locus-tag	class	description
AL536_RS00020	COG0840	transmembrane signaling receptor activity
AL536_RS00040	COG0513	Belongs to the DEAD box helicase family
AL536_RS00050	COG0583	DNA-binding transcription factor activity
AL536_RS00055	COG2226	methyltransferase
AL536_RS00070	COG0724	RNA recognition motif
AL536_RS00075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL536_RS00080	COG1522	sequence-specific DNA binding
AL536_RS00085	COG2610	gluconate transmembrane transporter activity
AL536_RS00090	COG3622	Belongs to the hyi family
AL536_RS00095	COG0235	Class ii aldolase
AL536_RS00100	COG3395	kinase activity
AL536_RS00105	COG2084	Dehydrogenase
AL536_RS00110	COG1349	DNA-binding transcription factor activity
AL536_RS00125	COG0583	DNA-binding transcription factor activity
AL536_RS00130	COG2910	NAD(P)H-binding
AL536_RS00145	COG1335	isochorismatase
AL536_RS00165	COG2329	Antibiotic biosynthesis monooxygenase
AL536_RS00170	COG3304	Inner membrane component domain
AL536_RS00180	COG2801	Transposase and inactivated derivatives
AL536_RS00185	COG2963	transposase activity
AL536_RS00190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_RS00225	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL536_RS00235	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL536_RS00250	COG0367	asparagine synthase
AL536_RS00290	COG2176	DNA-directed DNA polymerase activity
AL536_RS00310	COG0443	Heat shock 70 kDa protein
AL536_RS00315	COG0095	Lipoate-protein ligase
AL536_RS00330	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL536_RS00335	COG1473	amidohydrolase
AL536_RS00350	COG3722	fumarate hydratase activity
AL536_RS00360	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL536_RS00360	COG2213	PTS system mannitol-specific
AL536_RS00365	COG0739	heme binding
AL536_RS00380	COG0363	glucosamine-6-phosphate deaminase activity
AL536_RS00405	COG0402	S-adenosylhomocysteine deaminase activity
AL536_RS00410	COG2259	Doxx family
AL536_RS00415	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL536_RS00420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL536_RS00430	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AL536_RS00435	COG1301	dicarboxylic acid transport
AL536_RS00455	COG2169	Transcriptional regulator
AL536_RS00455	COG1917	Cupin 2, conserved barrel domain protein
AL536_RS00490	COG1764	response to oxidative stress
AL536_RS00495	COG1846	Transcriptional regulator
AL536_RS00500	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL536_RS00520	COG1280	lysine exporter protein (LysE YggA)
AL536_RS00530	COG1902	pentaerythritol trinitrate reductase activity
AL536_RS00535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL536_RS00545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL536_RS00580	COG0109	protoheme IX farnesyltransferase activity
AL536_RS00595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL536_RS00605	COG5002	protein histidine kinase activity
AL536_RS00605	COG5001	Diguanylate cyclase
AL536_RS00605	COG3447	MASE1 domain protein
AL536_RS00625	COG2169	Transcriptional regulator
AL536_RS00645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_RS00650	COG0697	spore germination
AL536_RS00655	COG3477	response to acidic pH
AL536_RS00660	COG0477	Major facilitator Superfamily
AL536_RS00665	COG0625	glutathione transferase activity
AL536_RS00675	COG1942	4-Oxalocrotonate Tautomerase
AL536_RS00690	COG0583	DNA-binding transcription factor activity
AL536_RS00710	COG3152	Membrane
AL536_RS00720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL536_RS00730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL536_RS00745	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL536_RS00760	COG1620	l-lactate permease
AL536_RS00765	COG0583	DNA-binding transcription factor activity
AL536_RS00770	COG4172	Belongs to the ABC transporter superfamily
AL536_RS00780	COG1067	ATP-dependent peptidase activity
AL536_RS00790	COG2211	Major facilitator Superfamily
AL536_RS00795	COG0668	transmembrane transport
AL536_RS00800	COG0569	domain protein
AL536_RS00805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL536_RS00815	COG3123	guanosine phosphorylase activity
AL536_RS00820	COG1741	Belongs to the pirin family
AL536_RS00830	COG5001	Diguanylate cyclase
AL536_RS00855	COG3706	GGDEF domain
AL536_RS00875	COG3706	GGDEF domain
AL536_RS00885	COG1846	Transcriptional regulator
AL536_RS00890	COG2315	Protein conserved in bacteria
AL536_RS00895	COG0784	Response regulator, receiver
AL536_RS00895	COG0835	chemotaxis
AL536_RS00900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL536_RS00915	COG1942	4-Oxalocrotonate Tautomerase
AL536_RS00935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL536_RS00955	COG1522	sequence-specific DNA binding
AL536_RS00965	COG0393	Putative heavy-metal-binding
AL536_RS00970	COG0823	Involved in the tonB-independent uptake of proteins
AL536_RS00975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL536_RS00980	COG0534	Mate efflux family protein
AL536_RS00990	COG1653	transport
AL536_RS00995	COG3842	ATPase activity
AL536_RS01000	COG0395	ABC-type sugar transport system, permease component
AL536_RS01005	COG1175	transmembrane transport
AL536_RS01025	COG0800	Aldolase
AL536_RS01030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL536_RS01045	COG1917	Cupin 2, conserved barrel domain protein
AL536_RS01055	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_RS01060	COG1414	Transcriptional regulator
AL536_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL536_RS01095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_RS01135	COG3842	ATPase activity
AL536_RS01145	COG1175	transmembrane transport
AL536_RS01150	COG3833	ABC-type maltose transport systems, permease component
AL536_RS01175	COG1349	DNA-binding transcription factor activity
AL536_RS01195	COG2354	Protein conserved in bacteria
AL536_RS01200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL536_RS01205	COG0418	dihydroorotase activity
AL536_RS01215	COG3217	Mosc domain protein beta barrel domain protein
AL536_RS01215	COG0633	Ferredoxin
AL536_RS01245	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL536_RS01250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL536_RS01260	COG0848	biopolymer transport protein
AL536_RS01265	COG0811	peptide transport
AL536_RS01270	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL536_RS01275	COG3721	Heme iron utilization protein
AL536_RS01280	COG0748	coenzyme F420 binding
AL536_RS01290	COG0531	amino acid
AL536_RS01295	COG1522	sequence-specific DNA binding
AL536_RS01320	COG1151	hydroxylamine reductase activity
AL536_RS01325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL536_RS01330	COG2200	EAL domain
AL536_RS01355	COG2205	protein histidine kinase activity
AL536_RS01355	COG0784	Response regulator, receiver
AL536_RS01355	COG5002	protein histidine kinase activity
AL536_RS01360	COG3300	MHYT domain
AL536_RS01360	COG5001	Diguanylate cyclase
AL536_RS01375	COG1765	OsmC-like protein
AL536_RS01410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL536_RS01420	COG1022	Amp-dependent synthetase and ligase
AL536_RS01445	COG0642	Histidine kinase
AL536_RS01455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL536_RS01460	COG3186	Phenylalanine-4-hydroxylase
AL536_RS01465	COG2154	pterin-4-alpha-carbinolamine dehydratase
AL536_RS01470	COG0534	Mate efflux family protein
AL536_RS01480	COG0861	Integral membrane protein TerC family
AL536_RS01490	COG0456	acetyltransferase
AL536_RS01495	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL536_RS01500	COG0662	Cupin 2, conserved barrel domain protein
AL536_RS01505	COG0527	aspartate kinase activity
AL536_RS01510	COG0561	phosphatase activity
AL536_RS01520	COG0583	DNA-binding transcription factor activity
AL536_RS01530	COG0784	Response regulator, receiver
AL536_RS01530	COG3437	response regulator, receiver
AL536_RS01540	COG0113	porphobilinogen synthase activity
AL536_RS01545	COG0459	protein refolding
AL536_RS01550	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL536_RS01555	COG2239	Acts as a magnesium transporter
AL536_RS01575	COG2113	Glycine betaine
AL536_RS01580	COG4176	ABC-type proline glycine betaine transport system permease component
AL536_RS01585	COG4175	Glycine betaine
AL536_RS01595	COG1166	arginine decarboxylase activity
AL536_RS01605	COG1522	sequence-specific DNA binding
AL536_RS01620	COG0765	amino acid transport
AL536_RS01630	COG1686	Belongs to the peptidase S11 family
AL536_RS01645	COG1566	PFAM secretion protein HlyD family protein
AL536_RS01655	COG3338	carbonate dehydratase activity
AL536_RS01690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL536_RS01700	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL536_RS01710	COG1280	lysine exporter protein (LysE YggA)
AL536_RS01715	COG0513	Belongs to the DEAD box helicase family
AL536_RS01730	COG0840	transmembrane signaling receptor activity
AL536_RS01745	COG2985	domain, Protein
AL536_RS01755	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL536_RS01775	COG1280	lysine exporter protein (LysE YggA)
AL536_RS01820	COG3122	Protein conserved in bacteria
AL536_RS01840	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL536_RS01840	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL536_RS01845	COG0509	glycine decarboxylation via glycine cleavage system
AL536_RS01860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL536_RS01870	COG3706	GGDEF domain
AL536_RS01875	COG5001	Diguanylate cyclase
AL536_RS01880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL536_RS01895	COG0546	phosphoglycolate phosphatase activity
AL536_RS01915	COG0484	heat shock protein binding
AL536_RS01925	COG5001	Diguanylate cyclase
AL536_RS01925	COG1716	ATPase activity
AL536_RS01930	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL536_RS01940	COG4181	ATPase activity
AL536_RS01945	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL536_RS01955	COG1984	allophanate hydrolase subunit 2
AL536_RS01965	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL536_RS01970	COG5002	protein histidine kinase activity
AL536_RS01970	COG5001	Diguanylate cyclase
AL536_RS01970	COG3447	MASE1 domain protein
AL536_RS01975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL536_RS01980	COG0840	transmembrane signaling receptor activity
AL536_RS01985	COG0814	amino acid
AL536_RS01990	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AL536_RS01995	COG0513	Belongs to the DEAD box helicase family
AL536_RS02000	COG1309	transcriptional regulator
AL536_RS02010	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL536_RS02030	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AL536_RS02060	COG0840	transmembrane signaling receptor activity
AL536_RS02070	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL536_RS02080	COG0463	Glycosyl transferase, family 2
AL536_RS02090	COG0583	DNA-binding transcription factor activity
AL536_RS02095	COG0697	spore germination
AL536_RS02100	COG1917	Cupin 2, conserved barrel domain protein
AL536_RS02100	COG2207	Transcriptional regulator
AL536_RS02125	COG0330	HflC and HflK could
AL536_RS02135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL536_RS02145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL536_RS02150	COG0583	DNA-binding transcription factor activity
AL536_RS02155	COG3781	membrane
AL536_RS02165	COG1271	oxidase subunit
AL536_RS02170	COG1294	oxidase, subunit
AL536_RS02175	COG0800	Aldolase
AL536_RS02180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL536_RS02185	COG1904	glucuronate isomerase
AL536_RS02190	COG0246	Mannitol dehydrogenase
AL536_RS02205	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL536_RS02215	COG2186	Transcriptional regulator
AL536_RS02225	COG2390	Transcriptional regulator
AL536_RS02235	COG1070	Carbohydrate kinase
AL536_RS02245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL536_RS02260	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL536_RS02290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL536_RS02335	COG2116	formate transmembrane transporter activity
AL536_RS02340	COG1648	precorrin-2 dehydrogenase activity
AL536_RS02340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL536_RS02370	COG3118	belongs to the thioredoxin family
AL536_RS02375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL536_RS02390	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL536_RS02400	COG1596	polysaccharide export
AL536_RS02425	COG0438	transferase activity, transferring glycosyl groups
AL536_RS02430	COG0297	glycogen (starch) synthase activity
AL536_RS02430	COG0438	transferase activity, transferring glycosyl groups
AL536_RS02445	COG0247	lactate metabolic process
AL536_RS02450	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AL536_RS02455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL536_RS02460	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL536_RS02465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL536_RS02510	COG4386	tail sheath protein
AL536_RS02550	COG4695	Portal protein
AL536_RS02710	COG4974	Belongs to the 'phage' integrase family
AL536_RS02725	COG3132	Protein of unknown function, DUF480
AL536_RS02730	COG2827	Endonuclease containing a URI domain
AL536_RS02740	COG1879	ABC-type sugar transport system periplasmic component
AL536_RS02745	COG5002	protein histidine kinase activity
AL536_RS02745	COG0784	Response regulator, receiver
AL536_RS02765	COG1492	cobalamin metabolic process
AL536_RS02770	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL536_RS02775	COG4149	molybdate abc transporter
AL536_RS02780	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL536_RS02795	COG1289	transmembrane transporter activity
AL536_RS02835	COG0210	DNA helicase
AL536_RS02840	COG1335	isochorismatase
AL536_RS02845	COG1803	Methylglyoxal synthase
AL536_RS02850	COG1879	ABC-type sugar transport system periplasmic component
AL536_RS02855	COG0784	Response regulator, receiver
AL536_RS02855	COG2198	Histidine kinase
AL536_RS02855	COG2205	protein histidine kinase activity
AL536_RS02860	COG0469	pyruvate kinase activity
AL536_RS02865	COG2271	Major facilitator Superfamily
AL536_RS02890	COG1979	alcohol dehydrogenase
AL536_RS02895	COG2207	Transcriptional regulator
AL536_RS02910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL536_RS02935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL536_RS02940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL536_RS02950	COG0183	Belongs to the thiolase family
AL536_RS02985	COG0243	molybdopterin cofactor binding
AL536_RS03000	COG3850	Histidine kinase
AL536_RS03005	COG2197	response regulator
AL536_RS03010	COG3069	C4-dicarboxylate transmembrane transporter activity
AL536_RS03025	COG2814	Major facilitator Superfamily
AL536_RS03030	COG0840	transmembrane signaling receptor activity
AL536_RS03035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL536_RS03040	COG0545	Peptidyl-prolyl cis-trans isomerase
AL536_RS03055	COG0840	transmembrane signaling receptor activity
AL536_RS03060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL536_RS03075	COG2897	thiosulfate sulfurtransferase activity
AL536_RS03080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL536_RS03090	COG0302	gtp cyclohydrolase
AL536_RS03095	COG0531	amino acid
AL536_RS03105	COG4303	Ethanolamine ammonia lyase large subunit
AL536_RS03110	COG2207	Transcriptional regulator
AL536_RS03115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL536_RS03115	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL536_RS03120	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AL536_RS03125	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL536_RS03135	COG1011	Hydrolase
AL536_RS03140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL536_RS03150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL536_RS03155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL536_RS03160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL536_RS03170	COG3842	ATPase activity
AL536_RS03190	COG2866	Carboxypeptidase
AL536_RS03215	COG4166	transmembrane transport
AL536_RS03220	COG4174	ABC transporter (Permease)
AL536_RS03225	COG4239	(ABC) transporter, permease
AL536_RS03230	COG4172	Belongs to the ABC transporter superfamily
AL536_RS03235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL536_RS03265	COG3706	GGDEF domain
AL536_RS03280	COG2501	S4 domain
AL536_RS03320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL536_RS03345	COG1979	alcohol dehydrogenase
AL536_RS03350	COG2207	Transcriptional regulator
AL536_RS03370	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL536_RS03380	COG0488	(ABC) transporter
AL536_RS03390	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL536_RS03400	COG2814	Major facilitator Superfamily
AL536_RS03420	COG3710	Transcriptional regulator
AL536_RS03450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_RS03465	COG2233	PERMEase
AL536_RS03485	COG1953	Uracil, thiamine, allantoin
AL536_RS03495	COG0765	amino acid transport
AL536_RS03500	COG0765	amino acid transport
AL536_RS03530	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL536_RS03550	COG0402	S-adenosylhomocysteine deaminase activity
AL536_RS03555	COG2351	hydroxyisourate hydrolase activity
AL536_RS03585	COG1079	Belongs to the binding-protein-dependent transport system permease family
AL536_RS03590	COG4603	Belongs to the binding-protein-dependent transport system permease family
AL536_RS03595	COG3845	ABC transporter
AL536_RS03600	COG1309	transcriptional regulator
AL536_RS03635	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL536_RS03640	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL536_RS03650	COG0745	RESPONSE REGULATOR receiver
AL536_RS03665	COG0023	Translation Initiation Factor
AL536_RS03680	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL536_RS03690	COG0045	succinate-CoA ligase (ADP-forming) activity
AL536_RS03690	COG1042	CoA-binding domain protein
AL536_RS03690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL536_RS03695	COG0583	DNA-binding transcription factor activity
AL536_RS03700	COG1629	transport
AL536_RS03700	COG4771	TonB-dependent receptor
AL536_RS03720	COG2050	protein possibly involved in aromatic compounds catabolism
AL536_RS03725	COG0501	Belongs to the peptidase M48B family
AL536_RS03730	COG2824	Alkylphosphonate utilization operon protein PhnA
AL536_RS03740	COG0861	Integral membrane protein TerC family
AL536_RS03745	COG0737	Belongs to the 5'-nucleotidase family
AL536_RS03750	COG3593	DNA synthesis involved in DNA repair
AL536_RS03760	COG0583	DNA-binding transcription factor activity
AL536_RS03765	COG2116	formate transmembrane transporter activity
AL536_RS03770	COG2353	YceI-like domain
AL536_RS03775	COG3038	cytochrome b561
AL536_RS03800	COG5001	Diguanylate cyclase
AL536_RS03810	COG0243	molybdopterin cofactor binding
AL536_RS03815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL536_RS03820	COG0543	2 iron, 2 sulfur cluster binding
AL536_RS03820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL536_RS03825	COG2205	protein histidine kinase activity
AL536_RS03825	COG0784	Response regulator, receiver
AL536_RS03825	COG5002	protein histidine kinase activity
AL536_RS03830	COG3437	response regulator, receiver
AL536_RS03840	COG2207	Transcriptional regulator
AL536_RS03845	COG0582	viral genome integration into host DNA
AL536_RS03855	COG2916	Histone family protein nucleoid-structuring protein H-NS
AL536_RS03860	COG2200	EAL domain
AL536_RS03860	COG2202	Pas domain
AL536_RS03860	COG2199	diguanylate cyclase activity
AL536_RS03875	COG2200	EAL domain
AL536_RS03920	COG2181	nitrate reductase activity
AL536_RS03925	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL536_RS03930	COG1140	nitrate reductase beta subunit
AL536_RS03935	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL536_RS03940	COG2223	nitrite transmembrane transporter activity
AL536_RS03945	COG3850	Histidine kinase
AL536_RS03950	COG2197	response regulator
AL536_RS03955	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AL536_RS03965	COG0840	transmembrane signaling receptor activity
AL536_RS03965	COG3290	protein histidine kinase activity
AL536_RS04015	COG1518	maintenance of DNA repeat elements
AL536_RS04030	COG1609	Transcriptional regulator
AL536_RS04040	COG2017	converts alpha-aldose to the beta-anomer
AL536_RS04045	COG3459	Glycosyltransferase 36 associated
AL536_RS04055	COG2723	6-phospho-beta-galactosidase activity
AL536_RS04060	COG0395	ABC-type sugar transport system, permease component
AL536_RS04065	COG1175	transmembrane transport
AL536_RS04075	COG1609	Transcriptional regulator
AL536_RS04080	COG0840	transmembrane signaling receptor activity
AL536_RS04090	COG0534	Mate efflux family protein
AL536_RS04105	COG2003	Belongs to the UPF0758 family
AL536_RS04140	COG0328	RNA-DNA hybrid ribonuclease activity
AL536_RS04200	COG0523	cobalamin synthesis protein
AL536_RS04215	COG0156	8-amino-7-oxononanoate synthase activity
AL536_RS04220	COG0784	Response regulator, receiver
AL536_RS04220	COG2205	protein histidine kinase activity
AL536_RS04225	COG0419	ATPase involved in DNA repair
AL536_RS04235	COG1609	Transcriptional regulator
AL536_RS04240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL536_RS04240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL536_RS04245	COG1105	Belongs to the carbohydrate kinase PfkB family
AL536_RS04250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_RS04250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_RS04250	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL536_RS04255	COG4067	protein conserved in archaea
AL536_RS04255	COG0189	ligase activity
AL536_RS04265	COG0602	queuosine metabolic process
AL536_RS04270	COG1328	CTP reductase activity
AL536_RS04335	COG1280	lysine exporter protein (LysE YggA)
AL536_RS04340	COG0745	RESPONSE REGULATOR receiver
AL536_RS04350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL536_RS04360	COG0583	DNA-binding transcription factor activity
AL536_RS04375	COG1309	transcriptional regulator
AL536_RS04380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL536_RS04410	COG1335	isochorismatase
AL536_RS04415	COG4977	sequence-specific DNA binding
AL536_RS04420	COG0456	acetyltransferase
AL536_RS04430	COG1280	lysine exporter protein (LysE YggA)
AL536_RS04435	COG0494	nUDIX hydrolase
AL536_RS04445	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL536_RS04475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL536_RS04495	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_RS04505	COG0454	-acetyltransferase
AL536_RS04565	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL536_RS04570	COG0789	Transcriptional regulator
AL536_RS04620	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_RS04665	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL536_RS04670	COG0513	Belongs to the DEAD box helicase family
AL536_RS04685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL536_RS04695	COG0583	DNA-binding transcription factor activity
AL536_RS04700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL536_RS04710	COG3710	Transcriptional regulator
AL536_RS04715	COG4232	protein-disulfide reductase activity
AL536_RS04720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL536_RS04725	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL536_RS04735	COG1252	NADH dehydrogenase
AL536_RS04745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_RS04750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_RS04760	COG2207	Transcriptional regulator
AL536_RS04765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL536_RS04765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_RS04765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_RS04775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_RS04790	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AL536_RS04795	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AL536_RS04800	COG1349	DNA-binding transcription factor activity
AL536_RS04805	COG0110	maltose O-acetyltransferase activity
AL536_RS04810	COG3706	GGDEF domain
AL536_RS04820	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AL536_RS04830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL536_RS04840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL536_RS04850	COG0747	negative chemotaxis
AL536_RS04855	COG4172	Belongs to the ABC transporter superfamily
AL536_RS04865	COG3437	response regulator, receiver
AL536_RS04870	COG2205	protein histidine kinase activity
AL536_RS04870	COG2198	Histidine kinase
AL536_RS04870	COG0784	Response regulator, receiver
AL536_RS04880	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL536_RS04905	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL536_RS04920	COG2423	ornithine cyclodeaminase activity
AL536_RS04930	COG4145	pantothenate transmembrane transporter activity
AL536_RS04935	COG0583	DNA-binding transcription factor activity
AL536_RS04940	COG0435	Glutathione S-transferase
AL536_RS04945	COG0400	carboxylic ester hydrolase activity
AL536_RS04950	COG1280	lysine exporter protein (LysE YggA)
AL536_RS04965	COG1473	amidohydrolase
AL536_RS04985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL536_RS04990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL536_RS04995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL536_RS05005	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL536_RS05020	COG2721	sulfolactate sulfo-lyase activity
AL536_RS05075	COG0625	glutathione transferase activity
AL536_RS05080	COG1472	Belongs to the glycosyl hydrolase 3 family
AL536_RS05090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL536_RS05100	COG0573	inorganic phosphate transmembrane transporter activity
AL536_RS05105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL536_RS05125	COG1464	Belongs to the NlpA lipoprotein family
AL536_RS05130	COG0512	Glutamine amidotransferase of anthranilate synthase
AL536_RS05130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL536_RS05150	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL536_RS05165	COG0653	protein targeting
AL536_RS05170	COG2814	Major facilitator Superfamily
AL536_RS05180	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_RS05190	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_RS05200	COG1024	Enoyl-CoA hydratase
AL536_RS05205	COG1024	Enoyl-CoA hydratase
AL536_RS05210	COG1960	acyl-CoA dehydrogenase activity
AL536_RS05220	COG0183	Belongs to the thiolase family
AL536_RS05230	COG1960	acyl-CoA dehydrogenase activity
AL536_RS05235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL536_RS05240	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL536_RS05255	COG0450	alkyl hydroperoxide reductase
AL536_RS05260	COG3634	alkyl hydroperoxide reductase activity
AL536_RS05290	COG1609	Transcriptional regulator
AL536_RS05290	COG2207	Transcriptional regulator
AL536_RS05295	COG1454	alcohol dehydrogenase
AL536_RS05300	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL536_RS05340	COG1051	belongs to the nudix hydrolase family
AL536_RS05345	COG0784	Response regulator, receiver
AL536_RS05345	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL536_RS05370	COG2963	transposase activity
AL536_RS05375	COG2801	Transposase and inactivated derivatives
AL536_RS05385	COG0582	viral genome integration into host DNA
AL536_RS05400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL536_RS05415	COG1609	Transcriptional regulator
AL536_RS05415	COG2207	Transcriptional regulator
AL536_RS05420	COG4604	ABC transporter, ATP-binding protein
AL536_RS05425	COG4605	iron ion homeostasis
AL536_RS05430	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL536_RS05455	COG5380	lipid catabolic process
AL536_RS05460	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AL536_RS05470	COG1522	sequence-specific DNA binding
AL536_RS05490	COG2814	Major facilitator Superfamily
AL536_RS05500	COG0840	transmembrane signaling receptor activity
AL536_RS05515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AL536_RS05520	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL536_RS05525	COG3279	Response regulator of the LytR AlgR family
AL536_RS05530	COG3275	phosphorelay sensor kinase activity
AL536_RS05535	COG4989	oxidoreductase activity
AL536_RS05550	COG0366	Alpha amylase catalytic
AL536_RS05555	COG3227	Zinc metalloprotease (Elastase)
AL536_RS05560	COG3047	cAMP biosynthetic process
AL536_RS05565	COG0071	Belongs to the small heat shock protein (HSP20) family
AL536_RS05580	COG0251	oxidation-reduction process
AL536_RS05605	COG4916	TIR domain
AL536_RS05625	COG1132	(ABC) transporter
AL536_RS05630	COG1132	(ABC) transporter
AL536_RS05640	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL536_RS05645	COG2246	polysaccharide biosynthetic process
AL536_RS05660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL536_RS05670	COG0242	peptide deformylase activity
AL536_RS05680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_RS05685	COG2084	Dehydrogenase
AL536_RS05695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL536_RS05700	COG0583	DNA-binding transcription factor activity
AL536_RS05750	COG1063	alcohol dehydrogenase
AL536_RS05755	COG0156	8-amino-7-oxononanoate synthase activity
AL536_RS05760	COG1012	belongs to the aldehyde dehydrogenase family
AL536_RS05765	COG3284	Transcriptional regulator
AL536_RS05775	COG0346	lactoylglutathione lyase activity
AL536_RS05795	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AL536_RS05805	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL536_RS05810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL536_RS05815	COG0363	glucosamine-6-phosphate deaminase activity
AL536_RS05820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL536_RS05835	COG0583	DNA-binding transcription factor activity
AL536_RS05850	COG0646	methionine synthase
AL536_RS05850	COG1410	methionine synthase
AL536_RS05855	COG0531	amino acid
AL536_RS05870	COG1473	amidohydrolase
AL536_RS05875	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL536_RS05880	COG1929	Belongs to the glycerate kinase type-1 family
AL536_RS05885	COG2610	gluconate transmembrane transporter activity
AL536_RS05890	COG3835	regulator
AL536_RS05895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL536_RS05900	COG4533	DNA binding
AL536_RS05915	COG0840	transmembrane signaling receptor activity
AL536_RS05970	COG4964	Belongs to the GSP D family
AL536_RS06010	COG0798	PFAM Bile acid sodium symporter
AL536_RS06035	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL536_RS06040	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL536_RS06045	COG1129	ABC transporter
AL536_RS06060	COG0604	alcohol dehydrogenase
AL536_RS06060	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_RS06060	COG3321	synthase
AL536_RS06070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_RS06075	COG4974	Belongs to the 'phage' integrase family
AL536_RS06080	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AL536_RS06095	COG1482	cell wall glycoprotein biosynthetic process
AL536_RS06100	COG0840	transmembrane signaling receptor activity
AL536_RS06105	COG4580	involved in the transport of maltose and maltodextrins
AL536_RS06110	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AL536_RS06115	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AL536_RS06125	COG1609	Transcriptional regulator
AL536_RS06135	COG2942	2-epimerase
AL536_RS06140	COG5578	integral membrane protein
AL536_RS06145	COG0395	ABC-type sugar transport system, permease component
AL536_RS06150	COG1175	transmembrane transport
AL536_RS06270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL536_RS06275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL536_RS06275	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL536_RS06285	COG0745	RESPONSE REGULATOR receiver
AL536_RS06305	COG3036	rescue of stalled ribosome
AL536_RS06310	COG1278	Cold shock
AL536_RS06315	COG4681	YaeQ
AL536_RS06325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL536_RS06325	COG1017	nitric oxide dioxygenase activity
AL536_RS06330	COG3604	Transcriptional regulator
AL536_RS06340	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL536_RS06345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL536_RS06355	COG0366	Alpha amylase catalytic
AL536_RS06375	COG0714	Associated with various cellular activities
AL536_RS06395	COG2304	oxidoreductase activity
AL536_RS06410	COG3706	GGDEF domain
AL536_RS06420	COG5002	protein histidine kinase activity
AL536_RS06420	COG0784	Response regulator, receiver
AL536_RS06420	COG2205	protein histidine kinase activity
AL536_RS06435	COG3724	N-succinylarginine dihydrolase activity
AL536_RS06440	COG1012	belongs to the aldehyde dehydrogenase family
AL536_RS06465	COG4948	Mandelate Racemase Muconate Lactonizing
AL536_RS06490	COG0583	DNA-binding transcription factor activity
AL536_RS06520	COG0589	response to stress
AL536_RS06530	COG3530	Putative quorum-sensing-regulated virulence factor
AL536_RS06540	COG0579	oxidoreductase
AL536_RS06555	COG2204	response regulator
AL536_RS06565	COG1929	Belongs to the glycerate kinase type-1 family
AL536_RS06570	COG0383	alpha-mannosidase activity
AL536_RS06575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_RS06575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_RS06575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL536_RS06580	COG2188	Transcriptional regulator
AL536_RS06605	COG3300	MHYT domain
AL536_RS06605	COG5001	Diguanylate cyclase
AL536_RS06610	COG2271	Major facilitator Superfamily
AL536_RS06615	COG0584	glycerophosphoryl diester phosphodiesterase
AL536_RS06620	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AL536_RS06625	COG0583	DNA-binding transcription factor activity
AL536_RS06635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL536_RS06640	COG1879	ABC-type sugar transport system periplasmic component
AL536_RS06645	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL536_RS06650	COG1129	ABC transporter
AL536_RS06655	COG1869	D-ribose catabolic process
AL536_RS06670	COG3501	Rhs element vgr protein
AL536_RS06670	COG3409	Peptidoglycan-binding domain 1 protein
AL536_RS06695	COG3829	transcription factor binding
AL536_RS06765	COG1280	lysine exporter protein (LysE YggA)
AL536_RS06770	COG1846	Transcriptional regulator
AL536_RS06785	COG0564	pseudouridine synthase activity
AL536_RS06790	COG1309	transcriptional regulator
AL536_RS06795	COG2130	NADP-dependent
AL536_RS06810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL536_RS06840	COG3842	ATPase activity
AL536_RS06850	COG2200	EAL domain
AL536_RS06855	COG0656	L-ascorbic acid biosynthetic process
AL536_RS06860	COG1902	pentaerythritol trinitrate reductase activity
AL536_RS06865	COG0583	DNA-binding transcription factor activity
AL536_RS06870	COG2814	Major facilitator Superfamily
AL536_RS06905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL536_RS06915	COG4702	Belongs to the UPF0303 family
AL536_RS06920	COG0673	inositol 2-dehydrogenase activity
AL536_RS06925	COG1349	DNA-binding transcription factor activity
AL536_RS06930	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL536_RS06950	COG3240	lipase activity
AL536_RS06955	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_RS06960	COG0583	DNA-binding transcription factor activity
AL536_RS06970	COG1120	ATPase activity
AL536_RS06975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL536_RS06980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL536_RS06985	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AL536_RS06990	COG4774	siderophore transport
AL536_RS07015	COG0840	transmembrane signaling receptor activity
AL536_RS07020	COG3384	dioxygenase
AL536_RS07025	COG0583	DNA-binding transcription factor activity
AL536_RS07035	COG1342	Belongs to the UPF0251 family
AL536_RS07040	COG0778	Nitroreductase
AL536_RS07045	COG0583	DNA-binding transcription factor activity
AL536_RS07055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL536_RS07060	COG0697	spore germination
AL536_RS07075	COG2814	Major facilitator Superfamily
AL536_RS07080	COG0583	DNA-binding transcription factor activity
AL536_RS07085	COG5001	Diguanylate cyclase
AL536_RS07085	COG3300	MHYT domain
AL536_RS07090	COG0739	heme binding
AL536_RS07105	COG0659	secondary active sulfate transmembrane transporter activity
AL536_RS07110	COG3314	Sporulation integral membrane protein YlbJ
AL536_RS07120	COG2199	diguanylate cyclase activity
AL536_RS07125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL536_RS07130	COG0581	inorganic phosphate transmembrane transporter activity
AL536_RS07135	COG0573	inorganic phosphate transmembrane transporter activity
AL536_RS07140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL536_RS07145	COG0840	transmembrane signaling receptor activity
AL536_RS07150	COG0513	Belongs to the DEAD box helicase family
AL536_RS07160	COG1376	ErfK ybiS ycfS ynhG family protein
AL536_RS07160	COG1388	LysM domain
AL536_RS07165	COG0415	Belongs to the DNA photolyase family
AL536_RS07175	COG3272	Protein of unknown function (DUF1722)
AL536_RS07180	COG0813	purine-nucleoside phosphorylase activity
AL536_RS07205	COG1566	PFAM secretion protein HlyD family protein
AL536_RS07240	COG0786	glutamate:sodium symporter activity
AL536_RS07255	COG1999	signal sequence binding
AL536_RS07265	COG1162	GTPase activity
AL536_RS07270	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AL536_RS07285	COG4580	involved in the transport of maltose and maltodextrins
AL536_RS07305	COG1132	(ABC) transporter
AL536_RS07315	COG0671	phosphoesterase, PA-phosphatase related
AL536_RS07325	COG3383	formate dehydrogenase (NAD+) activity
AL536_RS07330	COG0010	Belongs to the arginase family
AL536_RS07340	COG0840	transmembrane signaling receptor activity
AL536_RS07350	COG1131	(ABC) transporter
AL536_RS07355	COG2188	Transcriptional regulator
AL536_RS07365	COG3033	Beta-eliminating lyase
AL536_RS07370	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL536_RS07375	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL536_RS07385	COG0471	metal ion transport
AL536_RS07410	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AL536_RS07430	COG3501	Rhs element vgr protein
AL536_RS07440	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL536_RS07445	COG1640	4-alpha-glucanotransferase
AL536_RS07450	COG0058	SHG alpha-glucan phosphorylase activity
AL536_RS07455	COG2909	trisaccharide binding
AL536_RS07470	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL536_RS07475	COG1845	cytochrome c oxidase, subunit III
AL536_RS07480	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL536_RS07485	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL536_RS07500	COG2084	Dehydrogenase
AL536_RS07515	COG0217	transcriptional regulatory protein
AL536_RS07550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL536_RS07555	COG1444	tRNA N-acetyltransferase activity
AL536_RS07570	COG0643	Histidine kinase
AL536_RS07570	COG2198	Histidine kinase
AL536_RS07580	COG0835	chemotaxis
AL536_RS07585	COG0840	transmembrane signaling receptor activity
AL536_RS07590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL536_RS07600	COG2201	protein-glutamate methylesterase activity
AL536_RS07615	COG0745	RESPONSE REGULATOR receiver
AL536_RS07655	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL536_RS08060	COG0402	S-adenosylhomocysteine deaminase activity
AL536_RS08305	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL536_RS08760	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL536_RS08780	COG0531	amino acid
AL536_RS09140	COG1686	Belongs to the peptidase S11 family
AL536_RS09145	COG1686	Belongs to the peptidase S11 family
AL536_RS09475	COG3447	MASE1 domain protein
AL536_RS09475	COG5002	protein histidine kinase activity
AL536_RS09475	COG5001	Diguanylate cyclase
AL536_RS09540	COG0840	transmembrane signaling receptor activity
AL536_RS09770	COG0243	molybdopterin cofactor binding
AL536_RS10410	COG1289	transmembrane transporter activity
AL536_RS10595	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL536_RS10835	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL536_RS10835	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL536_RS10975	COG4239	(ABC) transporter, permease
AL536_RS11155	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL536_RS11360	COG3845	ABC transporter
AL536_RS11645	COG1140	nitrate reductase beta subunit
AL536_RS12055	COG1328	CTP reductase activity
AL536_RS12310	COG0513	Belongs to the DEAD box helicase family
AL536_RS12495	COG0601	transmembrane transport
AL536_RS12615	COG1473	amidohydrolase
AL536_RS12710	COG1472	Belongs to the glycosyl hydrolase 3 family
AL536_RS13210	COG1132	(ABC) transporter
AL536_RS13220	COG1132	(ABC) transporter
AL536_RS13490	COG3835	regulator
AL536_RS14235	COG5001	Diguanylate cyclase
AL536_RS14235	COG3300	MHYT domain
AL536_RS14295	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL536_RS14300	COG1129	ABC transporter
AL536_RS14950	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AL536_RS15015	COG3383	formate dehydrogenase (NAD+) activity
AL536_RS15080	COG0471	metal ion transport
AL536_RS15165	COG1640	4-alpha-glucanotransferase
AL536_RS15170	COG1640	4-alpha-glucanotransferase
AL536_RS15190	COG2909	trisaccharide binding
AL536_RS15470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL536_RS15750	COG0617	tRNA 3'-terminal CCA addition
AL536_RS15810	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL536_RS15810	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL536_RS15905	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL536_RS15965	COG0617	tRNA 3'-terminal CCA addition
AL536_RS15980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL536_RS16000	COG1643	Atp-dependent helicase
AL536_RS16190	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL536_RS16265	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL536_RS16360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL536_RS16455	COG0583	DNA-binding transcription factor activity
AL536_RS16530	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL536_RS17100	COG2608	mercury ion transmembrane transporter activity
AL536_RS17100	COG2217	Heavy metal translocating P-type atpase
AL536_RS17765	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL536_RS17770	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL536_RS18755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_RS18990	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL536_RS18995	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL536_RS19000	COG1169	isochorismate synthase
AL536_RS19285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL536_RS19345	COG2986	histidine ammonia-lyase
AL536_RS19420	COG0857	belongs to the CobB CobQ family
AL536_RS19420	COG0280	phosphate acetyltransferase
AL536_RS19450	COG3706	GGDEF domain
AL536_RS19520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL536_RS19550	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL536_RS19765	COG0297	glycogen (starch) synthase activity
AL536_RS19815	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AL536_RS19945	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL536_RS20135	COG1131	(ABC) transporter
AL536_RS20210	COG0714	Associated with various cellular activities
AL536_RS20310	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL536_RS20780	COG1129	ABC transporter
AL536_RS21060	COG0791	NLP P60 protein
AL536_RS21365	COG1067	ATP-dependent peptidase activity
AL536_RS21710	COG0243	molybdopterin cofactor binding
AL536_RS21720	COG0243	molybdopterin cofactor binding
AL536_RS21775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL536_RS22215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL536_RS22215	COG0072	phenylalanine-tRNA ligase activity
AL536_RS22220	COG0072	phenylalanine-tRNA ligase activity
AL536_RS22220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL536_RS22250	COG0322	excinuclease ABC activity
AL536_RS22260	COG0417	DNA replication proofreading
AL536_RS22265	COG0417	DNA replication proofreading