locus-tag	class	description
OCU28_RS00010	COG0592	DNA-directed DNA polymerase activity
OCU28_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OCU28_RS00020	COG0187	DNA topoisomerase II activity
OCU28_RS00025	COG0204	Acyl-transferase
OCU28_RS00030	COG0071	Belongs to the small heat shock protein (HSP20) family
OCU28_RS00035	COG3977	Valine--pyruvate aminotransferase
OCU28_RS00040	COG0751	glycine-tRNA ligase activity
OCU28_RS00045	COG0752	glycyl-tRNA synthetase alpha subunit
OCU28_RS00065	COG0604	alcohol dehydrogenase
OCU28_RS00070	COG0183	Belongs to the thiolase family
OCU28_RS00080	COG1739	Uncharacterized protein family UPF0029
OCU28_RS00085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OCU28_RS00090	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
OCU28_RS00135	COG3071	HemY protein
OCU28_RS00140	COG2959	enzyme of heme biosynthesis
OCU28_RS00150	COG0181	hydroxymethylbilane synthase activity
OCU28_RS00155	COG3072	Adenylate cyclase
OCU28_RS00160	COG1965	Belongs to the frataxin family
OCU28_RS00170	COG0019	diaminopimelate decarboxylase activity
OCU28_RS00175	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OCU28_RS00185	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OCU28_RS00190	COG1011	Hydrolase
OCU28_RS00195	COG3148	PFAM DTW domain containing protein
OCU28_RS00205	COG0561	phosphatase activity
OCU28_RS00210	COG2267	carboxylic ester hydrolase activity
OCU28_RS00220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OCU28_RS00265	COG0601	transmembrane transport
OCU28_RS00270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCU28_RS00285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCU28_RS00290	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OCU28_RS00295	COG0339	signal peptide processing
OCU28_RS00300	COG1522	sequence-specific DNA binding
OCU28_RS00305	COG0742	ribosomal rna small subunit methyltransferase
OCU28_RS00320	COG1528	Iron-storage protein
OCU28_RS00330	COG2081	HI0933 family
OCU28_RS00350	COG0697	spore germination
OCU28_RS00355	COG2226	methyltransferase
OCU28_RS00360	COG3165	ubiquinone biosynthetic process from chorismate
OCU28_RS00365	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OCU28_RS00370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OCU28_RS00375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OCU28_RS00380	COG0805	protein transport
OCU28_RS00385	COG0084	hydrolase, TatD family'
OCU28_RS00395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCU28_RS00395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCU28_RS00400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OCU28_RS00415	COG3078	GTPase activator activity
OCU28_RS00430	COG2204	response regulator
OCU28_RS00435	COG3852	Histidine kinase
OCU28_RS00440	COG0174	glutamine synthetase
OCU28_RS00445	COG1217	gtp-binding protein TYPA
OCU28_RS00455	COG1490	D-aminoacyl-tRNA deacylase activity
OCU28_RS00460	COG0456	acetyltransferase
OCU28_RS00480	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OCU28_RS00485	COG3031	protein transport across the cell outer membrane
OCU28_RS00495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OCU28_RS00500	COG1459	type II secretion system
OCU28_RS00505	COG2165	general secretion pathway protein
OCU28_RS00510	COG2165	general secretion pathway protein
OCU28_RS00515	COG2165	general secretion pathway protein
OCU28_RS00520	COG4795	General secretion pathway protein
OCU28_RS00525	COG3156	type II secretion system protein K
OCU28_RS00530	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
OCU28_RS00535	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
OCU28_RS00545	COG0494	nUDIX hydrolase
OCU28_RS00550	COG1218	3'(2'),5'-bisphosphate nucleotidase
OCU28_RS00555	COG0596	Alpha beta hydrolase
OCU28_RS00560	COG1040	competence protein
OCU28_RS00580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OCU28_RS00590	COG2183	response to ionizing radiation
OCU28_RS00595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OCU28_RS00600	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OCU28_RS00605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OCU28_RS00630	COG0463	Glycosyl transferase, family 2
OCU28_RS00635	COG0859	PFAM glycosyl transferase family 9
OCU28_RS00640	COG3642	lipopolysaccharide core region biosynthetic process
OCU28_RS00645	COG1519	Transferase
OCU28_RS00670	COG0859	PFAM glycosyl transferase family 9
OCU28_RS00675	COG1560	Kdo2-lipid A biosynthetic process
OCU28_RS00680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OCU28_RS00695	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OCU28_RS00700	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OCU28_RS00710	COG1609	Transcriptional regulator
OCU28_RS00715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OCU28_RS00720	COG0254	rRNA binding
OCU28_RS00725	COG0281	malic enzyme
OCU28_RS00730	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
OCU28_RS00735	COG0626	cystathionine gamma-synthase activity
OCU28_RS00740	COG0460	homoserine dehydrogenase
OCU28_RS00740	COG0527	aspartate kinase activity
OCU28_RS00745	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OCU28_RS00750	COG1695	Transcriptional regulator
OCU28_RS00755	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OCU28_RS00760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OCU28_RS00765	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OCU28_RS00770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OCU28_RS00775	COG0137	argininosuccinate synthase activity
OCU28_RS00780	COG0165	Argininosuccinate lyase
OCU28_RS00780	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OCU28_RS00785	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OCU28_RS00785	COG0678	peroxiredoxin activity
OCU28_RS00795	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OCU28_RS00825	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OCU28_RS00835	COG0338	D12 class N6 adenine-specific DNA methyltransferase
OCU28_RS00840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OCU28_RS00845	COG0546	phosphoglycolate phosphatase activity
OCU28_RS00850	COG0180	Tryptophanyl-tRNA synthetase
OCU28_RS00855	COG0512	Glutamine amidotransferase of anthranilate synthase
OCU28_RS00860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OCU28_RS00870	COG1012	belongs to the aldehyde dehydrogenase family
OCU28_RS00885	COG3954	Phosphoribulokinase
OCU28_RS00890	COG3089	Belongs to the UPF0270 family
OCU28_RS00895	COG0429	hydrolase of the alpha beta-hydrolase fold
OCU28_RS00905	COG0488	(ABC) transporter
OCU28_RS00910	COG2249	NAD(P)H dehydrogenase (quinone) activity
OCU28_RS00925	COG1047	Peptidyl-prolyl cis-trans
OCU28_RS00930	COG1446	asparaginase
OCU28_RS00940	COG0545	Peptidyl-prolyl cis-trans isomerase
OCU28_RS00945	COG2964	Protein conserved in bacteria
OCU28_RS00950	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OCU28_RS00955	COG2923	Belongs to the DsrF TusC family
OCU28_RS00975	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OCU28_RS00980	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OCU28_RS00985	COG0051	transcription antitermination factor activity, RNA binding
OCU28_RS00990	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OCU28_RS00995	COG0088	Forms part of the polypeptide exit tunnel
OCU28_RS01000	COG0089	rRNA binding
OCU28_RS01005	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OCU28_RS01010	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OCU28_RS01015	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OCU28_RS01020	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OCU28_RS01025	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OCU28_RS01030	COG0255	Belongs to the universal ribosomal protein uL29 family
OCU28_RS01035	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OCU28_RS01045	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OCU28_RS01060	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OCU28_RS01065	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OCU28_RS01080	COG1841	ribosomal large subunit assembly
OCU28_RS01085	COG0200	Binds to the 23S rRNA
OCU28_RS01090	COG0201	protein transport
OCU28_RS01095	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OCU28_RS01100	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OCU28_RS01115	COG0202	RNA polymerase activity
OCU28_RS01120	COG0203	ribosomal protein L17
OCU28_RS01135	COG0545	Peptidyl-prolyl cis-trans isomerase
OCU28_RS01140	COG3061	Opacity-associated protein A
OCU28_RS01140	COG3266	domain, Protein
OCU28_RS01145	COG2153	protein acetylation
OCU28_RS01150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OCU28_RS01150	COG1648	precorrin-2 dehydrogenase activity
OCU28_RS01180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCU28_RS01185	COG0729	surface antigen
OCU28_RS01195	COG2105	PFAM AIG2 family protein
OCU28_RS01200	COG3040	lipid binding
OCU28_RS01210	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OCU28_RS01215	COG0163	prenyltransferase activity
OCU28_RS01220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OCU28_RS01225	COG0564	pseudouridine synthase activity
OCU28_RS01230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OCU28_RS01245	COG2358	TRAP transporter, solute receptor (TAXI family
OCU28_RS01250	COG1438	arginine binding
OCU28_RS01255	COG0039	L-malate dehydrogenase activity
OCU28_RS01265	COG0142	geranyltranstransferase activity
OCU28_RS01270	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OCU28_RS01275	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OCU28_RS01280	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OCU28_RS01285	COG1289	transmembrane transporter activity
OCU28_RS01290	COG2966	Psort location CytoplasmicMembrane, score
OCU28_RS01295	COG3610	response to peptide
OCU28_RS01310	COG2967	ApaG domain
OCU28_RS01315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OCU28_RS01325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OCU28_RS01330	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OCU28_RS01335	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OCU28_RS01345	COG0066	3-isopropylmalate dehydratase activity
OCU28_RS01355	COG0473	3-isopropylmalate dehydrogenase activity
OCU28_RS01370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCU28_RS01385	COG0583	DNA-binding transcription factor activity
OCU28_RS01390	COG1022	Amp-dependent synthetase and ligase
OCU28_RS01395	COG0028	Belongs to the TPP enzyme family
OCU28_RS01400	COG0440	acetolactate synthase activity
OCU28_RS01405	COG0469	pyruvate kinase activity
OCU28_RS01410	COG0673	inositol 2-dehydrogenase activity
OCU28_RS01420	COG0534	Mate efflux family protein
OCU28_RS01425	COG2116	formate transmembrane transporter activity
OCU28_RS01440	COG0745	RESPONSE REGULATOR receiver
OCU28_RS01455	COG3713	MltA-interacting MipA family protein
OCU28_RS01470	COG0358	DNA primase activity
OCU28_RS01475	COG1610	YqeY-like protein
OCU28_RS01480	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OCU28_RS01485	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OCU28_RS01495	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OCU28_RS01500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OCU28_RS01505	COG1968	undecaprenyl-diphosphatase activity
OCU28_RS01510	COG0617	tRNA 3'-terminal CCA addition
OCU28_RS01515	COG3409	Peptidoglycan-binding domain 1 protein
OCU28_RS01515	COG3267	Type II secretory pathway component ExeA
OCU28_RS01525	COG4991	sh3 domain protein
OCU28_RS01530	COG0306	phosphate transporter
OCU28_RS01535	COG1392	Phosphate transport regulator
OCU28_RS01540	COG3025	triphosphatase activity
OCU28_RS01545	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OCU28_RS01555	COG1538	Outer membrane efflux protein
OCU28_RS01560	COG0494	nUDIX hydrolase
OCU28_RS01565	COG3151	Protein conserved in bacteria
OCU28_RS01575	COG3150	esterase
OCU28_RS01605	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OCU28_RS01615	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OCU28_RS01620	COG0723	plastoquinol--plastocyanin reductase activity
OCU28_RS01625	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OCU28_RS01630	COG2857	Cytochrome c1
OCU28_RS01635	COG0625	glutathione transferase activity
OCU28_RS01640	COG2969	positive regulation of protein catabolic process
OCU28_RS01645	COG2823	Periplasmic or secreted lipoprotein
OCU28_RS01660	COG3107	peptidoglycan biosynthetic process
OCU28_RS01665	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OCU28_RS01680	COG3116	cell division
OCU28_RS01685	COG0768	penicillin binding
OCU28_RS01695	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OCU28_RS01705	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OCU28_RS01710	COG0772	Belongs to the SEDS family
OCU28_RS01715	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OCU28_RS01720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OCU28_RS01725	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OCU28_RS01730	COG0849	cell division
OCU28_RS01735	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OCU28_RS01740	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
OCU28_RS01750	COG0653	protein targeting
OCU28_RS01765	COG0505	Belongs to the CarA family
OCU28_RS01770	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OCU28_RS01775	COG0730	response to heat
OCU28_RS01780	COG0583	DNA-binding transcription factor activity
OCU28_RS01785	COG2860	membrane
OCU28_RS01790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OCU28_RS01805	COG0070	glutamate synthase
OCU28_RS01805	COG0069	glutamate synthase activity
OCU28_RS01805	COG0067	glutamate synthase
OCU28_RS01810	COG1242	4 iron, 4 sulfur cluster binding
OCU28_RS01815	COG0784	Response regulator, receiver
OCU28_RS01815	COG2198	Histidine kinase
OCU28_RS01815	COG5002	protein histidine kinase activity
OCU28_RS01825	COG0745	RESPONSE REGULATOR receiver
OCU28_RS01840	COG0083	homoserine kinase activity
OCU28_RS01845	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OCU28_RS01875	COG1115	amino acid carrier protein
OCU28_RS01880	COG3022	response to hydroperoxide
OCU28_RS01890	COG0513	Belongs to the DEAD box helicase family
OCU28_RS01900	COG0716	FMN binding
OCU28_RS01905	COG4974	Belongs to the 'phage' integrase family
OCU28_RS01910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OCU28_RS01915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OCU28_RS01925	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OCU28_RS01930	COG0517	IMP dehydrogenase activity
OCU28_RS01935	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OCU28_RS01940	COG0343	queuine tRNA-ribosyltransferase activity
OCU28_RS01945	COG1862	Preprotein translocase
OCU28_RS01950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OCU28_RS01955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OCU28_RS01960	COG1047	Peptidyl-prolyl cis-trans
OCU28_RS01965	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OCU28_RS01970	COG1966	Carbon starvation protein
OCU28_RS01985	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OCU28_RS01990	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OCU28_RS02000	COG3279	Response regulator of the LytR AlgR family
OCU28_RS02005	COG3275	phosphorelay sensor kinase activity
OCU28_RS02010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OCU28_RS02015	COG0287	Prephenate dehydrogenase
OCU28_RS02015	COG1605	Chorismate mutase
OCU28_RS02020	COG0488	(ABC) transporter
OCU28_RS02030	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
OCU28_RS02035	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
OCU28_RS02040	COG0077	Prephenate dehydratase
OCU28_RS02040	COG1605	Chorismate mutase
OCU28_RS02045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OCU28_RS02050	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OCU28_RS02055	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCU28_RS02070	COG0542	response to heat
OCU28_RS02120	COG0697	spore germination
OCU28_RS02130	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OCU28_RS02135	COG0826	peptidase U32
OCU28_RS02140	COG2974	May be involved in recombination
OCU28_RS02145	COG0745	RESPONSE REGULATOR receiver
OCU28_RS02150	COG5002	protein histidine kinase activity
OCU28_RS02165	COG0573	inorganic phosphate transmembrane transporter activity
OCU28_RS02170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OCU28_RS02175	COG0704	Plays a role in the regulation of phosphate uptake
OCU28_RS02185	COG0450	alkyl hydroperoxide reductase
OCU28_RS02190	COG0583	DNA-binding transcription factor activity
OCU28_RS02200	COG3066	DNA modification
OCU28_RS02205	COG0494	nUDIX hydrolase
OCU28_RS02210	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
OCU28_RS02220	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OCU28_RS02225	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OCU28_RS02235	COG1283	sodium-dependent phosphate transmembrane transporter activity
OCU28_RS02240	COG0583	DNA-binding transcription factor activity
OCU28_RS02245	COG0268	Binds directly to 16S ribosomal RNA
OCU28_RS02250	COG0728	peptidoglycan biosynthetic process
OCU28_RS02255	COG0196	riboflavin kinase activity
OCU28_RS02260	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OCU28_RS02270	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OCU28_RS02285	COG0779	Required for maturation of 30S ribosomal subunits
OCU28_RS02290	COG0195	Participates in both transcription termination and antitermination
OCU28_RS02305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OCU28_RS02325	COG0826	peptidase U32
OCU28_RS02330	COG0826	peptidase U32
OCU28_RS02335	COG3154	lipid carrier protein
OCU28_RS02340	COG3153	acetyltransferase
OCU28_RS02350	COG0456	acetyltransferase
OCU28_RS02355	COG1151	hydroxylamine reductase activity
OCU28_RS02360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OCU28_RS02365	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OCU28_RS02370	COG0583	DNA-binding transcription factor activity
OCU28_RS02385	COG0084	hydrolase, TatD family'
OCU28_RS02390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OCU28_RS02400	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OCU28_RS02405	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OCU28_RS02410	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OCU28_RS02415	COG0813	purine-nucleoside phosphorylase activity
OCU28_RS02425	COG0560	Phosphoserine phosphatase
OCU28_RS02430	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OCU28_RS02435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OCU28_RS02445	COG1022	Amp-dependent synthetase and ligase
OCU28_RS02480	COG4964	Belongs to the GSP D family
OCU28_RS02520	COG2171	N-acyltransferase activity
OCU28_RS02525	COG2095	MarC family integral membrane protein
OCU28_RS02530	COG3141	response to X-ray
OCU28_RS02535	COG0583	DNA-binding transcription factor activity
OCU28_RS02545	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OCU28_RS02550	COG1074	ATP-dependent DNA helicase activity
OCU28_RS02555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OCU28_RS02560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OCU28_RS02560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OCU28_RS02565	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
OCU28_RS02570	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OCU28_RS02575	COG2166	iron-sulfur cluster assembly
OCU28_RS02580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OCU28_RS02585	COG0693	protein deglycase activity
OCU28_RS02590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OCU28_RS02610	COG1595	DNA-templated transcription, initiation
OCU28_RS02620	COG2211	Major facilitator Superfamily
OCU28_RS02625	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OCU28_RS02635	COG2813	Specifically methylates the guanine in position
OCU28_RS02640	COG0271	Belongs to the BolA IbaG family
OCU28_RS02645	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OCU28_RS02650	COG1805	sodium ion transport
OCU28_RS02660	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OCU28_RS02665	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OCU28_RS02670	COG2871	sodium ion transport
OCU28_RS02675	COG1477	protein flavinylation
OCU28_RS02690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OCU28_RS02710	COG0442	prolyl-tRNA aminoacylation
OCU28_RS02715	COG1720	tRNA m6t6A37 methyltransferase activity
OCU28_RS02720	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OCU28_RS02730	COG1464	Belongs to the NlpA lipoprotein family
OCU28_RS02735	COG2011	ABC-type metal ion transport system permease component
OCU28_RS02740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OCU28_RS02745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OCU28_RS02750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OCU28_RS02760	COG1451	nucleotide metabolic process
OCU28_RS02775	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OCU28_RS02780	COG0321	lipoyl(octanoyl) transferase activity
OCU28_RS02785	COG2921	Belongs to the UPF0250 family
OCU28_RS02790	COG1686	Belongs to the peptidase S11 family
OCU28_RS02795	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OCU28_RS02800	COG0772	Belongs to the SEDS family
OCU28_RS02805	COG0768	penicillin binding
OCU28_RS02810	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OCU28_RS02815	COG0799	negative regulation of ribosome biogenesis
OCU28_RS02820	COG1466	dna polymerase III delta subunit
OCU28_RS02830	COG0495	leucyl-tRNA aminoacylation
OCU28_RS02840	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OCU28_RS02845	COG4535	Mg2 and Co2 transporter CorC
OCU28_RS02855	COG1702	phosphate starvation-inducible protein PhoH
OCU28_RS02865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OCU28_RS02870	COG2706	6-phosphogluconolactonase activity
OCU28_RS02955	COG0193	aminoacyl-tRNA hydrolase activity
OCU28_RS02960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OCU28_RS02965	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OCU28_RS02970	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OCU28_RS02975	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OCU28_RS02980	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OCU28_RS02985	COG2890	protein-(glutamine-N5) methyltransferase activity
OCU28_RS02995	COG2912	Transglutaminase-like superfamily
OCU28_RS03000	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OCU28_RS03005	COG0737	Belongs to the 5'-nucleotidase family
OCU28_RS03010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OCU28_RS03020	COG2840	Smr protein MutS2
OCU28_RS03050	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OCU28_RS03090	COG0544	peptidyl-prolyl cis-trans isomerase activity
OCU28_RS03105	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OCU28_RS03110	COG0776	regulation of translation
OCU28_RS03115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OCU28_RS03120	COG1555	photosystem II stabilization
OCU28_RS03120	COG1596	polysaccharide export
OCU28_RS03135	COG0232	Belongs to the dGTPase family. Type 2 subfamily
OCU28_RS03140	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
OCU28_RS03145	COG0436	Aminotransferase
OCU28_RS03150	COG1169	isochorismate synthase
OCU28_RS03155	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OCU28_RS03195	COG0857	belongs to the CobB CobQ family
OCU28_RS03195	COG0280	phosphate acetyltransferase
OCU28_RS03200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OCU28_RS03205	COG3092	negative regulation of chromosome organization
OCU28_RS03215	COG4120	Belongs to the binding-protein-dependent transport system permease family
OCU28_RS03220	COG1122	ATPase activity
OCU28_RS03235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OCU28_RS03240	COG0653	protein targeting
OCU28_RS03245	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OCU28_RS03255	COG2186	Transcriptional regulator
OCU28_RS03275	COG1121	(ABC) transporter
OCU28_RS03280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OCU28_RS03285	COG0803	Belongs to the bacterial solute-binding protein 9 family
OCU28_RS03295	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
OCU28_RS03325	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OCU28_RS03345	COG2814	Major facilitator Superfamily
OCU28_RS03350	COG1917	Cupin 2, conserved barrel domain protein
OCU28_RS03360	COG1686	Belongs to the peptidase S11 family
OCU28_RS03365	COG0702	epimerase
OCU28_RS03370	COG3383	formate dehydrogenase (NAD+) activity
OCU28_RS03390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OCU28_RS03395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCU28_RS03400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCU28_RS03405	COG1595	DNA-templated transcription, initiation
OCU28_RS03410	COG1132	(ABC) transporter
OCU28_RS03415	COG1132	(ABC) transporter
OCU28_RS03425	COG0786	glutamate:sodium symporter activity
OCU28_RS03445	COG1028	Short-chain dehydrogenase reductase Sdr
OCU28_RS03455	COG1904	glucuronate isomerase
OCU28_RS03510	COG1566	PFAM secretion protein HlyD family protein
OCU28_RS03565	COG1505	serine-type exopeptidase activity
OCU28_RS03575	COG3842	ATPase activity
OCU28_RS03580	COG0395	ABC-type sugar transport system, permease component
OCU28_RS03590	COG1653	transport
OCU28_RS03605	COG4974	Belongs to the 'phage' integrase family
OCU28_RS03625	COG3083	sulfuric ester hydrolase activity
OCU28_RS03630	COG3082	Protein of unknown function (DUF1414)
OCU28_RS03635	COG3081	Nucleoid-associated protein
OCU28_RS03640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OCU28_RS03645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OCU28_RS03650	COG2095	MarC family integral membrane protein
OCU28_RS03655	COG1012	belongs to the aldehyde dehydrogenase family
OCU28_RS03655	COG1454	alcohol dehydrogenase
OCU28_RS03660	COG1028	Short-chain dehydrogenase reductase Sdr
OCU28_RS03670	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OCU28_RS03675	COG2056	Na+-H+ antiporter family
OCU28_RS03680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OCU28_RS03685	COG0346	lactoylglutathione lyase activity
OCU28_RS03725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OCU28_RS03730	COG4660	Part of a membrane complex involved in electron transport
OCU28_RS03735	COG4659	FMN binding
OCU28_RS03740	COG4658	electron transport chain
OCU28_RS03745	COG4656	Part of a membrane complex involved in electron transport
OCU28_RS03750	COG2878	Part of a membrane complex involved in electron transport
OCU28_RS03755	COG4657	Part of a membrane complex involved in electron transport
OCU28_RS03760	COG1902	pentaerythritol trinitrate reductase activity
OCU28_RS03770	COG0556	nucleotide-excision repair
OCU28_RS03775	COG2204	response regulator
OCU28_RS03785	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OCU28_RS03790	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OCU28_RS03795	COG0521	Mo-molybdopterin cofactor biosynthetic process
OCU28_RS03800	COG0315	cyclic pyranopterin monophosphate synthase activity
OCU28_RS03805	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OCU28_RS03810	COG0314	molybdopterin synthase activity
OCU28_RS03820	COG0601	transmembrane transport
OCU28_RS03825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCU28_RS03830	COG0444	Belongs to the ABC transporter superfamily
OCU28_RS03850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCU28_RS03855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCU28_RS03865	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OCU28_RS03880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OCU28_RS03885	COG1522	sequence-specific DNA binding
OCU28_RS03890	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCU28_RS03895	COG1946	Acyl-CoA thioesterase
OCU28_RS03900	COG3126	Type III secretion system lipoprotein chaperone (YscW)
OCU28_RS03935	COG2161	toxin-antitoxin pair type II binding
OCU28_RS03950	COG2207	Transcriptional regulator
OCU28_RS03950	COG3708	Transcriptional regulator
OCU28_RS04000	COG1720	tRNA m6t6A37 methyltransferase activity
OCU28_RS04030	COG1228	amidohydrolase
OCU28_RS04055	COG0513	Belongs to the DEAD box helicase family
OCU28_RS04070	COG4968	Prepilin-type N-terminal cleavage methylation domain
OCU28_RS04075	COG1227	inorganic diphosphatase activity
OCU28_RS04085	COG1882	Formate acetyltransferase
OCU28_RS04095	COG1028	Short-chain dehydrogenase reductase Sdr
OCU28_RS04100	COG4628	conserved protein (DUF2132)
OCU28_RS04110	COG3005	denitrification pathway
OCU28_RS04115	COG0243	molybdopterin cofactor binding
OCU28_RS04120	COG1482	cell wall glycoprotein biosynthetic process
OCU28_RS04125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCU28_RS04125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCU28_RS04125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCU28_RS04130	COG2207	Transcriptional regulator
OCU28_RS04140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCU28_RS04170	COG0653	protein targeting
OCU28_RS04175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCU28_RS04185	COG0513	Belongs to the DEAD box helicase family
OCU28_RS04210	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OCU28_RS04215	COG0583	DNA-binding transcription factor activity
OCU28_RS04220	COG2814	Major facilitator Superfamily
OCU28_RS04250	COG0517	IMP dehydrogenase activity
OCU28_RS04250	COG0617	tRNA 3'-terminal CCA addition
OCU28_RS04250	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OCU28_RS04265	COG0537	adenosine 5'-monophosphoramidase activity
OCU28_RS04285	COG3150	esterase
OCU28_RS04290	COG1252	NADH dehydrogenase
OCU28_RS04305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OCU28_RS04310	COG4591	ABC-type transport system involved in lipoprotein release permease component
OCU28_RS04315	COG1136	(ABC) transporter
OCU28_RS04320	COG4591	ABC-type transport system involved in lipoprotein release permease component
OCU28_RS04330	COG0658	competence protein
OCU28_RS04330	COG2333	competence protein COMEC
OCU28_RS04335	COG1132	(ABC) transporter
OCU28_RS04340	COG1663	tetraacyldisaccharide 4'-kinase activity
OCU28_RS04345	COG2835	tetraacyldisaccharide 4'-kinase activity
OCU28_RS04365	COG0409	Hydrogenase expression formation protein
OCU28_RS04375	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OCU28_RS04380	COG0375	protein maturation
OCU28_RS04390	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
OCU28_RS04405	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OCU28_RS04410	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
OCU28_RS04415	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
OCU28_RS04420	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
OCU28_RS04425	COG0309	Hydrogenase expression formation protein (HypE)
OCU28_RS04435	COG2719	SpoVR family
OCU28_RS04440	COG2718	Belongs to the UPF0229 family
OCU28_RS04445	COG2766	serine protein kinase
OCU28_RS04455	COG3013	Belongs to the UPF0304 family
OCU28_RS04460	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OCU28_RS04465	COG0513	Belongs to the DEAD box helicase family
OCU28_RS04475	COG1882	Formate acetyltransferase
OCU28_RS04490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCU28_RS04500	COG4160	amino acid transport
OCU28_RS04505	COG0708	Exodeoxyribonuclease III
OCU28_RS04525	COG1199	ATP-dependent helicase activity
OCU28_RS04535	COG0297	glycogen (starch) synthase activity
OCU28_RS04545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OCU28_RS04565	COG1187	pseudouridine synthase activity
OCU28_RS04580	COG0531	amino acid
OCU28_RS04590	COG1278	Cold shock
OCU28_RS04595	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OCU28_RS04600	COG0542	response to heat
OCU28_RS04605	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OCU28_RS04615	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OCU28_RS04625	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OCU28_RS04640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OCU28_RS04645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCU28_RS04650	COG2916	Histone family protein nucleoid-structuring protein H-NS
OCU28_RS04655	COG1757	Na H antiporter
OCU28_RS04670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OCU28_RS04675	COG0131	Imidazoleglycerol-phosphate dehydratase
OCU28_RS04675	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OCU28_RS04680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OCU28_RS04685	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OCU28_RS04695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OCU28_RS04695	COG0140	phosphoribosyl-ATP diphosphatase activity
OCU28_RS04705	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OCU28_RS04710	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCU28_RS04715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OCU28_RS04720	COG0215	cysteine-tRNA ligase activity
OCU28_RS04725	COG1435	thymidine kinase activity
OCU28_RS04770	COG0500	methyltransferase
OCU28_RS04775	COG1227	inorganic diphosphatase activity
OCU28_RS04780	COG3152	Membrane
OCU28_RS04785	COG4172	Belongs to the ABC transporter superfamily
OCU28_RS04795	COG4171	peptide transport system, permease
OCU28_RS04800	COG4168	peptide transport system, permease
OCU28_RS04810	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OCU28_RS04815	COG1842	Phage shock protein A
OCU28_RS04830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCU28_RS04835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCU28_RS04845	COG2818	Glycosylase
OCU28_RS04865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCU28_RS04870	COG0626	cystathionine gamma-synthase activity
OCU28_RS04880	COG0564	pseudouridine synthase activity
OCU28_RS04885	COG0116	Belongs to the methyltransferase superfamily
OCU28_RS04885	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OCU28_RS04900	COG2350	Protein conserved in bacteria
OCU28_RS04910	COG2917	probably involved in intracellular septation
OCU28_RS04930	COG0583	DNA-binding transcription factor activity
OCU28_RS04935	COG0159	tryptophan synthase activity
OCU28_RS04940	COG0133	tryptophan synthase activity
OCU28_RS04945	COG0134	indole-3-glycerol-phosphate synthase activity
OCU28_RS04945	COG0135	phosphoribosylanthranilate isomerase activity
OCU28_RS04950	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OCU28_RS04955	COG0512	Glutamine amidotransferase of anthranilate synthase
OCU28_RS04960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OCU28_RS04965	COG0613	PHP domain protein
OCU28_RS04970	COG0009	L-threonylcarbamoyladenylate synthase
OCU28_RS04975	COG1187	pseudouridine synthase activity
OCU28_RS04985	COG1187	pseudouridine synthase activity
OCU28_RS05000	COG1380	Effector of murein hydrolase LrgA
OCU28_RS05005	COG0583	DNA-binding transcription factor activity
OCU28_RS05015	COG0417	DNA replication proofreading
OCU28_RS05020	COG2197	response regulator
OCU28_RS05025	COG0322	excinuclease ABC activity
OCU28_RS05075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCU28_RS05075	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OCU28_RS05075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCU28_RS05080	COG1105	Belongs to the carbohydrate kinase PfkB family
OCU28_RS05085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCU28_RS05085	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCU28_RS05090	COG1609	Transcriptional regulator
OCU28_RS05105	COG0019	diaminopimelate decarboxylase activity
OCU28_RS05110	COG0287	Prephenate dehydrogenase
OCU28_RS05115	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OCU28_RS05120	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OCU28_RS05125	COG1454	alcohol dehydrogenase
OCU28_RS05130	COG0625	glutathione transferase activity
OCU28_RS05135	COG1737	Transcriptional regulator
OCU28_RS05140	COG0076	glutamate decarboxylase activity
OCU28_RS05150	COG2431	L-lysine efflux transmembrane transporter activity
OCU28_RS05155	COG3070	regulator of competence-specific genes
OCU28_RS05160	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OCU28_RS05180	COG0277	FAD linked oxidase domain protein
OCU28_RS05180	COG0247	lactate metabolic process
OCU28_RS05205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OCU28_RS05220	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OCU28_RS05235	COG2897	thiosulfate sulfurtransferase activity
OCU28_RS05260	COG2133	pyrroloquinoline quinone binding
OCU28_RS05265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OCU28_RS05270	COG0072	phenylalanine-tRNA ligase activity
OCU28_RS05270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCU28_RS05275	COG0776	regulation of translation
OCU28_RS05280	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OCU28_RS05285	COG0295	cytidine deaminase activity
OCU28_RS05290	COG1346	cytolysis
OCU28_RS05295	COG1380	Effector of murein hydrolase LrgA
OCU28_RS05300	COG2925	Exonuclease
OCU28_RS05305	COG0303	'Molybdopterin
OCU28_RS05310	COG0746	molybdenum cofactor guanylyltransferase activity
OCU28_RS05315	COG1122	ATPase activity
OCU28_RS05320	COG4662	Binding-protein-dependent transport system inner membrane component
OCU28_RS05330	COG2204	response regulator
OCU28_RS05335	COG3852	Histidine kinase
OCU28_RS05340	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OCU28_RS05370	COG0243	molybdopterin cofactor binding
OCU28_RS05370	COG3383	formate dehydrogenase (NAD+) activity
OCU28_RS05375	COG0437	4 iron, 4 sulfur cluster binding
OCU28_RS05415	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OCU28_RS05440	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OCU28_RS05450	COG0513	Belongs to the DEAD box helicase family
OCU28_RS05455	COG4895	conserved protein (DUF2196)
OCU28_RS05475	COG0629	single-stranded DNA binding
OCU28_RS05480	COG2252	PERMEase
OCU28_RS05485	COG1741	Belongs to the pirin family
OCU28_RS05515	COG0420	3'-5' exonuclease activity
OCU28_RS05520	COG0419	ATPase involved in DNA repair
OCU28_RS05530	COG0826	peptidase U32
OCU28_RS05535	COG0039	L-malate dehydrogenase activity
OCU28_RS05545	COG1028	Short-chain dehydrogenase reductase Sdr
OCU28_RS05550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OCU28_RS05555	COG1793	dna ligase
OCU28_RS05560	COG0534	Mate efflux family protein
OCU28_RS05565	COG0307	riboflavin synthase, alpha
OCU28_RS05575	COG3001	Fructosamine kinase
OCU28_RS05580	COG0791	NLP P60 protein
OCU28_RS05590	COG3148	PFAM DTW domain containing protein
OCU28_RS05595	COG1940	carbohydrate kinase activity
OCU28_RS05620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OCU28_RS05645	COG0589	response to stress
OCU28_RS05650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OCU28_RS05665	COG2217	Heavy metal translocating P-type atpase
OCU28_RS05675	COG2010	Cytochrome c
OCU28_RS05690	COG3278	Belongs to the heme-copper respiratory oxidase family
OCU28_RS05700	COG2807	transmembrane transport
OCU28_RS05710	COG3120	sequence-specific DNA binding
OCU28_RS05715	COG1067	ATP-dependent peptidase activity
OCU28_RS05735	COG0488	(ABC) transporter
OCU28_RS05745	COG0116	Belongs to the methyltransferase superfamily
OCU28_RS05745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OCU28_RS05760	COG2902	Dehydrogenase
OCU28_RS05765	COG0308	aminopeptidase N
OCU28_RS05780	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
OCU28_RS05785	COG1956	GAF domain-containing protein
OCU28_RS05790	COG2995	paraquat-inducible protein a
OCU28_RS05795	COG3008	intermembrane lipid transfer
OCU28_RS05800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OCU28_RS05800	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
OCU28_RS05815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OCU28_RS05820	COG1666	GTP binding
OCU28_RS05825	COG1648	precorrin-2 dehydrogenase activity
OCU28_RS05825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OCU28_RS05830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCU28_RS05835	COG4597	amino acid ABC transporter
OCU28_RS05840	COG0765	amino acid transport
OCU28_RS05845	COG1126	abc transporter atp-binding protein
OCU28_RS05850	COG0670	Belongs to the BI1 family
OCU28_RS05860	COG1254	Belongs to the acylphosphatase family
OCU28_RS05865	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OCU28_RS05890	COG0561	phosphatase activity
OCU28_RS05900	COG1280	lysine exporter protein (LysE YggA)
OCU28_RS05910	COG1115	amino acid carrier protein
OCU28_RS05915	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OCU28_RS05920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCU28_RS05940	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OCU28_RS05965	COG1643	Atp-dependent helicase
OCU28_RS06000	COG0443	Heat shock 70 kDa protein
OCU28_RS06005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCU28_RS06005	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCU28_RS06055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCU28_RS06070	COG3106	COG3106 Predicted ATPase
OCU28_RS06085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OCU28_RS06090	COG0494	nUDIX hydrolase
OCU28_RS06095	COG0017	Asparaginyl-tRNA synthetase
OCU28_RS06100	COG1448	Aminotransferase
OCU28_RS06120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OCU28_RS06135	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OCU28_RS06145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCU28_RS06150	COG3108	Peptidase M15
OCU28_RS06155	COG2989	Protein conserved in bacteria
OCU28_RS06170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCU28_RS06175	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OCU28_RS06180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OCU28_RS06185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OCU28_RS06195	COG1546	Belongs to the CinA family
OCU28_RS06195	COG1058	Belongs to the CinA family
OCU28_RS06205	COG1960	acyl-CoA dehydrogenase activity
OCU28_RS06210	COG1309	transcriptional regulator
OCU28_RS06215	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OCU28_RS06230	COG1136	(ABC) transporter
OCU28_RS06235	COG0702	epimerase
OCU28_RS06245	COG2814	Major facilitator Superfamily
OCU28_RS06255	COG1061	Type III restriction enzyme res subunit
OCU28_RS06260	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OCU28_RS06265	COG0328	RNA-DNA hybrid ribonuclease activity
OCU28_RS06300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OCU28_RS06305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCU28_RS06325	COG3313	Fe-S protein
OCU28_RS06335	COG0281	malic enzyme
OCU28_RS06340	COG2949	membrane
OCU28_RS06345	COG0492	ferredoxin-NADP+ reductase activity
OCU28_RS06350	COG4988	ABC transporter
OCU28_RS06355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OCU28_RS06375	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OCU28_RS06385	COG4191	Histidine kinase
OCU28_RS06385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCU28_RS06445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCU28_RS06450	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
OCU28_RS06455	COG3104	oligopeptide transport
OCU28_RS06470	COG2195	Cleaves the N-terminal amino acid of tripeptides
OCU28_RS06490	COG4628	conserved protein (DUF2132)
OCU28_RS06505	COG1272	protein, Hemolysin III
OCU28_RS06535	COG3639	organic phosphonate transmembrane transporter activity
OCU28_RS06540	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
OCU28_RS06555	COG1263	PTS System
OCU28_RS06555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCU28_RS06575	COG2217	Heavy metal translocating P-type atpase
OCU28_RS06580	COG0789	Transcriptional regulator
OCU28_RS06600	COG2358	TRAP transporter, solute receptor (TAXI family
OCU28_RS06615	COG4160	amino acid transport
OCU28_RS06620	COG4215	(ABC) transporter
OCU28_RS06625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCU28_RS06630	COG1126	abc transporter atp-binding protein
OCU28_RS06640	COG3033	Beta-eliminating lyase
OCU28_RS06645	COG0814	amino acid
OCU28_RS06670	COG0514	ATP-dependent DNA helicase (RecQ)
OCU28_RS06675	COG1054	Belongs to the UPF0176 family
OCU28_RS06685	COG0318	PFAM AMP-dependent synthetase and ligase
OCU28_RS06690	COG0583	DNA-binding transcription factor activity
OCU28_RS06735	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OCU28_RS06740	COG0387	Pfam Sodium calcium exchanger
OCU28_RS06750	COG2239	Acts as a magnesium transporter
OCU28_RS06770	COG0583	DNA-binding transcription factor activity
OCU28_RS06775	COG0668	transmembrane transport
OCU28_RS06785	COG5433	transposase activity
OCU28_RS06825	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OCU28_RS06830	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
OCU28_RS06835	COG2885	chlorophyll binding
OCU28_RS06840	COG0823	Involved in the tonB-independent uptake of proteins
OCU28_RS06855	COG0811	peptide transport
OCU28_RS06860	COG0824	Thioesterase
OCU28_RS06865	COG4890	Cyd operon protein YbgT
OCU28_RS06870	COG1294	oxidase, subunit
OCU28_RS06875	COG1271	oxidase subunit
OCU28_RS06880	COG2255	four-way junction helicase activity
OCU28_RS06885	COG0632	four-way junction helicase activity
OCU28_RS06900	COG4106	trans-aconitate 2-methyltransferase activity
OCU28_RS06905	COG0243	molybdopterin cofactor binding
OCU28_RS06910	COG3005	denitrification pathway
OCU28_RS06915	COG4459	periplasmic nitrate reductase
OCU28_RS06935	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
OCU28_RS06940	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
OCU28_RS06945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCU28_RS06950	COG1434	Gram-negative-bacterium-type cell wall biogenesis
OCU28_RS06955	COG3381	protein complex oligomerization
OCU28_RS06960	COG1609	Transcriptional regulator
OCU28_RS06995	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OCU28_RS07010	COG0300	oxidoreductase activity
OCU28_RS07020	COG0501	Belongs to the peptidase M48B family
OCU28_RS07030	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OCU28_RS07035	COG2226	methyltransferase
OCU28_RS07040	COG0156	8-amino-7-oxononanoate synthase activity
OCU28_RS07045	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OCU28_RS07065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OCU28_RS07080	COG1522	sequence-specific DNA binding
OCU28_RS07085	COG0686	Belongs to the AlaDH PNT family
OCU28_RS07115	COG0700	Nucleoside recognition
OCU28_RS07120	COG3366	ferrous iron transmembrane transporter activity
OCU28_RS07125	COG0284	orotidine-5'-phosphate decarboxylase activity
OCU28_RS07130	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
OCU28_RS07135	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
OCU28_RS07145	COG0539	negative regulation of cytoplasmic translation
OCU28_RS07155	COG0616	signal peptide processing
OCU28_RS07160	COG1028	Short-chain dehydrogenase reductase Sdr
OCU28_RS07165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OCU28_RS07170	COG0778	Nitroreductase
OCU28_RS07175	COG0446	pyridine nucleotide-disulphide oxidoreductase
OCU28_RS07175	COG1902	pentaerythritol trinitrate reductase activity
OCU28_RS07180	COG0616	signal peptide processing
OCU28_RS07185	COG0252	asparaginase activity
OCU28_RS07190	COG3139	Protein of unknown function (DUF1315)
OCU28_RS07195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCU28_RS07200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OCU28_RS07210	COG2226	methyltransferase
OCU28_RS07240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OCU28_RS07245	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OCU28_RS07260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OCU28_RS07265	COG2832	Protein of unknown function (DUF454)
OCU28_RS07270	COG0745	RESPONSE REGULATOR receiver
OCU28_RS07275	COG0583	DNA-binding transcription factor activity
OCU28_RS07280	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OCU28_RS07285	COG1286	toxin biosynthetic process
OCU28_RS07290	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
OCU28_RS07295	COG0285	dihydrofolate synthase activity
OCU28_RS07300	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OCU28_RS07305	COG0101	tRNA pseudouridine synthase activity
OCU28_RS07315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OCU28_RS07320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OCU28_RS07325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OCU28_RS07330	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
OCU28_RS07330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OCU28_RS07345	COG3101	peptidyl-lysine hydroxylation
OCU28_RS07360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OCU28_RS07365	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OCU28_RS07370	COG2890	protein-(glutamine-N5) methyltransferase activity
OCU28_RS07375	COG2840	Smr protein MutS2
OCU28_RS07380	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
OCU28_RS07385	COG2062	phosphohistidine phosphatase, SixA
OCU28_RS07400	COG1024	Enoyl-CoA hydratase
OCU28_RS07400	COG1250	3-hydroxyacyl-CoA dehydrogenase
OCU28_RS07405	COG0183	Belongs to the thiolase family
OCU28_RS07420	COG2067	long-chain fatty acid transport protein
OCU28_RS07430	COG2853	Lipoprotein
OCU28_RS07435	COG4235	cytochrome complex assembly
OCU28_RS07445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OCU28_RS07450	COG1138	Cytochrome C-type biogenesis protein
OCU28_RS07465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OCU28_RS07470	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OCU28_RS07475	COG4133	protoheme IX ABC transporter activity
OCU28_RS07480	COG0583	DNA-binding transcription factor activity
OCU28_RS07490	COG2885	chlorophyll binding
OCU28_RS07530	COG0455	bacterial-type flagellum organization
OCU28_RS07540	COG4964	Belongs to the GSP D family
OCU28_RS07575	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OCU28_RS07580	COG1349	DNA-binding transcription factor activity
OCU28_RS07585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OCU28_RS07605	COG2095	MarC family integral membrane protein
OCU28_RS07610	COG1902	pentaerythritol trinitrate reductase activity
OCU28_RS07620	COG3069	C4-dicarboxylate transmembrane transporter activity
OCU28_RS07630	COG2982	Protein involved in outer membrane biogenesis
OCU28_RS07635	COG0572	uridine kinase
OCU28_RS07640	COG0489	protein tyrosine kinase activity
OCU28_RS07645	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCU28_RS07645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCU28_RS07650	COG1940	carbohydrate kinase activity
OCU28_RS07655	COG4667	esterase of the alpha-beta hydrolase superfamily
OCU28_RS07665	COG0733	neurotransmitter:sodium symporter activity
OCU28_RS07680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCU28_RS07680	COG1263	PTS System
OCU28_RS07685	COG0084	hydrolase, TatD family'
OCU28_RS07690	COG0470	DNA polymerase III
OCU28_RS07695	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OCU28_RS07700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OCU28_RS07730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OCU28_RS07740	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OCU28_RS07745	COG1399	metal-binding, possibly nucleic acid-binding protein
OCU28_RS07750	COG0424	maF-like protein
OCU28_RS07755	COG0564	pseudouridine synthase activity
OCU28_RS07760	COG1530	ribonuclease E activity
OCU28_RS07765	COG0659	secondary active sulfate transmembrane transporter activity
OCU28_RS07790	COG0667	Aldo Keto reductase
OCU28_RS07805	COG0697	spore germination
OCU28_RS07855	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OCU28_RS07860	COG2951	lytic endotransglycosylase activity
OCU28_RS07865	COG3100	YcgL domain-containing protein
OCU28_RS07870	COG0850	regulation of cytokinetic process
OCU28_RS07875	COG2894	cell division
OCU28_RS07880	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OCU28_RS07885	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
OCU28_RS07890	COG0318	PFAM AMP-dependent synthetase and ligase
OCU28_RS07895	COG0596	Alpha beta hydrolase
OCU28_RS07900	COG3065	identical protein binding
OCU28_RS07905	COG1214	PFAM Peptidase M22, glycoprotease
OCU28_RS07910	COG1199	ATP-dependent helicase activity
OCU28_RS07915	COG0788	formyltetrahydrofolate deformylase activity
OCU28_RS07920	COG3102	Protein conserved in bacteria
OCU28_RS07925	COG0018	arginyl-trna synthetase
OCU28_RS07930	COG0733	neurotransmitter:sodium symporter activity
OCU28_RS07950	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OCU28_RS07960	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
OCU28_RS07965	COG1121	(ABC) transporter
OCU28_RS07970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OCU28_RS07985	COG0508	dehydrogenase complex catalyzes the overall conversion of
OCU28_RS07990	COG0567	Dehydrogenase, E1 component
OCU28_RS07995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OCU28_RS08000	COG1053	succinate dehydrogenase
OCU28_RS08005	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OCU28_RS08020	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OCU28_RS08035	COG0033	Phosphoglucomutase
OCU28_RS08040	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
OCU28_RS08045	COG0596	Alpha beta hydrolase
OCU28_RS08065	COG0735	belongs to the Fur family
OCU28_RS08080	COG1263	PTS System
OCU28_RS08080	COG2190	(PTS) system
OCU28_RS08080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCU28_RS08085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OCU28_RS08090	COG1940	carbohydrate kinase activity
OCU28_RS08090	COG1846	Transcriptional regulator
OCU28_RS08095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OCU28_RS08095	COG4651	solute:proton antiporter activity
OCU28_RS08100	COG3706	GGDEF domain
OCU28_RS08105	COG0367	asparagine synthase
OCU28_RS08110	COG0250	Participates in transcription elongation, termination and antitermination
OCU28_RS08115	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OCU28_RS08125	COG0326	Molecular chaperone. Has ATPase activity
OCU28_RS08130	COG3710	Transcriptional regulator
OCU28_RS08140	COG0622	Phosphoesterase
OCU28_RS08145	COG1090	epimerase
OCU28_RS08150	COG3118	belongs to the thioredoxin family
OCU28_RS08155	COG0330	HflC and HflK could
OCU28_RS08165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OCU28_RS08170	COG3115	cell septum assembly
OCU28_RS08175	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
OCU28_RS08185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCU28_RS08190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OCU28_RS08195	COG2190	(PTS) system
OCU28_RS08200	COG2837	iron assimilation
OCU28_RS08220	COG1393	Belongs to the ArsC family
OCU28_RS08230	COG1876	peptidase activity
OCU28_RS08245	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
OCU28_RS08250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OCU28_RS08255	COG2716	regulation of RNA biosynthetic process
OCU28_RS08260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OCU28_RS08275	COG4783	chaperone-mediated protein folding
OCU28_RS08280	COG1393	Belongs to the ArsC family
OCU28_RS08295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OCU28_RS08300	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OCU28_RS08305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OCU28_RS08315	COG0121	glutamine amidotransferase
OCU28_RS08320	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OCU28_RS08330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OCU28_RS08335	COG0328	RNA-DNA hybrid ribonuclease activity
OCU28_RS08340	COG2226	methyltransferase
OCU28_RS08350	COG0741	lytic transglycosylase activity
OCU28_RS08350	COG1388	LysM domain
OCU28_RS08370	COG0037	tRNA processing
OCU28_RS08375	COG0825	malonyl-CoA metabolic process
OCU28_RS08380	COG0587	DNA-directed DNA polymerase activity
OCU28_RS08385	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OCU28_RS08395	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCU28_RS08400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OCU28_RS08405	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCU28_RS08410	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
OCU28_RS08415	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCU28_RS08420	COG0750	zinc metalloprotease
OCU28_RS08430	COG0575	Belongs to the CDS family
OCU28_RS08435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OCU28_RS08440	COG0233	cytoplasmic translational termination
OCU28_RS08460	COG0024	Methionine aminopeptidase
OCU28_RS08465	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OCU28_RS08470	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
OCU28_RS08480	COG0564	pseudouridine synthase activity
OCU28_RS08485	COG3098	single-species biofilm formation
OCU28_RS08505	COG1671	Belongs to the UPF0178 family
OCU28_RS08510	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
OCU28_RS08520	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OCU28_RS08520	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OCU28_RS08530	COG1611	Belongs to the LOG family
OCU28_RS08535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCU28_RS08540	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
OCU28_RS08545	COG0583	DNA-binding transcription factor activity
OCU28_RS08550	COG0301	tRNA thio-modification
OCU28_RS08550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OCU28_RS08555	COG1722	exodeoxyribonuclease VII activity
OCU28_RS08560	COG0142	geranyltranstransferase activity
OCU28_RS08565	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OCU28_RS08570	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OCU28_RS08575	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OCU28_RS08580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OCU28_RS08600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OCU28_RS08600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OCU28_RS08610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OCU28_RS08625	COG1073	alpha beta
OCU28_RS08630	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
OCU28_RS08635	COG2252	PERMEase
OCU28_RS08640	COG2195	Cleaves the N-terminal amino acid of tripeptides
OCU28_RS08650	COG0047	phosphoribosylformylglycinamidine synthase activity
OCU28_RS08650	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OCU28_RS08655	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OCU28_RS08670	COG0583	DNA-binding transcription factor activity
OCU28_RS08685	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OCU28_RS08710	COG0484	heat shock protein binding
OCU28_RS08715	COG0443	Heat shock 70 kDa protein
OCU28_RS08720	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OCU28_RS08730	COG0497	DNA recombination
OCU28_RS08735	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCU28_RS08740	COG2914	Belongs to the UPF0125 (RnfH) family
OCU28_RS08745	COG2867	negative regulation of translational initiation
OCU28_RS08750	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OCU28_RS08760	COG0582	viral genome integration into host DNA
OCU28_RS08765	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OCU28_RS08775	COG0514	ATP-dependent DNA helicase (RecQ)
OCU28_RS08795	COG1396	sequence-specific DNA binding
OCU28_RS08800	COG3550	peptidyl-serine autophosphorylation
OCU28_RS08810	COG2137	regulation of response to DNA damage stimulus
OCU28_RS08815	COG0251	oxidation-reduction process
OCU28_RS08835	COG3181	Tripartite tricarboxylate transporter family receptor
OCU28_RS08845	COG0798	PFAM Bile acid sodium symporter
OCU28_RS08855	COG0583	DNA-binding transcription factor activity
OCU28_RS08860	COG2116	formate transmembrane transporter activity
OCU28_RS08865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OCU28_RS08870	COG4136	ATPase activity
OCU28_RS08875	COG4135	transport system, permease component
OCU28_RS08880	COG4134	Bacterial extracellular solute-binding protein
OCU28_RS08890	COG3122	Protein conserved in bacteria
OCU28_RS08900	COG0516	GMP reductase activity
OCU28_RS08900	COG0517	IMP dehydrogenase activity
OCU28_RS08905	COG1570	exodeoxyribonuclease VII activity
OCU28_RS08915	COG1160	GTP binding
OCU28_RS08920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCU28_RS08925	COG2976	Protein conserved in bacteria
OCU28_RS08930	COG0124	histidyl-tRNA synthetase
OCU28_RS08935	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OCU28_RS08940	COG1426	Protein conserved in bacteria
OCU28_RS08955	COG0105	UTP biosynthetic process
OCU28_RS08965	COG2975	iron-sulfur cluster assembly
OCU28_RS08970	COG0633	Ferredoxin
OCU28_RS08985	COG0316	Belongs to the HesB IscA family
OCU28_RS08990	COG0822	iron-sulfur transferase activity
OCU28_RS09000	COG1959	2 iron, 2 sulfur cluster binding
OCU28_RS09005	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
OCU28_RS09010	COG0483	inositol monophosphate 1-phosphatase activity
OCU28_RS09015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OCU28_RS09020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OCU28_RS09025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OCU28_RS09035	COG1534	Rna-binding protein
OCU28_RS09040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OCU28_RS09055	COG2027	D-alanyl-D-alanine carboxypeptidase
OCU28_RS09065	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OCU28_RS09070	COG0739	heme binding
OCU28_RS09085	COG0316	Belongs to the HesB IscA family
OCU28_RS09090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OCU28_RS09095	COG0628	permease
OCU28_RS09105	COG0784	Response regulator, receiver
OCU28_RS09105	COG2198	Histidine kinase
OCU28_RS09105	COG2205	protein histidine kinase activity
OCU28_RS09115	COG0747	negative chemotaxis
OCU28_RS09130	COG0444	Belongs to the ABC transporter superfamily
OCU28_RS09135	COG4608	Belongs to the ABC transporter superfamily
OCU28_RS09145	COG2971	BadF BadG BcrA BcrD
OCU28_RS09155	COG3842	ATPase activity
OCU28_RS09170	COG0004	ammonium transporteR
OCU28_RS09180	COG3112	Uncharacterised protein family (UPF0231)
OCU28_RS09185	COG1049	propionate catabolic process, 2-methylcitrate cycle
OCU28_RS09190	COG1752	Esterase of the alpha-beta hydrolase superfamily
OCU28_RS09195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OCU28_RS09200	COG1643	Atp-dependent helicase
OCU28_RS09205	COG1489	DNA binding
OCU28_RS09210	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OCU28_RS09215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OCU28_RS09225	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OCU28_RS09230	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OCU28_RS09235	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OCU28_RS09240	COG0842	Transport permease protein
OCU28_RS09245	COG1131	(ABC) transporter
OCU28_RS09250	COG0288	reversible hydration of carbon dioxide
OCU28_RS09260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCU28_RS09265	COG0508	dehydrogenase complex catalyzes the overall conversion of
OCU28_RS09270	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OCU28_RS09275	COG2186	Transcriptional regulator
OCU28_RS09285	COG0157	Belongs to the NadC ModD family
OCU28_RS09295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OCU28_RS09300	COG1459	type II secretion system
OCU28_RS09310	COG0237	dephospho-CoA kinase activity
OCU28_RS09315	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
OCU28_RS09320	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OCU28_RS09325	COG0335	large ribosomal subunit rRNA binding
OCU28_RS09330	COG0336	Belongs to the RNA methyltransferase TrmD family
OCU28_RS09340	COG0228	four-way junction DNA binding
OCU28_RS09345	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OCU28_RS09350	COG4137	Cytochrome C assembly protein
OCU28_RS09355	COG4536	flavin adenine dinucleotide binding
OCU28_RS09360	COG1854	S-ribosylhomocysteine lyase activity
OCU28_RS09370	COG0612	Peptidase, M16
OCU28_RS09375	COG1238	metal cluster binding
OCU28_RS09380	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
OCU28_RS09385	COG0511	ligase activity, forming carbon-carbon bonds
OCU28_RS09385	COG5016	pyruvate
OCU28_RS09390	COG3630	sodium ion export across plasma membrane
OCU28_RS09440	COG0527	aspartate kinase activity
OCU28_RS09450	COG2137	regulation of response to DNA damage stimulus
OCU28_RS09455	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OCU28_RS09460	COG1546	Belongs to the CinA family
OCU28_RS09470	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OCU28_RS09475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OCU28_RS09485	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OCU28_RS09490	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OCU28_RS09495	COG0585	pseudouridine synthase activity
OCU28_RS09500	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OCU28_RS09505	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OCU28_RS09515	COG0148	phosphopyruvate hydratase activity
OCU28_RS09525	COG3956	TIGRFAM MazG family protein
OCU28_RS09530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OCU28_RS09535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OCU28_RS09550	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OCU28_RS09555	COG1381	Involved in DNA repair and RecF pathway recombination
OCU28_RS09560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OCU28_RS09565	COG0571	ribonuclease III activity
OCU28_RS09575	COG0481	GTPase activity
OCU28_RS09590	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
OCU28_RS09595	COG1595	DNA-templated transcription, initiation
OCU28_RS09600	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OCU28_RS09610	COG0354	folic acid binding
OCU28_RS09620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OCU28_RS09625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OCU28_RS09630	COG3079	Belongs to the UPF0149 family
OCU28_RS09635	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OCU28_RS09645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OCU28_RS09650	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OCU28_RS09655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OCU28_RS09675	COG0668	transmembrane transport
OCU28_RS09680	COG0191	fructose-bisphosphate aldolase activity
OCU28_RS09685	COG0126	phosphoglycerate kinase activity
OCU28_RS09705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OCU28_RS09710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OCU28_RS09720	COG3091	SprT-like family
OCU28_RS09725	COG2356	endonuclease I
OCU28_RS09730	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OCU28_RS09735	COG0189	ligase activity
OCU28_RS09740	COG1678	Uncharacterized ACR, COG1678
OCU28_RS09745	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OCU28_RS09760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OCU28_RS09775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OCU28_RS09780	COG0762	integral membrane protein
OCU28_RS09790	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OCU28_RS09795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OCU28_RS09810	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OCU28_RS09815	COG1194	a g-specific adenine glycosylase
OCU28_RS09820	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
OCU28_RS09875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OCU28_RS09880	COG2213	PTS system mannitol-specific
OCU28_RS09880	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCU28_RS09885	COG0246	Mannitol dehydrogenase
OCU28_RS09890	COG3722	fumarate hydratase activity
OCU28_RS09900	COG1349	DNA-binding transcription factor activity
OCU28_RS09905	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OCU28_RS09910	COG0004	ammonium transporteR
OCU28_RS09920	COG0251	oxidation-reduction process
OCU28_RS09940	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OCU28_RS09960	COG0795	lipopolysaccharide-transporting ATPase activity
OCU28_RS09965	COG0795	lipopolysaccharide-transporting ATPase activity
OCU28_RS09970	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OCU28_RS09980	COG0525	valine-tRNA ligase activity
OCU28_RS10000	COG0540	Belongs to the ATCase OTCase family
OCU28_RS10010	COG0251	oxidation-reduction process
OCU28_RS10015	COG0204	Acyl-transferase
OCU28_RS10020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OCU28_RS10025	COG5007	Belongs to the BolA IbaG family
OCU28_RS10030	COG3113	response to antibiotic
OCU28_RS10035	COG2854	intermembrane phospholipid transfer
OCU28_RS10040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OCU28_RS10045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OCU28_RS10050	COG1127	ABC transporter
OCU28_RS10060	COG0517	IMP dehydrogenase activity
OCU28_RS10060	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OCU28_RS10065	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OCU28_RS10080	COG1137	ATPase activity
OCU28_RS10095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCU28_RS10100	COG1660	Displays ATPase and GTPase activities
OCU28_RS10105	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCU28_RS10110	COG2239	Acts as a magnesium transporter
OCU28_RS10115	COG0312	modulator of DNA gyrase
OCU28_RS10125	COG0312	modulator of DNA gyrase
OCU28_RS10130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OCU28_RS10135	COG3164	Protein of unknown function
OCU28_RS10145	COG0424	maF-like protein
OCU28_RS10150	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OCU28_RS10155	COG1792	Involved in formation and maintenance of cell shape
OCU28_RS10160	COG1077	Cell shape determining protein MreB Mrl
OCU28_RS10190	COG2165	general secretion pathway protein
OCU28_RS10195	COG4969	Belongs to the N-Me-Phe pilin family
OCU28_RS10200	COG2165	general secretion pathway protein
OCU28_RS10210	COG1459	type II secretion system
OCU28_RS10215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OCU28_RS10225	COG3267	Type II secretory pathway component ExeA
OCU28_RS10225	COG3409	Peptidoglycan-binding domain 1 protein
OCU28_RS10250	COG2199	diguanylate cyclase activity
OCU28_RS10250	COG2200	EAL domain
OCU28_RS10270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OCU28_RS10280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OCU28_RS10285	COG0527	aspartate kinase activity
OCU28_RS10290	COG0646	methionine synthase
OCU28_RS10290	COG1410	methionine synthase
OCU28_RS10385	COG0175	sulfate reduction
OCU28_RS10390	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OCU28_RS10395	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OCU28_RS10415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OCU28_RS10420	COG1464	Belongs to the NlpA lipoprotein family
OCU28_RS10430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OCU28_RS10455	COG2965	DNA replication, synthesis of RNA primer
OCU28_RS10460	COG0360	Binds together with S18 to 16S ribosomal RNA
OCU28_RS10465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OCU28_RS10470	COG0557	exoribonuclease II activity
OCU28_RS10475	COG1959	2 iron, 2 sulfur cluster binding
OCU28_RS10480	COG1017	nitric oxide dioxygenase activity
OCU28_RS10480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OCU28_RS10485	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OCU28_RS10490	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
OCU28_RS10495	COG0330	HflC and HflK could
OCU28_RS10500	COG0330	HflC and HflK could
OCU28_RS10505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OCU28_RS10515	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OCU28_RS10520	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OCU28_RS10525	COG0860	N-Acetylmuramoyl-L-alanine amidase
OCU28_RS10530	COG0802	atpase or kinase
OCU28_RS10535	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OCU28_RS10575	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OCU28_RS10580	COG1162	GTPase activity
OCU28_RS10585	COG0688	phosphatidylethanolamine metabolic process
OCU28_RS10595	COG1575	Belongs to the MenA family. Type 1 subfamily
OCU28_RS10600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OCU28_RS10605	COG0471	metal ion transport
OCU28_RS10605	COG0490	domain, Protein
OCU28_RS10620	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OCU28_RS10625	COG1053	succinate dehydrogenase
OCU28_RS10630	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OCU28_RS10635	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
OCU28_RS10640	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
OCU28_RS10645	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OCU28_RS10650	COG1509	lysine 2,3-aminomutase activity
OCU28_RS10660	COG0488	(ABC) transporter
OCU28_RS10665	COG1119	ATPase activity
OCU28_RS10680	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OCU28_RS10685	COG0534	Mate efflux family protein
OCU28_RS10690	COG1045	serine acetyltransferase
OCU28_RS10695	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OCU28_RS10700	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OCU28_RS10705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OCU28_RS10710	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OCU28_RS10715	COG4942	peptidase
OCU28_RS10725	COG1494	fructose-1,6-bisphosphatase
OCU28_RS10730	COG3152	Membrane
OCU28_RS10765	COG0745	RESPONSE REGULATOR receiver
OCU28_RS10770	COG2205	protein histidine kinase activity
OCU28_RS10775	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OCU28_RS10780	COG3030	protein affecting phage T7 exclusion by the F plasmid
OCU28_RS10785	COG1027	Aspartate ammonia-lyase
OCU28_RS10790	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
OCU28_RS10810	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCU28_RS10815	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OCU28_RS10820	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OCU28_RS10835	COG0784	Response regulator, receiver
OCU28_RS10835	COG2205	protein histidine kinase activity
OCU28_RS10840	COG2814	Major facilitator Superfamily
OCU28_RS10855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OCU28_RS10860	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OCU28_RS10865	COG0511	ligase activity, forming carbon-carbon bonds
OCU28_RS10870	COG0439	Biotin carboxylase
OCU28_RS10885	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OCU28_RS10925	COG0789	Transcriptional regulator
OCU28_RS10930	COG0138	bifunctional purine biosynthesis protein purh
OCU28_RS10935	COG0151	Belongs to the GarS family
OCU28_RS10950	COG1253	flavin adenine dinucleotide binding
OCU28_RS10960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OCU28_RS10970	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OCU28_RS10975	COG1561	YicC-like family, N-terminal region
OCU28_RS11000	COG0653	protein targeting
OCU28_RS11015	COG0194	GDP metabolic process
OCU28_RS11020	COG1758	RNA polymerase activity
OCU28_RS11025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OCU28_RS11030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OCU28_RS11035	COG2003	Belongs to the UPF0758 family
OCU28_RS11045	COG0756	dUTP diphosphatase activity
OCU28_RS11050	COG1309	transcriptional regulator
OCU28_RS11055	COG1560	Kdo2-lipid A biosynthetic process
OCU28_RS11065	COG2816	NAD+ diphosphatase activity
OCU28_RS11070	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
OCU28_RS11075	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OCU28_RS11095	COG0081	regulation of translation
OCU28_RS11105	COG0250	Participates in transcription elongation, termination and antitermination
OCU28_RS11110	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OCU28_RS11115	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OCU28_RS11140	COG1072	(Pantothenic acid kinase))
OCU28_RS11150	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OCU28_RS11160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OCU28_RS11215	COG0724	RNA recognition motif
OCU28_RS11220	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OCU28_RS11225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OCU28_RS11235	COG1309	transcriptional regulator
OCU28_RS11240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCU28_RS11245	COG0534	Mate efflux family protein
OCU28_RS11255	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OCU28_RS11260	COG2937	Belongs to the GPAT DAPAT family
OCU28_RS11265	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OCU28_RS11270	COG3161	chorismate lyase activity
OCU28_RS11275	COG0705	Rhomboid family
OCU28_RS11280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OCU28_RS11285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OCU28_RS11290	COG2177	Part of the ABC transporter FtsEX involved in
OCU28_RS11295	COG2884	Cell division ATP-binding protein ftsE
OCU28_RS11300	COG0552	protein localization to endoplasmic reticulum
OCU28_RS11305	COG0742	ribosomal rna small subunit methyltransferase
OCU28_RS11350	COG1309	transcriptional regulator
OCU28_RS11355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCU28_RS11360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCU28_RS11365	COG2960	long-chain fatty acid transporting porin activity
OCU28_RS11370	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OCU28_RS11375	COG0583	DNA-binding transcription factor activity
OCU28_RS11430	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OCU28_RS11445	COG3118	belongs to the thioredoxin family
OCU28_RS11450	COG0513	Belongs to the DEAD box helicase family
OCU28_RS11455	COG0248	Ppx GppA phosphatase
OCU28_RS11460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OCU28_RS11465	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OCU28_RS11475	COG0514	ATP-dependent DNA helicase (RecQ)
OCU28_RS11480	COG2962	Rard protein
OCU28_RS11485	COG1280	lysine exporter protein (LysE YggA)
OCU28_RS11490	COG0405	Gamma-glutamyltransferase
OCU28_RS11495	COG0210	DNA helicase
OCU28_RS11525	COG0006	proline dipeptidase activity
OCU28_RS11535	COG2022	thiamine diphosphate biosynthetic process
OCU28_RS11545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OCU28_RS11585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OCU28_RS11595	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OCU28_RS11600	COG0408	coproporphyrinogen oxidase activity
OCU28_RS11605	COG0009	L-threonylcarbamoyladenylate synthase
OCU28_RS11610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OCU28_RS11615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OCU28_RS11620	COG0551	DNA topoisomerase type I activity
OCU28_RS11625	COG2922	Belongs to the Smg family
OCU28_RS11630	COG0758	DNA mediated transformation
OCU28_RS11635	COG0242	peptide deformylase activity
OCU28_RS11645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OCU28_RS11645	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OCU28_RS11650	COG0569	domain protein
OCU28_RS11655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OCU28_RS11665	COG0697	spore germination
OCU28_RS11670	COG4326	sporulation control protein
OCU28_RS11675	COG3084	Protein conserved in bacteria
OCU28_RS11685	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OCU28_RS11690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OCU28_RS11695	COG0606	chelatase, subunit chli
OCU28_RS11705	COG3978	acetolactate synthase activity
OCU28_RS11710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OCU28_RS11715	COG0129	dihydroxy-acid dehydratase activity
OCU28_RS11725	COG0583	DNA-binding transcription factor activity
OCU28_RS11730	COG2814	Major facilitator Superfamily
OCU28_RS11735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCU28_RS11740	COG0765	amino acid transport
OCU28_RS11750	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OCU28_RS11760	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OCU28_RS11765	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OCU28_RS11770	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OCU28_RS11775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OCU28_RS11790	COG3312	ion transport
OCU28_RS11795	COG1475	DNA binding
OCU28_RS11800	COG1192	Involved in chromosome partitioning
OCU28_RS11805	COG0357	Ribosomal RNA small subunit methyltransferase G
OCU28_RS11810	COG0445	tRNA wobble uridine modification
OCU28_RS11815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OCU28_RS11820	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OCU28_RS11825	COG0706	membrane insertase activity
OCU28_RS11830	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OCU28_RS11845	COG1126	abc transporter atp-binding protein
OCU28_RS11880	COG0217	transcriptional regulatory protein
OCU28_RS11885	COG2084	Dehydrogenase
OCU28_RS11890	COG0739	heme binding
OCU28_RS11910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCU28_RS11925	COG3300	MHYT domain
OCU28_RS11925	COG5001	Diguanylate cyclase
OCU28_RS11945	COG0569	domain protein
OCU28_RS11950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OCU28_RS11960	COG2999	glutathione oxidoreductase activity
OCU28_RS11970	COG1278	Cold shock
OCU28_RS11980	COG2814	Major facilitator Superfamily
OCU28_RS11995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OCU28_RS12005	COG0745	RESPONSE REGULATOR receiver
OCU28_RS12010	COG5002	protein histidine kinase activity
OCU28_RS12015	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OCU28_RS12040	COG0589	response to stress
OCU28_RS12050	COG0534	Mate efflux family protein
OCU28_RS12055	COG0604	alcohol dehydrogenase
OCU28_RS12100	COG1438	arginine binding
OCU28_RS12105	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OCU28_RS12120	COG1288	antiporter activity
OCU28_RS12145	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OCU28_RS12155	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OCU28_RS12165	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OCU28_RS12195	COG2759	Belongs to the formate--tetrahydrofolate ligase family
OCU28_RS12225	COG2188	Transcriptional regulator
OCU28_RS12240	COG1132	(ABC) transporter
OCU28_RS12260	COG1760	l-serine dehydratase
OCU28_RS12280	COG0529	Catalyzes the synthesis of activated sulfate
OCU28_RS12285	COG0471	metal ion transport
OCU28_RS12285	COG3273	potassium ion transport
OCU28_RS12290	COG2895	sulfate adenylyltransferase (ATP) activity
OCU28_RS12295	COG0175	sulfate reduction
OCU28_RS12300	COG1596	polysaccharide export
OCU28_RS12315	COG0489	protein tyrosine kinase activity
OCU28_RS12315	COG3206	protein involved in exopolysaccharide biosynthesis
OCU28_RS12365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OCU28_RS12400	COG3290	protein histidine kinase activity
OCU28_RS12410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OCU28_RS12415	COG1086	Polysaccharide biosynthesis protein
OCU28_RS12420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OCU28_RS12425	COG1083	cytidylyl-transferase
OCU28_RS12435	COG2089	acid synthase
OCU28_RS12450	COG0438	transferase activity, transferring glycosyl groups
OCU28_RS12475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OCU28_RS12480	COG2909	trisaccharide binding
OCU28_RS12485	COG0058	SHG alpha-glucan phosphorylase activity
OCU28_RS12490	COG1640	4-alpha-glucanotransferase
OCU28_RS12495	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OCU28_RS12500	COG3788	relative of glutathione S-transferase, MAPEG superfamily
OCU28_RS12530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCU28_RS12540	COG0602	queuosine metabolic process
OCU28_RS12550	COG0366	Alpha amylase catalytic
OCU28_RS12555	COG1162	GTPase activity
OCU28_RS12565	COG1999	signal sequence binding
OCU28_RS12580	COG2195	Cleaves the N-terminal amino acid of tripeptides
OCU28_RS12585	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OCU28_RS12590	COG2249	NAD(P)H dehydrogenase (quinone) activity
OCU28_RS12605	COG1566	PFAM secretion protein HlyD family protein
OCU28_RS12625	COG3272	Protein of unknown function (DUF1722)
OCU28_RS12630	COG0415	Belongs to the DNA photolyase family
OCU28_RS12635	COG1388	LysM domain
OCU28_RS12635	COG1376	ErfK ybiS ycfS ynhG family protein
OCU28_RS12645	COG0513	Belongs to the DEAD box helicase family
OCU28_RS12655	COG0573	inorganic phosphate transmembrane transporter activity
OCU28_RS12660	COG0581	inorganic phosphate transmembrane transporter activity
OCU28_RS12665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OCU28_RS12700	COG3842	ATPase activity
OCU28_RS12710	COG1175	transmembrane transport
OCU28_RS12715	COG3833	ABC-type maltose transport systems, permease component
OCU28_RS12730	COG0739	heme binding
OCU28_RS12750	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
OCU28_RS12780	COG0583	DNA-binding transcription factor activity
OCU28_RS12810	COG1067	ATP-dependent peptidase activity
OCU28_RS12830	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OCU28_RS12835	COG0418	dihydroorotase activity
OCU28_RS12840	COG0633	Ferredoxin
OCU28_RS12840	COG3217	Mosc domain protein beta barrel domain protein
OCU28_RS12875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OCU28_RS12890	COG2223	nitrite transmembrane transporter activity
OCU28_RS12895	COG3279	Response regulator of the LytR AlgR family
OCU28_RS12900	COG3275	phosphorelay sensor kinase activity
OCU28_RS12905	COG1278	Cold shock
OCU28_RS12910	COG0793	Belongs to the peptidase S41A family
OCU28_RS12925	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCU28_RS12930	COG0800	Aldolase
OCU28_RS12935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCU28_RS12940	COG1917	Cupin 2, conserved barrel domain protein
OCU28_RS12960	COG2186	Transcriptional regulator
OCU28_RS12965	COG2186	Transcriptional regulator
OCU28_RS12970	COG0517	IMP dehydrogenase activity
OCU28_RS12975	COG2176	DNA-directed DNA polymerase activity
OCU28_RS13015	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCU28_RS13020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCU28_RS13055	COG1028	Short-chain dehydrogenase reductase Sdr
OCU28_RS13060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCU28_RS13065	COG0577	efflux transmembrane transporter activity
OCU28_RS13065	COG1136	(ABC) transporter
OCU28_RS13070	COG2205	protein histidine kinase activity
OCU28_RS13075	COG0745	RESPONSE REGULATOR receiver
OCU28_RS13080	COG0583	DNA-binding transcription factor activity
OCU28_RS13095	COG0583	DNA-binding transcription factor activity
OCU28_RS13120	COG0583	DNA-binding transcription factor activity
OCU28_RS13165	COG1757	Na H antiporter
OCU28_RS13235	COG1116	anion transmembrane transporter activity
OCU28_RS13240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCU28_RS13245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OCU28_RS13250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OCU28_RS13255	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OCU28_RS13260	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OCU28_RS13275	COG2850	peptidyl-arginine hydroxylation
OCU28_RS13295	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OCU28_RS13310	COG3097	Belongs to the UPF0267 family
OCU28_RS13320	COG0625	glutathione transferase activity
OCU28_RS13325	COG2501	S4 domain
OCU28_RS13335	COG1979	alcohol dehydrogenase
OCU28_RS13345	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
OCU28_RS13355	COG0513	Belongs to the DEAD box helicase family
OCU28_RS13360	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OCU28_RS13385	COG1280	lysine exporter protein (LysE YggA)
OCU28_RS13390	COG1335	isochorismatase
OCU28_RS13400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OCU28_RS13405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OCU28_RS13410	COG2146	nitrite reductase [NAD(P)H] activity
OCU28_RS13415	COG2116	formate transmembrane transporter activity
OCU28_RS13420	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OCU28_RS13420	COG1648	precorrin-2 dehydrogenase activity
OCU28_RS13440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OCU28_RS13450	COG0545	Peptidyl-prolyl cis-trans isomerase
OCU28_RS13460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCU28_RS13475	COG0546	phosphoglycolate phosphatase activity
OCU28_RS13480	COG3118	belongs to the thioredoxin family
OCU28_RS13485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OCU28_RS13515	COG1328	CTP reductase activity
OCU28_RS13520	COG0602	queuosine metabolic process
OCU28_RS13530	COG0189	ligase activity
OCU28_RS13530	COG4067	protein conserved in archaea
OCU28_RS13535	COG0725	ABC transporter, periplasmic molybdate-binding protein
OCU28_RS13540	COG4149	molybdate abc transporter
OCU28_RS13545	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OCU28_RS13560	COG2176	DNA-directed DNA polymerase activity
OCU28_RS13570	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
OCU28_RS13575	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
OCU28_RS13585	COG0745	RESPONSE REGULATOR receiver
OCU28_RS13595	COG3140	Belongs to the UPF0181 family
OCU28_RS13620	COG2084	Dehydrogenase
OCU28_RS13635	COG0023	Translation Initiation Factor
OCU28_RS13645	COG1181	Belongs to the D-alanine--D-alanine ligase family
OCU28_RS13655	COG0045	succinate-CoA ligase (ADP-forming) activity
OCU28_RS13655	COG1042	CoA-binding domain protein
OCU28_RS13655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCU28_RS13670	COG0583	DNA-binding transcription factor activity
OCU28_RS13680	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OCU28_RS13685	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OCU28_RS13695	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OCU28_RS13700	COG4181	ATPase activity
OCU28_RS13710	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OCU28_RS13715	COG3300	MHYT domain
OCU28_RS13715	COG5001	Diguanylate cyclase
OCU28_RS13725	COG0366	Alpha amylase catalytic
OCU28_RS13745	COG2425	protein containing a von Willebrand factor type A (vWA) domain
OCU28_RS13750	COG0714	Associated with various cellular activities
OCU28_RS13755	COG0494	nUDIX hydrolase
OCU28_RS13760	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
OCU28_RS13765	COG0513	Belongs to the DEAD box helicase family
OCU28_RS13770	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
OCU28_RS13775	COG4977	sequence-specific DNA binding
OCU28_RS13775	COG1917	Cupin 2, conserved barrel domain protein
OCU28_RS13785	COG0671	phosphoesterase, PA-phosphatase related
OCU28_RS13795	COG0513	Belongs to the DEAD box helicase family
OCU28_RS13805	COG4166	transmembrane transport
OCU28_RS13810	COG4174	ABC transporter (Permease)
OCU28_RS13815	COG4239	(ABC) transporter, permease
OCU28_RS13825	COG4172	Belongs to the ABC transporter superfamily
OCU28_RS13830	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OCU28_RS13855	COG2050	protein possibly involved in aromatic compounds catabolism
OCU28_RS13865	COG2824	Alkylphosphonate utilization operon protein PhnA
OCU28_RS13875	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
OCU28_RS13890	COG0737	Belongs to the 5'-nucleotidase family
OCU28_RS13895	COG3593	DNA synthesis involved in DNA repair
OCU28_RS13905	COG2353	YceI-like domain
OCU28_RS13910	COG3038	cytochrome b561
OCU28_RS13925	COG0786	glutamate:sodium symporter activity
OCU28_RS13930	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OCU28_RS13935	COG0363	glucosamine-6-phosphate deaminase activity
OCU28_RS13940	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OCU28_RS13950	COG3530	Putative quorum-sensing-regulated virulence factor
OCU28_RS13990	COG0583	DNA-binding transcription factor activity
OCU28_RS14005	COG1063	alcohol dehydrogenase
OCU28_RS14010	COG0156	8-amino-7-oxononanoate synthase activity
OCU28_RS14020	COG2723	6-phospho-beta-galactosidase activity
OCU28_RS14025	COG0653	protein targeting
OCU28_RS14040	COG0848	biopolymer transport protein
OCU28_RS14045	COG0811	peptide transport
OCU28_RS14050	COG0811	peptide transport
OCU28_RS14075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OCU28_RS14080	COG0515	serine threonine protein kinase
OCU28_RS14080	COG2815	serine threonine protein kinase
OCU28_RS14085	COG2223	nitrite transmembrane transporter activity
OCU28_RS14095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OCU28_RS14105	COG0243	molybdopterin cofactor binding
OCU28_RS14120	COG0393	Putative heavy-metal-binding
OCU28_RS14125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OCU28_RS14150	COG0714	Associated with various cellular activities
OCU28_RS14190	COG0531	amino acid
OCU28_RS14200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCU28_RS14210	COG0642	Histidine kinase
OCU28_RS14215	COG0745	RESPONSE REGULATOR receiver
OCU28_RS14225	COG1765	OsmC-like protein
OCU28_RS14230	COG1278	Cold shock
OCU28_RS14235	COG4681	YaeQ
OCU28_RS14245	COG0628	permease
OCU28_RS14260	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OCU28_RS14270	COG0300	oxidoreductase activity
OCU28_RS14285	COG0714	Associated with various cellular activities
OCU28_RS14300	COG2304	oxidoreductase activity
OCU28_RS14330	COG0556	nucleotide-excision repair
OCU28_RS14345	COG3344	reverse transcriptase
OCU28_RS14370	COG4974	Belongs to the 'phage' integrase family
OCU28_RS14405	COG3833	ABC-type maltose transport systems, permease component
OCU28_RS14410	COG1175	transmembrane transport
OCU28_RS14415	COG2182	Extracellular solute-binding protein
OCU28_RS14425	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCU28_RS14435	COG3842	ATPase activity
OCU28_RS14480	COG0583	DNA-binding transcription factor activity
OCU28_RS14485	COG1518	maintenance of DNA repeat elements
OCU28_RS14490	COG1203	CRISPR-associated helicase, Cas3
OCU28_RS14520	COG1619	proteins homologs of microcin C7 resistance protein MccF
OCU28_RS14525	COG3477	response to acidic pH
OCU28_RS14625	COG0516	GMP reductase activity
OCU28_RS14630	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OCU28_RS14630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OCU28_RS14650	COG0583	DNA-binding transcription factor activity
OCU28_RS14655	COG4221	oxidoreductase activity
OCU28_RS14670	COG0346	lactoylglutathione lyase activity
OCU28_RS14675	COG2221	Nitrite and sulphite reductase 4Fe-4S
OCU28_RS14675	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OCU28_RS14680	COG3381	protein complex oligomerization
OCU28_RS14685	COG3302	dmso reductase anchor subunit
OCU28_RS14690	COG0437	4 iron, 4 sulfur cluster binding
OCU28_RS14695	COG0243	molybdopterin cofactor binding
OCU28_RS14700	COG2814	Major facilitator Superfamily
OCU28_RS14705	COG2814	Major facilitator Superfamily
OCU28_RS14720	COG4175	Glycine betaine
OCU28_RS14720	COG3448	diguanylate cyclase activity
OCU28_RS14725	COG4176	ABC-type proline glycine betaine transport system permease component
OCU28_RS14765	COG0531	amino acid
OCU28_RS14770	COG1584	GPR1 FUN34 yaaH family protein
OCU28_RS14775	COG0129	dihydroxy-acid dehydratase activity
OCU28_RS14780	COG3265	gluconokinase activity
OCU28_RS14785	COG1609	Transcriptional regulator
OCU28_RS14790	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OCU28_RS14800	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OCU28_RS14805	COG1028	Short-chain dehydrogenase reductase Sdr
OCU28_RS14820	COG0583	DNA-binding transcription factor activity
OCU28_RS14825	COG0513	Belongs to the DEAD box helicase family
OCU28_RS14845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OCU28_RS14850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OCU28_RS14860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OCU28_RS14870	COG1216	Glycosyl transferase, family 2
OCU28_RS14900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OCU28_RS14905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OCU28_RS14910	COG1028	Short-chain dehydrogenase reductase Sdr
OCU28_RS14920	COG0747	negative chemotaxis
OCU28_RS14935	COG0300	oxidoreductase activity
OCU28_RS14940	COG0523	cobalamin synthesis protein
OCU28_RS14955	COG4608	Belongs to the ABC transporter superfamily
OCU28_RS14960	COG0444	Belongs to the ABC transporter superfamily
OCU28_RS14965	COG0747	negative chemotaxis
OCU28_RS14970	COG4239	(ABC) transporter, permease
OCU28_RS14975	COG4174	ABC transporter (Permease)
OCU28_RS15000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OCU28_RS15010	COG3360	Dodecin
OCU28_RS15015	COG2197	response regulator
OCU28_RS15020	COG3850	Histidine kinase
OCU28_RS15030	COG3062	negative regulation of establishment of protein localization
OCU28_RS15035	COG0243	molybdopterin cofactor binding
OCU28_RS15040	COG3043	anaerobic respiration
OCU28_RS15075	COG1132	(ABC) transporter
OCU28_RS15085	COG0748	coenzyme F420 binding
OCU28_RS15090	COG3721	Heme iron utilization protein
OCU28_RS15105	COG0811	peptide transport
OCU28_RS15110	COG0848	biopolymer transport protein
OCU28_RS15120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCU28_RS15225	COG0484	heat shock protein binding
OCU28_RS15280	COG0038	chloride channel
OCU28_RS15310	COG1803	Methylglyoxal synthase
OCU28_RS15320	COG1735	metal-dependent hydrolase with the TIM-barrel fold
OCU28_RS15330	COG2188	Transcriptional regulator
OCU28_RS15335	COG0210	DNA helicase
OCU28_RS15340	COG1289	transmembrane transporter activity
OCU28_RS15345	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OCU28_RS15355	COG1566	PFAM secretion protein HlyD family protein
OCU28_RS15380	COG1879	ABC-type sugar transport system periplasmic component
OCU28_RS15390	COG3132	Protein of unknown function, DUF480
OCU28_RS15405	COG2226	methyltransferase
OCU28_RS15410	COG0583	DNA-binding transcription factor activity
OCU28_RS15425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCU28_RS15430	COG1942	4-Oxalocrotonate Tautomerase
OCU28_RS15435	COG0154	amidase activity
OCU28_RS15455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCU28_RS15465	COG4989	oxidoreductase activity
OCU28_RS15475	COG0366	Alpha amylase catalytic
OCU28_RS15490	COG2866	Carboxypeptidase
OCU28_RS15500	COG3038	cytochrome b561
OCU28_RS15505	COG2252	PERMEase
OCU28_RS15510	COG0737	Belongs to the 5'-nucleotidase family
OCU28_RS15530	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OCU28_RS15550	COG0443	Heat shock 70 kDa protein
OCU28_RS15555	COG0154	amidase activity
OCU28_RS15565	COG1247	-acetyltransferase
OCU28_RS15580	COG3180	Ammonia monooxygenase
OCU28_RS15585	COG0456	acetyltransferase
OCU28_RS15590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCU28_RS15595	COG0765	amino acid transport
OCU28_RS15600	COG1126	abc transporter atp-binding protein
OCU28_RS15605	COG0179	Fumarylacetoacetate (FAA) hydrolase
OCU28_RS15620	COG0509	glycine decarboxylation via glycine cleavage system
OCU28_RS15655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OCU28_RS15670	COG4172	Belongs to the ABC transporter superfamily
OCU28_RS15675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCU28_RS15685	COG0747	negative chemotaxis
OCU28_RS15705	COG1929	Belongs to the glycerate kinase type-1 family
OCU28_RS15710	COG0702	epimerase
OCU28_RS15745	COG0702	epimerase
OCU28_RS15750	COG0564	pseudouridine synthase activity
OCU28_RS15790	COG3278	Belongs to the heme-copper respiratory oxidase family
OCU28_RS15815	COG0583	DNA-binding transcription factor activity
OCU28_RS15820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OCU28_RS15835	COG1418	mRNA catabolic process
OCU28_RS15850	COG1304	FMN binding
OCU28_RS15855	COG1620	l-lactate permease
OCU28_RS15860	COG0583	DNA-binding transcription factor activity
OCU28_RS15865	COG1609	Transcriptional regulator
OCU28_RS15870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCU28_RS15875	COG1879	ABC-type sugar transport system periplasmic component
OCU28_RS15880	COG1172	Belongs to the binding-protein-dependent transport system permease family
OCU28_RS15885	COG1129	ABC transporter
OCU28_RS15890	COG1869	D-ribose catabolic process
OCU28_RS15920	COG2249	NAD(P)H dehydrogenase (quinone) activity
OCU28_RS15960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OCU28_RS15965	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OCU28_RS15970	COG0668	transmembrane transport
OCU28_RS15975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OCU28_RS16005	COG4580	involved in the transport of maltose and maltodextrins
OCU28_RS16015	COG3706	GGDEF domain
OCU28_RS16020	COG1132	(ABC) transporter
OCU28_RS16025	COG3138	arginine N-succinyltransferase
OCU28_RS16030	COG3724	N-succinylarginine dihydrolase activity
OCU28_RS16045	COG0583	DNA-binding transcription factor activity
OCU28_RS16050	COG2814	Major facilitator Superfamily
OCU28_RS16070	COG0668	transmembrane transport
OCU28_RS16075	COG0390	transport system, permease component
OCU28_RS16080	COG4667	esterase of the alpha-beta hydrolase superfamily
OCU28_RS16100	COG0583	DNA-binding transcription factor activity
OCU28_RS16105	COG0259	pyridoxamine-phosphate oxidase activity
OCU28_RS16110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCU28_RS16120	COG1444	tRNA N-acetyltransferase activity