locus-tag	class	description
GO175_RS00150	COG2356	endonuclease I
GO175_RS00265	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GO175_RS00345	COG1475	DNA binding
GO175_RS00360	COG1475	DNA binding
GO175_RS00395	COG2003	Belongs to the UPF0758 family
GO175_RS00505	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GO175_RS00515	COG1677	Flagellar hook-basal body complex protein FliE
GO175_RS00520	COG2204	response regulator
GO175_RS00525	COG4191	Histidine kinase
GO175_RS00530	COG2204	response regulator
GO175_RS00535	COG1516	flagellar protein fliS
GO175_RS00545	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GO175_RS00550	COG1334	flagellar protein FlaG
GO175_RS00555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GO175_RS00560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GO175_RS00570	COG2837	iron assimilation
GO175_RS00590	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GO175_RS00600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GO175_RS00610	COG1393	Belongs to the ArsC family
GO175_RS00615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GO175_RS00620	COG1876	peptidase activity
GO175_RS00630	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GO175_RS00635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GO175_RS00640	COG2716	regulation of RNA biosynthetic process
GO175_RS00645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GO175_RS00665	COG4783	chaperone-mediated protein folding
GO175_RS00670	COG1393	Belongs to the ArsC family
GO175_RS00690	COG2233	PERMEase
GO175_RS00700	COG0737	Belongs to the 5'-nucleotidase family
GO175_RS00710	COG2912	Transglutaminase-like superfamily
GO175_RS00715	COG3094	Invasion gene expression up-regulator, SirB
GO175_RS00720	COG2890	protein-(glutamine-N5) methyltransferase activity
GO175_RS00725	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GO175_RS00730	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GO175_RS00735	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GO175_RS00745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GO175_RS00750	COG0193	aminoacyl-tRNA hydrolase activity
GO175_RS00850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GO175_RS00865	COG3951	Flagellar rod assembly protein muramidase FlgJ
GO175_RS00865	COG1705	Flagellar rod assembly protein muramidase FlgJ
GO175_RS00870	COG1706	bacterial-type flagellum-dependent cell motility
GO175_RS00875	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GO175_RS00880	COG4786	Flagellar basal body rod
GO175_RS00885	COG4787	bacterial-type flagellum-dependent cell motility
GO175_RS00890	COG1749	Flagellar hook protein flgE
GO175_RS00895	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GO175_RS00900	COG1558	bacterial-type flagellum-dependent cell motility
GO175_RS00905	COG1815	bacterial-type flagellum-dependent cell motility
GO175_RS00910	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GO175_RS00915	COG0835	chemotaxis
GO175_RS00915	COG0784	Response regulator, receiver
GO175_RS00925	COG2747	anti-sigma28 factor FlgM
GO175_RS00960	COG2194	sulfuric ester hydrolase activity
GO175_RS00965	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GO175_RS00985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GO175_RS00990	COG2608	mercury ion transmembrane transporter activity
GO175_RS00990	COG2217	Heavy metal translocating P-type atpase
GO175_RS01020	COG2840	Smr protein MutS2
GO175_RS01025	COG1187	pseudouridine synthase activity
GO175_RS01030	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GO175_RS01035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GO175_RS01040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GO175_RS01045	COG0121	glutamine amidotransferase
GO175_RS01050	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GO175_RS01055	COG1960	acyl-CoA dehydrogenase activity
GO175_RS01065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GO175_RS01070	COG0328	RNA-DNA hybrid ribonuclease activity
GO175_RS01075	COG2226	methyltransferase
GO175_RS01085	COG1388	LysM domain
GO175_RS01085	COG0741	lytic transglycosylase activity
GO175_RS01100	COG0347	Belongs to the P(II) protein family
GO175_RS01110	COG0037	tRNA processing
GO175_RS01115	COG0825	malonyl-CoA metabolic process
GO175_RS01120	COG0587	DNA-directed DNA polymerase activity
GO175_RS01140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO175_RS01145	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GO175_RS01150	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GO175_RS01160	COG0750	zinc metalloprotease
GO175_RS01165	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GO175_RS01170	COG0575	Belongs to the CDS family
GO175_RS01175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GO175_RS01200	COG0024	Methionine aminopeptidase
GO175_RS01205	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GO175_RS01215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GO175_RS01220	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GO175_RS01225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GO175_RS01245	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GO175_RS01245	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GO175_RS01250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GO175_RS01255	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GO175_RS01260	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GO175_RS01275	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GO175_RS01280	COG2252	PERMEase
GO175_RS01285	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GO175_RS01295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GO175_RS01305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GO175_RS01310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO175_RS01315	COG2195	Cleaves the N-terminal amino acid of tripeptides
GO175_RS01320	COG4067	protein conserved in archaea
GO175_RS01320	COG0189	ligase activity
GO175_RS01325	COG0189	ligase activity
GO175_RS01335	COG0733	neurotransmitter:sodium symporter activity
GO175_RS01340	COG2203	Gaf domain
GO175_RS01340	COG3706	GGDEF domain
GO175_RS01340	COG4251	negative regulation of phosphorylation
GO175_RS01340	COG5001	Diguanylate cyclase
GO175_RS01350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GO175_RS01365	COG1477	protein flavinylation
GO175_RS01370	COG2871	sodium ion transport
GO175_RS01375	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GO175_RS01380	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GO175_RS01390	COG1805	sodium ion transport
GO175_RS01395	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GO175_RS01400	COG0271	Belongs to the BolA IbaG family
GO175_RS01480	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GO175_RS01485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GO175_RS01490	COG0590	tRNA wobble adenosine to inosine editing
GO175_RS01500	COG0542	response to heat
GO175_RS01510	COG0564	pseudouridine synthase activity
GO175_RS01515	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GO175_RS01520	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GO175_RS01525	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GO175_RS01530	COG1605	Chorismate mutase
GO175_RS01530	COG0077	Prephenate dehydratase
GO175_RS01535	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GO175_RS01540	COG5001	Diguanylate cyclase
GO175_RS01545	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GO175_RS01560	COG0488	(ABC) transporter
GO175_RS01570	COG0287	Prephenate dehydrogenase
GO175_RS01570	COG1605	Chorismate mutase
GO175_RS01575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO175_RS01580	COG3275	phosphorelay sensor kinase activity
GO175_RS01585	COG3279	Response regulator of the LytR AlgR family
GO175_RS01595	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GO175_RS01600	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GO175_RS01615	COG1966	Carbon starvation protein
GO175_RS01620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GO175_RS01625	COG1047	Peptidyl-prolyl cis-trans
GO175_RS01630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GO175_RS01635	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GO175_RS01640	COG0196	riboflavin kinase activity
GO175_RS01645	COG0728	peptidoglycan biosynthetic process
GO175_RS01655	COG0640	Transcriptional regulator
GO175_RS01660	COG0583	DNA-binding transcription factor activity
GO175_RS01665	COG1283	sodium-dependent phosphate transmembrane transporter activity
GO175_RS01680	COG0730	response to heat
GO175_RS01690	COG0494	nUDIX hydrolase
GO175_RS01695	COG3066	DNA modification
GO175_RS01705	COG0667	Aldo Keto reductase
GO175_RS01715	COG2204	response regulator
GO175_RS01740	COG0513	Belongs to the DEAD box helicase family
GO175_RS01745	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GO175_RS01765	COG3153	acetyltransferase
GO175_RS01790	COG0534	Mate efflux family protein
GO175_RS01815	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GO175_RS01820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GO175_RS01830	COG0195	Participates in both transcription termination and antitermination
GO175_RS01835	COG0779	Required for maturation of 30S ribosomal subunits
GO175_RS01850	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GO175_RS01855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GO175_RS01860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GO175_RS01865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GO175_RS01875	COG1534	Rna-binding protein
GO175_RS01880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GO175_RS01885	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GO175_RS01890	COG2027	D-alanyl-D-alanine carboxypeptidase
GO175_RS01895	COG2239	Acts as a magnesium transporter
GO175_RS01905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GO175_RS01910	COG0739	heme binding
GO175_RS01925	COG0316	Belongs to the HesB IscA family
GO175_RS01930	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GO175_RS01940	COG0628	permease
GO175_RS01955	COG0747	negative chemotaxis
GO175_RS01965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO175_RS01970	COG0444	Belongs to the ABC transporter superfamily
GO175_RS01975	COG4608	Belongs to the ABC transporter superfamily
GO175_RS01985	COG2971	BadF BadG BcrA BcrD
GO175_RS02000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GO175_RS02005	COG3842	ATPase activity
GO175_RS02015	COG1840	ABC-type Fe3 transport system, periplasmic component
GO175_RS02020	COG0004	ammonium transporteR
GO175_RS02025	COG0347	Belongs to the P(II) protein family
GO175_RS02030	COG3112	Uncharacterised protein family (UPF0231)
GO175_RS02035	COG1049	propionate catabolic process, 2-methylcitrate cycle
GO175_RS02040	COG1752	Esterase of the alpha-beta hydrolase superfamily
GO175_RS02045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GO175_RS02050	COG1643	Atp-dependent helicase
GO175_RS02055	COG1489	DNA binding
GO175_RS02060	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GO175_RS02065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GO175_RS02075	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GO175_RS02080	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GO175_RS02085	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GO175_RS02090	COG0842	Transport permease protein
GO175_RS02095	COG1131	(ABC) transporter
GO175_RS02100	COG0288	reversible hydration of carbon dioxide
GO175_RS02115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GO175_RS02120	COG0508	dehydrogenase complex catalyzes the overall conversion of
GO175_RS02125	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GO175_RS02130	COG2186	Transcriptional regulator
GO175_RS02135	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GO175_RS02140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GO175_RS02145	COG4974	Belongs to the 'phage' integrase family
GO175_RS02150	COG0716	FMN binding
GO175_RS02175	COG1459	type II secretion system
GO175_RS02190	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GO175_RS02195	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GO175_RS02200	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GO175_RS02205	COG0187	DNA topoisomerase II activity
GO175_RS02210	COG3150	esterase
GO175_RS02220	COG3151	Protein conserved in bacteria
GO175_RS02225	COG0494	nUDIX hydrolase
GO175_RS02230	COG1538	Outer membrane efflux protein
GO175_RS02235	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GO175_RS02235	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GO175_RS02240	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GO175_RS02250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GO175_RS02255	COG3025	triphosphatase activity
GO175_RS02260	COG1392	Phosphate transport regulator
GO175_RS02265	COG0306	phosphate transporter
GO175_RS02270	COG4991	sh3 domain protein
GO175_RS02280	COG3409	Peptidoglycan-binding domain 1 protein
GO175_RS02280	COG3267	Type II secretory pathway component ExeA
GO175_RS02285	COG0617	tRNA 3'-terminal CCA addition
GO175_RS02290	COG0148	phosphopyruvate hydratase activity
GO175_RS02295	COG0504	CTP synthase activity
GO175_RS02300	COG3956	TIGRFAM MazG family protein
GO175_RS02305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GO175_RS02310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GO175_RS02320	COG0736	holo-[acyl-carrier-protein] synthase activity
GO175_RS02325	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GO175_RS02330	COG1381	Involved in DNA repair and RecF pathway recombination
GO175_RS02335	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GO175_RS02340	COG0571	ribonuclease III activity
GO175_RS02345	COG0681	Belongs to the peptidase S26 family
GO175_RS02350	COG0481	GTPase activity
GO175_RS02355	COG3086	response to oxidative stress
GO175_RS02370	COG1595	DNA-templated transcription, initiation
GO175_RS02375	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GO175_RS02385	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GO175_RS02390	COG0354	folic acid binding
GO175_RS02405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO175_RS02410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO175_RS02420	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GO175_RS02430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GO175_RS02440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GO175_RS02445	COG0440	acetolactate synthase activity
GO175_RS02450	COG0028	Belongs to the TPP enzyme family
GO175_RS02455	COG1022	Amp-dependent synthetase and ligase
GO175_RS02460	COG0583	DNA-binding transcription factor activity
GO175_RS02480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GO175_RS02485	COG0473	3-isopropylmalate dehydrogenase activity
GO175_RS02490	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GO175_RS02540	COG3437	response regulator, receiver
GO175_RS02550	COG2203	Gaf domain
GO175_RS02550	COG2199	diguanylate cyclase activity
GO175_RS02550	COG2200	EAL domain
GO175_RS02565	COG1280	lysine exporter protein (LysE YggA)
GO175_RS02570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GO175_RS02575	COG1279	arginine transmembrane transporter activity
GO175_RS02625	COG2916	Histone family protein nucleoid-structuring protein H-NS
GO175_RS02630	COG3706	GGDEF domain
GO175_RS02630	COG0745	RESPONSE REGULATOR receiver
GO175_RS02695	COG3706	GGDEF domain
GO175_RS02705	COG0795	lipopolysaccharide-transporting ATPase activity
GO175_RS02710	COG0795	lipopolysaccharide-transporting ATPase activity
GO175_RS02725	COG0525	valine-tRNA ligase activity
GO175_RS02730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GO175_RS02735	COG0564	pseudouridine synthase activity
GO175_RS02745	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GO175_RS02755	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GO175_RS02760	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GO175_RS02765	COG0540	Belongs to the ATCase OTCase family
GO175_RS02770	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GO175_RS02775	COG0251	oxidation-reduction process
GO175_RS02780	COG0204	Acyl-transferase
GO175_RS02785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GO175_RS02790	COG5007	Belongs to the BolA IbaG family
GO175_RS02795	COG3113	response to antibiotic
GO175_RS02800	COG2854	intermembrane phospholipid transfer
GO175_RS02805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GO175_RS02810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GO175_RS02815	COG1127	ABC transporter
GO175_RS02825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GO175_RS02825	COG0517	IMP dehydrogenase activity
GO175_RS02830	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GO175_RS02840	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GO175_RS02845	COG1137	ATPase activity
GO175_RS02855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GO175_RS02860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO175_RS02870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO175_RS02875	COG2239	Acts as a magnesium transporter
GO175_RS02880	COG0312	modulator of DNA gyrase
GO175_RS02885	COG3028	Belongs to the UPF0307 family
GO175_RS02890	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GO175_RS02895	COG1178	ABC-type Fe3 transport system permease component
GO175_RS02900	COG4143	(ABC) transporter
GO175_RS02905	COG0163	prenyltransferase activity
GO175_RS02910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GO175_RS02915	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GO175_RS02920	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GO175_RS02925	COG2105	PFAM AIG2 family protein
GO175_RS02935	COG0729	surface antigen
GO175_RS02940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GO175_RS02945	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GO175_RS02960	COG0577	efflux transmembrane transporter activity
GO175_RS02960	COG1136	(ABC) transporter
GO175_RS02980	COG0529	Catalyzes the synthesis of activated sulfate
GO175_RS02985	COG0490	domain, Protein
GO175_RS02985	COG0471	metal ion transport
GO175_RS02990	COG2895	sulfate adenylyltransferase (ATP) activity
GO175_RS02995	COG0175	sulfate reduction
GO175_RS03000	COG1648	precorrin-2 dehydrogenase activity
GO175_RS03000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GO175_RS03005	COG0737	Belongs to the 5'-nucleotidase family
GO175_RS03015	COG0513	Belongs to the DEAD box helicase family
GO175_RS03020	COG2153	protein acetylation
GO175_RS03025	COG0697	spore germination
GO175_RS03030	COG3061	Opacity-associated protein A
GO175_RS03035	COG0545	Peptidyl-prolyl cis-trans isomerase
GO175_RS03045	COG0203	ribosomal protein L17
GO175_RS03050	COG0202	RNA polymerase activity
GO175_RS03055	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GO175_RS03060	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GO175_RS03075	COG0201	protein transport
GO175_RS03085	COG1841	ribosomal large subunit assembly
GO175_RS03095	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GO175_RS03100	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GO175_RS03105	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GO175_RS03110	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GO175_RS03115	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GO175_RS03120	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GO175_RS03125	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GO175_RS03135	COG0255	Belongs to the universal ribosomal protein uL29 family
GO175_RS03150	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GO175_RS03155	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GO175_RS03165	COG0089	rRNA binding
GO175_RS03170	COG0088	Forms part of the polypeptide exit tunnel
GO175_RS03175	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GO175_RS03180	COG0051	transcription antitermination factor activity, RNA binding
GO175_RS03185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GO175_RS03190	COG0557	exoribonuclease II activity
GO175_RS03195	COG3083	sulfuric ester hydrolase activity
GO175_RS03200	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GO175_RS03205	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GO175_RS03215	COG1047	Peptidyl-prolyl cis-trans
GO175_RS03220	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GO175_RS03230	COG2249	NAD(P)H dehydrogenase (quinone) activity
GO175_RS03235	COG0488	(ABC) transporter
GO175_RS03245	COG0429	hydrolase of the alpha beta-hydrolase fold
GO175_RS03255	COG3954	Phosphoribulokinase
GO175_RS03260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GO175_RS03270	COG1012	belongs to the aldehyde dehydrogenase family
GO175_RS03280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GO175_RS03290	COG0446	pyridine nucleotide-disulphide oxidoreductase
GO175_RS03300	COG0180	Tryptophanyl-tRNA synthetase
GO175_RS03310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GO175_RS03315	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GO175_RS03325	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GO175_RS03360	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GO175_RS03370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GO175_RS03370	COG0678	peroxiredoxin activity
GO175_RS03380	COG0165	Argininosuccinate lyase
GO175_RS03380	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GO175_RS03390	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GO175_RS03395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GO175_RS03400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GO175_RS03405	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GO175_RS03410	COG1695	Transcriptional regulator
GO175_RS03415	COG1045	serine acetyltransferase
GO175_RS03420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GO175_RS03425	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GO175_RS03430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GO175_RS03435	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GO175_RS03440	COG1053	succinate dehydrogenase
GO175_RS03445	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GO175_RS03450	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GO175_RS03455	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GO175_RS03460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GO175_RS03465	COG1509	lysine 2,3-aminomutase activity
GO175_RS03470	COG1285	pathogenesis
GO175_RS03480	COG1119	ATPase activity
GO175_RS03485	COG0459	protein refolding
GO175_RS03490	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GO175_RS03515	COG0149	triose-phosphate isomerase activity
GO175_RS03525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GO175_RS03530	COG1575	Belongs to the MenA family. Type 1 subfamily
GO175_RS03535	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GO175_RS03540	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GO175_RS03550	COG1609	Transcriptional regulator
GO175_RS03555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GO175_RS03560	COG0254	rRNA binding
GO175_RS03565	COG0281	malic enzyme
GO175_RS03575	COG0626	cystathionine gamma-synthase activity
GO175_RS03580	COG0527	aspartate kinase activity
GO175_RS03580	COG0460	homoserine dehydrogenase
GO175_RS03585	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GO175_RS03595	COG1494	fructose-1,6-bisphosphatase
GO175_RS03600	COG0205	6-phosphofructokinase activity
GO175_RS03605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GO175_RS03615	COG0745	RESPONSE REGULATOR receiver
GO175_RS03620	COG2205	protein histidine kinase activity
GO175_RS03625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GO175_RS03630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GO175_RS03635	COG3030	protein affecting phage T7 exclusion by the F plasmid
GO175_RS03640	COG3706	GGDEF domain
GO175_RS03645	COG1027	Aspartate ammonia-lyase
GO175_RS03650	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GO175_RS03655	COG1288	antiporter activity
GO175_RS03670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GO175_RS03680	COG0540	Belongs to the ATCase OTCase family
GO175_RS03685	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GO175_RS03695	COG4232	protein-disulfide reductase activity
GO175_RS03705	COG3263	regulation of cellular component size
GO175_RS03715	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GO175_RS03720	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GO175_RS03725	COG0194	GDP metabolic process
GO175_RS03735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GO175_RS03740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GO175_RS03745	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GO175_RS03750	COG2233	PERMEase
GO175_RS03755	COG2205	protein histidine kinase activity
GO175_RS03760	COG0745	RESPONSE REGULATOR receiver
GO175_RS03765	COG0800	Aldolase
GO175_RS03770	COG2610	gluconate transmembrane transporter activity
GO175_RS03775	COG3265	gluconokinase activity
GO175_RS03780	COG0129	dihydroxy-acid dehydratase activity
GO175_RS03785	COG1609	Transcriptional regulator
GO175_RS03790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GO175_RS03800	COG2183	response to ionizing radiation
GO175_RS03815	COG1040	competence protein
GO175_RS03820	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GO175_RS03820	COG0316	Belongs to the HesB IscA family
GO175_RS03825	COG0494	nUDIX hydrolase
GO175_RS03830	COG1218	3'(2'),5'-bisphosphate nucleotidase
GO175_RS03840	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GO175_RS03845	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GO175_RS03850	COG3156	type II secretion system protein K
GO175_RS03855	COG4795	General secretion pathway protein
GO175_RS03860	COG2165	general secretion pathway protein
GO175_RS03865	COG2165	general secretion pathway protein
GO175_RS03870	COG2165	general secretion pathway protein
GO175_RS03875	COG1459	type II secretion system
GO175_RS03880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GO175_RS03890	COG3031	protein transport across the cell outer membrane
GO175_RS03895	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GO175_RS03900	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GO175_RS03905	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GO175_RS03910	COG2982	Protein involved in outer membrane biogenesis
GO175_RS03920	COG1490	D-aminoacyl-tRNA deacylase activity
GO175_RS03945	COG0174	glutamine synthetase
GO175_RS03955	COG3852	Histidine kinase
GO175_RS03960	COG2204	response regulator
GO175_RS03965	COG3300	MHYT domain
GO175_RS03965	COG5001	Diguanylate cyclase
GO175_RS03970	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GO175_RS04030	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GO175_RS04045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GO175_RS04065	COG0534	Mate efflux family protein
GO175_RS04075	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GO175_RS04080	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GO175_RS04085	COG2937	Belongs to the GPAT DAPAT family
GO175_RS04090	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GO175_RS04095	COG3161	chorismate lyase activity
GO175_RS04100	COG1580	Controls the rotational direction of flagella during chemotaxis
GO175_RS04105	COG0705	Rhomboid family
GO175_RS04115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GO175_RS04120	COG2177	Part of the ABC transporter FtsEX involved in
GO175_RS04125	COG2884	Cell division ATP-binding protein ftsE
GO175_RS04130	COG0552	protein localization to endoplasmic reticulum
GO175_RS04135	COG0742	ribosomal rna small subunit methyltransferase
GO175_RS04145	COG2095	MarC family integral membrane protein
GO175_RS04175	COG0783	Belongs to the Dps family
GO175_RS04190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO175_RS04195	COG0640	Transcriptional regulator
GO175_RS04200	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GO175_RS04205	COG1280	lysine exporter protein (LysE YggA)
GO175_RS04210	COG2267	carboxylic ester hydrolase activity
GO175_RS04215	COG0561	phosphatase activity
GO175_RS04235	COG2199	diguanylate cyclase activity
GO175_RS04235	COG2200	EAL domain
GO175_RS04235	COG3287	FIST C domain
GO175_RS04240	COG1011	Hydrolase
GO175_RS04245	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GO175_RS04255	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GO175_RS04260	COG0019	diaminopimelate decarboxylase activity
GO175_RS04275	COG3072	Adenylate cyclase
GO175_RS04290	COG2959	enzyme of heme biosynthesis
GO175_RS04295	COG3071	HemY protein
GO175_RS04300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GO175_RS04325	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GO175_RS04330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GO175_RS04330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GO175_RS04345	COG0084	hydrolase, TatD family'
GO175_RS04350	COG0805	protein transport
GO175_RS04355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GO175_RS04365	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GO175_RS04370	COG3165	ubiquinone biosynthetic process from chorismate
GO175_RS04375	COG2226	methyltransferase
GO175_RS04380	COG1322	Protein conserved in bacteria
GO175_RS04405	COG2160	L-arabinose isomerase activity
GO175_RS04410	COG0235	Class ii aldolase
GO175_RS04415	COG1069	ribulokinase activity
GO175_RS04420	COG1879	ABC-type sugar transport system periplasmic component
GO175_RS04425	COG1129	ABC transporter
GO175_RS04430	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO175_RS04435	COG2081	HI0933 family
GO175_RS04445	COG1528	Iron-storage protein
GO175_RS04450	COG0589	response to stress
GO175_RS04465	COG0742	ribosomal rna small subunit methyltransferase
GO175_RS04470	COG5001	Diguanylate cyclase
GO175_RS04470	COG5002	protein histidine kinase activity
GO175_RS04475	COG1522	sequence-specific DNA binding
GO175_RS04495	COG0006	proline dipeptidase activity
GO175_RS04495	COG0006	proline dipeptidase activity
GO175_RS04525	COG0517	IMP dehydrogenase activity
GO175_RS04525	COG4175	Glycine betaine
GO175_RS04540	COG2022	thiamine diphosphate biosynthetic process
GO175_RS04540	COG2104	thiamine diphosphate biosynthetic process
GO175_RS04545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GO175_RS04555	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GO175_RS04560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GO175_RS04565	COG2132	Multicopper oxidase
GO175_RS04620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GO175_RS04625	COG1739	Uncharacterized protein family UPF0029
GO175_RS04635	COG0183	Belongs to the thiolase family
GO175_RS04640	COG0583	DNA-binding transcription factor activity
GO175_RS04645	COG2814	Major facilitator Superfamily
GO175_RS04650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO175_RS04655	COG0765	amino acid transport
GO175_RS04665	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GO175_RS04670	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GO175_RS04675	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GO175_RS04685	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GO175_RS04690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GO175_RS04700	COG0356	it plays a direct role in the translocation of protons across the membrane
GO175_RS04705	COG3312	ion transport
GO175_RS04710	COG1475	DNA binding
GO175_RS04715	COG1192	Involved in chromosome partitioning
GO175_RS04720	COG0357	Ribosomal RNA small subunit methyltransferase G
GO175_RS04725	COG0445	tRNA wobble uridine modification
GO175_RS04730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GO175_RS04735	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GO175_RS04740	COG0706	membrane insertase activity
GO175_RS04745	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GO175_RS04755	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GO175_RS04760	COG1126	abc transporter atp-binding protein
GO175_RS04775	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GO175_RS04780	COG0592	DNA-directed DNA polymerase activity
GO175_RS04785	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GO175_RS04790	COG0187	DNA topoisomerase II activity
GO175_RS04795	COG0071	Belongs to the small heat shock protein (HSP20) family
GO175_RS04800	COG3977	Valine--pyruvate aminotransferase
GO175_RS04805	COG0751	glycine-tRNA ligase activity
GO175_RS04810	COG0752	glycyl-tRNA synthetase alpha subunit
GO175_RS04815	COG2119	membrane
GO175_RS04840	COG0604	alcohol dehydrogenase
GO175_RS04855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GO175_RS04860	COG3978	acetolactate synthase activity
GO175_RS04870	COG0606	chelatase, subunit chli
GO175_RS04875	COG0204	Acyl-transferase
GO175_RS04880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GO175_RS04885	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GO175_RS04895	COG3084	Protein conserved in bacteria
GO175_RS04905	COG4326	sporulation control protein
GO175_RS04910	COG1272	protein, Hemolysin III
GO175_RS04920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GO175_RS04925	COG0569	domain protein
GO175_RS04930	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GO175_RS04930	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GO175_RS04940	COG0242	peptide deformylase activity
GO175_RS04945	COG1652	LysM domain
GO175_RS04950	COG0758	DNA mediated transformation
GO175_RS04955	COG2922	Belongs to the Smg family
GO175_RS04960	COG0551	DNA topoisomerase type I activity
GO175_RS04965	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GO175_RS04980	COG0408	coproporphyrinogen oxidase activity
GO175_RS04985	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GO175_RS04995	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GO175_RS05040	COG0583	DNA-binding transcription factor activity
GO175_RS05050	COG2960	long-chain fatty acid transporting porin activity
GO175_RS05055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO175_RS05060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO175_RS05070	COG0210	DNA helicase
GO175_RS05105	COG4172	Belongs to the ABC transporter superfamily
GO175_RS05110	COG0747	negative chemotaxis
GO175_RS05120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO175_RS05130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO175_RS05135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO175_RS05150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GO175_RS05155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GO175_RS05190	COG0210	DNA helicase
GO175_RS05195	COG0405	Gamma-glutamyltransferase
GO175_RS05200	COG1280	lysine exporter protein (LysE YggA)
GO175_RS05210	COG2962	Rard protein
GO175_RS05215	COG0514	ATP-dependent DNA helicase (RecQ)
GO175_RS05230	COG1132	(ABC) transporter
GO175_RS05235	COG1120	ATPase activity
GO175_RS05240	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GO175_RS05260	COG1561	YicC-like family, N-terminal region
GO175_RS05265	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GO175_RS05270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GO175_RS05275	COG1560	Kdo2-lipid A biosynthetic process
GO175_RS05280	COG1309	transcriptional regulator
GO175_RS05285	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GO175_RS05305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GO175_RS05315	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GO175_RS05330	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GO175_RS05335	COG0438	transferase activity, transferring glycosyl groups
GO175_RS05340	COG0438	transferase activity, transferring glycosyl groups
GO175_RS05345	COG0463	Glycosyl transferase, family 2
GO175_RS05350	COG0859	PFAM glycosyl transferase family 9
GO175_RS05360	COG0438	transferase activity, transferring glycosyl groups
GO175_RS05365	COG1519	Transferase
GO175_RS05370	COG0859	PFAM glycosyl transferase family 9
GO175_RS05375	COG0859	PFAM glycosyl transferase family 9
GO175_RS05385	COG1560	Kdo2-lipid A biosynthetic process
GO175_RS05395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GO175_RS05400	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GO175_RS05490	COG0438	transferase activity, transferring glycosyl groups
GO175_RS05495	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GO175_RS05500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GO175_RS05505	COG1051	belongs to the nudix hydrolase family
GO175_RS05530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GO175_RS05540	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GO175_RS05545	COG1573	uracil-dna glycosylase
GO175_RS05550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GO175_RS05555	COG3068	Protein conserved in bacteria
GO175_RS05560	COG0668	transmembrane transport
GO175_RS05565	COG1253	flavin adenine dinucleotide binding
GO175_RS05570	COG0776	regulation of translation
GO175_RS05580	COG0151	Belongs to the GarS family
GO175_RS05585	COG0138	bifunctional purine biosynthesis protein purh
GO175_RS05595	COG0789	Transcriptional regulator
GO175_RS05600	COG1940	carbohydrate kinase activity
GO175_RS05610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO175_RS05610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO175_RS05610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO175_RS05615	COG2207	Transcriptional regulator
GO175_RS05625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO175_RS05630	COG0840	transmembrane signaling receptor activity
GO175_RS05635	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GO175_RS05640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GO175_RS05645	COG2264	protein methyltransferase activity
GO175_RS05650	COG0439	Biotin carboxylase
GO175_RS05655	COG0511	ligase activity, forming carbon-carbon bonds
GO175_RS05660	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GO175_RS05665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GO175_RS05680	COG2814	Major facilitator Superfamily
GO175_RS05685	COG2205	protein histidine kinase activity
GO175_RS05685	COG2198	Histidine kinase
GO175_RS05685	COG0784	Response regulator, receiver
GO175_RS05685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO175_RS05690	COG0248	Ppx GppA phosphatase
GO175_RS05695	COG0513	Belongs to the DEAD box helicase family
GO175_RS05700	COG3118	belongs to the thioredoxin family
GO175_RS05705	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GO175_RS05715	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GO175_RS05785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GO175_RS05795	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GO175_RS05805	COG1072	(Pantothenic acid kinase))
GO175_RS05835	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GO175_RS05840	COG0250	Participates in transcription elongation, termination and antitermination
GO175_RS05845	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GO175_RS05850	COG0081	regulation of translation
GO175_RS05855	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GO175_RS05865	COG0085	RNA polymerase activity
GO175_RS05870	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GO175_RS05875	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GO175_RS05900	COG4942	peptidase
GO175_RS05905	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GO175_RS05920	COG0490	domain, Protein
GO175_RS05920	COG0471	metal ion transport
GO175_RS05925	COG0688	phosphatidylethanolamine metabolic process
GO175_RS05930	COG1162	GTPase activity
GO175_RS05985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GO175_RS05990	COG0802	atpase or kinase
GO175_RS06000	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GO175_RS06005	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GO175_RS06010	COG1923	regulation of RNA biosynthetic process
GO175_RS06015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GO175_RS06020	COG0330	HflC and HflK could
GO175_RS06025	COG0330	HflC and HflK could
GO175_RS06030	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GO175_RS06035	COG2900	Belongs to the SlyX family
GO175_RS06045	COG0545	Peptidyl-prolyl cis-trans isomerase
GO175_RS06050	COG2964	Protein conserved in bacteria
GO175_RS06060	COG2923	Belongs to the DsrF TusC family
GO175_RS06065	COG2168	tRNA wobble position uridine thiolation
GO175_RS06075	COG0049	tRNA binding
GO175_RS06080	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GO175_RS06090	COG2906	2 iron, 2 sulfur cluster binding
GO175_RS06100	COG0360	Binds together with S18 to 16S ribosomal RNA
GO175_RS06105	COG2965	DNA replication, synthesis of RNA primer
GO175_RS06115	COG0359	binds to the 23S rRNA
GO175_RS06125	COG0305	Participates in initiation and elongation during chromosome replication
GO175_RS06130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GO175_RS06135	COG0432	Pfam Uncharacterised protein family UPF0047
GO175_RS06140	COG0166	Belongs to the GPI family
GO175_RS06150	COG0735	belongs to the Fur family
GO175_RS06155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GO175_RS06185	COG0175	sulfate reduction
GO175_RS06250	COG1410	methionine synthase
GO175_RS06250	COG0646	methionine synthase
GO175_RS06255	COG0527	aspartate kinase activity
GO175_RS06260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GO175_RS06270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GO175_RS06285	COG0629	single-stranded DNA binding
GO175_RS06290	COG2199	diguanylate cyclase activity
GO175_RS06290	COG2200	EAL domain
GO175_RS06315	COG3267	Type II secretory pathway component ExeA
GO175_RS06315	COG3409	Peptidoglycan-binding domain 1 protein
GO175_RS06325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GO175_RS06375	COG1077	Cell shape determining protein MreB Mrl
GO175_RS06380	COG1792	Involved in formation and maintenance of cell shape
GO175_RS06385	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GO175_RS06390	COG0424	maF-like protein
GO175_RS06395	COG1530	ribonuclease E activity
GO175_RS06400	COG3164	Protein of unknown function
GO175_RS06410	COG0312	modulator of DNA gyrase
GO175_RS06430	COG0589	response to stress
GO175_RS06450	COG0039	L-malate dehydrogenase activity
GO175_RS06460	COG0142	geranyltranstransferase activity
GO175_RS06465	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GO175_RS06470	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GO175_RS06475	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GO175_RS06480	COG2966	Psort location CytoplasmicMembrane, score
GO175_RS06485	COG3610	response to peptide
GO175_RS06500	COG2967	ApaG domain
GO175_RS06515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GO175_RS06520	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GO175_RS06525	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GO175_RS06580	COG0741	lytic transglycosylase activity
GO175_RS06585	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GO175_RS06590	COG1194	a g-specific adenine glycosylase
GO175_RS06595	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GO175_RS06600	COG2066	Belongs to the glutaminase family
GO175_RS06605	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GO175_RS06610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GO175_RS06625	COG1872	DUF167
GO175_RS06630	COG0762	integral membrane protein
GO175_RS06635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GO175_RS06640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GO175_RS06655	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GO175_RS06660	COG1678	Uncharacterized ACR, COG1678
GO175_RS06665	COG0189	ligase activity
GO175_RS06670	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GO175_RS06675	COG2356	endonuclease I
GO175_RS06695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GO175_RS06700	COG0583	DNA-binding transcription factor activity
GO175_RS06705	COG4771	TonB-dependent receptor
GO175_RS06710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO175_RS06715	COG0126	phosphoglycerate kinase activity
GO175_RS06720	COG0191	fructose-bisphosphate aldolase activity
GO175_RS06725	COG0668	transmembrane transport
GO175_RS06750	COG3706	GGDEF domain
GO175_RS06755	COG0469	pyruvate kinase activity
GO175_RS06760	COG1349	DNA-binding transcription factor activity
GO175_RS06765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO175_RS06770	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GO175_RS06785	COG2239	Acts as a magnesium transporter
GO175_RS06825	COG0328	RNA-DNA hybrid ribonuclease activity
GO175_RS06880	COG0789	Transcriptional regulator
GO175_RS06885	COG2217	Heavy metal translocating P-type atpase
GO175_RS06920	COG5002	protein histidine kinase activity
GO175_RS06925	COG4580	involved in the transport of maltose and maltodextrins
GO175_RS06940	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO175_RS06990	COG2003	Belongs to the UPF0758 family
GO175_RS07010	COG0582	viral genome integration into host DNA
GO175_RS07020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GO175_RS07030	COG1610	YqeY-like protein
GO175_RS07035	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GO175_RS07040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GO175_RS07050	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GO175_RS07055	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GO175_RS07060	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GO175_RS07070	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GO175_RS07075	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GO175_RS07085	COG0585	pseudouridine synthase activity
GO175_RS07090	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GO175_RS07100	COG4942	peptidase
GO175_RS07100	COG1388	LysM domain
GO175_RS07105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GO175_RS07110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GO175_RS07115	COG1546	Belongs to the CinA family
GO175_RS07120	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GO175_RS07130	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GO175_RS07135	COG0527	aspartate kinase activity
GO175_RS07185	COG3630	sodium ion export across plasma membrane
GO175_RS07190	COG0511	ligase activity, forming carbon-carbon bonds
GO175_RS07190	COG5016	pyruvate
GO175_RS07195	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GO175_RS07200	COG1063	alcohol dehydrogenase
GO175_RS07205	COG1238	metal cluster binding
GO175_RS07210	COG0612	Peptidase, M16
GO175_RS07225	COG1854	S-ribosylhomocysteine lyase activity
GO175_RS07230	COG4536	flavin adenine dinucleotide binding
GO175_RS07235	COG4137	Cytochrome C assembly protein
GO175_RS07240	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GO175_RS07250	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GO175_RS07260	COG0335	large ribosomal subunit rRNA binding
GO175_RS07265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GO175_RS07270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GO175_RS07275	COG3105	Protein conserved in bacteria
GO175_RS07280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GO175_RS07290	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GO175_RS07295	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO175_RS07300	COG0723	plastoquinol--plastocyanin reductase activity
GO175_RS07305	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GO175_RS07310	COG2857	Cytochrome c1
GO175_RS07315	COG0625	glutathione transferase activity
GO175_RS07320	COG2969	positive regulation of protein catabolic process
GO175_RS07325	COG2823	Periplasmic or secreted lipoprotein
GO175_RS07330	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GO175_RS07335	COG0792	nuclease activity
GO175_RS07340	COG3107	peptidoglycan biosynthetic process
GO175_RS07345	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GO175_RS07355	COG0275	rRNA processing
GO175_RS07360	COG3116	cell division
GO175_RS07365	COG0768	penicillin binding
GO175_RS07370	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GO175_RS07375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GO175_RS07380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GO175_RS07385	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GO175_RS07390	COG0772	Belongs to the SEDS family
GO175_RS07395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GO175_RS07400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GO175_RS07405	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GO175_RS07410	COG0849	cell division
GO175_RS07415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GO175_RS07420	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GO175_RS07430	COG0653	protein targeting
GO175_RS07435	COG0494	nUDIX hydrolase
GO175_RS07445	COG0505	Belongs to the CarA family
GO175_RS07455	COG0730	response to heat
GO175_RS07460	COG0583	DNA-binding transcription factor activity
GO175_RS07480	COG2860	membrane
GO175_RS07485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GO175_RS07505	COG0493	'glutamate synthase
GO175_RS07510	COG0067	glutamate synthase
GO175_RS07510	COG0070	glutamate synthase
GO175_RS07510	COG0069	glutamate synthase activity
GO175_RS07520	COG0069	glutamate synthase activity
GO175_RS07520	COG0067	glutamate synthase
GO175_RS07520	COG0070	glutamate synthase
GO175_RS07525	COG1242	4 iron, 4 sulfur cluster binding
GO175_RS07530	COG3706	GGDEF domain
GO175_RS07530	COG2203	Gaf domain
GO175_RS07530	COG4251	negative regulation of phosphorylation
GO175_RS07530	COG5001	Diguanylate cyclase
GO175_RS07535	COG5002	protein histidine kinase activity
GO175_RS07535	COG0784	Response regulator, receiver
GO175_RS07535	COG2198	Histidine kinase
GO175_RS07545	COG0745	RESPONSE REGULATOR receiver
GO175_RS07560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GO175_RS07575	COG0083	homoserine kinase activity
GO175_RS07580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GO175_RS07600	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GO175_RS07615	COG1115	amino acid carrier protein
GO175_RS07625	COG0084	hydrolase, TatD family'
GO175_RS07650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GO175_RS07655	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GO175_RS07660	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GO175_RS07665	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GO175_RS07670	COG0813	purine-nucleoside phosphorylase activity
GO175_RS07680	COG0560	Phosphoserine phosphatase
GO175_RS07690	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GO175_RS07695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GO175_RS07700	COG0583	DNA-binding transcription factor activity
GO175_RS07710	COG0583	DNA-binding transcription factor activity
GO175_RS07750	COG4964	Belongs to the GSP D family
GO175_RS07800	COG3437	response regulator, receiver
GO175_RS07800	COG0784	Response regulator, receiver
GO175_RS07805	COG2059	Chromate
GO175_RS07815	COG2017	converts alpha-aldose to the beta-anomer
GO175_RS07820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO175_RS07835	COG0569	domain protein
GO175_RS07835	COG0189	ligase activity
GO175_RS07850	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GO175_RS07855	COG2171	N-acyltransferase activity
GO175_RS07860	COG3141	response to X-ray
GO175_RS07865	COG0583	DNA-binding transcription factor activity
GO175_RS07875	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GO175_RS07880	COG1074	ATP-dependent DNA helicase activity
GO175_RS07885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GO175_RS07895	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GO175_RS07895	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GO175_RS07905	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GO175_RS07910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GO175_RS07915	COG2166	iron-sulfur cluster assembly
GO175_RS07925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GO175_RS07930	COG0693	protein deglycase activity
GO175_RS07935	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GO175_RS07940	COG3248	Nucleoside-binding outer membrane protein
GO175_RS07950	COG1595	DNA-templated transcription, initiation
GO175_RS07965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GO175_RS07975	COG2974	May be involved in recombination
GO175_RS07980	COG0745	RESPONSE REGULATOR receiver
GO175_RS07985	COG5002	protein histidine kinase activity
GO175_RS07995	COG0248	Ppx GppA phosphatase
GO175_RS08000	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GO175_RS08005	COG0573	inorganic phosphate transmembrane transporter activity
GO175_RS08010	COG0581	inorganic phosphate transmembrane transporter activity
GO175_RS08015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GO175_RS08020	COG0704	Plays a role in the regulation of phosphate uptake
GO175_RS08035	COG0450	alkyl hydroperoxide reductase
GO175_RS08040	COG0583	DNA-binding transcription factor activity
GO175_RS08045	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GO175_RS08055	COG0517	IMP dehydrogenase activity
GO175_RS08060	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GO175_RS08065	COG0343	queuine tRNA-ribosyltransferase activity
GO175_RS08070	COG1862	Preprotein translocase
GO175_RS08075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GO175_RS08080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GO175_RS08085	COG1335	isochorismatase
GO175_RS08090	COG0483	inositol monophosphate 1-phosphatase activity
GO175_RS08095	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GO175_RS08100	COG1959	2 iron, 2 sulfur cluster binding
GO175_RS08105	COG1104	cysteine desulfurase activity
GO175_RS08110	COG0822	iron-sulfur transferase activity
GO175_RS08125	COG0443	Heat shock 70 kDa protein
GO175_RS08130	COG0633	Ferredoxin
GO175_RS08135	COG2975	iron-sulfur cluster assembly
GO175_RS08140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GO175_RS08160	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GO175_RS08165	COG0124	histidyl-tRNA synthetase
GO175_RS08170	COG2976	Protein conserved in bacteria
GO175_RS08175	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GO175_RS08180	COG1160	GTP binding
GO175_RS08195	COG1570	exodeoxyribonuclease VII activity
GO175_RS08200	COG0517	IMP dehydrogenase activity
GO175_RS08200	COG0516	GMP reductase activity
GO175_RS08205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GO175_RS08205	COG0519	Catalyzes the synthesis of GMP from XMP
GO175_RS08210	COG0582	viral genome integration into host DNA
GO175_RS08220	COG1396	sequence-specific DNA binding
GO175_RS08310	COG1584	GPR1 FUN34 yaaH family protein
GO175_RS08325	COG1473	amidohydrolase
GO175_RS08335	COG1115	amino acid carrier protein
GO175_RS08340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GO175_RS08345	COG0583	DNA-binding transcription factor activity
GO175_RS08405	COG0582	viral genome integration into host DNA
GO175_RS08415	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GO175_RS08420	COG2867	negative regulation of translational initiation
GO175_RS08425	COG2914	Belongs to the UPF0125 (RnfH) family
GO175_RS08430	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GO175_RS08435	COG0497	DNA recombination
GO175_RS08440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GO175_RS08445	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GO175_RS08455	COG0443	Heat shock 70 kDa protein
GO175_RS08465	COG4969	Belongs to the N-Me-Phe pilin family
GO175_RS08490	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GO175_RS08495	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GO175_RS08500	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GO175_RS08505	COG0583	DNA-binding transcription factor activity
GO175_RS08510	COG0590	tRNA wobble adenosine to inosine editing
GO175_RS08515	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GO175_RS08540	COG0442	prolyl-tRNA aminoacylation
GO175_RS08545	COG1720	tRNA m6t6A37 methyltransferase activity
GO175_RS08550	COG0254	rRNA binding
GO175_RS08555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GO175_RS08560	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GO175_RS08565	COG1671	Belongs to the UPF0178 family
GO175_RS08590	COG3098	single-species biofilm formation
GO175_RS08595	COG0564	pseudouridine synthase activity
GO175_RS08600	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GO175_RS08605	COG0142	geranyltranstransferase activity
GO175_RS08615	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GO175_RS08625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GO175_RS08625	COG0301	tRNA thio-modification
GO175_RS08630	COG0583	DNA-binding transcription factor activity
GO175_RS08640	COG2363	Small membrane protein
GO175_RS08650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GO175_RS08660	COG3706	GGDEF domain
GO175_RS08660	COG0745	RESPONSE REGULATOR receiver
GO175_RS08670	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GO175_RS08670	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GO175_RS08680	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GO175_RS08685	COG1464	Belongs to the NlpA lipoprotein family
GO175_RS08690	COG2011	ABC-type metal ion transport system permease component
GO175_RS08695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GO175_RS08700	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GO175_RS08715	COG1263	PTS System
GO175_RS08715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO175_RS08720	COG0366	Alpha amylase catalytic
GO175_RS08725	COG2271	Major facilitator Superfamily
GO175_RS08730	COG3851	Histidine kinase
GO175_RS08735	COG2197	response regulator
GO175_RS08765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO175_RS08770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO175_RS08780	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GO175_RS08790	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GO175_RS08795	COG0321	lipoyl(octanoyl) transferase activity
GO175_RS08800	COG2921	Belongs to the UPF0250 family
GO175_RS08805	COG1686	Belongs to the peptidase S11 family
GO175_RS08810	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GO175_RS08815	COG0772	Belongs to the SEDS family
GO175_RS08820	COG0768	penicillin binding
GO175_RS08825	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GO175_RS08830	COG0799	negative regulation of ribosome biogenesis
GO175_RS08835	COG1466	dna polymerase III delta subunit
GO175_RS08840	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GO175_RS08850	COG2888	peptidyl-tyrosine sulfation
GO175_RS08855	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GO175_RS08860	COG4535	Mg2 and Co2 transporter CorC
GO175_RS08865	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GO175_RS08870	COG1702	phosphate starvation-inducible protein PhoH
GO175_RS08875	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GO175_RS08880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO175_RS08885	COG2190	(PTS) system
GO175_RS08895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO175_RS08905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GO175_RS08910	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GO175_RS08915	COG3115	cell septum assembly
GO175_RS08920	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GO175_RS08935	COG0789	Transcriptional regulator
GO175_RS08945	COG0330	HflC and HflK could
GO175_RS08950	COG3118	belongs to the thioredoxin family
GO175_RS08960	COG0300	oxidoreductase activity
GO175_RS08965	COG1090	epimerase
GO175_RS08990	COG0622	Phosphoesterase
GO175_RS09005	COG3710	Transcriptional regulator
GO175_RS09010	COG0326	Molecular chaperone. Has ATPase activity
GO175_RS09020	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GO175_RS09025	COG3104	oligopeptide transport
GO175_RS09035	COG0367	asparagine synthase
GO175_RS09040	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GO175_RS09040	COG4651	solute:proton antiporter activity
GO175_RS09045	COG1940	carbohydrate kinase activity
GO175_RS09045	COG1846	Transcriptional regulator
GO175_RS09050	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GO175_RS09055	COG1263	PTS System
GO175_RS09055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO175_RS09055	COG2190	(PTS) system
GO175_RS09060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GO175_RS09070	COG0101	tRNA pseudouridine synthase activity
GO175_RS09080	COG0285	dihydrofolate synthase activity
GO175_RS09085	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GO175_RS09090	COG1286	toxin biosynthetic process
GO175_RS09095	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GO175_RS09100	COG2056	Na+-H+ antiporter family
GO175_RS09105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GO175_RS09120	COG0346	lactoylglutathione lyase activity
GO175_RS09125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GO175_RS09130	COG4660	Part of a membrane complex involved in electron transport
GO175_RS09140	COG4658	electron transport chain
GO175_RS09145	COG4656	Part of a membrane complex involved in electron transport
GO175_RS09150	COG2878	Part of a membrane complex involved in electron transport
GO175_RS09155	COG4657	Part of a membrane complex involved in electron transport
GO175_RS09170	COG2204	response regulator
GO175_RS09175	COG2198	Histidine kinase
GO175_RS09180	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GO175_RS09185	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GO175_RS09190	COG0521	Mo-molybdopterin cofactor biosynthetic process
GO175_RS09195	COG0315	cyclic pyranopterin monophosphate synthase activity
GO175_RS09200	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GO175_RS09205	COG0314	molybdopterin synthase activity
GO175_RS09210	COG3706	GGDEF domain
GO175_RS09215	COG0517	IMP dehydrogenase activity
GO175_RS09215	COG0516	GMP reductase activity
GO175_RS09225	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GO175_RS09235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO175_RS09235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO175_RS09240	COG0489	protein tyrosine kinase activity
GO175_RS09245	COG0572	uridine kinase
GO175_RS09250	COG2982	Protein involved in outer membrane biogenesis
GO175_RS09255	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GO175_RS09270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GO175_RS09275	COG2067	long-chain fatty acid transport protein
GO175_RS09280	COG2067	long-chain fatty acid transport protein
GO175_RS09295	COG0183	Belongs to the thiolase family
GO175_RS09300	COG1024	Enoyl-CoA hydratase
GO175_RS09300	COG1250	3-hydroxyacyl-CoA dehydrogenase
GO175_RS09305	COG0778	Nitroreductase
GO175_RS09310	COG0583	DNA-binding transcription factor activity
GO175_RS09315	COG0745	RESPONSE REGULATOR receiver
GO175_RS09325	COG2832	Protein of unknown function (DUF454)
GO175_RS09330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GO175_RS09340	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GO175_RS09345	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GO175_RS09350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GO175_RS09460	COG4695	Portal protein
GO175_RS09605	COG2226	methyltransferase
GO175_RS09615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO175_RS09620	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GO175_RS09630	COG3139	Protein of unknown function (DUF1315)
GO175_RS09635	COG0252	asparaginase activity
GO175_RS09640	COG0616	signal peptide processing
GO175_RS09645	COG0446	pyridine nucleotide-disulphide oxidoreductase
GO175_RS09645	COG1902	pentaerythritol trinitrate reductase activity
GO175_RS09650	COG0788	formyltetrahydrofolate deformylase activity
GO175_RS09660	COG1199	ATP-dependent helicase activity
GO175_RS09665	COG1214	PFAM Peptidase M22, glycoprotease
GO175_RS09685	COG0318	PFAM AMP-dependent synthetase and ligase
GO175_RS09690	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GO175_RS09700	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GO175_RS09705	COG2894	cell division
GO175_RS09715	COG3100	YcgL domain-containing protein
GO175_RS09720	COG2951	lytic endotransglycosylase activity
GO175_RS09730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GO175_RS09735	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GO175_RS09795	COG3842	ATPase activity
GO175_RS09805	COG1840	ABC-type Fe3 transport system, periplasmic component
GO175_RS09810	COG2271	Major facilitator Superfamily
GO175_RS09815	COG3851	Histidine kinase
GO175_RS09820	COG2197	response regulator
GO175_RS09855	COG4589	Belongs to the CDS family
GO175_RS09865	COG1716	ATPase activity
GO175_RS09865	COG5001	Diguanylate cyclase
GO175_RS09875	COG3153	acetyltransferase
GO175_RS09875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GO175_RS09885	COG1760	l-serine dehydratase
GO175_RS09890	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GO175_RS09895	COG0745	RESPONSE REGULATOR receiver
GO175_RS09915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GO175_RS09920	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GO175_RS09925	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GO175_RS09930	COG2204	response regulator
GO175_RS09935	COG4191	Histidine kinase
GO175_RS09940	COG0544	peptidyl-prolyl cis-trans isomerase activity
GO175_RS09950	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GO175_RS09955	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GO175_RS09960	COG0776	regulation of translation
GO175_RS09965	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GO175_RS09970	COG1555	photosystem II stabilization
GO175_RS09975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GO175_RS09980	COG0539	negative regulation of cytoplasmic translation
GO175_RS09990	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GO175_RS09995	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GO175_RS10015	COG0583	DNA-binding transcription factor activity
GO175_RS10025	COG0686	Belongs to the AlaDH PNT family
GO175_RS10030	COG1522	sequence-specific DNA binding
GO175_RS10035	COG1674	ftsk spoiiie
GO175_RS10040	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GO175_RS10045	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GO175_RS10050	COG2186	Transcriptional regulator
GO175_RS10065	COG0537	adenosine 5'-monophosphoramidase activity
GO175_RS10095	COG1252	NADH dehydrogenase
GO175_RS10110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GO175_RS10120	COG4591	ABC-type transport system involved in lipoprotein release permease component
GO175_RS10125	COG1136	(ABC) transporter
GO175_RS10130	COG4591	ABC-type transport system involved in lipoprotein release permease component
GO175_RS10140	COG0658	competence protein
GO175_RS10140	COG2333	competence protein COMEC
GO175_RS10145	COG1132	(ABC) transporter
GO175_RS10160	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GO175_RS10165	COG2719	SpoVR family
GO175_RS10170	COG2718	Belongs to the UPF0229 family
GO175_RS10175	COG2766	serine protein kinase
GO175_RS10195	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GO175_RS10210	COG1882	Formate acetyltransferase
GO175_RS10230	COG4215	(ABC) transporter
GO175_RS10235	COG4160	amino acid transport
GO175_RS10240	COG0708	Exodeoxyribonuclease III
GO175_RS10245	COG0840	transmembrane signaling receptor activity
GO175_RS10255	COG3923	Primosomal replication protein n
GO175_RS10260	COG1199	ATP-dependent helicase activity
GO175_RS10265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GO175_RS10275	COG3012	SEC-C Motif Domain Protein
GO175_RS10280	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GO175_RS10285	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GO175_RS10290	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GO175_RS10295	COG0215	cysteine-tRNA ligase activity
GO175_RS10300	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GO175_RS10305	COG0632	four-way junction helicase activity
GO175_RS10310	COG2255	four-way junction helicase activity
GO175_RS10315	COG1271	oxidase subunit
GO175_RS10320	COG1294	oxidase, subunit
GO175_RS10325	COG4890	Cyd operon protein YbgT
GO175_RS10335	COG0824	Thioesterase
GO175_RS10340	COG0811	peptide transport
GO175_RS10360	COG2885	chlorophyll binding
GO175_RS10365	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GO175_RS10370	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GO175_RS10380	COG0784	Response regulator, receiver
GO175_RS10380	COG5002	protein histidine kinase activity
GO175_RS10395	COG1012	belongs to the aldehyde dehydrogenase family
GO175_RS10415	COG1960	acyl-CoA dehydrogenase activity
GO175_RS10420	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GO175_RS10430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GO175_RS10435	COG1979	alcohol dehydrogenase
GO175_RS10440	COG1737	Transcriptional regulator
GO175_RS10445	COG0076	glutamate decarboxylase activity
GO175_RS10455	COG2431	L-lysine efflux transmembrane transporter activity
GO175_RS10465	COG3070	regulator of competence-specific genes
GO175_RS10480	COG3852	Histidine kinase
GO175_RS10490	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GO175_RS10495	COG1032	radical SAM domain protein
GO175_RS10500	COG0488	(ABC) transporter
GO175_RS10520	COG0745	RESPONSE REGULATOR receiver
GO175_RS10525	COG5002	protein histidine kinase activity
GO175_RS10530	COG0346	lactoylglutathione lyase activity
GO175_RS10535	COG1794	racemase activity, acting on amino acids and derivatives
GO175_RS10550	COG0840	transmembrane signaling receptor activity
GO175_RS10555	COG2771	luxR family
GO175_RS10555	COG2200	EAL domain
GO175_RS10565	COG0625	glutathione transferase activity
GO175_RS10585	COG0612	Peptidase, M16
GO175_RS10600	COG0583	DNA-binding transcription factor activity
GO175_RS10605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GO175_RS10615	COG2350	Protein conserved in bacteria
GO175_RS10620	COG1607	acyl-coa hydrolase
GO175_RS10635	COG1301	dicarboxylic acid transport
GO175_RS10645	COG0133	tryptophan synthase activity
GO175_RS10650	COG0135	phosphoribosylanthranilate isomerase activity
GO175_RS10650	COG0134	indole-3-glycerol-phosphate synthase activity
GO175_RS10655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GO175_RS10660	COG0512	Glutamine amidotransferase of anthranilate synthase
GO175_RS10665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GO175_RS10675	COG0613	PHP domain protein
GO175_RS10680	COG0009	L-threonylcarbamoyladenylate synthase
GO175_RS10685	COG1187	pseudouridine synthase activity
GO175_RS10705	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GO175_RS10710	COG4988	ABC transporter
GO175_RS10715	COG0492	ferredoxin-NADP+ reductase activity
GO175_RS10735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GO175_RS10740	COG1454	alcohol dehydrogenase
GO175_RS10750	COG1414	Transcriptional regulator
GO175_RS10755	COG1414	Transcriptional regulator
GO175_RS10765	COG2949	membrane
GO175_RS10790	COG0640	Transcriptional regulator
GO175_RS10805	COG0583	DNA-binding transcription factor activity
GO175_RS10825	COG0281	malic enzyme
GO175_RS10830	COG1643	Atp-dependent helicase
GO175_RS10840	COG1757	Na H antiporter
GO175_RS10845	COG0174	glutamine synthetase
GO175_RS10850	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GO175_RS10855	COG1396	sequence-specific DNA binding
GO175_RS10855	COG1917	Cupin 2, conserved barrel domain protein
GO175_RS10860	COG1012	belongs to the aldehyde dehydrogenase family
GO175_RS10865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GO175_RS10875	COG2957	Belongs to the agmatine deiminase family
GO175_RS10885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GO175_RS10910	COG2885	chlorophyll binding
GO175_RS10925	COG0247	lactate metabolic process
GO175_RS10925	COG0277	FAD linked oxidase domain protein
GO175_RS10945	COG2986	histidine ammonia-lyase
GO175_RS10955	COG0010	Belongs to the arginase family
GO175_RS10960	COG1228	amidohydrolase
GO175_RS10980	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GO175_RS10990	COG5001	Diguanylate cyclase
GO175_RS10995	COG0417	DNA replication proofreading
GO175_RS11000	COG2197	response regulator
GO175_RS11005	COG0322	excinuclease ABC activity
GO175_RS11035	COG2133	pyrroloquinoline quinone binding
GO175_RS11040	COG0745	RESPONSE REGULATOR receiver
GO175_RS11040	COG3706	GGDEF domain
GO175_RS11055	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GO175_RS11060	COG0072	phenylalanine-tRNA ligase activity
GO175_RS11060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO175_RS11065	COG0776	regulation of translation
GO175_RS11075	COG0500	methyltransferase
GO175_RS11085	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GO175_RS11105	COG5001	Diguanylate cyclase
GO175_RS11105	COG3300	MHYT domain
GO175_RS11110	COG0295	cytidine deaminase activity
GO175_RS11115	COG1346	cytolysis
GO175_RS11125	COG2925	Exonuclease
GO175_RS11140	COG0702	epimerase
GO175_RS11145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GO175_RS11150	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GO175_RS11155	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GO175_RS11170	COG2988	succinylglutamate desuccinylase activity
GO175_RS11175	COG4139	cobalamin transport
GO175_RS11180	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GO175_RS11230	COG0583	DNA-binding transcription factor activity
GO175_RS11240	COG1451	nucleotide metabolic process
GO175_RS11255	COG3063	Type IV pilus biogenesis stability protein PilW
GO175_RS11260	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GO175_RS11280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO175_RS11295	COG3290	protein histidine kinase activity
GO175_RS11300	COG4565	transcriptional regulatory protein
GO175_RS11310	COG0784	Response regulator, receiver
GO175_RS11310	COG0835	chemotaxis
GO175_RS11325	COG0745	RESPONSE REGULATOR receiver
GO175_RS11325	COG3706	GGDEF domain
GO175_RS11370	COG1278	Cold shock
GO175_RS11405	COG0668	transmembrane transport
GO175_RS11420	COG0745	RESPONSE REGULATOR receiver
GO175_RS11425	COG5002	protein histidine kinase activity
GO175_RS11430	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GO175_RS11450	COG2010	Cytochrome c
GO175_RS11470	COG3391	amine dehydrogenase activity
GO175_RS11475	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GO175_RS11480	COG1254	Belongs to the acylphosphatase family
GO175_RS11485	COG2920	part of a sulfur-relay system
GO175_RS11490	COG0670	Belongs to the BI1 family
GO175_RS11495	COG1126	abc transporter atp-binding protein
GO175_RS11500	COG0765	amino acid transport
GO175_RS11505	COG4597	amino acid ABC transporter
GO175_RS11510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO175_RS11520	COG0561	phosphatase activity
GO175_RS11525	COG0602	queuosine metabolic process
GO175_RS11535	COG3005	denitrification pathway
GO175_RS11540	COG0243	molybdopterin cofactor binding
GO175_RS11550	COG3706	GGDEF domain
GO175_RS11550	COG0745	RESPONSE REGULATOR receiver
GO175_RS11570	COG2999	glutathione oxidoreductase activity
GO175_RS11585	COG5001	Diguanylate cyclase
GO175_RS11585	COG3300	MHYT domain
GO175_RS11595	COG3706	GGDEF domain
GO175_RS11600	COG0443	Heat shock 70 kDa protein
GO175_RS11615	COG3706	GGDEF domain
GO175_RS11640	COG3005	denitrification pathway
GO175_RS11650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GO175_RS11655	COG1643	Atp-dependent helicase
GO175_RS11665	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GO175_RS11675	COG3501	Rhs element vgr protein
GO175_RS11700	COG1115	amino acid carrier protein
GO175_RS11725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO175_RS11730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GO175_RS11730	COG0574	Belongs to the PEP-utilizing enzyme family
GO175_RS11745	COG2996	Protein conserved in bacteria
GO175_RS11750	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GO175_RS11750	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GO175_RS11755	COG3008	intermembrane lipid transfer
GO175_RS11760	COG2995	paraquat-inducible protein a
GO175_RS11765	COG1132	(ABC) transporter
GO175_RS11770	COG1956	GAF domain-containing protein
GO175_RS11795	COG0308	aminopeptidase N
GO175_RS11810	COG0167	dihydroorotate dehydrogenase activity
GO175_RS11820	COG0116	Belongs to the methyltransferase superfamily
GO175_RS11820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GO175_RS11830	COG0488	(ABC) transporter
GO175_RS11845	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO175_RS11850	COG1067	ATP-dependent peptidase activity
GO175_RS11855	COG3120	sequence-specific DNA binding
GO175_RS11915	COG3278	Belongs to the heme-copper respiratory oxidase family
GO175_RS11930	COG2010	Cytochrome c
GO175_RS11940	COG2217	Heavy metal translocating P-type atpase
GO175_RS11955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GO175_RS11960	COG0589	response to stress
GO175_RS11985	COG3842	ATPase activity
GO175_RS11990	COG1176	ABC-type spermidine putrescine transport system, permease component I
GO175_RS11995	COG1177	transmembrane transport
GO175_RS12000	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GO175_RS12005	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GO175_RS12010	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GO175_RS12015	COG0004	ammonium transporteR
GO175_RS12030	COG0437	4 iron, 4 sulfur cluster binding
GO175_RS12045	COG3381	protein complex oligomerization
GO175_RS12065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GO175_RS12080	COG3852	Histidine kinase
GO175_RS12085	COG2204	response regulator
GO175_RS12095	COG4662	Binding-protein-dependent transport system inner membrane component
GO175_RS12100	COG3842	ATPase activity
GO175_RS12105	COG0746	molybdenum cofactor guanylyltransferase activity
GO175_RS12110	COG0303	'Molybdopterin
GO175_RS12120	COG1940	carbohydrate kinase activity
GO175_RS12135	COG0840	transmembrane signaling receptor activity
GO175_RS12140	COG0791	NLP P60 protein
GO175_RS12160	COG0307	riboflavin synthase, alpha
GO175_RS12175	COG1793	dna ligase
GO175_RS12180	COG4667	esterase of the alpha-beta hydrolase superfamily
GO175_RS12200	COG0848	biopolymer transport protein
GO175_RS12205	COG0811	peptide transport
GO175_RS12210	COG0811	peptide transport
GO175_RS12220	COG3040	lipid binding
GO175_RS12245	COG0395	ABC-type sugar transport system, permease component
GO175_RS12250	COG3842	ATPase activity
GO175_RS12255	COG1349	DNA-binding transcription factor activity
GO175_RS12260	COG0584	glycerophosphoryl diester phosphodiesterase
GO175_RS12265	COG2731	YhcH YjgK YiaL family protein
GO175_RS12285	COG0625	glutathione transferase activity
GO175_RS12295	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GO175_RS12305	COG2200	EAL domain
GO175_RS12310	COG2195	Cleaves the N-terminal amino acid of tripeptides
GO175_RS12325	COG2814	Major facilitator Superfamily
GO175_RS12330	COG1566	PFAM secretion protein HlyD family protein
GO175_RS12345	COG2828	Protein conserved in bacteria
GO175_RS12350	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GO175_RS12355	COG0372	Belongs to the citrate synthase family
GO175_RS12360	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GO175_RS12370	COG2169	Transcriptional regulator
GO175_RS12370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GO175_RS12405	COG1129	ABC transporter
GO175_RS12415	COG3250	beta-galactosidase activity
GO175_RS12425	COG2991	Protein conserved in bacteria
GO175_RS12430	COG0778	Nitroreductase
GO175_RS12435	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GO175_RS12440	COG0583	DNA-binding transcription factor activity
GO175_RS12450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO175_RS12450	COG4191	Histidine kinase
GO175_RS12455	COG0471	metal ion transport
GO175_RS12475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO175_RS12480	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GO175_RS12485	COG3768	UPF0283 membrane protein
GO175_RS12490	COG3106	COG3106 Predicted ATPase
GO175_RS12505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GO175_RS12520	COG0494	nUDIX hydrolase
GO175_RS12525	COG0814	amino acid
GO175_RS12530	COG1760	l-serine dehydratase
GO175_RS12535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO175_RS12540	COG0577	efflux transmembrane transporter activity
GO175_RS12540	COG1136	(ABC) transporter
GO175_RS12545	COG1538	Outer membrane efflux protein
GO175_RS12550	COG0720	synthase
GO175_RS12555	COG0840	transmembrane signaling receptor activity
GO175_RS12560	COG0017	Asparaginyl-tRNA synthetase
GO175_RS12575	COG1448	Aminotransferase
GO175_RS12585	COG0517	IMP dehydrogenase activity
GO175_RS12590	COG2176	DNA-directed DNA polymerase activity
GO175_RS12595	COG0840	transmembrane signaling receptor activity
GO175_RS12600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GO175_RS12605	COG1846	Transcriptional regulator
GO175_RS12610	COG2197	response regulator
GO175_RS12625	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GO175_RS12640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GO175_RS12645	COG3108	Peptidase M15
GO175_RS12650	COG2989	Protein conserved in bacteria
GO175_RS12675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GO175_RS12690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GO175_RS12695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GO175_RS12725	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GO175_RS12730	COG3265	gluconokinase activity
GO175_RS12735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GO175_RS12745	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GO175_RS12795	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GO175_RS12810	COG4181	ATPase activity
GO175_RS12815	COG0534	Mate efflux family protein
GO175_RS12820	COG0702	epimerase
GO175_RS12830	COG2814	Major facilitator Superfamily
GO175_RS12840	COG1061	Type III restriction enzyme res subunit
GO175_RS12850	COG0745	RESPONSE REGULATOR receiver
GO175_RS12855	COG2205	protein histidine kinase activity
GO175_RS12860	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GO175_RS12875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GO175_RS12880	COG0583	DNA-binding transcription factor activity
GO175_RS12895	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GO175_RS12900	COG1982	Orn Lys Arg decarboxylase major
GO175_RS12905	COG1982	Orn Lys Arg decarboxylase major
GO175_RS12910	COG0531	amino acid
GO175_RS12925	COG0531	amino acid
GO175_RS12950	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GO175_RS12950	COG3264	Mechanosensitive ion channel
GO175_RS12965	COG1127	ABC transporter
GO175_RS12970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GO175_RS12975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GO175_RS12985	COG1278	Cold shock
GO175_RS12995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GO175_RS13000	COG3706	GGDEF domain
GO175_RS13015	COG0814	amino acid
GO175_RS13025	COG1131	(ABC) transporter
GO175_RS13030	COG0842	Transport permease protein
GO175_RS13040	COG3313	Fe-S protein
GO175_RS13050	COG4134	Bacterial extracellular solute-binding protein
GO175_RS13055	COG4135	transport system, permease component
GO175_RS13060	COG4136	ATPase activity
GO175_RS13065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GO175_RS13070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GO175_RS13080	COG0564	pseudouridine synthase activity
GO175_RS13090	COG0733	neurotransmitter:sodium symporter activity
GO175_RS13100	COG0626	cystathionine gamma-synthase activity
GO175_RS13130	COG0519	Catalyzes the synthesis of GMP from XMP
GO175_RS13145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO175_RS13160	COG1842	Phage shock protein A
GO175_RS13165	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GO175_RS13175	COG4168	peptide transport system, permease
GO175_RS13180	COG4171	peptide transport system, permease
GO175_RS13190	COG4172	Belongs to the ABC transporter superfamily
GO175_RS13205	COG1227	inorganic diphosphatase activity
GO175_RS13225	COG0243	molybdopterin cofactor binding
GO175_RS13230	COG3005	denitrification pathway
GO175_RS13235	COG4459	periplasmic nitrate reductase
GO175_RS13240	COG0390	transport system, permease component
GO175_RS13245	COG2116	formate transmembrane transporter activity
GO175_RS13265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GO175_RS13270	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GO175_RS13275	COG1435	thymidine kinase activity
GO175_RS13290	COG4106	trans-aconitate 2-methyltransferase activity
GO175_RS13295	COG0500	methyltransferase
GO175_RS13300	COG4067	protein conserved in archaea
GO175_RS13300	COG0189	ligase activity
GO175_RS13310	COG0189	ligase activity
GO175_RS13315	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GO175_RS13320	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GO175_RS13325	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GO175_RS13330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GO175_RS13335	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GO175_RS13340	COG0745	RESPONSE REGULATOR receiver
GO175_RS13345	COG3381	protein complex oligomerization
GO175_RS13350	COG1609	Transcriptional regulator
GO175_RS13355	COG3070	regulator of competence-specific genes
GO175_RS13375	COG0297	glycogen (starch) synthase activity
GO175_RS13380	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GO175_RS13385	COG3706	GGDEF domain
GO175_RS13385	COG0745	RESPONSE REGULATOR receiver
GO175_RS13390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GO175_RS13400	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GO175_RS13410	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GO175_RS13415	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GO175_RS13420	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GO175_RS13425	COG0542	response to heat
GO175_RS13430	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GO175_RS13435	COG1278	Cold shock
GO175_RS13445	COG1187	pseudouridine synthase activity
GO175_RS13450	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GO175_RS13450	COG0140	phosphoribosyl-ATP diphosphatase activity
GO175_RS13460	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GO175_RS13465	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GO175_RS13470	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GO175_RS13470	COG0131	Imidazoleglycerol-phosphate dehydratase
GO175_RS13475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GO175_RS13480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GO175_RS13485	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GO175_RS13495	COG1757	Na H antiporter
GO175_RS13500	COG2916	Histone family protein nucleoid-structuring protein H-NS
GO175_RS13505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO175_RS13510	COG0482	sulfurtransferase activity
GO175_RS13515	COG2915	High frequency lysogenization protein hflD homolog
GO175_RS13520	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GO175_RS13540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GO175_RS13555	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS13565	COG0501	Belongs to the peptidase M48B family
GO175_RS13570	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GO175_RS13575	COG2226	methyltransferase
GO175_RS13585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GO175_RS13590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GO175_RS13600	COG2146	nitrite reductase [NAD(P)H] activity
GO175_RS13600	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GO175_RS13605	COG1116	anion transmembrane transporter activity
GO175_RS13610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GO175_RS13615	COG1116	anion transmembrane transporter activity
GO175_RS13615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GO175_RS13630	COG1648	precorrin-2 dehydrogenase activity
GO175_RS13630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GO175_RS13635	COG0243	molybdopterin cofactor binding
GO175_RS13645	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GO175_RS13650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GO175_RS13655	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GO175_RS13660	COG0653	protein targeting
GO175_RS13675	COG3706	GGDEF domain
GO175_RS13685	COG4120	Belongs to the binding-protein-dependent transport system permease family
GO175_RS13695	COG3092	negative regulation of chromosome organization
GO175_RS13700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GO175_RS13705	COG0857	belongs to the CobB CobQ family
GO175_RS13705	COG0280	phosphate acetyltransferase
GO175_RS13710	COG3174	membrane
GO175_RS13715	COG0435	Glutathione S-transferase
GO175_RS13730	COG0444	Belongs to the ABC transporter superfamily
GO175_RS13735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO175_RS13740	COG0601	transmembrane transport
GO175_RS13770	COG0204	Acyl-transferase
GO175_RS13770	COG0318	PFAM AMP-dependent synthetase and ligase
GO175_RS13775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GO175_RS13780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GO175_RS13790	COG0318	PFAM AMP-dependent synthetase and ligase
GO175_RS13800	COG1216	Glycosyl transferase, family 2
GO175_RS13805	COG2986	histidine ammonia-lyase
GO175_RS13840	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS13855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO175_RS13865	COG2199	diguanylate cyclase activity
GO175_RS13865	COG2202	Pas domain
GO175_RS13865	COG2200	EAL domain
GO175_RS13870	COG1621	beta-fructofuranosidase activity
GO175_RS13880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO175_RS13880	COG1263	PTS System
GO175_RS13890	COG0745	RESPONSE REGULATOR receiver
GO175_RS13900	COG3708	Transcriptional regulator
GO175_RS13900	COG2207	Transcriptional regulator
GO175_RS13905	COG2814	Major facilitator Superfamily
GO175_RS13910	COG1566	PFAM secretion protein HlyD family protein
GO175_RS13915	COG1538	Outer membrane efflux protein
GO175_RS13925	COG0747	negative chemotaxis
GO175_RS13930	COG0601	transmembrane transport
GO175_RS13935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO175_RS13940	COG4172	Belongs to the ABC transporter superfamily
GO175_RS13945	COG0351	phosphomethylpyrimidine kinase
GO175_RS13955	COG0352	thiamine-phosphate diphosphorylase activity
GO175_RS13960	COG1741	Belongs to the pirin family
GO175_RS13965	COG2723	6-phospho-beta-galactosidase activity
GO175_RS13970	COG1609	Transcriptional regulator
GO175_RS13980	COG1120	ATPase activity
GO175_RS13985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GO175_RS13995	COG1629	transport
GO175_RS13995	COG4774	siderophore transport
GO175_RS14000	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO175_RS14005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO175_RS14010	COG4592	Periplasmic binding protein
GO175_RS14025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GO175_RS14025	COG3433	isochorismatase activity
GO175_RS14025	COG2226	methyltransferase
GO175_RS14030	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO175_RS14035	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS14040	COG1169	isochorismate synthase
GO175_RS14045	COG1021	2,3-dihydroxybenzoate-AMP ligase
GO175_RS14055	COG2814	Major facilitator Superfamily
GO175_RS14060	COG2249	NAD(P)H dehydrogenase (quinone) activity
GO175_RS14100	COG1294	oxidase, subunit
GO175_RS14105	COG1271	oxidase subunit
GO175_RS14110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO175_RS14125	COG3258	Cytochrome c
GO175_RS14130	COG2863	cytochrome
GO175_RS14155	COG4566	intracellular signal transduction
GO175_RS14175	COG2194	sulfuric ester hydrolase activity
GO175_RS14180	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GO175_RS14185	COG1368	sulfuric ester hydrolase activity
GO175_RS14190	COG0513	Belongs to the DEAD box helicase family
GO175_RS14200	COG0671	phosphoesterase, PA-phosphatase related
GO175_RS14205	COG0745	RESPONSE REGULATOR receiver
GO175_RS14210	COG0642	Histidine kinase
GO175_RS14225	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO175_RS14230	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO175_RS14260	COG2207	Transcriptional regulator
GO175_RS14265	COG1881	PFAM PEBP family protein
GO175_RS14270	COG1013	pyruvate-flavodoxin oxidoreductase activity
GO175_RS14275	COG0674	pyruvate-flavodoxin oxidoreductase activity
GO175_RS14275	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GO175_RS14280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO175_RS14285	COG2207	Transcriptional regulator
GO175_RS14310	COG1278	Cold shock
GO175_RS14320	COG0697	spore germination
GO175_RS14325	COG0431	NADPH-dependent FMN reductase
GO175_RS14355	COG1073	alpha beta
GO175_RS14360	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS14365	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS14370	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS14380	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS14385	COG4221	oxidoreductase activity
GO175_RS14405	COG1309	transcriptional regulator
GO175_RS14480	COG2199	diguanylate cyclase activity
GO175_RS14480	COG2203	Gaf domain
GO175_RS14495	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GO175_RS14500	COG1946	Acyl-CoA thioesterase
GO175_RS14510	COG1522	sequence-specific DNA binding
GO175_RS14535	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GO175_RS14550	COG2204	response regulator
GO175_RS14555	COG2885	chlorophyll binding
GO175_RS14575	COG1987	bacterial-type flagellum assembly
GO175_RS14585	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GO175_RS14600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GO175_RS14605	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GO175_RS14625	COG1580	Controls the rotational direction of flagella during chemotaxis
GO175_RS14630	COG1191	sigma factor activity
GO175_RS14635	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GO175_RS14640	COG1360	Flagellar Motor Protein
GO175_RS14650	COG3015	lipoprotein NlpE involved in copper resistance
GO175_RS14655	COG0702	epimerase
GO175_RS14705	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GO175_RS14740	COG4786	Flagellar basal body rod
GO175_RS14740	COG1256	bacterial-type flagellum assembly
GO175_RS14750	COG1706	bacterial-type flagellum-dependent cell motility
GO175_RS14755	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GO175_RS14760	COG4786	Flagellar basal body rod
GO175_RS14770	COG1749	Flagellar hook protein flgE
GO175_RS14775	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GO175_RS14780	COG1558	bacterial-type flagellum-dependent cell motility
GO175_RS14785	COG1815	bacterial-type flagellum-dependent cell motility
GO175_RS14805	COG0741	lytic transglycosylase activity
GO175_RS14805	COG1388	LysM domain
GO175_RS14810	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GO175_RS14830	COG0477	Major facilitator Superfamily
GO175_RS14835	COG2855	membrane
GO175_RS14850	COG1441	menaquinone biosynthetic process
GO175_RS14855	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GO175_RS14860	COG0596	Alpha beta hydrolase
GO175_RS14865	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GO175_RS14870	COG1169	isochorismate synthase
GO175_RS14875	COG0436	Aminotransferase
GO175_RS14880	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GO175_RS14885	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GO175_RS14905	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GO175_RS14905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GO175_RS14920	COG0616	signal peptide processing
GO175_RS14925	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS14940	COG0587	DNA-directed DNA polymerase activity
GO175_RS14945	COG0835	chemotaxis
GO175_RS14945	COG0784	Response regulator, receiver
GO175_RS14950	COG1940	carbohydrate kinase activity
GO175_RS14955	COG0469	pyruvate kinase activity
GO175_RS14960	COG4667	esterase of the alpha-beta hydrolase superfamily
GO175_RS14975	COG0733	neurotransmitter:sodium symporter activity
GO175_RS14990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO175_RS14990	COG1263	PTS System
GO175_RS15000	COG1263	PTS System
GO175_RS15000	COG2190	(PTS) system
GO175_RS15000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO175_RS15005	COG0084	hydrolase, TatD family'
GO175_RS15010	COG0470	DNA polymerase III
GO175_RS15015	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GO175_RS15020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GO175_RS15025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GO175_RS15030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GO175_RS15050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GO175_RS15055	COG0416	fatty acid biosynthetic process
GO175_RS15065	COG1399	metal-binding, possibly nucleic acid-binding protein
GO175_RS15070	COG0424	maF-like protein
GO175_RS15075	COG0564	pseudouridine synthase activity
GO175_RS15080	COG1530	ribonuclease E activity
GO175_RS15090	COG0659	secondary active sulfate transmembrane transporter activity
GO175_RS15100	COG1454	alcohol dehydrogenase
GO175_RS15100	COG1012	belongs to the aldehyde dehydrogenase family
GO175_RS15105	COG2095	MarC family integral membrane protein
GO175_RS15110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GO175_RS15115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GO175_RS15120	COG1757	Na H antiporter
GO175_RS15130	COG3081	Nucleoid-associated protein
GO175_RS15140	COG3083	sulfuric ester hydrolase activity
GO175_RS15160	COG1448	Aminotransferase
GO175_RS15170	COG0123	including yeast histone deacetylase and acetoin utilization protein
GO175_RS15185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GO175_RS15225	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GO175_RS15230	COG2159	amidohydrolase
GO175_RS15235	COG0583	DNA-binding transcription factor activity
GO175_RS15250	COG0667	Aldo Keto reductase
GO175_RS15275	COG3384	dioxygenase
GO175_RS15280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GO175_RS15285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GO175_RS15305	COG2853	Lipoprotein
GO175_RS15320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GO175_RS15325	COG1138	Cytochrome C-type biogenesis protein
GO175_RS15330	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GO175_RS15335	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GO175_RS15340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GO175_RS15345	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GO175_RS15350	COG4133	protoheme IX ABC transporter activity
GO175_RS15360	COG0835	chemotaxis
GO175_RS15370	COG1192	Involved in chromosome partitioning
GO175_RS15375	COG2201	protein-glutamate methylesterase activity
GO175_RS15380	COG2198	Histidine kinase
GO175_RS15380	COG0643	Histidine kinase
GO175_RS15385	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GO175_RS15400	COG0455	bacterial-type flagellum organization
GO175_RS15415	COG2062	phosphohistidine phosphatase, SixA
GO175_RS15425	COG3102	Protein conserved in bacteria
GO175_RS15430	COG0018	arginyl-trna synthetase
GO175_RS15450	COG1918	ferrous iron import across plasma membrane
GO175_RS15460	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GO175_RS15465	COG1121	(ABC) transporter
GO175_RS15470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GO175_RS15485	COG0508	dehydrogenase complex catalyzes the overall conversion of
GO175_RS15490	COG0567	Dehydrogenase, E1 component
GO175_RS15505	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GO175_RS15510	COG2009	succinate dehydrogenase
GO175_RS15520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GO175_RS15530	COG0033	Phosphoglucomutase
GO175_RS15535	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GO175_RS15540	COG0596	Alpha beta hydrolase
GO175_RS15555	COG1346	cytolysis
GO175_RS15560	COG1380	Effector of murein hydrolase LrgA
GO175_RS15565	COG0583	DNA-binding transcription factor activity
GO175_RS15575	COG0735	belongs to the Fur family
GO175_RS15580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GO175_RS15585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GO175_RS15590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GO175_RS15610	COG3101	peptidyl-lysine hydroxylation
GO175_RS15615	COG2860	membrane
GO175_RS15620	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS15625	COG0583	DNA-binding transcription factor activity
GO175_RS15630	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GO175_RS15635	COG2890	protein-(glutamine-N5) methyltransferase activity
GO175_RS15655	COG1987	bacterial-type flagellum assembly
GO175_RS15695	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GO175_RS15700	COG0714	Associated with various cellular activities
GO175_RS15705	COG0556	nucleotide-excision repair
GO175_RS15725	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GO175_RS15735	COG2204	response regulator
GO175_RS15740	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GO175_RS15755	COG1482	cell wall glycoprotein biosynthetic process
GO175_RS15760	COG0840	transmembrane signaling receptor activity
GO175_RS15765	COG4580	involved in the transport of maltose and maltodextrins
GO175_RS15770	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GO175_RS15775	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GO175_RS15785	COG1609	Transcriptional regulator
GO175_RS15800	COG5578	integral membrane protein
GO175_RS15805	COG0395	ABC-type sugar transport system, permease component
GO175_RS15810	COG1175	transmembrane transport
GO175_RS15855	COG1061	Type III restriction enzyme res subunit
GO175_RS15885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GO175_RS15890	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GO175_RS15890	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GO175_RS15900	COG0745	RESPONSE REGULATOR receiver
GO175_RS15920	COG3036	rescue of stalled ribosome
GO175_RS15925	COG1278	Cold shock
GO175_RS15930	COG4681	YaeQ
GO175_RS15935	COG3706	GGDEF domain
GO175_RS15940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO175_RS15940	COG1017	nitric oxide dioxygenase activity
GO175_RS15945	COG3604	Transcriptional regulator
GO175_RS15955	COG2195	Cleaves the N-terminal amino acid of tripeptides
GO175_RS15960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GO175_RS15970	COG0366	Alpha amylase catalytic
GO175_RS15990	COG0714	Associated with various cellular activities
GO175_RS16010	COG2304	oxidoreductase activity
GO175_RS16025	COG3706	GGDEF domain
GO175_RS16035	COG5002	protein histidine kinase activity
GO175_RS16035	COG0784	Response regulator, receiver
GO175_RS16035	COG2205	protein histidine kinase activity
GO175_RS16040	COG3706	GGDEF domain
GO175_RS16040	COG0745	RESPONSE REGULATOR receiver
GO175_RS16050	COG3724	N-succinylarginine dihydrolase activity
GO175_RS16055	COG1012	belongs to the aldehyde dehydrogenase family
GO175_RS16080	COG4948	Mandelate Racemase Muconate Lactonizing
GO175_RS16105	COG0583	DNA-binding transcription factor activity
GO175_RS16130	COG3171	Protein conserved in bacteria
GO175_RS16135	COG0589	response to stress
GO175_RS16145	COG3530	Putative quorum-sensing-regulated virulence factor
GO175_RS16155	COG0579	oxidoreductase
GO175_RS16170	COG2204	response regulator
GO175_RS16180	COG1929	Belongs to the glycerate kinase type-1 family
GO175_RS16185	COG0383	alpha-mannosidase activity
GO175_RS16190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO175_RS16190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO175_RS16190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO175_RS16195	COG2188	Transcriptional regulator
GO175_RS16220	COG3300	MHYT domain
GO175_RS16220	COG5001	Diguanylate cyclase
GO175_RS16225	COG2271	Major facilitator Superfamily
GO175_RS16230	COG0584	glycerophosphoryl diester phosphodiesterase
GO175_RS16235	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GO175_RS16240	COG0583	DNA-binding transcription factor activity
GO175_RS16250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO175_RS16255	COG1879	ABC-type sugar transport system periplasmic component
GO175_RS16260	COG1172	Belongs to the binding-protein-dependent transport system permease family
GO175_RS16265	COG1129	ABC transporter
GO175_RS16270	COG1869	D-ribose catabolic process
GO175_RS16380	COG1280	lysine exporter protein (LysE YggA)
GO175_RS16385	COG1846	Transcriptional regulator
GO175_RS16400	COG0564	pseudouridine synthase activity
GO175_RS16405	COG1309	transcriptional regulator
GO175_RS16410	COG2130	NADP-dependent
GO175_RS16425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO175_RS16455	COG3842	ATPase activity
GO175_RS16465	COG2200	EAL domain
GO175_RS16470	COG0656	L-ascorbic acid biosynthetic process
GO175_RS16475	COG1902	pentaerythritol trinitrate reductase activity
GO175_RS16480	COG0583	DNA-binding transcription factor activity
GO175_RS16485	COG2814	Major facilitator Superfamily
GO175_RS16505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GO175_RS16520	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GO175_RS16530	COG4702	Belongs to the UPF0303 family
GO175_RS16535	COG0673	inositol 2-dehydrogenase activity
GO175_RS16540	COG1349	DNA-binding transcription factor activity
GO175_RS16545	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GO175_RS16565	COG3240	lipase activity
GO175_RS16570	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS16575	COG0583	DNA-binding transcription factor activity
GO175_RS16585	COG1120	ATPase activity
GO175_RS16590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO175_RS16595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO175_RS16600	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GO175_RS16605	COG4774	siderophore transport
GO175_RS16630	COG0840	transmembrane signaling receptor activity
GO175_RS16635	COG3384	dioxygenase
GO175_RS16640	COG0583	DNA-binding transcription factor activity
GO175_RS16650	COG1342	Belongs to the UPF0251 family
GO175_RS16655	COG0778	Nitroreductase
GO175_RS16660	COG0583	DNA-binding transcription factor activity
GO175_RS16670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO175_RS16675	COG0697	spore germination
GO175_RS16690	COG2814	Major facilitator Superfamily
GO175_RS16695	COG0583	DNA-binding transcription factor activity
GO175_RS16700	COG3300	MHYT domain
GO175_RS16700	COG5001	Diguanylate cyclase
GO175_RS16705	COG0739	heme binding
GO175_RS16720	COG0659	secondary active sulfate transmembrane transporter activity
GO175_RS16735	COG2199	diguanylate cyclase activity
GO175_RS16745	COG0581	inorganic phosphate transmembrane transporter activity
GO175_RS16750	COG0573	inorganic phosphate transmembrane transporter activity
GO175_RS16755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GO175_RS16760	COG0840	transmembrane signaling receptor activity
GO175_RS16765	COG0513	Belongs to the DEAD box helicase family
GO175_RS16775	COG1388	LysM domain
GO175_RS16775	COG1376	ErfK ybiS ycfS ynhG family protein
GO175_RS16780	COG0415	Belongs to the DNA photolyase family
GO175_RS16790	COG3272	Protein of unknown function (DUF1722)
GO175_RS16795	COG0813	purine-nucleoside phosphorylase activity
GO175_RS16810	COG3706	GGDEF domain
GO175_RS16820	COG1566	PFAM secretion protein HlyD family protein
GO175_RS16855	COG0786	glutamate:sodium symporter activity
GO175_RS16870	COG1999	signal sequence binding
GO175_RS16880	COG1162	GTPase activity
GO175_RS16885	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GO175_RS16900	COG4580	involved in the transport of maltose and maltodextrins
GO175_RS16920	COG1132	(ABC) transporter
GO175_RS16930	COG0671	phosphoesterase, PA-phosphatase related
GO175_RS16940	COG3383	formate dehydrogenase (NAD+) activity
GO175_RS16955	COG0840	transmembrane signaling receptor activity
GO175_RS16965	COG1131	(ABC) transporter
GO175_RS16970	COG2188	Transcriptional regulator
GO175_RS16980	COG3033	Beta-eliminating lyase
GO175_RS16985	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GO175_RS16990	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GO175_RS17000	COG0471	metal ion transport
GO175_RS17045	COG3501	Rhs element vgr protein
GO175_RS17055	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GO175_RS17060	COG1640	4-alpha-glucanotransferase
GO175_RS17065	COG0058	SHG alpha-glucan phosphorylase activity
GO175_RS17070	COG2909	trisaccharide binding
GO175_RS17085	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GO175_RS17090	COG1845	cytochrome c oxidase, subunit III
GO175_RS17095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GO175_RS17100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GO175_RS17115	COG2084	Dehydrogenase
GO175_RS17130	COG0217	transcriptional regulatory protein
GO175_RS17165	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GO175_RS17170	COG1444	tRNA N-acetyltransferase activity
GO175_RS17180	COG0745	RESPONSE REGULATOR receiver
GO175_RS17185	COG0643	Histidine kinase
GO175_RS17185	COG2198	Histidine kinase
GO175_RS17190	COG0835	chemotaxis
GO175_RS17195	COG0835	chemotaxis
GO175_RS17200	COG0840	transmembrane signaling receptor activity
GO175_RS17205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GO175_RS17215	COG2201	protein-glutamate methylesterase activity
GO175_RS17230	COG0745	RESPONSE REGULATOR receiver
GO175_RS17260	COG0259	pyridoxamine-phosphate oxidase activity
GO175_RS17270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GO175_RS17300	COG0840	transmembrane signaling receptor activity
GO175_RS17315	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GO175_RS17325	COG0513	Belongs to the DEAD box helicase family
GO175_RS17335	COG0583	DNA-binding transcription factor activity
GO175_RS17340	COG2226	methyltransferase
GO175_RS17355	COG0724	RNA recognition motif
GO175_RS17360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GO175_RS17365	COG1522	sequence-specific DNA binding
GO175_RS17370	COG2610	gluconate transmembrane transporter activity
GO175_RS17375	COG3622	Belongs to the hyi family
GO175_RS17380	COG0235	Class ii aldolase
GO175_RS17385	COG3395	kinase activity
GO175_RS17390	COG2084	Dehydrogenase
GO175_RS17395	COG1349	DNA-binding transcription factor activity
GO175_RS17410	COG0583	DNA-binding transcription factor activity
GO175_RS17415	COG2910	NAD(P)H-binding
GO175_RS17430	COG1335	isochorismatase
GO175_RS17435	COG2207	Transcriptional regulator
GO175_RS17435	COG1609	Transcriptional regulator
GO175_RS17450	COG2329	Antibiotic biosynthesis monooxygenase
GO175_RS17455	COG3304	Inner membrane component domain
GO175_RS17465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO175_RS17490	COG0583	DNA-binding transcription factor activity
GO175_RS17495	COG4221	oxidoreductase activity
GO175_RS17510	COG3730	PTS system glucitol sorbitol-specific
GO175_RS17515	COG1349	DNA-binding transcription factor activity
GO175_RS17525	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS17530	COG3731	PTS system glucitol sorbitol-specific IIA component
GO175_RS17540	COG3730	PTS system glucitol sorbitol-specific
GO175_RS17550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GO175_RS17560	COG1403	HNH endonuclease
GO175_RS17570	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GO175_RS17590	COG2176	DNA-directed DNA polymerase activity
GO175_RS17610	COG0443	Heat shock 70 kDa protein
GO175_RS17615	COG0095	Lipoate-protein ligase
GO175_RS17630	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GO175_RS17635	COG1473	amidohydrolase
GO175_RS17650	COG3722	fumarate hydratase activity
GO175_RS17660	COG2213	PTS system mannitol-specific
GO175_RS17660	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO175_RS17665	COG0739	heme binding
GO175_RS17680	COG0363	glucosamine-6-phosphate deaminase activity
GO175_RS17705	COG0402	S-adenosylhomocysteine deaminase activity
GO175_RS17710	COG2259	Doxx family
GO175_RS17715	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GO175_RS17720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GO175_RS17730	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GO175_RS17735	COG1301	dicarboxylic acid transport
GO175_RS17755	COG1917	Cupin 2, conserved barrel domain protein
GO175_RS17755	COG2169	Transcriptional regulator
GO175_RS17775	COG1566	PFAM secretion protein HlyD family protein
GO175_RS17790	COG1764	response to oxidative stress
GO175_RS17795	COG1846	Transcriptional regulator
GO175_RS17800	COG0179	Fumarylacetoacetate (FAA) hydrolase
GO175_RS17820	COG1280	lysine exporter protein (LysE YggA)
GO175_RS17830	COG1902	pentaerythritol trinitrate reductase activity
GO175_RS17835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GO175_RS17845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GO175_RS17875	COG1612	heme a metabolic process
GO175_RS17880	COG0109	protoheme IX farnesyltransferase activity
GO175_RS17895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO175_RS17905	COG5002	protein histidine kinase activity
GO175_RS17905	COG3447	MASE1 domain protein
GO175_RS17905	COG5001	Diguanylate cyclase
GO175_RS17925	COG2169	Transcriptional regulator
GO175_RS17945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO175_RS17950	COG0697	spore germination
GO175_RS17955	COG0477	Major facilitator Superfamily
GO175_RS17960	COG0625	glutathione transferase activity
GO175_RS17970	COG1942	4-Oxalocrotonate Tautomerase
GO175_RS17985	COG0583	DNA-binding transcription factor activity
GO175_RS18005	COG3152	Membrane
GO175_RS18015	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GO175_RS18025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GO175_RS18050	COG1304	FMN binding
GO175_RS18055	COG1620	l-lactate permease
GO175_RS18060	COG0583	DNA-binding transcription factor activity
GO175_RS18065	COG4172	Belongs to the ABC transporter superfamily
GO175_RS18075	COG1067	ATP-dependent peptidase activity
GO175_RS18085	COG2211	Major facilitator Superfamily
GO175_RS18090	COG0668	transmembrane transport
GO175_RS18095	COG0569	domain protein
GO175_RS18100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GO175_RS18110	COG3123	guanosine phosphorylase activity
GO175_RS18120	COG2814	Major facilitator Superfamily
GO175_RS18130	COG3501	Rhs element vgr protein
GO175_RS18230	COG2205	protein histidine kinase activity
GO175_RS18235	COG0745	RESPONSE REGULATOR receiver
GO175_RS18240	COG1741	Belongs to the pirin family
GO175_RS18250	COG5001	Diguanylate cyclase
GO175_RS18275	COG3706	GGDEF domain
GO175_RS18295	COG3706	GGDEF domain
GO175_RS18305	COG1846	Transcriptional regulator
GO175_RS18310	COG2315	Protein conserved in bacteria
GO175_RS18315	COG0784	Response regulator, receiver
GO175_RS18315	COG0835	chemotaxis
GO175_RS18320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GO175_RS18325	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GO175_RS18380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GO175_RS18400	COG1522	sequence-specific DNA binding
GO175_RS18410	COG0393	Putative heavy-metal-binding
GO175_RS18415	COG0823	Involved in the tonB-independent uptake of proteins
GO175_RS18420	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GO175_RS18425	COG0534	Mate efflux family protein
GO175_RS18435	COG1653	transport
GO175_RS18440	COG3842	ATPase activity
GO175_RS18445	COG0395	ABC-type sugar transport system, permease component
GO175_RS18450	COG1175	transmembrane transport
GO175_RS18470	COG0800	Aldolase
GO175_RS18475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO175_RS18490	COG1917	Cupin 2, conserved barrel domain protein
GO175_RS18500	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS18505	COG1414	Transcriptional regulator
GO175_RS18510	COG0517	IMP dehydrogenase activity
GO175_RS18530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO175_RS18540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO175_RS18580	COG3842	ATPase activity
GO175_RS18620	COG1349	DNA-binding transcription factor activity
GO175_RS18640	COG2354	Protein conserved in bacteria
GO175_RS18645	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GO175_RS18650	COG0418	dihydroorotase activity
GO175_RS18655	COG3217	Mosc domain protein beta barrel domain protein
GO175_RS18655	COG0633	Ferredoxin
GO175_RS18685	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GO175_RS18690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO175_RS18700	COG0848	biopolymer transport protein
GO175_RS18705	COG0811	peptide transport
GO175_RS18710	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GO175_RS18715	COG3721	Heme iron utilization protein
GO175_RS18720	COG0748	coenzyme F420 binding
GO175_RS18730	COG0531	amino acid
GO175_RS18735	COG1522	sequence-specific DNA binding
GO175_RS18765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO175_RS18770	COG2200	EAL domain
GO175_RS18795	COG0784	Response regulator, receiver
GO175_RS18795	COG5002	protein histidine kinase activity
GO175_RS18795	COG2205	protein histidine kinase activity
GO175_RS18800	COG3300	MHYT domain
GO175_RS18800	COG5001	Diguanylate cyclase
GO175_RS18815	COG1765	OsmC-like protein
GO175_RS18825	COG2171	N-acyltransferase activity
GO175_RS18850	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GO175_RS18880	COG0745	RESPONSE REGULATOR receiver
GO175_RS18895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GO175_RS18900	COG3186	Phenylalanine-4-hydroxylase
GO175_RS18905	COG2154	pterin-4-alpha-carbinolamine dehydratase
GO175_RS18910	COG0534	Mate efflux family protein
GO175_RS18920	COG0861	Integral membrane protein TerC family
GO175_RS18930	COG0456	acetyltransferase
GO175_RS18935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GO175_RS18940	COG0662	Cupin 2, conserved barrel domain protein
GO175_RS18945	COG0527	aspartate kinase activity
GO175_RS18950	COG0561	phosphatase activity
GO175_RS18960	COG0583	DNA-binding transcription factor activity
GO175_RS18970	COG3437	response regulator, receiver
GO175_RS18970	COG0784	Response regulator, receiver
GO175_RS18980	COG0113	porphobilinogen synthase activity
GO175_RS18985	COG0459	protein refolding
GO175_RS18990	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GO175_RS18995	COG2239	Acts as a magnesium transporter
GO175_RS19015	COG2113	Glycine betaine
GO175_RS19020	COG4176	ABC-type proline glycine betaine transport system permease component
GO175_RS19025	COG4175	Glycine betaine
GO175_RS19035	COG1166	arginine decarboxylase activity
GO175_RS19045	COG1522	sequence-specific DNA binding
GO175_RS19060	COG0765	amino acid transport
GO175_RS19070	COG1686	Belongs to the peptidase S11 family
GO175_RS19085	COG1566	PFAM secretion protein HlyD family protein
GO175_RS19095	COG3338	carbonate dehydratase activity
GO175_RS19130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GO175_RS19140	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GO175_RS19150	COG1280	lysine exporter protein (LysE YggA)
GO175_RS19155	COG0513	Belongs to the DEAD box helicase family
GO175_RS19170	COG0840	transmembrane signaling receptor activity
GO175_RS19185	COG2985	domain, Protein
GO175_RS19195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GO175_RS19215	COG1280	lysine exporter protein (LysE YggA)
GO175_RS19260	COG3122	Protein conserved in bacteria
GO175_RS19280	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GO175_RS19280	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GO175_RS19285	COG0509	glycine decarboxylation via glycine cleavage system
GO175_RS19300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GO175_RS19310	COG3706	GGDEF domain
GO175_RS19315	COG5001	Diguanylate cyclase
GO175_RS19320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO175_RS19335	COG0546	phosphoglycolate phosphatase activity
GO175_RS19355	COG0484	heat shock protein binding
GO175_RS19365	COG1716	ATPase activity
GO175_RS19365	COG5001	Diguanylate cyclase
GO175_RS19370	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GO175_RS19380	COG4181	ATPase activity
GO175_RS19385	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GO175_RS19395	COG1984	allophanate hydrolase subunit 2
GO175_RS19405	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GO175_RS19410	COG3447	MASE1 domain protein
GO175_RS19410	COG5002	protein histidine kinase activity
GO175_RS19410	COG5001	Diguanylate cyclase
GO175_RS19415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GO175_RS19420	COG0840	transmembrane signaling receptor activity
GO175_RS19425	COG0814	amino acid
GO175_RS19430	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GO175_RS19435	COG0513	Belongs to the DEAD box helicase family
GO175_RS19440	COG1309	transcriptional regulator
GO175_RS19450	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GO175_RS19465	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GO175_RS19505	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GO175_RS19515	COG0463	Glycosyl transferase, family 2
GO175_RS19525	COG0583	DNA-binding transcription factor activity
GO175_RS19530	COG0697	spore germination
GO175_RS19535	COG1917	Cupin 2, conserved barrel domain protein
GO175_RS19535	COG2207	Transcriptional regulator
GO175_RS19560	COG0330	HflC and HflK could
GO175_RS19570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GO175_RS19585	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GO175_RS19590	COG0583	DNA-binding transcription factor activity
GO175_RS19595	COG3781	membrane
GO175_RS19600	COG0243	molybdopterin cofactor binding
GO175_RS19605	COG1271	oxidase subunit
GO175_RS19610	COG1294	oxidase, subunit
GO175_RS19615	COG0800	Aldolase
GO175_RS19620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO175_RS19625	COG1904	glucuronate isomerase
GO175_RS19630	COG0246	Mannitol dehydrogenase
GO175_RS19645	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GO175_RS19655	COG2186	Transcriptional regulator
GO175_RS19670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO175_RS19685	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GO175_RS19695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GO175_RS19705	COG1120	ATPase activity
GO175_RS19710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GO175_RS19745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GO175_RS19775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GO175_RS19780	COG2146	nitrite reductase [NAD(P)H] activity
GO175_RS19785	COG2116	formate transmembrane transporter activity
GO175_RS19815	COG2814	Major facilitator Superfamily
GO175_RS19820	COG3118	belongs to the thioredoxin family
GO175_RS19825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GO175_RS19840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GO175_RS19850	COG1596	polysaccharide export
GO175_RS19875	COG0438	transferase activity, transferring glycosyl groups
GO175_RS19880	COG0297	glycogen (starch) synthase activity
GO175_RS19880	COG0438	transferase activity, transferring glycosyl groups
GO175_RS19895	COG0247	lactate metabolic process
GO175_RS19900	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GO175_RS19905	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GO175_RS19910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GO175_RS19915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GO175_RS19950	COG2827	Endonuclease containing a URI domain
GO175_RS19960	COG1879	ABC-type sugar transport system periplasmic component
GO175_RS19965	COG0784	Response regulator, receiver
GO175_RS19965	COG5002	protein histidine kinase activity
GO175_RS19985	COG1492	cobalamin metabolic process
GO175_RS19990	COG0725	ABC transporter, periplasmic molybdate-binding protein
GO175_RS19995	COG4149	molybdate abc transporter
GO175_RS20000	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GO175_RS20015	COG1289	transmembrane transporter activity
GO175_RS20115	COG0210	DNA helicase
GO175_RS20120	COG1335	isochorismatase
GO175_RS20125	COG1803	Methylglyoxal synthase
GO175_RS20130	COG1879	ABC-type sugar transport system periplasmic component
GO175_RS20135	COG2198	Histidine kinase
GO175_RS20135	COG0784	Response regulator, receiver
GO175_RS20135	COG2205	protein histidine kinase activity
GO175_RS20140	COG0469	pyruvate kinase activity
GO175_RS20145	COG2271	Major facilitator Superfamily
GO175_RS20150	COG1840	ABC-type Fe3 transport system, periplasmic component
GO175_RS20170	COG1979	alcohol dehydrogenase
GO175_RS20175	COG2207	Transcriptional regulator
GO175_RS20190	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GO175_RS20195	COG3706	GGDEF domain
GO175_RS20215	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GO175_RS20220	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GO175_RS20230	COG0183	Belongs to the thiolase family
GO175_RS20270	COG0243	molybdopterin cofactor binding
GO175_RS20285	COG3850	Histidine kinase
GO175_RS20290	COG2197	response regulator
GO175_RS20295	COG3069	C4-dicarboxylate transmembrane transporter activity
GO175_RS20310	COG2814	Major facilitator Superfamily
GO175_RS20315	COG0840	transmembrane signaling receptor activity
GO175_RS20320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO175_RS20325	COG0545	Peptidyl-prolyl cis-trans isomerase
GO175_RS20340	COG0840	transmembrane signaling receptor activity
GO175_RS20345	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GO175_RS20360	COG2897	thiosulfate sulfurtransferase activity
GO175_RS20365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GO175_RS20375	COG0302	gtp cyclohydrolase
GO175_RS20380	COG0531	amino acid
GO175_RS20390	COG4303	Ethanolamine ammonia lyase large subunit
GO175_RS20395	COG2207	Transcriptional regulator
GO175_RS20400	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GO175_RS20400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GO175_RS20405	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GO175_RS20410	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GO175_RS20420	COG1011	Hydrolase
GO175_RS20425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GO175_RS20435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO175_RS20445	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GO175_RS20455	COG3842	ATPase activity
GO175_RS20475	COG2866	Carboxypeptidase
GO175_RS20500	COG4166	transmembrane transport
GO175_RS20505	COG4174	ABC transporter (Permease)
GO175_RS20510	COG4239	(ABC) transporter, permease
GO175_RS20515	COG4172	Belongs to the ABC transporter superfamily
GO175_RS20520	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GO175_RS20535	COG0784	Response regulator, receiver
GO175_RS20535	COG2205	protein histidine kinase activity
GO175_RS20540	COG4251	negative regulation of phosphorylation
GO175_RS20540	COG5001	Diguanylate cyclase
GO175_RS20540	COG3706	GGDEF domain
GO175_RS20540	COG2203	Gaf domain
GO175_RS20550	COG2199	diguanylate cyclase activity
GO175_RS20560	COG2501	S4 domain
GO175_RS20600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO175_RS20625	COG1979	alcohol dehydrogenase
GO175_RS20630	COG2207	Transcriptional regulator
GO175_RS20650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GO175_RS20660	COG0488	(ABC) transporter
GO175_RS20700	COG3710	Transcriptional regulator
GO175_RS20730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO175_RS20745	COG2233	PERMEase
GO175_RS20765	COG1953	Uracil, thiamine, allantoin
GO175_RS20775	COG0765	amino acid transport
GO175_RS20780	COG0765	amino acid transport
GO175_RS20810	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GO175_RS20830	COG0402	S-adenosylhomocysteine deaminase activity
GO175_RS20835	COG2351	hydroxyisourate hydrolase activity
GO175_RS20875	COG1129	ABC transporter
GO175_RS20880	COG1309	transcriptional regulator
GO175_RS20890	COG3706	GGDEF domain
GO175_RS20900	COG0745	RESPONSE REGULATOR receiver
GO175_RS20900	COG3706	GGDEF domain
GO175_RS20915	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GO175_RS20920	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GO175_RS20930	COG0745	RESPONSE REGULATOR receiver
GO175_RS20950	COG0023	Translation Initiation Factor
GO175_RS20965	COG1181	Belongs to the D-alanine--D-alanine ligase family
GO175_RS20975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GO175_RS20975	COG1042	CoA-binding domain protein
GO175_RS20975	COG0045	succinate-CoA ligase (ADP-forming) activity
GO175_RS20980	COG0583	DNA-binding transcription factor activity
GO175_RS20985	COG4771	TonB-dependent receptor
GO175_RS20985	COG1629	transport
GO175_RS21005	COG2050	protein possibly involved in aromatic compounds catabolism
GO175_RS21010	COG0501	Belongs to the peptidase M48B family
GO175_RS21015	COG2824	Alkylphosphonate utilization operon protein PhnA
GO175_RS21025	COG0861	Integral membrane protein TerC family
GO175_RS21030	COG0737	Belongs to the 5'-nucleotidase family
GO175_RS21035	COG3593	DNA synthesis involved in DNA repair
GO175_RS21045	COG0583	DNA-binding transcription factor activity
GO175_RS21050	COG2116	formate transmembrane transporter activity
GO175_RS21055	COG2353	YceI-like domain
GO175_RS21060	COG3038	cytochrome b561
GO175_RS21085	COG5001	Diguanylate cyclase
GO175_RS21095	COG0243	molybdopterin cofactor binding
GO175_RS21100	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GO175_RS21105	COG0543	2 iron, 2 sulfur cluster binding
GO175_RS21105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO175_RS21110	COG2205	protein histidine kinase activity
GO175_RS21110	COG0784	Response regulator, receiver
GO175_RS21110	COG5002	protein histidine kinase activity
GO175_RS21115	COG3437	response regulator, receiver
GO175_RS21125	COG2207	Transcriptional regulator
GO175_RS21130	COG0582	viral genome integration into host DNA
GO175_RS21140	COG2916	Histone family protein nucleoid-structuring protein H-NS
GO175_RS21145	COG2202	Pas domain
GO175_RS21145	COG2200	EAL domain
GO175_RS21145	COG2199	diguanylate cyclase activity
GO175_RS21160	COG2203	Gaf domain
GO175_RS21160	COG4251	negative regulation of phosphorylation
GO175_RS21160	COG3706	GGDEF domain
GO175_RS21160	COG5001	Diguanylate cyclase
GO175_RS21195	COG2181	nitrate reductase activity
GO175_RS21200	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GO175_RS21210	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GO175_RS21215	COG2223	nitrite transmembrane transporter activity
GO175_RS21220	COG3850	Histidine kinase
GO175_RS21225	COG2197	response regulator
GO175_RS21230	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GO175_RS21240	COG3290	protein histidine kinase activity
GO175_RS21240	COG0840	transmembrane signaling receptor activity
GO175_RS21290	COG1518	maintenance of DNA repeat elements
GO175_RS21305	COG2003	Belongs to the UPF0758 family
GO175_RS21335	COG0328	RNA-DNA hybrid ribonuclease activity
GO175_RS21355	COG0523	cobalamin synthesis protein
GO175_RS21360	COG0038	chloride channel
GO175_RS21370	COG0156	8-amino-7-oxononanoate synthase activity
GO175_RS21375	COG0784	Response regulator, receiver
GO175_RS21375	COG2205	protein histidine kinase activity
GO175_RS21380	COG0419	ATPase involved in DNA repair
GO175_RS21390	COG1609	Transcriptional regulator
GO175_RS21395	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO175_RS21395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO175_RS21400	COG1105	Belongs to the carbohydrate kinase PfkB family
GO175_RS21405	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GO175_RS21405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO175_RS21405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO175_RS21410	COG0189	ligase activity
GO175_RS21410	COG4067	protein conserved in archaea
GO175_RS21420	COG0602	queuosine metabolic process
GO175_RS21425	COG1328	CTP reductase activity
GO175_RS21480	COG1280	lysine exporter protein (LysE YggA)
GO175_RS21485	COG0745	RESPONSE REGULATOR receiver
GO175_RS21495	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GO175_RS21505	COG0583	DNA-binding transcription factor activity
GO175_RS21520	COG1309	transcriptional regulator
GO175_RS21525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GO175_RS21555	COG1335	isochorismatase
GO175_RS21560	COG4977	sequence-specific DNA binding
GO175_RS21565	COG0456	acetyltransferase
GO175_RS21575	COG1280	lysine exporter protein (LysE YggA)
GO175_RS21580	COG0494	nUDIX hydrolase
GO175_RS21590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GO175_RS21620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO175_RS21640	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS21650	COG0454	-acetyltransferase
GO175_RS21710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GO175_RS21715	COG0789	Transcriptional regulator
GO175_RS21770	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS21780	COG4628	conserved protein (DUF2132)
GO175_RS21820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GO175_RS21825	COG0513	Belongs to the DEAD box helicase family
GO175_RS21830	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GO175_RS21840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GO175_RS21850	COG0583	DNA-binding transcription factor activity
GO175_RS21885	COG1349	DNA-binding transcription factor activity
GO175_RS21890	COG0110	maltose O-acetyltransferase activity
GO175_RS21895	COG3706	GGDEF domain
GO175_RS21905	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GO175_RS21910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GO175_RS21930	COG0747	negative chemotaxis
GO175_RS21935	COG4172	Belongs to the ABC transporter superfamily
GO175_RS21945	COG3437	response regulator, receiver
GO175_RS21950	COG0784	Response regulator, receiver
GO175_RS21950	COG2198	Histidine kinase
GO175_RS21950	COG2205	protein histidine kinase activity
GO175_RS21960	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GO175_RS21980	COG1595	DNA-templated transcription, initiation
GO175_RS21995	COG3217	Mosc domain protein beta barrel domain protein
GO175_RS21995	COG0633	Ferredoxin
GO175_RS22005	COG0583	DNA-binding transcription factor activity
GO175_RS22020	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GO175_RS22035	COG2423	ornithine cyclodeaminase activity
GO175_RS22045	COG4145	pantothenate transmembrane transporter activity
GO175_RS22050	COG0583	DNA-binding transcription factor activity
GO175_RS22055	COG0435	Glutathione S-transferase
GO175_RS22060	COG0400	carboxylic ester hydrolase activity
GO175_RS22065	COG1280	lysine exporter protein (LysE YggA)
GO175_RS22080	COG1473	amidohydrolase
GO175_RS22100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO175_RS22105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GO175_RS22110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GO175_RS22135	COG2721	sulfolactate sulfo-lyase activity
GO175_RS22205	COG2204	response regulator
GO175_RS22210	COG0438	transferase activity, transferring glycosyl groups
GO175_RS22245	COG0438	transferase activity, transferring glycosyl groups
GO175_RS22255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GO175_RS22260	COG0438	transferase activity, transferring glycosyl groups
GO175_RS22285	COG0625	glutathione transferase activity
GO175_RS22305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GO175_RS22315	COG0573	inorganic phosphate transmembrane transporter activity
GO175_RS22320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GO175_RS22340	COG1464	Belongs to the NlpA lipoprotein family
GO175_RS22345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GO175_RS22345	COG0512	Glutamine amidotransferase of anthranilate synthase
GO175_RS22365	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GO175_RS22380	COG0653	protein targeting
GO175_RS22385	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS22395	COG1028	Short-chain dehydrogenase reductase Sdr
GO175_RS22405	COG1024	Enoyl-CoA hydratase
GO175_RS22410	COG1024	Enoyl-CoA hydratase
GO175_RS22415	COG1960	acyl-CoA dehydrogenase activity
GO175_RS22425	COG0183	Belongs to the thiolase family
GO175_RS22435	COG1960	acyl-CoA dehydrogenase activity
GO175_RS22440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GO175_RS22445	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GO175_RS22460	COG0450	alkyl hydroperoxide reductase
GO175_RS22495	COG2207	Transcriptional regulator
GO175_RS22495	COG1609	Transcriptional regulator
GO175_RS22500	COG1454	alcohol dehydrogenase
GO175_RS22505	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GO175_RS22550	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GO175_RS22565	COG1609	Transcriptional regulator
GO175_RS22565	COG2207	Transcriptional regulator
GO175_RS22570	COG4604	ABC transporter, ATP-binding protein
GO175_RS22575	COG4605	iron ion homeostasis
GO175_RS22580	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO175_RS22600	COG3291	Pkd domain containing protein
GO175_RS22600	COG4412	M6 family metalloprotease domain protein
GO175_RS22605	COG5380	lipid catabolic process
GO175_RS22610	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GO175_RS22620	COG1522	sequence-specific DNA binding
GO175_RS22640	COG2814	Major facilitator Superfamily
GO175_RS22650	COG0840	transmembrane signaling receptor activity
GO175_RS22670	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GO175_RS22675	COG3279	Response regulator of the LytR AlgR family
GO175_RS22680	COG3275	phosphorelay sensor kinase activity
GO175_RS22685	COG4989	oxidoreductase activity
GO175_RS22700	COG0366	Alpha amylase catalytic
GO175_RS22705	COG3227	Zinc metalloprotease (Elastase)
GO175_RS22710	COG3047	cAMP biosynthetic process
GO175_RS22715	COG0071	Belongs to the small heat shock protein (HSP20) family
GO175_RS22725	COG0251	oxidation-reduction process
GO175_RS22735	COG0583	DNA-binding transcription factor activity
GO175_RS22740	COG2267	carboxylic ester hydrolase activity
GO175_RS22750	COG1132	(ABC) transporter
GO175_RS22755	COG1132	(ABC) transporter
GO175_RS22765	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GO175_RS22770	COG2246	polysaccharide biosynthetic process
GO175_RS22780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GO175_RS22790	COG0242	peptide deformylase activity
GO175_RS22800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO175_RS22805	COG2084	Dehydrogenase
GO175_RS22815	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GO175_RS22820	COG0583	DNA-binding transcription factor activity
GO175_RS22855	COG0583	DNA-binding transcription factor activity
GO175_RS22880	COG1063	alcohol dehydrogenase
GO175_RS22885	COG0156	8-amino-7-oxononanoate synthase activity
GO175_RS22890	COG1012	belongs to the aldehyde dehydrogenase family
GO175_RS22895	COG3284	Transcriptional regulator
GO175_RS22905	COG0346	lactoylglutathione lyase activity
GO175_RS22925	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GO175_RS22940	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GO175_RS22945	COG0363	glucosamine-6-phosphate deaminase activity
GO175_RS22950	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GO175_RS22965	COG0583	DNA-binding transcription factor activity
GO175_RS22985	COG0531	amino acid
GO175_RS23000	COG1473	amidohydrolase
GO175_RS23005	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GO175_RS23010	COG1929	Belongs to the glycerate kinase type-1 family
GO175_RS23015	COG2610	gluconate transmembrane transporter activity
GO175_RS23020	COG3835	regulator
GO175_RS23025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GO175_RS23030	COG4533	DNA binding
GO175_RS23045	COG0840	transmembrane signaling receptor activity
GO175_RS23100	COG4964	Belongs to the GSP D family
GO175_RS23140	COG0798	PFAM Bile acid sodium symporter