locus-tag	class	description
GPY10_RS00005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPY10_RS00010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPY10_RS00015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPY10_RS00020	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPY10_RS00025	COG0470	DNA polymerase III
GPY10_RS00030	COG0084	hydrolase, TatD family'
GPY10_RS00035	COG2190	(PTS) system
GPY10_RS00035	COG1263	PTS System
GPY10_RS00035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY10_RS00045	COG1263	PTS System
GPY10_RS00045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY10_RS00060	COG0733	neurotransmitter:sodium symporter activity
GPY10_RS00075	COG4667	esterase of the alpha-beta hydrolase superfamily
GPY10_RS00080	COG0469	pyruvate kinase activity
GPY10_RS00085	COG1940	carbohydrate kinase activity
GPY10_RS00090	COG0784	Response regulator, receiver
GPY10_RS00090	COG0835	chemotaxis
GPY10_RS00095	COG0587	DNA-directed DNA polymerase activity
GPY10_RS00110	COG1028	Short-chain dehydrogenase reductase Sdr
GPY10_RS00115	COG0616	signal peptide processing
GPY10_RS00155	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GPY10_RS00160	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GPY10_RS00165	COG0436	Aminotransferase
GPY10_RS00170	COG1169	isochorismate synthase
GPY10_RS00175	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GPY10_RS00180	COG0596	Alpha beta hydrolase
GPY10_RS00185	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPY10_RS00190	COG1441	menaquinone biosynthetic process
GPY10_RS00205	COG2855	membrane
GPY10_RS00210	COG0477	Major facilitator Superfamily
GPY10_RS00235	COG0741	lytic transglycosylase activity
GPY10_RS00235	COG1388	LysM domain
GPY10_RS00255	COG1815	bacterial-type flagellum-dependent cell motility
GPY10_RS00260	COG1558	bacterial-type flagellum-dependent cell motility
GPY10_RS00265	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPY10_RS00270	COG1749	Flagellar hook protein flgE
GPY10_RS00280	COG4786	Flagellar basal body rod
GPY10_RS00285	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GPY10_RS00290	COG1706	bacterial-type flagellum-dependent cell motility
GPY10_RS00300	COG1256	bacterial-type flagellum assembly
GPY10_RS00300	COG4786	Flagellar basal body rod
GPY10_RS00340	COG0702	epimerase
GPY10_RS00345	COG3015	lipoprotein NlpE involved in copper resistance
GPY10_RS00355	COG1360	Flagellar Motor Protein
GPY10_RS00360	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPY10_RS00365	COG1191	sigma factor activity
GPY10_RS00370	COG1580	Controls the rotational direction of flagella during chemotaxis
GPY10_RS00390	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPY10_RS00395	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY10_RS00410	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GPY10_RS00420	COG1987	bacterial-type flagellum assembly
GPY10_RS00440	COG2885	chlorophyll binding
GPY10_RS00445	COG2204	response regulator
GPY10_RS00460	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY10_RS00485	COG1522	sequence-specific DNA binding
GPY10_RS00500	COG1946	Acyl-CoA thioesterase
GPY10_RS00505	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GPY10_RS00520	COG2203	Gaf domain
GPY10_RS00520	COG2199	diguanylate cyclase activity
GPY10_RS00540	COG1309	transcriptional regulator
GPY10_RS00560	COG4221	oxidoreductase activity
GPY10_RS00565	COG1028	Short-chain dehydrogenase reductase Sdr
GPY10_RS00575	COG1028	Short-chain dehydrogenase reductase Sdr
GPY10_RS00580	COG1028	Short-chain dehydrogenase reductase Sdr
GPY10_RS00585	COG1028	Short-chain dehydrogenase reductase Sdr
GPY10_RS00590	COG1073	alpha beta
GPY10_RS00615	COG0210	DNA helicase
GPY10_RS00625	COG0431	NADPH-dependent FMN reductase
GPY10_RS00630	COG0697	spore germination
GPY10_RS00640	COG1278	Cold shock
GPY10_RS00665	COG2207	Transcriptional regulator
GPY10_RS00670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY10_RS00675	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GPY10_RS00675	COG0674	pyruvate-flavodoxin oxidoreductase activity
GPY10_RS00680	COG1013	pyruvate-flavodoxin oxidoreductase activity
GPY10_RS00685	COG1881	PFAM PEBP family protein
GPY10_RS00690	COG2207	Transcriptional regulator
GPY10_RS00720	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY10_RS00725	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY10_RS00740	COG0642	Histidine kinase
GPY10_RS00750	COG0671	phosphoesterase, PA-phosphatase related
GPY10_RS00760	COG0513	Belongs to the DEAD box helicase family
GPY10_RS00765	COG1368	sulfuric ester hydrolase activity
GPY10_RS00770	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPY10_RS00775	COG2194	sulfuric ester hydrolase activity
GPY10_RS00795	COG4566	intracellular signal transduction
GPY10_RS00820	COG2863	cytochrome
GPY10_RS00825	COG3258	Cytochrome c
GPY10_RS00850	COG1294	oxidase, subunit
GPY10_RS00890	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPY10_RS00895	COG2814	Major facilitator Superfamily
GPY10_RS00910	COG1021	2,3-dihydroxybenzoate-AMP ligase
GPY10_RS00915	COG1169	isochorismate synthase
GPY10_RS00920	COG1028	Short-chain dehydrogenase reductase Sdr
GPY10_RS00925	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY10_RS00930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY10_RS00930	COG2226	methyltransferase
GPY10_RS00930	COG3433	isochorismatase activity
GPY10_RS00945	COG4592	Periplasmic binding protein
GPY10_RS00955	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY10_RS00960	COG1629	transport
GPY10_RS00960	COG4774	siderophore transport
GPY10_RS00970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY10_RS00975	COG1120	ATPase activity
GPY10_RS00985	COG1609	Transcriptional regulator
GPY10_RS00990	COG2723	6-phospho-beta-galactosidase activity
GPY10_RS00995	COG1741	Belongs to the pirin family
GPY10_RS01000	COG0352	thiamine-phosphate diphosphorylase activity
GPY10_RS01010	COG0351	phosphomethylpyrimidine kinase
GPY10_RS01015	COG4172	Belongs to the ABC transporter superfamily
GPY10_RS01020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY10_RS01025	COG0601	transmembrane transport
GPY10_RS01030	COG0747	negative chemotaxis
GPY10_RS01040	COG1538	Outer membrane efflux protein
GPY10_RS01045	COG1566	PFAM secretion protein HlyD family protein
GPY10_RS01050	COG2814	Major facilitator Superfamily
GPY10_RS01055	COG3708	Transcriptional regulator
GPY10_RS01055	COG2207	Transcriptional regulator
GPY10_RS01065	COG0745	RESPONSE REGULATOR receiver
GPY10_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY10_RS01075	COG1263	PTS System
GPY10_RS01085	COG1621	beta-fructofuranosidase activity
GPY10_RS01100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY10_RS01115	COG1028	Short-chain dehydrogenase reductase Sdr
GPY10_RS01150	COG2986	histidine ammonia-lyase
GPY10_RS01155	COG1216	Glycosyl transferase, family 2
GPY10_RS01175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY10_RS01180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY10_RS01185	COG0204	Acyl-transferase
GPY10_RS01185	COG0318	PFAM AMP-dependent synthetase and ligase
GPY10_RS01215	COG0601	transmembrane transport
GPY10_RS01220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY10_RS01225	COG0444	Belongs to the ABC transporter superfamily
GPY10_RS01240	COG0435	Glutathione S-transferase
GPY10_RS01245	COG3174	membrane
GPY10_RS01250	COG0280	phosphate acetyltransferase
GPY10_RS01250	COG0857	belongs to the CobB CobQ family
GPY10_RS01255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPY10_RS01260	COG3092	negative regulation of chromosome organization
GPY10_RS01270	COG4120	Belongs to the binding-protein-dependent transport system permease family
GPY10_RS01290	COG4969	Belongs to the N-Me-Phe pilin family
GPY10_RS01295	COG0653	protein targeting
GPY10_RS01300	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GPY10_RS01305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GPY10_RS01310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPY10_RS01320	COG0243	molybdopterin cofactor binding
GPY10_RS01325	COG1648	precorrin-2 dehydrogenase activity
GPY10_RS01325	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPY10_RS01345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GPY10_RS01350	COG1116	anion transmembrane transporter activity
GPY10_RS01365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GPY10_RS01370	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPY10_RS01380	COG2226	methyltransferase
GPY10_RS01385	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GPY10_RS01390	COG0501	Belongs to the peptidase M48B family
GPY10_RS01400	COG1028	Short-chain dehydrogenase reductase Sdr
GPY10_RS01415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GPY10_RS01435	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPY10_RS01440	COG2915	High frequency lysogenization protein hflD homolog
GPY10_RS01445	COG0482	sulfurtransferase activity
GPY10_RS01450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY10_RS01455	COG2916	Histone family protein nucleoid-structuring protein H-NS
GPY10_RS01460	COG1757	Na H antiporter
GPY10_RS01470	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GPY10_RS01475	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPY10_RS01480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPY10_RS01485	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPY10_RS01485	COG0131	Imidazoleglycerol-phosphate dehydratase
GPY10_RS01490	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPY10_RS01495	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPY10_RS01505	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GPY10_RS01505	COG0140	phosphoribosyl-ATP diphosphatase activity
GPY10_RS01510	COG1187	pseudouridine synthase activity
GPY10_RS01520	COG1278	Cold shock
GPY10_RS01525	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GPY10_RS01530	COG0542	response to heat
GPY10_RS01535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPY10_RS01540	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GPY10_RS01545	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GPY10_RS01555	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GPY10_RS01565	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY10_RS01570	COG0745	RESPONSE REGULATOR receiver
GPY10_RS01570	COG3706	GGDEF domain
GPY10_RS01575	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPY10_RS01580	COG0297	glycogen (starch) synthase activity
GPY10_RS01600	COG3070	regulator of competence-specific genes
GPY10_RS01605	COG1609	Transcriptional regulator
GPY10_RS01610	COG3381	protein complex oligomerization
GPY10_RS01615	COG0745	RESPONSE REGULATOR receiver
GPY10_RS01620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPY10_RS01625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY10_RS01630	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GPY10_RS01635	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GPY10_RS01640	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GPY10_RS01645	COG0189	ligase activity
GPY10_RS01655	COG4067	protein conserved in archaea
GPY10_RS01655	COG0189	ligase activity
GPY10_RS01660	COG0500	methyltransferase
GPY10_RS01665	COG4106	trans-aconitate 2-methyltransferase activity
GPY10_RS01680	COG1435	thymidine kinase activity
GPY10_RS01685	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPY10_RS01690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY10_RS01695	COG0583	DNA-binding transcription factor activity
GPY10_RS01710	COG2116	formate transmembrane transporter activity
GPY10_RS01715	COG0390	transport system, permease component
GPY10_RS01720	COG4459	periplasmic nitrate reductase
GPY10_RS01725	COG3005	denitrification pathway
GPY10_RS01730	COG0243	molybdopterin cofactor binding
GPY10_RS01750	COG1227	inorganic diphosphatase activity
GPY10_RS01765	COG4172	Belongs to the ABC transporter superfamily
GPY10_RS01775	COG4171	peptide transport system, permease
GPY10_RS01790	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GPY10_RS01795	COG1842	Phage shock protein A
GPY10_RS01810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY10_RS01825	COG0519	Catalyzes the synthesis of GMP from XMP
GPY10_RS01855	COG0626	cystathionine gamma-synthase activity
GPY10_RS01865	COG0733	neurotransmitter:sodium symporter activity
GPY10_RS01885	COG0564	pseudouridine synthase activity
GPY10_RS01900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPY10_RS01905	COG4136	ATPase activity
GPY10_RS01910	COG4135	transport system, permease component
GPY10_RS01915	COG4134	Bacterial extracellular solute-binding protein
GPY10_RS01925	COG3313	Fe-S protein
GPY10_RS01935	COG0842	Transport permease protein
GPY10_RS01940	COG1131	(ABC) transporter
GPY10_RS01950	COG0814	amino acid
GPY10_RS01965	COG3706	GGDEF domain
GPY10_RS01970	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPY10_RS01980	COG1278	Cold shock
GPY10_RS02000	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GPY10_RS02005	COG2205	protein histidine kinase activity
GPY10_RS02010	COG0745	RESPONSE REGULATOR receiver
GPY10_RS02020	COG1061	Type III restriction enzyme res subunit
GPY10_RS02030	COG2814	Major facilitator Superfamily
GPY10_RS02040	COG0702	epimerase
GPY10_RS02045	COG0534	Mate efflux family protein
GPY10_RS02050	COG4181	ATPase activity
GPY10_RS02065	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPY10_RS02115	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPY10_RS02125	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GPY10_RS02130	COG3265	gluconokinase activity
GPY10_RS02165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY10_RS02185	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY10_RS02210	COG2989	Protein conserved in bacteria
GPY10_RS02215	COG3108	Peptidase M15
GPY10_RS02220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY10_RS02235	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPY10_RS02255	COG2197	response regulator
GPY10_RS02260	COG1846	Transcriptional regulator
GPY10_RS02265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY10_RS02270	COG0840	transmembrane signaling receptor activity
GPY10_RS02275	COG2176	DNA-directed DNA polymerase activity
GPY10_RS02280	COG0517	IMP dehydrogenase activity
GPY10_RS02290	COG1448	Aminotransferase
GPY10_RS02305	COG0017	Asparaginyl-tRNA synthetase
GPY10_RS02310	COG0840	transmembrane signaling receptor activity
GPY10_RS02315	COG0720	synthase
GPY10_RS02320	COG1538	Outer membrane efflux protein
GPY10_RS02325	COG0577	efflux transmembrane transporter activity
GPY10_RS02325	COG1136	(ABC) transporter
GPY10_RS02330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY10_RS02335	COG1760	l-serine dehydratase
GPY10_RS02340	COG0814	amino acid
GPY10_RS02345	COG0494	nUDIX hydrolase
GPY10_RS02360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY10_RS02375	COG3106	COG3106 Predicted ATPase
GPY10_RS02380	COG3768	UPF0283 membrane protein
GPY10_RS02385	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GPY10_RS02390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY10_RS02415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY10_RS02415	COG4191	Histidine kinase
GPY10_RS02425	COG0583	DNA-binding transcription factor activity
GPY10_RS02430	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GPY10_RS02435	COG0778	Nitroreductase
GPY10_RS02440	COG2991	Protein conserved in bacteria
GPY10_RS02450	COG3250	beta-galactosidase activity
GPY10_RS02460	COG1129	ABC transporter
GPY10_RS02500	COG2169	Transcriptional regulator
GPY10_RS02500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPY10_RS02510	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPY10_RS02515	COG0372	Belongs to the citrate synthase family
GPY10_RS02520	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GPY10_RS02525	COG2828	Protein conserved in bacteria
GPY10_RS02540	COG1566	PFAM secretion protein HlyD family protein
GPY10_RS02545	COG2814	Major facilitator Superfamily
GPY10_RS02560	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY10_RS02565	COG2200	EAL domain
GPY10_RS02575	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GPY10_RS02585	COG0625	glutathione transferase activity
GPY10_RS02605	COG2731	YhcH YjgK YiaL family protein
GPY10_RS02615	COG0584	glycerophosphoryl diester phosphodiesterase
GPY10_RS02620	COG1349	DNA-binding transcription factor activity
GPY10_RS02625	COG3842	ATPase activity
GPY10_RS02630	COG0395	ABC-type sugar transport system, permease component
GPY10_RS02650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY10_RS02655	COG3040	lipid binding
GPY10_RS02665	COG0811	peptide transport
GPY10_RS02670	COG0811	peptide transport
GPY10_RS02675	COG0848	biopolymer transport protein
GPY10_RS02695	COG4667	esterase of the alpha-beta hydrolase superfamily
GPY10_RS02700	COG1793	dna ligase
GPY10_RS02715	COG0307	riboflavin synthase, alpha
GPY10_RS02735	COG0791	NLP P60 protein
GPY10_RS02740	COG0840	transmembrane signaling receptor activity
GPY10_RS02755	COG1940	carbohydrate kinase activity
GPY10_RS02765	COG0303	'Molybdopterin
GPY10_RS02770	COG0746	molybdenum cofactor guanylyltransferase activity
GPY10_RS02775	COG3842	ATPase activity
GPY10_RS02780	COG4662	Binding-protein-dependent transport system inner membrane component
GPY10_RS02790	COG2204	response regulator
GPY10_RS02795	COG3852	Histidine kinase
GPY10_RS02810	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPY10_RS02830	COG3381	protein complex oligomerization
GPY10_RS02845	COG0437	4 iron, 4 sulfur cluster binding
GPY10_RS02860	COG0004	ammonium transporteR
GPY10_RS02865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GPY10_RS02870	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY10_RS02875	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY10_RS02880	COG1177	transmembrane transport
GPY10_RS02885	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPY10_RS02890	COG3842	ATPase activity
GPY10_RS02915	COG0589	response to stress
GPY10_RS02920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY10_RS02935	COG2217	Heavy metal translocating P-type atpase
GPY10_RS02945	COG2010	Cytochrome c
GPY10_RS03050	COG3120	sequence-specific DNA binding
GPY10_RS03055	COG1067	ATP-dependent peptidase activity
GPY10_RS03060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY10_RS03085	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY10_RS03085	COG0116	Belongs to the methyltransferase superfamily
GPY10_RS03095	COG0167	dihydroorotate dehydrogenase activity
GPY10_RS03110	COG0308	aminopeptidase N
GPY10_RS03135	COG1956	GAF domain-containing protein
GPY10_RS03140	COG1132	(ABC) transporter
GPY10_RS03145	COG2995	paraquat-inducible protein a
GPY10_RS03155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPY10_RS03155	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GPY10_RS03160	COG2996	Protein conserved in bacteria
GPY10_RS03175	COG0574	Belongs to the PEP-utilizing enzyme family
GPY10_RS03175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPY10_RS03180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY10_RS03205	COG1115	amino acid carrier protein
GPY10_RS03230	COG3501	Rhs element vgr protein
GPY10_RS03240	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GPY10_RS03250	COG1643	Atp-dependent helicase
GPY10_RS03255	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPY10_RS03265	COG3005	denitrification pathway
GPY10_RS03305	COG0443	Heat shock 70 kDa protein
GPY10_RS03310	COG3706	GGDEF domain
GPY10_RS03320	COG5001	Diguanylate cyclase
GPY10_RS03320	COG3300	MHYT domain
GPY10_RS03335	COG2999	glutathione oxidoreductase activity
GPY10_RS03355	COG3706	GGDEF domain
GPY10_RS03355	COG0745	RESPONSE REGULATOR receiver
GPY10_RS03365	COG0243	molybdopterin cofactor binding
GPY10_RS03370	COG3005	denitrification pathway
GPY10_RS03380	COG0602	queuosine metabolic process
GPY10_RS03385	COG0561	phosphatase activity
GPY10_RS03395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY10_RS03400	COG4597	amino acid ABC transporter
GPY10_RS03405	COG0765	amino acid transport
GPY10_RS03410	COG1126	abc transporter atp-binding protein
GPY10_RS03415	COG0670	Belongs to the BI1 family
GPY10_RS03420	COG2920	part of a sulfur-relay system
GPY10_RS03425	COG1254	Belongs to the acylphosphatase family
GPY10_RS03430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY10_RS03435	COG3391	amine dehydrogenase activity
GPY10_RS03455	COG2010	Cytochrome c
GPY10_RS03480	COG5002	protein histidine kinase activity
GPY10_RS03500	COG0668	transmembrane transport
GPY10_RS03535	COG1278	Cold shock
GPY10_RS03655	COG1619	proteins homologs of microcin C7 resistance protein MccF
GPY10_RS03660	COG4695	Portal protein
GPY10_RS03700	COG4386	tail sheath protein
GPY10_RS03740	COG3706	GGDEF domain
GPY10_RS03740	COG0745	RESPONSE REGULATOR receiver
GPY10_RS03755	COG0835	chemotaxis
GPY10_RS03755	COG0784	Response regulator, receiver
GPY10_RS03765	COG4565	transcriptional regulatory protein
GPY10_RS03770	COG3290	protein histidine kinase activity
GPY10_RS03785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY10_RS03805	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GPY10_RS03810	COG3063	Type IV pilus biogenesis stability protein PilW
GPY10_RS03825	COG1451	nucleotide metabolic process
GPY10_RS03835	COG0583	DNA-binding transcription factor activity
GPY10_RS03895	COG2988	succinylglutamate desuccinylase activity
GPY10_RS03910	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GPY10_RS03915	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GPY10_RS03920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GPY10_RS03925	COG0702	epimerase
GPY10_RS03940	COG2925	Exonuclease
GPY10_RS03950	COG1346	cytolysis
GPY10_RS03955	COG0295	cytidine deaminase activity
GPY10_RS03960	COG5001	Diguanylate cyclase
GPY10_RS03980	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GPY10_RS03990	COG0500	methyltransferase
GPY10_RS04000	COG0776	regulation of translation
GPY10_RS04005	COG0072	phenylalanine-tRNA ligase activity
GPY10_RS04005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY10_RS04010	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPY10_RS04025	COG3706	GGDEF domain
GPY10_RS04025	COG0745	RESPONSE REGULATOR receiver
GPY10_RS04030	COG2133	pyrroloquinoline quinone binding
GPY10_RS04065	COG2197	response regulator
GPY10_RS04070	COG0417	DNA replication proofreading
GPY10_RS04075	COG5001	Diguanylate cyclase
GPY10_RS04085	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPY10_RS04105	COG1228	amidohydrolase
GPY10_RS04110	COG0010	Belongs to the arginase family
GPY10_RS04120	COG2986	histidine ammonia-lyase
GPY10_RS04140	COG0247	lactate metabolic process
GPY10_RS04140	COG0277	FAD linked oxidase domain protein
GPY10_RS04155	COG2885	chlorophyll binding
GPY10_RS04190	COG2957	Belongs to the agmatine deiminase family
GPY10_RS04200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY10_RS04205	COG1012	belongs to the aldehyde dehydrogenase family
GPY10_RS04210	COG1917	Cupin 2, conserved barrel domain protein
GPY10_RS04210	COG1396	sequence-specific DNA binding
GPY10_RS04215	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GPY10_RS04225	COG1757	Na H antiporter
GPY10_RS04235	COG1643	Atp-dependent helicase
GPY10_RS04240	COG0281	malic enzyme
GPY10_RS04265	COG0583	DNA-binding transcription factor activity
GPY10_RS04280	COG0640	Transcriptional regulator
GPY10_RS04305	COG2949	membrane
GPY10_RS04315	COG1414	Transcriptional regulator
GPY10_RS04320	COG1414	Transcriptional regulator
GPY10_RS04330	COG1454	alcohol dehydrogenase
GPY10_RS04335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPY10_RS04355	COG0492	ferredoxin-NADP+ reductase activity
GPY10_RS04360	COG4988	ABC transporter
GPY10_RS04365	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GPY10_RS04400	COG1187	pseudouridine synthase activity
GPY10_RS04405	COG0009	L-threonylcarbamoyladenylate synthase
GPY10_RS04410	COG0613	PHP domain protein
GPY10_RS04420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY10_RS04425	COG0512	Glutamine amidotransferase of anthranilate synthase
GPY10_RS04430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPY10_RS04435	COG0135	phosphoribosylanthranilate isomerase activity
GPY10_RS04435	COG0134	indole-3-glycerol-phosphate synthase activity
GPY10_RS04440	COG0133	tryptophan synthase activity
GPY10_RS04450	COG1301	dicarboxylic acid transport
GPY10_RS04465	COG1607	acyl-coa hydrolase
GPY10_RS04470	COG2350	Protein conserved in bacteria
GPY10_RS04480	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPY10_RS04485	COG0583	DNA-binding transcription factor activity
GPY10_RS04500	COG0612	Peptidase, M16
GPY10_RS04520	COG0625	glutathione transferase activity
GPY10_RS04530	COG2771	luxR family
GPY10_RS04530	COG2200	EAL domain
GPY10_RS04535	COG0840	transmembrane signaling receptor activity
GPY10_RS04550	COG1794	racemase activity, acting on amino acids and derivatives
GPY10_RS04555	COG0346	lactoylglutathione lyase activity
GPY10_RS04560	COG5002	protein histidine kinase activity
GPY10_RS04565	COG0745	RESPONSE REGULATOR receiver
GPY10_RS04585	COG0488	(ABC) transporter
GPY10_RS04590	COG1032	radical SAM domain protein
GPY10_RS04595	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPY10_RS04605	COG3852	Histidine kinase
GPY10_RS04620	COG3070	regulator of competence-specific genes
GPY10_RS04630	COG2431	L-lysine efflux transmembrane transporter activity
GPY10_RS04640	COG0076	glutamate decarboxylase activity
GPY10_RS04645	COG1737	Transcriptional regulator
GPY10_RS04655	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY10_RS04665	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPY10_RS04690	COG1012	belongs to the aldehyde dehydrogenase family
GPY10_RS04715	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GPY10_RS04720	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GPY10_RS04725	COG2885	chlorophyll binding
GPY10_RS04745	COG0811	peptide transport
GPY10_RS04750	COG0824	Thioesterase
GPY10_RS04760	COG4890	Cyd operon protein YbgT
GPY10_RS04765	COG1294	oxidase, subunit
GPY10_RS04770	COG1271	oxidase subunit
GPY10_RS04775	COG2255	four-way junction helicase activity
GPY10_RS04780	COG0632	four-way junction helicase activity
GPY10_RS04785	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GPY10_RS04790	COG0215	cysteine-tRNA ligase activity
GPY10_RS04795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPY10_RS04800	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY10_RS04805	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY10_RS04810	COG3012	SEC-C Motif Domain Protein
GPY10_RS04820	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPY10_RS04825	COG1199	ATP-dependent helicase activity
GPY10_RS04850	COG4160	amino acid transport
GPY10_RS04855	COG4215	(ABC) transporter
GPY10_RS04875	COG1882	Formate acetyltransferase
GPY10_RS04890	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY10_RS04910	COG2766	serine protein kinase
GPY10_RS04915	COG2718	Belongs to the UPF0229 family
GPY10_RS04920	COG2719	SpoVR family
GPY10_RS04925	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GPY10_RS04940	COG1132	(ABC) transporter
GPY10_RS04945	COG2333	competence protein COMEC
GPY10_RS04945	COG0658	competence protein
GPY10_RS04955	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPY10_RS04960	COG1136	(ABC) transporter
GPY10_RS04975	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPY10_RS04990	COG1252	NADH dehydrogenase
GPY10_RS05020	COG0537	adenosine 5'-monophosphoramidase activity
GPY10_RS05035	COG2186	Transcriptional regulator
GPY10_RS05040	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPY10_RS05045	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GPY10_RS05050	COG1674	ftsk spoiiie
GPY10_RS05055	COG1522	sequence-specific DNA binding
GPY10_RS05060	COG0686	Belongs to the AlaDH PNT family
GPY10_RS05070	COG0583	DNA-binding transcription factor activity
GPY10_RS05090	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GPY10_RS05095	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GPY10_RS05105	COG0539	negative regulation of cytoplasmic translation
GPY10_RS05110	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GPY10_RS05115	COG1555	photosystem II stabilization
GPY10_RS05120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY10_RS05125	COG0776	regulation of translation
GPY10_RS05130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPY10_RS05135	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPY10_RS05145	COG0544	peptidyl-prolyl cis-trans isomerase activity
GPY10_RS05155	COG2204	response regulator
GPY10_RS05165	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GPY10_RS05170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPY10_RS05190	COG0745	RESPONSE REGULATOR receiver
GPY10_RS05195	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GPY10_RS05200	COG1760	l-serine dehydratase
GPY10_RS05210	COG3153	acetyltransferase
GPY10_RS05210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPY10_RS05220	COG1716	ATPase activity
GPY10_RS05220	COG5001	Diguanylate cyclase
GPY10_RS05230	COG4589	Belongs to the CDS family
GPY10_RS05265	COG2197	response regulator
GPY10_RS05270	COG3851	Histidine kinase
GPY10_RS05275	COG2271	Major facilitator Superfamily
GPY10_RS05280	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY10_RS05290	COG3842	ATPase activity
GPY10_RS05300	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPY10_RS05305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY10_RS05315	COG2951	lytic endotransglycosylase activity
GPY10_RS05320	COG3100	YcgL domain-containing protein
GPY10_RS05330	COG2894	cell division
GPY10_RS05335	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GPY10_RS05350	COG0318	PFAM AMP-dependent synthetase and ligase
GPY10_RS05370	COG1214	PFAM Peptidase M22, glycoprotease
GPY10_RS05375	COG1199	ATP-dependent helicase activity
GPY10_RS05385	COG0788	formyltetrahydrofolate deformylase activity
GPY10_RS05395	COG0616	signal peptide processing
GPY10_RS05400	COG0252	asparaginase activity
GPY10_RS05405	COG3139	Protein of unknown function (DUF1315)
GPY10_RS05415	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY10_RS05420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY10_RS05430	COG2226	methyltransferase
GPY10_RS05460	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPY10_RS05465	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPY10_RS05470	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPY10_RS05480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPY10_RS05485	COG2832	Protein of unknown function (DUF454)
GPY10_RS05495	COG0745	RESPONSE REGULATOR receiver
GPY10_RS05500	COG0583	DNA-binding transcription factor activity
GPY10_RS05505	COG0778	Nitroreductase
GPY10_RS05510	COG1024	Enoyl-CoA hydratase
GPY10_RS05510	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPY10_RS05515	COG0183	Belongs to the thiolase family
GPY10_RS05530	COG2067	long-chain fatty acid transport protein
GPY10_RS05535	COG2067	long-chain fatty acid transport protein
GPY10_RS05540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPY10_RS05555	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GPY10_RS05560	COG2982	Protein involved in outer membrane biogenesis
GPY10_RS05565	COG0572	uridine kinase
GPY10_RS05570	COG0489	protein tyrosine kinase activity
GPY10_RS05575	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY10_RS05575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY10_RS05585	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GPY10_RS05595	COG0517	IMP dehydrogenase activity
GPY10_RS05595	COG0516	GMP reductase activity
GPY10_RS05600	COG3706	GGDEF domain
GPY10_RS05605	COG0314	molybdopterin synthase activity
GPY10_RS05610	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPY10_RS05615	COG0315	cyclic pyranopterin monophosphate synthase activity
GPY10_RS05620	COG0521	Mo-molybdopterin cofactor biosynthetic process
GPY10_RS05625	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPY10_RS05630	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GPY10_RS05635	COG2198	Histidine kinase
GPY10_RS05640	COG2204	response regulator
GPY10_RS05655	COG4657	Part of a membrane complex involved in electron transport
GPY10_RS05660	COG2878	Part of a membrane complex involved in electron transport
GPY10_RS05665	COG4656	Part of a membrane complex involved in electron transport
GPY10_RS05670	COG4658	electron transport chain
GPY10_RS05680	COG4660	Part of a membrane complex involved in electron transport
GPY10_RS05685	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPY10_RS05690	COG0346	lactoylglutathione lyase activity
GPY10_RS05705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPY10_RS05710	COG2056	Na+-H+ antiporter family
GPY10_RS05715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPY10_RS05720	COG1286	toxin biosynthetic process
GPY10_RS05725	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GPY10_RS05740	COG0101	tRNA pseudouridine synthase activity
GPY10_RS05750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY10_RS05755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY10_RS05755	COG2190	(PTS) system
GPY10_RS05755	COG1263	PTS System
GPY10_RS05760	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPY10_RS05770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPY10_RS05770	COG4651	solute:proton antiporter activity
GPY10_RS05775	COG0367	asparagine synthase
GPY10_RS05785	COG3104	oligopeptide transport
GPY10_RS05790	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GPY10_RS05800	COG0326	Molecular chaperone. Has ATPase activity
GPY10_RS05805	COG3710	Transcriptional regulator
GPY10_RS05820	COG0622	Phosphoesterase
GPY10_RS05845	COG1090	epimerase
GPY10_RS05850	COG0300	oxidoreductase activity
GPY10_RS05860	COG3118	belongs to the thioredoxin family
GPY10_RS05865	COG0330	HflC and HflK could
GPY10_RS05875	COG0789	Transcriptional regulator
GPY10_RS05890	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPY10_RS05895	COG3115	cell septum assembly
GPY10_RS05900	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GPY10_RS05905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPY10_RS05915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY10_RS05925	COG2190	(PTS) system
GPY10_RS05930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY10_RS05940	COG1702	phosphate starvation-inducible protein PhoH
GPY10_RS05945	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPY10_RS05950	COG4535	Mg2 and Co2 transporter CorC
GPY10_RS05955	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GPY10_RS05960	COG2888	peptidyl-tyrosine sulfation
GPY10_RS05970	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GPY10_RS05975	COG1466	dna polymerase III delta subunit
GPY10_RS05980	COG0799	negative regulation of ribosome biogenesis
GPY10_RS05985	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPY10_RS05990	COG0768	penicillin binding
GPY10_RS05995	COG0772	Belongs to the SEDS family
GPY10_RS06000	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPY10_RS06005	COG1686	Belongs to the peptidase S11 family
GPY10_RS06010	COG2921	Belongs to the UPF0250 family
GPY10_RS06015	COG0321	lipoyl(octanoyl) transferase activity
GPY10_RS06020	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GPY10_RS06030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPY10_RS06045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY10_RS06070	COG0366	Alpha amylase catalytic
GPY10_RS06075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY10_RS06075	COG1263	PTS System
GPY10_RS06090	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPY10_RS06095	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPY10_RS06100	COG2011	ABC-type metal ion transport system permease component
GPY10_RS06105	COG1464	Belongs to the NlpA lipoprotein family
GPY10_RS06110	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GPY10_RS06120	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPY10_RS06120	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPY10_RS06130	COG3706	GGDEF domain
GPY10_RS06130	COG0745	RESPONSE REGULATOR receiver
GPY10_RS06135	COG1611	Belongs to the LOG family
GPY10_RS06140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY10_RS06150	COG2363	Small membrane protein
GPY10_RS06160	COG0583	DNA-binding transcription factor activity
GPY10_RS06165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY10_RS06165	COG0301	tRNA thio-modification
GPY10_RS06175	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPY10_RS06185	COG0142	geranyltranstransferase activity
GPY10_RS06190	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPY10_RS06195	COG0564	pseudouridine synthase activity
GPY10_RS06200	COG3098	single-species biofilm formation
GPY10_RS06225	COG1671	Belongs to the UPF0178 family
GPY10_RS06230	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY10_RS06235	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GPY10_RS06240	COG0254	rRNA binding
GPY10_RS06245	COG1720	tRNA m6t6A37 methyltransferase activity
GPY10_RS06250	COG0442	prolyl-tRNA aminoacylation
GPY10_RS06275	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GPY10_RS06280	COG0590	tRNA wobble adenosine to inosine editing
GPY10_RS06285	COG0583	DNA-binding transcription factor activity
GPY10_RS06290	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GPY10_RS06295	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GPY10_RS06300	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY10_RS06335	COG0443	Heat shock 70 kDa protein
GPY10_RS06345	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPY10_RS06350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPY10_RS06355	COG0497	DNA recombination
GPY10_RS06360	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY10_RS06365	COG2914	Belongs to the UPF0125 (RnfH) family
GPY10_RS06370	COG2867	negative regulation of translational initiation
GPY10_RS06375	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GPY10_RS06390	COG0328	RNA-DNA hybrid ribonuclease activity
GPY10_RS06420	COG0582	viral genome integration into host DNA
GPY10_RS06480	COG0583	DNA-binding transcription factor activity
GPY10_RS06485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY10_RS06490	COG1115	amino acid carrier protein
GPY10_RS06500	COG1473	amidohydrolase
GPY10_RS06515	COG1584	GPR1 FUN34 yaaH family protein
GPY10_RS06525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GPY10_RS06525	COG0519	Catalyzes the synthesis of GMP from XMP
GPY10_RS06530	COG0516	GMP reductase activity
GPY10_RS06530	COG0517	IMP dehydrogenase activity
GPY10_RS06535	COG1570	exodeoxyribonuclease VII activity
GPY10_RS06550	COG1160	GTP binding
GPY10_RS06555	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY10_RS06560	COG2976	Protein conserved in bacteria
GPY10_RS06565	COG0124	histidyl-tRNA synthetase
GPY10_RS06575	COG1426	Protein conserved in bacteria
GPY10_RS06590	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPY10_RS06595	COG2975	iron-sulfur cluster assembly
GPY10_RS06600	COG0633	Ferredoxin
GPY10_RS06605	COG0443	Heat shock 70 kDa protein
GPY10_RS06620	COG0822	iron-sulfur transferase activity
GPY10_RS06625	COG1104	cysteine desulfurase activity
GPY10_RS06630	COG1959	2 iron, 2 sulfur cluster binding
GPY10_RS06635	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GPY10_RS06640	COG0483	inositol monophosphate 1-phosphatase activity
GPY10_RS06645	COG1335	isochorismatase
GPY10_RS06650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY10_RS06655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY10_RS06660	COG1862	Preprotein translocase
GPY10_RS06665	COG0343	queuine tRNA-ribosyltransferase activity
GPY10_RS06670	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPY10_RS06675	COG0517	IMP dehydrogenase activity
GPY10_RS06685	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GPY10_RS06690	COG0583	DNA-binding transcription factor activity
GPY10_RS06695	COG0450	alkyl hydroperoxide reductase
GPY10_RS06710	COG0704	Plays a role in the regulation of phosphate uptake
GPY10_RS06715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY10_RS06720	COG0581	inorganic phosphate transmembrane transporter activity
GPY10_RS06725	COG0573	inorganic phosphate transmembrane transporter activity
GPY10_RS06730	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GPY10_RS06735	COG0248	Ppx GppA phosphatase
GPY10_RS06745	COG5002	protein histidine kinase activity
GPY10_RS06750	COG0745	RESPONSE REGULATOR receiver
GPY10_RS06755	COG2974	May be involved in recombination
GPY10_RS06765	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPY10_RS06780	COG1595	DNA-templated transcription, initiation
GPY10_RS06790	COG3248	Nucleoside-binding outer membrane protein
GPY10_RS06795	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPY10_RS06805	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPY10_RS06820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GPY10_RS06825	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GPY10_RS06835	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPY10_RS06835	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPY10_RS06850	COG1074	ATP-dependent DNA helicase activity
GPY10_RS06865	COG0583	DNA-binding transcription factor activity
GPY10_RS06870	COG3141	response to X-ray
GPY10_RS06875	COG2171	N-acyltransferase activity
GPY10_RS06880	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPY10_RS06895	COG0189	ligase activity
GPY10_RS06895	COG0569	domain protein
GPY10_RS06910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY10_RS06930	COG3437	response regulator, receiver
GPY10_RS06930	COG0784	Response regulator, receiver
GPY10_RS06980	COG4964	Belongs to the GSP D family
GPY10_RS07020	COG0583	DNA-binding transcription factor activity
GPY10_RS07040	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPY10_RS07050	COG0560	Phosphoserine phosphatase
GPY10_RS07060	COG0813	purine-nucleoside phosphorylase activity
GPY10_RS07065	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPY10_RS07070	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GPY10_RS07075	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPY10_RS07080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY10_RS07105	COG0084	hydrolase, TatD family'
GPY10_RS07110	COG3022	response to hydroperoxide
GPY10_RS07150	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPY10_RS07155	COG0083	homoserine kinase activity
GPY10_RS07180	COG0745	RESPONSE REGULATOR receiver
GPY10_RS07190	COG5002	protein histidine kinase activity
GPY10_RS07190	COG2198	Histidine kinase
GPY10_RS07190	COG0784	Response regulator, receiver
GPY10_RS07195	COG3706	GGDEF domain
GPY10_RS07195	COG2203	Gaf domain
GPY10_RS07195	COG5001	Diguanylate cyclase
GPY10_RS07195	COG4251	negative regulation of phosphorylation
GPY10_RS07200	COG1242	4 iron, 4 sulfur cluster binding
GPY10_RS07205	COG0069	glutamate synthase activity
GPY10_RS07205	COG0067	glutamate synthase
GPY10_RS07205	COG0070	glutamate synthase
GPY10_RS07215	COG0070	glutamate synthase
GPY10_RS07215	COG0069	glutamate synthase activity
GPY10_RS07215	COG0067	glutamate synthase
GPY10_RS07220	COG0493	'glutamate synthase
GPY10_RS07240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY10_RS07245	COG2860	membrane
GPY10_RS07265	COG0583	DNA-binding transcription factor activity
GPY10_RS07270	COG0730	response to heat
GPY10_RS07280	COG0505	Belongs to the CarA family
GPY10_RS07290	COG0494	nUDIX hydrolase
GPY10_RS07295	COG0653	protein targeting
GPY10_RS07305	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GPY10_RS07310	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPY10_RS07315	COG0849	cell division
GPY10_RS07320	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GPY10_RS07325	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPY10_RS07330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPY10_RS07335	COG0772	Belongs to the SEDS family
GPY10_RS07340	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPY10_RS07345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPY10_RS07350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GPY10_RS07355	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPY10_RS07360	COG0768	penicillin binding
GPY10_RS07365	COG3116	cell division
GPY10_RS07370	COG0275	rRNA processing
GPY10_RS07380	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPY10_RS07385	COG3107	peptidoglycan biosynthetic process
GPY10_RS07390	COG0792	nuclease activity
GPY10_RS07395	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPY10_RS07400	COG2823	Periplasmic or secreted lipoprotein
GPY10_RS07405	COG2969	positive regulation of protein catabolic process
GPY10_RS07410	COG0625	glutathione transferase activity
GPY10_RS07415	COG2857	Cytochrome c1
GPY10_RS07420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GPY10_RS07425	COG0723	plastoquinol--plastocyanin reductase activity
GPY10_RS07430	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GPY10_RS07435	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPY10_RS07445	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GPY10_RS07450	COG3105	Protein conserved in bacteria
GPY10_RS07455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPY10_RS07460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPY10_RS07465	COG0335	large ribosomal subunit rRNA binding
GPY10_RS07475	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPY10_RS07485	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPY10_RS07490	COG4137	Cytochrome C assembly protein
GPY10_RS07495	COG4536	flavin adenine dinucleotide binding
GPY10_RS07500	COG1854	S-ribosylhomocysteine lyase activity
GPY10_RS07515	COG0612	Peptidase, M16
GPY10_RS07525	COG1063	alcohol dehydrogenase
GPY10_RS07530	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPY10_RS07535	COG0511	ligase activity, forming carbon-carbon bonds
GPY10_RS07535	COG5016	pyruvate
GPY10_RS07540	COG3630	sodium ion export across plasma membrane
GPY10_RS07590	COG0527	aspartate kinase activity
GPY10_RS07595	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPY10_RS07605	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPY10_RS07610	COG1546	Belongs to the CinA family
GPY10_RS07615	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPY10_RS07620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPY10_RS07625	COG1388	LysM domain
GPY10_RS07625	COG4942	peptidase
GPY10_RS07635	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GPY10_RS07640	COG0585	pseudouridine synthase activity
GPY10_RS07650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPY10_RS07655	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GPY10_RS07660	COG1968	undecaprenyl-diphosphatase activity
GPY10_RS07665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY10_RS07670	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPY10_RS07675	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GPY10_RS07685	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPY10_RS07690	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GPY10_RS07695	COG1610	YqeY-like protein
GPY10_RS07705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPY10_RS07725	COG3206	protein involved in exopolysaccharide biosynthesis
GPY10_RS07725	COG0489	protein tyrosine kinase activity
GPY10_RS07735	COG1596	polysaccharide export
GPY10_RS07760	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPY10_RS07765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GPY10_RS07770	COG1349	DNA-binding transcription factor activity
GPY10_RS07775	COG0469	pyruvate kinase activity
GPY10_RS07780	COG3706	GGDEF domain
GPY10_RS07805	COG0668	transmembrane transport
GPY10_RS07810	COG0191	fructose-bisphosphate aldolase activity
GPY10_RS07815	COG0126	phosphoglycerate kinase activity
GPY10_RS07820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY10_RS07825	COG4771	TonB-dependent receptor
GPY10_RS07830	COG0583	DNA-binding transcription factor activity
GPY10_RS07840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPY10_RS07860	COG2356	endonuclease I
GPY10_RS07865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GPY10_RS07870	COG0189	ligase activity
GPY10_RS07875	COG1678	Uncharacterized ACR, COG1678
GPY10_RS07880	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPY10_RS07895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPY10_RS07900	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPY10_RS07905	COG0762	integral membrane protein
GPY10_RS07910	COG1872	DUF167
GPY10_RS07925	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY10_RS07930	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GPY10_RS07935	COG2066	Belongs to the glutaminase family
GPY10_RS07940	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GPY10_RS07945	COG1194	a g-specific adenine glycosylase
GPY10_RS07950	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GPY10_RS07955	COG0741	lytic transglycosylase activity
GPY10_RS08010	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPY10_RS08015	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GPY10_RS08020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY10_RS08035	COG2967	ApaG domain
GPY10_RS08050	COG3610	response to peptide
GPY10_RS08055	COG2966	Psort location CytoplasmicMembrane, score
GPY10_RS08060	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPY10_RS08065	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GPY10_RS08070	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GPY10_RS08075	COG0142	geranyltranstransferase activity
GPY10_RS08080	COG0531	amino acid
GPY10_RS08085	COG0039	L-malate dehydrogenase activity
GPY10_RS08105	COG0589	response to stress
GPY10_RS08130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPY10_RS08140	COG1530	ribonuclease E activity
GPY10_RS08145	COG0424	maF-like protein
GPY10_RS08150	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GPY10_RS08155	COG1792	Involved in formation and maintenance of cell shape
GPY10_RS08160	COG1077	Cell shape determining protein MreB Mrl
GPY10_RS08190	COG4969	Belongs to the N-Me-Phe pilin family
GPY10_RS08210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY10_RS08245	COG2199	diguanylate cyclase activity
GPY10_RS08245	COG2200	EAL domain
GPY10_RS08250	COG0629	single-stranded DNA binding
GPY10_RS08255	COG2197	response regulator
GPY10_RS08265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPY10_RS08275	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPY10_RS08280	COG0527	aspartate kinase activity
GPY10_RS08285	COG0646	methionine synthase
GPY10_RS08285	COG1410	methionine synthase
GPY10_RS08355	COG0175	sulfate reduction
GPY10_RS08365	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY10_RS08385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY10_RS08390	COG0735	belongs to the Fur family
GPY10_RS08400	COG0166	Belongs to the GPI family
GPY10_RS08405	COG0432	Pfam Uncharacterised protein family UPF0047
GPY10_RS08410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY10_RS08415	COG0305	Participates in initiation and elongation during chromosome replication
GPY10_RS08425	COG0359	binds to the 23S rRNA
GPY10_RS08435	COG2965	DNA replication, synthesis of RNA primer
GPY10_RS08440	COG0360	Binds together with S18 to 16S ribosomal RNA
GPY10_RS08450	COG2906	2 iron, 2 sulfur cluster binding
GPY10_RS08460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPY10_RS08465	COG0049	tRNA binding
GPY10_RS08475	COG2168	tRNA wobble position uridine thiolation
GPY10_RS08480	COG2923	Belongs to the DsrF TusC family
GPY10_RS08490	COG2964	Protein conserved in bacteria
GPY10_RS08495	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY10_RS08510	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GPY10_RS08515	COG0330	HflC and HflK could
GPY10_RS08520	COG0330	HflC and HflK could
GPY10_RS08525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPY10_RS08530	COG1923	regulation of RNA biosynthetic process
GPY10_RS08535	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPY10_RS08540	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPY10_RS08550	COG0802	atpase or kinase
GPY10_RS08555	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPY10_RS08610	COG1162	GTPase activity
GPY10_RS08615	COG0688	phosphatidylethanolamine metabolic process
GPY10_RS08635	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPY10_RS08640	COG4942	peptidase
GPY10_RS08665	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GPY10_RS08670	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPY10_RS08675	COG0085	RNA polymerase activity
GPY10_RS08685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPY10_RS08690	COG0081	regulation of translation
GPY10_RS08695	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPY10_RS08700	COG0250	Participates in transcription elongation, termination and antitermination
GPY10_RS08705	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY10_RS08735	COG1072	(Pantothenic acid kinase))
GPY10_RS08745	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GPY10_RS08755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPY10_RS08820	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GPY10_RS08830	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPY10_RS08835	COG3118	belongs to the thioredoxin family
GPY10_RS08840	COG0513	Belongs to the DEAD box helicase family
GPY10_RS08845	COG0248	Ppx GppA phosphatase
GPY10_RS08850	COG2198	Histidine kinase
GPY10_RS08850	COG2205	protein histidine kinase activity
GPY10_RS08850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY10_RS08850	COG0784	Response regulator, receiver
GPY10_RS08855	COG2814	Major facilitator Superfamily
GPY10_RS08870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY10_RS08875	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GPY10_RS08880	COG0511	ligase activity, forming carbon-carbon bonds
GPY10_RS08885	COG0439	Biotin carboxylase
GPY10_RS08890	COG2264	protein methyltransferase activity
GPY10_RS08895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY10_RS08900	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GPY10_RS08905	COG0840	transmembrane signaling receptor activity
GPY10_RS08910	COG0789	Transcriptional regulator
GPY10_RS08920	COG0138	bifunctional purine biosynthesis protein purh
GPY10_RS08925	COG0151	Belongs to the GarS family
GPY10_RS08935	COG0776	regulation of translation
GPY10_RS08940	COG1253	flavin adenine dinucleotide binding
GPY10_RS08945	COG0668	transmembrane transport
GPY10_RS08950	COG3068	Protein conserved in bacteria
GPY10_RS08955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY10_RS08960	COG1573	uracil-dna glycosylase
GPY10_RS08965	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GPY10_RS08980	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPY10_RS09010	COG0367	asparagine synthase
GPY10_RS09040	COG2089	acid synthase
GPY10_RS09050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY10_RS09060	COG1560	Kdo2-lipid A biosynthetic process
GPY10_RS09075	COG0859	PFAM glycosyl transferase family 9
GPY10_RS09080	COG0859	PFAM glycosyl transferase family 9
GPY10_RS09085	COG1519	Transferase
GPY10_RS09090	COG0438	transferase activity, transferring glycosyl groups
GPY10_RS09100	COG0859	PFAM glycosyl transferase family 9
GPY10_RS09105	COG0463	Glycosyl transferase, family 2
GPY10_RS09110	COG0438	transferase activity, transferring glycosyl groups
GPY10_RS09115	COG0438	transferase activity, transferring glycosyl groups
GPY10_RS09120	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPY10_RS09135	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GPY10_RS09145	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GPY10_RS09165	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPY10_RS09170	COG1309	transcriptional regulator
GPY10_RS09175	COG1560	Kdo2-lipid A biosynthetic process
GPY10_RS09180	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPY10_RS09185	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GPY10_RS09190	COG1561	YicC-like family, N-terminal region
GPY10_RS09210	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GPY10_RS09215	COG1120	ATPase activity
GPY10_RS09220	COG1132	(ABC) transporter
GPY10_RS09235	COG0514	ATP-dependent DNA helicase (RecQ)
GPY10_RS09240	COG2962	Rard protein
GPY10_RS09250	COG1280	lysine exporter protein (LysE YggA)
GPY10_RS09255	COG0405	Gamma-glutamyltransferase
GPY10_RS09260	COG0210	DNA helicase
GPY10_RS09295	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GPY10_RS09300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY10_RS09315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY10_RS09320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY10_RS09330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY10_RS09340	COG0747	negative chemotaxis
GPY10_RS09345	COG4172	Belongs to the ABC transporter superfamily
GPY10_RS09380	COG0210	DNA helicase
GPY10_RS09390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY10_RS09395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY10_RS09400	COG2960	long-chain fatty acid transporting porin activity
GPY10_RS09410	COG0583	DNA-binding transcription factor activity
GPY10_RS09435	COG0582	viral genome integration into host DNA
GPY10_RS09510	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPY10_RS09520	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPY10_RS09525	COG0408	coproporphyrinogen oxidase activity
GPY10_RS09540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPY10_RS09545	COG0551	DNA topoisomerase type I activity
GPY10_RS09550	COG2922	Belongs to the Smg family
GPY10_RS09560	COG1652	LysM domain
GPY10_RS09565	COG0242	peptide deformylase activity
GPY10_RS09575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPY10_RS09575	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPY10_RS09580	COG0569	domain protein
GPY10_RS09585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY10_RS09595	COG1272	protein, Hemolysin III
GPY10_RS09600	COG4326	sporulation control protein
GPY10_RS09610	COG3084	Protein conserved in bacteria
GPY10_RS09625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY10_RS09630	COG0204	Acyl-transferase
GPY10_RS09645	COG3978	acetolactate synthase activity
GPY10_RS09650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPY10_RS09665	COG0604	alcohol dehydrogenase
GPY10_RS09690	COG2119	membrane
GPY10_RS09695	COG0752	glycyl-tRNA synthetase alpha subunit
GPY10_RS09700	COG0751	glycine-tRNA ligase activity
GPY10_RS09705	COG3977	Valine--pyruvate aminotransferase
GPY10_RS09710	COG0071	Belongs to the small heat shock protein (HSP20) family
GPY10_RS09720	COG0187	DNA topoisomerase II activity
GPY10_RS09730	COG0592	DNA-directed DNA polymerase activity
GPY10_RS09735	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPY10_RS09750	COG1126	abc transporter atp-binding protein
GPY10_RS09755	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GPY10_RS09765	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GPY10_RS09770	COG0706	membrane insertase activity
GPY10_RS09775	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPY10_RS09780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY10_RS09785	COG0445	tRNA wobble uridine modification
GPY10_RS09790	COG0357	Ribosomal RNA small subunit methyltransferase G
GPY10_RS09795	COG1192	Involved in chromosome partitioning
GPY10_RS09800	COG1475	DNA binding
GPY10_RS09805	COG3312	ion transport
GPY10_RS09810	COG0356	it plays a direct role in the translocation of protons across the membrane
GPY10_RS09820	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPY10_RS09825	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPY10_RS09835	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPY10_RS09840	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPY10_RS09845	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GPY10_RS09855	COG0765	amino acid transport
GPY10_RS09860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY10_RS09865	COG2814	Major facilitator Superfamily
GPY10_RS09870	COG0583	DNA-binding transcription factor activity
GPY10_RS09875	COG0183	Belongs to the thiolase family
GPY10_RS09885	COG1739	Uncharacterized protein family UPF0029
GPY10_RS09890	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY10_RS10010	COG2132	Multicopper oxidase
GPY10_RS10015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPY10_RS10020	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GPY10_RS10025	COG0352	thiamine-phosphate diphosphorylase activity
GPY10_RS10030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY10_RS10035	COG2104	thiamine diphosphate biosynthetic process
GPY10_RS10035	COG2022	thiamine diphosphate biosynthetic process
GPY10_RS10050	COG0517	IMP dehydrogenase activity
GPY10_RS10050	COG4175	Glycine betaine
GPY10_RS10080	COG0006	proline dipeptidase activity
GPY10_RS10080	COG0006	proline dipeptidase activity
GPY10_RS10100	COG1522	sequence-specific DNA binding
GPY10_RS10110	COG0742	ribosomal rna small subunit methyltransferase
GPY10_RS10125	COG0589	response to stress
GPY10_RS10130	COG1528	Iron-storage protein
GPY10_RS10140	COG2081	HI0933 family
GPY10_RS10145	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPY10_RS10150	COG1129	ABC transporter
GPY10_RS10155	COG1879	ABC-type sugar transport system periplasmic component
GPY10_RS10160	COG1069	ribulokinase activity
GPY10_RS10165	COG0235	Class ii aldolase
GPY10_RS10170	COG2160	L-arabinose isomerase activity
GPY10_RS10195	COG1322	Protein conserved in bacteria
GPY10_RS10200	COG2226	methyltransferase
GPY10_RS10205	COG3165	ubiquinone biosynthetic process from chorismate
GPY10_RS10210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GPY10_RS10220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPY10_RS10225	COG0805	protein transport
GPY10_RS10230	COG0084	hydrolase, TatD family'
GPY10_RS10240	COG0456	acetyltransferase
GPY10_RS10245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY10_RS10245	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY10_RS10250	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GPY10_RS10280	COG3071	HemY protein
GPY10_RS10285	COG2959	enzyme of heme biosynthesis
GPY10_RS10300	COG3072	Adenylate cyclase
GPY10_RS10315	COG0019	diaminopimelate decarboxylase activity
GPY10_RS10320	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPY10_RS10330	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GPY10_RS10335	COG1011	Hydrolase
GPY10_RS10340	COG3287	FIST C domain
GPY10_RS10340	COG2200	EAL domain
GPY10_RS10340	COG2199	diguanylate cyclase activity
GPY10_RS10360	COG0561	phosphatase activity
GPY10_RS10365	COG2267	carboxylic ester hydrolase activity
GPY10_RS10370	COG1280	lysine exporter protein (LysE YggA)
GPY10_RS10375	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY10_RS10380	COG0640	Transcriptional regulator
GPY10_RS10385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY10_RS10400	COG0783	Belongs to the Dps family
GPY10_RS10430	COG2095	MarC family integral membrane protein
GPY10_RS10440	COG0742	ribosomal rna small subunit methyltransferase
GPY10_RS10445	COG0552	protein localization to endoplasmic reticulum
GPY10_RS10450	COG2884	Cell division ATP-binding protein ftsE
GPY10_RS10455	COG2177	Part of the ABC transporter FtsEX involved in
GPY10_RS10460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPY10_RS10470	COG0705	Rhomboid family
GPY10_RS10475	COG1580	Controls the rotational direction of flagella during chemotaxis
GPY10_RS10485	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GPY10_RS10490	COG2937	Belongs to the GPAT DAPAT family
GPY10_RS10495	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPY10_RS10500	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPY10_RS10510	COG0534	Mate efflux family protein
GPY10_RS10530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY10_RS10545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GPY10_RS10605	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPY10_RS10615	COG2204	response regulator
GPY10_RS10620	COG3852	Histidine kinase
GPY10_RS10630	COG0174	glutamine synthetase
GPY10_RS10655	COG1490	D-aminoacyl-tRNA deacylase activity
GPY10_RS10660	COG0456	acetyltransferase
GPY10_RS10665	COG2982	Protein involved in outer membrane biogenesis
GPY10_RS10670	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GPY10_RS10675	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPY10_RS10680	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GPY10_RS10685	COG3031	protein transport across the cell outer membrane
GPY10_RS10695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY10_RS10705	COG2165	general secretion pathway protein
GPY10_RS10710	COG2165	general secretion pathway protein
GPY10_RS10715	COG2165	general secretion pathway protein
GPY10_RS10720	COG4795	General secretion pathway protein
GPY10_RS10725	COG3156	type II secretion system protein K
GPY10_RS10730	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPY10_RS10735	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPY10_RS10745	COG1218	3'(2'),5'-bisphosphate nucleotidase
GPY10_RS10755	COG0316	Belongs to the HesB IscA family
GPY10_RS10755	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GPY10_RS10760	COG1040	competence protein
GPY10_RS10775	COG2183	response to ionizing radiation
GPY10_RS10785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY10_RS10790	COG1609	Transcriptional regulator
GPY10_RS10795	COG0129	dihydroxy-acid dehydratase activity
GPY10_RS10800	COG3265	gluconokinase activity
GPY10_RS10805	COG2610	gluconate transmembrane transporter activity
GPY10_RS10810	COG0800	Aldolase
GPY10_RS10815	COG0745	RESPONSE REGULATOR receiver
GPY10_RS10820	COG2205	protein histidine kinase activity
GPY10_RS10825	COG2233	PERMEase
GPY10_RS10830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPY10_RS10835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY10_RS10840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY10_RS10850	COG0194	GDP metabolic process
GPY10_RS10855	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPY10_RS10860	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY10_RS10870	COG3263	regulation of cellular component size
GPY10_RS10880	COG4232	protein-disulfide reductase activity
GPY10_RS10890	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GPY10_RS10895	COG0540	Belongs to the ATCase OTCase family
GPY10_RS10900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPY10_RS10915	COG1288	antiporter activity
GPY10_RS10925	COG1027	Aspartate ammonia-lyase
GPY10_RS10935	COG3030	protein affecting phage T7 exclusion by the F plasmid
GPY10_RS10950	COG2205	protein histidine kinase activity
GPY10_RS10955	COG0745	RESPONSE REGULATOR receiver
GPY10_RS10965	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPY10_RS10970	COG0205	6-phosphofructokinase activity
GPY10_RS10975	COG1494	fructose-1,6-bisphosphatase
GPY10_RS10985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPY10_RS10990	COG0460	homoserine dehydrogenase
GPY10_RS10990	COG0527	aspartate kinase activity
GPY10_RS10995	COG0626	cystathionine gamma-synthase activity
GPY10_RS11005	COG0281	malic enzyme
GPY10_RS11010	COG0254	rRNA binding
GPY10_RS11020	COG1609	Transcriptional regulator
GPY10_RS11030	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GPY10_RS11035	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GPY10_RS11040	COG1575	Belongs to the MenA family. Type 1 subfamily
GPY10_RS11045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPY10_RS11055	COG0149	triose-phosphate isomerase activity
GPY10_RS11080	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPY10_RS11085	COG0459	protein refolding
GPY10_RS11090	COG1119	ATPase activity
GPY10_RS11100	COG1285	pathogenesis
GPY10_RS11105	COG1509	lysine 2,3-aminomutase activity
GPY10_RS11110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPY10_RS11115	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPY10_RS11120	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPY10_RS11125	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPY10_RS11130	COG1053	succinate dehydrogenase
GPY10_RS11135	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GPY10_RS11140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY10_RS11145	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GPY10_RS11150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GPY10_RS11155	COG1045	serine acetyltransferase
GPY10_RS11160	COG1695	Transcriptional regulator
GPY10_RS11165	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GPY10_RS11170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY10_RS11175	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPY10_RS11180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPY10_RS11190	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPY10_RS11190	COG0165	Argininosuccinate lyase
GPY10_RS11200	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY10_RS11200	COG0678	peroxiredoxin activity
GPY10_RS11210	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GPY10_RS11245	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPY10_RS11255	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GPY10_RS11260	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPY10_RS11270	COG0180	Tryptophanyl-tRNA synthetase
GPY10_RS11280	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPY10_RS11290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPY10_RS11300	COG1012	belongs to the aldehyde dehydrogenase family
GPY10_RS11310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY10_RS11315	COG3954	Phosphoribulokinase
GPY10_RS11340	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPY10_RS11350	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GPY10_RS11355	COG1047	Peptidyl-prolyl cis-trans
GPY10_RS11365	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPY10_RS11370	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GPY10_RS11375	COG3083	sulfuric ester hydrolase activity
GPY10_RS11380	COG0557	exoribonuclease II activity
GPY10_RS11385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY10_RS11390	COG0051	transcription antitermination factor activity, RNA binding
GPY10_RS11395	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPY10_RS11400	COG0088	Forms part of the polypeptide exit tunnel
GPY10_RS11405	COG0089	rRNA binding
GPY10_RS11415	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPY10_RS11420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPY10_RS11435	COG0255	Belongs to the universal ribosomal protein uL29 family
GPY10_RS11445	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPY10_RS11450	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPY10_RS11455	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPY10_RS11460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPY10_RS11465	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPY10_RS11470	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPY10_RS11475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPY10_RS11485	COG1841	ribosomal large subunit assembly
GPY10_RS11495	COG0201	protein transport
GPY10_RS11510	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPY10_RS11515	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPY10_RS11520	COG0202	RNA polymerase activity
GPY10_RS11525	COG0203	ribosomal protein L17
GPY10_RS11535	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY10_RS11540	COG3061	Opacity-associated protein A
GPY10_RS11545	COG0697	spore germination
GPY10_RS11550	COG2153	protein acetylation
GPY10_RS11555	COG0513	Belongs to the DEAD box helicase family
GPY10_RS11565	COG0737	Belongs to the 5'-nucleotidase family
GPY10_RS11570	COG1648	precorrin-2 dehydrogenase activity
GPY10_RS11570	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPY10_RS11575	COG0175	sulfate reduction
GPY10_RS11580	COG2895	sulfate adenylyltransferase (ATP) activity
GPY10_RS11585	COG0471	metal ion transport
GPY10_RS11585	COG0490	domain, Protein
GPY10_RS11590	COG0529	Catalyzes the synthesis of activated sulfate
GPY10_RS11610	COG0577	efflux transmembrane transporter activity
GPY10_RS11610	COG1136	(ABC) transporter
GPY10_RS11625	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GPY10_RS11630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY10_RS11635	COG0729	surface antigen
GPY10_RS11645	COG2105	PFAM AIG2 family protein
GPY10_RS11650	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GPY10_RS11655	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GPY10_RS11660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPY10_RS11665	COG0163	prenyltransferase activity
GPY10_RS11670	COG4143	(ABC) transporter
GPY10_RS11680	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GPY10_RS11685	COG3028	Belongs to the UPF0307 family
GPY10_RS11690	COG0312	modulator of DNA gyrase
GPY10_RS11695	COG2239	Acts as a magnesium transporter
GPY10_RS11700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY10_RS11710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY10_RS11715	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY10_RS11725	COG1137	ATPase activity
GPY10_RS11730	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GPY10_RS11740	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GPY10_RS11755	COG1127	ABC transporter
GPY10_RS11760	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GPY10_RS11765	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPY10_RS11770	COG2854	intermembrane phospholipid transfer
GPY10_RS11775	COG3113	response to antibiotic
GPY10_RS11780	COG5007	Belongs to the BolA IbaG family
GPY10_RS11785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPY10_RS11795	COG0251	oxidation-reduction process
GPY10_RS11800	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GPY10_RS11805	COG0540	Belongs to the ATCase OTCase family
GPY10_RS11810	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPY10_RS11815	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GPY10_RS11820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GPY10_RS11830	COG0564	pseudouridine synthase activity
GPY10_RS11835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY10_RS11840	COG0525	valine-tRNA ligase activity
GPY10_RS11855	COG0795	lipopolysaccharide-transporting ATPase activity
GPY10_RS11860	COG0795	lipopolysaccharide-transporting ATPase activity
GPY10_RS11870	COG3706	GGDEF domain
GPY10_RS11945	COG2916	Histone family protein nucleoid-structuring protein H-NS
GPY10_RS12020	COG2203	Gaf domain
GPY10_RS12020	COG2200	EAL domain
GPY10_RS12020	COG2199	diguanylate cyclase activity
GPY10_RS12080	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPY10_RS12085	COG0473	3-isopropylmalate dehydrogenase activity
GPY10_RS12110	COG0583	DNA-binding transcription factor activity
GPY10_RS12115	COG1022	Amp-dependent synthetase and ligase
GPY10_RS12120	COG0028	Belongs to the TPP enzyme family
GPY10_RS12125	COG0440	acetolactate synthase activity
GPY10_RS12130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY10_RS12140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPY10_RS12150	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPY10_RS12160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY10_RS12165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY10_RS12180	COG0354	folic acid binding
GPY10_RS12185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GPY10_RS12195	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GPY10_RS12200	COG1595	DNA-templated transcription, initiation
GPY10_RS12220	COG0481	GTPase activity
GPY10_RS12225	COG0681	Belongs to the peptidase S26 family
GPY10_RS12230	COG0571	ribonuclease III activity
GPY10_RS12235	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPY10_RS12240	COG1381	Involved in DNA repair and RecF pathway recombination
GPY10_RS12245	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GPY10_RS12250	COG0736	holo-[acyl-carrier-protein] synthase activity
GPY10_RS12260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY10_RS12265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY10_RS12270	COG3956	TIGRFAM MazG family protein
GPY10_RS12275	COG0504	CTP synthase activity
GPY10_RS12280	COG0148	phosphopyruvate hydratase activity
GPY10_RS12285	COG0617	tRNA 3'-terminal CCA addition
GPY10_RS12290	COG3409	Peptidoglycan-binding domain 1 protein
GPY10_RS12290	COG3267	Type II secretory pathway component ExeA
GPY10_RS12300	COG4991	sh3 domain protein
GPY10_RS12305	COG0306	phosphate transporter
GPY10_RS12310	COG1392	Phosphate transport regulator
GPY10_RS12315	COG3025	triphosphatase activity
GPY10_RS12320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY10_RS12330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GPY10_RS12335	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GPY10_RS12335	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GPY10_RS12340	COG1538	Outer membrane efflux protein
GPY10_RS12345	COG0494	nUDIX hydrolase
GPY10_RS12350	COG3151	Protein conserved in bacteria
GPY10_RS12360	COG3150	esterase
GPY10_RS12365	COG0187	DNA topoisomerase II activity
GPY10_RS12370	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPY10_RS12375	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GPY10_RS12380	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GPY10_RS12395	COG1459	type II secretion system
GPY10_RS12400	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY10_RS12420	COG0716	FMN binding
GPY10_RS12425	COG4974	Belongs to the 'phage' integrase family
GPY10_RS12430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY10_RS12435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GPY10_RS12440	COG2186	Transcriptional regulator
GPY10_RS12445	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GPY10_RS12450	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY10_RS12455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY10_RS12475	COG1131	(ABC) transporter
GPY10_RS12485	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GPY10_RS12490	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GPY10_RS12495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY10_RS12505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY10_RS12510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY10_RS12515	COG1489	DNA binding
GPY10_RS12520	COG1643	Atp-dependent helicase
GPY10_RS12525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPY10_RS12530	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPY10_RS12535	COG1049	propionate catabolic process, 2-methylcitrate cycle
GPY10_RS12545	COG0347	Belongs to the P(II) protein family
GPY10_RS12550	COG0004	ammonium transporteR
GPY10_RS12555	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY10_RS12565	COG3842	ATPase activity
GPY10_RS12570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY10_RS12585	COG2971	BadF BadG BcrA BcrD
GPY10_RS12595	COG4608	Belongs to the ABC transporter superfamily
GPY10_RS12600	COG0444	Belongs to the ABC transporter superfamily
GPY10_RS12605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY10_RS12615	COG0747	negative chemotaxis
GPY10_RS12630	COG0628	permease
GPY10_RS12640	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GPY10_RS12645	COG0316	Belongs to the HesB IscA family
GPY10_RS12665	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPY10_RS12675	COG2239	Acts as a magnesium transporter
GPY10_RS12680	COG2027	D-alanyl-D-alanine carboxypeptidase
GPY10_RS12685	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPY10_RS12690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY10_RS12695	COG1534	Rna-binding protein
GPY10_RS12710	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPY10_RS12715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY10_RS12720	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY10_RS12735	COG0779	Required for maturation of 30S ribosomal subunits
GPY10_RS12740	COG0195	Participates in both transcription termination and antitermination
GPY10_RS12750	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPY10_RS12755	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPY10_RS12780	COG0534	Mate efflux family protein
GPY10_RS12825	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GPY10_RS12830	COG0513	Belongs to the DEAD box helicase family
GPY10_RS12850	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GPY10_RS12855	COG2204	response regulator
GPY10_RS12865	COG0667	Aldo Keto reductase
GPY10_RS12875	COG3066	DNA modification
GPY10_RS12880	COG0494	nUDIX hydrolase
GPY10_RS12890	COG0730	response to heat
GPY10_RS12900	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPY10_RS12905	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPY10_RS12910	COG0583	DNA-binding transcription factor activity
GPY10_RS12915	COG0640	Transcriptional regulator
GPY10_RS12930	COG0196	riboflavin kinase activity
GPY10_RS12935	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPY10_RS12940	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPY10_RS12945	COG1047	Peptidyl-prolyl cis-trans
GPY10_RS12950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GPY10_RS12955	COG1966	Carbon starvation protein
GPY10_RS12970	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPY10_RS12975	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GPY10_RS12985	COG3279	Response regulator of the LytR AlgR family
GPY10_RS12990	COG3275	phosphorelay sensor kinase activity
GPY10_RS12995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY10_RS13000	COG0287	Prephenate dehydrogenase
GPY10_RS13000	COG1605	Chorismate mutase
GPY10_RS13010	COG0488	(ABC) transporter
GPY10_RS13025	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GPY10_RS13030	COG5001	Diguanylate cyclase
GPY10_RS13035	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY10_RS13040	COG1605	Chorismate mutase
GPY10_RS13040	COG0077	Prephenate dehydratase
GPY10_RS13045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY10_RS13050	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GPY10_RS13055	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY10_RS13060	COG0564	pseudouridine synthase activity
GPY10_RS13070	COG0542	response to heat
GPY10_RS13080	COG0590	tRNA wobble adenosine to inosine editing
GPY10_RS13085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GPY10_RS13170	COG0271	Belongs to the BolA IbaG family
GPY10_RS13175	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY10_RS13190	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY10_RS13195	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY10_RS13200	COG2871	sodium ion transport
GPY10_RS13205	COG1477	protein flavinylation
GPY10_RS13220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPY10_RS13230	COG3706	GGDEF domain
GPY10_RS13230	COG2203	Gaf domain
GPY10_RS13230	COG5001	Diguanylate cyclase
GPY10_RS13230	COG4251	negative regulation of phosphorylation
GPY10_RS13235	COG0733	neurotransmitter:sodium symporter activity
GPY10_RS13245	COG0189	ligase activity
GPY10_RS13250	COG4067	protein conserved in archaea
GPY10_RS13250	COG0189	ligase activity
GPY10_RS13255	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY10_RS13260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY10_RS13265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPY10_RS13275	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPY10_RS13290	COG2252	PERMEase
GPY10_RS13295	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GPY10_RS13310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPY10_RS13315	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPY10_RS13320	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPY10_RS13325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY10_RS13325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY10_RS13345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPY10_RS13350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GPY10_RS13355	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GPY10_RS13365	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GPY10_RS13370	COG0024	Methionine aminopeptidase
GPY10_RS13395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPY10_RS13400	COG0575	Belongs to the CDS family
GPY10_RS13405	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GPY10_RS13410	COG0750	zinc metalloprotease
GPY10_RS13420	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GPY10_RS13425	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY10_RS13430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY10_RS13455	COG0825	malonyl-CoA metabolic process
GPY10_RS13460	COG0037	tRNA processing
GPY10_RS13470	COG0347	Belongs to the P(II) protein family
GPY10_RS13485	COG0741	lytic transglycosylase activity
GPY10_RS13485	COG1388	LysM domain
GPY10_RS13495	COG2226	methyltransferase
GPY10_RS13500	COG0328	RNA-DNA hybrid ribonuclease activity
GPY10_RS13505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPY10_RS13515	COG1960	acyl-CoA dehydrogenase activity
GPY10_RS13520	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPY10_RS13530	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPY10_RS13535	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GPY10_RS13540	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPY10_RS13545	COG1187	pseudouridine synthase activity
GPY10_RS13550	COG2840	Smr protein MutS2
GPY10_RS13580	COG2217	Heavy metal translocating P-type atpase
GPY10_RS13580	COG2608	mercury ion transmembrane transporter activity
GPY10_RS13585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY10_RS13630	COG4695	Portal protein
GPY10_RS13660	COG2747	anti-sigma28 factor FlgM
GPY10_RS13670	COG0835	chemotaxis
GPY10_RS13670	COG0784	Response regulator, receiver
GPY10_RS13675	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPY10_RS13680	COG1815	bacterial-type flagellum-dependent cell motility
GPY10_RS13685	COG1558	bacterial-type flagellum-dependent cell motility
GPY10_RS13690	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPY10_RS13695	COG1749	Flagellar hook protein flgE
GPY10_RS13700	COG4787	bacterial-type flagellum-dependent cell motility
GPY10_RS13705	COG4786	Flagellar basal body rod
GPY10_RS13710	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GPY10_RS13715	COG1706	bacterial-type flagellum-dependent cell motility
GPY10_RS13720	COG3951	Flagellar rod assembly protein muramidase FlgJ
GPY10_RS13720	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPY10_RS13735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY10_RS13835	COG0193	aminoacyl-tRNA hydrolase activity
GPY10_RS13840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPY10_RS13850	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GPY10_RS13855	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPY10_RS13860	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPY10_RS13865	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY10_RS13870	COG3094	Invasion gene expression up-regulator, SirB
GPY10_RS13875	COG2912	Transglutaminase-like superfamily
GPY10_RS13885	COG0737	Belongs to the 5'-nucleotidase family
GPY10_RS13915	COG1393	Belongs to the ArsC family
GPY10_RS13920	COG4783	chaperone-mediated protein folding
GPY10_RS13940	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPY10_RS13945	COG2716	regulation of RNA biosynthetic process
GPY10_RS13950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPY10_RS13955	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GPY10_RS13970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY10_RS13975	COG1393	Belongs to the ArsC family
GPY10_RS13985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPY10_RS13990	COG1085	galactose-1-phosphate uridylyltransferase
GPY10_RS13995	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPY10_RS14015	COG2837	iron assimilation
GPY10_RS14025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY10_RS14030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY10_RS14035	COG1334	flagellar protein FlaG
GPY10_RS14040	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPY10_RS14050	COG1516	flagellar protein fliS
GPY10_RS14055	COG2204	response regulator
GPY10_RS14060	COG4191	Histidine kinase
GPY10_RS14065	COG2204	response regulator
GPY10_RS14070	COG1677	Flagellar hook-basal body complex protein FliE
GPY10_RS14080	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY10_RS14130	COG1987	bacterial-type flagellum assembly
GPY10_RS14150	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY10_RS14155	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPY10_RS14160	COG0583	DNA-binding transcription factor activity
GPY10_RS14165	COG1028	Short-chain dehydrogenase reductase Sdr
GPY10_RS14170	COG2860	membrane
GPY10_RS14175	COG3101	peptidyl-lysine hydroxylation
GPY10_RS14195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPY10_RS14200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY10_RS14210	COG0735	belongs to the Fur family
GPY10_RS14225	COG1380	Effector of murein hydrolase LrgA
GPY10_RS14230	COG1346	cytolysis
GPY10_RS14245	COG0596	Alpha beta hydrolase
GPY10_RS14250	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GPY10_RS14255	COG0033	Phosphoglucomutase
GPY10_RS14265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPY10_RS14280	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GPY10_RS14295	COG0567	Dehydrogenase, E1 component
GPY10_RS14300	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY10_RS14315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPY10_RS14320	COG1121	(ABC) transporter
GPY10_RS14325	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GPY10_RS14335	COG1918	ferrous iron import across plasma membrane
GPY10_RS14360	COG3102	Protein conserved in bacteria
GPY10_RS14370	COG2062	phosphohistidine phosphatase, SixA
GPY10_RS14385	COG0455	bacterial-type flagellum organization
GPY10_RS14400	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GPY10_RS14405	COG2198	Histidine kinase
GPY10_RS14405	COG0643	Histidine kinase
GPY10_RS14410	COG2201	protein-glutamate methylesterase activity
GPY10_RS14415	COG1192	Involved in chromosome partitioning
GPY10_RS14425	COG0835	chemotaxis
GPY10_RS14435	COG4133	protoheme IX ABC transporter activity
GPY10_RS14445	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY10_RS14450	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY10_RS14455	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GPY10_RS14460	COG1138	Cytochrome C-type biogenesis protein
GPY10_RS14465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY10_RS14480	COG2853	Lipoprotein
GPY10_RS14500	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GPY10_RS14505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY10_RS14510	COG3384	dioxygenase
GPY10_RS14535	COG0667	Aldo Keto reductase
GPY10_RS14550	COG0583	DNA-binding transcription factor activity
GPY10_RS14555	COG2159	amidohydrolase
GPY10_RS14560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPY10_RS14600	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPY10_RS14615	COG0123	including yeast histone deacetylase and acetoin utilization protein
GPY10_RS14640	COG3083	sulfuric ester hydrolase activity
GPY10_RS14650	COG3081	Nucleoid-associated protein
GPY10_RS14660	COG1757	Na H antiporter
GPY10_RS14665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPY10_RS14670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY10_RS14675	COG2095	MarC family integral membrane protein
GPY10_RS14690	COG0659	secondary active sulfate transmembrane transporter activity
GPY10_RS14700	COG1530	ribonuclease E activity
GPY10_RS14705	COG0564	pseudouridine synthase activity
GPY10_RS14710	COG0424	maF-like protein
GPY10_RS14715	COG1399	metal-binding, possibly nucleic acid-binding protein
GPY10_RS14725	COG0416	fatty acid biosynthetic process
GPY10_RS14730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY10_RS14750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY10_RS14750	COG1017	nitric oxide dioxygenase activity
GPY10_RS14755	COG3706	GGDEF domain
GPY10_RS14765	COG1278	Cold shock
GPY10_RS14770	COG3036	rescue of stalled ribosome
GPY10_RS14790	COG0745	RESPONSE REGULATOR receiver
GPY10_RS14800	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPY10_RS14800	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GPY10_RS14805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY10_RS14830	COG0798	PFAM Bile acid sodium symporter
GPY10_RS14870	COG4964	Belongs to the GSP D family
GPY10_RS14925	COG0840	transmembrane signaling receptor activity
GPY10_RS14940	COG4533	DNA binding
GPY10_RS14945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY10_RS14950	COG3835	regulator
GPY10_RS14955	COG2610	gluconate transmembrane transporter activity
GPY10_RS14960	COG1929	Belongs to the glycerate kinase type-1 family
GPY10_RS14970	COG1473	amidohydrolase
GPY10_RS14985	COG0531	amino acid
GPY10_RS14990	COG0646	methionine synthase
GPY10_RS14990	COG1410	methionine synthase
GPY10_RS15005	COG0583	DNA-binding transcription factor activity
GPY10_RS15020	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPY10_RS15025	COG0363	glucosamine-6-phosphate deaminase activity
GPY10_RS15030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPY10_RS15035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPY10_RS15045	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPY10_RS15065	COG0346	lactoylglutathione lyase activity
GPY10_RS15075	COG3284	Transcriptional regulator
GPY10_RS15080	COG1012	belongs to the aldehyde dehydrogenase family
GPY10_RS15085	COG0156	8-amino-7-oxononanoate synthase activity
GPY10_RS15090	COG1063	alcohol dehydrogenase
GPY10_RS15110	COG1278	Cold shock
GPY10_RS15120	COG0582	viral genome integration into host DNA
GPY10_RS15180	COG1403	HNH endonuclease
GPY10_RS15220	COG3772	lysozyme
GPY10_RS15400	COG0583	DNA-binding transcription factor activity
GPY10_RS15405	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPY10_RS15415	COG2084	Dehydrogenase
GPY10_RS15420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY10_RS15430	COG0242	peptide deformylase activity
GPY10_RS15440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPY10_RS15455	COG2246	polysaccharide biosynthetic process
GPY10_RS15470	COG1132	(ABC) transporter
GPY10_RS15475	COG1132	(ABC) transporter
GPY10_RS15485	COG2267	carboxylic ester hydrolase activity
GPY10_RS15490	COG0583	DNA-binding transcription factor activity
GPY10_RS15500	COG0251	oxidation-reduction process
GPY10_RS15510	COG0071	Belongs to the small heat shock protein (HSP20) family
GPY10_RS15515	COG3047	cAMP biosynthetic process
GPY10_RS15520	COG3227	Zinc metalloprotease (Elastase)
GPY10_RS15525	COG0366	Alpha amylase catalytic
GPY10_RS15540	COG4989	oxidoreductase activity
GPY10_RS15545	COG3275	phosphorelay sensor kinase activity
GPY10_RS15550	COG3279	Response regulator of the LytR AlgR family
GPY10_RS15555	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPY10_RS15575	COG0840	transmembrane signaling receptor activity
GPY10_RS15585	COG2814	Major facilitator Superfamily
GPY10_RS15605	COG1522	sequence-specific DNA binding
GPY10_RS15615	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPY10_RS15620	COG5380	lipid catabolic process
GPY10_RS15625	COG4412	M6 family metalloprotease domain protein
GPY10_RS15625	COG3291	Pkd domain containing protein
GPY10_RS15645	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY10_RS15655	COG4604	ABC transporter, ATP-binding protein
GPY10_RS15660	COG1609	Transcriptional regulator
GPY10_RS15660	COG2207	Transcriptional regulator
GPY10_RS15675	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPY10_RS15690	COG1051	belongs to the nudix hydrolase family
GPY10_RS15735	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPY10_RS15740	COG1454	alcohol dehydrogenase
GPY10_RS15745	COG2207	Transcriptional regulator
GPY10_RS15745	COG1609	Transcriptional regulator
GPY10_RS15775	COG3634	alkyl hydroperoxide reductase activity
GPY10_RS15780	COG0450	alkyl hydroperoxide reductase
GPY10_RS15795	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPY10_RS15800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GPY10_RS15805	COG1960	acyl-CoA dehydrogenase activity
GPY10_RS15815	COG0183	Belongs to the thiolase family
GPY10_RS15825	COG1960	acyl-CoA dehydrogenase activity
GPY10_RS15830	COG1024	Enoyl-CoA hydratase
GPY10_RS15835	COG1024	Enoyl-CoA hydratase
GPY10_RS15845	COG1028	Short-chain dehydrogenase reductase Sdr
GPY10_RS15855	COG1028	Short-chain dehydrogenase reductase Sdr
GPY10_RS15870	COG0653	protein targeting
GPY10_RS15885	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPY10_RS15905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY10_RS15905	COG0512	Glutamine amidotransferase of anthranilate synthase
GPY10_RS15910	COG1464	Belongs to the NlpA lipoprotein family
GPY10_RS15930	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY10_RS15935	COG0573	inorganic phosphate transmembrane transporter activity
GPY10_RS15945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY10_RS15965	COG0625	glutathione transferase activity
GPY10_RS16020	COG2721	sulfolactate sulfo-lyase activity
GPY10_RS16035	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GPY10_RS16045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPY10_RS16055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY10_RS16090	COG1280	lysine exporter protein (LysE YggA)
GPY10_RS16095	COG0400	carboxylic ester hydrolase activity
GPY10_RS16100	COG0435	Glutathione S-transferase
GPY10_RS16105	COG0583	DNA-binding transcription factor activity
GPY10_RS16110	COG4145	pantothenate transmembrane transporter activity
GPY10_RS16135	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPY10_RS16150	COG0583	DNA-binding transcription factor activity
GPY10_RS16160	COG3217	Mosc domain protein beta barrel domain protein
GPY10_RS16160	COG0633	Ferredoxin
GPY10_RS16175	COG1595	DNA-templated transcription, initiation
GPY10_RS16195	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GPY10_RS16210	COG2198	Histidine kinase
GPY10_RS16210	COG2205	protein histidine kinase activity
GPY10_RS16210	COG0784	Response regulator, receiver
GPY10_RS16215	COG3437	response regulator, receiver
GPY10_RS16225	COG4172	Belongs to the ABC transporter superfamily
GPY10_RS16230	COG0747	negative chemotaxis
GPY10_RS16255	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GPY10_RS16265	COG3706	GGDEF domain
GPY10_RS16270	COG0110	maltose O-acetyltransferase activity
GPY10_RS16275	COG1349	DNA-binding transcription factor activity
GPY10_RS16285	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GPY10_RS16300	COG1132	(ABC) transporter
GPY10_RS16310	COG1538	Outer membrane efflux protein
GPY10_RS16340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY10_RS16350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY10_RS16350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY10_RS16350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY10_RS16355	COG2207	Transcriptional regulator
GPY10_RS16365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY10_RS16455	COG0583	DNA-binding transcription factor activity
GPY10_RS16465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY10_RS16475	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GPY10_RS16480	COG0513	Belongs to the DEAD box helicase family
GPY10_RS16485	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPY10_RS16525	COG4628	conserved protein (DUF2132)
GPY10_RS16535	COG1028	Short-chain dehydrogenase reductase Sdr
GPY10_RS16590	COG0789	Transcriptional regulator
GPY10_RS16595	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPY10_RS16655	COG0454	-acetyltransferase
GPY10_RS16665	COG1028	Short-chain dehydrogenase reductase Sdr
GPY10_RS16685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY10_RS16715	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPY10_RS16725	COG0494	nUDIX hydrolase
GPY10_RS16730	COG1280	lysine exporter protein (LysE YggA)
GPY10_RS16740	COG0456	acetyltransferase
GPY10_RS16745	COG4977	sequence-specific DNA binding
GPY10_RS16750	COG1335	isochorismatase
GPY10_RS16780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY10_RS16785	COG1309	transcriptional regulator
GPY10_RS16800	COG0583	DNA-binding transcription factor activity
GPY10_RS16820	COG0745	RESPONSE REGULATOR receiver
GPY10_RS16825	COG1280	lysine exporter protein (LysE YggA)
GPY10_RS16880	COG1328	CTP reductase activity
GPY10_RS16885	COG0602	queuosine metabolic process
GPY10_RS16895	COG0189	ligase activity
GPY10_RS16895	COG4067	protein conserved in archaea
GPY10_RS16900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY10_RS16900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY10_RS16900	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GPY10_RS16905	COG1105	Belongs to the carbohydrate kinase PfkB family
GPY10_RS16910	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY10_RS16910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY10_RS16915	COG1609	Transcriptional regulator
GPY10_RS16930	COG0784	Response regulator, receiver
GPY10_RS16930	COG2205	protein histidine kinase activity
GPY10_RS16935	COG0156	8-amino-7-oxononanoate synthase activity
GPY10_RS16945	COG0038	chloride channel
GPY10_RS16950	COG0523	cobalamin synthesis protein
GPY10_RS16960	COG2207	Transcriptional regulator
GPY10_RS16970	COG3437	response regulator, receiver
GPY10_RS16975	COG0784	Response regulator, receiver
GPY10_RS16975	COG2205	protein histidine kinase activity
GPY10_RS16975	COG5002	protein histidine kinase activity
GPY10_RS16985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY10_RS16985	COG0543	2 iron, 2 sulfur cluster binding
GPY10_RS16990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPY10_RS16995	COG0243	molybdopterin cofactor binding
GPY10_RS17005	COG5001	Diguanylate cyclase
GPY10_RS17030	COG3038	cytochrome b561
GPY10_RS17035	COG2353	YceI-like domain
GPY10_RS17040	COG2116	formate transmembrane transporter activity
GPY10_RS17045	COG0583	DNA-binding transcription factor activity
GPY10_RS17055	COG3593	DNA synthesis involved in DNA repair
GPY10_RS17060	COG0737	Belongs to the 5'-nucleotidase family
GPY10_RS17065	COG0861	Integral membrane protein TerC family
GPY10_RS17075	COG2824	Alkylphosphonate utilization operon protein PhnA
GPY10_RS17080	COG0501	Belongs to the peptidase M48B family
GPY10_RS17085	COG2050	protein possibly involved in aromatic compounds catabolism
GPY10_RS17105	COG4771	TonB-dependent receptor
GPY10_RS17105	COG1629	transport
GPY10_RS17110	COG0583	DNA-binding transcription factor activity
GPY10_RS17115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY10_RS17115	COG0045	succinate-CoA ligase (ADP-forming) activity
GPY10_RS17115	COG1042	CoA-binding domain protein
GPY10_RS17125	COG1181	Belongs to the D-alanine--D-alanine ligase family
GPY10_RS17140	COG0023	Translation Initiation Factor
GPY10_RS17160	COG0745	RESPONSE REGULATOR receiver
GPY10_RS17170	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GPY10_RS17175	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GPY10_RS17190	COG0745	RESPONSE REGULATOR receiver
GPY10_RS17190	COG3706	GGDEF domain
GPY10_RS17200	COG3706	GGDEF domain
GPY10_RS17210	COG1309	transcriptional regulator
GPY10_RS17215	COG1129	ABC transporter
GPY10_RS17255	COG2351	hydroxyisourate hydrolase activity
GPY10_RS17260	COG0402	S-adenosylhomocysteine deaminase activity
GPY10_RS17280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPY10_RS17310	COG0765	amino acid transport
GPY10_RS17325	COG1953	Uracil, thiamine, allantoin
GPY10_RS17345	COG2233	PERMEase
GPY10_RS17360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY10_RS17390	COG3710	Transcriptional regulator
GPY10_RS17410	COG2814	Major facilitator Superfamily
GPY10_RS17440	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GPY10_RS17460	COG2207	Transcriptional regulator
GPY10_RS17495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY10_RS17535	COG2501	S4 domain
GPY10_RS17545	COG3706	GGDEF domain
GPY10_RS17575	COG4172	Belongs to the ABC transporter superfamily
GPY10_RS17580	COG4239	(ABC) transporter, permease
GPY10_RS17585	COG4174	ABC transporter (Permease)
GPY10_RS17590	COG4166	transmembrane transport
GPY10_RS17615	COG2866	Carboxypeptidase
GPY10_RS17635	COG3842	ATPase activity
GPY10_RS17645	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPY10_RS17655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY10_RS17665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY10_RS17670	COG1011	Hydrolase
GPY10_RS17680	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GPY10_RS17685	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GPY10_RS17690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY10_RS17690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY10_RS17695	COG2207	Transcriptional regulator
GPY10_RS17700	COG4303	Ethanolamine ammonia lyase large subunit
GPY10_RS17710	COG0531	amino acid
GPY10_RS17715	COG0302	gtp cyclohydrolase
GPY10_RS17725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY10_RS17730	COG2897	thiosulfate sulfurtransferase activity
GPY10_RS17745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPY10_RS17750	COG0840	transmembrane signaling receptor activity
GPY10_RS17765	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY10_RS17770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY10_RS17775	COG0840	transmembrane signaling receptor activity
GPY10_RS17780	COG2814	Major facilitator Superfamily
GPY10_RS17795	COG3069	C4-dicarboxylate transmembrane transporter activity
GPY10_RS17800	COG2197	response regulator
GPY10_RS17805	COG3850	Histidine kinase
GPY10_RS17820	COG0243	molybdopterin cofactor binding
GPY10_RS17860	COG0183	Belongs to the thiolase family
GPY10_RS17870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY10_RS17875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY10_RS17895	COG3706	GGDEF domain
GPY10_RS17900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPY10_RS17915	COG2207	Transcriptional regulator
GPY10_RS17920	COG1979	alcohol dehydrogenase
GPY10_RS17940	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY10_RS17945	COG2271	Major facilitator Superfamily
GPY10_RS18020	COG1289	transmembrane transporter activity
GPY10_RS18035	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GPY10_RS18040	COG4149	molybdate abc transporter
GPY10_RS18045	COG0725	ABC transporter, periplasmic molybdate-binding protein
GPY10_RS18050	COG1492	cobalamin metabolic process
GPY10_RS18070	COG5002	protein histidine kinase activity
GPY10_RS18070	COG0784	Response regulator, receiver
GPY10_RS18075	COG1879	ABC-type sugar transport system periplasmic component
GPY10_RS18085	COG2827	Endonuclease containing a URI domain
GPY10_RS18120	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPY10_RS18125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPY10_RS18130	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPY10_RS18135	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GPY10_RS18140	COG0247	lactate metabolic process
GPY10_RS18160	COG0438	transferase activity, transferring glycosyl groups
GPY10_RS18185	COG1596	polysaccharide export
GPY10_RS18195	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPY10_RS18210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY10_RS18215	COG3118	belongs to the thioredoxin family
GPY10_RS18220	COG2814	Major facilitator Superfamily
GPY10_RS18250	COG2116	formate transmembrane transporter activity
GPY10_RS18255	COG2146	nitrite reductase [NAD(P)H] activity
GPY10_RS18260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPY10_RS18295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY10_RS18330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY10_RS18335	COG1120	ATPase activity
GPY10_RS18345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY10_RS18355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY10_RS18370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY10_RS18375	COG2390	Transcriptional regulator
GPY10_RS18385	COG2186	Transcriptional regulator
GPY10_RS18395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GPY10_RS18410	COG0246	Mannitol dehydrogenase
GPY10_RS18415	COG1904	glucuronate isomerase
GPY10_RS18420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY10_RS18425	COG0800	Aldolase
GPY10_RS18430	COG1294	oxidase, subunit
GPY10_RS18435	COG1271	oxidase subunit
GPY10_RS18445	COG3781	membrane
GPY10_RS18450	COG0583	DNA-binding transcription factor activity
GPY10_RS18455	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPY10_RS18470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPY10_RS18480	COG0330	HflC and HflK could
GPY10_RS18505	COG1917	Cupin 2, conserved barrel domain protein
GPY10_RS18505	COG2207	Transcriptional regulator
GPY10_RS18510	COG0697	spore germination
GPY10_RS18515	COG0583	DNA-binding transcription factor activity
GPY10_RS18525	COG0463	Glycosyl transferase, family 2
GPY10_RS18590	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GPY10_RS18600	COG1309	transcriptional regulator
GPY10_RS18605	COG0513	Belongs to the DEAD box helicase family
GPY10_RS18615	COG0814	amino acid
GPY10_RS18620	COG0840	transmembrane signaling receptor activity
GPY10_RS18625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPY10_RS18630	COG5001	Diguanylate cyclase
GPY10_RS18630	COG3447	MASE1 domain protein
GPY10_RS18630	COG5002	protein histidine kinase activity
GPY10_RS18635	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GPY10_RS18645	COG1984	allophanate hydrolase subunit 2
GPY10_RS18655	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GPY10_RS18660	COG4181	ATPase activity
GPY10_RS18670	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPY10_RS18675	COG1716	ATPase activity
GPY10_RS18675	COG5001	Diguanylate cyclase
GPY10_RS18705	COG0546	phosphoglycolate phosphatase activity
GPY10_RS18720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY10_RS18725	COG5001	Diguanylate cyclase
GPY10_RS18730	COG3706	GGDEF domain
GPY10_RS18740	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GPY10_RS18750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPY10_RS18755	COG0509	glycine decarboxylation via glycine cleavage system
GPY10_RS18760	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPY10_RS18760	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPY10_RS18780	COG3122	Protein conserved in bacteria
GPY10_RS18825	COG1280	lysine exporter protein (LysE YggA)
GPY10_RS18845	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPY10_RS18855	COG2985	domain, Protein
GPY10_RS18870	COG0840	transmembrane signaling receptor activity
GPY10_RS18885	COG0513	Belongs to the DEAD box helicase family
GPY10_RS18890	COG1280	lysine exporter protein (LysE YggA)
GPY10_RS18900	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GPY10_RS18910	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPY10_RS18945	COG3338	carbonate dehydratase activity
GPY10_RS18955	COG1566	PFAM secretion protein HlyD family protein
GPY10_RS18970	COG1686	Belongs to the peptidase S11 family
GPY10_RS18980	COG0765	amino acid transport
GPY10_RS18995	COG1522	sequence-specific DNA binding
GPY10_RS19005	COG1166	arginine decarboxylase activity
GPY10_RS19020	COG4176	ABC-type proline glycine betaine transport system permease component
GPY10_RS19045	COG2239	Acts as a magnesium transporter
GPY10_RS19050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPY10_RS19055	COG0459	protein refolding
GPY10_RS19060	COG0113	porphobilinogen synthase activity
GPY10_RS19070	COG3437	response regulator, receiver
GPY10_RS19070	COG0784	Response regulator, receiver
GPY10_RS19080	COG0583	DNA-binding transcription factor activity
GPY10_RS19090	COG0561	phosphatase activity
GPY10_RS19095	COG0527	aspartate kinase activity
GPY10_RS19100	COG0662	Cupin 2, conserved barrel domain protein
GPY10_RS19105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPY10_RS19110	COG0456	acetyltransferase
GPY10_RS19120	COG0861	Integral membrane protein TerC family
GPY10_RS19130	COG0534	Mate efflux family protein
GPY10_RS19135	COG2154	pterin-4-alpha-carbinolamine dehydratase
GPY10_RS19145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY10_RS19155	COG0642	Histidine kinase
GPY10_RS19160	COG0745	RESPONSE REGULATOR receiver
GPY10_RS19180	COG1022	Amp-dependent synthetase and ligase
GPY10_RS19190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY10_RS19250	COG3700	Belongs to the class B bacterial acid phosphatase family
GPY10_RS19270	COG2171	N-acyltransferase activity
GPY10_RS19280	COG1765	OsmC-like protein
GPY10_RS19295	COG5001	Diguanylate cyclase
GPY10_RS19295	COG3300	MHYT domain
GPY10_RS19300	COG5002	protein histidine kinase activity
GPY10_RS19300	COG0784	Response regulator, receiver
GPY10_RS19300	COG2205	protein histidine kinase activity
GPY10_RS19325	COG2200	EAL domain
GPY10_RS19330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY10_RS19360	COG1522	sequence-specific DNA binding
GPY10_RS19375	COG0748	coenzyme F420 binding
GPY10_RS19380	COG3721	Heme iron utilization protein
GPY10_RS19385	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GPY10_RS19390	COG0811	peptide transport
GPY10_RS19395	COG0848	biopolymer transport protein
GPY10_RS19405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY10_RS19410	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GPY10_RS19440	COG3217	Mosc domain protein beta barrel domain protein
GPY10_RS19440	COG0633	Ferredoxin
GPY10_RS19445	COG0418	dihydroorotase activity
GPY10_RS19450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY10_RS19455	COG2354	Protein conserved in bacteria
GPY10_RS19475	COG1349	DNA-binding transcription factor activity
GPY10_RS19515	COG3842	ATPase activity
GPY10_RS19555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY10_RS19565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY10_RS19585	COG0517	IMP dehydrogenase activity
GPY10_RS19590	COG1414	Transcriptional regulator
GPY10_RS19605	COG1917	Cupin 2, conserved barrel domain protein
GPY10_RS19620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY10_RS19625	COG0800	Aldolase
GPY10_RS19645	COG1175	transmembrane transport
GPY10_RS19650	COG0395	ABC-type sugar transport system, permease component
GPY10_RS19655	COG3842	ATPase activity
GPY10_RS19660	COG1653	transport
GPY10_RS19670	COG0534	Mate efflux family protein
GPY10_RS19675	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY10_RS19680	COG0823	Involved in the tonB-independent uptake of proteins
GPY10_RS19685	COG0393	Putative heavy-metal-binding
GPY10_RS19695	COG1522	sequence-specific DNA binding
GPY10_RS19715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPY10_RS19750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY10_RS19755	COG0784	Response regulator, receiver
GPY10_RS19755	COG0835	chemotaxis
GPY10_RS19760	COG2315	Protein conserved in bacteria
GPY10_RS19765	COG1846	Transcriptional regulator
GPY10_RS19775	COG3706	GGDEF domain
GPY10_RS19795	COG3706	GGDEF domain
GPY10_RS19820	COG5001	Diguanylate cyclase
GPY10_RS19830	COG1741	Belongs to the pirin family
GPY10_RS19835	COG0745	RESPONSE REGULATOR receiver
GPY10_RS19840	COG2205	protein histidine kinase activity
GPY10_RS19940	COG3501	Rhs element vgr protein
GPY10_RS19950	COG2814	Major facilitator Superfamily
GPY10_RS19960	COG3123	guanosine phosphorylase activity
GPY10_RS19970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY10_RS19975	COG0569	domain protein
GPY10_RS19985	COG2211	Major facilitator Superfamily
GPY10_RS19990	COG0840	transmembrane signaling receptor activity
GPY10_RS19995	COG1067	ATP-dependent peptidase activity
GPY10_RS20010	COG0583	DNA-binding transcription factor activity
GPY10_RS20015	COG1620	l-lactate permease
GPY10_RS20020	COG1304	FMN binding
GPY10_RS20045	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPY10_RS20055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY10_RS20065	COG3152	Membrane
GPY10_RS20085	COG0583	DNA-binding transcription factor activity
GPY10_RS20100	COG1942	4-Oxalocrotonate Tautomerase
GPY10_RS20110	COG0625	glutathione transferase activity
GPY10_RS20120	COG0477	Major facilitator Superfamily
GPY10_RS20125	COG0697	spore germination
GPY10_RS20130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY10_RS20150	COG2169	Transcriptional regulator
GPY10_RS20170	COG5001	Diguanylate cyclase
GPY10_RS20170	COG3447	MASE1 domain protein
GPY10_RS20170	COG5002	protein histidine kinase activity
GPY10_RS20180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY10_RS20195	COG0109	protoheme IX farnesyltransferase activity
GPY10_RS20200	COG1612	heme a metabolic process
GPY10_RS20230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPY10_RS20240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY10_RS20245	COG1902	pentaerythritol trinitrate reductase activity
GPY10_RS20255	COG1280	lysine exporter protein (LysE YggA)
GPY10_RS20275	COG0179	Fumarylacetoacetate (FAA) hydrolase
GPY10_RS20280	COG1846	Transcriptional regulator
GPY10_RS20285	COG1764	response to oxidative stress
GPY10_RS20335	COG1301	dicarboxylic acid transport
GPY10_RS20340	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GPY10_RS20350	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPY10_RS20355	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GPY10_RS20360	COG2259	Doxx family
GPY10_RS20365	COG0402	S-adenosylhomocysteine deaminase activity
GPY10_RS20390	COG0363	glucosamine-6-phosphate deaminase activity
GPY10_RS20405	COG0739	heme binding
GPY10_RS20410	COG2213	PTS system mannitol-specific
GPY10_RS20410	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY10_RS20420	COG3722	fumarate hydratase activity
GPY10_RS20435	COG1473	amidohydrolase
GPY10_RS20440	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY10_RS20455	COG0095	Lipoate-protein ligase
GPY10_RS20460	COG0443	Heat shock 70 kDa protein
GPY10_RS20480	COG2176	DNA-directed DNA polymerase activity
GPY10_RS20530	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPY10_RS20540	COG1403	HNH endonuclease
GPY10_RS20565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY10_RS20575	COG3304	Inner membrane component domain
GPY10_RS20580	COG2329	Antibiotic biosynthesis monooxygenase
GPY10_RS20595	COG1609	Transcriptional regulator
GPY10_RS20595	COG2207	Transcriptional regulator
GPY10_RS20600	COG1335	isochorismatase
GPY10_RS20615	COG2910	NAD(P)H-binding
GPY10_RS20620	COG0583	DNA-binding transcription factor activity
GPY10_RS20635	COG1349	DNA-binding transcription factor activity
GPY10_RS20640	COG2084	Dehydrogenase
GPY10_RS20645	COG3395	kinase activity
GPY10_RS20650	COG0235	Class ii aldolase
GPY10_RS20655	COG3622	Belongs to the hyi family
GPY10_RS20660	COG2610	gluconate transmembrane transporter activity
GPY10_RS20665	COG1522	sequence-specific DNA binding
GPY10_RS20670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPY10_RS20675	COG0724	RNA recognition motif
GPY10_RS20690	COG2226	methyltransferase
GPY10_RS20695	COG0583	DNA-binding transcription factor activity
GPY10_RS20705	COG0513	Belongs to the DEAD box helicase family
GPY10_RS20710	COG0859	PFAM glycosyl transferase family 9
GPY10_RS20715	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY10_RS20730	COG0840	transmembrane signaling receptor activity
GPY10_RS20770	COG0259	pyridoxamine-phosphate oxidase activity
GPY10_RS20815	COG2201	protein-glutamate methylesterase activity
GPY10_RS20825	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPY10_RS20830	COG0840	transmembrane signaling receptor activity
GPY10_RS20835	COG0835	chemotaxis
GPY10_RS20840	COG0835	chemotaxis
GPY10_RS20845	COG2198	Histidine kinase
GPY10_RS20845	COG0643	Histidine kinase
GPY10_RS20850	COG0745	RESPONSE REGULATOR receiver
GPY10_RS20860	COG1444	tRNA N-acetyltransferase activity
GPY10_RS20865	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY10_RS20900	COG0217	transcriptional regulatory protein
GPY10_RS20915	COG2084	Dehydrogenase
GPY10_RS20930	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GPY10_RS20935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPY10_RS20940	COG1845	cytochrome c oxidase, subunit III
GPY10_RS20945	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GPY10_RS20960	COG2909	trisaccharide binding
GPY10_RS20965	COG0058	SHG alpha-glucan phosphorylase activity
GPY10_RS20970	COG1640	4-alpha-glucanotransferase
GPY10_RS20975	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GPY10_RS20985	COG3501	Rhs element vgr protein
GPY10_RS21030	COG0471	metal ion transport
GPY10_RS21040	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPY10_RS21045	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPY10_RS21050	COG3033	Beta-eliminating lyase
GPY10_RS21060	COG2188	Transcriptional regulator
GPY10_RS21065	COG1131	(ABC) transporter
GPY10_RS21090	COG3383	formate dehydrogenase (NAD+) activity
GPY10_RS21100	COG0671	phosphoesterase, PA-phosphatase related
GPY10_RS21110	COG1132	(ABC) transporter
GPY10_RS21130	COG4580	involved in the transport of maltose and maltodextrins
GPY10_RS21145	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GPY10_RS21150	COG1162	GTPase activity
GPY10_RS21160	COG1999	signal sequence binding
GPY10_RS21175	COG0786	glutamate:sodium symporter activity
GPY10_RS21210	COG1566	PFAM secretion protein HlyD family protein
GPY10_RS21220	COG3706	GGDEF domain
GPY10_RS21235	COG0813	purine-nucleoside phosphorylase activity
GPY10_RS21240	COG3272	Protein of unknown function (DUF1722)
GPY10_RS21250	COG0415	Belongs to the DNA photolyase family
GPY10_RS21255	COG1388	LysM domain
GPY10_RS21255	COG1376	ErfK ybiS ycfS ynhG family protein
GPY10_RS21265	COG0513	Belongs to the DEAD box helicase family
GPY10_RS21270	COG0840	transmembrane signaling receptor activity
GPY10_RS21275	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY10_RS21280	COG0573	inorganic phosphate transmembrane transporter activity
GPY10_RS21285	COG0581	inorganic phosphate transmembrane transporter activity
GPY10_RS21295	COG2199	diguanylate cyclase activity
GPY10_RS21310	COG0659	secondary active sulfate transmembrane transporter activity
GPY10_RS21325	COG0739	heme binding
GPY10_RS21330	COG3300	MHYT domain
GPY10_RS21330	COG5001	Diguanylate cyclase
GPY10_RS21335	COG0583	DNA-binding transcription factor activity
GPY10_RS21340	COG2814	Major facilitator Superfamily
GPY10_RS21355	COG0697	spore germination
GPY10_RS21360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY10_RS21370	COG0583	DNA-binding transcription factor activity
GPY10_RS21375	COG0778	Nitroreductase
GPY10_RS21380	COG1342	Belongs to the UPF0251 family
GPY10_RS21390	COG0583	DNA-binding transcription factor activity
GPY10_RS21395	COG3384	dioxygenase
GPY10_RS21400	COG0840	transmembrane signaling receptor activity
GPY10_RS21425	COG4774	siderophore transport
GPY10_RS21430	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GPY10_RS21435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY10_RS21440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY10_RS21445	COG1120	ATPase activity
GPY10_RS21455	COG0583	DNA-binding transcription factor activity
GPY10_RS21460	COG1028	Short-chain dehydrogenase reductase Sdr
GPY10_RS21465	COG3240	lipase activity
GPY10_RS21485	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPY10_RS21490	COG1349	DNA-binding transcription factor activity
GPY10_RS21495	COG0673	inositol 2-dehydrogenase activity
GPY10_RS21500	COG4702	Belongs to the UPF0303 family
GPY10_RS21510	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPY10_RS21525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY10_RS21545	COG2814	Major facilitator Superfamily
GPY10_RS21550	COG0583	DNA-binding transcription factor activity
GPY10_RS21555	COG1902	pentaerythritol trinitrate reductase activity
GPY10_RS21560	COG0656	L-ascorbic acid biosynthetic process
GPY10_RS21565	COG2200	EAL domain
GPY10_RS21575	COG3842	ATPase activity
GPY10_RS21605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY10_RS21620	COG2130	NADP-dependent
GPY10_RS21625	COG1309	transcriptional regulator
GPY10_RS21630	COG0564	pseudouridine synthase activity
GPY10_RS21640	COG1230	cation diffusion facilitator family transporter
GPY10_RS21645	COG1846	Transcriptional regulator
GPY10_RS21650	COG1280	lysine exporter protein (LysE YggA)
GPY10_RS21745	COG3501	Rhs element vgr protein
GPY10_RS21760	COG1869	D-ribose catabolic process
GPY10_RS21765	COG1129	ABC transporter
GPY10_RS21770	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPY10_RS21775	COG1879	ABC-type sugar transport system periplasmic component
GPY10_RS21780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY10_RS21790	COG0583	DNA-binding transcription factor activity
GPY10_RS21795	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GPY10_RS21800	COG0584	glycerophosphoryl diester phosphodiesterase
GPY10_RS21805	COG2271	Major facilitator Superfamily
GPY10_RS21810	COG3300	MHYT domain
GPY10_RS21810	COG5001	Diguanylate cyclase
GPY10_RS21835	COG2188	Transcriptional regulator
GPY10_RS21840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY10_RS21840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY10_RS21840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY10_RS21845	COG0383	alpha-mannosidase activity
GPY10_RS21860	COG2204	response regulator
GPY10_RS21875	COG0579	oxidoreductase
GPY10_RS21885	COG3530	Putative quorum-sensing-regulated virulence factor
GPY10_RS21895	COG0589	response to stress
GPY10_RS21900	COG3171	Protein conserved in bacteria
GPY10_RS21930	COG0583	DNA-binding transcription factor activity
GPY10_RS21955	COG4948	Mandelate Racemase Muconate Lactonizing
GPY10_RS21980	COG1012	belongs to the aldehyde dehydrogenase family
GPY10_RS21985	COG3724	N-succinylarginine dihydrolase activity
GPY10_RS21995	COG3706	GGDEF domain
GPY10_RS21995	COG0745	RESPONSE REGULATOR receiver
GPY10_RS22000	COG5002	protein histidine kinase activity
GPY10_RS22000	COG2205	protein histidine kinase activity
GPY10_RS22000	COG0784	Response regulator, receiver
GPY10_RS22010	COG3706	GGDEF domain
GPY10_RS22025	COG2304	oxidoreductase activity
GPY10_RS22045	COG0714	Associated with various cellular activities
GPY10_RS22065	COG0366	Alpha amylase catalytic
GPY10_RS22075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY10_RS22080	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY10_RS22090	COG3604	Transcriptional regulator