locus-tag	class	description
LUM42_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LUM42_RS00010	COG0592	DNA-directed DNA polymerase activity
LUM42_RS00020	COG0187	DNA topoisomerase II activity
LUM42_RS00030	COG0071	Belongs to the small heat shock protein (HSP20) family
LUM42_RS00035	COG3977	Valine--pyruvate aminotransferase
LUM42_RS00040	COG0751	glycine-tRNA ligase activity
LUM42_RS00045	COG0752	glycyl-tRNA synthetase alpha subunit
LUM42_RS00050	COG2119	membrane
LUM42_RS00060	COG0425	Belongs to the sulfur carrier protein TusA family
LUM42_RS00090	COG0604	alcohol dehydrogenase
LUM42_RS00105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LUM42_RS00110	COG3978	acetolactate synthase activity
LUM42_RS00215	COG1196	nuclear chromosome segregation
LUM42_RS00225	COG0204	Acyl-transferase
LUM42_RS00230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LUM42_RS00235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LUM42_RS00245	COG3084	Protein conserved in bacteria
LUM42_RS00250	COG4326	sporulation control protein
LUM42_RS00255	COG1272	protein, Hemolysin III
LUM42_RS00265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LUM42_RS00270	COG0569	domain protein
LUM42_RS00275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LUM42_RS00275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LUM42_RS00295	COG0758	DNA mediated transformation
LUM42_RS00300	COG2922	Belongs to the Smg family
LUM42_RS00305	COG0551	DNA topoisomerase type I activity
LUM42_RS00310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LUM42_RS00315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LUM42_RS00325	COG0408	coproporphyrinogen oxidase activity
LUM42_RS00330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LUM42_RS00340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LUM42_RS00380	COG0583	DNA-binding transcription factor activity
LUM42_RS00385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LUM42_RS00390	COG2960	long-chain fatty acid transporting porin activity
LUM42_RS00395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUM42_RS00400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUM42_RS00405	COG1309	transcriptional regulator
LUM42_RS00450	COG0747	negative chemotaxis
LUM42_RS00455	COG0601	transmembrane transport
LUM42_RS00460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LUM42_RS00495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUM42_RS00500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUM42_RS00515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LUM42_RS00520	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LUM42_RS00555	COG0210	DNA helicase
LUM42_RS00560	COG0405	Gamma-glutamyltransferase
LUM42_RS00565	COG1280	lysine exporter protein (LysE YggA)
LUM42_RS00575	COG2962	Rard protein
LUM42_RS00580	COG0514	ATP-dependent DNA helicase (RecQ)
LUM42_RS00595	COG1132	(ABC) transporter
LUM42_RS00600	COG4774	siderophore transport
LUM42_RS00605	COG1120	ATPase activity
LUM42_RS00610	COG4607	ABC-type enterochelin transport system periplasmic component
LUM42_RS00620	COG2862	Uncharacterized protein family, UPF0114
LUM42_RS00650	COG0328	RNA-DNA hybrid ribonuclease activity
LUM42_RS00655	COG1968	undecaprenyl-diphosphatase activity
LUM42_RS00665	COG0668	transmembrane transport
LUM42_RS00670	COG1742	UPF0060 membrane protein
LUM42_RS00685	COG1279	arginine transmembrane transporter activity
LUM42_RS00715	COG2003	Belongs to the UPF0758 family
LUM42_RS00740	COG0671	phosphoesterase, PA-phosphatase related
LUM42_RS00745	COG2194	sulfuric ester hydrolase activity
LUM42_RS00750	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LUM42_RS00755	COG0745	RESPONSE REGULATOR receiver
LUM42_RS00760	COG5002	protein histidine kinase activity
LUM42_RS00770	COG1561	YicC-like family, N-terminal region
LUM42_RS00775	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LUM42_RS00780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LUM42_RS00785	COG1560	Kdo2-lipid A biosynthetic process
LUM42_RS00790	COG1309	transcriptional regulator
LUM42_RS00805	COG2003	Belongs to the UPF0758 family
LUM42_RS00810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LUM42_RS00815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LUM42_RS00825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LUM42_RS00840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LUM42_RS00845	COG0438	transferase activity, transferring glycosyl groups
LUM42_RS00850	COG0438	transferase activity, transferring glycosyl groups
LUM42_RS00855	COG0463	Glycosyl transferase, family 2
LUM42_RS00860	COG0859	PFAM glycosyl transferase family 9
LUM42_RS00865	COG3642	lipopolysaccharide core region biosynthetic process
LUM42_RS00870	COG1519	Transferase
LUM42_RS00875	COG0859	PFAM glycosyl transferase family 9
LUM42_RS00880	COG0438	transferase activity, transferring glycosyl groups
LUM42_RS00890	COG1560	Kdo2-lipid A biosynthetic process
LUM42_RS00900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LUM42_RS00905	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUM42_RS00935	COG0489	protein tyrosine kinase activity
LUM42_RS00935	COG3206	protein involved in exopolysaccharide biosynthesis
LUM42_RS00955	COG5433	transposase activity
LUM42_RS00975	COG5433	transposase activity
LUM42_RS00985	COG2089	acid synthase
LUM42_RS01020	COG5433	transposase activity
LUM42_RS01050	COG1879	ABC-type sugar transport system periplasmic component
LUM42_RS01065	COG0582	viral genome integration into host DNA
LUM42_RS01130	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LUM42_RS01165	COG1573	uracil-dna glycosylase
LUM42_RS01170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LUM42_RS01175	COG3068	Protein conserved in bacteria
LUM42_RS01180	COG0668	transmembrane transport
LUM42_RS01185	COG1253	flavin adenine dinucleotide binding
LUM42_RS01190	COG0776	regulation of translation
LUM42_RS01200	COG0151	Belongs to the GarS family
LUM42_RS01205	COG0138	bifunctional purine biosynthesis protein purh
LUM42_RS01215	COG0789	Transcriptional regulator
LUM42_RS01220	COG1940	carbohydrate kinase activity
LUM42_RS01230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LUM42_RS01230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LUM42_RS01230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUM42_RS01235	COG2207	Transcriptional regulator
LUM42_RS01250	COG0840	transmembrane signaling receptor activity
LUM42_RS01285	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LUM42_RS01290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LUM42_RS01295	COG2264	protein methyltransferase activity
LUM42_RS01300	COG0439	Biotin carboxylase
LUM42_RS01305	COG0511	ligase activity, forming carbon-carbon bonds
LUM42_RS01310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LUM42_RS01315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LUM42_RS01330	COG2814	Major facilitator Superfamily
LUM42_RS01335	COG2205	protein histidine kinase activity
LUM42_RS01335	COG2198	Histidine kinase
LUM42_RS01335	COG0784	Response regulator, receiver
LUM42_RS01335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUM42_RS01340	COG0248	Ppx GppA phosphatase
LUM42_RS01345	COG0513	Belongs to the DEAD box helicase family
LUM42_RS01350	COG3118	belongs to the thioredoxin family
LUM42_RS01365	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LUM42_RS01410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LUM42_RS01420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LUM42_RS01430	COG1072	(Pantothenic acid kinase))
LUM42_RS01460	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LUM42_RS01465	COG0250	Participates in transcription elongation, termination and antitermination
LUM42_RS01480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LUM42_RS01485	COG0222	ribosome binding
LUM42_RS01490	COG0085	RNA polymerase activity
LUM42_RS01495	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LUM42_RS01500	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LUM42_RS01505	COG2816	NAD+ diphosphatase activity
LUM42_RS01510	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LUM42_RS01525	COG4942	peptidase
LUM42_RS01530	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LUM42_RS01540	COG0840	transmembrane signaling receptor activity
LUM42_RS01545	COG0490	domain, Protein
LUM42_RS01545	COG0471	metal ion transport
LUM42_RS01550	COG0688	phosphatidylethanolamine metabolic process
LUM42_RS01555	COG1162	GTPase activity
LUM42_RS01610	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LUM42_RS01615	COG0802	atpase or kinase
LUM42_RS01625	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LUM42_RS01630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LUM42_RS01640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LUM42_RS01645	COG0330	HflC and HflK could
LUM42_RS01650	COG0330	HflC and HflK could
LUM42_RS01655	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LUM42_RS01660	COG2900	Belongs to the SlyX family
LUM42_RS01670	COG0545	Peptidyl-prolyl cis-trans isomerase
LUM42_RS01675	COG2964	Protein conserved in bacteria
LUM42_RS01685	COG2923	Belongs to the DsrF TusC family
LUM42_RS01690	COG2168	tRNA wobble position uridine thiolation
LUM42_RS01700	COG0049	tRNA binding
LUM42_RS01705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LUM42_RS01715	COG2906	2 iron, 2 sulfur cluster binding
LUM42_RS01725	COG0360	Binds together with S18 to 16S ribosomal RNA
LUM42_RS01730	COG2965	DNA replication, synthesis of RNA primer
LUM42_RS01740	COG0359	binds to the 23S rRNA
LUM42_RS01755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LUM42_RS01765	COG0166	Belongs to the GPI family
LUM42_RS01775	COG0735	belongs to the Fur family
LUM42_RS01780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LUM42_RS01800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LUM42_RS01810	COG0175	sulfate reduction
LUM42_RS01875	COG0646	methionine synthase
LUM42_RS01875	COG1410	methionine synthase
LUM42_RS01880	COG0527	aspartate kinase activity
LUM42_RS01885	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LUM42_RS01895	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LUM42_RS01910	COG0629	single-stranded DNA binding
LUM42_RS01915	COG2200	EAL domain
LUM42_RS01915	COG2199	diguanylate cyclase activity
LUM42_RS01940	COG3409	Peptidoglycan-binding domain 1 protein
LUM42_RS01940	COG3267	Type II secretory pathway component ExeA
LUM42_RS01950	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LUM42_RS01955	COG1459	type II secretion system
LUM42_RS01965	COG2165	general secretion pathway protein
LUM42_RS01970	COG2165	general secretion pathway protein
LUM42_RS02000	COG1077	Cell shape determining protein MreB Mrl
LUM42_RS02005	COG1792	Involved in formation and maintenance of cell shape
LUM42_RS02010	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LUM42_RS02015	COG0424	maF-like protein
LUM42_RS02020	COG1530	ribonuclease E activity
LUM42_RS02025	COG3164	Protein of unknown function
LUM42_RS02030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LUM42_RS02035	COG0312	modulator of DNA gyrase
LUM42_RS02055	COG0589	response to stress
LUM42_RS02070	COG1438	arginine binding
LUM42_RS02075	COG0039	L-malate dehydrogenase activity
LUM42_RS02080	COG0531	amino acid
LUM42_RS02085	COG0142	geranyltranstransferase activity
LUM42_RS02090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LUM42_RS02100	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LUM42_RS02105	COG2966	Psort location CytoplasmicMembrane, score
LUM42_RS02110	COG3610	response to peptide
LUM42_RS02120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LUM42_RS02125	COG2967	ApaG domain
LUM42_RS02130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LUM42_RS02135	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LUM42_RS02140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LUM42_RS02145	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LUM42_RS02150	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LUM42_RS02200	COG0741	lytic transglycosylase activity
LUM42_RS02205	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LUM42_RS02215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LUM42_RS02220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_RS02225	COG1120	ATPase activity
LUM42_RS02230	COG1194	a g-specific adenine glycosylase
LUM42_RS02235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LUM42_RS02240	COG2066	Belongs to the glutaminase family
LUM42_RS02245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LUM42_RS02250	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LUM42_RS02260	COG1872	DUF167
LUM42_RS02265	COG0762	integral membrane protein
LUM42_RS02270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LUM42_RS02275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LUM42_RS02290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LUM42_RS02295	COG1678	Uncharacterized ACR, COG1678
LUM42_RS02300	COG0189	ligase activity
LUM42_RS02305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LUM42_RS02310	COG2356	endonuclease I
LUM42_RS02325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LUM42_RS02330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LUM42_RS02335	COG0583	DNA-binding transcription factor activity
LUM42_RS02340	COG4771	TonB-dependent receptor
LUM42_RS02345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LUM42_RS02350	COG0126	phosphoglycerate kinase activity
LUM42_RS02355	COG0191	fructose-bisphosphate aldolase activity
LUM42_RS02360	COG0668	transmembrane transport
LUM42_RS02370	COG1279	arginine transmembrane transporter activity
LUM42_RS02395	COG1349	DNA-binding transcription factor activity
LUM42_RS02400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LUM42_RS02415	COG2239	Acts as a magnesium transporter
LUM42_RS02425	COG1609	Transcriptional regulator
LUM42_RS02430	COG1263	PTS System
LUM42_RS02430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUM42_RS02435	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LUM42_RS02445	COG2378	regulation of single-species biofilm formation
LUM42_RS02460	COG1278	Cold shock
LUM42_RS02515	COG0358	DNA primase activity
LUM42_RS02520	COG1610	YqeY-like protein
LUM42_RS02525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LUM42_RS02530	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LUM42_RS02540	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LUM42_RS02545	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LUM42_RS02550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LUM42_RS02555	COG1968	undecaprenyl-diphosphatase activity
LUM42_RS02560	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LUM42_RS02565	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LUM42_RS02575	COG0585	pseudouridine synthase activity
LUM42_RS02580	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LUM42_RS02585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LUM42_RS02590	COG1388	LysM domain
LUM42_RS02590	COG4942	peptidase
LUM42_RS02595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LUM42_RS02600	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LUM42_RS02605	COG1546	Belongs to the CinA family
LUM42_RS02610	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LUM42_RS02615	COG2137	regulation of response to DNA damage stimulus
LUM42_RS02620	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LUM42_RS02625	COG0527	aspartate kinase activity
LUM42_RS02675	COG3630	sodium ion export across plasma membrane
LUM42_RS02680	COG0511	ligase activity, forming carbon-carbon bonds
LUM42_RS02680	COG5016	pyruvate
LUM42_RS02685	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
LUM42_RS02695	COG1238	metal cluster binding
LUM42_RS02700	COG0612	Peptidase, M16
LUM42_RS02705	COG2918	glutathione biosynthetic process
LUM42_RS02715	COG1854	S-ribosylhomocysteine lyase activity
LUM42_RS02720	COG4536	flavin adenine dinucleotide binding
LUM42_RS02725	COG4137	Cytochrome C assembly protein
LUM42_RS02730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LUM42_RS02740	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LUM42_RS02745	COG0336	Belongs to the RNA methyltransferase TrmD family
LUM42_RS02750	COG0335	large ribosomal subunit rRNA binding
LUM42_RS02755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUM42_RS02760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUM42_RS02765	COG3105	Protein conserved in bacteria
LUM42_RS02770	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LUM42_RS02775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LUM42_RS02780	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LUM42_RS02785	COG0723	plastoquinol--plastocyanin reductase activity
LUM42_RS02790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LUM42_RS02795	COG2857	Cytochrome c1
LUM42_RS02800	COG0625	glutathione transferase activity
LUM42_RS02805	COG2969	positive regulation of protein catabolic process
LUM42_RS02810	COG2823	Periplasmic or secreted lipoprotein
LUM42_RS02815	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LUM42_RS02820	COG0792	nuclease activity
LUM42_RS02825	COG3107	peptidoglycan biosynthetic process
LUM42_RS02830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LUM42_RS02845	COG3116	cell division
LUM42_RS02850	COG0768	penicillin binding
LUM42_RS02855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LUM42_RS02860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LUM42_RS02870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LUM42_RS02875	COG0772	Belongs to the SEDS family
LUM42_RS02880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LUM42_RS02885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LUM42_RS02890	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LUM42_RS02895	COG0849	cell division
LUM42_RS02900	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LUM42_RS02905	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LUM42_RS02915	COG0653	protein targeting
LUM42_RS02920	COG0494	nUDIX hydrolase
LUM42_RS02925	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LUM42_RS02930	COG0505	Belongs to the CarA family
LUM42_RS02935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LUM42_RS02945	COG3479	Phenolic acid decarboxylase
LUM42_RS02950	COG0730	response to heat
LUM42_RS02955	COG0583	DNA-binding transcription factor activity
LUM42_RS02975	COG2860	membrane
LUM42_RS02980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LUM42_RS02990	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LUM42_RS03000	COG0493	'glutamate synthase
LUM42_RS03005	COG0070	glutamate synthase
LUM42_RS03005	COG0069	glutamate synthase activity
LUM42_RS03005	COG0067	glutamate synthase
LUM42_RS03015	COG0070	glutamate synthase
LUM42_RS03015	COG0069	glutamate synthase activity
LUM42_RS03015	COG0067	glutamate synthase
LUM42_RS03020	COG1242	4 iron, 4 sulfur cluster binding
LUM42_RS03025	COG5001	Diguanylate cyclase
LUM42_RS03025	COG4251	negative regulation of phosphorylation
LUM42_RS03025	COG3706	GGDEF domain
LUM42_RS03025	COG2203	Gaf domain
LUM42_RS03030	COG5002	protein histidine kinase activity
LUM42_RS03030	COG0784	Response regulator, receiver
LUM42_RS03030	COG2198	Histidine kinase
LUM42_RS03040	COG0745	RESPONSE REGULATOR receiver
LUM42_RS03050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LUM42_RS03065	COG0083	homoserine kinase activity
LUM42_RS03070	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LUM42_RS03075	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LUM42_RS03090	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LUM42_RS03105	COG1115	amino acid carrier protein
LUM42_RS03110	COG3022	response to hydroperoxide
LUM42_RS03120	COG0084	hydrolase, TatD family'
LUM42_RS03125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LUM42_RS03135	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LUM42_RS03140	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LUM42_RS03145	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LUM42_RS03150	COG0813	purine-nucleoside phosphorylase activity
LUM42_RS03160	COG0560	Phosphoserine phosphatase
LUM42_RS03170	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LUM42_RS03175	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LUM42_RS03180	COG0583	DNA-binding transcription factor activity
LUM42_RS03190	COG0583	DNA-binding transcription factor activity
LUM42_RS03195	COG1022	Amp-dependent synthetase and ligase
LUM42_RS03230	COG4964	Belongs to the GSP D family
LUM42_RS03285	COG2059	Chromate
LUM42_RS03290	COG2017	converts alpha-aldose to the beta-anomer
LUM42_RS03295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LUM42_RS03325	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LUM42_RS03330	COG2171	N-acyltransferase activity
LUM42_RS03335	COG3141	response to X-ray
LUM42_RS03340	COG0583	DNA-binding transcription factor activity
LUM42_RS03350	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LUM42_RS03355	COG1074	ATP-dependent DNA helicase activity
LUM42_RS03360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LUM42_RS03370	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LUM42_RS03370	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LUM42_RS03380	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LUM42_RS03385	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LUM42_RS03390	COG2166	iron-sulfur cluster assembly
LUM42_RS03395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LUM42_RS03400	COG0693	protein deglycase activity
LUM42_RS03405	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LUM42_RS03410	COG3248	Nucleoside-binding outer membrane protein
LUM42_RS03420	COG1595	DNA-templated transcription, initiation
LUM42_RS03430	COG0477	Major facilitator Superfamily
LUM42_RS03435	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LUM42_RS03440	COG0826	peptidase U32
LUM42_RS03450	COG0745	RESPONSE REGULATOR receiver
LUM42_RS03455	COG5002	protein histidine kinase activity
LUM42_RS03465	COG0248	Ppx GppA phosphatase
LUM42_RS03470	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LUM42_RS03475	COG0573	inorganic phosphate transmembrane transporter activity
LUM42_RS03480	COG0581	inorganic phosphate transmembrane transporter activity
LUM42_RS03485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LUM42_RS03490	COG0704	Plays a role in the regulation of phosphate uptake
LUM42_RS03500	COG3142	Participates in the control of copper homeostasis
LUM42_RS03505	COG0450	alkyl hydroperoxide reductase
LUM42_RS03510	COG0583	DNA-binding transcription factor activity
LUM42_RS03515	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LUM42_RS03530	COG0517	IMP dehydrogenase activity
LUM42_RS03535	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LUM42_RS03545	COG1862	Preprotein translocase
LUM42_RS03550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUM42_RS03555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUM42_RS03560	COG1335	isochorismatase
LUM42_RS03565	COG0483	inositol monophosphate 1-phosphatase activity
LUM42_RS03570	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LUM42_RS03575	COG1959	2 iron, 2 sulfur cluster binding
LUM42_RS03580	COG1104	cysteine desulfurase activity
LUM42_RS03585	COG0822	iron-sulfur transferase activity
LUM42_RS03600	COG0443	Heat shock 70 kDa protein
LUM42_RS03605	COG0633	Ferredoxin
LUM42_RS03610	COG2975	iron-sulfur cluster assembly
LUM42_RS03615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LUM42_RS03620	COG0105	UTP biosynthetic process
LUM42_RS03635	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LUM42_RS03640	COG0124	histidyl-tRNA synthetase
LUM42_RS03645	COG2976	Protein conserved in bacteria
LUM42_RS03650	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUM42_RS03655	COG1160	GTP binding
LUM42_RS03670	COG1570	exodeoxyribonuclease VII activity
LUM42_RS03675	COG0516	GMP reductase activity
LUM42_RS03675	COG0517	IMP dehydrogenase activity
LUM42_RS03680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LUM42_RS03680	COG0519	Catalyzes the synthesis of GMP from XMP
LUM42_RS03690	COG1584	GPR1 FUN34 yaaH family protein
LUM42_RS03700	COG3710	Transcriptional regulator
LUM42_RS03710	COG3188	usher protein
LUM42_RS03715	COG3121	Chaperone
LUM42_RS03735	COG1115	amino acid carrier protein
LUM42_RS03750	COG0583	DNA-binding transcription factor activity
LUM42_RS03755	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LUM42_RS03785	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LUM42_RS03790	COG2867	negative regulation of translational initiation
LUM42_RS03795	COG2914	Belongs to the UPF0125 (RnfH) family
LUM42_RS03800	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUM42_RS03805	COG0497	DNA recombination
LUM42_RS03810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LUM42_RS03815	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LUM42_RS03825	COG0443	Heat shock 70 kDa protein
LUM42_RS03830	COG0484	heat shock protein binding
LUM42_RS03840	COG4969	Belongs to the N-Me-Phe pilin family
LUM42_RS03860	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LUM42_RS03865	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LUM42_RS03875	COG0583	DNA-binding transcription factor activity
LUM42_RS03885	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LUM42_RS03890	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LUM42_RS03890	COG0047	phosphoribosylformylglycinamidine synthase activity
LUM42_RS03915	COG0442	prolyl-tRNA aminoacylation
LUM42_RS03920	COG1720	tRNA m6t6A37 methyltransferase activity
LUM42_RS03925	COG0254	rRNA binding
LUM42_RS03930	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LUM42_RS03935	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LUM42_RS03940	COG1671	Belongs to the UPF0178 family
LUM42_RS03965	COG3098	single-species biofilm formation
LUM42_RS03970	COG0564	pseudouridine synthase activity
LUM42_RS03975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LUM42_RS03980	COG0142	geranyltranstransferase activity
LUM42_RS03985	COG1722	exodeoxyribonuclease VII activity
LUM42_RS03990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LUM42_RS04000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LUM42_RS04000	COG0301	tRNA thio-modification
LUM42_RS04005	COG0583	DNA-binding transcription factor activity
LUM42_RS04015	COG2363	Small membrane protein
LUM42_RS04025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LUM42_RS04030	COG1611	Belongs to the LOG family
LUM42_RS04045	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LUM42_RS04045	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LUM42_RS04055	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
LUM42_RS04060	COG1464	Belongs to the NlpA lipoprotein family
LUM42_RS04065	COG2011	ABC-type metal ion transport system permease component
LUM42_RS04070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LUM42_RS04075	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LUM42_RS04090	COG1263	PTS System
LUM42_RS04090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUM42_RS04095	COG0366	Alpha amylase catalytic
LUM42_RS04100	COG2271	Major facilitator Superfamily
LUM42_RS04105	COG3851	Histidine kinase
LUM42_RS04110	COG2197	response regulator
LUM42_RS04140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUM42_RS04145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUM42_RS04155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LUM42_RS04165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LUM42_RS04170	COG0321	lipoyl(octanoyl) transferase activity
LUM42_RS04175	COG2921	Belongs to the UPF0250 family
LUM42_RS04180	COG1686	Belongs to the peptidase S11 family
LUM42_RS04185	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LUM42_RS04190	COG0772	Belongs to the SEDS family
LUM42_RS04195	COG0768	penicillin binding
LUM42_RS04200	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LUM42_RS04205	COG0799	negative regulation of ribosome biogenesis
LUM42_RS04210	COG1466	dna polymerase III delta subunit
LUM42_RS04215	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LUM42_RS04220	COG0495	leucyl-tRNA aminoacylation
LUM42_RS04225	COG2888	peptidyl-tyrosine sulfation
LUM42_RS04230	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LUM42_RS04235	COG4535	Mg2 and Co2 transporter CorC
LUM42_RS04240	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LUM42_RS04245	COG1702	phosphate starvation-inducible protein PhoH
LUM42_RS04250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LUM42_RS04255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUM42_RS04260	COG2190	(PTS) system
LUM42_RS04270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUM42_RS04275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LUM42_RS04280	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LUM42_RS04285	COG3115	cell septum assembly
LUM42_RS04290	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LUM42_RS04305	COG0789	Transcriptional regulator
LUM42_RS04315	COG0330	HflC and HflK could
LUM42_RS04320	COG3118	belongs to the thioredoxin family
LUM42_RS04325	COG0300	oxidoreductase activity
LUM42_RS04330	COG1090	epimerase
LUM42_RS04355	COG0622	Phosphoesterase
LUM42_RS04370	COG3710	Transcriptional regulator
LUM42_RS04385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LUM42_RS04400	COG0367	asparagine synthase
LUM42_RS04405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LUM42_RS04405	COG4651	solute:proton antiporter activity
LUM42_RS04410	COG1846	Transcriptional regulator
LUM42_RS04410	COG1940	carbohydrate kinase activity
LUM42_RS04415	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LUM42_RS04420	COG2190	(PTS) system
LUM42_RS04420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUM42_RS04420	COG1263	PTS System
LUM42_RS04435	COG0101	tRNA pseudouridine synthase activity
LUM42_RS04440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LUM42_RS04445	COG0285	dihydrofolate synthase activity
LUM42_RS04450	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LUM42_RS04455	COG1286	toxin biosynthetic process
LUM42_RS04460	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LUM42_RS04465	COG2056	Na+-H+ antiporter family
LUM42_RS04470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LUM42_RS04485	COG0346	lactoylglutathione lyase activity
LUM42_RS04490	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LUM42_RS04495	COG4660	Part of a membrane complex involved in electron transport
LUM42_RS04500	COG4659	FMN binding
LUM42_RS04505	COG4658	electron transport chain
LUM42_RS04510	COG4656	Part of a membrane complex involved in electron transport
LUM42_RS04515	COG2878	Part of a membrane complex involved in electron transport
LUM42_RS04520	COG4657	Part of a membrane complex involved in electron transport
LUM42_RS04525	COG1882	Formate acetyltransferase
LUM42_RS04535	COG0556	nucleotide-excision repair
LUM42_RS04540	COG2204	response regulator
LUM42_RS04545	COG2198	Histidine kinase
LUM42_RS04550	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LUM42_RS04555	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LUM42_RS04560	COG0521	Mo-molybdopterin cofactor biosynthetic process
LUM42_RS04565	COG0315	cyclic pyranopterin monophosphate synthase activity
LUM42_RS04570	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LUM42_RS04575	COG0314	molybdopterin synthase activity
LUM42_RS04580	COG3706	GGDEF domain
LUM42_RS04585	COG0517	IMP dehydrogenase activity
LUM42_RS04585	COG0617	tRNA 3'-terminal CCA addition
LUM42_RS04585	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LUM42_RS04595	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
LUM42_RS04605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LUM42_RS04605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LUM42_RS04615	COG0572	uridine kinase
LUM42_RS04620	COG2982	Protein involved in outer membrane biogenesis
LUM42_RS04625	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LUM42_RS04645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LUM42_RS04650	COG2067	long-chain fatty acid transport protein
LUM42_RS04670	COG0183	Belongs to the thiolase family
LUM42_RS04675	COG1024	Enoyl-CoA hydratase
LUM42_RS04675	COG1250	3-hydroxyacyl-CoA dehydrogenase
LUM42_RS04680	COG0778	Nitroreductase
LUM42_RS04685	COG0583	DNA-binding transcription factor activity
LUM42_RS04690	COG0745	RESPONSE REGULATOR receiver
LUM42_RS04695	COG2832	Protein of unknown function (DUF454)
LUM42_RS04700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LUM42_RS04710	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LUM42_RS04715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LUM42_RS04720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LUM42_RS04730	COG2983	Belongs to the UPF0260 family
LUM42_RS04745	COG2226	methyltransferase
LUM42_RS04750	COG0676	glucose-6-phosphate 1-epimerase activity
LUM42_RS04755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LUM42_RS04760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LUM42_RS04770	COG3139	Protein of unknown function (DUF1315)
LUM42_RS04775	COG0252	asparaginase activity
LUM42_RS04780	COG0616	signal peptide processing
LUM42_RS04785	COG1902	pentaerythritol trinitrate reductase activity
LUM42_RS04785	COG0446	pyridine nucleotide-disulphide oxidoreductase
LUM42_RS04790	COG0788	formyltetrahydrofolate deformylase activity
LUM42_RS04800	COG1199	ATP-dependent helicase activity
LUM42_RS04805	COG1214	PFAM Peptidase M22, glycoprotease
LUM42_RS04820	COG2267	carboxylic ester hydrolase activity
LUM42_RS04825	COG0318	PFAM AMP-dependent synthetase and ligase
LUM42_RS04830	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LUM42_RS04840	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LUM42_RS04845	COG2894	cell division
LUM42_RS04850	COG0850	regulation of cytokinetic process
LUM42_RS04855	COG3100	YcgL domain-containing protein
LUM42_RS04860	COG2951	lytic endotransglycosylase activity
LUM42_RS04870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LUM42_RS04875	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LUM42_RS04890	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LUM42_RS04895	COG2211	Major facilitator Superfamily
LUM42_RS04940	COG4589	Belongs to the CDS family
LUM42_RS04960	COG3153	acetyltransferase
LUM42_RS04960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LUM42_RS04970	COG1760	l-serine dehydratase
LUM42_RS04975	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LUM42_RS04995	COG1404	Belongs to the peptidase S8 family
LUM42_RS05000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LUM42_RS05005	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LUM42_RS05010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LUM42_RS05015	COG2204	response regulator
LUM42_RS05020	COG4191	Histidine kinase
LUM42_RS05030	COG0544	peptidyl-prolyl cis-trans isomerase activity
LUM42_RS05040	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LUM42_RS05045	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LUM42_RS05050	COG0776	regulation of translation
LUM42_RS05055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LUM42_RS05060	COG1555	photosystem II stabilization
LUM42_RS05065	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LUM42_RS05070	COG0539	negative regulation of cytoplasmic translation
LUM42_RS05075	COG0776	regulation of translation
LUM42_RS05080	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LUM42_RS05085	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LUM42_RS05105	COG0583	DNA-binding transcription factor activity
LUM42_RS05115	COG0686	Belongs to the AlaDH PNT family
LUM42_RS05120	COG1522	sequence-specific DNA binding
LUM42_RS05125	COG1674	ftsk spoiiie
LUM42_RS05130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LUM42_RS05135	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LUM42_RS05140	COG2186	Transcriptional regulator
LUM42_RS05155	COG0537	adenosine 5'-monophosphoramidase activity
LUM42_RS05180	COG3150	esterase
LUM42_RS05185	COG1252	NADH dehydrogenase
LUM42_RS05200	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LUM42_RS05210	COG4591	ABC-type transport system involved in lipoprotein release permease component
LUM42_RS05215	COG1136	(ABC) transporter
LUM42_RS05220	COG4591	ABC-type transport system involved in lipoprotein release permease component
LUM42_RS05230	COG0658	competence protein
LUM42_RS05230	COG2333	competence protein COMEC
LUM42_RS05235	COG1132	(ABC) transporter
LUM42_RS05240	COG1663	tetraacyldisaccharide 4'-kinase activity
LUM42_RS05250	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LUM42_RS05255	COG2719	SpoVR family
LUM42_RS05260	COG2718	Belongs to the UPF0229 family
LUM42_RS05265	COG2766	serine protein kinase
LUM42_RS05270	COG3713	MltA-interacting MipA family protein
LUM42_RS05275	COG3013	Belongs to the UPF0304 family
LUM42_RS05285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LUM42_RS05300	COG1882	Formate acetyltransferase
LUM42_RS05325	COG4160	amino acid transport
LUM42_RS05330	COG0708	Exodeoxyribonuclease III
LUM42_RS05335	COG0840	transmembrane signaling receptor activity
LUM42_RS05345	COG3923	Primosomal replication protein n
LUM42_RS05350	COG1199	ATP-dependent helicase activity
LUM42_RS05355	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LUM42_RS05360	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LUM42_RS05365	COG3012	SEC-C Motif Domain Protein
LUM42_RS05370	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LUM42_RS05375	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LUM42_RS05380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LUM42_RS05385	COG0215	cysteine-tRNA ligase activity
LUM42_RS05390	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LUM42_RS05395	COG0632	four-way junction helicase activity
LUM42_RS05400	COG2255	four-way junction helicase activity
LUM42_RS05405	COG1271	oxidase subunit
LUM42_RS05410	COG1294	oxidase, subunit
LUM42_RS05415	COG4890	Cyd operon protein YbgT
LUM42_RS05425	COG0824	Thioesterase
LUM42_RS05430	COG0811	peptide transport
LUM42_RS05445	COG0823	Involved in the tonB-independent uptake of proteins
LUM42_RS05450	COG2885	chlorophyll binding
LUM42_RS05455	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LUM42_RS05460	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LUM42_RS05470	COG0784	Response regulator, receiver
LUM42_RS05470	COG5002	protein histidine kinase activity
LUM42_RS05495	COG3366	ferrous iron transmembrane transporter activity
LUM42_RS05500	COG0700	Nucleoside recognition
LUM42_RS05505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LUM42_RS05510	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_RS05530	COG1960	acyl-CoA dehydrogenase activity
LUM42_RS05535	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LUM42_RS05545	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LUM42_RS05555	COG1737	Transcriptional regulator
LUM42_RS05560	COG0076	glutamate decarboxylase activity
LUM42_RS05570	COG2431	L-lysine efflux transmembrane transporter activity
LUM42_RS05580	COG3070	regulator of competence-specific genes
LUM42_RS05595	COG4191	Histidine kinase
LUM42_RS05595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUM42_RS05605	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LUM42_RS05610	COG1053	succinate dehydrogenase
LUM42_RS05625	COG3940	Belongs to the glycosyl hydrolase 43 family
LUM42_RS05630	COG2211	Major facilitator Superfamily
LUM42_RS05635	COG1032	radical SAM domain protein
LUM42_RS05640	COG0488	(ABC) transporter
LUM42_RS05650	COG0346	lactoylglutathione lyase activity
LUM42_RS05670	COG0583	DNA-binding transcription factor activity
LUM42_RS05680	COG0840	transmembrane signaling receptor activity
LUM42_RS05685	COG2200	EAL domain
LUM42_RS05685	COG2771	luxR family
LUM42_RS05700	COG0612	Peptidase, M16
LUM42_RS05715	COG0583	DNA-binding transcription factor activity
LUM42_RS05750	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LUM42_RS05760	COG1815	bacterial-type flagellum-dependent cell motility
LUM42_RS05765	COG1558	bacterial-type flagellum-dependent cell motility
LUM42_RS05770	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LUM42_RS05775	COG1749	Flagellar hook protein flgE
LUM42_RS05785	COG4786	Flagellar basal body rod
LUM42_RS05790	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LUM42_RS05795	COG1706	bacterial-type flagellum-dependent cell motility
LUM42_RS05820	COG1677	Flagellar hook-basal body complex protein FliE
LUM42_RS05830	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LUM42_RS05860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUM42_RS05865	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUM42_RS05870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUM42_RS05875	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LUM42_RS05905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LUM42_RS05910	COG1360	Flagellar Motor Protein
LUM42_RS05920	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LUM42_RS05935	COG2350	Protein conserved in bacteria
LUM42_RS05950	COG1301	dicarboxylic acid transport
LUM42_RS05955	COG0159	tryptophan synthase activity
LUM42_RS05960	COG0133	tryptophan synthase activity
LUM42_RS05965	COG0135	phosphoribosylanthranilate isomerase activity
LUM42_RS05965	COG0134	indole-3-glycerol-phosphate synthase activity
LUM42_RS05970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LUM42_RS05975	COG0512	Glutamine amidotransferase of anthranilate synthase
LUM42_RS05980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LUM42_RS05990	COG0613	PHP domain protein
LUM42_RS05995	COG1737	Transcriptional regulator
LUM42_RS05995	COG0837	glucose binding
LUM42_RS06005	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LUM42_RS06015	COG4145	pantothenate transmembrane transporter activity
LUM42_RS06020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUM42_RS06025	COG0800	Aldolase
LUM42_RS06035	COG0009	L-threonylcarbamoyladenylate synthase
LUM42_RS06040	COG1187	pseudouridine synthase activity
LUM42_RS06050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LUM42_RS06055	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LUM42_RS06060	COG4988	ABC transporter
LUM42_RS06065	COG0492	ferredoxin-NADP+ reductase activity
LUM42_RS06085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LUM42_RS06095	COG2949	membrane
LUM42_RS06120	COG0583	DNA-binding transcription factor activity
LUM42_RS06130	COG0281	malic enzyme
LUM42_RS06135	COG1643	Atp-dependent helicase
LUM42_RS06150	COG0583	DNA-binding transcription factor activity
LUM42_RS06165	COG1757	Na H antiporter
LUM42_RS06170	COG0174	glutamine synthetase
LUM42_RS06175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LUM42_RS06180	COG1917	Cupin 2, conserved barrel domain protein
LUM42_RS06180	COG1396	sequence-specific DNA binding
LUM42_RS06185	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_RS06190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUM42_RS06200	COG2957	Belongs to the agmatine deiminase family
LUM42_RS06210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUM42_RS06215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LUM42_RS06235	COG2885	chlorophyll binding
LUM42_RS06250	COG0277	FAD linked oxidase domain protein
LUM42_RS06250	COG0247	lactate metabolic process
LUM42_RS06270	COG2986	histidine ammonia-lyase
LUM42_RS06280	COG0010	Belongs to the arginase family
LUM42_RS06285	COG1228	amidohydrolase
LUM42_RS06300	COG3099	Belongs to the UPF0263 family
LUM42_RS06305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LUM42_RS06315	COG0417	DNA replication proofreading
LUM42_RS06320	COG2197	response regulator
LUM42_RS06325	COG0322	excinuclease ABC activity
LUM42_RS06355	COG2133	pyrroloquinoline quinone binding
LUM42_RS06375	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LUM42_RS06380	COG0072	phenylalanine-tRNA ligase activity
LUM42_RS06380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LUM42_RS06385	COG0776	regulation of translation
LUM42_RS06395	COG0500	methyltransferase
LUM42_RS06425	COG5001	Diguanylate cyclase
LUM42_RS06430	COG0295	cytidine deaminase activity
LUM42_RS06435	COG1346	cytolysis
LUM42_RS06440	COG1380	Effector of murein hydrolase LrgA
LUM42_RS06445	COG2925	Exonuclease
LUM42_RS06470	COG1823	symporter activity
LUM42_RS06480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LUM42_RS06485	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LUM42_RS06490	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LUM42_RS06505	COG2988	succinylglutamate desuccinylase activity
LUM42_RS06510	COG4139	cobalamin transport
LUM42_RS06515	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
LUM42_RS06585	COG4964	Belongs to the GSP D family
LUM42_RS06630	COG1609	Transcriptional regulator
LUM42_RS06640	COG2182	Extracellular solute-binding protein
LUM42_RS06645	COG1175	transmembrane transport
LUM42_RS06650	COG3833	ABC-type maltose transport systems, permease component
LUM42_RS06660	COG1874	Beta-galactosidase
LUM42_RS06675	COG0110	maltose O-acetyltransferase activity
LUM42_RS06700	COG0583	DNA-binding transcription factor activity
LUM42_RS06710	COG1451	nucleotide metabolic process
LUM42_RS06725	COG3063	Type IV pilus biogenesis stability protein PilW
LUM42_RS06730	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LUM42_RS06750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUM42_RS06765	COG3290	protein histidine kinase activity
LUM42_RS06770	COG4565	transcriptional regulatory protein
LUM42_RS06780	COG0784	Response regulator, receiver
LUM42_RS06780	COG0835	chemotaxis
LUM42_RS06790	COG1921	L-seryl-tRNASec selenium transferase activity
LUM42_RS06800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LUM42_RS06805	COG0651	ATP synthesis coupled electron transport
LUM42_RS06810	COG0650	Formate hydrogenlyase subunit 4
LUM42_RS06815	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LUM42_RS06815	COG3261	NADH dehydrogenase
LUM42_RS06820	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LUM42_RS06825	COG3260	NADH ubiquinone oxidoreductase 20
LUM42_RS06835	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LUM42_RS06840	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LUM42_RS06850	COG3604	Transcriptional regulator
LUM42_RS06855	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LUM42_RS06865	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LUM42_RS06870	COG0298	carbon dioxide binding
LUM42_RS06880	COG0309	Hydrogenase expression formation protein (HypE)
LUM42_RS06885	COG0375	protein maturation
LUM42_RS06890	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LUM42_RS06895	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LUM42_RS06900	COG2897	thiosulfate sulfurtransferase activity
LUM42_RS06950	COG0668	transmembrane transport
LUM42_RS06970	COG0745	RESPONSE REGULATOR receiver
LUM42_RS06975	COG5002	protein histidine kinase activity
LUM42_RS07000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LUM42_RS07010	COG3391	amine dehydrogenase activity
LUM42_RS07015	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LUM42_RS07020	COG1254	Belongs to the acylphosphatase family
LUM42_RS07025	COG2920	part of a sulfur-relay system
LUM42_RS07030	COG0670	Belongs to the BI1 family
LUM42_RS07035	COG1126	abc transporter atp-binding protein
LUM42_RS07040	COG0765	amino acid transport
LUM42_RS07045	COG4597	amino acid ABC transporter
LUM42_RS07050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUM42_RS07060	COG0561	phosphatase activity
LUM42_RS07065	COG0602	queuosine metabolic process
LUM42_RS07070	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LUM42_RS07075	COG3005	denitrification pathway
LUM42_RS07080	COG0243	molybdopterin cofactor binding
LUM42_RS07085	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
LUM42_RS07090	COG0657	acetylesterase activity
LUM42_RS07095	COG2999	glutathione oxidoreductase activity
LUM42_RS07125	COG0443	Heat shock 70 kDa protein
LUM42_RS07140	COG3706	GGDEF domain
LUM42_RS07170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LUM42_RS07175	COG1643	Atp-dependent helicase
LUM42_RS07210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LUM42_RS07240	COG4638	Rieske (2fe-2S)
LUM42_RS07245	COG0583	DNA-binding transcription factor activity
LUM42_RS07250	COG1414	Transcriptional regulator
LUM42_RS07270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_RS07275	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_RS07280	COG1120	ATPase activity
LUM42_RS07285	COG0583	DNA-binding transcription factor activity
LUM42_RS07290	COG4774	siderophore transport
LUM42_RS07295	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LUM42_RS07305	COG3501	Rhs element vgr protein
LUM42_RS07330	COG1115	amino acid carrier protein
LUM42_RS07345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LUM42_RS07350	COG1666	GTP binding
LUM42_RS07355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LUM42_RS07375	COG2996	Protein conserved in bacteria
LUM42_RS07385	COG3008	intermembrane lipid transfer
LUM42_RS07390	COG2995	paraquat-inducible protein a
LUM42_RS07395	COG1132	(ABC) transporter
LUM42_RS07400	COG1956	GAF domain-containing protein
LUM42_RS07405	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
LUM42_RS07425	COG0308	aminopeptidase N
LUM42_RS07435	COG2902	Dehydrogenase
LUM42_RS07440	COG0167	dihydroorotate dehydrogenase activity
LUM42_RS07450	COG0116	Belongs to the methyltransferase superfamily
LUM42_RS07450	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LUM42_RS07460	COG0488	(ABC) transporter
LUM42_RS07475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LUM42_RS07480	COG1067	ATP-dependent peptidase activity
LUM42_RS07485	COG3120	sequence-specific DNA binding
LUM42_RS07515	COG1450	Type ii and iii secretion system protein
LUM42_RS07685	COG0784	Response regulator, receiver
LUM42_RS07685	COG2205	protein histidine kinase activity
LUM42_RS07700	COG3278	Belongs to the heme-copper respiratory oxidase family
LUM42_RS07715	COG2010	Cytochrome c
LUM42_RS07740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUM42_RS07745	COG0589	response to stress
LUM42_RS07770	COG3842	ATPase activity
LUM42_RS07780	COG1177	transmembrane transport
LUM42_RS07790	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LUM42_RS07795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LUM42_RS07800	COG0004	ammonium transporteR
LUM42_RS07815	COG0437	4 iron, 4 sulfur cluster binding
LUM42_RS07830	COG3381	protein complex oligomerization
LUM42_RS07850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LUM42_RS07865	COG3852	Histidine kinase
LUM42_RS07870	COG2204	response regulator
LUM42_RS07880	COG4662	Binding-protein-dependent transport system inner membrane component
LUM42_RS07885	COG3842	ATPase activity
LUM42_RS07890	COG0746	molybdenum cofactor guanylyltransferase activity
LUM42_RS07895	COG0303	'Molybdopterin
LUM42_RS07905	COG1940	carbohydrate kinase activity
LUM42_RS07910	COG3148	PFAM DTW domain containing protein
LUM42_RS07925	COG0791	NLP P60 protein
LUM42_RS07935	COG3001	Fructosamine kinase
LUM42_RS07945	COG0307	riboflavin synthase, alpha
LUM42_RS07960	COG1793	dna ligase
LUM42_RS07965	COG4667	esterase of the alpha-beta hydrolase superfamily
LUM42_RS07985	COG0848	biopolymer transport protein
LUM42_RS07990	COG0811	peptide transport
LUM42_RS07995	COG0811	peptide transport
LUM42_RS08005	COG3040	lipid binding
LUM42_RS08010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUM42_RS08015	COG0039	L-malate dehydrogenase activity
LUM42_RS08030	COG0395	ABC-type sugar transport system, permease component
LUM42_RS08035	COG3842	ATPase activity
LUM42_RS08040	COG1349	DNA-binding transcription factor activity
LUM42_RS08050	COG2731	YhcH YjgK YiaL family protein
LUM42_RS08070	COG0625	glutathione transferase activity
LUM42_RS08080	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LUM42_RS08090	COG2200	EAL domain
LUM42_RS08095	COG2195	Cleaves the N-terminal amino acid of tripeptides
LUM42_RS08115	COG2814	Major facilitator Superfamily
LUM42_RS08120	COG1566	PFAM secretion protein HlyD family protein
LUM42_RS08140	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LUM42_RS08145	COG0372	Belongs to the citrate synthase family
LUM42_RS08150	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LUM42_RS08160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LUM42_RS08160	COG2169	Transcriptional regulator
LUM42_RS08195	COG1129	ABC transporter
LUM42_RS08205	COG3250	beta-galactosidase activity
LUM42_RS08215	COG2991	Protein conserved in bacteria
LUM42_RS08220	COG0778	Nitroreductase
LUM42_RS08225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LUM42_RS08240	COG4191	Histidine kinase
LUM42_RS08240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUM42_RS08245	COG0471	metal ion transport
LUM42_RS08265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUM42_RS08280	COG3106	COG3106 Predicted ATPase
LUM42_RS08295	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LUM42_RS08300	COG2205	protein histidine kinase activity
LUM42_RS08300	COG0784	Response regulator, receiver
LUM42_RS08310	COG0494	nUDIX hydrolase
LUM42_RS08315	COG0814	amino acid
LUM42_RS08320	COG1760	l-serine dehydratase
LUM42_RS08325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUM42_RS08330	COG1136	(ABC) transporter
LUM42_RS08330	COG0577	efflux transmembrane transporter activity
LUM42_RS08350	COG0720	synthase
LUM42_RS08360	COG0017	Asparaginyl-tRNA synthetase
LUM42_RS08375	COG1448	Aminotransferase
LUM42_RS08390	COG2176	DNA-directed DNA polymerase activity
LUM42_RS08395	COG0840	transmembrane signaling receptor activity
LUM42_RS08400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LUM42_RS08405	COG1846	Transcriptional regulator
LUM42_RS08430	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LUM42_RS08445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUM42_RS08450	COG3108	Peptidase M15
LUM42_RS08455	COG2989	Protein conserved in bacteria
LUM42_RS08480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LUM42_RS08495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LUM42_RS08500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LUM42_RS08530	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LUM42_RS08535	COG3265	gluconokinase activity
LUM42_RS08550	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LUM42_RS08595	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LUM42_RS08610	COG4181	ATPase activity
LUM42_RS08615	COG0534	Mate efflux family protein
LUM42_RS08620	COG0702	epimerase
LUM42_RS08630	COG2814	Major facilitator Superfamily
LUM42_RS08640	COG1061	Type III restriction enzyme res subunit
LUM42_RS08655	COG0642	Histidine kinase
LUM42_RS08660	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LUM42_RS08690	COG0679	Auxin Efflux Carrier
LUM42_RS08705	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LUM42_RS08720	COG3153	acetyltransferase
LUM42_RS08730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LUM42_RS08735	COG3069	C4-dicarboxylate transmembrane transporter activity
LUM42_RS08750	COG1737	Transcriptional regulator
LUM42_RS08765	COG1278	Cold shock
LUM42_RS08775	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LUM42_RS08785	COG0814	amino acid
LUM42_RS08795	COG1131	(ABC) transporter
LUM42_RS08800	COG0842	Transport permease protein
LUM42_RS08810	COG3313	Fe-S protein
LUM42_RS08820	COG4134	Bacterial extracellular solute-binding protein
LUM42_RS08825	COG4135	transport system, permease component
LUM42_RS08830	COG4136	ATPase activity
LUM42_RS08835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LUM42_RS08850	COG0564	pseudouridine synthase activity
LUM42_RS08860	COG0733	neurotransmitter:sodium symporter activity
LUM42_RS08870	COG0626	cystathionine gamma-synthase activity
LUM42_RS08875	COG2818	Glycosylase
LUM42_RS08890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUM42_RS08905	COG1842	Phage shock protein A
LUM42_RS08910	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LUM42_RS08920	COG4168	peptide transport system, permease
LUM42_RS08925	COG4171	peptide transport system, permease
LUM42_RS08935	COG4172	Belongs to the ABC transporter superfamily
LUM42_RS08950	COG1227	inorganic diphosphatase activity
LUM42_RS08970	COG0243	molybdopterin cofactor binding
LUM42_RS08975	COG3005	denitrification pathway
LUM42_RS08980	COG4459	periplasmic nitrate reductase
LUM42_RS08985	COG0390	transport system, permease component
LUM42_RS08990	COG2116	formate transmembrane transporter activity
LUM42_RS09005	COG0583	DNA-binding transcription factor activity
LUM42_RS09010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LUM42_RS09015	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LUM42_RS09020	COG1435	thymidine kinase activity
LUM42_RS09030	COG1801	Protein of unknown function DUF72
LUM42_RS09035	COG4106	trans-aconitate 2-methyltransferase activity
LUM42_RS09040	COG0500	methyltransferase
LUM42_RS09045	COG0189	ligase activity
LUM42_RS09045	COG4067	protein conserved in archaea
LUM42_RS09065	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
LUM42_RS09070	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LUM42_RS09075	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LUM42_RS09080	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LUM42_RS09085	COG0745	RESPONSE REGULATOR receiver
LUM42_RS09090	COG3381	protein complex oligomerization
LUM42_RS09095	COG1609	Transcriptional regulator
LUM42_RS09100	COG3070	regulator of competence-specific genes
LUM42_RS09120	COG0297	glycogen (starch) synthase activity
LUM42_RS09125	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LUM42_RS09135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LUM42_RS09155	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LUM42_RS09160	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LUM42_RS09165	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LUM42_RS09170	COG0542	response to heat
LUM42_RS09175	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LUM42_RS09180	COG1278	Cold shock
LUM42_RS09190	COG2223	nitrite transmembrane transporter activity
LUM42_RS09195	COG1695	Transcriptional regulator
LUM42_RS09205	COG1187	pseudouridine synthase activity
LUM42_RS09210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LUM42_RS09210	COG0140	phosphoribosyl-ATP diphosphatase activity
LUM42_RS09220	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LUM42_RS09225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LUM42_RS09230	COG0131	Imidazoleglycerol-phosphate dehydratase
LUM42_RS09230	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LUM42_RS09235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LUM42_RS09240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LUM42_RS09245	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LUM42_RS09255	COG1757	Na H antiporter
LUM42_RS09260	COG2916	Histone family protein nucleoid-structuring protein H-NS
LUM42_RS09265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUM42_RS09270	COG0482	sulfurtransferase activity
LUM42_RS09275	COG2915	High frequency lysogenization protein hflD homolog
LUM42_RS09280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LUM42_RS09300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LUM42_RS09315	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_RS09325	COG0501	Belongs to the peptidase M48B family
LUM42_RS09335	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LUM42_RS09340	COG2226	methyltransferase
LUM42_RS09350	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LUM42_RS09355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LUM42_RS09365	COG2146	nitrite reductase [NAD(P)H] activity
LUM42_RS09365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LUM42_RS09370	COG1116	anion transmembrane transporter activity
LUM42_RS09375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUM42_RS09380	COG1116	anion transmembrane transporter activity
LUM42_RS09380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUM42_RS09395	COG1648	precorrin-2 dehydrogenase activity
LUM42_RS09395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LUM42_RS09400	COG0243	molybdopterin cofactor binding
LUM42_RS09410	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LUM42_RS09415	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LUM42_RS09420	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LUM42_RS09425	COG0653	protein targeting
LUM42_RS09430	COG2165	general secretion pathway protein
LUM42_RS09440	COG3706	GGDEF domain
LUM42_RS09450	COG4120	Belongs to the binding-protein-dependent transport system permease family
LUM42_RS09460	COG3092	negative regulation of chromosome organization
LUM42_RS09465	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LUM42_RS09470	COG0857	belongs to the CobB CobQ family
LUM42_RS09470	COG0280	phosphate acetyltransferase
LUM42_RS09475	COG3174	membrane
LUM42_RS09480	COG0435	Glutathione S-transferase
LUM42_RS09495	COG0444	Belongs to the ABC transporter superfamily
LUM42_RS09500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LUM42_RS09505	COG0601	transmembrane transport
LUM42_RS09540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUM42_RS09545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUM42_RS09565	COG1216	Glycosyl transferase, family 2
LUM42_RS09570	COG2986	histidine ammonia-lyase
LUM42_RS09595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LUM42_RS09605	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_RS09625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUM42_RS09635	COG2203	Gaf domain
LUM42_RS09635	COG3706	GGDEF domain
LUM42_RS09635	COG4251	negative regulation of phosphorylation
LUM42_RS09635	COG5001	Diguanylate cyclase
LUM42_RS09640	COG1621	beta-fructofuranosidase activity
LUM42_RS09650	COG1263	PTS System
LUM42_RS09650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUM42_RS09660	COG0745	RESPONSE REGULATOR receiver
LUM42_RS09670	COG2207	Transcriptional regulator
LUM42_RS09670	COG3708	Transcriptional regulator
LUM42_RS09675	COG2814	Major facilitator Superfamily
LUM42_RS09680	COG1566	PFAM secretion protein HlyD family protein
LUM42_RS09685	COG1538	Outer membrane efflux protein
LUM42_RS09695	COG0747	negative chemotaxis
LUM42_RS09700	COG0601	transmembrane transport
LUM42_RS09705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LUM42_RS09710	COG4172	Belongs to the ABC transporter superfamily
LUM42_RS09720	COG1741	Belongs to the pirin family
LUM42_RS09725	COG2723	6-phospho-beta-galactosidase activity
LUM42_RS09730	COG1609	Transcriptional regulator
LUM42_RS09740	COG1120	ATPase activity
LUM42_RS09745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUM42_RS09755	COG1629	transport
LUM42_RS09755	COG4774	siderophore transport
LUM42_RS09760	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_RS09765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_RS09770	COG4592	Periplasmic binding protein
LUM42_RS09785	COG3433	isochorismatase activity
LUM42_RS09785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUM42_RS09785	COG2226	methyltransferase
LUM42_RS09790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LUM42_RS09795	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_RS09800	COG1169	isochorismate synthase
LUM42_RS09805	COG1021	2,3-dihydroxybenzoate-AMP ligase
LUM42_RS09825	COG2249	NAD(P)H dehydrogenase (quinone) activity
LUM42_RS09840	COG3275	phosphorelay sensor kinase activity
LUM42_RS09845	COG3279	Response regulator of the LytR AlgR family
LUM42_RS09850	COG2223	nitrite transmembrane transporter activity
LUM42_RS09875	COG1294	oxidase, subunit
LUM42_RS09880	COG1271	oxidase subunit
LUM42_RS09885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUM42_RS09920	COG4566	intracellular signal transduction
LUM42_RS09925	COG2194	sulfuric ester hydrolase activity
LUM42_RS09930	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LUM42_RS09935	COG1368	sulfuric ester hydrolase activity
LUM42_RS09940	COG0513	Belongs to the DEAD box helicase family
LUM42_RS09960	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUM42_RS09965	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUM42_RS09985	COG2207	Transcriptional regulator
LUM42_RS09990	COG1881	PFAM PEBP family protein
LUM42_RS10010	COG2723	6-phospho-beta-galactosidase activity
LUM42_RS10015	COG1263	PTS System
LUM42_RS10015	COG2190	(PTS) system
LUM42_RS10015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUM42_RS10020	COG3711	transcriptional antiterminator
LUM42_RS10025	COG0679	Auxin Efflux Carrier
LUM42_RS10030	COG0583	DNA-binding transcription factor activity
LUM42_RS10040	COG5001	Diguanylate cyclase
LUM42_RS10040	COG5002	protein histidine kinase activity
LUM42_RS10055	COG3126	Type III secretion system lipoprotein chaperone (YscW)
LUM42_RS10060	COG1946	Acyl-CoA thioesterase
LUM42_RS10065	COG1522	sequence-specific DNA binding
LUM42_RS10110	COG2885	chlorophyll binding
LUM42_RS10110	COG3047	cAMP biosynthetic process
LUM42_RS10140	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LUM42_RS10155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUM42_RS10160	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LUM42_RS10180	COG1580	Controls the rotational direction of flagella during chemotaxis
LUM42_RS10190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LUM42_RS10195	COG1360	Flagellar Motor Protein
LUM42_RS10205	COG3015	lipoprotein NlpE involved in copper resistance
LUM42_RS10250	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LUM42_RS10280	COG1256	bacterial-type flagellum assembly
LUM42_RS10280	COG4786	Flagellar basal body rod
LUM42_RS10290	COG1706	bacterial-type flagellum-dependent cell motility
LUM42_RS10295	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LUM42_RS10300	COG4786	Flagellar basal body rod
LUM42_RS10310	COG1749	Flagellar hook protein flgE
LUM42_RS10315	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LUM42_RS10320	COG1558	bacterial-type flagellum-dependent cell motility
LUM42_RS10325	COG1815	bacterial-type flagellum-dependent cell motility
LUM42_RS10345	COG0741	lytic transglycosylase activity
LUM42_RS10345	COG1388	LysM domain
LUM42_RS10350	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LUM42_RS10370	COG0477	Major facilitator Superfamily
LUM42_RS10375	COG2855	membrane
LUM42_RS10395	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LUM42_RS10405	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LUM42_RS10415	COG0436	Aminotransferase
LUM42_RS10420	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LUM42_RS10425	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LUM42_RS10445	COG0616	signal peptide processing
LUM42_RS10450	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_RS10465	COG0587	DNA-directed DNA polymerase activity
LUM42_RS10470	COG0784	Response regulator, receiver
LUM42_RS10470	COG0835	chemotaxis
LUM42_RS10475	COG1940	carbohydrate kinase activity
LUM42_RS10480	COG0469	pyruvate kinase activity
LUM42_RS10485	COG4667	esterase of the alpha-beta hydrolase superfamily
LUM42_RS10500	COG0733	neurotransmitter:sodium symporter activity
LUM42_RS10515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUM42_RS10515	COG1263	PTS System
LUM42_RS10525	COG1263	PTS System
LUM42_RS10525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUM42_RS10525	COG2190	(PTS) system
LUM42_RS10530	COG0084	hydrolase, TatD family'
LUM42_RS10535	COG0470	DNA polymerase III
LUM42_RS10540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LUM42_RS10545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LUM42_RS10550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LUM42_RS10555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LUM42_RS10575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LUM42_RS10580	COG0416	fatty acid biosynthetic process
LUM42_RS10585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LUM42_RS10590	COG1399	metal-binding, possibly nucleic acid-binding protein
LUM42_RS10595	COG0424	maF-like protein
LUM42_RS10600	COG0564	pseudouridine synthase activity
LUM42_RS10605	COG1530	ribonuclease E activity
LUM42_RS10615	COG0659	secondary active sulfate transmembrane transporter activity
LUM42_RS10625	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_RS10625	COG1454	alcohol dehydrogenase
LUM42_RS10630	COG2095	MarC family integral membrane protein
LUM42_RS10635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUM42_RS10640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LUM42_RS10645	COG1757	Na H antiporter
LUM42_RS10655	COG3081	Nucleoid-associated protein
LUM42_RS10660	COG3082	Protein of unknown function (DUF1414)
LUM42_RS10665	COG3083	sulfuric ester hydrolase activity
LUM42_RS10680	COG2814	Major facilitator Superfamily
LUM42_RS10700	COG1448	Aminotransferase
LUM42_RS10710	COG0123	including yeast histone deacetylase and acetoin utilization protein
LUM42_RS10725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LUM42_RS10765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LUM42_RS10770	COG2159	amidohydrolase
LUM42_RS10775	COG0583	DNA-binding transcription factor activity
LUM42_RS10790	COG0667	Aldo Keto reductase
LUM42_RS10795	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LUM42_RS10815	COG3384	dioxygenase
LUM42_RS10825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LUM42_RS10830	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LUM42_RS10850	COG2853	Lipoprotein
LUM42_RS10865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LUM42_RS10870	COG1138	Cytochrome C-type biogenesis protein
LUM42_RS10875	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LUM42_RS10880	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LUM42_RS10885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LUM42_RS10890	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LUM42_RS10895	COG4133	protoheme IX ABC transporter activity
LUM42_RS10905	COG0835	chemotaxis
LUM42_RS10915	COG1192	Involved in chromosome partitioning
LUM42_RS10920	COG2201	protein-glutamate methylesterase activity
LUM42_RS10925	COG2198	Histidine kinase
LUM42_RS10925	COG0643	Histidine kinase
LUM42_RS10925	COG0784	Response regulator, receiver
LUM42_RS10930	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LUM42_RS10960	COG2062	phosphohistidine phosphatase, SixA
LUM42_RS10970	COG3102	Protein conserved in bacteria
LUM42_RS10995	COG1918	ferrous iron import across plasma membrane
LUM42_RS11000	COG2207	Transcriptional regulator
LUM42_RS11005	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LUM42_RS11010	COG1121	(ABC) transporter
LUM42_RS11015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LUM42_RS11030	COG0508	dehydrogenase complex catalyzes the overall conversion of
LUM42_RS11035	COG0567	Dehydrogenase, E1 component
LUM42_RS11045	COG1053	succinate dehydrogenase
LUM42_RS11050	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LUM42_RS11065	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LUM42_RS11075	COG0033	Phosphoglucomutase
LUM42_RS11080	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LUM42_RS11085	COG0596	Alpha beta hydrolase
LUM42_RS11100	COG1346	cytolysis
LUM42_RS11105	COG1380	Effector of murein hydrolase LrgA
LUM42_RS11110	COG0583	DNA-binding transcription factor activity
LUM42_RS11120	COG0735	belongs to the Fur family
LUM42_RS11125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LUM42_RS11130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LUM42_RS11135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LUM42_RS11140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUM42_RS11140	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LUM42_RS11155	COG3101	peptidyl-lysine hydroxylation
LUM42_RS11160	COG2860	membrane
LUM42_RS11165	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LUM42_RS11170	COG2890	protein-(glutamine-N5) methyltransferase activity
LUM42_RS11175	COG2840	Smr protein MutS2
LUM42_RS11190	COG1987	bacterial-type flagellum assembly
LUM42_RS11240	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LUM42_RS11250	COG1677	Flagellar hook-basal body complex protein FliE
LUM42_RS11270	COG1516	flagellar protein fliS
LUM42_RS11280	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LUM42_RS11285	COG1334	flagellar protein FlaG
LUM42_RS11290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUM42_RS11305	COG2837	iron assimilation
LUM42_RS11325	COG0516	GMP reductase activity
LUM42_RS11325	COG0517	IMP dehydrogenase activity
LUM42_RS11340	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LUM42_RS11345	COG1085	galactose-1-phosphate uridylyltransferase
LUM42_RS11350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LUM42_RS11360	COG1393	Belongs to the ArsC family
LUM42_RS11370	COG1876	peptidase activity
LUM42_RS11380	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LUM42_RS11390	COG2716	regulation of RNA biosynthetic process
LUM42_RS11420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LUM42_RS11480	COG4783	chaperone-mediated protein folding
LUM42_RS11485	COG1393	Belongs to the ArsC family
LUM42_RS11505	COG2233	PERMEase
LUM42_RS11510	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LUM42_RS11515	COG0737	Belongs to the 5'-nucleotidase family
LUM42_RS11520	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LUM42_RS11525	COG2912	Transglutaminase-like superfamily
LUM42_RS11535	COG2890	protein-(glutamine-N5) methyltransferase activity
LUM42_RS11540	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LUM42_RS11545	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LUM42_RS11550	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LUM42_RS11555	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LUM42_RS11560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LUM42_RS11565	COG0193	aminoacyl-tRNA hydrolase activity
LUM42_RS11665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUM42_RS11670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUM42_RS11680	COG1705	Flagellar rod assembly protein muramidase FlgJ
LUM42_RS11680	COG3951	Flagellar rod assembly protein muramidase FlgJ
LUM42_RS11685	COG1706	bacterial-type flagellum-dependent cell motility
LUM42_RS11690	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LUM42_RS11700	COG4787	bacterial-type flagellum-dependent cell motility
LUM42_RS11720	COG1815	bacterial-type flagellum-dependent cell motility
LUM42_RS11725	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LUM42_RS11730	COG0784	Response regulator, receiver
LUM42_RS11730	COG0835	chemotaxis
LUM42_RS11740	COG2747	anti-sigma28 factor FlgM
LUM42_RS11780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LUM42_RS11785	COG2608	mercury ion transmembrane transporter activity
LUM42_RS11785	COG2217	Heavy metal translocating P-type atpase
LUM42_RS11820	COG2840	Smr protein MutS2
LUM42_RS11825	COG1187	pseudouridine synthase activity
LUM42_RS11830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LUM42_RS11835	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LUM42_RS11840	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LUM42_RS11845	COG0121	glutamine amidotransferase
LUM42_RS11850	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LUM42_RS11855	COG1960	acyl-CoA dehydrogenase activity
LUM42_RS11865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LUM42_RS11870	COG0328	RNA-DNA hybrid ribonuclease activity
LUM42_RS11875	COG2226	methyltransferase
LUM42_RS11880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUM42_RS11885	COG0741	lytic transglycosylase activity
LUM42_RS11885	COG1388	LysM domain
LUM42_RS11895	COG3021	interspecies interaction between organisms
LUM42_RS11900	COG0347	Belongs to the P(II) protein family
LUM42_RS11910	COG0037	tRNA processing
LUM42_RS11915	COG0825	malonyl-CoA metabolic process
LUM42_RS11920	COG0587	DNA-directed DNA polymerase activity
LUM42_RS11925	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LUM42_RS11940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LUM42_RS11945	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LUM42_RS11950	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LUM42_RS11960	COG0750	zinc metalloprotease
LUM42_RS11965	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LUM42_RS11970	COG0575	Belongs to the CDS family
LUM42_RS11975	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LUM42_RS11980	COG0233	cytoplasmic translational termination
LUM42_RS11990	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LUM42_RS11995	COG0052	Belongs to the universal ribosomal protein uS2 family
LUM42_RS12000	COG0024	Methionine aminopeptidase
LUM42_RS12005	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LUM42_RS12015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LUM42_RS12020	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LUM42_RS12025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LUM42_RS12030	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LUM42_RS12045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LUM42_RS12045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LUM42_RS12050	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LUM42_RS12055	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LUM42_RS12070	COG1073	alpha beta
LUM42_RS12075	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LUM42_RS12080	COG2252	PERMEase
LUM42_RS12085	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LUM42_RS12095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LUM42_RS12105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUM42_RS12110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUM42_RS12115	COG2195	Cleaves the N-terminal amino acid of tripeptides
LUM42_RS12120	COG0189	ligase activity
LUM42_RS12120	COG4067	protein conserved in archaea
LUM42_RS12125	COG0189	ligase activity
LUM42_RS12135	COG0733	neurotransmitter:sodium symporter activity
LUM42_RS12140	COG5001	Diguanylate cyclase
LUM42_RS12140	COG4251	negative regulation of phosphorylation
LUM42_RS12140	COG3706	GGDEF domain
LUM42_RS12140	COG2203	Gaf domain
LUM42_RS12150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LUM42_RS12165	COG1477	protein flavinylation
LUM42_RS12170	COG2871	sodium ion transport
LUM42_RS12175	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LUM42_RS12180	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LUM42_RS12190	COG1805	sodium ion transport
LUM42_RS12195	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LUM42_RS12200	COG0271	Belongs to the BolA IbaG family
LUM42_RS12275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUM42_RS12285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUM42_RS12290	COG0590	tRNA wobble adenosine to inosine editing
LUM42_RS12300	COG0542	response to heat
LUM42_RS12310	COG0564	pseudouridine synthase activity
LUM42_RS12315	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUM42_RS12320	COG0741	lytic transglycosylase activity
LUM42_RS12325	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LUM42_RS12330	COG0077	Prephenate dehydratase
LUM42_RS12330	COG1605	Chorismate mutase
LUM42_RS12335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LUM42_RS12340	COG5001	Diguanylate cyclase
LUM42_RS12345	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LUM42_RS12350	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LUM42_RS12360	COG0488	(ABC) transporter
LUM42_RS12370	COG0287	Prephenate dehydrogenase
LUM42_RS12370	COG1605	Chorismate mutase
LUM42_RS12375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LUM42_RS12380	COG3275	phosphorelay sensor kinase activity
LUM42_RS12385	COG3279	Response regulator of the LytR AlgR family
LUM42_RS12395	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LUM42_RS12400	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LUM42_RS12415	COG1966	Carbon starvation protein
LUM42_RS12420	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LUM42_RS12425	COG1047	Peptidyl-prolyl cis-trans
LUM42_RS12430	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LUM42_RS12435	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LUM42_RS12440	COG0196	riboflavin kinase activity
LUM42_RS12445	COG0728	peptidoglycan biosynthetic process
LUM42_RS12450	COG0268	Binds directly to 16S ribosomal RNA
LUM42_RS12455	COG0640	Transcriptional regulator
LUM42_RS12460	COG0583	DNA-binding transcription factor activity
LUM42_RS12465	COG1283	sodium-dependent phosphate transmembrane transporter activity
LUM42_RS12470	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LUM42_RS12480	COG0730	response to heat
LUM42_RS12490	COG0494	nUDIX hydrolase
LUM42_RS12505	COG0667	Aldo Keto reductase
LUM42_RS12515	COG2204	response regulator
LUM42_RS12520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LUM42_RS12535	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LUM42_RS12540	COG0513	Belongs to the DEAD box helicase family
LUM42_RS12630	COG1279	arginine transmembrane transporter activity
LUM42_RS12655	COG4533	DNA binding
LUM42_RS12675	COG2003	Belongs to the UPF0758 family
LUM42_RS12700	COG0714	Associated with various cellular activities
LUM42_RS12720	COG0629	single-stranded DNA binding
LUM42_RS12735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LUM42_RS12755	COG3706	GGDEF domain
LUM42_RS12790	COG0681	Belongs to the peptidase S26 family
LUM42_RS12900	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LUM42_RS12910	COG0732	type I restriction modification DNA specificity domain
LUM42_RS12915	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LUM42_RS12935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LUM42_RS12975	COG0557	exoribonuclease II activity
LUM42_RS12980	COG1278	Cold shock
LUM42_RS12995	COG3550	peptidyl-serine autophosphorylation
LUM42_RS13000	COG3620	sequence-specific DNA binding
LUM42_RS13020	COG3153	acetyltransferase
LUM42_RS13025	COG3154	lipid carrier protein
LUM42_RS13035	COG0826	peptidase U32
LUM42_RS13040	COG0826	peptidase U32
LUM42_RS13045	COG0534	Mate efflux family protein
LUM42_RS13065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LUM42_RS13075	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LUM42_RS13080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LUM42_RS13085	COG0195	Participates in both transcription termination and antitermination
LUM42_RS13090	COG0779	Required for maturation of 30S ribosomal subunits
LUM42_RS13105	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LUM42_RS13110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LUM42_RS13115	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LUM42_RS13120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LUM42_RS13125	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LUM42_RS13130	COG1534	Rna-binding protein
LUM42_RS13135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LUM42_RS13140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LUM42_RS13145	COG2027	D-alanyl-D-alanine carboxypeptidase
LUM42_RS13150	COG2239	Acts as a magnesium transporter
LUM42_RS13160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LUM42_RS13165	COG0739	heme binding
LUM42_RS13180	COG0316	Belongs to the HesB IscA family
LUM42_RS13185	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LUM42_RS13190	COG0628	permease
LUM42_RS13195	COG2813	Specifically methylates the guanine in position
LUM42_RS13200	COG0784	Response regulator, receiver
LUM42_RS13200	COG2205	protein histidine kinase activity
LUM42_RS13205	COG0747	negative chemotaxis
LUM42_RS13215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LUM42_RS13220	COG0444	Belongs to the ABC transporter superfamily
LUM42_RS13225	COG4608	Belongs to the ABC transporter superfamily
LUM42_RS13235	COG2971	BadF BadG BcrA BcrD
LUM42_RS13250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LUM42_RS13255	COG3842	ATPase activity
LUM42_RS13265	COG1840	ABC-type Fe3 transport system, periplasmic component
LUM42_RS13270	COG0004	ammonium transporteR
LUM42_RS13275	COG0347	Belongs to the P(II) protein family
LUM42_RS13280	COG3112	Uncharacterised protein family (UPF0231)
LUM42_RS13285	COG1049	propionate catabolic process, 2-methylcitrate cycle
LUM42_RS13290	COG1752	Esterase of the alpha-beta hydrolase superfamily
LUM42_RS13295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LUM42_RS13300	COG1643	Atp-dependent helicase
LUM42_RS13305	COG1489	DNA binding
LUM42_RS13310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LUM42_RS13315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LUM42_RS13325	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LUM42_RS13330	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LUM42_RS13335	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LUM42_RS13340	COG0842	Transport permease protein
LUM42_RS13345	COG1131	(ABC) transporter
LUM42_RS13350	COG0288	reversible hydration of carbon dioxide
LUM42_RS13365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LUM42_RS13370	COG0508	dehydrogenase complex catalyzes the overall conversion of
LUM42_RS13375	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LUM42_RS13380	COG2186	Transcriptional regulator
LUM42_RS13385	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LUM42_RS13390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LUM42_RS13395	COG4974	Belongs to the 'phage' integrase family
LUM42_RS13420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LUM42_RS13425	COG1459	type II secretion system
LUM42_RS13435	COG0237	dephospho-CoA kinase activity
LUM42_RS13440	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
LUM42_RS13460	COG3150	esterase
LUM42_RS13470	COG3151	Protein conserved in bacteria
LUM42_RS13475	COG0494	nUDIX hydrolase
LUM42_RS13480	COG1538	Outer membrane efflux protein
LUM42_RS13485	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LUM42_RS13485	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LUM42_RS13490	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LUM42_RS13500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LUM42_RS13505	COG3025	triphosphatase activity
LUM42_RS13510	COG1392	Phosphate transport regulator
LUM42_RS13515	COG0306	phosphate transporter
LUM42_RS13520	COG4991	sh3 domain protein
LUM42_RS13530	COG3409	Peptidoglycan-binding domain 1 protein
LUM42_RS13530	COG3267	Type II secretory pathway component ExeA
LUM42_RS13535	COG0617	tRNA 3'-terminal CCA addition
LUM42_RS13540	COG0148	phosphopyruvate hydratase activity
LUM42_RS13545	COG0504	CTP synthase activity
LUM42_RS13550	COG3956	TIGRFAM MazG family protein
LUM42_RS13555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LUM42_RS13560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LUM42_RS13575	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LUM42_RS13580	COG1381	Involved in DNA repair and RecF pathway recombination
LUM42_RS13585	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LUM42_RS13600	COG0481	GTPase activity
LUM42_RS13605	COG3086	response to oxidative stress
LUM42_RS13620	COG1595	DNA-templated transcription, initiation
LUM42_RS13625	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LUM42_RS13635	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LUM42_RS13655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUM42_RS13660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUM42_RS13665	COG3079	Belongs to the UPF0149 family
LUM42_RS13670	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LUM42_RS13680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LUM42_RS13690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LUM42_RS13695	COG0440	acetolactate synthase activity
LUM42_RS13700	COG0028	Belongs to the TPP enzyme family
LUM42_RS13705	COG1022	Amp-dependent synthetase and ligase
LUM42_RS13710	COG0583	DNA-binding transcription factor activity
LUM42_RS13735	COG0473	3-isopropylmalate dehydrogenase activity
LUM42_RS13740	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LUM42_RS13745	COG0066	3-isopropylmalate dehydratase activity
LUM42_RS13790	COG3437	response regulator, receiver
LUM42_RS13815	COG3706	GGDEF domain
LUM42_RS13825	COG0795	lipopolysaccharide-transporting ATPase activity
LUM42_RS13830	COG0795	lipopolysaccharide-transporting ATPase activity
LUM42_RS13835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LUM42_RS13845	COG0525	valine-tRNA ligase activity
LUM42_RS13850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LUM42_RS13855	COG0564	pseudouridine synthase activity
LUM42_RS13870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LUM42_RS13875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LUM42_RS13880	COG0540	Belongs to the ATCase OTCase family
LUM42_RS13885	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LUM42_RS13890	COG0251	oxidation-reduction process
LUM42_RS13895	COG0204	Acyl-transferase
LUM42_RS13905	COG5007	Belongs to the BolA IbaG family
LUM42_RS13910	COG3113	response to antibiotic
LUM42_RS13915	COG2854	intermembrane phospholipid transfer
LUM42_RS13920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LUM42_RS13925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LUM42_RS13930	COG1127	ABC transporter
LUM42_RS13940	COG0517	IMP dehydrogenase activity
LUM42_RS13940	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LUM42_RS13945	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LUM42_RS13955	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LUM42_RS13960	COG1137	ATPase activity
LUM42_RS13970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LUM42_RS13975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUM42_RS13980	COG1660	Displays ATPase and GTPase activities
LUM42_RS13985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUM42_RS13990	COG2239	Acts as a magnesium transporter
LUM42_RS13995	COG0312	modulator of DNA gyrase
LUM42_RS14000	COG3028	Belongs to the UPF0307 family
LUM42_RS14005	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LUM42_RS14010	COG1178	ABC-type Fe3 transport system permease component
LUM42_RS14015	COG4143	(ABC) transporter
LUM42_RS14020	COG0163	prenyltransferase activity
LUM42_RS14025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LUM42_RS14030	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LUM42_RS14035	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LUM42_RS14045	COG2105	PFAM AIG2 family protein
LUM42_RS14055	COG0729	surface antigen
LUM42_RS14060	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LUM42_RS14065	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LUM42_RS14080	COG0577	efflux transmembrane transporter activity
LUM42_RS14080	COG1136	(ABC) transporter
LUM42_RS14100	COG0529	Catalyzes the synthesis of activated sulfate
LUM42_RS14105	COG0471	metal ion transport
LUM42_RS14105	COG3273	potassium ion transport
LUM42_RS14110	COG2895	sulfate adenylyltransferase (ATP) activity
LUM42_RS14115	COG0175	sulfate reduction
LUM42_RS14120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LUM42_RS14120	COG1648	precorrin-2 dehydrogenase activity
LUM42_RS14125	COG0737	Belongs to the 5'-nucleotidase family
LUM42_RS14135	COG0513	Belongs to the DEAD box helicase family
LUM42_RS14140	COG2153	protein acetylation
LUM42_RS14150	COG3061	Opacity-associated protein A
LUM42_RS14155	COG0545	Peptidyl-prolyl cis-trans isomerase
LUM42_RS14165	COG0203	ribosomal protein L17
LUM42_RS14170	COG0202	RNA polymerase activity
LUM42_RS14175	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LUM42_RS14180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LUM42_RS14185	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LUM42_RS14190	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LUM42_RS14195	COG0201	protein transport
LUM42_RS14200	COG0200	Binds to the 23S rRNA
LUM42_RS14205	COG1841	ribosomal large subunit assembly
LUM42_RS14215	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LUM42_RS14225	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LUM42_RS14230	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LUM42_RS14235	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LUM42_RS14240	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LUM42_RS14245	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LUM42_RS14250	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LUM42_RS14255	COG0255	Belongs to the universal ribosomal protein uL29 family
LUM42_RS14260	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LUM42_RS14265	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LUM42_RS14270	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LUM42_RS14275	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LUM42_RS14280	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LUM42_RS14285	COG0089	rRNA binding
LUM42_RS14290	COG0088	Forms part of the polypeptide exit tunnel
LUM42_RS14295	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LUM42_RS14300	COG0051	transcription antitermination factor activity, RNA binding
LUM42_RS14305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LUM42_RS14310	COG0557	exoribonuclease II activity
LUM42_RS14315	COG3083	sulfuric ester hydrolase activity
LUM42_RS14320	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LUM42_RS14325	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LUM42_RS14335	COG1047	Peptidyl-prolyl cis-trans
LUM42_RS14340	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LUM42_RS14350	COG2249	NAD(P)H dehydrogenase (quinone) activity
LUM42_RS14355	COG0488	(ABC) transporter
LUM42_RS14365	COG0429	hydrolase of the alpha beta-hydrolase fold
LUM42_RS14375	COG3954	Phosphoribulokinase
LUM42_RS14390	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_RS14400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LUM42_RS14405	COG0512	Glutamine amidotransferase of anthranilate synthase
LUM42_RS14415	COG0180	Tryptophanyl-tRNA synthetase
LUM42_RS14425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LUM42_RS14430	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LUM42_RS14440	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LUM42_RS14475	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LUM42_RS14485	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LUM42_RS14485	COG0678	peroxiredoxin activity
LUM42_RS14495	COG0165	Argininosuccinate lyase
LUM42_RS14495	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LUM42_RS14505	COG0137	argininosuccinate synthase activity
LUM42_RS14510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LUM42_RS14515	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LUM42_RS14520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LUM42_RS14525	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LUM42_RS14535	COG1045	serine acetyltransferase
LUM42_RS14545	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LUM42_RS14550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LUM42_RS14555	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LUM42_RS14560	COG1053	succinate dehydrogenase
LUM42_RS14565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LUM42_RS14570	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LUM42_RS14580	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LUM42_RS14585	COG1509	lysine 2,3-aminomutase activity
LUM42_RS14590	COG1285	pathogenesis
LUM42_RS14600	COG1119	ATPase activity
LUM42_RS14605	COG0459	protein refolding
LUM42_RS14635	COG0149	triose-phosphate isomerase activity
LUM42_RS14640	COG0534	Mate efflux family protein
LUM42_RS14645	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LUM42_RS14650	COG1575	Belongs to the MenA family. Type 1 subfamily
LUM42_RS14655	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LUM42_RS14660	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LUM42_RS14670	COG1609	Transcriptional regulator
LUM42_RS14675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LUM42_RS14685	COG0281	malic enzyme
LUM42_RS14690	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LUM42_RS14695	COG0626	cystathionine gamma-synthase activity
LUM42_RS14700	COG0460	homoserine dehydrogenase
LUM42_RS14700	COG0527	aspartate kinase activity
LUM42_RS14705	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LUM42_RS14710	COG3074	FtsZ-dependent cytokinesis
LUM42_RS14715	COG1494	fructose-1,6-bisphosphatase
LUM42_RS14720	COG0205	6-phosphofructokinase activity
LUM42_RS14725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LUM42_RS14735	COG0745	RESPONSE REGULATOR receiver
LUM42_RS14740	COG2205	protein histidine kinase activity
LUM42_RS14745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LUM42_RS14750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LUM42_RS14765	COG1027	Aspartate ammonia-lyase
LUM42_RS14770	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LUM42_RS14775	COG1288	antiporter activity
LUM42_RS14790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LUM42_RS14795	COG0540	Belongs to the ATCase OTCase family
LUM42_RS14800	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LUM42_RS14810	COG4232	protein-disulfide reductase activity
LUM42_RS14835	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LUM42_RS14840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LUM42_RS14845	COG0194	GDP metabolic process
LUM42_RS14850	COG1758	RNA polymerase activity
LUM42_RS14855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LUM42_RS14865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LUM42_RS14870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LUM42_RS14875	COG2233	PERMEase
LUM42_RS14890	COG0800	Aldolase
LUM42_RS14895	COG2610	gluconate transmembrane transporter activity
LUM42_RS14900	COG3265	gluconokinase activity
LUM42_RS14905	COG0129	dihydroxy-acid dehydratase activity
LUM42_RS14910	COG1609	Transcriptional regulator
LUM42_RS14915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LUM42_RS14925	COG2183	response to ionizing radiation
LUM42_RS14935	COG0596	Alpha beta hydrolase
LUM42_RS14940	COG1040	competence protein
LUM42_RS14950	COG0494	nUDIX hydrolase
LUM42_RS14955	COG1218	3'(2'),5'-bisphosphate nucleotidase
LUM42_RS14965	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LUM42_RS14970	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LUM42_RS14975	COG3156	type II secretion system protein K
LUM42_RS14980	COG4795	General secretion pathway protein
LUM42_RS14985	COG2165	general secretion pathway protein
LUM42_RS14990	COG2165	general secretion pathway protein
LUM42_RS14995	COG2165	general secretion pathway protein
LUM42_RS15000	COG1459	type II secretion system
LUM42_RS15005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LUM42_RS15015	COG3031	protein transport across the cell outer membrane
LUM42_RS15020	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LUM42_RS15030	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LUM42_RS15035	COG2982	Protein involved in outer membrane biogenesis
LUM42_RS15040	COG0456	acetyltransferase
LUM42_RS15045	COG1490	D-aminoacyl-tRNA deacylase activity
LUM42_RS15065	COG1217	gtp-binding protein TYPA
LUM42_RS15070	COG0174	glutamine synthetase
LUM42_RS15080	COG3852	Histidine kinase
LUM42_RS15085	COG2204	response regulator
LUM42_RS15090	COG3300	MHYT domain
LUM42_RS15090	COG5001	Diguanylate cyclase
LUM42_RS15095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LUM42_RS15145	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LUM42_RS15155	COG4206	TonB-dependent receptor
LUM42_RS15160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LUM42_RS15175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LUM42_RS15180	COG0534	Mate efflux family protein
LUM42_RS15190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LUM42_RS15195	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LUM42_RS15200	COG2937	Belongs to the GPAT DAPAT family
LUM42_RS15205	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LUM42_RS15210	COG3161	chorismate lyase activity
LUM42_RS15215	COG1580	Controls the rotational direction of flagella during chemotaxis
LUM42_RS15220	COG0705	Rhomboid family
LUM42_RS15225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LUM42_RS15230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LUM42_RS15235	COG2177	Part of the ABC transporter FtsEX involved in
LUM42_RS15240	COG2884	Cell division ATP-binding protein ftsE
LUM42_RS15245	COG0552	protein localization to endoplasmic reticulum
LUM42_RS15250	COG0742	ribosomal rna small subunit methyltransferase
LUM42_RS15260	COG2095	MarC family integral membrane protein
LUM42_RS15290	COG0783	Belongs to the Dps family
LUM42_RS15305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LUM42_RS15310	COG0640	Transcriptional regulator
LUM42_RS15315	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LUM42_RS15320	COG1280	lysine exporter protein (LysE YggA)
LUM42_RS15325	COG2267	carboxylic ester hydrolase activity
LUM42_RS15330	COG0561	phosphatase activity
LUM42_RS15345	COG3148	PFAM DTW domain containing protein
LUM42_RS15350	COG2199	diguanylate cyclase activity
LUM42_RS15350	COG2200	EAL domain
LUM42_RS15350	COG3287	FIST C domain
LUM42_RS15355	COG1011	Hydrolase
LUM42_RS15360	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LUM42_RS15370	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LUM42_RS15375	COG0019	diaminopimelate decarboxylase activity
LUM42_RS15385	COG1965	Belongs to the frataxin family
LUM42_RS15390	COG3072	Adenylate cyclase
LUM42_RS15405	COG2959	enzyme of heme biosynthesis
LUM42_RS15410	COG3071	HemY protein
LUM42_RS15415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LUM42_RS15445	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LUM42_RS15445	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LUM42_RS15460	COG0084	hydrolase, TatD family'
LUM42_RS15465	COG0805	protein transport
LUM42_RS15470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LUM42_RS15475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LUM42_RS15485	COG3165	ubiquinone biosynthetic process from chorismate
LUM42_RS15490	COG2226	methyltransferase
LUM42_RS15495	COG1322	Protein conserved in bacteria
LUM42_RS15520	COG2160	L-arabinose isomerase activity
LUM42_RS15530	COG1069	ribulokinase activity
LUM42_RS15535	COG1879	ABC-type sugar transport system periplasmic component
LUM42_RS15540	COG1129	ABC transporter
LUM42_RS15545	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUM42_RS15550	COG1879	ABC-type sugar transport system periplasmic component
LUM42_RS15555	COG1129	ABC transporter
LUM42_RS15560	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUM42_RS15565	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUM42_RS15570	COG2081	HI0933 family
LUM42_RS15580	COG1528	Iron-storage protein
LUM42_RS15585	COG0589	response to stress
LUM42_RS15605	COG5001	Diguanylate cyclase
LUM42_RS15605	COG5002	protein histidine kinase activity
LUM42_RS15610	COG1522	sequence-specific DNA binding
LUM42_RS15630	COG0006	proline dipeptidase activity
LUM42_RS15630	COG0006	proline dipeptidase activity
LUM42_RS15635	COG1309	transcriptional regulator
LUM42_RS15640	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_RS15645	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LUM42_RS15660	COG4175	Glycine betaine
LUM42_RS15665	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LUM42_RS15670	COG2022	thiamine diphosphate biosynthetic process
LUM42_RS15680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LUM42_RS15690	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LUM42_RS15695	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LUM42_RS15700	COG2132	Multicopper oxidase
LUM42_RS15775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LUM42_RS15780	COG1739	Uncharacterized protein family UPF0029
LUM42_RS15790	COG0183	Belongs to the thiolase family
LUM42_RS15795	COG0583	DNA-binding transcription factor activity
LUM42_RS15800	COG2814	Major facilitator Superfamily
LUM42_RS15810	COG0765	amino acid transport
LUM42_RS15820	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LUM42_RS15825	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LUM42_RS15830	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LUM42_RS15835	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LUM42_RS15840	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LUM42_RS15845	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LUM42_RS15860	COG3312	ion transport
LUM42_RS15865	COG1475	DNA binding
LUM42_RS15870	COG1192	Involved in chromosome partitioning
LUM42_RS15875	COG0357	Ribosomal RNA small subunit methyltransferase G
LUM42_RS15880	COG0445	tRNA wobble uridine modification
LUM42_RS15885	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LUM42_RS15895	COG0706	membrane insertase activity
LUM42_RS15910	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LUM42_RS15915	COG1126	abc transporter atp-binding protein
LUM42_RS15980	COG1660	Displays ATPase and GTPase activities
LUM42_RS16020	COG0616	signal peptide processing
LUM42_RS16125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LUM42_RS16190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LUM42_RS16250	COG3041	Addiction module toxin RelE StbE family
LUM42_RS16255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LUM42_RS16310	COG1192	Involved in chromosome partitioning
LUM42_RS16395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LUM42_RS16445	COG3328	transposase activity
LUM42_RS16495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LUM42_RS16520	COG5001	Diguanylate cyclase
LUM42_RS16555	COG0714	Associated with various cellular activities
LUM42_RS16565	COG0629	single-stranded DNA binding
LUM42_RS16610	COG0633	Ferredoxin
LUM42_RS16835	COG1396	sequence-specific DNA binding
LUM42_RS16875	COG3173	Aminoglycoside phosphotransferase
LUM42_RS16890	COG4644	lycopene metabolic process
LUM42_RS16980	COG4974	Belongs to the 'phage' integrase family
LUM42_RS17070	COG2909	trisaccharide binding
LUM42_RS17080	COG0109	protoheme IX farnesyltransferase activity
LUM42_RS17085	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LUM42_RS17090	COG1845	cytochrome c oxidase, subunit III
LUM42_RS17095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LUM42_RS17100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LUM42_RS17115	COG2084	Dehydrogenase
LUM42_RS17130	COG0217	transcriptional regulatory protein
LUM42_RS17160	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LUM42_RS17165	COG1444	tRNA N-acetyltransferase activity
LUM42_RS17180	COG2198	Histidine kinase
LUM42_RS17180	COG0643	Histidine kinase
LUM42_RS17185	COG0835	chemotaxis
LUM42_RS17190	COG0835	chemotaxis
LUM42_RS17195	COG0840	transmembrane signaling receptor activity
LUM42_RS17200	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LUM42_RS17205	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
LUM42_RS17210	COG2201	protein-glutamate methylesterase activity
LUM42_RS17225	COG0745	RESPONSE REGULATOR receiver
LUM42_RS17245	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUM42_RS17280	COG0840	transmembrane signaling receptor activity
LUM42_RS17300	COG0513	Belongs to the DEAD box helicase family
LUM42_RS17310	COG0583	DNA-binding transcription factor activity
LUM42_RS17315	COG2226	methyltransferase
LUM42_RS17335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUM42_RS17355	COG0724	RNA recognition motif
LUM42_RS17360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LUM42_RS17365	COG1522	sequence-specific DNA binding
LUM42_RS17370	COG2610	gluconate transmembrane transporter activity
LUM42_RS17375	COG3622	Belongs to the hyi family
LUM42_RS17380	COG0235	Class ii aldolase
LUM42_RS17385	COG3395	kinase activity
LUM42_RS17390	COG2084	Dehydrogenase
LUM42_RS17395	COG1349	DNA-binding transcription factor activity
LUM42_RS17410	COG0583	DNA-binding transcription factor activity
LUM42_RS17415	COG2910	NAD(P)H-binding
LUM42_RS17430	COG1335	isochorismatase
LUM42_RS17435	COG1609	Transcriptional regulator
LUM42_RS17435	COG2207	Transcriptional regulator
LUM42_RS17450	COG2329	Antibiotic biosynthesis monooxygenase
LUM42_RS17455	COG3304	Inner membrane component domain
LUM42_RS17465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUM42_RS17470	COG3706	GGDEF domain
LUM42_RS17485	COG0583	DNA-binding transcription factor activity
LUM42_RS17490	COG4221	oxidoreductase activity
LUM42_RS17495	COG0583	DNA-binding transcription factor activity
LUM42_RS17500	COG1486	melibiose metabolic process
LUM42_RS17570	COG2176	DNA-directed DNA polymerase activity
LUM42_RS17585	COG0443	Heat shock 70 kDa protein
LUM42_RS17590	COG0095	Lipoate-protein ligase
LUM42_RS17595	COG0243	molybdopterin cofactor binding
LUM42_RS17600	COG0437	4 iron, 4 sulfur cluster binding
LUM42_RS17605	COG3302	dmso reductase anchor subunit
LUM42_RS17615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LUM42_RS17615	COG2221	Nitrite and sulphite reductase 4Fe-4S
LUM42_RS17640	COG2376	Dihydroxyacetone kinase
LUM42_RS17645	COG1461	Dihydroxyacetone kinase
LUM42_RS17655	COG3284	Transcriptional regulator
LUM42_RS17665	COG3722	fumarate hydratase activity
LUM42_RS17670	COG0246	Mannitol dehydrogenase
LUM42_RS17675	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUM42_RS17675	COG2213	PTS system mannitol-specific
LUM42_RS17680	COG0739	heme binding
LUM42_RS17695	COG0363	glucosamine-6-phosphate deaminase activity
LUM42_RS17725	COG0402	S-adenosylhomocysteine deaminase activity
LUM42_RS17730	COG2259	Doxx family
LUM42_RS17740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LUM42_RS17750	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LUM42_RS17755	COG1301	dicarboxylic acid transport
LUM42_RS17760	COG1917	Cupin 2, conserved barrel domain protein
LUM42_RS17760	COG2169	Transcriptional regulator
LUM42_RS17790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUM42_RS17800	COG0583	DNA-binding transcription factor activity
LUM42_RS17805	COG1342	Belongs to the UPF0251 family
LUM42_RS17815	COG0583	DNA-binding transcription factor activity
LUM42_RS17820	COG3384	dioxygenase
LUM42_RS17835	COG4774	siderophore transport
LUM42_RS17840	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LUM42_RS17845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_RS17850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_RS17855	COG1120	ATPase activity
LUM42_RS17865	COG0583	DNA-binding transcription factor activity
LUM42_RS17870	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_RS17885	COG0519	Catalyzes the synthesis of GMP from XMP
LUM42_RS17910	COG3152	Membrane
LUM42_RS17930	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LUM42_RS17945	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LUM42_RS17960	COG1620	l-lactate permease
LUM42_RS17965	COG0583	DNA-binding transcription factor activity
LUM42_RS17970	COG4172	Belongs to the ABC transporter superfamily
LUM42_RS17980	COG1067	ATP-dependent peptidase activity
LUM42_RS17990	COG2211	Major facilitator Superfamily
LUM42_RS17995	COG0668	transmembrane transport
LUM42_RS18000	COG0569	domain protein
LUM42_RS18005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LUM42_RS18015	COG3123	guanosine phosphorylase activity
LUM42_RS18025	COG2814	Major facilitator Superfamily
LUM42_RS18145	COG2205	protein histidine kinase activity
LUM42_RS18150	COG0745	RESPONSE REGULATOR receiver
LUM42_RS18155	COG1741	Belongs to the pirin family
LUM42_RS18215	COG3706	GGDEF domain
LUM42_RS18225	COG1846	Transcriptional regulator
LUM42_RS18230	COG2315	Protein conserved in bacteria
LUM42_RS18235	COG0784	Response regulator, receiver
LUM42_RS18235	COG0835	chemotaxis
LUM42_RS18240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LUM42_RS18265	COG1215	transferase activity, transferring glycosyl groups
LUM42_RS18280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LUM42_RS18280	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LUM42_RS18285	COG0367	asparagine synthase
LUM42_RS18300	COG0251	oxidation-reduction process
LUM42_RS18320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LUM42_RS18335	COG2962	Rard protein
LUM42_RS18340	COG1522	sequence-specific DNA binding
LUM42_RS18345	COG2197	response regulator
LUM42_RS18350	COG0393	Putative heavy-metal-binding
LUM42_RS18355	COG0823	Involved in the tonB-independent uptake of proteins
LUM42_RS18360	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LUM42_RS18365	COG0534	Mate efflux family protein
LUM42_RS18375	COG1653	transport
LUM42_RS18380	COG3842	ATPase activity
LUM42_RS18385	COG0395	ABC-type sugar transport system, permease component
LUM42_RS18390	COG1175	transmembrane transport
LUM42_RS18405	COG0840	transmembrane signaling receptor activity
LUM42_RS18415	COG0800	Aldolase
LUM42_RS18420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUM42_RS18430	COG0235	Class ii aldolase
LUM42_RS18435	COG3254	rhamnose metabolic process
LUM42_RS18440	COG4806	L-rhamnose isomerase
LUM42_RS18445	COG1070	Carbohydrate kinase
LUM42_RS18450	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LUM42_RS18480	COG1917	Cupin 2, conserved barrel domain protein
LUM42_RS18490	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_RS18500	COG0517	IMP dehydrogenase activity
LUM42_RS18520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUM42_RS18530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUM42_RS18570	COG3842	ATPase activity
LUM42_RS18580	COG1175	transmembrane transport
LUM42_RS18585	COG3833	ABC-type maltose transport systems, permease component
LUM42_RS18610	COG1349	DNA-binding transcription factor activity
LUM42_RS18630	COG2354	Protein conserved in bacteria
LUM42_RS18635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LUM42_RS18640	COG0418	dihydroorotase activity
LUM42_RS18645	COG0633	Ferredoxin
LUM42_RS18645	COG3217	Mosc domain protein beta barrel domain protein
LUM42_RS18675	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LUM42_RS18680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_RS18690	COG0848	biopolymer transport protein
LUM42_RS18695	COG0811	peptide transport
LUM42_RS18700	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LUM42_RS18710	COG3721	Heme iron utilization protein
LUM42_RS18715	COG0748	coenzyme F420 binding
LUM42_RS18725	COG0531	amino acid
LUM42_RS18730	COG1522	sequence-specific DNA binding
LUM42_RS18750	COG1151	hydroxylamine reductase activity
LUM42_RS18755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LUM42_RS18760	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LUM42_RS18785	COG0784	Response regulator, receiver
LUM42_RS18785	COG2205	protein histidine kinase activity
LUM42_RS18785	COG5002	protein histidine kinase activity
LUM42_RS18805	COG1765	OsmC-like protein
LUM42_RS18815	COG0110	maltose O-acetyltransferase activity
LUM42_RS18845	COG3121	Chaperone
LUM42_RS18850	COG0579	oxidoreductase
LUM42_RS18870	COG0583	DNA-binding transcription factor activity
LUM42_RS18875	COG0798	PFAM Bile acid sodium symporter
LUM42_RS18880	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LUM42_RS18890	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LUM42_RS18940	COG0513	Belongs to the DEAD box helicase family
LUM42_RS18955	COG0840	transmembrane signaling receptor activity
LUM42_RS18975	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LUM42_RS18980	COG1811	Na channel or pump
LUM42_RS19000	COG2985	domain, Protein
LUM42_RS19010	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LUM42_RS19055	COG3122	Protein conserved in bacteria
LUM42_RS19060	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LUM42_RS19070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LUM42_RS19075	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LUM42_RS19075	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LUM42_RS19080	COG0509	glycine decarboxylation via glycine cleavage system
LUM42_RS19085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LUM42_RS19095	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LUM42_RS19110	COG5001	Diguanylate cyclase
LUM42_RS19110	COG3300	MHYT domain
LUM42_RS19115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUM42_RS19155	COG0484	heat shock protein binding
LUM42_RS19165	COG5001	Diguanylate cyclase
LUM42_RS19165	COG1716	ATPase activity
LUM42_RS19170	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LUM42_RS19180	COG4181	ATPase activity
LUM42_RS19185	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LUM42_RS19195	COG1984	allophanate hydrolase subunit 2
LUM42_RS19205	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LUM42_RS19210	COG3447	MASE1 domain protein
LUM42_RS19210	COG5002	protein histidine kinase activity
LUM42_RS19210	COG5001	Diguanylate cyclase
LUM42_RS19220	COG0840	transmembrane signaling receptor activity
LUM42_RS19225	COG0814	amino acid
LUM42_RS19230	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LUM42_RS19235	COG0513	Belongs to the DEAD box helicase family
LUM42_RS19240	COG1309	transcriptional regulator
LUM42_RS19250	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LUM42_RS19265	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LUM42_RS19295	COG0840	transmembrane signaling receptor activity
LUM42_RS19310	COG0583	DNA-binding transcription factor activity
LUM42_RS19315	COG0697	spore germination
LUM42_RS19340	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LUM42_RS19355	COG0406	alpha-ribazole phosphatase activity
LUM42_RS19360	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LUM42_RS19365	COG1454	alcohol dehydrogenase
LUM42_RS19370	COG1609	Transcriptional regulator
LUM42_RS19370	COG2207	Transcriptional regulator
LUM42_RS19380	COG3634	alkyl hydroperoxide reductase activity
LUM42_RS19385	COG0450	alkyl hydroperoxide reductase
LUM42_RS19400	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LUM42_RS19405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LUM42_RS19410	COG1960	acyl-CoA dehydrogenase activity
LUM42_RS19420	COG0183	Belongs to the thiolase family
LUM42_RS19430	COG1960	acyl-CoA dehydrogenase activity
LUM42_RS19435	COG1024	Enoyl-CoA hydratase
LUM42_RS19440	COG1024	Enoyl-CoA hydratase
LUM42_RS19450	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_RS19460	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_RS19470	COG0653	protein targeting
LUM42_RS19485	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LUM42_RS19505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LUM42_RS19505	COG0512	Glutamine amidotransferase of anthranilate synthase
LUM42_RS19510	COG1454	alcohol dehydrogenase
LUM42_RS19515	COG1464	Belongs to the NlpA lipoprotein family
LUM42_RS19535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LUM42_RS19540	COG0573	inorganic phosphate transmembrane transporter activity
LUM42_RS19550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LUM42_RS19555	COG0625	glutathione transferase activity
LUM42_RS19615	COG2721	sulfolactate sulfo-lyase activity
LUM42_RS19630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LUM42_RS19640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LUM42_RS19645	COG1280	lysine exporter protein (LysE YggA)
LUM42_RS19650	COG0400	carboxylic ester hydrolase activity
LUM42_RS19655	COG0435	Glutathione S-transferase
LUM42_RS19660	COG0583	DNA-binding transcription factor activity
LUM42_RS19665	COG4145	pantothenate transmembrane transporter activity
LUM42_RS19675	COG2423	ornithine cyclodeaminase activity
LUM42_RS19690	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LUM42_RS19715	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LUM42_RS19725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LUM42_RS19745	COG2207	Transcriptional regulator
LUM42_RS19765	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LUM42_RS19775	COG0488	(ABC) transporter
LUM42_RS19925	COG1252	NADH dehydrogenase
LUM42_RS19935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LUM42_RS19940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LUM42_RS19945	COG4232	protein-disulfide reductase activity
LUM42_RS19955	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LUM42_RS19960	COG0110	maltose O-acetyltransferase activity
LUM42_RS19975	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LUM42_RS19975	COG3008	intermembrane lipid transfer
LUM42_RS19980	COG2995	paraquat-inducible protein a
LUM42_RS19985	COG0318	PFAM AMP-dependent synthetase and ligase
LUM42_RS19995	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_RS20000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LUM42_RS20010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LUM42_RS20020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUM42_RS20030	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LUM42_RS20035	COG0583	DNA-binding transcription factor activity
LUM42_RS20045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LUM42_RS20060	COG0513	Belongs to the DEAD box helicase family
LUM42_RS20065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LUM42_RS20085	COG0672	)-iron permease
LUM42_RS20090	COG4633	Protein conserved in bacteria
LUM42_RS20095	COG4628	conserved protein (DUF2132)
LUM42_RS20135	COG0789	Transcriptional regulator
LUM42_RS20140	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LUM42_RS20195	COG0454	-acetyltransferase
LUM42_RS20205	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_RS20240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LUM42_RS20250	COG0494	nUDIX hydrolase
LUM42_RS20255	COG1280	lysine exporter protein (LysE YggA)
LUM42_RS20265	COG0456	acetyltransferase
LUM42_RS20275	COG1335	isochorismatase
LUM42_RS20305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LUM42_RS20310	COG1309	transcriptional regulator
LUM42_RS20320	COG0583	DNA-binding transcription factor activity
LUM42_RS20330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LUM42_RS20345	COG2897	thiosulfate sulfurtransferase activity
LUM42_RS20350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LUM42_RS20360	COG0302	gtp cyclohydrolase
LUM42_RS20365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LUM42_RS20365	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LUM42_RS20370	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LUM42_RS20375	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LUM42_RS20390	COG1011	Hydrolase
LUM42_RS20395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LUM42_RS20405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LUM42_RS20410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUM42_RS20415	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LUM42_RS20425	COG3842	ATPase activity
LUM42_RS20445	COG2866	Carboxypeptidase
LUM42_RS20470	COG4166	transmembrane transport
LUM42_RS20475	COG4174	ABC transporter (Permease)
LUM42_RS20480	COG4239	(ABC) transporter, permease
LUM42_RS20485	COG4172	Belongs to the ABC transporter superfamily
LUM42_RS20490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LUM42_RS20510	COG4251	negative regulation of phosphorylation
LUM42_RS20510	COG3706	GGDEF domain
LUM42_RS20510	COG2203	Gaf domain
LUM42_RS20510	COG5001	Diguanylate cyclase
LUM42_RS20520	COG2199	diguanylate cyclase activity
LUM42_RS20535	COG2501	S4 domain
LUM42_RS20590	COG3710	Transcriptional regulator
LUM42_RS20620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUM42_RS20625	COG2207	Transcriptional regulator
LUM42_RS20625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LUM42_RS20635	COG2233	PERMEase
LUM42_RS20660	COG0765	amino acid transport
LUM42_RS20665	COG0765	amino acid transport
LUM42_RS20695	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LUM42_RS20720	COG0402	S-adenosylhomocysteine deaminase activity
LUM42_RS20725	COG2351	hydroxyisourate hydrolase activity
LUM42_RS20755	COG1079	Belongs to the binding-protein-dependent transport system permease family
LUM42_RS20760	COG4603	Belongs to the binding-protein-dependent transport system permease family
LUM42_RS20765	COG3845	ABC transporter
LUM42_RS20770	COG1309	transcriptional regulator
LUM42_RS20790	COG2199	diguanylate cyclase activity
LUM42_RS20805	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LUM42_RS20810	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LUM42_RS20835	COG3140	Belongs to the UPF0181 family
LUM42_RS20840	COG0023	Translation Initiation Factor
LUM42_RS20855	COG1181	Belongs to the D-alanine--D-alanine ligase family
LUM42_RS20865	COG0045	succinate-CoA ligase (ADP-forming) activity
LUM42_RS20865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUM42_RS20865	COG1042	CoA-binding domain protein
LUM42_RS20870	COG0583	DNA-binding transcription factor activity
LUM42_RS20875	COG4771	TonB-dependent receptor
LUM42_RS20885	COG4533	DNA binding
LUM42_RS20895	COG2050	protein possibly involved in aromatic compounds catabolism
LUM42_RS20905	COG2824	Alkylphosphonate utilization operon protein PhnA
LUM42_RS20920	COG0737	Belongs to the 5'-nucleotidase family
LUM42_RS20925	COG3593	DNA synthesis involved in DNA repair
LUM42_RS20935	COG0583	DNA-binding transcription factor activity
LUM42_RS20940	COG2116	formate transmembrane transporter activity
LUM42_RS20945	COG2353	YceI-like domain
LUM42_RS20950	COG3038	cytochrome b561
LUM42_RS20975	COG5001	Diguanylate cyclase
LUM42_RS20985	COG0243	molybdopterin cofactor binding
LUM42_RS20990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LUM42_RS20995	COG5002	protein histidine kinase activity
LUM42_RS20995	COG0784	Response regulator, receiver
LUM42_RS20995	COG2205	protein histidine kinase activity
LUM42_RS21000	COG3437	response regulator, receiver
LUM42_RS21010	COG2207	Transcriptional regulator
LUM42_RS21015	COG1064	alcohol dehydrogenase
LUM42_RS21020	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_RS21025	COG1846	Transcriptional regulator
LUM42_RS21030	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LUM42_RS21035	COG0523	cobalamin synthesis protein
LUM42_RS21050	COG0156	8-amino-7-oxononanoate synthase activity
LUM42_RS21055	COG0784	Response regulator, receiver
LUM42_RS21055	COG2205	protein histidine kinase activity
LUM42_RS21060	COG0419	ATPase involved in DNA repair
LUM42_RS21065	COG0420	3'-5' exonuclease activity
LUM42_RS21070	COG1609	Transcriptional regulator
LUM42_RS21075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUM42_RS21075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUM42_RS21080	COG1105	Belongs to the carbohydrate kinase PfkB family
LUM42_RS21085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LUM42_RS21085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LUM42_RS21085	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LUM42_RS21090	COG4067	protein conserved in archaea
LUM42_RS21090	COG0189	ligase activity
LUM42_RS21100	COG0602	queuosine metabolic process
LUM42_RS21105	COG1328	CTP reductase activity
LUM42_RS21190	COG1073	alpha beta
LUM42_RS21195	COG0583	DNA-binding transcription factor activity
LUM42_RS21200	COG0454	-acetyltransferase
LUM42_RS21210	COG2207	Transcriptional regulator
LUM42_RS21220	COG1073	alpha beta
LUM42_RS21225	COG1073	alpha beta
LUM42_RS21230	COG1902	pentaerythritol trinitrate reductase activity
LUM42_RS21275	COG0583	DNA-binding transcription factor activity
LUM42_RS21280	COG1280	lysine exporter protein (LysE YggA)
LUM42_RS21285	COG0745	RESPONSE REGULATOR receiver
LUM42_RS21295	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LUM42_RS21300	COG0840	transmembrane signaling receptor activity
LUM42_RS21320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LUM42_RS21325	COG0840	transmembrane signaling receptor activity
LUM42_RS21330	COG2814	Major facilitator Superfamily
LUM42_RS21345	COG3069	C4-dicarboxylate transmembrane transporter activity
LUM42_RS21350	COG2197	response regulator
LUM42_RS21355	COG3850	Histidine kinase
LUM42_RS21370	COG0243	molybdopterin cofactor binding
LUM42_RS21380	COG3005	denitrification pathway
LUM42_RS21390	COG4166	transmembrane transport
LUM42_RS21410	COG0183	Belongs to the thiolase family
LUM42_RS21420	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUM42_RS21425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUM42_RS21450	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LUM42_RS21460	COG2207	Transcriptional regulator
LUM42_RS21465	COG1979	alcohol dehydrogenase
LUM42_RS21475	COG0784	Response regulator, receiver
LUM42_RS21475	COG2205	protein histidine kinase activity
LUM42_RS21475	COG2198	Histidine kinase
LUM42_RS21480	COG1879	ABC-type sugar transport system periplasmic component
LUM42_RS21485	COG1803	Methylglyoxal synthase
LUM42_RS21490	COG1335	isochorismatase
LUM42_RS21495	COG0210	DNA helicase
LUM42_RS21535	COG1289	transmembrane transporter activity
LUM42_RS21550	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LUM42_RS21555	COG4149	molybdate abc transporter
LUM42_RS21560	COG0725	ABC transporter, periplasmic molybdate-binding protein
LUM42_RS21565	COG1492	cobalamin metabolic process
LUM42_RS21585	COG5002	protein histidine kinase activity
LUM42_RS21585	COG0784	Response regulator, receiver
LUM42_RS21590	COG1879	ABC-type sugar transport system periplasmic component
LUM42_RS21595	COG2827	Endonuclease containing a URI domain
LUM42_RS21600	COG3132	Protein of unknown function, DUF480
LUM42_RS21615	COG4974	Belongs to the 'phage' integrase family
LUM42_RS21770	COG2184	nucleotidyltransferase activity
LUM42_RS21775	COG4695	Portal protein
LUM42_RS21815	COG4386	tail sheath protein
LUM42_RS21865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LUM42_RS21870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LUM42_RS21875	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
LUM42_RS21880	COG0247	lactate metabolic process
LUM42_RS21895	COG0438	transferase activity, transferring glycosyl groups
LUM42_RS21895	COG0297	glycogen (starch) synthase activity
LUM42_RS21900	COG0438	transferase activity, transferring glycosyl groups
LUM42_RS21950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LUM42_RS21955	COG3118	belongs to the thioredoxin family
LUM42_RS21985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LUM42_RS21985	COG1648	precorrin-2 dehydrogenase activity
LUM42_RS22000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LUM42_RS22005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LUM42_RS22010	COG4160	amino acid transport
LUM42_RS22015	COG4215	(ABC) transporter
LUM42_RS22020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUM42_RS22025	COG1126	abc transporter atp-binding protein
LUM42_RS22055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LUM42_RS22060	COG1120	ATPase activity
LUM42_RS22075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LUM42_RS22085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LUM42_RS22100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LUM42_RS22110	COG1070	Carbohydrate kinase
LUM42_RS22120	COG2390	Transcriptional regulator
LUM42_RS22125	COG1294	oxidase, subunit
LUM42_RS22130	COG1271	oxidase subunit
LUM42_RS22135	COG0243	molybdopterin cofactor binding
LUM42_RS22140	COG3781	membrane
LUM42_RS22145	COG0583	DNA-binding transcription factor activity
LUM42_RS22150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LUM42_RS22165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUM42_RS22175	COG0330	HflC and HflK could
LUM42_RS22195	COG2207	Transcriptional regulator
LUM42_RS22195	COG1917	Cupin 2, conserved barrel domain protein
LUM42_RS22200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LUM42_RS22215	COG1609	Transcriptional regulator
LUM42_RS22215	COG2207	Transcriptional regulator
LUM42_RS22220	COG4604	ABC transporter, ATP-binding protein
LUM42_RS22225	COG4605	iron ion homeostasis
LUM42_RS22230	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_RS22240	COG0121	glutamine amidotransferase
LUM42_RS22255	COG5380	lipid catabolic process
LUM42_RS22260	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LUM42_RS22265	COG0840	transmembrane signaling receptor activity
LUM42_RS22270	COG1522	sequence-specific DNA binding
LUM42_RS22290	COG2814	Major facilitator Superfamily
LUM42_RS22300	COG0840	transmembrane signaling receptor activity
LUM42_RS22315	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LUM42_RS22320	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LUM42_RS22325	COG3279	Response regulator of the LytR AlgR family
LUM42_RS22330	COG3275	phosphorelay sensor kinase activity
LUM42_RS22335	COG4989	oxidoreductase activity
LUM42_RS22350	COG0366	Alpha amylase catalytic
LUM42_RS22355	COG3227	Zinc metalloprotease (Elastase)
LUM42_RS22360	COG3047	cAMP biosynthetic process
LUM42_RS22370	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LUM42_RS22380	COG0351	phosphomethylpyrimidine kinase
LUM42_RS22385	COG1116	anion transmembrane transporter activity
LUM42_RS22390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUM42_RS22395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUM42_RS22400	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LUM42_RS22415	COG1132	(ABC) transporter
LUM42_RS22420	COG1132	(ABC) transporter
LUM42_RS22430	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LUM42_RS22435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LUM42_RS22455	COG1278	Cold shock
LUM42_RS22460	COG1063	alcohol dehydrogenase
LUM42_RS22465	COG0156	8-amino-7-oxononanoate synthase activity
LUM42_RS22470	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_RS22475	COG3284	Transcriptional regulator
LUM42_RS22485	COG0346	lactoylglutathione lyase activity
LUM42_RS22505	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LUM42_RS22515	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LUM42_RS22520	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LUM42_RS22525	COG0363	glucosamine-6-phosphate deaminase activity
LUM42_RS22530	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LUM42_RS22570	COG0531	amino acid
LUM42_RS22585	COG1929	Belongs to the glycerate kinase type-1 family
LUM42_RS22590	COG2610	gluconate transmembrane transporter activity
LUM42_RS22595	COG3835	regulator
LUM42_RS22600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LUM42_RS22605	COG4533	DNA binding
LUM42_RS22660	COG3188	usher protein
LUM42_RS22665	COG3121	Chaperone
LUM42_RS22685	COG1566	PFAM secretion protein HlyD family protein
LUM42_RS22700	COG1686	Belongs to the peptidase S11 family
LUM42_RS22710	COG0765	amino acid transport
LUM42_RS22725	COG1522	sequence-specific DNA binding
LUM42_RS22730	COG0010	Belongs to the arginase family
LUM42_RS22735	COG1166	arginine decarboxylase activity
LUM42_RS22745	COG4175	Glycine betaine
LUM42_RS22750	COG4176	ABC-type proline glycine betaine transport system permease component
LUM42_RS22755	COG2113	Glycine betaine
LUM42_RS22775	COG2239	Acts as a magnesium transporter
LUM42_RS22780	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LUM42_RS22785	COG0459	protein refolding
LUM42_RS22795	COG0113	porphobilinogen synthase activity
LUM42_RS22805	COG0784	Response regulator, receiver
LUM42_RS22805	COG3437	response regulator, receiver
LUM42_RS22830	COG0527	aspartate kinase activity
LUM42_RS22835	COG0662	Cupin 2, conserved barrel domain protein
LUM42_RS22840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUM42_RS22845	COG0456	acetyltransferase
LUM42_RS22850	COG1917	Cupin 2, conserved barrel domain protein
LUM42_RS22850	COG4977	sequence-specific DNA binding
LUM42_RS22855	COG0861	Integral membrane protein TerC family
LUM42_RS22865	COG0534	Mate efflux family protein
LUM42_RS22870	COG2154	pterin-4-alpha-carbinolamine dehydratase
LUM42_RS22875	COG3186	Phenylalanine-4-hydroxylase
LUM42_RS22880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LUM42_RS22915	COG1022	Amp-dependent synthetase and ligase
LUM42_RS22950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LUM42_RS22955	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LUM42_RS22955	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LUM42_RS22965	COG2197	response regulator
LUM42_RS22970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUM42_RS22970	COG2205	protein histidine kinase activity
LUM42_RS22975	COG3300	MHYT domain
LUM42_RS22975	COG5001	Diguanylate cyclase
LUM42_RS23005	COG3036	rescue of stalled ribosome
LUM42_RS23010	COG1278	Cold shock
LUM42_RS23015	COG4681	YaeQ
LUM42_RS23020	COG3706	GGDEF domain
LUM42_RS23025	COG1017	nitric oxide dioxygenase activity
LUM42_RS23025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LUM42_RS23030	COG3604	Transcriptional regulator
LUM42_RS23040	COG2195	Cleaves the N-terminal amino acid of tripeptides
LUM42_RS23045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LUM42_RS23055	COG0366	Alpha amylase catalytic
LUM42_RS23070	COG0840	transmembrane signaling receptor activity
LUM42_RS23075	COG0714	Associated with various cellular activities
LUM42_RS23095	COG2304	oxidoreductase activity
LUM42_RS23110	COG5001	Diguanylate cyclase
LUM42_RS23120	COG2205	protein histidine kinase activity
LUM42_RS23120	COG0784	Response regulator, receiver
LUM42_RS23120	COG5002	protein histidine kinase activity
LUM42_RS23135	COG3724	N-succinylarginine dihydrolase activity
LUM42_RS23140	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_RS23165	COG4948	Mandelate Racemase Muconate Lactonizing
LUM42_RS23190	COG0583	DNA-binding transcription factor activity
LUM42_RS23200	COG3171	Protein conserved in bacteria
LUM42_RS23205	COG0589	response to stress
LUM42_RS23215	COG3530	Putative quorum-sensing-regulated virulence factor
LUM42_RS23225	COG0579	oxidoreductase
LUM42_RS23240	COG2204	response regulator
LUM42_RS23270	COG5001	Diguanylate cyclase
LUM42_RS23270	COG3300	MHYT domain
LUM42_RS23275	COG2271	Major facilitator Superfamily
LUM42_RS23280	COG0584	glycerophosphoryl diester phosphodiesterase
LUM42_RS23285	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LUM42_RS23290	COG0583	DNA-binding transcription factor activity
LUM42_RS23295	COG1609	Transcriptional regulator
LUM42_RS23300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUM42_RS23305	COG1879	ABC-type sugar transport system periplasmic component
LUM42_RS23310	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUM42_RS23315	COG1129	ABC transporter
LUM42_RS23320	COG1869	D-ribose catabolic process
LUM42_RS23340	COG3409	Peptidoglycan-binding domain 1 protein
LUM42_RS23340	COG3501	Rhs element vgr protein
LUM42_RS23410	COG3501	Rhs element vgr protein
LUM42_RS23435	COG3829	transcription factor binding
LUM42_RS23510	COG1846	Transcriptional regulator
LUM42_RS23525	COG0564	pseudouridine synthase activity
LUM42_RS23530	COG1309	transcriptional regulator
LUM42_RS23535	COG2130	NADP-dependent
LUM42_RS23550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LUM42_RS23580	COG3842	ATPase activity
LUM42_RS23590	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LUM42_RS23595	COG0656	L-ascorbic acid biosynthetic process
LUM42_RS23600	COG1902	pentaerythritol trinitrate reductase activity
LUM42_RS23605	COG0583	DNA-binding transcription factor activity
LUM42_RS23610	COG2814	Major facilitator Superfamily
LUM42_RS23630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LUM42_RS23645	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LUM42_RS23655	COG4702	Belongs to the UPF0303 family
LUM42_RS23660	COG0673	inositol 2-dehydrogenase activity
LUM42_RS23665	COG1349	DNA-binding transcription factor activity
LUM42_RS23675	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LUM42_RS23695	COG3240	lipase activity
LUM42_RS23700	COG3477	response to acidic pH
LUM42_RS23705	COG0697	spore germination
LUM42_RS23710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUM42_RS23725	COG2207	Transcriptional regulator
LUM42_RS23725	COG1917	Cupin 2, conserved barrel domain protein
LUM42_RS23745	COG3447	MASE1 domain protein
LUM42_RS23745	COG5001	Diguanylate cyclase
LUM42_RS23745	COG5002	protein histidine kinase activity
LUM42_RS23755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LUM42_RS23770	COG0109	protoheme IX farnesyltransferase activity
LUM42_RS23805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LUM42_RS23810	COG1565	acr, cog1565
LUM42_RS23810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LUM42_RS23815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LUM42_RS23820	COG1902	pentaerythritol trinitrate reductase activity
LUM42_RS23830	COG1280	lysine exporter protein (LysE YggA)
LUM42_RS23855	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUM42_RS23860	COG1846	Transcriptional regulator
LUM42_RS23865	COG1764	response to oxidative stress
LUM42_RS23875	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LUM42_RS23885	COG2814	Major facilitator Superfamily
LUM42_RS23890	COG0583	DNA-binding transcription factor activity
LUM42_RS23895	COG5001	Diguanylate cyclase
LUM42_RS23900	COG0739	heme binding
LUM42_RS23915	COG0659	secondary active sulfate transmembrane transporter activity
LUM42_RS23920	COG3314	Sporulation integral membrane protein YlbJ
LUM42_RS23930	COG2199	diguanylate cyclase activity
LUM42_RS23935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LUM42_RS23940	COG0581	inorganic phosphate transmembrane transporter activity
LUM42_RS23945	COG0573	inorganic phosphate transmembrane transporter activity
LUM42_RS23950	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LUM42_RS23960	COG0513	Belongs to the DEAD box helicase family
LUM42_RS23970	COG1388	LysM domain
LUM42_RS23970	COG1376	ErfK ybiS ycfS ynhG family protein
LUM42_RS23975	COG0415	Belongs to the DNA photolyase family
LUM42_RS23980	COG0789	Transcriptional regulator
LUM42_RS23985	COG3272	Protein of unknown function (DUF1722)
LUM42_RS23990	COG0813	purine-nucleoside phosphorylase activity
LUM42_RS24005	COG3706	GGDEF domain
LUM42_RS24015	COG1566	PFAM secretion protein HlyD family protein
LUM42_RS24050	COG0786	glutamate:sodium symporter activity
LUM42_RS24075	COG1162	GTPase activity
LUM42_RS24080	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LUM42_RS24095	COG4580	involved in the transport of maltose and maltodextrins
LUM42_RS24105	COG1132	(ABC) transporter
LUM42_RS24125	COG3383	formate dehydrogenase (NAD+) activity
LUM42_RS24140	COG0840	transmembrane signaling receptor activity
LUM42_RS24150	COG1131	(ABC) transporter
LUM42_RS24155	COG2188	Transcriptional regulator
LUM42_RS24165	COG3033	Beta-eliminating lyase
LUM42_RS24170	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LUM42_RS24175	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LUM42_RS24180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUM42_RS24185	COG0471	metal ion transport
LUM42_RS24210	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LUM42_RS24260	COG3501	Rhs element vgr protein
LUM42_RS24270	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LUM42_RS24275	COG1640	4-alpha-glucanotransferase
LUM42_RS24280	COG0058	SHG alpha-glucan phosphorylase activity
LUM42_RS24290	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LUM42_RS24335	COG0110	maltose O-acetyltransferase activity