locus-tag	class	description
AL468_RS00010	COG0366	Alpha amylase catalytic
AL468_RS00015	COG0789	Transcriptional regulator
AL468_RS00030	COG4934	collagen metabolic process
AL468_RS00040	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL468_RS00045	COG0583	DNA-binding transcription factor activity
AL468_RS00070	COG2610	gluconate transmembrane transporter activity
AL468_RS00075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL468_RS00080	COG3622	Belongs to the hyi family
AL468_RS00085	COG0235	Class ii aldolase
AL468_RS00090	COG3395	kinase activity
AL468_RS00095	COG2084	Dehydrogenase
AL468_RS00100	COG1349	DNA-binding transcription factor activity
AL468_RS00110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL468_RS00115	COG0784	Response regulator, receiver
AL468_RS00115	COG0835	chemotaxis
AL468_RS00125	COG0748	coenzyme F420 binding
AL468_RS00130	COG3721	Heme iron utilization protein
AL468_RS00140	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL468_RS00145	COG0811	peptide transport
AL468_RS00150	COG0848	biopolymer transport protein
AL468_RS00160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL468_RS00165	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL468_RS00205	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL468_RS00210	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AL468_RS00215	COG0633	Ferredoxin
AL468_RS00215	COG3217	Mosc domain protein beta barrel domain protein
AL468_RS00215	COG3217	Mosc domain protein beta barrel domain protein
AL468_RS00215	COG0633	Ferredoxin
AL468_RS00220	COG0401	homolog of Blt101
AL468_RS00230	COG0418	dihydroorotase activity
AL468_RS00235	COG2354	Protein conserved in bacteria
AL468_RS00265	COG3833	ABC-type maltose transport systems, permease component
AL468_RS00270	COG1175	transmembrane transport
AL468_RS00280	COG3842	ATPase activity
AL468_RS00285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL468_RS00300	COG3206	protein involved in exopolysaccharide biosynthesis
AL468_RS00300	COG0489	protein tyrosine kinase activity
AL468_RS00345	COG1309	transcriptional regulator
AL468_RS00350	COG2130	NADP-dependent
AL468_RS00360	COG0753	catalase activity
AL468_RS00365	COG2084	Dehydrogenase
AL468_RS00370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL468_RS00375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL468_RS00385	COG2207	Transcriptional regulator
AL468_RS00390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL468_RS00390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL468_RS00390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL468_RS00420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL468_RS00425	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AL468_RS00430	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL468_RS00440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL468_RS00445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL468_RS00450	COG1012	belongs to the aldehyde dehydrogenase family
AL468_RS00465	COG0583	DNA-binding transcription factor activity
AL468_RS00470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL468_RS00475	COG0569	domain protein
AL468_RS00480	COG0745	RESPONSE REGULATOR receiver
AL468_RS00485	COG2205	protein histidine kinase activity
AL468_RS00485	COG2205	protein histidine kinase activity
AL468_RS00490	COG1132	(ABC) transporter
AL468_RS00495	COG4774	siderophore transport
AL468_RS00500	COG1120	ATPase activity
AL468_RS00505	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AL468_RS00540	COG2197	response regulator
AL468_RS00550	COG0840	transmembrane signaling receptor activity
AL468_RS00560	COG0714	Associated with various cellular activities
AL468_RS00575	COG2304	oxidoreductase activity
AL468_RS00580	COG2304	oxidoreductase activity
AL468_RS00595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL468_RS00600	COG0581	inorganic phosphate transmembrane transporter activity
AL468_RS00605	COG0573	inorganic phosphate transmembrane transporter activity
AL468_RS00635	COG4771	TonB-dependent receptor
AL468_RS00640	COG1770	oligopeptidase
AL468_RS00645	COG0513	Belongs to the DEAD box helicase family
AL468_RS00655	COG1388	LysM domain
AL468_RS00655	COG1376	ErfK ybiS ycfS ynhG family protein
AL468_RS00660	COG0415	Belongs to the DNA photolyase family
AL468_RS00665	COG0789	Transcriptional regulator
AL468_RS00670	COG3272	Protein of unknown function (DUF1722)
AL468_RS00675	COG0813	purine-nucleoside phosphorylase activity
AL468_RS00690	COG3706	GGDEF domain
AL468_RS00700	COG1566	PFAM secretion protein HlyD family protein
AL468_RS00705	COG4720	Psort location CytoplasmicMembrane, score
AL468_RS00710	COG1122	ATPase activity
AL468_RS00730	COG0348	domain, Protein
AL468_RS00735	COG0437	4 iron, 4 sulfur cluster binding
AL468_RS00740	COG1247	-acetyltransferase
AL468_RS00760	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL468_RS00765	COG0840	transmembrane signaling receptor activity
AL468_RS00770	COG1067	ATP-dependent peptidase activity
AL468_RS00780	COG4172	Belongs to the ABC transporter superfamily
AL468_RS00785	COG1505	serine-type exopeptidase activity
AL468_RS00790	COG0583	DNA-binding transcription factor activity
AL468_RS00795	COG1620	l-lactate permease
AL468_RS00800	COG1304	FMN binding
AL468_RS00810	COG0668	transmembrane transport
AL468_RS00820	COG1063	alcohol dehydrogenase
AL468_RS00825	COG0156	8-amino-7-oxononanoate synthase activity
AL468_RS00830	COG5001	Diguanylate cyclase
AL468_RS00830	COG3300	MHYT domain
AL468_RS00835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL468_RS00855	COG0745	RESPONSE REGULATOR receiver
AL468_RS00880	COG0346	lactoylglutathione lyase activity
AL468_RS00935	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL468_RS00975	COG1987	bacterial-type flagellum assembly
AL468_RS00985	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL468_RS01000	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL468_RS01010	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL468_RS01015	COG1516	flagellar protein fliS
AL468_RS01030	COG1580	Controls the rotational direction of flagella during chemotaxis
AL468_RS01035	COG1191	sigma factor activity
AL468_RS01040	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AL468_RS01045	COG1360	Flagellar Motor Protein
AL468_RS01100	COG1882	Formate acetyltransferase
AL468_RS01105	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL468_RS01110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL468_RS01120	COG0454	-acetyltransferase
AL468_RS01130	COG2814	Major facilitator Superfamily
AL468_RS01175	COG0628	permease
AL468_RS01180	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL468_RS01195	COG4628	conserved protein (DUF2132)
AL468_RS01200	COG0583	DNA-binding transcription factor activity
AL468_RS01225	COG1686	Belongs to the peptidase S11 family
AL468_RS01250	COG0415	Belongs to the DNA photolyase family
AL468_RS01255	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL468_RS01260	COG3397	chitin binding
AL468_RS01265	COG4667	esterase of the alpha-beta hydrolase superfamily
AL468_RS01270	COG2095	MarC family integral membrane protein
AL468_RS01285	COG1596	polysaccharide export
AL468_RS01305	COG1301	dicarboxylic acid transport
AL468_RS01310	COG3339	Conserved Protein
AL468_RS01315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL468_RS01320	COG0700	Nucleoside recognition
AL468_RS01325	COG3366	ferrous iron transmembrane transporter activity
AL468_RS01340	COG0366	Alpha amylase catalytic
AL468_RS01345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL468_RS01350	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL468_RS01355	COG1640	4-alpha-glucanotransferase
AL468_RS01360	COG0058	SHG alpha-glucan phosphorylase activity
AL468_RS01370	COG2909	trisaccharide binding
AL468_RS01385	COG1999	signal sequence binding
AL468_RS01390	COG1263	PTS System
AL468_RS01390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL468_RS01395	COG1162	GTPase activity
AL468_RS01400	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AL468_RS01405	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AL468_RS01415	COG0531	amino acid
AL468_RS01420	COG1982	Orn Lys Arg decarboxylase major
AL468_RS01440	COG2356	endonuclease I
AL468_RS01460	COG4580	involved in the transport of maltose and maltodextrins
AL468_RS01505	COG0739	heme binding
AL468_RS01515	COG0612	Peptidase, M16
AL468_RS01520	COG0840	transmembrane signaling receptor activity
AL468_RS01525	COG1120	ATPase activity
AL468_RS01530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL468_RS01535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL468_RS01540	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AL468_RS01545	COG4772	TonB-dependent receptor
AL468_RS01570	COG4264	IucA IucC family
AL468_RS01575	COG0019	diaminopimelate decarboxylase activity
AL468_RS01580	COG1653	transport
AL468_RS01590	COG0745	RESPONSE REGULATOR receiver
AL468_RS01615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL468_RS01625	COG0463	Glycosyl transferase, family 2
AL468_RS01645	COG1136	(ABC) transporter
AL468_RS01665	COG1764	response to oxidative stress
AL468_RS01670	COG1846	Transcriptional regulator
AL468_RS01680	COG3634	alkyl hydroperoxide reductase activity
AL468_RS01705	COG1595	DNA-templated transcription, initiation
AL468_RS01725	COG2258	MOSC domain
AL468_RS01750	COG2207	Transcriptional regulator
AL468_RS01760	COG1132	(ABC) transporter
AL468_RS01795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL468_RS01820	COG0259	pyridoxamine-phosphate oxidase activity
AL468_RS01875	COG4166	transmembrane transport
AL468_RS01895	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL468_RS01900	COG1263	PTS System
AL468_RS01900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL468_RS01905	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL468_RS01910	COG3340	Belongs to the peptidase S51 family
AL468_RS01930	COG1444	tRNA N-acetyltransferase activity
AL468_RS01955	COG4608	Belongs to the ABC transporter superfamily
AL468_RS01960	COG0444	Belongs to the ABC transporter superfamily
AL468_RS01970	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AL468_RS01970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL468_RS01995	COG0772	Belongs to the SEDS family
AL468_RS02005	COG1136	(ABC) transporter
AL468_RS02025	COG3275	phosphorelay sensor kinase activity
AL468_RS02030	COG3279	Response regulator of the LytR AlgR family
AL468_RS02040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL468_RS02060	COG0786	glutamate:sodium symporter activity
AL468_RS02070	COG1131	(ABC) transporter
AL468_RS02075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL468_RS02080	COG0786	glutamate:sodium symporter activity
AL468_RS02090	COG0363	glucosamine-6-phosphate deaminase activity
AL468_RS02110	COG1741	Belongs to the pirin family
AL468_RS02115	COG2259	Doxx family
AL468_RS02125	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL468_RS02140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AL468_RS02165	COG0596	Alpha beta hydrolase
AL468_RS02180	COG3123	guanosine phosphorylase activity
AL468_RS02195	COG0534	Mate efflux family protein
AL468_RS02200	COG0564	pseudouridine synthase activity
AL468_RS02215	COG0583	DNA-binding transcription factor activity
AL468_RS02220	COG0561	phosphatase activity
AL468_RS02230	COG2199	diguanylate cyclase activity
AL468_RS02245	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AL468_RS02250	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AL468_RS02255	COG0583	DNA-binding transcription factor activity
AL468_RS02260	COG2375	cellular response to nickel ion
AL468_RS02295	COG1357	PFAM Pentapeptide repeats (8 copies)
AL468_RS02300	COG3047	cAMP biosynthetic process
AL468_RS02330	COG3408	Glycogen debranching enzyme
AL468_RS02330	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AL468_RS02335	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AL468_RS02345	COG0583	DNA-binding transcription factor activity
AL468_RS02390	COG2200	EAL domain
AL468_RS02425	COG1278	Cold shock
AL468_RS02445	COG0330	HflC and HflK could
AL468_RS02455	COG1278	Cold shock
AL468_RS02460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL468_RS02465	COG0569	domain protein
AL468_RS02470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL468_RS02475	COG0745	RESPONSE REGULATOR receiver
AL468_RS02480	COG2205	protein histidine kinase activity
AL468_RS02485	COG0668	transmembrane transport
AL468_RS02490	COG1477	protein flavinylation
AL468_RS02500	COG1968	undecaprenyl-diphosphatase activity
AL468_RS02550	COG1028	Short-chain dehydrogenase reductase Sdr
AL468_RS02580	COG4977	sequence-specific DNA binding
AL468_RS02710	COG2814	Major facilitator Superfamily
AL468_RS02740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL468_RS02750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL468_RS02750	COG1028	Short-chain dehydrogenase reductase Sdr
AL468_RS02750	COG3321	synthase
AL468_RS02750	COG4221	oxidoreductase activity
AL468_RS02765	COG2267	carboxylic ester hydrolase activity
AL468_RS02770	COG2977	Belongs to the P-Pant transferase superfamily
AL468_RS02795	COG4974	Belongs to the 'phage' integrase family
AL468_RS02800	COG0583	DNA-binding transcription factor activity
AL468_RS02815	COG0546	phosphoglycolate phosphatase activity
AL468_RS02840	COG3835	regulator
AL468_RS02845	COG2610	gluconate transmembrane transporter activity
AL468_RS02850	COG1929	Belongs to the glycerate kinase type-1 family
AL468_RS02855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL468_RS02875	COG0456	acetyltransferase
AL468_RS02890	COG1028	Short-chain dehydrogenase reductase Sdr
AL468_RS02895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL468_RS02900	COG3005	denitrification pathway
AL468_RS02905	COG0243	molybdopterin cofactor binding
AL468_RS02915	COG0352	thiamine-phosphate diphosphorylase activity
AL468_RS02920	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AL468_RS02925	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL468_RS02930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL468_RS02935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL468_RS02940	COG1116	anion transmembrane transporter activity
AL468_RS02945	COG0351	phosphomethylpyrimidine kinase
AL468_RS02950	COG0312	modulator of DNA gyrase
AL468_RS02955	COG0312	modulator of DNA gyrase
AL468_RS02960	COG1901	pseudouridine methyltransferase
AL468_RS03020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL468_RS03030	COG0584	glycerophosphoryl diester phosphodiesterase
AL468_RS03035	COG0039	L-malate dehydrogenase activity
AL468_RS03040	COG0745	RESPONSE REGULATOR receiver
AL468_RS03060	COG0811	peptide transport
AL468_RS03065	COG0811	peptide transport
AL468_RS03070	COG0848	biopolymer transport protein
AL468_RS03115	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL468_RS03120	COG1121	(ABC) transporter
AL468_RS03125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL468_RS03140	COG1770	oligopeptidase
AL468_RS03145	COG2814	Major facilitator Superfamily
AL468_RS03150	COG0010	Belongs to the arginase family
AL468_RS03155	COG1166	arginine decarboxylase activity
AL468_RS03165	COG4067	protein conserved in archaea
AL468_RS03165	COG0189	ligase activity
AL468_RS03170	COG0189	ligase activity
AL468_RS03175	COG0583	DNA-binding transcription factor activity
AL468_RS03210	COG4191	Histidine kinase
AL468_RS03215	COG2204	response regulator
AL468_RS03220	COG3706	GGDEF domain
AL468_RS03225	COG1114	Component of the transport system for branched-chain amino acids
AL468_RS03245	COG0579	oxidoreductase
AL468_RS03270	COG1294	oxidase, subunit
AL468_RS03275	COG1271	oxidase subunit
AL468_RS03285	COG3033	Beta-eliminating lyase
AL468_RS03305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL468_RS03320	COG3706	GGDEF domain
AL468_RS03335	COG3706	GGDEF domain
AL468_RS03340	COG0415	Belongs to the DNA photolyase family
AL468_RS03345	COG3046	protein related to deoxyribodipyrimidine photolyase
AL468_RS03360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL468_RS03360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL468_RS03365	COG1765	OsmC-like protein
AL468_RS03370	COG0110	maltose O-acetyltransferase activity
AL468_RS03410	COG1011	Hydrolase
AL468_RS03425	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL468_RS03435	COG2067	long-chain fatty acid transport protein
AL468_RS03445	COG3240	lipase activity
AL468_RS03475	COG1609	Transcriptional regulator
AL468_RS03480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL468_RS03490	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL468_RS03495	COG1840	ABC-type Fe3 transport system, periplasmic component
AL468_RS03500	COG3842	ATPase activity
AL468_RS03525	COG2990	Protein conserved in bacteria
AL468_RS03535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL468_RS03540	COG2866	Carboxypeptidase
AL468_RS03550	COG0583	DNA-binding transcription factor activity
AL468_RS03570	COG3104	oligopeptide transport
AL468_RS03575	COG1760	l-serine dehydratase
AL468_RS03595	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL468_RS03600	COG0741	lytic transglycosylase activity
AL468_RS03620	COG1815	bacterial-type flagellum-dependent cell motility
AL468_RS03625	COG1558	bacterial-type flagellum-dependent cell motility
AL468_RS03630	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL468_RS03635	COG1749	Flagellar hook protein flgE
AL468_RS03640	COG4787	bacterial-type flagellum-dependent cell motility
AL468_RS03645	COG4786	Flagellar basal body rod
AL468_RS03650	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL468_RS03655	COG1706	bacterial-type flagellum-dependent cell motility
AL468_RS03665	COG4786	Flagellar basal body rod
AL468_RS03665	COG1256	bacterial-type flagellum assembly
AL468_RS03670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL468_RS03690	COG1304	FMN binding
AL468_RS03705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL468_RS03710	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL468_RS03715	COG0459	protein refolding
AL468_RS03745	COG1309	transcriptional regulator
AL468_RS03750	COG2207	Transcriptional regulator
AL468_RS03755	COG4303	Ethanolamine ammonia lyase large subunit
AL468_RS03760	COG4302	ethanolamine ammonia-lyase activity
AL468_RS03765	COG0531	amino acid
AL468_RS03770	COG2070	2-Nitropropane dioxygenase
AL468_RS03775	COG3537	Alpha-1,2-mannosidase
AL468_RS03780	COG3537	Alpha-1,2-mannosidase
AL468_RS03790	COG3537	Alpha-1,2-mannosidase
AL468_RS03795	COG3537	Alpha-1,2-mannosidase
AL468_RS03800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL468_RS03815	COG0346	lactoylglutathione lyase activity
AL468_RS03820	COG1349	DNA-binding transcription factor activity
AL468_RS03830	COG1335	isochorismatase
AL468_RS03840	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL468_RS03865	COG0583	DNA-binding transcription factor activity
AL468_RS03880	COG3713	MltA-interacting MipA family protein
AL468_RS03885	COG3015	lipoprotein NlpE involved in copper resistance
AL468_RS03890	COG3448	diguanylate cyclase activity
AL468_RS03890	COG4175	Glycine betaine
AL468_RS03895	COG4176	ABC-type proline glycine betaine transport system permease component
AL468_RS03905	COG1342	Belongs to the UPF0251 family
AL468_RS03940	COG4948	Mandelate Racemase Muconate Lactonizing
AL468_RS03950	COG0583	DNA-binding transcription factor activity
AL468_RS03990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL468_RS04020	COG3842	ATPase activity
AL468_RS04050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL468_RS04075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL468_RS04090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL468_RS04095	COG2197	response regulator
AL468_RS04110	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL468_RS04115	COG0252	asparaginase activity
AL468_RS04125	COG0583	DNA-binding transcription factor activity
AL468_RS04135	COG1280	lysine exporter protein (LysE YggA)
AL468_RS04140	COG3122	Protein conserved in bacteria
AL468_RS04150	COG2423	ornithine cyclodeaminase activity
AL468_RS04155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL468_RS04160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL468_RS04165	COG1012	belongs to the aldehyde dehydrogenase family
AL468_RS04170	COG1522	sequence-specific DNA binding
AL468_RS04175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL468_RS04180	COG3608	succinylglutamate desuccinylase aspartoacylase
AL468_RS04185	COG0006	proline dipeptidase activity
AL468_RS04190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL468_RS04195	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL468_RS04200	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL468_RS04205	COG2207	Transcriptional regulator
AL468_RS04210	COG1028	Short-chain dehydrogenase reductase Sdr
AL468_RS04220	COG1063	alcohol dehydrogenase
AL468_RS04225	COG1902	pentaerythritol trinitrate reductase activity
AL468_RS04240	COG0583	DNA-binding transcription factor activity
AL468_RS04250	COG0513	Belongs to the DEAD box helicase family
AL468_RS04290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL468_RS04295	COG2207	Transcriptional regulator
AL468_RS04295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL468_RS04315	COG3746	phosphate-selective porin O and P
AL468_RS04330	COG1028	Short-chain dehydrogenase reductase Sdr
AL468_RS04355	COG1263	PTS System
AL468_RS04355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL468_RS04360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL468_RS04365	COG1621	beta-fructofuranosidase activity
AL468_RS04375	COG0625	glutathione transferase activity
AL468_RS04385	COG1686	Belongs to the peptidase S11 family
AL468_RS04395	COG0678	peroxiredoxin activity
AL468_RS04395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL468_RS04400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL468_RS04415	COG1278	Cold shock
AL468_RS04420	COG1741	Belongs to the pirin family
AL468_RS04425	COG4667	esterase of the alpha-beta hydrolase superfamily
AL468_RS04445	COG2194	sulfuric ester hydrolase activity
AL468_RS04450	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL468_RS04460	COG2205	protein histidine kinase activity
AL468_RS04465	COG0745	RESPONSE REGULATOR receiver
AL468_RS04480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL468_RS04500	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL468_RS04510	COG2814	Major facilitator Superfamily
AL468_RS04525	COG1418	mRNA catabolic process
AL468_RS04530	COG0402	S-adenosylhomocysteine deaminase activity
AL468_RS04535	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL468_RS04540	COG2239	Acts as a magnesium transporter
AL468_RS04545	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL468_RS04550	COG1566	PFAM secretion protein HlyD family protein
AL468_RS04575	COG0745	RESPONSE REGULATOR receiver
AL468_RS04580	COG2205	protein histidine kinase activity
AL468_RS04595	COG0531	amino acid
AL468_RS04610	COG0583	DNA-binding transcription factor activity
AL468_RS04635	COG2205	protein histidine kinase activity
AL468_RS04635	COG5002	protein histidine kinase activity
AL468_RS04635	COG0784	Response regulator, receiver
AL468_RS04640	COG0534	Mate efflux family protein
AL468_RS04655	COG3132	Protein of unknown function, DUF480
AL468_RS04660	COG2827	Endonuclease containing a URI domain
AL468_RS04670	COG1879	ABC-type sugar transport system periplasmic component
AL468_RS04675	COG0784	Response regulator, receiver
AL468_RS04675	COG2205	protein histidine kinase activity
AL468_RS04735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL468_RS04740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL468_RS04750	COG1280	lysine exporter protein (LysE YggA)
AL468_RS04760	COG0183	Belongs to the thiolase family
AL468_RS04770	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL468_RS04780	COG3005	denitrification pathway
AL468_RS04790	COG0243	molybdopterin cofactor binding
AL468_RS04800	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL468_RS04805	COG3850	Histidine kinase
AL468_RS04810	COG2197	response regulator
AL468_RS04825	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL468_RS04845	COG0840	transmembrane signaling receptor activity
AL468_RS04855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL468_RS04870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL468_RS04875	COG2814	Major facilitator Superfamily
AL468_RS04880	COG0840	transmembrane signaling receptor activity
AL468_RS04885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL468_RS04890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL468_RS04920	COG2897	thiosulfate sulfurtransferase activity
AL468_RS04940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL468_RS04955	COG1914	H( )-stimulated, divalent metal cation uptake system
AL468_RS04965	COG0038	chloride channel
AL468_RS04980	COG4989	oxidoreductase activity
AL468_RS04995	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL468_RS04995	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL468_RS05005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL468_RS05020	COG1013	pyruvate-flavodoxin oxidoreductase activity
AL468_RS05025	COG0674	pyruvate-flavodoxin oxidoreductase activity
AL468_RS05025	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AL468_RS05035	COG0739	heme binding
AL468_RS05060	COG2204	response regulator
AL468_RS05075	COG3501	Rhs element vgr protein
AL468_RS05100	COG0515	serine threonine protein kinase
AL468_RS05135	COG1522	sequence-specific DNA binding
AL468_RS05210	COG2814	Major facilitator Superfamily
AL468_RS05220	COG0583	DNA-binding transcription factor activity
AL468_RS05225	COG4221	oxidoreductase activity
AL468_RS05230	COG0589	response to stress
AL468_RS05240	COG2111	Na H antiporter
AL468_RS05240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL468_RS05260	COG2212	antiporter activity
AL468_RS05265	COG1320	monovalent cation:proton antiporter activity
AL468_RS05270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL468_RS05355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL468_RS05370	COG3527	Alpha-acetolactate decarboxylase
AL468_RS05380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL468_RS05385	COG0384	phenazine biosynthesis protein PhzF
AL468_RS05395	COG1294	oxidase, subunit
AL468_RS05400	COG1271	oxidase subunit
AL468_RS05405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL468_RS05425	COG3850	Histidine kinase
AL468_RS05425	COG4999	Histidine kinase
AL468_RS05425	COG3437	response regulator, receiver
AL468_RS05425	COG2205	protein histidine kinase activity
AL468_RS05435	COG4770	biotin carboxylase activity
AL468_RS05445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL468_RS05450	COG1960	acyl-CoA dehydrogenase activity
AL468_RS05460	COG0183	Belongs to the thiolase family
AL468_RS05470	COG1960	acyl-CoA dehydrogenase activity
AL468_RS05475	COG1024	Enoyl-CoA hydratase
AL468_RS05490	COG1028	Short-chain dehydrogenase reductase Sdr
AL468_RS05500	COG1309	transcriptional regulator
AL468_RS05505	COG1012	belongs to the aldehyde dehydrogenase family
AL468_RS05520	COG4176	ABC-type proline glycine betaine transport system permease component
AL468_RS05525	COG0517	IMP dehydrogenase activity
AL468_RS05525	COG4175	Glycine betaine
AL468_RS05540	COG0330	HflC and HflK could
AL468_RS05550	COG5001	Diguanylate cyclase
AL468_RS05550	COG3300	MHYT domain
AL468_RS05560	COG0784	Response regulator, receiver
AL468_RS05560	COG2205	protein histidine kinase activity
AL468_RS05570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL468_RS05620	COG5001	Diguanylate cyclase
AL468_RS05625	COG1869	D-ribose catabolic process
AL468_RS05630	COG1129	ABC transporter
AL468_RS05635	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL468_RS05640	COG1879	ABC-type sugar transport system periplasmic component
AL468_RS05645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL468_RS05650	COG1609	Transcriptional regulator
AL468_RS05675	COG4607	ABC-type enterochelin transport system periplasmic component
AL468_RS05680	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL468_RS05685	COG4605	iron ion homeostasis
AL468_RS05690	COG4604	ABC transporter, ATP-binding protein
AL468_RS05695	COG0789	Transcriptional regulator
AL468_RS05700	COG2207	Transcriptional regulator
AL468_RS05705	COG4771	TonB-dependent receptor
AL468_RS05705	COG1629	transport
AL468_RS05735	COG1289	transmembrane transporter activity
AL468_RS05740	COG0210	DNA helicase
AL468_RS05745	COG1803	Methylglyoxal synthase
AL468_RS05750	COG1879	ABC-type sugar transport system periplasmic component
AL468_RS05755	COG2205	protein histidine kinase activity
AL468_RS05755	COG2198	Histidine kinase
AL468_RS05755	COG0784	Response regulator, receiver
AL468_RS05775	COG3119	arylsulfatase activity
AL468_RS05785	COG3119	arylsulfatase activity
AL468_RS05790	COG0641	radical SAM
AL468_RS05795	COG0714	Associated with various cellular activities
AL468_RS05825	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL468_RS05825	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL468_RS05830	COG0583	DNA-binding transcription factor activity
AL468_RS05835	COG1597	lipid kinase activity
AL468_RS05840	COG3111	PFAM Bacterial OB fold (BOF) protein
AL468_RS05865	COG0501	Belongs to the peptidase M48B family
AL468_RS05870	COG1704	LemA family
AL468_RS05875	COG3069	C4-dicarboxylate transmembrane transporter activity
AL468_RS05885	COG0456	acetyltransferase
AL468_RS05885	COG1214	PFAM Peptidase M22, glycoprotease
AL468_RS05905	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AL468_RS05910	COG5001	Diguanylate cyclase
AL468_RS05910	COG3300	MHYT domain
AL468_RS05915	COG3706	GGDEF domain
AL468_RS05925	COG2197	response regulator
AL468_RS05930	COG0784	Response regulator, receiver
AL468_RS05930	COG0835	chemotaxis
AL468_RS05945	COG2962	Rard protein
AL468_RS06010	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AL468_RS06015	COG5642	Protein of unknown function (DUF2384)
AL468_RS06035	COG1902	pentaerythritol trinitrate reductase activity
AL468_RS06040	COG0346	lactoylglutathione lyase activity
AL468_RS06060	COG2239	Acts as a magnesium transporter
AL468_RS06090	COG0242	peptide deformylase activity
AL468_RS06130	COG2176	DNA-directed DNA polymerase activity
AL468_RS06165	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL468_RS06165	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL468_RS06170	COG0509	glycine decarboxylation via glycine cleavage system
AL468_RS06175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL468_RS06185	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL468_RS06195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL468_RS06215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL468_RS06215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL468_RS06215	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL468_RS06220	COG1105	Belongs to the carbohydrate kinase PfkB family
AL468_RS06225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL468_RS06225	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL468_RS06230	COG1609	Transcriptional regulator
AL468_RS06245	COG2199	diguanylate cyclase activity
AL468_RS06245	COG2200	EAL domain
AL468_RS06245	COG2203	Gaf domain
AL468_RS06250	COG0765	amino acid transport
AL468_RS06255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL468_RS06260	COG0765	amino acid transport
AL468_RS06265	COG1126	abc transporter atp-binding protein
AL468_RS06275	COG1979	alcohol dehydrogenase
AL468_RS06280	COG2207	Transcriptional regulator
AL468_RS06295	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL468_RS06300	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AL468_RS06305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL468_RS06320	COG0546	phosphoglycolate phosphatase activity
AL468_RS06345	COG0513	Belongs to the DEAD box helicase family
AL468_RS06350	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL468_RS06365	COG3038	cytochrome b561
AL468_RS06370	COG2353	YceI-like domain
AL468_RS06375	COG2116	formate transmembrane transporter activity
AL468_RS06385	COG0583	DNA-binding transcription factor activity
AL468_RS06395	COG3593	DNA synthesis involved in DNA repair
AL468_RS06400	COG0737	Belongs to the 5'-nucleotidase family
AL468_RS06425	COG2267	carboxylic ester hydrolase activity
AL468_RS06430	COG2067	long-chain fatty acid transport protein
AL468_RS06445	COG2050	protein possibly involved in aromatic compounds catabolism
AL468_RS06455	COG4533	DNA binding
AL468_RS06490	COG5001	Diguanylate cyclase
AL468_RS06490	COG1716	ATPase activity
AL468_RS06495	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL468_RS06505	COG4181	ATPase activity
AL468_RS06510	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL468_RS06520	COG1984	allophanate hydrolase subunit 2
AL468_RS06525	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL468_RS06530	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL468_RS06535	COG3447	MASE1 domain protein
AL468_RS06535	COG5002	protein histidine kinase activity
AL468_RS06535	COG5001	Diguanylate cyclase
AL468_RS06540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL468_RS06555	COG0583	DNA-binding transcription factor activity
AL468_RS06560	COG1042	CoA-binding domain protein
AL468_RS06560	COG0045	succinate-CoA ligase (ADP-forming) activity
AL468_RS06560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL468_RS06570	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL468_RS06580	COG0023	Translation Initiation Factor
AL468_RS06630	COG4128	Pfam Zonular occludens toxin
AL468_RS06660	COG0583	DNA-binding transcription factor activity
AL468_RS06670	COG0589	response to stress
AL468_RS06675	COG3140	Belongs to the UPF0181 family
AL468_RS06700	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL468_RS06705	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL468_RS06730	COG4251	negative regulation of phosphorylation
AL468_RS06730	COG5001	Diguanylate cyclase
AL468_RS06730	COG2203	Gaf domain
AL468_RS06730	COG3706	GGDEF domain
AL468_RS06740	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL468_RS06745	COG4149	molybdate abc transporter
AL468_RS06750	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL468_RS06760	COG3111	PFAM Bacterial OB fold (BOF) protein
AL468_RS06770	COG0189	ligase activity
AL468_RS06770	COG4067	protein conserved in archaea
AL468_RS06780	COG2207	Transcriptional regulator
AL468_RS06785	COG0534	Mate efflux family protein
AL468_RS06790	COG0602	queuosine metabolic process
AL468_RS06795	COG1328	CTP reductase activity
AL468_RS06810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL468_RS06915	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL468_RS06920	COG1794	racemase activity, acting on amino acids and derivatives
AL468_RS06925	COG0384	phenazine biosynthesis protein PhzF
AL468_RS06935	COG0243	molybdopterin cofactor binding
AL468_RS06945	COG0583	DNA-binding transcription factor activity
AL468_RS06950	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL468_RS06960	COG2197	response regulator
AL468_RS06965	COG3851	Histidine kinase
AL468_RS06970	COG2271	Major facilitator Superfamily
AL468_RS06995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL468_RS07000	COG3118	belongs to the thioredoxin family
AL468_RS07040	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL468_RS07060	COG2116	formate transmembrane transporter activity
AL468_RS07070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL468_RS07075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL468_RS07085	COG5001	Diguanylate cyclase
AL468_RS07165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL468_RS07200	COG0277	FAD linked oxidase domain protein
AL468_RS07205	COG0583	DNA-binding transcription factor activity
AL468_RS07220	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AL468_RS07235	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL468_RS07245	COG1288	antiporter activity
AL468_RS07255	COG3040	lipid binding
AL468_RS07265	COG0419	ATPase involved in DNA repair
AL468_RS07270	COG0420	3'-5' exonuclease activity
AL468_RS07285	COG3501	Rhs element vgr protein
AL468_RS07340	COG0631	protein serine/threonine phosphatase activity
AL468_RS07375	COG2815	serine threonine protein kinase
AL468_RS07375	COG0515	serine threonine protein kinase
AL468_RS07425	COG2146	nitrite reductase [NAD(P)H] activity
AL468_RS07425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL468_RS07430	COG1116	anion transmembrane transporter activity
AL468_RS07435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL468_RS07440	COG1116	anion transmembrane transporter activity
AL468_RS07440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL468_RS07465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL468_RS07465	COG1648	precorrin-2 dehydrogenase activity
AL468_RS07470	COG0243	molybdopterin cofactor binding
AL468_RS07480	COG0814	amino acid
AL468_RS07490	COG3706	GGDEF domain
AL468_RS07540	COG2847	Copper chaperone PCu(A)C
AL468_RS07545	COG0443	Heat shock 70 kDa protein
AL468_RS07615	COG4160	amino acid transport
AL468_RS07620	COG4215	(ABC) transporter
AL468_RS07625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL468_RS07630	COG1126	abc transporter atp-binding protein
AL468_RS07660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL468_RS07670	COG1012	belongs to the aldehyde dehydrogenase family
AL468_RS07690	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL468_RS07690	COG1902	pentaerythritol trinitrate reductase activity
AL468_RS07700	COG0109	protoheme IX farnesyltransferase activity
AL468_RS07705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL468_RS07710	COG1845	cytochrome c oxidase, subunit III
AL468_RS07715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL468_RS07720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL468_RS07725	COG1028	Short-chain dehydrogenase reductase Sdr
AL468_RS07735	COG1024	Enoyl-CoA hydratase
AL468_RS07740	COG1024	Enoyl-CoA hydratase
AL468_RS07755	COG0183	Belongs to the thiolase family
AL468_RS07765	COG1960	acyl-CoA dehydrogenase activity
AL468_RS07770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL468_RS07775	COG1024	Enoyl-CoA hydratase
AL468_RS07785	COG5413	integral membrane protein
AL468_RS07795	COG0247	lactate metabolic process
AL468_RS07795	COG0277	FAD linked oxidase domain protein
AL468_RS07850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL468_RS07865	COG0513	Belongs to the DEAD box helicase family
AL468_RS07870	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AL468_RS07900	COG0840	transmembrane signaling receptor activity
AL468_RS07905	COG1119	ATPase activity
AL468_RS07910	COG2200	EAL domain
AL468_RS07930	COG0513	Belongs to the DEAD box helicase family
AL468_RS07935	COG0523	cobalamin synthesis protein
AL468_RS07945	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AL468_RS07955	COG1278	Cold shock
AL468_RS07960	COG0557	exoribonuclease II activity
AL468_RS07965	COG0133	tryptophan synthase activity
AL468_RS07975	COG4628	conserved protein (DUF2132)
AL468_RS07980	COG0513	Belongs to the DEAD box helicase family
AL468_RS07990	COG0730	response to heat
AL468_RS08015	COG1404	Belongs to the peptidase S8 family
AL468_RS08035	COG3530	Putative quorum-sensing-regulated virulence factor
AL468_RS08060	COG3186	Phenylalanine-4-hydroxylase
AL468_RS08065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL468_RS08070	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL468_RS08095	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL468_RS08100	COG1454	alcohol dehydrogenase
AL468_RS08105	COG2133	pyrroloquinoline quinone binding
AL468_RS08115	COG0783	Belongs to the Dps family
AL468_RS08120	COG0840	transmembrane signaling receptor activity
AL468_RS08130	COG0577	efflux transmembrane transporter activity
AL468_RS08130	COG1136	(ABC) transporter
AL468_RS08150	COG2199	diguanylate cyclase activity
AL468_RS08155	COG3036	rescue of stalled ribosome
AL468_RS08160	COG1278	Cold shock
AL468_RS08180	COG2885	chlorophyll binding
AL468_RS08190	COG0545	Peptidyl-prolyl cis-trans isomerase
AL468_RS08195	COG0109	protoheme IX farnesyltransferase activity
AL468_RS08200	COG1612	heme a metabolic process
AL468_RS08225	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AL468_RS08230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL468_RS08235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL468_RS08240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL468_RS08250	COG1280	lysine exporter protein (LysE YggA)
AL468_RS08255	COG2207	Transcriptional regulator
AL468_RS08270	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL468_RS08290	COG0697	spore germination
AL468_RS08310	COG2814	Major facilitator Superfamily
AL468_RS08315	COG0583	DNA-binding transcription factor activity
AL468_RS08320	COG5001	Diguanylate cyclase
AL468_RS08325	COG0739	heme binding
AL468_RS08355	COG0840	transmembrane signaling receptor activity
AL468_RS08365	COG0814	amino acid
AL468_RS08380	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AL468_RS08385	COG1072	(Pantothenic acid kinase))
AL468_RS08395	COG1063	alcohol dehydrogenase
AL468_RS08400	COG2213	PTS system mannitol-specific
AL468_RS08405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL468_RS08425	COG0798	PFAM Bile acid sodium symporter
AL468_RS08435	COG1881	PFAM PEBP family protein
AL468_RS08445	COG2706	6-phosphogluconolactonase activity
AL468_RS08455	COG1131	(ABC) transporter
AL468_RS08460	COG0842	Transport permease protein
AL468_RS08500	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL468_RS08530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL468_RS08540	COG2067	long-chain fatty acid transport protein
AL468_RS08550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL468_RS08560	COG1505	serine-type exopeptidase activity
AL468_RS08565	COG0488	(ABC) transporter
AL468_RS08570	COG0589	response to stress
AL468_RS08575	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL468_RS08595	COG1448	Aminotransferase
AL468_RS08610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL468_RS08620	COG0017	Asparaginyl-tRNA synthetase
AL468_RS08625	COG0840	transmembrane signaling receptor activity
AL468_RS08630	COG0720	synthase
AL468_RS08640	COG2200	EAL domain
AL468_RS08645	COG1760	l-serine dehydratase
AL468_RS08650	COG0814	amino acid
AL468_RS08655	COG0494	nUDIX hydrolase
AL468_RS08665	COG2205	protein histidine kinase activity
AL468_RS08665	COG0784	Response regulator, receiver
AL468_RS08670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL468_RS08690	COG3106	COG3106 Predicted ATPase
AL468_RS08695	COG3768	UPF0283 membrane protein
AL468_RS08705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL468_RS08795	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL468_RS08915	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL468_RS09025	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL468_RS09215	COG1028	Short-chain dehydrogenase reductase Sdr
AL468_RS09260	COG0346	lactoylglutathione lyase activity
AL468_RS09425	COG0455	bacterial-type flagellum organization
AL468_RS09435	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL468_RS09435	COG0456	acetyltransferase
AL468_RS09720	COG0307	riboflavin synthase, alpha
AL468_RS09840	COG2801	Transposase and inactivated derivatives
AL468_RS09895	COG0625	glutathione transferase activity
AL468_RS09965	COG5507	3-demethylubiquinone-9 3-methyltransferase
AL468_RS09975	COG1280	lysine exporter protein (LysE YggA)
AL468_RS10000	COG0583	DNA-binding transcription factor activity
AL468_RS10010	COG1566	PFAM secretion protein HlyD family protein
AL468_RS10025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL468_RS10040	COG3290	protein histidine kinase activity
AL468_RS10045	COG4565	transcriptional regulatory protein
AL468_RS10050	COG4774	siderophore transport
AL468_RS10060	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL468_RS10065	COG0363	glucosamine-6-phosphate deaminase activity
AL468_RS10070	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL468_RS10090	COG3284	Transcriptional regulator
AL468_RS10095	COG1012	belongs to the aldehyde dehydrogenase family
AL468_RS10165	COG4669	(LipO)protein
AL468_RS10185	COG3177	Filamentation induced by cAMP protein fic
AL468_RS10215	COG1028	Short-chain dehydrogenase reductase Sdr
AL468_RS10245	COG4792	protein secretion
AL468_RS10250	COG4791	protein targeting
AL468_RS10255	COG4794	Type iii secretion
AL468_RS10260	COG4790	Type iii secretion
AL468_RS10330	COG0457	Tetratricopeptide repeat
AL468_RS10350	COG2358	TRAP transporter, solute receptor (TAXI family
AL468_RS10355	COG0730	response to heat
AL468_RS10390	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AL468_RS10395	COG0372	Belongs to the citrate synthase family
AL468_RS10405	COG2828	Protein conserved in bacteria
AL468_RS10430	COG0561	phosphatase activity
AL468_RS10435	COG0602	queuosine metabolic process
AL468_RS10440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL468_RS10445	COG3706	GGDEF domain
AL468_RS10495	COG1254	Belongs to the acylphosphatase family
AL468_RS10500	COG2920	part of a sulfur-relay system
AL468_RS10510	COG0670	Belongs to the BI1 family
AL468_RS10515	COG1126	abc transporter atp-binding protein
AL468_RS10520	COG0765	amino acid transport
AL468_RS10525	COG4597	amino acid ABC transporter
AL468_RS10530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL468_RS10545	COG1666	GTP binding
AL468_RS10550	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL468_RS10575	COG3008	intermembrane lipid transfer
AL468_RS10580	COG2995	paraquat-inducible protein a
AL468_RS10585	COG1132	(ABC) transporter
AL468_RS10590	COG1956	GAF domain-containing protein
AL468_RS10595	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AL468_RS10610	COG0308	aminopeptidase N
AL468_RS10620	COG2902	Dehydrogenase
AL468_RS10625	COG0167	dihydroorotate dehydrogenase activity
AL468_RS10635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL468_RS10635	COG0116	Belongs to the methyltransferase superfamily
AL468_RS10660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL468_RS10665	COG1067	ATP-dependent peptidase activity
AL468_RS10670	COG3120	sequence-specific DNA binding
AL468_RS10700	COG2205	protein histidine kinase activity
AL468_RS10700	COG0784	Response regulator, receiver
AL468_RS10715	COG3278	Belongs to the heme-copper respiratory oxidase family
AL468_RS10730	COG2010	Cytochrome c
AL468_RS10740	COG2217	Heavy metal translocating P-type atpase
AL468_RS10755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL468_RS10760	COG0589	response to stress
AL468_RS10785	COG3842	ATPase activity
AL468_RS10795	COG1177	transmembrane transport
AL468_RS10805	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL468_RS10810	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL468_RS10815	COG0004	ammonium transporteR
AL468_RS10845	COG0437	4 iron, 4 sulfur cluster binding
AL468_RS10850	COG3383	formate dehydrogenase (NAD+) activity
AL468_RS10850	COG0243	molybdopterin cofactor binding
AL468_RS10860	COG3381	protein complex oligomerization
AL468_RS10880	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL468_RS10885	COG0488	(ABC) transporter
AL468_RS10895	COG4191	Histidine kinase
AL468_RS10900	COG2204	response regulator
AL468_RS10915	COG3842	ATPase activity
AL468_RS10920	COG0746	molybdenum cofactor guanylyltransferase activity
AL468_RS10935	COG1940	carbohydrate kinase activity
AL468_RS10975	COG0791	NLP P60 protein
AL468_RS10985	COG3706	GGDEF domain
AL468_RS10995	COG3001	Fructosamine kinase
AL468_RS11005	COG0307	riboflavin synthase, alpha
AL468_RS11010	COG0534	Mate efflux family protein
AL468_RS11020	COG1793	dna ligase
AL468_RS11050	COG2204	response regulator
AL468_RS11055	COG0297	glycogen (starch) synthase activity
AL468_RS11060	COG0438	transferase activity, transferring glycosyl groups
AL468_RS11090	COG0438	transferase activity, transferring glycosyl groups
AL468_RS11095	COG1215	transferase activity, transferring glycosyl groups
AL468_RS11100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL468_RS11110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL468_RS11125	COG1643	Atp-dependent helicase
AL468_RS11130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL468_RS11175	COG0443	Heat shock 70 kDa protein
AL468_RS11180	COG0443	Heat shock 70 kDa protein
AL468_RS11200	COG4968	Prepilin-type N-terminal cleavage methylation domain
AL468_RS11205	COG1132	(ABC) transporter
AL468_RS11210	COG1132	(ABC) transporter
AL468_RS11220	COG4774	siderophore transport
AL468_RS11230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL468_RS11235	COG1120	ATPase activity
AL468_RS11250	COG0814	amino acid
AL468_RS11260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL468_RS11270	COG0861	Integral membrane protein TerC family
AL468_RS11280	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL468_RS11285	COG1328	CTP reductase activity
AL468_RS11300	COG5001	Diguanylate cyclase
AL468_RS11300	COG3300	MHYT domain
AL468_RS11310	COG4191	Histidine kinase
AL468_RS11315	COG0471	metal ion transport
AL468_RS11340	COG4702	Belongs to the UPF0303 family
AL468_RS11345	COG0673	inositol 2-dehydrogenase activity
AL468_RS11350	COG1349	DNA-binding transcription factor activity
AL468_RS11365	COG0641	radical SAM
AL468_RS11380	COG3119	arylsulfatase activity
AL468_RS11385	COG0527	aspartate kinase activity
AL468_RS11390	COG0662	Cupin 2, conserved barrel domain protein
AL468_RS11395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL468_RS11400	COG0456	acetyltransferase
AL468_RS11405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL468_RS11425	COG4176	ABC-type proline glycine betaine transport system permease component
AL468_RS11430	COG2113	Glycine betaine
AL468_RS11450	COG1028	Short-chain dehydrogenase reductase Sdr
AL468_RS11460	COG0745	RESPONSE REGULATOR receiver
AL468_RS11465	COG0642	Histidine kinase
AL468_RS11470	COG1368	sulfuric ester hydrolase activity
AL468_RS11495	COG1115	amino acid carrier protein
AL468_RS11505	COG1280	lysine exporter protein (LysE YggA)
AL468_RS11510	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AL468_RS11515	COG1560	Kdo2-lipid A biosynthetic process
AL468_RS11520	COG0531	amino acid
AL468_RS11535	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AL468_RS11540	COG3063	Type IV pilus biogenesis stability protein PilW
AL468_RS11570	COG0110	maltose O-acetyltransferase activity
AL468_RS11585	COG2315	Protein conserved in bacteria
AL468_RS11590	COG1846	Transcriptional regulator
AL468_RS11600	COG2200	EAL domain
AL468_RS11600	COG2771	luxR family
AL468_RS11635	COG0625	glutathione transferase activity
AL468_RS11645	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL468_RS11655	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL468_RS11665	COG0601	transmembrane transport
AL468_RS11670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL468_RS11690	COG3291	Pkd domain containing protein
AL468_RS11700	COG1177	transmembrane transport
AL468_RS11705	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL468_RS11710	COG3842	ATPase activity
AL468_RS11715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL468_RS11720	COG2423	ornithine cyclodeaminase activity
AL468_RS11735	COG3938	Belongs to the proline racemase family
AL468_RS11765	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AL468_RS11770	COG1451	nucleotide metabolic process
AL468_RS11780	COG0583	DNA-binding transcription factor activity
AL468_RS11800	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AL468_RS11805	COG4139	cobalamin transport
AL468_RS11810	COG2988	succinylglutamate desuccinylase activity
AL468_RS11830	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AL468_RS11835	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AL468_RS11840	COG0702	epimerase
AL468_RS11850	COG2925	Exonuclease
AL468_RS11855	COG1380	Effector of murein hydrolase LrgA
AL468_RS11860	COG1346	cytolysis
AL468_RS11865	COG0295	cytidine deaminase activity
AL468_RS11870	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL468_RS11875	COG0500	methyltransferase
AL468_RS11885	COG0776	regulation of translation
AL468_RS11895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL468_RS11895	COG0072	phenylalanine-tRNA ligase activity
AL468_RS11900	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL468_RS11930	COG0393	Putative heavy-metal-binding
AL468_RS11940	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL468_RS11950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL468_RS11965	COG2188	Transcriptional regulator
AL468_RS11970	COG1228	amidohydrolase
AL468_RS11975	COG0010	Belongs to the arginase family
AL468_RS11980	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL468_RS11985	COG2986	histidine ammonia-lyase
AL468_RS12000	COG0247	lactate metabolic process
AL468_RS12000	COG0277	FAD linked oxidase domain protein
AL468_RS12035	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL468_RS12050	COG1643	Atp-dependent helicase
AL468_RS12055	COG0281	malic enzyme
AL468_RS12060	COG2949	membrane
AL468_RS12065	COG0471	metal ion transport
AL468_RS12090	COG0492	ferredoxin-NADP+ reductase activity
AL468_RS12095	COG4988	ABC transporter
AL468_RS12100	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL468_RS12110	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL468_RS12120	COG4191	Histidine kinase
AL468_RS12120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL468_RS12135	COG3070	regulator of competence-specific genes
AL468_RS12150	COG2431	L-lysine efflux transmembrane transporter activity
AL468_RS12160	COG0076	glutamate decarboxylase activity
AL468_RS12165	COG1737	Transcriptional regulator
AL468_RS12180	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL468_RS12185	COG2985	domain, Protein
AL468_RS12185	COG3273	potassium ion transport
AL468_RS12190	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL468_RS12195	COG1960	acyl-CoA dehydrogenase activity
AL468_RS12210	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL468_RS12230	COG0534	Mate efflux family protein
AL468_RS12235	COG0702	epimerase
AL468_RS12240	COG3005	denitrification pathway
AL468_RS12270	COG2814	Major facilitator Superfamily
AL468_RS12280	COG1187	pseudouridine synthase activity
AL468_RS12285	COG1061	Type III restriction enzyme res subunit
AL468_RS12295	COG0745	RESPONSE REGULATOR receiver
AL468_RS12300	COG2205	protein histidine kinase activity
AL468_RS12310	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL468_RS12330	COG3313	Fe-S protein
AL468_RS12340	COG4134	Bacterial extracellular solute-binding protein
AL468_RS12345	COG4135	transport system, permease component
AL468_RS12350	COG4136	ATPase activity
AL468_RS12355	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL468_RS12370	COG3604	Transcriptional regulator
AL468_RS12375	COG1151	hydroxylamine reductase activity
AL468_RS12380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL468_RS12390	COG0564	pseudouridine synthase activity
AL468_RS12395	COG0733	neurotransmitter:sodium symporter activity
AL468_RS12405	COG0626	cystathionine gamma-synthase activity
AL468_RS12410	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AL468_RS12415	COG5380	lipid catabolic process
AL468_RS12420	COG2818	Glycosylase
AL468_RS12440	COG1983	PspC domain protein
AL468_RS12450	COG1842	Phage shock protein A
AL468_RS12455	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL468_RS12470	COG4171	peptide transport system, permease
AL468_RS12480	COG4172	Belongs to the ABC transporter superfamily
AL468_RS12490	COG1227	inorganic diphosphatase activity
AL468_RS12505	COG0243	molybdopterin cofactor binding
AL468_RS12510	COG3005	denitrification pathway
AL468_RS12515	COG4459	periplasmic nitrate reductase
AL468_RS12520	COG0390	transport system, permease component
AL468_RS12530	COG2116	formate transmembrane transporter activity
AL468_RS12555	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL468_RS12560	COG1435	thymidine kinase activity
AL468_RS12565	COG0215	cysteine-tRNA ligase activity
AL468_RS12570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL468_RS12575	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL468_RS12580	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AL468_RS12585	COG3012	SEC-C Motif Domain Protein
AL468_RS12590	COG0140	phosphoribosyl-ATP diphosphatase activity
AL468_RS12590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL468_RS12600	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL468_RS12605	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL468_RS12610	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL468_RS12610	COG0131	Imidazoleglycerol-phosphate dehydratase
AL468_RS12615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL468_RS12620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL468_RS12625	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL468_RS12635	COG1757	Na H antiporter
AL468_RS12645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL468_RS12655	COG0482	sulfurtransferase activity
AL468_RS12660	COG2915	High frequency lysogenization protein hflD homolog
AL468_RS12665	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL468_RS12675	COG2268	Band 7 protein
AL468_RS12685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL468_RS12700	COG0300	oxidoreductase activity
AL468_RS12720	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL468_RS12760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL468_RS12765	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AL468_RS12770	COG1674	ftsk spoiiie
AL468_RS12780	COG0686	Belongs to the AlaDH PNT family
AL468_RS12790	COG0583	DNA-binding transcription factor activity
AL468_RS12805	COG0840	transmembrane signaling receptor activity
AL468_RS12815	COG3568	Endonuclease Exonuclease Phosphatase
AL468_RS12840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL468_RS12845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL468_RS12850	COG0840	transmembrane signaling receptor activity
AL468_RS12865	COG0784	Response regulator, receiver
AL468_RS12865	COG5002	protein histidine kinase activity
AL468_RS12875	COG0754	glutathionylspermidine amidase activity
AL468_RS12885	COG3766	membrane
AL468_RS12895	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL468_RS12900	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AL468_RS12905	COG2885	chlorophyll binding
AL468_RS12910	COG0823	Involved in the tonB-independent uptake of proteins
AL468_RS12925	COG0811	peptide transport
AL468_RS12930	COG0824	Thioesterase
AL468_RS12940	COG4890	Cyd operon protein YbgT
AL468_RS12945	COG1294	oxidase, subunit
AL468_RS12950	COG1271	oxidase subunit
AL468_RS12955	COG2255	four-way junction helicase activity
AL468_RS12960	COG0632	four-way junction helicase activity
AL468_RS12965	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AL468_RS12970	COG0217	transcriptional regulatory protein
AL468_RS12980	COG1801	Protein of unknown function DUF72
AL468_RS12990	COG0500	methyltransferase
AL468_RS13000	COG0189	ligase activity
AL468_RS13000	COG4067	protein conserved in archaea
AL468_RS13020	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AL468_RS13025	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AL468_RS13030	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AL468_RS13035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL468_RS13040	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL468_RS13045	COG0745	RESPONSE REGULATOR receiver
AL468_RS13050	COG3381	protein complex oligomerization
AL468_RS13055	COG1609	Transcriptional regulator
AL468_RS13060	COG3070	regulator of competence-specific genes
AL468_RS13080	COG0297	glycogen (starch) synthase activity
AL468_RS13085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL468_RS13090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL468_RS13110	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AL468_RS13115	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AL468_RS13120	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL468_RS13125	COG0542	response to heat
AL468_RS13130	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL468_RS13135	COG1278	Cold shock
AL468_RS13145	COG1187	pseudouridine synthase activity
AL468_RS13150	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL468_RS13155	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL468_RS13160	COG1199	ATP-dependent helicase activity
AL468_RS13165	COG0730	response to heat
AL468_RS13170	COG3923	Primosomal replication protein n
AL468_RS13180	COG0708	Exodeoxyribonuclease III
AL468_RS13225	COG1882	Formate acetyltransferase
AL468_RS13235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL468_RS13245	COG3013	Belongs to the UPF0304 family
AL468_RS13255	COG2766	serine protein kinase
AL468_RS13260	COG2718	Belongs to the UPF0229 family
AL468_RS13265	COG2719	SpoVR family
AL468_RS13280	COG1663	tetraacyldisaccharide 4'-kinase activity
AL468_RS13285	COG1132	(ABC) transporter
AL468_RS13290	COG2333	competence protein COMEC
AL468_RS13290	COG0658	competence protein
AL468_RS13300	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL468_RS13305	COG1136	(ABC) transporter
AL468_RS13310	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL468_RS13320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL468_RS13335	COG1252	NADH dehydrogenase
AL468_RS13340	COG3150	esterase
AL468_RS13365	COG0537	adenosine 5'-monophosphoramidase activity
AL468_RS13390	COG0516	GMP reductase activity
AL468_RS13390	COG0517	IMP dehydrogenase activity
AL468_RS13395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL468_RS13420	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AL468_RS13425	COG1946	Acyl-CoA thioesterase
AL468_RS13435	COG1522	sequence-specific DNA binding
AL468_RS13460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL468_RS13465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL468_RS13510	COG0477	Major facilitator Superfamily
AL468_RS13515	COG2855	membrane
AL468_RS13535	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL468_RS13540	COG0596	Alpha beta hydrolase
AL468_RS13545	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AL468_RS13550	COG1169	isochorismate synthase
AL468_RS13555	COG0436	Aminotransferase
AL468_RS13560	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AL468_RS13565	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AL468_RS13580	COG1555	photosystem II stabilization
AL468_RS13585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL468_RS13590	COG0776	regulation of translation
AL468_RS13595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL468_RS13600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL468_RS13610	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL468_RS13635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL468_RS13640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL468_RS13645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL468_RS13650	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AL468_RS13665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL468_RS13670	COG0569	domain protein
AL468_RS13675	COG0513	Belongs to the DEAD box helicase family
AL468_RS13680	COG1253	flavin adenine dinucleotide binding
AL468_RS13715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL468_RS13720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL468_RS13730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL468_RS13735	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL468_RS13740	COG1216	Glycosyl transferase, family 2
AL468_RS13745	COG2986	histidine ammonia-lyase
AL468_RS13770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL468_RS13780	COG1028	Short-chain dehydrogenase reductase Sdr
AL468_RS13850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL468_RS13855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL468_RS13865	COG2951	lytic endotransglycosylase activity
AL468_RS13870	COG3100	YcgL domain-containing protein
AL468_RS13875	COG0850	regulation of cytokinetic process
AL468_RS13880	COG2894	cell division
AL468_RS13885	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL468_RS13890	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AL468_RS13895	COG0318	PFAM AMP-dependent synthetase and ligase
AL468_RS13900	COG2267	carboxylic ester hydrolase activity
AL468_RS13905	COG3065	identical protein binding
AL468_RS13915	COG1214	PFAM Peptidase M22, glycoprotease
AL468_RS13920	COG1199	ATP-dependent helicase activity
AL468_RS13925	COG0788	formyltetrahydrofolate deformylase activity
AL468_RS13940	COG3102	Protein conserved in bacteria
AL468_RS13950	COG0018	arginyl-trna synthetase
AL468_RS13970	COG1918	ferrous iron import across plasma membrane
AL468_RS13975	COG4977	sequence-specific DNA binding
AL468_RS13980	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AL468_RS13985	COG1121	(ABC) transporter
AL468_RS13990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL468_RS14005	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL468_RS14010	COG0567	Dehydrogenase, E1 component
AL468_RS14015	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL468_RS14020	COG1053	succinate dehydrogenase
AL468_RS14025	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL468_RS14040	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL468_RS14050	COG0033	Phosphoglucomutase
AL468_RS14055	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AL468_RS14060	COG0596	Alpha beta hydrolase
AL468_RS14070	COG0716	FMN binding
AL468_RS14080	COG0735	belongs to the Fur family
AL468_RS14085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL468_RS14090	COG1263	PTS System
AL468_RS14090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL468_RS14090	COG2190	(PTS) system
AL468_RS14100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL468_RS14105	COG1940	carbohydrate kinase activity
AL468_RS14105	COG1846	Transcriptional regulator
AL468_RS14110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL468_RS14110	COG4651	solute:proton antiporter activity
AL468_RS14115	COG0367	asparagine synthase
AL468_RS14120	COG0250	Participates in transcription elongation, termination and antitermination
AL468_RS14125	COG3104	oligopeptide transport
AL468_RS14130	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL468_RS14140	COG0326	Molecular chaperone. Has ATPase activity
AL468_RS14145	COG3710	Transcriptional regulator
AL468_RS14165	COG0622	Phosphoesterase
AL468_RS14195	COG1090	epimerase
AL468_RS14200	COG0300	oxidoreductase activity
AL468_RS14210	COG3118	belongs to the thioredoxin family
AL468_RS14215	COG0330	HflC and HflK could
AL468_RS14240	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL468_RS14245	COG3115	cell septum assembly
AL468_RS14250	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AL468_RS14255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL468_RS14265	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL468_RS14270	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL468_RS14275	COG2190	(PTS) system
AL468_RS14280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL468_RS14285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL468_RS14295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL468_RS14300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL468_RS14310	COG3951	Flagellar rod assembly protein muramidase FlgJ
AL468_RS14310	COG1705	Flagellar rod assembly protein muramidase FlgJ
AL468_RS14315	COG1706	bacterial-type flagellum-dependent cell motility
AL468_RS14320	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL468_RS14330	COG4787	bacterial-type flagellum-dependent cell motility
AL468_RS14335	COG1749	Flagellar hook protein flgE
AL468_RS14345	COG1558	bacterial-type flagellum-dependent cell motility
AL468_RS14350	COG1815	bacterial-type flagellum-dependent cell motility
AL468_RS14355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL468_RS14360	COG0784	Response regulator, receiver
AL468_RS14360	COG0835	chemotaxis
AL468_RS14415	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL468_RS14435	COG2217	Heavy metal translocating P-type atpase
AL468_RS14435	COG2608	mercury ion transmembrane transporter activity
AL468_RS14475	COG2840	Smr protein MutS2
AL468_RS14480	COG1187	pseudouridine synthase activity
AL468_RS14490	COG0737	Belongs to the 5'-nucleotidase family
AL468_RS14495	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL468_RS14500	COG2912	Transglutaminase-like superfamily
AL468_RS14505	COG3094	Invasion gene expression up-regulator, SirB
AL468_RS14510	COG2890	protein-(glutamine-N5) methyltransferase activity
AL468_RS14515	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL468_RS14520	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL468_RS14525	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AL468_RS14530	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL468_RS14535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL468_RS14540	COG0193	aminoacyl-tRNA hydrolase activity
AL468_RS14545	COG0012	GTP binding
AL468_RS14655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL468_RS14665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL468_RS14670	COG1702	phosphate starvation-inducible protein PhoH
AL468_RS14675	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL468_RS14680	COG4535	Mg2 and Co2 transporter CorC
AL468_RS14685	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL468_RS14690	COG2888	peptidyl-tyrosine sulfation
AL468_RS14695	COG0495	leucyl-tRNA aminoacylation
AL468_RS14700	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AL468_RS14705	COG1466	dna polymerase III delta subunit
AL468_RS14710	COG0799	negative regulation of ribosome biogenesis
AL468_RS14715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL468_RS14720	COG0768	penicillin binding
AL468_RS14725	COG0772	Belongs to the SEDS family
AL468_RS14730	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL468_RS14735	COG1686	Belongs to the peptidase S11 family
AL468_RS14745	COG0321	lipoyl(octanoyl) transferase activity
AL468_RS14750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL468_RS14755	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL468_RS14760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AL468_RS14775	COG0366	Alpha amylase catalytic
AL468_RS14780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL468_RS14780	COG1263	PTS System
AL468_RS14790	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL468_RS14795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL468_RS14800	COG2011	ABC-type metal ion transport system permease component
AL468_RS14805	COG1464	Belongs to the NlpA lipoprotein family
AL468_RS14810	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
AL468_RS14820	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL468_RS14820	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL468_RS14835	COG1611	Belongs to the LOG family
AL468_RS14840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL468_RS14850	COG2363	Small membrane protein
AL468_RS14860	COG0583	DNA-binding transcription factor activity
AL468_RS14865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL468_RS14865	COG0301	tRNA thio-modification
AL468_RS14875	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AL468_RS14880	COG1722	exodeoxyribonuclease VII activity
AL468_RS14885	COG0142	geranyltranstransferase activity
AL468_RS14890	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL468_RS14895	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL468_RS14900	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AL468_RS14910	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AL468_RS14925	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL468_RS14925	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL468_RS14930	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL468_RS14935	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL468_RS14940	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL468_RS14955	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AL468_RS14965	COG2252	PERMEase
AL468_RS14970	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL468_RS14985	COG1629	transport
AL468_RS15000	COG0047	phosphoribosylformylglycinamidine synthase activity
AL468_RS15000	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL468_RS15005	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL468_RS15020	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL468_RS15045	COG4969	Belongs to the N-Me-Phe pilin family
AL468_RS15055	COG0484	heat shock protein binding
AL468_RS15065	COG1301	dicarboxylic acid transport
AL468_RS15070	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL468_RS15075	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL468_RS15085	COG0497	DNA recombination
AL468_RS15090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL468_RS15095	COG2914	Belongs to the UPF0125 (RnfH) family
AL468_RS15100	COG2867	negative regulation of translational initiation
AL468_RS15105	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL468_RS15120	COG0583	DNA-binding transcription factor activity
AL468_RS15125	COG3153	acetyltransferase
AL468_RS15125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL468_RS15145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL468_RS15150	COG2873	o-acetylhomoserine
AL468_RS15175	COG1115	amino acid carrier protein
AL468_RS15180	COG1584	GPR1 FUN34 yaaH family protein
AL468_RS15190	COG1757	Na H antiporter
AL468_RS15270	COG0582	viral genome integration into host DNA
AL468_RS15275	COG0519	Catalyzes the synthesis of GMP from XMP
AL468_RS15275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL468_RS15280	COG0516	GMP reductase activity
AL468_RS15280	COG0517	IMP dehydrogenase activity
AL468_RS15300	COG1160	GTP binding
AL468_RS15305	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL468_RS15310	COG2976	Protein conserved in bacteria
AL468_RS15315	COG0124	histidyl-tRNA synthetase
AL468_RS15320	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL468_RS15340	COG0105	UTP biosynthetic process
AL468_RS15350	COG2975	iron-sulfur cluster assembly
AL468_RS15355	COG0633	Ferredoxin
AL468_RS15360	COG0443	Heat shock 70 kDa protein
AL468_RS15375	COG0822	iron-sulfur transferase activity
AL468_RS15380	COG1104	cysteine desulfurase activity
AL468_RS15390	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AL468_RS15395	COG0483	inositol monophosphate 1-phosphatase activity
AL468_RS15400	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL468_RS15405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL468_RS15410	COG1862	Preprotein translocase
AL468_RS15420	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL468_RS15435	COG0517	IMP dehydrogenase activity
AL468_RS15445	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL468_RS15450	COG0583	DNA-binding transcription factor activity
AL468_RS15455	COG0450	alkyl hydroperoxide reductase
AL468_RS15460	COG3142	Participates in the control of copper homeostasis
AL468_RS15470	COG0704	Plays a role in the regulation of phosphate uptake
AL468_RS15475	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL468_RS15480	COG0581	inorganic phosphate transmembrane transporter activity
AL468_RS15485	COG0573	inorganic phosphate transmembrane transporter activity
AL468_RS15490	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AL468_RS15495	COG0248	Ppx GppA phosphatase
AL468_RS15505	COG5002	protein histidine kinase activity
AL468_RS15510	COG0745	RESPONSE REGULATOR receiver
AL468_RS15520	COG2974	May be involved in recombination
AL468_RS15530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL468_RS15590	COG0542	response to heat
AL468_RS15600	COG0564	pseudouridine synthase activity
AL468_RS15605	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL468_RS15610	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL468_RS15615	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL468_RS15620	COG1605	Chorismate mutase
AL468_RS15620	COG0077	Prephenate dehydratase
AL468_RS15625	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AL468_RS15630	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AL468_RS15640	COG0488	(ABC) transporter
AL468_RS15650	COG0741	lytic transglycosylase activity
AL468_RS15650	COG1196	nuclear chromosome segregation
AL468_RS15650	COG0739	heme binding
AL468_RS15655	COG0287	Prephenate dehydrogenase
AL468_RS15655	COG1605	Chorismate mutase
AL468_RS15660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL468_RS15665	COG1472	Belongs to the glycosyl hydrolase 3 family
AL468_RS15670	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL468_RS15690	COG1966	Carbon starvation protein
AL468_RS15695	COG3275	phosphorelay sensor kinase activity
AL468_RS15700	COG3279	Response regulator of the LytR AlgR family
AL468_RS15710	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL468_RS15715	COG1047	Peptidyl-prolyl cis-trans
AL468_RS15720	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL468_RS15730	COG0196	riboflavin kinase activity
AL468_RS15735	COG0728	peptidoglycan biosynthetic process
AL468_RS15740	COG0268	Binds directly to 16S ribosomal RNA
AL468_RS15745	COG0640	Transcriptional regulator
AL468_RS15750	COG0583	DNA-binding transcription factor activity
AL468_RS15755	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL468_RS15765	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AL468_RS15775	COG0730	response to heat
AL468_RS15800	COG0667	Aldo Keto reductase
AL468_RS15810	COG2204	response regulator
AL468_RS15815	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AL468_RS15825	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL468_RS15830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL468_RS15835	COG4974	Belongs to the 'phage' integrase family
AL468_RS15840	COG0716	FMN binding
AL468_RS15850	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AL468_RS15855	COG0513	Belongs to the DEAD box helicase family
AL468_RS15860	COG3022	response to hydroperoxide
AL468_RS15865	COG1115	amino acid carrier protein
AL468_RS15880	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL468_RS15890	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AL468_RS15895	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
AL468_RS15905	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL468_RS15910	COG0083	homoserine kinase activity
AL468_RS15930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL468_RS15945	COG0745	RESPONSE REGULATOR receiver
AL468_RS15955	COG0784	Response regulator, receiver
AL468_RS15955	COG5002	protein histidine kinase activity
AL468_RS15955	COG2198	Histidine kinase
AL468_RS15960	COG3706	GGDEF domain
AL468_RS15960	COG2203	Gaf domain
AL468_RS15960	COG4251	negative regulation of phosphorylation
AL468_RS15960	COG5001	Diguanylate cyclase
AL468_RS15965	COG1242	4 iron, 4 sulfur cluster binding
AL468_RS15970	COG0070	glutamate synthase
AL468_RS15970	COG0067	glutamate synthase
AL468_RS15970	COG0069	glutamate synthase activity
AL468_RS15985	COG0493	'glutamate synthase
AL468_RS15995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL468_RS16010	COG2860	membrane
AL468_RS16015	COG0583	DNA-binding transcription factor activity
AL468_RS16030	COG0730	response to heat
AL468_RS16050	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL468_RS16055	COG0505	Belongs to the CarA family
AL468_RS16065	COG0494	nUDIX hydrolase
AL468_RS16070	COG0653	protein targeting
AL468_RS16080	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AL468_RS16085	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL468_RS16090	COG0849	cell division
AL468_RS16095	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL468_RS16100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL468_RS16110	COG0772	Belongs to the SEDS family
AL468_RS16115	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL468_RS16120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL468_RS16125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL468_RS16130	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL468_RS16135	COG0768	penicillin binding
AL468_RS16140	COG3116	cell division
AL468_RS16155	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL468_RS16170	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL468_RS16175	COG2823	Periplasmic or secreted lipoprotein
AL468_RS16180	COG2969	positive regulation of protein catabolic process
AL468_RS16185	COG0625	glutathione transferase activity
AL468_RS16190	COG2857	Cytochrome c1
AL468_RS16195	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL468_RS16200	COG0723	plastoquinol--plastocyanin reductase activity
AL468_RS16205	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL468_RS16210	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL468_RS16220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL468_RS16230	COG3105	Protein conserved in bacteria
AL468_RS16240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL468_RS16255	COG3150	esterase
AL468_RS16265	COG3151	Protein conserved in bacteria
AL468_RS16270	COG0494	nUDIX hydrolase
AL468_RS16275	COG1538	Outer membrane efflux protein
AL468_RS16280	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL468_RS16280	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL468_RS16285	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL468_RS16300	COG3025	triphosphatase activity
AL468_RS16305	COG1392	Phosphate transport regulator
AL468_RS16310	COG0306	phosphate transporter
AL468_RS16315	COG4991	sh3 domain protein
AL468_RS16320	COG0405	Gamma-glutamyltransferase
AL468_RS16330	COG3409	Peptidoglycan-binding domain 1 protein
AL468_RS16330	COG3267	Type II secretory pathway component ExeA
AL468_RS16340	COG1968	undecaprenyl-diphosphatase activity
AL468_RS16345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL468_RS16350	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL468_RS16355	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AL468_RS16360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL468_RS16365	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL468_RS16370	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL468_RS16375	COG1610	YqeY-like protein
AL468_RS16380	COG0358	DNA primase activity
AL468_RS16395	COG1464	Belongs to the NlpA lipoprotein family
AL468_RS16430	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL468_RS16430	COG2213	PTS system mannitol-specific
AL468_RS16440	COG3722	fumarate hydratase activity
AL468_RS16455	COG1461	Dihydroxyacetone kinase
AL468_RS16460	COG2376	Dihydroxyacetone kinase
AL468_RS16470	COG5002	protein histidine kinase activity
AL468_RS16485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL468_RS16490	COG1349	DNA-binding transcription factor activity
AL468_RS16500	COG0469	pyruvate kinase activity
AL468_RS16510	COG3706	GGDEF domain
AL468_RS16520	COG0028	Belongs to the TPP enzyme family
AL468_RS16525	COG1022	Amp-dependent synthetase and ligase
AL468_RS16530	COG0583	DNA-binding transcription factor activity
AL468_RS16555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL468_RS16560	COG0473	3-isopropylmalate dehydrogenase activity
AL468_RS16580	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL468_RS16585	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL468_RS16590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL468_RS16595	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL468_RS16600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL468_RS16605	COG2967	ApaG domain
AL468_RS16610	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL468_RS16625	COG2966	Psort location CytoplasmicMembrane, score
AL468_RS16630	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL468_RS16640	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL468_RS16645	COG0142	geranyltranstransferase activity
AL468_RS16670	COG2358	TRAP transporter, solute receptor (TAXI family
AL468_RS16690	COG1902	pentaerythritol trinitrate reductase activity
AL468_RS16695	COG0583	DNA-binding transcription factor activity
AL468_RS16700	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AL468_RS16705	COG1178	ABC-type Fe3 transport system permease component
AL468_RS16710	COG4143	(ABC) transporter
AL468_RS16715	COG0163	prenyltransferase activity
AL468_RS16720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL468_RS16730	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL468_RS16735	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL468_RS16745	COG2105	PFAM AIG2 family protein
AL468_RS16750	COG2911	Protein conserved in bacteria
AL468_RS16755	COG0729	surface antigen
AL468_RS16760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL468_RS16770	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL468_RS16785	COG4181	ATPase activity
AL468_RS16805	COG0529	Catalyzes the synthesis of activated sulfate
AL468_RS16810	COG0471	metal ion transport
AL468_RS16810	COG3273	potassium ion transport
AL468_RS16815	COG2895	sulfate adenylyltransferase (ATP) activity
AL468_RS16820	COG0175	sulfate reduction
AL468_RS16825	COG1648	precorrin-2 dehydrogenase activity
AL468_RS16825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL468_RS16840	COG0513	Belongs to the DEAD box helicase family
AL468_RS16845	COG2153	protein acetylation
AL468_RS16855	COG0545	Peptidyl-prolyl cis-trans isomerase
AL468_RS16865	COG0203	ribosomal protein L17
AL468_RS16870	COG0202	RNA polymerase activity
AL468_RS16880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL468_RS16885	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL468_RS16890	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL468_RS16895	COG0201	protein transport
AL468_RS16905	COG1841	ribosomal large subunit assembly
AL468_RS16920	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL468_RS16925	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL468_RS16930	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL468_RS16935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL468_RS16940	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL468_RS16950	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL468_RS16955	COG0255	Belongs to the universal ribosomal protein uL29 family
AL468_RS16965	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL468_RS16970	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL468_RS16975	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL468_RS16980	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL468_RS16990	COG0088	Forms part of the polypeptide exit tunnel
AL468_RS16995	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL468_RS17005	COG0254	rRNA binding
AL468_RS17015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL468_RS17020	COG1609	Transcriptional regulator
AL468_RS17030	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL468_RS17035	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL468_RS17040	COG1575	Belongs to the MenA family. Type 1 subfamily
AL468_RS17045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL468_RS17060	COG1494	fructose-1,6-bisphosphatase
AL468_RS17090	COG0149	triose-phosphate isomerase activity
AL468_RS17130	COG0463	Glycosyl transferase, family 2
AL468_RS17150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL468_RS17160	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL468_RS17165	COG1215	transferase activity, transferring glycosyl groups
AL468_RS17170	COG1442	glycosyl transferase family 8
AL468_RS17170	COG1216	Glycosyl transferase, family 2
AL468_RS17225	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL468_RS17235	COG1560	Kdo2-lipid A biosynthetic process
AL468_RS17245	COG0859	PFAM glycosyl transferase family 9
AL468_RS17250	COG1519	Transferase
AL468_RS17255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL468_RS17295	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AL468_RS17305	COG3642	lipopolysaccharide core region biosynthetic process
AL468_RS17310	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL468_RS17315	COG0859	PFAM glycosyl transferase family 9
AL468_RS17320	COG0463	Glycosyl transferase, family 2
AL468_RS17335	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL468_RS17360	COG2003	Belongs to the UPF0758 family
AL468_RS17375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL468_RS17380	COG1309	transcriptional regulator
AL468_RS17385	COG1560	Kdo2-lipid A biosynthetic process
AL468_RS17395	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL468_RS17405	COG1561	YicC-like family, N-terminal region
AL468_RS17440	COG4608	Belongs to the ABC transporter superfamily
AL468_RS17445	COG0444	Belongs to the ABC transporter superfamily
AL468_RS17450	COG0747	negative chemotaxis
AL468_RS17455	COG4239	(ABC) transporter, permease
AL468_RS17460	COG4174	ABC transporter (Permease)
AL468_RS17485	COG0811	peptide transport
AL468_RS17490	COG0848	biopolymer transport protein
AL468_RS17505	COG0194	GDP metabolic process
AL468_RS17510	COG1758	RNA polymerase activity
AL468_RS17515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL468_RS17520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL468_RS17525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL468_RS17530	COG2233	PERMEase
AL468_RS17535	COG2205	protein histidine kinase activity
AL468_RS17540	COG0745	RESPONSE REGULATOR receiver
AL468_RS17550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL468_RS17560	COG2183	response to ionizing radiation
AL468_RS17570	COG0596	Alpha beta hydrolase
AL468_RS17575	COG1040	competence protein
AL468_RS17580	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AL468_RS17580	COG0316	Belongs to the HesB IscA family
AL468_RS17585	COG0494	nUDIX hydrolase
AL468_RS17590	COG1218	3'(2'),5'-bisphosphate nucleotidase
AL468_RS17600	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AL468_RS17605	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AL468_RS17610	COG3156	type II secretion system protein K
AL468_RS17615	COG4795	General secretion pathway protein
AL468_RS17620	COG2165	general secretion pathway protein
AL468_RS17625	COG2165	general secretion pathway protein
AL468_RS17630	COG2165	general secretion pathway protein
AL468_RS17635	COG1459	type II secretion system
AL468_RS17640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL468_RS17650	COG3031	protein transport across the cell outer membrane
AL468_RS17655	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL468_RS17660	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL468_RS17665	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AL468_RS17675	COG0456	acetyltransferase
AL468_RS17680	COG1490	D-aminoacyl-tRNA deacylase activity
AL468_RS17685	COG1295	ribonuclease BN
AL468_RS17710	COG0174	glutamine synthetase
AL468_RS17720	COG3852	Histidine kinase
AL468_RS17725	COG2204	response regulator
AL468_RS17735	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL468_RS17770	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL468_RS17775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL468_RS17775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL468_RS17785	COG0456	acetyltransferase
AL468_RS17800	COG0084	hydrolase, TatD family'
AL468_RS17810	COG0805	protein transport
AL468_RS17815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL468_RS17825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL468_RS17830	COG3165	ubiquinone biosynthetic process from chorismate
AL468_RS17835	COG2226	methyltransferase
AL468_RS17840	COG1322	Protein conserved in bacteria
AL468_RS17855	COG0628	permease
AL468_RS17890	COG1597	lipid kinase activity
AL468_RS17920	COG2081	HI0933 family
AL468_RS17930	COG1528	Iron-storage protein
AL468_RS17935	COG0589	response to stress
AL468_RS17950	COG0742	ribosomal rna small subunit methyltransferase
AL468_RS17955	COG5002	protein histidine kinase activity
AL468_RS17955	COG5001	Diguanylate cyclase
AL468_RS17960	COG1522	sequence-specific DNA binding
AL468_RS17970	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL468_RS17975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL468_RS17980	COG0583	DNA-binding transcription factor activity
AL468_RS17985	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AL468_RS17990	COG0800	Aldolase
AL468_RS17995	COG2610	gluconate transmembrane transporter activity
AL468_RS18000	COG3265	gluconokinase activity
AL468_RS18005	COG0129	dihydroxy-acid dehydratase activity
AL468_RS18020	COG0583	DNA-binding transcription factor activity
AL468_RS18025	COG1609	Transcriptional regulator
AL468_RS18065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL468_RS18135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL468_RS18140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL468_RS18145	COG2960	long-chain fatty acid transporting porin activity
AL468_RS18150	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL468_RS18155	COG0583	DNA-binding transcription factor activity
AL468_RS18195	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL468_RS18205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL468_RS18210	COG0408	coproporphyrinogen oxidase activity
AL468_RS18215	COG0009	L-threonylcarbamoyladenylate synthase
AL468_RS18220	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL468_RS18225	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL468_RS18230	COG0551	DNA topoisomerase type I activity
AL468_RS18235	COG2922	Belongs to the Smg family
AL468_RS18240	COG0758	DNA mediated transformation
AL468_RS18250	COG0242	peptide deformylase activity
AL468_RS18255	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL468_RS18260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL468_RS18260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL468_RS18265	COG0569	domain protein
AL468_RS18270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL468_RS18280	COG1272	protein, Hemolysin III
AL468_RS18285	COG4326	sporulation control protein
AL468_RS18295	COG3084	Protein conserved in bacteria
AL468_RS18305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AL468_RS18310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL468_RS18315	COG0204	Acyl-transferase
AL468_RS18325	COG0606	chelatase, subunit chli
AL468_RS18335	COG3978	acetolactate synthase activity
AL468_RS18340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL468_RS18345	COG0129	dihydroxy-acid dehydratase activity
AL468_RS18355	COG0583	DNA-binding transcription factor activity
AL468_RS18360	COG2814	Major facilitator Superfamily
AL468_RS18370	COG0765	amino acid transport
AL468_RS18380	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL468_RS18385	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL468_RS18390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL468_RS18395	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL468_RS18400	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL468_RS18405	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL468_RS18415	COG0356	it plays a direct role in the translocation of protons across the membrane
AL468_RS18420	COG3312	ion transport
AL468_RS18425	COG1475	DNA binding
AL468_RS18430	COG1192	Involved in chromosome partitioning
AL468_RS18435	COG0357	Ribosomal RNA small subunit methyltransferase G
AL468_RS18440	COG0445	tRNA wobble uridine modification
AL468_RS18445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL468_RS18455	COG0706	membrane insertase activity
AL468_RS18465	COG0594	ribonuclease P activity
AL468_RS18475	COG1126	abc transporter atp-binding protein
AL468_RS18495	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL468_RS18500	COG0592	DNA-directed DNA polymerase activity
AL468_RS18510	COG0187	DNA topoisomerase II activity
AL468_RS18525	COG0071	Belongs to the small heat shock protein (HSP20) family
AL468_RS18530	COG3977	Valine--pyruvate aminotransferase
AL468_RS18535	COG0366	Alpha amylase catalytic
AL468_RS18540	COG0751	glycine-tRNA ligase activity
AL468_RS18550	COG2119	membrane
AL468_RS18560	COG0425	Belongs to the sulfur carrier protein TusA family
AL468_RS18575	COG0604	alcohol dehydrogenase
AL468_RS18580	COG0183	Belongs to the thiolase family
AL468_RS18590	COG1739	Uncharacterized protein family UPF0029
AL468_RS18595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL468_RS18650	COG2132	Multicopper oxidase
AL468_RS18655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL468_RS18670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL468_RS18690	COG0006	proline dipeptidase activity
AL468_RS18690	COG0006	proline dipeptidase activity
AL468_RS18720	COG3220	belongs to the UPF0276 family
AL468_RS18730	COG0210	DNA helicase
AL468_RS18740	COG0405	Gamma-glutamyltransferase
AL468_RS18745	COG1280	lysine exporter protein (LysE YggA)
AL468_RS18755	COG2962	Rard protein
AL468_RS18760	COG0514	ATP-dependent DNA helicase (RecQ)
AL468_RS18770	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL468_RS18775	COG0248	Ppx GppA phosphatase
AL468_RS18780	COG0513	Belongs to the DEAD box helicase family
AL468_RS18785	COG3118	belongs to the thioredoxin family
AL468_RS18805	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL468_RS18810	COG0633	Ferredoxin
AL468_RS18855	COG3071	HemY protein
AL468_RS18860	COG2959	enzyme of heme biosynthesis
AL468_RS18865	COG1587	Uroporphyrinogen-III synthase
AL468_RS18870	COG0181	hydroxymethylbilane synthase activity
AL468_RS18875	COG3072	Adenylate cyclase
AL468_RS18880	COG1965	Belongs to the frataxin family
AL468_RS18890	COG0019	diaminopimelate decarboxylase activity
AL468_RS18895	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL468_RS18905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AL468_RS18910	COG1011	Hydrolase
AL468_RS18915	COG3287	FIST C domain
AL468_RS18915	COG2200	EAL domain
AL468_RS18915	COG2199	diguanylate cyclase activity
AL468_RS18935	COG0561	phosphatase activity
AL468_RS18940	COG2267	carboxylic ester hydrolase activity
AL468_RS18945	COG1280	lysine exporter protein (LysE YggA)
AL468_RS18950	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AL468_RS18955	COG0640	Transcriptional regulator
AL468_RS18960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL468_RS19010	COG2095	MarC family integral membrane protein
AL468_RS19020	COG0742	ribosomal rna small subunit methyltransferase
AL468_RS19025	COG0552	protein localization to endoplasmic reticulum
AL468_RS19030	COG2884	Cell division ATP-binding protein ftsE
AL468_RS19035	COG2177	Part of the ABC transporter FtsEX involved in
AL468_RS19050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL468_RS19055	COG0705	Rhomboid family
AL468_RS19060	COG1580	Controls the rotational direction of flagella during chemotaxis
AL468_RS19065	COG3161	chorismate lyase activity
AL468_RS19070	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AL468_RS19075	COG2937	Belongs to the GPAT DAPAT family
AL468_RS19085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL468_RS19095	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AL468_RS19100	COG0534	Mate efflux family protein
AL468_RS19105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL468_RS19125	COG4206	TonB-dependent receptor
AL468_RS19170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL468_RS19180	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL468_RS19185	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AL468_RS19185	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AL468_RS19220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL468_RS19230	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL468_RS19235	COG0250	Participates in transcription elongation, termination and antitermination
AL468_RS19250	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL468_RS19255	COG0222	ribosome binding
AL468_RS19260	COG0085	RNA polymerase activity
AL468_RS19265	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL468_RS19270	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AL468_RS19275	COG2816	NAD+ diphosphatase activity
AL468_RS19280	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL468_RS19285	COG1573	uracil-dna glycosylase
AL468_RS19295	COG3068	Protein conserved in bacteria
AL468_RS19300	COG1253	flavin adenine dinucleotide binding
AL468_RS19315	COG0151	Belongs to the GarS family
AL468_RS19325	COG0138	bifunctional purine biosynthesis protein purh
AL468_RS19335	COG0789	Transcriptional regulator
AL468_RS19340	COG3710	Transcriptional regulator
AL468_RS19350	COG0531	amino acid
AL468_RS19355	COG1982	Orn Lys Arg decarboxylase major
AL468_RS19410	COG0488	(ABC) transporter
AL468_RS19420	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AL468_RS19425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL468_RS19430	COG2264	protein methyltransferase activity
AL468_RS19440	COG0439	Biotin carboxylase
AL468_RS19445	COG0511	ligase activity, forming carbon-carbon bonds
AL468_RS19450	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL468_RS19455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL468_RS19470	COG2814	Major facilitator Superfamily
AL468_RS19495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL468_RS19505	COG3263	regulation of cellular component size
AL468_RS19515	COG4232	protein-disulfide reductase activity
AL468_RS19520	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL468_RS19525	COG1027	Aspartate ammonia-lyase
AL468_RS19530	COG3030	protein affecting phage T7 exclusion by the F plasmid
AL468_RS19535	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL468_RS19545	COG2205	protein histidine kinase activity
AL468_RS19550	COG0745	RESPONSE REGULATOR receiver
AL468_RS19555	COG3678	ATP-independent chaperone mediated protein folding
AL468_RS19560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AL468_RS19565	COG0205	6-phosphofructokinase activity
AL468_RS19570	COG0534	Mate efflux family protein
AL468_RS19580	COG0459	protein refolding
AL468_RS19590	COG1285	pathogenesis
AL468_RS19595	COG1509	lysine 2,3-aminomutase activity
AL468_RS19615	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AL468_RS19620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL468_RS19625	COG1053	succinate dehydrogenase
AL468_RS19630	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AL468_RS19650	COG4942	peptidase
AL468_RS19655	COG1045	serine acetyltransferase
AL468_RS19660	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL468_RS19665	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL468_RS19670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL468_RS19675	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AL468_RS19685	COG0471	metal ion transport
AL468_RS19690	COG0688	phosphatidylethanolamine metabolic process
AL468_RS19695	COG1162	GTPase activity
AL468_RS19700	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL468_RS19765	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL468_RS19775	COG0802	atpase or kinase
AL468_RS19785	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL468_RS19790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL468_RS19800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL468_RS19805	COG0330	HflC and HflK could
AL468_RS19810	COG0330	HflC and HflK could
AL468_RS19815	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AL468_RS19820	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL468_RS19830	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AL468_RS19835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL468_RS19835	COG1017	nitric oxide dioxygenase activity
AL468_RS19840	COG1959	2 iron, 2 sulfur cluster binding
AL468_RS19845	COG0557	exoribonuclease II activity
AL468_RS19850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL468_RS19855	COG0546	phosphoglycolate phosphatase activity
AL468_RS19860	COG0180	Tryptophanyl-tRNA synthetase
AL468_RS19875	COG0512	Glutamine amidotransferase of anthranilate synthase
AL468_RS19880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL468_RS19900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL468_RS19905	COG3954	Phosphoribulokinase
AL468_RS19910	COG3089	Belongs to the UPF0270 family
AL468_RS19915	COG0429	hydrolase of the alpha beta-hydrolase fold
AL468_RS19925	COG0488	(ABC) transporter
AL468_RS19930	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL468_RS19945	COG1047	Peptidyl-prolyl cis-trans
AL468_RS19950	COG1446	asparaginase
AL468_RS19965	COG0545	Peptidyl-prolyl cis-trans isomerase
AL468_RS19970	COG2964	Protein conserved in bacteria
AL468_RS19975	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL468_RS19980	COG2923	Belongs to the DsrF TusC family
AL468_RS19985	COG2168	tRNA wobble position uridine thiolation
AL468_RS20000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL468_RS20005	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL468_RS20010	COG2906	2 iron, 2 sulfur cluster binding
AL468_RS20020	COG0281	malic enzyme
AL468_RS20030	COG0626	cystathionine gamma-synthase activity
AL468_RS20035	COG0527	aspartate kinase activity
AL468_RS20035	COG0460	homoserine dehydrogenase
AL468_RS20040	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL468_RS20050	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL468_RS20060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL468_RS20070	COG0137	argininosuccinate synthase activity
AL468_RS20075	COG0165	Argininosuccinate lyase
AL468_RS20075	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL468_RS20090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL468_RS20095	COG0678	peroxiredoxin activity
AL468_RS20095	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL468_RS20110	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL468_RS20140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL468_RS20145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL468_RS20155	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AL468_RS20160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL468_RS20165	COG0360	Binds together with S18 to 16S ribosomal RNA
AL468_RS20170	COG2965	DNA replication, synthesis of RNA primer
AL468_RS20195	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL468_RS20200	COG0432	Pfam Uncharacterised protein family UPF0047
AL468_RS20205	COG0166	Belongs to the GPI family
AL468_RS20215	COG0735	belongs to the Fur family
AL468_RS20220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL468_RS20240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL468_RS20245	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL468_RS20250	COG0175	sulfate reduction
AL468_RS20315	COG0646	methionine synthase
AL468_RS20315	COG1410	methionine synthase
AL468_RS20320	COG0527	aspartate kinase activity
AL468_RS20330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL468_RS20340	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL468_RS20355	COG0629	single-stranded DNA binding
AL468_RS20385	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL468_RS20410	COG2200	EAL domain
AL468_RS20410	COG2199	diguanylate cyclase activity
AL468_RS20430	COG1450	Type ii and iii secretion system protein
AL468_RS20435	COG3267	Type II secretory pathway component ExeA
AL468_RS20435	COG3409	Peptidoglycan-binding domain 1 protein
AL468_RS20445	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL468_RS20450	COG1459	type II secretion system
AL468_RS20495	COG1077	Cell shape determining protein MreB Mrl
AL468_RS20500	COG1792	Involved in formation and maintenance of cell shape
AL468_RS20505	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL468_RS20510	COG0424	maF-like protein
AL468_RS20515	COG1530	ribonuclease E activity
AL468_RS20520	COG3164	Protein of unknown function
AL468_RS20525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL468_RS20530	COG0312	modulator of DNA gyrase
AL468_RS20535	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL468_RS20540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL468_RS20550	COG0564	pseudouridine synthase activity
AL468_RS20555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL468_RS20560	COG3028	Belongs to the UPF0307 family
AL468_RS20565	COG0312	modulator of DNA gyrase
AL468_RS20570	COG2239	Acts as a magnesium transporter
AL468_RS20575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL468_RS20580	COG1660	Displays ATPase and GTPase activities
AL468_RS20585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL468_RS20590	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL468_RS20600	COG1137	ATPase activity
AL468_RS20605	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL468_RS20615	COG0517	IMP dehydrogenase activity
AL468_RS20615	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL468_RS20625	COG1127	ABC transporter
AL468_RS20630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL468_RS20635	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL468_RS20640	COG2854	intermembrane phospholipid transfer
AL468_RS20650	COG5007	Belongs to the BolA IbaG family
AL468_RS20660	COG0204	Acyl-transferase
AL468_RS20665	COG0251	oxidation-reduction process
AL468_RS20670	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AL468_RS20675	COG0540	Belongs to the ATCase OTCase family
AL468_RS20705	COG0456	acetyltransferase
AL468_RS20715	COG0525	valine-tRNA ligase activity
AL468_RS20720	COG2927	DNA polymerase III (CHI subunit)
AL468_RS20730	COG0795	lipopolysaccharide-transporting ATPase activity
AL468_RS20735	COG0795	lipopolysaccharide-transporting ATPase activity
AL468_RS20750	COG1028	Short-chain dehydrogenase reductase Sdr
AL468_RS20760	COG0726	polysaccharide deacetylase
AL468_RS20765	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL468_RS20770	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL468_RS20775	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL468_RS20780	COG1486	melibiose metabolic process
AL468_RS20785	COG3394	polysaccharide catabolic process
AL468_RS20795	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL468_RS20840	COG1012	belongs to the aldehyde dehydrogenase family
AL468_RS20915	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL468_RS20925	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL468_RS20935	COG2066	Belongs to the glutaminase family
AL468_RS20940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL468_RS20945	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL468_RS20955	COG1872	DUF167
AL468_RS20960	COG0762	integral membrane protein
AL468_RS20965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AL468_RS20970	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL468_RS20985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL468_RS20990	COG1678	Uncharacterized ACR, COG1678
AL468_RS20995	COG0189	ligase activity
AL468_RS21000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL468_RS21005	COG2356	endonuclease I
AL468_RS21020	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL468_RS21030	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL468_RS21035	COG0583	DNA-binding transcription factor activity
AL468_RS21040	COG4771	TonB-dependent receptor
AL468_RS21045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL468_RS21050	COG0126	phosphoglycerate kinase activity
AL468_RS21055	COG0191	fructose-bisphosphate aldolase activity
AL468_RS21060	COG0668	transmembrane transport
AL468_RS21075	COG0583	DNA-binding transcription factor activity
AL468_RS21085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL468_RS21090	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AL468_RS21095	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL468_RS21105	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AL468_RS21115	COG3079	Belongs to the UPF0149 family
AL468_RS21120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL468_RS21125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL468_RS21140	COG0354	folic acid binding
AL468_RS21145	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL468_RS21155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL468_RS21165	COG1595	DNA-templated transcription, initiation
AL468_RS21180	COG3086	response to oxidative stress
AL468_RS21185	COG0481	GTPase activity
AL468_RS21190	COG0681	Belongs to the peptidase S26 family
AL468_RS21200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL468_RS21205	COG1381	Involved in DNA repair and RecF pathway recombination
AL468_RS21210	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL468_RS21215	COG0736	holo-[acyl-carrier-protein] synthase activity
AL468_RS21230	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL468_RS21240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL468_RS21245	COG3956	TIGRFAM MazG family protein
AL468_RS21250	COG0504	CTP synthase activity
AL468_RS21255	COG0148	phosphopyruvate hydratase activity
AL468_RS21260	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AL468_RS21265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL468_RS21270	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL468_RS21280	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL468_RS21285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL468_RS21295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL468_RS21300	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL468_RS21305	COG1546	Belongs to the CinA family
AL468_RS21310	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL468_RS21315	COG2137	regulation of response to DNA damage stimulus
AL468_RS21320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL468_RS21325	COG0527	aspartate kinase activity
AL468_RS21390	COG3630	sodium ion export across plasma membrane
AL468_RS21395	COG0511	ligase activity, forming carbon-carbon bonds
AL468_RS21395	COG5016	pyruvate
AL468_RS21400	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AL468_RS21410	COG1238	metal cluster binding
AL468_RS21415	COG0612	Peptidase, M16
AL468_RS21430	COG1854	S-ribosylhomocysteine lyase activity
AL468_RS21435	COG4536	flavin adenine dinucleotide binding
AL468_RS21440	COG4137	Cytochrome C assembly protein
AL468_RS21445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL468_RS21450	COG0228	four-way junction DNA binding
AL468_RS21455	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL468_RS21470	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AL468_RS21475	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL468_RS21480	COG0237	dephospho-CoA kinase activity
AL468_RS21490	COG1459	type II secretion system
AL468_RS21495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL468_RS21500	COG4969	Belongs to the N-Me-Phe pilin family
AL468_RS21510	COG0157	Belongs to the NadC ModD family
AL468_RS21520	COG2186	Transcriptional regulator
AL468_RS21525	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL468_RS21530	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL468_RS21535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL468_RS21550	COG0288	reversible hydration of carbon dioxide
AL468_RS21555	COG0659	secondary active sulfate transmembrane transporter activity
AL468_RS21560	COG1131	(ABC) transporter
AL468_RS21565	COG0842	Transport permease protein
AL468_RS21575	COG1560	Kdo2-lipid A biosynthetic process
AL468_RS21580	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL468_RS21585	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL468_RS21590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL468_RS21600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL468_RS21610	COG1489	DNA binding
AL468_RS21615	COG1643	Atp-dependent helicase
AL468_RS21620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL468_RS21625	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL468_RS21630	COG1049	propionate catabolic process, 2-methylcitrate cycle
AL468_RS21635	COG3112	Uncharacterised protein family (UPF0231)
AL468_RS21640	COG0347	Belongs to the P(II) protein family
AL468_RS21645	COG0004	ammonium transporteR
AL468_RS21650	COG1840	ABC-type Fe3 transport system, periplasmic component
AL468_RS21660	COG3842	ATPase activity
AL468_RS21665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL468_RS21680	COG2971	BadF BadG BcrA BcrD
AL468_RS21690	COG4608	Belongs to the ABC transporter superfamily
AL468_RS21695	COG0444	Belongs to the ABC transporter superfamily
AL468_RS21710	COG0747	negative chemotaxis
AL468_RS21715	COG0784	Response regulator, receiver
AL468_RS21715	COG2205	protein histidine kinase activity
AL468_RS21725	COG0628	permease
AL468_RS21730	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL468_RS21750	COG0739	heme binding
AL468_RS21755	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL468_RS21765	COG2027	D-alanyl-D-alanine carboxypeptidase
AL468_RS21770	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL468_RS21775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL468_RS21780	COG1534	Rna-binding protein
AL468_RS21785	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL468_RS21790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL468_RS21795	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL468_RS21800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL468_RS21810	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL468_RS21825	COG0779	Required for maturation of 30S ribosomal subunits
AL468_RS21830	COG0195	Participates in both transcription termination and antitermination
AL468_RS21835	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL468_RS21840	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL468_RS21845	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL468_RS21850	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL468_RS21855	COG1185	polyribonucleotide nucleotidyltransferase activity
AL468_RS21870	COG0534	Mate efflux family protein
AL468_RS21875	COG0826	peptidase U32
AL468_RS21880	COG0826	peptidase U32
AL468_RS21895	COG3154	lipid carrier protein
AL468_RS21900	COG3153	acetyltransferase
AL468_RS21920	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL468_RS21930	COG0084	hydrolase, TatD family'
AL468_RS21935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL468_RS21950	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AL468_RS21955	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AL468_RS21960	COG0813	purine-nucleoside phosphorylase activity
AL468_RS21970	COG0560	Phosphoserine phosphatase
AL468_RS21980	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AL468_RS21985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL468_RS21990	COG0583	DNA-binding transcription factor activity
AL468_RS22000	COG1022	Amp-dependent synthetase and ligase
AL468_RS22005	COG2169	Transcriptional regulator
AL468_RS22030	COG4964	Belongs to the GSP D family
AL468_RS22090	COG0583	DNA-binding transcription factor activity
AL468_RS22095	COG0531	amino acid
AL468_RS22100	COG2731	YhcH YjgK YiaL family protein
AL468_RS22105	COG3250	beta-galactosidase activity
AL468_RS22110	COG1609	Transcriptional regulator
AL468_RS22120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL468_RS22125	COG1085	galactose-1-phosphate uridylyltransferase
AL468_RS22130	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AL468_RS22135	COG2017	converts alpha-aldose to the beta-anomer
AL468_RS22150	COG2176	DNA-directed DNA polymerase activity
AL468_RS22155	COG1609	Transcriptional regulator
AL468_RS22160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL468_RS22185	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL468_RS22190	COG1349	DNA-binding transcription factor activity
AL468_RS22195	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL468_RS22200	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL468_RS22210	COG2271	Major facilitator Superfamily
AL468_RS22215	COG0584	glycerophosphoryl diester phosphodiesterase
AL468_RS22220	COG2171	N-acyltransferase activity
AL468_RS22225	COG3141	response to X-ray
AL468_RS22245	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL468_RS22255	COG1074	ATP-dependent DNA helicase activity
AL468_RS22260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL468_RS22285	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL468_RS22285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL468_RS22300	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL468_RS22305	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL468_RS22310	COG2166	iron-sulfur cluster assembly
AL468_RS22315	COG3706	GGDEF domain
AL468_RS22320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL468_RS22325	COG0693	protein deglycase activity
AL468_RS22330	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL468_RS22355	COG1595	DNA-templated transcription, initiation
AL468_RS22375	COG3056	Lipoprotein
AL468_RS22380	COG2813	Specifically methylates the guanine in position
AL468_RS22385	COG0271	Belongs to the BolA IbaG family
AL468_RS22395	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL468_RS22400	COG1805	sodium ion transport
AL468_RS22405	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL468_RS22410	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL468_RS22415	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL468_RS22420	COG2871	sodium ion transport
AL468_RS22425	COG1477	protein flavinylation
AL468_RS22440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL468_RS22445	COG0514	ATP-dependent DNA helicase (RecQ)
AL468_RS22450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL468_RS22465	COG0733	neurotransmitter:sodium symporter activity
AL468_RS22485	COG0442	prolyl-tRNA aminoacylation
AL468_RS22490	COG1720	tRNA m6t6A37 methyltransferase activity
AL468_RS22495	COG0254	rRNA binding
AL468_RS22505	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL468_RS22530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL468_RS22535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL468_RS22570	COG0564	pseudouridine synthase activity
AL468_RS22580	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL468_RS22585	COG0024	Methionine aminopeptidase
AL468_RS22590	COG0052	Belongs to the universal ribosomal protein uS2 family
AL468_RS22595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL468_RS22600	COG0528	UMP kinase activity
AL468_RS22605	COG0233	cytoplasmic translational termination
AL468_RS22610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL468_RS22615	COG0575	Belongs to the CDS family
AL468_RS22620	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL468_RS22625	COG0750	zinc metalloprotease
AL468_RS22635	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL468_RS22640	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL468_RS22650	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL468_RS22655	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL468_RS22665	COG0587	DNA-directed DNA polymerase activity
AL468_RS22670	COG0825	malonyl-CoA metabolic process
AL468_RS22685	COG0347	Belongs to the P(II) protein family
AL468_RS22690	COG3021	interspecies interaction between organisms
AL468_RS22700	COG0741	lytic transglycosylase activity
AL468_RS22700	COG1388	LysM domain
AL468_RS22705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL468_RS22710	COG2226	methyltransferase
AL468_RS22715	COG0328	RNA-DNA hybrid ribonuclease activity
AL468_RS22750	COG1960	acyl-CoA dehydrogenase activity
AL468_RS22755	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL468_RS22760	COG0121	glutamine amidotransferase
AL468_RS22765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL468_RS22770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL468_RS22775	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL468_RS22780	COG2233	PERMEase
AL468_RS22800	COG4783	chaperone-mediated protein folding
AL468_RS22815	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL468_RS22825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL468_RS22845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL468_RS22850	COG1393	Belongs to the ArsC family
AL468_RS22875	COG2837	iron assimilation
AL468_RS22880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL468_RS22890	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL468_RS22895	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL468_RS22900	COG1334	flagellar protein FlaG
AL468_RS22905	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL468_RS22915	COG1516	flagellar protein fliS
AL468_RS22925	COG4191	Histidine kinase
AL468_RS22935	COG1677	Flagellar hook-basal body complex protein FliE
AL468_RS22945	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL468_RS22995	COG1987	bacterial-type flagellum assembly
AL468_RS23000	COG1684	flagellar biosynthetic protein fliR
AL468_RS23035	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL468_RS23040	COG0784	Response regulator, receiver
AL468_RS23040	COG2198	Histidine kinase
AL468_RS23040	COG0643	Histidine kinase
AL468_RS23045	COG2201	protein-glutamate methylesterase activity
AL468_RS23050	COG1192	Involved in chromosome partitioning
AL468_RS23060	COG0835	chemotaxis
AL468_RS23070	COG4133	protoheme IX ABC transporter activity
AL468_RS23075	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL468_RS23080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL468_RS23085	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL468_RS23090	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL468_RS23095	COG1138	Cytochrome C-type biogenesis protein
AL468_RS23100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL468_RS23110	COG4235	cytochrome complex assembly
AL468_RS23110	COG3088	subunit of a heme lyase
AL468_RS23140	COG0183	Belongs to the thiolase family
AL468_RS23145	COG1024	Enoyl-CoA hydratase
AL468_RS23145	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL468_RS23160	COG2062	phosphohistidine phosphatase, SixA
AL468_RS23165	COG2840	Smr protein MutS2
AL468_RS23170	COG2890	protein-(glutamine-N5) methyltransferase activity
AL468_RS23175	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL468_RS23180	COG2860	membrane
AL468_RS23190	COG3101	peptidyl-lysine hydroxylation
AL468_RS23205	COG0431	NADPH-dependent FMN reductase
AL468_RS23210	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL468_RS23210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL468_RS23215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL468_RS23225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL468_RS23230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL468_RS23240	COG0101	tRNA pseudouridine synthase activity
AL468_RS23250	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL468_RS23255	COG0285	dihydrofolate synthase activity
AL468_RS23260	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AL468_RS23265	COG1286	toxin biosynthetic process
AL468_RS23270	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL468_RS23275	COG0583	DNA-binding transcription factor activity
AL468_RS23280	COG0745	RESPONSE REGULATOR receiver
AL468_RS23290	COG2832	Protein of unknown function (DUF454)
AL468_RS23295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL468_RS23310	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AL468_RS23315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL468_RS23320	COG0814	amino acid
AL468_RS23325	COG0251	oxidation-reduction process
AL468_RS23330	COG3681	Belongs to the UPF0597 family
AL468_RS23345	COG2261	transglycosylase associated protein
AL468_RS23350	COG2983	Belongs to the UPF0260 family
AL468_RS23355	COG0668	transmembrane transport
AL468_RS23360	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL468_RS23365	COG0346	lactoylglutathione lyase activity
AL468_RS23375	COG1785	Belongs to the alkaline phosphatase family
AL468_RS23395	COG2226	methyltransferase
AL468_RS23410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL468_RS23415	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL468_RS23425	COG3139	Protein of unknown function (DUF1315)
AL468_RS23430	COG0252	asparaginase activity
AL468_RS23435	COG0616	signal peptide processing
AL468_RS23440	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL468_RS23440	COG1902	pentaerythritol trinitrate reductase activity
AL468_RS23450	COG0778	Nitroreductase
AL468_RS23455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL468_RS23470	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL468_RS23485	COG3082	Protein of unknown function (DUF1414)
AL468_RS23490	COG3081	Nucleoid-associated protein
AL468_RS23505	COG1757	Na H antiporter
AL468_RS23510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL468_RS23515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL468_RS23520	COG2095	MarC family integral membrane protein
AL468_RS23525	COG1012	belongs to the aldehyde dehydrogenase family
AL468_RS23525	COG1454	alcohol dehydrogenase
AL468_RS23545	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL468_RS23550	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AL468_RS23645	COG4695	Portal protein
AL468_RS23780	COG2056	Na+-H+ antiporter family
AL468_RS23785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL468_RS23795	COG2885	chlorophyll binding
AL468_RS23805	COG0346	lactoylglutathione lyase activity
AL468_RS23810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL468_RS23815	COG4660	Part of a membrane complex involved in electron transport
AL468_RS23820	COG4659	FMN binding
AL468_RS23825	COG4658	electron transport chain
AL468_RS23830	COG4656	Part of a membrane complex involved in electron transport
AL468_RS23835	COG2878	Part of a membrane complex involved in electron transport
AL468_RS23840	COG4657	Part of a membrane complex involved in electron transport
AL468_RS23855	COG0556	nucleotide-excision repair
AL468_RS23860	COG2204	response regulator
AL468_RS23865	COG2198	Histidine kinase
AL468_RS23870	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AL468_RS23875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL468_RS23880	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL468_RS23885	COG0315	cyclic pyranopterin monophosphate synthase activity
AL468_RS23890	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL468_RS23895	COG0314	molybdopterin synthase activity
AL468_RS23905	COG0601	transmembrane transport
AL468_RS23910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL468_RS23915	COG0444	Belongs to the ABC transporter superfamily
AL468_RS23925	COG0435	Glutathione S-transferase
AL468_RS23935	COG3174	membrane
AL468_RS23940	COG0280	phosphate acetyltransferase
AL468_RS23940	COG0857	belongs to the CobB CobQ family
AL468_RS23945	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL468_RS23950	COG3092	negative regulation of chromosome organization
AL468_RS23960	COG4120	Belongs to the binding-protein-dependent transport system permease family
AL468_RS23965	COG1122	ATPase activity
AL468_RS23970	COG0366	Alpha amylase catalytic
AL468_RS23975	COG3706	GGDEF domain
AL468_RS23980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL468_RS23985	COG0653	protein targeting
AL468_RS23990	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL468_RS23995	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL468_RS24000	COG2186	Transcriptional regulator
AL468_RS24010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL468_RS24010	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL468_RS24020	COG0572	uridine kinase
AL468_RS24030	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AL468_RS24035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL468_RS24040	COG0659	secondary active sulfate transmembrane transporter activity
AL468_RS24050	COG1530	ribonuclease E activity
AL468_RS24055	COG0564	pseudouridine synthase activity
AL468_RS24060	COG0424	maF-like protein
AL468_RS24065	COG1399	metal-binding, possibly nucleic acid-binding protein
AL468_RS24075	COG0416	fatty acid biosynthetic process
AL468_RS24080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL468_RS24110	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL468_RS24115	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL468_RS24120	COG0470	DNA polymerase III
AL468_RS24125	COG0084	hydrolase, TatD family'
AL468_RS24130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL468_RS24130	COG1263	PTS System
AL468_RS24145	COG0733	neurotransmitter:sodium symporter activity
AL468_RS24160	COG4667	esterase of the alpha-beta hydrolase superfamily
AL468_RS24165	COG0469	pyruvate kinase activity
AL468_RS24170	COG1940	carbohydrate kinase activity
AL468_RS24175	COG0784	Response regulator, receiver
AL468_RS24175	COG0835	chemotaxis
AL468_RS24180	COG0587	DNA-directed DNA polymerase activity
AL468_RS24195	COG1028	Short-chain dehydrogenase reductase Sdr
AL468_RS24200	COG0616	signal peptide processing
AL468_RS24205	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL468_RS24210	COG0539	negative regulation of cytoplasmic translation
AL468_RS24220	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AL468_RS24225	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL468_RS24235	COG4166	transmembrane transport
AL468_RS24250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL468_RS24250	COG3008	intermembrane lipid transfer
AL468_RS24255	COG2995	paraquat-inducible protein a
AL468_RS24260	COG3258	Cytochrome c
AL468_RS24265	COG2863	cytochrome
AL468_RS24300	COG4232	protein-disulfide reductase activity
AL468_RS24305	COG3118	belongs to the thioredoxin family
AL468_RS24335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL468_RS24345	COG0577	efflux transmembrane transporter activity
AL468_RS24345	COG1136	(ABC) transporter
AL468_RS24355	COG1136	(ABC) transporter
AL468_RS24355	COG0577	efflux transmembrane transporter activity
AL468_RS24410	COG3850	Histidine kinase
AL468_RS24410	COG5002	protein histidine kinase activity
AL468_RS24415	COG0745	RESPONSE REGULATOR receiver
AL468_RS24425	COG0840	transmembrane signaling receptor activity
AL468_RS24440	COG1032	radical SAM domain protein
AL468_RS24445	COG5001	Diguanylate cyclase
AL468_RS24460	COG0583	DNA-binding transcription factor activity
AL468_RS24465	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL468_RS24475	COG2350	Protein conserved in bacteria
AL468_RS24485	COG2917	probably involved in intracellular septation
AL468_RS24505	COG1301	dicarboxylic acid transport
AL468_RS24515	COG0318	PFAM AMP-dependent synthetase and ligase
AL468_RS24520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL468_RS24525	COG0159	tryptophan synthase activity
AL468_RS24535	COG0135	phosphoribosylanthranilate isomerase activity
AL468_RS24535	COG0134	indole-3-glycerol-phosphate synthase activity
AL468_RS24545	COG0512	Glutamine amidotransferase of anthranilate synthase
AL468_RS24550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL468_RS24560	COG0613	PHP domain protein
AL468_RS24565	COG0009	L-threonylcarbamoyladenylate synthase
AL468_RS24575	COG1187	pseudouridine synthase activity
AL468_RS24595	COG0417	DNA replication proofreading
AL468_RS24600	COG2197	response regulator
AL468_RS24605	COG0322	excinuclease ABC activity
AL468_RS24645	COG0019	diaminopimelate decarboxylase activity
AL468_RS24675	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL468_RS24680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL468_RS24700	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AL468_RS24710	COG0437	4 iron, 4 sulfur cluster binding
AL468_RS24715	COG3301	Polysulphide reductase, NrfD
AL468_RS24720	COG1138	Cytochrome C-type biogenesis protein
AL468_RS24730	COG3088	subunit of a heme lyase
AL468_RS24730	COG4235	cytochrome complex assembly
AL468_RS24740	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL468_RS24765	COG2989	Protein conserved in bacteria
AL468_RS24770	COG3108	Peptidase M15
AL468_RS24775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL468_RS24790	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL468_RS24820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL468_RS24825	COG0840	transmembrane signaling receptor activity
AL468_RS25015	COG1393	Belongs to the ArsC family