locus-tag	class	description
BG259_RS00010	COG2165	general secretion pathway protein
BG259_RS00015	COG0735	belongs to the Fur family
BG259_RS00025	COG0716	FMN binding
BG259_RS00035	COG0596	Alpha beta hydrolase
BG259_RS00040	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BG259_RS00045	COG0033	Phosphoglucomutase
BG259_RS00060	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BG259_RS00075	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BG259_RS00080	COG1053	succinate dehydrogenase
BG259_RS00090	COG0567	Dehydrogenase, E1 component
BG259_RS00095	COG0508	dehydrogenase complex catalyzes the overall conversion of
BG259_RS00110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BG259_RS00115	COG1121	(ABC) transporter
BG259_RS00120	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BG259_RS00125	COG4977	sequence-specific DNA binding
BG259_RS00130	COG1918	ferrous iron import across plasma membrane
BG259_RS00160	COG3102	Protein conserved in bacteria
BG259_RS00165	COG0788	formyltetrahydrofolate deformylase activity
BG259_RS00170	COG1199	ATP-dependent helicase activity
BG259_RS00175	COG1214	PFAM Peptidase M22, glycoprotease
BG259_RS00185	COG3065	identical protein binding
BG259_RS00190	COG2267	carboxylic ester hydrolase activity
BG259_RS00195	COG0318	PFAM AMP-dependent synthetase and ligase
BG259_RS00200	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BG259_RS00205	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BG259_RS00210	COG2894	cell division
BG259_RS00225	COG2951	lytic endotransglycosylase activity
BG259_RS00235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BG259_RS00270	COG1028	Short-chain dehydrogenase reductase Sdr
BG259_RS00305	COG2986	histidine ammonia-lyase
BG259_RS00310	COG1216	Glycosyl transferase, family 2
BG259_RS00330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BG259_RS00335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BG259_RS00365	COG2226	methyltransferase
BG259_RS00380	COG1028	Short-chain dehydrogenase reductase Sdr
BG259_RS00390	COG1169	isochorismate synthase
BG259_RS00395	COG1021	2,3-dihydroxybenzoate-AMP ligase
BG259_RS00400	COG3433	isochorismatase activity
BG259_RS00400	COG1535	isochorismatase
BG259_RS00405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BG259_RS00405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BG259_RS00420	COG4771	TonB-dependent receptor
BG259_RS00425	COG1253	flavin adenine dinucleotide binding
BG259_RS00430	COG0513	Belongs to the DEAD box helicase family
BG259_RS00435	COG0569	domain protein
BG259_RS00440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BG259_RS00455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BG259_RS00460	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BG259_RS00465	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BG259_RS00505	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BG259_RS00510	COG0776	regulation of translation
BG259_RS00515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BG259_RS00540	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BG259_RS00545	COG0436	Aminotransferase
BG259_RS00550	COG1169	isochorismate synthase
BG259_RS00560	COG0596	Alpha beta hydrolase
BG259_RS00565	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BG259_RS00580	COG2190	(PTS) system
BG259_RS00580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG259_RS00580	COG1263	PTS System
BG259_RS00585	COG0583	DNA-binding transcription factor activity
BG259_RS00600	COG2855	membrane
BG259_RS00655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG259_RS00680	COG1522	sequence-specific DNA binding
BG259_RS00690	COG1946	Acyl-CoA thioesterase
BG259_RS00695	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BG259_RS00725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BG259_RS00730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BG259_RS00735	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BG259_RS00740	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BG259_RS00745	COG0517	IMP dehydrogenase activity
BG259_RS00745	COG0617	tRNA 3'-terminal CCA addition
BG259_RS00745	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BG259_RS00755	COG2217	Heavy metal translocating P-type atpase
BG259_RS00775	COG0537	adenosine 5'-monophosphoramidase activity
BG259_RS00805	COG1252	NADH dehydrogenase
BG259_RS00820	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BG259_RS00830	COG4591	ABC-type transport system involved in lipoprotein release permease component
BG259_RS00835	COG1136	(ABC) transporter
BG259_RS00840	COG4591	ABC-type transport system involved in lipoprotein release permease component
BG259_RS00855	COG1132	(ABC) transporter
BG259_RS00875	COG2719	SpoVR family
BG259_RS00880	COG2718	Belongs to the UPF0229 family
BG259_RS00885	COG2766	serine protein kinase
BG259_RS00900	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BG259_RS00910	COG1882	Formate acetyltransferase
BG259_RS00945	COG0708	Exodeoxyribonuclease III
BG259_RS00950	COG0840	transmembrane signaling receptor activity
BG259_RS00965	COG0730	response to heat
BG259_RS00970	COG1199	ATP-dependent helicase activity
BG259_RS00980	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BG259_RS00985	COG1187	pseudouridine synthase activity
BG259_RS00995	COG1278	Cold shock
BG259_RS01005	COG0542	response to heat
BG259_RS01010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BG259_RS01040	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BG259_RS01045	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BG259_RS01050	COG0297	glycogen (starch) synthase activity
BG259_RS01070	COG3070	regulator of competence-specific genes
BG259_RS01085	COG0745	RESPONSE REGULATOR receiver
BG259_RS01090	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BG259_RS01095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BG259_RS01105	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BG259_RS01110	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BG259_RS01125	COG0189	ligase activity
BG259_RS01125	COG4067	protein conserved in archaea
BG259_RS01140	COG1801	Protein of unknown function DUF72
BG259_RS01155	COG0840	transmembrane signaling receptor activity
BG259_RS01160	COG0632	four-way junction helicase activity
BG259_RS01170	COG1271	oxidase subunit
BG259_RS01175	COG1294	oxidase, subunit
BG259_RS01180	COG4890	Cyd operon protein YbgT
BG259_RS01190	COG0824	Thioesterase
BG259_RS01195	COG0811	peptide transport
BG259_RS01210	COG0823	Involved in the tonB-independent uptake of proteins
BG259_RS01215	COG2885	chlorophyll binding
BG259_RS01220	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BG259_RS01235	COG0673	inositol 2-dehydrogenase activity
BG259_RS01240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG259_RS01240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BG259_RS01240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG259_RS01245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BG259_RS01250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BG259_RS01255	COG1882	Formate acetyltransferase
BG259_RS01260	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BG259_RS01265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BG259_RS01270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BG259_RS01275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BG259_RS01280	COG2207	Transcriptional regulator
BG259_RS01285	COG0371	Dehydrogenase
BG259_RS01290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BG259_RS01310	COG3766	membrane
BG259_RS01320	COG0754	glutathionylspermidine amidase activity
BG259_RS01330	COG0784	Response regulator, receiver
BG259_RS01330	COG5002	protein histidine kinase activity
BG259_RS01410	COG4669	(LipO)protein
BG259_RS01455	COG4792	protein secretion
BG259_RS01460	COG4791	protein targeting
BG259_RS01465	COG4794	Type iii secretion
BG259_RS01470	COG4790	Type iii secretion
BG259_RS01540	COG0457	Tetratricopeptide repeat
BG259_RS01555	COG0789	Transcriptional regulator
BG259_RS01560	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BG259_RS01575	COG1263	PTS System
BG259_RS01575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG259_RS01580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG259_RS01585	COG1621	beta-fructofuranosidase activity
BG259_RS01590	COG2824	Alkylphosphonate utilization operon protein PhnA
BG259_RS01605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BG259_RS01630	COG0534	Mate efflux family protein
BG259_RS01635	COG0444	Belongs to the ABC transporter superfamily
BG259_RS01640	COG4608	Belongs to the ABC transporter superfamily
BG259_RS01645	COG0747	negative chemotaxis
BG259_RS01660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BG259_RS01675	COG2076	Multidrug Resistance protein
BG259_RS01700	COG0583	DNA-binding transcription factor activity
BG259_RS01705	COG4771	TonB-dependent receptor
BG259_RS01725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BG259_RS01730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG259_RS01740	COG2186	Transcriptional regulator
BG259_RS01755	COG1288	antiporter activity
BG259_RS01785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG259_RS01800	COG2176	DNA-directed DNA polymerase activity
BG259_RS01805	COG0517	IMP dehydrogenase activity
BG259_RS01810	COG2186	Transcriptional regulator
BG259_RS01815	COG1028	Short-chain dehydrogenase reductase Sdr
BG259_RS01820	COG2186	Transcriptional regulator
BG259_RS01840	COG1917	Cupin 2, conserved barrel domain protein
BG259_RS01845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG259_RS01850	COG0800	Aldolase
BG259_RS01855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG259_RS01870	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BG259_RS01895	COG3568	Endonuclease Exonuclease Phosphatase
BG259_RS01905	COG4934	collagen metabolic process
BG259_RS01940	COG0686	Belongs to the AlaDH PNT family
BG259_RS01950	COG1674	ftsk spoiiie
BG259_RS01960	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BG259_RS01980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BG259_RS01985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BG259_RS02020	COG0300	oxidoreductase activity
BG259_RS02035	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BG259_RS02045	COG2268	Band 7 protein
BG259_RS02055	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BG259_RS02065	COG0482	sulfurtransferase activity
BG259_RS02075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG259_RS02085	COG1757	Na H antiporter
BG259_RS02095	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BG259_RS02100	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BG259_RS02105	COG0131	Imidazoleglycerol-phosphate dehydratase
BG259_RS02105	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BG259_RS02110	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BG259_RS02115	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BG259_RS02125	COG0140	phosphoribosyl-ATP diphosphatase activity
BG259_RS02125	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BG259_RS02130	COG3012	SEC-C Motif Domain Protein
BG259_RS02135	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BG259_RS02140	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BG259_RS02145	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BG259_RS02150	COG0215	cysteine-tRNA ligase activity
BG259_RS02155	COG1435	thymidine kinase activity
BG259_RS02160	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BG259_RS02185	COG2116	formate transmembrane transporter activity
BG259_RS02190	COG0390	transport system, permease component
BG259_RS02195	COG4459	periplasmic nitrate reductase
BG259_RS02200	COG3005	denitrification pathway
BG259_RS02205	COG0243	molybdopterin cofactor binding
BG259_RS02220	COG1121	(ABC) transporter
BG259_RS02225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BG259_RS02230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BG259_RS02235	COG1227	inorganic diphosphatase activity
BG259_RS02245	COG4172	Belongs to the ABC transporter superfamily
BG259_RS02255	COG4171	peptide transport system, permease
BG259_RS02270	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BG259_RS02275	COG1842	Phage shock protein A
BG259_RS02305	COG2818	Glycosylase
BG259_RS02310	COG5380	lipid catabolic process
BG259_RS02315	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BG259_RS02320	COG0626	cystathionine gamma-synthase activity
BG259_RS02330	COG0733	neurotransmitter:sodium symporter activity
BG259_RS02340	COG0564	pseudouridine synthase activity
BG259_RS02350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BG259_RS02355	COG1151	hydroxylamine reductase activity
BG259_RS02360	COG3604	Transcriptional regulator
BG259_RS02365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BG259_RS02370	COG4136	ATPase activity
BG259_RS02375	COG4135	transport system, permease component
BG259_RS02380	COG4134	Bacterial extracellular solute-binding protein
BG259_RS02385	COG0398	Pfam SNARE associated Golgi protein
BG259_RS02395	COG0493	'glutamate synthase
BG259_RS02420	COG0659	secondary active sulfate transmembrane transporter activity
BG259_RS02430	COG3313	Fe-S protein
BG259_RS02485	COG1061	Type III restriction enzyme res subunit
BG259_RS02490	COG1187	pseudouridine synthase activity
BG259_RS02495	COG2814	Major facilitator Superfamily
BG259_RS02505	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG259_RS02515	COG1609	Transcriptional regulator
BG259_RS02520	COG0702	epimerase
BG259_RS02525	COG0534	Mate efflux family protein
BG259_RS02530	COG4181	ATPase activity
BG259_RS02560	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BG259_RS02570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BG259_RS02580	COG1737	Transcriptional regulator
BG259_RS02585	COG0076	glutamate decarboxylase activity
BG259_RS02595	COG2431	L-lysine efflux transmembrane transporter activity
BG259_RS02605	COG3070	regulator of competence-specific genes
BG259_RS02620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG259_RS02620	COG4191	Histidine kinase
BG259_RS02630	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BG259_RS02640	COG5001	Diguanylate cyclase
BG259_RS02640	COG5002	protein histidine kinase activity
BG259_RS02640	COG3447	MASE1 domain protein
BG259_RS02660	COG0583	DNA-binding transcription factor activity
BG259_RS02665	COG2610	gluconate transmembrane transporter activity
BG259_RS02675	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BG259_RS02680	COG4988	ABC transporter
BG259_RS02685	COG0492	ferredoxin-NADP+ reductase activity
BG259_RS02705	COG3706	GGDEF domain
BG259_RS02710	COG0471	metal ion transport
BG259_RS02715	COG2949	membrane
BG259_RS02725	COG1643	Atp-dependent helicase
BG259_RS02770	COG0471	metal ion transport
BG259_RS02775	COG4191	Histidine kinase
BG259_RS02775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG259_RS02785	COG3300	MHYT domain
BG259_RS02785	COG5001	Diguanylate cyclase
BG259_RS02795	COG1280	lysine exporter protein (LysE YggA)
BG259_RS02800	COG1328	CTP reductase activity
BG259_RS02805	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BG259_RS02815	COG0861	Integral membrane protein TerC family
BG259_RS02825	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BG259_RS02835	COG1454	alcohol dehydrogenase
BG259_RS02840	COG0814	amino acid
BG259_RS02855	COG1120	ATPase activity
BG259_RS02860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG259_RS02865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG259_RS02870	COG4774	siderophore transport
BG259_RS02885	COG1132	(ABC) transporter
BG259_RS02890	COG1132	(ABC) transporter
BG259_RS02895	COG2165	general secretion pathway protein
BG259_RS02905	COG0583	DNA-binding transcription factor activity
BG259_RS02930	COG0443	Heat shock 70 kDa protein
BG259_RS02935	COG0443	Heat shock 70 kDa protein
BG259_RS02945	COG3706	GGDEF domain
BG259_RS02975	COG0243	molybdopterin cofactor binding
BG259_RS02980	COG0437	4 iron, 4 sulfur cluster binding
BG259_RS02985	COG3302	dmso reductase anchor subunit
BG259_RS03000	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BG259_RS03005	COG1643	Atp-dependent helicase
BG259_RS03030	COG3063	Type IV pilus biogenesis stability protein PilW
BG259_RS03055	COG0531	amino acid
BG259_RS03060	COG1280	lysine exporter protein (LysE YggA)
BG259_RS03065	COG0583	DNA-binding transcription factor activity
BG259_RS03070	COG1560	Kdo2-lipid A biosynthetic process
BG259_RS03090	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BG259_RS03095	COG2197	response regulator
BG259_RS03130	COG1280	lysine exporter protein (LysE YggA)
BG259_RS03150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG259_RS03155	COG2358	TRAP transporter, solute receptor (TAXI family
BG259_RS03160	COG0730	response to heat
BG259_RS03185	COG0456	acetyltransferase
BG259_RS03195	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BG259_RS03305	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BG259_RS03310	COG0372	Belongs to the citrate synthase family
BG259_RS03320	COG2828	Protein conserved in bacteria
BG259_RS03355	COG0561	phosphatase activity
BG259_RS03360	COG0602	queuosine metabolic process
BG259_RS03370	COG2199	diguanylate cyclase activity
BG259_RS03370	COG2203	Gaf domain
BG259_RS03400	COG3064	Membrane
BG259_RS03410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BG259_RS03415	COG1215	transferase activity, transferring glycosyl groups
BG259_RS03420	COG0297	glycogen (starch) synthase activity
BG259_RS03450	COG0438	transferase activity, transferring glycosyl groups
BG259_RS03460	COG2204	response regulator
BG259_RS03480	COG2885	chlorophyll binding
BG259_RS03490	COG1793	dna ligase
BG259_RS03500	COG0534	Mate efflux family protein
BG259_RS03505	COG0307	riboflavin synthase, alpha
BG259_RS03515	COG3001	Fructosamine kinase
BG259_RS03520	COG2201	protein-glutamate methylesterase activity
BG259_RS03525	COG3706	GGDEF domain
BG259_RS03535	COG0791	NLP P60 protein
BG259_RS03540	COG0840	transmembrane signaling receptor activity
BG259_RS03580	COG3148	PFAM DTW domain containing protein
BG259_RS03585	COG1940	carbohydrate kinase activity
BG259_RS03595	COG0303	'Molybdopterin
BG259_RS03605	COG3842	ATPase activity
BG259_RS03610	COG4662	Binding-protein-dependent transport system inner membrane component
BG259_RS03620	COG2204	response regulator
BG259_RS03625	COG4191	Histidine kinase
BG259_RS03640	COG0488	(ABC) transporter
BG259_RS03645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BG259_RS03675	COG0243	molybdopterin cofactor binding
BG259_RS03675	COG3383	formate dehydrogenase (NAD+) activity
BG259_RS03680	COG0437	4 iron, 4 sulfur cluster binding
BG259_RS03700	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BG259_RS03710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BG259_RS03720	COG1177	transmembrane transport
BG259_RS03730	COG3842	ATPase activity
BG259_RS03740	COG2992	FlgJ-related protein
BG259_RS03755	COG0589	response to stress
BG259_RS03760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BG259_RS03775	COG2217	Heavy metal translocating P-type atpase
BG259_RS03785	COG2010	Cytochrome c
BG259_RS03800	COG3278	Belongs to the heme-copper respiratory oxidase family
BG259_RS03815	COG0784	Response regulator, receiver
BG259_RS03815	COG2205	protein histidine kinase activity
BG259_RS03920	COG1067	ATP-dependent peptidase activity
BG259_RS03925	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BG259_RS03940	COG0488	(ABC) transporter
BG259_RS03965	COG2902	Dehydrogenase
BG259_RS03975	COG0308	aminopeptidase N
BG259_RS03990	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BG259_RS03995	COG1956	GAF domain-containing protein
BG259_RS04000	COG1132	(ABC) transporter
BG259_RS04005	COG2995	paraquat-inducible protein a
BG259_RS04010	COG3008	intermembrane lipid transfer
BG259_RS04035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BG259_RS04055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG259_RS04060	COG4597	amino acid ABC transporter
BG259_RS04065	COG0765	amino acid transport
BG259_RS04070	COG1126	abc transporter atp-binding protein
BG259_RS04075	COG0670	Belongs to the BI1 family
BG259_RS04080	COG2920	part of a sulfur-relay system
BG259_RS04085	COG1254	Belongs to the acylphosphatase family
BG259_RS04090	COG0840	transmembrane signaling receptor activity
BG259_RS04180	COG5001	Diguanylate cyclase
BG259_RS04180	COG3300	MHYT domain
BG259_RS04185	COG4999	Histidine kinase
BG259_RS04185	COG3850	Histidine kinase
BG259_RS04185	COG3437	response regulator, receiver
BG259_RS04185	COG2205	protein histidine kinase activity
BG259_RS04200	COG0110	maltose O-acetyltransferase activity
BG259_RS04225	COG1846	Transcriptional regulator
BG259_RS04235	COG3247	response to pH
BG259_RS04240	COG0668	transmembrane transport
BG259_RS04255	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BG259_RS04315	COG4964	Belongs to the GSP D family
BG259_RS04340	COG2207	Transcriptional regulator
BG259_RS04360	COG0589	response to stress
BG259_RS04365	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BG259_RS04370	COG0363	glucosamine-6-phosphate deaminase activity
BG259_RS04375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BG259_RS04385	COG4774	siderophore transport
BG259_RS04390	COG4565	transcriptional regulatory protein
BG259_RS04395	COG3290	protein histidine kinase activity
BG259_RS04410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BG259_RS04430	COG0583	DNA-binding transcription factor activity
BG259_RS04435	COG2814	Major facilitator Superfamily
BG259_RS04450	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BG259_RS04480	COG2186	Transcriptional regulator
BG259_RS04495	COG0702	epimerase
BG259_RS04500	COG0583	DNA-binding transcription factor activity
BG259_RS04505	COG1404	Belongs to the peptidase S8 family
BG259_RS04510	COG1858	cytochrome C peroxidase
BG259_RS04520	COG0527	aspartate kinase activity
BG259_RS04525	COG0662	Cupin 2, conserved barrel domain protein
BG259_RS04530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BG259_RS04535	COG0456	acetyltransferase
BG259_RS04540	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BG259_RS04550	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BG259_RS04555	COG0534	Mate efflux family protein
BG259_RS04570	COG1368	sulfuric ester hydrolase activity
BG259_RS04600	COG1115	amino acid carrier protein
BG259_RS04605	COG1012	belongs to the aldehyde dehydrogenase family
BG259_RS04610	COG3284	Transcriptional regulator
BG259_RS04640	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BG259_RS04650	COG3051	citrate lyase alpha subunit
BG259_RS04655	COG2301	Belongs to the HpcH HpaI aldolase family
BG259_RS04665	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
BG259_RS04675	COG3630	sodium ion export across plasma membrane
BG259_RS04680	COG5016	pyruvate
BG259_RS04680	COG0511	ligase activity, forming carbon-carbon bonds
BG259_RS04685	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BG259_RS04695	COG4565	transcriptional regulatory protein
BG259_RS04795	COG0625	glutathione transferase activity
BG259_RS04805	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BG259_RS04820	COG2195	Cleaves the N-terminal amino acid of tripeptides
BG259_RS04830	COG0601	transmembrane transport
BG259_RS04835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG259_RS04840	COG0444	Belongs to the ABC transporter superfamily
BG259_RS04865	COG3291	Pkd domain containing protein
BG259_RS04890	COG1177	transmembrane transport
BG259_RS04895	COG1176	ABC-type spermidine putrescine transport system, permease component I
BG259_RS04900	COG3842	ATPase activity
BG259_RS04905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BG259_RS04910	COG2423	ornithine cyclodeaminase activity
BG259_RS04920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BG259_RS04925	COG3938	Belongs to the proline racemase family
BG259_RS04955	COG1451	nucleotide metabolic process
BG259_RS04960	COG2165	general secretion pathway protein
BG259_RS04985	COG0583	DNA-binding transcription factor activity
BG259_RS05045	COG4139	cobalamin transport
BG259_RS05060	COG2062	phosphohistidine phosphatase, SixA
BG259_RS05070	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BG259_RS05080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BG259_RS05085	COG0702	epimerase
BG259_RS05090	COG1823	symporter activity
BG259_RS05100	COG2925	Exonuclease
BG259_RS05110	COG1346	cytolysis
BG259_RS05175	COG0072	phenylalanine-tRNA ligase activity
BG259_RS05175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG259_RS05230	COG0251	oxidation-reduction process
BG259_RS05240	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BG259_RS05265	COG2188	Transcriptional regulator
BG259_RS05275	COG0010	Belongs to the arginase family
BG259_RS05285	COG2986	histidine ammonia-lyase
BG259_RS05305	COG0277	FAD linked oxidase domain protein
BG259_RS05305	COG0247	lactate metabolic process
BG259_RS05340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BG259_RS05475	COG3340	Belongs to the peptidase S51 family
BG259_RS05585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BG259_RS05605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BG259_RS05765	COG2026	Addiction module toxin, RelE StbE family
BG259_RS05785	COG1192	Involved in chromosome partitioning
BG259_RS06085	COG0791	NLP P60 protein
BG259_RS06205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG259_RS06220	COG3106	COG3106 Predicted ATPase
BG259_RS06235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BG259_RS06240	COG2205	protein histidine kinase activity
BG259_RS06240	COG0784	Response regulator, receiver
BG259_RS06255	COG0814	amino acid
BG259_RS06260	COG1760	l-serine dehydratase
BG259_RS06265	COG5001	Diguanylate cyclase
BG259_RS06265	COG3300	MHYT domain
BG259_RS06275	COG2197	response regulator
BG259_RS06280	COG0720	synthase
BG259_RS06285	COG0840	transmembrane signaling receptor activity
BG259_RS06290	COG0017	Asparaginyl-tRNA synthetase
BG259_RS06305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG259_RS06320	COG3437	response regulator, receiver
BG259_RS06320	COG2770	Histidine kinase
BG259_RS06325	COG1448	Aminotransferase
BG259_RS06350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BG259_RS06355	COG1846	Transcriptional regulator
BG259_RS06380	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BG259_RS06395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BG259_RS06400	COG3108	Peptidase M15
BG259_RS06405	COG2989	Protein conserved in bacteria
BG259_RS06430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BG259_RS06440	COG3088	subunit of a heme lyase
BG259_RS06440	COG4235	cytochrome complex assembly
BG259_RS06450	COG1138	Cytochrome C-type biogenesis protein
BG259_RS06455	COG3301	Polysulphide reductase, NrfD
BG259_RS06460	COG0437	4 iron, 4 sulfur cluster binding
BG259_RS06470	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BG259_RS06490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BG259_RS06500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BG259_RS06505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BG259_RS06530	COG0019	diaminopimelate decarboxylase activity
BG259_RS06580	COG0322	excinuclease ABC activity
BG259_RS06585	COG2197	response regulator
BG259_RS06590	COG0417	DNA replication proofreading
BG259_RS06610	COG1187	pseudouridine synthase activity
BG259_RS06620	COG0009	L-threonylcarbamoyladenylate synthase
BG259_RS06625	COG0613	PHP domain protein
BG259_RS06635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BG259_RS06640	COG0512	Glutamine amidotransferase of anthranilate synthase
BG259_RS06650	COG0135	phosphoribosylanthranilate isomerase activity
BG259_RS06650	COG0134	indole-3-glycerol-phosphate synthase activity
BG259_RS06660	COG0159	tryptophan synthase activity
BG259_RS06665	COG1301	dicarboxylic acid transport
BG259_RS06690	COG1607	acyl-coa hydrolase
BG259_RS06695	COG2350	Protein conserved in bacteria
BG259_RS06725	COG1716	ATPase activity
BG259_RS06725	COG5001	Diguanylate cyclase
BG259_RS06730	COG1032	radical SAM domain protein
BG259_RS06735	COG0446	pyridine nucleotide-disulphide oxidoreductase
BG259_RS06750	COG2964	Protein conserved in bacteria
BG259_RS06755	COG0840	transmembrane signaling receptor activity
BG259_RS06765	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BG259_RS06770	COG0463	Glycosyl transferase, family 2
BG259_RS06775	COG0745	RESPONSE REGULATOR receiver
BG259_RS06780	COG3850	Histidine kinase
BG259_RS06780	COG5002	protein histidine kinase activity
BG259_RS06815	COG1846	Transcriptional regulator
BG259_RS06860	COG1136	(ABC) transporter
BG259_RS06860	COG0577	efflux transmembrane transporter activity
BG259_RS06870	COG0577	efflux transmembrane transporter activity
BG259_RS06895	COG3153	acetyltransferase
BG259_RS06920	COG3118	belongs to the thioredoxin family
BG259_RS06925	COG4232	protein-disulfide reductase activity
BG259_RS06940	COG2995	paraquat-inducible protein a
BG259_RS06945	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BG259_RS06945	COG3008	intermembrane lipid transfer
BG259_RS06950	COG3009	Protein conserved in bacteria
BG259_RS07005	COG4166	transmembrane transport
BG259_RS07015	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BG259_RS07020	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BG259_RS07030	COG0539	negative regulation of cytoplasmic translation
BG259_RS07040	COG0616	signal peptide processing
BG259_RS07045	COG1028	Short-chain dehydrogenase reductase Sdr
BG259_RS07065	COG0835	chemotaxis
BG259_RS07065	COG0784	Response regulator, receiver
BG259_RS07070	COG1940	carbohydrate kinase activity
BG259_RS07080	COG4667	esterase of the alpha-beta hydrolase superfamily
BG259_RS07090	COG0733	neurotransmitter:sodium symporter activity
BG259_RS07100	COG1263	PTS System
BG259_RS07100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG259_RS07105	COG0084	hydrolase, TatD family'
BG259_RS07120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BG259_RS07150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG259_RS07165	COG1399	metal-binding, possibly nucleic acid-binding protein
BG259_RS07170	COG0424	maF-like protein
BG259_RS07175	COG0564	pseudouridine synthase activity
BG259_RS07180	COG1530	ribonuclease E activity
BG259_RS07190	COG0659	secondary active sulfate transmembrane transporter activity
BG259_RS07195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BG259_RS07200	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BG259_RS07230	COG2186	Transcriptional regulator
BG259_RS07240	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BG259_RS07245	COG0653	protein targeting
BG259_RS07250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BG259_RS07255	COG3706	GGDEF domain
BG259_RS07260	COG0366	Alpha amylase catalytic
BG259_RS07265	COG1122	ATPase activity
BG259_RS07270	COG4120	Belongs to the binding-protein-dependent transport system permease family
BG259_RS07295	COG0857	belongs to the CobB CobQ family
BG259_RS07295	COG0280	phosphate acetyltransferase
BG259_RS07300	COG3174	membrane
BG259_RS07305	COG0435	Glutathione S-transferase
BG259_RS07315	COG0444	Belongs to the ABC transporter superfamily
BG259_RS07320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG259_RS07325	COG0601	transmembrane transport
BG259_RS07335	COG0314	molybdopterin synthase activity
BG259_RS07340	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BG259_RS07350	COG0521	Mo-molybdopterin cofactor biosynthetic process
BG259_RS07355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BG259_RS07360	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BG259_RS07375	COG0556	nucleotide-excision repair
BG259_RS07385	COG1882	Formate acetyltransferase
BG259_RS07390	COG4657	Part of a membrane complex involved in electron transport
BG259_RS07400	COG4656	Part of a membrane complex involved in electron transport
BG259_RS07405	COG4658	electron transport chain
BG259_RS07410	COG4659	FMN binding
BG259_RS07415	COG4660	Part of a membrane complex involved in electron transport
BG259_RS07420	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BG259_RS07425	COG0346	lactoylglutathione lyase activity
BG259_RS07435	COG2885	chlorophyll binding
BG259_RS07445	COG2056	Na+-H+ antiporter family
BG259_RS07480	COG3451	type IV secretory pathway VirB4
BG259_RS07500	COG3736	Type IV secretory pathway, component VirB8
BG259_RS07505	COG3504	Conjugal transfer protein
BG259_RS07625	COG4974	Belongs to the 'phage' integrase family
BG259_RS07630	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BG259_RS07650	COG1454	alcohol dehydrogenase
BG259_RS07650	COG1012	belongs to the aldehyde dehydrogenase family
BG259_RS07655	COG2095	MarC family integral membrane protein
BG259_RS07660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BG259_RS07665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BG259_RS07670	COG1757	Na H antiporter
BG259_RS07695	COG3083	sulfuric ester hydrolase activity
BG259_RS07705	COG0123	including yeast histone deacetylase and acetoin utilization protein
BG259_RS07720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BG259_RS07725	COG0778	Nitroreductase
BG259_RS07730	COG0446	pyridine nucleotide-disulphide oxidoreductase
BG259_RS07730	COG1902	pentaerythritol trinitrate reductase activity
BG259_RS07735	COG0616	signal peptide processing
BG259_RS07740	COG0252	asparaginase activity
BG259_RS07745	COG3139	Protein of unknown function (DUF1315)
BG259_RS07755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BG259_RS07760	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BG259_RS07780	COG2226	methyltransferase
BG259_RS07800	COG1785	Belongs to the alkaline phosphatase family
BG259_RS07810	COG0346	lactoylglutathione lyase activity
BG259_RS07815	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BG259_RS07820	COG0668	transmembrane transport
BG259_RS07825	COG2261	transglycosylase associated protein
BG259_RS07835	COG2983	Belongs to the UPF0260 family
BG259_RS07845	COG2964	Protein conserved in bacteria
BG259_RS07855	COG0251	oxidation-reduction process
BG259_RS07860	COG0814	amino acid
BG259_RS07865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BG259_RS07870	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BG259_RS07880	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BG259_RS07890	COG2832	Protein of unknown function (DUF454)
BG259_RS07895	COG0745	RESPONSE REGULATOR receiver
BG259_RS07900	COG0583	DNA-binding transcription factor activity
BG259_RS07905	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BG259_RS07910	COG1286	toxin biosynthetic process
BG259_RS07915	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BG259_RS07920	COG0285	dihydrofolate synthase activity
BG259_RS07945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BG259_RS07950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BG259_RS07960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BG259_RS07980	COG3101	peptidyl-lysine hydroxylation
BG259_RS07985	COG2860	membrane
BG259_RS07995	COG2890	protein-(glutamine-N5) methyltransferase activity
BG259_RS08000	COG2840	Smr protein MutS2
BG259_RS08005	COG2062	phosphohistidine phosphatase, SixA
BG259_RS08025	COG0183	Belongs to the thiolase family
BG259_RS08045	COG2067	long-chain fatty acid transport protein
BG259_RS08050	COG2853	Lipoprotein
BG259_RS08055	COG4235	cytochrome complex assembly
BG259_RS08055	COG3088	subunit of a heme lyase
BG259_RS08065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BG259_RS08070	COG1138	Cytochrome C-type biogenesis protein
BG259_RS08085	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BG259_RS08090	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BG259_RS08095	COG4133	protoheme IX ABC transporter activity
BG259_RS08105	COG0835	chemotaxis
BG259_RS08115	COG1192	Involved in chromosome partitioning
BG259_RS08120	COG2201	protein-glutamate methylesterase activity
BG259_RS08125	COG0643	Histidine kinase
BG259_RS08125	COG0784	Response regulator, receiver
BG259_RS08125	COG2198	Histidine kinase
BG259_RS08130	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BG259_RS08165	COG1684	flagellar biosynthetic protein fliR
BG259_RS08170	COG1987	bacterial-type flagellum assembly
BG259_RS08225	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BG259_RS08235	COG1677	Flagellar hook-basal body complex protein FliE
BG259_RS08255	COG1516	flagellar protein fliS
BG259_RS08265	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BG259_RS08270	COG1334	flagellar protein FlaG
BG259_RS08275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BG259_RS08280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BG259_RS08290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BG259_RS08295	COG2211	Major facilitator Superfamily
BG259_RS08300	COG1486	melibiose metabolic process
BG259_RS08305	COG2169	Transcriptional regulator
BG259_RS08310	COG2837	iron assimilation
BG259_RS08335	COG1393	Belongs to the ArsC family
BG259_RS08355	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BG259_RS08360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BG259_RS08365	COG2716	regulation of RNA biosynthetic process
BG259_RS08370	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BG259_RS08385	COG4783	chaperone-mediated protein folding
BG259_RS08390	COG1393	Belongs to the ArsC family
BG259_RS08410	COG2233	PERMEase
BG259_RS08415	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BG259_RS08420	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BG259_RS08430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BG259_RS08435	COG0121	glutamine amidotransferase
BG259_RS08440	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BG259_RS08465	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BG259_RS08475	COG2226	methyltransferase
BG259_RS08485	COG0741	lytic transglycosylase activity
BG259_RS08485	COG1388	LysM domain
BG259_RS08500	COG0347	Belongs to the P(II) protein family
BG259_RS08520	COG0587	DNA-directed DNA polymerase activity
BG259_RS08545	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BG259_RS08550	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BG259_RS08560	COG0750	zinc metalloprotease
BG259_RS08570	COG0575	Belongs to the CDS family
BG259_RS08575	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BG259_RS08600	COG0024	Methionine aminopeptidase
BG259_RS08615	COG0564	pseudouridine synthase activity
BG259_RS08620	COG3098	single-species biofilm formation
BG259_RS08660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BG259_RS08685	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BG259_RS08700	COG1720	tRNA m6t6A37 methyltransferase activity
BG259_RS08725	COG0733	neurotransmitter:sodium symporter activity
BG259_RS08740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BG259_RS08745	COG0514	ATP-dependent DNA helicase (RecQ)
BG259_RS08750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BG259_RS08765	COG1477	protein flavinylation
BG259_RS08775	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BG259_RS08795	COG0271	Belongs to the BolA IbaG family
BG259_RS08825	COG1595	DNA-templated transcription, initiation
BG259_RS08840	COG3248	Nucleoside-binding outer membrane protein
BG259_RS08845	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BG259_RS08850	COG0693	protein deglycase activity
BG259_RS08855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BG259_RS08860	COG2166	iron-sulfur cluster assembly
BG259_RS08865	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BG259_RS08870	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BG259_RS08885	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BG259_RS08885	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BG259_RS08895	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BG259_RS08900	COG1074	ATP-dependent DNA helicase activity
BG259_RS08905	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BG259_RS08925	COG3141	response to X-ray
BG259_RS08940	COG2171	N-acyltransferase activity
BG259_RS08945	COG0584	glycerophosphoryl diester phosphodiesterase
BG259_RS08950	COG2271	Major facilitator Superfamily
BG259_RS08955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BG259_RS08965	COG1349	DNA-binding transcription factor activity
BG259_RS08970	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BG259_RS08995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG259_RS09005	COG2017	converts alpha-aldose to the beta-anomer
BG259_RS09020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BG259_RS09025	COG0768	penicillin binding
BG259_RS09035	COG1609	Transcriptional regulator
BG259_RS09040	COG3250	beta-galactosidase activity
BG259_RS09045	COG2731	YhcH YjgK YiaL family protein
BG259_RS09050	COG0531	amino acid
BG259_RS09055	COG0583	DNA-binding transcription factor activity
BG259_RS09115	COG4964	Belongs to the GSP D family
BG259_RS09140	COG2169	Transcriptional regulator
BG259_RS09145	COG1022	Amp-dependent synthetase and ligase
BG259_RS09155	COG0583	DNA-binding transcription factor activity
BG259_RS09160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BG259_RS09165	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BG259_RS09175	COG0560	Phosphoserine phosphatase
BG259_RS09185	COG0813	purine-nucleoside phosphorylase activity
BG259_RS09195	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BG259_RS09205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BG259_RS09210	COG0084	hydrolase, TatD family'
BG259_RS09215	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BG259_RS09220	COG3706	GGDEF domain
BG259_RS09240	COG3153	acetyltransferase
BG259_RS09245	COG3154	lipid carrier protein
BG259_RS09255	COG0826	peptidase U32
BG259_RS09260	COG0826	peptidase U32
BG259_RS09265	COG0534	Mate efflux family protein
BG259_RS09285	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BG259_RS09305	COG0195	Participates in both transcription termination and antitermination
BG259_RS09325	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BG259_RS09335	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BG259_RS09340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BG259_RS09350	COG1534	Rna-binding protein
BG259_RS09355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BG259_RS09360	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BG259_RS09365	COG2027	D-alanyl-D-alanine carboxypeptidase
BG259_RS09375	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BG259_RS09380	COG0739	heme binding
BG259_RS09395	COG0316	Belongs to the HesB IscA family
BG259_RS09405	COG0628	permease
BG259_RS09420	COG0784	Response regulator, receiver
BG259_RS09420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG259_RS09420	COG2198	Histidine kinase
BG259_RS09420	COG2205	protein histidine kinase activity
BG259_RS09425	COG0747	negative chemotaxis
BG259_RS09435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG259_RS09440	COG0444	Belongs to the ABC transporter superfamily
BG259_RS09445	COG4608	Belongs to the ABC transporter superfamily
BG259_RS09455	COG2971	BadF BadG BcrA BcrD
BG259_RS09470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BG259_RS09475	COG3842	ATPase activity
BG259_RS09485	COG1840	ABC-type Fe3 transport system, periplasmic component
BG259_RS09490	COG0004	ammonium transporteR
BG259_RS09505	COG1049	propionate catabolic process, 2-methylcitrate cycle
BG259_RS09510	COG1752	Esterase of the alpha-beta hydrolase superfamily
BG259_RS09515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BG259_RS09520	COG1643	Atp-dependent helicase
BG259_RS09535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BG259_RS09545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BG259_RS09560	COG1560	Kdo2-lipid A biosynthetic process
BG259_RS09565	COG0842	Transport permease protein
BG259_RS09570	COG1131	(ABC) transporter
BG259_RS09575	COG0659	secondary active sulfate transmembrane transporter activity
BG259_RS09580	COG0288	reversible hydration of carbon dioxide
BG259_RS09595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG259_RS09600	COG0508	dehydrogenase complex catalyzes the overall conversion of
BG259_RS09605	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BG259_RS09610	COG2186	Transcriptional regulator
BG259_RS09635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BG259_RS09640	COG1459	type II secretion system
BG259_RS09650	COG0237	dephospho-CoA kinase activity
BG259_RS09655	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BG259_RS09660	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BG259_RS09685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BG259_RS09690	COG4137	Cytochrome C assembly protein
BG259_RS09695	COG4536	flavin adenine dinucleotide binding
BG259_RS09715	COG0612	Peptidase, M16
BG259_RS09720	COG1238	metal cluster binding
BG259_RS09730	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BG259_RS09735	COG0511	ligase activity, forming carbon-carbon bonds
BG259_RS09735	COG5016	pyruvate
BG259_RS09740	COG3630	sodium ion export across plasma membrane
BG259_RS09800	COG0527	aspartate kinase activity
BG259_RS09815	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BG259_RS09820	COG1546	Belongs to the CinA family
BG259_RS09830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BG259_RS09860	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BG259_RS09870	COG0148	phosphopyruvate hydratase activity
BG259_RS09880	COG3956	TIGRFAM MazG family protein
BG259_RS09885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BG259_RS09910	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BG259_RS09915	COG1381	Involved in DNA repair and RecF pathway recombination
BG259_RS09920	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BG259_RS09940	COG3086	response to oxidative stress
BG259_RS09955	COG1595	DNA-templated transcription, initiation
BG259_RS09960	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BG259_RS09970	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BG259_RS09990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BG259_RS09995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BG259_RS10005	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BG259_RS10015	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BG259_RS10025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BG259_RS10035	COG0583	DNA-binding transcription factor activity
BG259_RS10050	COG0668	transmembrane transport
BG259_RS10055	COG0191	fructose-bisphosphate aldolase activity
BG259_RS10075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BG259_RS10100	COG2356	endonuclease I
BG259_RS10105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BG259_RS10110	COG0189	ligase activity
BG259_RS10115	COG1678	Uncharacterized ACR, COG1678
BG259_RS10120	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BG259_RS10135	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BG259_RS10140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BG259_RS10145	COG0762	integral membrane protein
BG259_RS10160	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BG259_RS10165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BG259_RS10265	COG1012	belongs to the aldehyde dehydrogenase family
BG259_RS10310	COG3437	response regulator, receiver
BG259_RS10325	COG1486	melibiose metabolic process
BG259_RS10330	COG1447	Phosphotransferase system cellobiose-specific component IIA
BG259_RS10340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BG259_RS10360	COG1028	Short-chain dehydrogenase reductase Sdr
BG259_RS10370	COG0795	lipopolysaccharide-transporting ATPase activity
BG259_RS10375	COG0795	lipopolysaccharide-transporting ATPase activity
BG259_RS10385	COG2927	DNA polymerase III (CHI subunit)
BG259_RS10390	COG0525	valine-tRNA ligase activity
BG259_RS10400	COG0456	acetyltransferase
BG259_RS10440	COG0251	oxidation-reduction process
BG259_RS10445	COG0204	Acyl-transferase
BG259_RS10455	COG5007	Belongs to the BolA IbaG family
BG259_RS10465	COG2854	intermembrane phospholipid transfer
BG259_RS10470	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BG259_RS10475	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BG259_RS10480	COG1127	ABC transporter
BG259_RS10490	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BG259_RS10490	COG0517	IMP dehydrogenase activity
BG259_RS10500	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BG259_RS10505	COG1137	ATPase activity
BG259_RS10515	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BG259_RS10520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG259_RS10530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG259_RS10535	COG2239	Acts as a magnesium transporter
BG259_RS10540	COG0312	modulator of DNA gyrase
BG259_RS10550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BG259_RS10555	COG0564	pseudouridine synthase activity
BG259_RS10570	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BG259_RS10575	COG0312	modulator of DNA gyrase
BG259_RS10580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BG259_RS10585	COG3164	Protein of unknown function
BG259_RS10595	COG0424	maF-like protein
BG259_RS10600	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BG259_RS10605	COG1792	Involved in formation and maintenance of cell shape
BG259_RS10610	COG1077	Cell shape determining protein MreB Mrl
BG259_RS10645	COG2165	general secretion pathway protein
BG259_RS10655	COG1459	type II secretion system
BG259_RS10660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BG259_RS10670	COG3409	Peptidoglycan-binding domain 1 protein
BG259_RS10670	COG3267	Type II secretory pathway component ExeA
BG259_RS10695	COG2199	diguanylate cyclase activity
BG259_RS10695	COG2200	EAL domain
BG259_RS10700	COG0629	single-stranded DNA binding
BG259_RS10715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BG259_RS10725	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BG259_RS10735	COG0527	aspartate kinase activity
BG259_RS10740	COG1410	methionine synthase
BG259_RS10740	COG0646	methionine synthase
BG259_RS10815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BG259_RS10835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BG259_RS10840	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BG259_RS10940	COG0735	belongs to the Fur family
BG259_RS10955	COG0432	Pfam Uncharacterised protein family UPF0047
BG259_RS10965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BG259_RS10970	COG0305	Participates in initiation and elongation during chromosome replication
BG259_RS10990	COG0360	Binds together with S18 to 16S ribosomal RNA
BG259_RS10995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BG259_RS11000	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BG259_RS11045	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BG259_RS11055	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BG259_RS11055	COG0678	peroxiredoxin activity
BG259_RS11060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG259_RS11070	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BG259_RS11070	COG0165	Argininosuccinate lyase
BG259_RS11085	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BG259_RS11095	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BG259_RS11105	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BG259_RS11110	COG0460	homoserine dehydrogenase
BG259_RS11110	COG0527	aspartate kinase activity
BG259_RS11115	COG0626	cystathionine gamma-synthase activity
BG259_RS11125	COG0281	malic enzyme
BG259_RS11135	COG2906	2 iron, 2 sulfur cluster binding
BG259_RS11145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BG259_RS11160	COG2168	tRNA wobble position uridine thiolation
BG259_RS11165	COG2923	Belongs to the DsrF TusC family
BG259_RS11170	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BG259_RS11175	COG2964	Protein conserved in bacteria
BG259_RS11180	COG0545	Peptidyl-prolyl cis-trans isomerase
BG259_RS11195	COG1446	asparaginase
BG259_RS11200	COG1047	Peptidyl-prolyl cis-trans
BG259_RS11215	COG2249	NAD(P)H dehydrogenase (quinone) activity
BG259_RS11220	COG0488	(ABC) transporter
BG259_RS11230	COG0429	hydrolase of the alpha beta-hydrolase fold
BG259_RS11240	COG3954	Phosphoribulokinase
BG259_RS11245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BG259_RS11265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BG259_RS11270	COG0512	Glutamine amidotransferase of anthranilate synthase
BG259_RS11295	COG0546	phosphoglycolate phosphatase activity
BG259_RS11300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BG259_RS11305	COG0557	exoribonuclease II activity
BG259_RS11315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BG259_RS11315	COG1017	nitric oxide dioxygenase activity
BG259_RS11320	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BG259_RS11325	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BG259_RS11330	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BG259_RS11335	COG0330	HflC and HflK could
BG259_RS11340	COG0330	HflC and HflK could
BG259_RS11345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BG259_RS11360	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BG259_RS11370	COG0802	atpase or kinase
BG259_RS11375	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BG259_RS11445	COG1162	GTPase activity
BG259_RS11455	COG0471	metal ion transport
BG259_RS11470	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BG259_RS11475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BG259_RS11480	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BG259_RS11490	COG1045	serine acetyltransferase
BG259_RS11495	COG4942	peptidase
BG259_RS11520	COG1053	succinate dehydrogenase
BG259_RS11525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BG259_RS11555	COG1509	lysine 2,3-aminomutase activity
BG259_RS11580	COG0534	Mate efflux family protein
BG259_RS11590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BG259_RS11595	COG3678	ATP-independent chaperone mediated protein folding
BG259_RS11600	COG0745	RESPONSE REGULATOR receiver
BG259_RS11605	COG2205	protein histidine kinase activity
BG259_RS11610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BG259_RS11615	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BG259_RS11620	COG3030	protein affecting phage T7 exclusion by the F plasmid
BG259_RS11625	COG1027	Aspartate ammonia-lyase
BG259_RS11630	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BG259_RS11635	COG4232	protein-disulfide reductase activity
BG259_RS11645	COG2095	MarC family integral membrane protein
BG259_RS11655	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG259_RS11675	COG0784	Response regulator, receiver
BG259_RS11675	COG2205	protein histidine kinase activity
BG259_RS11675	COG2198	Histidine kinase
BG259_RS11680	COG2814	Major facilitator Superfamily
BG259_RS11695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BG259_RS11700	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BG259_RS11705	COG0511	ligase activity, forming carbon-carbon bonds
BG259_RS11710	COG0439	Biotin carboxylase
BG259_RS11720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BG259_RS11725	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BG259_RS11730	COG2199	diguanylate cyclase activity
BG259_RS11755	COG1982	Orn Lys Arg decarboxylase major
BG259_RS11760	COG0531	amino acid
BG259_RS11770	COG3710	Transcriptional regulator
BG259_RS11775	COG0789	Transcriptional regulator
BG259_RS11790	COG0151	Belongs to the GarS family
BG259_RS11805	COG1253	flavin adenine dinucleotide binding
BG259_RS11810	COG3068	Protein conserved in bacteria
BG259_RS11820	COG1573	uracil-dna glycosylase
BG259_RS11840	COG2816	NAD+ diphosphatase activity
BG259_RS11845	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BG259_RS11865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BG259_RS11880	COG0250	Participates in transcription elongation, termination and antitermination
BG259_RS11885	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BG259_RS11925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BG259_RS11935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BG259_RS12070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG259_RS12075	COG0534	Mate efflux family protein
BG259_RS12095	COG2937	Belongs to the GPAT DAPAT family
BG259_RS12105	COG3161	chorismate lyase activity
BG259_RS12110	COG1580	Controls the rotational direction of flagella during chemotaxis
BG259_RS12115	COG0705	Rhomboid family
BG259_RS12130	COG2177	Part of the ABC transporter FtsEX involved in
BG259_RS12135	COG2884	Cell division ATP-binding protein ftsE
BG259_RS12140	COG0552	protein localization to endoplasmic reticulum
BG259_RS12145	COG0742	ribosomal rna small subunit methyltransferase
BG259_RS12155	COG2095	MarC family integral membrane protein
BG259_RS12200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BG259_RS12205	COG0640	Transcriptional regulator
BG259_RS12210	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BG259_RS12215	COG1280	lysine exporter protein (LysE YggA)
BG259_RS12220	COG2267	carboxylic ester hydrolase activity
BG259_RS12225	COG0561	phosphatase activity
BG259_RS12240	COG3148	PFAM DTW domain containing protein
BG259_RS12245	COG2200	EAL domain
BG259_RS12245	COG2199	diguanylate cyclase activity
BG259_RS12245	COG3287	FIST C domain
BG259_RS12250	COG1011	Hydrolase
BG259_RS12270	COG0019	diaminopimelate decarboxylase activity
BG259_RS12285	COG3072	Adenylate cyclase
BG259_RS12295	COG1587	Uroporphyrinogen-III synthase
BG259_RS12300	COG2959	enzyme of heme biosynthesis
BG259_RS12305	COG3071	HemY protein
BG259_RS12345	COG0633	Ferredoxin
BG259_RS12350	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BG259_RS12365	COG3118	belongs to the thioredoxin family
BG259_RS12380	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BG259_RS12390	COG0514	ATP-dependent DNA helicase (RecQ)
BG259_RS12395	COG2962	Rard protein
BG259_RS12405	COG1280	lysine exporter protein (LysE YggA)
BG259_RS12410	COG0405	Gamma-glutamyltransferase
BG259_RS12420	COG0210	DNA helicase
BG259_RS12430	COG3220	belongs to the UPF0276 family
BG259_RS12450	COG2814	Major facilitator Superfamily
BG259_RS12460	COG0006	proline dipeptidase activity
BG259_RS12460	COG0006	proline dipeptidase activity
BG259_RS12475	COG2104	thiamine diphosphate biosynthetic process
BG259_RS12480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BG259_RS12500	COG2132	Multicopper oxidase
BG259_RS12550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BG259_RS12555	COG1739	Uncharacterized protein family UPF0029
BG259_RS12565	COG0183	Belongs to the thiolase family
BG259_RS12570	COG0604	alcohol dehydrogenase
BG259_RS12585	COG0425	Belongs to the sulfur carrier protein TusA family
BG259_RS12595	COG2119	membrane
BG259_RS12610	COG0366	Alpha amylase catalytic
BG259_RS12615	COG3977	Valine--pyruvate aminotransferase
BG259_RS12620	COG0071	Belongs to the small heat shock protein (HSP20) family
BG259_RS12625	COG0187	DNA topoisomerase II activity
BG259_RS12635	COG0592	DNA-directed DNA polymerase activity
BG259_RS12655	COG1126	abc transporter atp-binding protein
BG259_RS12720	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BG259_RS12730	COG3645	SOS response
BG259_RS12770	COG1395	domain, Protein
BG259_RS12785	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BG259_RS12790	COG0445	tRNA wobble uridine modification
BG259_RS12800	COG1192	Involved in chromosome partitioning
BG259_RS12805	COG1475	DNA binding
BG259_RS12810	COG3312	ion transport
BG259_RS12815	COG0356	it plays a direct role in the translocation of protons across the membrane
BG259_RS12840	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BG259_RS12850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BG259_RS12860	COG0765	amino acid transport
BG259_RS12870	COG2814	Major facilitator Superfamily
BG259_RS12875	COG0583	DNA-binding transcription factor activity
BG259_RS12885	COG0129	dihydroxy-acid dehydratase activity
BG259_RS12890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BG259_RS12895	COG3978	acetolactate synthase activity
BG259_RS12905	COG0606	chelatase, subunit chli
BG259_RS12910	COG3706	GGDEF domain
BG259_RS12920	COG0204	Acyl-transferase
BG259_RS12925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BG259_RS12930	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BG259_RS12935	COG4974	Belongs to the 'phage' integrase family
BG259_RS13040	COG3084	Protein conserved in bacteria
BG259_RS13045	COG4326	sporulation control protein
BG259_RS13050	COG1272	protein, Hemolysin III
BG259_RS13060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BG259_RS13065	COG0569	domain protein
BG259_RS13070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BG259_RS13070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BG259_RS13080	COG0242	peptide deformylase activity
BG259_RS13090	COG0758	DNA mediated transformation
BG259_RS13100	COG0551	DNA topoisomerase type I activity
BG259_RS13105	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BG259_RS13110	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BG259_RS13125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BG259_RS13135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BG259_RS13175	COG0583	DNA-binding transcription factor activity
BG259_RS13180	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BG259_RS13185	COG2960	long-chain fatty acid transporting porin activity
BG259_RS13190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG259_RS13195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BG259_RS13200	COG1309	transcriptional regulator
BG259_RS13250	COG4172	Belongs to the ABC transporter superfamily
BG259_RS13255	COG0747	negative chemotaxis
BG259_RS13260	COG0601	transmembrane transport
BG259_RS13265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG259_RS13300	COG1609	Transcriptional regulator
BG259_RS13305	COG0583	DNA-binding transcription factor activity
BG259_RS13310	COG2076	Multidrug Resistance protein
BG259_RS13320	COG0129	dihydroxy-acid dehydratase activity
BG259_RS13325	COG3265	gluconokinase activity
BG259_RS13330	COG2610	gluconate transmembrane transporter activity
BG259_RS13335	COG0800	Aldolase
BG259_RS13340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG259_RS13355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BG259_RS13370	COG1522	sequence-specific DNA binding
BG259_RS13375	COG5002	protein histidine kinase activity
BG259_RS13375	COG5001	Diguanylate cyclase
BG259_RS13395	COG0589	response to stress
BG259_RS13405	COG1528	Iron-storage protein
BG259_RS13415	COG2081	HI0933 family
BG259_RS13435	COG1322	Protein conserved in bacteria
BG259_RS13445	COG3165	ubiquinone biosynthetic process from chorismate
BG259_RS13460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BG259_RS13465	COG0805	protein transport
BG259_RS13470	COG0084	hydrolase, TatD family'
BG259_RS13490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BG259_RS13490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BG259_RS13495	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BG259_RS13525	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BG259_RS13535	COG2204	response regulator
BG259_RS13540	COG3852	Histidine kinase
BG259_RS13550	COG0174	glutamine synthetase
BG259_RS13560	COG1217	gtp-binding protein TYPA
BG259_RS13580	COG1490	D-aminoacyl-tRNA deacylase activity
BG259_RS13585	COG0456	acetyltransferase
BG259_RS13605	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BG259_RS13610	COG3031	protein transport across the cell outer membrane
BG259_RS13620	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BG259_RS13625	COG1459	type II secretion system
BG259_RS13630	COG2165	general secretion pathway protein
BG259_RS13635	COG2165	general secretion pathway protein
BG259_RS13640	COG2165	general secretion pathway protein
BG259_RS13645	COG4795	General secretion pathway protein
BG259_RS13650	COG3156	type II secretion system protein K
BG259_RS13655	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BG259_RS13660	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BG259_RS13670	COG1218	3'(2'),5'-bisphosphate nucleotidase
BG259_RS13675	COG0494	nUDIX hydrolase
BG259_RS13685	COG1040	competence protein
BG259_RS13700	COG2183	response to ionizing radiation
BG259_RS13710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BG259_RS13725	COG2233	PERMEase
BG259_RS13735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BG259_RS13740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BG259_RS13745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BG259_RS13750	COG1758	RNA polymerase activity
BG259_RS13755	COG0194	GDP metabolic process
BG259_RS13770	COG0848	biopolymer transport protein
BG259_RS13775	COG0811	peptide transport
BG259_RS13795	COG4174	ABC transporter (Permease)
BG259_RS13800	COG4239	(ABC) transporter, permease
BG259_RS13805	COG0747	negative chemotaxis
BG259_RS13810	COG0444	Belongs to the ABC transporter superfamily
BG259_RS13815	COG4608	Belongs to the ABC transporter superfamily
BG259_RS13840	COG0745	RESPONSE REGULATOR receiver
BG259_RS13845	COG1561	YicC-like family, N-terminal region
BG259_RS13850	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BG259_RS13855	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BG259_RS13860	COG1560	Kdo2-lipid A biosynthetic process
BG259_RS13870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BG259_RS13875	COG0840	transmembrane signaling receptor activity
BG259_RS13895	COG2194	sulfuric ester hydrolase activity
BG259_RS13910	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BG259_RS13925	COG0463	Glycosyl transferase, family 2
BG259_RS13930	COG0859	PFAM glycosyl transferase family 9
BG259_RS13935	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BG259_RS13940	COG3642	lipopolysaccharide core region biosynthetic process
BG259_RS13960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BG259_RS13970	COG1028	Short-chain dehydrogenase reductase Sdr
BG259_RS13985	COG1021	2,3-dihydroxybenzoate-AMP ligase
BG259_RS13990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BG259_RS14000	COG1086	Polysaccharide biosynthesis protein
BG259_RS14005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BG259_RS14010	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BG259_RS14015	COG2089	acid synthase
BG259_RS14025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BG259_RS14040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BG259_RS14050	COG1028	Short-chain dehydrogenase reductase Sdr
BG259_RS14065	COG1519	Transferase
BG259_RS14070	COG0859	PFAM glycosyl transferase family 9
BG259_RS14075	COG1560	Kdo2-lipid A biosynthetic process
BG259_RS14085	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BG259_RS14150	COG1216	Glycosyl transferase, family 2
BG259_RS14160	COG0438	transferase activity, transferring glycosyl groups
BG259_RS14160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BG259_RS14165	COG0438	transferase activity, transferring glycosyl groups
BG259_RS14170	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BG259_RS14175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BG259_RS14195	COG1482	cell wall glycoprotein biosynthetic process
BG259_RS14210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BG259_RS14225	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BG259_RS14230	COG0149	triose-phosphate isomerase activity
BG259_RS14260	COG1494	fructose-1,6-bisphosphatase
BG259_RS14275	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BG259_RS14280	COG1575	Belongs to the MenA family. Type 1 subfamily
BG259_RS14300	COG1609	Transcriptional regulator
BG259_RS14305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BG259_RS14310	COG0254	rRNA binding
BG259_RS14325	COG0088	Forms part of the polypeptide exit tunnel
BG259_RS14345	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BG259_RS14395	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BG259_RS14410	COG1841	ribosomal large subunit assembly
BG259_RS14415	COG0200	Binds to the 23S rRNA
BG259_RS14420	COG0201	protein transport
BG259_RS14425	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BG259_RS14430	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BG259_RS14435	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BG259_RS14445	COG0202	RNA polymerase activity
BG259_RS14450	COG0203	ribosomal protein L17
BG259_RS14460	COG0545	Peptidyl-prolyl cis-trans isomerase
BG259_RS14475	COG2153	protein acetylation
BG259_RS14480	COG0513	Belongs to the DEAD box helicase family
BG259_RS14490	COG0737	Belongs to the 5'-nucleotidase family
BG259_RS14495	COG1648	precorrin-2 dehydrogenase activity
BG259_RS14495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BG259_RS14510	COG0471	metal ion transport
BG259_RS14510	COG3273	potassium ion transport
BG259_RS14515	COG0529	Catalyzes the synthesis of activated sulfate
BG259_RS14535	COG1136	(ABC) transporter
BG259_RS14550	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BG259_RS14560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BG259_RS14565	COG0729	surface antigen
BG259_RS14575	COG2105	PFAM AIG2 family protein
BG259_RS14585	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BG259_RS14595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BG259_RS14600	COG0163	prenyltransferase activity
BG259_RS14605	COG4143	(ABC) transporter
BG259_RS14610	COG1178	ABC-type Fe3 transport system permease component
BG259_RS14615	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BG259_RS14650	COG0142	geranyltranstransferase activity
BG259_RS14655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BG259_RS14665	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BG259_RS14670	COG2966	Psort location CytoplasmicMembrane, score
BG259_RS14675	COG3610	response to peptide
BG259_RS14695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BG259_RS14700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BG259_RS14705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BG259_RS14710	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BG259_RS14715	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BG259_RS14735	COG0473	3-isopropylmalate dehydrogenase activity
BG259_RS14740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BG259_RS14755	COG0671	phosphoesterase, PA-phosphatase related
BG259_RS14765	COG0583	DNA-binding transcription factor activity
BG259_RS14770	COG1022	Amp-dependent synthetase and ligase
BG259_RS14775	COG0028	Belongs to the TPP enzyme family
BG259_RS14780	COG0440	acetolactate synthase activity
BG259_RS14795	COG0469	pyruvate kinase activity
BG259_RS14800	COG1349	DNA-binding transcription factor activity
BG259_RS14805	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BG259_RS14825	COG5002	protein histidine kinase activity
BG259_RS14830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BG259_RS14835	COG3722	fumarate hydratase activity
BG259_RS14845	COG2213	PTS system mannitol-specific
BG259_RS14845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG259_RS14880	COG0358	DNA primase activity
BG259_RS14885	COG1610	YqeY-like protein
BG259_RS14890	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BG259_RS14895	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BG259_RS14900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BG259_RS14910	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BG259_RS14915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BG259_RS14930	COG3267	Type II secretory pathway component ExeA
BG259_RS14930	COG3409	Peptidoglycan-binding domain 1 protein
BG259_RS14940	COG4991	sh3 domain protein
BG259_RS14945	COG0306	phosphate transporter
BG259_RS14950	COG1392	Phosphate transport regulator
BG259_RS14955	COG3025	triphosphatase activity
BG259_RS14960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BG259_RS14970	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BG259_RS14980	COG1538	Outer membrane efflux protein
BG259_RS14985	COG0494	nUDIX hydrolase
BG259_RS14990	COG3151	Protein conserved in bacteria
BG259_RS15000	COG3150	esterase
BG259_RS15010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BG259_RS15015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BG259_RS15030	COG3105	Protein conserved in bacteria
BG259_RS15035	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BG259_RS15050	COG0723	plastoquinol--plastocyanin reductase activity
BG259_RS15055	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BG259_RS15060	COG2857	Cytochrome c1
BG259_RS15065	COG0625	glutathione transferase activity
BG259_RS15070	COG2969	positive regulation of protein catabolic process
BG259_RS15075	COG2823	Periplasmic or secreted lipoprotein
BG259_RS15080	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BG259_RS15095	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BG259_RS15110	COG3116	cell division
BG259_RS15115	COG0768	penicillin binding
BG259_RS15120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BG259_RS15125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BG259_RS15140	COG0772	Belongs to the SEDS family
BG259_RS15155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BG259_RS15160	COG0849	cell division
BG259_RS15165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BG259_RS15180	COG0494	nUDIX hydrolase
BG259_RS15190	COG0505	Belongs to the CarA family
BG259_RS15195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BG259_RS15215	COG0730	response to heat
BG259_RS15220	COG0583	DNA-binding transcription factor activity
BG259_RS15225	COG2860	membrane
BG259_RS15250	COG0493	'glutamate synthase
BG259_RS15255	COG0069	glutamate synthase activity
BG259_RS15255	COG0067	glutamate synthase
BG259_RS15255	COG0070	glutamate synthase
BG259_RS15265	COG0067	glutamate synthase
BG259_RS15265	COG0069	glutamate synthase activity
BG259_RS15265	COG0070	glutamate synthase
BG259_RS15270	COG1242	4 iron, 4 sulfur cluster binding
BG259_RS15275	COG2203	Gaf domain
BG259_RS15275	COG3706	GGDEF domain
BG259_RS15275	COG4251	negative regulation of phosphorylation
BG259_RS15275	COG5001	Diguanylate cyclase
BG259_RS15285	COG5002	protein histidine kinase activity
BG259_RS15285	COG2198	Histidine kinase
BG259_RS15285	COG0784	Response regulator, receiver
BG259_RS15295	COG0745	RESPONSE REGULATOR receiver
BG259_RS15305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BG259_RS15320	COG0083	homoserine kinase activity
BG259_RS15325	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BG259_RS15330	COG0431	NADPH-dependent FMN reductase
BG259_RS15360	COG1115	amino acid carrier protein
BG259_RS15365	COG3022	response to hydroperoxide
BG259_RS15375	COG0513	Belongs to the DEAD box helicase family
BG259_RS15390	COG0716	FMN binding
BG259_RS15395	COG4974	Belongs to the 'phage' integrase family
BG259_RS15400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BG259_RS15405	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BG259_RS15430	COG0667	Aldo Keto reductase
BG259_RS15450	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
BG259_RS15455	COG0730	response to heat
BG259_RS15470	COG1283	sodium-dependent phosphate transmembrane transporter activity
BG259_RS15475	COG0583	DNA-binding transcription factor activity
BG259_RS15480	COG0640	Transcriptional regulator
BG259_RS15485	COG0268	Binds directly to 16S ribosomal RNA
BG259_RS15490	COG0728	peptidoglycan biosynthetic process
BG259_RS15495	COG0196	riboflavin kinase activity
BG259_RS15510	COG1047	Peptidyl-prolyl cis-trans
BG259_RS15515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BG259_RS15520	COG3279	Response regulator of the LytR AlgR family
BG259_RS15525	COG3275	phosphorelay sensor kinase activity
BG259_RS15530	COG1966	Carbon starvation protein
BG259_RS15550	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BG259_RS15560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BG259_RS15565	COG0287	Prephenate dehydrogenase
BG259_RS15565	COG1605	Chorismate mutase
BG259_RS15570	COG0739	heme binding
BG259_RS15580	COG0488	(ABC) transporter
BG259_RS15595	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BG259_RS15600	COG1605	Chorismate mutase
BG259_RS15600	COG0077	Prephenate dehydratase
BG259_RS15605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BG259_RS15610	COG0741	lytic transglycosylase activity
BG259_RS15615	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BG259_RS15620	COG0564	pseudouridine synthase activity
BG259_RS15625	COG1496	oxidoreductase activity
BG259_RS15630	COG0542	response to heat
BG259_RS15690	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BG259_RS15695	COG0826	peptidase U32
BG259_RS15705	COG0745	RESPONSE REGULATOR receiver
BG259_RS15710	COG5002	protein histidine kinase activity
BG259_RS15720	COG0248	Ppx GppA phosphatase
BG259_RS15725	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BG259_RS15730	COG0573	inorganic phosphate transmembrane transporter activity
BG259_RS15735	COG0581	inorganic phosphate transmembrane transporter activity
BG259_RS15740	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BG259_RS15745	COG0704	Plays a role in the regulation of phosphate uptake
BG259_RS15775	COG0450	alkyl hydroperoxide reductase
BG259_RS15780	COG0583	DNA-binding transcription factor activity
BG259_RS15785	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BG259_RS15795	COG0517	IMP dehydrogenase activity
BG259_RS15820	COG1862	Preprotein translocase
BG259_RS15825	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BG259_RS15830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BG259_RS15845	COG0483	inositol monophosphate 1-phosphatase activity
BG259_RS15850	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BG259_RS15865	COG0822	iron-sulfur transferase activity
BG259_RS15870	COG0316	Belongs to the HesB IscA family
BG259_RS15885	COG0633	Ferredoxin
BG259_RS15890	COG2975	iron-sulfur cluster assembly
BG259_RS15925	COG2976	Protein conserved in bacteria
BG259_RS15930	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BG259_RS15945	COG2203	Gaf domain
BG259_RS15945	COG2199	diguanylate cyclase activity
BG259_RS15960	COG0517	IMP dehydrogenase activity
BG259_RS15960	COG0516	GMP reductase activity
BG259_RS15970	COG1757	Na H antiporter
BG259_RS15980	COG1584	GPR1 FUN34 yaaH family protein
BG259_RS15985	COG1115	amino acid carrier protein
BG259_RS15995	COG0583	DNA-binding transcription factor activity
BG259_RS16000	COG0668	transmembrane transport
BG259_RS16005	COG2873	o-acetylhomoserine
BG259_RS16010	COG0316	Belongs to the HesB IscA family
BG259_RS16015	COG0719	Fe-S assembly protein
BG259_RS16020	COG0396	ATPase activity
BG259_RS16025	COG0719	Fe-S assembly protein
BG259_RS16045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BG259_RS16065	COG1289	transmembrane transporter activity
BG259_RS16070	COG0583	DNA-binding transcription factor activity
BG259_RS16095	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BG259_RS16115	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BG259_RS16135	COG2867	negative regulation of translational initiation
BG259_RS16140	COG2914	Belongs to the UPF0125 (RnfH) family
BG259_RS16145	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BG259_RS16150	COG0497	DNA recombination
BG259_RS16170	COG1301	dicarboxylic acid transport
BG259_RS16195	COG4969	Belongs to the N-Me-Phe pilin family
BG259_RS16215	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BG259_RS16220	COG0590	tRNA wobble adenosine to inosine editing
BG259_RS16230	COG0047	phosphoribosylformylglycinamidine synthase activity
BG259_RS16230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BG259_RS16260	COG2195	Cleaves the N-terminal amino acid of tripeptides
BG259_RS16265	COG2252	PERMEase
BG259_RS16270	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BG259_RS16275	COG1073	alpha beta
BG259_RS16290	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BG259_RS16295	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BG259_RS16300	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BG259_RS16300	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BG259_RS16325	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BG259_RS16330	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BG259_RS16340	COG0142	geranyltranstransferase activity
BG259_RS16350	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BG259_RS16365	COG0583	DNA-binding transcription factor activity
BG259_RS16375	COG2363	Small membrane protein
BG259_RS16395	COG1611	Belongs to the LOG family
BG259_RS16420	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BG259_RS16425	COG0737	Belongs to the 5'-nucleotidase family
BG259_RS16435	COG1464	Belongs to the NlpA lipoprotein family
BG259_RS16440	COG2011	ABC-type metal ion transport system permease component
BG259_RS16445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BG259_RS16450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BG259_RS16460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG259_RS16460	COG1263	PTS System
BG259_RS16465	COG0366	Alpha amylase catalytic
BG259_RS16480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG259_RS16485	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BG259_RS16505	COG1686	Belongs to the peptidase S11 family
BG259_RS16510	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BG259_RS16515	COG0772	Belongs to the SEDS family
BG259_RS16520	COG0768	penicillin binding
BG259_RS16530	COG0799	negative regulation of ribosome biogenesis
BG259_RS16535	COG1466	dna polymerase III delta subunit
BG259_RS16540	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BG259_RS16550	COG2888	peptidyl-tyrosine sulfation
BG259_RS16555	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BG259_RS16560	COG4535	Mg2 and Co2 transporter CorC
BG259_RS16570	COG1702	phosphate starvation-inducible protein PhoH
BG259_RS16580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BG259_RS16705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BG259_RS16730	COG2890	protein-(glutamine-N5) methyltransferase activity
BG259_RS16735	COG3094	Invasion gene expression up-regulator, SirB
BG259_RS16740	COG2912	Transglutaminase-like superfamily
BG259_RS16745	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BG259_RS16750	COG0737	Belongs to the 5'-nucleotidase family
BG259_RS16755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BG259_RS16760	COG1187	pseudouridine synthase activity
BG259_RS16765	COG2840	Smr protein MutS2
BG259_RS16810	COG2608	mercury ion transmembrane transporter activity
BG259_RS16810	COG2217	Heavy metal translocating P-type atpase
BG259_RS16820	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BG259_RS16880	COG0784	Response regulator, receiver
BG259_RS16880	COG0835	chemotaxis
BG259_RS16885	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BG259_RS16890	COG1815	bacterial-type flagellum-dependent cell motility
BG259_RS16895	COG1558	bacterial-type flagellum-dependent cell motility
BG259_RS16910	COG4787	bacterial-type flagellum-dependent cell motility
BG259_RS16920	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BG259_RS16925	COG1706	bacterial-type flagellum-dependent cell motility
BG259_RS16930	COG3951	Flagellar rod assembly protein muramidase FlgJ
BG259_RS16930	COG1705	Flagellar rod assembly protein muramidase FlgJ
BG259_RS16945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BG259_RS16950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BG259_RS16955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BG259_RS16960	COG2190	(PTS) system
BG259_RS16965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BG259_RS16970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BG259_RS16980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BG259_RS16985	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BG259_RS17015	COG0330	HflC and HflK could
BG259_RS17020	COG3118	belongs to the thioredoxin family
BG259_RS17030	COG0300	oxidoreductase activity
BG259_RS17035	COG1090	epimerase
BG259_RS17065	COG0622	Phosphoesterase
BG259_RS17085	COG3710	Transcriptional regulator
BG259_RS17090	COG0326	Molecular chaperone. Has ATPase activity
BG259_RS17100	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BG259_RS17105	COG3104	oligopeptide transport
BG259_RS17115	COG0367	asparagine synthase
BG259_RS17120	COG4651	solute:proton antiporter activity
BG259_RS17120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BG259_RS17125	COG1846	Transcriptional regulator
BG259_RS17125	COG1940	carbohydrate kinase activity
BG259_RS17130	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BG259_RS17135	COG2190	(PTS) system
BG259_RS17135	COG1263	PTS System
BG259_RS17135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BG259_RS17185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BG259_RS17345	COG0318	PFAM AMP-dependent synthetase and ligase
BG259_RS17605	COG0513	Belongs to the DEAD box helicase family
BG259_RS17825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BG259_RS18465	COG1882	Formate acetyltransferase
BG259_RS18870	COG4771	TonB-dependent receptor
BG259_RS19050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BG259_RS19190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BG259_RS19390	COG2116	formate transmembrane transporter activity
BG259_RS19570	COG1151	hydroxylamine reductase activity
BG259_RS19575	COG1151	hydroxylamine reductase activity
BG259_RS20955	COG3148	PFAM DTW domain containing protein
BG259_RS21265	COG0488	(ABC) transporter
BG259_RS21295	COG2902	Dehydrogenase
BG259_RS21355	COG3008	intermembrane lipid transfer
BG259_RS21360	COG3008	intermembrane lipid transfer
BG259_RS21700	COG4934	collagen metabolic process
BG259_RS21720	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BG259_RS21780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BG259_RS22000	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BG259_RS22155	COG3938	Belongs to the proline racemase family
BG259_RS22945	COG2989	Protein conserved in bacteria
BG259_RS22955	COG2989	Protein conserved in bacteria
BG259_RS23040	COG3301	Polysulphide reductase, NrfD
BG259_RS23125	COG0076	glutamate decarboxylase activity
BG259_RS23310	COG5001	Diguanylate cyclase
BG259_RS23310	COG3300	MHYT domain
BG259_RS23340	COG0446	pyridine nucleotide-disulphide oxidoreductase
BG259_RS23880	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BG259_RS23885	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BG259_RS23910	COG0366	Alpha amylase catalytic
BG259_RS23985	COG4166	transmembrane transport
BG259_RS24130	COG3451	type IV secretory pathway VirB4
BG259_RS24485	COG0814	amino acid
BG259_RS24585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BG259_RS24630	COG2860	membrane
BG259_RS24770	COG2201	protein-glutamate methylesterase activity
BG259_RS24815	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BG259_RS24930	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BG259_RS25090	COG1960	acyl-CoA dehydrogenase activity
BG259_RS25510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BG259_RS25510	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BG259_RS25535	COG1074	ATP-dependent DNA helicase activity
BG259_RS25805	COG4964	Belongs to the GSP D family
BG259_RS26070	COG2027	D-alanyl-D-alanine carboxypeptidase
BG259_RS26380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BG259_RS26390	COG1459	type II secretion system
BG259_RS26425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BG259_RS26465	COG0612	Peptidase, M16
BG259_RS26605	COG0504	CTP synthase activity
BG259_RS27300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BG259_RS27305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BG259_RS27555	COG0318	PFAM AMP-dependent synthetase and ligase
BG259_RS27590	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BG259_RS28010	COG1121	(ABC) transporter
BG259_RS28130	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BG259_RS28465	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BG259_RS28525	COG1199	ATP-dependent helicase activity
BG259_RS28635	COG1028	Short-chain dehydrogenase reductase Sdr
BG259_RS28640	COG1028	Short-chain dehydrogenase reductase Sdr