locus-tag	class	description
IX92_RS00005	COG0445	tRNA wobble uridine modification
IX92_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
IX92_RS00015	COG1192	Involved in chromosome partitioning
IX92_RS00020	COG1475	DNA binding
IX92_RS00025	COG3312	ion transport
IX92_RS00045	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IX92_RS00050	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IX92_RS00055	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IX92_RS00060	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IX92_RS00065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IX92_RS00075	COG0765	amino acid transport
IX92_RS00085	COG2814	Major facilitator Superfamily
IX92_RS00090	COG0583	DNA-binding transcription factor activity
IX92_RS00095	COG3706	GGDEF domain
IX92_RS00100	COG0183	Belongs to the thiolase family
IX92_RS00110	COG1739	Uncharacterized protein family UPF0029
IX92_RS00115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IX92_RS00170	COG2132	Multicopper oxidase
IX92_RS00190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IX92_RS00200	COG2022	thiamine diphosphate biosynthetic process
IX92_RS00210	COG0006	proline dipeptidase activity
IX92_RS00230	COG1522	sequence-specific DNA binding
IX92_RS00235	COG5001	Diguanylate cyclase
IX92_RS00235	COG5002	protein histidine kinase activity
IX92_RS00240	COG0742	ribosomal rna small subunit methyltransferase
IX92_RS00255	COG0589	response to stress
IX92_RS00260	COG1528	Iron-storage protein
IX92_RS00270	COG2081	HI0933 family
IX92_RS00300	COG1639	'signal transduction protein
IX92_RS00310	COG1322	Protein conserved in bacteria
IX92_RS00315	COG2226	methyltransferase
IX92_RS00330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IX92_RS00335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IX92_RS00340	COG0805	protein transport
IX92_RS00345	COG0084	hydrolase, TatD family'
IX92_RS00360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IX92_RS00360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IX92_RS00390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IX92_RS00395	COG0583	DNA-binding transcription factor activity
IX92_RS00400	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IX92_RS00405	COG2960	long-chain fatty acid transporting porin activity
IX92_RS00410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX92_RS00415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_RS00420	COG1309	transcriptional regulator
IX92_RS00465	COG0747	negative chemotaxis
IX92_RS00470	COG0601	transmembrane transport
IX92_RS00475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IX92_RS00490	COG0745	RESPONSE REGULATOR receiver
IX92_RS00510	COG0477	Major facilitator Superfamily
IX92_RS00520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IX92_RS00525	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IX92_RS00545	COG3220	belongs to the UPF0276 family
IX92_RS00555	COG0210	DNA helicase
IX92_RS00570	COG0405	Gamma-glutamyltransferase
IX92_RS00575	COG1280	lysine exporter protein (LysE YggA)
IX92_RS00585	COG2962	Rard protein
IX92_RS00590	COG0514	ATP-dependent DNA helicase (RecQ)
IX92_RS00600	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IX92_RS00605	COG0248	Ppx GppA phosphatase
IX92_RS00615	COG3118	belongs to the thioredoxin family
IX92_RS00630	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IX92_RS00690	COG3071	HemY protein
IX92_RS00695	COG2959	enzyme of heme biosynthesis
IX92_RS00700	COG1587	Uroporphyrinogen-III synthase
IX92_RS00705	COG0181	hydroxymethylbilane synthase activity
IX92_RS00710	COG3072	Adenylate cyclase
IX92_RS00715	COG1965	Belongs to the frataxin family
IX92_RS00725	COG0019	diaminopimelate decarboxylase activity
IX92_RS00730	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IX92_RS00740	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IX92_RS00745	COG1011	Hydrolase
IX92_RS00750	COG3287	FIST C domain
IX92_RS00750	COG2200	EAL domain
IX92_RS00750	COG2199	diguanylate cyclase activity
IX92_RS00755	COG3148	PFAM DTW domain containing protein
IX92_RS00770	COG0561	phosphatase activity
IX92_RS00780	COG1280	lysine exporter protein (LysE YggA)
IX92_RS00785	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IX92_RS00790	COG0640	Transcriptional regulator
IX92_RS00795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IX92_RS00840	COG2095	MarC family integral membrane protein
IX92_RS00850	COG0742	ribosomal rna small subunit methyltransferase
IX92_RS00855	COG0552	protein localization to endoplasmic reticulum
IX92_RS00860	COG2884	Cell division ATP-binding protein ftsE
IX92_RS00865	COG2177	Part of the ABC transporter FtsEX involved in
IX92_RS00870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IX92_RS00875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IX92_RS00885	COG1580	Controls the rotational direction of flagella during chemotaxis
IX92_RS00890	COG3161	chorismate lyase activity
IX92_RS00895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IX92_RS00900	COG2937	Belongs to the GPAT DAPAT family
IX92_RS00905	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IX92_RS00910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IX92_RS00920	COG0534	Mate efflux family protein
IX92_RS00925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IX92_RS00945	COG4206	TonB-dependent receptor
IX92_RS00955	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IX92_RS01020	COG0646	methionine synthase
IX92_RS01020	COG1410	methionine synthase
IX92_RS01025	COG2239	Acts as a magnesium transporter
IX92_RS01030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX92_RS01035	COG1660	Displays ATPase and GTPase activities
IX92_RS01040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX92_RS01045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IX92_RS01055	COG1137	ATPase activity
IX92_RS01060	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IX92_RS01070	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IX92_RS01075	COG0517	IMP dehydrogenase activity
IX92_RS01075	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IX92_RS01085	COG1127	ABC transporter
IX92_RS01090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IX92_RS01095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IX92_RS01100	COG2854	intermembrane phospholipid transfer
IX92_RS01110	COG5007	Belongs to the BolA IbaG family
IX92_RS01120	COG0204	Acyl-transferase
IX92_RS01125	COG2235	arginine
IX92_RS01145	COG0589	response to stress
IX92_RS01155	COG2358	TRAP transporter, solute receptor (TAXI family
IX92_RS01160	COG1438	arginine binding
IX92_RS01165	COG0039	L-malate dehydrogenase activity
IX92_RS01175	COG0251	oxidation-reduction process
IX92_RS01180	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IX92_RS01195	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IX92_RS01210	COG0564	pseudouridine synthase activity
IX92_RS01215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IX92_RS01225	COG4269	membrane
IX92_RS01235	COG0525	valine-tRNA ligase activity
IX92_RS01240	COG2927	DNA polymerase III (CHI subunit)
IX92_RS01250	COG0795	lipopolysaccharide-transporting ATPase activity
IX92_RS01255	COG0795	lipopolysaccharide-transporting ATPase activity
IX92_RS01260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IX92_RS01265	COG1546	Belongs to the CinA family
IX92_RS01270	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IX92_RS01275	COG2137	regulation of response to DNA damage stimulus
IX92_RS01285	COG0527	aspartate kinase activity
IX92_RS01335	COG3630	sodium ion export across plasma membrane
IX92_RS01340	COG0511	ligase activity, forming carbon-carbon bonds
IX92_RS01340	COG5016	pyruvate
IX92_RS01345	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
IX92_RS01355	COG1238	metal cluster binding
IX92_RS01360	COG0612	Peptidase, M16
IX92_RS01365	COG2918	glutathione biosynthetic process
IX92_RS01375	COG1854	S-ribosylhomocysteine lyase activity
IX92_RS01390	COG0582	viral genome integration into host DNA
IX92_RS01425	COG0328	RNA-DNA hybrid ribonuclease activity
IX92_RS01455	COG2197	response regulator
IX92_RS01460	COG4251	negative regulation of phosphorylation
IX92_RS01485	COG0328	RNA-DNA hybrid ribonuclease activity
IX92_RS01525	COG2003	Belongs to the UPF0758 family
IX92_RS01535	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IX92_RS01560	COG3437	response regulator, receiver
IX92_RS01620	COG0473	3-isopropylmalate dehydrogenase activity
IX92_RS01625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IX92_RS01645	COG0583	DNA-binding transcription factor activity
IX92_RS01650	COG1022	Amp-dependent synthetase and ligase
IX92_RS01655	COG0028	Belongs to the TPP enzyme family
IX92_RS01660	COG0440	acetolactate synthase activity
IX92_RS01665	COG0584	glycerophosphoryl diester phosphodiesterase
IX92_RS01670	COG2271	Major facilitator Superfamily
IX92_RS01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IX92_RS01685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IX92_RS01690	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IX92_RS01695	COG3079	Belongs to the UPF0149 family
IX92_RS01700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX92_RS01705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX92_RS01735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IX92_RS01740	COG1595	DNA-templated transcription, initiation
IX92_RS01750	COG3026	antisigma factor binding
IX92_RS01755	COG3086	response to oxidative stress
IX92_RS01760	COG0481	GTPase activity
IX92_RS01770	COG0571	ribonuclease III activity
IX92_RS01775	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IX92_RS01780	COG1381	Involved in DNA repair and RecF pathway recombination
IX92_RS01785	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IX92_RS01790	COG0736	holo-[acyl-carrier-protein] synthase activity
IX92_RS01795	COG3850	Histidine kinase
IX92_RS01795	COG4999	Histidine kinase
IX92_RS01795	COG2205	protein histidine kinase activity
IX92_RS01795	COG3437	response regulator, receiver
IX92_RS01800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IX92_RS01805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IX92_RS01810	COG3956	TIGRFAM MazG family protein
IX92_RS01820	COG0148	phosphopyruvate hydratase activity
IX92_RS01825	COG0148	phosphopyruvate hydratase activity
IX92_RS01830	COG0148	phosphopyruvate hydratase activity
IX92_RS01835	COG0617	tRNA 3'-terminal CCA addition
IX92_RS01840	COG3409	Peptidoglycan-binding domain 1 protein
IX92_RS01840	COG3267	Type II secretory pathway component ExeA
IX92_RS01850	COG4991	sh3 domain protein
IX92_RS01855	COG0306	phosphate transporter
IX92_RS01860	COG1392	Phosphate transport regulator
IX92_RS01865	COG3025	triphosphatase activity
IX92_RS01870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IX92_RS01880	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IX92_RS01885	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IX92_RS01885	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IX92_RS01890	COG0745	RESPONSE REGULATOR receiver
IX92_RS01900	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IX92_RS01915	COG0083	homoserine kinase activity
IX92_RS01920	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IX92_RS01925	COG2860	membrane
IX92_RS01930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IX92_RS01935	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IX92_RS01945	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IX92_RS01960	COG1846	Transcriptional regulator
IX92_RS01965	COG0534	Mate efflux family protein
IX92_RS01970	COG2204	response regulator
IX92_RS01980	COG0667	Aldo Keto reductase
IX92_RS01990	COG3066	DNA modification
IX92_RS01995	COG0494	nUDIX hydrolase
IX92_RS02005	COG0730	response to heat
IX92_RS02010	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IX92_RS02015	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IX92_RS02020	COG1283	sodium-dependent phosphate transmembrane transporter activity
IX92_RS02030	COG0583	DNA-binding transcription factor activity
IX92_RS02035	COG0640	Transcriptional regulator
IX92_RS02040	COG0268	Binds directly to 16S ribosomal RNA
IX92_RS02045	COG0728	peptidoglycan biosynthetic process
IX92_RS02050	COG0196	riboflavin kinase activity
IX92_RS02065	COG1047	Peptidyl-prolyl cis-trans
IX92_RS02070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IX92_RS02075	COG1966	Carbon starvation protein
IX92_RS02085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IX92_RS02090	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IX92_RS02105	COG1737	Transcriptional regulator
IX92_RS02110	COG1472	Belongs to the glycosyl hydrolase 3 family
IX92_RS02115	COG3279	Response regulator of the LytR AlgR family
IX92_RS02120	COG3275	phosphorelay sensor kinase activity
IX92_RS02125	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IX92_RS02130	COG1605	Chorismate mutase
IX92_RS02130	COG0287	Prephenate dehydrogenase
IX92_RS02135	COG0739	heme binding
IX92_RS02145	COG0488	(ABC) transporter
IX92_RS02150	COG0741	lytic transglycosylase activity
IX92_RS02155	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
IX92_RS02160	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
IX92_RS02165	COG5001	Diguanylate cyclase
IX92_RS02170	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IX92_RS02175	COG0077	Prephenate dehydratase
IX92_RS02175	COG1605	Chorismate mutase
IX92_RS02180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IX92_RS02185	COG0741	lytic transglycosylase activity
IX92_RS02190	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX92_RS02195	COG0564	pseudouridine synthase activity
IX92_RS02200	COG1496	oxidoreductase activity
IX92_RS02205	COG0542	response to heat
IX92_RS02245	COG0483	inositol monophosphate 1-phosphatase activity
IX92_RS02255	COG1959	2 iron, 2 sulfur cluster binding
IX92_RS02265	COG0822	iron-sulfur transferase activity
IX92_RS02285	COG0633	Ferredoxin
IX92_RS02290	COG2975	iron-sulfur cluster assembly
IX92_RS02295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IX92_RS02305	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IX92_RS02310	COG0583	DNA-binding transcription factor activity
IX92_RS02320	COG0583	DNA-binding transcription factor activity
IX92_RS02325	COG1022	Amp-dependent synthetase and ligase
IX92_RS02330	COG2169	Transcriptional regulator
IX92_RS02355	COG4964	Belongs to the GSP D family
IX92_RS02395	COG0583	DNA-binding transcription factor activity
IX92_RS02405	COG2169	Transcriptional regulator
IX92_RS02410	COG1486	melibiose metabolic process
IX92_RS02415	COG2211	Major facilitator Superfamily
IX92_RS02425	COG3408	Glycogen debranching enzyme
IX92_RS02425	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IX92_RS02445	COG0531	amino acid
IX92_RS02450	COG2731	YhcH YjgK YiaL family protein
IX92_RS02455	COG3250	beta-galactosidase activity
IX92_RS02460	COG1609	Transcriptional regulator
IX92_RS02465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IX92_RS02470	COG1085	galactose-1-phosphate uridylyltransferase
IX92_RS02480	COG2017	converts alpha-aldose to the beta-anomer
IX92_RS02490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX92_RS02500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX92_RS02500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX92_RS02500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX92_RS02505	COG2207	Transcriptional regulator
IX92_RS02515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX92_RS02525	COG2171	N-acyltransferase activity
IX92_RS02530	COG0450	alkyl hydroperoxide reductase
IX92_RS02535	COG0583	DNA-binding transcription factor activity
IX92_RS02540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IX92_RS02550	COG0517	IMP dehydrogenase activity
IX92_RS02555	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IX92_RS02565	COG1862	Preprotein translocase
IX92_RS02570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IX92_RS02575	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IX92_RS02595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IX92_RS02600	COG0826	peptidase U32
IX92_RS02610	COG0745	RESPONSE REGULATOR receiver
IX92_RS02615	COG5002	protein histidine kinase activity
IX92_RS02625	COG0248	Ppx GppA phosphatase
IX92_RS02630	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IX92_RS02635	COG0573	inorganic phosphate transmembrane transporter activity
IX92_RS02640	COG0581	inorganic phosphate transmembrane transporter activity
IX92_RS02645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IX92_RS02650	COG0704	Plays a role in the regulation of phosphate uptake
IX92_RS02665	COG3141	response to X-ray
IX92_RS02670	COG1309	transcriptional regulator
IX92_RS02675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_RS02695	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IX92_RS02700	COG1074	ATP-dependent DNA helicase activity
IX92_RS02705	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IX92_RS02725	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IX92_RS02730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IX92_RS02735	COG2166	iron-sulfur cluster assembly
IX92_RS02745	COG1426	Protein conserved in bacteria
IX92_RS02750	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IX92_RS02755	COG0124	histidyl-tRNA synthetase
IX92_RS02760	COG2976	Protein conserved in bacteria
IX92_RS02765	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX92_RS02770	COG1160	GTP binding
IX92_RS02780	COG2203	Gaf domain
IX92_RS02780	COG2199	diguanylate cyclase activity
IX92_RS02795	COG0517	IMP dehydrogenase activity
IX92_RS02795	COG0516	GMP reductase activity
IX92_RS02810	COG1584	GPR1 FUN34 yaaH family protein
IX92_RS02815	COG1115	amino acid carrier protein
IX92_RS02820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IX92_RS02840	COG2873	o-acetylhomoserine
IX92_RS02845	COG0835	chemotaxis
IX92_RS02845	COG0784	Response regulator, receiver
IX92_RS02850	COG0204	Acyl-transferase
IX92_RS02870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IX92_RS02875	COG0668	transmembrane transport
IX92_RS02915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IX92_RS02925	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IX92_RS02930	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IX92_RS02950	COG0582	viral genome integration into host DNA
IX92_RS02960	COG2867	negative regulation of translational initiation
IX92_RS02965	COG2914	Belongs to the UPF0125 (RnfH) family
IX92_RS02970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX92_RS02975	COG0497	DNA recombination
IX92_RS02980	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IX92_RS02985	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IX92_RS02990	COG1301	dicarboxylic acid transport
IX92_RS02995	COG0443	Heat shock 70 kDa protein
IX92_RS03010	COG4970	Tfp pilus assembly protein FimT
IX92_RS03030	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IX92_RS03040	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IX92_RS03045	COG0047	phosphoribosylformylglycinamidine synthase activity
IX92_RS03045	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IX92_RS03070	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IX92_RS03075	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IX92_RS03080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IX92_RS03085	COG1187	pseudouridine synthase activity
IX92_RS03090	COG2840	Smr protein MutS2
IX92_RS03115	COG3104	oligopeptide transport
IX92_RS03120	COG0367	asparagine synthase
IX92_RS03125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IX92_RS03125	COG4651	solute:proton antiporter activity
IX92_RS03130	COG1846	Transcriptional regulator
IX92_RS03130	COG1940	carbohydrate kinase activity
IX92_RS03135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IX92_RS03140	COG2190	(PTS) system
IX92_RS03140	COG1263	PTS System
IX92_RS03140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IX92_RS03170	COG0596	Alpha beta hydrolase
IX92_RS03175	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IX92_RS03180	COG0033	Phosphoglucomutase
IX92_RS03190	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IX92_RS03205	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IX92_RS03210	COG1053	succinate dehydrogenase
IX92_RS03215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IX92_RS03220	COG0567	Dehydrogenase, E1 component
IX92_RS03225	COG0508	dehydrogenase complex catalyzes the overall conversion of
IX92_RS03260	COG3098	single-species biofilm formation
IX92_RS03265	COG0564	pseudouridine synthase activity
IX92_RS03275	COG0142	geranyltranstransferase activity
IX92_RS03280	COG1722	exodeoxyribonuclease VII activity
IX92_RS03285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IX92_RS03295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IX92_RS03295	COG0301	tRNA thio-modification
IX92_RS03300	COG0583	DNA-binding transcription factor activity
IX92_RS03315	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
IX92_RS03325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IX92_RS03330	COG1611	Belongs to the LOG family
IX92_RS03345	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IX92_RS03345	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IX92_RS03355	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
IX92_RS03365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IX92_RS03370	COG1393	Belongs to the ArsC family
IX92_RS03395	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IX92_RS03400	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
IX92_RS03405	COG0437	4 iron, 4 sulfur cluster binding
IX92_RS03410	COG3301	Polysulphide reductase, NrfD
IX92_RS03415	COG1138	Cytochrome C-type biogenesis protein
IX92_RS03420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IX92_RS03425	COG4235	cytochrome complex assembly
IX92_RS03425	COG3088	subunit of a heme lyase
IX92_RS03435	COG2837	iron assimilation
IX92_RS03455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IX92_RS03465	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IX92_RS03475	COG1516	flagellar protein fliS
IX92_RS03495	COG1677	Flagellar hook-basal body complex protein FliE
IX92_RS03505	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IX92_RS03555	COG1987	bacterial-type flagellum assembly
IX92_RS03560	COG1684	flagellar biosynthetic protein fliR
IX92_RS03575	COG2890	protein-(glutamine-N5) methyltransferase activity
IX92_RS03580	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IX92_RS03590	COG2860	membrane
IX92_RS03595	COG3101	peptidyl-lysine hydroxylation
IX92_RS03625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IX92_RS03630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IX92_RS03635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IX92_RS03645	COG0101	tRNA pseudouridine synthase activity
IX92_RS03650	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IX92_RS03655	COG0285	dihydrofolate synthase activity
IX92_RS03660	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IX92_RS03665	COG1286	toxin biosynthetic process
IX92_RS03670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IX92_RS03675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IX92_RS03680	COG1121	(ABC) transporter
IX92_RS03685	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IX92_RS03690	COG4977	sequence-specific DNA binding
IX92_RS03695	COG1918	ferrous iron import across plasma membrane
IX92_RS03700	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IX92_RS03715	COG0018	arginyl-trna synthetase
IX92_RS03720	COG3102	Protein conserved in bacteria
IX92_RS03725	COG1025	Belongs to the peptidase M16 family
IX92_RS03730	COG2062	phosphohistidine phosphatase, SixA
IX92_RS03760	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IX92_RS03765	COG2198	Histidine kinase
IX92_RS03765	COG0784	Response regulator, receiver
IX92_RS03765	COG0643	Histidine kinase
IX92_RS03770	COG2201	protein-glutamate methylesterase activity
IX92_RS03775	COG1192	Involved in chromosome partitioning
IX92_RS03785	COG0835	chemotaxis
IX92_RS03795	COG4133	protoheme IX ABC transporter activity
IX92_RS03800	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IX92_RS03805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IX92_RS03810	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IX92_RS03820	COG1138	Cytochrome C-type biogenesis protein
IX92_RS03825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IX92_RS03830	COG3088	subunit of a heme lyase
IX92_RS03830	COG4235	cytochrome complex assembly
IX92_RS03840	COG2853	Lipoprotein
IX92_RS03845	COG2067	long-chain fatty acid transport protein
IX92_RS03850	COG2067	long-chain fatty acid transport protein
IX92_RS03865	COG0183	Belongs to the thiolase family
IX92_RS03875	COG0778	Nitroreductase
IX92_RS03880	COG0583	DNA-binding transcription factor activity
IX92_RS03885	COG0745	RESPONSE REGULATOR receiver
IX92_RS03895	COG2832	Protein of unknown function (DUF454)
IX92_RS03900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IX92_RS03915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IX92_RS03950	COG1653	transport
IX92_RS03955	COG1175	transmembrane transport
IX92_RS03965	COG3842	ATPase activity
IX92_RS03970	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IX92_RS03975	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IX92_RS03980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IX92_RS04015	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IX92_RS04020	COG0776	regulation of translation
IX92_RS04025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IX92_RS04030	COG1555	photosystem II stabilization
IX92_RS04040	COG0539	negative regulation of cytoplasmic translation
IX92_RS04050	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IX92_RS04055	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IX92_RS04060	COG0284	orotidine-5'-phosphate decarboxylase activity
IX92_RS04095	COG4120	Belongs to the binding-protein-dependent transport system permease family
IX92_RS04105	COG3706	GGDEF domain
IX92_RS04110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IX92_RS04130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IX92_RS04135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IX92_RS04145	COG0252	asparaginase activity
IX92_RS04150	COG0616	signal peptide processing
IX92_RS04155	COG0446	pyridine nucleotide-disulphide oxidoreductase
IX92_RS04155	COG1902	pentaerythritol trinitrate reductase activity
IX92_RS04160	COG0788	formyltetrahydrofolate deformylase activity
IX92_RS04170	COG1199	ATP-dependent helicase activity
IX92_RS04175	COG1214	PFAM Peptidase M22, glycoprotease
IX92_RS04190	COG2267	carboxylic ester hydrolase activity
IX92_RS04195	COG0318	PFAM AMP-dependent synthetase and ligase
IX92_RS04200	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IX92_RS04205	COG0659	secondary active sulfate transmembrane transporter activity
IX92_RS04210	COG1530	ribonuclease E activity
IX92_RS04215	COG0564	pseudouridine synthase activity
IX92_RS04220	COG0424	maF-like protein
IX92_RS04225	COG1399	metal-binding, possibly nucleic acid-binding protein
IX92_RS04230	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IX92_RS04240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IX92_RS04265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IX92_RS04270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IX92_RS04275	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IX92_RS04280	COG0470	DNA polymerase III
IX92_RS04285	COG0084	hydrolase, TatD family'
IX92_RS04290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IX92_RS04290	COG1263	PTS System
IX92_RS04300	COG0733	neurotransmitter:sodium symporter activity
IX92_RS04315	COG4667	esterase of the alpha-beta hydrolase superfamily
IX92_RS04320	COG0469	pyruvate kinase activity
IX92_RS04325	COG1940	carbohydrate kinase activity
IX92_RS04330	COG0835	chemotaxis
IX92_RS04330	COG0784	Response regulator, receiver
IX92_RS04350	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_RS04355	COG0616	signal peptide processing
IX92_RS04360	COG0513	Belongs to the DEAD box helicase family
IX92_RS04375	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IX92_RS04380	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IX92_RS04395	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IX92_RS04400	COG0436	Aminotransferase
IX92_RS04405	COG1169	isochorismate synthase
IX92_RS04410	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IX92_RS04415	COG0596	Alpha beta hydrolase
IX92_RS04435	COG2855	membrane
IX92_RS04440	COG0477	Major facilitator Superfamily
IX92_RS04465	COG1522	sequence-specific DNA binding
IX92_RS04480	COG1946	Acyl-CoA thioesterase
IX92_RS04485	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IX92_RS04500	COG3706	GGDEF domain
IX92_RS04520	COG1414	Transcriptional regulator
IX92_RS04525	COG0280	phosphate acetyltransferase
IX92_RS04530	COG0730	response to heat
IX92_RS04550	COG2855	membrane
IX92_RS04565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IX92_RS04570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IX92_RS04575	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IX92_RS04580	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IX92_RS04580	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IX92_RS04595	COG1472	Belongs to the glycosyl hydrolase 3 family
IX92_RS04600	COG3876	Protein conserved in bacteria
IX92_RS04605	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IX92_RS04610	COG1215	transferase activity, transferring glycosyl groups
IX92_RS04625	COG3397	chitin binding
IX92_RS04630	COG1770	oligopeptidase
IX92_RS04640	COG3227	Zinc metalloprotease (Elastase)
IX92_RS04650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_RS04660	COG0577	efflux transmembrane transporter activity
IX92_RS04670	COG1136	(ABC) transporter
IX92_RS04670	COG0577	efflux transmembrane transporter activity
IX92_RS04690	COG0330	HflC and HflK could
IX92_RS04700	COG0840	transmembrane signaling receptor activity
IX92_RS04705	COG1404	Belongs to the peptidase S8 family
IX92_RS04715	COG0840	transmembrane signaling receptor activity
IX92_RS04735	COG2067	long-chain fatty acid transport protein
IX92_RS04750	COG0601	transmembrane transport
IX92_RS04755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IX92_RS04760	COG0444	Belongs to the ABC transporter superfamily
IX92_RS04770	COG0435	Glutathione S-transferase
IX92_RS04775	COG3706	GGDEF domain
IX92_RS04780	COG0280	phosphate acetyltransferase
IX92_RS04780	COG0857	belongs to the CobB CobQ family
IX92_RS04785	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IX92_RS04790	COG3092	negative regulation of chromosome organization
IX92_RS04795	COG0686	Belongs to the AlaDH PNT family
IX92_RS04805	COG1674	ftsk spoiiie
IX92_RS04815	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IX92_RS04820	COG2186	Transcriptional regulator
IX92_RS04835	COG0537	adenosine 5'-monophosphoramidase activity
IX92_RS04865	COG1252	NADH dehydrogenase
IX92_RS04885	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IX92_RS04895	COG4591	ABC-type transport system involved in lipoprotein release permease component
IX92_RS04900	COG1136	(ABC) transporter
IX92_RS04905	COG4591	ABC-type transport system involved in lipoprotein release permease component
IX92_RS04915	COG0658	competence protein
IX92_RS04915	COG2333	competence protein COMEC
IX92_RS04920	COG1132	(ABC) transporter
IX92_RS04930	COG2835	tetraacyldisaccharide 4'-kinase activity
IX92_RS04935	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IX92_RS04940	COG2719	SpoVR family
IX92_RS04945	COG2718	Belongs to the UPF0229 family
IX92_RS04950	COG2766	serine protein kinase
IX92_RS04955	COG3713	MltA-interacting MipA family protein
IX92_RS04960	COG3013	Belongs to the UPF0304 family
IX92_RS04970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IX92_RS04985	COG1882	Formate acetyltransferase
IX92_RS05020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IX92_RS05025	COG1454	alcohol dehydrogenase
IX92_RS05025	COG1012	belongs to the aldehyde dehydrogenase family
IX92_RS05030	COG1737	Transcriptional regulator
IX92_RS05035	COG0076	glutamate decarboxylase activity
IX92_RS05045	COG2431	L-lysine efflux transmembrane transporter activity
IX92_RS05055	COG3070	regulator of competence-specific genes
IX92_RS05070	COG4191	Histidine kinase
IX92_RS05070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX92_RS05080	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IX92_RS05090	COG1032	radical SAM domain protein
IX92_RS05115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IX92_RS05120	COG1764	response to oxidative stress
IX92_RS05125	COG1846	Transcriptional regulator
IX92_RS05135	COG0583	DNA-binding transcription factor activity
IX92_RS05145	COG0673	inositol 2-dehydrogenase activity
IX92_RS05150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IX92_RS05170	COG0840	transmembrane signaling receptor activity
IX92_RS05175	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IX92_RS05190	COG3152	Membrane
IX92_RS05235	COG1858	cytochrome C peroxidase
IX92_RS05245	COG0443	Heat shock 70 kDa protein
IX92_RS05290	COG1643	Atp-dependent helicase
IX92_RS05300	COG1301	dicarboxylic acid transport
IX92_RS05305	COG0159	tryptophan synthase activity
IX92_RS05315	COG0135	phosphoribosylanthranilate isomerase activity
IX92_RS05315	COG0134	indole-3-glycerol-phosphate synthase activity
IX92_RS05320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IX92_RS05325	COG0512	Glutamine amidotransferase of anthranilate synthase
IX92_RS05330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IX92_RS05340	COG0613	PHP domain protein
IX92_RS05345	COG0009	L-threonylcarbamoyladenylate synthase
IX92_RS05360	COG1187	pseudouridine synthase activity
IX92_RS05365	COG0384	phenazine biosynthesis protein PhzF
IX92_RS05375	COG2814	Major facilitator Superfamily
IX92_RS05380	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IX92_RS05385	COG4988	ABC transporter
IX92_RS05390	COG0492	ferredoxin-NADP+ reductase activity
IX92_RS05405	COG2175	clavaminate synthase activity
IX92_RS05420	COG0612	Peptidase, M16
IX92_RS05430	COG2949	membrane
IX92_RS05440	COG0281	malic enzyme
IX92_RS05445	COG1643	Atp-dependent helicase
IX92_RS05460	COG1448	Aminotransferase
IX92_RS05465	COG2770	Histidine kinase
IX92_RS05465	COG3437	response regulator, receiver
IX92_RS05475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX92_RS05485	COG0017	Asparaginyl-tRNA synthetase
IX92_RS05490	COG0840	transmembrane signaling receptor activity
IX92_RS05500	COG0814	amino acid
IX92_RS05510	COG1760	l-serine dehydratase
IX92_RS05515	COG0814	amino acid
IX92_RS05520	COG0494	nUDIX hydrolase
IX92_RS05530	COG0784	Response regulator, receiver
IX92_RS05530	COG2205	protein histidine kinase activity
IX92_RS05550	COG3106	COG3106 Predicted ATPase
IX92_RS05565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IX92_RS05585	COG3706	GGDEF domain
IX92_RS05595	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IX92_RS05620	COG2989	Protein conserved in bacteria
IX92_RS05625	COG3108	Peptidase M15
IX92_RS05630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX92_RS05645	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IX92_RS05680	COG4667	esterase of the alpha-beta hydrolase superfamily
IX92_RS05685	COG0783	Belongs to the Dps family
IX92_RS05695	COG0531	amino acid
IX92_RS05700	COG2962	Rard protein
IX92_RS05710	COG0791	NLP P60 protein
IX92_RS05900	COG4628	conserved protein (DUF2132)
IX92_RS05910	COG0456	acetyltransferase
IX92_RS05930	COG0730	response to heat
IX92_RS05940	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_RS05950	COG2824	Alkylphosphonate utilization operon protein PhnA
IX92_RS05965	COG0456	acetyltransferase
IX92_RS05985	COG3040	lipid binding
IX92_RS06000	COG3122	Protein conserved in bacteria
IX92_RS06055	COG0454	-acetyltransferase
IX92_RS06060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IX92_RS06085	COG0456	acetyltransferase
IX92_RS06095	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IX92_RS06100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IX92_RS06115	COG2195	Cleaves the N-terminal amino acid of tripeptides
IX92_RS06125	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IX92_RS06135	COG0625	glutathione transferase activity
IX92_RS06150	COG2885	chlorophyll binding
IX92_RS06165	COG0277	FAD linked oxidase domain protein
IX92_RS06165	COG0247	lactate metabolic process
IX92_RS06180	COG2986	histidine ammonia-lyase
IX92_RS06190	COG0010	Belongs to the arginase family
IX92_RS06195	COG1228	amidohydrolase
IX92_RS06200	COG2188	Transcriptional regulator
IX92_RS06205	COG4326	sporulation control protein
IX92_RS06225	COG0500	methyltransferase
IX92_RS06230	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IX92_RS06240	COG0295	cytidine deaminase activity
IX92_RS06245	COG1346	cytolysis
IX92_RS06250	COG1380	Effector of murein hydrolase LrgA
IX92_RS06255	COG2925	Exonuclease
IX92_RS06290	COG1823	symporter activity
IX92_RS06295	COG0702	epimerase
IX92_RS06300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IX92_RS06305	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IX92_RS06310	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IX92_RS06320	COG0406	alpha-ribazole phosphatase activity
IX92_RS06335	COG4139	cobalamin transport
IX92_RS06340	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
IX92_RS06365	COG2814	Major facilitator Superfamily
IX92_RS06375	COG1119	ATPase activity
IX92_RS06385	COG5002	protein histidine kinase activity
IX92_RS06385	COG0784	Response regulator, receiver
IX92_RS06455	COG1451	nucleotide metabolic process
IX92_RS06470	COG3063	Type IV pilus biogenesis stability protein PilW
IX92_RS06475	COG0596	Alpha beta hydrolase
IX92_RS06475	COG0508	dehydrogenase complex catalyzes the overall conversion of
IX92_RS06480	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IX92_RS06495	COG4251	negative regulation of phosphorylation
IX92_RS06495	COG2203	Gaf domain
IX92_RS06495	COG3706	GGDEF domain
IX92_RS06495	COG5001	Diguanylate cyclase
IX92_RS06510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_RS06535	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IX92_RS06540	COG0515	serine threonine protein kinase
IX92_RS06660	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IX92_RS06665	COG0372	Belongs to the citrate synthase family
IX92_RS06675	COG2828	Protein conserved in bacteria
IX92_RS06695	COG0561	phosphatase activity
IX92_RS06700	COG0602	queuosine metabolic process
IX92_RS06730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IX92_RS06735	COG0840	transmembrane signaling receptor activity
IX92_RS06740	COG1254	Belongs to the acylphosphatase family
IX92_RS06745	COG2920	part of a sulfur-relay system
IX92_RS06750	COG0670	Belongs to the BI1 family
IX92_RS06755	COG1126	abc transporter atp-binding protein
IX92_RS06760	COG0765	amino acid transport
IX92_RS06765	COG4597	amino acid ABC transporter
IX92_RS06770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX92_RS06785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IX92_RS06790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IX92_RS06810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IX92_RS06810	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
IX92_RS06815	COG3008	intermembrane lipid transfer
IX92_RS06820	COG2995	paraquat-inducible protein a
IX92_RS06825	COG1132	(ABC) transporter
IX92_RS06830	COG1956	GAF domain-containing protein
IX92_RS06835	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IX92_RS06850	COG0308	aminopeptidase N
IX92_RS06865	COG0167	dihydroorotate dehydrogenase activity
IX92_RS06885	COG0488	(ABC) transporter
IX92_RS06900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IX92_RS06905	COG1067	ATP-dependent peptidase activity
IX92_RS06965	COG0789	Transcriptional regulator
IX92_RS07085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IX92_RS07090	COG0840	transmembrane signaling receptor activity
IX92_RS07240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX92_RS07365	COG3278	Belongs to the heme-copper respiratory oxidase family
IX92_RS07380	COG2010	Cytochrome c
IX92_RS07390	COG2217	Heavy metal translocating P-type atpase
IX92_RS07405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IX92_RS07410	COG0589	response to stress
IX92_RS07435	COG3842	ATPase activity
IX92_RS07445	COG1177	transmembrane transport
IX92_RS07450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IX92_RS07455	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IX92_RS07460	COG2199	diguanylate cyclase activity
IX92_RS07465	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IX92_RS07470	COG0004	ammonium transporteR
IX92_RS07485	COG0437	4 iron, 4 sulfur cluster binding
IX92_RS07490	COG0243	molybdopterin cofactor binding
IX92_RS07490	COG3383	formate dehydrogenase (NAD+) activity
IX92_RS07520	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IX92_RS07530	COG3038	cytochrome b561
IX92_RS07560	COG0583	DNA-binding transcription factor activity
IX92_RS07570	COG0583	DNA-binding transcription factor activity
IX92_RS07575	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IX92_RS07595	COG0069	glutamate synthase activity
IX92_RS07610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX92_RS07615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_RS07625	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_RS07640	COG0488	(ABC) transporter
IX92_RS07650	COG1595	DNA-templated transcription, initiation
IX92_RS07665	COG3852	Histidine kinase
IX92_RS07680	COG4662	Binding-protein-dependent transport system inner membrane component
IX92_RS07685	COG3842	ATPase activity
IX92_RS07690	COG0746	molybdenum cofactor guanylyltransferase activity
IX92_RS07695	COG0303	'Molybdopterin
IX92_RS07725	COG1940	carbohydrate kinase activity
IX92_RS07730	COG3148	PFAM DTW domain containing protein
IX92_RS07740	COG0840	transmembrane signaling receptor activity
IX92_RS07745	COG0791	NLP P60 protein
IX92_RS07755	COG3001	Fructosamine kinase
IX92_RS07765	COG0307	riboflavin synthase, alpha
IX92_RS07770	COG0534	Mate efflux family protein
IX92_RS07815	COG2204	response regulator
IX92_RS07825	COG0438	transferase activity, transferring glycosyl groups
IX92_RS07830	COG0438	transferase activity, transferring glycosyl groups
IX92_RS07860	COG0297	glycogen (starch) synthase activity
IX92_RS07870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IX92_RS07905	COG4774	siderophore transport
IX92_RS07925	COG4615	Cyclic peptide transporter
IX92_RS07935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IX92_RS07940	COG1120	ATPase activity
IX92_RS07945	COG2977	Belongs to the P-Pant transferase superfamily
IX92_RS07950	COG1929	Belongs to the glycerate kinase type-1 family
IX92_RS07955	COG3835	regulator
IX92_RS07965	COG2814	Major facilitator Superfamily
IX92_RS07975	COG1288	antiporter activity
IX92_RS07985	COG2186	Transcriptional regulator
IX92_RS07995	COG3713	MltA-interacting MipA family protein
IX92_RS08005	COG0745	RESPONSE REGULATOR receiver
IX92_RS08015	COG0583	DNA-binding transcription factor activity
IX92_RS08035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IX92_RS08055	COG2116	formate transmembrane transporter activity
IX92_RS08065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX92_RS08075	COG2199	diguanylate cyclase activity
IX92_RS08095	COG4565	transcriptional regulatory protein
IX92_RS08100	COG3290	protein histidine kinase activity
IX92_RS08120	COG0848	biopolymer transport protein
IX92_RS08125	COG0811	peptide transport
IX92_RS08130	COG0811	peptide transport
IX92_RS08145	COG2205	protein histidine kinase activity
IX92_RS08150	COG0745	RESPONSE REGULATOR receiver
IX92_RS08155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX92_RS08195	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IX92_RS08200	COG1328	CTP reductase activity
IX92_RS08205	COG0840	transmembrane signaling receptor activity
IX92_RS08215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IX92_RS08220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IX92_RS08225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IX92_RS08230	COG0633	Ferredoxin
IX92_RS08255	COG0019	diaminopimelate decarboxylase activity
IX92_RS08295	COG0577	efflux transmembrane transporter activity
IX92_RS08300	COG1136	(ABC) transporter
IX92_RS08305	COG0534	Mate efflux family protein
IX92_RS08310	COG0702	epimerase
IX92_RS08320	COG2814	Major facilitator Superfamily
IX92_RS08330	COG1061	Type III restriction enzyme res subunit
IX92_RS08370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX92_RS08375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_RS08395	COG0463	Glycosyl transferase, family 2
IX92_RS08405	COG2188	Transcriptional regulator
IX92_RS08410	COG1263	PTS System
IX92_RS08410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IX92_RS08415	COG1621	beta-fructofuranosidase activity
IX92_RS08425	COG0583	DNA-binding transcription factor activity
IX92_RS08430	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IX92_RS08460	COG4221	oxidoreductase activity
IX92_RS08490	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IX92_RS08495	COG0307	riboflavin synthase, alpha
IX92_RS08545	COG0242	peptide deformylase activity
IX92_RS08550	COG0519	Catalyzes the synthesis of GMP from XMP
IX92_RS08565	COG4580	involved in the transport of maltose and maltodextrins
IX92_RS08570	COG0778	Nitroreductase
IX92_RS08630	COG3300	MHYT domain
IX92_RS08630	COG5001	Diguanylate cyclase
IX92_RS08665	COG1115	amino acid carrier protein
IX92_RS08670	COG1280	lysine exporter protein (LysE YggA)
IX92_RS08675	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IX92_RS08680	COG0352	thiamine-phosphate diphosphorylase activity
IX92_RS08685	COG0583	DNA-binding transcription factor activity
IX92_RS08710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IX92_RS08720	COG1012	belongs to the aldehyde dehydrogenase family
IX92_RS08730	COG0583	DNA-binding transcription factor activity
IX92_RS08770	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IX92_RS08780	COG1609	Transcriptional regulator
IX92_RS08785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IX92_RS08795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IX92_RS08795	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IX92_RS08810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IX92_RS08815	COG1609	Transcriptional regulator
IX92_RS08825	COG0642	Histidine kinase
IX92_RS08830	COG0745	RESPONSE REGULATOR receiver
IX92_RS08850	COG1858	cytochrome C peroxidase
IX92_RS08855	COG2205	protein histidine kinase activity
IX92_RS08855	COG0784	Response regulator, receiver
IX92_RS08860	COG2205	protein histidine kinase activity
IX92_RS08860	COG0784	Response regulator, receiver
IX92_RS08865	COG0488	(ABC) transporter
IX92_RS08870	COG3437	response regulator, receiver
IX92_RS08880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IX92_RS08895	COG1216	Glycosyl transferase, family 2
IX92_RS08905	COG0673	inositol 2-dehydrogenase activity
IX92_RS08910	COG3718	enzyme involved in inositol metabolism
IX92_RS08935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IX92_RS08940	COG0673	inositol 2-dehydrogenase activity
IX92_RS08945	COG3962	Belongs to the TPP enzyme family
IX92_RS08955	COG0477	Major facilitator Superfamily
IX92_RS08955	COG2814	Major facilitator Superfamily
IX92_RS08975	COG0183	Belongs to the thiolase family
IX92_RS08980	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IX92_RS09020	COG3962	Belongs to the TPP enzyme family
IX92_RS09025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IX92_RS09035	COG1129	ABC transporter
IX92_RS09040	COG4211	Belongs to the binding-protein-dependent transport system permease family
IX92_RS09050	COG0277	FAD linked oxidase domain protein
IX92_RS09060	COG0583	DNA-binding transcription factor activity
IX92_RS09080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IX92_RS09085	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IX92_RS09105	COG1621	beta-fructofuranosidase activity
IX92_RS09120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IX92_RS09120	COG1263	PTS System
IX92_RS09125	COG1335	isochorismatase
IX92_RS09130	COG1741	Belongs to the pirin family
IX92_RS09175	COG0072	phenylalanine-tRNA ligase activity
IX92_RS09175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX92_RS09185	COG3706	GGDEF domain
IX92_RS09210	COG2133	pyrroloquinoline quinone binding
IX92_RS09220	COG1902	pentaerythritol trinitrate reductase activity
IX92_RS09250	COG0322	excinuclease ABC activity
IX92_RS09255	COG2197	response regulator
IX92_RS09270	COG0417	DNA replication proofreading
IX92_RS09285	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IX92_RS09295	COG0776	regulation of translation
IX92_RS09330	COG2350	Protein conserved in bacteria
IX92_RS09345	COG3313	Fe-S protein
IX92_RS09355	COG4134	Bacterial extracellular solute-binding protein
IX92_RS09360	COG4135	transport system, permease component
IX92_RS09365	COG4136	ATPase activity
IX92_RS09370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IX92_RS09375	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IX92_RS09380	COG0564	pseudouridine synthase activity
IX92_RS09385	COG0733	neurotransmitter:sodium symporter activity
IX92_RS09395	COG0626	cystathionine gamma-synthase activity
IX92_RS09400	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IX92_RS09405	COG5380	lipid catabolic process
IX92_RS09410	COG2818	Glycosylase
IX92_RS09430	COG1983	PspC domain protein
IX92_RS09440	COG1842	Phage shock protein A
IX92_RS09445	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IX92_RS09460	COG4171	peptide transport system, permease
IX92_RS09470	COG4172	Belongs to the ABC transporter superfamily
IX92_RS09485	COG1227	inorganic diphosphatase activity
IX92_RS09495	COG0217	transcriptional regulatory protein
IX92_RS09500	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IX92_RS09500	COG0140	phosphoribosyl-ATP diphosphatase activity
IX92_RS09510	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IX92_RS09515	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IX92_RS09520	COG0131	Imidazoleglycerol-phosphate dehydratase
IX92_RS09520	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IX92_RS09530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IX92_RS09540	COG1757	Na H antiporter
IX92_RS09550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IX92_RS09560	COG0482	sulfurtransferase activity
IX92_RS09570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IX92_RS09580	COG2268	Band 7 protein
IX92_RS09590	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IX92_RS09615	COG0501	Belongs to the peptidase M48B family
IX92_RS09620	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IX92_RS09625	COG1073	alpha beta
IX92_RS09625	COG2226	methyltransferase
IX92_RS09630	COG0156	8-amino-7-oxononanoate synthase activity
IX92_RS09640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IX92_RS09655	COG1199	ATP-dependent helicase activity
IX92_RS09660	COG0730	response to heat
IX92_RS09675	COG2850	peptidyl-arginine hydroxylation
IX92_RS09680	COG0840	transmembrane signaling receptor activity
IX92_RS09685	COG0708	Exodeoxyribonuclease III
IX92_RS09690	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IX92_RS09695	COG1960	acyl-CoA dehydrogenase activity
IX92_RS09715	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IX92_RS09720	COG0463	Glycosyl transferase, family 2
IX92_RS09725	COG0745	RESPONSE REGULATOR receiver
IX92_RS09730	COG3850	Histidine kinase
IX92_RS09730	COG5002	protein histidine kinase activity
IX92_RS09745	COG1940	carbohydrate kinase activity
IX92_RS09760	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IX92_RS09765	COG1881	PFAM PEBP family protein
IX92_RS09770	COG1902	pentaerythritol trinitrate reductase activity
IX92_RS09790	COG5002	protein histidine kinase activity
IX92_RS09790	COG0784	Response regulator, receiver
IX92_RS09810	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IX92_RS09815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IX92_RS09820	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IX92_RS09825	COG2885	chlorophyll binding
IX92_RS09830	COG0823	Involved in the tonB-independent uptake of proteins
IX92_RS09845	COG0811	peptide transport
IX92_RS09850	COG0824	Thioesterase
IX92_RS09865	COG1294	oxidase, subunit
IX92_RS09870	COG1271	oxidase subunit
IX92_RS09875	COG2255	four-way junction helicase activity
IX92_RS09880	COG0632	four-way junction helicase activity
IX92_RS09885	COG0840	transmembrane signaling receptor activity
IX92_RS09890	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IX92_RS09910	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_RS09925	COG0243	molybdopterin cofactor binding
IX92_RS09930	COG3005	denitrification pathway
IX92_RS09935	COG4459	periplasmic nitrate reductase
IX92_RS09940	COG0390	transport system, permease component
IX92_RS09945	COG2116	formate transmembrane transporter activity
IX92_RS09970	COG0542	response to heat
IX92_RS09975	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IX92_RS09980	COG1278	Cold shock
IX92_RS09990	COG1187	pseudouridine synthase activity
IX92_RS10000	COG1801	Protein of unknown function DUF72
IX92_RS10010	COG0500	methyltransferase
IX92_RS10015	COG0189	ligase activity
IX92_RS10015	COG4067	protein conserved in archaea
IX92_RS10045	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IX92_RS10050	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IX92_RS10060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IX92_RS10065	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IX92_RS10070	COG0745	RESPONSE REGULATOR receiver
IX92_RS10085	COG3070	regulator of competence-specific genes
IX92_RS10105	COG0297	glycogen (starch) synthase activity
IX92_RS10110	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IX92_RS10115	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IX92_RS10125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IX92_RS10135	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IX92_RS10140	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IX92_RS10145	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IX92_RS10150	COG1435	thymidine kinase activity
IX92_RS10155	COG0215	cysteine-tRNA ligase activity
IX92_RS10160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IX92_RS10165	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IX92_RS10170	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IX92_RS10175	COG3012	SEC-C Motif Domain Protein
IX92_RS10180	COG3139	Protein of unknown function (DUF1315)
IX92_RS10190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IX92_RS10205	COG0840	transmembrane signaling receptor activity
IX92_RS10210	COG2226	methyltransferase
IX92_RS10225	COG1785	Belongs to the alkaline phosphatase family
IX92_RS10245	COG0668	transmembrane transport
IX92_RS10250	COG2983	Belongs to the UPF0260 family
IX92_RS10260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IX92_RS10265	COG0583	DNA-binding transcription factor activity
IX92_RS10270	COG2951	lytic endotransglycosylase activity
IX92_RS10275	COG3100	YcgL domain-containing protein
IX92_RS10280	COG0850	regulation of cytokinetic process
IX92_RS10285	COG2894	cell division
IX92_RS10290	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IX92_RS10295	COG1454	alcohol dehydrogenase
IX92_RS10295	COG1012	belongs to the aldehyde dehydrogenase family
IX92_RS10300	COG2095	MarC family integral membrane protein
IX92_RS10305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IX92_RS10310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IX92_RS10315	COG1757	Na H antiporter
IX92_RS10335	COG3081	Nucleoid-associated protein
IX92_RS10340	COG3082	Protein of unknown function (DUF1414)
IX92_RS10345	COG3083	sulfuric ester hydrolase activity
IX92_RS10380	COG3852	Histidine kinase
IX92_RS10410	COG0123	including yeast histone deacetylase and acetoin utilization protein
IX92_RS10420	COG1881	PFAM PEBP family protein
IX92_RS10430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IX92_RS10435	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IX92_RS10455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IX92_RS10460	COG0302	gtp cyclohydrolase
IX92_RS10460	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IX92_RS10465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IX92_RS10470	COG0302	gtp cyclohydrolase
IX92_RS10480	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IX92_RS10490	COG2982	Protein involved in outer membrane biogenesis
IX92_RS10495	COG0572	uridine kinase
IX92_RS10500	COG0489	protein tyrosine kinase activity
IX92_RS10505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX92_RS10505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX92_RS10545	COG0617	tRNA 3'-terminal CCA addition
IX92_RS10545	COG0517	IMP dehydrogenase activity
IX92_RS10545	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IX92_RS10555	COG3706	GGDEF domain
IX92_RS10560	COG0314	molybdopterin synthase activity
IX92_RS10565	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IX92_RS10575	COG0521	Mo-molybdopterin cofactor biosynthetic process
IX92_RS10580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IX92_RS10585	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IX92_RS10590	COG2198	Histidine kinase
IX92_RS10600	COG0556	nucleotide-excision repair
IX92_RS10615	COG0739	heme binding
IX92_RS10660	COG2885	chlorophyll binding
IX92_RS10680	COG1987	bacterial-type flagellum assembly
IX92_RS10690	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IX92_RS10705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IX92_RS10710	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IX92_RS10715	COG1516	flagellar protein fliS
IX92_RS10730	COG1580	Controls the rotational direction of flagella during chemotaxis
IX92_RS10735	COG1191	sigma factor activity
IX92_RS10740	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IX92_RS10745	COG1360	Flagellar Motor Protein
IX92_RS10775	COG1706	bacterial-type flagellum-dependent cell motility
IX92_RS10780	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IX92_RS10785	COG4786	Flagellar basal body rod
IX92_RS10790	COG4787	bacterial-type flagellum-dependent cell motility
IX92_RS10795	COG1749	Flagellar hook protein flgE
IX92_RS10805	COG1558	bacterial-type flagellum-dependent cell motility
IX92_RS10810	COG1815	bacterial-type flagellum-dependent cell motility
IX92_RS10830	COG1388	LysM domain
IX92_RS10830	COG0741	lytic transglycosylase activity
IX92_RS10835	COG4657	Part of a membrane complex involved in electron transport
IX92_RS10845	COG4656	Part of a membrane complex involved in electron transport
IX92_RS10850	COG4658	electron transport chain
IX92_RS10855	COG4659	FMN binding
IX92_RS10860	COG4660	Part of a membrane complex involved in electron transport
IX92_RS10865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IX92_RS10895	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IX92_RS10935	COG3384	dioxygenase
IX92_RS10965	COG0346	lactoylglutathione lyase activity
IX92_RS10985	COG2056	Na+-H+ antiporter family
IX92_RS10990	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IX92_RS11000	COG2716	regulation of RNA biosynthetic process
IX92_RS11005	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IX92_RS11025	COG4783	chaperone-mediated protein folding
IX92_RS11030	COG1393	Belongs to the ArsC family
IX92_RS11055	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IX92_RS11065	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IX92_RS11070	COG2912	Transglutaminase-like superfamily
IX92_RS11080	COG2890	protein-(glutamine-N5) methyltransferase activity
IX92_RS11100	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IX92_RS11105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IX92_RS11115	COG0012	GTP binding
IX92_RS11225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IX92_RS11230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IX92_RS11235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IX92_RS11245	COG1705	Flagellar rod assembly protein muramidase FlgJ
IX92_RS11245	COG3951	Flagellar rod assembly protein muramidase FlgJ
IX92_RS11250	COG1706	bacterial-type flagellum-dependent cell motility
IX92_RS11255	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IX92_RS11265	COG4787	bacterial-type flagellum-dependent cell motility
IX92_RS11285	COG1815	bacterial-type flagellum-dependent cell motility
IX92_RS11290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IX92_RS11295	COG0784	Response regulator, receiver
IX92_RS11295	COG0835	chemotaxis
IX92_RS11305	COG2747	anti-sigma28 factor FlgM
IX92_RS11345	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IX92_RS11355	COG2194	sulfuric ester hydrolase activity
IX92_RS11395	COG2608	mercury ion transmembrane transporter activity
IX92_RS11395	COG2217	Heavy metal translocating P-type atpase
IX92_RS11415	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IX92_RS11425	COG0326	Molecular chaperone. Has ATPase activity
IX92_RS11430	COG3710	Transcriptional regulator
IX92_RS11450	COG0622	Phosphoesterase
IX92_RS11475	COG1090	epimerase
IX92_RS11480	COG0300	oxidoreductase activity
IX92_RS11485	COG3118	belongs to the thioredoxin family
IX92_RS11490	COG0330	HflC and HflK could
IX92_RS11510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IX92_RS11515	COG3115	cell septum assembly
IX92_RS11520	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
IX92_RS11525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IX92_RS11530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX92_RS11535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IX92_RS11540	COG2190	(PTS) system
IX92_RS11545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX92_RS11555	COG1702	phosphate starvation-inducible protein PhoH
IX92_RS11560	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IX92_RS11565	COG4535	Mg2 and Co2 transporter CorC
IX92_RS11570	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IX92_RS11575	COG2888	peptidyl-tyrosine sulfation
IX92_RS11580	COG0495	leucyl-tRNA aminoacylation
IX92_RS11585	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
IX92_RS11590	COG1466	dna polymerase III delta subunit
IX92_RS11595	COG0799	negative regulation of ribosome biogenesis
IX92_RS11600	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IX92_RS11605	COG0768	penicillin binding
IX92_RS11610	COG0772	Belongs to the SEDS family
IX92_RS11615	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IX92_RS11620	COG1686	Belongs to the peptidase S11 family
IX92_RS11625	COG2921	Belongs to the UPF0250 family
IX92_RS11635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IX92_RS11650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IX92_RS11660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX92_RS11665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_RS11690	COG0366	Alpha amylase catalytic
IX92_RS11695	COG1263	PTS System
IX92_RS11695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IX92_RS11700	COG1609	Transcriptional regulator
IX92_RS11710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IX92_RS11715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IX92_RS11720	COG2011	ABC-type metal ion transport system permease component
IX92_RS11725	COG1464	Belongs to the NlpA lipoprotein family
IX92_RS11735	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IX92_RS11740	COG0254	rRNA binding
IX92_RS11745	COG1720	tRNA m6t6A37 methyltransferase activity
IX92_RS11755	COG0121	glutamine amidotransferase
IX92_RS11760	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IX92_RS11765	COG1960	acyl-CoA dehydrogenase activity
IX92_RS11780	COG0328	RNA-DNA hybrid ribonuclease activity
IX92_RS11785	COG2226	methyltransferase
IX92_RS11790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX92_RS11795	COG1388	LysM domain
IX92_RS11795	COG0741	lytic transglycosylase activity
IX92_RS11805	COG3021	interspecies interaction between organisms
IX92_RS11810	COG0347	Belongs to the P(II) protein family
IX92_RS11820	COG0037	tRNA processing
IX92_RS11825	COG0825	malonyl-CoA metabolic process
IX92_RS11830	COG0587	DNA-directed DNA polymerase activity
IX92_RS11835	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IX92_RS11850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IX92_RS11855	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IX92_RS11860	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IX92_RS11865	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX92_RS11870	COG0750	zinc metalloprotease
IX92_RS11880	COG0575	Belongs to the CDS family
IX92_RS11885	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IX92_RS11890	COG0233	cytoplasmic translational termination
IX92_RS11895	COG0528	UMP kinase activity
IX92_RS11900	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IX92_RS11905	COG0052	Belongs to the universal ribosomal protein uS2 family
IX92_RS11910	COG0024	Methionine aminopeptidase
IX92_RS11925	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IX92_RS11930	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IX92_RS11935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IX92_RS11955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IX92_RS11955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IX92_RS11960	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IX92_RS11965	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IX92_RS11970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IX92_RS11980	COG1073	alpha beta
IX92_RS11985	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IX92_RS11990	COG2252	PERMEase
IX92_RS11995	COG2195	Cleaves the N-terminal amino acid of tripeptides
IX92_RS12000	COG4067	protein conserved in archaea
IX92_RS12000	COG0189	ligase activity
IX92_RS12005	COG0189	ligase activity
IX92_RS12015	COG0733	neurotransmitter:sodium symporter activity
IX92_RS12030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IX92_RS12035	COG0514	ATP-dependent DNA helicase (RecQ)
IX92_RS12040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IX92_RS12055	COG1477	protein flavinylation
IX92_RS12060	COG2871	sodium ion transport
IX92_RS12065	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IX92_RS12080	COG1805	sodium ion transport
IX92_RS12085	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IX92_RS12090	COG0271	Belongs to the BolA IbaG family
IX92_RS12095	COG2813	Specifically methylates the guanine in position
IX92_RS12105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IX92_RS12120	COG1595	DNA-templated transcription, initiation
IX92_RS12130	COG3248	Nucleoside-binding outer membrane protein
IX92_RS12135	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IX92_RS12140	COG0693	protein deglycase activity
IX92_RS12145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IX92_RS12150	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IX92_RS12160	COG0560	Phosphoserine phosphatase
IX92_RS12170	COG0813	purine-nucleoside phosphorylase activity
IX92_RS12175	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IX92_RS12180	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IX92_RS12195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IX92_RS12200	COG0084	hydrolase, TatD family'
IX92_RS12205	COG3022	response to hydroperoxide
IX92_RS12210	COG1115	amino acid carrier protein
IX92_RS12225	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IX92_RS12230	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IX92_RS12235	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
IX92_RS12240	COG0583	DNA-binding transcription factor activity
IX92_RS12245	COG0730	response to heat
IX92_RS12250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IX92_RS12255	COG0505	Belongs to the CarA family
IX92_RS12265	COG0494	nUDIX hydrolase
IX92_RS12275	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IX92_RS12280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IX92_RS12285	COG0849	cell division
IX92_RS12290	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IX92_RS12305	COG0772	Belongs to the SEDS family
IX92_RS12310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IX92_RS12320	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IX92_RS12325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IX92_RS12330	COG0768	penicillin binding
IX92_RS12335	COG3116	cell division
IX92_RS12345	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IX92_RS12350	COG3107	peptidoglycan biosynthetic process
IX92_RS12360	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IX92_RS12370	COG2969	positive regulation of protein catabolic process
IX92_RS12375	COG0625	glutathione transferase activity
IX92_RS12380	COG2857	Cytochrome c1
IX92_RS12385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IX92_RS12390	COG0723	plastoquinol--plastocyanin reductase activity
IX92_RS12405	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IX92_RS12410	COG3105	Protein conserved in bacteria
IX92_RS12415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IX92_RS12420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IX92_RS12435	COG3150	esterase
IX92_RS12445	COG3151	Protein conserved in bacteria
IX92_RS12450	COG0494	nUDIX hydrolase
IX92_RS12455	COG1538	Outer membrane efflux protein
IX92_RS12465	COG2198	Histidine kinase
IX92_RS12465	COG5002	protein histidine kinase activity
IX92_RS12465	COG0784	Response regulator, receiver
IX92_RS12470	COG2203	Gaf domain
IX92_RS12470	COG4251	negative regulation of phosphorylation
IX92_RS12470	COG5001	Diguanylate cyclase
IX92_RS12470	COG3706	GGDEF domain
IX92_RS12475	COG1242	4 iron, 4 sulfur cluster binding
IX92_RS12480	COG0069	glutamate synthase activity
IX92_RS12480	COG0070	glutamate synthase
IX92_RS12480	COG0067	glutamate synthase
IX92_RS12490	COG0067	glutamate synthase
IX92_RS12490	COG0069	glutamate synthase activity
IX92_RS12490	COG0070	glutamate synthase
IX92_RS12495	COG0493	'glutamate synthase
IX92_RS12520	COG0195	Participates in both transcription termination and antitermination
IX92_RS12525	COG0779	Required for maturation of 30S ribosomal subunits
IX92_RS12540	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IX92_RS12545	COG3153	acetyltransferase
IX92_RS12550	COG3154	lipid carrier protein
IX92_RS12560	COG0826	peptidase U32
IX92_RS12565	COG0826	peptidase U32
IX92_RS12570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IX92_RS12575	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IX92_RS12590	COG0513	Belongs to the DEAD box helicase family
IX92_RS12615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IX92_RS12620	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IX92_RS12625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IX92_RS12630	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IX92_RS12635	COG1534	Rna-binding protein
IX92_RS12640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IX92_RS12645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IX92_RS12650	COG2027	D-alanyl-D-alanine carboxypeptidase
IX92_RS12660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IX92_RS12665	COG0739	heme binding
IX92_RS12680	COG0316	Belongs to the HesB IscA family
IX92_RS12690	COG0628	permease
IX92_RS12695	COG2813	Specifically methylates the guanine in position
IX92_RS12700	COG2205	protein histidine kinase activity
IX92_RS12700	COG0784	Response regulator, receiver
IX92_RS12705	COG0747	negative chemotaxis
IX92_RS12720	COG0444	Belongs to the ABC transporter superfamily
IX92_RS12725	COG4608	Belongs to the ABC transporter superfamily
IX92_RS12735	COG2971	BadF BadG BcrA BcrD
IX92_RS12750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IX92_RS12755	COG3842	ATPase activity
IX92_RS12765	COG1840	ABC-type Fe3 transport system, periplasmic component
IX92_RS12770	COG0004	ammonium transporteR
IX92_RS12785	COG1049	propionate catabolic process, 2-methylcitrate cycle
IX92_RS12790	COG1752	Esterase of the alpha-beta hydrolase superfamily
IX92_RS12795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IX92_RS12800	COG1643	Atp-dependent helicase
IX92_RS12810	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IX92_RS12825	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IX92_RS12830	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IX92_RS12840	COG0842	Transport permease protein
IX92_RS12845	COG1131	(ABC) transporter
IX92_RS12850	COG0659	secondary active sulfate transmembrane transporter activity
IX92_RS12855	COG0288	reversible hydration of carbon dioxide
IX92_RS12870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IX92_RS12875	COG0508	dehydrogenase complex catalyzes the overall conversion of
IX92_RS12880	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IX92_RS12885	COG2186	Transcriptional regulator
IX92_RS12895	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IX92_RS12900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IX92_RS12905	COG4974	Belongs to the 'phage' integrase family
IX92_RS12915	COG3023	N-Acetylmuramoyl-L-alanine amidase
IX92_RS12920	COG0157	Belongs to the NadC ModD family
IX92_RS12925	COG4969	Belongs to the N-Me-Phe pilin family
IX92_RS12930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IX92_RS12935	COG1459	type II secretion system
IX92_RS12945	COG0237	dephospho-CoA kinase activity
IX92_RS12950	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IX92_RS12955	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IX92_RS12965	COG0336	Belongs to the RNA methyltransferase TrmD family
IX92_RS12975	COG0228	four-way junction DNA binding
IX92_RS12980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IX92_RS12985	COG4137	Cytochrome C assembly protein
IX92_RS12990	COG4536	flavin adenine dinucleotide binding
IX92_RS12995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IX92_RS13010	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IX92_RS13015	COG0585	pseudouridine synthase activity
IX92_RS13025	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IX92_RS13030	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IX92_RS13035	COG1968	undecaprenyl-diphosphatase activity
IX92_RS13040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IX92_RS13045	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IX92_RS13050	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IX92_RS13055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IX92_RS13060	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IX92_RS13065	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IX92_RS13070	COG1610	YqeY-like protein
IX92_RS13075	COG0358	DNA primase activity
IX92_RS13090	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IX92_RS13095	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IX92_RS13100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IX92_RS13110	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IX92_RS13120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IX92_RS13130	COG3610	response to peptide
IX92_RS13135	COG2966	Psort location CytoplasmicMembrane, score
IX92_RS13140	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IX92_RS13150	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IX92_RS13155	COG0142	geranyltranstransferase activity
IX92_RS13165	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IX92_RS13170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX92_RS13170	COG2213	PTS system mannitol-specific
IX92_RS13180	COG3722	fumarate hydratase activity
IX92_RS13185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IX92_RS13190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IX92_RS13195	COG1349	DNA-binding transcription factor activity
IX92_RS13200	COG0469	pyruvate kinase activity
IX92_RS13220	COG0583	DNA-binding transcription factor activity
IX92_RS13230	COG0442	prolyl-tRNA aminoacylation
IX92_RS13235	COG0668	transmembrane transport
IX92_RS13240	COG0191	fructose-bisphosphate aldolase activity
IX92_RS13250	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IX92_RS13255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IX92_RS13260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IX92_RS13270	COG3091	SprT-like family
IX92_RS13275	COG2356	endonuclease I
IX92_RS13280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IX92_RS13285	COG0189	ligase activity
IX92_RS13290	COG1678	Uncharacterized ACR, COG1678
IX92_RS13295	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IX92_RS13310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IX92_RS13315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IX92_RS13320	COG0762	integral membrane protein
IX92_RS13335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IX92_RS13340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IX92_RS13345	COG2066	Belongs to the glutaminase family
IX92_RS13350	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IX92_RS13360	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IX92_RS13415	COG0312	modulator of DNA gyrase
IX92_RS13420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IX92_RS13425	COG3164	Protein of unknown function
IX92_RS13435	COG0424	maF-like protein
IX92_RS13440	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IX92_RS13445	COG1792	Involved in formation and maintenance of cell shape
IX92_RS13450	COG1077	Cell shape determining protein MreB Mrl
IX92_RS13480	COG2165	general secretion pathway protein
IX92_RS13485	COG2165	general secretion pathway protein
IX92_RS13495	COG1459	type II secretion system
IX92_RS13500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IX92_RS13510	COG3267	Type II secretory pathway component ExeA
IX92_RS13510	COG3409	Peptidoglycan-binding domain 1 protein
IX92_RS13535	COG2199	diguanylate cyclase activity
IX92_RS13535	COG2200	EAL domain
IX92_RS13540	COG0629	single-stranded DNA binding
IX92_RS13555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IX92_RS13565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IX92_RS13570	COG0527	aspartate kinase activity
IX92_RS13575	COG0312	modulator of DNA gyrase
IX92_RS13580	COG3028	Belongs to the UPF0307 family
IX92_RS13585	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IX92_RS13590	COG1178	ABC-type Fe3 transport system permease component
IX92_RS13595	COG4143	(ABC) transporter
IX92_RS13600	COG0163	prenyltransferase activity
IX92_RS13605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IX92_RS13615	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IX92_RS13620	COG2105	PFAM AIG2 family protein
IX92_RS13630	COG0729	surface antigen
IX92_RS13635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IX92_RS13645	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IX92_RS13660	COG1136	(ABC) transporter
IX92_RS13685	COG0432	Pfam Uncharacterised protein family UPF0047
IX92_RS13690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IX92_RS13695	COG0305	Participates in initiation and elongation during chromosome replication
IX92_RS13715	COG0360	Binds together with S18 to 16S ribosomal RNA
IX92_RS13725	COG2906	2 iron, 2 sulfur cluster binding
IX92_RS13730	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IX92_RS13735	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IX92_RS13740	COG0049	tRNA binding
IX92_RS13750	COG2168	tRNA wobble position uridine thiolation
IX92_RS13755	COG2923	Belongs to the DsrF TusC family
IX92_RS13765	COG2964	Protein conserved in bacteria
IX92_RS13770	COG0545	Peptidyl-prolyl cis-trans isomerase
IX92_RS13780	COG2900	Belongs to the SlyX family
IX92_RS13785	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IX92_RS13790	COG0330	HflC and HflK could
IX92_RS13795	COG0330	HflC and HflK could
IX92_RS13800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IX92_RS13815	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IX92_RS13825	COG0802	atpase or kinase
IX92_RS13830	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IX92_RS13885	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IX92_RS13890	COG1162	GTPase activity
IX92_RS13895	COG0688	phosphatidylethanolamine metabolic process
IX92_RS13900	COG0490	domain, Protein
IX92_RS13900	COG0471	metal ion transport
IX92_RS13905	COG0840	transmembrane signaling receptor activity
IX92_RS13915	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IX92_RS13920	COG4942	peptidase
IX92_RS13940	COG2816	NAD+ diphosphatase activity
IX92_RS13945	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
IX92_RS13965	COG0085	RNA polymerase activity
IX92_RS13975	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IX92_RS13990	COG0250	Participates in transcription elongation, termination and antitermination
IX92_RS13995	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IX92_RS14005	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IX92_RS14030	COG1072	(Pantothenic acid kinase))
IX92_RS14045	COG0149	triose-phosphate isomerase activity
IX92_RS14050	COG0534	Mate efflux family protein
IX92_RS14055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IX92_RS14060	COG1575	Belongs to the MenA family. Type 1 subfamily
IX92_RS14065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IX92_RS14070	COG1509	lysine 2,3-aminomutase activity
IX92_RS14080	COG1285	pathogenesis
IX92_RS14085	COG0205	6-phosphofructokinase activity
IX92_RS14090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IX92_RS14095	COG3678	ATP-independent chaperone mediated protein folding
IX92_RS14100	COG0745	RESPONSE REGULATOR receiver
IX92_RS14105	COG2205	protein histidine kinase activity
IX92_RS14110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IX92_RS14115	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IX92_RS14120	COG0180	Tryptophanyl-tRNA synthetase
IX92_RS14125	COG0546	phosphoglycolate phosphatase activity
IX92_RS14130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IX92_RS14135	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IX92_RS14145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IX92_RS14180	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IX92_RS14190	COG0678	peroxiredoxin activity
IX92_RS14190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IX92_RS14200	COG0251	oxidation-reduction process
IX92_RS14205	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IX92_RS14205	COG0165	Argininosuccinate lyase
IX92_RS14210	COG0137	argininosuccinate synthase activity
IX92_RS14220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IX92_RS14310	COG0175	sulfate reduction
IX92_RS14315	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX92_RS14320	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IX92_RS14465	COG3437	response regulator, receiver
IX92_RS14475	COG0735	belongs to the Fur family
IX92_RS14485	COG0529	Catalyzes the synthesis of activated sulfate
IX92_RS14490	COG0471	metal ion transport
IX92_RS14490	COG3273	potassium ion transport
IX92_RS14505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IX92_RS14505	COG1648	precorrin-2 dehydrogenase activity
IX92_RS14510	COG0737	Belongs to the 5'-nucleotidase family
IX92_RS14520	COG2153	protein acetylation
IX92_RS14535	COG0545	Peptidyl-prolyl cis-trans isomerase
IX92_RS14545	COG0203	ribosomal protein L17
IX92_RS14550	COG0202	RNA polymerase activity
IX92_RS14560	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IX92_RS14565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IX92_RS14570	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IX92_RS14575	COG0201	protein transport
IX92_RS14580	COG0200	Binds to the 23S rRNA
IX92_RS14585	COG1841	ribosomal large subunit assembly
IX92_RS14600	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IX92_RS14615	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IX92_RS14630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IX92_RS14645	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IX92_RS14650	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IX92_RS14655	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IX92_RS14670	COG0088	Forms part of the polypeptide exit tunnel
IX92_RS14675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IX92_RS14680	COG0051	transcription antitermination factor activity, RNA binding
IX92_RS14685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IX92_RS14690	COG0557	exoribonuclease II activity
IX92_RS14695	COG0402	S-adenosylhomocysteine deaminase activity
IX92_RS14700	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IX92_RS14705	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IX92_RS14715	COG1047	Peptidyl-prolyl cis-trans
IX92_RS14730	COG2249	NAD(P)H dehydrogenase (quinone) activity
IX92_RS14735	COG0488	(ABC) transporter
IX92_RS14745	COG0429	hydrolase of the alpha beta-hydrolase fold
IX92_RS14750	COG3089	Belongs to the UPF0270 family
IX92_RS14755	COG3954	Phosphoribulokinase
IX92_RS14760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IX92_RS14770	COG1012	belongs to the aldehyde dehydrogenase family
IX92_RS14780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IX92_RS14810	COG3210	domain, Protein
IX92_RS14815	COG3210	domain, Protein
IX92_RS14835	COG1027	Aspartate ammonia-lyase
IX92_RS14840	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IX92_RS14845	COG1288	antiporter activity
IX92_RS14860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IX92_RS14865	COG0540	Belongs to the ATCase OTCase family
IX92_RS14870	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IX92_RS14875	COG1438	arginine binding
IX92_RS14880	COG4232	protein-disulfide reductase activity
IX92_RS14890	COG2095	MarC family integral membrane protein
IX92_RS14900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IX92_RS14910	COG0784	Response regulator, receiver
IX92_RS14910	COG2205	protein histidine kinase activity
IX92_RS14915	COG2814	Major facilitator Superfamily
IX92_RS14930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IX92_RS14935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IX92_RS14940	COG0511	ligase activity, forming carbon-carbon bonds
IX92_RS14945	COG0439	Biotin carboxylase
IX92_RS14950	COG2264	protein methyltransferase activity
IX92_RS14955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IX92_RS14960	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IX92_RS14965	COG2199	diguanylate cyclase activity
IX92_RS14970	COG0789	Transcriptional regulator
IX92_RS14975	COG0138	bifunctional purine biosynthesis protein purh
IX92_RS14980	COG0151	Belongs to the GarS family
IX92_RS14995	COG1253	flavin adenine dinucleotide binding
IX92_RS15005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IX92_RS15010	COG1573	uracil-dna glycosylase
IX92_RS15015	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IX92_RS15020	COG1695	Transcriptional regulator
IX92_RS15025	COG1045	serine acetyltransferase
IX92_RS15040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IX92_RS15045	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IX92_RS15050	COG1053	succinate dehydrogenase
IX92_RS15055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IX92_RS15080	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IX92_RS15085	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IX92_RS15090	COG1609	Transcriptional regulator
IX92_RS15095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IX92_RS15105	COG0281	malic enzyme
IX92_RS15110	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
IX92_RS15115	COG0626	cystathionine gamma-synthase activity
IX92_RS15120	COG0527	aspartate kinase activity
IX92_RS15120	COG0460	homoserine dehydrogenase
IX92_RS15125	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IX92_RS15130	COG3074	FtsZ-dependent cytokinesis
IX92_RS15135	COG1494	fructose-1,6-bisphosphatase
IX92_RS15160	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IX92_RS15165	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IX92_RS15165	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IX92_RS15170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IX92_RS15180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IX92_RS15185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IX92_RS15195	COG2076	Multidrug Resistance protein
IX92_RS15205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IX92_RS15210	COG1028	Short-chain dehydrogenase reductase Sdr
IX92_RS15240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IX92_RS15255	COG0438	transferase activity, transferring glycosyl groups
IX92_RS15260	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IX92_RS15260	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IX92_RS15265	COG0367	asparagine synthase
IX92_RS15275	COG0438	transferase activity, transferring glycosyl groups
IX92_RS15300	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IX92_RS15320	COG0859	PFAM glycosyl transferase family 9
IX92_RS15335	COG1519	Transferase
IX92_RS15360	COG3642	lipopolysaccharide core region biosynthetic process
IX92_RS15365	COG0859	PFAM glycosyl transferase family 9
IX92_RS15370	COG0463	Glycosyl transferase, family 2
IX92_RS15375	COG0859	PFAM glycosyl transferase family 9
IX92_RS15380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IX92_RS15400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IX92_RS15405	COG2003	Belongs to the UPF0758 family
IX92_RS15410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IX92_RS15415	COG1309	transcriptional regulator
IX92_RS15420	COG1560	Kdo2-lipid A biosynthetic process
IX92_RS15425	COG1560	Kdo2-lipid A biosynthetic process
IX92_RS15430	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IX92_RS15435	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IX92_RS15440	COG1561	YicC-like family, N-terminal region
IX92_RS15445	COG2252	PERMEase
IX92_RS15455	COG0848	biopolymer transport protein
IX92_RS15485	COG1595	DNA-templated transcription, initiation
IX92_RS15490	COG0194	GDP metabolic process
IX92_RS15495	COG1758	RNA polymerase activity
IX92_RS15500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IX92_RS15505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IX92_RS15510	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IX92_RS15515	COG1218	3'(2'),5'-bisphosphate nucleotidase
IX92_RS15520	COG0494	nUDIX hydrolase
IX92_RS15525	COG0316	Belongs to the HesB IscA family
IX92_RS15525	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IX92_RS15535	COG0596	Alpha beta hydrolase
IX92_RS15545	COG2183	response to ionizing radiation
IX92_RS15555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IX92_RS15575	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IX92_RS15580	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IX92_RS15585	COG3156	type II secretion system protein K
IX92_RS15590	COG4795	General secretion pathway protein
IX92_RS15595	COG2165	general secretion pathway protein
IX92_RS15600	COG2165	general secretion pathway protein
IX92_RS15605	COG2165	general secretion pathway protein
IX92_RS15610	COG1459	type II secretion system
IX92_RS15615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IX92_RS15625	COG3031	protein transport across the cell outer membrane
IX92_RS15630	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IX92_RS15640	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IX92_RS15650	COG0456	acetyltransferase
IX92_RS15655	COG1490	D-aminoacyl-tRNA deacylase activity
IX92_RS15660	COG1295	ribonuclease BN
IX92_RS15670	COG1217	gtp-binding protein TYPA
IX92_RS15675	COG0174	glutamine synthetase
IX92_RS15680	COG3852	Histidine kinase
IX92_RS15685	COG2204	response regulator
IX92_RS15695	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IX92_RS15735	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IX92_RS15750	COG0408	coproporphyrinogen oxidase activity
IX92_RS15760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IX92_RS15765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IX92_RS15770	COG0551	DNA topoisomerase type I activity
IX92_RS15775	COG2922	Belongs to the Smg family
IX92_RS15780	COG0758	DNA mediated transformation
IX92_RS15795	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IX92_RS15795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IX92_RS15800	COG0569	domain protein
IX92_RS15805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IX92_RS15815	COG1272	protein, Hemolysin III
IX92_RS15820	COG4326	sporulation control protein
IX92_RS15830	COG3084	Protein conserved in bacteria
IX92_RS15840	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IX92_RS15845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IX92_RS15850	COG0204	Acyl-transferase
IX92_RS15860	COG0606	chelatase, subunit chli
IX92_RS15870	COG3978	acetolactate synthase activity
IX92_RS15875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IX92_RS15880	COG0129	dihydroxy-acid dehydratase activity
IX92_RS15890	COG0604	alcohol dehydrogenase
IX92_RS15905	COG0425	Belongs to the sulfur carrier protein TusA family
IX92_RS15915	COG2119	membrane
IX92_RS15920	COG0752	glycyl-tRNA synthetase alpha subunit
IX92_RS15925	COG0751	glycine-tRNA ligase activity
IX92_RS15930	COG3977	Valine--pyruvate aminotransferase
IX92_RS15935	COG0071	Belongs to the small heat shock protein (HSP20) family
IX92_RS15940	COG0187	DNA topoisomerase II activity
IX92_RS15945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IX92_RS15950	COG0592	DNA-directed DNA polymerase activity
IX92_RS15970	COG1126	abc transporter atp-binding protein
IX92_RS15975	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IX92_RS15985	COG0706	membrane insertase activity
IX92_RS15990	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IX92_RS15995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IX92_RS16230	COG5002	protein histidine kinase activity
IX92_RS16230	COG5001	Diguanylate cyclase
IX92_RS16230	COG3447	MASE1 domain protein
IX92_RS16365	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IX92_RS16365	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IX92_RS16610	COG0248	Ppx GppA phosphatase
IX92_RS16690	COG3072	Adenylate cyclase
IX92_RS16725	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IX92_RS16940	COG4206	TonB-dependent receptor
IX92_RS17030	COG0646	methionine synthase
IX92_RS17030	COG1410	methionine synthase
IX92_RS17085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IX92_RS17920	COG0534	Mate efflux family protein
IX92_RS17930	COG2204	response regulator
IX92_RS17940	COG0667	Aldo Keto reductase
IX92_RS17990	COG0728	peptidoglycan biosynthetic process
IX92_RS18180	COG0483	inositol monophosphate 1-phosphatase activity
IX92_RS18340	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IX92_RS18340	COG3408	Glycogen debranching enzyme
IX92_RS18380	COG3250	beta-galactosidase activity
IX92_RS18715	COG1160	GTP binding
IX92_RS18910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IX92_RS19095	COG0047	phosphoribosylformylglycinamidine synthase activity
IX92_RS19095	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IX92_RS19110	COG0047	phosphoribosylformylglycinamidine synthase activity
IX92_RS19110	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IX92_RS19600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IX92_RS19765	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IX92_RS19810	COG2067	long-chain fatty acid transport protein
IX92_RS19935	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IX92_RS20170	COG0659	secondary active sulfate transmembrane transporter activity
IX92_RS20230	COG1399	metal-binding, possibly nucleic acid-binding protein
IX92_RS20295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IX92_RS20295	COG1263	PTS System
IX92_RS20345	COG1940	carbohydrate kinase activity
IX92_RS20460	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IX92_RS20500	COG0318	PFAM AMP-dependent synthetase and ligase
IX92_RS20655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IX92_RS21000	COG1674	ftsk spoiiie
IX92_RS21115	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IX92_RS21130	COG2719	SpoVR family
IX92_RS21510	COG1643	Atp-dependent helicase
IX92_RS22130	COG2824	Alkylphosphonate utilization operon protein PhnA
IX92_RS22655	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IX92_RS23000	COG3008	intermembrane lipid transfer
IX92_RS23005	COG3008	intermembrane lipid transfer
IX92_RS23880	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IX92_RS23880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IX92_RS24055	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IX92_RS24070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX92_RS24080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX92_RS24090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX92_RS24220	COG1328	CTP reductase activity
IX92_RS24370	COG0577	efflux transmembrane transporter activity
IX92_RS25120	COG0006	proline dipeptidase activity
IX92_RS25380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IX92_RS25380	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IX92_RS25385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IX92_RS25385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IX92_RS25465	COG0583	DNA-binding transcription factor activity
IX92_RS25490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX92_RS25695	COG0248	Ppx GppA phosphatase
IX92_RS25880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IX92_RS25965	COG2177	Part of the ABC transporter FtsEX involved in
IX92_RS26000	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IX92_RS26160	COG0646	methionine synthase
IX92_RS26160	COG1410	methionine synthase
IX92_RS26325	COG0039	L-malate dehydrogenase activity
IX92_RS26360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IX92_RS26390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IX92_RS26485	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IX92_RS26505	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IX92_RS26510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IX92_RS27090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IX92_RS27120	COG0148	phosphopyruvate hydratase activity
IX92_RS27395	COG2081	HI0933 family
IX92_RS27570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX92_RS27580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX92_RS27765	COG0405	Gamma-glutamyltransferase
IX92_RS27910	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IX92_RS28100	COG1410	methionine synthase
IX92_RS28100	COG0646	methionine synthase
IX92_RS28305	COG0525	valine-tRNA ligase activity
IX92_RS28410	COG2918	glutathione biosynthetic process
IX92_RS28615	COG3710	Transcriptional regulator