locus-tag	class	description
HOO69_RS00070	COG1410	methionine synthase
HOO69_RS00070	COG0646	methionine synthase
HOO69_RS00075	COG2239	Acts as a magnesium transporter
HOO69_RS00080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HOO69_RS00085	COG1660	Displays ATPase and GTPase activities
HOO69_RS00090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HOO69_RS00095	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HOO69_RS00105	COG1137	ATPase activity
HOO69_RS00110	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HOO69_RS00120	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HOO69_RS00125	COG0517	IMP dehydrogenase activity
HOO69_RS00125	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HOO69_RS00135	COG1127	ABC transporter
HOO69_RS00140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HOO69_RS00145	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HOO69_RS00150	COG2854	intermembrane phospholipid transfer
HOO69_RS00155	COG3113	response to antibiotic
HOO69_RS00160	COG5007	Belongs to the BolA IbaG family
HOO69_RS00170	COG0204	Acyl-transferase
HOO69_RS00235	COG0741	lytic transglycosylase activity
HOO69_RS00240	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HOO69_RS00245	COG1194	a g-specific adenine glycosylase
HOO69_RS00250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HOO69_RS00255	COG2066	Belongs to the glutaminase family
HOO69_RS00260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HOO69_RS00265	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HOO69_RS00280	COG0762	integral membrane protein
HOO69_RS00285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HOO69_RS00290	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HOO69_RS00310	COG1918	ferrous iron import across plasma membrane
HOO69_RS00310	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HOO69_RS00335	COG1131	(ABC) transporter
HOO69_RS00345	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HOO69_RS00350	COG1678	Uncharacterized ACR, COG1678
HOO69_RS00355	COG0189	ligase activity
HOO69_RS00360	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HOO69_RS00365	COG2356	endonuclease I
HOO69_RS00380	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HOO69_RS00385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HOO69_RS00395	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HOO69_RS00405	COG0191	fructose-bisphosphate aldolase activity
HOO69_RS00410	COG0668	transmembrane transport
HOO69_RS00425	COG0583	DNA-binding transcription factor activity
HOO69_RS00435	COG3706	GGDEF domain
HOO69_RS00450	COG1349	DNA-binding transcription factor activity
HOO69_RS00455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HOO69_RS00460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HOO69_RS00465	COG3722	fumarate hydratase activity
HOO69_RS00470	COG0246	Mannitol dehydrogenase
HOO69_RS00475	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HOO69_RS00475	COG2213	PTS system mannitol-specific
HOO69_RS00480	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HOO69_RS00490	COG0142	geranyltranstransferase activity
HOO69_RS00495	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HOO69_RS00505	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HOO69_RS00510	COG3610	response to peptide
HOO69_RS00540	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HOO69_RS00550	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HOO69_RS00555	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HOO69_RS00560	COG0582	viral genome integration into host DNA
HOO69_RS00640	COG0358	DNA primase activity
HOO69_RS00645	COG1610	YqeY-like protein
HOO69_RS00650	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HOO69_RS00655	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HOO69_RS00660	COG2267	carboxylic ester hydrolase activity
HOO69_RS00670	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HOO69_RS00675	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HOO69_RS00685	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HOO69_RS00690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HOO69_RS00695	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HOO69_RS00700	COG0585	pseudouridine synthase activity
HOO69_RS00720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOO69_RS00725	COG4536	flavin adenine dinucleotide binding
HOO69_RS00730	COG4137	Cytochrome C assembly protein
HOO69_RS00735	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HOO69_RS00745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HOO69_RS00760	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HOO69_RS00765	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HOO69_RS00770	COG0237	dephospho-CoA kinase activity
HOO69_RS00780	COG1459	type II secretion system
HOO69_RS00785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HOO69_RS00795	COG0157	Belongs to the NadC ModD family
HOO69_RS00805	COG0716	FMN binding
HOO69_RS00810	COG4974	Belongs to the 'phage' integrase family
HOO69_RS00815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HOO69_RS00820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HOO69_RS00825	COG2186	Transcriptional regulator
HOO69_RS00830	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HOO69_RS00835	COG0508	dehydrogenase complex catalyzes the overall conversion of
HOO69_RS00840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HOO69_RS00855	COG0288	reversible hydration of carbon dioxide
HOO69_RS00860	COG0659	secondary active sulfate transmembrane transporter activity
HOO69_RS00865	COG1131	(ABC) transporter
HOO69_RS00870	COG0842	Transport permease protein
HOO69_RS00885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HOO69_RS00900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HOO69_RS00910	COG1643	Atp-dependent helicase
HOO69_RS00915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HOO69_RS00920	COG1752	Esterase of the alpha-beta hydrolase superfamily
HOO69_RS00930	COG3112	Uncharacterised protein family (UPF0231)
HOO69_RS00940	COG0004	ammonium transporteR
HOO69_RS00945	COG1840	ABC-type Fe3 transport system, periplasmic component
HOO69_RS00955	COG3842	ATPase activity
HOO69_RS00960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HOO69_RS00975	COG2971	BadF BadG BcrA BcrD
HOO69_RS00985	COG4608	Belongs to the ABC transporter superfamily
HOO69_RS00990	COG0444	Belongs to the ABC transporter superfamily
HOO69_RS00995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOO69_RS01005	COG0747	negative chemotaxis
HOO69_RS01010	COG2205	protein histidine kinase activity
HOO69_RS01010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HOO69_RS01010	COG0784	Response regulator, receiver
HOO69_RS01010	COG2198	Histidine kinase
HOO69_RS01015	COG2813	Specifically methylates the guanine in position
HOO69_RS01020	COG0628	permease
HOO69_RS01025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HOO69_RS01045	COG0739	heme binding
HOO69_RS01050	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HOO69_RS01060	COG2027	D-alanyl-D-alanine carboxypeptidase
HOO69_RS01065	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HOO69_RS01070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HOO69_RS01075	COG1534	Rna-binding protein
HOO69_RS01085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HOO69_RS01090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HOO69_RS01105	COG0456	acetyltransferase
HOO69_RS01115	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HOO69_RS01120	COG0513	Belongs to the DEAD box helicase family
HOO69_RS01125	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HOO69_RS01140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HOO69_RS01145	COG2204	response regulator
HOO69_RS01155	COG0667	Aldo Keto reductase
HOO69_RS01165	COG3066	DNA modification
HOO69_RS01180	COG0730	response to heat
HOO69_RS01190	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HOO69_RS01195	COG1283	sodium-dependent phosphate transmembrane transporter activity
HOO69_RS01200	COG0583	DNA-binding transcription factor activity
HOO69_RS01205	COG0640	Transcriptional regulator
HOO69_RS01210	COG0268	Binds directly to 16S ribosomal RNA
HOO69_RS01215	COG0728	peptidoglycan biosynthetic process
HOO69_RS01220	COG0196	riboflavin kinase activity
HOO69_RS01235	COG1047	Peptidyl-prolyl cis-trans
HOO69_RS01240	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HOO69_RS01245	COG0612	Peptidase, M16
HOO69_RS01250	COG1966	Carbon starvation protein
HOO69_RS01260	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HOO69_RS01275	COG3279	Response regulator of the LytR AlgR family
HOO69_RS01280	COG3275	phosphorelay sensor kinase activity
HOO69_RS01285	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HOO69_RS01290	COG0287	Prephenate dehydrogenase
HOO69_RS01290	COG1605	Chorismate mutase
HOO69_RS01295	COG0739	heme binding
HOO69_RS01305	COG0488	(ABC) transporter
HOO69_RS01315	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
HOO69_RS01320	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HOO69_RS01330	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HOO69_RS01335	COG0077	Prephenate dehydratase
HOO69_RS01335	COG1605	Chorismate mutase
HOO69_RS01340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HOO69_RS01345	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HOO69_RS01350	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HOO69_RS01355	COG0564	pseudouridine synthase activity
HOO69_RS01365	COG0542	response to heat
HOO69_RS01405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOO69_RS01410	COG0483	inositol monophosphate 1-phosphatase activity
HOO69_RS01425	COG1104	cysteine desulfurase activity
HOO69_RS01430	COG0822	iron-sulfur transferase activity
HOO69_RS01450	COG0633	Ferredoxin
HOO69_RS01455	COG2975	iron-sulfur cluster assembly
HOO69_RS01460	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HOO69_RS01470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HOO69_RS01475	COG0583	DNA-binding transcription factor activity
HOO69_RS01485	COG0583	DNA-binding transcription factor activity
HOO69_RS01490	COG1022	Amp-dependent synthetase and ligase
HOO69_RS01495	COG2169	Transcriptional regulator
HOO69_RS01525	COG4964	Belongs to the GSP D family
HOO69_RS01565	COG0583	DNA-binding transcription factor activity
HOO69_RS01575	COG1175	transmembrane transport
HOO69_RS01580	COG0395	ABC-type sugar transport system, permease component
HOO69_RS01585	COG1653	transport
HOO69_RS01590	COG3250	beta-galactosidase activity
HOO69_RS01600	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HOO69_RS01600	COG3408	Glycogen debranching enzyme
HOO69_RS01605	COG0662	Cupin 2, conserved barrel domain protein
HOO69_RS01605	COG2207	Transcriptional regulator
HOO69_RS01630	COG0531	amino acid
HOO69_RS01635	COG2731	YhcH YjgK YiaL family protein
HOO69_RS01640	COG3250	beta-galactosidase activity
HOO69_RS01645	COG1609	Transcriptional regulator
HOO69_RS01650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HOO69_RS01655	COG1085	galactose-1-phosphate uridylyltransferase
HOO69_RS01665	COG2017	converts alpha-aldose to the beta-anomer
HOO69_RS01685	COG0583	DNA-binding transcription factor activity
HOO69_RS01690	COG4989	oxidoreductase activity
HOO69_RS01700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOO69_RS01715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HOO69_RS01720	COG1349	DNA-binding transcription factor activity
HOO69_RS01725	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HOO69_RS01730	COG2271	Major facilitator Superfamily
HOO69_RS01735	COG2171	N-acyltransferase activity
HOO69_RS01740	COG0450	alkyl hydroperoxide reductase
HOO69_RS01745	COG0583	DNA-binding transcription factor activity
HOO69_RS01750	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HOO69_RS01760	COG0517	IMP dehydrogenase activity
HOO69_RS01765	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HOO69_RS01775	COG1862	Preprotein translocase
HOO69_RS01780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HOO69_RS01785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HOO69_RS01795	COG1879	ABC-type sugar transport system periplasmic component
HOO69_RS01810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HOO69_RS01825	COG0745	RESPONSE REGULATOR receiver
HOO69_RS01830	COG5002	protein histidine kinase activity
HOO69_RS01840	COG0248	Ppx GppA phosphatase
HOO69_RS01845	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HOO69_RS01850	COG0573	inorganic phosphate transmembrane transporter activity
HOO69_RS01855	COG0581	inorganic phosphate transmembrane transporter activity
HOO69_RS01860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HOO69_RS01865	COG0704	Plays a role in the regulation of phosphate uptake
HOO69_RS01890	COG3142	Participates in the control of copper homeostasis
HOO69_RS01895	COG3141	response to X-ray
HOO69_RS01900	COG1309	transcriptional regulator
HOO69_RS01905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HOO69_RS01925	COG3284	Transcriptional regulator
HOO69_RS01930	COG3842	ATPase activity
HOO69_RS01935	COG3842	ATPase activity
HOO69_RS01945	COG0395	ABC-type sugar transport system, permease component
HOO69_RS01960	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HOO69_RS01965	COG1074	ATP-dependent DNA helicase activity
HOO69_RS01970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HOO69_RS01990	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HOO69_RS01995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HOO69_RS02000	COG2166	iron-sulfur cluster assembly
HOO69_RS02015	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HOO69_RS02020	COG0124	histidyl-tRNA synthetase
HOO69_RS02025	COG2976	Protein conserved in bacteria
HOO69_RS02030	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HOO69_RS02035	COG1160	GTP binding
HOO69_RS02045	COG3706	GGDEF domain
HOO69_RS02060	COG0516	GMP reductase activity
HOO69_RS02060	COG0517	IMP dehydrogenase activity
HOO69_RS02065	COG0519	Catalyzes the synthesis of GMP from XMP
HOO69_RS02065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HOO69_RS02075	COG1584	GPR1 FUN34 yaaH family protein
HOO69_RS02080	COG1115	amino acid carrier protein
HOO69_RS02110	COG2873	o-acetylhomoserine
HOO69_RS02115	COG1253	flavin adenine dinucleotide binding
HOO69_RS02120	COG0583	DNA-binding transcription factor activity
HOO69_RS02130	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HOO69_RS02135	COG0204	Acyl-transferase
HOO69_RS02140	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HOO69_RS02155	COG0668	transmembrane transport
HOO69_RS02175	COG0009	L-threonylcarbamoyladenylate synthase
HOO69_RS02180	COG0579	oxidoreductase
HOO69_RS02185	COG1473	amidohydrolase
HOO69_RS02195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HOO69_RS02215	COG2271	Major facilitator Superfamily
HOO69_RS02220	COG3851	Histidine kinase
HOO69_RS02225	COG2197	response regulator
HOO69_RS02250	COG2867	negative regulation of translational initiation
HOO69_RS02255	COG2914	Belongs to the UPF0125 (RnfH) family
HOO69_RS02260	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HOO69_RS02265	COG0497	DNA recombination
HOO69_RS02275	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HOO69_RS02280	COG1301	dicarboxylic acid transport
HOO69_RS02295	COG0443	Heat shock 70 kDa protein
HOO69_RS02300	COG0484	heat shock protein binding
HOO69_RS02330	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HOO69_RS02345	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HOO69_RS02350	COG0047	phosphoribosylformylglycinamidine synthase activity
HOO69_RS02350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOO69_RS02375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HOO69_RS02380	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HOO69_RS02385	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HOO69_RS02395	COG2840	Smr protein MutS2
HOO69_RS02425	COG3104	oligopeptide transport
HOO69_RS02430	COG0367	asparagine synthase
HOO69_RS02435	COG4651	solute:proton antiporter activity
HOO69_RS02435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HOO69_RS02440	COG1846	Transcriptional regulator
HOO69_RS02440	COG1940	carbohydrate kinase activity
HOO69_RS02445	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HOO69_RS02450	COG1263	PTS System
HOO69_RS02450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HOO69_RS02450	COG2190	(PTS) system
HOO69_RS02455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HOO69_RS02460	COG0735	belongs to the Fur family
HOO69_RS02470	COG0716	FMN binding
HOO69_RS02480	COG0596	Alpha beta hydrolase
HOO69_RS02485	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HOO69_RS02490	COG0033	Phosphoglucomutase
HOO69_RS02500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HOO69_RS02515	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HOO69_RS02520	COG1053	succinate dehydrogenase
HOO69_RS02530	COG0567	Dehydrogenase, E1 component
HOO69_RS02535	COG0508	dehydrogenase complex catalyzes the overall conversion of
HOO69_RS02570	COG3098	single-species biofilm formation
HOO69_RS02575	COG0564	pseudouridine synthase activity
HOO69_RS02585	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HOO69_RS02590	COG0142	geranyltranstransferase activity
HOO69_RS02600	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HOO69_RS02610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HOO69_RS02610	COG0301	tRNA thio-modification
HOO69_RS02615	COG0583	DNA-binding transcription factor activity
HOO69_RS02625	COG2363	Small membrane protein
HOO69_RS02630	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
HOO69_RS02640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOO69_RS02645	COG1611	Belongs to the LOG family
HOO69_RS02660	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HOO69_RS02660	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HOO69_RS02680	COG1876	peptidase activity
HOO69_RS02685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HOO69_RS02690	COG1393	Belongs to the ArsC family
HOO69_RS02710	COG4235	cytochrome complex assembly
HOO69_RS02715	COG4221	oxidoreductase activity
HOO69_RS02720	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HOO69_RS02730	COG0437	4 iron, 4 sulfur cluster binding
HOO69_RS02735	COG3301	Polysulphide reductase, NrfD
HOO69_RS02740	COG1138	Cytochrome C-type biogenesis protein
HOO69_RS02745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HOO69_RS02750	COG4235	cytochrome complex assembly
HOO69_RS02750	COG3088	subunit of a heme lyase
HOO69_RS02765	COG2837	iron assimilation
HOO69_RS02780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HOO69_RS02790	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HOO69_RS02800	COG1516	flagellar protein fliS
HOO69_RS02810	COG4191	Histidine kinase
HOO69_RS02820	COG1677	Flagellar hook-basal body complex protein FliE
HOO69_RS02830	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HOO69_RS02855	COG1580	Controls the rotational direction of flagella during chemotaxis
HOO69_RS02880	COG1987	bacterial-type flagellum assembly
HOO69_RS02885	COG1684	flagellar biosynthetic protein fliR
HOO69_RS02900	COG2890	protein-(glutamine-N5) methyltransferase activity
HOO69_RS02905	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HOO69_RS02910	COG0737	Belongs to the 5'-nucleotidase family
HOO69_RS02920	COG2860	membrane
HOO69_RS02925	COG3101	peptidyl-lysine hydroxylation
HOO69_RS02945	COG0431	NADPH-dependent FMN reductase
HOO69_RS02955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HOO69_RS02960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HOO69_RS02965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HOO69_RS02975	COG0101	tRNA pseudouridine synthase activity
HOO69_RS02980	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HOO69_RS02985	COG0285	dihydrofolate synthase activity
HOO69_RS02990	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HOO69_RS02995	COG1286	toxin biosynthetic process
HOO69_RS03000	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HOO69_RS03005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HOO69_RS03010	COG1121	(ABC) transporter
HOO69_RS03015	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HOO69_RS03020	COG4977	sequence-specific DNA binding
HOO69_RS03030	COG1918	ferrous iron import across plasma membrane
HOO69_RS03035	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HOO69_RS03050	COG0018	arginyl-trna synthetase
HOO69_RS03060	COG3102	Protein conserved in bacteria
HOO69_RS03070	COG2062	phosphohistidine phosphatase, SixA
HOO69_RS03100	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HOO69_RS03105	COG2198	Histidine kinase
HOO69_RS03105	COG0784	Response regulator, receiver
HOO69_RS03105	COG0643	Histidine kinase
HOO69_RS03115	COG1192	Involved in chromosome partitioning
HOO69_RS03125	COG0835	chemotaxis
HOO69_RS03135	COG4133	protoheme IX ABC transporter activity
HOO69_RS03145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HOO69_RS03150	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HOO69_RS03155	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
HOO69_RS03160	COG1138	Cytochrome C-type biogenesis protein
HOO69_RS03165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HOO69_RS03170	COG4235	cytochrome complex assembly
HOO69_RS03170	COG3088	subunit of a heme lyase
HOO69_RS03185	COG2067	long-chain fatty acid transport protein
HOO69_RS03190	COG2067	long-chain fatty acid transport protein
HOO69_RS03205	COG0183	Belongs to the thiolase family
HOO69_RS03210	COG1024	Enoyl-CoA hydratase
HOO69_RS03210	COG1250	3-hydroxyacyl-CoA dehydrogenase
HOO69_RS03215	COG0778	Nitroreductase
HOO69_RS03225	COG0745	RESPONSE REGULATOR receiver
HOO69_RS03230	COG2832	Protein of unknown function (DUF454)
HOO69_RS03235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HOO69_RS03250	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HOO69_RS03345	COG2983	Belongs to the UPF0260 family
HOO69_RS03370	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HOO69_RS03370	COG2755	lipolytic protein G-D-S-L family
HOO69_RS03375	COG0668	transmembrane transport
HOO69_RS03410	COG2226	methyltransferase
HOO69_RS03425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HOO69_RS03430	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOO69_RS03440	COG3139	Protein of unknown function (DUF1315)
HOO69_RS03445	COG3012	SEC-C Motif Domain Protein
HOO69_RS03450	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HOO69_RS03460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HOO69_RS03465	COG0215	cysteine-tRNA ligase activity
HOO69_RS03475	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HOO69_RS03480	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
HOO69_RS03505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HOO69_RS03515	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HOO69_RS03540	COG3070	regulator of competence-specific genes
HOO69_RS03545	COG1609	Transcriptional regulator
HOO69_RS03555	COG0745	RESPONSE REGULATOR receiver
HOO69_RS03560	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HOO69_RS03565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HOO69_RS03575	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HOO69_RS03580	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HOO69_RS03595	COG0318	PFAM AMP-dependent synthetase and ligase
HOO69_RS03615	COG4067	protein conserved in archaea
HOO69_RS03615	COG0189	ligase activity
HOO69_RS03630	COG1801	Protein of unknown function DUF72
HOO69_RS03640	COG1187	pseudouridine synthase activity
HOO69_RS03650	COG1278	Cold shock
HOO69_RS03660	COG0542	response to heat
HOO69_RS03695	COG2116	formate transmembrane transporter activity
HOO69_RS03705	COG0390	transport system, permease component
HOO69_RS03710	COG4459	periplasmic nitrate reductase
HOO69_RS03715	COG3005	denitrification pathway
HOO69_RS03720	COG0243	molybdopterin cofactor binding
HOO69_RS03755	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HOO69_RS03760	COG0840	transmembrane signaling receptor activity
HOO69_RS03765	COG0632	four-way junction helicase activity
HOO69_RS03770	COG2255	four-way junction helicase activity
HOO69_RS03780	COG1294	oxidase, subunit
HOO69_RS03785	COG4890	Cyd operon protein YbgT
HOO69_RS03795	COG0824	Thioesterase
HOO69_RS03800	COG0811	peptide transport
HOO69_RS03820	COG2885	chlorophyll binding
HOO69_RS03825	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HOO69_RS03830	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HOO69_RS03835	COG0137	argininosuccinate synthase activity
HOO69_RS03845	COG2205	protein histidine kinase activity
HOO69_RS03845	COG0784	Response regulator, receiver
HOO69_RS03875	COG0270	DNA (cytosine-5-)-methyltransferase activity
HOO69_RS03895	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HOO69_RS03905	COG1482	cell wall glycoprotein biosynthetic process
HOO69_RS03910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HOO69_RS03910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HOO69_RS03910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HOO69_RS03915	COG2207	Transcriptional regulator
HOO69_RS03925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HOO69_RS03930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HOO69_RS03935	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HOO69_RS03950	COG5002	protein histidine kinase activity
HOO69_RS03950	COG3850	Histidine kinase
HOO69_RS03955	COG0745	RESPONSE REGULATOR receiver
HOO69_RS03960	COG0463	Glycosyl transferase, family 2
HOO69_RS03965	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HOO69_RS03980	COG1960	acyl-CoA dehydrogenase activity
HOO69_RS03995	COG0840	transmembrane signaling receptor activity
HOO69_RS04000	COG2850	peptidyl-arginine hydroxylation
HOO69_RS04010	COG3923	Primosomal replication protein n
HOO69_RS04015	COG0730	response to heat
HOO69_RS04020	COG1199	ATP-dependent helicase activity
HOO69_RS04030	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HOO69_RS04035	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HOO69_RS04055	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HOO69_RS04075	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
HOO69_RS04090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HOO69_RS04100	COG2268	Band 7 protein
HOO69_RS04110	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HOO69_RS04130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HOO69_RS04140	COG1757	Na H antiporter
HOO69_RS04150	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HOO69_RS04160	COG0131	Imidazoleglycerol-phosphate dehydratase
HOO69_RS04160	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HOO69_RS04165	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HOO69_RS04170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HOO69_RS04190	COG1227	inorganic diphosphatase activity
HOO69_RS04205	COG4172	Belongs to the ABC transporter superfamily
HOO69_RS04230	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HOO69_RS04235	COG1842	Phage shock protein A
HOO69_RS04265	COG0519	Catalyzes the synthesis of GMP from XMP
HOO69_RS04270	COG5380	lipid catabolic process
HOO69_RS04275	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HOO69_RS04280	COG0626	cystathionine gamma-synthase activity
HOO69_RS04290	COG0733	neurotransmitter:sodium symporter activity
HOO69_RS04300	COG0564	pseudouridine synthase activity
HOO69_RS04305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HOO69_RS04325	COG4964	Belongs to the GSP D family
HOO69_RS04380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOO69_RS04385	COG4136	ATPase activity
HOO69_RS04390	COG4135	transport system, permease component
HOO69_RS04395	COG4134	Bacterial extracellular solute-binding protein
HOO69_RS04405	COG3313	Fe-S protein
HOO69_RS04425	COG2200	EAL domain
HOO69_RS04435	COG2350	Protein conserved in bacteria
HOO69_RS04440	COG1607	acyl-coa hydrolase
HOO69_RS04480	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HOO69_RS04490	COG0417	DNA replication proofreading
HOO69_RS04495	COG2197	response regulator
HOO69_RS04500	COG0322	excinuclease ABC activity
HOO69_RS04530	COG3706	GGDEF domain
HOO69_RS04535	COG2133	pyrroloquinoline quinone binding
HOO69_RS04575	COG0456	acetyltransferase
HOO69_RS04585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOO69_RS04585	COG0072	phenylalanine-tRNA ligase activity
HOO69_RS04595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOO69_RS04610	COG2176	DNA-directed DNA polymerase activity
HOO69_RS04615	COG0517	IMP dehydrogenase activity
HOO69_RS04620	COG2186	Transcriptional regulator
HOO69_RS04625	COG2186	Transcriptional regulator
HOO69_RS04650	COG1917	Cupin 2, conserved barrel domain protein
HOO69_RS04655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HOO69_RS04660	COG0800	Aldolase
HOO69_RS04665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOO69_RS04670	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HOO69_RS04680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOO69_RS04680	COG0072	phenylalanine-tRNA ligase activity
HOO69_RS04685	COG1172	Belongs to the binding-protein-dependent transport system permease family
HOO69_RS04690	COG1172	Belongs to the binding-protein-dependent transport system permease family
HOO69_RS04695	COG1129	ABC transporter
HOO69_RS04705	COG2390	Transcriptional regulator
HOO69_RS04710	COG0667	Aldo Keto reductase
HOO69_RS04715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HOO69_RS04730	COG1454	alcohol dehydrogenase
HOO69_RS04745	COG1414	Transcriptional regulator
HOO69_RS04750	COG1414	Transcriptional regulator
HOO69_RS04755	COG3386	PFAM SMP-30 Gluconolaconase
HOO69_RS04770	COG1741	Belongs to the pirin family
HOO69_RS04780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HOO69_RS04780	COG1263	PTS System
HOO69_RS04785	COG1609	Transcriptional regulator
HOO69_RS04790	COG1621	beta-fructofuranosidase activity
HOO69_RS04795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HOO69_RS04815	COG0583	DNA-binding transcription factor activity
HOO69_RS04835	COG1335	isochorismatase
HOO69_RS04850	COG0346	lactoylglutathione lyase activity
HOO69_RS04855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOO69_RS04855	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOO69_RS04895	COG1605	Chorismate mutase
HOO69_RS04900	COG2824	Alkylphosphonate utilization operon protein PhnA
HOO69_RS04905	COG0789	Transcriptional regulator
HOO69_RS04910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HOO69_RS04920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HOO69_RS04925	COG1280	lysine exporter protein (LysE YggA)
HOO69_RS04995	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HOO69_RS05000	COG1280	lysine exporter protein (LysE YggA)
HOO69_RS05015	COG1115	amino acid carrier protein
HOO69_RS05045	COG2195	Cleaves the N-terminal amino acid of tripeptides
HOO69_RS05055	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HOO69_RS05065	COG0625	glutathione transferase activity
HOO69_RS05085	COG2885	chlorophyll binding
HOO69_RS05100	COG0247	lactate metabolic process
HOO69_RS05100	COG0277	FAD linked oxidase domain protein
HOO69_RS05115	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HOO69_RS05120	COG2986	histidine ammonia-lyase
HOO69_RS05125	COG0010	Belongs to the arginase family
HOO69_RS05130	COG1228	amidohydrolase
HOO69_RS05135	COG2188	Transcriptional regulator
HOO69_RS05140	COG4326	sporulation control protein
HOO69_RS05170	COG0295	cytidine deaminase activity
HOO69_RS05175	COG1346	cytolysis
HOO69_RS05180	COG1380	Effector of murein hydrolase LrgA
HOO69_RS05185	COG2925	Exonuclease
HOO69_RS05225	COG0702	epimerase
HOO69_RS05230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HOO69_RS05240	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HOO69_RS05265	COG4139	cobalamin transport
HOO69_RS05280	COG2203	Gaf domain
HOO69_RS05280	COG2199	diguanylate cyclase activity
HOO69_RS05295	COG0583	DNA-binding transcription factor activity
HOO69_RS05300	COG1119	ATPase activity
HOO69_RS05315	COG1451	nucleotide metabolic process
HOO69_RS05325	COG3063	Type IV pilus biogenesis stability protein PilW
HOO69_RS05330	COG2267	carboxylic ester hydrolase activity
HOO69_RS05365	COG2095	MarC family integral membrane protein
HOO69_RS05380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HOO69_RS05410	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HOO69_RS05515	COG3501	Rhs element vgr protein
HOO69_RS05535	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HOO69_RS05540	COG0372	Belongs to the citrate synthase family
HOO69_RS05550	COG2828	Protein conserved in bacteria
HOO69_RS05575	COG0561	phosphatase activity
HOO69_RS05580	COG0602	queuosine metabolic process
HOO69_RS05590	COG3706	GGDEF domain
HOO69_RS05620	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HOO69_RS05625	COG0840	transmembrane signaling receptor activity
HOO69_RS05630	COG1254	Belongs to the acylphosphatase family
HOO69_RS05635	COG2920	part of a sulfur-relay system
HOO69_RS05640	COG0670	Belongs to the BI1 family
HOO69_RS05645	COG1126	abc transporter atp-binding protein
HOO69_RS05650	COG0765	amino acid transport
HOO69_RS05655	COG4597	amino acid ABC transporter
HOO69_RS05660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HOO69_RS05670	COG1666	GTP binding
HOO69_RS05675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HOO69_RS05700	COG3008	intermembrane lipid transfer
HOO69_RS05705	COG2995	paraquat-inducible protein a
HOO69_RS05710	COG1132	(ABC) transporter
HOO69_RS05715	COG1956	GAF domain-containing protein
HOO69_RS05720	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
HOO69_RS05735	COG0308	aminopeptidase N
HOO69_RS05750	COG0167	dihydroorotate dehydrogenase activity
HOO69_RS05760	COG0116	Belongs to the methyltransferase superfamily
HOO69_RS05760	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HOO69_RS05770	COG0488	(ABC) transporter
HOO69_RS05785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HOO69_RS05790	COG1067	ATP-dependent peptidase activity
HOO69_RS05795	COG3120	sequence-specific DNA binding
HOO69_RS05820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HOO69_RS05825	COG2226	methyltransferase
HOO69_RS05930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HOO69_RS05980	COG3278	Belongs to the heme-copper respiratory oxidase family
HOO69_RS05995	COG2010	Cytochrome c
HOO69_RS06005	COG2217	Heavy metal translocating P-type atpase
HOO69_RS06020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HOO69_RS06025	COG0589	response to stress
HOO69_RS06030	COG0037	tRNA processing
HOO69_RS06035	COG0534	Mate efflux family protein
HOO69_RS06055	COG3842	ATPase activity
HOO69_RS06065	COG1177	transmembrane transport
HOO69_RS06070	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HOO69_RS06075	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HOO69_RS06080	COG2199	diguanylate cyclase activity
HOO69_RS06085	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HOO69_RS06090	COG0004	ammonium transporteR
HOO69_RS06105	COG0437	4 iron, 4 sulfur cluster binding
HOO69_RS06110	COG0243	molybdopterin cofactor binding
HOO69_RS06110	COG3383	formate dehydrogenase (NAD+) activity
HOO69_RS06140	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HOO69_RS06150	COG3040	lipid binding
HOO69_RS06185	COG2026	Addiction module toxin, RelE StbE family
HOO69_RS06210	COG2801	Transposase and inactivated derivatives
HOO69_RS06225	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HOO69_RS06225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HOO69_RS06245	COG1028	Short-chain dehydrogenase reductase Sdr
HOO69_RS06270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HOO69_RS06270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HOO69_RS06350	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOO69_RS06350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOO69_RS06405	COG0488	(ABC) transporter
HOO69_RS06415	COG4191	Histidine kinase
HOO69_RS06420	COG2204	response regulator
HOO69_RS06430	COG4662	Binding-protein-dependent transport system inner membrane component
HOO69_RS06435	COG3842	ATPase activity
HOO69_RS06440	COG0746	molybdenum cofactor guanylyltransferase activity
HOO69_RS06445	COG0303	'Molybdopterin
HOO69_RS06455	COG1940	carbohydrate kinase activity
HOO69_RS06470	COG0840	transmembrane signaling receptor activity
HOO69_RS06475	COG0791	NLP P60 protein
HOO69_RS06495	COG0307	riboflavin synthase, alpha
HOO69_RS06500	COG0534	Mate efflux family protein
HOO69_RS06515	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HOO69_RS06515	COG2885	chlorophyll binding
HOO69_RS06550	COG0438	transferase activity, transferring glycosyl groups
HOO69_RS06570	COG0110	maltose O-acetyltransferase activity
HOO69_RS06585	COG0438	transferase activity, transferring glycosyl groups
HOO69_RS06595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HOO69_RS06610	COG2205	protein histidine kinase activity
HOO69_RS06615	COG0745	RESPONSE REGULATOR receiver
HOO69_RS06635	COG3033	Beta-eliminating lyase
HOO69_RS06650	COG0745	RESPONSE REGULATOR receiver
HOO69_RS06655	COG0814	amino acid
HOO69_RS06660	COG1475	DNA binding
HOO69_RS06665	COG3969	phosphoadenosine phosphosulfate
HOO69_RS06710	COG2116	formate transmembrane transporter activity
HOO69_RS06720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HOO69_RS06725	COG0840	transmembrane signaling receptor activity
HOO69_RS06760	COG4565	transcriptional regulatory protein
HOO69_RS06765	COG3290	protein histidine kinase activity
HOO69_RS06775	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HOO69_RS06780	COG0848	biopolymer transport protein
HOO69_RS06785	COG0811	peptide transport
HOO69_RS06790	COG0811	peptide transport
HOO69_RS06810	COG0745	RESPONSE REGULATOR receiver
HOO69_RS06820	COG0039	L-malate dehydrogenase activity
HOO69_RS06830	COG0584	glycerophosphoryl diester phosphodiesterase
HOO69_RS06840	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HOO69_RS06860	COG0583	DNA-binding transcription factor activity
HOO69_RS06865	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HOO69_RS06870	COG1328	CTP reductase activity
HOO69_RS06875	COG0840	transmembrane signaling receptor activity
HOO69_RS06890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HOO69_RS06895	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOO69_RS06930	COG0019	diaminopimelate decarboxylase activity
HOO69_RS06975	COG4181	ATPase activity
HOO69_RS06980	COG0534	Mate efflux family protein
HOO69_RS06985	COG0702	epimerase
HOO69_RS06995	COG2814	Major facilitator Superfamily
HOO69_RS07005	COG1061	Type III restriction enzyme res subunit
HOO69_RS07020	COG0642	Histidine kinase
HOO69_RS07035	COG3710	Transcriptional regulator
HOO69_RS07040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HOO69_RS07045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HOO69_RS07065	COG4589	Belongs to the CDS family
HOO69_RS07090	COG3501	Rhs element vgr protein
HOO69_RS07100	COG0463	Glycosyl transferase, family 2
HOO69_RS07110	COG0109	protoheme IX farnesyltransferase activity
HOO69_RS07115	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HOO69_RS07120	COG1845	cytochrome c oxidase, subunit III
HOO69_RS07125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HOO69_RS07130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HOO69_RS07145	COG0583	DNA-binding transcription factor activity
HOO69_RS07150	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HOO69_RS07165	COG0523	cobalamin synthesis protein
HOO69_RS07180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOO69_RS07185	COG1780	Probably involved in ribonucleotide reductase function
HOO69_RS07195	COG0316	Belongs to the HesB IscA family
HOO69_RS07200	COG0719	Fe-S assembly protein
HOO69_RS07205	COG0396	ATPase activity
HOO69_RS07210	COG0719	Fe-S assembly protein
HOO69_RS07225	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
HOO69_RS07260	COG1858	cytochrome C peroxidase
HOO69_RS07290	COG3501	Rhs element vgr protein
HOO69_RS07300	COG2962	Rard protein
HOO69_RS07305	COG0531	amino acid
HOO69_RS07315	COG4667	esterase of the alpha-beta hydrolase superfamily
HOO69_RS07350	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HOO69_RS07365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HOO69_RS07370	COG3108	Peptidase M15
HOO69_RS07375	COG2989	Protein conserved in bacteria
HOO69_RS07400	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HOO69_RS07410	COG3706	GGDEF domain
HOO69_RS07425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HOO69_RS07440	COG3106	COG3106 Predicted ATPase
HOO69_RS07455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HOO69_RS07460	COG2205	protein histidine kinase activity
HOO69_RS07460	COG0784	Response regulator, receiver
HOO69_RS07470	COG0494	nUDIX hydrolase
HOO69_RS07475	COG0814	amino acid
HOO69_RS07480	COG1760	l-serine dehydratase
HOO69_RS07490	COG2356	endonuclease I
HOO69_RS07495	COG0814	amino acid
HOO69_RS07505	COG0659	secondary active sulfate transmembrane transporter activity
HOO69_RS07515	COG0840	transmembrane signaling receptor activity
HOO69_RS07520	COG0017	Asparaginyl-tRNA synthetase
HOO69_RS07535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HOO69_RS07545	COG2770	Histidine kinase
HOO69_RS07545	COG3437	response regulator, receiver
HOO69_RS07550	COG1448	Aminotransferase
HOO69_RS07570	COG1643	Atp-dependent helicase
HOO69_RS07575	COG0281	malic enzyme
HOO69_RS07585	COG2949	membrane
HOO69_RS07590	COG3706	GGDEF domain
HOO69_RS07600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HOO69_RS07610	COG0492	ferredoxin-NADP+ reductase activity
HOO69_RS07615	COG4988	ABC transporter
HOO69_RS07620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HOO69_RS07625	COG5001	Diguanylate cyclase
HOO69_RS07625	COG4251	negative regulation of phosphorylation
HOO69_RS07625	COG3706	GGDEF domain
HOO69_RS07625	COG2203	Gaf domain
HOO69_RS07640	COG1187	pseudouridine synthase activity
HOO69_RS07645	COG0009	L-threonylcarbamoyladenylate synthase
HOO69_RS07650	COG0613	PHP domain protein
HOO69_RS07660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HOO69_RS07665	COG0512	Glutamine amidotransferase of anthranilate synthase
HOO69_RS07670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HOO69_RS07675	COG0134	indole-3-glycerol-phosphate synthase activity
HOO69_RS07675	COG0135	phosphoribosylanthranilate isomerase activity
HOO69_RS07685	COG0159	tryptophan synthase activity
HOO69_RS07690	COG1301	dicarboxylic acid transport
HOO69_RS07710	COG1643	Atp-dependent helicase
HOO69_RS07740	COG3706	GGDEF domain
HOO69_RS07750	COG0443	Heat shock 70 kDa protein
HOO69_RS07755	COG0443	Heat shock 70 kDa protein
HOO69_RS07780	COG0457	Tetratricopeptide repeat
HOO69_RS07850	COG4790	Type iii secretion
HOO69_RS07855	COG4794	Type iii secretion
HOO69_RS07860	COG4791	protein targeting
HOO69_RS07865	COG4792	protein secretion
HOO69_RS07900	COG4669	(LipO)protein
HOO69_RS07935	COG1450	Type ii and iii secretion system protein
HOO69_RS08000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HOO69_RS08010	COG0673	inositol 2-dehydrogenase activity
HOO69_RS08020	COG0583	DNA-binding transcription factor activity
HOO69_RS08030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HOO69_RS08040	COG1764	response to oxidative stress
HOO69_RS08045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HOO69_RS08070	COG3300	MHYT domain
HOO69_RS08070	COG5001	Diguanylate cyclase
HOO69_RS08075	COG1032	radical SAM domain protein
HOO69_RS08080	COG3300	MHYT domain
HOO69_RS08080	COG5001	Diguanylate cyclase
HOO69_RS08085	COG2201	protein-glutamate methylesterase activity
HOO69_RS08090	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HOO69_RS08100	COG0835	chemotaxis
HOO69_RS08105	COG0840	transmembrane signaling receptor activity
HOO69_RS08110	COG2198	Histidine kinase
HOO69_RS08110	COG0643	Histidine kinase
HOO69_RS08120	COG0745	RESPONSE REGULATOR receiver
HOO69_RS08130	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HOO69_RS08140	COG4191	Histidine kinase
HOO69_RS08140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HOO69_RS08155	COG3070	regulator of competence-specific genes
HOO69_RS08165	COG2431	L-lysine efflux transmembrane transporter activity
HOO69_RS08175	COG0076	glutamate decarboxylase activity
HOO69_RS08180	COG1737	Transcriptional regulator
HOO69_RS08185	COG1012	belongs to the aldehyde dehydrogenase family
HOO69_RS08185	COG1454	alcohol dehydrogenase
HOO69_RS08190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HOO69_RS08200	COG4160	amino acid transport
HOO69_RS08225	COG1882	Formate acetyltransferase
HOO69_RS08240	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HOO69_RS08265	COG2766	serine protein kinase
HOO69_RS08270	COG2718	Belongs to the UPF0229 family
HOO69_RS08275	COG2719	SpoVR family
HOO69_RS08280	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HOO69_RS08295	COG1132	(ABC) transporter
HOO69_RS08300	COG0658	competence protein
HOO69_RS08300	COG2333	competence protein COMEC
HOO69_RS08325	COG4591	ABC-type transport system involved in lipoprotein release permease component
HOO69_RS08330	COG1136	(ABC) transporter
HOO69_RS08335	COG4591	ABC-type transport system involved in lipoprotein release permease component
HOO69_RS08345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HOO69_RS08355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HOO69_RS08360	COG1252	NADH dehydrogenase
HOO69_RS08365	COG3150	esterase
HOO69_RS08390	COG0537	adenosine 5'-monophosphoramidase activity
HOO69_RS08405	COG2186	Transcriptional regulator
HOO69_RS08410	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HOO69_RS08420	COG1674	ftsk spoiiie
HOO69_RS08425	COG1522	sequence-specific DNA binding
HOO69_RS08430	COG0686	Belongs to the AlaDH PNT family
HOO69_RS08435	COG3092	negative regulation of chromosome organization
HOO69_RS08440	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOO69_RS08445	COG0857	belongs to the CobB CobQ family
HOO69_RS08445	COG0280	phosphate acetyltransferase
HOO69_RS08450	COG3706	GGDEF domain
HOO69_RS08455	COG0435	Glutathione S-transferase
HOO69_RS08465	COG0444	Belongs to the ABC transporter superfamily
HOO69_RS08470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOO69_RS08475	COG0601	transmembrane transport
HOO69_RS08490	COG2067	long-chain fatty acid transport protein
HOO69_RS08505	COG1136	(ABC) transporter
HOO69_RS08505	COG0577	efflux transmembrane transporter activity
HOO69_RS08510	COG1136	(ABC) transporter
HOO69_RS08510	COG0577	efflux transmembrane transporter activity
HOO69_RS08515	COG0577	efflux transmembrane transporter activity
HOO69_RS08525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HOO69_RS08535	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HOO69_RS08575	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HOO69_RS08585	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HOO69_RS08610	COG2199	diguanylate cyclase activity
HOO69_RS08625	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HOO69_RS08630	COG1946	Acyl-CoA thioesterase
HOO69_RS08640	COG1522	sequence-specific DNA binding
HOO69_RS08645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HOO69_RS08665	COG0477	Major facilitator Superfamily
HOO69_RS08670	COG2855	membrane
HOO69_RS08685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HOO69_RS08685	COG2190	(PTS) system
HOO69_RS08685	COG1263	PTS System
HOO69_RS08705	COG0596	Alpha beta hydrolase
HOO69_RS08710	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HOO69_RS08715	COG1169	isochorismate synthase
HOO69_RS08720	COG0436	Aminotransferase
HOO69_RS08725	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HOO69_RS08745	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HOO69_RS08750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HOO69_RS08765	COG0513	Belongs to the DEAD box helicase family
HOO69_RS08800	COG0616	signal peptide processing
HOO69_RS08805	COG1028	Short-chain dehydrogenase reductase Sdr
HOO69_RS08825	COG0784	Response regulator, receiver
HOO69_RS08825	COG0835	chemotaxis
HOO69_RS08830	COG1940	carbohydrate kinase activity
HOO69_RS08835	COG0469	pyruvate kinase activity
HOO69_RS08840	COG4667	esterase of the alpha-beta hydrolase superfamily
HOO69_RS08860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HOO69_RS08860	COG1263	PTS System
HOO69_RS08865	COG0084	hydrolase, TatD family'
HOO69_RS08870	COG0470	DNA polymerase III
HOO69_RS08880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HOO69_RS08910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HOO69_RS08925	COG1399	metal-binding, possibly nucleic acid-binding protein
HOO69_RS08930	COG0424	maF-like protein
HOO69_RS08935	COG0564	pseudouridine synthase activity
HOO69_RS08940	COG1530	ribonuclease E activity
HOO69_RS08945	COG0659	secondary active sulfate transmembrane transporter activity
HOO69_RS08950	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HOO69_RS08955	COG0318	PFAM AMP-dependent synthetase and ligase
HOO69_RS08960	COG0596	Alpha beta hydrolase
HOO69_RS08965	COG3065	identical protein binding
HOO69_RS08975	COG1214	PFAM Peptidase M22, glycoprotease
HOO69_RS08980	COG1199	ATP-dependent helicase activity
HOO69_RS08990	COG0788	formyltetrahydrofolate deformylase activity
HOO69_RS08995	COG0446	pyridine nucleotide-disulphide oxidoreductase
HOO69_RS08995	COG1902	pentaerythritol trinitrate reductase activity
HOO69_RS09000	COG0616	signal peptide processing
HOO69_RS09015	COG0477	Major facilitator Superfamily
HOO69_RS09020	COG0252	asparaginase activity
HOO69_RS09030	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HOO69_RS09035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HOO69_RS09045	COG0653	protein targeting
HOO69_RS09055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOO69_RS09060	COG2203	Gaf domain
HOO69_RS09060	COG2199	diguanylate cyclase activity
HOO69_RS09070	COG4120	Belongs to the binding-protein-dependent transport system permease family
HOO69_RS09085	COG0583	DNA-binding transcription factor activity
HOO69_RS09110	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HOO69_RS09115	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HOO69_RS09125	COG0539	negative regulation of cytoplasmic translation
HOO69_RS09130	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HOO69_RS09135	COG1555	photosystem II stabilization
HOO69_RS09140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HOO69_RS09145	COG0776	regulation of translation
HOO69_RS09150	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HOO69_RS09165	COG0544	peptidyl-prolyl cis-trans isomerase activity
HOO69_RS09175	COG2204	response regulator
HOO69_RS09180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HOO69_RS09185	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HOO69_RS09190	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HOO69_RS09195	COG3842	ATPase activity
HOO69_RS09200	COG0395	ABC-type sugar transport system, permease component
HOO69_RS09205	COG1175	transmembrane transport
HOO69_RS09220	COG0745	RESPONSE REGULATOR receiver
HOO69_RS09230	COG0784	Response regulator, receiver
HOO69_RS09230	COG2205	protein histidine kinase activity
HOO69_RS09230	COG5002	protein histidine kinase activity
HOO69_RS09235	COG0840	transmembrane signaling receptor activity
HOO69_RS09260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HOO69_RS09270	COG2951	lytic endotransglycosylase activity
HOO69_RS09280	COG0850	regulation of cytokinetic process
HOO69_RS09285	COG2894	cell division
HOO69_RS09290	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HOO69_RS09300	COG1012	belongs to the aldehyde dehydrogenase family
HOO69_RS09300	COG1454	alcohol dehydrogenase
HOO69_RS09305	COG2095	MarC family integral membrane protein
HOO69_RS09310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HOO69_RS09320	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HOO69_RS09325	COG1757	Na H antiporter
HOO69_RS09365	COG0494	nUDIX hydrolase
HOO69_RS09370	COG0123	including yeast histone deacetylase and acetoin utilization protein
HOO69_RS09375	COG4580	involved in the transport of maltose and maltodextrins
HOO69_RS09380	COG1609	Transcriptional regulator
HOO69_RS09395	COG0395	ABC-type sugar transport system, permease component
HOO69_RS09400	COG2723	6-phospho-beta-galactosidase activity
HOO69_RS09405	COG3842	ATPase activity
HOO69_RS09410	COG1609	Transcriptional regulator
HOO69_RS09435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HOO69_RS09440	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HOO69_RS09460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HOO69_RS09470	COG0840	transmembrane signaling receptor activity
HOO69_RS09475	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HOO69_RS09490	COG0572	uridine kinase
HOO69_RS09495	COG0489	protein tyrosine kinase activity
HOO69_RS09530	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HOO69_RS09530	COG0617	tRNA 3'-terminal CCA addition
HOO69_RS09530	COG0517	IMP dehydrogenase activity
HOO69_RS09540	COG3706	GGDEF domain
HOO69_RS09545	COG0314	molybdopterin synthase activity
HOO69_RS09550	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HOO69_RS09555	COG0315	cyclic pyranopterin monophosphate synthase activity
HOO69_RS09560	COG0521	Mo-molybdopterin cofactor biosynthetic process
HOO69_RS09570	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HOO69_RS09575	COG2198	Histidine kinase
HOO69_RS09580	COG2204	response regulator
HOO69_RS09585	COG0556	nucleotide-excision repair
HOO69_RS09620	COG3842	ATPase activity
HOO69_RS09630	COG4657	Part of a membrane complex involved in electron transport
HOO69_RS09640	COG4656	Part of a membrane complex involved in electron transport
HOO69_RS09650	COG4659	FMN binding
HOO69_RS09655	COG4660	Part of a membrane complex involved in electron transport
HOO69_RS09660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HOO69_RS09665	COG0346	lactoylglutathione lyase activity
HOO69_RS09685	COG2056	Na+-H+ antiporter family
HOO69_RS09695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HOO69_RS09700	COG2716	regulation of RNA biosynthetic process
HOO69_RS09705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HOO69_RS09725	COG4783	chaperone-mediated protein folding
HOO69_RS09730	COG1393	Belongs to the ArsC family
HOO69_RS09750	COG2233	PERMEase
HOO69_RS09755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HOO69_RS09765	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HOO69_RS09770	COG2912	Transglutaminase-like superfamily
HOO69_RS09780	COG2890	protein-(glutamine-N5) methyltransferase activity
HOO69_RS09795	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HOO69_RS09805	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOO69_RS09930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HOO69_RS09940	COG1705	Flagellar rod assembly protein muramidase FlgJ
HOO69_RS09940	COG3951	Flagellar rod assembly protein muramidase FlgJ
HOO69_RS09950	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HOO69_RS09960	COG4787	bacterial-type flagellum-dependent cell motility
HOO69_RS09965	COG1749	Flagellar hook protein flgE
HOO69_RS09980	COG1815	bacterial-type flagellum-dependent cell motility
HOO69_RS09985	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HOO69_RS09990	COG0835	chemotaxis
HOO69_RS09990	COG0784	Response regulator, receiver
HOO69_RS10000	COG2747	anti-sigma28 factor FlgM
HOO69_RS10070	COG0582	viral genome integration into host DNA
HOO69_RS10085	COG2885	chlorophyll binding
HOO69_RS10105	COG2217	Heavy metal translocating P-type atpase
HOO69_RS10105	COG2608	mercury ion transmembrane transporter activity
HOO69_RS10130	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HOO69_RS10145	COG3710	Transcriptional regulator
HOO69_RS10165	COG0622	Phosphoesterase
HOO69_RS10190	COG1090	epimerase
HOO69_RS10195	COG0300	oxidoreductase activity
HOO69_RS10200	COG3118	belongs to the thioredoxin family
HOO69_RS10205	COG0330	HflC and HflK could
HOO69_RS10240	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
HOO69_RS10245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HOO69_RS10250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HOO69_RS10255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HOO69_RS10260	COG2190	(PTS) system
HOO69_RS10265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HOO69_RS10270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HOO69_RS10275	COG1702	phosphate starvation-inducible protein PhoH
HOO69_RS10280	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HOO69_RS10285	COG4535	Mg2 and Co2 transporter CorC
HOO69_RS10290	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HOO69_RS10295	COG2888	peptidyl-tyrosine sulfation
HOO69_RS10300	COG0495	leucyl-tRNA aminoacylation
HOO69_RS10305	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
HOO69_RS10310	COG1466	dna polymerase III delta subunit
HOO69_RS10315	COG0799	negative regulation of ribosome biogenesis
HOO69_RS10320	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HOO69_RS10330	COG0772	Belongs to the SEDS family
HOO69_RS10335	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HOO69_RS10340	COG1686	Belongs to the peptidase S11 family
HOO69_RS10345	COG2921	Belongs to the UPF0250 family
HOO69_RS10365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HOO69_RS10375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HOO69_RS10405	COG0366	Alpha amylase catalytic
HOO69_RS10410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HOO69_RS10410	COG1263	PTS System
HOO69_RS10425	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HOO69_RS10435	COG2011	ABC-type metal ion transport system permease component
HOO69_RS10440	COG1464	Belongs to the NlpA lipoprotein family
HOO69_RS10450	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HOO69_RS10465	COG1720	tRNA m6t6A37 methyltransferase activity
HOO69_RS10475	COG0121	glutamine amidotransferase
HOO69_RS10480	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HOO69_RS10485	COG1960	acyl-CoA dehydrogenase activity
HOO69_RS10500	COG0328	RNA-DNA hybrid ribonuclease activity
HOO69_RS10505	COG2226	methyltransferase
HOO69_RS10510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HOO69_RS10515	COG0741	lytic transglycosylase activity
HOO69_RS10515	COG1388	LysM domain
HOO69_RS10525	COG3021	interspecies interaction between organisms
HOO69_RS10530	COG0347	Belongs to the P(II) protein family
HOO69_RS10550	COG0587	DNA-directed DNA polymerase activity
HOO69_RS10575	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HOO69_RS10580	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HOO69_RS10585	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HOO69_RS10590	COG0750	zinc metalloprotease
HOO69_RS10595	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HOO69_RS10600	COG0575	Belongs to the CDS family
HOO69_RS10605	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HOO69_RS10610	COG0233	cytoplasmic translational termination
HOO69_RS10625	COG0052	Belongs to the universal ribosomal protein uS2 family
HOO69_RS10630	COG0024	Methionine aminopeptidase
HOO69_RS10645	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HOO69_RS10675	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HOO69_RS10675	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HOO69_RS10680	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HOO69_RS10685	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HOO69_RS10690	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HOO69_RS10710	COG2252	PERMEase
HOO69_RS10715	COG2195	Cleaves the N-terminal amino acid of tripeptides
HOO69_RS10720	COG0189	ligase activity
HOO69_RS10720	COG4067	protein conserved in archaea
HOO69_RS10725	COG0189	ligase activity
HOO69_RS10735	COG0733	neurotransmitter:sodium symporter activity
HOO69_RS10755	COG0514	ATP-dependent DNA helicase (RecQ)
HOO69_RS10760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOO69_RS10770	COG2991	Protein conserved in bacteria
HOO69_RS10775	COG1477	protein flavinylation
HOO69_RS10780	COG2871	sodium ion transport
HOO69_RS10785	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HOO69_RS10790	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HOO69_RS10800	COG1805	sodium ion transport
HOO69_RS10805	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HOO69_RS10810	COG0271	Belongs to the BolA IbaG family
HOO69_RS10830	COG2211	Major facilitator Superfamily
HOO69_RS10840	COG1595	DNA-templated transcription, initiation
HOO69_RS10855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HOO69_RS10860	COG0693	protein deglycase activity
HOO69_RS10870	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HOO69_RS10880	COG0560	Phosphoserine phosphatase
HOO69_RS10890	COG0813	purine-nucleoside phosphorylase activity
HOO69_RS10895	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HOO69_RS10900	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HOO69_RS10915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HOO69_RS10920	COG0084	hydrolase, TatD family'
HOO69_RS10930	COG3022	response to hydroperoxide
HOO69_RS10935	COG1115	amino acid carrier protein
HOO69_RS10950	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HOO69_RS10955	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HOO69_RS10960	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
HOO69_RS10970	COG0730	response to heat
HOO69_RS10975	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HOO69_RS10980	COG0505	Belongs to the CarA family
HOO69_RS10990	COG0494	nUDIX hydrolase
HOO69_RS11010	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HOO69_RS11015	COG0849	cell division
HOO69_RS11020	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HOO69_RS11030	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HOO69_RS11035	COG0772	Belongs to the SEDS family
HOO69_RS11040	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HOO69_RS11050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HOO69_RS11060	COG0768	penicillin binding
HOO69_RS11065	COG3116	cell division
HOO69_RS11080	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HOO69_RS11085	COG3107	peptidoglycan biosynthetic process
HOO69_RS11095	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HOO69_RS11105	COG2969	positive regulation of protein catabolic process
HOO69_RS11110	COG0625	glutathione transferase activity
HOO69_RS11115	COG2857	Cytochrome c1
HOO69_RS11120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HOO69_RS11125	COG0723	plastoquinol--plastocyanin reductase activity
HOO69_RS11140	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HOO69_RS11145	COG3105	Protein conserved in bacteria
HOO69_RS11150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HOO69_RS11155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HOO69_RS11170	COG3150	esterase
HOO69_RS11180	COG3151	Protein conserved in bacteria
HOO69_RS11185	COG0494	nUDIX hydrolase
HOO69_RS11190	COG1538	Outer membrane efflux protein
HOO69_RS11200	COG5002	protein histidine kinase activity
HOO69_RS11200	COG0784	Response regulator, receiver
HOO69_RS11200	COG2198	Histidine kinase
HOO69_RS11205	COG4251	negative regulation of phosphorylation
HOO69_RS11205	COG3706	GGDEF domain
HOO69_RS11205	COG2203	Gaf domain
HOO69_RS11205	COG5001	Diguanylate cyclase
HOO69_RS11210	COG1242	4 iron, 4 sulfur cluster binding
HOO69_RS11215	COG0067	glutamate synthase
HOO69_RS11215	COG0069	glutamate synthase activity
HOO69_RS11215	COG0070	glutamate synthase
HOO69_RS11225	COG0070	glutamate synthase
HOO69_RS11225	COG0069	glutamate synthase activity
HOO69_RS11225	COG0067	glutamate synthase
HOO69_RS11230	COG0493	'glutamate synthase
HOO69_RS11255	COG0195	Participates in both transcription termination and antitermination
HOO69_RS11260	COG0779	Required for maturation of 30S ribosomal subunits
HOO69_RS11275	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HOO69_RS11280	COG3153	acetyltransferase
HOO69_RS11285	COG3154	lipid carrier protein
HOO69_RS11295	COG0826	peptidase U32
HOO69_RS11300	COG0826	peptidase U32
HOO69_RS11330	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HOO69_RS11340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HOO69_RS11345	COG2860	membrane
HOO69_RS11350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HOO69_RS11370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HOO69_RS11380	COG0745	RESPONSE REGULATOR receiver
HOO69_RS11390	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HOO69_RS11400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HOO69_RS11405	COG3025	triphosphatase activity
HOO69_RS11410	COG1392	Phosphate transport regulator
HOO69_RS11420	COG4991	sh3 domain protein
HOO69_RS11440	COG0148	phosphopyruvate hydratase activity
HOO69_RS11450	COG3956	TIGRFAM MazG family protein
HOO69_RS11455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HOO69_RS11465	COG3850	Histidine kinase
HOO69_RS11465	COG4999	Histidine kinase
HOO69_RS11465	COG2205	protein histidine kinase activity
HOO69_RS11465	COG3437	response regulator, receiver
HOO69_RS11485	COG0736	holo-[acyl-carrier-protein] synthase activity
HOO69_RS11490	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HOO69_RS11495	COG1381	Involved in DNA repair and RecF pathway recombination
HOO69_RS11500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HOO69_RS11520	COG3086	response to oxidative stress
HOO69_RS11525	COG3026	antisigma factor binding
HOO69_RS11535	COG1595	DNA-templated transcription, initiation
HOO69_RS11540	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HOO69_RS11550	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HOO69_RS11570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HOO69_RS11575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HOO69_RS11585	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HOO69_RS11595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HOO69_RS11600	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HOO69_RS11605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HOO69_RS11615	COG0028	Belongs to the TPP enzyme family
HOO69_RS11620	COG1022	Amp-dependent synthetase and ligase
HOO69_RS11625	COG0583	DNA-binding transcription factor activity
HOO69_RS11640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HOO69_RS11645	COG0473	3-isopropylmalate dehydrogenase activity
HOO69_RS11710	COG3437	response regulator, receiver
HOO69_RS11730	COG1854	S-ribosylhomocysteine lyase activity
HOO69_RS11740	COG2918	glutathione biosynthetic process
HOO69_RS11745	COG0612	Peptidase, M16
HOO69_RS11750	COG1238	metal cluster binding
HOO69_RS11760	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HOO69_RS11765	COG0511	ligase activity, forming carbon-carbon bonds
HOO69_RS11765	COG5016	pyruvate
HOO69_RS11770	COG3630	sodium ion export across plasma membrane
HOO69_RS11820	COG0527	aspartate kinase activity
HOO69_RS11835	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HOO69_RS11840	COG1546	Belongs to the CinA family
HOO69_RS11845	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HOO69_RS11850	COG0795	lipopolysaccharide-transporting ATPase activity
HOO69_RS11855	COG0795	lipopolysaccharide-transporting ATPase activity
HOO69_RS11865	COG2927	DNA polymerase III (CHI subunit)
HOO69_RS11870	COG0525	valine-tRNA ligase activity
HOO69_RS11880	COG4269	membrane
HOO69_RS11890	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOO69_RS11895	COG0564	pseudouridine synthase activity
HOO69_RS11900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HOO69_RS11905	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HOO69_RS11920	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
HOO69_RS11925	COG0251	oxidation-reduction process
HOO69_RS11935	COG0039	L-malate dehydrogenase activity
HOO69_RS11940	COG1438	arginine binding
HOO69_RS11945	COG2358	TRAP transporter, solute receptor (TAXI family
HOO69_RS11955	COG0589	response to stress
HOO69_RS11975	COG2235	arginine
HOO69_RS11980	COG0312	modulator of DNA gyrase
HOO69_RS11985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HOO69_RS11990	COG3164	Protein of unknown function
HOO69_RS11995	COG1530	ribonuclease E activity
HOO69_RS12000	COG0424	maF-like protein
HOO69_RS12005	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HOO69_RS12010	COG1792	Involved in formation and maintenance of cell shape
HOO69_RS12015	COG1077	Cell shape determining protein MreB Mrl
HOO69_RS12045	COG4969	Belongs to the N-Me-Phe pilin family
HOO69_RS12060	COG1459	type II secretion system
HOO69_RS12065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HOO69_RS12100	COG2199	diguanylate cyclase activity
HOO69_RS12100	COG2200	EAL domain
HOO69_RS12105	COG0629	single-stranded DNA binding
HOO69_RS12110	COG2197	response regulator
HOO69_RS12120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HOO69_RS12130	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HOO69_RS12135	COG0527	aspartate kinase activity
HOO69_RS12145	COG3028	Belongs to the UPF0307 family
HOO69_RS12150	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HOO69_RS12155	COG1178	ABC-type Fe3 transport system permease component
HOO69_RS12160	COG4143	(ABC) transporter
HOO69_RS12165	COG0163	prenyltransferase activity
HOO69_RS12170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HOO69_RS12185	COG2105	PFAM AIG2 family protein
HOO69_RS12190	COG2911	Protein conserved in bacteria
HOO69_RS12195	COG0729	surface antigen
HOO69_RS12200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOO69_RS12205	COG4566	intracellular signal transduction
HOO69_RS12205	COG0745	RESPONSE REGULATOR receiver
HOO69_RS12210	COG0004	ammonium transporteR
HOO69_RS12220	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HOO69_RS12235	COG1136	(ABC) transporter
HOO69_RS12260	COG0432	Pfam Uncharacterised protein family UPF0047
HOO69_RS12275	COG0251	oxidation-reduction process
HOO69_RS12285	COG2964	Protein conserved in bacteria
HOO69_RS12295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HOO69_RS12320	COG2965	DNA replication, synthesis of RNA primer
HOO69_RS12325	COG0360	Binds together with S18 to 16S ribosomal RNA
HOO69_RS12330	COG2194	sulfuric ester hydrolase activity
HOO69_RS12335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HOO69_RS12345	COG2906	2 iron, 2 sulfur cluster binding
HOO69_RS12355	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HOO69_RS12370	COG2168	tRNA wobble position uridine thiolation
HOO69_RS12375	COG2923	Belongs to the DsrF TusC family
HOO69_RS12380	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HOO69_RS12385	COG2964	Protein conserved in bacteria
HOO69_RS12390	COG0545	Peptidyl-prolyl cis-trans isomerase
HOO69_RS12400	COG2900	Belongs to the SlyX family
HOO69_RS12410	COG0330	HflC and HflK could
HOO69_RS12415	COG0330	HflC and HflK could
HOO69_RS12420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HOO69_RS12435	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HOO69_RS12445	COG0802	atpase or kinase
HOO69_RS12450	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HOO69_RS12510	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HOO69_RS12515	COG1162	GTPase activity
HOO69_RS12525	COG0471	metal ion transport
HOO69_RS12525	COG0490	domain, Protein
HOO69_RS12530	COG0840	transmembrane signaling receptor activity
HOO69_RS12545	COG4942	peptidase
HOO69_RS12570	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
HOO69_RS12580	COG0085	RNA polymerase activity
HOO69_RS12590	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HOO69_RS12605	COG0250	Participates in transcription elongation, termination and antitermination
HOO69_RS12610	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HOO69_RS12640	COG1072	(Pantothenic acid kinase))
HOO69_RS12655	COG0149	triose-phosphate isomerase activity
HOO69_RS12660	COG0534	Mate efflux family protein
HOO69_RS12665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HOO69_RS12670	COG1575	Belongs to the MenA family. Type 1 subfamily
HOO69_RS12675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HOO69_RS12680	COG1509	lysine 2,3-aminomutase activity
HOO69_RS12690	COG1285	pathogenesis
HOO69_RS12695	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HOO69_RS12705	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HOO69_RS12710	COG3678	ATP-independent chaperone mediated protein folding
HOO69_RS12715	COG0745	RESPONSE REGULATOR receiver
HOO69_RS12720	COG2205	protein histidine kinase activity
HOO69_RS12725	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HOO69_RS12730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HOO69_RS12735	COG0180	Tryptophanyl-tRNA synthetase
HOO69_RS12740	COG0546	phosphoglycolate phosphatase activity
HOO69_RS12745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HOO69_RS12750	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HOO69_RS12795	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HOO69_RS12805	COG0678	peroxiredoxin activity
HOO69_RS12805	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HOO69_RS12810	COG0251	oxidation-reduction process
HOO69_RS12820	COG0165	Argininosuccinate lyase
HOO69_RS12820	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HOO69_RS12825	COG0137	argininosuccinate synthase activity
HOO69_RS12830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HOO69_RS12835	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HOO69_RS12845	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HOO69_RS12850	COG1695	Transcriptional regulator
HOO69_RS12855	COG1045	serine acetyltransferase
HOO69_RS12870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HOO69_RS12875	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HOO69_RS12880	COG1053	succinate dehydrogenase
HOO69_RS12885	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HOO69_RS12900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HOO69_RS12915	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HOO69_RS12920	COG1609	Transcriptional regulator
HOO69_RS12925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HOO69_RS12935	COG0281	malic enzyme
HOO69_RS12945	COG0626	cystathionine gamma-synthase activity
HOO69_RS12950	COG0460	homoserine dehydrogenase
HOO69_RS12950	COG0527	aspartate kinase activity
HOO69_RS12965	COG1494	fructose-1,6-bisphosphatase
HOO69_RS13035	COG4206	TonB-dependent receptor
HOO69_RS13055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HOO69_RS13065	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HOO69_RS13070	COG0534	Mate efflux family protein
HOO69_RS13085	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HOO69_RS13090	COG2937	Belongs to the GPAT DAPAT family
HOO69_RS13095	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HOO69_RS13100	COG3161	chorismate lyase activity
HOO69_RS13105	COG1580	Controls the rotational direction of flagella during chemotaxis
HOO69_RS13110	COG0705	Rhomboid family
HOO69_RS13115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HOO69_RS13125	COG2177	Part of the ABC transporter FtsEX involved in
HOO69_RS13130	COG2884	Cell division ATP-binding protein ftsE
HOO69_RS13135	COG0552	protein localization to endoplasmic reticulum
HOO69_RS13140	COG0742	ribosomal rna small subunit methyltransferase
HOO69_RS13150	COG2095	MarC family integral membrane protein
HOO69_RS13190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HOO69_RS13195	COG0640	Transcriptional regulator
HOO69_RS13200	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HOO69_RS13205	COG1280	lysine exporter protein (LysE YggA)
HOO69_RS13210	COG2267	carboxylic ester hydrolase activity
HOO69_RS13215	COG0561	phosphatase activity
HOO69_RS13235	COG2199	diguanylate cyclase activity
HOO69_RS13235	COG3287	FIST C domain
HOO69_RS13235	COG2200	EAL domain
HOO69_RS13240	COG1011	Hydrolase
HOO69_RS13245	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HOO69_RS13255	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HOO69_RS13260	COG0019	diaminopimelate decarboxylase activity
HOO69_RS13270	COG1965	Belongs to the frataxin family
HOO69_RS13275	COG3072	Adenylate cyclase
HOO69_RS13285	COG1587	Uroporphyrinogen-III synthase
HOO69_RS13290	COG2959	enzyme of heme biosynthesis
HOO69_RS13295	COG3071	HemY protein
HOO69_RS13345	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HOO69_RS13360	COG3118	belongs to the thioredoxin family
HOO69_RS13370	COG0248	Ppx GppA phosphatase
HOO69_RS13375	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HOO69_RS13385	COG0514	ATP-dependent DNA helicase (RecQ)
HOO69_RS13390	COG2962	Rard protein
HOO69_RS13400	COG1280	lysine exporter protein (LysE YggA)
HOO69_RS13405	COG0405	Gamma-glutamyltransferase
HOO69_RS13415	COG0210	DNA helicase
HOO69_RS13425	COG3220	belongs to the UPF0276 family
HOO69_RS13450	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HOO69_RS13460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HOO69_RS13480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOO69_RS13490	COG0747	negative chemotaxis
HOO69_RS13535	COG1309	transcriptional regulator
HOO69_RS13540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HOO69_RS13545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HOO69_RS13550	COG2960	long-chain fatty acid transporting porin activity
HOO69_RS13555	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HOO69_RS13560	COG0583	DNA-binding transcription factor activity
HOO69_RS13565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HOO69_RS13590	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HOO69_RS13595	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOO69_RS13595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOO69_RS13610	COG0084	hydrolase, TatD family'
HOO69_RS13615	COG0805	protein transport
HOO69_RS13620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HOO69_RS13640	COG2226	methyltransferase
HOO69_RS13645	COG1322	Protein conserved in bacteria
HOO69_RS13655	COG1639	'signal transduction protein
HOO69_RS13670	COG2081	HI0933 family
HOO69_RS13680	COG1528	Iron-storage protein
HOO69_RS13685	COG0589	response to stress
HOO69_RS13700	COG0742	ribosomal rna small subunit methyltransferase
HOO69_RS13705	COG5001	Diguanylate cyclase
HOO69_RS13705	COG5002	protein histidine kinase activity
HOO69_RS13710	COG1522	sequence-specific DNA binding
HOO69_RS13730	COG0006	proline dipeptidase activity
HOO69_RS13730	COG0006	proline dipeptidase activity
HOO69_RS13745	COG2104	thiamine diphosphate biosynthetic process
HOO69_RS13750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HOO69_RS13765	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOO69_RS13770	COG2132	Multicopper oxidase
HOO69_RS13825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HOO69_RS13830	COG1739	Uncharacterized protein family UPF0029
HOO69_RS13840	COG0183	Belongs to the thiolase family
HOO69_RS13845	COG0583	DNA-binding transcription factor activity
HOO69_RS13850	COG2814	Major facilitator Superfamily
HOO69_RS13860	COG0765	amino acid transport
HOO69_RS13870	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HOO69_RS13875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HOO69_RS13880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HOO69_RS13890	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOO69_RS13895	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HOO69_RS13910	COG3312	ion transport
HOO69_RS13915	COG1475	DNA binding
HOO69_RS13920	COG1192	Involved in chromosome partitioning
HOO69_RS13930	COG0445	tRNA wobble uridine modification
HOO69_RS13935	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HOO69_RS13940	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HOO69_RS13945	COG0706	membrane insertase activity
HOO69_RS13955	COG0594	ribonuclease P activity
HOO69_RS13965	COG1126	abc transporter atp-binding protein
HOO69_RS13985	COG0592	DNA-directed DNA polymerase activity
HOO69_RS13990	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HOO69_RS13995	COG0187	DNA topoisomerase II activity
HOO69_RS14000	COG0071	Belongs to the small heat shock protein (HSP20) family
HOO69_RS14010	COG3977	Valine--pyruvate aminotransferase
HOO69_RS14015	COG0751	glycine-tRNA ligase activity
HOO69_RS14025	COG2119	membrane
HOO69_RS14035	COG0425	Belongs to the sulfur carrier protein TusA family
HOO69_RS14050	COG0604	alcohol dehydrogenase
HOO69_RS14060	COG0129	dihydroxy-acid dehydratase activity
HOO69_RS14065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HOO69_RS14070	COG3978	acetolactate synthase activity
HOO69_RS14090	COG0758	DNA mediated transformation
HOO69_RS14135	COG0204	Acyl-transferase
HOO69_RS14140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HOO69_RS14145	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HOO69_RS14155	COG3084	Protein conserved in bacteria
HOO69_RS14165	COG4326	sporulation control protein
HOO69_RS14170	COG1272	protein, Hemolysin III
HOO69_RS14175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HOO69_RS14180	COG0569	domain protein
HOO69_RS14185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HOO69_RS14185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HOO69_RS14190	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HOO69_RS14195	COG0242	peptide deformylase activity
HOO69_RS14200	COG1652	LysM domain
HOO69_RS14205	COG0758	DNA mediated transformation
HOO69_RS14210	COG2922	Belongs to the Smg family
HOO69_RS14215	COG0551	DNA topoisomerase type I activity
HOO69_RS14220	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HOO69_RS14225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HOO69_RS14230	COG0009	L-threonylcarbamoyladenylate synthase
HOO69_RS14235	COG0408	coproporphyrinogen oxidase activity
HOO69_RS14240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HOO69_RS14250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HOO69_RS14295	COG5001	Diguanylate cyclase
HOO69_RS14295	COG3300	MHYT domain
HOO69_RS14305	COG3852	Histidine kinase
HOO69_RS14315	COG0174	glutamine synthetase
HOO69_RS14345	COG1490	D-aminoacyl-tRNA deacylase activity
HOO69_RS14350	COG0456	acetyltransferase
HOO69_RS14360	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HOO69_RS14365	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HOO69_RS14370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HOO69_RS14375	COG3031	protein transport across the cell outer membrane
HOO69_RS14385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HOO69_RS14390	COG1459	type II secretion system
HOO69_RS14395	COG2165	general secretion pathway protein
HOO69_RS14400	COG2165	general secretion pathway protein
HOO69_RS14405	COG2165	general secretion pathway protein
HOO69_RS14410	COG4795	General secretion pathway protein
HOO69_RS14415	COG3156	type II secretion system protein K
HOO69_RS14420	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HOO69_RS14425	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HOO69_RS14435	COG2205	protein histidine kinase activity
HOO69_RS14440	COG0745	RESPONSE REGULATOR receiver
HOO69_RS14445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HOO69_RS14455	COG2183	response to ionizing radiation
HOO69_RS14480	COG0494	nUDIX hydrolase
HOO69_RS14485	COG1218	3'(2'),5'-bisphosphate nucleotidase
HOO69_RS14490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HOO69_RS14495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOO69_RS14500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HOO69_RS14505	COG1758	RNA polymerase activity
HOO69_RS14510	COG0194	GDP metabolic process
HOO69_RS14515	COG2252	PERMEase
HOO69_RS14530	COG1561	YicC-like family, N-terminal region
HOO69_RS14535	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HOO69_RS14545	COG1560	Kdo2-lipid A biosynthetic process
HOO69_RS14550	COG1560	Kdo2-lipid A biosynthetic process
HOO69_RS14555	COG1309	transcriptional regulator
HOO69_RS14560	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HOO69_RS14565	COG2003	Belongs to the UPF0758 family
HOO69_RS14590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HOO69_RS14595	COG0859	PFAM glycosyl transferase family 9
HOO69_RS14600	COG0463	Glycosyl transferase, family 2
HOO69_RS14605	COG0859	PFAM glycosyl transferase family 9
HOO69_RS14610	COG3642	lipopolysaccharide core region biosynthetic process
HOO69_RS14640	COG1088	dTDP-glucose 4,6-dehydratase activity
HOO69_RS14645	COG1519	Transferase
HOO69_RS14655	COG0859	PFAM glycosyl transferase family 9
HOO69_RS14670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HOO69_RS14675	COG0673	inositol 2-dehydrogenase activity
HOO69_RS14680	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HOO69_RS14700	COG1086	Polysaccharide biosynthesis protein
HOO69_RS14705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HOO69_RS14710	COG1083	cytidylyl-transferase
HOO69_RS14720	COG2089	acid synthase
HOO69_RS14730	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HOO69_RS14790	COG0438	transferase activity, transferring glycosyl groups
HOO69_RS14800	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HOO69_RS14810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOO69_RS14815	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HOO69_RS14815	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HOO69_RS14820	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HOO69_RS14850	COG0459	protein refolding
HOO69_RS14855	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HOO69_RS14860	COG1573	uracil-dna glycosylase
HOO69_RS14875	COG1253	flavin adenine dinucleotide binding
HOO69_RS14890	COG0151	Belongs to the GarS family
HOO69_RS14900	COG0789	Transcriptional regulator
HOO69_RS14905	COG3706	GGDEF domain
HOO69_RS14910	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HOO69_RS14915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOO69_RS14925	COG0439	Biotin carboxylase
HOO69_RS14930	COG0511	ligase activity, forming carbon-carbon bonds
HOO69_RS14935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HOO69_RS14940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HOO69_RS14955	COG2814	Major facilitator Superfamily
HOO69_RS14960	COG2205	protein histidine kinase activity
HOO69_RS14960	COG0784	Response regulator, receiver
HOO69_RS14970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOO69_RS14980	COG2095	MarC family integral membrane protein
HOO69_RS14990	COG4232	protein-disulfide reductase activity
HOO69_RS14995	COG1438	arginine binding
HOO69_RS15000	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
HOO69_RS15005	COG0540	Belongs to the ATCase OTCase family
HOO69_RS15010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HOO69_RS15025	COG1288	antiporter activity
HOO69_RS15030	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HOO69_RS15035	COG1027	Aspartate ammonia-lyase
HOO69_RS15055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HOO69_RS15075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HOO69_RS15080	COG3954	Phosphoribulokinase
HOO69_RS15085	COG3089	Belongs to the UPF0270 family
HOO69_RS15090	COG0429	hydrolase of the alpha beta-hydrolase fold
HOO69_RS15100	COG0488	(ABC) transporter
HOO69_RS15105	COG2249	NAD(P)H dehydrogenase (quinone) activity
HOO69_RS15115	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HOO69_RS15120	COG1047	Peptidyl-prolyl cis-trans
HOO69_RS15125	COG1446	asparaginase
HOO69_RS15130	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HOO69_RS15135	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HOO69_RS15140	COG0402	S-adenosylhomocysteine deaminase activity
HOO69_RS15145	COG0557	exoribonuclease II activity
HOO69_RS15150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOO69_RS15160	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HOO69_RS15165	COG0088	Forms part of the polypeptide exit tunnel
HOO69_RS15180	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HOO69_RS15185	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HOO69_RS15190	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HOO69_RS15205	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HOO69_RS15220	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HOO69_RS15235	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HOO69_RS15250	COG1841	ribosomal large subunit assembly
HOO69_RS15260	COG0201	protein transport
HOO69_RS15265	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HOO69_RS15270	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HOO69_RS15275	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HOO69_RS15290	COG0203	ribosomal protein L17
HOO69_RS15300	COG0545	Peptidyl-prolyl cis-trans isomerase
HOO69_RS15315	COG2153	protein acetylation
HOO69_RS15325	COG0737	Belongs to the 5'-nucleotidase family
HOO69_RS15330	COG1648	precorrin-2 dehydrogenase activity
HOO69_RS15330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HOO69_RS15335	COG0175	sulfate reduction
HOO69_RS15345	COG3273	potassium ion transport
HOO69_RS15345	COG0471	metal ion transport
HOO69_RS15350	COG0529	Catalyzes the synthesis of activated sulfate
HOO69_RS15360	COG0735	belongs to the Fur family
HOO69_RS15365	COG2205	protein histidine kinase activity
HOO69_RS15365	COG5002	protein histidine kinase activity
HOO69_RS15365	COG0784	Response regulator, receiver
HOO69_RS15370	COG3437	response regulator, receiver
HOO69_RS15395	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HOO69_RS15400	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HOO69_RS15435	COG2801	Transposase and inactivated derivatives
HOO69_RS15460	COG4946	Tricorn protease homolog
HOO69_RS15460	COG0793	Belongs to the peptidase S41A family
HOO69_RS15535	COG0673	inositol 2-dehydrogenase activity
HOO69_RS15550	COG0251	oxidation-reduction process
HOO69_RS15560	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HOO69_RS15585	COG0148	phosphopyruvate hydratase activity
HOO69_RS15645	COG2274	protein secretion by the type I secretion system
HOO69_RS15655	COG0583	DNA-binding transcription factor activity
HOO69_RS15660	COG1309	transcriptional regulator
HOO69_RS15680	COG0840	transmembrane signaling receptor activity
HOO69_RS15695	COG1132	(ABC) transporter
HOO69_RS15700	COG1132	(ABC) transporter
HOO69_RS15735	COG0745	RESPONSE REGULATOR receiver
HOO69_RS15740	COG2205	protein histidine kinase activity
HOO69_RS15745	COG4452	Inner membrane protein CreD
HOO69_RS15760	COG0583	DNA-binding transcription factor activity
HOO69_RS15775	COG3710	Transcriptional regulator
HOO69_RS15820	COG1917	Cupin 2, conserved barrel domain protein
HOO69_RS15820	COG4977	sequence-specific DNA binding
HOO69_RS15835	COG2003	Belongs to the UPF0758 family
HOO69_RS15995	COG1714	RDD family
HOO69_RS16010	COG1012	belongs to the aldehyde dehydrogenase family
HOO69_RS16030	COG1309	transcriptional regulator
HOO69_RS16045	COG0753	catalase activity
HOO69_RS16055	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HOO69_RS16065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HOO69_RS16135	COG1192	Involved in chromosome partitioning
HOO69_RS16145	COG2814	Major facilitator Superfamily
HOO69_RS16170	COG1028	Short-chain dehydrogenase reductase Sdr
HOO69_RS16180	COG1902	pentaerythritol trinitrate reductase activity
HOO69_RS16185	COG1881	PFAM PEBP family protein
HOO69_RS16205	COG0814	amino acid
HOO69_RS16290	COG1716	ATPase activity
HOO69_RS16325	COG3501	Rhs element vgr protein
HOO69_RS16360	COG3710	Transcriptional regulator
HOO69_RS16380	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HOO69_RS16385	COG1012	belongs to the aldehyde dehydrogenase family
HOO69_RS16400	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HOO69_RS16480	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HOO69_RS16490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HOO69_RS16515	COG0529	Catalyzes the synthesis of activated sulfate
HOO69_RS16520	COG0490	domain, Protein
HOO69_RS16520	COG0471	metal ion transport
HOO69_RS16525	COG2895	sulfate adenylyltransferase (ATP) activity
HOO69_RS16530	COG0175	sulfate reduction
HOO69_RS16575	COG0346	lactoylglutathione lyase activity
HOO69_RS16585	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HOO69_RS16610	COG0768	penicillin binding
HOO69_RS16630	COG2026	Addiction module toxin, RelE StbE family
HOO69_RS16755	COG3706	GGDEF domain
HOO69_RS16795	COG3842	ATPase activity
HOO69_RS16800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HOO69_RS16820	COG1175	transmembrane transport
HOO69_RS16825	COG0583	DNA-binding transcription factor activity
HOO69_RS16840	COG2814	Major facilitator Superfamily
HOO69_RS16845	COG3214	Protein conserved in bacteria
HOO69_RS16850	COG1028	Short-chain dehydrogenase reductase Sdr
HOO69_RS16850	COG3321	synthase
HOO69_RS16850	COG0604	alcohol dehydrogenase
HOO69_RS16860	COG0646	methionine synthase
HOO69_RS16860	COG1410	methionine synthase
HOO69_RS16865	COG2176	DNA-directed DNA polymerase activity
HOO69_RS16905	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HOO69_RS16910	COG0840	transmembrane signaling receptor activity
HOO69_RS16915	COG0835	chemotaxis
HOO69_RS16930	COG0745	RESPONSE REGULATOR receiver
HOO69_RS16940	COG1444	tRNA N-acetyltransferase activity
HOO69_RS16970	COG4608	Belongs to the ABC transporter superfamily
HOO69_RS16975	COG0444	Belongs to the ABC transporter superfamily
HOO69_RS17010	COG1028	Short-chain dehydrogenase reductase Sdr
HOO69_RS17020	COG1733	regulation of RNA biosynthetic process
HOO69_RS17045	COG0110	maltose O-acetyltransferase activity
HOO69_RS17050	COG1278	Cold shock
HOO69_RS17060	COG1342	Belongs to the UPF0251 family
HOO69_RS17075	COG0583	DNA-binding transcription factor activity
HOO69_RS17095	COG0697	spore germination
HOO69_RS17125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HOO69_RS17130	COG2135	peptidase activity
HOO69_RS17140	COG1846	Transcriptional regulator
HOO69_RS17150	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HOO69_RS17155	COG3960	tartronate-semialdehyde synthase activity
HOO69_RS17165	COG2084	Dehydrogenase
HOO69_RS17170	COG3835	regulator
HOO69_RS17175	COG2610	gluconate transmembrane transporter activity
HOO69_RS17180	COG1929	Belongs to the glycerate kinase type-1 family
HOO69_RS17185	COG1901	pseudouridine methyltransferase
HOO69_RS17225	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HOO69_RS17245	COG0589	response to stress
HOO69_RS17280	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HOO69_RS17280	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HOO69_RS17285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HOO69_RS17300	COG0768	penicillin binding
HOO69_RS17320	COG0583	DNA-binding transcription factor activity
HOO69_RS17330	COG0351	phosphomethylpyrimidine kinase
HOO69_RS17335	COG1116	anion transmembrane transporter activity
HOO69_RS17340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HOO69_RS17345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HOO69_RS17350	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HOO69_RS17355	COG2203	Gaf domain
HOO69_RS17355	COG2199	diguanylate cyclase activity
HOO69_RS17360	COG0671	phosphoesterase, PA-phosphatase related
HOO69_RS17385	COG0583	DNA-binding transcription factor activity
HOO69_RS17420	COG0739	heme binding
HOO69_RS17430	COG1063	alcohol dehydrogenase
HOO69_RS17450	COG1595	DNA-templated transcription, initiation
HOO69_RS17490	COG4964	Belongs to the GSP D family
HOO69_RS17500	COG0455	bacterial-type flagellum organization
HOO69_RS17525	COG2885	chlorophyll binding
HOO69_RS17530	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HOO69_RS17550	COG0596	Alpha beta hydrolase
HOO69_RS17560	COG4221	oxidoreductase activity
HOO69_RS17565	COG0471	metal ion transport
HOO69_RS17570	COG2988	succinylglutamate desuccinylase activity
HOO69_RS17575	COG0523	cobalamin synthesis protein
HOO69_RS17580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HOO69_RS17590	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HOO69_RS17610	COG2814	Major facilitator Superfamily
HOO69_RS17615	COG1902	pentaerythritol trinitrate reductase activity
HOO69_RS17620	COG1012	belongs to the aldehyde dehydrogenase family
HOO69_RS17655	COG0561	phosphatase activity
HOO69_RS17665	COG1454	alcohol dehydrogenase
HOO69_RS17670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HOO69_RS17680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HOO69_RS17690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HOO69_RS17695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HOO69_RS17695	COG1263	PTS System
HOO69_RS17695	COG2190	(PTS) system
HOO69_RS17705	COG0814	amino acid
HOO69_RS17710	COG2909	trisaccharide binding
HOO69_RS17715	COG0058	SHG alpha-glucan phosphorylase activity
HOO69_RS17720	COG1640	4-alpha-glucanotransferase
HOO69_RS17725	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HOO69_RS17755	COG3710	Transcriptional regulator
HOO69_RS17805	COG1741	Belongs to the pirin family
HOO69_RS17825	COG1132	(ABC) transporter
HOO69_RS17840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HOO69_RS17860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HOO69_RS17865	COG1120	ATPase activity
HOO69_RS17870	COG2814	Major facilitator Superfamily
HOO69_RS17885	COG0786	glutamate:sodium symporter activity
HOO69_RS17905	COG1247	-acetyltransferase
HOO69_RS17925	COG0137	argininosuccinate synthase activity
HOO69_RS17965	COG2814	Major facilitator Superfamily
HOO69_RS17975	COG0642	Histidine kinase
HOO69_RS17980	COG0745	RESPONSE REGULATOR receiver
HOO69_RS18005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HOO69_RS18020	COG0583	DNA-binding transcription factor activity
HOO69_RS18050	COG4533	DNA binding
HOO69_RS18055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HOO69_RS18065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HOO69_RS18070	COG1151	hydroxylamine reductase activity
HOO69_RS18080	COG0671	phosphoesterase, PA-phosphatase related
HOO69_RS18095	COG1494	fructose-1,6-bisphosphatase
HOO69_RS18100	COG0698	ribose 5-phosphate isomerase
HOO69_RS18105	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HOO69_RS18125	COG2376	Dihydroxyacetone kinase
HOO69_RS18130	COG1461	Dihydroxyacetone kinase
HOO69_RS18140	COG0679	Auxin Efflux Carrier
HOO69_RS18155	COG3604	Transcriptional regulator
HOO69_RS18175	COG2814	Major facilitator Superfamily
HOO69_RS18185	COG2329	Antibiotic biosynthesis monooxygenase
HOO69_RS18200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HOO69_RS18210	COG0583	DNA-binding transcription factor activity
HOO69_RS18225	COG2814	Major facilitator Superfamily
HOO69_RS18230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HOO69_RS18235	COG1940	carbohydrate kinase activity
HOO69_RS18240	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HOO69_RS18245	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HOO69_RS18250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HOO69_RS18255	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HOO69_RS18260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HOO69_RS18265	COG1737	Transcriptional regulator
HOO69_RS18270	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HOO69_RS18275	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HOO69_RS18280	COG4409	exo-alpha-(2->6)-sialidase activity
HOO69_RS18285	COG3706	GGDEF domain
HOO69_RS18295	COG4580	involved in the transport of maltose and maltodextrins
HOO69_RS18315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HOO69_RS18325	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HOO69_RS18330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HOO69_RS18340	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HOO69_RS18345	COG3366	ferrous iron transmembrane transporter activity
HOO69_RS18350	COG0700	Nucleoside recognition
HOO69_RS18355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HOO69_RS18360	COG0583	DNA-binding transcription factor activity
HOO69_RS18375	COG4774	siderophore transport
HOO69_RS18405	COG1280	lysine exporter protein (LysE YggA)
HOO69_RS18420	COG4232	protein-disulfide reductase activity
HOO69_RS18425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HOO69_RS18435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HOO69_RS18445	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HOO69_RS18450	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HOO69_RS18455	COG1845	cytochrome c oxidase, subunit III
HOO69_RS18475	COG1612	heme a metabolic process
HOO69_RS18480	COG0109	protoheme IX farnesyltransferase activity
HOO69_RS18490	COG0765	amino acid transport
HOO69_RS18495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HOO69_RS18500	COG0765	amino acid transport
HOO69_RS18505	COG1126	abc transporter atp-binding protein
HOO69_RS18510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HOO69_RS18520	COG4175	Glycine betaine
HOO69_RS18520	COG3448	diguanylate cyclase activity
HOO69_RS18525	COG4176	ABC-type proline glycine betaine transport system permease component
HOO69_RS18560	COG4964	Belongs to the GSP D family
HOO69_RS18570	COG2894	cell division
HOO69_RS18625	COG1477	protein flavinylation
HOO69_RS18645	COG4221	oxidoreductase activity
HOO69_RS18670	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HOO69_RS18675	COG1162	GTPase activity
HOO69_RS18685	COG1999	signal sequence binding
HOO69_RS18695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HOO69_RS18700	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HOO69_RS18705	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HOO69_RS18710	COG3033	Beta-eliminating lyase
HOO69_RS18750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HOO69_RS18775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOO69_RS18805	COG0840	transmembrane signaling receptor activity
HOO69_RS18810	COG0454	-acetyltransferase
HOO69_RS18835	COG1122	ATPase activity
HOO69_RS18845	COG1566	PFAM secretion protein HlyD family protein
HOO69_RS18855	COG3706	GGDEF domain
HOO69_RS18870	COG0813	purine-nucleoside phosphorylase activity
HOO69_RS18875	COG3272	Protein of unknown function (DUF1722)
HOO69_RS18880	COG0789	Transcriptional regulator
HOO69_RS18885	COG0415	Belongs to the DNA photolyase family
HOO69_RS18890	COG1388	LysM domain
HOO69_RS18890	COG1376	ErfK ybiS ycfS ynhG family protein
HOO69_RS18900	COG0513	Belongs to the DEAD box helicase family
HOO69_RS18910	COG0513	Belongs to the DEAD box helicase family
HOO69_RS18915	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
HOO69_RS18930	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HOO69_RS18940	COG0330	HflC and HflK could
HOO69_RS18950	COG2211	Major facilitator Superfamily
HOO69_RS18955	COG1486	melibiose metabolic process
HOO69_RS18960	COG2169	Transcriptional regulator
HOO69_RS18965	COG3842	ATPase activity
HOO69_RS18975	COG1175	transmembrane transport
HOO69_RS18980	COG3833	ABC-type maltose transport systems, permease component
HOO69_RS19030	COG0402	S-adenosylhomocysteine deaminase activity
HOO69_RS19035	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HOO69_RS19040	COG2239	Acts as a magnesium transporter
HOO69_RS19045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HOO69_RS19070	COG0121	glutamine amidotransferase
HOO69_RS19080	COG0531	amino acid
HOO69_RS19100	COG0673	inositol 2-dehydrogenase activity
HOO69_RS19105	COG1765	OsmC-like protein
HOO69_RS19135	COG2304	oxidoreductase activity
HOO69_RS19140	COG2304	oxidoreductase activity
HOO69_RS19155	COG0714	Associated with various cellular activities
HOO69_RS19175	COG0583	DNA-binding transcription factor activity
HOO69_RS19200	COG3706	GGDEF domain
HOO69_RS19210	COG0401	homolog of Blt101
HOO69_RS19215	COG3217	Mosc domain protein beta barrel domain protein
HOO69_RS19215	COG0633	Ferredoxin
HOO69_RS19215	COG3217	Mosc domain protein beta barrel domain protein
HOO69_RS19215	COG0633	Ferredoxin
HOO69_RS19220	COG3706	GGDEF domain
HOO69_RS19235	COG0747	negative chemotaxis
HOO69_RS19240	COG0601	transmembrane transport
HOO69_RS19250	COG4172	Belongs to the ABC transporter superfamily
HOO69_RS19265	COG0366	Alpha amylase catalytic
HOO69_RS19290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HOO69_RS19300	COG5001	Diguanylate cyclase
HOO69_RS19300	COG3300	MHYT domain
HOO69_RS19305	COG0583	DNA-binding transcription factor activity
HOO69_RS19310	COG2814	Major facilitator Superfamily
HOO69_RS19330	COG0697	spore germination
HOO69_RS19340	COG0534	Mate efflux family protein
HOO69_RS19350	COG2249	NAD(P)H dehydrogenase (quinone) activity
HOO69_RS19365	COG3604	Transcriptional regulator
HOO69_RS19370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HOO69_RS19370	COG1017	nitric oxide dioxygenase activity
HOO69_RS19385	COG1278	Cold shock
HOO69_RS19390	COG3036	rescue of stalled ribosome
HOO69_RS19405	COG1686	Belongs to the peptidase S11 family
HOO69_RS19425	COG3530	Putative quorum-sensing-regulated virulence factor
HOO69_RS19440	COG4941	Belongs to the sigma-70 factor family
HOO69_RS19445	COG3795	YCII-related domain
HOO69_RS19450	COG1454	alcohol dehydrogenase
HOO69_RS19455	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HOO69_RS19465	COG1011	Hydrolase
HOO69_RS19505	COG1840	ABC-type Fe3 transport system, periplasmic component
HOO69_RS19515	COG3842	ATPase activity
HOO69_RS19545	COG2866	Carboxypeptidase
HOO69_RS19550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HOO69_RS19555	COG0583	DNA-binding transcription factor activity
HOO69_RS19560	COG1760	l-serine dehydratase
HOO69_RS19580	COG3706	GGDEF domain
HOO69_RS19585	COG0784	Response regulator, receiver
HOO69_RS19585	COG0835	chemotaxis
HOO69_RS19590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HOO69_RS19595	COG0737	Belongs to the 5'-nucleotidase family
HOO69_RS19610	COG0494	nUDIX hydrolase
HOO69_RS19620	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HOO69_RS19625	COG2814	Major facilitator Superfamily
HOO69_RS19645	COG2199	diguanylate cyclase activity
HOO69_RS19650	COG1846	Transcriptional regulator
HOO69_RS19655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HOO69_RS19660	COG5002	protein histidine kinase activity
HOO69_RS19660	COG2176	DNA-directed DNA polymerase activity
HOO69_RS19670	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HOO69_RS19690	COG0004	ammonium transporteR
HOO69_RS19695	COG4607	ABC-type enterochelin transport system periplasmic component
HOO69_RS19700	COG4206	TonB-dependent receptor
HOO69_RS19730	COG0840	transmembrane signaling receptor activity
HOO69_RS19750	COG0840	transmembrane signaling receptor activity
HOO69_RS19770	COG1115	amino acid carrier protein
HOO69_RS19785	COG0840	transmembrane signaling receptor activity
HOO69_RS19790	COG2203	Gaf domain
HOO69_RS19790	COG2199	diguanylate cyclase activity
HOO69_RS19810	COG3706	GGDEF domain
HOO69_RS19825	COG1024	Enoyl-CoA hydratase
HOO69_RS19830	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HOO69_RS19835	COG1960	acyl-CoA dehydrogenase activity
HOO69_RS19845	COG0183	Belongs to the thiolase family
HOO69_RS19855	COG1960	acyl-CoA dehydrogenase activity
HOO69_RS19860	COG1024	Enoyl-CoA hydratase
HOO69_RS19865	COG1024	Enoyl-CoA hydratase
HOO69_RS19875	COG1028	Short-chain dehydrogenase reductase Sdr
HOO69_RS19880	COG0840	transmembrane signaling receptor activity
HOO69_RS19890	COG2315	Protein conserved in bacteria
HOO69_RS19900	COG0583	DNA-binding transcription factor activity
HOO69_RS19905	COG0277	FAD linked oxidase domain protein
HOO69_RS19920	COG5002	protein histidine kinase activity
HOO69_RS19920	COG5001	Diguanylate cyclase
HOO69_RS19935	COG0243	molybdopterin cofactor binding
HOO69_RS19940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HOO69_RS19940	COG1648	precorrin-2 dehydrogenase activity
HOO69_RS19945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HOO69_RS19955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HOO69_RS19955	COG1116	anion transmembrane transporter activity
HOO69_RS19960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HOO69_RS19965	COG1116	anion transmembrane transporter activity
HOO69_RS19970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HOO69_RS19970	COG2146	nitrite reductase [NAD(P)H] activity
HOO69_RS19980	COG2197	response regulator
HOO69_RS20030	COG3118	belongs to the thioredoxin family
HOO69_RS20035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HOO69_RS20040	COG0420	3'-5' exonuclease activity
HOO69_RS20045	COG0419	ATPase involved in DNA repair
HOO69_RS20050	COG0784	Response regulator, receiver
HOO69_RS20050	COG2205	protein histidine kinase activity
HOO69_RS20055	COG0156	8-amino-7-oxononanoate synthase activity
HOO69_RS20065	COG0038	chloride channel
HOO69_RS20070	COG0523	cobalamin synthesis protein
HOO69_RS20075	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HOO69_RS20085	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HOO69_RS20150	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HOO69_RS20155	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HOO69_RS20215	COG0840	transmembrane signaling receptor activity
HOO69_RS20220	COG4166	transmembrane transport
HOO69_RS20225	COG4174	ABC transporter (Permease)
HOO69_RS20230	COG4239	(ABC) transporter, permease
HOO69_RS20235	COG4172	Belongs to the ABC transporter superfamily
HOO69_RS20245	COG5001	Diguanylate cyclase
HOO69_RS20275	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOO69_RS20280	COG4605	iron ion homeostasis
HOO69_RS20285	COG4604	ABC transporter, ATP-binding protein
HOO69_RS20290	COG0789	Transcriptional regulator
HOO69_RS20310	COG5001	Diguanylate cyclase
HOO69_RS20310	COG3300	MHYT domain
HOO69_RS20315	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOO69_RS20430	COG1742	UPF0060 membrane protein
HOO69_RS20485	COG3152	Membrane
HOO69_RS20505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HOO69_RS20540	COG0625	glutathione transferase activity
HOO69_RS20565	COG4628	conserved protein (DUF2132)
HOO69_RS20590	COG1309	transcriptional regulator
HOO69_RS20595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HOO69_RS20615	COG0183	Belongs to the thiolase family
HOO69_RS20630	COG1794	racemase activity, acting on amino acids and derivatives
HOO69_RS20635	COG2814	Major facilitator Superfamily
HOO69_RS20640	COG3240	lipase activity
HOO69_RS20720	COG1328	CTP reductase activity
HOO69_RS20725	COG0602	queuosine metabolic process
HOO69_RS20735	COG4067	protein conserved in archaea
HOO69_RS20735	COG0189	ligase activity
HOO69_RS20740	COG0494	nUDIX hydrolase
HOO69_RS20745	COG0545	Peptidyl-prolyl cis-trans isomerase
HOO69_RS20770	COG2926	Belongs to the UPF0265 family
HOO69_RS20785	COG2827	Endonuclease containing a URI domain
HOO69_RS20795	COG1879	ABC-type sugar transport system periplasmic component
HOO69_RS20800	COG0784	Response regulator, receiver
HOO69_RS20800	COG2205	protein histidine kinase activity
HOO69_RS20820	COG1289	transmembrane transporter activity
HOO69_RS20825	COG0210	DNA helicase
HOO69_RS20845	COG0484	heat shock protein binding
HOO69_RS20855	COG1116	anion transmembrane transporter activity
HOO69_RS20860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HOO69_RS20865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HOO69_RS20875	COG1716	ATPase activity
HOO69_RS20875	COG5001	Diguanylate cyclase
HOO69_RS20880	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HOO69_RS20890	COG4181	ATPase activity
HOO69_RS20905	COG1984	allophanate hydrolase subunit 2
HOO69_RS20915	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HOO69_RS20920	COG3300	MHYT domain
HOO69_RS20920	COG5001	Diguanylate cyclase
HOO69_RS20955	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HOO69_RS20955	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HOO69_RS20960	COG3850	Histidine kinase
HOO69_RS20965	COG2197	response regulator
HOO69_RS20970	COG3069	C4-dicarboxylate transmembrane transporter activity
HOO69_RS20995	COG3038	cytochrome b561
HOO69_RS21000	COG2353	YceI-like domain
HOO69_RS21005	COG2116	formate transmembrane transporter activity
HOO69_RS21010	COG0583	DNA-binding transcription factor activity
HOO69_RS21020	COG3593	DNA synthesis involved in DNA repair
HOO69_RS21025	COG0737	Belongs to the 5'-nucleotidase family
HOO69_RS21055	COG0750	zinc metalloprotease
HOO69_RS21060	COG4783	chaperone-mediated protein folding
HOO69_RS21065	COG2050	protein possibly involved in aromatic compounds catabolism
HOO69_RS21085	COG4771	TonB-dependent receptor
HOO69_RS21085	COG1629	transport
HOO69_RS21090	COG0583	DNA-binding transcription factor activity
HOO69_RS21100	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HOO69_RS21105	COG0363	glucosamine-6-phosphate deaminase activity
HOO69_RS21110	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HOO69_RS21115	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HOO69_RS21145	COG0156	8-amino-7-oxononanoate synthase activity
HOO69_RS21185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HOO69_RS21210	COG5001	Diguanylate cyclase
HOO69_RS21210	COG1716	ATPase activity
HOO69_RS21215	COG0798	PFAM Bile acid sodium symporter
HOO69_RS21225	COG0045	succinate-CoA ligase (ADP-forming) activity
HOO69_RS21225	COG1042	CoA-binding domain protein
HOO69_RS21225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HOO69_RS21235	COG1181	Belongs to the D-alanine--D-alanine ligase family
HOO69_RS21250	COG0023	Translation Initiation Factor
HOO69_RS21410	COG3140	Belongs to the UPF0181 family
HOO69_RS21425	COG0745	RESPONSE REGULATOR receiver
HOO69_RS21435	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HOO69_RS21440	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HOO69_RS21455	COG3706	GGDEF domain
HOO69_RS21460	COG4251	negative regulation of phosphorylation
HOO69_RS21460	COG3706	GGDEF domain
HOO69_RS21460	COG5001	Diguanylate cyclase
HOO69_RS21460	COG2203	Gaf domain
HOO69_RS21470	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HOO69_RS21475	COG4149	molybdate abc transporter
HOO69_RS21480	COG0725	ABC transporter, periplasmic molybdate-binding protein
HOO69_RS21485	COG1492	cobalamin metabolic process
HOO69_RS21490	COG3111	PFAM Bacterial OB fold (BOF) protein
HOO69_RS21500	COG1609	Transcriptional regulator
HOO69_RS21505	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HOO69_RS21505	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HOO69_RS21510	COG1105	Belongs to the carbohydrate kinase PfkB family
HOO69_RS21515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HOO69_RS21515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HOO69_RS21515	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HOO69_RS21520	COG3706	GGDEF domain
HOO69_RS21525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HOO69_RS21535	COG2207	Transcriptional regulator
HOO69_RS21540	COG1979	alcohol dehydrogenase
HOO69_RS21555	COG2205	protein histidine kinase activity
HOO69_RS21555	COG2198	Histidine kinase
HOO69_RS21555	COG0784	Response regulator, receiver
HOO69_RS21560	COG1879	ABC-type sugar transport system periplasmic component
HOO69_RS21565	COG1803	Methylglyoxal synthase
HOO69_RS21575	COG0546	phosphoglycolate phosphatase activity
HOO69_RS21590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HOO69_RS21595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HOO69_RS21620	COG0456	acetyltransferase
HOO69_RS21620	COG1214	PFAM Peptidase M22, glycoprotease
HOO69_RS21640	COG0513	Belongs to the DEAD box helicase family
HOO69_RS21650	COG0814	amino acid
HOO69_RS21655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOO69_RS21655	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOO69_RS21670	COG0513	Belongs to the DEAD box helicase family
HOO69_RS21680	COG0303	'Molybdopterin
HOO69_RS21685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HOO69_RS21700	COG2897	thiosulfate sulfurtransferase activity
HOO69_RS21755	COG4964	Belongs to the GSP D family
HOO69_RS21775	COG0583	DNA-binding transcription factor activity
HOO69_RS21790	COG0583	DNA-binding transcription factor activity
HOO69_RS21805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HOO69_RS21810	COG1522	sequence-specific DNA binding
HOO69_RS21815	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HOO69_RS21825	COG0840	transmembrane signaling receptor activity
HOO69_RS21835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOO69_RS21840	COG1067	ATP-dependent peptidase activity
HOO69_RS21850	COG4172	Belongs to the ABC transporter superfamily
HOO69_RS21860	COG0583	DNA-binding transcription factor activity
HOO69_RS21865	COG1620	l-lactate permease
HOO69_RS21870	COG1304	FMN binding
HOO69_RS21925	COG0463	Glycosyl transferase, family 2
HOO69_RS21950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HOO69_RS21970	COG3284	Transcriptional regulator
HOO69_RS21975	COG1012	belongs to the aldehyde dehydrogenase family
HOO69_RS22015	COG2205	protein histidine kinase activity
HOO69_RS22020	COG1263	PTS System
HOO69_RS22020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HOO69_RS22025	COG4175	Glycine betaine
HOO69_RS22045	COG1012	belongs to the aldehyde dehydrogenase family
HOO69_RS22055	COG0784	Response regulator, receiver
HOO69_RS22055	COG2205	protein histidine kinase activity
HOO69_RS22055	COG5002	protein histidine kinase activity
HOO69_RS22060	COG0745	RESPONSE REGULATOR receiver
HOO69_RS22080	COG4774	siderophore transport
HOO69_RS22095	COG3251	PFAM MbtH domain protein
HOO69_RS22100	COG4615	Cyclic peptide transporter
HOO69_RS22110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HOO69_RS22115	COG1120	ATPase activity
HOO69_RS22155	COG1121	(ABC) transporter
HOO69_RS22160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HOO69_RS22200	COG0516	GMP reductase activity
HOO69_RS22210	COG0516	GMP reductase activity
HOO69_RS22220	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HOO69_RS22235	COG2375	cellular response to nickel ion
HOO69_RS22240	COG0583	DNA-binding transcription factor activity
HOO69_RS22250	COG0564	pseudouridine synthase activity
HOO69_RS22275	COG0513	Belongs to the DEAD box helicase family
HOO69_RS22285	COG3706	GGDEF domain
HOO69_RS22290	COG1309	transcriptional regulator
HOO69_RS22295	COG2130	NADP-dependent
HOO69_RS22310	COG2084	Dehydrogenase
HOO69_RS22325	COG0366	Alpha amylase catalytic
HOO69_RS22330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HOO69_RS22335	COG0625	glutathione transferase activity
HOO69_RS22375	COG0745	RESPONSE REGULATOR receiver
HOO69_RS22395	COG1309	transcriptional regulator
HOO69_RS22430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HOO69_RS22435	COG3300	MHYT domain
HOO69_RS22435	COG5001	Diguanylate cyclase
HOO69_RS22460	COG1271	oxidase subunit
HOO69_RS22465	COG1294	oxidase, subunit
HOO69_RS22510	COG4969	Belongs to the N-Me-Phe pilin family
HOO69_RS22515	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HOO69_RS22530	COG1357	PFAM Pentapeptide repeats (8 copies)
HOO69_RS22545	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HOO69_RS22585	COG0443	Heat shock 70 kDa protein
HOO69_RS22590	COG0583	DNA-binding transcription factor activity
HOO69_RS22600	COG4948	Mandelate Racemase Muconate Lactonizing
HOO69_RS22620	COG0366	Alpha amylase catalytic
HOO69_RS22625	COG2182	Extracellular solute-binding protein
HOO69_RS22635	COG0366	Alpha amylase catalytic
HOO69_RS22650	COG3275	phosphorelay sensor kinase activity
HOO69_RS22665	COG4591	ABC-type transport system involved in lipoprotein release permease component
HOO69_RS22670	COG1136	(ABC) transporter
HOO69_RS22690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HOO69_RS22695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HOO69_RS22735	COG2154	pterin-4-alpha-carbinolamine dehydratase
HOO69_RS22740	COG3186	Phenylalanine-4-hydroxylase
HOO69_RS22745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HOO69_RS22765	COG0384	phenazine biosynthesis protein PhzF
HOO69_RS22785	COG2226	methyltransferase
HOO69_RS22810	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HOO69_RS22820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HOO69_RS22825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HOO69_RS22825	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HOO69_RS22835	COG0745	RESPONSE REGULATOR receiver
HOO69_RS22840	COG3437	response regulator, receiver
HOO69_RS22845	COG3437	response regulator, receiver
HOO69_RS22845	COG3850	Histidine kinase
HOO69_RS22845	COG4999	Histidine kinase
HOO69_RS22845	COG2205	protein histidine kinase activity
HOO69_RS22855	COG2172	sigma factor antagonist activity
HOO69_RS22865	COG1366	Belongs to the anti-sigma-factor antagonist family
HOO69_RS22870	COG0840	transmembrane signaling receptor activity
HOO69_RS22910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HOO69_RS22920	COG2096	Adenosyltransferase
HOO69_RS22925	COG0748	coenzyme F420 binding
HOO69_RS22930	COG3721	Heme iron utilization protein
HOO69_RS22940	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HOO69_RS22945	COG0811	peptide transport
HOO69_RS22950	COG0848	biopolymer transport protein
HOO69_RS22960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOO69_RS22965	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HOO69_RS22985	COG3047	cAMP biosynthetic process
HOO69_RS22990	COG0739	heme binding
HOO69_RS23025	COG2203	Gaf domain
HOO69_RS23025	COG2199	diguanylate cyclase activity
HOO69_RS23060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HOO69_RS23065	COG0581	inorganic phosphate transmembrane transporter activity
HOO69_RS23070	COG0573	inorganic phosphate transmembrane transporter activity
HOO69_RS23080	COG0840	transmembrane signaling receptor activity
HOO69_RS23095	COG0835	chemotaxis
HOO69_RS23095	COG0784	Response regulator, receiver
HOO69_RS23105	COG4191	Histidine kinase
HOO69_RS23105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HOO69_RS23110	COG3437	response regulator, receiver
HOO69_RS23110	COG0784	Response regulator, receiver
HOO69_RS23115	COG1609	Transcriptional regulator
HOO69_RS23120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HOO69_RS23125	COG1879	ABC-type sugar transport system periplasmic component
HOO69_RS23130	COG1172	Belongs to the binding-protein-dependent transport system permease family
HOO69_RS23135	COG1129	ABC transporter
HOO69_RS23140	COG1869	D-ribose catabolic process
HOO69_RS23150	COG0004	ammonium transporteR
HOO69_RS23170	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HOO69_RS23180	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HOO69_RS23185	COG0509	glycine decarboxylation via glycine cleavage system
HOO69_RS23200	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HOO69_RS23220	COG4191	Histidine kinase
HOO69_RS23220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HOO69_RS23245	COG1396	sequence-specific DNA binding
HOO69_RS23255	COG1280	lysine exporter protein (LysE YggA)
HOO69_RS23270	COG3501	Rhs element vgr protein
HOO69_RS23330	COG1609	Transcriptional regulator
HOO69_RS23335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HOO69_RS23340	COG3265	gluconokinase activity
HOO69_RS23345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HOO69_RS23350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HOO69_RS23355	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HOO69_RS23395	COG1032	radical SAM domain protein
HOO69_RS23415	COG0668	transmembrane transport
HOO69_RS23420	COG2211	Major facilitator Superfamily
HOO69_RS23435	COG0366	Alpha amylase catalytic
HOO69_RS23495	COG4191	Histidine kinase
HOO69_RS23495	COG0784	Response regulator, receiver
HOO69_RS23505	COG0561	phosphatase activity
HOO69_RS23510	COG0346	lactoylglutathione lyase activity
HOO69_RS23525	COG0456	acetyltransferase
HOO69_RS23565	COG0697	spore germination
HOO69_RS23600	COG3706	GGDEF domain
HOO69_RS23605	COG0488	(ABC) transporter
HOO69_RS23610	COG0348	domain, Protein
HOO69_RS23615	COG0437	4 iron, 4 sulfur cluster binding
HOO69_RS23620	COG3383	formate dehydrogenase (NAD+) activity
HOO69_RS23660	COG1683	Conserved Protein
HOO69_RS23685	COG0183	Belongs to the thiolase family
HOO69_RS23690	COG1028	Short-chain dehydrogenase reductase Sdr
HOO69_RS23715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HOO69_RS23740	COG0346	lactoylglutathione lyase activity
HOO69_RS23765	COG3300	MHYT domain
HOO69_RS23765	COG5001	Diguanylate cyclase
HOO69_RS23780	COG2814	Major facilitator Superfamily
HOO69_RS23790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HOO69_RS23795	COG2423	ornithine cyclodeaminase activity
HOO69_RS23800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HOO69_RS23800	COG2022	thiamine diphosphate biosynthetic process
HOO69_RS23805	COG3938	Belongs to the proline racemase family
HOO69_RS23825	COG0745	RESPONSE REGULATOR receiver
HOO69_RS23835	COG1653	transport
HOO69_RS23845	COG5002	protein histidine kinase activity
HOO69_RS23845	COG5001	Diguanylate cyclase
HOO69_RS23875	COG0601	transmembrane transport
HOO69_RS23880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOO69_RS23900	COG4628	conserved protein (DUF2132)
HOO69_RS23905	COG0024	Methionine aminopeptidase
HOO69_RS23935	COG2186	Transcriptional regulator
HOO69_RS23945	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HOO69_RS23955	COG0246	Mannitol dehydrogenase
HOO69_RS23965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HOO69_RS23970	COG0800	Aldolase
HOO69_RS24025	COG3568	Endonuclease Exonuclease Phosphatase
HOO69_RS24030	COG3291	Pkd domain containing protein
HOO69_RS24040	COG1028	Short-chain dehydrogenase reductase Sdr
HOO69_RS24070	COG1671	Belongs to the UPF0178 family
HOO69_RS24075	COG1280	lysine exporter protein (LysE YggA)
HOO69_RS24080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOO69_RS24085	COG1301	dicarboxylic acid transport
HOO69_RS24090	COG2200	EAL domain
HOO69_RS24090	COG2199	diguanylate cyclase activity
HOO69_RS24125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOO69_RS24130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOO69_RS24155	COG2986	histidine ammonia-lyase
HOO69_RS24180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HOO69_RS24185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HOO69_RS24190	COG1028	Short-chain dehydrogenase reductase Sdr
HOO69_RS24200	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HOO69_RS24210	COG1278	Cold shock
HOO69_RS24215	COG3122	Protein conserved in bacteria
HOO69_RS24220	COG1166	arginine decarboxylase activity
HOO69_RS24225	COG0010	Belongs to the arginase family
HOO69_RS24260	COG2186	Transcriptional regulator
HOO69_RS24280	COG0402	S-adenosylhomocysteine deaminase activity
HOO69_RS24285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HOO69_RS24290	COG0840	transmembrane signaling receptor activity
HOO69_RS24295	COG5002	protein histidine kinase activity
HOO69_RS24295	COG2205	protein histidine kinase activity
HOO69_RS24295	COG0784	Response regulator, receiver
HOO69_RS24310	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HOO69_RS24325	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HOO69_RS24330	COG0804	urea catabolic process
HOO69_RS24335	COG0832	Belongs to the urease beta subunit family
HOO69_RS24340	COG0831	urea catabolic process
HOO69_RS24365	COG0559	Belongs to the binding-protein-dependent transport system permease family
HOO69_RS24375	COG1404	Belongs to the peptidase S8 family
HOO69_RS24385	COG0840	transmembrane signaling receptor activity
HOO69_RS24395	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HOO69_RS24400	COG4266	Belongs to the allantoicase family
HOO69_RS24420	COG2252	PERMEase
HOO69_RS24485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HOO69_RS24490	COG1609	Transcriptional regulator
HOO69_RS24500	COG1280	lysine exporter protein (LysE YggA)
HOO69_RS24515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HOO69_RS24525	COG1012	belongs to the aldehyde dehydrogenase family
HOO69_RS24540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HOO69_RS24545	COG1482	cell wall glycoprotein biosynthetic process
HOO69_RS24550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HOO69_RS24550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HOO69_RS24550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HOO69_RS24560	COG0383	alpha-mannosidase activity
HOO69_RS24565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HOO69_RS24565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HOO69_RS24565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HOO69_RS24585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HOO69_RS24590	COG3394	polysaccharide catabolic process
HOO69_RS24610	COG3453	Protein conserved in bacteria
HOO69_RS24610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HOO69_RS24620	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
HOO69_RS24625	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HOO69_RS24635	COG1733	regulation of RNA biosynthetic process
HOO69_RS24650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOO69_RS24665	COG1418	mRNA catabolic process
HOO69_RS24680	COG2814	Major facilitator Superfamily
HOO69_RS24700	COG3639	organic phosphonate transmembrane transporter activity
HOO69_RS24705	COG3639	organic phosphonate transmembrane transporter activity
HOO69_RS24710	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HOO69_RS24760	COG0242	peptide deformylase activity
HOO69_RS24770	COG0596	Alpha beta hydrolase
HOO69_RS24775	COG0583	DNA-binding transcription factor activity
HOO69_RS24780	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HOO69_RS24785	COG0569	domain protein
HOO69_RS24795	COG2205	protein histidine kinase activity
HOO69_RS24815	COG2706	6-phosphogluconolactonase activity
HOO69_RS24825	COG0800	Aldolase
HOO69_RS24835	COG4145	pantothenate transmembrane transporter activity
HOO69_RS24845	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HOO69_RS24865	COG1131	(ABC) transporter
HOO69_RS24870	COG2188	Transcriptional regulator
HOO69_RS24890	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HOO69_RS24895	COG3716	PTS system mannose fructose sorbose family IID component
HOO69_RS24905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HOO69_RS24910	COG2222	sugar isomerase
HOO69_RS24920	COG1349	DNA-binding transcription factor activity
HOO69_RS24925	COG1349	DNA-binding transcription factor activity
HOO69_RS24940	COG1136	(ABC) transporter
HOO69_RS24975	COG0446	pyridine nucleotide-disulphide oxidoreductase
HOO69_RS24995	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HOO69_RS25005	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HOO69_RS25010	COG0527	aspartate kinase activity
HOO69_RS25015	COG0662	Cupin 2, conserved barrel domain protein
HOO69_RS25020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HOO69_RS25025	COG0456	acetyltransferase
HOO69_RS25035	COG1917	Cupin 2, conserved barrel domain protein
HOO69_RS25035	COG4977	sequence-specific DNA binding
HOO69_RS25040	COG1280	lysine exporter protein (LysE YggA)
HOO69_RS25045	COG1522	sequence-specific DNA binding
HOO69_RS25055	COG2258	MOSC domain
HOO69_RS25060	COG1609	Transcriptional regulator
HOO69_RS25065	COG1757	Na H antiporter
HOO69_RS25070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities