locus-tag	class	description
OCW38_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OCW38_RS00010	COG0592	DNA-directed DNA polymerase activity
OCW38_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OCW38_RS00020	COG0187	DNA topoisomerase II activity
OCW38_RS00025	COG3344	reverse transcriptase
OCW38_RS00030	COG3344	reverse transcriptase
OCW38_RS00035	COG0071	Belongs to the small heat shock protein (HSP20) family
OCW38_RS00040	COG3977	Valine--pyruvate aminotransferase
OCW38_RS00045	COG0366	Alpha amylase catalytic
OCW38_RS00050	COG0751	glycine-tRNA ligase activity
OCW38_RS00055	COG0752	glycyl-tRNA synthetase alpha subunit
OCW38_RS00060	COG2119	membrane
OCW38_RS00070	COG0425	Belongs to the sulfur carrier protein TusA family
OCW38_RS00085	COG0604	alcohol dehydrogenase
OCW38_RS00090	COG0183	Belongs to the thiolase family
OCW38_RS00095	COG1250	3-hydroxyacyl-CoA dehydrogenase
OCW38_RS00095	COG1024	Enoyl-CoA hydratase
OCW38_RS00100	COG1739	Uncharacterized protein family UPF0029
OCW38_RS00105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OCW38_RS00110	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
OCW38_RS00155	COG2132	Multicopper oxidase
OCW38_RS00165	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OCW38_RS00170	COG0352	thiamine-phosphate diphosphorylase activity
OCW38_RS00175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OCW38_RS00180	COG2104	thiamine diphosphate biosynthetic process
OCW38_RS00185	COG2022	thiamine diphosphate biosynthetic process
OCW38_RS00195	COG0006	proline dipeptidase activity
OCW38_RS00195	COG0006	proline dipeptidase activity
OCW38_RS00205	COG2814	Major facilitator Superfamily
OCW38_RS00225	COG3220	belongs to the UPF0276 family
OCW38_RS00235	COG0210	DNA helicase
OCW38_RS00245	COG0405	Gamma-glutamyltransferase
OCW38_RS00250	COG1280	lysine exporter protein (LysE YggA)
OCW38_RS00260	COG2962	Rard protein
OCW38_RS00265	COG0514	ATP-dependent DNA helicase (RecQ)
OCW38_RS00275	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OCW38_RS00280	COG0248	Ppx GppA phosphatase
OCW38_RS00285	COG0513	Belongs to the DEAD box helicase family
OCW38_RS00290	COG3118	belongs to the thioredoxin family
OCW38_RS00305	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OCW38_RS00365	COG3071	HemY protein
OCW38_RS00370	COG2959	enzyme of heme biosynthesis
OCW38_RS00375	COG1587	Uroporphyrinogen-III synthase
OCW38_RS00380	COG0181	hydroxymethylbilane synthase activity
OCW38_RS00385	COG3072	Adenylate cyclase
OCW38_RS00390	COG1965	Belongs to the frataxin family
OCW38_RS00400	COG0019	diaminopimelate decarboxylase activity
OCW38_RS00405	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OCW38_RS00415	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OCW38_RS00420	COG1011	Hydrolase
OCW38_RS00425	COG2199	diguanylate cyclase activity
OCW38_RS00425	COG2200	EAL domain
OCW38_RS00425	COG3287	FIST C domain
OCW38_RS00430	COG2199	diguanylate cyclase activity
OCW38_RS00430	COG2200	EAL domain
OCW38_RS00430	COG3287	FIST C domain
OCW38_RS00435	COG3148	PFAM DTW domain containing protein
OCW38_RS00450	COG3385	transposase activity
OCW38_RS00455	COG0561	phosphatase activity
OCW38_RS00460	COG2267	carboxylic ester hydrolase activity
OCW38_RS00465	COG1280	lysine exporter protein (LysE YggA)
OCW38_RS00470	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OCW38_RS00475	COG0640	Transcriptional regulator
OCW38_RS00480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OCW38_RS00520	COG2095	MarC family integral membrane protein
OCW38_RS00530	COG0742	ribosomal rna small subunit methyltransferase
OCW38_RS00535	COG0552	protein localization to endoplasmic reticulum
OCW38_RS00540	COG2884	Cell division ATP-binding protein ftsE
OCW38_RS00545	COG2177	Part of the ABC transporter FtsEX involved in
OCW38_RS00555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OCW38_RS00560	COG0705	Rhomboid family
OCW38_RS00565	COG1580	Controls the rotational direction of flagella during chemotaxis
OCW38_RS00570	COG3161	chorismate lyase activity
OCW38_RS00575	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OCW38_RS00585	COG2937	Belongs to the GPAT DAPAT family
OCW38_RS00590	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OCW38_RS00595	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OCW38_RS00600	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OCW38_RS00605	COG0534	Mate efflux family protein
OCW38_RS00610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCW38_RS00625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OCW38_RS00630	COG4206	TonB-dependent receptor
OCW38_RS00640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OCW38_RS00725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OCW38_RS00735	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OCW38_RS00745	COG1072	(Pantothenic acid kinase))
OCW38_RS00770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OCW38_RS00775	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OCW38_RS00780	COG0250	Participates in transcription elongation, termination and antitermination
OCW38_RS00790	COG0081	regulation of translation
OCW38_RS00795	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OCW38_RS00800	COG0222	ribosome binding
OCW38_RS00815	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
OCW38_RS00820	COG2816	NAD+ diphosphatase activity
OCW38_RS00830	COG1573	uracil-dna glycosylase
OCW38_RS00840	COG3068	Protein conserved in bacteria
OCW38_RS00845	COG1253	flavin adenine dinucleotide binding
OCW38_RS00860	COG0151	Belongs to the GarS family
OCW38_RS00865	COG0138	bifunctional purine biosynthesis protein purh
OCW38_RS00870	COG0789	Transcriptional regulator
OCW38_RS00875	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OCW38_RS00880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OCW38_RS00885	COG2264	protein methyltransferase activity
OCW38_RS00890	COG0439	Biotin carboxylase
OCW38_RS00895	COG0511	ligase activity, forming carbon-carbon bonds
OCW38_RS00900	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OCW38_RS00905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OCW38_RS00920	COG2814	Major facilitator Superfamily
OCW38_RS00925	COG2198	Histidine kinase
OCW38_RS00925	COG2205	protein histidine kinase activity
OCW38_RS00925	COG0784	Response regulator, receiver
OCW38_RS00940	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCW38_RS00950	COG3263	regulation of cellular component size
OCW38_RS00960	COG4232	protein-disulfide reductase activity
OCW38_RS00965	COG1438	arginine binding
OCW38_RS00970	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
OCW38_RS00975	COG0540	Belongs to the ATCase OTCase family
OCW38_RS00985	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OCW38_RS00990	COG0549	Belongs to the carbamate kinase family
OCW38_RS01000	COG1288	antiporter activity
OCW38_RS01005	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
OCW38_RS01010	COG1027	Aspartate ammonia-lyase
OCW38_RS01020	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OCW38_RS01030	COG2205	protein histidine kinase activity
OCW38_RS01035	COG0745	RESPONSE REGULATOR receiver
OCW38_RS01045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OCW38_RS01055	COG0149	triose-phosphate isomerase activity
OCW38_RS01065	COG3152	Membrane
OCW38_RS01070	COG3547	Transposase (IS116 IS110 IS902 family)
OCW38_RS01075	COG3344	reverse transcriptase
OCW38_RS01100	COG1494	fructose-1,6-bisphosphatase
OCW38_RS01105	COG3074	FtsZ-dependent cytokinesis
OCW38_RS01110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OCW38_RS01115	COG1575	Belongs to the MenA family. Type 1 subfamily
OCW38_RS01120	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OCW38_RS01125	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OCW38_RS01135	COG1609	Transcriptional regulator
OCW38_RS01140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OCW38_RS01145	COG0254	rRNA binding
OCW38_RS01150	COG0281	malic enzyme
OCW38_RS01155	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
OCW38_RS01160	COG0626	cystathionine gamma-synthase activity
OCW38_RS01165	COG0460	homoserine dehydrogenase
OCW38_RS01165	COG0527	aspartate kinase activity
OCW38_RS01170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OCW38_RS01180	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OCW38_RS01185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OCW38_RS01190	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OCW38_RS01205	COG0165	Argininosuccinate lyase
OCW38_RS01205	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OCW38_RS01215	COG0251	oxidation-reduction process
OCW38_RS01220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCW38_RS01225	COG0678	peroxiredoxin activity
OCW38_RS01225	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OCW38_RS01235	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OCW38_RS01270	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OCW38_RS01280	COG0338	D12 class N6 adenine-specific DNA methyltransferase
OCW38_RS01285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OCW38_RS01295	COG0180	Tryptophanyl-tRNA synthetase
OCW38_RS01305	COG0512	Glutamine amidotransferase of anthranilate synthase
OCW38_RS01310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OCW38_RS01320	COG1012	belongs to the aldehyde dehydrogenase family
OCW38_RS01330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OCW38_RS01335	COG3954	Phosphoribulokinase
OCW38_RS01340	COG3089	Belongs to the UPF0270 family
OCW38_RS01345	COG0429	hydrolase of the alpha beta-hydrolase fold
OCW38_RS01355	COG0488	(ABC) transporter
OCW38_RS01360	COG2249	NAD(P)H dehydrogenase (quinone) activity
OCW38_RS01375	COG1047	Peptidyl-prolyl cis-trans
OCW38_RS01380	COG1446	asparaginase
OCW38_RS01385	COG2900	Belongs to the SlyX family
OCW38_RS01395	COG0545	Peptidyl-prolyl cis-trans isomerase
OCW38_RS01400	COG2964	Protein conserved in bacteria
OCW38_RS01405	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OCW38_RS01410	COG2923	Belongs to the DsrF TusC family
OCW38_RS01430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OCW38_RS01435	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OCW38_RS01440	COG3547	Transposase (IS116 IS110 IS902 family)
OCW38_RS01445	COG3344	reverse transcriptase
OCW38_RS01455	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OCW38_RS01460	COG0088	Forms part of the polypeptide exit tunnel
OCW38_RS01465	COG0089	rRNA binding
OCW38_RS01470	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OCW38_RS01475	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OCW38_RS01485	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OCW38_RS01490	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OCW38_RS01500	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OCW38_RS01505	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OCW38_RS01510	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OCW38_RS01515	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OCW38_RS01520	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OCW38_RS01525	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OCW38_RS01530	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OCW38_RS01535	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OCW38_RS01540	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OCW38_RS01545	COG1841	ribosomal large subunit assembly
OCW38_RS01550	COG0200	Binds to the 23S rRNA
OCW38_RS01555	COG0201	protein transport
OCW38_RS01560	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OCW38_RS01565	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OCW38_RS01570	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OCW38_RS01575	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OCW38_RS01580	COG0202	RNA polymerase activity
OCW38_RS01585	COG0203	ribosomal protein L17
OCW38_RS01595	COG0545	Peptidyl-prolyl cis-trans isomerase
OCW38_RS01600	COG3061	Opacity-associated protein A
OCW38_RS01600	COG3266	domain, Protein
OCW38_RS01610	COG2153	protein acetylation
OCW38_RS01655	COG0737	Belongs to the 5'-nucleotidase family
OCW38_RS01660	COG0175	sulfate reduction
OCW38_RS01665	COG2895	sulfate adenylyltransferase (ATP) activity
OCW38_RS01670	COG3273	potassium ion transport
OCW38_RS01670	COG0471	metal ion transport
OCW38_RS01675	COG0529	Catalyzes the synthesis of activated sulfate
OCW38_RS01710	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
OCW38_RS01720	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCW38_RS01725	COG0729	surface antigen
OCW38_RS01730	COG2911	Protein conserved in bacteria
OCW38_RS01735	COG2105	PFAM AIG2 family protein
OCW38_RS01740	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
OCW38_RS01745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OCW38_RS01750	COG0163	prenyltransferase activity
OCW38_RS01755	COG4143	(ABC) transporter
OCW38_RS01760	COG1178	ABC-type Fe3 transport system permease component
OCW38_RS01765	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
OCW38_RS01770	COG3028	Belongs to the UPF0307 family
OCW38_RS01775	COG0312	modulator of DNA gyrase
OCW38_RS01780	COG2239	Acts as a magnesium transporter
OCW38_RS01785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCW38_RS01790	COG1660	Displays ATPase and GTPase activities
OCW38_RS01795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCW38_RS01800	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OCW38_RS01810	COG1137	ATPase activity
OCW38_RS01815	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OCW38_RS01825	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OCW38_RS01830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OCW38_RS01830	COG0517	IMP dehydrogenase activity
OCW38_RS01840	COG1127	ABC transporter
OCW38_RS01845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OCW38_RS01850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OCW38_RS01855	COG2854	intermembrane phospholipid transfer
OCW38_RS01865	COG5007	Belongs to the BolA IbaG family
OCW38_RS01870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OCW38_RS01875	COG0204	Acyl-transferase
OCW38_RS01880	COG0251	oxidation-reduction process
OCW38_RS01885	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
OCW38_RS01915	COG0456	acetyltransferase
OCW38_RS01925	COG0525	valine-tRNA ligase activity
OCW38_RS01930	COG2927	DNA polymerase III (CHI subunit)
OCW38_RS01935	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OCW38_RS01940	COG0795	lipopolysaccharide-transporting ATPase activity
OCW38_RS01945	COG0795	lipopolysaccharide-transporting ATPase activity
OCW38_RS02020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCW38_RS02020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCW38_RS02050	COG3344	reverse transcriptase
OCW38_RS02160	COG0840	transmembrane signaling receptor activity
OCW38_RS02200	COG0741	lytic transglycosylase activity
OCW38_RS02205	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
OCW38_RS02220	COG2066	Belongs to the glutaminase family
OCW38_RS02225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OCW38_RS02230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OCW38_RS02245	COG0762	integral membrane protein
OCW38_RS02250	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OCW38_RS02255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OCW38_RS02275	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OCW38_RS02280	COG1678	Uncharacterized ACR, COG1678
OCW38_RS02285	COG0189	ligase activity
OCW38_RS02290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OCW38_RS02295	COG2356	endonuclease I
OCW38_RS02300	COG3091	SprT-like family
OCW38_RS02310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OCW38_RS02315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OCW38_RS02330	COG0191	fructose-bisphosphate aldolase activity
OCW38_RS02335	COG0668	transmembrane transport
OCW38_RS02355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OCW38_RS02360	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OCW38_RS02365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OCW38_RS02375	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OCW38_RS02380	COG3079	Belongs to the UPF0149 family
OCW38_RS02385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OCW38_RS02390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OCW38_RS02405	COG0354	folic acid binding
OCW38_RS02410	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OCW38_RS02415	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OCW38_RS02420	COG1595	DNA-templated transcription, initiation
OCW38_RS02440	COG0481	GTPase activity
OCW38_RS02450	COG0571	ribonuclease III activity
OCW38_RS02455	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OCW38_RS02460	COG1381	Involved in DNA repair and RecF pathway recombination
OCW38_RS02465	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OCW38_RS02470	COG0736	holo-[acyl-carrier-protein] synthase activity
OCW38_RS02475	COG3437	response regulator, receiver
OCW38_RS02475	COG2205	protein histidine kinase activity
OCW38_RS02475	COG4999	Histidine kinase
OCW38_RS02475	COG3850	Histidine kinase
OCW38_RS02480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OCW38_RS02485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OCW38_RS02490	COG3956	TIGRFAM MazG family protein
OCW38_RS02495	COG0504	CTP synthase activity
OCW38_RS02500	COG0148	phosphopyruvate hydratase activity
OCW38_RS02505	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OCW38_RS02510	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OCW38_RS02520	COG0585	pseudouridine synthase activity
OCW38_RS02525	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OCW38_RS02530	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OCW38_RS02565	COG1546	Belongs to the CinA family
OCW38_RS02570	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OCW38_RS02580	COG0527	aspartate kinase activity
OCW38_RS02585	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OCW38_RS02640	COG3630	sodium ion export across plasma membrane
OCW38_RS02645	COG0511	ligase activity, forming carbon-carbon bonds
OCW38_RS02645	COG5016	pyruvate
OCW38_RS02650	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
OCW38_RS02660	COG1238	metal cluster binding
OCW38_RS02665	COG0612	Peptidase, M16
OCW38_RS02680	COG1854	S-ribosylhomocysteine lyase activity
OCW38_RS02685	COG4536	flavin adenine dinucleotide binding
OCW38_RS02690	COG4137	Cytochrome C assembly protein
OCW38_RS02695	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OCW38_RS02705	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OCW38_RS02710	COG0336	Belongs to the RNA methyltransferase TrmD family
OCW38_RS02715	COG0335	large ribosomal subunit rRNA binding
OCW38_RS02725	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
OCW38_RS02730	COG0237	dephospho-CoA kinase activity
OCW38_RS02740	COG1459	type II secretion system
OCW38_RS02745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OCW38_RS02750	COG4969	Belongs to the N-Me-Phe pilin family
OCW38_RS02755	COG0157	Belongs to the NadC ModD family
OCW38_RS02765	COG2186	Transcriptional regulator
OCW38_RS02770	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OCW38_RS02775	COG0508	dehydrogenase complex catalyzes the overall conversion of
OCW38_RS02780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCW38_RS02795	COG0288	reversible hydration of carbon dioxide
OCW38_RS02800	COG0659	secondary active sulfate transmembrane transporter activity
OCW38_RS02805	COG1131	(ABC) transporter
OCW38_RS02810	COG0842	Transport permease protein
OCW38_RS02815	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OCW38_RS02820	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OCW38_RS02825	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OCW38_RS02845	COG1489	DNA binding
OCW38_RS02850	COG1643	Atp-dependent helicase
OCW38_RS02855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OCW38_RS02860	COG1752	Esterase of the alpha-beta hydrolase superfamily
OCW38_RS02865	COG1049	propionate catabolic process, 2-methylcitrate cycle
OCW38_RS02880	COG0004	ammonium transporteR
OCW38_RS02885	COG1840	ABC-type Fe3 transport system, periplasmic component
OCW38_RS02895	COG3842	ATPase activity
OCW38_RS02900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OCW38_RS02915	COG2971	BadF BadG BcrA BcrD
OCW38_RS02925	COG4608	Belongs to the ABC transporter superfamily
OCW38_RS02930	COG0444	Belongs to the ABC transporter superfamily
OCW38_RS02935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCW38_RS02945	COG0747	negative chemotaxis
OCW38_RS02950	COG0784	Response regulator, receiver
OCW38_RS02950	COG2205	protein histidine kinase activity
OCW38_RS02955	COG2813	Specifically methylates the guanine in position
OCW38_RS02960	COG0628	permease
OCW38_RS02965	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OCW38_RS02970	COG0316	Belongs to the HesB IscA family
OCW38_RS02985	COG0739	heme binding
OCW38_RS02990	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OCW38_RS02995	COG2239	Acts as a magnesium transporter
OCW38_RS03000	COG2027	D-alanyl-D-alanine carboxypeptidase
OCW38_RS03005	COG3385	transposase activity
OCW38_RS03010	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
OCW38_RS03015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OCW38_RS03020	COG1534	Rna-binding protein
OCW38_RS03025	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OCW38_RS03030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OCW38_RS03035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OCW38_RS03040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OCW38_RS03045	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OCW38_RS03060	COG0779	Required for maturation of 30S ribosomal subunits
OCW38_RS03065	COG0195	Participates in both transcription termination and antitermination
OCW38_RS03070	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OCW38_RS03075	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OCW38_RS03080	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OCW38_RS03085	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OCW38_RS03090	COG1185	polyribonucleotide nucleotidyltransferase activity
OCW38_RS03105	COG0534	Mate efflux family protein
OCW38_RS03110	COG0826	peptidase U32
OCW38_RS03115	COG0826	peptidase U32
OCW38_RS03125	COG3154	lipid carrier protein
OCW38_RS03130	COG3153	acetyltransferase
OCW38_RS03145	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OCW38_RS03155	COG0084	hydrolase, TatD family'
OCW38_RS03160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OCW38_RS03165	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OCW38_RS03170	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OCW38_RS03180	COG0813	purine-nucleoside phosphorylase activity
OCW38_RS03190	COG0560	Phosphoserine phosphatase
OCW38_RS03200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OCW38_RS03205	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OCW38_RS03210	COG4628	conserved protein (DUF2132)
OCW38_RS03225	COG1022	Amp-dependent synthetase and ligase
OCW38_RS03235	COG2059	Chromate
OCW38_RS03240	COG0583	DNA-binding transcription factor activity
OCW38_RS03245	COG1609	Transcriptional regulator
OCW38_RS03255	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCW38_RS03260	COG0534	Mate efflux family protein
OCW38_RS03270	COG1175	transmembrane transport
OCW38_RS03275	COG0395	ABC-type sugar transport system, permease component
OCW38_RS03285	COG3250	beta-galactosidase activity
OCW38_RS03295	COG1609	Transcriptional regulator
OCW38_RS03300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OCW38_RS03305	COG1085	galactose-1-phosphate uridylyltransferase
OCW38_RS03315	COG2017	converts alpha-aldose to the beta-anomer
OCW38_RS03320	COG1609	Transcriptional regulator
OCW38_RS03340	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OCW38_RS03360	COG2195	Cleaves the N-terminal amino acid of tripeptides
OCW38_RS03365	COG2252	PERMEase
OCW38_RS03370	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
OCW38_RS03375	COG1073	alpha beta
OCW38_RS03390	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OCW38_RS03395	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OCW38_RS03400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OCW38_RS03400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OCW38_RS03420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OCW38_RS03425	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OCW38_RS03430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OCW38_RS03440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OCW38_RS03445	COG0142	geranyltranstransferase activity
OCW38_RS03450	COG1722	exodeoxyribonuclease VII activity
OCW38_RS03455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OCW38_RS03465	COG0301	tRNA thio-modification
OCW38_RS03465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OCW38_RS03470	COG0583	DNA-binding transcription factor activity
OCW38_RS03485	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
OCW38_RS03490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCW38_RS03495	COG1611	Belongs to the LOG family
OCW38_RS03510	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OCW38_RS03510	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OCW38_RS03520	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
OCW38_RS03525	COG4580	involved in the transport of maltose and maltodextrins
OCW38_RS03530	COG1464	Belongs to the NlpA lipoprotein family
OCW38_RS03535	COG2011	ABC-type metal ion transport system permease component
OCW38_RS03540	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OCW38_RS03545	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OCW38_RS03555	COG1609	Transcriptional regulator
OCW38_RS03560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCW38_RS03560	COG1263	PTS System
OCW38_RS03565	COG0366	Alpha amylase catalytic
OCW38_RS03570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OCW38_RS03575	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OCW38_RS03600	COG0442	prolyl-tRNA aminoacylation
OCW38_RS03605	COG1720	tRNA m6t6A37 methyltransferase activity
OCW38_RS03610	COG0254	rRNA binding
OCW38_RS03620	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OCW38_RS03630	COG1671	Belongs to the UPF0178 family
OCW38_RS03655	COG3098	single-species biofilm formation
OCW38_RS03660	COG0564	pseudouridine synthase activity
OCW38_RS03670	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
OCW38_RS03675	COG0024	Methionine aminopeptidase
OCW38_RS03680	COG0052	Belongs to the universal ribosomal protein uS2 family
OCW38_RS03685	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OCW38_RS03690	COG0528	UMP kinase activity
OCW38_RS03695	COG0233	cytoplasmic translational termination
OCW38_RS03700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OCW38_RS03705	COG0575	Belongs to the CDS family
OCW38_RS03715	COG0750	zinc metalloprotease
OCW38_RS03725	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
OCW38_RS03730	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCW38_RS03735	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OCW38_RS03740	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCW38_RS03750	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OCW38_RS03755	COG0587	DNA-directed DNA polymerase activity
OCW38_RS03760	COG0825	malonyl-CoA metabolic process
OCW38_RS03765	COG0037	tRNA processing
OCW38_RS03775	COG0347	Belongs to the P(II) protein family
OCW38_RS03780	COG3021	interspecies interaction between organisms
OCW38_RS03790	COG0741	lytic transglycosylase activity
OCW38_RS03790	COG1388	LysM domain
OCW38_RS03795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCW38_RS03800	COG2226	methyltransferase
OCW38_RS03805	COG3385	transposase activity
OCW38_RS03810	COG0328	RNA-DNA hybrid ribonuclease activity
OCW38_RS03815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OCW38_RS03825	COG1960	acyl-CoA dehydrogenase activity
OCW38_RS03830	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OCW38_RS03835	COG0121	glutamine amidotransferase
OCW38_RS03840	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OCW38_RS03845	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OCW38_RS03855	COG2233	PERMEase
OCW38_RS03875	COG1393	Belongs to the ArsC family
OCW38_RS03880	COG4783	chaperone-mediated protein folding
OCW38_RS03895	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OCW38_RS03900	COG2716	regulation of RNA biosynthetic process
OCW38_RS03905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OCW38_RS03910	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
OCW38_RS03925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OCW38_RS03930	COG1393	Belongs to the ArsC family
OCW38_RS03955	COG2837	iron assimilation
OCW38_RS03960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OCW38_RS03965	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OCW38_RS03975	COG2190	(PTS) system
OCW38_RS03985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCW38_RS03995	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
OCW38_RS04000	COG3115	cell septum assembly
OCW38_RS04005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OCW38_RS04030	COG0789	Transcriptional regulator
OCW38_RS04040	COG0330	HflC and HflK could
OCW38_RS04045	COG3118	belongs to the thioredoxin family
OCW38_RS04050	COG0300	oxidoreductase activity
OCW38_RS04055	COG1090	epimerase
OCW38_RS04080	COG0622	Phosphoesterase
OCW38_RS04095	COG3710	Transcriptional regulator
OCW38_RS04100	COG0326	Molecular chaperone. Has ATPase activity
OCW38_RS04105	COG0563	adenylate kinase activity
OCW38_RS04110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OCW38_RS04115	COG3104	oligopeptide transport
OCW38_RS04125	COG0367	asparagine synthase
OCW38_RS04130	COG4651	solute:proton antiporter activity
OCW38_RS04130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OCW38_RS04135	COG1940	carbohydrate kinase activity
OCW38_RS04135	COG1846	Transcriptional regulator
OCW38_RS04140	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OCW38_RS04145	COG2190	(PTS) system
OCW38_RS04145	COG1263	PTS System
OCW38_RS04145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCW38_RS04155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OCW38_RS04180	COG0596	Alpha beta hydrolase
OCW38_RS04185	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
OCW38_RS04190	COG0033	Phosphoglucomutase
OCW38_RS04200	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OCW38_RS04215	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OCW38_RS04220	COG1053	succinate dehydrogenase
OCW38_RS04225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OCW38_RS04230	COG0567	Dehydrogenase, E1 component
OCW38_RS04235	COG0508	dehydrogenase complex catalyzes the overall conversion of
OCW38_RS04240	COG0045	succinate-CoA ligase (ADP-forming) activity
OCW38_RS04250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OCW38_RS04255	COG1121	(ABC) transporter
OCW38_RS04260	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
OCW38_RS04275	COG1918	ferrous iron import across plasma membrane
OCW38_RS04295	COG0018	arginyl-trna synthetase
OCW38_RS04300	COG3102	Protein conserved in bacteria
OCW38_RS04305	COG0788	formyltetrahydrofolate deformylase activity
OCW38_RS04315	COG1199	ATP-dependent helicase activity
OCW38_RS04320	COG1214	PFAM Peptidase M22, glycoprotease
OCW38_RS04335	COG0596	Alpha beta hydrolase
OCW38_RS04340	COG0318	PFAM AMP-dependent synthetase and ligase
OCW38_RS04345	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
OCW38_RS04350	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OCW38_RS04355	COG2894	cell division
OCW38_RS04360	COG0850	regulation of cytokinetic process
OCW38_RS04365	COG3100	YcgL domain-containing protein
OCW38_RS04370	COG2951	lytic endotransglycosylase activity
OCW38_RS04375	COG0583	DNA-binding transcription factor activity
OCW38_RS04380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OCW38_RS04390	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OCW38_RS04400	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OCW38_RS04405	COG2860	membrane
OCW38_RS04410	COG3101	peptidyl-lysine hydroxylation
OCW38_RS04420	COG0431	NADPH-dependent FMN reductase
OCW38_RS04430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OCW38_RS04440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OCW38_RS04445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OCW38_RS04455	COG0101	tRNA pseudouridine synthase activity
OCW38_RS04460	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OCW38_RS04465	COG0285	dihydrofolate synthase activity
OCW38_RS04470	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
OCW38_RS04475	COG1286	toxin biosynthetic process
OCW38_RS04480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OCW38_RS04485	COG0583	DNA-binding transcription factor activity
OCW38_RS04490	COG0745	RESPONSE REGULATOR receiver
OCW38_RS04500	COG2832	Protein of unknown function (DUF454)
OCW38_RS04505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OCW38_RS04510	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OCW38_RS04515	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OCW38_RS04520	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OCW38_RS04525	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OCW38_RS04535	COG2983	Belongs to the UPF0260 family
OCW38_RS04540	COG1785	Belongs to the alkaline phosphatase family
OCW38_RS04560	COG2226	methyltransferase
OCW38_RS04575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OCW38_RS04580	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCW38_RS04590	COG3139	Protein of unknown function (DUF1315)
OCW38_RS04595	COG0252	asparaginase activity
OCW38_RS04600	COG0616	signal peptide processing
OCW38_RS04605	COG0446	pyridine nucleotide-disulphide oxidoreductase
OCW38_RS04605	COG1902	pentaerythritol trinitrate reductase activity
OCW38_RS04610	COG0778	Nitroreductase
OCW38_RS04615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OCW38_RS04630	COG0123	including yeast histone deacetylase and acetoin utilization protein
OCW38_RS04635	COG0840	transmembrane signaling receptor activity
OCW38_RS04650	COG3083	sulfuric ester hydrolase activity
OCW38_RS04655	COG3082	Protein of unknown function (DUF1414)
OCW38_RS04660	COG3081	Nucleoid-associated protein
OCW38_RS04675	COG1757	Na H antiporter
OCW38_RS04680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OCW38_RS04685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OCW38_RS04690	COG2095	MarC family integral membrane protein
OCW38_RS04695	COG1012	belongs to the aldehyde dehydrogenase family
OCW38_RS04695	COG1454	alcohol dehydrogenase
OCW38_RS04715	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OCW38_RS04725	COG2056	Na+-H+ antiporter family
OCW38_RS04735	COG2885	chlorophyll binding
OCW38_RS04745	COG0346	lactoylglutathione lyase activity
OCW38_RS04750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OCW38_RS04755	COG4660	Part of a membrane complex involved in electron transport
OCW38_RS04760	COG4659	FMN binding
OCW38_RS04765	COG4658	electron transport chain
OCW38_RS04770	COG4656	Part of a membrane complex involved in electron transport
OCW38_RS04775	COG2878	Part of a membrane complex involved in electron transport
OCW38_RS04780	COG4657	Part of a membrane complex involved in electron transport
OCW38_RS04785	COG1609	Transcriptional regulator
OCW38_RS04790	COG3250	beta-galactosidase activity
OCW38_RS04800	COG4580	involved in the transport of maltose and maltodextrins
OCW38_RS04810	COG2211	Major facilitator Superfamily
OCW38_RS04820	COG0556	nucleotide-excision repair
OCW38_RS04825	COG2204	response regulator
OCW38_RS04830	COG2198	Histidine kinase
OCW38_RS04835	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OCW38_RS04840	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OCW38_RS04845	COG0521	Mo-molybdopterin cofactor biosynthetic process
OCW38_RS04850	COG0315	cyclic pyranopterin monophosphate synthase activity
OCW38_RS04855	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OCW38_RS04860	COG0314	molybdopterin synthase activity
OCW38_RS04870	COG0601	transmembrane transport
OCW38_RS04875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCW38_RS04880	COG0444	Belongs to the ABC transporter superfamily
OCW38_RS04890	COG0435	Glutathione S-transferase
OCW38_RS04895	COG0280	phosphate acetyltransferase
OCW38_RS04895	COG0857	belongs to the CobB CobQ family
OCW38_RS04900	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OCW38_RS04905	COG3092	negative regulation of chromosome organization
OCW38_RS04915	COG3706	GGDEF domain
OCW38_RS04920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OCW38_RS04925	COG0653	protein targeting
OCW38_RS04930	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OCW38_RS04935	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OCW38_RS04940	COG2186	Transcriptional regulator
OCW38_RS04950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCW38_RS04950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCW38_RS04955	COG0489	protein tyrosine kinase activity
OCW38_RS04960	COG0572	uridine kinase
OCW38_RS04965	COG2982	Protein involved in outer membrane biogenesis
OCW38_RS04970	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
OCW38_RS04975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OCW38_RS04980	COG0659	secondary active sulfate transmembrane transporter activity
OCW38_RS04985	COG1530	ribonuclease E activity
OCW38_RS04990	COG0564	pseudouridine synthase activity
OCW38_RS05000	COG1399	metal-binding, possibly nucleic acid-binding protein
OCW38_RS05005	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OCW38_RS05010	COG0416	fatty acid biosynthetic process
OCW38_RS05015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OCW38_RS05040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OCW38_RS05045	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OCW38_RS05060	COG0084	hydrolase, TatD family'
OCW38_RS05080	COG4667	esterase of the alpha-beta hydrolase superfamily
OCW38_RS05085	COG3344	reverse transcriptase
OCW38_RS05090	COG0469	pyruvate kinase activity
OCW38_RS05095	COG1940	carbohydrate kinase activity
OCW38_RS05100	COG0784	Response regulator, receiver
OCW38_RS05100	COG0835	chemotaxis
OCW38_RS05115	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OCW38_RS05120	COG1028	Short-chain dehydrogenase reductase Sdr
OCW38_RS05125	COG0616	signal peptide processing
OCW38_RS05130	COG2719	SpoVR family
OCW38_RS05135	COG2718	Belongs to the UPF0229 family
OCW38_RS05140	COG2766	serine protein kinase
OCW38_RS05150	COG3013	Belongs to the UPF0304 family
OCW38_RS05155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OCW38_RS05165	COG1882	Formate acetyltransferase
OCW38_RS05180	COG3385	transposase activity
OCW38_RS05200	COG4160	amino acid transport
OCW38_RS05205	COG0708	Exodeoxyribonuclease III
OCW38_RS05210	COG1770	oligopeptidase
OCW38_RS05215	COG2814	Major facilitator Superfamily
OCW38_RS05220	COG0840	transmembrane signaling receptor activity
OCW38_RS05225	COG3344	reverse transcriptase
OCW38_RS05230	COG2850	peptidyl-arginine hydroxylation
OCW38_RS05250	COG1199	ATP-dependent helicase activity
OCW38_RS05260	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OCW38_RS05265	COG1187	pseudouridine synthase activity
OCW38_RS05275	COG1278	Cold shock
OCW38_RS05280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OCW38_RS05285	COG0542	response to heat
OCW38_RS05290	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OCW38_RS05295	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OCW38_RS05300	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OCW38_RS05310	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OCW38_RS05320	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OCW38_RS05325	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OCW38_RS05330	COG0297	glycogen (starch) synthase activity
OCW38_RS05350	COG3070	regulator of competence-specific genes
OCW38_RS05355	COG1609	Transcriptional regulator
OCW38_RS05360	COG3381	protein complex oligomerization
OCW38_RS05365	COG0745	RESPONSE REGULATOR receiver
OCW38_RS05370	COG1434	Gram-negative-bacterium-type cell wall biogenesis
OCW38_RS05375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCW38_RS05380	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
OCW38_RS05385	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
OCW38_RS05390	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
OCW38_RS05395	COG3344	reverse transcriptase
OCW38_RS05400	COG3383	formate dehydrogenase (NAD+) activity
OCW38_RS05415	COG4067	protein conserved in archaea
OCW38_RS05415	COG0189	ligase activity
OCW38_RS05420	COG0500	methyltransferase
OCW38_RS05425	COG4106	trans-aconitate 2-methyltransferase activity
OCW38_RS05430	COG1801	Protein of unknown function DUF72
OCW38_RS05435	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OCW38_RS05440	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OCW38_RS05445	COG0632	four-way junction helicase activity
OCW38_RS05450	COG2255	four-way junction helicase activity
OCW38_RS05455	COG1271	oxidase subunit
OCW38_RS05460	COG1294	oxidase, subunit
OCW38_RS05465	COG4890	Cyd operon protein YbgT
OCW38_RS05475	COG0824	Thioesterase
OCW38_RS05480	COG0811	peptide transport
OCW38_RS05495	COG0823	Involved in the tonB-independent uptake of proteins
OCW38_RS05500	COG2885	chlorophyll binding
OCW38_RS05505	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
OCW38_RS05510	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OCW38_RS05525	COG0784	Response regulator, receiver
OCW38_RS05525	COG5002	protein histidine kinase activity
OCW38_RS05540	COG0786	glutamate:sodium symporter activity
OCW38_RS05565	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OCW38_RS05575	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
OCW38_RS05575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OCW38_RS05580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OCW38_RS05600	COG0745	RESPONSE REGULATOR receiver
OCW38_RS05605	COG0463	Glycosyl transferase, family 2
OCW38_RS05620	COG3135	benzoate transporter
OCW38_RS05625	COG1396	sequence-specific DNA binding
OCW38_RS05630	COG1032	radical SAM domain protein
OCW38_RS05645	COG0583	DNA-binding transcription factor activity
OCW38_RS05650	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OCW38_RS05660	COG2350	Protein conserved in bacteria
OCW38_RS05665	COG1607	acyl-coa hydrolase
OCW38_RS05670	COG2917	probably involved in intracellular septation
OCW38_RS05685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OCW38_RS05690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCW38_RS05700	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OCW38_RS05710	COG1301	dicarboxylic acid transport
OCW38_RS05715	COG0159	tryptophan synthase activity
OCW38_RS05720	COG0133	tryptophan synthase activity
OCW38_RS05725	COG0134	indole-3-glycerol-phosphate synthase activity
OCW38_RS05725	COG0135	phosphoribosylanthranilate isomerase activity
OCW38_RS05730	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OCW38_RS05735	COG0512	Glutamine amidotransferase of anthranilate synthase
OCW38_RS05740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OCW38_RS05750	COG0613	PHP domain protein
OCW38_RS05755	COG0009	L-threonylcarbamoyladenylate synthase
OCW38_RS05760	COG1187	pseudouridine synthase activity
OCW38_RS05765	COG3385	transposase activity
OCW38_RS05780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OCW38_RS05790	COG0417	DNA replication proofreading
OCW38_RS05795	COG2197	response regulator
OCW38_RS05800	COG0322	excinuclease ABC activity
OCW38_RS05840	COG0019	diaminopimelate decarboxylase activity
OCW38_RS05850	COG3385	transposase activity
OCW38_RS05865	COG3302	dmso reductase anchor subunit
OCW38_RS05870	COG0437	4 iron, 4 sulfur cluster binding
OCW38_RS05875	COG0243	molybdopterin cofactor binding
OCW38_RS05895	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OCW38_RS05900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OCW38_RS05905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCW38_RS05920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OCW38_RS05930	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
OCW38_RS05935	COG0437	4 iron, 4 sulfur cluster binding
OCW38_RS05940	COG3301	Polysulphide reductase, NrfD
OCW38_RS05945	COG1138	Cytochrome C-type biogenesis protein
OCW38_RS05955	COG3088	subunit of a heme lyase
OCW38_RS05955	COG4235	cytochrome complex assembly
OCW38_RS05965	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OCW38_RS05990	COG2989	Protein conserved in bacteria
OCW38_RS05995	COG3108	Peptidase M15
OCW38_RS06000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCW38_RS06015	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OCW38_RS06040	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OCW38_RS06045	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OCW38_RS06050	COG0840	transmembrane signaling receptor activity
OCW38_RS06055	COG3344	reverse transcriptase
OCW38_RS06060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OCW38_RS06065	COG4988	ABC transporter
OCW38_RS06070	COG0492	ferredoxin-NADP+ reductase activity
OCW38_RS06075	COG3706	GGDEF domain
OCW38_RS06085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OCW38_RS06115	COG0471	metal ion transport
OCW38_RS06120	COG2949	membrane
OCW38_RS06125	COG0281	malic enzyme
OCW38_RS06130	COG1643	Atp-dependent helicase
OCW38_RS06140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OCW38_RS06175	COG0277	FAD linked oxidase domain protein
OCW38_RS06175	COG0247	lactate metabolic process
OCW38_RS06190	COG2986	histidine ammonia-lyase
OCW38_RS06195	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OCW38_RS06200	COG0010	Belongs to the arginase family
OCW38_RS06205	COG1228	amidohydrolase
OCW38_RS06215	COG4326	sporulation control protein
OCW38_RS06235	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OCW38_RS06240	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OCW38_RS06245	COG3097	Belongs to the UPF0267 family
OCW38_RS06260	COG0488	(ABC) transporter
OCW38_RS06265	COG1309	transcriptional regulator
OCW38_RS06275	COG1166	arginine decarboxylase activity
OCW38_RS06280	COG0010	Belongs to the arginase family
OCW38_RS06290	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OCW38_RS06295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCW38_RS06300	COG0800	Aldolase
OCW38_RS06305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCW38_RS06310	COG1917	Cupin 2, conserved barrel domain protein
OCW38_RS06335	COG3639	organic phosphonate transmembrane transporter activity
OCW38_RS06340	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
OCW38_RS06350	COG2186	Transcriptional regulator
OCW38_RS06365	COG3181	Tripartite tricarboxylate transporter family receptor
OCW38_RS06375	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCW38_RS06390	COG0840	transmembrane signaling receptor activity
OCW38_RS06425	COG2186	Transcriptional regulator
OCW38_RS06430	COG1028	Short-chain dehydrogenase reductase Sdr
OCW38_RS06435	COG2186	Transcriptional regulator
OCW38_RS06440	COG0517	IMP dehydrogenase activity
OCW38_RS06445	COG2176	DNA-directed DNA polymerase activity
OCW38_RS06470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCW38_RS06495	COG3033	Beta-eliminating lyase
OCW38_RS06540	COG5433	transposase activity
OCW38_RS06550	COG0471	metal ion transport
OCW38_RS06555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCW38_RS06555	COG4191	Histidine kinase
OCW38_RS06595	COG0730	response to heat
OCW38_RS06605	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OCW38_RS06610	COG1280	lysine exporter protein (LysE YggA)
OCW38_RS06615	COG1115	amino acid carrier protein
OCW38_RS06635	COG1115	amino acid carrier protein
OCW38_RS06650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCW38_RS06665	COG3290	protein histidine kinase activity
OCW38_RS06670	COG4565	transcriptional regulatory protein
OCW38_RS06675	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OCW38_RS06680	COG0363	glucosamine-6-phosphate deaminase activity
OCW38_RS06685	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OCW38_RS06695	COG4628	conserved protein (DUF2132)
OCW38_RS06735	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OCW38_RS06740	COG0372	Belongs to the citrate synthase family
OCW38_RS06745	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OCW38_RS06750	COG2828	Protein conserved in bacteria
OCW38_RS06780	COG0561	phosphatase activity
OCW38_RS06785	COG0602	queuosine metabolic process
OCW38_RS06790	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OCW38_RS06795	COG3706	GGDEF domain
OCW38_RS06805	COG2885	chlorophyll binding
OCW38_RS06805	COG3047	cAMP biosynthetic process
OCW38_RS06825	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OCW38_RS06835	COG1254	Belongs to the acylphosphatase family
OCW38_RS06840	COG2920	part of a sulfur-relay system
OCW38_RS06845	COG0670	Belongs to the BI1 family
OCW38_RS06850	COG1126	abc transporter atp-binding protein
OCW38_RS06855	COG0765	amino acid transport
OCW38_RS06860	COG4597	amino acid ABC transporter
OCW38_RS06865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCW38_RS06875	COG1666	GTP binding
OCW38_RS06880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OCW38_RS06885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OCW38_RS06885	COG0574	Belongs to the PEP-utilizing enzyme family
OCW38_RS06900	COG2996	Protein conserved in bacteria
OCW38_RS06905	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
OCW38_RS06905	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OCW38_RS06910	COG3008	intermembrane lipid transfer
OCW38_RS06915	COG2995	paraquat-inducible protein a
OCW38_RS06920	COG1132	(ABC) transporter
OCW38_RS06925	COG1956	GAF domain-containing protein
OCW38_RS06930	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
OCW38_RS06945	COG0308	aminopeptidase N
OCW38_RS06955	COG2902	Dehydrogenase
OCW38_RS06960	COG0167	dihydroorotate dehydrogenase activity
OCW38_RS06970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OCW38_RS06970	COG0116	Belongs to the methyltransferase superfamily
OCW38_RS06980	COG0488	(ABC) transporter
OCW38_RS07000	COG1067	ATP-dependent peptidase activity
OCW38_RS07005	COG3120	sequence-specific DNA binding
OCW38_RS07040	COG5002	protein histidine kinase activity
OCW38_RS07040	COG0784	Response regulator, receiver
OCW38_RS07055	COG3278	Belongs to the heme-copper respiratory oxidase family
OCW38_RS07070	COG2010	Cytochrome c
OCW38_RS07080	COG2217	Heavy metal translocating P-type atpase
OCW38_RS07095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OCW38_RS07100	COG0589	response to stress
OCW38_RS07105	COG0037	tRNA processing
OCW38_RS07125	COG3842	ATPase activity
OCW38_RS07130	COG1176	ABC-type spermidine putrescine transport system, permease component I
OCW38_RS07135	COG1177	transmembrane transport
OCW38_RS07145	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OCW38_RS07150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OCW38_RS07155	COG0004	ammonium transporteR
OCW38_RS07170	COG0437	4 iron, 4 sulfur cluster binding
OCW38_RS07175	COG0243	molybdopterin cofactor binding
OCW38_RS07175	COG3383	formate dehydrogenase (NAD+) activity
OCW38_RS07185	COG3381	protein complex oligomerization
OCW38_RS07205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OCW38_RS07210	COG0488	(ABC) transporter
OCW38_RS07230	COG4191	Histidine kinase
OCW38_RS07245	COG4662	Binding-protein-dependent transport system inner membrane component
OCW38_RS07250	COG3842	ATPase activity
OCW38_RS07255	COG0746	molybdenum cofactor guanylyltransferase activity
OCW38_RS07260	COG0303	'Molybdopterin
OCW38_RS07270	COG1940	carbohydrate kinase activity
OCW38_RS07275	COG3148	PFAM DTW domain containing protein
OCW38_RS07290	COG0791	NLP P60 protein
OCW38_RS07310	COG0307	riboflavin synthase, alpha
OCW38_RS07315	COG0534	Mate efflux family protein
OCW38_RS07320	COG1793	dna ligase
OCW38_RS07330	COG2885	chlorophyll binding
OCW38_RS07330	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OCW38_RS07350	COG4176	ABC-type proline glycine betaine transport system permease component
OCW38_RS07355	COG3448	diguanylate cyclase activity
OCW38_RS07355	COG4175	Glycine betaine
OCW38_RS07365	COG2204	response regulator
OCW38_RS07400	COG1215	transferase activity, transferring glycosyl groups
OCW38_RS07405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OCW38_RS07410	COG0583	DNA-binding transcription factor activity
OCW38_RS07440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCW38_RS07445	COG0583	DNA-binding transcription factor activity
OCW38_RS07455	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
OCW38_RS07460	COG3385	transposase activity
OCW38_RS07480	COG1742	UPF0060 membrane protein
OCW38_RS07575	COG4974	Belongs to the 'phage' integrase family
OCW38_RS07595	COG4160	amino acid transport
OCW38_RS07600	COG4215	(ABC) transporter
OCW38_RS07605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCW38_RS07610	COG1126	abc transporter atp-binding protein
OCW38_RS07625	COG0826	peptidase U32
OCW38_RS07655	COG1028	Short-chain dehydrogenase reductase Sdr
OCW38_RS07665	COG0653	protein targeting
OCW38_RS07710	COG1187	pseudouridine synthase activity
OCW38_RS07725	COG0494	nUDIX hydrolase
OCW38_RS07745	COG0584	glycerophosphoryl diester phosphodiesterase
OCW38_RS07750	COG2271	Major facilitator Superfamily
OCW38_RS07780	COG4774	siderophore transport
OCW38_RS07800	COG4615	Cyclic peptide transporter
OCW38_RS07810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OCW38_RS07815	COG1120	ATPase activity
OCW38_RS07820	COG2977	Belongs to the P-Pant transferase superfamily
OCW38_RS07845	COG0415	Belongs to the DNA photolyase family
OCW38_RS07850	COG3046	protein related to deoxyribodipyrimidine photolyase
OCW38_RS07870	COG0419	ATPase involved in DNA repair
OCW38_RS07875	COG0420	3'-5' exonuclease activity
OCW38_RS07880	COG0346	lactoylglutathione lyase activity
OCW38_RS07895	COG0454	-acetyltransferase
OCW38_RS07905	COG4771	TonB-dependent receptor
OCW38_RS07915	COG3469	chitinase activity
OCW38_RS07935	COG3344	reverse transcriptase
OCW38_RS07940	COG0840	transmembrane signaling receptor activity
OCW38_RS07955	COG0583	DNA-binding transcription factor activity
OCW38_RS07960	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OCW38_RS08005	COG0494	nUDIX hydrolase
OCW38_RS08045	COG0463	Glycosyl transferase, family 2
OCW38_RS08060	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OCW38_RS08075	COG5499	transcription regulator containing HTH domain
OCW38_RS08080	COG4680	protein conserved in bacteria
OCW38_RS08090	COG0582	viral genome integration into host DNA
OCW38_RS08120	COG2195	Cleaves the N-terminal amino acid of tripeptides
OCW38_RS08135	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
OCW38_RS08140	COG3063	Type IV pilus biogenesis stability protein PilW
OCW38_RS08150	COG1451	nucleotide metabolic process
OCW38_RS08160	COG0583	DNA-binding transcription factor activity
OCW38_RS08165	COG2814	Major facilitator Superfamily
OCW38_RS08175	COG3706	GGDEF domain
OCW38_RS08185	COG1247	-acetyltransferase
OCW38_RS08205	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
OCW38_RS08210	COG4139	cobalamin transport
OCW38_RS08215	COG2988	succinylglutamate desuccinylase activity
OCW38_RS08235	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
OCW38_RS08240	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OCW38_RS08245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OCW38_RS08250	COG0702	epimerase
OCW38_RS08255	COG1823	symporter activity
OCW38_RS08265	COG4989	oxidoreductase activity
OCW38_RS08280	COG3122	Protein conserved in bacteria
OCW38_RS08285	COG3568	Endonuclease Exonuclease Phosphatase
OCW38_RS08330	COG2925	Exonuclease
OCW38_RS08340	COG1346	cytolysis
OCW38_RS08345	COG0295	cytidine deaminase activity
OCW38_RS08350	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OCW38_RS08355	COG0500	methyltransferase
OCW38_RS08365	COG0776	regulation of translation
OCW38_RS08375	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OCW38_RS08385	COG0523	cobalamin synthesis protein
OCW38_RS08390	COG2988	succinylglutamate desuccinylase activity
OCW38_RS08400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OCW38_RS08415	COG5433	transposase activity
OCW38_RS08430	COG0583	DNA-binding transcription factor activity
OCW38_RS08470	COG0776	regulation of translation
OCW38_RS08505	COG1342	Belongs to the UPF0251 family
OCW38_RS08520	COG3683	transport system, periplasmic component
OCW38_RS08525	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
OCW38_RS08530	COG1464	Belongs to the NlpA lipoprotein family
OCW38_RS08550	COG1595	DNA-templated transcription, initiation
OCW38_RS08585	COG0072	phenylalanine-tRNA ligase activity
OCW38_RS08585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCW38_RS08590	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OCW38_RS08635	COG1643	Atp-dependent helicase
OCW38_RS08685	COG3706	GGDEF domain
OCW38_RS08700	COG0443	Heat shock 70 kDa protein
OCW38_RS08715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCW38_RS08730	COG3106	COG3106 Predicted ATPase
OCW38_RS08745	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OCW38_RS08760	COG0494	nUDIX hydrolase
OCW38_RS08765	COG0814	amino acid
OCW38_RS08770	COG1760	l-serine dehydratase
OCW38_RS08775	COG0814	amino acid
OCW38_RS08785	COG0720	synthase
OCW38_RS08790	COG0840	transmembrane signaling receptor activity
OCW38_RS08795	COG0659	secondary active sulfate transmembrane transporter activity
OCW38_RS08800	COG0017	Asparaginyl-tRNA synthetase
OCW38_RS08810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OCW38_RS08820	COG2770	Histidine kinase
OCW38_RS08820	COG3437	response regulator, receiver
OCW38_RS08825	COG1448	Aminotransferase
OCW38_RS08855	COG2258	MOSC domain
OCW38_RS08865	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OCW38_RS08875	COG3852	Histidine kinase
OCW38_RS08880	COG2204	response regulator
OCW38_RS08890	COG3070	regulator of competence-specific genes
OCW38_RS08900	COG2431	L-lysine efflux transmembrane transporter activity
OCW38_RS08910	COG0076	glutamate decarboxylase activity
OCW38_RS08915	COG1737	Transcriptional regulator
OCW38_RS08925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OCW38_RS08930	COG3385	transposase activity
OCW38_RS08935	COG2985	domain, Protein
OCW38_RS08935	COG3273	potassium ion transport
OCW38_RS08940	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OCW38_RS08945	COG3385	transposase activity
OCW38_RS08965	COG2885	chlorophyll binding
OCW38_RS08965	COG3047	cAMP biosynthetic process
OCW38_RS08970	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OCW38_RS08995	COG0702	epimerase
OCW38_RS09005	COG2814	Major facilitator Superfamily
OCW38_RS09015	COG1061	Type III restriction enzyme res subunit
OCW38_RS09030	COG0642	Histidine kinase
OCW38_RS09050	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OCW38_RS09110	COG2113	Glycine betaine
OCW38_RS09115	COG4176	ABC-type proline glycine betaine transport system permease component
OCW38_RS09140	COG2866	Carboxypeptidase
OCW38_RS09150	COG0513	Belongs to the DEAD box helicase family
OCW38_RS09170	COG3313	Fe-S protein
OCW38_RS09180	COG4134	Bacterial extracellular solute-binding protein
OCW38_RS09185	COG4135	transport system, permease component
OCW38_RS09190	COG4136	ATPase activity
OCW38_RS09195	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OCW38_RS09200	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OCW38_RS09200	COG0116	Belongs to the methyltransferase superfamily
OCW38_RS09205	COG0564	pseudouridine synthase activity
OCW38_RS09215	COG0733	neurotransmitter:sodium symporter activity
OCW38_RS09225	COG0626	cystathionine gamma-synthase activity
OCW38_RS09230	COG2818	Glycosylase
OCW38_RS09245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCW38_RS09250	COG1983	PspC domain protein
OCW38_RS09260	COG1842	Phage shock protein A
OCW38_RS09265	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OCW38_RS09270	COG4166	transmembrane transport
OCW38_RS09275	COG4168	peptide transport system, permease
OCW38_RS09280	COG4171	peptide transport system, permease
OCW38_RS09290	COG4172	Belongs to the ABC transporter superfamily
OCW38_RS09305	COG1227	inorganic diphosphatase activity
OCW38_RS09315	COG0243	molybdopterin cofactor binding
OCW38_RS09320	COG3005	denitrification pathway
OCW38_RS09325	COG4459	periplasmic nitrate reductase
OCW38_RS09330	COG0390	transport system, permease component
OCW38_RS09335	COG2116	formate transmembrane transporter activity
OCW38_RS09365	COG0215	cysteine-tRNA ligase activity
OCW38_RS09370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OCW38_RS09375	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCW38_RS09380	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OCW38_RS09385	COG3012	SEC-C Motif Domain Protein
OCW38_RS09390	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OCW38_RS09390	COG0140	phosphoribosyl-ATP diphosphatase activity
OCW38_RS09395	COG0107	imidazoleglycerol-phosphate synthase activity
OCW38_RS09400	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OCW38_RS09405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OCW38_RS09410	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OCW38_RS09410	COG0131	Imidazoleglycerol-phosphate dehydratase
OCW38_RS09415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OCW38_RS09430	COG1757	Na H antiporter
OCW38_RS09435	COG2916	Histone family protein nucleoid-structuring protein H-NS
OCW38_RS09440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCW38_RS09455	COG2915	High frequency lysogenization protein hflD homolog
OCW38_RS09460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OCW38_RS09465	COG0501	Belongs to the peptidase M48B family
OCW38_RS09485	COG0156	8-amino-7-oxononanoate synthase activity
OCW38_RS09490	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OCW38_RS09495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OCW38_RS09500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OCW38_RS09505	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OCW38_RS09510	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OCW38_RS09515	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OCW38_RS09525	COG1522	sequence-specific DNA binding
OCW38_RS09530	COG0686	Belongs to the AlaDH PNT family
OCW38_RS09540	COG0583	DNA-binding transcription factor activity
OCW38_RS09555	COG0284	orotidine-5'-phosphate decarboxylase activity
OCW38_RS09560	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
OCW38_RS09565	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
OCW38_RS09570	COG0776	regulation of translation
OCW38_RS09575	COG0539	negative regulation of cytoplasmic translation
OCW38_RS09580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OCW38_RS09585	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OCW38_RS09590	COG2835	tetraacyldisaccharide 4'-kinase activity
OCW38_RS09595	COG1663	tetraacyldisaccharide 4'-kinase activity
OCW38_RS09600	COG1132	(ABC) transporter
OCW38_RS09605	COG2333	competence protein COMEC
OCW38_RS09605	COG0658	competence protein
OCW38_RS09615	COG4591	ABC-type transport system involved in lipoprotein release permease component
OCW38_RS09620	COG1136	(ABC) transporter
OCW38_RS09625	COG4591	ABC-type transport system involved in lipoprotein release permease component
OCW38_RS09635	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OCW38_RS09645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCW38_RS09650	COG1252	NADH dehydrogenase
OCW38_RS09655	COG3150	esterase
OCW38_RS09680	COG0537	adenosine 5'-monophosphoramidase activity
OCW38_RS09710	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OCW38_RS09710	COG0517	IMP dehydrogenase activity
OCW38_RS09710	COG0617	tRNA 3'-terminal CCA addition
OCW38_RS09735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OCW38_RS09750	COG0346	lactoylglutathione lyase activity
OCW38_RS09770	COG2015	COG2015, Alkyl sulfatase and related hydrolases
OCW38_RS09785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OCW38_RS09790	COG1845	cytochrome c oxidase, subunit III
OCW38_RS09795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OCW38_RS09800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OCW38_RS09805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCW38_RS09815	COG1309	transcriptional regulator
OCW38_RS09820	COG3040	lipid binding
OCW38_RS09845	COG2199	diguanylate cyclase activity
OCW38_RS09845	COG2200	EAL domain
OCW38_RS09845	COG2202	Pas domain
OCW38_RS09860	COG2433	Pfam Transposase IS66
OCW38_RS09865	COG1227	inorganic diphosphatase activity
OCW38_RS09870	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OCW38_RS09890	COG2233	PERMEase
OCW38_RS09910	COG1280	lysine exporter protein (LysE YggA)
OCW38_RS09915	COG1522	sequence-specific DNA binding
OCW38_RS09935	COG0789	Transcriptional regulator
OCW38_RS09950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OCW38_RS09975	COG0463	Glycosyl transferase, family 2
OCW38_RS09975	COG1216	Glycosyl transferase, family 2
OCW38_RS09980	COG0438	transferase activity, transferring glycosyl groups
OCW38_RS09985	COG0328	RNA-DNA hybrid ribonuclease activity
OCW38_RS09985	COG3341	Caulimovirus viroplasmin
OCW38_RS10015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCW38_RS10020	COG3385	transposase activity
OCW38_RS10040	COG3126	Type III secretion system lipoprotein chaperone (YscW)
OCW38_RS10045	COG1946	Acyl-CoA thioesterase
OCW38_RS10055	COG1522	sequence-specific DNA binding
OCW38_RS10060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OCW38_RS10070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCW38_RS10130	COG2855	membrane
OCW38_RS10145	COG2190	(PTS) system
OCW38_RS10145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCW38_RS10145	COG1263	PTS System
OCW38_RS10160	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OCW38_RS10165	COG2267	carboxylic ester hydrolase activity
OCW38_RS10170	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OCW38_RS10175	COG1169	isochorismate synthase
OCW38_RS10180	COG0436	Aminotransferase
OCW38_RS10185	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
OCW38_RS10190	COG0232	Belongs to the dGTPase family. Type 2 subfamily
OCW38_RS10205	COG1555	photosystem II stabilization
OCW38_RS10210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OCW38_RS10215	COG0776	regulation of translation
OCW38_RS10220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OCW38_RS10225	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OCW38_RS10230	COG0740	serine-type endopeptidase activity
OCW38_RS10235	COG0544	peptidyl-prolyl cis-trans isomerase activity
OCW38_RS10255	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OCW38_RS10260	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OCW38_RS10265	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OCW38_RS10280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OCW38_RS10280	COG3321	synthase
OCW38_RS10295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OCW38_RS10295	COG2070	2-Nitropropane dioxygenase
OCW38_RS10300	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OCW38_RS10305	COG3842	ATPase activity
OCW38_RS10315	COG1175	transmembrane transport
OCW38_RS10335	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OCW38_RS10340	COG1280	lysine exporter protein (LysE YggA)
OCW38_RS10345	COG2890	protein-(glutamine-N5) methyltransferase activity
OCW38_RS10350	COG2840	Smr protein MutS2
OCW38_RS10355	COG2062	phosphohistidine phosphatase, SixA
OCW38_RS10365	COG1024	Enoyl-CoA hydratase
OCW38_RS10365	COG1250	3-hydroxyacyl-CoA dehydrogenase
OCW38_RS10370	COG0183	Belongs to the thiolase family
OCW38_RS10385	COG2067	long-chain fatty acid transport protein
OCW38_RS10390	COG2067	long-chain fatty acid transport protein
OCW38_RS10395	COG2853	Lipoprotein
OCW38_RS10400	COG3088	subunit of a heme lyase
OCW38_RS10400	COG4235	cytochrome complex assembly
OCW38_RS10410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OCW38_RS10415	COG1138	Cytochrome C-type biogenesis protein
OCW38_RS10420	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OCW38_RS10425	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OCW38_RS10430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OCW38_RS10435	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OCW38_RS10440	COG4133	protoheme IX ABC transporter activity
OCW38_RS10450	COG0835	chemotaxis
OCW38_RS10460	COG1192	Involved in chromosome partitioning
OCW38_RS10465	COG2201	protein-glutamate methylesterase activity
OCW38_RS10470	COG2198	Histidine kinase
OCW38_RS10470	COG0784	Response regulator, receiver
OCW38_RS10470	COG0643	Histidine kinase
OCW38_RS10475	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
OCW38_RS10510	COG1684	flagellar biosynthetic protein fliR
OCW38_RS10515	COG1987	bacterial-type flagellum assembly
OCW38_RS10565	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OCW38_RS10575	COG1677	Flagellar hook-basal body complex protein FliE
OCW38_RS10595	COG1516	flagellar protein fliS
OCW38_RS10605	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OCW38_RS10615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OCW38_RS10620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OCW38_RS10625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OCW38_RS10640	COG1705	Flagellar rod assembly protein muramidase FlgJ
OCW38_RS10640	COG3951	Flagellar rod assembly protein muramidase FlgJ
OCW38_RS10645	COG1706	bacterial-type flagellum-dependent cell motility
OCW38_RS10650	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
OCW38_RS10660	COG4787	bacterial-type flagellum-dependent cell motility
OCW38_RS10665	COG1749	Flagellar hook protein flgE
OCW38_RS10675	COG1558	bacterial-type flagellum-dependent cell motility
OCW38_RS10680	COG1815	bacterial-type flagellum-dependent cell motility
OCW38_RS10685	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OCW38_RS10690	COG0835	chemotaxis
OCW38_RS10690	COG0784	Response regulator, receiver
OCW38_RS10695	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
OCW38_RS10755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OCW38_RS10760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OCW38_RS10780	COG1216	Glycosyl transferase, family 2
OCW38_RS10820	COG1028	Short-chain dehydrogenase reductase Sdr
OCW38_RS10840	COG2217	Heavy metal translocating P-type atpase
OCW38_RS10840	COG2608	mercury ion transmembrane transporter activity
OCW38_RS10910	COG2840	Smr protein MutS2
OCW38_RS10915	COG1187	pseudouridine synthase activity
OCW38_RS10920	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OCW38_RS10930	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OCW38_RS10935	COG2912	Transglutaminase-like superfamily
OCW38_RS10940	COG3094	Invasion gene expression up-regulator, SirB
OCW38_RS10945	COG2890	protein-(glutamine-N5) methyltransferase activity
OCW38_RS10950	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OCW38_RS10955	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OCW38_RS10960	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OCW38_RS10965	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OCW38_RS10970	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OCW38_RS10975	COG0193	aminoacyl-tRNA hydrolase activity
OCW38_RS11080	COG2706	6-phosphogluconolactonase activity
OCW38_RS11085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OCW38_RS11095	COG1702	phosphate starvation-inducible protein PhoH
OCW38_RS11100	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OCW38_RS11105	COG4535	Mg2 and Co2 transporter CorC
OCW38_RS11110	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OCW38_RS11115	COG2888	peptidyl-tyrosine sulfation
OCW38_RS11120	COG0495	leucyl-tRNA aminoacylation
OCW38_RS11125	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
OCW38_RS11130	COG1466	dna polymerase III delta subunit
OCW38_RS11135	COG0799	negative regulation of ribosome biogenesis
OCW38_RS11140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OCW38_RS11145	COG0768	penicillin binding
OCW38_RS11150	COG0772	Belongs to the SEDS family
OCW38_RS11155	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OCW38_RS11160	COG1686	Belongs to the peptidase S11 family
OCW38_RS11170	COG0321	lipoyl(octanoyl) transferase activity
OCW38_RS11175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OCW38_RS11180	COG0733	neurotransmitter:sodium symporter activity
OCW38_RS11190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OCW38_RS11200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OCW38_RS11210	COG2991	Protein conserved in bacteria
OCW38_RS11215	COG1477	protein flavinylation
OCW38_RS11220	COG2871	sodium ion transport
OCW38_RS11225	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OCW38_RS11230	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OCW38_RS11240	COG1805	sodium ion transport
OCW38_RS11245	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OCW38_RS11250	COG0271	Belongs to the BolA IbaG family
OCW38_RS11255	COG2813	Specifically methylates the guanine in position
OCW38_RS11265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OCW38_RS11285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OCW38_RS11290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OCW38_RS11295	COG2166	iron-sulfur cluster assembly
OCW38_RS11300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OCW38_RS11305	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
OCW38_RS11315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OCW38_RS11315	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OCW38_RS11325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OCW38_RS11330	COG1074	ATP-dependent DNA helicase activity
OCW38_RS11335	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OCW38_RS11350	COG3141	response to X-ray
OCW38_RS11365	COG2095	MarC family integral membrane protein
OCW38_RS11370	COG0737	Belongs to the 5'-nucleotidase family
OCW38_RS11375	COG2171	N-acyltransferase activity
OCW38_RS11385	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OCW38_RS11385	COG0047	phosphoribosylformylglycinamidine synthase activity
OCW38_RS11405	COG1253	flavin adenine dinucleotide binding
OCW38_RS11410	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OCW38_RS11445	COG0484	heat shock protein binding
OCW38_RS11450	COG0443	Heat shock 70 kDa protein
OCW38_RS11460	COG3344	reverse transcriptase
OCW38_RS11465	COG1301	dicarboxylic acid transport
OCW38_RS11470	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OCW38_RS11475	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OCW38_RS11480	COG0497	DNA recombination
OCW38_RS11485	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCW38_RS11490	COG2914	Belongs to the UPF0125 (RnfH) family
OCW38_RS11495	COG2867	negative regulation of translational initiation
OCW38_RS11510	COG0189	ligase activity
OCW38_RS11510	COG4067	protein conserved in archaea
OCW38_RS11525	COG2391	methyltransferase activity
OCW38_RS11540	COG1104	cysteine desulfurase activity
OCW38_RS11560	COG0556	nucleotide-excision repair
OCW38_RS11595	COG0204	Acyl-transferase
OCW38_RS11600	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OCW38_RS11605	COG1115	amino acid carrier protein
OCW38_RS11610	COG1584	GPR1 FUN34 yaaH family protein
OCW38_RS11615	COG1757	Na H antiporter
OCW38_RS11625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OCW38_RS11625	COG0519	Catalyzes the synthesis of GMP from XMP
OCW38_RS11630	COG0516	GMP reductase activity
OCW38_RS11630	COG0517	IMP dehydrogenase activity
OCW38_RS11635	COG1570	exodeoxyribonuclease VII activity
OCW38_RS11640	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OCW38_RS11655	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
OCW38_RS11660	COG0804	urea catabolic process
OCW38_RS11665	COG0832	Belongs to the urease beta subunit family
OCW38_RS11670	COG0831	urea catabolic process
OCW38_RS11710	COG3706	GGDEF domain
OCW38_RS11715	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OCW38_RS11720	COG1160	GTP binding
OCW38_RS11725	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCW38_RS11730	COG2976	Protein conserved in bacteria
OCW38_RS11735	COG0124	histidyl-tRNA synthetase
OCW38_RS11740	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OCW38_RS11745	COG1426	Protein conserved in bacteria
OCW38_RS11750	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OCW38_RS11755	COG0105	UTP biosynthetic process
OCW38_RS11760	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OCW38_RS11765	COG2975	iron-sulfur cluster assembly
OCW38_RS11775	COG0443	Heat shock 70 kDa protein
OCW38_RS11780	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OCW38_RS11790	COG0822	iron-sulfur transferase activity
OCW38_RS11795	COG1104	cysteine desulfurase activity
OCW38_RS11800	COG1959	2 iron, 2 sulfur cluster binding
OCW38_RS11805	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
OCW38_RS11810	COG0483	inositol monophosphate 1-phosphatase activity
OCW38_RS11815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OCW38_RS11820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OCW38_RS11825	COG1862	Preprotein translocase
OCW38_RS11830	COG0343	queuine tRNA-ribosyltransferase activity
OCW38_RS11835	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OCW38_RS11840	COG0517	IMP dehydrogenase activity
OCW38_RS11845	COG0840	transmembrane signaling receptor activity
OCW38_RS11850	COG0583	DNA-binding transcription factor activity
OCW38_RS11855	COG0450	alkyl hydroperoxide reductase
OCW38_RS11860	COG3142	Participates in the control of copper homeostasis
OCW38_RS11880	COG0704	Plays a role in the regulation of phosphate uptake
OCW38_RS11885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OCW38_RS11890	COG0581	inorganic phosphate transmembrane transporter activity
OCW38_RS11900	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OCW38_RS11905	COG0248	Ppx GppA phosphatase
OCW38_RS11915	COG5002	protein histidine kinase activity
OCW38_RS11920	COG0745	RESPONSE REGULATOR receiver
OCW38_RS11925	COG2974	May be involved in recombination
OCW38_RS11930	COG0826	peptidase U32
OCW38_RS11935	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OCW38_RS11945	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
OCW38_RS11990	COG0564	pseudouridine synthase activity
OCW38_RS11995	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCW38_RS12000	COG0741	lytic transglycosylase activity
OCW38_RS12005	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OCW38_RS12010	COG1605	Chorismate mutase
OCW38_RS12010	COG0077	Prephenate dehydratase
OCW38_RS12015	COG5001	Diguanylate cyclase
OCW38_RS12020	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
OCW38_RS12025	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
OCW38_RS12035	COG0488	(ABC) transporter
OCW38_RS12045	COG0739	heme binding
OCW38_RS12050	COG0287	Prephenate dehydrogenase
OCW38_RS12050	COG1605	Chorismate mutase
OCW38_RS12055	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OCW38_RS12065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OCW38_RS12070	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OCW38_RS12080	COG1966	Carbon starvation protein
OCW38_RS12085	COG3275	phosphorelay sensor kinase activity
OCW38_RS12090	COG3279	Response regulator of the LytR AlgR family
OCW38_RS12095	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OCW38_RS12100	COG1047	Peptidyl-prolyl cis-trans
OCW38_RS12110	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OCW38_RS12115	COG0196	riboflavin kinase activity
OCW38_RS12120	COG0728	peptidoglycan biosynthetic process
OCW38_RS12125	COG0268	Binds directly to 16S ribosomal RNA
OCW38_RS12130	COG0640	Transcriptional regulator
OCW38_RS12135	COG0583	DNA-binding transcription factor activity
OCW38_RS12140	COG1283	sodium-dependent phosphate transmembrane transporter activity
OCW38_RS12145	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OCW38_RS12150	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OCW38_RS12155	COG0730	response to heat
OCW38_RS12165	COG0494	nUDIX hydrolase
OCW38_RS12185	COG3829	transcription factor binding
OCW38_RS12185	COG3290	protein histidine kinase activity
OCW38_RS12190	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OCW38_RS12200	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OCW38_RS12205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OCW38_RS12210	COG4974	Belongs to the 'phage' integrase family
OCW38_RS12215	COG0716	FMN binding
OCW38_RS12225	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OCW38_RS12230	COG0513	Belongs to the DEAD box helicase family
OCW38_RS12235	COG3022	response to hydroperoxide
OCW38_RS12240	COG1115	amino acid carrier protein
OCW38_RS12255	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OCW38_RS12265	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
OCW38_RS12270	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OCW38_RS12275	COG0083	homoserine kinase activity
OCW38_RS12290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OCW38_RS12300	COG0745	RESPONSE REGULATOR receiver
OCW38_RS12310	COG2198	Histidine kinase
OCW38_RS12310	COG0784	Response regulator, receiver
OCW38_RS12310	COG5002	protein histidine kinase activity
OCW38_RS12315	COG5001	Diguanylate cyclase
OCW38_RS12315	COG4251	negative regulation of phosphorylation
OCW38_RS12315	COG3706	GGDEF domain
OCW38_RS12315	COG2203	Gaf domain
OCW38_RS12320	COG1242	4 iron, 4 sulfur cluster binding
OCW38_RS12325	COG0069	glutamate synthase activity
OCW38_RS12325	COG0070	glutamate synthase
OCW38_RS12325	COG0067	glutamate synthase
OCW38_RS12335	COG0067	glutamate synthase
OCW38_RS12335	COG0069	glutamate synthase activity
OCW38_RS12335	COG0070	glutamate synthase
OCW38_RS12340	COG0493	'glutamate synthase
OCW38_RS12350	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OCW38_RS12365	COG2860	membrane
OCW38_RS12370	COG0583	DNA-binding transcription factor activity
OCW38_RS12375	COG0730	response to heat
OCW38_RS12380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OCW38_RS12385	COG0505	Belongs to the CarA family
OCW38_RS12390	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OCW38_RS12395	COG0494	nUDIX hydrolase
OCW38_RS12400	COG0653	protein targeting
OCW38_RS12405	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
OCW38_RS12410	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OCW38_RS12415	COG0849	cell division
OCW38_RS12420	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OCW38_RS12425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OCW38_RS12430	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OCW38_RS12435	COG0772	Belongs to the SEDS family
OCW38_RS12440	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OCW38_RS12445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OCW38_RS12450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OCW38_RS12455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OCW38_RS12460	COG0768	penicillin binding
OCW38_RS12465	COG3116	cell division
OCW38_RS12470	COG0275	rRNA processing
OCW38_RS12480	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OCW38_RS12495	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OCW38_RS12500	COG2823	Periplasmic or secreted lipoprotein
OCW38_RS12505	COG2969	positive regulation of protein catabolic process
OCW38_RS12510	COG0625	glutathione transferase activity
OCW38_RS12515	COG2857	Cytochrome c1
OCW38_RS12520	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OCW38_RS12525	COG0723	plastoquinol--plastocyanin reductase activity
OCW38_RS12530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OCW38_RS12535	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OCW38_RS12540	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OCW38_RS12545	COG3105	Protein conserved in bacteria
OCW38_RS12550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OCW38_RS12555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OCW38_RS12560	COG3385	transposase activity
OCW38_RS12575	COG3150	esterase
OCW38_RS12585	COG3151	Protein conserved in bacteria
OCW38_RS12590	COG0494	nUDIX hydrolase
OCW38_RS12595	COG1538	Outer membrane efflux protein
OCW38_RS12600	COG3385	transposase activity
OCW38_RS12605	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OCW38_RS12605	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OCW38_RS12610	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OCW38_RS12620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OCW38_RS12625	COG3025	triphosphatase activity
OCW38_RS12630	COG1392	Phosphate transport regulator
OCW38_RS12635	COG0306	phosphate transporter
OCW38_RS12640	COG4991	sh3 domain protein
OCW38_RS12650	COG3409	Peptidoglycan-binding domain 1 protein
OCW38_RS12650	COG3267	Type II secretory pathway component ExeA
OCW38_RS12660	COG1968	undecaprenyl-diphosphatase activity
OCW38_RS12665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OCW38_RS12670	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OCW38_RS12675	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OCW38_RS12680	COG0596	Alpha beta hydrolase
OCW38_RS12685	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OCW38_RS12690	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OCW38_RS12695	COG1610	YqeY-like protein
OCW38_RS12715	COG2873	o-acetylhomoserine
OCW38_RS12720	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OCW38_RS12725	COG1349	DNA-binding transcription factor activity
OCW38_RS12730	COG0469	pyruvate kinase activity
OCW38_RS12740	COG3706	GGDEF domain
OCW38_RS12750	COG0028	Belongs to the TPP enzyme family
OCW38_RS12755	COG1022	Amp-dependent synthetase and ligase
OCW38_RS12790	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OCW38_RS12795	COG0473	3-isopropylmalate dehydrogenase activity
OCW38_RS12805	COG0066	3-isopropylmalate dehydratase activity
OCW38_RS12820	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OCW38_RS12825	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OCW38_RS12830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OCW38_RS12835	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OCW38_RS12840	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OCW38_RS12845	COG2967	ApaG domain
OCW38_RS12855	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OCW38_RS12860	COG3610	response to peptide
OCW38_RS12865	COG2966	Psort location CytoplasmicMembrane, score
OCW38_RS12870	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OCW38_RS12875	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OCW38_RS12880	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OCW38_RS12885	COG0142	geranyltranstransferase activity
OCW38_RS12895	COG0039	L-malate dehydrogenase activity
OCW38_RS12900	COG1438	arginine binding
OCW38_RS12915	COG0589	response to stress
OCW38_RS12920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OCW38_RS12935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OCW38_RS12940	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OCW38_RS12945	COG0312	modulator of DNA gyrase
OCW38_RS12950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OCW38_RS12965	COG0424	maF-like protein
OCW38_RS12970	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OCW38_RS12975	COG1792	Involved in formation and maintenance of cell shape
OCW38_RS12980	COG1077	Cell shape determining protein MreB Mrl
OCW38_RS13010	COG2165	general secretion pathway protein
OCW38_RS13015	COG2165	general secretion pathway protein
OCW38_RS13025	COG1459	type II secretion system
OCW38_RS13030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OCW38_RS13040	COG3267	Type II secretory pathway component ExeA
OCW38_RS13040	COG3409	Peptidoglycan-binding domain 1 protein
OCW38_RS13065	COG2200	EAL domain
OCW38_RS13065	COG2199	diguanylate cyclase activity
OCW38_RS13070	COG0629	single-stranded DNA binding
OCW38_RS13075	COG2197	response regulator
OCW38_RS13085	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OCW38_RS13095	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OCW38_RS13100	COG0527	aspartate kinase activity
OCW38_RS13105	COG0646	methionine synthase
OCW38_RS13105	COG1410	methionine synthase
OCW38_RS13185	COG3385	transposase activity
OCW38_RS13190	COG0175	sulfate reduction
OCW38_RS13195	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OCW38_RS13200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OCW38_RS13225	COG0735	belongs to the Fur family
OCW38_RS13235	COG0166	Belongs to the GPI family
OCW38_RS13255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OCW38_RS13270	COG0359	binds to the 23S rRNA
OCW38_RS13285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OCW38_RS13290	COG0557	exoribonuclease II activity
OCW38_RS13295	COG0402	S-adenosylhomocysteine deaminase activity
OCW38_RS13300	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
OCW38_RS13305	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OCW38_RS13310	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
OCW38_RS13315	COG0330	HflC and HflK could
OCW38_RS13320	COG0330	HflC and HflK could
OCW38_RS13325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OCW38_RS13330	COG1923	regulation of RNA biosynthetic process
OCW38_RS13335	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OCW38_RS13340	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OCW38_RS13345	COG0860	N-Acetylmuramoyl-L-alanine amidase
OCW38_RS13350	COG0802	atpase or kinase
OCW38_RS13360	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OCW38_RS13455	COG1162	GTPase activity
OCW38_RS13465	COG0471	metal ion transport
OCW38_RS13465	COG0490	domain, Protein
OCW38_RS13475	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OCW38_RS13480	COG1053	succinate dehydrogenase
OCW38_RS13485	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OCW38_RS13490	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
OCW38_RS13505	COG2885	chlorophyll binding
OCW38_RS13525	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OCW38_RS13530	COG1509	lysine 2,3-aminomutase activity
OCW38_RS13535	COG1285	pathogenesis
OCW38_RS13545	COG0840	transmembrane signaling receptor activity
OCW38_RS13560	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OCW38_RS13565	COG0534	Mate efflux family protein
OCW38_RS13585	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OCW38_RS13590	COG5001	Diguanylate cyclase
OCW38_RS13590	COG3300	MHYT domain
OCW38_RS13595	COG2197	response regulator
OCW38_RS13600	COG4251	negative regulation of phosphorylation
OCW38_RS13605	COG2199	diguanylate cyclase activity
OCW38_RS13605	COG2203	Gaf domain
OCW38_RS13615	COG5001	Diguanylate cyclase
OCW38_RS13615	COG4251	negative regulation of phosphorylation
OCW38_RS13615	COG3706	GGDEF domain
OCW38_RS13615	COG2203	Gaf domain
OCW38_RS13620	COG2199	diguanylate cyclase activity
OCW38_RS13625	COG2199	diguanylate cyclase activity
OCW38_RS13635	COG0840	transmembrane signaling receptor activity
OCW38_RS13640	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OCW38_RS13655	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OCW38_RS13665	COG5001	Diguanylate cyclase
OCW38_RS13665	COG4251	negative regulation of phosphorylation
OCW38_RS13665	COG3706	GGDEF domain
OCW38_RS13665	COG2203	Gaf domain
OCW38_RS13690	COG2015	COG2015, Alkyl sulfatase and related hydrolases
OCW38_RS13730	COG4453	Protein conserved in bacteria
OCW38_RS13810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OCW38_RS13920	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OCW38_RS13925	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OCW38_RS13925	COG0517	IMP dehydrogenase activity
OCW38_RS13935	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OCW38_RS13940	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OCW38_RS13945	COG3562	capsule polysaccharide
OCW38_RS13950	COG0438	transferase activity, transferring glycosyl groups
OCW38_RS13960	COG1216	Glycosyl transferase, family 2
OCW38_RS14035	COG1596	polysaccharide export
OCW38_RS14040	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCW38_RS14060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OCW38_RS14065	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OCW38_RS14075	COG1045	serine acetyltransferase
OCW38_RS14080	COG4942	peptidase
OCW38_RS14100	COG1560	Kdo2-lipid A biosynthetic process
OCW38_RS14115	COG0438	transferase activity, transferring glycosyl groups
OCW38_RS14125	COG0463	Glycosyl transferase, family 2
OCW38_RS14135	COG1519	Transferase
OCW38_RS14140	COG3642	lipopolysaccharide core region biosynthetic process
OCW38_RS14145	COG0859	PFAM glycosyl transferase family 9
OCW38_RS14165	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OCW38_RS14175	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OCW38_RS14180	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OCW38_RS14185	COG0675	Transposase, IS605 OrfB family
OCW38_RS14190	COG2003	Belongs to the UPF0758 family
OCW38_RS14200	COG1309	transcriptional regulator
OCW38_RS14205	COG1560	Kdo2-lipid A biosynthetic process
OCW38_RS14210	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OCW38_RS14215	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OCW38_RS14220	COG1561	YicC-like family, N-terminal region
OCW38_RS14230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OCW38_RS14260	COG1278	Cold shock
OCW38_RS14270	COG2252	PERMEase
OCW38_RS14275	COG0194	GDP metabolic process
OCW38_RS14280	COG1758	RNA polymerase activity
OCW38_RS14285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OCW38_RS14290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OCW38_RS14305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OCW38_RS14310	COG2183	response to ionizing radiation
OCW38_RS14320	COG0596	Alpha beta hydrolase
OCW38_RS14325	COG1040	competence protein
OCW38_RS14330	COG0316	Belongs to the HesB IscA family
OCW38_RS14330	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OCW38_RS14335	COG0494	nUDIX hydrolase
OCW38_RS14340	COG1218	3'(2'),5'-bisphosphate nucleotidase
OCW38_RS14355	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
OCW38_RS14360	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
OCW38_RS14365	COG3156	type II secretion system protein K
OCW38_RS14370	COG4795	General secretion pathway protein
OCW38_RS14375	COG2165	general secretion pathway protein
OCW38_RS14380	COG2165	general secretion pathway protein
OCW38_RS14385	COG2165	general secretion pathway protein
OCW38_RS14390	COG1459	type II secretion system
OCW38_RS14395	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OCW38_RS14405	COG3031	protein transport across the cell outer membrane
OCW38_RS14410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OCW38_RS14420	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OCW38_RS14430	COG0456	acetyltransferase
OCW38_RS14435	COG1490	D-aminoacyl-tRNA deacylase activity
OCW38_RS14440	COG1295	ribonuclease BN
OCW38_RS14455	COG1217	gtp-binding protein TYPA
OCW38_RS14460	COG0174	glutamine synthetase
OCW38_RS14470	COG3852	Histidine kinase
OCW38_RS14475	COG2204	response regulator
OCW38_RS14495	COG3078	GTPase activator activity
OCW38_RS14520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCW38_RS14520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCW38_RS14535	COG0084	hydrolase, TatD family'
OCW38_RS14540	COG0805	protein transport
OCW38_RS14545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OCW38_RS14550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OCW38_RS14555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OCW38_RS14560	COG3165	ubiquinone biosynthetic process from chorismate
OCW38_RS14565	COG2226	methyltransferase
OCW38_RS14570	COG1322	Protein conserved in bacteria
OCW38_RS14580	COG2081	HI0933 family
OCW38_RS14590	COG1528	Iron-storage protein
OCW38_RS14595	COG0589	response to stress
OCW38_RS14610	COG0742	ribosomal rna small subunit methyltransferase
OCW38_RS14615	COG5001	Diguanylate cyclase
OCW38_RS14615	COG5002	protein histidine kinase activity
OCW38_RS14620	COG1522	sequence-specific DNA binding
OCW38_RS14625	COG0339	signal peptide processing
OCW38_RS14630	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OCW38_RS14635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCW38_RS14645	COG1805	sodium ion transport
OCW38_RS14655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCW38_RS14660	COG0601	transmembrane transport
OCW38_RS14710	COG1309	transcriptional regulator
OCW38_RS14715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCW38_RS14720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCW38_RS14725	COG2960	long-chain fatty acid transporting porin activity
OCW38_RS14730	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OCW38_RS14735	COG0583	DNA-binding transcription factor activity
OCW38_RS14780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OCW38_RS14790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OCW38_RS14795	COG0408	coproporphyrinogen oxidase activity
OCW38_RS14800	COG0009	L-threonylcarbamoyladenylate synthase
OCW38_RS14805	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OCW38_RS14810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OCW38_RS14815	COG0551	DNA topoisomerase type I activity
OCW38_RS14820	COG2922	Belongs to the Smg family
OCW38_RS14825	COG0758	DNA mediated transformation
OCW38_RS14840	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OCW38_RS14845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OCW38_RS14845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OCW38_RS14850	COG0569	domain protein
OCW38_RS14855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OCW38_RS14865	COG1272	protein, Hemolysin III
OCW38_RS14870	COG4326	sporulation control protein
OCW38_RS14880	COG3084	Protein conserved in bacteria
OCW38_RS14890	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OCW38_RS14895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OCW38_RS14905	COG0606	chelatase, subunit chli
OCW38_RS14915	COG3978	acetolactate synthase activity
OCW38_RS14920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OCW38_RS14925	COG0129	dihydroxy-acid dehydratase activity
OCW38_RS14935	COG0583	DNA-binding transcription factor activity
OCW38_RS14940	COG2814	Major facilitator Superfamily
OCW38_RS14950	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OCW38_RS14955	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OCW38_RS14960	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OCW38_RS14965	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OCW38_RS14970	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OCW38_RS14975	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OCW38_RS14990	COG3312	ion transport
OCW38_RS14995	COG1475	DNA binding
OCW38_RS15000	COG1192	Involved in chromosome partitioning
OCW38_RS15005	COG0357	Ribosomal RNA small subunit methyltransferase G
OCW38_RS15010	COG0445	tRNA wobble uridine modification
OCW38_RS15015	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OCW38_RS15025	COG0706	membrane insertase activity
OCW38_RS15030	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OCW38_RS15035	COG0594	ribonuclease P activity
OCW38_RS15040	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OCW38_RS15045	COG1126	abc transporter atp-binding protein
OCW38_RS15060	COG3459	Glycosyltransferase 36 associated
OCW38_RS15075	COG1609	Transcriptional regulator
OCW38_RS15080	COG4172	Belongs to the ABC transporter superfamily
OCW38_RS15090	COG1067	ATP-dependent peptidase activity
OCW38_RS15140	COG1846	Transcriptional regulator
OCW38_RS15145	COG2259	Doxx family
OCW38_RS15155	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OCW38_RS15160	COG3960	tartronate-semialdehyde synthase activity
OCW38_RS15165	COG3622	Belongs to the hyi family
OCW38_RS15170	COG2084	Dehydrogenase
OCW38_RS15185	COG0402	S-adenosylhomocysteine deaminase activity
OCW38_RS15210	COG2252	PERMEase
OCW38_RS15230	COG4266	Belongs to the allantoicase family
OCW38_RS15235	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OCW38_RS15255	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OCW38_RS15270	COG0789	Transcriptional regulator
OCW38_RS15275	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OCW38_RS15285	COG0402	S-adenosylhomocysteine deaminase activity
OCW38_RS15295	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OCW38_RS15305	COG2186	Transcriptional regulator
OCW38_RS15315	COG1418	mRNA catabolic process
OCW38_RS15320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OCW38_RS15325	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
OCW38_RS15365	COG1263	PTS System
OCW38_RS15365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCW38_RS15370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCW38_RS15375	COG1621	beta-fructofuranosidase activity
OCW38_RS15385	COG0583	DNA-binding transcription factor activity
OCW38_RS15390	COG0415	Belongs to the DNA photolyase family
OCW38_RS15395	COG3284	Transcriptional regulator
OCW38_RS15400	COG1012	belongs to the aldehyde dehydrogenase family
OCW38_RS15415	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OCW38_RS15420	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OCW38_RS15440	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OCW38_RS15445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OCW38_RS15450	COG0302	gtp cyclohydrolase
OCW38_RS15460	COG0431	NADPH-dependent FMN reductase
OCW38_RS15465	COG0697	spore germination
OCW38_RS15480	COG0641	radical SAM
OCW38_RS15490	COG3119	arylsulfatase activity
OCW38_RS15510	COG4166	transmembrane transport
OCW38_RS15550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCW38_RS15550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCW38_RS15550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCW38_RS15555	COG2207	Transcriptional regulator
OCW38_RS15570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCW38_RS15575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCW38_RS15590	COG0840	transmembrane signaling receptor activity
OCW38_RS15600	COG1012	belongs to the aldehyde dehydrogenase family
OCW38_RS15610	COG0814	amino acid
OCW38_RS15615	COG2814	Major facilitator Superfamily
OCW38_RS15630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OCW38_RS15645	COG0840	transmembrane signaling receptor activity
OCW38_RS15655	COG0583	DNA-binding transcription factor activity
OCW38_RS15675	COG0583	DNA-binding transcription factor activity
OCW38_RS15685	COG4948	Mandelate Racemase Muconate Lactonizing
OCW38_RS15710	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
OCW38_RS15715	COG3639	organic phosphonate transmembrane transporter activity
OCW38_RS15720	COG3639	organic phosphonate transmembrane transporter activity
OCW38_RS15735	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OCW38_RS15740	COG3047	cAMP biosynthetic process
OCW38_RS15750	COG4221	oxidoreductase activity
OCW38_RS15755	COG0583	DNA-binding transcription factor activity
OCW38_RS15760	COG1733	regulation of RNA biosynthetic process
OCW38_RS15765	COG1028	Short-chain dehydrogenase reductase Sdr
OCW38_RS15775	COG2910	NAD(P)H-binding
OCW38_RS15780	COG0583	DNA-binding transcription factor activity
OCW38_RS15790	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OCW38_RS15820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OCW38_RS15825	COG1595	DNA-templated transcription, initiation
OCW38_RS15840	COG1901	pseudouridine methyltransferase
OCW38_RS15905	COG4977	sequence-specific DNA binding
OCW38_RS15925	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OCW38_RS15930	COG2999	glutathione oxidoreductase activity
OCW38_RS15940	COG0673	inositol 2-dehydrogenase activity
OCW38_RS15960	COG0584	glycerophosphoryl diester phosphodiesterase
OCW38_RS15965	COG3842	ATPase activity
OCW38_RS15970	COG0395	ABC-type sugar transport system, permease component
OCW38_RS15995	COG4067	protein conserved in archaea
OCW38_RS15995	COG0189	ligase activity
OCW38_RS16000	COG0189	ligase activity
OCW38_RS16005	COG4166	transmembrane transport
OCW38_RS16045	COG2814	Major facilitator Superfamily
OCW38_RS16055	COG0564	pseudouridine synthase activity
OCW38_RS16065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OCW38_RS16065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OCW38_RS16085	COG1131	(ABC) transporter
OCW38_RS16095	COG5001	Diguanylate cyclase
OCW38_RS16100	COG5001	Diguanylate cyclase
OCW38_RS16110	COG0745	RESPONSE REGULATOR receiver
OCW38_RS16115	COG2205	protein histidine kinase activity
OCW38_RS16120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCW38_RS16125	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OCW38_RS16130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCW38_RS16135	COG3037	sugar-specific permease SgaT UlaA
OCW38_RS16155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OCW38_RS16180	COG0745	RESPONSE REGULATOR receiver
OCW38_RS16185	COG0642	Histidine kinase
OCW38_RS16190	COG4106	trans-aconitate 2-methyltransferase activity
OCW38_RS16205	COG0513	Belongs to the DEAD box helicase family
OCW38_RS16220	COG3706	GGDEF domain
OCW38_RS16225	COG1278	Cold shock
OCW38_RS16230	COG0402	S-adenosylhomocysteine deaminase activity
OCW38_RS16235	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OCW38_RS16255	COG4413	Urea transporter
OCW38_RS16270	COG0531	amino acid
OCW38_RS16285	COG1280	lysine exporter protein (LysE YggA)
OCW38_RS16300	COG1151	hydroxylamine reductase activity
OCW38_RS16305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OCW38_RS16330	COG2926	Belongs to the UPF0265 family
OCW38_RS16340	COG3132	Protein of unknown function, DUF480
OCW38_RS16345	COG2827	Endonuclease containing a URI domain
OCW38_RS16375	COG0443	Heat shock 70 kDa protein
OCW38_RS16385	COG0179	Fumarylacetoacetate (FAA) hydrolase
OCW38_RS16390	COG1280	lysine exporter protein (LysE YggA)
OCW38_RS16395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OCW38_RS16400	COG1565	acr, cog1565
OCW38_RS16400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OCW38_RS16405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OCW38_RS16415	COG1845	cytochrome c oxidase, subunit III
OCW38_RS16435	COG1612	heme a metabolic process
OCW38_RS16440	COG0109	protoheme IX farnesyltransferase activity
OCW38_RS16455	COG3530	Putative quorum-sensing-regulated virulence factor
OCW38_RS16470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OCW38_RS16475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OCW38_RS16485	COG0668	transmembrane transport
OCW38_RS16490	COG0569	domain protein
OCW38_RS16495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OCW38_RS16500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCW38_RS16500	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCW38_RS16505	COG1765	OsmC-like protein
OCW38_RS16510	COG2885	chlorophyll binding
OCW38_RS16520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OCW38_RS16530	COG1840	ABC-type Fe3 transport system, periplasmic component
OCW38_RS16535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OCW38_RS16540	COG3842	ATPase activity
OCW38_RS16560	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OCW38_RS16570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OCW38_RS16575	COG3265	gluconokinase activity
OCW38_RS16580	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OCW38_RS16585	COG1609	Transcriptional regulator
OCW38_RS16590	COG2375	cellular response to nickel ion
OCW38_RS16595	COG3104	oligopeptide transport
OCW38_RS16600	COG1760	l-serine dehydratase
OCW38_RS16615	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OCW38_RS16620	COG1132	(ABC) transporter
OCW38_RS16625	COG1132	(ABC) transporter
OCW38_RS16650	COG0739	heme binding
OCW38_RS16655	COG0393	Putative heavy-metal-binding
OCW38_RS16670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OCW38_RS16675	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OCW38_RS16695	COG0346	lactoylglutathione lyase activity
OCW38_RS16705	COG0156	8-amino-7-oxononanoate synthase activity
OCW38_RS16710	COG1063	alcohol dehydrogenase
OCW38_RS16720	COG2249	NAD(P)H dehydrogenase (quinone) activity
OCW38_RS16745	COG1454	alcohol dehydrogenase
OCW38_RS16755	COG1011	Hydrolase
OCW38_RS16780	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCW38_RS16785	COG1328	CTP reductase activity
OCW38_RS16790	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OCW38_RS16795	COG0583	DNA-binding transcription factor activity
OCW38_RS16815	COG1289	transmembrane transporter activity
OCW38_RS16820	COG0210	DNA helicase
OCW38_RS16830	COG1803	Methylglyoxal synthase
OCW38_RS16835	COG1879	ABC-type sugar transport system periplasmic component
OCW38_RS16890	COG0625	glutathione transferase activity
OCW38_RS16900	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OCW38_RS16900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCW38_RS16900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCW38_RS16905	COG1105	Belongs to the carbohydrate kinase PfkB family
OCW38_RS16910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCW38_RS16910	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCW38_RS16915	COG1609	Transcriptional regulator
OCW38_RS16920	COG0515	serine threonine protein kinase
OCW38_RS16920	COG2815	serine threonine protein kinase
OCW38_RS16925	COG2223	nitrite transmembrane transporter activity
OCW38_RS16935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OCW38_RS16940	COG0243	molybdopterin cofactor binding
OCW38_RS17020	COG0784	Response regulator, receiver
OCW38_RS17020	COG2205	protein histidine kinase activity
OCW38_RS17025	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OCW38_RS17040	COG1609	Transcriptional regulator
OCW38_RS17045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCW38_RS17050	COG1879	ABC-type sugar transport system periplasmic component
OCW38_RS17055	COG1172	Belongs to the binding-protein-dependent transport system permease family
OCW38_RS17060	COG1129	ABC transporter
OCW38_RS17065	COG1869	D-ribose catabolic process
OCW38_RS17080	COG4166	transmembrane transport
OCW38_RS17085	COG4174	ABC transporter (Permease)
OCW38_RS17090	COG4239	(ABC) transporter, permease
OCW38_RS17095	COG4172	Belongs to the ABC transporter superfamily
OCW38_RS17105	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OCW38_RS17125	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OCW38_RS17175	COG0583	DNA-binding transcription factor activity
OCW38_RS17185	COG1012	belongs to the aldehyde dehydrogenase family
OCW38_RS17195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OCW38_RS17235	COG3278	Belongs to the heme-copper respiratory oxidase family
OCW38_RS17245	COG2199	diguanylate cyclase activity
OCW38_RS17250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OCW38_RS17250	COG3153	acetyltransferase
OCW38_RS17265	COG5001	Diguanylate cyclase
OCW38_RS17265	COG3300	MHYT domain
OCW38_RS17275	COG0384	phenazine biosynthesis protein PhzF
OCW38_RS17300	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
OCW38_RS17315	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OCW38_RS17325	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OCW38_RS17330	COG3119	arylsulfatase activity
OCW38_RS17335	COG3119	arylsulfatase activity
OCW38_RS17345	COG0714	Associated with various cellular activities
OCW38_RS17375	COG0583	DNA-binding transcription factor activity
OCW38_RS17380	COG1597	lipid kinase activity
OCW38_RS17395	COG0641	radical SAM
OCW38_RS17405	COG0405	Gamma-glutamyltransferase
OCW38_RS17410	COG0840	transmembrane signaling receptor activity
OCW38_RS17460	COG1132	(ABC) transporter
OCW38_RS17465	COG1538	Outer membrane efflux protein
OCW38_RS17470	COG0784	Response regulator, receiver
OCW38_RS17470	COG2205	protein histidine kinase activity
OCW38_RS17475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCW38_RS17510	COG0840	transmembrane signaling receptor activity
OCW38_RS17545	COG1881	PFAM PEBP family protein
OCW38_RS17555	COG2807	transmembrane transport
OCW38_RS17560	COG3048	D-serine ammonia-lyase activity
OCW38_RS17590	COG1280	lysine exporter protein (LysE YggA)
OCW38_RS17615	COG0534	Mate efflux family protein
OCW38_RS17635	COG0509	glycine decarboxylation via glycine cleavage system
OCW38_RS17675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OCW38_RS17680	COG3706	GGDEF domain
OCW38_RS17685	COG2759	Belongs to the formate--tetrahydrofolate ligase family
OCW38_RS17690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCW38_RS17705	COG3437	response regulator, receiver
OCW38_RS17705	COG0784	Response regulator, receiver
OCW38_RS17710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OCW38_RS17720	COG0814	amino acid
OCW38_RS17730	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
OCW38_RS17735	COG0513	Belongs to the DEAD box helicase family
OCW38_RS17760	COG2200	EAL domain
OCW38_RS17775	COG3038	cytochrome b561
OCW38_RS17780	COG2353	YceI-like domain
OCW38_RS17785	COG2116	formate transmembrane transporter activity
OCW38_RS17790	COG0583	DNA-binding transcription factor activity
OCW38_RS17800	COG3593	DNA synthesis involved in DNA repair
OCW38_RS17805	COG0737	Belongs to the 5'-nucleotidase family
OCW38_RS17810	COG0861	Integral membrane protein TerC family
OCW38_RS17825	COG0513	Belongs to the DEAD box helicase family
OCW38_RS17830	COG0729	surface antigen
OCW38_RS17835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OCW38_RS17840	COG2272	Belongs to the type-B carboxylesterase lipase family
OCW38_RS17855	COG1566	PFAM secretion protein HlyD family protein
OCW38_RS17865	COG2985	domain, Protein
OCW38_RS17875	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
OCW38_RS17890	COG0583	DNA-binding transcription factor activity
OCW38_RS17905	COG2267	carboxylic ester hydrolase activity
OCW38_RS17910	COG2067	long-chain fatty acid transport protein
OCW38_RS17920	COG0501	Belongs to the peptidase M48B family
OCW38_RS17925	COG2050	protein possibly involved in aromatic compounds catabolism
OCW38_RS17935	COG4533	DNA binding
OCW38_RS17965	COG0768	penicillin binding
OCW38_RS17975	COG5001	Diguanylate cyclase
OCW38_RS17975	COG1716	ATPase activity
OCW38_RS17980	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OCW38_RS17990	COG4181	ATPase activity
OCW38_RS17995	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OCW38_RS18005	COG1984	allophanate hydrolase subunit 2
OCW38_RS18010	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OCW38_RS18025	COG4771	TonB-dependent receptor
OCW38_RS18025	COG1629	transport
OCW38_RS18030	COG0583	DNA-binding transcription factor activity
OCW38_RS18035	COG1042	CoA-binding domain protein
OCW38_RS18035	COG0045	succinate-CoA ligase (ADP-forming) activity
OCW38_RS18035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCW38_RS18040	COG3266	domain, Protein
OCW38_RS18045	COG1181	Belongs to the D-alanine--D-alanine ligase family
OCW38_RS18060	COG0023	Translation Initiation Factor
OCW38_RS18120	COG3706	GGDEF domain
OCW38_RS18125	COG3140	Belongs to the UPF0181 family
OCW38_RS18150	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
OCW38_RS18155	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
OCW38_RS18170	COG3706	GGDEF domain
OCW38_RS18180	COG5001	Diguanylate cyclase
OCW38_RS18180	COG4251	negative regulation of phosphorylation
OCW38_RS18180	COG3706	GGDEF domain
OCW38_RS18180	COG2203	Gaf domain
OCW38_RS18190	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OCW38_RS18195	COG4149	molybdate abc transporter
OCW38_RS18200	COG0725	ABC transporter, periplasmic molybdate-binding protein
OCW38_RS18220	COG0488	(ABC) transporter
OCW38_RS18225	COG4067	protein conserved in archaea
OCW38_RS18225	COG0189	ligase activity
OCW38_RS18235	COG0602	queuosine metabolic process
OCW38_RS18240	COG1328	CTP reductase activity
OCW38_RS18270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OCW38_RS18275	COG3118	belongs to the thioredoxin family
OCW38_RS18285	COG0318	PFAM AMP-dependent synthetase and ligase
OCW38_RS18315	COG0534	Mate efflux family protein
OCW38_RS18340	COG1321	iron dependent repressor
OCW38_RS18340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OCW38_RS18345	COG1121	(ABC) transporter
OCW38_RS18350	COG0803	Belongs to the bacterial solute-binding protein 9 family
OCW38_RS18395	COG0848	biopolymer transport protein
OCW38_RS18400	COG0811	peptide transport
OCW38_RS18405	COG0811	peptide transport
OCW38_RS18420	COG1301	dicarboxylic acid transport
OCW38_RS18425	COG2205	protein histidine kinase activity
OCW38_RS18430	COG0745	RESPONSE REGULATOR receiver
OCW38_RS18445	COG1648	precorrin-2 dehydrogenase activity
OCW38_RS18445	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OCW38_RS18450	COG2116	formate transmembrane transporter activity
OCW38_RS18460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OCW38_RS18510	COG0840	transmembrane signaling receptor activity
OCW38_RS18535	COG2425	protein containing a von Willebrand factor type A (vWA) domain
OCW38_RS18545	COG0494	nUDIX hydrolase
OCW38_RS18550	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
OCW38_RS18605	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OCW38_RS18610	COG2199	diguanylate cyclase activity
OCW38_RS18610	COG2203	Gaf domain
OCW38_RS18615	COG1214	PFAM Peptidase M22, glycoprotease
OCW38_RS18615	COG0456	acetyltransferase
OCW38_RS18635	COG1929	Belongs to the glycerate kinase type-1 family
OCW38_RS18640	COG0383	alpha-mannosidase activity
OCW38_RS18645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCW38_RS18645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCW38_RS18645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCW38_RS18650	COG2188	Transcriptional regulator
OCW38_RS18675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCW38_RS18680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCW38_RS18685	COG2067	long-chain fatty acid transport protein
OCW38_RS18690	COG2267	carboxylic ester hydrolase activity
OCW38_RS18705	COG3069	C4-dicarboxylate transmembrane transporter activity
OCW38_RS18710	COG2197	response regulator
OCW38_RS18715	COG3850	Histidine kinase
OCW38_RS18720	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OCW38_RS18720	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
OCW38_RS18730	COG0243	molybdopterin cofactor binding
OCW38_RS18760	COG0183	Belongs to the thiolase family
OCW38_RS18775	COG4974	Belongs to the 'phage' integrase family
OCW38_RS18820	COG0745	RESPONSE REGULATOR receiver
OCW38_RS18855	COG0513	Belongs to the DEAD box helicase family
OCW38_RS18860	COG0523	cobalamin synthesis protein
OCW38_RS18865	COG0038	chloride channel
OCW38_RS18875	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OCW38_RS18885	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OCW38_RS18890	COG1175	transmembrane transport
OCW38_RS18900	COG1609	Transcriptional regulator
OCW38_RS18905	COG1017	nitric oxide dioxygenase activity
OCW38_RS18905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OCW38_RS18910	COG3604	Transcriptional regulator
OCW38_RS18930	COG0545	Peptidyl-prolyl cis-trans isomerase
OCW38_RS18935	COG1309	transcriptional regulator
OCW38_RS18940	COG2130	NADP-dependent
OCW38_RS18950	COG0564	pseudouridine synthase activity
OCW38_RS18960	COG1686	Belongs to the peptidase S11 family
OCW38_RS18975	COG2199	diguanylate cyclase activity
OCW38_RS18985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OCW38_RS19005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCW38_RS19025	COG2207	Transcriptional regulator
OCW38_RS19030	COG1979	alcohol dehydrogenase
OCW38_RS19035	COG1126	abc transporter atp-binding protein
OCW38_RS19040	COG0765	amino acid transport
OCW38_RS19050	COG0765	amino acid transport
OCW38_RS19075	COG2824	Alkylphosphonate utilization operon protein PhnA
OCW38_RS19095	COG5297	Belongs to the glycosyl hydrolase family 6
OCW38_RS19095	COG2273	Hydrolase Family 16
OCW38_RS19115	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCW38_RS19140	COG0446	pyridine nucleotide-disulphide oxidoreductase
OCW38_RS19140	COG1902	pentaerythritol trinitrate reductase activity
OCW38_RS19155	COG1024	Enoyl-CoA hydratase
OCW38_RS19185	COG1120	ATPase activity
OCW38_RS19195	COG2133	pyrroloquinoline quinone binding
OCW38_RS19200	COG1278	Cold shock
OCW38_RS19205	COG4681	YaeQ
OCW38_RS19215	COG0302	gtp cyclohydrolase
OCW38_RS19245	COG2897	thiosulfate sulfurtransferase activity
OCW38_RS19250	COG3706	GGDEF domain
OCW38_RS19250	COG2203	Gaf domain
OCW38_RS19250	COG4251	negative regulation of phosphorylation
OCW38_RS19250	COG5001	Diguanylate cyclase
OCW38_RS19265	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OCW38_RS19270	COG0840	transmembrane signaling receptor activity
OCW38_RS19275	COG1522	sequence-specific DNA binding
OCW38_RS19290	COG5433	transposase activity
OCW38_RS19300	COG2814	Major facilitator Superfamily
OCW38_RS19305	COG0583	DNA-binding transcription factor activity
OCW38_RS19310	COG2205	protein histidine kinase activity
OCW38_RS19310	COG2198	Histidine kinase
OCW38_RS19310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCW38_RS19310	COG0784	Response regulator, receiver
OCW38_RS19315	COG3437	response regulator, receiver
OCW38_RS19320	COG4604	ABC transporter, ATP-binding protein
OCW38_RS19325	COG4605	iron ion homeostasis
OCW38_RS19330	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCW38_RS19360	COG0628	permease
OCW38_RS19370	COG1566	PFAM secretion protein HlyD family protein
OCW38_RS19385	COG0583	DNA-binding transcription factor activity
OCW38_RS19400	COG0840	transmembrane signaling receptor activity
OCW38_RS19405	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OCW38_RS19410	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OCW38_RS19415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OCW38_RS19420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCW38_RS19425	COG1116	anion transmembrane transporter activity
OCW38_RS19430	COG0351	phosphomethylpyrimidine kinase
OCW38_RS19435	COG0697	spore germination
OCW38_RS19525	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OCW38_RS19565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OCW38_RS19575	COG1196	nuclear chromosome segregation
OCW38_RS19585	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OCW38_RS19650	COG0516	GMP reductase activity
OCW38_RS19675	COG0534	Mate efflux family protein
OCW38_RS19680	COG0583	DNA-binding transcription factor activity
OCW38_RS19685	COG0366	Alpha amylase catalytic
OCW38_RS19700	COG0583	DNA-binding transcription factor activity
OCW38_RS19710	COG0697	spore germination
OCW38_RS19715	COG1120	ATPase activity
OCW38_RS19720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCW38_RS19725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCW38_RS19730	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OCW38_RS19735	COG4772	TonB-dependent receptor
OCW38_RS19755	COG0604	alcohol dehydrogenase
OCW38_RS19770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OCW38_RS19775	COG0513	Belongs to the DEAD box helicase family
OCW38_RS19780	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
OCW38_RS19795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OCW38_RS19810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCW38_RS19830	COG2195	Cleaves the N-terminal amino acid of tripeptides
OCW38_RS19840	COG0667	Aldo Keto reductase
OCW38_RS19845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OCW38_RS19850	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OCW38_RS19855	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
OCW38_RS19860	COG0513	Belongs to the DEAD box helicase family
OCW38_RS19870	COG2176	DNA-directed DNA polymerase activity
OCW38_RS19885	COG0513	Belongs to the DEAD box helicase family
OCW38_RS19890	COG4989	oxidoreductase activity
OCW38_RS19910	COG1538	Outer membrane efflux protein
OCW38_RS19915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCW38_RS19960	COG0668	transmembrane transport
OCW38_RS19970	COG4232	protein-disulfide reductase activity
OCW38_RS19975	COG3118	belongs to the thioredoxin family
OCW38_RS19995	COG0697	spore germination
OCW38_RS20015	COG2814	Major facilitator Superfamily
OCW38_RS20020	COG0583	DNA-binding transcription factor activity
OCW38_RS20025	COG5001	Diguanylate cyclase
OCW38_RS20030	COG0739	heme binding
OCW38_RS20055	COG3314	Sporulation integral membrane protein YlbJ
OCW38_RS20065	COG0366	Alpha amylase catalytic
OCW38_RS20070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OCW38_RS20075	COG0835	chemotaxis
OCW38_RS20075	COG0784	Response regulator, receiver
OCW38_RS20080	COG2096	Adenosyltransferase
OCW38_RS20085	COG0748	coenzyme F420 binding
OCW38_RS20090	COG3721	Heme iron utilization protein
OCW38_RS20100	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
OCW38_RS20105	COG0811	peptide transport
OCW38_RS20110	COG0848	biopolymer transport protein
OCW38_RS20120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCW38_RS20125	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OCW38_RS20170	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OCW38_RS20175	COG3217	Mosc domain protein beta barrel domain protein
OCW38_RS20175	COG0633	Ferredoxin
OCW38_RS20185	COG0418	dihydroorotase activity
OCW38_RS20190	COG2354	Protein conserved in bacteria
OCW38_RS20200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OCW38_RS20215	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OCW38_RS20215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OCW38_RS20220	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OCW38_RS20225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OCW38_RS20230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OCW38_RS20260	COG0730	response to heat
OCW38_RS20265	COG0280	phosphate acetyltransferase
OCW38_RS20270	COG1414	Transcriptional regulator
OCW38_RS20275	COG1012	belongs to the aldehyde dehydrogenase family
OCW38_RS20305	COG4934	collagen metabolic process
OCW38_RS20345	COG1904	glucuronate isomerase
OCW38_RS20350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCW38_RS20370	COG1028	Short-chain dehydrogenase reductase Sdr
OCW38_RS20405	COG0697	spore germination
OCW38_RS20410	COG0698	ribose 5-phosphate isomerase
OCW38_RS20425	COG1136	(ABC) transporter
OCW38_RS20430	COG0577	efflux transmembrane transporter activity
OCW38_RS20440	COG0745	RESPONSE REGULATOR receiver
OCW38_RS20445	COG2205	protein histidine kinase activity
OCW38_RS20450	COG1136	(ABC) transporter
OCW38_RS20450	COG0577	efflux transmembrane transporter activity
OCW38_RS20455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCW38_RS20460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCW38_RS20465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCW38_RS20480	COG2814	Major facilitator Superfamily
OCW38_RS20510	COG3833	ABC-type maltose transport systems, permease component
OCW38_RS20515	COG1175	transmembrane transport
OCW38_RS20525	COG3842	ATPase activity
OCW38_RS20535	COG0840	transmembrane signaling receptor activity
OCW38_RS20540	COG0714	Associated with various cellular activities
OCW38_RS20555	COG2304	oxidoreductase activity
OCW38_RS20560	COG2304	oxidoreductase activity
OCW38_RS20570	COG3706	GGDEF domain
OCW38_RS20575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OCW38_RS20580	COG0581	inorganic phosphate transmembrane transporter activity
OCW38_RS20585	COG0573	inorganic phosphate transmembrane transporter activity
OCW38_RS20625	COG4771	TonB-dependent receptor
OCW38_RS20640	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OCW38_RS20645	COG3240	lipase activity
OCW38_RS20650	COG0513	Belongs to the DEAD box helicase family
OCW38_RS20660	COG1388	LysM domain
OCW38_RS20660	COG1376	ErfK ybiS ycfS ynhG family protein
OCW38_RS20665	COG0813	purine-nucleoside phosphorylase activity
OCW38_RS20695	COG1566	PFAM secretion protein HlyD family protein
OCW38_RS20700	COG4720	Psort location CytoplasmicMembrane, score
OCW38_RS20705	COG1122	ATPase activity
OCW38_RS20720	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OCW38_RS20725	COG1640	4-alpha-glucanotransferase
OCW38_RS20730	COG0058	SHG alpha-glucan phosphorylase activity
OCW38_RS20750	COG1999	signal sequence binding
OCW38_RS20760	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
OCW38_RS20800	COG3258	Cytochrome c
OCW38_RS20840	COG4580	involved in the transport of maltose and maltodextrins
OCW38_RS20860	COG0204	Acyl-transferase
OCW38_RS20865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OCW38_RS20875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OCW38_RS20880	COG4667	esterase of the alpha-beta hydrolase superfamily
OCW38_RS20885	COG0753	catalase activity
OCW38_RS20890	COG1929	Belongs to the glycerate kinase type-1 family
OCW38_RS20895	COG2610	gluconate transmembrane transporter activity
OCW38_RS20900	COG3622	Belongs to the hyi family
OCW38_RS20905	COG0235	Class ii aldolase
OCW38_RS20910	COG3395	kinase activity
OCW38_RS20915	COG2084	Dehydrogenase
OCW38_RS20920	COG1349	DNA-binding transcription factor activity
OCW38_RS20945	COG0583	DNA-binding transcription factor activity
OCW38_RS20950	COG3214	Protein conserved in bacteria
OCW38_RS20965	COG0561	phosphatase activity
OCW38_RS20970	COG1309	transcriptional regulator
OCW38_RS20985	COG0798	PFAM Bile acid sodium symporter
OCW38_RS20990	COG0583	DNA-binding transcription factor activity
OCW38_RS21000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OCW38_RS21005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OCW38_RS21010	COG1349	DNA-binding transcription factor activity
OCW38_RS21015	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OCW38_RS21020	COG1028	Short-chain dehydrogenase reductase Sdr
OCW38_RS21025	COG0583	DNA-binding transcription factor activity
OCW38_RS21035	COG1794	racemase activity, acting on amino acids and derivatives
OCW38_RS21050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OCW38_RS21070	COG0583	DNA-binding transcription factor activity
OCW38_RS21075	COG2814	Major facilitator Superfamily
OCW38_RS21115	COG0110	maltose O-acetyltransferase activity
OCW38_RS21120	COG1609	Transcriptional regulator
OCW38_RS21125	COG2723	6-phospho-beta-galactosidase activity
OCW38_RS21135	COG0346	lactoylglutathione lyase activity
OCW38_RS21150	COG2015	COG2015, Alkyl sulfatase and related hydrolases
OCW38_RS21155	COG0300	oxidoreductase activity
OCW38_RS21190	COG3321	synthase
OCW38_RS21190	COG1028	Short-chain dehydrogenase reductase Sdr
OCW38_RS21190	COG0604	alcohol dehydrogenase
OCW38_RS21210	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OCW38_RS21215	COG0110	maltose O-acetyltransferase activity
OCW38_RS21225	COG0628	permease
OCW38_RS21255	COG0668	transmembrane transport
OCW38_RS21260	COG1803	Methylglyoxal synthase
OCW38_RS21260	COG1597	lipid kinase activity
OCW38_RS21290	COG0527	aspartate kinase activity
OCW38_RS21300	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OCW38_RS21305	COG0456	acetyltransferase
OCW38_RS21325	COG1309	transcriptional regulator
OCW38_RS21330	COG0641	radical SAM
OCW38_RS21360	COG1846	Transcriptional regulator
OCW38_RS21365	COG0517	IMP dehydrogenase activity
OCW38_RS21365	COG4175	Glycine betaine
OCW38_RS21385	COG1012	belongs to the aldehyde dehydrogenase family
OCW38_RS21390	COG1309	transcriptional regulator
OCW38_RS21400	COG0745	RESPONSE REGULATOR receiver
OCW38_RS21405	COG2205	protein histidine kinase activity
OCW38_RS21425	COG0579	oxidoreductase
OCW38_RS21440	COG2204	response regulator
OCW38_RS21445	COG3852	Histidine kinase
OCW38_RS21475	COG2194	sulfuric ester hydrolase activity
OCW38_RS21500	COG1132	(ABC) transporter
OCW38_RS21505	COG4399	Belongs to the UPF0754 family
OCW38_RS21525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCW38_RS21560	COG0259	pyridoxamine-phosphate oxidase activity
OCW38_RS21600	COG1444	tRNA N-acetyltransferase activity
OCW38_RS21635	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OCW38_RS21635	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
OCW38_RS21650	COG4221	oxidoreductase activity
OCW38_RS21665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OCW38_RS21680	COG0765	amino acid transport
OCW38_RS21715	COG3842	ATPase activity
OCW38_RS21725	COG0745	RESPONSE REGULATOR receiver
OCW38_RS21730	COG2205	protein histidine kinase activity
OCW38_RS21750	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OCW38_RS21760	COG0625	glutathione transferase activity
OCW38_RS21780	COG4221	oxidoreductase activity
OCW38_RS21780	COG3321	synthase
OCW38_RS21780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OCW38_RS21780	COG0604	alcohol dehydrogenase
OCW38_RS21785	COG0583	DNA-binding transcription factor activity
OCW38_RS21795	COG0625	glutathione transferase activity
OCW38_RS21805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OCW38_RS21810	COG3186	Phenylalanine-4-hydroxylase
OCW38_RS21825	COG0217	transcriptional regulatory protein
OCW38_RS21840	COG2084	Dehydrogenase
OCW38_RS21845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OCW38_RS21865	COG0583	DNA-binding transcription factor activity
OCW38_RS21890	COG4591	ABC-type transport system involved in lipoprotein release permease component
OCW38_RS21905	COG3275	phosphorelay sensor kinase activity
OCW38_RS21910	COG3279	Response regulator of the LytR AlgR family
OCW38_RS21925	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OCW38_RS21930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OCW38_RS21950	COG2814	Major facilitator Superfamily
OCW38_RS21955	COG1028	Short-chain dehydrogenase reductase Sdr
OCW38_RS21975	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OCW38_RS21985	COG0724	RNA recognition motif
OCW38_RS21990	COG4221	oxidoreductase activity
OCW38_RS22015	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OCW38_RS22040	COG0415	Belongs to the DNA photolyase family
OCW38_RS22050	COG3806	Anti-sigma factor
OCW38_RS22055	COG1595	DNA-templated transcription, initiation
OCW38_RS22065	COG1942	4-Oxalocrotonate Tautomerase
OCW38_RS22080	COG0786	glutamate:sodium symporter activity
OCW38_RS22105	COG2213	PTS system mannitol-specific
OCW38_RS22105	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCW38_RS22110	COG0246	Mannitol dehydrogenase
OCW38_RS22115	COG3722	fumarate hydratase activity
OCW38_RS22120	COG0363	glucosamine-6-phosphate deaminase activity
OCW38_RS22140	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OCW38_RS22155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OCW38_RS22165	COG3788	relative of glutathione S-transferase, MAPEG superfamily
OCW38_RS22205	COG0596	Alpha beta hydrolase
OCW38_RS22220	COG3123	guanosine phosphorylase activity
OCW38_RS22225	COG1741	Belongs to the pirin family
OCW38_RS22255	COG2197	response regulator
OCW38_RS22260	COG3851	Histidine kinase
OCW38_RS22265	COG2271	Major facilitator Superfamily
OCW38_RS22270	COG1482	cell wall glycoprotein biosynthetic process
OCW38_RS22285	COG1054	Belongs to the UPF0176 family
OCW38_RS22300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OCW38_RS22305	COG2207	Transcriptional regulator
OCW38_RS22305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OCW38_RS22310	COG0534	Mate efflux family protein
OCW38_RS22320	COG4172	Belongs to the ABC transporter superfamily
OCW38_RS22325	COG0747	negative chemotaxis
OCW38_RS22345	COG1304	FMN binding
OCW38_RS22350	COG1620	l-lactate permease
OCW38_RS22355	COG0583	DNA-binding transcription factor activity
OCW38_RS22360	COG1505	serine-type exopeptidase activity
OCW38_RS22390	COG0395	ABC-type sugar transport system, permease component
OCW38_RS22395	COG2723	6-phospho-beta-galactosidase activity
OCW38_RS22400	COG3842	ATPase activity
OCW38_RS22410	COG1028	Short-chain dehydrogenase reductase Sdr
OCW38_RS22430	COG0840	transmembrane signaling receptor activity
OCW38_RS22455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCW38_RS22460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCW38_RS22465	COG1904	glucuronate isomerase
OCW38_RS22475	COG1192	Involved in chromosome partitioning
OCW38_RS22495	COG0800	Aldolase
OCW38_RS22500	COG2723	6-phospho-beta-galactosidase activity
OCW38_RS22505	COG1263	PTS System
OCW38_RS22505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCW38_RS22510	COG3265	gluconokinase activity
OCW38_RS22515	COG0129	dihydroxy-acid dehydratase activity
OCW38_RS22520	COG1609	Transcriptional regulator
OCW38_RS22555	COG0583	DNA-binding transcription factor activity
OCW38_RS22630	COG2017	converts alpha-aldose to the beta-anomer
OCW38_RS22635	COG1472	Belongs to the glycosyl hydrolase 3 family
OCW38_RS22640	COG2115	Belongs to the xylose isomerase family
OCW38_RS22645	COG3842	ATPase activity
OCW38_RS22650	COG1609	Transcriptional regulator
OCW38_RS22655	COG3693	PFAM glycoside hydrolase, family 10
OCW38_RS22660	COG4580	involved in the transport of maltose and maltodextrins
OCW38_RS22665	COG3842	ATPase activity
OCW38_RS22675	COG1175	transmembrane transport
OCW38_RS22680	COG0395	ABC-type sugar transport system, permease component
OCW38_RS22695	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OCW38_RS22710	COG2115	Belongs to the xylose isomerase family
OCW38_RS22715	COG2211	Major facilitator Superfamily
OCW38_RS22725	COG1472	Belongs to the glycosyl hydrolase 3 family
OCW38_RS22730	COG4213	ABC transporter substrate-binding protein
OCW38_RS22735	COG1129	ABC transporter
OCW38_RS22740	COG4214	carbohydrate transport
OCW38_RS22745	COG1609	Transcriptional regulator
OCW38_RS22745	COG2207	Transcriptional regulator
OCW38_RS22750	COG1070	Carbohydrate kinase
OCW38_RS22760	COG0673	inositol 2-dehydrogenase activity
OCW38_RS22770	COG3344	reverse transcriptase
OCW38_RS22810	COG2205	protein histidine kinase activity
OCW38_RS22815	COG0745	RESPONSE REGULATOR receiver
OCW38_RS22825	COG0569	domain protein
OCW38_RS22830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OCW38_RS22850	COG5001	Diguanylate cyclase
OCW38_RS22875	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OCW38_RS22900	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OCW38_RS22935	COG0800	Aldolase