locus-tag	class	description
GPY22_RS00010	ENOG4108Z86	Glutamine amidotransferase
GPY22_RS00020	ENOG4107S6Z	Na H antiporter
GPY22_RS00030	ENOG4105CQ7	ATP-dependent helicase
GPY22_RS00035	ENOG4107R1I	NAD-dependent malic enzyme
GPY22_RS00060	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
GPY22_RS00075	ENOG4108ZHR	arsR family transcriptional regulator
GPY22_RS00090	ENOG4108Z4X	TRANSCRIPTIONal
GPY22_RS00100	ENOG4107GZ4	SanA protein
GPY22_RS00110	ENOG4108FUF	Transcriptional regulator, IclR family
GPY22_RS00115	ENOG4108FUF	Transcriptional regulator, IclR family
GPY22_RS00120	ENOG4105C26	Dehydrogenase
GPY22_RS00125	ENOG4105C0A	alcohol dehydrogenase
GPY22_RS00150	ENOG4105C3M	thioredoxin reductase
GPY22_RS00170	ENOG4105FE9	pseudouridine synthase
GPY22_RS00175	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GPY22_RS00180	ENOG4105DB7	PHP domain protein
GPY22_RS00195	ENOG4105DDQ	anthranilate synthase
GPY22_RS00200	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GPY22_RS00205	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GPY22_RS00210	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GPY22_RS00215	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GPY22_RS00220	ENOG4105CK2	sodium dicarboxylate symporter
GPY22_RS00230	ENOG4107835	probably involved in intracellular septation (By similarity)
GPY22_RS00235	ENOG4105NAU	thioesterase Superfamily protein
GPY22_RS00240	ENOG4105K9H	YciI-like protein
GPY22_RS00255	ENOG4105DZ2	Transcriptional regulator
GPY22_RS00340	ENOG4108TFU	terminase (Small subunit)
GPY22_RS00360	ENOG4105KUS	lysozyme
GPY22_RS00375	ENOG4105RWQ	Protein of unknown function (DUF1364)
GPY22_RS00430	ENOG4106CVF	DNA replication protein
GPY22_RS00525	ENOG4105DH7	May be involved in recombination (By similarity)
GPY22_RS00540	ENOG4108I1J	Integrase
GPY22_RS00575	ENOG4108K3A	Glutathione S-transferase
GPY22_RS00590	ENOG4108N3W	hemolysin secretion protein
GPY22_RS00610	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
GPY22_RS00615	ENOG4105BZU	Histidine kinase
GPY22_RS00620	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GPY22_RS00640	ENOG4105C5H	ABC transporter
GPY22_RS00645	ENOG4105CCT	upf0313 protein
GPY22_RS00650	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GPY22_RS00660	ENOG4105CUX	Signal transduction histidine kinase
GPY22_RS00685	ENOG4105DWU	Membrane
GPY22_RS00700	ENOG4106KNT	transcriptional regulator
GPY22_RS00705	ENOG4108EKI	Dehydrogenase
GPY22_RS00710	ENOG41090BQ	Glutaredoxin
GPY22_RS00725	ENOG4107QPN	acyl-Coa dehydrogenase
GPY22_RS00730	ENOG41067SE	Tetr family transcriptional regulator
GPY22_RS00745	ENOG4105C26	Dehydrogenase
GPY22_RS00755	ENOG4108RNS	Exports L-alanine (By similarity)
GPY22_RS00770	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GPY22_RS00775	ENOG4105UFD	tol-pal system protein YbgF
GPY22_RS00780	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GPY22_RS00795	ENOG4105M8F	Biopolymer transport protein exbD tolR
GPY22_RS00800	ENOG4105E02	MotA TolQ exbB proton channel
GPY22_RS00825	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GPY22_RS00830	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GPY22_RS00835	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GPY22_RS00840	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GPY22_RS00850	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GPY22_RS00855	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GPY22_RS00860	ENOG4105D58	Diguanylate phosphodiesterase
GPY22_RS00865	ENOG4105K5B	UPF0225 protein
GPY22_RS00875	ENOG4105ZU8	porin-like protein H
GPY22_RS00880	ENOG4105DVT	helicase
GPY22_RS00885	ENOG4108URS	primosomal replication protein n''
GPY22_RS00890	ENOG4106428	Protein of unknown function (DUF2496)
GPY22_RS00900	ENOG4105CGK	Exodeoxyribonuclease III
GPY22_RS00910	ENOG4105DSP	amino acid AbC transporter
GPY22_RS00930	ENOG4105C6N	Formate acetyltransferase
GPY22_RS00945	ENOG4105F1A	Pyruvate formate-lyase
GPY22_RS00955	ENOG4105XWI	UPF0304 protein
GPY22_RS00965	ENOG4105CYN	Serine protein kinase
GPY22_RS00970	ENOG4106AKX	UPF0229 protein
GPY22_RS00975	ENOG4105ED1	spovr family
GPY22_RS00980	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GPY22_RS00985	ENOG4105W49	UPF0434 protein
GPY22_RS00990	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GPY22_RS00995	ENOG4105BZ1	(ABC) transporter
GPY22_RS01000	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
GPY22_RS01010	ENOG4105D60	lipoprotein releasing system transmembrane protein
GPY22_RS01015	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GPY22_RS01045	ENOG4105CEP	NADH dehydrogenase
GPY22_RS01050	ENOG4105D0Y	UPF0227 protein
GPY22_RS01075	ENOG4105K59	histidine triad (HIT) protein
GPY22_RS01080	ENOG4108NVR	Methyl-accepting chemotaxis
GPY22_RS01090	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
GPY22_RS01100	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GPY22_RS01110	ENOG4105EW9	transcriptional regulator AsnC family
GPY22_RS01115	ENOG4105DCF	alanine dehydrogenase
GPY22_RS01125	ENOG4107R11	Transcriptional regulator
GPY22_RS01145	ENOG4105CFV	Tetratricopeptide repeat protein
GPY22_RS01150	ENOG4105Q4A	inner membrane protein yciS
GPY22_RS01155	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GPY22_RS01165	ENOG4105CAT	Cytidine monophosphate kinase
GPY22_RS01170	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
GPY22_RS01180	ENOG4105K70	DNA-binding protein
GPY22_RS01185	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GPY22_RS01190	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GPY22_RS01195	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GPY22_RS01200	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GPY22_RS01220	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
GPY22_RS01225	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GPY22_RS01230	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GPY22_RS01250	ENOG4105CNG	UPF0061 protein
GPY22_RS01255	ENOG4105EJQ	L-serine dehydratase
GPY22_RS01285	ENOG4108HPI	phosphatidate Cytidylyltransferase
GPY22_RS01295	ENOG4105DP0	ferredoxin-NADP reductase
GPY22_RS01320	ENOG4108KX4	response regulator
GPY22_RS01325	ENOG4105BZU	Histidine kinase
GPY22_RS01330	ENOG4105CXY	transporter
GPY22_RS01340	ENOG4107RCV	ABC transporter, permease
GPY22_RS01345	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPY22_RS01355	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GPY22_RS01360	ENOG4105D9N	nucleoside
GPY22_RS01365	ENOG4105EXG	Transcriptional regulator
GPY22_RS01370	ENOG4105CVE	Lytic murein transglycosylase
GPY22_RS01375	ENOG4105VNG	YcgL domain-containing protein
GPY22_RS01380	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GPY22_RS01385	ENOG4107QMS	site-determining protein
GPY22_RS01390	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GPY22_RS01400	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
GPY22_RS01405	ENOG4105CEY	Amp-dependent synthetase and ligase
GPY22_RS01425	ENOG41072GX	Peptidase M22 Glycoprotease
GPY22_RS01440	ENOG4105CIY	formyltetrahydrofolate deformylase
GPY22_RS01445	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GPY22_RS01455	ENOG4105HDK	L-asparaginase
GPY22_RS01460	ENOG4105VUT	cytoplasmic protein
GPY22_RS01470	ENOG4105E0X	reductase
GPY22_RS01475	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GPY22_RS01480	ENOG4105DSB	aldose 1-epimerase
GPY22_RS01485	ENOG4105DHI	Methyltransferase
GPY22_RS01510	ENOG4105KRS	Proteinase inhibitor
GPY22_RS01515	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GPY22_RS01520	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GPY22_RS01525	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GPY22_RS01530	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GPY22_RS01535	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GPY22_RS01540	ENOG4105WD1	Membrane
GPY22_RS01550	ENOG4105I93	response regulator
GPY22_RS01555	ENOG4105EJC	lysr family transcriptional regulator
GPY22_RS01560	ENOG41069NU	Nitroreductase
GPY22_RS01565	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GPY22_RS01570	ENOG4105CHU	acetyl-coa acetyltransferase
GPY22_RS01585	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GPY22_RS01605	ENOG4107SDU	Methyl-accepting chemotaxis
GPY22_RS01610	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
GPY22_RS01615	ENOG4108GAE	asmA family
GPY22_RS01620	ENOG4105DBI	uridine monophosphokinase
GPY22_RS01625	ENOG4105D1F	ATP-binding protein
GPY22_RS01640	ENOG4108I5U	Uridine phosphorylase
GPY22_RS01650	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GPY22_RS01655	ENOG4105BZU	Histidine kinase
GPY22_RS01660	ENOG4108ZAF	Molybdopterin
GPY22_RS01665	ENOG4105M00	molybdopterin converting factor, subunit 1
GPY22_RS01675	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GPY22_RS01680	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GPY22_RS01685	ENOG4105CHW	UPF0052 protein
GPY22_RS01700	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GPY22_RS01710	ENOG4105DFP	Integrase
GPY22_RS01715	ENOG4108YGG	dna repair protein
GPY22_RS01755	ENOG4105N0V	mono-oxygenase ydhR
GPY22_RS01760	ENOG4105CR8	Transcriptional regulator
GPY22_RS01770	ENOG4105CHR	reductase
GPY22_RS01775	ENOG4105F27	Major Facilitator
GPY22_RS01785	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GPY22_RS01805	ENOG4108R3D	Electron transport complex
GPY22_RS01815	ENOG4105D6A	Electron transport complex
GPY22_RS01820	ENOG4108UQQ	Electron transport complex
GPY22_RS01825	ENOG4105DZB	Electron transport complex
GPY22_RS01830	ENOG4105CSM	endonuclease III
GPY22_RS01835	ENOG4108UYE	Lactoylglutathione lyase
GPY22_RS01840	ENOG4106WH9	Protein of unknown function (DUF2753)
GPY22_RS01845	ENOG4105EIY	sodium-type flagellar protein motY
GPY22_RS01850	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GPY22_RS01855	ENOG4105D3Y	Na H antiporter
GPY22_RS01860	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GPY22_RS01865	ENOG4105E96	Colicin v production protein
GPY22_RS01870	ENOG4108S3P	Sporulation domain protein
GPY22_RS01875	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GPY22_RS01880	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GPY22_RS01885	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GPY22_RS01895	ENOG4105CX6	glutaminyL-tRNA synthetase
GPY22_RS01900	ENOG4105CI1	PTS System
GPY22_RS01905	ENOG4105CE4	GlcNAc 6-P deacetylase
GPY22_RS01910	ENOG4105E2R	ROK family
GPY22_RS01920	ENOG4105CAQ	asparagine synthetase
GPY22_RS01925	ENOG4105MDZ	Transcriptional activator rfaH
GPY22_RS01930	ENOG4105DUX	Transporter
GPY22_RS01935	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GPY22_RS01940	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GPY22_RS01945	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GPY22_RS01950	ENOG4108TU9	TRANSCRIPTIONal
GPY22_RS01965	ENOG4108RE9	Phosphodiesterase
GPY22_RS01990	ENOG4105ECP	epimerase
GPY22_RS01995	ENOG4105E1F	short-chain dehydrogenase reductase
GPY22_RS02005	ENOG4107QR8	Thioredoxin
GPY22_RS02010	ENOG4107QX8	SPFH domain, Band 7 family protein
GPY22_RS02020	ENOG4108Z6Z	Transcriptional regulator
GPY22_RS02035	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GPY22_RS02040	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GPY22_RS02045	ENOG4105EXN	Sulfate transport protein CysZ
GPY22_RS02050	ENOG4105C6T	cysteine synthase
GPY22_RS02060	ENOG4105KZ7	phosphocarrier protein hpr
GPY22_RS02070	ENOG4105C5Y	PTS System
GPY22_RS02075	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GPY22_RS02085	ENOG4105C9A	Phoh family
GPY22_RS02090	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GPY22_RS02095	ENOG4108JU5	Magnesium and cobalt efflux protein
GPY22_RS02100	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GPY22_RS02105	ENOG4107PAI	alpha helical protein
GPY22_RS02110	ENOG4105C8T	Leucyl-tRNA synthetase
GPY22_RS02115	ENOG4108U2H	Rare lipoprotein B
GPY22_RS02120	ENOG4105DJF	DNA polymerase III, delta' subunit
GPY22_RS02125	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GPY22_RS02130	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GPY22_RS02135	ENOG4105CJN	penicillin-binding protein
GPY22_RS02140	ENOG4105CNI	cell division protein FtsW
GPY22_RS02150	ENOG4105DZ1	carboxypeptidase
GPY22_RS02155	ENOG4108Z43	UPF0250 protein
GPY22_RS02165	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GPY22_RS02175	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GPY22_RS02190	ENOG410624X	efflux transporter, rnd family, mfp subunit
GPY22_RS02215	ENOG4105CG3	alpha amylase, catalytic region
GPY22_RS02220	ENOG4105C5Y	PTS System
GPY22_RS02235	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GPY22_RS02245	ENOG4108UMI	ABC transporter, permease
GPY22_RS02260	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
GPY22_RS02265	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GPY22_RS02275	ENOG4105BZU	Histidine kinase
GPY22_RS02280	ENOG4105EWT	decarboxylase family
GPY22_RS02285	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
GPY22_RS02290	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
GPY22_RS02295	ENOG4105M08	Membrane
GPY22_RS02305	ENOG4105ETT	transcriptional Regulator, LysR family
GPY22_RS02310	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GPY22_RS02315	ENOG4106VK6	Flagellar motor protein
GPY22_RS02320	ENOG4105E14	MotA TolQ exbB proton channel
GPY22_RS02325	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GPY22_RS02330	ENOG4105CTB	Polyprenyl synthetase
GPY22_RS02335	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GPY22_RS02340	ENOG4105DR9	pseudouridine synthase
GPY22_RS02345	ENOG4105WP7	tRNA pseudouridine synthase C
GPY22_RS02370	ENOG4108UPT	UPF0178 protein
GPY22_RS02375	ENOG4105CFC	Transporter
GPY22_RS02390	ENOG4108R96	Methyltransferase, YaeB family
GPY22_RS02395	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GPY22_RS02405	ENOG4105W1I	UPF0253 protein
GPY22_RS02415	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GPY22_RS02420	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GPY22_RS02425	ENOG4108Z6B	deaminase
GPY22_RS02430	ENOG4105CC0	LysR family Transcriptional regulator
GPY22_RS02435	ENOG4107QPD	alcohol dehydrogenase
GPY22_RS02440	ENOG4105C4W	S-formylglutathione hydrolase
GPY22_RS02445	ENOG4105CFC	Transporter
GPY22_RS02470	ENOG4108ZUW	Major pilin subunit
GPY22_RS02475	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GPY22_RS02480	ENOG4105CFG	Acts as a chaperone (By similarity)
GPY22_RS02495	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GPY22_RS02500	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GPY22_RS02505	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GPY22_RS02510	ENOG4105VDB	UPF0125 protein
GPY22_RS02515	ENOG4108Z1B	Cyclase dehydrase
GPY22_RS02520	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GPY22_RS02530	ENOG4105DFP	Integrase
GPY22_RS02590	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GPY22_RS02595	ENOG4105BZG	amino acid carrier protein
GPY22_RS02605	ENOG4105CH2	amidohydrolase
GPY22_RS02610	ENOG4105CSH	Transporter
GPY22_RS02615	ENOG4105C09	Bile acid
GPY22_RS02620	ENOG4106HK8	GPR1 FUN34 yaaH family protein
GPY22_RS02630	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GPY22_RS02635	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GPY22_RS02640	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GPY22_RS02655	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GPY22_RS02660	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GPY22_RS02665	ENOG4105N21	Membrane
GPY22_RS02680	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
GPY22_RS02690	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GPY22_RS02695	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GPY22_RS02700	ENOG4105WVQ	Fe-S assembly protein IscX
GPY22_RS02705	ENOG4108ZIT	Ferredoxin, 2FE-2S
GPY22_RS02710	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GPY22_RS02715	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
GPY22_RS02720	ENOG4108Z4V	iron-sulfur cluster assembly
GPY22_RS02725	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GPY22_RS02735	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GPY22_RS02740	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
GPY22_RS02745	ENOG4105ECY	inositol monophosphatase
GPY22_RS02755	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPY22_RS02760	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPY22_RS02765	ENOG4105VIE	preprotein translocase, subunit YajC
GPY22_RS02770	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GPY22_RS02775	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GPY22_RS02780	ENOG4105W87	Cbs domain
GPY22_RS02785	ENOG4108I9X	Isocitrate lyase
GPY22_RS02790	ENOG4107QP3	malate synthase g
GPY22_RS02800	ENOG4105D3R	alkyl hydroperoxide reductase
GPY22_RS02805	ENOG4106N3A	copper homeostasis protein cutc
GPY22_RS02810	ENOG4105CSR	polyphosphate kinase 2
GPY22_RS02820	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GPY22_RS02830	ENOG4105C8U	phosphate abc transporter
GPY22_RS02840	ENOG4105C9X	ppx gppa phosphatase
GPY22_RS02850	ENOG4105BZU	Histidine kinase
GPY22_RS02855	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GPY22_RS02860	ENOG4105DH7	May be involved in recombination (By similarity)
GPY22_RS02865	ENOG4105CFP	Peptidase U32
GPY22_RS02870	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GPY22_RS02885	ENOG4105K6V	RNA polymerase
GPY22_RS02895	ENOG4105DRB	nucleoside-specific channel-forming protein
GPY22_RS02900	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GPY22_RS02905	ENOG4107S0N	DJ-1 family
GPY22_RS02910	ENOG4105C9B	Cysteine desulfurase
GPY22_RS02920	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GPY22_RS02925	ENOG4105CUZ	uba thif-type nad fad binding protein
GPY22_RS02930	ENOG4105CA3	membrane-bound lytic murein transglycosylase
GPY22_RS02940	ENOG4107QZM	n-acetylglutamate synthase
GPY22_RS02955	ENOG4107QKA	exodeoxyribonuclease V beta
GPY22_RS02975	ENOG4105X2V	dna damage-inducible protein
GPY22_RS02980	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
GPY22_RS02985	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GPY22_RS03000	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY22_RS03015	ENOG4108Y51	tRNA-binding protein
GPY22_RS03020	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GPY22_RS03035	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GPY22_RS03135	ENOG4105ETT	transcriptional Regulator, LysR family
GPY22_RS03145	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GPY22_RS03155	ENOG4105EAC	phosphoserine phosphatase
GPY22_RS03170	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GPY22_RS03175	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GPY22_RS03180	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GPY22_RS03190	ENOG4105DIH	basic membrane
GPY22_RS03215	ENOG4105D1Q	UPF0246 protein
GPY22_RS03220	ENOG4105BZG	amino acid carrier protein
GPY22_RS03235	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GPY22_RS03240	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GPY22_RS03245	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
GPY22_RS03250	ENOG4105D98	threonine synthase
GPY22_RS03255	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GPY22_RS03270	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GPY22_RS03285	ENOG41065U4	response regulator
GPY22_RS03305	ENOG4105N5T	Radical SAM Protein
GPY22_RS03325	ENOG4105BZ8	glutamate synthase
GPY22_RS03335	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GPY22_RS03350	ENOG4105EN6	Membrane
GPY22_RS03370	ENOG4105VP0	transcriptional regulator, lysR family
GPY22_RS03375	ENOG4105EJ9	Membrane
GPY22_RS03380	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GPY22_RS03385	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GPY22_RS03390	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GPY22_RS03395	ENOG4105M6F	mutator MutT protein
GPY22_RS03400	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GPY22_RS03410	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPY22_RS03415	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GPY22_RS03420	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GPY22_RS03425	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GPY22_RS03430	ENOG4105DFU	Cell wall formation (By similarity)
GPY22_RS03435	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GPY22_RS03445	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GPY22_RS03455	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GPY22_RS03460	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GPY22_RS03465	ENOG4105CJN	penicillin-binding protein
GPY22_RS03470	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GPY22_RS03475	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GPY22_RS03485	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GPY22_RS03490	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
GPY22_RS03495	ENOG41082RQ	UPF0102 protein
GPY22_RS03500	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GPY22_RS03505	ENOG4105W4M	Transport-associated protein
GPY22_RS03510	ENOG4105KB2	stringent starvation protein b
GPY22_RS03515	ENOG4107MKT	Stringent starvation protein a
GPY22_RS03520	ENOG4105EIX	cytochrome c1
GPY22_RS03525	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GPY22_RS03535	ENOG4108UJD	30S ribosomal protein S9
GPY22_RS03540	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GPY22_RS03550	ENOG4105D6Z	AFG1 family ATPase
GPY22_RS03555	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
GPY22_RS03560	ENOG4105C0H	protease
GPY22_RS03565	ENOG4105C0H	protease
GPY22_RS03570	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GPY22_RS03580	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GPY22_RS03585	ENOG4105K5M	30s ribosomal protein S16
GPY22_RS03590	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPY22_RS03595	ENOG4106KVJ	cytochrome C assembly protein
GPY22_RS03600	ENOG4108JU6	CBS domain protein
GPY22_RS03605	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GPY22_RS03615	ENOG4105D9M	gamma-glutamylcysteine synthetase
GPY22_RS03625	ENOG4105W39	Membrane
GPY22_RS03630	ENOG4105CPQ	Dehydrogenase
GPY22_RS03635	ENOG4105D9Q	decarboxylase (Beta subunit)
GPY22_RS03640	ENOG4107QSA	Oxaloacetate decarboxylase
GPY22_RS03690	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GPY22_RS03695	ENOG4105CFH	Aspartokinase
GPY22_RS03700	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GPY22_RS03710	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GPY22_RS03715	ENOG4107TH8	cina domain protein
GPY22_RS03725	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPY22_RS03730	ENOG4108K5P	(LipO)protein
GPY22_RS03735	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GPY22_RS03740	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GPY22_RS03745	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
GPY22_RS03750	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GPY22_RS03755	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GPY22_RS03760	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GPY22_RS03765	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GPY22_RS03770	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY22_RS03775	ENOG4107ZVW	dihydroneopterin aldolase
GPY22_RS03780	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GPY22_RS03785	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
GPY22_RS03795	ENOG4105VCC	30S ribosomal protein S21
GPY22_RS03800	ENOG4105KTH	gatB Yqey
GPY22_RS03805	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GPY22_RS03810	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPY22_RS03830	ENOG4105D75	Capsular exopolysaccharide family
GPY22_RS03835	ENOG4105KJF	protein tyrosine phosphatase
GPY22_RS03855	ENOG4105CH5	extracellular solute-binding protein, family 7
GPY22_RS03865	ENOG410804X	Transcriptional regulator
GPY22_RS03875	ENOG4105BZU	Histidine kinase
GPY22_RS03890	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
GPY22_RS03900	ENOG4105D64	Mechanosensitive ion channel
GPY22_RS03905	ENOG4105D2N	Aldolase
GPY22_RS03910	ENOG4105BZA	Phosphoglycerate kinase
GPY22_RS03920	ENOG4105D05	Receptor
GPY22_RS03925	ENOG4108R4R	Iron-regulated virulence regulatory protein
GPY22_RS03930	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GPY22_RS03935	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GPY22_RS03945	ENOG4105GPY	SprT protein
GPY22_RS03950	ENOG4105RWS	endonuclease I
GPY22_RS03955	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GPY22_RS03960	ENOG4105D7Z	glutathione synthase
GPY22_RS03965	ENOG4108UJU	UPF0301 protein
GPY22_RS03970	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GPY22_RS03975	ENOG4105CZX	twitching motility protein
GPY22_RS03980	ENOG4105CZX	twitching motility protein
GPY22_RS03990	ENOG4105II7	pyrroline-5-carboxylate reductase
GPY22_RS03995	ENOG4108VIA	integral membrane protein
GPY22_RS04000	ENOG4105VZ9	UPF0235 protein
GPY22_RS04015	ENOG4105CSA	Coproporphyrinogen iii oxidase
GPY22_RS04025	ENOG4105CSV	Glutaminase
GPY22_RS04030	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GPY22_RS04035	ENOG4105CEN	a g-specific adenine glycosylase
GPY22_RS04040	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GPY22_RS04045	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
GPY22_RS04070	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY22_RS04100	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GPY22_RS04105	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GPY22_RS04110	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GPY22_RS04115	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GPY22_RS04120	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GPY22_RS04125	ENOG4105NWN	ApaG protein
GPY22_RS04130	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GPY22_RS04140	ENOG4107XM3	UPF0442 protein
GPY22_RS04145	ENOG4105DWK	Membrane
GPY22_RS04150	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPY22_RS04155	ENOG4105K46	50S ribosomal protein l27
GPY22_RS04160	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GPY22_RS04170	ENOG4105D5Q	Arginine ornithine antiporter
GPY22_RS04195	ENOG41081QV	Universal stress protein
GPY22_RS04215	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GPY22_RS04225	ENOG4105QD6	exported protein
GPY22_RS04230	ENOG4105C03	ribonuclease
GPY22_RS04235	ENOG4108Z03	MAF-like protein
GPY22_RS04240	ENOG4105VQ7	Rod shape-determining protein MreD
GPY22_RS04245	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GPY22_RS04250	ENOG4105DFF	Rod shape-determining protein mreb
GPY22_RS04285	ENOG4108VAU	general secretion pathway protein G
GPY22_RS04305	ENOG4107QHF	type ii secretion system protein e
GPY22_RS04340	ENOG41062P1	Diguanylate cyclase phosphodiesterase
GPY22_RS04345	ENOG4108UUM	single-stranded DNA-binding protein
GPY22_RS04350	ENOG41086KC	Transcriptional regulator
GPY22_RS04355	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GPY22_RS04370	ENOG4105C5R	Aminotransferase
GPY22_RS04375	ENOG4105CFH	Aspartokinase
GPY22_RS04380	ENOG4105C3R	Methionine synthase
GPY22_RS04385	ENOG4105EEQ	Na H antiporter
GPY22_RS04450	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GPY22_RS04455	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GPY22_RS04460	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GPY22_RS04480	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GPY22_RS04485	ENOG4105MYN	Zinc uptake regulation protein
GPY22_RS04495	ENOG4107QP8	phosphohexose isomerase
GPY22_RS04500	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GPY22_RS04505	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GPY22_RS04520	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GPY22_RS04525	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GPY22_RS04530	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
GPY22_RS04535	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GPY22_RS04540	ENOG4108UQY	Iron-storage protein
GPY22_RS04545	ENOG4105W53	bacterioferritin-associated ferredoxin
GPY22_RS04560	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GPY22_RS04565	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GPY22_RS04570	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GPY22_RS04575	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GPY22_RS04580	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
GPY22_RS04585	ENOG4105WWK	YheO domain protein
GPY22_RS04590	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GPY22_RS04600	ENOG41069P5	Protein slyX homolog
GPY22_RS04610	ENOG4105EPW	hflc protein
GPY22_RS04625	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GPY22_RS04640	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GPY22_RS04645	ENOG4105K8N	protein family UPF0079, ATPase
GPY22_RS04650	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GPY22_RS04700	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GPY22_RS04705	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GPY22_RS04710	ENOG4105DJ4	phosphatidylserine decarboxylase
GPY22_RS04715	ENOG4107QWE	)-transporter
GPY22_RS04730	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GPY22_RS04745	ENOG41062JF	Transcriptional regulator
GPY22_RS04755	ENOG4105E09	nadh pyrophosphatase
GPY22_RS04760	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
GPY22_RS04765	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GPY22_RS04775	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GPY22_RS04780	ENOG4108VZM	50s ribosomal protein L10
GPY22_RS04785	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GPY22_RS04795	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GPY22_RS04800	ENOG4105PM1	preprotein translocase subunit SecE
GPY22_RS04830	ENOG4105CS9	pantothenic acid kinase
GPY22_RS04835	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GPY22_RS04840	ENOG4105D4A	Cell wall formation (By similarity)
GPY22_RS04850	ENOG4105JIM	Phosphatidylserine synthase
GPY22_RS04905	ENOG4107QK7	reductase
GPY22_RS04915	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GPY22_RS04925	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GPY22_RS04930	ENOG4105K63	Thioredoxin
GPY22_RS04935	ENOG4105C1J	atp-dependent rna helicase
GPY22_RS04940	ENOG4105C9X	ppx gppa phosphatase
GPY22_RS04945	ENOG4105BZU	Histidine kinase
GPY22_RS04950	ENOG4105D8G	Major Facilitator superfamily
GPY22_RS04970	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GPY22_RS04975	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GPY22_RS04980	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GPY22_RS04985	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GPY22_RS04995	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
GPY22_RS05005	ENOG4105W1Y	Transcriptional regulator
GPY22_RS05015	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GPY22_RS05030	ENOG4105K70	DNA-binding protein
GPY22_RS05040	ENOG4105CUY	Mechanosensitive ion channel
GPY22_RS05045	ENOG4105R2J	Conserved Protein
GPY22_RS05050	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
GPY22_RS05055	ENOG4108RG0	uracil-dna glycosylase
GPY22_RS05060	ENOG4105CY0	Metallo-Beta-Lactamase
GPY22_RS05065	ENOG4105SFE	lipopolysaccharide biosynthesis protein
GPY22_RS05120	ENOG4105CAQ	asparagine synthetase
GPY22_RS05145	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
GPY22_RS05160	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GPY22_RS05170	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
GPY22_RS05180	ENOG4105XA0	heptosyltransferase ii
GPY22_RS05185	ENOG4105XA0	heptosyltransferase ii
GPY22_RS05190	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GPY22_RS05195	ENOG4107TAE	Glycosyl transferase (Group 1
GPY22_RS05200	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
GPY22_RS05205	ENOG4105DKP	glycosyl transferase, family 9
GPY22_RS05210	ENOG4106WTF	Glycosyl transferase, family 2
GPY22_RS05215	ENOG4105CPK	Glycosyl transferase (Group 1
GPY22_RS05220	ENOG4108PQP	glycosyl transferase group 1
GPY22_RS05225	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GPY22_RS05240	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GPY22_RS05250	ENOG4105W0E	50S ribosomal protein L33
GPY22_RS05255	ENOG4105KDC	50s ribosomal protein l28
GPY22_RS05265	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY22_RS05270	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GPY22_RS05280	ENOG4105D1S	lipid A biosynthesis
GPY22_RS05285	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GPY22_RS05290	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GPY22_RS05295	ENOG4105DSJ	YicC domain protein
GPY22_RS05310	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
GPY22_RS05315	ENOG4108HUF	Transporter
GPY22_RS05320	ENOG4105E0A	ABC, transporter
GPY22_RS05325	ENOG4105BZ1	(ABC) transporter
GPY22_RS05340	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GPY22_RS05345	ENOG4105FR1	rard protein
GPY22_RS05355	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
GPY22_RS05365	ENOG4105C4R	Atp-dependent dna helicase
GPY22_RS05395	ENOG4105DGW	oligopeptidase A
GPY22_RS05400	ENOG4105D6S	protein involved in catabolism of external DNA
GPY22_RS05405	ENOG4105DC8	reductase
GPY22_RS05410	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
GPY22_RS05420	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GPY22_RS05435	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPY22_RS05440	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GPY22_RS05445	ENOG4105DEF	Extracellular solute-binding protein, family 5
GPY22_RS05450	ENOG4108JQ6	ABC transporter
GPY22_RS05480	ENOG4105MPD	Cytochrome
GPY22_RS05485	ENOG4105C4R	Atp-dependent dna helicase
GPY22_RS05490	ENOG41067SE	Tetr family transcriptional regulator
GPY22_RS05495	ENOG410624X	efflux transporter, rnd family, mfp subunit
GPY22_RS05500	ENOG4105BZS	acriflavin resistance protein
GPY22_RS05510	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GPY22_RS05515	ENOG4105EMY	transcriptional regulator
GPY22_RS05560	ENOG4108Z0R	Transferase
GPY22_RS05565	ENOG4105SG3	Protein of unknown function (DUF1488)
GPY22_RS05570	ENOG4105E2X	shikimate dehydrogenase
GPY22_RS05575	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GPY22_RS05580	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GPY22_RS05590	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GPY22_RS05595	ENOG4108WI1	Dna topoisomerase
GPY22_RS05600	ENOG4108RPN	Protein smg homolog
GPY22_RS05605	ENOG4105C79	DNA protecting protein DprA
GPY22_RS05625	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GPY22_RS05630	ENOG4105C1A	potassium transporter peripheral membrane
GPY22_RS05635	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GPY22_RS05645	ENOG4108UT2	hemolysin iii
GPY22_RS05650	ENOG4108N23	SpoOM-related protein
GPY22_RS05660	ENOG4105PC1	Conserved Protein
GPY22_RS05670	ENOG4105E27	serine threonine protein kinase
GPY22_RS05675	ENOG4108Z33	Thiol disulfide Interchange Protein
GPY22_RS05680	ENOG4106HNH	Acyl-transferase
GPY22_RS05685	ENOG4105C0P	Mg chelatase subunit ChlI
GPY22_RS05695	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
GPY22_RS05700	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GPY22_RS05710	ENOG4105C7B	Threonine dehydratase
GPY22_RS05730	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GPY22_RS05745	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
GPY22_RS05750	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GPY22_RS05755	ENOG4105JKW	Valine--pyruvate aminotransferase
GPY22_RS05760	ENOG4108ZNX	Heat shock protein
GPY22_RS05765	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPY22_RS05770	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GPY22_RS05775	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GPY22_RS05780	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GPY22_RS05785	ENOG4105EAB	amino acid AbC transporter
GPY22_RS05790	ENOG4105E5Q	amino acid AbC transporter
GPY22_RS05805	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GPY22_RS05810	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GPY22_RS05815	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPY22_RS05820	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GPY22_RS05830	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GPY22_RS05835	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GPY22_RS05840	ENOG4107QJE	Chromosome Partitioning Protein
GPY22_RS05845	ENOG4105FA0	parb-like partition protein
GPY22_RS05850	ENOG410684E	atp synthase
GPY22_RS05855	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GPY22_RS05860	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GPY22_RS05865	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GPY22_RS05870	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GPY22_RS05875	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GPY22_RS05880	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GPY22_RS05885	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GPY22_RS05890	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GPY22_RS05895	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GPY22_RS05900	ENOG4105EAD	ABC transporter
GPY22_RS05910	ENOG4105CZQ	inner membrane transport protein YdhC
GPY22_RS05915	ENOG4105F52	Transcriptional regulator
GPY22_RS05920	ENOG4105CHU	acetyl-coa acetyltransferase
GPY22_RS05930	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GPY22_RS05940	ENOG4108RR8	protoporphyrinogen oxidase
GPY22_RS06005	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GPY22_RS06010	ENOG4105D06	uba thif-type nad fad binding protein
GPY22_RS06015	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GPY22_RS06020	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GPY22_RS06025	ENOG4105D41	biosynthesis protein thiH
GPY22_RS06030	ENOG4108IJ7	Glycine betaine
GPY22_RS06045	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
GPY22_RS06050	ENOG4105C26	Dehydrogenase
GPY22_RS06055	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
GPY22_RS06060	ENOG4105DC7	peptidase M24
GPY22_RS06060	ENOG4105DC7	peptidase M24
GPY22_RS06080	ENOG4108VVK	transcriptional Regulator, AsnC
GPY22_RS06100	ENOG4105EMK	carboxylate amino acid amine transporter
GPY22_RS06105	ENOG4108M6U	Universal stress protein A
GPY22_RS06110	ENOG41090A1	ferritin
GPY22_RS06115	ENOG4108V6B	universal stress protein B
GPY22_RS06120	ENOG4105CBX	hi0933 family
GPY22_RS06125	ENOG4105CNN	ABC, transporter
GPY22_RS06130	ENOG4105C2J	ABC transporter
GPY22_RS06135	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
GPY22_RS06140	ENOG4105EF1	ribulokinase
GPY22_RS06145	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
GPY22_RS06150	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
GPY22_RS06175	ENOG4105CGY	Dna recombination protein
GPY22_RS06180	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GPY22_RS06185	ENOG4105JC1	sterol-binding domain protein
GPY22_RS06190	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GPY22_RS06195	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GPY22_RS06200	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GPY22_RS06205	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GPY22_RS06215	ENOG4105D52	delta-aminolevulinic acid dehydratase
GPY22_RS06230	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GPY22_RS06235	ENOG4106RE7	Cytochrome
GPY22_RS06245	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
GPY22_RS06250	ENOG4105XCT	Protein of unknown function (DUF2489)
GPY22_RS06255	ENOG4105D4P	Coproporphyrinogen iii oxidase
GPY22_RS06265	ENOG4105ECF	c-methyltransferase
GPY22_RS06270	ENOG41076E6	Uroporphyrinogen-III Synthase
GPY22_RS06275	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GPY22_RS06280	ENOG4107T0K	Adenylate cyclase
GPY22_RS06285	ENOG4105XQ6	frataxin-like protein
GPY22_RS06295	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GPY22_RS06300	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GPY22_RS06305	ENOG4105CT0	Protein of unknown function, DUF484
GPY22_RS06310	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GPY22_RS06315	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
GPY22_RS06320	ENOG4105BZU	Histidine kinase
GPY22_RS06325	ENOG4106IUH	DTW domain containing protein
GPY22_RS06340	ENOG4105DQF	Hydrolase
GPY22_RS06350	ENOG410829K	Lysine exporter protein (Lyse ygga)
GPY22_RS06355	ENOG4105D58	Diguanylate phosphodiesterase
GPY22_RS06360	ENOG41082YX	Transcriptional regulator, arsr family
GPY22_RS06365	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GPY22_RS06380	ENOG4108RMU	ferritin dps family protein
GPY22_RS06410	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
GPY22_RS06420	ENOG4106H78	methyltransferase
GPY22_RS06430	ENOG4105CAK	Cell division ATP-binding protein ftsE
GPY22_RS06435	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GPY22_RS06440	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPY22_RS06445	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GPY22_RS06450	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
GPY22_RS06455	ENOG4105X6C	Flagellar basal body-associated protein FliL
GPY22_RS06460	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
GPY22_RS06465	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GPY22_RS06470	ENOG4105E55	glycerol-3-phosphate acyltransferase
GPY22_RS06475	ENOG41080IJ	Diacylglycerol kinase
GPY22_RS06490	ENOG4107R73	Mate efflux family protein
GPY22_RS06495	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
GPY22_RS06515	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GPY22_RS06525	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GPY22_RS06580	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GPY22_RS06585	ENOG4105BZU	Histidine kinase
GPY22_RS06590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY22_RS06605	ENOG4105C5F	glutamine synthetase
GPY22_RS06630	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GPY22_RS06635	ENOG4105SUU	thioesterase domain
GPY22_RS06640	ENOG4105JV1	AsmA family
GPY22_RS06645	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GPY22_RS06650	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GPY22_RS06655	ENOG4105VEJ	Heat shock protein
GPY22_RS06660	ENOG4108XKW	General secretion pathway protein C
GPY22_RS06670	ENOG4107QHF	type ii secretion system protein e
GPY22_RS06675	ENOG4105D7Q	type ii secretion system
GPY22_RS06680	ENOG4108VAU	general secretion pathway protein G
GPY22_RS06685	ENOG4105VWV	general secretion pathway protein h
GPY22_RS06690	ENOG4105X5Z	General secretion pathway protein I
GPY22_RS06695	ENOG4108WWZ	General secretion pathway protein J
GPY22_RS06700	ENOG4108RTD	type II secretion system protein K
GPY22_RS06710	ENOG4105U1E	general secretion pathway protein M
GPY22_RS06715	ENOG4105PIC	general secretion pathway protein N
GPY22_RS06725	ENOG4107RK2	ADP-ribose diphosphatase NudE
GPY22_RS06730	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
GPY22_RS06735	ENOG4105MJ2	Competence protein
GPY22_RS06740	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GPY22_RS06760	ENOG4108RRZ	Transcription elongation factor GreB
GPY22_RS06765	ENOG4105DIQ	Transcriptional regulator
GPY22_RS06770	ENOG4105C01	Dihydroxy-acid dehydratase
GPY22_RS06775	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GPY22_RS06780	ENOG4105C6Z	Gluconate
GPY22_RS06785	ENOG4108UHU	Aldolase
GPY22_RS06790	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GPY22_RS06795	ENOG4105E0F	Histidine kinase
GPY22_RS06800	ENOG4105C2W	permease
GPY22_RS06805	ENOG4105CB5	ATP-dependent DNA helicase recG
GPY22_RS06810	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
GPY22_RS06815	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GPY22_RS06820	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GPY22_RS06825	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GPY22_RS06835	ENOG4107QN1	sodium solute
GPY22_RS06845	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
GPY22_RS06855	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GPY22_RS06860	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GPY22_RS06865	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
GPY22_RS06870	ENOG4105CXT	aspartate transcarbamylase
GPY22_RS06875	ENOG4105DBV	ornithine carbamoyltransferase
GPY22_RS06880	ENOG4105C5B	carbamate kinase
GPY22_RS06885	ENOG4105CEU	Arginine dihydrolase
GPY22_RS06890	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
GPY22_RS06895	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GPY22_RS06900	ENOG4108IJ0	Aspartate ammonia-lyase
GPY22_RS06905	ENOG4105BZU	Histidine kinase
GPY22_RS06910	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
GPY22_RS06915	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GPY22_RS06920	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GPY22_RS06925	ENOG4105E0F	Histidine kinase
GPY22_RS06930	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GPY22_RS06940	ENOG41076HS	cation diffusion facilitator family transporter
GPY22_RS06945	ENOG4105CTQ	phosphohexokinase
GPY22_RS06950	ENOG4105CBT	Fructose-1,6-bisphosphatase
GPY22_RS06955	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
GPY22_RS06960	ENOG4105SYT	Methylenetetrahydrofolate reductase
GPY22_RS06965	ENOG4105CFH	Aspartokinase
GPY22_RS06970	ENOG4105C28	cystathionine
GPY22_RS06975	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
GPY22_RS06985	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GPY22_RS06990	ENOG4105C25	Primosomal protein n'
GPY22_RS06995	ENOG4105ETE	Transcriptional regulator (LacI family
GPY22_RS07005	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GPY22_RS07010	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GPY22_RS07015	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GPY22_RS07020	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GPY22_RS07030	ENOG4105CP7	Triose-phosphate isomerase
GPY22_RS07055	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GPY22_RS07060	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GPY22_RS07065	ENOG4105DKW	ABC transporter
GPY22_RS07075	ENOG4105KT7	mgtC SapB transporter
GPY22_RS07080	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GPY22_RS07085	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GPY22_RS07090	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GPY22_RS07095	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GPY22_RS07100	ENOG4105E33	succinate dehydrogenase
GPY22_RS07110	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
GPY22_RS07115	ENOG4107YZP	Rhodanese domain protein
GPY22_RS07120	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GPY22_RS07125	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GPY22_RS07130	ENOG4105D7W	serine acetyltransferase
GPY22_RS07135	ENOG4105U3E	Transcriptional regulator
GPY22_RS07140	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GPY22_RS07145	ENOG4105CWC	Acetylornithine deacetylase
GPY22_RS07150	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GPY22_RS07165	ENOG4105CH7	arginosuccinase
GPY22_RS07175	ENOG4105EHV	domain protein
GPY22_RS07180	ENOG4105C5Q	Transcriptional regulator
GPY22_RS07185	ENOG4108JQC	penicillin-binding protein 1A
GPY22_RS07210	ENOG4105E4G	Type IV pilus
GPY22_RS07215	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GPY22_RS07230	ENOG4105DFE	Dna adenine methylase
GPY22_RS07235	ENOG4105DJV	ribulose-phosphate 3-epimerase
GPY22_RS07240	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GPY22_RS07245	ENOG4105C31	Tryptophanyl-tRNA synthetase
GPY22_RS07260	ENOG4105DDQ	anthranilate synthase
GPY22_RS07265	ENOG4105C8Y	Acetylornithine aminotransferase
GPY22_RS07275	ENOG4105C26	Dehydrogenase
GPY22_RS07285	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GPY22_RS07290	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
GPY22_RS07300	ENOG4105DNZ	Alpha Beta Hydrolase
GPY22_RS07310	ENOG4105C5H	ABC transporter
GPY22_RS07315	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GPY22_RS07320	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GPY22_RS07325	ENOG4105VKU	nucleicacid-binding protein
GPY22_RS07330	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GPY22_RS07335	ENOG4105D44	asparaginase
GPY22_RS07340	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GPY22_RS07345	ENOG4108UV7	flagellar protein motX
GPY22_RS07350	ENOG4105E68	Sulfatase
GPY22_RS07355	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GPY22_RS07360	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GPY22_RS07365	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GPY22_RS07370	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GPY22_RS07375	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GPY22_RS07380	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GPY22_RS07385	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPY22_RS07390	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GPY22_RS07395	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GPY22_RS07400	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GPY22_RS07405	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GPY22_RS07410	ENOG41083MP	50s ribosomal protein l29
GPY22_RS07415	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GPY22_RS07420	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GPY22_RS07425	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GPY22_RS07430	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPY22_RS07435	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GPY22_RS07440	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GPY22_RS07445	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GPY22_RS07450	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GPY22_RS07455	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GPY22_RS07460	ENOG4105VPB	50S ribosomal protein L30
GPY22_RS07465	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GPY22_RS07470	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GPY22_RS07480	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPY22_RS07485	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GPY22_RS07490	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GPY22_RS07495	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GPY22_RS07500	ENOG4108ZT0	50S ribosomal protein l17
GPY22_RS07515	ENOG4105FHY	Opacity-associated protein A
GPY22_RS07525	ENOG4107YB6	acetyltransferase, (GNAT) family
GPY22_RS07530	ENOG4105C1J	atp-dependent rna helicase
GPY22_RS07545	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GPY22_RS07550	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GPY22_RS07555	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
GPY22_RS07560	ENOG4107QWE	)-transporter
GPY22_RS07565	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
GPY22_RS07585	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GPY22_RS07600	ENOG4108UUE	Transcriptional regulator
GPY22_RS07605	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GPY22_RS07620	ENOG41066HZ	AIG2-like family
GPY22_RS07625	ENOG4105F0N	pyrophosphate phospho-hydrolase
GPY22_RS07630	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GPY22_RS07635	ENOG4105DFU	Cell wall formation (By similarity)
GPY22_RS07640	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GPY22_RS07645	ENOG4105DP9	ABC transporter
GPY22_RS07650	ENOG4106SMU	thiamine transporter membrane protein
GPY22_RS07655	ENOG4107T0D	ABC, transporter
GPY22_RS07660	ENOG4105N42	UPF0307 protein
GPY22_RS07665	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GPY22_RS07675	ENOG41080Z8	PHOSPHOCARRIER protein
GPY22_RS07685	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GPY22_RS07690	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GPY22_RS07695	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPY22_RS07700	ENOG4108IUZ	ABC transporter
GPY22_RS07705	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
GPY22_RS07715	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
GPY22_RS07720	ENOG4105C2X	Arabinose 5-phosphate isomerase
GPY22_RS07735	ENOG4105CY3	ABC transporter, permease
GPY22_RS07740	ENOG4105E3I	toluene tolerance
GPY22_RS07745	ENOG4105UE2	Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane
GPY22_RS07750	ENOG4105VFK	BolA family
GPY22_RS07755	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GPY22_RS07760	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GPY22_RS07765	ENOG4105KME	endoribonuclease L-psp
GPY22_RS07770	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
GPY22_RS07775	ENOG4105CXT	aspartate transcarbamylase
GPY22_RS07780	ENOG4105DBV	ornithine carbamoyltransferase
GPY22_RS07785	ENOG4108IAB	Phoh family
GPY22_RS07805	ENOG4105D3G	Pseudouridine synthase
GPY22_RS07810	ENOG4105C5I	Dehydrogenase
GPY22_RS07815	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GPY22_RS07830	ENOG4108M8S	permease YjgP YjgQ family protein
GPY22_RS07835	ENOG4108K5H	permease YjgP YjgQ family protein
GPY22_RS07845	ENOG4105BZU	Histidine kinase
GPY22_RS07865	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
GPY22_RS07875	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GPY22_RS07920	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GPY22_RS07925	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GPY22_RS07930	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GPY22_RS07935	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GPY22_RS07955	ENOG41064T2	transcriptional regulator, lysR family
GPY22_RS07960	ENOG4108IQE	Amp-dependent synthetase and ligase
GPY22_RS07965	ENOG4105C7K	acetolactate synthase
GPY22_RS07970	ENOG4108ZP8	Acetolactate synthase small subunit
GPY22_RS07980	ENOG4105E66	phosphoriboisomerase A
GPY22_RS07985	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GPY22_RS07995	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GPY22_RS08005	ENOG4105D0A	hydroxylase
GPY22_RS08010	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GPY22_RS08025	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GPY22_RS08030	ENOG4105Y75	tpr repeat protein
GPY22_RS08040	ENOG4108IYU	L-aspartate oxidase
GPY22_RS08060	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
GPY22_RS08065	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GPY22_RS08070	ENOG4105C3F	Signal peptidase i
GPY22_RS08080	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GPY22_RS08085	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
GPY22_RS08090	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GPY22_RS08095	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GPY22_RS08105	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GPY22_RS08110	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GPY22_RS08115	ENOG4105DXN	mazG family
GPY22_RS08120	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GPY22_RS08130	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GPY22_RS08150	ENOG4105CJ3	phosphate transporter
GPY22_RS08155	ENOG4107IX6	phosphate transport regulator
GPY22_RS08165	ENOG4105EYW	Ion transport protein
GPY22_RS08170	ENOG4108NVR	Methyl-accepting chemotaxis
GPY22_RS08175	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GPY22_RS08180	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GPY22_RS08185	ENOG4105DFG	type I secretion outer membrane protein
GPY22_RS08190	ENOG41087AY	ADP-Ribose pyrophosphatase
GPY22_RS08195	ENOG4108SX3	cytoplasmic protein
GPY22_RS08200	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GPY22_RS08205	ENOG4105IPS	esterase
GPY22_RS08210	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPY22_RS08215	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPY22_RS08220	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
GPY22_RS08225	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
GPY22_RS08230	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GPY22_RS08235	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GPY22_RS08240	ENOG4105D7Q	type ii secretion system
GPY22_RS08250	ENOG4105X0D	Fimbrial protein
GPY22_RS08265	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
GPY22_RS08275	ENOG4105T95	Thiol disulfide interChange protein
GPY22_RS08280	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GPY22_RS08285	ENOG41073TP	transcriptional regulator
GPY22_RS08290	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GPY22_RS08310	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GPY22_RS08315	ENOG41077A9	carbonic anhydrase
GPY22_RS08320	ENOG4105DA5	(ABC) transporter
GPY22_RS08330	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GPY22_RS08335	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GPY22_RS08340	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY22_RS08345	ENOG4105DJ0	Poly(A) Polymerase
GPY22_RS08350	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GPY22_RS08355	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY22_RS08365	ENOG4105CQ7	ATP-dependent helicase
GPY22_RS08370	ENOG4105BZ4	penicillin-binding protein
GPY22_RS08375	ENOG4105D78	K07001 NTE family protein
GPY22_RS08385	ENOG4105XTV	UPF0231 protein
GPY22_RS08390	ENOG4108YZA	Nitrogen regulatory protein pii
GPY22_RS08425	ENOG4105E2D	ec 3.2.1.52
GPY22_RS08430	ENOG4105RD7	BadF BadG BcrA BcrD
GPY22_RS08440	ENOG4108JQ7	(ABC) transporter
GPY22_RS08450	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPY22_RS08470	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GPY22_RS08475	ENOG4105IPI	Membrane
GPY22_RS08480	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GPY22_RS08485	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GPY22_RS08505	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GPY22_RS08515	ENOG4105CJW	magnesium transporter
GPY22_RS08520	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GPY22_RS08525	ENOG4107QE9	Inherit from COG: Membrane
GPY22_RS08530	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GPY22_RS08540	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GPY22_RS08545	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GPY22_RS08550	ENOG4105EEI	dihydropteroate synthase
GPY22_RS08555	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GPY22_RS08575	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GPY22_RS08585	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GPY22_RS08590	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GPY22_RS08600	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GPY22_RS08605	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GPY22_RS08620	ENOG4105C3S	Mate efflux family protein
GPY22_RS08625	ENOG4106RZ4	Peptidase U32
GPY22_RS08630	ENOG4105CFP	Peptidase U32
GPY22_RS08635	ENOG4105BZU	Histidine kinase
GPY22_RS08645	ENOG4108YYD	acetyltransferase
GPY22_RS08655	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
GPY22_RS08660	ENOG4105BZU	Histidine kinase
GPY22_RS08665	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GPY22_RS08670	ENOG4105C1J	atp-dependent rna helicase
GPY22_RS08675	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GPY22_RS08695	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY22_RS08705	ENOG4105CPC	Aldo Keto reductase
GPY22_RS08715	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
GPY22_RS08720	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GPY22_RS08730	ENOG4105HF0	Membrane
GPY22_RS08735	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GPY22_RS08740	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GPY22_RS08750	ENOG41063Z6	transcriptional regulator, lysR family
GPY22_RS08755	ENOG41080HT	Transcriptional regulator, arsr family
GPY22_RS08760	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GPY22_RS08770	ENOG4105DTN	riboflavin biosynthesis protein ribF
GPY22_RS08780	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GPY22_RS08785	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GPY22_RS08790	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GPY22_RS08810	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPY22_RS08815	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GPY22_RS08825	ENOG4108NEV	two component transcriptional regulator, LytTR family
GPY22_RS08830	ENOG4108HRK	Histidine kinase
GPY22_RS08835	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GPY22_RS08850	ENOG4105C5H	ABC transporter
GPY22_RS08855	ENOG4107SC1	transglycosylase
GPY22_RS08870	ENOG4108K0B	C-di-gmp phosphodiesterase
GPY22_RS08875	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
GPY22_RS08885	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
GPY22_RS08890	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GPY22_RS08895	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY22_RS08900	ENOG4105C34	Pseudouridine synthase
GPY22_RS08905	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GPY22_RS08910	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GPY22_RS08920	ENOG4108Z6B	deaminase
GPY22_RS08925	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
GPY22_RS08995	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GPY22_RS09005	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GPY22_RS09015	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY22_RS09020	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY22_RS09025	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY22_RS09030	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY22_RS09035	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY22_RS09040	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
GPY22_RS09045	ENOG4105CJ2	(LipO)protein
GPY22_RS09060	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GPY22_RS09075	ENOG4105C8J	)-transporter
GPY22_RS09085	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY22_RS09090	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY22_RS09095	ENOG4105CIN	aminoacyl-histidine dipeptidase
GPY22_RS09100	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GPY22_RS09105	ENOG4108JPW	Aminotransferase
GPY22_RS09110	ENOG4105C26	Dehydrogenase
GPY22_RS09115	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
GPY22_RS09125	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPY22_RS09130	ENOG4105C7N	Xanthine uracil vitamin C permease
GPY22_RS09135	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GPY22_RS09150	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GPY22_RS09155	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GPY22_RS09160	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GPY22_RS09165	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GPY22_RS09180	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GPY22_RS09185	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GPY22_RS09190	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GPY22_RS09200	ENOG4108T8E	UPF0325 protein
GPY22_RS09210	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GPY22_RS09215	ENOG4105CE9	30S ribosomal protein S2
GPY22_RS09225	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GPY22_RS09230	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GPY22_RS09240	ENOG4105KNE	Phosphatidate cytidylyltransferase
GPY22_RS09245	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GPY22_RS09250	ENOG4105DZP	Membrane-associated zinc metalloprotease
GPY22_RS09255	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY22_RS09260	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
GPY22_RS09265	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPY22_RS09275	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPY22_RS09280	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPY22_RS09285	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GPY22_RS09290	ENOG4105C0B	DNA polymerase III (alpha subunit)
GPY22_RS09295	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GPY22_RS09300	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GPY22_RS09305	ENOG4105N7H	Cytochrome
GPY22_RS09310	ENOG4108YZA	Nitrogen regulatory protein pii
GPY22_RS09325	ENOG4105E9H	Lytic Murein transglycosylase
GPY22_RS09330	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GPY22_RS09335	ENOG4105D1A	Methyltransferase
GPY22_RS09340	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GPY22_RS09345	ENOG4107RZZ	dna polymerase iii epsilon subunit
GPY22_RS09360	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GPY22_RS09365	ENOG4105E7A	Glutamine amidotransferase
GPY22_RS09370	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GPY22_RS09385	ENOG4105FE9	pseudouridine synthase
GPY22_RS09390	ENOG4108DG9	Smr protein MutS2
GPY22_RS09420	ENOG4105C59	p-type ATPase
GPY22_RS09425	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GPY22_RS09430	ENOG4105UYK	outer membrane protein a
GPY22_RS09445	ENOG41080IJ	Diacylglycerol kinase
GPY22_RS09545	ENOG4105ED4	portal protein
GPY22_RS09585	ENOG4107R88	Chemotaxis protein (CheV)
GPY22_RS09590	ENOG4105BZU	Histidine kinase
GPY22_RS09595	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GPY22_RS09600	ENOG4108ZC9	flagellar basal-body rod protein flgc
GPY22_RS09605	ENOG4105W00	Flagellar hook capping protein
GPY22_RS09610	ENOG4105BZE	flagellar hook protein, FlgE
GPY22_RS09615	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GPY22_RS09620	ENOG4105CGA	flagellar basal-body rod protein FlgG
GPY22_RS09625	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GPY22_RS09635	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GPY22_RS09650	ENOG4105I03	Flagellin
GPY22_RS09655	ENOG4105I03	Flagellin
GPY22_RS09750	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GPY22_RS09755	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GPY22_RS09760	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GPY22_RS09765	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
GPY22_RS09770	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GPY22_RS09775	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GPY22_RS09780	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GPY22_RS09785	ENOG4108YY7	Invasion gene expression up-regulator SirB
GPY22_RS09790	ENOG41063JG	Transcriptional regulator
GPY22_RS09795	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GPY22_RS09800	ENOG4105CGH	5'-nucleotidase
GPY22_RS09805	ENOG4108Z66	YbaK ebsC protein
GPY22_RS09825	ENOG4105CS1	NAD(P)H quinone oxidoreductase
GPY22_RS09830	ENOG4105K89	arsenate reductase
GPY22_RS09850	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY22_RS09855	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPY22_RS09860	ENOG4105RH4	Glycine cleavage system transcriptional repressor
GPY22_RS09865	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GPY22_RS09870	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GPY22_RS09885	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GPY22_RS09890	ENOG4105KUZ	arsenate reductase
GPY22_RS09905	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GPY22_RS09910	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GPY22_RS09925	ENOG4105QZU	Inner membrane protein YfeZ
GPY22_RS09935	ENOG4105I03	Flagellin
GPY22_RS09940	ENOG4105I03	Flagellin
GPY22_RS09950	ENOG41063QE	flagellar protein FlaG
GPY22_RS09955	ENOG4107BRV	flagellar capping protein
GPY22_RS09965	ENOG4105MQ3	flagellar protein FliS
GPY22_RS09970	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY22_RS09975	ENOG4105BZU	Histidine kinase
GPY22_RS09980	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY22_RS09985	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GPY22_RS09990	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GPY22_RS09995	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GPY22_RS10030	ENOG4105DD5	Flagellar motor switch protein
GPY22_RS10035	ENOG4105VTB	flagellar biosynthesis protein fliO
GPY22_RS10040	ENOG4105CN7	Flagellar biosynthetic protein FliP
GPY22_RS10045	ENOG4105VS8	Flagellar biosynthetic protein fliq
GPY22_RS10050	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GPY22_RS10055	ENOG4105D00	flagellar biosynthetic protein flhB
GPY22_RS10070	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GPY22_RS10075	ENOG4105CBN	LysR family transcriptional regulator
GPY22_RS10080	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
GPY22_RS10085	ENOG4105EN6	Membrane
GPY22_RS10090	ENOG4108BPE	-transporting atpase
GPY22_RS10095	ENOG4105MH2	YfcL protein
GPY22_RS10110	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GPY22_RS10115	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GPY22_RS10125	ENOG41090R7	Ferric uptake
GPY22_RS10135	ENOG4105CMU	LysR family (Transcriptional regulator
GPY22_RS10145	ENOG41067MG	lrgb family
GPY22_RS10150	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GPY22_RS10160	ENOG4105EV9	Alpha Beta Hydrolase
GPY22_RS10165	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
GPY22_RS10170	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
GPY22_RS10180	ENOG4107QNR	UPF0135 protein
GPY22_RS10185	ENOG4105BZN	citrate synthase
GPY22_RS10190	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GPY22_RS10195	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GPY22_RS10200	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GPY22_RS10210	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GPY22_RS10215	ENOG4105C7S	Dehydrogenase
GPY22_RS10220	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GPY22_RS10225	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GPY22_RS10235	ENOG4105FDK	ABC transporter
GPY22_RS10240	ENOG4105NXV	High-affinity zinc uptake system protein
GPY22_RS10250	ENOG4105XFK	Ferrous iron transport protein A
GPY22_RS10270	ENOG4105C75	arginyL-tRNA synthetase
GPY22_RS10275	ENOG4106ZCM	YecM protein
GPY22_RS10280	ENOG4107QXK	peptidase
GPY22_RS10285	ENOG4108BY2	phosphohistidine phosphatase
GPY22_RS10295	ENOG4105FZW	flagellar biosynthesis regulator FlhF
GPY22_RS10300	ENOG4107R21	site-determining protein
GPY22_RS10305	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPY22_RS10310	ENOG4108VYJ	response regulator receiver protein
GPY22_RS10315	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
GPY22_RS10320	ENOG4105CBS	Chea signal transduction histidine kinase
GPY22_RS10325	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GPY22_RS10330	ENOG4107QJE	Chromosome Partitioning Protein
GPY22_RS10340	ENOG4108V3W	Chemotaxis protein, CheW
GPY22_RS10350	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
GPY22_RS10355	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
GPY22_RS10360	ENOG41060IM	Heme exporter protein
GPY22_RS10365	ENOG4105X3C	heme exporter protein
GPY22_RS10370	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
GPY22_RS10375	ENOG4105DA4	cytochrome c-type biogenesis protein
GPY22_RS10380	ENOG4107QX9	Thiol disulfide interChange protein
GPY22_RS10385	ENOG4108M1T	Cytochrome c-type biogenesis protein
GPY22_RS10390	ENOG4108M1T	Cytochrome c-type biogenesis protein
GPY22_RS10395	ENOG410903C	(LipO)protein
GPY22_RS10410	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GPY22_RS10415	ENOG4105M2J	Glutaredoxin
GPY22_RS10435	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPY22_RS10450	ENOG4105CPC	Aldo Keto reductase
GPY22_RS10465	ENOG4105DDW	LysR family Transcriptional regulator
GPY22_RS10470	ENOG4105KHM	amidohydrolase 2
GPY22_RS10475	ENOG4105JSC	dimethylmenaquinone methyltransferase
GPY22_RS10485	ENOG4105GAK	amidohydrolase 2
GPY22_RS10515	ENOG4105E2X	shikimate dehydrogenase
GPY22_RS10520	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GPY22_RS10530	ENOG4105DGU	Histone deacetylase
GPY22_RS10540	ENOG4105CGF	Aromatic amino acid aminotransferase
GPY22_RS10555	ENOG4105E68	Sulfatase
GPY22_RS10565	ENOG4106V8H	Nucleoid-associated protein
GPY22_RS10575	ENOG4105DFD	Na H antiporter
GPY22_RS10580	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GPY22_RS10585	ENOG4105EYW	Ion transport protein
GPY22_RS10590	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GPY22_RS10595	ENOG4108EKI	Dehydrogenase
GPY22_RS10605	ENOG4105CHH	sulfate transporter
GPY22_RS10620	ENOG4105EI2	Pseudouridine synthase
GPY22_RS10625	ENOG4108UHJ	MAF-like protein
GPY22_RS10630	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GPY22_RS10635	ENOG4105VGS	50s ribosomal protein l32
GPY22_RS10640	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GPY22_RS10650	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GPY22_RS10655	ENOG4105CHR	reductase
GPY22_RS10660	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GPY22_RS10665	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GPY22_RS10670	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
GPY22_RS10675	ENOG4105HHA	aminodeoxychorismate lyase
GPY22_RS10680	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GPY22_RS10685	ENOG4107QRG	dna polymerase iii
GPY22_RS10690	ENOG4105F8V	Hydrolase, tatD family
GPY22_RS10705	ENOG4105CI1	PTS System
GPY22_RS10720	ENOG4105C8J	)-transporter
GPY22_RS10735	ENOG4108NRW	Phospholipase, patatin family
GPY22_RS10745	ENOG4105DAG	ROK family
GPY22_RS10750	ENOG4107R88	Chemotaxis protein (CheV)
GPY22_RS10755	ENOG4105C0B	DNA polymerase III (alpha subunit)
GPY22_RS10770	ENOG4105UBK	short-chain dehydrogenase reductase
GPY22_RS10775	ENOG4105ERU	peptidase
GPY22_RS10790	ENOG4105C4K	Nad synthetase
GPY22_RS10810	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GPY22_RS10815	ENOG4105DK2	UPF0207 protein
GPY22_RS10820	ENOG4105CHM	Aminotransferase
GPY22_RS10825	ENOG4105E4F	Isochorismate synthase
GPY22_RS10830	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GPY22_RS10835	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
GPY22_RS10840	ENOG4108IPT	Naphthoate synthase
GPY22_RS10845	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
GPY22_RS10850	ENOG4105CEY	Amp-dependent synthetase and ligase
GPY22_RS10865	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
GPY22_RS10885	ENOG4105F4I	Transcriptional regulator
GPY22_RS10890	ENOG4105E9H	Lytic Murein transglycosylase
GPY22_RS10910	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GPY22_RS10915	ENOG4108ZC9	flagellar basal-body rod protein flgc
GPY22_RS10920	ENOG4105W00	Flagellar hook capping protein
GPY22_RS10925	ENOG4105BZE	flagellar hook protein, FlgE
GPY22_RS10930	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GPY22_RS10935	ENOG4105CGA	flagellar basal-body rod protein FlgG
GPY22_RS10940	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GPY22_RS10945	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GPY22_RS10950	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GPY22_RS10985	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
GPY22_RS10990	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GPY22_RS11000	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPY22_RS11035	ENOG4107S9F	NmrA family
GPY22_RS11050	ENOG4105ER2	Ompa motb domain protein
GPY22_RS11055	ENOG4107RD7	Flagellar Motor Protein, MotA
GPY22_RS11085	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
GPY22_RS11090	ENOG4105I03	Flagellin
GPY22_RS11105	ENOG4105D00	flagellar biosynthetic protein flhB
GPY22_RS11110	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GPY22_RS11115	ENOG4105VS8	Flagellar biosynthetic protein fliq
GPY22_RS11120	ENOG4105CN7	Flagellar biosynthetic protein FliP
GPY22_RS11125	ENOG4105DD5	Flagellar motor switch protein
GPY22_RS11135	ENOG41090EK	ompa motb domain protein
GPY22_RS11140	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY22_RS11150	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GPY22_RS11155	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GPY22_RS11165	ENOG4108JIR	Flagellum-specific ATP synthase
GPY22_RS11190	ENOG4105C29	acyl-CoA thioesterase
GPY22_RS11195	ENOG4108MNP	Glycoprotein polysaccharide metabolism
GPY22_RS11210	ENOG410620I	Diguanylate cyclase
GPY22_RS11250	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GPY22_RS11255	ENOG4108YYH	Nadph-dependent fmn reductase
GPY22_RS11260	ENOG4108KTG	Membrane protein, drug metabolite transporter
GPY22_RS11270	ENOG4105VEQ	Cold shock protein
GPY22_RS11295	ENOG4105R1U	AraC Family Transcriptional Regulator
GPY22_RS11305	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
GPY22_RS11310	ENOG4105DQU	oxidoreductase, subunit beta
GPY22_RS11315	ENOG4108V1U	phospholipid-binding protein
GPY22_RS11320	ENOG4108UQN	AraC family transcriptional regulator
GPY22_RS11340	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GPY22_RS11355	ENOG410624V	efflux system protein
GPY22_RS11370	ENOG4105DHQ	Histidine kinase
GPY22_RS11375	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GPY22_RS11380	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
GPY22_RS11390	ENOG4105C1J	atp-dependent rna helicase
GPY22_RS11395	ENOG4105E0M	Sulfatase
GPY22_RS11400	ENOG41080IJ	Diacylglycerol kinase
GPY22_RS11425	ENOG4108ZXC	Two component transcriptional regulator, luxr family
GPY22_RS11430	ENOG4106AFQ	Histidine kinase
GPY22_RS11435	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GPY22_RS11455	ENOG4105NQN	cytochrome C
GPY22_RS11465	ENOG4105BZU	Histidine kinase
GPY22_RS11480	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GPY22_RS11520	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GPY22_RS11525	ENOG4105F27	Major Facilitator
GPY22_RS11530	ENOG4105WQI	isochorismatase
GPY22_RS11540	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
GPY22_RS11545	ENOG4105E4F	Isochorismate synthase
GPY22_RS11550	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
GPY22_RS11575	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
GPY22_RS11580	ENOG4105DQ5	transport system permease protein
GPY22_RS11585	ENOG4105TVJ	transport system, permease
GPY22_RS11600	ENOG4105CEY	Amp-dependent synthetase and ligase
GPY22_RS11605	ENOG4105E0A	ABC, transporter
GPY22_RS11615	ENOG4105DDV	Transcriptional regulator (LacI family
GPY22_RS11620	ENOG4105CS2	ec 3.2.1.21
GPY22_RS11630	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GPY22_RS11635	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
GPY22_RS11640	ENOG4105DWF	phosphomethylpyrimidine kinase
GPY22_RS11645	ENOG4108JQ5	ABC transporter
GPY22_RS11650	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPY22_RS11655	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GPY22_RS11670	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GPY22_RS11675	ENOG4105CW7	secretion protein, HlyD family
GPY22_RS11685	ENOG4105UEI	Transcriptional Regulator AraC Family
GPY22_RS11695	ENOG4105ETX	regulatoR
GPY22_RS11705	ENOG4105C5Y	PTS System
GPY22_RS11720	ENOG4105BZU	Histidine kinase
GPY22_RS11745	ENOG4105C2D	reductase
GPY22_RS11755	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GPY22_RS11780	ENOG4105C84	Histidine ammonia-lyase
GPY22_RS11785	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
GPY22_RS11795	ENOG4105CEY	Amp-dependent synthetase and ligase
GPY22_RS11810	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GPY22_RS11815	ENOG4105CEY	Amp-dependent synthetase and ligase
GPY22_RS11845	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GPY22_RS11850	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPY22_RS11855	ENOG4105C3U	ABC transporter
GPY22_RS11860	ENOG4108JQ7	(ABC) transporter
GPY22_RS11870	ENOG4105CHF	Glutathione S-transferase
GPY22_RS11875	ENOG4107PU6	Membrane
GPY22_RS11880	ENOG4108DNC	Involved in acetate metabolism (By similarity)
GPY22_RS11885	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GPY22_RS11890	ENOG4105PQ6	UPF0208 membrane protein
GPY22_RS11900	ENOG4105C7J	ABC transporter, permease
GPY22_RS11905	ENOG4108JJB	ABC transporter
GPY22_RS11915	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
GPY22_RS11925	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GPY22_RS11935	ENOG4105D1H	recombination factor protein RarA
GPY22_RS11955	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GPY22_RS11975	ENOG4105DG7	nitrate ABC transporter
GPY22_RS11980	ENOG4105D7T	ABC transporter
GPY22_RS11995	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GPY22_RS12000	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GPY22_RS12010	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GPY22_RS12015	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GPY22_RS12020	ENOG4105D0M	Protease HtpX homolog
GPY22_RS12030	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GPY22_RS12045	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GPY22_RS12065	ENOG4107QTF	adenylosuccinate lyase
GPY22_RS12070	ENOG41075W9	High frequency lysogenization protein HflD homolog
GPY22_RS12075	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GPY22_RS12080	ENOG4107RE1	Inosine-guanosine kinase
GPY22_RS12095	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY22_RS12100	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GPY22_RS12105	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GPY22_RS12110	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GPY22_RS12115	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GPY22_RS12130	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GPY22_RS12135	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GPY22_RS12140	ENOG4108R99	pseudouridine synthase
GPY22_RS12150	ENOG4105VEQ	Cold shock protein
GPY22_RS12155	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GPY22_RS12160	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GPY22_RS12165	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GPY22_RS12170	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
GPY22_RS12175	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GPY22_RS12185	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GPY22_RS12190	ENOG4105RKX	Protein of unknown function (DUF2498)
GPY22_RS12200	ENOG4105BZU	Histidine kinase
GPY22_RS12205	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GPY22_RS12230	ENOG4105HP8	regulator of competence-specific genes
GPY22_RS12235	ENOG4105ETE	Transcriptional regulator (LacI family
GPY22_RS12240	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
GPY22_RS12245	ENOG4106WF9	DNA-binding transcriptional regulator TorR
GPY22_RS12250	ENOG4107S90	membrAne
GPY22_RS12255	ENOG4106371	Methyltransferase
GPY22_RS12260	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
GPY22_RS12270	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
GPY22_RS12275	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY22_RS12285	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY22_RS12290	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
GPY22_RS12305	ENOG4105C9M	aspartyl-trna synthetase
GPY22_RS12310	ENOG4107104	thymidine kinase
GPY22_RS12315	ENOG4105GFG	DUF218 domain
GPY22_RS12320	ENOG4108535	NAD dependent epimerase/dehydratase family
GPY22_RS12340	ENOG4105TMB	Formate nitrite transporter
GPY22_RS12360	ENOG4107QY8	reductase
GPY22_RS12395	ENOG4108JQ2	peptide transport system atp-binding protein
GPY22_RS12400	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
GPY22_RS12405	ENOG4108EU3	peptide transport system, permease
GPY22_RS12415	ENOG4108J59	Extracellular solute-binding protein, family 5
GPY22_RS12420	ENOG4105E51	psp operon transcriptional activator
GPY22_RS12425	ENOG41087YS	Phage shock protein A
GPY22_RS12430	ENOG4105YYT	phage shock protein B
GPY22_RS12435	ENOG4105FM1	phage shock protein C
GPY22_RS12440	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GPY22_RS12455	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GPY22_RS12475	ENOG4107QX9	Thiol disulfide interChange protein
GPY22_RS12485	ENOG4105C28	cystathionine
GPY22_RS12495	ENOG4105C8J	)-transporter
GPY22_RS12515	ENOG4108W1A	pseudouridine synthase
GPY22_RS12525	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GPY22_RS12530	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
GPY22_RS12535	ENOG4108VGW	abc transporter atp-binding protein
GPY22_RS12545	ENOG4105VNH	ABC transporter solute-binding protein
GPY22_RS12555	ENOG4105XZD	Fe-S protein
GPY22_RS12565	ENOG4107QWP	ABC-2 type transporter
GPY22_RS12570	ENOG4105CJ1	ABC, transporter
GPY22_RS12595	ENOG4105BZU	Histidine kinase
GPY22_RS12610	ENOG4105VEQ	Cold shock protein
GPY22_RS12645	ENOG4105EGS	Mechanosensitive ion channel
GPY22_RS12660	ENOG4105Y49	secretion protein, HlyD family
GPY22_RS12680	ENOG4105D5Q	Arginine ornithine antiporter
GPY22_RS12685	ENOG4105CXN	decarboxylase
GPY22_RS12690	ENOG4105CXN	decarboxylase
GPY22_RS12695	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
GPY22_RS12710	ENOG4105EQ2	LysR family Transcriptional regulator
GPY22_RS12715	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GPY22_RS12730	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GPY22_RS12735	ENOG4105EB3	Histidine kinase
GPY22_RS12740	ENOG4105ETX	regulatoR
GPY22_RS12755	ENOG4105I08	Pseudouridine synthase
GPY22_RS12760	ENOG4105C2C	drug resistance transporter, Bcr CflA
GPY22_RS12770	ENOG4105CGD	Nad-dependent epimerase dehydratase
GPY22_RS12775	ENOG4105UQX	Mate efflux family protein
GPY22_RS12780	ENOG4108I0Y	(ABC) transporter
GPY22_RS12795	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GPY22_RS12800	ENOG4105CDV	Ompa motb domain protein
GPY22_RS12830	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
GPY22_RS12835	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY22_RS12860	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GPY22_RS12865	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GPY22_RS12890	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GPY22_RS12895	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GPY22_RS12900	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GPY22_RS12905	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPY22_RS12940	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
GPY22_RS12945	ENOG4105EAQ	(twin-arginine translocation) pathway signal
GPY22_RS12950	ENOG4105C5X	domain protein
GPY22_RS12965	ENOG4105CH5	extracellular solute-binding protein, family 7
GPY22_RS12985	ENOG4105WH1	Two component transcriptional regulator luxr family
GPY22_RS12990	ENOG41067TZ	transcriptional regulator, MarR family
GPY22_RS12995	ENOG4105C94	Transporter
GPY22_RS13000	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY22_RS13005	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GPY22_RS13010	ENOG41080XP	Cbs domain
GPY22_RS13020	ENOG4105CGF	Aromatic amino acid aminotransferase
GPY22_RS13040	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY22_RS13045	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
GPY22_RS13050	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GPY22_RS13055	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GPY22_RS13065	ENOG4105EJQ	L-serine dehydratase
GPY22_RS13070	ENOG4105C44	Serine transporter
GPY22_RS13075	ENOG4105P8F	nudix hydrolase
GPY22_RS13090	ENOG4105CRQ	synthase (Component I)
GPY22_RS13105	ENOG4105CM6	amino acid regulated cytosolic protein
GPY22_RS13115	ENOG4108JU8	Transcriptional regulator
GPY22_RS13120	ENOG4105D9U	N-acetyltransferase
GPY22_RS13145	ENOG4105BZU	Histidine kinase
GPY22_RS13150	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY22_RS13155	ENOG4108PZW	LysR family Transcriptional regulator
GPY22_RS13160	ENOG41067V3	Antibiotic biosynthesis monooxygenase
GPY22_RS13165	ENOG4108RCM	Nitroreductase
GPY22_RS13180	ENOG4105CNT	hydrolase family 2
GPY22_RS13190	ENOG4105C2J	ABC transporter
GPY22_RS13230	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GPY22_RS13245	ENOG4105BZN	citrate synthase
GPY22_RS13250	ENOG4108I0Z	Aconitate hydratase
GPY22_RS13255	ENOG4105C7F	AcnD-accessory protein PrpF
GPY22_RS13260	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GPY22_RS13270	ENOG4105CW7	secretion protein, HlyD family
GPY22_RS13275	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GPY22_RS13290	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GPY22_RS13295	ENOG4107XTP	(EAL) domain protein
GPY22_RS13300	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GPY22_RS13305	ENOG4105F1J	Homogentisate 1,2-dioxygenase
GPY22_RS13315	ENOG4108RXX	maleylacetoacetate isomerase
GPY22_RS13335	ENOG4105XEP	YhcH YjgK YiaL family protein
GPY22_RS13340	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
GPY22_RS13345	ENOG4105E98	transcriptional regulator DeoR family
GPY22_RS13350	ENOG4108IJ9	(ABC) transporter
GPY22_RS13355	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
GPY22_RS13370	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GPY22_RS13380	ENOG4105QNF	Outer membrane lipoprotein
GPY22_RS13400	ENOG4109015	Biopolymer transport protein exbD tolR
GPY22_RS13420	ENOG4108NRW	Phospholipase, patatin family
GPY22_RS13435	ENOG4107QI1	Mate efflux family protein
GPY22_RS13440	ENOG4108R6K	riboflavin synthase, subunit alpha
GPY22_RS13450	ENOG4105FGM	Fructosamine kinase
GPY22_RS13460	ENOG4107TT5	NLP P60 protein
GPY22_RS13465	ENOG4108N3W	hemolysin secretion protein
GPY22_RS13475	ENOG4106IUH	DTW domain containing protein
GPY22_RS13480	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
GPY22_RS13490	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GPY22_RS13495	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GPY22_RS13500	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPY22_RS13505	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
GPY22_RS13515	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY22_RS13535	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GPY22_RS13555	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
GPY22_RS13570	ENOG4105QAX	Iron-sulfur
GPY22_RS13590	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GPY22_RS13600	ENOG4107RUE	extracellular solute-binding protein family 1
GPY22_RS13605	ENOG4105D38	putrescine abc transporter
GPY22_RS13610	ENOG4105F38	ABC transporter, permease
GPY22_RS13615	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPY22_RS13635	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GPY22_RS13640	ENOG4105Q9Y	Universal stress protein
GPY22_RS13645	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GPY22_RS13660	ENOG4105C59	p-type ATPase
GPY22_RS13670	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
GPY22_RS13685	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
GPY22_RS13700	ENOG4105BZU	Histidine kinase
GPY22_RS13720	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
GPY22_RS13730	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
GPY22_RS13745	ENOG4105C5H	ABC transporter
GPY22_RS13755	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GPY22_RS13760	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
GPY22_RS13765	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GPY22_RS13770	ENOG4105C7I	Dehydrogenase
GPY22_RS13795	ENOG4105CN1	protease
GPY22_RS13800	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
GPY22_RS13805	ENOG4108ZGC	gaf domain protein
GPY22_RS13810	ENOG4105BZ1	(ABC) transporter
GPY22_RS13815	ENOG4105H2K	paraquat-inducible protein a
GPY22_RS13820	ENOG4105DY2	Paraquat-inducible protein b
GPY22_RS13825	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GPY22_RS13830	ENOG4105QNR	S1 RNA binding domain protein
GPY22_RS13850	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GPY22_RS13875	ENOG4105BZG	amino acid carrier protein
GPY22_RS13900	ENOG4105CS6	Rhs element vgr protein
GPY22_RS13905	ENOG4108WC9	type VI secretion system effector, hcp1 family
GPY22_RS13920	ENOG4105CQ7	ATP-dependent helicase
GPY22_RS13935	ENOG4105CUW	cytochrome C-TYPE protein
GPY22_RS13970	ENOG4105CFG	Acts as a chaperone (By similarity)
GPY22_RS13990	ENOG4105BZU	Histidine kinase
GPY22_RS14005	ENOG4105E9S	glutaredoxin 2
GPY22_RS14025	ENOG4105BZU	Histidine kinase
GPY22_RS14035	ENOG4107QY8	reductase
GPY22_RS14050	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GPY22_RS14055	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GPY22_RS14060	ENOG410667J	hydrolase
GPY22_RS14075	ENOG4105EZ7	amino acid ABC transporter
GPY22_RS14080	ENOG4105DRP	amino acid AbC transporter
GPY22_RS14085	ENOG4105CDA	abc transporter atp-binding protein
GPY22_RS14090	ENOG4108MN8	Membrane
GPY22_RS14095	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GPY22_RS14105	ENOG4105DR4	Methyltransferase
GPY22_RS14150	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
GPY22_RS14160	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GPY22_RS14195	ENOG4107SDU	Methyl-accepting chemotaxis
GPY22_RS14210	ENOG4105VEQ	Cold shock protein
GPY22_RS14250	ENOG4106H3A	restriction
GPY22_RS14460	ENOG4105TKZ	Tail Sheath
GPY22_RS14500	ENOG4105BZU	Histidine kinase
GPY22_RS14515	ENOG4107R88	Chemotaxis protein (CheV)
GPY22_RS14525	ENOG4106YYS	transcriptional regulatory protein
GPY22_RS14545	ENOG4107V40	secretion protein, HlyD family
GPY22_RS14565	ENOG4105CVG	Homoserine O-transsuccinylase
GPY22_RS14570	ENOG41090FY	type IV pilus biogenesis stability protein PilW
GPY22_RS14595	ENOG4105F04	LysR family Transcriptional regulator
GPY22_RS14645	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
GPY22_RS14650	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
GPY22_RS14665	ENOG4108YZT	Adenosylcobinamide kinase
GPY22_RS14670	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
GPY22_RS14680	ENOG4107XWI	flavin reductase domain protein, FMN-binding
GPY22_RS14690	ENOG4108ETY	sodium dicarboxylate symporter
GPY22_RS14700	ENOG4105CJB	Exodeoxyribonuclease I
GPY22_RS14715	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
GPY22_RS14745	ENOG4107SDU	Methyl-accepting chemotaxis
GPY22_RS14750	ENOG4105FQ6	thiopurine methyltransferase
GPY22_RS14760	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GPY22_RS14825	ENOG4105WH1	Two component transcriptional regulator luxr family
GPY22_RS14845	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GPY22_RS14855	ENOG41060QA	UPF0267 protein
GPY22_RS14870	ENOG41088SP	formiminoglutamate hydrolase
GPY22_RS14875	ENOG4105CGP	Urocanate hydratase
GPY22_RS14900	ENOG4105CQB	FAD linked oxidase domain protein
GPY22_RS14915	ENOG4108ZG0	Ompa motb domain protein
GPY22_RS14940	ENOG4108JPW	Aminotransferase
GPY22_RS14945	ENOG4105C26	Dehydrogenase
GPY22_RS14950	ENOG4105DWY	Agmatine deiminase
GPY22_RS14960	ENOG4105CJP	fad dependent oxidoreductase
GPY22_RS14965	ENOG4105C26	Dehydrogenase
GPY22_RS14975	ENOG4105VEQ	Cold shock protein
GPY22_RS15010	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GPY22_RS15015	ENOG4105C5I	Dehydrogenase
GPY22_RS15030	ENOG4108JUA	Transcriptional regulator
GPY22_RS15105	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
GPY22_RS15135	ENOG4105D6J	arsenicaL-resistance protein
GPY22_RS15215	ENOG4105KME	endoribonuclease L-psp
GPY22_RS15240	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY22_RS15255	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
GPY22_RS15260	ENOG4105C5I	Dehydrogenase
GPY22_RS15265	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
GPY22_RS15270	ENOG4105C6Z	Gluconate
GPY22_RS15275	ENOG4105BZW	Glycerate kinase
GPY22_RS15280	ENOG4105CFC	Transporter
GPY22_RS15285	ENOG4105CH2	amidohydrolase
GPY22_RS15300	ENOG4105D5Q	Arginine ornithine antiporter
GPY22_RS15320	ENOG4105CC0	LysR family Transcriptional regulator
GPY22_RS15335	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GPY22_RS15340	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
GPY22_RS15345	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GPY22_RS15360	ENOG4107SSZ	Phosphatase
GPY22_RS15380	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
GPY22_RS15385	ENOG4105EXG	Transcriptional regulator
GPY22_RS15395	ENOG4105C26	Dehydrogenase
GPY22_RS15400	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GPY22_RS15405	ENOG4105CPQ	Dehydrogenase
GPY22_RS15425	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GPY22_RS15460	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GPY22_RS15465	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GPY22_RS15475	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GPY22_RS15500	ENOG4105IHM	Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity)
GPY22_RS15505	ENOG41066DG	(EAL) domain protein
GPY22_RS15515	ENOG4105BZ1	(ABC) transporter
GPY22_RS15520	ENOG4105BZ1	(ABC) transporter
GPY22_RS15530	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
GPY22_RS15535	ENOG4107RSM	transcriptional regulator
GPY22_RS15545	ENOG4105KME	endoribonuclease L-psp
GPY22_RS15555	ENOG4106943	Heat shock protein
GPY22_RS15560	ENOG4105EIF	outer membrane protein W
GPY22_RS15565	ENOG4105D4Y	metalloprotease
GPY22_RS15585	ENOG4107RGM	aldo keto reductase
GPY22_RS15590	ENOG4108HRK	Histidine kinase
GPY22_RS15595	ENOG4108VAC	response regulator
GPY22_RS15600	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GPY22_RS15605	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
GPY22_RS15650	ENOG4108XM1	transcriptional regulator AsnC family
GPY22_RS15655	ENOG4108NVR	Methyl-accepting chemotaxis
GPY22_RS15660	ENOG4107IFA	Lipase (EC 3.1.1.3)
GPY22_RS15670	ENOG4107G87	m6 family metalloprotease domain protein
GPY22_RS15690	ENOG4105DHS	permease protein
GPY22_RS15700	ENOG4108IPW	abc transporter atp-binding protein
GPY22_RS15705	ENOG4105T16	Transcriptional regulator (AraC family)
GPY22_RS15720	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GPY22_RS15745	ENOG4105CVJ	phosphoglycerate mutase
GPY22_RS15760	ENOG4105DHT	Metal Dependent Phosphohydrolase
GPY22_RS15765	ENOG4105C0A	alcohol dehydrogenase
GPY22_RS15770	ENOG4105T16	Transcriptional regulator (AraC family)
GPY22_RS15795	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
GPY22_RS15800	ENOG4108JU3	Alkyl hydroperoxide reductase
GPY22_RS15805	ENOG4105D3R	alkyl hydroperoxide reductase
GPY22_RS15815	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
GPY22_RS15820	ENOG4108IPT	Naphthoate synthase
GPY22_RS15825	ENOG4107QX3	carboxylase
GPY22_RS15830	ENOG4105C1G	acyl-Coa dehydrogenase
GPY22_RS15840	ENOG4105CHU	acetyl-coa acetyltransferase
GPY22_RS15845	ENOG4105C26	Dehydrogenase
GPY22_RS15855	ENOG4105E39	Enoyl-CoA hydratase
GPY22_RS15860	ENOG4105E39	Enoyl-CoA hydratase
GPY22_RS15865	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GPY22_RS15870	ENOG4105CHR	reductase
GPY22_RS15875	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
GPY22_RS15880	ENOG4105CHR	reductase
GPY22_RS15885	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GPY22_RS15890	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPY22_RS15900	ENOG4105CH5	extracellular solute-binding protein, family 7
GPY22_RS15925	ENOG4105D01	(LipO)protein
GPY22_RS15945	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
GPY22_RS15950	ENOG4105C8U	phosphate abc transporter
GPY22_RS15955	ENOG4105E2Z	phosphate ABC transporter (Permease
GPY22_RS15960	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GPY22_RS15970	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
GPY22_RS15980	ENOG4105CYM	Glutathione S-transferase
GPY22_RS15990	ENOG4105BZJ	Electron transfer flavoprotein
GPY22_RS15995	ENOG4105C10	Electron transfer flavoprotein
GPY22_RS16005	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GPY22_RS16020	ENOG4108KMV	Glycosyl transferase (Group 1
GPY22_RS16035	ENOG4108UW5	maltose o-acetyltransferase
GPY22_RS16060	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY22_RS16065	ENOG4105BZU	Histidine kinase
GPY22_RS16130	ENOG4105CTX	dehydratase
GPY22_RS16140	ENOG4105D2H	Uronic isomerase
GPY22_RS16150	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPY22_RS16155	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GPY22_RS16165	ENOG4105EHG	Permease protein
GPY22_RS16170	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GPY22_RS16180	ENOG4108MGI	Transcriptional regulator
GPY22_RS16200	ENOG4108NIW	Leucine export protein LeuE
GPY22_RS16215	ENOG4105CC0	LysR family Transcriptional regulator
GPY22_RS16230	ENOG4105CIF	Ornithine Cyclodeaminase
GPY22_RS16235	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPY22_RS16245	ENOG4105CH5	extracellular solute-binding protein, family 7
GPY22_RS16250	ENOG4105II7	pyrroline-5-carboxylate reductase
GPY22_RS16265	ENOG4105ETT	transcriptional Regulator, LysR family
GPY22_RS16275	ENOG4105QVC	MOSC domain-containing protein
GPY22_RS16325	ENOG4105BZU	Histidine kinase
GPY22_RS16330	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GPY22_RS16345	ENOG4105DEF	Extracellular solute-binding protein, family 5
GPY22_RS16355	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPY22_RS16365	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GPY22_RS16380	ENOG4105BZU	Histidine kinase
GPY22_RS16385	ENOG4108UW5	maltose o-acetyltransferase
GPY22_RS16390	ENOG4105E98	transcriptional regulator DeoR family
GPY22_RS16395	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GPY22_RS16410	ENOG4105DM4	PTS System
GPY22_RS16415	ENOG4105EIP	mannose-6-phosphate isomerase
GPY22_RS16420	ENOG4105DM4	PTS System
GPY22_RS16425	ENOG4106R3P	AraC family transcriptional regulator
GPY22_RS16435	ENOG4108YRF	PTS System
GPY22_RS16460	ENOG4105SB3	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
GPY22_RS16465	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPY22_RS16475	ENOG4108TU9	TRANSCRIPTIONal
GPY22_RS16540	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
GPY22_RS16550	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GPY22_RS16575	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
GPY22_RS16580	ENOG4105C1J	atp-dependent rna helicase
GPY22_RS16585	ENOG4105C22	threonyL-tRNA synthetase
GPY22_RS16590	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GPY22_RS16595	ENOG41082NX	50s ribosomal protein l35
GPY22_RS16600	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GPY22_RS16625	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GPY22_RS16635	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
GPY22_RS16690	ENOG4105VUF	Transcriptional regulator
GPY22_RS16695	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
GPY22_RS16705	ENOG4108594	Permease of the drug metabolite transporter
GPY22_RS16720	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
GPY22_RS16755	ENOG4105I4A	GCN5-related N-acetyltransferase
GPY22_RS16765	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GPY22_RS16785	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
GPY22_RS16800	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
GPY22_RS16815	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GPY22_RS16825	ENOG4105M6F	mutator MutT protein
GPY22_RS16840	ENOG4105KD7	acetyltransferase
GPY22_RS16850	ENOG4108RWI	nicotinamidase
GPY22_RS16865	ENOG4108VP3	Lysine exporter protein (LysE YggA)
GPY22_RS16880	ENOG4108M3J	Dehydrogenase
GPY22_RS16885	ENOG4105J7D	transcriptional regulator
GPY22_RS16900	ENOG4108WAV	Transcriptional regulator
GPY22_RS16910	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GPY22_RS16920	ENOG4108KXV	response regulator
GPY22_RS16925	ENOG4105N14	lysine exporter protein LysE YggA
GPY22_RS16980	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GPY22_RS16985	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
GPY22_RS16990	ENOG4105CGF	Aromatic amino acid aminotransferase
GPY22_RS16995	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY22_RS17000	ENOG4105DM4	PTS System
GPY22_RS17005	ENOG4105DE4	1-phosphofructokinase
GPY22_RS17015	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
GPY22_RS17025	ENOG4105EYH	Exonuclease
GPY22_RS17030	ENOG4108MGY	Histidine kinase
GPY22_RS17035	ENOG4107KBT	8-Amino-7-oxononanoate synthase
GPY22_RS17045	ENOG4105CMQ	Chloride channel
GPY22_RS17050	ENOG4105CKI	cobalamin synthesis protein
GPY22_RS17060	ENOG4105R1U	AraC Family Transcriptional Regulator
GPY22_RS17070	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GPY22_RS17090	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GPY22_RS17130	ENOG4105DS1	cytochrome b561
GPY22_RS17135	ENOG4108YYC	ycei family
GPY22_RS17140	ENOG4105TMB	Formate nitrite transporter
GPY22_RS17150	ENOG4108UQ5	membrane protein YcdZ
GPY22_RS17155	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
GPY22_RS17160	ENOG4105CGH	5'-nucleotidase
GPY22_RS17180	ENOG4105D0M	Protease HtpX homolog
GPY22_RS17185	ENOG4105KA0	thioesterase Superfamily protein
GPY22_RS17210	ENOG4105CWB	LysR family transcriptional Regulator
GPY22_RS17215	ENOG4105CD5	CoA-binding domain protein
GPY22_RS17225	ENOG4105CPF	Cell wall formation (By similarity)
GPY22_RS17240	ENOG4108ZJT	translation initiation factor, Sui1
GPY22_RS17260	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
GPY22_RS17275	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GPY22_RS17300	ENOG4105BZU	Histidine kinase
GPY22_RS17310	ENOG4108R86	Transcriptional regulator
GPY22_RS17315	ENOG4105C2J	ABC transporter
GPY22_RS17320	ENOG4105UIB	(ABC) transporter
GPY22_RS17355	ENOG4105VT2	5-hydroxyisourate hydrolase
GPY22_RS17380	ENOG4105C5R	Aminotransferase
GPY22_RS17385	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GPY22_RS17395	ENOG4105DHU	Bile acid
GPY22_RS17410	ENOG4105E5Q	amino acid AbC transporter
GPY22_RS17435	ENOG410633P	Hydantoin racemase
GPY22_RS17445	ENOG4105C2W	permease
GPY22_RS17450	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GPY22_RS17460	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GPY22_RS17490	ENOG4108TU9	TRANSCRIPTIONal
GPY22_RS17495	ENOG4105ENX	hydrolase
GPY22_RS17520	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPY22_RS17525	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
GPY22_RS17530	ENOG4105C5H	ABC transporter
GPY22_RS17540	ENOG4105C87	Aminotransferase class I and II
GPY22_RS17560	ENOG4105CF7	AraC family transcriptional regulator
GPY22_RS17565	ENOG4107QW4	alcohol dehydrogenase
GPY22_RS17625	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GPY22_RS17630	ENOG4105WQ3	Rna-binding protein
GPY22_RS17645	ENOG4105BZU	Histidine kinase
GPY22_RS17650	ENOG4108Q9V	regulatoR
GPY22_RS17670	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GPY22_RS17675	ENOG4108JQ5	ABC transporter
GPY22_RS17680	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
GPY22_RS17685	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
GPY22_RS17690	ENOG4105E43	Extracellular solute-binding protein, family 5
GPY22_RS17730	ENOG4107RCV	ABC transporter, permease
GPY22_RS17750	ENOG4108JPW	Aminotransferase
GPY22_RS17755	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
GPY22_RS17765	ENOG4105NXH	GreA GreB family elongation factor
GPY22_RS17770	ENOG4105PAD	Hydrolase
GPY22_RS17775	ENOG4105JQN	Transcriptional regulator
GPY22_RS17780	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
GPY22_RS17785	ENOG4105CKU	formyltetrahydrofolate synthetase
GPY22_RS17800	ENOG4105CPD	ethanolamine ammonia-lyase
GPY22_RS17810	ENOG4105CUB	amino acid
GPY22_RS17830	ENOG4105KHC	sulfurtransferase
GPY22_RS17840	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GPY22_RS17845	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GPY22_RS17850	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GPY22_RS17855	ENOG4105CDV	Ompa motb domain protein
GPY22_RS17865	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GPY22_RS17870	ENOG4107VXZ	Hydrolase
GPY22_RS17875	ENOG4108N3W	hemolysin secretion protein
GPY22_RS17880	ENOG4105DXI	Major Facilitator superfamily
GPY22_RS17895	ENOG4105CEE	C4-dicarboxylate transporter
GPY22_RS17900	ENOG4105WH1	Two component transcriptional regulator luxr family
GPY22_RS17920	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GPY22_RS17960	ENOG4105CHU	acetyl-coa acetyltransferase
GPY22_RS17970	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPY22_RS17975	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPY22_RS17995	ENOG4105BZU	Histidine kinase
GPY22_RS18015	ENOG4105CF7	AraC family transcriptional regulator
GPY22_RS18020	ENOG4108I6A	alcohol dehydrogenase
GPY22_RS18030	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
GPY22_RS18050	ENOG4105CA9	Pyruvate kinase
GPY22_RS18055	ENOG4105BZU	Histidine kinase
GPY22_RS18060	ENOG4108SV3	Tmao reductase system periplasmic protein tort
GPY22_RS18065	ENOG4108Z5K	methylglyoxal synthase
GPY22_RS18070	ENOG4108RWI	nicotinamidase
GPY22_RS18100	ENOG4105CDV	Ompa motb domain protein
GPY22_RS18120	ENOG4108JJA	ABC, transporter
GPY22_RS18125	ENOG4105EM2	membrane
GPY22_RS18140	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GPY22_RS18145	ENOG4105E0C	molybdate abc transporter
GPY22_RS18150	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GPY22_RS18155	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GPY22_RS18175	ENOG4105BZU	Histidine kinase
GPY22_RS18180	ENOG4108QGH	periplasmic
GPY22_RS18190	ENOG41082IR	Excinuclease ABC C subunit domain protein
GPY22_RS18205	ENOG41090HJ	UPF0265 protein
GPY22_RS18230	ENOG4106CC8	Bacterial inner membrane protein
GPY22_RS18235	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GPY22_RS18240	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GPY22_RS18245	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
GPY22_RS18250	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
GPY22_RS18260	ENOG4105C4C	beta-galactosidase
GPY22_RS18270	ENOG4107RA4	Glycosyl transferase (Group 1
GPY22_RS18275	ENOG4105CG5	Glycosyl transferase (Group 1
GPY22_RS18300	ENOG4105DAY	polysaccharide export protein
GPY22_RS18310	ENOG4105D3Q	Sugar transferase
GPY22_RS18325	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GPY22_RS18330	ENOG4105K63	Thioredoxin
GPY22_RS18340	ENOG4105VXR	cytoplasmic protein
GPY22_RS18370	ENOG4105WZK	nitrite reductase NADPH small subunit
GPY22_RS18405	ENOG4105C94	Transporter
GPY22_RS18440	ENOG4105JQN	Transcriptional regulator
GPY22_RS18455	ENOG4108RCM	Nitroreductase
GPY22_RS18460	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
GPY22_RS18470	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
GPY22_RS18475	ENOG4107YCY	Transcriptional regulator
GPY22_RS18480	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GPY22_RS18490	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPY22_RS18500	ENOG4105DEI	Mannitol dehydrogenase
GPY22_RS18510	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
GPY22_RS18515	ENOG4108UHU	Aldolase
GPY22_RS18520	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GPY22_RS18525	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GPY22_RS18535	ENOG4105FFC	UPF0187 protein
GPY22_RS18540	ENOG4107RSM	transcriptional regulator
GPY22_RS18570	ENOG4107QX8	SPFH domain, Band 7 family protein
GPY22_RS18605	ENOG410642W	LysR family Transcriptional regulator
GPY22_RS18615	ENOG4105CKK	Glycosyl transferase, family 2
GPY22_RS18625	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GPY22_RS18665	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
GPY22_RS18670	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
GPY22_RS18680	ENOG4105C5W	Aldolase
GPY22_RS18685	ENOG4106RE7	Cytochrome
GPY22_RS18690	ENOG4108IG5	Transcriptional regulator
GPY22_RS18695	ENOG4105C1J	atp-dependent rna helicase
GPY22_RS18700	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
GPY22_RS18705	ENOG4105E0U	tyrosine-specific transport protein
GPY22_RS18710	ENOG4108N3W	hemolysin secretion protein
GPY22_RS18715	ENOG4105CMR	udp-glucose 4-epimerase
GPY22_RS18725	ENOG4105E7W	lamb ycsf family protein
GPY22_RS18735	ENOG4107R7A	Allophanate hydrolase subunit 2
GPY22_RS18745	ENOG4105CV6	ABC transporter, permease
GPY22_RS18750	ENOG4108I0Y	(ABC) transporter
GPY22_RS18760	ENOG4105RKW	reductase (By
GPY22_RS18775	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GPY22_RS18795	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GPY22_RS18820	ENOG4105BZU	Histidine kinase
GPY22_RS18845	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GPY22_RS18870	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
GPY22_RS18880	ENOG4105VTS	DnaJ-like, subfamily C
GPY22_RS18915	ENOG410829K	Lysine exporter protein (Lyse ygga)
GPY22_RS18935	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GPY22_RS18970	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY22_RS18980	ENOG4105N14	lysine exporter protein LysE YggA
GPY22_RS18985	ENOG4105EA8	2-Nitropropane dioxygenase
GPY22_RS18990	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GPY22_RS18995	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GPY22_RS19000	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GPY22_RS19005	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GPY22_RS19015	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
GPY22_RS19020	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GPY22_RS19025	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GPY22_RS19035	ENOG4108UHE	carbonic anhydrase
GPY22_RS19070	ENOG4105E5Q	amino acid AbC transporter
GPY22_RS19095	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GPY22_RS19115	ENOG4105GIJ	Glycine betaine
GPY22_RS19140	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GPY22_RS19155	ENOG4105D52	delta-aminolevulinic acid dehydratase
GPY22_RS19160	ENOG4105BZU	Histidine kinase
GPY22_RS19165	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GPY22_RS19175	ENOG4107R11	Transcriptional regulator
GPY22_RS19190	ENOG4105CZK	Aspartate kinase
GPY22_RS19195	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
GPY22_RS19200	ENOG4108JPW	Aminotransferase
GPY22_RS19205	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
GPY22_RS19215	ENOG4105EE5	Membrane protein terC
GPY22_RS19225	ENOG4105UQX	Mate efflux family protein
GPY22_RS19230	ENOG41090A4	Pterin carbinolamine dehydratase
GPY22_RS19235	ENOG4105MIR	Phenylalanine 4-monooxygenase
GPY22_RS19240	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GPY22_RS19250	ENOG4105DHQ	Histidine kinase
GPY22_RS19255	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
GPY22_RS19275	ENOG4108IQE	Amp-dependent synthetase and ligase
GPY22_RS19285	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GPY22_RS19310	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GPY22_RS19320	ENOG4108UKZ	OsmC family
GPY22_RS19330	ENOG4107YWA	deoxycytidylate deaminase
GPY22_RS19335	ENOG4105BZU	Histidine kinase
GPY22_RS19340	ENOG4105BZU	Histidine kinase
GPY22_RS19365	ENOG4105CXC	rtn protein
GPY22_RS19370	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GPY22_RS19375	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
GPY22_RS19400	ENOG4108XM1	transcriptional regulator AsnC family
GPY22_RS19405	ENOG4105DVH	amino acid
GPY22_RS19410	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY22_RS19415	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
GPY22_RS19420	ENOG41090JE	Utilization Protein
GPY22_RS19425	ENOG4105WQ5	TonB family
GPY22_RS19430	ENOG41090AP	transport protein
GPY22_RS19435	ENOG4106GFD	transport protein
GPY22_RS19445	ENOG4105EHG	Permease protein
GPY22_RS19450	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GPY22_RS19480	ENOG4105QVC	MOSC domain-containing protein
GPY22_RS19485	ENOG4105EKE	dihydroorotase
GPY22_RS19490	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
GPY22_RS19495	ENOG4105CKW	Inner membrane protein yedI
GPY22_RS19520	ENOG4105VJY	transcriptional regulator
GPY22_RS19525	ENOG4105NNS	Autoinducer synthesis protein
GPY22_RS19540	ENOG4105EG2	ABC transporter, permease
GPY22_RS19545	ENOG4105D56	permease protein
GPY22_RS19555	ENOG4108IJ9	(ABC) transporter
GPY22_RS19580	ENOG4108WYR	Curli production assembly transport component, CsgF
GPY22_RS19585	ENOG4105P8Q	Curli production assembly transport component CsgG
GPY22_RS19595	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GPY22_RS19605	ENOG4108HK0	-acetyltransferase
GPY22_RS19625	ENOG41080XP	Cbs domain
GPY22_RS19630	ENOG4105J4Q	Transcriptional regulator
GPY22_RS19635	ENOG4105CHR	reductase
GPY22_RS19640	ENOG4105P66	Membrane
GPY22_RS19645	ENOG4105M5J	Cupin 2, conserved barrel domain protein
GPY22_RS19660	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
GPY22_RS19665	ENOG4108UHU	Aldolase
GPY22_RS19685	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
GPY22_RS19690	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
GPY22_RS19695	ENOG4108IJ9	(ABC) transporter
GPY22_RS19700	ENOG410769Z	extracellular solute-binding protein family 1
GPY22_RS19705	ENOG41061NF	Pectate lyase
GPY22_RS19710	ENOG4105UQX	Mate efflux family protein
GPY22_RS19720	ENOG4105CAZ	oligogalacturonide lyase
GPY22_RS19725	ENOG4105K8R	UPF0145 protein
GPY22_RS19730	ENOG41086KC	Transcriptional regulator
GPY22_RS19740	ENOG4105DTR	rard protein
GPY22_RS19755	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GPY22_RS19785	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
GPY22_RS19790	ENOG4107R88	Chemotaxis protein (CheV)
GPY22_RS19795	ENOG4105MSB	protein, conserved in bacteria
GPY22_RS19800	ENOG4108ZT1	Transcriptional regulator
GPY22_RS19810	ENOG4106TD9	Diguanylate cyclase
GPY22_RS19830	ENOG4105BZU	Histidine kinase
GPY22_RS19855	ENOG4108K0B	C-di-gmp phosphodiesterase
GPY22_RS19865	ENOG4105EUB	pirin domain protein
GPY22_RS19870	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GPY22_RS19915	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GPY22_RS19975	ENOG4105CS6	Rhs element vgr protein
GPY22_RS20010	ENOG4107ZYR	domain protein
GPY22_RS20015	ENOG4105D64	Mechanosensitive ion channel
GPY22_RS20020	ENOG4105E5W	Transporter
GPY22_RS20030	ENOG4105DAN	ATP-dependent protease
GPY22_RS20040	ENOG4108JQ5	ABC transporter
GPY22_RS20045	ENOG4105CC0	LysR family Transcriptional regulator
GPY22_RS20055	ENOG4105DMF	Dehydrogenase
GPY22_RS20065	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GPY22_RS20080	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
GPY22_RS20090	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GPY22_RS20100	ENOG4105KAF	membrAne
GPY22_RS20120	ENOG4105CBN	LysR family transcriptional regulator
GPY22_RS20135	ENOG4105VSH	4-oxalocrotonate tautomerase
GPY22_RS20145	ENOG4108RXX	maleylacetoacetate isomerase
GPY22_RS20150	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GPY22_RS20160	ENOG4108594	Permease of the drug metabolite transporter
GPY22_RS20175	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GPY22_RS20185	ENOG4108K2B	transcriptional regulator
GPY22_RS20205	ENOG4105BZU	Histidine kinase
GPY22_RS20210	ENOG4105C3S	Mate efflux family protein
GPY22_RS20215	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GPY22_RS20230	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GPY22_RS20255	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
GPY22_RS20265	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GPY22_RS20280	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GPY22_RS20290	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
GPY22_RS20315	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
GPY22_RS20320	ENOG4105K56	Transcriptional regulator
GPY22_RS20325	ENOG4108ZHJ	Organic hydroperoxide resistance protein
GPY22_RS20340	ENOG4105J12	Multidrug resistance protein mdtN
GPY22_RS20360	ENOG4105EZV	Transcriptional regulator
GPY22_RS20380	ENOG4105DN9	Na H antiporter
GPY22_RS20390	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GPY22_RS20395	ENOG4105D03	DNA-3-methyladenine glycosylase II
GPY22_RS20400	ENOG4108VGI	doxx family
GPY22_RS20405	ENOG4105DZC	cytosine deaminase
GPY22_RS20430	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GPY22_RS20445	ENOG4105DR5	peptidase
GPY22_RS20450	ENOG4105CTS	PTS system mannitol-specific
GPY22_RS20455	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
GPY22_RS20460	ENOG4105E61	Mannitol repressor protein
GPY22_RS20465	ENOG4105EP9	oxidoreductase
GPY22_RS20475	ENOG4105CH2	amidohydrolase
GPY22_RS20480	ENOG4105CFC	Transporter
GPY22_RS20485	ENOG4105C5Q	Transcriptional regulator
GPY22_RS20495	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
GPY22_RS20500	ENOG4105R8A	Heat shock protein
GPY22_RS20520	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GPY22_RS20545	ENOG4105C08	Histidine kinase
GPY22_RS20555	ENOG4108ESY	Metal dependent phosphohydrolase
GPY22_RS20565	ENOG4105N1F	Hnh endonuclease
GPY22_RS20590	ENOG4107SQD	Transcriptional regulator, GntR family
GPY22_RS20600	ENOG410901E	Membrane
GPY22_RS20605	ENOG41061CK	Antibiotic biosynthesis monooxygenase
GPY22_RS20620	ENOG4105T16	Transcriptional regulator (AraC family)
GPY22_RS20630	ENOG41063TF	transcriptional regulator (AraC
GPY22_RS20635	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
GPY22_RS20640	ENOG4108RYK	Nad-dependent epimerase dehydratase
GPY22_RS20645	ENOG4105HEI	LysR family (Transcriptional regulator
GPY22_RS20655	ENOG4107SDU	Methyl-accepting chemotaxis
GPY22_RS20660	ENOG4105MVE	transcriptional regulator
GPY22_RS20665	ENOG4105ZXK	Dehydrogenase
GPY22_RS20670	ENOG4105G63	Type III effector Hrp-dependent
GPY22_RS20680	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
GPY22_RS20685	ENOG4105C6Z	Gluconate
GPY22_RS20690	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
GPY22_RS20700	ENOG4105VFU	Rna-binding protein
GPY22_RS20705	ENOG4108Z6Z	Transcriptional regulator
GPY22_RS20715	ENOG4105DMQ	Methyltransferase
GPY22_RS20720	ENOG4105ETT	transcriptional Regulator, LysR family
GPY22_RS20730	ENOG4105C1J	atp-dependent rna helicase
GPY22_RS20735	ENOG4105XA0	heptosyltransferase ii
GPY22_RS20745	ENOG4107RGH	Aldehyde dehydrogenase
GPY22_RS20750	ENOG4105EW9	transcriptional regulator AsnC family
GPY22_RS20785	ENOG4105E6M	Sulphatase-modifying factor protein
GPY22_RS20795	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GPY22_RS20815	ENOG4108JJA	ABC, transporter
GPY22_RS20825	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GPY22_RS20835	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY22_RS20850	ENOG4105BZU	Histidine kinase
GPY22_RS20860	ENOG4108V3W	Chemotaxis protein, CheW
GPY22_RS20865	ENOG4108V3W	Chemotaxis protein, CheW
GPY22_RS20870	ENOG4105CBS	Chea signal transduction histidine kinase
GPY22_RS20875	ENOG4108VYJ	response regulator receiver protein
GPY22_RS20890	ENOG4107RUE	extracellular solute-binding protein family 1
GPY22_RS20895	ENOG4106RMF	ParB family
GPY22_RS20925	ENOG4105CDY	transcriptional regulatory protein
GPY22_RS20945	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY22_RS20955	ENOG4105E2S	oxidase) subunit II
GPY22_RS20960	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GPY22_RS20965	ENOG4105CCU	oxidase (Subunit III)
GPY22_RS20970	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
GPY22_RS20975	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GPY22_RS20980	ENOG4108YYI	Protein of unknown function (DUF2810)
GPY22_RS20985	ENOG41061ZR	Transcriptional regulator
GPY22_RS20990	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GPY22_RS20995	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
GPY22_RS21000	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GPY22_RS21005	ENOG4108WC9	type VI secretion system effector, hcp1 family
GPY22_RS21010	ENOG4105CS6	Rhs element vgr protein
GPY22_RS21030	ENOG4105WJG	Glutathione
GPY22_RS21055	ENOG4105C8P	)-transporter
GPY22_RS21070	ENOG4108Q67	UPF0319 protein
GPY22_RS21085	ENOG4105FDP	GntR family transcriptional regulator
GPY22_RS21125	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
GPY22_RS21135	ENOG4105BZ1	(ABC) transporter
GPY22_RS21155	ENOG4107W52	maltose operon periplasmic protein
GPY22_RS21165	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
GPY22_RS21170	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GPY22_RS21195	ENOG4105D6U	Sodium Glutamate Symporter
GPY22_RS21200	ENOG4105YE1	PilZ domain
GPY22_RS21230	ENOG4105EFX	secretion protein, HlyD family
GPY22_RS21235	ENOG4105KK7	inner membrane protein YiaW
GPY22_RS21240	ENOG4106TD9	Diguanylate cyclase
GPY22_RS21255	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GPY22_RS21260	ENOG4107SEY	Conserved Protein
GPY22_RS21270	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GPY22_RS21285	ENOG4105C1J	atp-dependent rna helicase
GPY22_RS21290	ENOG4108N3W	hemolysin secretion protein
GPY22_RS21295	ENOG4105CVA	phosphate
GPY22_RS21300	ENOG4105C8U	phosphate abc transporter
GPY22_RS21305	ENOG4105E2Z	phosphate ABC transporter (Permease
GPY22_RS21310	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GPY22_RS21315	ENOG4108KHX	Diguanylate cyclase
GPY22_RS21330	ENOG4105CHH	sulfate transporter
GPY22_RS21350	ENOG4105BZU	Histidine kinase
GPY22_RS21360	ENOG4105E5M	Multidrug resistance protein D
GPY22_RS21370	ENOG4105VW4	glutaredoxin 3
GPY22_RS21375	ENOG4108SXK	Transporter Drug Metabolite Exporter family
GPY22_RS21380	ENOG4105E89	ABC transporter
GPY22_RS21385	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GPY22_RS21395	ENOG4108DBC	nitroreductase
GPY22_RS21400	ENOG4105VYW	UPF0251 protein
GPY22_RS21410	ENOG4105CC0	LysR family Transcriptional regulator
GPY22_RS21415	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
GPY22_RS21425	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY22_RS21455	ENOG4108HUF	Transporter
GPY22_RS21460	ENOG4105DQ5	transport system permease protein
GPY22_RS21465	ENOG4108IHU	transport system permease protein
GPY22_RS21480	ENOG4105CBN	LysR family transcriptional regulator
GPY22_RS21510	ENOG4107RH7	Nicotinate phosphoribosyltransferase
GPY22_RS21515	ENOG4105E98	transcriptional regulator DeoR family
GPY22_RS21525	ENOG41090KN	UPF0303 protein
GPY22_RS21550	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GPY22_RS21570	ENOG4105F27	Major Facilitator
GPY22_RS21580	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GPY22_RS21585	ENOG4105CV8	reductase
GPY22_RS21590	ENOG4107XTP	(EAL) domain protein
GPY22_RS21600	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPY22_RS21620	ENOG4105CY5	solute-binding protein
GPY22_RS21630	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
GPY22_RS21645	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
GPY22_RS21650	ENOG4108WUH	Transcriptional regulator, TetR family
GPY22_RS21670	ENOG4108ZT1	Transcriptional regulator
GPY22_RS21680	ENOG4105EW9	transcriptional regulator AsnC family
GPY22_RS21790	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GPY22_RS21800	ENOG4105CNN	ABC, transporter
GPY22_RS21805	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GPY22_RS21810	ENOG4108RVA	ribokinase
GPY22_RS21815	ENOG4105ETE	Transcriptional regulator (LacI family
GPY22_RS21820	ENOG4105DND	Transcriptional regulator
GPY22_RS21830	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
GPY22_RS21835	ENOG4105CXY	transporter
GPY22_RS21840	ENOG4105BZU	Histidine kinase
GPY22_RS21865	ENOG4105FDP	GntR family transcriptional regulator
GPY22_RS21880	ENOG4105BZW	Glycerate kinase
GPY22_RS21885	ENOG4105EIP	mannose-6-phosphate isomerase
GPY22_RS21905	ENOG4105D5U	fad dependent oxidoreductase
GPY22_RS21915	ENOG4105VRT	cytoplasmic protein
GPY22_RS21920	ENOG4108YZN	class I peptide chain release factor
GPY22_RS21925	ENOG4108M6U	Universal stress protein A
GPY22_RS21930	ENOG41090ED	Protein with unknown function (DUF469)
GPY22_RS21955	ENOG4105DUM	transcriptional regulator, lysR family
GPY22_RS21985	ENOG4105ECQ	AraC Family Transcriptional Regulator
GPY22_RS21995	ENOG4108T2Z	Arginine
GPY22_RS22005	ENOG4105C26	Dehydrogenase
GPY22_RS22010	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
GPY22_RS22020	ENOG4105BZU	Histidine kinase
GPY22_RS22035	ENOG4105BZU	Histidine kinase
GPY22_RS22070	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GPY22_RS22075	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY22_RS22100	ENOG4105D9N	nucleoside
GPY22_RS22115	ENOG4108JUA	Transcriptional regulator