14975	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G3U99_RS14980	COG2835	tetraacyldisaccharide 4'-kinase activity
G3U99_RS14990	COG1132	(ABC) transporter
G3U99_RS14995	COG0658	competence protein
G3U99_RS14995	COG2333	competence protein COMEC
G3U99_RS15005	COG4591	ABC-type transport system involved in lipoprotein release permease component
G3U99_RS15010	COG1136	(ABC) transporter
G3U99_RS15015	COG4591	ABC-type transport system involved in lipoprotein release permease component
G3U99_RS15025	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G3U99_RS15045	COG1252	NADH dehydrogenase
G3U99_RS15075	COG0537	adenosine 5'-monophosphoramidase activity
G3U99_RS15090	COG2186	Transcriptional regulator
G3U99_RS15095	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G3U99_RS15105	COG1674	ftsk spoiiie
G3U99_RS15115	COG0686	Belongs to the AlaDH PNT family
G3U99_RS15120	COG3092	negative regulation of chromosome organization
G3U99_RS15125	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G3U99_RS15130	COG0280	phosphate acetyltransferase
G3U99_RS15130	COG0857	belongs to the CobB CobQ family
G3U99_RS15135	COG3706	GGDEF domain
G3U99_RS15140	COG0435	Glutathione S-transferase
G3U99_RS15150	COG0444	Belongs to the ABC transporter superfamily
G3U99_RS15155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3U99_RS15160	COG0601	transmembrane transport
G3U99_RS15175	COG2067	long-chain fatty acid transport protein
G3U99_RS15180	COG3706	GGDEF domain
G3U99_RS15205	COG1404	Belongs to the peptidase S8 family
G3U99_RS15210	COG0840	transmembrane signaling receptor activity
G3U99_RS15225	COG0330	HflC and HflK could
G3U99_RS15245	COG0577	efflux transmembrane transporter activity
G3U99_RS15245	COG1136	(ABC) transporter
G3U99_RS15250	COG0577	efflux transmembrane transporter activity
G3U99_RS15250	COG1136	(ABC) transporter
G3U99_RS15255	COG0577	efflux transmembrane transporter activity
G3U99_RS15265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_RS15275	COG3227	Zinc metalloprotease (Elastase)
G3U99_RS15285	COG1770	oligopeptidase
G3U99_RS15290	COG3397	chitin binding
G3U99_RS15310	COG3876	Protein conserved in bacteria
G3U99_RS15315	COG1472	Belongs to the glycosyl hydrolase 3 family
G3U99_RS15335	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G3U99_RS15340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3U99_RS15345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3U99_RS15360	COG2855	membrane
G3U99_RS15380	COG0730	response to heat
G3U99_RS15385	COG0280	phosphate acetyltransferase
G3U99_RS15390	COG1414	Transcriptional regulator
G3U99_RS15425	COG3706	GGDEF domain
G3U99_RS15440	COG3126	Type III secretion system lipoprotein chaperone (YscW)
G3U99_RS15445	COG1946	Acyl-CoA thioesterase
G3U99_RS15460	COG1522	sequence-specific DNA binding
G3U99_RS15485	COG0477	Major facilitator Superfamily
G3U99_RS15490	COG2855	membrane
G3U99_RS15500	COG0318	PFAM AMP-dependent synthetase and ligase
G3U99_RS15515	COG0596	Alpha beta hydrolase
G3U99_RS15520	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G3U99_RS15525	COG1169	isochorismate synthase
G3U99_RS15530	COG0436	Aminotransferase
G3U99_RS15535	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
G3U99_RS15545	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G3U99_RS15550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G3U99_RS15565	COG0513	Belongs to the DEAD box helicase family
G3U99_RS15570	COG0616	signal peptide processing
G3U99_RS15575	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_RS15590	COG0587	DNA-directed DNA polymerase activity
G3U99_RS15595	COG0784	Response regulator, receiver
G3U99_RS15595	COG0835	chemotaxis
G3U99_RS15600	COG1940	carbohydrate kinase activity
G3U99_RS15605	COG0469	pyruvate kinase activity
G3U99_RS15610	COG4667	esterase of the alpha-beta hydrolase superfamily
G3U99_RS15625	COG0733	neurotransmitter:sodium symporter activity
G3U99_RS15640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G3U99_RS15640	COG1263	PTS System
G3U99_RS15645	COG0084	hydrolase, TatD family'
G3U99_RS15650	COG0470	DNA polymerase III
G3U99_RS15655	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G3U99_RS15660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G3U99_RS15665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G3U99_RS15690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3U99_RS15705	COG1399	metal-binding, possibly nucleic acid-binding protein
G3U99_RS15710	COG0424	maF-like protein
G3U99_RS15715	COG0564	pseudouridine synthase activity
G3U99_RS15720	COG1530	ribonuclease E activity
G3U99_RS15725	COG0659	secondary active sulfate transmembrane transporter activity
G3U99_RS15730	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
G3U99_RS15735	COG0318	PFAM AMP-dependent synthetase and ligase
G3U99_RS15755	COG1214	PFAM Peptidase M22, glycoprotease
G3U99_RS15760	COG1199	ATP-dependent helicase activity
G3U99_RS15770	COG0788	formyltetrahydrofolate deformylase activity
G3U99_RS15775	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3U99_RS15775	COG1902	pentaerythritol trinitrate reductase activity
G3U99_RS15780	COG0616	signal peptide processing
G3U99_RS15785	COG0252	asparaginase activity
G3U99_RS15795	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G3U99_RS15800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G3U99_RS15815	COG2165	general secretion pathway protein
G3U99_RS15820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G3U99_RS15825	COG3706	GGDEF domain
G3U99_RS15835	COG4120	Belongs to the binding-protein-dependent transport system permease family
G3U99_RS15870	COG0284	orotidine-5'-phosphate decarboxylase activity
G3U99_RS15875	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G3U99_RS15880	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
G3U99_RS15890	COG0539	negative regulation of cytoplasmic translation
G3U99_RS15900	COG1555	photosystem II stabilization
G3U99_RS15905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3U99_RS15910	COG0776	regulation of translation
G3U99_RS15915	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G3U99_RS15940	COG2204	response regulator
G3U99_RS15950	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3U99_RS15955	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G3U99_RS15960	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3U99_RS15965	COG3842	ATPase activity
G3U99_RS15975	COG1175	transmembrane transport
G3U99_RS15980	COG1653	transport
G3U99_RS15990	COG0745	RESPONSE REGULATOR receiver
G3U99_RS16015	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G3U99_RS16030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G3U99_RS16035	COG2832	Protein of unknown function (DUF454)
G3U99_RS16040	COG0745	RESPONSE REGULATOR receiver
G3U99_RS16045	COG0583	DNA-binding transcription factor activity
G3U99_RS16050	COG0778	Nitroreductase
G3U99_RS16060	COG0183	Belongs to the thiolase family
G3U99_RS16075	COG2067	long-chain fatty acid transport protein
G3U99_RS16080	COG2067	long-chain fatty acid transport protein
G3U99_RS16085	COG2853	Lipoprotein
G3U99_RS16095	COG4235	cytochrome complex assembly
G3U99_RS16095	COG3088	subunit of a heme lyase
G3U99_RS16100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G3U99_RS16105	COG1138	Cytochrome C-type biogenesis protein
G3U99_RS16115	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G3U99_RS16120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G3U99_RS16125	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G3U99_RS16130	COG4133	protoheme IX ABC transporter activity
G3U99_RS16140	COG0835	chemotaxis
G3U99_RS16150	COG1192	Involved in chromosome partitioning
G3U99_RS16155	COG2201	protein-glutamate methylesterase activity
G3U99_RS16160	COG0643	Histidine kinase
G3U99_RS16160	COG0784	Response regulator, receiver
G3U99_RS16160	COG2198	Histidine kinase
G3U99_RS16165	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
G3U99_RS16195	COG2062	phosphohistidine phosphatase, SixA
G3U99_RS16200	COG1025	Belongs to the peptidase M16 family
G3U99_RS16205	COG3102	Protein conserved in bacteria
G3U99_RS16210	COG0018	arginyl-trna synthetase
G3U99_RS16225	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
G3U99_RS16230	COG1918	ferrous iron import across plasma membrane
G3U99_RS16235	COG4977	sequence-specific DNA binding
G3U99_RS16240	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
G3U99_RS16245	COG1121	(ABC) transporter
G3U99_RS16250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G3U99_RS16255	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G3U99_RS16260	COG1286	toxin biosynthetic process
G3U99_RS16265	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
G3U99_RS16270	COG0285	dihydrofolate synthase activity
G3U99_RS16275	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G3U99_RS16280	COG0101	tRNA pseudouridine synthase activity
G3U99_RS16290	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G3U99_RS16295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G3U99_RS16300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3U99_RS16335	COG2205	protein histidine kinase activity
G3U99_RS16340	COG0745	RESPONSE REGULATOR receiver
G3U99_RS16360	COG0628	permease
G3U99_RS16400	COG2860	membrane
G3U99_RS16410	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G3U99_RS16415	COG2890	protein-(glutamine-N5) methyltransferase activity
G3U99_RS16430	COG1684	flagellar biosynthetic protein fliR
G3U99_RS16435	COG1987	bacterial-type flagellum assembly
G3U99_RS16490	COG2146	nitrite reductase [NAD(P)H] activity
G3U99_RS16495	COG2146	nitrite reductase [NAD(P)H] activity
G3U99_RS16495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G3U99_RS16500	COG1116	anion transmembrane transporter activity
G3U99_RS16505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3U99_RS16510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3U99_RS16510	COG1116	anion transmembrane transporter activity
G3U99_RS16520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G3U99_RS16525	COG1648	precorrin-2 dehydrogenase activity
G3U99_RS16525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G3U99_RS16530	COG0243	molybdopterin cofactor binding
G3U99_RS16570	COG2315	Protein conserved in bacteria
G3U99_RS16580	COG2203	Gaf domain
G3U99_RS16580	COG2199	diguanylate cyclase activity
G3U99_RS16605	COG3706	GGDEF domain
G3U99_RS16625	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
G3U99_RS16630	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_RS16640	COG1024	Enoyl-CoA hydratase
G3U99_RS16645	COG1024	Enoyl-CoA hydratase
G3U99_RS16660	COG0183	Belongs to the thiolase family
G3U99_RS16670	COG1960	acyl-CoA dehydrogenase activity
G3U99_RS16675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G3U99_RS16710	COG2259	Doxx family
G3U99_RS16715	COG1741	Belongs to the pirin family
G3U99_RS16730	COG1115	amino acid carrier protein
G3U99_RS16735	COG0583	DNA-binding transcription factor activity
G3U99_RS16740	COG2910	NAD(P)H-binding
G3U99_RS16760	COG1716	ATPase activity
G3U99_RS16760	COG5001	Diguanylate cyclase
G3U99_RS16785	COG1858	cytochrome C peroxidase
G3U99_RS16815	COG0583	DNA-binding transcription factor activity
G3U99_RS16820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G3U99_RS16825	COG3300	MHYT domain
G3U99_RS16825	COG5001	Diguanylate cyclase
G3U99_RS16835	COG0789	Transcriptional regulator
G3U99_RS16845	COG2176	DNA-directed DNA polymerase activity
G3U99_RS16850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3U99_RS16855	COG1846	Transcriptional regulator
G3U99_RS16860	COG3706	GGDEF domain
G3U99_RS16885	COG2814	Major facilitator Superfamily
G3U99_RS16890	COG2425	protein containing a von Willebrand factor type A (vWA) domain
G3U99_RS16895	COG0714	Associated with various cellular activities
G3U99_RS16900	COG0494	nUDIX hydrolase
G3U99_RS16910	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_RS16920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G3U99_RS16925	COG0784	Response regulator, receiver
G3U99_RS16925	COG0835	chemotaxis
G3U99_RS16930	COG3706	GGDEF domain
G3U99_RS16955	COG1760	l-serine dehydratase
G3U99_RS16960	COG0583	DNA-binding transcription factor activity
G3U99_RS16970	COG2866	Carboxypeptidase
G3U99_RS16975	COG3104	oligopeptide transport
G3U99_RS17000	COG3842	ATPase activity
G3U99_RS17010	COG1840	ABC-type Fe3 transport system, periplasmic component
G3U99_RS17015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G3U99_RS17050	COG1011	Hydrolase
G3U99_RS17065	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
G3U99_RS17070	COG1454	alcohol dehydrogenase
G3U99_RS17115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3U99_RS17120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G3U99_RS17160	COG3186	Phenylalanine-4-hydroxylase
G3U99_RS17165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G3U99_RS17170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G3U99_RS17190	COG2205	protein histidine kinase activity
G3U99_RS17190	COG0784	Response regulator, receiver
G3U99_RS17195	COG2205	protein histidine kinase activity
G3U99_RS17195	COG0784	Response regulator, receiver
G3U99_RS17200	COG0612	Peptidase, M16
G3U99_RS17210	COG0798	PFAM Bile acid sodium symporter
G3U99_RS17240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G3U99_RS17270	COG1063	alcohol dehydrogenase
G3U99_RS17275	COG0156	8-amino-7-oxononanoate synthase activity
G3U99_RS17280	COG2202	Pas domain
G3U99_RS17280	COG2199	diguanylate cyclase activity
G3U99_RS17280	COG2200	EAL domain
G3U99_RS17300	COG0346	lactoylglutathione lyase activity
G3U99_RS17310	COG4452	Inner membrane protein CreD
G3U99_RS17315	COG2205	protein histidine kinase activity
G3U99_RS17320	COG0745	RESPONSE REGULATOR receiver
G3U99_RS17330	COG0745	RESPONSE REGULATOR receiver
G3U99_RS17335	COG2205	protein histidine kinase activity
G3U99_RS17350	COG0667	Aldo Keto reductase
G3U99_RS17355	COG0583	DNA-binding transcription factor activity
G3U99_RS17370	COG0714	Associated with various cellular activities
G3U99_RS17385	COG2304	oxidoreductase activity
G3U99_RS17390	COG2304	oxidoreductase activity
G3U99_RS17410	COG0110	maltose O-acetyltransferase activity
G3U99_RS17415	COG1765	OsmC-like protein
G3U99_RS17420	COG0673	inositol 2-dehydrogenase activity
G3U99_RS17440	COG0531	amino acid
G3U99_RS17460	COG2205	protein histidine kinase activity
G3U99_RS17465	COG0745	RESPONSE REGULATOR receiver
G3U99_RS17490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_RS17495	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G3U99_RS17500	COG0402	S-adenosylhomocysteine deaminase activity
G3U99_RS17505	COG0861	Integral membrane protein TerC family
G3U99_RS17515	COG5002	protein histidine kinase activity
G3U99_RS17515	COG2205	protein histidine kinase activity
G3U99_RS17515	COG0784	Response regulator, receiver
G3U99_RS17555	COG3833	ABC-type maltose transport systems, permease component
G3U99_RS17560	COG1175	transmembrane transport
G3U99_RS17570	COG3842	ATPase activity
G3U99_RS17575	COG2096	Adenosyltransferase
G3U99_RS17580	COG0748	coenzyme F420 binding
G3U99_RS17585	COG3721	Heme iron utilization protein
G3U99_RS17595	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
G3U99_RS17600	COG0811	peptide transport
G3U99_RS17605	COG0848	biopolymer transport protein
G3U99_RS17615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3U99_RS17620	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G3U99_RS17625	COG2814	Major facilitator Superfamily
G3U99_RS17635	COG0739	heme binding
G3U99_RS17650	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G3U99_RS17660	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
G3U99_RS17670	COG0513	Belongs to the DEAD box helicase family
G3U99_RS17680	COG4191	Histidine kinase
G3U99_RS17680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3U99_RS17685	COG3437	response regulator, receiver
G3U99_RS17685	COG0784	Response regulator, receiver
G3U99_RS17690	COG1609	Transcriptional regulator
G3U99_RS17695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_RS17700	COG1879	ABC-type sugar transport system periplasmic component
G3U99_RS17705	COG1172	Belongs to the binding-protein-dependent transport system permease family
G3U99_RS17710	COG1129	ABC transporter
G3U99_RS17715	COG1869	D-ribose catabolic process
G3U99_RS17725	COG3469	chitinase activity
G3U99_RS17740	COG0004	ammonium transporteR
G3U99_RS17765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3U99_RS17785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3U99_RS17790	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
G3U99_RS17820	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
G3U99_RS17825	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G3U99_RS17830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3U99_RS17835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3U99_RS17855	COG1609	Transcriptional regulator
G3U99_RS17860	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G3U99_RS17865	COG3265	gluconokinase activity
G3U99_RS17870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3U99_RS17880	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G3U99_RS17905	COG0583	DNA-binding transcription factor activity
G3U99_RS17925	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G3U99_RS17935	COG0668	transmembrane transport
G3U99_RS17955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G3U99_RS17995	COG3118	belongs to the thioredoxin family
G3U99_RS18000	COG4232	protein-disulfide reductase activity
G3U99_RS18015	COG1280	lysine exporter protein (LysE YggA)
G3U99_RS18045	COG0443	Heat shock 70 kDa protein
G3U99_RS18050	COG0583	DNA-binding transcription factor activity
G3U99_RS18060	COG4948	Mandelate Racemase Muconate Lactonizing
G3U99_RS18065	COG1396	sequence-specific DNA binding
G3U99_RS18070	COG5001	Diguanylate cyclase
G3U99_RS18080	COG3706	GGDEF domain
G3U99_RS18090	COG0642	Histidine kinase
G3U99_RS18095	COG0745	RESPONSE REGULATOR receiver
G3U99_RS18110	COG2130	NADP-dependent
G3U99_RS18165	COG0366	Alpha amylase catalytic
G3U99_RS18195	COG3279	Response regulator of the LytR AlgR family
G3U99_RS18200	COG3275	phosphorelay sensor kinase activity
G3U99_RS18215	COG4591	ABC-type transport system involved in lipoprotein release permease component
G3U99_RS18220	COG1136	(ABC) transporter
G3U99_RS18255	COG3530	Putative quorum-sensing-regulated virulence factor
G3U99_RS18270	COG1686	Belongs to the peptidase S11 family
G3U99_RS18285	COG3036	rescue of stalled ribosome
G3U99_RS18290	COG1278	Cold shock
G3U99_RS18305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3U99_RS18305	COG1017	nitric oxide dioxygenase activity
G3U99_RS18310	COG3604	Transcriptional regulator
G3U99_RS18320	COG0546	phosphoglycolate phosphatase activity
G3U99_RS18325	COG2249	NAD(P)H dehydrogenase (quinone) activity
G3U99_RS18335	COG0534	Mate efflux family protein
G3U99_RS18345	COG0697	spore germination
G3U99_RS18360	COG2814	Major facilitator Superfamily
G3U99_RS18365	COG0583	DNA-binding transcription factor activity
G3U99_RS18370	COG5001	Diguanylate cyclase
G3U99_RS18445	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
G3U99_RS18480	COG0438	transferase activity, transferring glycosyl groups
G3U99_RS18485	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G3U99_RS18490	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G3U99_RS18495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G3U99_RS18500	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G3U99_RS18510	COG5001	Diguanylate cyclase
G3U99_RS18510	COG4251	negative regulation of phosphorylation
G3U99_RS18510	COG3706	GGDEF domain
G3U99_RS18510	COG2203	Gaf domain
G3U99_RS18515	COG4989	oxidoreductase activity
G3U99_RS18525	COG0366	Alpha amylase catalytic
G3U99_RS18535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G3U99_RS18540	COG1126	abc transporter atp-binding protein
G3U99_RS18545	COG0765	amino acid transport
G3U99_RS18550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3U99_RS18555	COG0765	amino acid transport
G3U99_RS18560	COG0109	protoheme IX farnesyltransferase activity
G3U99_RS18565	COG1612	heme a metabolic process
G3U99_RS18590	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
G3U99_RS18595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3U99_RS18600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3U99_RS18605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3U99_RS18645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3U99_RS18685	COG1741	Belongs to the pirin family
G3U99_RS18695	COG2814	Major facilitator Superfamily
G3U99_RS18700	COG1686	Belongs to the peptidase S11 family
G3U99_RS18705	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G3U99_RS18710	COG0583	DNA-binding transcription factor activity
G3U99_RS18745	COG1253	flavin adenine dinucleotide binding
G3U99_RS18785	COG1280	lysine exporter protein (LysE YggA)
G3U99_RS18790	COG0583	DNA-binding transcription factor activity
G3U99_RS18845	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G3U99_RS18855	COG0523	cobalamin synthesis protein
G3U99_RS18860	COG2988	succinylglutamate desuccinylase activity
G3U99_RS18865	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
G3U99_RS18905	COG1846	Transcriptional regulator
G3U99_RS18915	COG1280	lysine exporter protein (LysE YggA)
G3U99_RS18930	COG1176	ABC-type spermidine putrescine transport system, permease component I
G3U99_RS18935	COG3842	ATPase activity
G3U99_RS18940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G3U99_RS18945	COG2423	ornithine cyclodeaminase activity
G3U99_RS18960	COG3938	Belongs to the proline racemase family
G3U99_RS18970	COG2186	Transcriptional regulator
G3U99_RS18985	COG0601	transmembrane transport
G3U99_RS18990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3U99_RS19005	COG0006	proline dipeptidase activity
G3U99_RS19050	COG3568	Endonuclease Exonuclease Phosphatase
G3U99_RS19060	COG3291	Pkd domain containing protein
G3U99_RS19065	COG0513	Belongs to the DEAD box helicase family
G3U99_RS19100	COG1376	ErfK ybiS ycfS ynhG family protein
G3U99_RS19100	COG1388	LysM domain
G3U99_RS19105	COG0415	Belongs to the DNA photolyase family
G3U99_RS19110	COG0789	Transcriptional regulator
G3U99_RS19115	COG3272	Protein of unknown function (DUF1722)
G3U99_RS19120	COG0813	purine-nucleoside phosphorylase activity
G3U99_RS19135	COG3706	GGDEF domain
G3U99_RS19150	COG1566	PFAM secretion protein HlyD family protein
G3U99_RS19155	COG0786	glutamate:sodium symporter activity
G3U99_RS19165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G3U99_RS19180	COG0583	DNA-binding transcription factor activity
G3U99_RS19190	COG1132	(ABC) transporter
G3U99_RS19235	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G3U99_RS19245	COG0259	pyridoxamine-phosphate oxidase activity
G3U99_RS19275	COG3033	Beta-eliminating lyase
G3U99_RS19280	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
G3U99_RS19285	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G3U99_RS19290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3U99_RS19300	COG1999	signal sequence binding
G3U99_RS19315	COG1671	Belongs to the UPF0178 family
G3U99_RS19320	COG0393	Putative heavy-metal-binding
G3U99_RS19325	COG0583	DNA-binding transcription factor activity
G3U99_RS19330	COG2814	Major facilitator Superfamily
G3U99_RS19350	COG0584	glycerophosphoryl diester phosphodiesterase
G3U99_RS19355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3U99_RS19365	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3U99_RS19380	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_RS19385	COG0583	DNA-binding transcription factor activity
G3U99_RS19405	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G3U99_RS19560	COG1301	dicarboxylic acid transport
G3U99_RS19580	COG1404	Belongs to the peptidase S8 family
G3U99_RS19590	COG2207	Transcriptional regulator
G3U99_RS19600	COG0700	Nucleoside recognition
G3U99_RS19605	COG3366	ferrous iron transmembrane transporter activity
G3U99_RS19610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G3U99_RS19625	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
G3U99_RS19635	COG0745	RESPONSE REGULATOR receiver
G3U99_RS19640	COG5002	protein histidine kinase activity
G3U99_RS19655	COG3850	Histidine kinase
G3U99_RS19655	COG2205	protein histidine kinase activity
G3U99_RS19655	COG4999	Histidine kinase
G3U99_RS19655	COG3437	response regulator, receiver
G3U99_RS19660	COG0745	RESPONSE REGULATOR receiver
G3U99_RS19665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_RS19670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3U99_RS19675	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G3U99_RS19700	COG0745	RESPONSE REGULATOR receiver
G3U99_RS19705	COG2205	protein histidine kinase activity
G3U99_RS19710	COG0471	metal ion transport
G3U99_RS19750	COG1595	DNA-templated transcription, initiation
G3U99_RS19770	COG0251	oxidation-reduction process
G3U99_RS19780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3U99_RS19780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G3U99_RS19795	COG0604	alcohol dehydrogenase
G3U99_RS19835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G3U99_RS19845	COG1175	transmembrane transport
G3U99_RS19870	COG0438	transferase activity, transferring glycosyl groups
G3U99_RS19880	COG0671	phosphoesterase, PA-phosphatase related
G3U99_RS19890	COG3708	Transcriptional regulator
G3U99_RS19890	COG2207	Transcriptional regulator
G3U99_RS19910	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G3U99_RS19915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G3U99_RS19920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G3U99_RS19925	COG1116	anion transmembrane transporter activity
G3U99_RS19930	COG0351	phosphomethylpyrimidine kinase
G3U99_RS19935	COG0656	L-ascorbic acid biosynthetic process
G3U99_RS19940	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_RS19940	COG3321	synthase
G3U99_RS19940	COG0604	alcohol dehydrogenase
G3U99_RS19955	COG0583	DNA-binding transcription factor activity
G3U99_RS19980	COG0840	transmembrane signaling receptor activity
G3U99_RS19985	COG0768	penicillin binding
G3U99_RS19990	COG2723	6-phospho-beta-galactosidase activity
G3U99_RS20000	COG0589	response to stress
G3U99_RS20005	COG3842	ATPase activity
G3U99_RS20010	COG0546	phosphoglycolate phosphatase activity
G3U99_RS20030	COG1175	transmembrane transport
G3U99_RS20035	COG0583	DNA-binding transcription factor activity
G3U99_RS20070	COG0604	alcohol dehydrogenase
G3U99_RS20070	COG3321	synthase
G3U99_RS20070	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_RS20080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G3U99_RS20105	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G3U99_RS20150	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G3U99_RS20155	COG0840	transmembrane signaling receptor activity
G3U99_RS20160	COG0835	chemotaxis
G3U99_RS20185	COG0840	transmembrane signaling receptor activity
G3U99_RS20190	COG1444	tRNA N-acetyltransferase activity
G3U99_RS20220	COG4608	Belongs to the ABC transporter superfamily
G3U99_RS20225	COG0444	Belongs to the ABC transporter superfamily
G3U99_RS20260	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_RS20270	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_RS20275	COG1733	regulation of RNA biosynthetic process
G3U99_RS20295	COG0583	DNA-binding transcription factor activity
G3U99_RS20300	COG1051	belongs to the nudix hydrolase family
G3U99_RS20315	COG5001	Diguanylate cyclase
G3U99_RS20315	COG3300	MHYT domain
G3U99_RS20320	COG0697	spore germination
G3U99_RS20325	COG1846	Transcriptional regulator
G3U99_RS20355	COG1288	antiporter activity
G3U99_RS20360	COG0583	DNA-binding transcription factor activity
G3U99_RS20370	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G3U99_RS20375	COG3960	tartronate-semialdehyde synthase activity
G3U99_RS20380	COG3622	Belongs to the hyi family
G3U99_RS20385	COG2084	Dehydrogenase
G3U99_RS20400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G3U99_RS20420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G3U99_RS20430	COG1733	regulation of RNA biosynthetic process
G3U99_RS20440	COG4974	Belongs to the 'phage' integrase family
G3U99_RS20450	COG0559	Belongs to the binding-protein-dependent transport system permease family
G3U99_RS20475	COG0831	urea catabolic process
G3U99_RS20480	COG0832	Belongs to the urease beta subunit family
G3U99_RS20485	COG0804	urea catabolic process
G3U99_RS20490	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
G3U99_RS20535	COG0840	transmembrane signaling receptor activity
G3U99_RS20555	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G3U99_RS20565	COG4145	pantothenate transmembrane transporter activity
G3U99_RS20570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_RS20575	COG0800	Aldolase
G3U99_RS20585	COG2706	6-phosphogluconolactonase activity
G3U99_RS20590	COG0251	oxidation-reduction process
G3U99_RS20595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G3U99_RS20600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G3U99_RS20605	COG1845	cytochrome c oxidase, subunit III
G3U99_RS20610	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G3U99_RS20615	COG0109	protoheme IX farnesyltransferase activity
G3U99_RS20665	COG0583	DNA-binding transcription factor activity
G3U99_RS20680	COG2205	protein histidine kinase activity
G3U99_RS20695	COG3214	Protein conserved in bacteria
G3U99_RS20700	COG0596	Alpha beta hydrolase
G3U99_RS20715	COG2252	PERMEase
G3U99_RS20735	COG4266	Belongs to the allantoicase family
G3U99_RS20740	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
G3U99_RS20750	COG0840	transmembrane signaling receptor activity
G3U99_RS20760	COG1522	sequence-specific DNA binding
G3U99_RS20770	COG2205	protein histidine kinase activity
G3U99_RS20770	COG5002	protein histidine kinase activity
G3U99_RS20770	COG0784	Response regulator, receiver
G3U99_RS20775	COG2226	methyltransferase
G3U99_RS20780	COG0402	S-adenosylhomocysteine deaminase activity
G3U99_RS20790	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G3U99_RS20800	COG2186	Transcriptional regulator
G3U99_RS20825	COG3795	YCII-related domain
G3U99_RS20855	COG0402	S-adenosylhomocysteine deaminase activity
G3U99_RS20860	COG1404	Belongs to the peptidase S8 family
G3U99_RS20865	COG1335	isochorismatase
G3U99_RS20870	COG2207	Transcriptional regulator
G3U99_RS20905	COG0456	acetyltransferase
G3U99_RS20915	COG2909	trisaccharide binding
G3U99_RS20920	COG0058	SHG alpha-glucan phosphorylase activity
G3U99_RS20925	COG1640	4-alpha-glucanotransferase
G3U99_RS20930	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G3U99_RS20945	COG1619	proteins homologs of microcin C7 resistance protein MccF
G3U99_RS20985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3U99_RS21000	COG2249	NAD(P)H dehydrogenase (quinone) activity
G3U99_RS21010	COG0583	DNA-binding transcription factor activity
G3U99_RS21020	COG0300	oxidoreductase activity
G3U99_RS21075	COG0561	phosphatase activity
G3U99_RS21115	COG1132	(ABC) transporter
G3U99_RS21120	COG1132	(ABC) transporter
G3U99_RS21125	COG1021	2,3-dihydroxybenzoate-AMP ligase
G3U99_RS21130	COG1169	isochorismate synthase
G3U99_RS21150	COG2226	methyltransferase
G3U99_RS21150	COG3433	isochorismatase activity
G3U99_RS21150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3U99_RS21155	COG2814	Major facilitator Superfamily
G3U99_RS21160	COG4771	TonB-dependent receptor
G3U99_RS21165	COG4977	sequence-specific DNA binding
G3U99_RS21165	COG1917	Cupin 2, conserved barrel domain protein
G3U99_RS21185	COG1733	regulation of RNA biosynthetic process
G3U99_RS21245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_RS21250	COG0383	alpha-mannosidase activity
G3U99_RS21260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_RS21260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_RS21260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_RS21265	COG4969	Belongs to the N-Me-Phe pilin family
G3U99_RS21280	COG1120	ATPase activity
G3U99_RS21295	COG4264	IucA IucC family
G3U99_RS21320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G3U99_RS21330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3U99_RS21340	COG0662	Cupin 2, conserved barrel domain protein
G3U99_RS21345	COG1960	acyl-CoA dehydrogenase activity
G3U99_RS21350	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G3U99_RS21355	COG2076	Multidrug Resistance protein
G3U99_RS21360	COG2076	Multidrug Resistance protein
G3U99_RS21365	COG0590	tRNA wobble adenosine to inosine editing
G3U99_RS21430	COG3448	diguanylate cyclase activity
G3U99_RS21430	COG4175	Glycine betaine
G3U99_RS21435	COG4176	ABC-type proline glycine betaine transport system permease component
G3U99_RS21455	COG2095	MarC family integral membrane protein
G3U99_RS21465	COG0534	Mate efflux family protein
G3U99_RS21475	COG0583	DNA-binding transcription factor activity
G3U99_RS21500	COG4964	Belongs to the GSP D family
G3U99_RS21510	COG2894	cell division
G3U99_RS21565	COG1477	protein flavinylation
G3U99_RS21585	COG4221	oxidoreductase activity
G3U99_RS21590	COG0840	transmembrane signaling receptor activity
G3U99_RS21600	COG0573	inorganic phosphate transmembrane transporter activity
G3U99_RS21605	COG0581	inorganic phosphate transmembrane transporter activity
G3U99_RS21610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G3U99_RS21625	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
G3U99_RS21630	COG1162	GTPase activity
G3U99_RS21650	COG1122	ATPase activity
G3U99_RS21655	COG4720	Psort location CytoplasmicMembrane, score
G3U99_RS21675	COG0454	-acetyltransferase
G3U99_RS21680	COG0840	transmembrane signaling receptor activity
G3U99_RS21710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G3U99_RS21715	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G3U99_RS21720	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
G3U99_RS21760	COG3608	succinylglutamate desuccinylase aspartoacylase
G3U99_RS21765	COG1288	antiporter activity
G3U99_RS21785	COG0745	RESPONSE REGULATOR receiver
G3U99_RS21830	COG0583	DNA-binding transcription factor activity
G3U99_RS21835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G3U99_RS21840	COG1151	hydroxylamine reductase activity
G3U99_RS21850	COG3706	GGDEF domain
G3U99_RS21855	COG0583	DNA-binding transcription factor activity
G3U99_RS21870	COG3604	Transcriptional regulator
G3U99_RS21900	COG0415	Belongs to the DNA photolyase family
G3U99_RS21915	COG2329	Antibiotic biosynthesis monooxygenase
G3U99_RS21920	COG3304	Inner membrane component domain
G3U99_RS21945	COG1234	tRNA 3'-trailer cleavage
G3U99_RS21975	COG0004	ammonium transporteR
G3U99_RS21980	COG3437	response regulator, receiver
G3U99_RS21985	COG3383	formate dehydrogenase (NAD+) activity
G3U99_RS21990	COG0446	pyridine nucleotide-disulphide oxidoreductase
G3U99_RS21995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G3U99_RS22000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G3U99_RS22025	COG0739	heme binding
G3U99_RS22030	COG3047	cAMP biosynthetic process
G3U99_RS22055	COG0300	oxidoreductase activity
G3U99_RS22060	COG5553	Cysteine dioxygenase type I
G3U99_RS22075	COG0673	inositol 2-dehydrogenase activity
G3U99_RS22080	COG0488	(ABC) transporter
G3U99_RS22110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G3U99_RS22110	COG4191	Histidine kinase
G3U99_RS22115	COG1132	(ABC) transporter
G3U99_RS22135	COG0625	glutathione transferase activity
G3U99_RS22145	COG1690	Belongs to the RtcB family
G3U99_RS22150	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G3U99_RS22175	COG3541	Predicted nucleotidyltransferase
G3U99_RS22180	COG1690	Belongs to the RtcB family
G3U99_RS22200	COG4650	regulator
G3U99_RS22215	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G3U99_RS22225	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G3U99_RS22240	COG4580	involved in the transport of maltose and maltodextrins
G3U99_RS22250	COG0840	transmembrane signaling receptor activity
G3U99_RS22280	COG0840	transmembrane signaling receptor activity
G3U99_RS22310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G3U99_RS22320	COG0415	Belongs to the DNA photolyase family
G3U99_RS22340	COG0697	spore germination
G3U99_RS22370	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3U99_RS22370	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G3U99_RS22380	COG2207	Transcriptional regulator
G3U99_RS22380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G3U99_RS22385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3U99_RS22405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G3U99_RS22415	COG1522	sequence-specific DNA binding
G3U99_RS22440	COG1357	PFAM Pentapeptide repeats (8 copies)
G3U99_RS22450	COG1294	oxidase, subunit
G3U99_RS22455	COG1271	oxidase subunit
G3U99_RS22460	COG1805	sodium ion transport
G3U99_RS22485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G3U99_RS22510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G3U99_RS22520	COG1309	transcriptional regulator
G3U99_RS22540	COG0745	RESPONSE REGULATOR receiver
G3U99_RS22545	COG5002	protein histidine kinase activity
G3U99_RS22580	COG0842	Transport permease protein
G3U99_RS22635	COG0110	maltose O-acetyltransferase activity
G3U99_RS22640	COG0346	lactoylglutathione lyase activity
G3U99_RS22645	COG0625	glutathione transferase activity
G3U99_RS22650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3U99_RS22660	COG0366	Alpha amylase catalytic
G3U99_RS22680	COG2084	Dehydrogenase
G3U99_RS22695	COG2130	NADP-dependent
G3U99_RS22700	COG1309	transcriptional regulator
G3U99_RS22705	COG3706	GGDEF domain
G3U99_RS22725	COG0513	Belongs to the DEAD box helicase family
G3U99_RS22735	COG5002	protein histidine kinase activity
G3U99_RS22735	COG3447	MASE1 domain protein
G3U99_RS22735	COG5001	Diguanylate cyclase
G3U99_RS22740	COG1574	metal-dependent hydrolase with the TIM-barrel fold
G3U99_RS22765	COG2204	response regulator
G3U99_RS22780	COG0573	inorganic phosphate transmembrane transporter activity
G3U99_RS22790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G3U99_RS22805	COG1175	transmembrane transport
G3U99_RS22810	COG0395	ABC-type sugar transport system, permease component
G3U99_RS22815	COG1554	hydrolase, family 65, central catalytic
G3U99_RS22820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3U99_RS22825	COG3842	ATPase activity
G3U99_RS22835	COG1621	beta-fructofuranosidase activity
G3U99_RS22845	COG0110	maltose O-acetyltransferase activity
G3U99_RS22875	COG0251	oxidation-reduction process
G3U99_RS22890	COG2356	endonuclease I
G3U99_RS22905	COG0564	pseudouridine synthase activity
G3U99_RS22930	COG0583	DNA-binding transcription factor activity
G3U99_RS22935	COG2814	Major facilitator Superfamily
G3U99_RS22965	COG0840	transmembrane signaling receptor activity
G3U99_RS22970	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G3U99_RS22980	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G3U99_RS22990	COG0579	oxidoreductase
G3U99_RS23020	COG1012	belongs to the aldehyde dehydrogenase family
G3U99_RS23025	COG3284	Transcriptional regulator
G3U99_RS23050	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G3U99_RS23055	COG0363	glucosamine-6-phosphate deaminase activity
G3U99_RS23060	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G3U99_RS23065	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G3U99_RS23075	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G3U99_RS23085	COG2271	Major facilitator Superfamily
G3U99_RS23090	COG3851	Histidine kinase
G3U99_RS23095	COG2197	response regulator
G3U99_RS23120	COG3217	Mosc domain protein beta barrel domain protein
G3U99_RS23120	COG3217	Mosc domain protein beta barrel domain protein
G3U99_RS23120	COG0633	Ferredoxin
G3U99_RS23120	COG0633	Ferredoxin
G3U99_RS23130	COG1349	DNA-binding transcription factor activity
G3U99_RS23155	COG2354	Protein conserved in bacteria
G3U99_RS23165	COG0366	Alpha amylase catalytic
G3U99_RS23200	COG0840	transmembrane signaling receptor activity
G3U99_RS23205	COG1366	Belongs to the anti-sigma-factor antagonist family
G3U99_RS23215	COG2172	sigma factor antagonist activity
G3U99_RS23225	COG3850	Histidine kinase
G3U99_RS23225	COG2205	protein histidine kinase activity
G3U99_RS23225	COG3437	response regulator, receiver
G3U99_RS23225	COG4999	Histidine kinase
G3U99_RS23230	COG3437	response regulator, receiver
G3U99_RS23245	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G3U99_RS23245	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G3U99_RS23250	COG0516	GMP reductase activity
G3U99_RS23255	COG0582	viral genome integration into host DNA
G3U99_RS23270	COG0563	adenylate kinase activity
G3U99_RS23400	COG3772	lysozyme
G3U99_RS23415	COG4695	Portal protein
G3U99_RS23455	COG4386	tail sheath protein
G3U99_RS23495	COG3646	Phage regulatory protein
G3U99_RS23545	COG1309	transcriptional regulator
G3U99_RS23570	COG3448	diguanylate cyclase activity
G3U99_RS23570	COG4175	Glycine betaine
G3U99_RS23590	COG1304	FMN binding
G3U99_RS23595	COG1620	l-lactate permease
G3U99_RS23600	COG0583	DNA-binding transcription factor activity
G3U99_RS23605	COG4172	Belongs to the ABC transporter superfamily
G3U99_RS23615	COG1067	ATP-dependent peptidase activity
G3U99_RS23620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G3U99_RS23625	COG0840	transmembrane signaling receptor activity
G3U99_RS23640	COG4166	transmembrane transport
G3U99_RS23645	COG4174	ABC transporter (Permease)
G3U99_RS23650	COG4239	(ABC) transporter, permease
G3U99_RS23655	COG4172	Belongs to the ABC transporter superfamily
G3U99_RS23705	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G3U99_RS23710	COG4605	iron ion homeostasis
G3U99_RS23715	COG4604	ABC transporter, ATP-binding protein
G3U99_RS23720	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G3U99_RS23735	COG0004	ammonium transporteR
G3U99_RS23745	COG2271	Major facilitator Superfamily
G3U99_RS23755	COG0840	transmembrane signaling receptor activity
G3U99_RS23760	COG2203	Gaf domain
G3U99_RS23760	COG2199	diguanylate cyclase activity
G3U99_RS23770	COG0739	heme binding
G3U99_RS23810	COG3501	Rhs element vgr protein
G3U99_RS23835	COG0515	serine threonine protein kinase
G3U99_RS23835	COG2815	serine threonine protein kinase
G3U99_RS23870	COG1522	sequence-specific DNA binding
G3U99_RS23910	COG3250	beta-galactosidase activity
G3U99_RS23915	COG2211	Major facilitator Superfamily
G3U99_RS23920	COG1609	Transcriptional regulator
G3U99_RS23925	COG1309	transcriptional regulator
G3U99_RS23930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_RS23935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G3U99_RS23950	COG0183	Belongs to the thiolase family
G3U99_RS23965	COG1794	racemase activity, acting on amino acids and derivatives
G3U99_RS23970	COG2814	Major facilitator Superfamily
G3U99_RS23975	COG3240	lipase activity
G3U99_RS24025	COG1328	CTP reductase activity
G3U99_RS24030	COG0602	queuosine metabolic process
G3U99_RS24040	COG0189	ligase activity
G3U99_RS24040	COG4067	protein conserved in archaea
G3U99_RS24050	COG0545	Peptidyl-prolyl cis-trans isomerase
G3U99_RS24070	COG0247	lactate metabolic process
G3U99_RS24075	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
G3U99_RS24080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G3U99_RS24085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G3U99_RS24090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G3U99_RS24115	COG2827	Endonuclease containing a URI domain
G3U99_RS24130	COG0784	Response regulator, receiver
G3U99_RS24130	COG5002	protein histidine kinase activity
G3U99_RS24160	COG1289	transmembrane transporter activity
G3U99_RS24165	COG0210	DNA helicase
G3U99_RS24185	COG0484	heat shock protein binding
G3U99_RS24195	COG3300	MHYT domain
G3U99_RS24195	COG5001	Diguanylate cyclase
G3U99_RS24200	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G3U99_RS24210	COG4181	ATPase activity
G3U99_RS24215	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G3U99_RS24220	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
G3U99_RS24225	COG1984	allophanate hydrolase subunit 2
G3U99_RS24235	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G3U99_RS24240	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G3U99_RS24260	COG0243	molybdopterin cofactor binding
G3U99_RS24270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G3U99_RS24275	COG3850	Histidine kinase
G3U99_RS24280	COG2197	response regulator
G3U99_RS24285	COG3069	C4-dicarboxylate transmembrane transporter activity
G3U99_RS24305	COG3038	cytochrome b561
G3U99_RS24310	COG2353	YceI-like domain
G3U99_RS24315	COG2116	formate transmembrane transporter activity
G3U99_RS24320	COG0583	DNA-binding transcription factor activity
G3U99_RS24330	COG3593	DNA synthesis involved in DNA repair
G3U99_RS24335	COG0737	Belongs to the 5'-nucleotidase family
G3U99_RS24365	COG1605	Chorismate mutase
G3U99_RS24370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G3U99_RS24390	COG2050	protein possibly involved in aromatic compounds catabolism
G3U99_RS24415	COG0583	DNA-binding transcription factor activity
G3U99_RS24420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G3U99_RS24420	COG0045	succinate-CoA ligase (ADP-forming) activity
G3U99_RS24420	COG1042	CoA-binding domain protein
G3U99_RS24425	COG3266	domain, Protein
G3U99_RS24430	COG1181	Belongs to the D-alanine--D-alanine ligase family
G3U99_RS24445	COG0023	Translation Initiation Factor
G3U99_RS24580	COG3140	Belongs to the UPF0181 family
G3U99_RS24595	COG0745	RESPONSE REGULATOR receiver
G3U99_RS24605	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
G3U99_RS24610	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
G3U99_RS24625	COG3706	GGDEF domain
G3U99_RS24630	COG2203	Gaf domain
G3U99_RS24630	COG3706	GGDEF domain
G3U99_RS24630	COG4251	negative regulation of phosphorylation
G3U99_RS24630	COG5001	Diguanylate cyclase
G3U99_RS24640	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G3U99_RS24645	COG4149	molybdate abc transporter
G3U99_RS24650	COG0725	ABC transporter, periplasmic molybdate-binding protein
G3U99_RS24655	COG1492	cobalamin metabolic process
G3U99_RS24670	COG1609	Transcriptional regulator
G3U99_RS24675	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_RS24675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G3U99_RS24680	COG1105	Belongs to the carbohydrate kinase PfkB family
G3U99_RS24685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_RS24685	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
G3U99_RS24685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G3U99_RS24690	COG3706	GGDEF domain
G3U99_RS24695	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G3U99_RS24700	COG2207	Transcriptional regulator
G3U99_RS24705	COG1979	alcohol dehydrogenase
G3U99_RS24720	COG2198	Histidine kinase
G3U99_RS24720	COG0784	Response regulator, receiver
G3U99_RS24720	COG2205	protein histidine kinase activity
G3U99_RS24725	COG1879	ABC-type sugar transport system periplasmic component
G3U99_RS24730	COG1803	Methylglyoxal synthase
G3U99_RS24735	COG2188	Transcriptional regulator
G3U99_RS24745	COG1263	PTS System
G3U99_RS24745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G3U99_RS24750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_RS24755	COG0800	Aldolase
G3U99_RS24765	COG0546	phosphoglycolate phosphatase activity
G3U99_RS24780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G3U99_RS24785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G3U99_RS24795	COG0583	DNA-binding transcription factor activity
G3U99_RS24800	COG3048	D-serine ammonia-lyase activity
G3U99_RS24810	COG0346	lactoylglutathione lyase activity
G3U99_RS24825	COG1214	PFAM Peptidase M22, glycoprotease
G3U99_RS24825	COG0456	acetyltransferase
G3U99_RS24855	COG0513	Belongs to the DEAD box helicase family
G3U99_RS24865	COG0814	amino acid
G3U99_RS24870	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3U99_RS24870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G3U99_RS24880	COG0513	Belongs to the DEAD box helicase family
G3U99_RS24895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G3U99_RS24905	COG2897	thiosulfate sulfurtransferase activity
G3U99_RS24930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G3U99_RS24940	COG1522	sequence-specific DNA binding
G3U99_RS24950	COG0006	proline dipeptidase activity
G3U99_RS24955	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G3U99_RS24960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G3U99_RS24965	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G3U99_RS24970	COG1473	amidohydrolase
G3U99_RS24980	COG1522	sequence-specific DNA binding
G3U99_RS25000	COG2199	diguanylate cyclase activity
G3U99_RS25020	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G3U99_RS25030	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G3U99_RS25035	COG0523	cobalamin synthesis protein
G3U99_RS25040	COG0038	chloride channel
G3U99_RS25050	COG0156	8-amino-7-oxononanoate synthase activity
G3U99_RS25055	COG0784	Response regulator, receiver
G3U99_RS25055	COG2205	protein histidine kinase activity
G3U99_RS25060	COG0419	ATPase involved in DNA repair
G3U99_RS25070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G3U99_RS25085	COG1192	Involved in chromosome partitioning
G3U99_RS25145	COG0745	RESPONSE REGULATOR receiver
G3U99_RS25150	COG2205	protein histidine kinase activity
G3U99_RS25170	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G3U99_RS25245	COG0671	phosphoesterase, PA-phosphatase related
G3U99_RS25270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G3U99_RS25290	COG2986	histidine ammonia-lyase
G3U99_RS25300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3U99_RS25305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3U99_RS25330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G3U99_RS25335	COG2814	Major facilitator Superfamily
G3U99_RS25350	COG0583	DNA-binding transcription factor activity
G3U99_RS25360	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G3U99_RS25380	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G3U99_RS25420	COG0583	DNA-binding transcription factor activity
G3U99_RS25425	COG1028	Short-chain dehydrogenase reductase Sdr
G3U99_RS25485	COG0384	phenazine biosynthesis protein PhzF
G3U99_RS25605	COG0251	oxidation-reduction process
G3U99_RS25615	COG0583	DNA-binding transcription factor activity
G3U99_RS25635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G3U99_RS25695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G3U99_RS25695	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
G3U99_RS25705	COG0583	DNA-binding transcription factor activity
G3U99_RS25730	COG0625	glutathione transferase activity
G3U99_RS25735	COG0583	DNA-binding transcription factor activity
G3U99_RS25760	COG2207	Transcriptional regulator
G3U99_RS25760	COG1917	Cupin 2, conserved barrel domain protein
G3U99_RS25770	COG4608	Belongs to the ABC transporter superfamily
G3U99_RS25775	COG0444	Belongs to the ABC transporter superfamily
G3U99_RS25780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G3U99_RS25800	COG1609	Transcriptional regulator
G3U99_RS25810	COG4580	involved in the transport of maltose and maltodextrins
G3U99_RS25820	COG1472	Belongs to the glycosyl hydrolase 3 family
G3U99_RS25840	COG1609	Transcriptional regulator
G3U99_RS25850	COG4260	virion core protein, lumpy skin disease virus
G3U99_RS25880	COG1335	isochorismatase
G3U99_RS25885	COG2169	Transcriptional regulator
G3U99_RS25915	COG2267	carboxylic ester hydrolase activity
G3U99_RS25955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G3U99_RS25965	COG4251	negative regulation of phosphorylation
G3U99_RS25965	COG3706	GGDEF domain
G3U99_RS25965	COG2203	Gaf domain
G3U99_RS25965	COG5001	Diguanylate cyclase
G3U99_RS26000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G3U99_RS26045	COG2026	Addiction module toxin, RelE StbE family
G3U99_RS26085	COG1280	lysine exporter protein (LysE YggA)
G3U99_RS26180	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G3U99_RS26185	COG3434	signal transduction protein containing EAL and modified HD-GYP domains