locus-tag	class	description
JV59_RS00010	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JV59_RS00025	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JV59_RS00025	COG0165	Argininosuccinate lyase
JV59_RS00035	COG0251	oxidation-reduction process
JV59_RS00045	COG0678	peroxiredoxin activity
JV59_RS00045	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JV59_RS00055	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JV59_RS00090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JV59_RS00100	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JV59_RS00105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JV59_RS00110	COG0546	phosphoglycolate phosphatase activity
JV59_RS00115	COG0180	Tryptophanyl-tRNA synthetase
JV59_RS00120	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JV59_RS00125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JV59_RS00130	COG2205	protein histidine kinase activity
JV59_RS00135	COG0745	RESPONSE REGULATOR receiver
JV59_RS00140	COG3678	ATP-independent chaperone mediated protein folding
JV59_RS00145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JV59_RS00150	COG0205	6-phosphofructokinase activity
JV59_RS00155	COG1285	pathogenesis
JV59_RS00165	COG1509	lysine 2,3-aminomutase activity
JV59_RS00170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JV59_RS00175	COG1575	Belongs to the MenA family. Type 1 subfamily
JV59_RS00180	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JV59_RS00185	COG0534	Mate efflux family protein
JV59_RS00190	COG0149	triose-phosphate isomerase activity
JV59_RS00205	COG1072	(Pantothenic acid kinase))
JV59_RS00230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JV59_RS00240	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JV59_RS00245	COG0250	Participates in transcription elongation, termination and antitermination
JV59_RS00260	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JV59_RS00270	COG0085	RNA polymerase activity
JV59_RS00280	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
JV59_RS00305	COG4942	peptidase
JV59_RS00310	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JV59_RS00320	COG0840	transmembrane signaling receptor activity
JV59_RS00325	COG0471	metal ion transport
JV59_RS00325	COG0490	domain, Protein
JV59_RS00335	COG1162	GTPase activity
JV59_RS00340	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JV59_RS00375	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JV59_RS00380	COG0802	atpase or kinase
JV59_RS00390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JV59_RS00405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JV59_RS00410	COG0330	HflC and HflK could
JV59_RS00415	COG0330	HflC and HflK could
JV59_RS00420	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
JV59_RS00425	COG2900	Belongs to the SlyX family
JV59_RS00435	COG0545	Peptidyl-prolyl cis-trans isomerase
JV59_RS00440	COG2964	Protein conserved in bacteria
JV59_RS00450	COG2923	Belongs to the DsrF TusC family
JV59_RS00465	COG0049	tRNA binding
JV59_RS00470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JV59_RS00475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JV59_RS00480	COG2906	2 iron, 2 sulfur cluster binding
JV59_RS00490	COG0360	Binds together with S18 to 16S ribosomal RNA
JV59_RS00510	COG0305	Participates in initiation and elongation during chromosome replication
JV59_RS00515	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JV59_RS00520	COG0432	Pfam Uncharacterised protein family UPF0047
JV59_RS00545	COG1136	(ABC) transporter
JV59_RS00560	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
JV59_RS00570	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JV59_RS00575	COG0729	surface antigen
JV59_RS00585	COG2105	PFAM AIG2 family protein
JV59_RS00595	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JV59_RS00605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JV59_RS00610	COG0163	prenyltransferase activity
JV59_RS00615	COG4143	(ABC) transporter
JV59_RS00620	COG1178	ABC-type Fe3 transport system permease component
JV59_RS00625	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JV59_RS00630	COG3028	Belongs to the UPF0307 family
JV59_RS00635	COG0312	modulator of DNA gyrase
JV59_RS00640	COG0527	aspartate kinase activity
JV59_RS00645	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JV59_RS00670	COG0629	single-stranded DNA binding
JV59_RS00675	COG2200	EAL domain
JV59_RS00675	COG2199	diguanylate cyclase activity
JV59_RS00700	COG3409	Peptidoglycan-binding domain 1 protein
JV59_RS00700	COG3267	Type II secretory pathway component ExeA
JV59_RS00710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JV59_RS00715	COG1459	type II secretion system
JV59_RS00725	COG2165	general secretion pathway protein
JV59_RS00730	COG2165	general secretion pathway protein
JV59_RS00760	COG1077	Cell shape determining protein MreB Mrl
JV59_RS00765	COG1792	Involved in formation and maintenance of cell shape
JV59_RS00770	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JV59_RS00775	COG0424	maF-like protein
JV59_RS00785	COG3164	Protein of unknown function
JV59_RS00790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JV59_RS00795	COG0312	modulator of DNA gyrase
JV59_RS00850	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
JV59_RS00865	COG2066	Belongs to the glutaminase family
JV59_RS00870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JV59_RS00875	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JV59_RS01010	COG0762	integral membrane protein
JV59_RS01015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JV59_RS01020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JV59_RS01035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JV59_RS01040	COG1678	Uncharacterized ACR, COG1678
JV59_RS01045	COG0189	ligase activity
JV59_RS01050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JV59_RS01055	COG2356	endonuclease I
JV59_RS01060	COG3091	SprT-like family
JV59_RS01070	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JV59_RS01075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JV59_RS01080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JV59_RS01090	COG0191	fructose-bisphosphate aldolase activity
JV59_RS01095	COG0668	transmembrane transport
JV59_RS01100	COG0442	prolyl-tRNA aminoacylation
JV59_RS01110	COG0583	DNA-binding transcription factor activity
JV59_RS01130	COG0469	pyruvate kinase activity
JV59_RS01135	COG1349	DNA-binding transcription factor activity
JV59_RS01140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JV59_RS01145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JV59_RS01150	COG3722	fumarate hydratase activity
JV59_RS01155	COG0246	Mannitol dehydrogenase
JV59_RS01160	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_RS01160	COG2213	PTS system mannitol-specific
JV59_RS01165	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JV59_RS01175	COG0142	geranyltranstransferase activity
JV59_RS01180	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JV59_RS01190	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JV59_RS01200	COG3610	response to peptide
JV59_RS01205	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JV59_RS01210	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JV59_RS01220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JV59_RS01230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JV59_RS01235	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JV59_RS01240	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JV59_RS01245	COG0582	viral genome integration into host DNA
JV59_RS01285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JV59_RS01305	COG0358	DNA primase activity
JV59_RS01310	COG1610	YqeY-like protein
JV59_RS01315	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JV59_RS01320	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JV59_RS01325	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JV59_RS01330	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JV59_RS01335	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JV59_RS01340	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JV59_RS01345	COG1968	undecaprenyl-diphosphatase activity
JV59_RS01350	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JV59_RS01355	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JV59_RS01365	COG0585	pseudouridine synthase activity
JV59_RS01370	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JV59_RS01380	COG1388	LysM domain
JV59_RS01380	COG4942	peptidase
JV59_RS01385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JV59_RS01390	COG4536	flavin adenine dinucleotide binding
JV59_RS01395	COG4137	Cytochrome C assembly protein
JV59_RS01400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JV59_RS01405	COG0228	four-way junction DNA binding
JV59_RS01415	COG0336	Belongs to the RNA methyltransferase TrmD family
JV59_RS01425	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JV59_RS01430	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
JV59_RS01435	COG0237	dephospho-CoA kinase activity
JV59_RS01445	COG1459	type II secretion system
JV59_RS01450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JV59_RS01455	COG4969	Belongs to the N-Me-Phe pilin family
JV59_RS01460	COG0157	Belongs to the NadC ModD family
JV59_RS01465	COG3023	N-Acetylmuramoyl-L-alanine amidase
JV59_RS01475	COG4974	Belongs to the 'phage' integrase family
JV59_RS01480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JV59_RS01485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JV59_RS01490	COG2186	Transcriptional regulator
JV59_RS01495	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JV59_RS01500	COG0508	dehydrogenase complex catalyzes the overall conversion of
JV59_RS01505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JV59_RS01520	COG0288	reversible hydration of carbon dioxide
JV59_RS01525	COG0659	secondary active sulfate transmembrane transporter activity
JV59_RS01530	COG1131	(ABC) transporter
JV59_RS01535	COG0842	Transport permease protein
JV59_RS01545	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JV59_RS01550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JV59_RS01565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JV59_RS01575	COG1643	Atp-dependent helicase
JV59_RS01580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JV59_RS01585	COG1752	Esterase of the alpha-beta hydrolase superfamily
JV59_RS01590	COG1049	propionate catabolic process, 2-methylcitrate cycle
JV59_RS01605	COG0004	ammonium transporteR
JV59_RS01610	COG1840	ABC-type Fe3 transport system, periplasmic component
JV59_RS01620	COG3842	ATPase activity
JV59_RS01625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JV59_RS01640	COG2971	BadF BadG BcrA BcrD
JV59_RS01650	COG4608	Belongs to the ABC transporter superfamily
JV59_RS01655	COG0444	Belongs to the ABC transporter superfamily
JV59_RS01670	COG0747	negative chemotaxis
JV59_RS01675	COG2205	protein histidine kinase activity
JV59_RS01675	COG0784	Response regulator, receiver
JV59_RS01680	COG2813	Specifically methylates the guanine in position
JV59_RS01685	COG0628	permease
JV59_RS01695	COG0316	Belongs to the HesB IscA family
JV59_RS01710	COG0739	heme binding
JV59_RS01715	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JV59_RS01725	COG2027	D-alanyl-D-alanine carboxypeptidase
JV59_RS01730	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JV59_RS01735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JV59_RS01740	COG1534	Rna-binding protein
JV59_RS01745	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JV59_RS01750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JV59_RS01755	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JV59_RS01785	COG0513	Belongs to the DEAD box helicase family
JV59_RS01800	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JV59_RS01805	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JV59_RS01810	COG0826	peptidase U32
JV59_RS01815	COG0826	peptidase U32
JV59_RS01825	COG3154	lipid carrier protein
JV59_RS01830	COG3153	acetyltransferase
JV59_RS01835	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JV59_RS01850	COG0779	Required for maturation of 30S ribosomal subunits
JV59_RS01855	COG0195	Participates in both transcription termination and antitermination
JV59_RS01880	COG0493	'glutamate synthase
JV59_RS01885	COG0069	glutamate synthase activity
JV59_RS01885	COG0070	glutamate synthase
JV59_RS01885	COG0067	glutamate synthase
JV59_RS01895	COG0067	glutamate synthase
JV59_RS01895	COG0069	glutamate synthase activity
JV59_RS01895	COG0070	glutamate synthase
JV59_RS01900	COG1242	4 iron, 4 sulfur cluster binding
JV59_RS01905	COG5001	Diguanylate cyclase
JV59_RS01905	COG4251	negative regulation of phosphorylation
JV59_RS01905	COG3706	GGDEF domain
JV59_RS01905	COG2203	Gaf domain
JV59_RS01910	COG0784	Response regulator, receiver
JV59_RS01910	COG5002	protein histidine kinase activity
JV59_RS01910	COG2198	Histidine kinase
JV59_RS01920	COG1538	Outer membrane efflux protein
JV59_RS01925	COG0494	nUDIX hydrolase
JV59_RS01930	COG3151	Protein conserved in bacteria
JV59_RS01940	COG3150	esterase
JV59_RS01955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JV59_RS01960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JV59_RS01965	COG3105	Protein conserved in bacteria
JV59_RS01970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JV59_RS01985	COG0723	plastoquinol--plastocyanin reductase activity
JV59_RS01990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JV59_RS01995	COG2857	Cytochrome c1
JV59_RS02000	COG0625	glutathione transferase activity
JV59_RS02005	COG2969	positive regulation of protein catabolic process
JV59_RS02015	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JV59_RS02030	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JV59_RS02040	COG3116	cell division
JV59_RS02045	COG0768	penicillin binding
JV59_RS02050	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JV59_RS02055	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JV59_RS02065	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JV59_RS02070	COG0772	Belongs to the SEDS family
JV59_RS02085	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JV59_RS02090	COG0849	cell division
JV59_RS02095	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JV59_RS02100	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JV59_RS02105	COG0653	protein targeting
JV59_RS02110	COG0494	nUDIX hydrolase
JV59_RS02120	COG0505	Belongs to the CarA family
JV59_RS02130	COG0730	response to heat
JV59_RS02135	COG0583	DNA-binding transcription factor activity
JV59_RS02140	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
JV59_RS02145	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JV59_RS02150	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JV59_RS02165	COG1115	amino acid carrier protein
JV59_RS02170	COG3022	response to hydroperoxide
JV59_RS02175	COG0084	hydrolase, TatD family'
JV59_RS02180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JV59_RS02195	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JV59_RS02200	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JV59_RS02205	COG0813	purine-nucleoside phosphorylase activity
JV59_RS02215	COG0560	Phosphoserine phosphatase
JV59_RS02225	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JV59_RS02230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JV59_RS02235	COG0693	protein deglycase activity
JV59_RS02240	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JV59_RS02245	COG3248	Nucleoside-binding outer membrane protein
JV59_RS02255	COG1595	DNA-templated transcription, initiation
JV59_RS02270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JV59_RS02280	COG2813	Specifically methylates the guanine in position
JV59_RS02285	COG0271	Belongs to the BolA IbaG family
JV59_RS02290	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JV59_RS02295	COG1805	sodium ion transport
JV59_RS02310	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JV59_RS02315	COG2871	sodium ion transport
JV59_RS02320	COG1477	protein flavinylation
JV59_RS02335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JV59_RS02340	COG0514	ATP-dependent DNA helicase (RecQ)
JV59_RS02345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JV59_RS02360	COG0733	neurotransmitter:sodium symporter activity
JV59_RS02370	COG0189	ligase activity
JV59_RS02375	COG4067	protein conserved in archaea
JV59_RS02375	COG0189	ligase activity
JV59_RS02380	COG2195	Cleaves the N-terminal amino acid of tripeptides
JV59_RS02385	COG2252	PERMEase
JV59_RS02390	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JV59_RS02395	COG1073	alpha beta
JV59_RS02405	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JV59_RS02410	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JV59_RS02415	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JV59_RS02420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JV59_RS02420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JV59_RS02440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JV59_RS02445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JV59_RS02450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JV59_RS02465	COG0024	Methionine aminopeptidase
JV59_RS02470	COG0052	Belongs to the universal ribosomal protein uS2 family
JV59_RS02475	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JV59_RS02480	COG0528	UMP kinase activity
JV59_RS02485	COG0233	cytoplasmic translational termination
JV59_RS02490	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JV59_RS02495	COG0575	Belongs to the CDS family
JV59_RS02505	COG0750	zinc metalloprotease
JV59_RS02510	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JV59_RS02515	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
JV59_RS02520	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JV59_RS02525	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JV59_RS02540	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JV59_RS02545	COG0587	DNA-directed DNA polymerase activity
JV59_RS02550	COG0825	malonyl-CoA metabolic process
JV59_RS02565	COG0347	Belongs to the P(II) protein family
JV59_RS02570	COG3021	interspecies interaction between organisms
JV59_RS02580	COG1388	LysM domain
JV59_RS02580	COG0741	lytic transglycosylase activity
JV59_RS02585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JV59_RS02590	COG2226	methyltransferase
JV59_RS02595	COG0328	RNA-DNA hybrid ribonuclease activity
JV59_RS02610	COG1960	acyl-CoA dehydrogenase activity
JV59_RS02615	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JV59_RS02620	COG0121	glutamine amidotransferase
JV59_RS02630	COG1720	tRNA m6t6A37 methyltransferase activity
JV59_RS02635	COG0254	rRNA binding
JV59_RS02645	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JV59_RS02655	COG1464	Belongs to the NlpA lipoprotein family
JV59_RS02660	COG2011	ABC-type metal ion transport system permease component
JV59_RS02665	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JV59_RS02670	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JV59_RS02680	COG1609	Transcriptional regulator
JV59_RS02685	COG1263	PTS System
JV59_RS02685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JV59_RS02690	COG0366	Alpha amylase catalytic
JV59_RS02710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_RS02715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_RS02740	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JV59_RS02750	COG2921	Belongs to the UPF0250 family
JV59_RS02755	COG1686	Belongs to the peptidase S11 family
JV59_RS02760	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JV59_RS02765	COG0772	Belongs to the SEDS family
JV59_RS02770	COG0768	penicillin binding
JV59_RS02775	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JV59_RS02780	COG0799	negative regulation of ribosome biogenesis
JV59_RS02785	COG1466	dna polymerase III delta subunit
JV59_RS02790	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
JV59_RS02795	COG0495	leucyl-tRNA aminoacylation
JV59_RS02800	COG2888	peptidyl-tyrosine sulfation
JV59_RS02805	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JV59_RS02810	COG4535	Mg2 and Co2 transporter CorC
JV59_RS02815	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JV59_RS02820	COG1702	phosphate starvation-inducible protein PhoH
JV59_RS02830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JV59_RS02835	COG2190	(PTS) system
JV59_RS02840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JV59_RS02845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_RS02850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JV59_RS02855	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
JV59_RS02860	COG3115	cell septum assembly
JV59_RS02865	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JV59_RS02885	COG0330	HflC and HflK could
JV59_RS02890	COG3118	belongs to the thioredoxin family
JV59_RS02895	COG0300	oxidoreductase activity
JV59_RS02900	COG1090	epimerase
JV59_RS02925	COG0622	Phosphoesterase
JV59_RS02945	COG3710	Transcriptional regulator
JV59_RS02950	COG0326	Molecular chaperone. Has ATPase activity
JV59_RS02960	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JV59_RS02980	COG2217	Heavy metal translocating P-type atpase
JV59_RS02980	COG2608	mercury ion transmembrane transporter activity
JV59_RS03030	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JV59_RS03070	COG2747	anti-sigma28 factor FlgM
JV59_RS03080	COG0784	Response regulator, receiver
JV59_RS03080	COG0835	chemotaxis
JV59_RS03085	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JV59_RS03090	COG1815	bacterial-type flagellum-dependent cell motility
JV59_RS03110	COG4787	bacterial-type flagellum-dependent cell motility
JV59_RS03120	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JV59_RS03125	COG1706	bacterial-type flagellum-dependent cell motility
JV59_RS03130	COG1705	Flagellar rod assembly protein muramidase FlgJ
JV59_RS03130	COG3951	Flagellar rod assembly protein muramidase FlgJ
JV59_RS03140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JV59_RS03145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JV59_RS03150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JV59_RS03205	COG0012	GTP binding
JV59_RS03215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JV59_RS03220	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JV59_RS03240	COG2890	protein-(glutamine-N5) methyltransferase activity
JV59_RS03250	COG2912	Transglutaminase-like superfamily
JV59_RS03255	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JV59_RS03265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JV59_RS03270	COG2233	PERMEase
JV59_RS03290	COG1393	Belongs to the ArsC family
JV59_RS03295	COG4783	chaperone-mediated protein folding
JV59_RS03315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JV59_RS03320	COG2716	regulation of RNA biosynthetic process
JV59_RS03330	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
JV59_RS03335	COG2056	Na+-H+ antiporter family
JV59_RS03355	COG0346	lactoylglutathione lyase activity
JV59_RS03360	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JV59_RS03365	COG4660	Part of a membrane complex involved in electron transport
JV59_RS03370	COG4659	FMN binding
JV59_RS03375	COG4658	electron transport chain
JV59_RS03380	COG4656	Part of a membrane complex involved in electron transport
JV59_RS03390	COG4657	Part of a membrane complex involved in electron transport
JV59_RS03395	COG1388	LysM domain
JV59_RS03395	COG0741	lytic transglycosylase activity
JV59_RS03415	COG1815	bacterial-type flagellum-dependent cell motility
JV59_RS03420	COG1558	bacterial-type flagellum-dependent cell motility
JV59_RS03430	COG1749	Flagellar hook protein flgE
JV59_RS03435	COG4787	bacterial-type flagellum-dependent cell motility
JV59_RS03440	COG4786	Flagellar basal body rod
JV59_RS03445	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JV59_RS03450	COG1706	bacterial-type flagellum-dependent cell motility
JV59_RS03480	COG1360	Flagellar Motor Protein
JV59_RS03485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JV59_RS03490	COG1191	sigma factor activity
JV59_RS03495	COG1580	Controls the rotational direction of flagella during chemotaxis
JV59_RS03510	COG1516	flagellar protein fliS
JV59_RS03515	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JV59_RS03520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JV59_RS03535	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JV59_RS03545	COG1987	bacterial-type flagellum assembly
JV59_RS03565	COG2885	chlorophyll binding
JV59_RS03610	COG0739	heme binding
JV59_RS03620	COG0556	nucleotide-excision repair
JV59_RS03630	COG2198	Histidine kinase
JV59_RS03635	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JV59_RS03640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JV59_RS03645	COG0521	Mo-molybdopterin cofactor biosynthetic process
JV59_RS03655	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JV59_RS03660	COG0314	molybdopterin synthase activity
JV59_RS03665	COG3706	GGDEF domain
JV59_RS03675	COG0617	tRNA 3'-terminal CCA addition
JV59_RS03675	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JV59_RS03675	COG0517	IMP dehydrogenase activity
JV59_RS03715	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JV59_RS03715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JV59_RS03720	COG0489	protein tyrosine kinase activity
JV59_RS03725	COG0572	uridine kinase
JV59_RS03730	COG2982	Protein involved in outer membrane biogenesis
JV59_RS03740	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
JV59_RS03750	COG0302	gtp cyclohydrolase
JV59_RS03755	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JV59_RS03760	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JV59_RS03760	COG0302	gtp cyclohydrolase
JV59_RS03765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JV59_RS03785	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JV59_RS03790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JV59_RS03800	COG1881	PFAM PEBP family protein
JV59_RS03810	COG0123	including yeast histone deacetylase and acetoin utilization protein
JV59_RS03875	COG3083	sulfuric ester hydrolase activity
JV59_RS03880	COG3082	Protein of unknown function (DUF1414)
JV59_RS03885	COG3081	Nucleoid-associated protein
JV59_RS03905	COG1757	Na H antiporter
JV59_RS03910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JV59_RS03915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JV59_RS03920	COG2095	MarC family integral membrane protein
JV59_RS03925	COG1454	alcohol dehydrogenase
JV59_RS03925	COG1012	belongs to the aldehyde dehydrogenase family
JV59_RS03930	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JV59_RS03940	COG0850	regulation of cytokinetic process
JV59_RS03945	COG3100	YcgL domain-containing protein
JV59_RS03950	COG2951	lytic endotransglycosylase activity
JV59_RS03955	COG0583	DNA-binding transcription factor activity
JV59_RS03960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JV59_RS03970	COG2983	Belongs to the UPF0260 family
JV59_RS03975	COG0668	transmembrane transport
JV59_RS03995	COG1785	Belongs to the alkaline phosphatase family
JV59_RS04010	COG2226	methyltransferase
JV59_RS04040	COG3139	Protein of unknown function (DUF1315)
JV59_RS04045	COG3012	SEC-C Motif Domain Protein
JV59_RS04050	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JV59_RS04055	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JV59_RS04060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JV59_RS04065	COG0215	cysteine-tRNA ligase activity
JV59_RS04070	COG1435	thymidine kinase activity
JV59_RS04075	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JV59_RS04080	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JV59_RS04085	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JV59_RS04095	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JV59_RS04105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JV59_RS04110	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JV59_RS04115	COG0297	glycogen (starch) synthase activity
JV59_RS04135	COG3070	regulator of competence-specific genes
JV59_RS04150	COG0745	RESPONSE REGULATOR receiver
JV59_RS04155	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JV59_RS04160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JV59_RS04170	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
JV59_RS04205	COG0189	ligase activity
JV59_RS04205	COG4067	protein conserved in archaea
JV59_RS04220	COG1801	Protein of unknown function DUF72
JV59_RS04230	COG1187	pseudouridine synthase activity
JV59_RS04240	COG1278	Cold shock
JV59_RS04245	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JV59_RS04250	COG0542	response to heat
JV59_RS04275	COG2116	formate transmembrane transporter activity
JV59_RS04280	COG0390	transport system, permease component
JV59_RS04285	COG4459	periplasmic nitrate reductase
JV59_RS04290	COG3005	denitrification pathway
JV59_RS04295	COG0243	molybdopterin cofactor binding
JV59_RS04310	COG4221	oxidoreductase activity
JV59_RS04330	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JV59_RS04335	COG0840	transmembrane signaling receptor activity
JV59_RS04340	COG0632	four-way junction helicase activity
JV59_RS04345	COG2255	four-way junction helicase activity
JV59_RS04350	COG1271	oxidase subunit
JV59_RS04355	COG1294	oxidase, subunit
JV59_RS04370	COG0824	Thioesterase
JV59_RS04375	COG0811	peptide transport
JV59_RS04390	COG0823	Involved in the tonB-independent uptake of proteins
JV59_RS04395	COG2885	chlorophyll binding
JV59_RS04400	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
JV59_RS04405	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JV59_RS04410	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JV59_RS04430	COG5002	protein histidine kinase activity
JV59_RS04430	COG0784	Response regulator, receiver
JV59_RS04450	COG1902	pentaerythritol trinitrate reductase activity
JV59_RS04455	COG1881	PFAM PEBP family protein
JV59_RS04460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JV59_RS04475	COG1940	carbohydrate kinase activity
JV59_RS04490	COG5002	protein histidine kinase activity
JV59_RS04490	COG3850	Histidine kinase
JV59_RS04495	COG0745	RESPONSE REGULATOR receiver
JV59_RS04500	COG0463	Glycosyl transferase, family 2
JV59_RS04505	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JV59_RS04525	COG1960	acyl-CoA dehydrogenase activity
JV59_RS04530	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JV59_RS04535	COG0708	Exodeoxyribonuclease III
JV59_RS04540	COG0840	transmembrane signaling receptor activity
JV59_RS04560	COG0730	response to heat
JV59_RS04565	COG1199	ATP-dependent helicase activity
JV59_RS04575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JV59_RS04585	COG0156	8-amino-7-oxononanoate synthase activity
JV59_RS04590	COG1073	alpha beta
JV59_RS04590	COG2226	methyltransferase
JV59_RS04595	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JV59_RS04600	COG0501	Belongs to the peptidase M48B family
JV59_RS04625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JV59_RS04635	COG2268	Band 7 protein
JV59_RS04645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JV59_RS04655	COG0482	sulfurtransferase activity
JV59_RS04665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_RS04675	COG1757	Na H antiporter
JV59_RS04685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JV59_RS04695	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JV59_RS04695	COG0131	Imidazoleglycerol-phosphate dehydratase
JV59_RS04700	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JV59_RS04705	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JV59_RS04715	COG0140	phosphoribosyl-ATP diphosphatase activity
JV59_RS04715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JV59_RS04720	COG0217	transcriptional regulatory protein
JV59_RS04730	COG1227	inorganic diphosphatase activity
JV59_RS04745	COG4172	Belongs to the ABC transporter superfamily
JV59_RS04755	COG4171	peptide transport system, permease
JV59_RS04770	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JV59_RS04775	COG1842	Phage shock protein A
JV59_RS04785	COG1983	PspC domain protein
JV59_RS04805	COG2818	Glycosylase
JV59_RS04810	COG5380	lipid catabolic process
JV59_RS04815	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JV59_RS04820	COG0626	cystathionine gamma-synthase activity
JV59_RS04830	COG0733	neurotransmitter:sodium symporter activity
JV59_RS04835	COG0564	pseudouridine synthase activity
JV59_RS04840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JV59_RS04845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JV59_RS04850	COG4136	ATPase activity
JV59_RS04855	COG4135	transport system, permease component
JV59_RS04860	COG4134	Bacterial extracellular solute-binding protein
JV59_RS04870	COG3313	Fe-S protein
JV59_RS04885	COG2350	Protein conserved in bacteria
JV59_RS04920	COG0776	regulation of translation
JV59_RS04930	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JV59_RS04945	COG0417	DNA replication proofreading
JV59_RS04960	COG2197	response regulator
JV59_RS04965	COG0322	excinuclease ABC activity
JV59_RS04995	COG1902	pentaerythritol trinitrate reductase activity
JV59_RS05005	COG2133	pyrroloquinoline quinone binding
JV59_RS05030	COG3706	GGDEF domain
JV59_RS05040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JV59_RS05040	COG0072	phenylalanine-tRNA ligase activity
JV59_RS05090	COG1741	Belongs to the pirin family
JV59_RS05095	COG1335	isochorismatase
JV59_RS05105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JV59_RS05105	COG1263	PTS System
JV59_RS05120	COG1621	beta-fructofuranosidase activity
JV59_RS05140	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JV59_RS05145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_RS05165	COG0583	DNA-binding transcription factor activity
JV59_RS05175	COG0277	FAD linked oxidase domain protein
JV59_RS05185	COG4211	Belongs to the binding-protein-dependent transport system permease family
JV59_RS05190	COG1129	ABC transporter
JV59_RS05200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_RS05205	COG3962	Belongs to the TPP enzyme family
JV59_RS05275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_RS05300	COG0583	DNA-binding transcription factor activity
JV59_RS05310	COG2995	paraquat-inducible protein a
JV59_RS05315	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JV59_RS05315	COG3008	intermembrane lipid transfer
JV59_RS05335	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JV59_RS05340	COG0183	Belongs to the thiolase family
JV59_RS05355	COG0583	DNA-binding transcription factor activity
JV59_RS05360	COG2814	Major facilitator Superfamily
JV59_RS05360	COG0477	Major facilitator Superfamily
JV59_RS05370	COG3962	Belongs to the TPP enzyme family
JV59_RS05375	COG0673	inositol 2-dehydrogenase activity
JV59_RS05380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_RS05410	COG0673	inositol 2-dehydrogenase activity
JV59_RS05420	COG1216	Glycosyl transferase, family 2
JV59_RS05425	COG2223	nitrite transmembrane transporter activity
JV59_RS05435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JV59_RS05445	COG3437	response regulator, receiver
JV59_RS05455	COG2205	protein histidine kinase activity
JV59_RS05455	COG0784	Response regulator, receiver
JV59_RS05465	COG1858	cytochrome C peroxidase
JV59_RS05485	COG0745	RESPONSE REGULATOR receiver
JV59_RS05490	COG0642	Histidine kinase
JV59_RS05500	COG1609	Transcriptional regulator
JV59_RS05505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JV59_RS05520	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JV59_RS05520	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JV59_RS05530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JV59_RS05535	COG1609	Transcriptional regulator
JV59_RS05585	COG0583	DNA-binding transcription factor activity
JV59_RS05630	COG0583	DNA-binding transcription factor activity
JV59_RS05635	COG0352	thiamine-phosphate diphosphorylase activity
JV59_RS05640	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JV59_RS05650	COG1115	amino acid carrier protein
JV59_RS05680	COG5001	Diguanylate cyclase
JV59_RS05680	COG3300	MHYT domain
JV59_RS05735	COG0778	Nitroreductase
JV59_RS05740	COG4580	involved in the transport of maltose and maltodextrins
JV59_RS05760	COG0519	Catalyzes the synthesis of GMP from XMP
JV59_RS05765	COG0242	peptide deformylase activity
JV59_RS05815	COG0307	riboflavin synthase, alpha
JV59_RS05820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JV59_RS05850	COG4221	oxidoreductase activity
JV59_RS05880	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JV59_RS05885	COG0583	DNA-binding transcription factor activity
JV59_RS05895	COG1621	beta-fructofuranosidase activity
JV59_RS05900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JV59_RS05900	COG1263	PTS System
JV59_RS05905	COG2188	Transcriptional regulator
JV59_RS05915	COG0463	Glycosyl transferase, family 2
JV59_RS05935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_RS05940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_RS05980	COG1061	Type III restriction enzyme res subunit
JV59_RS05990	COG2814	Major facilitator Superfamily
JV59_RS06000	COG0702	epimerase
JV59_RS06005	COG0534	Mate efflux family protein
JV59_RS06010	COG1136	(ABC) transporter
JV59_RS06015	COG0577	efflux transmembrane transporter activity
JV59_RS06055	COG0019	diaminopimelate decarboxylase activity
JV59_RS06080	COG0633	Ferredoxin
JV59_RS06085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JV59_RS06095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JV59_RS06105	COG0840	transmembrane signaling receptor activity
JV59_RS06110	COG1328	CTP reductase activity
JV59_RS06115	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JV59_RS06155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JV59_RS06160	COG0745	RESPONSE REGULATOR receiver
JV59_RS06165	COG2205	protein histidine kinase activity
JV59_RS06170	COG4774	siderophore transport
JV59_RS06180	COG0811	peptide transport
JV59_RS06185	COG0811	peptide transport
JV59_RS06190	COG0848	biopolymer transport protein
JV59_RS06210	COG3290	protein histidine kinase activity
JV59_RS06215	COG4565	transcriptional regulatory protein
JV59_RS06235	COG2199	diguanylate cyclase activity
JV59_RS06245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JV59_RS06255	COG2116	formate transmembrane transporter activity
JV59_RS06275	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JV59_RS06295	COG0583	DNA-binding transcription factor activity
JV59_RS06310	COG3969	phosphoadenosine phosphosulfate
JV59_RS06315	COG1475	DNA binding
JV59_RS06325	COG0814	amino acid
JV59_RS06330	COG0745	RESPONSE REGULATOR receiver
JV59_RS06340	COG3713	MltA-interacting MipA family protein
JV59_RS06355	COG2814	Major facilitator Superfamily
JV59_RS06360	COG0583	DNA-binding transcription factor activity
JV59_RS06375	COG3835	regulator
JV59_RS06380	COG1929	Belongs to the glycerate kinase type-1 family
JV59_RS06385	COG2977	Belongs to the P-Pant transferase superfamily
JV59_RS06390	COG1120	ATPase activity
JV59_RS06395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JV59_RS06405	COG4615	Cyclic peptide transporter
JV59_RS06425	COG4774	siderophore transport
JV59_RS06460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JV59_RS06470	COG0297	glycogen (starch) synthase activity
JV59_RS06505	COG0438	transferase activity, transferring glycosyl groups
JV59_RS06515	COG2204	response regulator
JV59_RS06560	COG0534	Mate efflux family protein
JV59_RS06565	COG0307	riboflavin synthase, alpha
JV59_RS06575	COG3001	Fructosamine kinase
JV59_RS06585	COG0791	NLP P60 protein
JV59_RS06590	COG0840	transmembrane signaling receptor activity
JV59_RS06590	COG3290	protein histidine kinase activity
JV59_RS06600	COG3148	PFAM DTW domain containing protein
JV59_RS06635	COG0303	'Molybdopterin
JV59_RS06640	COG0746	molybdenum cofactor guanylyltransferase activity
JV59_RS06645	COG3842	ATPase activity
JV59_RS06650	COG4662	Binding-protein-dependent transport system inner membrane component
JV59_RS06665	COG3852	Histidine kinase
JV59_RS06680	COG1595	DNA-templated transcription, initiation
JV59_RS06690	COG0488	(ABC) transporter
JV59_RS06705	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_RS06715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_RS06720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_RS06725	COG3710	Transcriptional regulator
JV59_RS06735	COG0069	glutamate synthase activity
JV59_RS06755	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JV59_RS06760	COG0583	DNA-binding transcription factor activity
JV59_RS06770	COG0583	DNA-binding transcription factor activity
JV59_RS06795	COG3038	cytochrome b561
JV59_RS06800	COG0840	transmembrane signaling receptor activity
JV59_RS06805	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JV59_RS06835	COG0243	molybdopterin cofactor binding
JV59_RS06835	COG3383	formate dehydrogenase (NAD+) activity
JV59_RS06840	COG0437	4 iron, 4 sulfur cluster binding
JV59_RS06855	COG0004	ammonium transporteR
JV59_RS06860	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JV59_RS06865	COG2199	diguanylate cyclase activity
JV59_RS06870	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JV59_RS06875	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JV59_RS06880	COG1177	transmembrane transport
JV59_RS06890	COG3842	ATPase activity
JV59_RS06915	COG0589	response to stress
JV59_RS06920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JV59_RS06935	COG2217	Heavy metal translocating P-type atpase
JV59_RS06945	COG2010	Cytochrome c
JV59_RS06960	COG3278	Belongs to the heme-copper respiratory oxidase family
JV59_RS07085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JV59_RS07235	COG0840	transmembrane signaling receptor activity
JV59_RS07240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JV59_RS07465	COG1067	ATP-dependent peptidase activity
JV59_RS07470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JV59_RS07485	COG0488	(ABC) transporter
JV59_RS07505	COG0167	dihydroorotate dehydrogenase activity
JV59_RS07520	COG0308	aminopeptidase N
JV59_RS07535	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
JV59_RS07540	COG1956	GAF domain-containing protein
JV59_RS07545	COG1132	(ABC) transporter
JV59_RS07550	COG2995	paraquat-inducible protein a
JV59_RS07555	COG3008	intermembrane lipid transfer
JV59_RS07560	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JV59_RS07560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JV59_RS07585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JV59_RS07600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JV59_RS07605	COG4597	amino acid ABC transporter
JV59_RS07610	COG0765	amino acid transport
JV59_RS07615	COG1126	abc transporter atp-binding protein
JV59_RS07620	COG0670	Belongs to the BI1 family
JV59_RS07625	COG2920	part of a sulfur-relay system
JV59_RS07630	COG1254	Belongs to the acylphosphatase family
JV59_RS07635	COG0840	transmembrane signaling receptor activity
JV59_RS07640	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JV59_RS07670	COG0602	queuosine metabolic process
JV59_RS07675	COG0561	phosphatase activity
JV59_RS07695	COG2828	Protein conserved in bacteria
JV59_RS07705	COG0372	Belongs to the citrate synthase family
JV59_RS07710	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JV59_RS07825	COG0515	serine threonine protein kinase
JV59_RS07830	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JV59_RS07855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_RS07870	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JV59_RS07885	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JV59_RS07890	COG0596	Alpha beta hydrolase
JV59_RS07890	COG0508	dehydrogenase complex catalyzes the overall conversion of
JV59_RS07895	COG3063	Type IV pilus biogenesis stability protein PilW
JV59_RS07910	COG1451	nucleotide metabolic process
JV59_RS07920	COG5002	protein histidine kinase activity
JV59_RS07920	COG0784	Response regulator, receiver
JV59_RS07930	COG1119	ATPase activity
JV59_RS07940	COG2814	Major facilitator Superfamily
JV59_RS07965	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
JV59_RS07970	COG4139	cobalamin transport
JV59_RS07985	COG0406	alpha-ribazole phosphatase activity
JV59_RS07995	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JV59_RS08000	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JV59_RS08005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JV59_RS08010	COG0702	epimerase
JV59_RS08015	COG1823	symporter activity
JV59_RS08140	COG0740	serine-type endopeptidase activity
JV59_RS08265	COG0582	viral genome integration into host DNA
JV59_RS08270	COG2925	Exonuclease
JV59_RS08275	COG1380	Effector of murein hydrolase LrgA
JV59_RS08280	COG1346	cytolysis
JV59_RS08285	COG0295	cytidine deaminase activity
JV59_RS08295	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JV59_RS08320	COG0500	methyltransferase
JV59_RS08340	COG4326	sporulation control protein
JV59_RS08345	COG2188	Transcriptional regulator
JV59_RS08350	COG1228	amidohydrolase
JV59_RS08355	COG0010	Belongs to the arginase family
JV59_RS08365	COG2986	histidine ammonia-lyase
JV59_RS08395	COG2885	chlorophyll binding
JV59_RS08410	COG0625	glutathione transferase activity
JV59_RS08420	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JV59_RS08430	COG2195	Cleaves the N-terminal amino acid of tripeptides
JV59_RS08445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JV59_RS08450	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JV59_RS08465	COG0456	acetyltransferase
JV59_RS08495	COG0454	-acetyltransferase
JV59_RS08550	COG3122	Protein conserved in bacteria
JV59_RS08565	COG3040	lipid binding
JV59_RS08585	COG0456	acetyltransferase
JV59_RS08600	COG2824	Alkylphosphonate utilization operon protein PhnA
JV59_RS08610	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_RS08620	COG0730	response to heat
JV59_RS08645	COG4628	conserved protein (DUF2132)
JV59_RS08650	COG0546	phosphoglycolate phosphatase activity
JV59_RS08725	COG2962	Rard protein
JV59_RS08740	COG0783	Belongs to the Dps family
JV59_RS08745	COG4667	esterase of the alpha-beta hydrolase superfamily
JV59_RS08780	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JV59_RS08795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JV59_RS08800	COG3108	Peptidase M15
JV59_RS08805	COG2989	Protein conserved in bacteria
JV59_RS08830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JV59_RS08840	COG3706	GGDEF domain
JV59_RS08860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JV59_RS08875	COG3106	COG3106 Predicted ATPase
JV59_RS08890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JV59_RS08895	COG2205	protein histidine kinase activity
JV59_RS08895	COG0784	Response regulator, receiver
JV59_RS08905	COG0494	nUDIX hydrolase
JV59_RS08910	COG0814	amino acid
JV59_RS08915	COG1760	l-serine dehydratase
JV59_RS08925	COG0814	amino acid
JV59_RS08940	COG0017	Asparaginyl-tRNA synthetase
JV59_RS08950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JV59_RS08960	COG2770	Histidine kinase
JV59_RS08960	COG3437	response regulator, receiver
JV59_RS08965	COG1448	Aminotransferase
JV59_RS08980	COG1643	Atp-dependent helicase
JV59_RS08985	COG0281	malic enzyme
JV59_RS08995	COG2949	membrane
JV59_RS09005	COG0612	Peptidase, M16
JV59_RS09020	COG2175	clavaminate synthase activity
JV59_RS09035	COG0492	ferredoxin-NADP+ reductase activity
JV59_RS09040	COG4988	ABC transporter
JV59_RS09045	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JV59_RS09050	COG2814	Major facilitator Superfamily
JV59_RS09060	COG0384	phenazine biosynthesis protein PhzF
JV59_RS09065	COG1187	pseudouridine synthase activity
JV59_RS09080	COG0009	L-threonylcarbamoyladenylate synthase
JV59_RS09085	COG0613	PHP domain protein
JV59_RS09095	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JV59_RS09100	COG0512	Glutamine amidotransferase of anthranilate synthase
JV59_RS09105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JV59_RS09110	COG0134	indole-3-glycerol-phosphate synthase activity
JV59_RS09110	COG0135	phosphoribosylanthranilate isomerase activity
JV59_RS09120	COG0159	tryptophan synthase activity
JV59_RS09125	COG1301	dicarboxylic acid transport
JV59_RS09150	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JV59_RS09255	COG1643	Atp-dependent helicase
JV59_RS09300	COG0443	Heat shock 70 kDa protein
JV59_RS09310	COG1858	cytochrome C peroxidase
JV59_RS09355	COG3152	Membrane
JV59_RS09370	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JV59_RS09375	COG0840	transmembrane signaling receptor activity
JV59_RS09395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JV59_RS09400	COG0673	inositol 2-dehydrogenase activity
JV59_RS09410	COG0583	DNA-binding transcription factor activity
JV59_RS09420	COG1846	Transcriptional regulator
JV59_RS09425	COG1764	response to oxidative stress
JV59_RS09430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JV59_RS09455	COG1032	radical SAM domain protein
JV59_RS09465	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JV59_RS09475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JV59_RS09475	COG4191	Histidine kinase
JV59_RS09490	COG3070	regulator of competence-specific genes
JV59_RS09500	COG2431	L-lysine efflux transmembrane transporter activity
JV59_RS09510	COG0076	glutamate decarboxylase activity
JV59_RS09515	COG1737	Transcriptional regulator
JV59_RS09520	COG1012	belongs to the aldehyde dehydrogenase family
JV59_RS09520	COG1454	alcohol dehydrogenase
JV59_RS09550	COG3646	Phage regulatory protein
JV59_RS09605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JV59_RS09640	COG1882	Formate acetyltransferase
JV59_RS09655	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JV59_RS09665	COG3013	Belongs to the UPF0304 family
JV59_RS09670	COG3713	MltA-interacting MipA family protein
JV59_RS09675	COG2766	serine protein kinase
JV59_RS09680	COG2718	Belongs to the UPF0229 family
JV59_RS09685	COG2719	SpoVR family
JV59_RS09690	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JV59_RS09695	COG2835	tetraacyldisaccharide 4'-kinase activity
JV59_RS09705	COG1132	(ABC) transporter
JV59_RS09710	COG2333	competence protein COMEC
JV59_RS09710	COG0658	competence protein
JV59_RS09720	COG4591	ABC-type transport system involved in lipoprotein release permease component
JV59_RS09725	COG1136	(ABC) transporter
JV59_RS09730	COG4591	ABC-type transport system involved in lipoprotein release permease component
JV59_RS09740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JV59_RS09760	COG1252	NADH dehydrogenase
JV59_RS09790	COG0537	adenosine 5'-monophosphoramidase activity
JV59_RS09805	COG2186	Transcriptional regulator
JV59_RS09810	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JV59_RS09820	COG1674	ftsk spoiiie
JV59_RS09830	COG0686	Belongs to the AlaDH PNT family
JV59_RS09835	COG3092	negative regulation of chromosome organization
JV59_RS09840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JV59_RS09845	COG0857	belongs to the CobB CobQ family
JV59_RS09845	COG0280	phosphate acetyltransferase
JV59_RS09850	COG3706	GGDEF domain
JV59_RS09855	COG0435	Glutathione S-transferase
JV59_RS09865	COG0444	Belongs to the ABC transporter superfamily
JV59_RS09870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JV59_RS09875	COG0601	transmembrane transport
JV59_RS09895	COG3706	GGDEF domain
JV59_RS09910	COG0840	transmembrane signaling receptor activity
JV59_RS09920	COG1404	Belongs to the peptidase S8 family
JV59_RS09925	COG0840	transmembrane signaling receptor activity
JV59_RS09935	COG0330	HflC and HflK could
JV59_RS09955	COG0577	efflux transmembrane transporter activity
JV59_RS09955	COG1136	(ABC) transporter
JV59_RS09960	COG1136	(ABC) transporter
JV59_RS09960	COG0577	efflux transmembrane transporter activity
JV59_RS09965	COG0577	efflux transmembrane transporter activity
JV59_RS09975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_RS09985	COG3227	Zinc metalloprotease (Elastase)
JV59_RS09995	COG1770	oligopeptidase
JV59_RS10000	COG3397	chitin binding
JV59_RS10015	COG1215	transferase activity, transferring glycosyl groups
JV59_RS10020	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JV59_RS10025	COG3876	Protein conserved in bacteria
JV59_RS10030	COG1472	Belongs to the glycosyl hydrolase 3 family
JV59_RS10045	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JV59_RS10045	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JV59_RS10050	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JV59_RS10055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JV59_RS10060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JV59_RS10075	COG2855	membrane
JV59_RS10095	COG0730	response to heat
JV59_RS10100	COG0280	phosphate acetyltransferase
JV59_RS10105	COG1414	Transcriptional regulator
JV59_RS10135	COG3706	GGDEF domain
JV59_RS10150	COG3126	Type III secretion system lipoprotein chaperone (YscW)
JV59_RS10155	COG1946	Acyl-CoA thioesterase
JV59_RS10170	COG1522	sequence-specific DNA binding
JV59_RS10195	COG0477	Major facilitator Superfamily
JV59_RS10200	COG2855	membrane
JV59_RS10220	COG0596	Alpha beta hydrolase
JV59_RS10225	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JV59_RS10230	COG1169	isochorismate synthase
JV59_RS10235	COG0436	Aminotransferase
JV59_RS10240	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
JV59_RS10255	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JV59_RS10260	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JV59_RS10275	COG0513	Belongs to the DEAD box helicase family
JV59_RS10280	COG0616	signal peptide processing
JV59_RS10285	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_RS10305	COG0835	chemotaxis
JV59_RS10305	COG0784	Response regulator, receiver
JV59_RS10310	COG1940	carbohydrate kinase activity
JV59_RS10315	COG0469	pyruvate kinase activity
JV59_RS10320	COG4667	esterase of the alpha-beta hydrolase superfamily
JV59_RS10335	COG0733	neurotransmitter:sodium symporter activity
JV59_RS10345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JV59_RS10345	COG1263	PTS System
JV59_RS10350	COG0084	hydrolase, TatD family'
JV59_RS10355	COG0470	DNA polymerase III
JV59_RS10360	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JV59_RS10365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JV59_RS10370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JV59_RS10395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JV59_RS10405	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JV59_RS10410	COG1399	metal-binding, possibly nucleic acid-binding protein
JV59_RS10415	COG0424	maF-like protein
JV59_RS10420	COG0564	pseudouridine synthase activity
JV59_RS10425	COG1530	ribonuclease E activity
JV59_RS10430	COG0659	secondary active sulfate transmembrane transporter activity
JV59_RS10440	COG0318	PFAM AMP-dependent synthetase and ligase
JV59_RS10445	COG2267	carboxylic ester hydrolase activity
JV59_RS10460	COG1214	PFAM Peptidase M22, glycoprotease
JV59_RS10465	COG1199	ATP-dependent helicase activity
JV59_RS10475	COG0788	formyltetrahydrofolate deformylase activity
JV59_RS10480	COG0446	pyridine nucleotide-disulphide oxidoreductase
JV59_RS10480	COG1902	pentaerythritol trinitrate reductase activity
JV59_RS10485	COG0616	signal peptide processing
JV59_RS10490	COG0252	asparaginase activity
JV59_RS10500	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JV59_RS10505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JV59_RS10515	COG0653	protein targeting
JV59_RS10525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JV59_RS10530	COG3706	GGDEF domain
JV59_RS10540	COG4120	Belongs to the binding-protein-dependent transport system permease family
JV59_RS10575	COG0284	orotidine-5'-phosphate decarboxylase activity
JV59_RS10580	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JV59_RS10585	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
JV59_RS10595	COG0539	negative regulation of cytoplasmic translation
JV59_RS10605	COG1555	photosystem II stabilization
JV59_RS10610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JV59_RS10615	COG0776	regulation of translation
JV59_RS10620	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JV59_RS10645	COG2204	response regulator
JV59_RS10655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JV59_RS10660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JV59_RS10665	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JV59_RS10670	COG3842	ATPase activity
JV59_RS10680	COG1175	transmembrane transport
JV59_RS10685	COG1653	transport
JV59_RS10720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JV59_RS10735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JV59_RS10740	COG2832	Protein of unknown function (DUF454)
JV59_RS10750	COG0745	RESPONSE REGULATOR receiver
JV59_RS10755	COG0583	DNA-binding transcription factor activity
JV59_RS10760	COG0778	Nitroreductase
JV59_RS10770	COG0183	Belongs to the thiolase family
JV59_RS10785	COG2067	long-chain fatty acid transport protein
JV59_RS10790	COG2067	long-chain fatty acid transport protein
JV59_RS10795	COG2853	Lipoprotein
JV59_RS10805	COG4235	cytochrome complex assembly
JV59_RS10805	COG3088	subunit of a heme lyase
JV59_RS10810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JV59_RS10815	COG1138	Cytochrome C-type biogenesis protein
JV59_RS10825	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JV59_RS10830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JV59_RS10835	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JV59_RS10840	COG4133	protoheme IX ABC transporter activity
JV59_RS10850	COG0835	chemotaxis
JV59_RS10860	COG1192	Involved in chromosome partitioning
JV59_RS10865	COG2201	protein-glutamate methylesterase activity
JV59_RS10870	COG2198	Histidine kinase
JV59_RS10870	COG0784	Response regulator, receiver
JV59_RS10870	COG0643	Histidine kinase
JV59_RS10875	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
JV59_RS10905	COG2062	phosphohistidine phosphatase, SixA
JV59_RS10910	COG1025	Belongs to the peptidase M16 family
JV59_RS10915	COG3102	Protein conserved in bacteria
JV59_RS10920	COG0018	arginyl-trna synthetase
JV59_RS10935	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JV59_RS10940	COG1918	ferrous iron import across plasma membrane
JV59_RS10945	COG4977	sequence-specific DNA binding
JV59_RS10950	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
JV59_RS10955	COG1121	(ABC) transporter
JV59_RS10960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JV59_RS10965	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JV59_RS10970	COG1286	toxin biosynthetic process
JV59_RS10975	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
JV59_RS10980	COG0285	dihydrofolate synthase activity
JV59_RS10985	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JV59_RS10990	COG0101	tRNA pseudouridine synthase activity
JV59_RS11000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JV59_RS11005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JV59_RS11010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JV59_RS11040	COG3101	peptidyl-lysine hydroxylation
JV59_RS11045	COG2860	membrane
JV59_RS11055	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JV59_RS11060	COG2890	protein-(glutamine-N5) methyltransferase activity
JV59_RS11075	COG1684	flagellar biosynthetic protein fliR
JV59_RS11080	COG1987	bacterial-type flagellum assembly
JV59_RS11130	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JV59_RS11140	COG1677	Flagellar hook-basal body complex protein FliE
JV59_RS11160	COG1516	flagellar protein fliS
JV59_RS11170	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JV59_RS11180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JV59_RS11195	COG2837	iron assimilation
JV59_RS11205	COG3088	subunit of a heme lyase
JV59_RS11205	COG4235	cytochrome complex assembly
JV59_RS11210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JV59_RS11215	COG1138	Cytochrome C-type biogenesis protein
JV59_RS11220	COG3301	Polysulphide reductase, NrfD
JV59_RS11225	COG0437	4 iron, 4 sulfur cluster binding
JV59_RS11230	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
JV59_RS11235	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
JV59_RS11260	COG1393	Belongs to the ArsC family
JV59_RS11265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JV59_RS11275	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
JV59_RS11285	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JV59_RS11285	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JV59_RS11300	COG1611	Belongs to the LOG family
JV59_RS11315	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
JV59_RS11330	COG0583	DNA-binding transcription factor activity
JV59_RS11335	COG0301	tRNA thio-modification
JV59_RS11335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JV59_RS11345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JV59_RS11350	COG1722	exodeoxyribonuclease VII activity
JV59_RS11355	COG0142	geranyltranstransferase activity
JV59_RS11365	COG0564	pseudouridine synthase activity
JV59_RS11370	COG3098	single-species biofilm formation
JV59_RS11400	COG0508	dehydrogenase complex catalyzes the overall conversion of
JV59_RS11405	COG0567	Dehydrogenase, E1 component
JV59_RS11410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JV59_RS11415	COG1053	succinate dehydrogenase
JV59_RS11420	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JV59_RS11435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JV59_RS11445	COG0033	Phosphoglucomutase
JV59_RS11450	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
JV59_RS11455	COG0596	Alpha beta hydrolase
JV59_RS11480	COG0167	dihydroorotate dehydrogenase activity
JV59_RS11495	COG1263	PTS System
JV59_RS11495	COG2190	(PTS) system
JV59_RS11495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JV59_RS11500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JV59_RS11505	COG1940	carbohydrate kinase activity
JV59_RS11505	COG1846	Transcriptional regulator
JV59_RS11510	COG4651	solute:proton antiporter activity
JV59_RS11510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JV59_RS11515	COG0367	asparagine synthase
JV59_RS11520	COG3104	oligopeptide transport
JV59_RS11545	COG2840	Smr protein MutS2
JV59_RS11550	COG1187	pseudouridine synthase activity
JV59_RS11555	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JV59_RS11560	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JV59_RS11565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JV59_RS11595	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JV59_RS11605	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JV59_RS11625	COG4970	Tfp pilus assembly protein FimT
JV59_RS11640	COG0443	Heat shock 70 kDa protein
JV59_RS11645	COG1301	dicarboxylic acid transport
JV59_RS11650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JV59_RS11655	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JV59_RS11660	COG0497	DNA recombination
JV59_RS11665	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JV59_RS11670	COG2914	Belongs to the UPF0125 (RnfH) family
JV59_RS11675	COG2867	negative regulation of translational initiation
JV59_RS11690	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JV59_RS11730	COG0668	transmembrane transport
JV59_RS11735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JV59_RS11755	COG0204	Acyl-transferase
JV59_RS11760	COG0835	chemotaxis
JV59_RS11760	COG0784	Response regulator, receiver
JV59_RS11785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JV59_RS11790	COG1115	amino acid carrier protein
JV59_RS11795	COG1584	GPR1 FUN34 yaaH family protein
JV59_RS11810	COG0516	GMP reductase activity
JV59_RS11810	COG0517	IMP dehydrogenase activity
JV59_RS11825	COG2203	Gaf domain
JV59_RS11825	COG2199	diguanylate cyclase activity
JV59_RS11835	COG1160	GTP binding
JV59_RS11840	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JV59_RS11845	COG2976	Protein conserved in bacteria
JV59_RS11850	COG0124	histidyl-tRNA synthetase
JV59_RS11855	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JV59_RS11860	COG1426	Protein conserved in bacteria
JV59_RS11870	COG2166	iron-sulfur cluster assembly
JV59_RS11875	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JV59_RS11880	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
JV59_RS11900	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JV59_RS11905	COG1074	ATP-dependent DNA helicase activity
JV59_RS11910	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JV59_RS11930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_RS11935	COG1309	transcriptional regulator
JV59_RS11940	COG3141	response to X-ray
JV59_RS11980	COG0704	Plays a role in the regulation of phosphate uptake
JV59_RS11985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JV59_RS11990	COG0581	inorganic phosphate transmembrane transporter activity
JV59_RS11995	COG0573	inorganic phosphate transmembrane transporter activity
JV59_RS12000	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JV59_RS12005	COG0248	Ppx GppA phosphatase
JV59_RS12015	COG5002	protein histidine kinase activity
JV59_RS12020	COG0745	RESPONSE REGULATOR receiver
JV59_RS12030	COG0826	peptidase U32
JV59_RS12035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JV59_RS12055	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JV59_RS12060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JV59_RS12065	COG1862	Preprotein translocase
JV59_RS12075	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JV59_RS12080	COG0517	IMP dehydrogenase activity
JV59_RS12090	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JV59_RS12095	COG0583	DNA-binding transcription factor activity
JV59_RS12100	COG0450	alkyl hydroperoxide reductase
JV59_RS12105	COG2171	N-acyltransferase activity
JV59_RS12115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_RS12125	COG2207	Transcriptional regulator
JV59_RS12130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_RS12130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_RS12130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_RS12140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JV59_RS12150	COG2017	converts alpha-aldose to the beta-anomer
JV59_RS12160	COG1085	galactose-1-phosphate uridylyltransferase
JV59_RS12165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JV59_RS12170	COG1609	Transcriptional regulator
JV59_RS12175	COG3250	beta-galactosidase activity
JV59_RS12180	COG2731	YhcH YjgK YiaL family protein
JV59_RS12185	COG0531	amino acid
JV59_RS12205	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
JV59_RS12205	COG3408	Glycogen debranching enzyme
JV59_RS12215	COG2211	Major facilitator Superfamily
JV59_RS12220	COG1486	melibiose metabolic process
JV59_RS12225	COG2169	Transcriptional regulator
JV59_RS12275	COG4964	Belongs to the GSP D family
JV59_RS12305	COG2169	Transcriptional regulator
JV59_RS12315	COG0583	DNA-binding transcription factor activity
JV59_RS12325	COG0583	DNA-binding transcription factor activity
JV59_RS12330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JV59_RS12340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JV59_RS12345	COG2975	iron-sulfur cluster assembly
JV59_RS12350	COG0633	Ferredoxin
JV59_RS12370	COG0822	iron-sulfur transferase activity
JV59_RS12380	COG1959	2 iron, 2 sulfur cluster binding
JV59_RS12390	COG0483	inositol monophosphate 1-phosphatase activity
JV59_RS12430	COG0542	response to heat
JV59_RS12440	COG0564	pseudouridine synthase activity
JV59_RS12445	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JV59_RS12450	COG0741	lytic transglycosylase activity
JV59_RS12455	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JV59_RS12460	COG1605	Chorismate mutase
JV59_RS12460	COG0077	Prephenate dehydratase
JV59_RS12465	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JV59_RS12470	COG5001	Diguanylate cyclase
JV59_RS12475	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
JV59_RS12480	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
JV59_RS12485	COG0741	lytic transglycosylase activity
JV59_RS12490	COG0488	(ABC) transporter
JV59_RS12500	COG0739	heme binding
JV59_RS12505	COG1605	Chorismate mutase
JV59_RS12505	COG0287	Prephenate dehydrogenase
JV59_RS12515	COG3275	phosphorelay sensor kinase activity
JV59_RS12520	COG3279	Response regulator of the LytR AlgR family
JV59_RS12530	COG1737	Transcriptional regulator
JV59_RS12540	COG2971	BadF BadG BcrA BcrD
JV59_RS12545	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JV59_RS12550	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JV59_RS12560	COG1966	Carbon starvation protein
JV59_RS12565	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JV59_RS12570	COG1047	Peptidyl-prolyl cis-trans
JV59_RS12585	COG0196	riboflavin kinase activity
JV59_RS12590	COG0728	peptidoglycan biosynthetic process
JV59_RS12595	COG0268	Binds directly to 16S ribosomal RNA
JV59_RS12600	COG0640	Transcriptional regulator
JV59_RS12605	COG0583	DNA-binding transcription factor activity
JV59_RS12615	COG1283	sodium-dependent phosphate transmembrane transporter activity
JV59_RS12620	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JV59_RS12625	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JV59_RS12630	COG0730	response to heat
JV59_RS12640	COG0494	nUDIX hydrolase
JV59_RS12645	COG3066	DNA modification
JV59_RS12655	COG0667	Aldo Keto reductase
JV59_RS12665	COG2204	response regulator
JV59_RS12670	COG0534	Mate efflux family protein
JV59_RS12675	COG1846	Transcriptional regulator
JV59_RS12690	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JV59_RS12700	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
JV59_RS12705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JV59_RS12710	COG2860	membrane
JV59_RS12715	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JV59_RS12720	COG0083	homoserine kinase activity
JV59_RS12735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JV59_RS12745	COG0745	RESPONSE REGULATOR receiver
JV59_RS12750	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JV59_RS12750	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JV59_RS12755	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JV59_RS12765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JV59_RS12770	COG3025	triphosphatase activity
JV59_RS12775	COG1392	Phosphate transport regulator
JV59_RS12780	COG0306	phosphate transporter
JV59_RS12785	COG4991	sh3 domain protein
JV59_RS12795	COG3267	Type II secretory pathway component ExeA
JV59_RS12795	COG3409	Peptidoglycan-binding domain 1 protein
JV59_RS12800	COG0617	tRNA 3'-terminal CCA addition
JV59_RS12805	COG0148	phosphopyruvate hydratase activity
JV59_RS12810	COG0148	phosphopyruvate hydratase activity
JV59_RS12815	COG0148	phosphopyruvate hydratase activity
JV59_RS12820	COG0148	phosphopyruvate hydratase activity
JV59_RS12830	COG3956	TIGRFAM MazG family protein
JV59_RS12835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JV59_RS12840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JV59_RS12845	COG2205	protein histidine kinase activity
JV59_RS12845	COG4999	Histidine kinase
JV59_RS12845	COG3850	Histidine kinase
JV59_RS12845	COG3437	response regulator, receiver
JV59_RS12850	COG0736	holo-[acyl-carrier-protein] synthase activity
JV59_RS12855	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JV59_RS12860	COG1381	Involved in DNA repair and RecF pathway recombination
JV59_RS12865	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JV59_RS12880	COG0481	GTPase activity
JV59_RS12885	COG3086	response to oxidative stress
JV59_RS12890	COG3026	antisigma factor binding
JV59_RS12900	COG1595	DNA-templated transcription, initiation
JV59_RS12905	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JV59_RS12935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JV59_RS12940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JV59_RS12945	COG3079	Belongs to the UPF0149 family
JV59_RS12950	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JV59_RS12955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JV59_RS12965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JV59_RS12970	COG2271	Major facilitator Superfamily
JV59_RS12975	COG0584	glycerophosphoryl diester phosphodiesterase
JV59_RS12980	COG0440	acetolactate synthase activity
JV59_RS12985	COG0028	Belongs to the TPP enzyme family
JV59_RS12990	COG1022	Amp-dependent synthetase and ligase
JV59_RS12995	COG0583	DNA-binding transcription factor activity
JV59_RS13015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JV59_RS13020	COG0473	3-isopropylmalate dehydrogenase activity
JV59_RS13030	COG0066	3-isopropylmalate dehydratase activity
JV59_RS13080	COG3437	response regulator, receiver
JV59_RS13100	COG1854	S-ribosylhomocysteine lyase activity
JV59_RS13110	COG2918	glutathione biosynthetic process
JV59_RS13115	COG0612	Peptidase, M16
JV59_RS13120	COG1238	metal cluster binding
JV59_RS13130	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
JV59_RS13135	COG0511	ligase activity, forming carbon-carbon bonds
JV59_RS13135	COG5016	pyruvate
JV59_RS13140	COG3630	sodium ion export across plasma membrane
JV59_RS13190	COG2137	regulation of response to DNA damage stimulus
JV59_RS13195	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JV59_RS13200	COG1546	Belongs to the CinA family
JV59_RS13205	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JV59_RS13210	COG0795	lipopolysaccharide-transporting ATPase activity
JV59_RS13215	COG0795	lipopolysaccharide-transporting ATPase activity
JV59_RS13240	COG4269	membrane
JV59_RS13250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JV59_RS13255	COG0564	pseudouridine synthase activity
JV59_RS13270	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JV59_RS13285	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
JV59_RS13290	COG0251	oxidation-reduction process
JV59_RS13300	COG0039	L-malate dehydrogenase activity
JV59_RS13305	COG1438	arginine binding
JV59_RS13310	COG2358	TRAP transporter, solute receptor (TAXI family
JV59_RS13320	COG0589	response to stress
JV59_RS13340	COG2235	arginine
JV59_RS13345	COG0204	Acyl-transferase
JV59_RS13355	COG5007	Belongs to the BolA IbaG family
JV59_RS13365	COG2854	intermembrane phospholipid transfer
JV59_RS13370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JV59_RS13375	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JV59_RS13380	COG1127	ABC transporter
JV59_RS13395	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JV59_RS13405	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JV59_RS13410	COG1137	ATPase activity
JV59_RS13420	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JV59_RS13425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_RS13430	COG1660	Displays ATPase and GTPase activities
JV59_RS13435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_RS13440	COG2239	Acts as a magnesium transporter
JV59_RS13445	COG1410	methionine synthase
JV59_RS13445	COG0646	methionine synthase
JV59_RS13480	COG0175	sulfate reduction
JV59_RS13485	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JV59_RS13490	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JV59_RS13635	COG3437	response regulator, receiver
JV59_RS13645	COG0735	belongs to the Fur family
JV59_RS13655	COG0529	Catalyzes the synthesis of activated sulfate
JV59_RS13660	COG3273	potassium ion transport
JV59_RS13660	COG0471	metal ion transport
JV59_RS13675	COG1648	precorrin-2 dehydrogenase activity
JV59_RS13675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JV59_RS13680	COG0737	Belongs to the 5'-nucleotidase family
JV59_RS13690	COG2153	protein acetylation
JV59_RS13715	COG0203	ribosomal protein L17
JV59_RS13720	COG0202	RNA polymerase activity
JV59_RS13730	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JV59_RS13735	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JV59_RS13740	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JV59_RS13745	COG0201	protein transport
JV59_RS13750	COG0200	Binds to the 23S rRNA
JV59_RS13755	COG1841	ribosomal large subunit assembly
JV59_RS13770	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JV59_RS13785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JV59_RS13800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JV59_RS13815	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JV59_RS13820	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JV59_RS13825	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JV59_RS13840	COG0088	Forms part of the polypeptide exit tunnel
JV59_RS13845	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JV59_RS13850	COG0051	transcription antitermination factor activity, RNA binding
JV59_RS13855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JV59_RS13860	COG0557	exoribonuclease II activity
JV59_RS13865	COG0402	S-adenosylhomocysteine deaminase activity
JV59_RS13870	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
JV59_RS13875	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JV59_RS13885	COG1047	Peptidyl-prolyl cis-trans
JV59_RS13900	COG2249	NAD(P)H dehydrogenase (quinone) activity
JV59_RS13905	COG0488	(ABC) transporter
JV59_RS13915	COG0429	hydrolase of the alpha beta-hydrolase fold
JV59_RS13920	COG3089	Belongs to the UPF0270 family
JV59_RS13925	COG3954	Phosphoribulokinase
JV59_RS13930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JV59_RS13940	COG1012	belongs to the aldehyde dehydrogenase family
JV59_RS13950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JV59_RS14015	COG1027	Aspartate ammonia-lyase
JV59_RS14020	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JV59_RS14025	COG1288	antiporter activity
JV59_RS14040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JV59_RS14045	COG0540	Belongs to the ATCase OTCase family
JV59_RS14050	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
JV59_RS14055	COG1438	arginine binding
JV59_RS14060	COG4232	protein-disulfide reductase activity
JV59_RS14070	COG2095	MarC family integral membrane protein
JV59_RS14080	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JV59_RS14090	COG0784	Response regulator, receiver
JV59_RS14090	COG2205	protein histidine kinase activity
JV59_RS14095	COG2814	Major facilitator Superfamily
JV59_RS14110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JV59_RS14115	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JV59_RS14120	COG0511	ligase activity, forming carbon-carbon bonds
JV59_RS14125	COG0439	Biotin carboxylase
JV59_RS14130	COG2264	protein methyltransferase activity
JV59_RS14135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JV59_RS14140	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JV59_RS14145	COG2199	diguanylate cyclase activity
JV59_RS14150	COG0789	Transcriptional regulator
JV59_RS14160	COG0151	Belongs to the GarS family
JV59_RS14175	COG1253	flavin adenine dinucleotide binding
JV59_RS14185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JV59_RS14190	COG1573	uracil-dna glycosylase
JV59_RS14195	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JV59_RS14200	COG1695	Transcriptional regulator
JV59_RS14205	COG1045	serine acetyltransferase
JV59_RS14220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JV59_RS14255	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JV59_RS14260	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JV59_RS14265	COG1053	succinate dehydrogenase
JV59_RS14270	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JV59_RS14295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JV59_RS14300	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JV59_RS14305	COG1609	Transcriptional regulator
JV59_RS14310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JV59_RS14320	COG0281	malic enzyme
JV59_RS14325	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
JV59_RS14330	COG0626	cystathionine gamma-synthase activity
JV59_RS14335	COG0527	aspartate kinase activity
JV59_RS14335	COG0460	homoserine dehydrogenase
JV59_RS14340	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JV59_RS14345	COG3074	FtsZ-dependent cytokinesis
JV59_RS14350	COG1494	fructose-1,6-bisphosphatase
JV59_RS14400	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JV59_RS14405	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JV59_RS14405	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JV59_RS14410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JV59_RS14415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JV59_RS14460	COG2226	methyltransferase
JV59_RS14470	COG4310	Domain of unknown function (DUF2172)
JV59_RS14485	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JV59_RS14495	COG0318	PFAM AMP-dependent synthetase and ligase
JV59_RS14505	COG2089	acid synthase
JV59_RS14515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JV59_RS14520	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JV59_RS14530	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JV59_RS14535	COG1086	Polysaccharide biosynthesis protein
JV59_RS14545	COG0438	transferase activity, transferring glycosyl groups
JV59_RS14580	COG1519	Transferase
JV59_RS14595	COG3642	lipopolysaccharide core region biosynthetic process
JV59_RS14600	COG0859	PFAM glycosyl transferase family 9
JV59_RS14605	COG0463	Glycosyl transferase, family 2
JV59_RS14615	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JV59_RS14635	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JV59_RS14640	COG2003	Belongs to the UPF0758 family
JV59_RS14645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JV59_RS14650	COG1309	transcriptional regulator
JV59_RS14655	COG1560	Kdo2-lipid A biosynthetic process
JV59_RS14660	COG1560	Kdo2-lipid A biosynthetic process
JV59_RS14665	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JV59_RS14670	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JV59_RS14675	COG1561	YicC-like family, N-terminal region
JV59_RS14695	COG3210	domain, Protein
JV59_RS14700	COG2831	hemolysin activation secretion protein
JV59_RS14705	COG2252	PERMEase
JV59_RS14715	COG0848	biopolymer transport protein
JV59_RS14745	COG1595	DNA-templated transcription, initiation
JV59_RS14750	COG0194	GDP metabolic process
JV59_RS14755	COG1758	RNA polymerase activity
JV59_RS14760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JV59_RS14765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JV59_RS14770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JV59_RS14775	COG1218	3'(2'),5'-bisphosphate nucleotidase
JV59_RS14780	COG0494	nUDIX hydrolase
JV59_RS14785	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JV59_RS14785	COG0316	Belongs to the HesB IscA family
JV59_RS14795	COG0596	Alpha beta hydrolase
JV59_RS14805	COG2183	response to ionizing radiation
JV59_RS14815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JV59_RS14835	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
JV59_RS14840	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
JV59_RS14845	COG3156	type II secretion system protein K
JV59_RS14850	COG4795	General secretion pathway protein
JV59_RS14855	COG2165	general secretion pathway protein
JV59_RS14860	COG2165	general secretion pathway protein
JV59_RS14865	COG2165	general secretion pathway protein
JV59_RS14870	COG1459	type II secretion system
JV59_RS14875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JV59_RS14885	COG3031	protein transport across the cell outer membrane
JV59_RS14890	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JV59_RS14900	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JV59_RS14910	COG0456	acetyltransferase
JV59_RS14915	COG1490	D-aminoacyl-tRNA deacylase activity
JV59_RS14920	COG1295	ribonuclease BN
JV59_RS14930	COG1217	gtp-binding protein TYPA
JV59_RS14935	COG0174	glutamine synthetase
JV59_RS14940	COG3852	Histidine kinase
JV59_RS14945	COG2204	response regulator
JV59_RS14950	COG5001	Diguanylate cyclase
JV59_RS14950	COG3300	MHYT domain
JV59_RS14955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JV59_RS14995	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JV59_RS15010	COG0408	coproporphyrinogen oxidase activity
JV59_RS15020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JV59_RS15025	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JV59_RS15030	COG0551	DNA topoisomerase type I activity
JV59_RS15035	COG2922	Belongs to the Smg family
JV59_RS15040	COG0758	DNA mediated transformation
JV59_RS15055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JV59_RS15055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JV59_RS15060	COG0569	domain protein
JV59_RS15065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JV59_RS15075	COG1272	protein, Hemolysin III
JV59_RS15080	COG4326	sporulation control protein
JV59_RS15090	COG3084	Protein conserved in bacteria
JV59_RS15100	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JV59_RS15105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JV59_RS15110	COG0204	Acyl-transferase
JV59_RS15120	COG0606	chelatase, subunit chli
JV59_RS15130	COG3978	acetolactate synthase activity
JV59_RS15135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JV59_RS15140	COG0129	dihydroxy-acid dehydratase activity
JV59_RS15150	COG0604	alcohol dehydrogenase
JV59_RS15165	COG0425	Belongs to the sulfur carrier protein TusA family
JV59_RS15175	COG2119	membrane
JV59_RS15180	COG0752	glycyl-tRNA synthetase alpha subunit
JV59_RS15185	COG0751	glycine-tRNA ligase activity
JV59_RS15190	COG3977	Valine--pyruvate aminotransferase
JV59_RS15195	COG0071	Belongs to the small heat shock protein (HSP20) family
JV59_RS15200	COG0187	DNA topoisomerase II activity
JV59_RS15205	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JV59_RS15210	COG0592	DNA-directed DNA polymerase activity
JV59_RS15230	COG1126	abc transporter atp-binding protein
JV59_RS15235	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JV59_RS15245	COG0706	membrane insertase activity
JV59_RS15250	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JV59_RS15255	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JV59_RS15260	COG0445	tRNA wobble uridine modification
JV59_RS15265	COG0357	Ribosomal RNA small subunit methyltransferase G
JV59_RS15270	COG1192	Involved in chromosome partitioning
JV59_RS15275	COG1475	DNA binding
JV59_RS15280	COG3312	ion transport
JV59_RS15300	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JV59_RS15305	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JV59_RS15310	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JV59_RS15315	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JV59_RS15320	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JV59_RS15330	COG0765	amino acid transport
JV59_RS15340	COG2814	Major facilitator Superfamily
JV59_RS15345	COG0583	DNA-binding transcription factor activity
JV59_RS15350	COG3706	GGDEF domain
JV59_RS15355	COG0183	Belongs to the thiolase family
JV59_RS15365	COG1739	Uncharacterized protein family UPF0029
JV59_RS15370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JV59_RS15425	COG2132	Multicopper oxidase
JV59_RS15440	COG0352	thiamine-phosphate diphosphorylase activity
JV59_RS15445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JV59_RS15465	COG0006	proline dipeptidase activity
JV59_RS15465	COG0006	proline dipeptidase activity
JV59_RS15485	COG1522	sequence-specific DNA binding
JV59_RS15490	COG5001	Diguanylate cyclase
JV59_RS15490	COG5002	protein histidine kinase activity
JV59_RS15495	COG0742	ribosomal rna small subunit methyltransferase
JV59_RS15510	COG0589	response to stress
JV59_RS15515	COG1528	Iron-storage protein
JV59_RS15525	COG2081	HI0933 family
JV59_RS15555	COG1639	'signal transduction protein
JV59_RS15565	COG1322	Protein conserved in bacteria
JV59_RS15570	COG2226	methyltransferase
JV59_RS15585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JV59_RS15590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JV59_RS15595	COG0805	protein transport
JV59_RS15600	COG0084	hydrolase, TatD family'
JV59_RS15615	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JV59_RS15615	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JV59_RS15645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JV59_RS15650	COG0583	DNA-binding transcription factor activity
JV59_RS15655	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JV59_RS15660	COG2960	long-chain fatty acid transporting porin activity
JV59_RS15665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_RS15670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_RS15675	COG1309	transcriptional regulator
JV59_RS15720	COG0747	negative chemotaxis
JV59_RS15725	COG0601	transmembrane transport
JV59_RS15730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JV59_RS15745	COG0745	RESPONSE REGULATOR receiver
JV59_RS15770	COG0477	Major facilitator Superfamily
JV59_RS15780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JV59_RS15785	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JV59_RS15805	COG3220	belongs to the UPF0276 family
JV59_RS15815	COG0210	DNA helicase
JV59_RS15830	COG0405	Gamma-glutamyltransferase
JV59_RS15835	COG1280	lysine exporter protein (LysE YggA)
JV59_RS15845	COG2962	Rard protein
JV59_RS15850	COG0514	ATP-dependent DNA helicase (RecQ)
JV59_RS15860	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JV59_RS15865	COG0248	Ppx GppA phosphatase
JV59_RS15875	COG3118	belongs to the thioredoxin family
JV59_RS15890	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JV59_RS15925	COG3071	HemY protein
JV59_RS15930	COG2959	enzyme of heme biosynthesis
JV59_RS15935	COG1587	Uroporphyrinogen-III synthase
JV59_RS15940	COG0181	hydroxymethylbilane synthase activity
JV59_RS15945	COG3072	Adenylate cyclase
JV59_RS15950	COG1965	Belongs to the frataxin family
JV59_RS15960	COG0019	diaminopimelate decarboxylase activity
JV59_RS15965	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JV59_RS15975	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JV59_RS15980	COG1011	Hydrolase
JV59_RS15985	COG2199	diguanylate cyclase activity
JV59_RS15985	COG2200	EAL domain
JV59_RS15985	COG3287	FIST C domain
JV59_RS15990	COG3148	PFAM DTW domain containing protein
JV59_RS16005	COG0561	phosphatase activity
JV59_RS16015	COG1280	lysine exporter protein (LysE YggA)
JV59_RS16020	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JV59_RS16025	COG0640	Transcriptional regulator
JV59_RS16030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JV59_RS16075	COG2095	MarC family integral membrane protein
JV59_RS16085	COG0742	ribosomal rna small subunit methyltransferase
JV59_RS16090	COG0552	protein localization to endoplasmic reticulum
JV59_RS16095	COG2884	Cell division ATP-binding protein ftsE
JV59_RS16100	COG2177	Part of the ABC transporter FtsEX involved in
JV59_RS16105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JV59_RS16110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JV59_RS16120	COG1580	Controls the rotational direction of flagella during chemotaxis
JV59_RS16125	COG3161	chorismate lyase activity
JV59_RS16130	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JV59_RS16135	COG2937	Belongs to the GPAT DAPAT family
JV59_RS16140	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JV59_RS16145	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JV59_RS16155	COG0534	Mate efflux family protein
JV59_RS16160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JV59_RS16180	COG4206	TonB-dependent receptor
JV59_RS16190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JV59_RS16225	COG0006	proline dipeptidase activity
JV59_RS16240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JV59_RS16245	COG0601	transmembrane transport
JV59_RS16260	COG2186	Transcriptional regulator
JV59_RS16270	COG3938	Belongs to the proline racemase family
JV59_RS16285	COG2423	ornithine cyclodeaminase activity
JV59_RS16290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JV59_RS16295	COG3842	ATPase activity
JV59_RS16300	COG1176	ABC-type spermidine putrescine transport system, permease component I
JV59_RS16315	COG1280	lysine exporter protein (LysE YggA)
JV59_RS16325	COG1846	Transcriptional regulator
JV59_RS16370	COG2988	succinylglutamate desuccinylase activity
JV59_RS16375	COG0523	cobalamin synthesis protein
JV59_RS16380	COG4451	ribulose bisphosphate carboxylase, small
JV59_RS16380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JV59_RS16385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JV59_RS16440	COG0583	DNA-binding transcription factor activity
JV59_RS16445	COG1280	lysine exporter protein (LysE YggA)
JV59_RS16485	COG1253	flavin adenine dinucleotide binding
JV59_RS16520	COG0583	DNA-binding transcription factor activity
JV59_RS16525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JV59_RS16530	COG1686	Belongs to the peptidase S11 family
JV59_RS16535	COG2814	Major facilitator Superfamily
JV59_RS16545	COG1741	Belongs to the pirin family
JV59_RS16560	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_RS16585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JV59_RS16595	COG3314	Sporulation integral membrane protein YlbJ
JV59_RS16605	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JV59_RS16625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JV59_RS16635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JV59_RS16640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JV59_RS16645	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JV59_RS16670	COG1612	heme a metabolic process
JV59_RS16675	COG0109	protoheme IX farnesyltransferase activity
JV59_RS16680	COG0765	amino acid transport
JV59_RS16685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JV59_RS16690	COG0765	amino acid transport
JV59_RS16695	COG1126	abc transporter atp-binding protein
JV59_RS16700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JV59_RS16710	COG0366	Alpha amylase catalytic
JV59_RS16720	COG4989	oxidoreductase activity
JV59_RS16725	COG3706	GGDEF domain
JV59_RS16725	COG5001	Diguanylate cyclase
JV59_RS16725	COG2203	Gaf domain
JV59_RS16725	COG4251	negative regulation of phosphorylation
JV59_RS16735	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JV59_RS16740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JV59_RS16745	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JV59_RS16750	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JV59_RS16755	COG0438	transferase activity, transferring glycosyl groups
JV59_RS16770	COG1045	serine acetyltransferase
JV59_RS16780	COG0297	glycogen (starch) synthase activity
JV59_RS16780	COG0438	transferase activity, transferring glycosyl groups
JV59_RS16790	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JV59_RS16865	COG5001	Diguanylate cyclase
JV59_RS16870	COG0583	DNA-binding transcription factor activity
JV59_RS16875	COG2814	Major facilitator Superfamily
JV59_RS16890	COG0697	spore germination
JV59_RS16900	COG0534	Mate efflux family protein
JV59_RS16910	COG2249	NAD(P)H dehydrogenase (quinone) activity
JV59_RS16915	COG0546	phosphoglycolate phosphatase activity
JV59_RS16930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JV59_RS16930	COG1017	nitric oxide dioxygenase activity
JV59_RS16945	COG1278	Cold shock
JV59_RS16950	COG3036	rescue of stalled ribosome
JV59_RS16965	COG1686	Belongs to the peptidase S11 family
JV59_RS16980	COG3530	Putative quorum-sensing-regulated virulence factor
JV59_RS17000	COG1012	belongs to the aldehyde dehydrogenase family
JV59_RS17015	COG1136	(ABC) transporter
JV59_RS17020	COG4591	ABC-type transport system involved in lipoprotein release permease component
JV59_RS17035	COG3275	phosphorelay sensor kinase activity
JV59_RS17040	COG3279	Response regulator of the LytR AlgR family
JV59_RS17070	COG0366	Alpha amylase catalytic
JV59_RS17090	COG0747	negative chemotaxis
JV59_RS17095	COG4608	Belongs to the ABC transporter superfamily
JV59_RS17100	COG0444	Belongs to the ABC transporter superfamily
JV59_RS17105	COG0534	Mate efflux family protein
JV59_RS17110	COG0641	radical SAM
JV59_RS17130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JV59_RS17160	COG2130	NADP-dependent
JV59_RS17180	COG0642	Histidine kinase
JV59_RS17190	COG3706	GGDEF domain
JV59_RS17200	COG5001	Diguanylate cyclase
JV59_RS17205	COG1396	sequence-specific DNA binding
JV59_RS17210	COG4948	Mandelate Racemase Muconate Lactonizing
JV59_RS17220	COG0583	DNA-binding transcription factor activity
JV59_RS17225	COG0443	Heat shock 70 kDa protein
JV59_RS17255	COG1280	lysine exporter protein (LysE YggA)
JV59_RS17270	COG4232	protein-disulfide reductase activity
JV59_RS17275	COG3118	belongs to the thioredoxin family
JV59_RS17315	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JV59_RS17335	COG0668	transmembrane transport
JV59_RS17345	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JV59_RS17350	COG3123	guanosine phosphorylase activity
JV59_RS17365	COG0583	DNA-binding transcription factor activity
JV59_RS17390	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JV59_RS17405	COG3265	gluconokinase activity
JV59_RS17410	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JV59_RS17415	COG1609	Transcriptional regulator
JV59_RS17435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JV59_RS17440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JV59_RS17445	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JV59_RS17450	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
JV59_RS17480	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JV59_RS17485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JV59_RS17505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JV59_RS17530	COG0004	ammonium transporteR
JV59_RS17545	COG3469	chitinase activity
JV59_RS17555	COG1869	D-ribose catabolic process
JV59_RS17560	COG1129	ABC transporter
JV59_RS17565	COG1172	Belongs to the binding-protein-dependent transport system permease family
JV59_RS17570	COG1879	ABC-type sugar transport system periplasmic component
JV59_RS17575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_RS17580	COG1609	Transcriptional regulator
JV59_RS17585	COG3437	response regulator, receiver
JV59_RS17585	COG0784	Response regulator, receiver
JV59_RS17590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JV59_RS17590	COG4191	Histidine kinase
JV59_RS17600	COG0513	Belongs to the DEAD box helicase family
JV59_RS17610	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
JV59_RS17620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JV59_RS17635	COG0739	heme binding
JV59_RS17645	COG2814	Major facilitator Superfamily
JV59_RS17650	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JV59_RS17655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JV59_RS17665	COG0848	biopolymer transport protein
JV59_RS17670	COG0811	peptide transport
JV59_RS17675	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JV59_RS17685	COG3721	Heme iron utilization protein
JV59_RS17690	COG0748	coenzyme F420 binding
JV59_RS17695	COG2096	Adenosyltransferase
JV59_RS17700	COG3842	ATPase activity
JV59_RS17710	COG1175	transmembrane transport
JV59_RS17715	COG3833	ABC-type maltose transport systems, permease component
JV59_RS17755	COG0784	Response regulator, receiver
JV59_RS17755	COG5002	protein histidine kinase activity
JV59_RS17755	COG2205	protein histidine kinase activity
JV59_RS17765	COG0861	Integral membrane protein TerC family
JV59_RS17775	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JV59_RS17780	COG1566	PFAM secretion protein HlyD family protein
JV59_RS17805	COG0745	RESPONSE REGULATOR receiver
JV59_RS17840	COG0531	amino acid
JV59_RS17860	COG0673	inositol 2-dehydrogenase activity
JV59_RS17865	COG1765	OsmC-like protein
JV59_RS17870	COG0110	maltose O-acetyltransferase activity
JV59_RS17890	COG2304	oxidoreductase activity
JV59_RS17895	COG2304	oxidoreductase activity
JV59_RS17910	COG0714	Associated with various cellular activities
JV59_RS17925	COG0583	DNA-binding transcription factor activity
JV59_RS17930	COG0667	Aldo Keto reductase
JV59_RS17945	COG2205	protein histidine kinase activity
JV59_RS17950	COG0745	RESPONSE REGULATOR receiver
JV59_RS17965	COG0745	RESPONSE REGULATOR receiver
JV59_RS17970	COG2205	protein histidine kinase activity
JV59_RS17975	COG4452	Inner membrane protein CreD
JV59_RS17985	COG0346	lactoylglutathione lyase activity
JV59_RS18005	COG2202	Pas domain
JV59_RS18005	COG2200	EAL domain
JV59_RS18005	COG2199	diguanylate cyclase activity
JV59_RS18010	COG0156	8-amino-7-oxononanoate synthase activity
JV59_RS18015	COG1063	alcohol dehydrogenase
JV59_RS18045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JV59_RS18055	COG2195	Cleaves the N-terminal amino acid of tripeptides
JV59_RS18070	COG0798	PFAM Bile acid sodium symporter
JV59_RS18080	COG0612	Peptidase, M16
JV59_RS18085	COG0784	Response regulator, receiver
JV59_RS18085	COG2205	protein histidine kinase activity
JV59_RS18090	COG2205	protein histidine kinase activity
JV59_RS18090	COG0784	Response regulator, receiver
JV59_RS18110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JV59_RS18115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JV59_RS18120	COG3186	Phenylalanine-4-hydroxylase
JV59_RS18170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JV59_RS18175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JV59_RS18220	COG1454	alcohol dehydrogenase
JV59_RS18225	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
JV59_RS18235	COG1011	Hydrolase
JV59_RS18265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JV59_RS18270	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JV59_RS18285	COG3842	ATPase activity
JV59_RS18310	COG3104	oligopeptide transport
JV59_RS18315	COG2866	Carboxypeptidase
JV59_RS18320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JV59_RS18325	COG0583	DNA-binding transcription factor activity
JV59_RS18330	COG1760	l-serine dehydratase
JV59_RS18355	COG3706	GGDEF domain
JV59_RS18360	COG0784	Response regulator, receiver
JV59_RS18360	COG0835	chemotaxis
JV59_RS18365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JV59_RS18385	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_RS18395	COG0494	nUDIX hydrolase
JV59_RS18400	COG0714	Associated with various cellular activities
JV59_RS18405	COG2425	protein containing a von Willebrand factor type A (vWA) domain
JV59_RS18410	COG2814	Major facilitator Superfamily
JV59_RS18435	COG3706	GGDEF domain
JV59_RS18440	COG1846	Transcriptional regulator
JV59_RS18445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JV59_RS18450	COG2176	DNA-directed DNA polymerase activity
JV59_RS18460	COG0789	Transcriptional regulator
JV59_RS18470	COG5001	Diguanylate cyclase
JV59_RS18470	COG3300	MHYT domain
JV59_RS18475	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JV59_RS18485	COG2204	response regulator
JV59_RS18500	COG0515	serine threonine protein kinase
JV59_RS18500	COG2815	serine threonine protein kinase
JV59_RS18525	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JV59_RS18545	COG0583	DNA-binding transcription factor activity
JV59_RS18570	COG1858	cytochrome C peroxidase
JV59_RS18605	COG1716	ATPase activity
JV59_RS18605	COG5001	Diguanylate cyclase
JV59_RS18625	COG2910	NAD(P)H-binding
JV59_RS18630	COG0583	DNA-binding transcription factor activity
JV59_RS18635	COG1115	amino acid carrier protein
JV59_RS18650	COG1741	Belongs to the pirin family
JV59_RS18655	COG2259	Doxx family
JV59_RS18685	COG1024	Enoyl-CoA hydratase
JV59_RS18690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JV59_RS18695	COG1960	acyl-CoA dehydrogenase activity
JV59_RS18705	COG0183	Belongs to the thiolase family
JV59_RS18715	COG1960	acyl-CoA dehydrogenase activity
JV59_RS18720	COG1024	Enoyl-CoA hydratase
JV59_RS18725	COG1024	Enoyl-CoA hydratase
JV59_RS18735	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_RS18740	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
JV59_RS18760	COG3706	GGDEF domain
JV59_RS18785	COG2203	Gaf domain
JV59_RS18785	COG2199	diguanylate cyclase activity
JV59_RS18840	COG0243	molybdopterin cofactor binding
JV59_RS18845	COG1648	precorrin-2 dehydrogenase activity
JV59_RS18845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JV59_RS18850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JV59_RS18860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JV59_RS18860	COG1116	anion transmembrane transporter activity
JV59_RS18865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JV59_RS18870	COG1116	anion transmembrane transporter activity
JV59_RS18875	COG2146	nitrite reductase [NAD(P)H] activity
JV59_RS18875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JV59_RS18880	COG2146	nitrite reductase [NAD(P)H] activity
JV59_RS18905	COG3118	belongs to the thioredoxin family
JV59_RS18910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JV59_RS18920	COG0419	ATPase involved in DNA repair
JV59_RS18925	COG0784	Response regulator, receiver
JV59_RS18925	COG2205	protein histidine kinase activity
JV59_RS18930	COG0156	8-amino-7-oxononanoate synthase activity
JV59_RS18940	COG0038	chloride channel
JV59_RS18945	COG0523	cobalamin synthesis protein
JV59_RS18950	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JV59_RS18960	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JV59_RS18995	COG1522	sequence-specific DNA binding
JV59_RS19000	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JV59_RS19005	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JV59_RS19030	COG2897	thiosulfate sulfurtransferase activity
JV59_RS19040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JV59_RS19055	COG0513	Belongs to the DEAD box helicase family
JV59_RS19065	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JV59_RS19065	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JV59_RS19070	COG0814	amino acid
JV59_RS19080	COG0513	Belongs to the DEAD box helicase family
JV59_RS19110	COG1214	PFAM Peptidase M22, glycoprotease
JV59_RS19110	COG0456	acetyltransferase
JV59_RS19125	COG0346	lactoylglutathione lyase activity
JV59_RS19135	COG3048	D-serine ammonia-lyase activity
JV59_RS19140	COG0583	DNA-binding transcription factor activity
JV59_RS19150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JV59_RS19155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_RS19170	COG0546	phosphoglycolate phosphatase activity
JV59_RS19180	COG0800	Aldolase
JV59_RS19185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_RS19190	COG1263	PTS System
JV59_RS19190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JV59_RS19200	COG2188	Transcriptional regulator
JV59_RS19205	COG1803	Methylglyoxal synthase
JV59_RS19210	COG1879	ABC-type sugar transport system periplasmic component
JV59_RS19215	COG0784	Response regulator, receiver
JV59_RS19215	COG2198	Histidine kinase
JV59_RS19215	COG2205	protein histidine kinase activity
JV59_RS19230	COG1979	alcohol dehydrogenase
JV59_RS19235	COG2207	Transcriptional regulator
JV59_RS19240	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JV59_RS19250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_RS19250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_RS19250	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JV59_RS19255	COG1105	Belongs to the carbohydrate kinase PfkB family
JV59_RS19260	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_RS19260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_RS19270	COG1609	Transcriptional regulator
JV59_RS19290	COG0725	ABC transporter, periplasmic molybdate-binding protein
JV59_RS19295	COG4149	molybdate abc transporter
JV59_RS19300	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JV59_RS19310	COG3706	GGDEF domain
JV59_RS19310	COG2203	Gaf domain
JV59_RS19310	COG4251	negative regulation of phosphorylation
JV59_RS19310	COG5001	Diguanylate cyclase
JV59_RS19315	COG3706	GGDEF domain
JV59_RS19330	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JV59_RS19335	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JV59_RS19345	COG0745	RESPONSE REGULATOR receiver
JV59_RS19370	COG0023	Translation Initiation Factor
JV59_RS19385	COG1181	Belongs to the D-alanine--D-alanine ligase family
JV59_RS19390	COG3266	domain, Protein
JV59_RS19395	COG0045	succinate-CoA ligase (ADP-forming) activity
JV59_RS19395	COG1042	CoA-binding domain protein
JV59_RS19395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JV59_RS19400	COG0583	DNA-binding transcription factor activity
JV59_RS19405	COG4771	TonB-dependent receptor
JV59_RS19405	COG1629	transport
JV59_RS19415	COG4533	DNA binding
JV59_RS19425	COG2050	protein possibly involved in aromatic compounds catabolism
JV59_RS19445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JV59_RS19455	COG0840	transmembrane signaling receptor activity
JV59_RS19460	COG0784	Response regulator, receiver
JV59_RS19460	COG2205	protein histidine kinase activity
JV59_RS19465	COG0745	RESPONSE REGULATOR receiver
JV59_RS19480	COG1605	Chorismate mutase
JV59_RS19510	COG0737	Belongs to the 5'-nucleotidase family
JV59_RS19515	COG3593	DNA synthesis involved in DNA repair
JV59_RS19525	COG0583	DNA-binding transcription factor activity
JV59_RS19530	COG2116	formate transmembrane transporter activity
JV59_RS19535	COG2353	YceI-like domain
JV59_RS19540	COG3038	cytochrome b561
JV59_RS19560	COG3069	C4-dicarboxylate transmembrane transporter activity
JV59_RS19565	COG2197	response regulator
JV59_RS19570	COG3850	Histidine kinase
JV59_RS19575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JV59_RS19585	COG0243	molybdopterin cofactor binding
JV59_RS19600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JV59_RS19605	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JV59_RS19615	COG1984	allophanate hydrolase subunit 2
JV59_RS19620	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JV59_RS19625	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JV59_RS19630	COG4181	ATPase activity
JV59_RS19640	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JV59_RS19645	COG3300	MHYT domain
JV59_RS19645	COG5001	Diguanylate cyclase
JV59_RS19655	COG0484	heat shock protein binding
JV59_RS19675	COG0210	DNA helicase
JV59_RS19680	COG1289	transmembrane transporter activity
JV59_RS19705	COG0784	Response regulator, receiver
JV59_RS19705	COG5002	protein histidine kinase activity
JV59_RS19720	COG2827	Endonuclease containing a URI domain
JV59_RS19725	COG3132	Protein of unknown function, DUF480
JV59_RS19735	COG2926	Belongs to the UPF0265 family
JV59_RS19745	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JV59_RS19750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JV59_RS19755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JV59_RS19760	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
JV59_RS19765	COG0247	lactate metabolic process
JV59_RS19785	COG0545	Peptidyl-prolyl cis-trans isomerase
JV59_RS19795	COG4067	protein conserved in archaea
JV59_RS19795	COG0189	ligase activity
JV59_RS19805	COG0602	queuosine metabolic process
JV59_RS19810	COG1328	CTP reductase activity
JV59_RS19865	COG2814	Major facilitator Superfamily
JV59_RS19870	COG1794	racemase activity, acting on amino acids and derivatives
JV59_RS19885	COG0183	Belongs to the thiolase family
JV59_RS19900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_RS19905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_RS19910	COG1309	transcriptional regulator
JV59_RS19915	COG1609	Transcriptional regulator
JV59_RS19925	COG3250	beta-galactosidase activity
JV59_RS19965	COG1522	sequence-specific DNA binding
JV59_RS20000	COG2815	serine threonine protein kinase
JV59_RS20000	COG0515	serine threonine protein kinase
JV59_RS20025	COG3501	Rhs element vgr protein
JV59_RS20060	COG0739	heme binding
JV59_RS20070	COG2199	diguanylate cyclase activity
JV59_RS20070	COG2203	Gaf domain
JV59_RS20075	COG0840	transmembrane signaling receptor activity
JV59_RS20085	COG2271	Major facilitator Superfamily
JV59_RS20105	COG4206	TonB-dependent receptor
JV59_RS20115	COG0004	ammonium transporteR
JV59_RS20130	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JV59_RS20135	COG4604	ABC transporter, ATP-binding protein
JV59_RS20140	COG4605	iron ion homeostasis
JV59_RS20145	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JV59_RS20195	COG4172	Belongs to the ABC transporter superfamily
JV59_RS20200	COG4239	(ABC) transporter, permease
JV59_RS20205	COG4174	ABC transporter (Permease)
JV59_RS20210	COG4166	transmembrane transport
JV59_RS20225	COG0840	transmembrane signaling receptor activity
JV59_RS20230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JV59_RS20235	COG1067	ATP-dependent peptidase activity
JV59_RS20245	COG4172	Belongs to the ABC transporter superfamily
JV59_RS20250	COG0583	DNA-binding transcription factor activity
JV59_RS20255	COG1620	l-lactate permease
JV59_RS20260	COG1304	FMN binding
JV59_RS20280	COG4175	Glycine betaine
JV59_RS20280	COG3448	diguanylate cyclase activity
JV59_RS20305	COG1309	transcriptional regulator
JV59_RS20325	COG1346	cytolysis
JV59_RS20335	COG0516	GMP reductase activity
JV59_RS20340	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JV59_RS20340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JV59_RS20355	COG3437	response regulator, receiver
JV59_RS20360	COG2205	protein histidine kinase activity
JV59_RS20360	COG3850	Histidine kinase
JV59_RS20360	COG3437	response regulator, receiver
JV59_RS20360	COG4999	Histidine kinase
JV59_RS20370	COG2172	sigma factor antagonist activity
JV59_RS20380	COG1366	Belongs to the anti-sigma-factor antagonist family
JV59_RS20385	COG0840	transmembrane signaling receptor activity
JV59_RS20420	COG0366	Alpha amylase catalytic
JV59_RS20430	COG2354	Protein conserved in bacteria
JV59_RS20450	COG2199	diguanylate cyclase activity
JV59_RS20455	COG1349	DNA-binding transcription factor activity
JV59_RS20465	COG0633	Ferredoxin
JV59_RS20465	COG0633	Ferredoxin
JV59_RS20465	COG3217	Mosc domain protein beta barrel domain protein
JV59_RS20465	COG3217	Mosc domain protein beta barrel domain protein
JV59_RS20470	COG0418	dihydroorotase activity
JV59_RS20490	COG2197	response regulator
JV59_RS20495	COG3851	Histidine kinase
JV59_RS20500	COG2271	Major facilitator Superfamily
JV59_RS20520	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JV59_RS20525	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JV59_RS20530	COG0363	glucosamine-6-phosphate deaminase activity
JV59_RS20535	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JV59_RS20555	COG3284	Transcriptional regulator
JV59_RS20560	COG1012	belongs to the aldehyde dehydrogenase family
JV59_RS20590	COG0579	oxidoreductase
JV59_RS20595	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JV59_RS20600	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JV59_RS20610	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JV59_RS20615	COG0840	transmembrane signaling receptor activity
JV59_RS20640	COG2814	Major facilitator Superfamily
JV59_RS20645	COG0583	DNA-binding transcription factor activity
JV59_RS20675	COG0564	pseudouridine synthase activity
JV59_RS20705	COG0251	oxidation-reduction process
JV59_RS20740	COG0110	maltose O-acetyltransferase activity
JV59_RS20750	COG1621	beta-fructofuranosidase activity
JV59_RS20760	COG3842	ATPase activity
JV59_RS20765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JV59_RS20770	COG1554	hydrolase, family 65, central catalytic
JV59_RS20775	COG0395	ABC-type sugar transport system, permease component
JV59_RS20780	COG1175	transmembrane transport
JV59_RS20795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JV59_RS20805	COG0573	inorganic phosphate transmembrane transporter activity
JV59_RS20845	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JV59_RS20850	COG3447	MASE1 domain protein
JV59_RS20850	COG5001	Diguanylate cyclase
JV59_RS20850	COG5002	protein histidine kinase activity
JV59_RS20860	COG0513	Belongs to the DEAD box helicase family
JV59_RS20865	COG3097	Belongs to the UPF0267 family
JV59_RS20880	COG3706	GGDEF domain
JV59_RS20885	COG1309	transcriptional regulator
JV59_RS20890	COG2130	NADP-dependent
JV59_RS20905	COG2084	Dehydrogenase
JV59_RS20925	COG0366	Alpha amylase catalytic
JV59_RS20935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JV59_RS20940	COG0625	glutathione transferase activity
JV59_RS20945	COG0346	lactoylglutathione lyase activity
JV59_RS20950	COG1054	Belongs to the UPF0176 family
JV59_RS20995	COG1131	(ABC) transporter
JV59_RS21000	COG0842	Transport permease protein
JV59_RS21035	COG5002	protein histidine kinase activity
JV59_RS21040	COG0745	RESPONSE REGULATOR receiver
JV59_RS21060	COG1309	transcriptional regulator
JV59_RS21070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_RS21075	COG2813	Specifically methylates the guanine in position
JV59_RS21095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JV59_RS21115	COG1805	sodium ion transport
JV59_RS21120	COG1271	oxidase subunit
JV59_RS21125	COG1294	oxidase, subunit
JV59_RS21140	COG0719	Fe-S assembly protein
JV59_RS21145	COG0396	ATPase activity
JV59_RS21150	COG0719	Fe-S assembly protein
JV59_RS21155	COG0316	Belongs to the HesB IscA family
JV59_RS21165	COG1780	Probably involved in ribonucleotide reductase function
JV59_RS21170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JV59_RS21180	COG1357	PFAM Pentapeptide repeats (8 copies)
JV59_RS21185	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JV59_RS21185	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JV59_RS21205	COG1522	sequence-specific DNA binding
JV59_RS21215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JV59_RS21235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JV59_RS21240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JV59_RS21240	COG2207	Transcriptional regulator
JV59_RS21250	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JV59_RS21250	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JV59_RS21275	COG0697	spore germination
JV59_RS21295	COG0415	Belongs to the DNA photolyase family
JV59_RS21335	COG0840	transmembrane signaling receptor activity
JV59_RS21360	COG0583	DNA-binding transcription factor activity
JV59_RS21375	COG0840	transmembrane signaling receptor activity
JV59_RS21385	COG4580	involved in the transport of maltose and maltodextrins
JV59_RS21400	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JV59_RS21415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JV59_RS21420	COG0509	glycine decarboxylation via glycine cleavage system
JV59_RS21440	COG0583	DNA-binding transcription factor activity
JV59_RS21450	COG1132	(ABC) transporter
JV59_RS21455	COG0589	response to stress
JV59_RS21465	COG2111	Na H antiporter
JV59_RS21465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JV59_RS21470	COG1006	Multisubunit Na H antiporter MnhC subunit
JV59_RS21475	COG0651	ATP synthesis coupled electron transport
JV59_RS21480	COG1863	multisubunit Na H antiporter MnhE subunit
JV59_RS21485	COG2212	antiporter activity
JV59_RS21490	COG1320	monovalent cation:proton antiporter activity
JV59_RS21495	COG4191	Histidine kinase
JV59_RS21495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JV59_RS21535	COG0488	(ABC) transporter
JV59_RS21540	COG0673	inositol 2-dehydrogenase activity
JV59_RS21555	COG5553	Cysteine dioxygenase type I
JV59_RS21560	COG0300	oxidoreductase activity
JV59_RS21585	COG3047	cAMP biosynthetic process
JV59_RS21590	COG0739	heme binding
JV59_RS21615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JV59_RS21620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JV59_RS21630	COG3383	formate dehydrogenase (NAD+) activity
JV59_RS21670	COG1234	tRNA 3'-trailer cleavage
JV59_RS21675	COG0583	DNA-binding transcription factor activity
JV59_RS21685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JV59_RS21695	COG3304	Inner membrane component domain
JV59_RS21700	COG2329	Antibiotic biosynthesis monooxygenase
JV59_RS21710	COG3046	protein related to deoxyribodipyrimidine photolyase
JV59_RS21715	COG0415	Belongs to the DNA photolyase family
JV59_RS21740	COG3604	Transcriptional regulator
JV59_RS21745	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JV59_RS21760	COG0583	DNA-binding transcription factor activity
JV59_RS21770	COG1151	hydroxylamine reductase activity
JV59_RS21775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JV59_RS21780	COG0583	DNA-binding transcription factor activity
JV59_RS21790	COG3314	Sporulation integral membrane protein YlbJ
JV59_RS21800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JV59_RS21825	COG0745	RESPONSE REGULATOR receiver
JV59_RS21830	COG3850	Histidine kinase
JV59_RS21830	COG5002	protein histidine kinase activity
JV59_RS21840	COG1288	antiporter activity
JV59_RS21845	COG3608	succinylglutamate desuccinylase aspartoacylase
JV59_RS21875	COG1522	sequence-specific DNA binding
JV59_RS21885	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JV59_RS21890	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JV59_RS21895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JV59_RS21950	COG0363	glucosamine-6-phosphate deaminase activity
JV59_RS21955	COG4720	Psort location CytoplasmicMembrane, score
JV59_RS21960	COG1122	ATPase activity
JV59_RS21980	COG1162	GTPase activity
JV59_RS21985	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JV59_RS22000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JV59_RS22005	COG0581	inorganic phosphate transmembrane transporter activity
JV59_RS22010	COG0573	inorganic phosphate transmembrane transporter activity
JV59_RS22020	COG0840	transmembrane signaling receptor activity
JV59_RS22025	COG4221	oxidoreductase activity
JV59_RS22045	COG1477	protein flavinylation
JV59_RS22110	COG4964	Belongs to the GSP D family
JV59_RS22135	COG0583	DNA-binding transcription factor activity
JV59_RS22145	COG0534	Mate efflux family protein
JV59_RS22155	COG2095	MarC family integral membrane protein
JV59_RS22175	COG4176	ABC-type proline glycine betaine transport system permease component
JV59_RS22180	COG4175	Glycine betaine
JV59_RS22180	COG3448	diguanylate cyclase activity
JV59_RS22235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JV59_RS22260	COG4264	IucA IucC family
JV59_RS22275	COG1120	ATPase activity
JV59_RS22280	COG2814	Major facilitator Superfamily
JV59_RS22290	COG4968	Prepilin-type N-terminal cleavage methylation domain
JV59_RS22295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_RS22295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_RS22295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_RS22305	COG0383	alpha-mannosidase activity
JV59_RS22310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_RS22335	COG1414	Transcriptional regulator
JV59_RS22350	COG0667	Aldo Keto reductase
JV59_RS22370	COG0583	DNA-binding transcription factor activity
JV59_RS22400	COG1733	regulation of RNA biosynthetic process
JV59_RS22440	COG1733	regulation of RNA biosynthetic process
JV59_RS22460	COG4977	sequence-specific DNA binding
JV59_RS22460	COG1917	Cupin 2, conserved barrel domain protein
JV59_RS22465	COG4771	TonB-dependent receptor
JV59_RS22470	COG2814	Major facilitator Superfamily
JV59_RS22500	COG1169	isochorismate synthase
JV59_RS22505	COG1021	2,3-dihydroxybenzoate-AMP ligase
JV59_RS22510	COG1132	(ABC) transporter
JV59_RS22515	COG1132	(ABC) transporter
JV59_RS22550	COG0561	phosphatase activity
JV59_RS22555	COG1482	cell wall glycoprotein biosynthetic process
JV59_RS22560	COG0383	alpha-mannosidase activity
JV59_RS22565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JV59_RS22565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_RS22565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JV59_RS22570	COG2188	Transcriptional regulator
JV59_RS22620	COG0300	oxidoreductase activity
JV59_RS22630	COG0583	DNA-binding transcription factor activity
JV59_RS22640	COG2249	NAD(P)H dehydrogenase (quinone) activity
JV59_RS22690	COG1619	proteins homologs of microcin C7 resistance protein MccF
JV59_RS22705	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JV59_RS22710	COG1640	4-alpha-glucanotransferase
JV59_RS22715	COG0058	SHG alpha-glucan phosphorylase activity
JV59_RS22720	COG2909	trisaccharide binding
JV59_RS22730	COG0456	acetyltransferase
JV59_RS22765	COG2207	Transcriptional regulator
JV59_RS22770	COG1335	isochorismatase
JV59_RS22775	COG1404	Belongs to the peptidase S8 family
JV59_RS22780	COG0402	S-adenosylhomocysteine deaminase activity
JV59_RS22810	COG3795	YCII-related domain
JV59_RS22835	COG2186	Transcriptional regulator
JV59_RS22845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JV59_RS22855	COG0402	S-adenosylhomocysteine deaminase activity
JV59_RS22865	COG5002	protein histidine kinase activity
JV59_RS22865	COG0784	Response regulator, receiver
JV59_RS22865	COG2205	protein histidine kinase activity
JV59_RS22875	COG1522	sequence-specific DNA binding
JV59_RS22885	COG0840	transmembrane signaling receptor activity
JV59_RS22900	COG4266	Belongs to the allantoicase family
JV59_RS22920	COG2252	PERMEase
JV59_RS22935	COG0596	Alpha beta hydrolase
JV59_RS22940	COG3214	Protein conserved in bacteria
JV59_RS22955	COG2205	protein histidine kinase activity
JV59_RS22970	COG0583	DNA-binding transcription factor activity
JV59_RS22995	COG3179	chitinase
JV59_RS23020	COG0109	protoheme IX farnesyltransferase activity
JV59_RS23025	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JV59_RS23030	COG1845	cytochrome c oxidase, subunit III
JV59_RS23035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JV59_RS23040	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JV59_RS23050	COG2706	6-phosphogluconolactonase activity
JV59_RS23060	COG0800	Aldolase
JV59_RS23065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JV59_RS23095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JV59_RS23100	COG0840	transmembrane signaling receptor activity
JV59_RS23135	COG0830	nickel cation binding
JV59_RS23145	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JV59_RS23150	COG0804	urea catabolic process
JV59_RS23155	COG0832	Belongs to the urease beta subunit family
JV59_RS23160	COG0831	urea catabolic process
JV59_RS23185	COG0559	Belongs to the binding-protein-dependent transport system permease family
JV59_RS23200	COG1917	Cupin 2, conserved barrel domain protein
JV59_RS23200	COG2207	Transcriptional regulator
JV59_RS23230	COG2084	Dehydrogenase
JV59_RS23235	COG3622	Belongs to the hyi family
JV59_RS23240	COG3960	tartronate-semialdehyde synthase activity
JV59_RS23245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JV59_RS23260	COG1288	antiporter activity
JV59_RS23290	COG1846	Transcriptional regulator
JV59_RS23295	COG0697	spore germination
JV59_RS23300	COG3300	MHYT domain
JV59_RS23300	COG5001	Diguanylate cyclase
JV59_RS23315	COG1051	belongs to the nudix hydrolase family
JV59_RS23320	COG0583	DNA-binding transcription factor activity
JV59_RS23340	COG1733	regulation of RNA biosynthetic process
JV59_RS23345	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_RS23355	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_RS23390	COG0444	Belongs to the ABC transporter superfamily
JV59_RS23395	COG4608	Belongs to the ABC transporter superfamily
JV59_RS23425	COG1444	tRNA N-acetyltransferase activity
JV59_RS23430	COG0840	transmembrane signaling receptor activity
JV59_RS23455	COG0835	chemotaxis
JV59_RS23460	COG0840	transmembrane signaling receptor activity
JV59_RS23465	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JV59_RS23510	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JV59_RS23535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JV59_RS23570	COG0583	DNA-binding transcription factor activity
JV59_RS23595	COG0546	phosphoglycolate phosphatase activity
JV59_RS23600	COG3842	ATPase activity
JV59_RS23605	COG0589	response to stress
JV59_RS23615	COG2723	6-phospho-beta-galactosidase activity
JV59_RS23620	COG0768	penicillin binding
JV59_RS23625	COG0840	transmembrane signaling receptor activity
JV59_RS23645	COG0583	DNA-binding transcription factor activity
JV59_RS23660	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_RS23660	COG3321	synthase
JV59_RS23660	COG0604	alcohol dehydrogenase
JV59_RS23665	COG0656	L-ascorbic acid biosynthetic process
JV59_RS23670	COG0351	phosphomethylpyrimidine kinase
JV59_RS23675	COG1116	anion transmembrane transporter activity
JV59_RS23680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JV59_RS23685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JV59_RS23690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JV59_RS23710	COG3708	Transcriptional regulator
JV59_RS23710	COG2207	Transcriptional regulator
JV59_RS23720	COG0671	phosphoesterase, PA-phosphatase related
JV59_RS23730	COG0438	transferase activity, transferring glycosyl groups
JV59_RS23740	COG1940	carbohydrate kinase activity
JV59_RS23755	COG1175	transmembrane transport
JV59_RS23765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JV59_RS23805	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_RS23805	COG0604	alcohol dehydrogenase
JV59_RS23805	COG3321	synthase
JV59_RS23815	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JV59_RS23815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JV59_RS23825	COG0251	oxidation-reduction process
JV59_RS23830	COG0697	spore germination
JV59_RS23845	COG1595	DNA-templated transcription, initiation
JV59_RS23855	COG3314	Sporulation integral membrane protein YlbJ
JV59_RS23885	COG0471	metal ion transport
JV59_RS23890	COG4191	Histidine kinase
JV59_RS23890	COG2205	protein histidine kinase activity
JV59_RS23890	COG0745	RESPONSE REGULATOR receiver
JV59_RS23895	COG0745	RESPONSE REGULATOR receiver
JV59_RS23920	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JV59_RS23930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JV59_RS23935	COG0745	RESPONSE REGULATOR receiver
JV59_RS23940	COG2205	protein histidine kinase activity
JV59_RS23940	COG3437	response regulator, receiver
JV59_RS23940	COG3850	Histidine kinase
JV59_RS23940	COG4999	Histidine kinase
JV59_RS23960	COG0745	RESPONSE REGULATOR receiver
JV59_RS23970	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JV59_RS23985	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JV59_RS23990	COG3366	ferrous iron transmembrane transporter activity
JV59_RS23995	COG0700	Nucleoside recognition
JV59_RS24005	COG2207	Transcriptional regulator
JV59_RS24015	COG1404	Belongs to the peptidase S8 family
JV59_RS24020	COG2200	EAL domain
JV59_RS24195	COG0583	DNA-binding transcription factor activity
JV59_RS24200	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_RS24215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JV59_RS24225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JV59_RS24230	COG0584	glycerophosphoryl diester phosphodiesterase
JV59_RS24255	COG0583	DNA-binding transcription factor activity
JV59_RS24260	COG0393	Putative heavy-metal-binding
JV59_RS24265	COG1671	Belongs to the UPF0178 family
JV59_RS24280	COG1999	signal sequence binding
JV59_RS24290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JV59_RS24295	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JV59_RS24300	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JV59_RS24305	COG3033	Beta-eliminating lyase
JV59_RS24335	COG0259	pyridoxamine-phosphate oxidase activity
JV59_RS24345	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JV59_RS24390	COG1132	(ABC) transporter
JV59_RS24400	COG0583	DNA-binding transcription factor activity
JV59_RS24415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JV59_RS24425	COG0786	glutamate:sodium symporter activity
JV59_RS24430	COG1566	PFAM secretion protein HlyD family protein
JV59_RS24460	COG0813	purine-nucleoside phosphorylase activity
JV59_RS24465	COG3272	Protein of unknown function (DUF1722)
JV59_RS24470	COG0789	Transcriptional regulator
JV59_RS24475	COG0415	Belongs to the DNA photolyase family
JV59_RS24480	COG1376	ErfK ybiS ycfS ynhG family protein
JV59_RS24480	COG1388	LysM domain
JV59_RS24490	COG0513	Belongs to the DEAD box helicase family
JV59_RS24495	COG3291	Pkd domain containing protein
JV59_RS24500	COG3568	Endonuclease Exonuclease Phosphatase
JV59_RS24535	COG0604	alcohol dehydrogenase
JV59_RS24545	COG0702	epimerase
JV59_RS24565	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
JV59_RS24580	COG0583	DNA-binding transcription factor activity
JV59_RS24585	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_RS24690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JV59_RS24700	COG2084	Dehydrogenase
JV59_RS24785	COG0494	nUDIX hydrolase
JV59_RS24835	COG1742	UPF0060 membrane protein
JV59_RS24845	COG0251	oxidation-reduction process
JV59_RS24875	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JV59_RS24960	COG1074	ATP-dependent DNA helicase activity
JV59_RS24975	COG1335	isochorismatase
JV59_RS24980	COG1741	Belongs to the pirin family
JV59_RS24985	COG0583	DNA-binding transcription factor activity
JV59_RS25015	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_RS25025	COG2274	protein secretion by the type I secretion system
JV59_RS25035	COG2274	protein secretion by the type I secretion system
JV59_RS25045	COG0583	DNA-binding transcription factor activity
JV59_RS25080	COG3706	GGDEF domain
JV59_RS25090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JV59_RS25095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JV59_RS25130	COG0693	protein deglycase activity
JV59_RS25195	COG1335	isochorismatase
JV59_RS25200	COG2169	Transcriptional regulator
JV59_RS25245	COG2267	carboxylic ester hydrolase activity
JV59_RS25270	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JV59_RS25275	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JV59_RS25290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JV59_RS25320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JV59_RS25370	COG2003	Belongs to the UPF0758 family
JV59_RS25485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JV59_RS25515	COG0215	cysteine-tRNA ligase activity
JV59_RS25525	COG1045	serine acetyltransferase
JV59_RS25530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JV59_RS25575	COG2814	Major facilitator Superfamily
JV59_RS25620	COG1401	restriction endodeoxyribonuclease activity
JV59_RS25675	COG2026	Addiction module toxin, RelE StbE family
JV59_RS25720	COG1609	Transcriptional regulator
JV59_RS25730	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JV59_RS25740	COG1280	lysine exporter protein (LysE YggA)
JV59_RS25745	COG0735	belongs to the Fur family
JV59_RS25850	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JV59_RS25850	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JV59_RS25855	COG0840	transmembrane signaling receptor activity
JV59_RS25860	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JV59_RS25880	COG1181	Belongs to the D-alanine--D-alanine ligase family
JV59_RS25885	COG4191	Histidine kinase
JV59_RS25950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JV59_RS25970	COG1192	Involved in chromosome partitioning
JV59_RS25980	COG2814	Major facilitator Superfamily
JV59_RS26040	COG4191	Histidine kinase
JV59_RS26045	COG5001	Diguanylate cyclase
JV59_RS26045	COG3300	MHYT domain
JV59_RS26110	COG0814	amino acid
JV59_RS26130	COG1028	Short-chain dehydrogenase reductase Sdr
JV59_RS26135	COG0583	DNA-binding transcription factor activity
JV59_RS26145	COG3527	Alpha-acetolactate decarboxylase
JV59_RS26155	COG0745	RESPONSE REGULATOR receiver
JV59_RS26160	COG2205	protein histidine kinase activity
JV59_RS26285	COG1309	transcriptional regulator
JV59_RS26390	COG5002	protein histidine kinase activity
JV59_RS26400	COG2200	EAL domain
JV59_RS26410	COG2203	Gaf domain
JV59_RS26410	COG3706	GGDEF domain
JV59_RS26410	COG4251	negative regulation of phosphorylation
JV59_RS26410	COG5001	Diguanylate cyclase
JV59_RS26430	COG2977	Belongs to the P-Pant transferase superfamily