locus-tag	class	description
F9277_RS00035	COG2199	diguanylate cyclase activity
F9277_RS00040	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
F9277_RS00045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F9277_RS00060	COG0439	Biotin carboxylase
F9277_RS00065	COG0511	ligase activity, forming carbon-carbon bonds
F9277_RS00070	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F9277_RS00075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9277_RS00090	COG2814	Major facilitator Superfamily
F9277_RS00095	COG0784	Response regulator, receiver
F9277_RS00095	COG2198	Histidine kinase
F9277_RS00095	COG2205	protein histidine kinase activity
F9277_RS00115	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9277_RS00125	COG2095	MarC family integral membrane protein
F9277_RS00135	COG4232	protein-disulfide reductase activity
F9277_RS00140	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F9277_RS00145	COG1027	Aspartate ammonia-lyase
F9277_RS00150	COG3030	protein affecting phage T7 exclusion by the F plasmid
F9277_RS00155	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F9277_RS00160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F9277_RS00165	COG2205	protein histidine kinase activity
F9277_RS00170	COG0745	RESPONSE REGULATOR receiver
F9277_RS00175	COG3678	ATP-independent chaperone mediated protein folding
F9277_RS00180	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F9277_RS00190	COG0534	Mate efflux family protein
F9277_RS00215	COG1509	lysine 2,3-aminomutase activity
F9277_RS00245	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F9277_RS00250	COG1053	succinate dehydrogenase
F9277_RS00275	COG4942	peptidase
F9277_RS00280	COG1045	serine acetyltransferase
F9277_RS00290	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
F9277_RS00295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F9277_RS00300	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
F9277_RS00315	COG0471	metal ion transport
F9277_RS00325	COG1162	GTPase activity
F9277_RS00395	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F9277_RS00400	COG0802	atpase or kinase
F9277_RS00410	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F9277_RS00425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F9277_RS00430	COG0330	HflC and HflK could
F9277_RS00435	COG0330	HflC and HflK could
F9277_RS00440	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
F9277_RS00445	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F9277_RS00455	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
F9277_RS00460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F9277_RS00460	COG1017	nitric oxide dioxygenase activity
F9277_RS00470	COG0557	exoribonuclease II activity
F9277_RS00475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9277_RS00480	COG0546	phosphoglycolate phosphatase activity
F9277_RS00505	COG0512	Glutamine amidotransferase of anthranilate synthase
F9277_RS00510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F9277_RS00530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F9277_RS00535	COG3954	Phosphoribulokinase
F9277_RS00545	COG0429	hydrolase of the alpha beta-hydrolase fold
F9277_RS00555	COG0488	(ABC) transporter
F9277_RS00565	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9277_RS00580	COG1047	Peptidyl-prolyl cis-trans
F9277_RS00590	COG1446	asparaginase
F9277_RS00605	COG0545	Peptidyl-prolyl cis-trans isomerase
F9277_RS00610	COG2964	Protein conserved in bacteria
F9277_RS00615	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F9277_RS00620	COG2923	Belongs to the DsrF TusC family
F9277_RS00625	COG2168	tRNA wobble position uridine thiolation
F9277_RS00640	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F9277_RS00650	COG2906	2 iron, 2 sulfur cluster binding
F9277_RS00660	COG0281	malic enzyme
F9277_RS00670	COG0626	cystathionine gamma-synthase activity
F9277_RS00675	COG0527	aspartate kinase activity
F9277_RS00675	COG0460	homoserine dehydrogenase
F9277_RS00680	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F9277_RS00690	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
F9277_RS00700	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F9277_RS00715	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F9277_RS00715	COG0165	Argininosuccinate lyase
F9277_RS00730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9277_RS00735	COG0678	peroxiredoxin activity
F9277_RS00735	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F9277_RS00745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F9277_RS00790	COG0338	D12 class N6 adenine-specific DNA methyltransferase
F9277_RS00805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F9277_RS00810	COG0360	Binds together with S18 to 16S ribosomal RNA
F9277_RS00830	COG0305	Participates in initiation and elongation during chromosome replication
F9277_RS00835	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F9277_RS00845	COG0432	Pfam Uncharacterised protein family UPF0047
F9277_RS00860	COG0735	belongs to the Fur family
F9277_RS00900	COG0582	viral genome integration into host DNA
F9277_RS00905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F9277_RS00925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F9277_RS01000	COG1410	methionine synthase
F9277_RS01000	COG0646	methionine synthase
F9277_RS01005	COG0527	aspartate kinase activity
F9277_RS01015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F9277_RS01025	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F9277_RS01040	COG0629	single-stranded DNA binding
F9277_RS01045	COG2199	diguanylate cyclase activity
F9277_RS01045	COG2200	EAL domain
F9277_RS01070	COG3267	Type II secretory pathway component ExeA
F9277_RS01070	COG3409	Peptidoglycan-binding domain 1 protein
F9277_RS01080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F9277_RS01085	COG1459	type II secretion system
F9277_RS01095	COG2165	general secretion pathway protein
F9277_RS01130	COG1077	Cell shape determining protein MreB Mrl
F9277_RS01135	COG1792	Involved in formation and maintenance of cell shape
F9277_RS01140	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F9277_RS01145	COG0424	maF-like protein
F9277_RS01155	COG3164	Protein of unknown function
F9277_RS01160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F9277_RS01165	COG0312	modulator of DNA gyrase
F9277_RS01170	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
F9277_RS01185	COG0564	pseudouridine synthase activity
F9277_RS01190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F9277_RS01200	COG0312	modulator of DNA gyrase
F9277_RS01205	COG2239	Acts as a magnesium transporter
F9277_RS01210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9277_RS01220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9277_RS01225	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F9277_RS01235	COG1137	ATPase activity
F9277_RS01240	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F9277_RS01250	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F9277_RS01250	COG0517	IMP dehydrogenase activity
F9277_RS01260	COG1127	ABC transporter
F9277_RS01265	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F9277_RS01270	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F9277_RS01275	COG2854	intermembrane phospholipid transfer
F9277_RS01285	COG5007	Belongs to the BolA IbaG family
F9277_RS01295	COG0204	Acyl-transferase
F9277_RS01300	COG0251	oxidation-reduction process
F9277_RS01345	COG0456	acetyltransferase
F9277_RS01355	COG0525	valine-tRNA ligase activity
F9277_RS01360	COG2927	DNA polymerase III (CHI subunit)
F9277_RS01370	COG0795	lipopolysaccharide-transporting ATPase activity
F9277_RS01375	COG0795	lipopolysaccharide-transporting ATPase activity
F9277_RS01385	COG1028	Short-chain dehydrogenase reductase Sdr
F9277_RS01405	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F9277_RS01415	COG1447	Phosphotransferase system cellobiose-specific component IIA
F9277_RS01420	COG1486	melibiose metabolic process
F9277_RS01435	COG3437	response regulator, receiver
F9277_RS01485	COG1012	belongs to the aldehyde dehydrogenase family
F9277_RS01585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F9277_RS01590	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F9277_RS01605	COG0762	integral membrane protein
F9277_RS01610	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F9277_RS01615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F9277_RS01630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F9277_RS01635	COG1678	Uncharacterized ACR, COG1678
F9277_RS01640	COG0189	ligase activity
F9277_RS01645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F9277_RS01650	COG2356	endonuclease I
F9277_RS01675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F9277_RS01695	COG0191	fructose-bisphosphate aldolase activity
F9277_RS01700	COG0668	transmembrane transport
F9277_RS01715	COG0583	DNA-binding transcription factor activity
F9277_RS01725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F9277_RS01735	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F9277_RS01745	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
F9277_RS01760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9277_RS01765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9277_RS01785	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F9277_RS01795	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F9277_RS01805	COG1595	DNA-templated transcription, initiation
F9277_RS01820	COG3086	response to oxidative stress
F9277_RS01840	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F9277_RS01845	COG1381	Involved in DNA repair and RecF pathway recombination
F9277_RS01850	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F9277_RS01875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F9277_RS01880	COG3956	TIGRFAM MazG family protein
F9277_RS01890	COG0148	phosphopyruvate hydratase activity
F9277_RS01900	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
F9277_RS01930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F9277_RS01940	COG1546	Belongs to the CinA family
F9277_RS01945	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F9277_RS01960	COG0527	aspartate kinase activity
F9277_RS02015	COG3630	sodium ion export across plasma membrane
F9277_RS02020	COG0511	ligase activity, forming carbon-carbon bonds
F9277_RS02020	COG5016	pyruvate
F9277_RS02025	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
F9277_RS02035	COG1238	metal cluster binding
F9277_RS02040	COG0612	Peptidase, M16
F9277_RS02060	COG4536	flavin adenine dinucleotide binding
F9277_RS02065	COG4137	Cytochrome C assembly protein
F9277_RS02070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F9277_RS02095	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F9277_RS02100	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
F9277_RS02105	COG0237	dephospho-CoA kinase activity
F9277_RS02115	COG1459	type II secretion system
F9277_RS02120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F9277_RS02145	COG2186	Transcriptional regulator
F9277_RS02150	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F9277_RS02155	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9277_RS02160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9277_RS02175	COG0288	reversible hydration of carbon dioxide
F9277_RS02180	COG0659	secondary active sulfate transmembrane transporter activity
F9277_RS02185	COG1131	(ABC) transporter
F9277_RS02190	COG0842	Transport permease protein
F9277_RS02195	COG1560	Kdo2-lipid A biosynthetic process
F9277_RS02210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F9277_RS02225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9277_RS02240	COG1643	Atp-dependent helicase
F9277_RS02245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F9277_RS02250	COG1752	Esterase of the alpha-beta hydrolase superfamily
F9277_RS02255	COG1049	propionate catabolic process, 2-methylcitrate cycle
F9277_RS02270	COG0004	ammonium transporteR
F9277_RS02275	COG1840	ABC-type Fe3 transport system, periplasmic component
F9277_RS02285	COG3842	ATPase activity
F9277_RS02290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F9277_RS02305	COG2971	BadF BadG BcrA BcrD
F9277_RS02315	COG4608	Belongs to the ABC transporter superfamily
F9277_RS02320	COG0444	Belongs to the ABC transporter superfamily
F9277_RS02325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F9277_RS02335	COG0747	negative chemotaxis
F9277_RS02340	COG2198	Histidine kinase
F9277_RS02340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9277_RS02340	COG2205	protein histidine kinase activity
F9277_RS02340	COG0784	Response regulator, receiver
F9277_RS02355	COG0628	permease
F9277_RS02365	COG0316	Belongs to the HesB IscA family
F9277_RS02380	COG0739	heme binding
F9277_RS02385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F9277_RS02395	COG2027	D-alanyl-D-alanine carboxypeptidase
F9277_RS02400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F9277_RS02405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F9277_RS02410	COG1534	Rna-binding protein
F9277_RS02420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F9277_RS02425	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F9277_RS02435	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F9277_RS02455	COG0195	Participates in both transcription termination and antitermination
F9277_RS02475	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
F9277_RS02495	COG0534	Mate efflux family protein
F9277_RS02500	COG0826	peptidase U32
F9277_RS02505	COG0826	peptidase U32
F9277_RS02515	COG3154	lipid carrier protein
F9277_RS02520	COG3153	acetyltransferase
F9277_RS02540	COG3706	GGDEF domain
F9277_RS02545	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F9277_RS02550	COG0084	hydrolase, TatD family'
F9277_RS02555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F9277_RS02565	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
F9277_RS02575	COG0813	purine-nucleoside phosphorylase activity
F9277_RS02585	COG0560	Phosphoserine phosphatase
F9277_RS02595	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
F9277_RS02600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F9277_RS02605	COG0583	DNA-binding transcription factor activity
F9277_RS02615	COG1022	Amp-dependent synthetase and ligase
F9277_RS02620	COG2169	Transcriptional regulator
F9277_RS02645	COG4964	Belongs to the GSP D family
F9277_RS02705	COG0583	DNA-binding transcription factor activity
F9277_RS02710	COG0531	amino acid
F9277_RS02715	COG2731	YhcH YjgK YiaL family protein
F9277_RS02720	COG3250	beta-galactosidase activity
F9277_RS02725	COG1609	Transcriptional regulator
F9277_RS02735	COG0768	penicillin binding
F9277_RS02740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F9277_RS02755	COG2017	converts alpha-aldose to the beta-anomer
F9277_RS02765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F9277_RS02765	COG1263	PTS System
F9277_RS02775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9277_RS02800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F9277_RS02805	COG1349	DNA-binding transcription factor activity
F9277_RS02815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F9277_RS02825	COG2271	Major facilitator Superfamily
F9277_RS02830	COG0584	glycerophosphoryl diester phosphodiesterase
F9277_RS02835	COG2171	N-acyltransferase activity
F9277_RS02850	COG3141	response to X-ray
F9277_RS02870	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F9277_RS02875	COG1074	ATP-dependent DNA helicase activity
F9277_RS02880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F9277_RS02905	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F9277_RS02905	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F9277_RS02920	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F9277_RS02925	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F9277_RS02930	COG2166	iron-sulfur cluster assembly
F9277_RS02935	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F9277_RS02940	COG0693	protein deglycase activity
F9277_RS02945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F9277_RS02950	COG3248	Nucleoside-binding outer membrane protein
F9277_RS02970	COG1595	DNA-templated transcription, initiation
F9277_RS03000	COG0271	Belongs to the BolA IbaG family
F9277_RS03025	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F9277_RS03035	COG1477	protein flavinylation
F9277_RS03050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F9277_RS03055	COG0514	ATP-dependent DNA helicase (RecQ)
F9277_RS03060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F9277_RS03075	COG0733	neurotransmitter:sodium symporter activity
F9277_RS03100	COG1720	tRNA m6t6A37 methyltransferase activity
F9277_RS03115	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
F9277_RS03140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F9277_RS03180	COG3098	single-species biofilm formation
F9277_RS03185	COG0564	pseudouridine synthase activity
F9277_RS03200	COG0024	Methionine aminopeptidase
F9277_RS03225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F9277_RS03230	COG0575	Belongs to the CDS family
F9277_RS03240	COG0750	zinc metalloprotease
F9277_RS03250	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
F9277_RS03255	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9277_RS03280	COG0587	DNA-directed DNA polymerase activity
F9277_RS03300	COG0347	Belongs to the P(II) protein family
F9277_RS03315	COG1388	LysM domain
F9277_RS03315	COG0741	lytic transglycosylase activity
F9277_RS03325	COG2226	methyltransferase
F9277_RS03335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F9277_RS03360	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
F9277_RS03365	COG0121	glutamine amidotransferase
F9277_RS03370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F9277_RS03380	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F9277_RS03385	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
F9277_RS03390	COG2233	PERMEase
F9277_RS03410	COG1393	Belongs to the ArsC family
F9277_RS03415	COG4783	chaperone-mediated protein folding
F9277_RS03430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F9277_RS03435	COG2716	regulation of RNA biosynthetic process
F9277_RS03440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9277_RS03445	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
F9277_RS03465	COG1393	Belongs to the ArsC family
F9277_RS03490	COG2837	iron assimilation
F9277_RS03495	COG2169	Transcriptional regulator
F9277_RS03500	COG1486	melibiose metabolic process
F9277_RS03505	COG2211	Major facilitator Superfamily
F9277_RS03510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F9277_RS03520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F9277_RS03530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F9277_RS03535	COG1334	flagellar protein FlaG
F9277_RS03540	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
F9277_RS03550	COG1516	flagellar protein fliS
F9277_RS03570	COG1677	Flagellar hook-basal body complex protein FliE
F9277_RS03580	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F9277_RS03635	COG1987	bacterial-type flagellum assembly
F9277_RS03640	COG1684	flagellar biosynthetic protein fliR
F9277_RS03675	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
F9277_RS03680	COG2198	Histidine kinase
F9277_RS03680	COG0784	Response regulator, receiver
F9277_RS03680	COG0643	Histidine kinase
F9277_RS03685	COG2201	protein-glutamate methylesterase activity
F9277_RS03690	COG1192	Involved in chromosome partitioning
F9277_RS03700	COG0835	chemotaxis
F9277_RS03710	COG4133	protoheme IX ABC transporter activity
F9277_RS03715	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F9277_RS03720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F9277_RS03735	COG1138	Cytochrome C-type biogenesis protein
F9277_RS03740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F9277_RS03750	COG3088	subunit of a heme lyase
F9277_RS03750	COG4235	cytochrome complex assembly
F9277_RS03755	COG2853	Lipoprotein
F9277_RS03780	COG0183	Belongs to the thiolase family
F9277_RS03800	COG2062	phosphohistidine phosphatase, SixA
F9277_RS03810	COG2890	protein-(glutamine-N5) methyltransferase activity
F9277_RS03820	COG2860	membrane
F9277_RS03825	COG3101	peptidyl-lysine hydroxylation
F9277_RS03845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F9277_RS03855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F9277_RS03860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F9277_RS03885	COG0285	dihydrofolate synthase activity
F9277_RS03890	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
F9277_RS03895	COG1286	toxin biosynthetic process
F9277_RS03900	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F9277_RS03905	COG0583	DNA-binding transcription factor activity
F9277_RS03910	COG0745	RESPONSE REGULATOR receiver
F9277_RS03920	COG2832	Protein of unknown function (DUF454)
F9277_RS03930	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F9277_RS03940	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F9277_RS03945	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F9277_RS03950	COG0814	amino acid
F9277_RS03955	COG0251	oxidation-reduction process
F9277_RS03965	COG2964	Protein conserved in bacteria
F9277_RS03975	COG2983	Belongs to the UPF0260 family
F9277_RS03980	COG2261	transglycosylase associated protein
F9277_RS03985	COG0668	transmembrane transport
F9277_RS03990	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F9277_RS03995	COG0346	lactoylglutathione lyase activity
F9277_RS04005	COG1785	Belongs to the alkaline phosphatase family
F9277_RS04025	COG2226	methyltransferase
F9277_RS04045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F9277_RS04050	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F9277_RS04060	COG3139	Protein of unknown function (DUF1315)
F9277_RS04065	COG0252	asparaginase activity
F9277_RS04070	COG0616	signal peptide processing
F9277_RS04075	COG1902	pentaerythritol trinitrate reductase activity
F9277_RS04075	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9277_RS04080	COG0778	Nitroreductase
F9277_RS04085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F9277_RS04100	COG0123	including yeast histone deacetylase and acetoin utilization protein
F9277_RS04110	COG3083	sulfuric ester hydrolase activity
F9277_RS04135	COG1757	Na H antiporter
F9277_RS04140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F9277_RS04145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F9277_RS04150	COG2095	MarC family integral membrane protein
F9277_RS04155	COG1012	belongs to the aldehyde dehydrogenase family
F9277_RS04155	COG1454	alcohol dehydrogenase
F9277_RS04175	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F9277_RS04185	COG2056	Na+-H+ antiporter family
F9277_RS04195	COG2885	chlorophyll binding
F9277_RS04205	COG0346	lactoylglutathione lyase activity
F9277_RS04210	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F9277_RS04215	COG4660	Part of a membrane complex involved in electron transport
F9277_RS04220	COG4659	FMN binding
F9277_RS04225	COG4658	electron transport chain
F9277_RS04230	COG4656	Part of a membrane complex involved in electron transport
F9277_RS04240	COG4657	Part of a membrane complex involved in electron transport
F9277_RS04245	COG1882	Formate acetyltransferase
F9277_RS04255	COG0556	nucleotide-excision repair
F9277_RS04270	COG0391	Required for morphogenesis under gluconeogenic growth conditions
F9277_RS04275	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F9277_RS04280	COG0521	Mo-molybdopterin cofactor biosynthetic process
F9277_RS04290	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
F9277_RS04295	COG0314	molybdopterin synthase activity
F9277_RS04305	COG0601	transmembrane transport
F9277_RS04310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F9277_RS04315	COG0444	Belongs to the ABC transporter superfamily
F9277_RS04325	COG0435	Glutathione S-transferase
F9277_RS04330	COG3174	membrane
F9277_RS04335	COG0857	belongs to the CobB CobQ family
F9277_RS04335	COG0280	phosphate acetyltransferase
F9277_RS04360	COG4120	Belongs to the binding-protein-dependent transport system permease family
F9277_RS04365	COG1122	ATPase activity
F9277_RS04370	COG0366	Alpha amylase catalytic
F9277_RS04375	COG3706	GGDEF domain
F9277_RS04380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F9277_RS04385	COG0653	protein targeting
F9277_RS04390	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F9277_RS04400	COG2186	Transcriptional regulator
F9277_RS04430	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
F9277_RS04435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F9277_RS04440	COG0659	secondary active sulfate transmembrane transporter activity
F9277_RS04450	COG1530	ribonuclease E activity
F9277_RS04455	COG0564	pseudouridine synthase activity
F9277_RS04460	COG0424	maF-like protein
F9277_RS04465	COG1399	metal-binding, possibly nucleic acid-binding protein
F9277_RS04480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F9277_RS04510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F9277_RS04525	COG0084	hydrolase, TatD family'
F9277_RS04530	COG1263	PTS System
F9277_RS04530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F9277_RS04545	COG0733	neurotransmitter:sodium symporter activity
F9277_RS04560	COG4667	esterase of the alpha-beta hydrolase superfamily
F9277_RS04570	COG1940	carbohydrate kinase activity
F9277_RS04575	COG0784	Response regulator, receiver
F9277_RS04575	COG0835	chemotaxis
F9277_RS04595	COG1028	Short-chain dehydrogenase reductase Sdr
F9277_RS04600	COG0616	signal peptide processing
F9277_RS04610	COG0539	negative regulation of cytoplasmic translation
F9277_RS04620	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
F9277_RS04625	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
F9277_RS04635	COG4166	transmembrane transport
F9277_RS04690	COG3009	Protein conserved in bacteria
F9277_RS04695	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F9277_RS04695	COG3008	intermembrane lipid transfer
F9277_RS04700	COG2995	paraquat-inducible protein a
F9277_RS04715	COG4232	protein-disulfide reductase activity
F9277_RS04720	COG3118	belongs to the thioredoxin family
F9277_RS04730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F9277_RS04760	COG3153	acetyltransferase
F9277_RS04785	COG0577	efflux transmembrane transporter activity
F9277_RS04795	COG1136	(ABC) transporter
F9277_RS04795	COG0577	efflux transmembrane transporter activity
F9277_RS04840	COG1846	Transcriptional regulator
F9277_RS04875	COG3850	Histidine kinase
F9277_RS04875	COG5002	protein histidine kinase activity
F9277_RS04880	COG0745	RESPONSE REGULATOR receiver
F9277_RS04885	COG0463	Glycosyl transferase, family 2
F9277_RS04890	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F9277_RS04900	COG0840	transmembrane signaling receptor activity
F9277_RS04905	COG2964	Protein conserved in bacteria
F9277_RS04920	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9277_RS04945	COG1032	radical SAM domain protein
F9277_RS04950	COG5001	Diguanylate cyclase
F9277_RS04950	COG1716	ATPase activity
F9277_RS04980	COG2350	Protein conserved in bacteria
F9277_RS04985	COG1607	acyl-coa hydrolase
F9277_RS05010	COG1301	dicarboxylic acid transport
F9277_RS05015	COG0159	tryptophan synthase activity
F9277_RS05025	COG0135	phosphoribosylanthranilate isomerase activity
F9277_RS05025	COG0134	indole-3-glycerol-phosphate synthase activity
F9277_RS05035	COG0512	Glutamine amidotransferase of anthranilate synthase
F9277_RS05040	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F9277_RS05050	COG0613	PHP domain protein
F9277_RS05055	COG0009	L-threonylcarbamoyladenylate synthase
F9277_RS05065	COG1187	pseudouridine synthase activity
F9277_RS05165	COG0758	DNA mediated transformation
F9277_RS05175	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F9277_RS05180	COG0417	DNA replication proofreading
F9277_RS05185	COG2197	response regulator
F9277_RS05190	COG0322	excinuclease ABC activity
F9277_RS05235	COG0019	diaminopimelate decarboxylase activity
F9277_RS05260	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F9277_RS05265	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F9277_RS05275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F9277_RS05295	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
F9277_RS05305	COG0437	4 iron, 4 sulfur cluster binding
F9277_RS05310	COG3301	Polysulphide reductase, NrfD
F9277_RS05315	COG1138	Cytochrome C-type biogenesis protein
F9277_RS05325	COG4235	cytochrome complex assembly
F9277_RS05325	COG3088	subunit of a heme lyase
F9277_RS05335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F9277_RS05360	COG2989	Protein conserved in bacteria
F9277_RS05365	COG3108	Peptidase M15
F9277_RS05370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9277_RS05385	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F9277_RS05410	COG1846	Transcriptional regulator
F9277_RS05415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9277_RS05420	COG0840	transmembrane signaling receptor activity
F9277_RS05440	COG1448	Aminotransferase
F9277_RS05445	COG3437	response regulator, receiver
F9277_RS05445	COG2770	Histidine kinase
F9277_RS05460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9277_RS05475	COG0017	Asparaginyl-tRNA synthetase
F9277_RS05480	COG0840	transmembrane signaling receptor activity
F9277_RS05485	COG0720	synthase
F9277_RS05490	COG2197	response regulator
F9277_RS05500	COG5001	Diguanylate cyclase
F9277_RS05500	COG3300	MHYT domain
F9277_RS05505	COG1760	l-serine dehydratase
F9277_RS05510	COG0814	amino acid
F9277_RS05525	COG0784	Response regulator, receiver
F9277_RS05525	COG2205	protein histidine kinase activity
F9277_RS05530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F9277_RS05545	COG3106	COG3106 Predicted ATPase
F9277_RS05560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F9277_RS05600	COG3196	Protein conserved in bacteria
F9277_RS05765	COG0791	NLP P60 protein
F9277_RS05870	COG0494	nUDIX hydrolase
F9277_RS05880	COG0625	glutathione transferase activity
F9277_RS05920	COG0519	Catalyzes the synthesis of GMP from XMP
F9277_RS06435	COG3196	Protein conserved in bacteria
F9277_RS06620	COG3340	Belongs to the peptidase S51 family
F9277_RS06690	COG2026	Addiction module toxin, RelE StbE family
F9277_RS06845	COG0519	Catalyzes the synthesis of GMP from XMP
F9277_RS06890	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F9277_RS06925	COG0277	FAD linked oxidase domain protein
F9277_RS06925	COG0247	lactate metabolic process
F9277_RS06940	COG2986	histidine ammonia-lyase
F9277_RS06950	COG0010	Belongs to the arginase family
F9277_RS06960	COG2188	Transcriptional regulator
F9277_RS06985	COG0291	Belongs to the bacterial ribosomal protein bL35 family
F9277_RS06995	COG0251	oxidation-reduction process
F9277_RS07050	COG0072	phenylalanine-tRNA ligase activity
F9277_RS07050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9277_RS07115	COG1346	cytolysis
F9277_RS07125	COG2925	Exonuclease
F9277_RS07135	COG1823	symporter activity
F9277_RS07140	COG0702	epimerase
F9277_RS07145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9277_RS07155	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
F9277_RS07165	COG2062	phosphohistidine phosphatase, SixA
F9277_RS07180	COG4139	cobalamin transport
F9277_RS07240	COG0583	DNA-binding transcription factor activity
F9277_RS07265	COG2165	general secretion pathway protein
F9277_RS07270	COG1451	nucleotide metabolic process
F9277_RS07300	COG3938	Belongs to the proline racemase family
F9277_RS07305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F9277_RS07315	COG2423	ornithine cyclodeaminase activity
F9277_RS07320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9277_RS07325	COG3842	ATPase activity
F9277_RS07330	COG1176	ABC-type spermidine putrescine transport system, permease component I
F9277_RS07335	COG1177	transmembrane transport
F9277_RS07345	COG0813	purine-nucleoside phosphorylase activity
F9277_RS07365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9277_RS07370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9277_RS07380	COG0745	RESPONSE REGULATOR receiver
F9277_RS07400	COG3291	Pkd domain containing protein
F9277_RS07420	COG0444	Belongs to the ABC transporter superfamily
F9277_RS07425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F9277_RS07430	COG0601	transmembrane transport
F9277_RS07440	COG2195	Cleaves the N-terminal amino acid of tripeptides
F9277_RS07455	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
F9277_RS07465	COG0625	glutathione transferase activity
F9277_RS07555	COG1051	belongs to the nudix hydrolase family
F9277_RS07600	COG4565	transcriptional regulatory protein
F9277_RS07610	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
F9277_RS07615	COG5016	pyruvate
F9277_RS07615	COG0511	ligase activity, forming carbon-carbon bonds
F9277_RS07620	COG3630	sodium ion export across plasma membrane
F9277_RS07630	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
F9277_RS07640	COG2301	Belongs to the HpcH HpaI aldolase family
F9277_RS07645	COG3051	citrate lyase alpha subunit
F9277_RS07655	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
F9277_RS07685	COG3284	Transcriptional regulator
F9277_RS07690	COG1012	belongs to the aldehyde dehydrogenase family
F9277_RS07695	COG1115	amino acid carrier protein
F9277_RS07730	COG1368	sulfuric ester hydrolase activity
F9277_RS07735	COG0215	cysteine-tRNA ligase activity
F9277_RS07740	COG0534	Mate efflux family protein
F9277_RS07745	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
F9277_RS07755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9277_RS07760	COG0456	acetyltransferase
F9277_RS07765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F9277_RS07770	COG0662	Cupin 2, conserved barrel domain protein
F9277_RS07775	COG0527	aspartate kinase activity
F9277_RS07790	COG1858	cytochrome C peroxidase
F9277_RS07795	COG1404	Belongs to the peptidase S8 family
F9277_RS07800	COG0583	DNA-binding transcription factor activity
F9277_RS07805	COG0702	epimerase
F9277_RS07820	COG2186	Transcriptional regulator
F9277_RS07860	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F9277_RS07865	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
F9277_RS07875	COG2814	Major facilitator Superfamily
F9277_RS07880	COG0583	DNA-binding transcription factor activity
F9277_RS07885	COG0515	serine threonine protein kinase
F9277_RS07885	COG4991	sh3 domain protein
F9277_RS07885	COG3064	Membrane
F9277_RS07905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9277_RS07920	COG3290	protein histidine kinase activity
F9277_RS07925	COG4565	transcriptional regulatory protein
F9277_RS07930	COG4774	siderophore transport
F9277_RS07940	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F9277_RS07945	COG0363	glucosamine-6-phosphate deaminase activity
F9277_RS07950	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F9277_RS07955	COG0589	response to stress
F9277_RS07975	COG2207	Transcriptional regulator
F9277_RS08000	COG4964	Belongs to the GSP D family
F9277_RS08060	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
F9277_RS08070	COG0668	transmembrane transport
F9277_RS08075	COG3247	response to pH
F9277_RS08085	COG1846	Transcriptional regulator
F9277_RS08110	COG0110	maltose O-acetyltransferase activity
F9277_RS08125	COG2205	protein histidine kinase activity
F9277_RS08125	COG4999	Histidine kinase
F9277_RS08125	COG3850	Histidine kinase
F9277_RS08125	COG3437	response regulator, receiver
F9277_RS08130	COG5001	Diguanylate cyclase
F9277_RS08130	COG3300	MHYT domain
F9277_RS08155	COG0840	transmembrane signaling receptor activity
F9277_RS08160	COG1254	Belongs to the acylphosphatase family
F9277_RS08165	COG2920	part of a sulfur-relay system
F9277_RS08170	COG0670	Belongs to the BI1 family
F9277_RS08175	COG1126	abc transporter atp-binding protein
F9277_RS08180	COG0765	amino acid transport
F9277_RS08185	COG4597	amino acid ABC transporter
F9277_RS08190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9277_RS08210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F9277_RS08235	COG3008	intermembrane lipid transfer
F9277_RS08240	COG2995	paraquat-inducible protein a
F9277_RS08245	COG1132	(ABC) transporter
F9277_RS08250	COG1956	GAF domain-containing protein
F9277_RS08255	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
F9277_RS08270	COG0308	aminopeptidase N
F9277_RS08280	COG2902	Dehydrogenase
F9277_RS08310	COG0488	(ABC) transporter
F9277_RS08325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F9277_RS08330	COG1067	ATP-dependent peptidase activity
F9277_RS08360	COG2205	protein histidine kinase activity
F9277_RS08360	COG0784	Response regulator, receiver
F9277_RS08375	COG3278	Belongs to the heme-copper respiratory oxidase family
F9277_RS08390	COG2010	Cytochrome c
F9277_RS08400	COG2217	Heavy metal translocating P-type atpase
F9277_RS08415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F9277_RS08420	COG0589	response to stress
F9277_RS08435	COG2992	FlgJ-related protein
F9277_RS08445	COG3842	ATPase activity
F9277_RS08455	COG1177	transmembrane transport
F9277_RS08465	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F9277_RS08470	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F9277_RS08490	COG0437	4 iron, 4 sulfur cluster binding
F9277_RS08495	COG0243	molybdopterin cofactor binding
F9277_RS08495	COG3383	formate dehydrogenase (NAD+) activity
F9277_RS08505	COG3381	protein complex oligomerization
F9277_RS08525	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F9277_RS08530	COG0488	(ABC) transporter
F9277_RS08550	COG4191	Histidine kinase
F9277_RS08555	COG2204	response regulator
F9277_RS08565	COG4662	Binding-protein-dependent transport system inner membrane component
F9277_RS08570	COG3842	ATPase activity
F9277_RS08580	COG0303	'Molybdopterin
F9277_RS08590	COG1940	carbohydrate kinase activity
F9277_RS08595	COG3148	PFAM DTW domain containing protein
F9277_RS08640	COG0840	transmembrane signaling receptor activity
F9277_RS08645	COG0791	NLP P60 protein
F9277_RS08710	COG4790	Type iii secretion
F9277_RS08725	COG3710	Transcriptional regulator
F9277_RS08755	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F9277_RS08830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F9277_RS08835	COG1518	maintenance of DNA repeat elements
F9277_RS08865	COG1203	CRISPR-associated helicase, Cas3
F9277_RS08905	COG3069	C4-dicarboxylate transmembrane transporter activity
F9277_RS08910	COG2195	Cleaves the N-terminal amino acid of tripeptides
F9277_RS08935	COG5492	domain, Protein
F9277_RS08935	COG4932	domain protein
F9277_RS08955	COG2003	Belongs to the UPF0758 family
F9277_RS08995	COG2188	Transcriptional regulator
F9277_RS09025	COG0714	Associated with various cellular activities
F9277_RS09030	COG0641	radical SAM
F9277_RS09035	COG3119	arylsulfatase activity
F9277_RS09045	COG1063	alcohol dehydrogenase
F9277_RS09050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F9277_RS09065	COG1454	alcohol dehydrogenase
F9277_RS09070	COG2801	Transposase and inactivated derivatives
F9277_RS09120	COG0840	transmembrane signaling receptor activity
F9277_RS09135	COG0840	transmembrane signaling receptor activity
F9277_RS09155	COG2003	Belongs to the UPF0758 family
F9277_RS09185	COG3706	GGDEF domain
F9277_RS09190	COG2201	protein-glutamate methylesterase activity
F9277_RS09195	COG3001	Fructosamine kinase
F9277_RS09205	COG0307	riboflavin synthase, alpha
F9277_RS09210	COG0534	Mate efflux family protein
F9277_RS09220	COG1793	dna ligase
F9277_RS09250	COG2204	response regulator
F9277_RS09290	COG0297	glycogen (starch) synthase activity
F9277_RS09300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F9277_RS09310	COG3064	Membrane
F9277_RS09340	COG2199	diguanylate cyclase activity
F9277_RS09340	COG2203	Gaf domain
F9277_RS09350	COG0602	queuosine metabolic process
F9277_RS09355	COG0561	phosphatase activity
F9277_RS09380	COG2828	Protein conserved in bacteria
F9277_RS09390	COG0372	Belongs to the citrate synthase family
F9277_RS09395	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
F9277_RS09505	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
F9277_RS09515	COG0456	acetyltransferase
F9277_RS09540	COG0730	response to heat
F9277_RS09545	COG2358	TRAP transporter, solute receptor (TAXI family
F9277_RS09550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9277_RS09565	COG1280	lysine exporter protein (LysE YggA)
F9277_RS09600	COG2197	response regulator
F9277_RS09605	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
F9277_RS09615	COG1846	Transcriptional regulator
F9277_RS09630	COG1560	Kdo2-lipid A biosynthetic process
F9277_RS09635	COG0583	DNA-binding transcription factor activity
F9277_RS09640	COG1280	lysine exporter protein (LysE YggA)
F9277_RS09645	COG0531	amino acid
F9277_RS09670	COG3063	Type IV pilus biogenesis stability protein PilW
F9277_RS09695	COG1643	Atp-dependent helicase
F9277_RS09700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F9277_RS09715	COG3302	dmso reductase anchor subunit
F9277_RS09720	COG0437	4 iron, 4 sulfur cluster binding
F9277_RS09725	COG0243	molybdopterin cofactor binding
F9277_RS09755	COG3706	GGDEF domain
F9277_RS09765	COG0443	Heat shock 70 kDa protein
F9277_RS09770	COG0443	Heat shock 70 kDa protein
F9277_RS09795	COG0583	DNA-binding transcription factor activity
F9277_RS09805	COG2165	general secretion pathway protein
F9277_RS09810	COG1132	(ABC) transporter
F9277_RS09815	COG1132	(ABC) transporter
F9277_RS09830	COG4774	siderophore transport
F9277_RS09835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F9277_RS09840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F9277_RS09845	COG1120	ATPase activity
F9277_RS09860	COG0814	amino acid
F9277_RS09865	COG1454	alcohol dehydrogenase
F9277_RS09875	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
F9277_RS09885	COG0861	Integral membrane protein TerC family
F9277_RS09895	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F9277_RS09900	COG1328	CTP reductase activity
F9277_RS09905	COG1280	lysine exporter protein (LysE YggA)
F9277_RS09915	COG5001	Diguanylate cyclase
F9277_RS09915	COG3300	MHYT domain
F9277_RS09925	COG4191	Histidine kinase
F9277_RS09925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9277_RS09930	COG0471	metal ion transport
F9277_RS09975	COG1643	Atp-dependent helicase
F9277_RS09985	COG2949	membrane
F9277_RS09990	COG0471	metal ion transport
F9277_RS09995	COG3706	GGDEF domain
F9277_RS10015	COG0492	ferredoxin-NADP+ reductase activity
F9277_RS10020	COG4988	ABC transporter
F9277_RS10025	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F9277_RS10035	COG2610	gluconate transmembrane transporter activity
F9277_RS10040	COG0583	DNA-binding transcription factor activity
F9277_RS10060	COG3706	GGDEF domain
F9277_RS10070	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
F9277_RS10080	COG4191	Histidine kinase
F9277_RS10080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9277_RS10095	COG3070	regulator of competence-specific genes
F9277_RS10110	COG2431	L-lysine efflux transmembrane transporter activity
F9277_RS10120	COG0076	glutamate decarboxylase activity
F9277_RS10125	COG1737	Transcriptional regulator
F9277_RS10135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F9277_RS10145	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F9277_RS10175	COG4181	ATPase activity
F9277_RS10180	COG0534	Mate efflux family protein
F9277_RS10185	COG0702	epimerase
F9277_RS10190	COG1609	Transcriptional regulator
F9277_RS10200	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9277_RS10210	COG2814	Major facilitator Superfamily
F9277_RS10215	COG1187	pseudouridine synthase activity
F9277_RS10220	COG1061	Type III restriction enzyme res subunit
F9277_RS10275	COG3313	Fe-S protein
F9277_RS10285	COG0659	secondary active sulfate transmembrane transporter activity
F9277_RS10310	COG0493	'glutamate synthase
F9277_RS10320	COG0398	Pfam SNARE associated Golgi protein
F9277_RS10325	COG4134	Bacterial extracellular solute-binding protein
F9277_RS10330	COG4135	transport system, permease component
F9277_RS10335	COG4136	ATPase activity
F9277_RS10340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F9277_RS10345	COG3604	Transcriptional regulator
F9277_RS10350	COG1151	hydroxylamine reductase activity
F9277_RS10355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F9277_RS10365	COG0564	pseudouridine synthase activity
F9277_RS10375	COG0733	neurotransmitter:sodium symporter activity
F9277_RS10385	COG0626	cystathionine gamma-synthase activity
F9277_RS10390	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
F9277_RS10395	COG5380	lipid catabolic process
F9277_RS10400	COG2818	Glycosylase
F9277_RS10430	COG1842	Phage shock protein A
F9277_RS10435	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F9277_RS10450	COG4171	peptide transport system, permease
F9277_RS10460	COG4172	Belongs to the ABC transporter superfamily
F9277_RS10470	COG1227	inorganic diphosphatase activity
F9277_RS10475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F9277_RS10480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F9277_RS10485	COG1121	(ABC) transporter
F9277_RS10500	COG0243	molybdopterin cofactor binding
F9277_RS10505	COG3005	denitrification pathway
F9277_RS10510	COG4459	periplasmic nitrate reductase
F9277_RS10515	COG0390	transport system, permease component
F9277_RS10520	COG2116	formate transmembrane transporter activity
F9277_RS10545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F9277_RS10550	COG1435	thymidine kinase activity
F9277_RS10555	COG0215	cysteine-tRNA ligase activity
F9277_RS10560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F9277_RS10565	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9277_RS10570	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
F9277_RS10575	COG3012	SEC-C Motif Domain Protein
F9277_RS10580	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F9277_RS10580	COG0140	phosphoribosyl-ATP diphosphatase activity
F9277_RS10590	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
F9277_RS10595	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F9277_RS10600	COG0131	Imidazoleglycerol-phosphate dehydratase
F9277_RS10600	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F9277_RS10605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F9277_RS10610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F9277_RS10625	COG1757	Na H antiporter
F9277_RS10635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9277_RS10645	COG0482	sulfurtransferase activity
F9277_RS10655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F9277_RS10665	COG2268	Band 7 protein
F9277_RS10675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F9277_RS10690	COG0300	oxidoreductase activity
F9277_RS10735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F9277_RS10755	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F9277_RS10765	COG1674	ftsk spoiiie
F9277_RS10775	COG0686	Belongs to the AlaDH PNT family
F9277_RS10810	COG4934	collagen metabolic process
F9277_RS10820	COG3568	Endonuclease Exonuclease Phosphatase
F9277_RS10845	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F9277_RS10860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9277_RS10865	COG0800	Aldolase
F9277_RS10870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9277_RS10875	COG1917	Cupin 2, conserved barrel domain protein
F9277_RS10895	COG2186	Transcriptional regulator
F9277_RS10900	COG1028	Short-chain dehydrogenase reductase Sdr
F9277_RS10905	COG2186	Transcriptional regulator
F9277_RS10910	COG0517	IMP dehydrogenase activity
F9277_RS10915	COG2176	DNA-directed DNA polymerase activity
F9277_RS10935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9277_RS10960	COG1288	antiporter activity
F9277_RS10970	COG2186	Transcriptional regulator
F9277_RS10980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9277_RS10985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9277_RS11020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F9277_RS11035	COG2824	Alkylphosphonate utilization operon protein PhnA
F9277_RS11040	COG1621	beta-fructofuranosidase activity
F9277_RS11045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9277_RS11050	COG1263	PTS System
F9277_RS11050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F9277_RS11065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F9277_RS11070	COG0789	Transcriptional regulator
F9277_RS11085	COG0457	Tetratricopeptide repeat
F9277_RS11155	COG4790	Type iii secretion
F9277_RS11160	COG4794	Type iii secretion
F9277_RS11165	COG4791	protein targeting
F9277_RS11170	COG4792	protein secretion
F9277_RS11215	COG4669	(LipO)protein
F9277_RS11295	COG5002	protein histidine kinase activity
F9277_RS11295	COG0784	Response regulator, receiver
F9277_RS11305	COG0754	glutathionylspermidine amidase activity
F9277_RS11315	COG3766	membrane
F9277_RS11335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F9277_RS11340	COG0371	Dehydrogenase
F9277_RS11345	COG2207	Transcriptional regulator
F9277_RS11350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9277_RS11355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F9277_RS11360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F9277_RS11365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F9277_RS11370	COG1882	Formate acetyltransferase
F9277_RS11375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9277_RS11380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9277_RS11385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9277_RS11385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F9277_RS11385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9277_RS11390	COG0673	inositol 2-dehydrogenase activity
F9277_RS11405	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
F9277_RS11410	COG2885	chlorophyll binding
F9277_RS11415	COG0823	Involved in the tonB-independent uptake of proteins
F9277_RS11430	COG0811	peptide transport
F9277_RS11435	COG0824	Thioesterase
F9277_RS11445	COG4890	Cyd operon protein YbgT
F9277_RS11450	COG1294	oxidase, subunit
F9277_RS11455	COG1271	oxidase subunit
F9277_RS11465	COG0632	four-way junction helicase activity
F9277_RS11470	COG0840	transmembrane signaling receptor activity
F9277_RS11485	COG1801	Protein of unknown function DUF72
F9277_RS11505	COG4067	protein conserved in archaea
F9277_RS11505	COG0189	ligase activity
F9277_RS11525	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
F9277_RS11530	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
F9277_RS11540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F9277_RS11545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F9277_RS11550	COG0745	RESPONSE REGULATOR receiver
F9277_RS11565	COG3070	regulator of competence-specific genes
F9277_RS11585	COG0297	glycogen (starch) synthase activity
F9277_RS11590	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
F9277_RS11595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F9277_RS11625	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F9277_RS11630	COG0542	response to heat
F9277_RS11640	COG1278	Cold shock
F9277_RS11650	COG1187	pseudouridine synthase activity
F9277_RS11655	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
F9277_RS11665	COG1199	ATP-dependent helicase activity
F9277_RS11670	COG0730	response to heat
F9277_RS11685	COG0840	transmembrane signaling receptor activity
F9277_RS11690	COG0708	Exodeoxyribonuclease III
F9277_RS11730	COG1882	Formate acetyltransferase
F9277_RS11740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F9277_RS11760	COG2766	serine protein kinase
F9277_RS11765	COG2718	Belongs to the UPF0229 family
F9277_RS11770	COG2719	SpoVR family
F9277_RS11790	COG1132	(ABC) transporter
F9277_RS11805	COG4591	ABC-type transport system involved in lipoprotein release permease component
F9277_RS11810	COG1136	(ABC) transporter
F9277_RS11815	COG4591	ABC-type transport system involved in lipoprotein release permease component
F9277_RS11825	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F9277_RS11840	COG1252	NADH dehydrogenase
F9277_RS11870	COG0537	adenosine 5'-monophosphoramidase activity
F9277_RS11890	COG2217	Heavy metal translocating P-type atpase
F9277_RS11900	COG0617	tRNA 3'-terminal CCA addition
F9277_RS11900	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
F9277_RS11900	COG0517	IMP dehydrogenase activity
F9277_RS11905	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
F9277_RS11910	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F9277_RS11915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9277_RS11920	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
F9277_RS11945	COG3126	Type III secretion system lipoprotein chaperone (YscW)
F9277_RS11950	COG1946	Acyl-CoA thioesterase
F9277_RS11960	COG1522	sequence-specific DNA binding
F9277_RS11985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9277_RS12035	COG0477	Major facilitator Superfamily
F9277_RS12040	COG2855	membrane
F9277_RS12055	COG0583	DNA-binding transcription factor activity
F9277_RS12060	COG2190	(PTS) system
F9277_RS12060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F9277_RS12060	COG1263	PTS System
F9277_RS12075	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
F9277_RS12080	COG0596	Alpha beta hydrolase
F9277_RS12090	COG1169	isochorismate synthase
F9277_RS12095	COG0436	Aminotransferase
F9277_RS12100	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
F9277_RS12125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9277_RS12130	COG0776	regulation of translation
F9277_RS12135	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F9277_RS12160	COG4191	Histidine kinase
F9277_RS12175	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F9277_RS12180	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F9277_RS12185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F9277_RS12200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F9277_RS12205	COG0569	domain protein
F9277_RS12210	COG0513	Belongs to the DEAD box helicase family
F9277_RS12215	COG1253	flavin adenine dinucleotide binding
F9277_RS12220	COG4771	TonB-dependent receptor
F9277_RS12235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F9277_RS12235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F9277_RS12240	COG1535	isochorismatase
F9277_RS12240	COG3433	isochorismatase activity
F9277_RS12245	COG1021	2,3-dihydroxybenzoate-AMP ligase
F9277_RS12250	COG1169	isochorismate synthase
F9277_RS12260	COG1028	Short-chain dehydrogenase reductase Sdr
F9277_RS12300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F9277_RS12305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F9277_RS12325	COG1216	Glycosyl transferase, family 2
F9277_RS12330	COG2986	histidine ammonia-lyase
F9277_RS12365	COG1028	Short-chain dehydrogenase reductase Sdr
F9277_RS12400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F9277_RS12410	COG2951	lytic endotransglycosylase activity
F9277_RS12425	COG2894	cell division
F9277_RS12430	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
F9277_RS12435	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F9277_RS12440	COG0318	PFAM AMP-dependent synthetase and ligase
F9277_RS12445	COG2267	carboxylic ester hydrolase activity
F9277_RS12450	COG3065	identical protein binding
F9277_RS12460	COG1214	PFAM Peptidase M22, glycoprotease
F9277_RS12465	COG1199	ATP-dependent helicase activity
F9277_RS12470	COG0788	formyltetrahydrofolate deformylase activity
F9277_RS12475	COG3102	Protein conserved in bacteria
F9277_RS12510	COG1918	ferrous iron import across plasma membrane
F9277_RS12515	COG4977	sequence-specific DNA binding
F9277_RS12520	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
F9277_RS12525	COG1121	(ABC) transporter
F9277_RS12530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F9277_RS12545	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9277_RS12550	COG0567	Dehydrogenase, E1 component
F9277_RS12560	COG1053	succinate dehydrogenase
F9277_RS12565	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F9277_RS12580	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F9277_RS12595	COG0033	Phosphoglucomutase
F9277_RS12600	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
F9277_RS12605	COG0596	Alpha beta hydrolase
F9277_RS12615	COG0716	FMN binding
F9277_RS12625	COG0735	belongs to the Fur family
F9277_RS12630	COG2165	general secretion pathway protein
F9277_RS12640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F9277_RS12640	COG1263	PTS System
F9277_RS12640	COG2190	(PTS) system
F9277_RS12650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F9277_RS12655	COG1846	Transcriptional regulator
F9277_RS12655	COG1940	carbohydrate kinase activity
F9277_RS12660	COG4651	solute:proton antiporter activity
F9277_RS12660	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F9277_RS12665	COG0367	asparagine synthase
F9277_RS12675	COG3104	oligopeptide transport
F9277_RS12680	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F9277_RS12695	COG3710	Transcriptional regulator
F9277_RS12715	COG0622	Phosphoesterase
F9277_RS12745	COG1090	epimerase
F9277_RS12750	COG0300	oxidoreductase activity
F9277_RS12760	COG3118	belongs to the thioredoxin family
F9277_RS12765	COG0330	HflC and HflK could
F9277_RS12800	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
F9277_RS12805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F9277_RS12815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9277_RS12820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F9277_RS12825	COG2190	(PTS) system
F9277_RS12830	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F9277_RS12835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F9277_RS12840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F9277_RS12855	COG1705	Flagellar rod assembly protein muramidase FlgJ
F9277_RS12855	COG3951	Flagellar rod assembly protein muramidase FlgJ
F9277_RS12860	COG1706	bacterial-type flagellum-dependent cell motility
F9277_RS12865	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
F9277_RS12875	COG4787	bacterial-type flagellum-dependent cell motility
F9277_RS12895	COG1558	bacterial-type flagellum-dependent cell motility
F9277_RS12900	COG1815	bacterial-type flagellum-dependent cell motility
F9277_RS12905	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F9277_RS12910	COG0835	chemotaxis
F9277_RS12910	COG0784	Response regulator, receiver
F9277_RS12965	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
F9277_RS12980	COG2608	mercury ion transmembrane transporter activity
F9277_RS12980	COG2217	Heavy metal translocating P-type atpase
F9277_RS13025	COG2840	Smr protein MutS2
F9277_RS13030	COG1187	pseudouridine synthase activity
F9277_RS13035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F9277_RS13040	COG0737	Belongs to the 5'-nucleotidase family
F9277_RS13045	COG2877	3-deoxy-8-phosphooctulonate synthase activity
F9277_RS13050	COG2912	Transglutaminase-like superfamily
F9277_RS13055	COG3094	Invasion gene expression up-regulator, SirB
F9277_RS13060	COG2890	protein-(glutamine-N5) methyltransferase activity
F9277_RS13085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F9277_RS13210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9277_RS13225	COG1702	phosphate starvation-inducible protein PhoH
F9277_RS13235	COG4535	Mg2 and Co2 transporter CorC
F9277_RS13240	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F9277_RS13245	COG2888	peptidyl-tyrosine sulfation
F9277_RS13255	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
F9277_RS13260	COG1466	dna polymerase III delta subunit
F9277_RS13265	COG0799	negative regulation of ribosome biogenesis
F9277_RS13275	COG0768	penicillin binding
F9277_RS13280	COG0772	Belongs to the SEDS family
F9277_RS13285	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F9277_RS13290	COG1686	Belongs to the peptidase S11 family
F9277_RS13310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F9277_RS13315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F9277_RS13330	COG0366	Alpha amylase catalytic
F9277_RS13335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F9277_RS13335	COG1263	PTS System
F9277_RS13345	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F9277_RS13350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F9277_RS13355	COG2011	ABC-type metal ion transport system permease component
F9277_RS13360	COG1464	Belongs to the NlpA lipoprotein family
F9277_RS13370	COG0737	Belongs to the 5'-nucleotidase family
F9277_RS13375	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
F9277_RS13400	COG1611	Belongs to the LOG family
F9277_RS13420	COG2363	Small membrane protein
F9277_RS13430	COG0583	DNA-binding transcription factor activity
F9277_RS13445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F9277_RS13455	COG0142	geranyltranstransferase activity
F9277_RS13465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F9277_RS13470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F9277_RS13495	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F9277_RS13495	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F9277_RS13500	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F9277_RS13505	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
F9277_RS13520	COG1073	alpha beta
F9277_RS13525	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
F9277_RS13530	COG2252	PERMEase
F9277_RS13535	COG2195	Cleaves the N-terminal amino acid of tripeptides
F9277_RS13565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F9277_RS13565	COG0047	phosphoribosylformylglycinamidine synthase activity
F9277_RS13585	COG0590	tRNA wobble adenosine to inosine editing
F9277_RS13590	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
F9277_RS13610	COG4969	Belongs to the N-Me-Phe pilin family
F9277_RS13635	COG1301	dicarboxylic acid transport
F9277_RS13655	COG0497	DNA recombination
F9277_RS13660	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9277_RS13665	COG2914	Belongs to the UPF0125 (RnfH) family
F9277_RS13670	COG2867	negative regulation of translational initiation
F9277_RS13685	COG0583	DNA-binding transcription factor activity
F9277_RS13690	COG1289	transmembrane transporter activity
F9277_RS13710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F9277_RS13730	COG0719	Fe-S assembly protein
F9277_RS13735	COG0396	ATPase activity
F9277_RS13740	COG0719	Fe-S assembly protein
F9277_RS13745	COG0316	Belongs to the HesB IscA family
F9277_RS13750	COG2873	o-acetylhomoserine
F9277_RS13765	COG0583	DNA-binding transcription factor activity
F9277_RS13775	COG1115	amino acid carrier protein
F9277_RS13780	COG1584	GPR1 FUN34 yaaH family protein
F9277_RS13790	COG1757	Na H antiporter
F9277_RS13800	COG0516	GMP reductase activity
F9277_RS13800	COG0517	IMP dehydrogenase activity
F9277_RS13815	COG2199	diguanylate cyclase activity
F9277_RS13815	COG2203	Gaf domain
F9277_RS13830	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9277_RS13835	COG2976	Protein conserved in bacteria
F9277_RS13870	COG2975	iron-sulfur cluster assembly
F9277_RS13875	COG0633	Ferredoxin
F9277_RS13890	COG0316	Belongs to the HesB IscA family
F9277_RS13895	COG0822	iron-sulfur transferase activity
F9277_RS13910	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
F9277_RS13915	COG0483	inositol monophosphate 1-phosphatase activity
F9277_RS13930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F9277_RS13935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F9277_RS13940	COG1862	Preprotein translocase
F9277_RS13965	COG0517	IMP dehydrogenase activity
F9277_RS13975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F9277_RS13980	COG0583	DNA-binding transcription factor activity
F9277_RS13985	COG0450	alkyl hydroperoxide reductase
F9277_RS14015	COG0704	Plays a role in the regulation of phosphate uptake
F9277_RS14020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F9277_RS14025	COG0581	inorganic phosphate transmembrane transporter activity
F9277_RS14030	COG0573	inorganic phosphate transmembrane transporter activity
F9277_RS14035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
F9277_RS14040	COG0248	Ppx GppA phosphatase
F9277_RS14050	COG5002	protein histidine kinase activity
F9277_RS14055	COG0745	RESPONSE REGULATOR receiver
F9277_RS14065	COG0826	peptidase U32
F9277_RS14070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F9277_RS14080	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
F9277_RS14135	COG0542	response to heat
F9277_RS14140	COG1496	oxidoreductase activity
F9277_RS14145	COG0564	pseudouridine synthase activity
F9277_RS14150	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9277_RS14155	COG0741	lytic transglycosylase activity
F9277_RS14160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F9277_RS14165	COG1605	Chorismate mutase
F9277_RS14165	COG0077	Prephenate dehydratase
F9277_RS14170	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
F9277_RS14185	COG0488	(ABC) transporter
F9277_RS14195	COG0739	heme binding
F9277_RS14200	COG1605	Chorismate mutase
F9277_RS14200	COG0287	Prephenate dehydrogenase
F9277_RS14205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F9277_RS14215	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F9277_RS14235	COG1966	Carbon starvation protein
F9277_RS14240	COG3275	phosphorelay sensor kinase activity
F9277_RS14245	COG3279	Response regulator of the LytR AlgR family
F9277_RS14250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
F9277_RS14255	COG1047	Peptidyl-prolyl cis-trans
F9277_RS14270	COG0196	riboflavin kinase activity
F9277_RS14275	COG0728	peptidoglycan biosynthetic process
F9277_RS14280	COG0268	Binds directly to 16S ribosomal RNA
F9277_RS14285	COG0640	Transcriptional regulator
F9277_RS14290	COG0583	DNA-binding transcription factor activity
F9277_RS14295	COG1283	sodium-dependent phosphate transmembrane transporter activity
F9277_RS14310	COG0730	response to heat
F9277_RS14315	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
F9277_RS14335	COG0667	Aldo Keto reductase
F9277_RS14360	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F9277_RS14365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F9277_RS14370	COG4974	Belongs to the 'phage' integrase family
F9277_RS14375	COG0716	FMN binding
F9277_RS14390	COG0513	Belongs to the DEAD box helicase family
F9277_RS14400	COG3022	response to hydroperoxide
F9277_RS14465	COG1403	HNH endonuclease
F9277_RS14505	COG1115	amino acid carrier protein
F9277_RS14540	COG0431	NADPH-dependent FMN reductase
F9277_RS14545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F9277_RS14550	COG0083	homoserine kinase activity
F9277_RS14565	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F9277_RS14580	COG0745	RESPONSE REGULATOR receiver
F9277_RS14590	COG2198	Histidine kinase
F9277_RS14590	COG5002	protein histidine kinase activity
F9277_RS14590	COG0784	Response regulator, receiver
F9277_RS14600	COG5001	Diguanylate cyclase
F9277_RS14600	COG4251	negative regulation of phosphorylation
F9277_RS14600	COG3706	GGDEF domain
F9277_RS14600	COG2203	Gaf domain
F9277_RS14605	COG1242	4 iron, 4 sulfur cluster binding
F9277_RS14610	COG0069	glutamate synthase activity
F9277_RS14610	COG0070	glutamate synthase
F9277_RS14610	COG0067	glutamate synthase
F9277_RS14620	COG0070	glutamate synthase
F9277_RS14620	COG0067	glutamate synthase
F9277_RS14620	COG0069	glutamate synthase activity
F9277_RS14625	COG0493	'glutamate synthase
F9277_RS14650	COG2860	membrane
F9277_RS14655	COG0583	DNA-binding transcription factor activity
F9277_RS14660	COG0730	response to heat
F9277_RS14675	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F9277_RS14680	COG0505	Belongs to the CarA family
F9277_RS14690	COG0494	nUDIX hydrolase
F9277_RS14705	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F9277_RS14710	COG0849	cell division
F9277_RS14715	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F9277_RS14730	COG0772	Belongs to the SEDS family
F9277_RS14745	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F9277_RS14750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F9277_RS14755	COG0768	penicillin binding
F9277_RS14760	COG3116	cell division
F9277_RS14780	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F9277_RS14795	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
F9277_RS14800	COG2823	Periplasmic or secreted lipoprotein
F9277_RS14805	COG2969	positive regulation of protein catabolic process
F9277_RS14810	COG0625	glutathione transferase activity
F9277_RS14815	COG2857	Cytochrome c1
F9277_RS14820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F9277_RS14825	COG0723	plastoquinol--plastocyanin reductase activity
F9277_RS14845	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F9277_RS14855	COG3105	Protein conserved in bacteria
F9277_RS14870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F9277_RS14875	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F9277_RS14885	COG3150	esterase
F9277_RS14895	COG3151	Protein conserved in bacteria
F9277_RS14900	COG0494	nUDIX hydrolase
F9277_RS14905	COG1538	Outer membrane efflux protein
F9277_RS14915	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F9277_RS14925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F9277_RS14930	COG3025	triphosphatase activity
F9277_RS14935	COG1392	Phosphate transport regulator
F9277_RS14940	COG0306	phosphate transporter
F9277_RS14945	COG4991	sh3 domain protein
F9277_RS14955	COG3409	Peptidoglycan-binding domain 1 protein
F9277_RS14955	COG3267	Type II secretory pathway component ExeA
F9277_RS14970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F9277_RS14975	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F9277_RS14985	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F9277_RS14990	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F9277_RS14995	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F9277_RS15000	COG1610	YqeY-like protein
F9277_RS15005	COG0358	DNA primase activity
F9277_RS15080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9277_RS15080	COG2213	PTS system mannitol-specific
F9277_RS15090	COG3722	fumarate hydratase activity
F9277_RS15095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F9277_RS15100	COG5002	protein histidine kinase activity
F9277_RS15120	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F9277_RS15125	COG1349	DNA-binding transcription factor activity
F9277_RS15135	COG0469	pyruvate kinase activity
F9277_RS15145	COG3706	GGDEF domain
F9277_RS15150	COG0440	acetolactate synthase activity
F9277_RS15155	COG0028	Belongs to the TPP enzyme family
F9277_RS15160	COG1022	Amp-dependent synthetase and ligase
F9277_RS15165	COG0583	DNA-binding transcription factor activity
F9277_RS15175	COG0671	phosphoesterase, PA-phosphatase related
F9277_RS15190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F9277_RS15195	COG0473	3-isopropylmalate dehydrogenase activity
F9277_RS15215	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
F9277_RS15220	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F9277_RS15225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9277_RS15230	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F9277_RS15235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F9277_RS15255	COG3610	response to peptide
F9277_RS15260	COG2966	Psort location CytoplasmicMembrane, score
F9277_RS15265	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F9277_RS15275	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F9277_RS15280	COG0142	geranyltranstransferase activity
F9277_RS15320	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
F9277_RS15325	COG1178	ABC-type Fe3 transport system permease component
F9277_RS15330	COG4143	(ABC) transporter
F9277_RS15335	COG0163	prenyltransferase activity
F9277_RS15340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F9277_RS15350	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F9277_RS15360	COG2105	PFAM AIG2 family protein
F9277_RS15370	COG0729	surface antigen
F9277_RS15375	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F9277_RS15385	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
F9277_RS15400	COG1136	(ABC) transporter
F9277_RS15420	COG0529	Catalyzes the synthesis of activated sulfate
F9277_RS15425	COG0471	metal ion transport
F9277_RS15425	COG3273	potassium ion transport
F9277_RS15440	COG1648	precorrin-2 dehydrogenase activity
F9277_RS15440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F9277_RS15445	COG0737	Belongs to the 5'-nucleotidase family
F9277_RS15455	COG0513	Belongs to the DEAD box helicase family
F9277_RS15460	COG2153	protein acetylation
F9277_RS15475	COG0545	Peptidyl-prolyl cis-trans isomerase
F9277_RS15485	COG0203	ribosomal protein L17
F9277_RS15490	COG0202	RNA polymerase activity
F9277_RS15500	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F9277_RS15505	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F9277_RS15510	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F9277_RS15515	COG0201	protein transport
F9277_RS15520	COG0200	Binds to the 23S rRNA
F9277_RS15525	COG1841	ribosomal large subunit assembly
F9277_RS15540	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F9277_RS15590	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
F9277_RS15610	COG0088	Forms part of the polypeptide exit tunnel
F9277_RS15625	COG0254	rRNA binding
F9277_RS15635	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F9277_RS15640	COG1609	Transcriptional regulator
F9277_RS15660	COG1575	Belongs to the MenA family. Type 1 subfamily
F9277_RS15665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F9277_RS15675	COG1494	fructose-1,6-bisphosphatase
F9277_RS15705	COG0149	triose-phosphate isomerase activity
F9277_RS15710	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
F9277_RS15720	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F9277_RS15725	COG1482	cell wall glycoprotein biosynthetic process
F9277_RS15765	COG0438	transferase activity, transferring glycosyl groups
F9277_RS15810	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9277_RS15820	COG1560	Kdo2-lipid A biosynthetic process
F9277_RS15830	COG0859	PFAM glycosyl transferase family 9
F9277_RS15835	COG1519	Transferase
F9277_RS15850	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F9277_RS15855	COG1028	Short-chain dehydrogenase reductase Sdr
F9277_RS15865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F9277_RS15895	COG3642	lipopolysaccharide core region biosynthetic process
F9277_RS15900	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F9277_RS15905	COG0859	PFAM glycosyl transferase family 9
F9277_RS15910	COG0463	Glycosyl transferase, family 2
F9277_RS15925	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
F9277_RS15940	COG2194	sulfuric ester hydrolase activity
F9277_RS15960	COG0840	transmembrane signaling receptor activity
F9277_RS15970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F9277_RS15980	COG1560	Kdo2-lipid A biosynthetic process
F9277_RS15985	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F9277_RS15990	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
F9277_RS15995	COG1561	YicC-like family, N-terminal region
F9277_RS16000	COG0745	RESPONSE REGULATOR receiver
F9277_RS16025	COG4608	Belongs to the ABC transporter superfamily
F9277_RS16030	COG0444	Belongs to the ABC transporter superfamily
F9277_RS16035	COG0747	negative chemotaxis
F9277_RS16040	COG4239	(ABC) transporter, permease
F9277_RS16045	COG4174	ABC transporter (Permease)
F9277_RS16070	COG0811	peptide transport
F9277_RS16075	COG0848	biopolymer transport protein
F9277_RS16090	COG0194	GDP metabolic process
F9277_RS16095	COG1758	RNA polymerase activity
F9277_RS16100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F9277_RS16105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9277_RS16110	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F9277_RS16120	COG2233	PERMEase
F9277_RS16140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F9277_RS16150	COG2183	response to ionizing radiation
F9277_RS16165	COG1040	competence protein
F9277_RS16175	COG0494	nUDIX hydrolase
F9277_RS16180	COG1218	3'(2'),5'-bisphosphate nucleotidase
F9277_RS16190	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
F9277_RS16195	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
F9277_RS16200	COG3156	type II secretion system protein K
F9277_RS16205	COG4795	General secretion pathway protein
F9277_RS16210	COG2165	general secretion pathway protein
F9277_RS16215	COG2165	general secretion pathway protein
F9277_RS16220	COG2165	general secretion pathway protein
F9277_RS16225	COG1459	type II secretion system
F9277_RS16230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F9277_RS16240	COG3031	protein transport across the cell outer membrane
F9277_RS16245	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F9277_RS16265	COG0456	acetyltransferase
F9277_RS16270	COG1490	D-aminoacyl-tRNA deacylase activity
F9277_RS16290	COG1217	gtp-binding protein TYPA
F9277_RS16300	COG0174	glutamine synthetase
F9277_RS16310	COG3852	Histidine kinase
F9277_RS16315	COG2204	response regulator
F9277_RS16325	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F9277_RS16355	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F9277_RS16365	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F9277_RS16365	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F9277_RS16385	COG0084	hydrolase, TatD family'
F9277_RS16390	COG0805	protein transport
F9277_RS16395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F9277_RS16410	COG3165	ubiquinone biosynthetic process from chorismate
F9277_RS16420	COG1322	Protein conserved in bacteria
F9277_RS16440	COG2081	HI0933 family
F9277_RS16450	COG1528	Iron-storage protein
F9277_RS16460	COG0589	response to stress
F9277_RS16485	COG5002	protein histidine kinase activity
F9277_RS16485	COG5001	Diguanylate cyclase
F9277_RS16490	COG1522	sequence-specific DNA binding
F9277_RS16505	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F9277_RS16515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9277_RS16520	COG0800	Aldolase
F9277_RS16525	COG2610	gluconate transmembrane transporter activity
F9277_RS16530	COG3265	gluconokinase activity
F9277_RS16535	COG0129	dihydroxy-acid dehydratase activity
F9277_RS16550	COG2076	Multidrug Resistance protein
F9277_RS16555	COG0583	DNA-binding transcription factor activity
F9277_RS16560	COG1609	Transcriptional regulator
F9277_RS16595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F9277_RS16600	COG0601	transmembrane transport
F9277_RS16605	COG0747	negative chemotaxis
F9277_RS16610	COG4172	Belongs to the ABC transporter superfamily
F9277_RS16620	COG0546	phosphoglycolate phosphatase activity
F9277_RS16665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9277_RS16670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9277_RS16680	COG2960	long-chain fatty acid transporting porin activity
F9277_RS16685	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F9277_RS16690	COG0583	DNA-binding transcription factor activity
F9277_RS16740	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F9277_RS16750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F9277_RS16765	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F9277_RS16770	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F9277_RS16775	COG0551	DNA topoisomerase type I activity
F9277_RS16785	COG0758	DNA mediated transformation
F9277_RS16795	COG0242	peptide deformylase activity
F9277_RS16805	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F9277_RS16805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F9277_RS16810	COG0569	domain protein
F9277_RS16815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F9277_RS16825	COG1272	protein, Hemolysin III
F9277_RS16830	COG4326	sporulation control protein
F9277_RS16840	COG3084	Protein conserved in bacteria
F9277_RS16850	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F9277_RS16855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F9277_RS16860	COG0204	Acyl-transferase
F9277_RS16870	COG3706	GGDEF domain
F9277_RS16875	COG0606	chelatase, subunit chli
F9277_RS16885	COG3978	acetolactate synthase activity
F9277_RS16890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F9277_RS16895	COG0129	dihydroxy-acid dehydratase activity
F9277_RS16905	COG0583	DNA-binding transcription factor activity
F9277_RS16910	COG2814	Major facilitator Superfamily
F9277_RS16920	COG0765	amino acid transport
F9277_RS16930	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F9277_RS16940	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
F9277_RS16965	COG0356	it plays a direct role in the translocation of protons across the membrane
F9277_RS16970	COG3312	ion transport
F9277_RS16975	COG1475	DNA binding
F9277_RS16980	COG1192	Involved in chromosome partitioning
F9277_RS16990	COG0445	tRNA wobble uridine modification
F9277_RS16995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F9277_RS17025	COG1126	abc transporter atp-binding protein
F9277_RS17050	COG0592	DNA-directed DNA polymerase activity
F9277_RS17060	COG0187	DNA topoisomerase II activity
F9277_RS17065	COG0071	Belongs to the small heat shock protein (HSP20) family
F9277_RS17070	COG3977	Valine--pyruvate aminotransferase
F9277_RS17075	COG0366	Alpha amylase catalytic
F9277_RS17090	COG2119	membrane
F9277_RS17100	COG0425	Belongs to the sulfur carrier protein TusA family
F9277_RS17115	COG0604	alcohol dehydrogenase
F9277_RS17120	COG0183	Belongs to the thiolase family
F9277_RS17130	COG1739	Uncharacterized protein family UPF0029
F9277_RS17135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F9277_RS17190	COG2132	Multicopper oxidase
F9277_RS17210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F9277_RS17215	COG2104	thiamine diphosphate biosynthetic process
F9277_RS17230	COG0006	proline dipeptidase activity
F9277_RS17230	COG0006	proline dipeptidase activity
F9277_RS17240	COG2814	Major facilitator Superfamily
F9277_RS17260	COG3220	belongs to the UPF0276 family
F9277_RS17270	COG0210	DNA helicase
F9277_RS17280	COG0405	Gamma-glutamyltransferase
F9277_RS17285	COG1280	lysine exporter protein (LysE YggA)
F9277_RS17295	COG2962	Rard protein
F9277_RS17300	COG0514	ATP-dependent DNA helicase (RecQ)
F9277_RS17315	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F9277_RS17330	COG3118	belongs to the thioredoxin family
F9277_RS17345	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F9277_RS17350	COG0633	Ferredoxin
F9277_RS17395	COG3071	HemY protein
F9277_RS17400	COG2959	enzyme of heme biosynthesis
F9277_RS17405	COG1587	Uroporphyrinogen-III synthase
F9277_RS17415	COG3072	Adenylate cyclase
F9277_RS17430	COG0019	diaminopimelate decarboxylase activity
F9277_RS17450	COG1011	Hydrolase
F9277_RS17455	COG3287	FIST C domain
F9277_RS17455	COG2200	EAL domain
F9277_RS17455	COG2199	diguanylate cyclase activity
F9277_RS17460	COG3148	PFAM DTW domain containing protein
F9277_RS17475	COG0561	phosphatase activity
F9277_RS17480	COG2267	carboxylic ester hydrolase activity
F9277_RS17485	COG1280	lysine exporter protein (LysE YggA)
F9277_RS17490	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
F9277_RS17495	COG0640	Transcriptional regulator
F9277_RS17500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F9277_RS17550	COG2095	MarC family integral membrane protein
F9277_RS17560	COG0742	ribosomal rna small subunit methyltransferase
F9277_RS17565	COG0552	protein localization to endoplasmic reticulum
F9277_RS17570	COG2884	Cell division ATP-binding protein ftsE
F9277_RS17575	COG2177	Part of the ABC transporter FtsEX involved in
F9277_RS17590	COG0705	Rhomboid family
F9277_RS17595	COG1580	Controls the rotational direction of flagella during chemotaxis
F9277_RS17600	COG3161	chorismate lyase activity
F9277_RS17610	COG2937	Belongs to the GPAT DAPAT family
F9277_RS17630	COG0534	Mate efflux family protein
F9277_RS17635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9277_RS17670	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
F9277_RS17675	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
F9277_RS17695	COG2003	Belongs to the UPF0758 family
F9277_RS17710	COG3339	Conserved Protein
F9277_RS17845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F9277_RS17855	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F9277_RS17905	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F9277_RS17910	COG0250	Participates in transcription elongation, termination and antitermination
F9277_RS17925	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F9277_RS17945	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
F9277_RS17950	COG2816	NAD+ diphosphatase activity
F9277_RS17970	COG1573	uracil-dna glycosylase
F9277_RS17980	COG3068	Protein conserved in bacteria
F9277_RS17985	COG1253	flavin adenine dinucleotide binding
F9277_RS18000	COG0151	Belongs to the GarS family
F9277_RS18010	COG0789	Transcriptional regulator
F9277_RS18015	COG3710	Transcriptional regulator
F9277_RS18025	COG0531	amino acid
F9277_RS18030	COG1982	Orn Lys Arg decarboxylase major
F9277_RS18075	COG3226	Transcriptional regulator
F9277_RS18080	COG0583	DNA-binding transcription factor activity
F9277_RS18095	COG0488	(ABC) transporter
F9277_RS18100	COG0435	Glutathione S-transferase
F9277_RS18105	COG0431	NADPH-dependent FMN reductase
F9277_RS18110	COG0583	DNA-binding transcription factor activity
F9277_RS18115	COG4628	conserved protein (DUF2132)
F9277_RS18120	COG0488	(ABC) transporter
F9277_RS18135	COG0346	lactoylglutathione lyase activity
F9277_RS18140	COG0384	phenazine biosynthesis protein PhzF
F9277_RS18155	COG3220	belongs to the UPF0276 family
F9277_RS18170	COG1271	oxidase subunit
F9277_RS18175	COG1294	oxidase, subunit
F9277_RS18220	COG2207	Transcriptional regulator
F9277_RS18230	COG1882	Formate acetyltransferase
F9277_RS18235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F9277_RS18240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F9277_RS18255	COG2205	protein histidine kinase activity
F9277_RS18260	COG0745	RESPONSE REGULATOR receiver
F9277_RS18270	COG0454	-acetyltransferase
F9277_RS18280	COG2814	Major facilitator Superfamily
F9277_RS18295	COG0583	DNA-binding transcription factor activity
F9277_RS18300	COG2988	succinylglutamate desuccinylase activity
F9277_RS18340	COG0628	permease
F9277_RS18345	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
F9277_RS18360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F9277_RS18370	COG4628	conserved protein (DUF2132)
F9277_RS18375	COG0583	DNA-binding transcription factor activity
F9277_RS18400	COG1686	Belongs to the peptidase S11 family
F9277_RS18415	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F9277_RS18435	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F9277_RS18440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F9277_RS18455	COG0415	Belongs to the DNA photolyase family
F9277_RS18460	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
F9277_RS18470	COG4667	esterase of the alpha-beta hydrolase superfamily
F9277_RS18475	COG2095	MarC family integral membrane protein
F9277_RS18485	COG1596	polysaccharide export
F9277_RS18510	COG0583	DNA-binding transcription factor activity
F9277_RS18540	COG1301	dicarboxylic acid transport
F9277_RS18555	COG3339	Conserved Protein
F9277_RS18560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F9277_RS18565	COG0700	Nucleoside recognition
F9277_RS18570	COG3366	ferrous iron transmembrane transporter activity
F9277_RS18585	COG0366	Alpha amylase catalytic
F9277_RS18590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F9277_RS18595	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F9277_RS18600	COG1640	4-alpha-glucanotransferase
F9277_RS18610	COG0058	SHG alpha-glucan phosphorylase activity
F9277_RS18635	COG1999	signal sequence binding
F9277_RS18645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F9277_RS18645	COG1263	PTS System
F9277_RS18650	COG1162	GTPase activity
F9277_RS18655	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
F9277_RS18660	COG0673	inositol 2-dehydrogenase activity
F9277_RS18685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9277_RS18690	COG0673	inositol 2-dehydrogenase activity
F9277_RS18695	COG3962	Belongs to the TPP enzyme family
F9277_RS18705	COG0477	Major facilitator Superfamily
F9277_RS18705	COG2814	Major facilitator Superfamily
F9277_RS18710	COG0583	DNA-binding transcription factor activity
F9277_RS18725	COG0183	Belongs to the thiolase family
F9277_RS18755	COG0531	amino acid
F9277_RS18760	COG1982	Orn Lys Arg decarboxylase major
F9277_RS18780	COG1929	Belongs to the glycerate kinase type-1 family
F9277_RS18785	COG3835	regulator
F9277_RS18795	COG1228	amidohydrolase
F9277_RS18855	COG1132	(ABC) transporter
F9277_RS18860	COG1132	(ABC) transporter
F9277_RS18865	COG4771	TonB-dependent receptor
F9277_RS18905	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
F9277_RS18905	COG3408	Glycogen debranching enzyme
F9277_RS18925	COG2814	Major facilitator Superfamily
F9277_RS18940	COG2358	TRAP transporter, solute receptor (TAXI family
F9277_RS18945	COG3047	cAMP biosynthetic process
F9277_RS18950	COG1357	PFAM Pentapeptide repeats (8 copies)
F9277_RS18975	COG2076	Multidrug Resistance protein
F9277_RS19010	COG0583	DNA-binding transcription factor activity
F9277_RS19025	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
F9277_RS19040	COG3152	Membrane
F9277_RS19050	COG2199	diguanylate cyclase activity
F9277_RS19060	COG0561	phosphatase activity
F9277_RS19070	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F9277_RS19075	COG0564	pseudouridine synthase activity
F9277_RS19080	COG0534	Mate efflux family protein
F9277_RS19085	COG1609	Transcriptional regulator
F9277_RS19090	COG3842	ATPase activity
F9277_RS19095	COG2723	6-phospho-beta-galactosidase activity
F9277_RS19100	COG0395	ABC-type sugar transport system, permease component
F9277_RS19115	COG1609	Transcriptional regulator
F9277_RS19120	COG4580	involved in the transport of maltose and maltodextrins
F9277_RS19125	COG5001	Diguanylate cyclase
F9277_RS19190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F9277_RS19200	COG0826	peptidase U32
F9277_RS19220	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9277_RS19225	COG3716	PTS system mannose fructose sorbose family IID component
F9277_RS19235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F9277_RS19240	COG2222	sugar isomerase
F9277_RS19250	COG1349	DNA-binding transcription factor activity
F9277_RS19255	COG1349	DNA-binding transcription factor activity
F9277_RS19265	COG1136	(ABC) transporter
F9277_RS19270	COG0577	efflux transmembrane transporter activity
F9277_RS19300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F9277_RS19305	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
F9277_RS19315	COG2259	Doxx family
F9277_RS19355	COG3623	hexulose-6-phosphate isomerase
F9277_RS19360	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
F9277_RS19365	COG0561	phosphatase activity
F9277_RS19415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F9277_RS19420	COG0251	oxidation-reduction process
F9277_RS19440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F9277_RS19450	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
F9277_RS19455	COG2207	Transcriptional regulator
F9277_RS19465	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F9277_RS19470	COG0830	nickel cation binding
F9277_RS19475	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
F9277_RS19480	COG0804	urea catabolic process
F9277_RS19485	COG0832	Belongs to the urease beta subunit family
F9277_RS19490	COG0831	urea catabolic process
F9277_RS19495	COG0829	nickel cation binding
F9277_RS19510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F9277_RS19535	COG0786	glutamate:sodium symporter activity
F9277_RS19540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9277_RS19545	COG1131	(ABC) transporter
F9277_RS19560	COG0786	glutamate:sodium symporter activity
F9277_RS19585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F9277_RS19595	COG3279	Response regulator of the LytR AlgR family
F9277_RS19600	COG3275	phosphorelay sensor kinase activity
F9277_RS19620	COG1136	(ABC) transporter
F9277_RS19630	COG0583	DNA-binding transcription factor activity
F9277_RS19635	COG1566	PFAM secretion protein HlyD family protein
F9277_RS19650	COG0772	Belongs to the SEDS family
F9277_RS19675	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
F9277_RS19675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F9277_RS19685	COG0444	Belongs to the ABC transporter superfamily
F9277_RS19690	COG4608	Belongs to the ABC transporter superfamily
F9277_RS19715	COG1444	tRNA N-acetyltransferase activity
F9277_RS19720	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
F9277_RS19725	COG0848	biopolymer transport protein
F9277_RS19765	COG1595	DNA-templated transcription, initiation
F9277_RS19795	COG4166	transmembrane transport
F9277_RS19865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9277_RS19920	COG1132	(ABC) transporter
F9277_RS19935	COG0517	IMP dehydrogenase activity
F9277_RS19935	COG0516	GMP reductase activity
F9277_RS19945	COG0641	radical SAM
F9277_RS19950	COG4580	involved in the transport of maltose and maltodextrins
F9277_RS19955	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F9277_RS19965	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
F9277_RS19970	COG1028	Short-chain dehydrogenase reductase Sdr
F9277_RS19975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9277_RS19980	COG0800	Aldolase
F9277_RS19995	COG1368	sulfuric ester hydrolase activity
F9277_RS20000	COG2149	membrane
F9277_RS20025	COG2957	Belongs to the agmatine deiminase family
F9277_RS20030	COG0531	amino acid
F9277_RS20035	COG0549	Belongs to the carbamate kinase family
F9277_RS20050	COG0800	Aldolase
F9277_RS20055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9277_RS20060	COG1904	glucuronate isomerase
F9277_RS20065	COG0246	Mannitol dehydrogenase
F9277_RS20075	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F9277_RS20085	COG2186	Transcriptional regulator
F9277_RS20090	COG1312	Catalyzes the dehydration of D-mannonate
F9277_RS20095	COG3655	Transcriptional regulator
F9277_RS20110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F9277_RS20115	COG1595	DNA-templated transcription, initiation
F9277_RS20125	COG0513	Belongs to the DEAD box helicase family
F9277_RS20130	COG3713	MltA-interacting MipA family protein
F9277_RS20140	COG2153	protein acetylation
F9277_RS20145	COG2258	MOSC domain
F9277_RS20160	COG1522	sequence-specific DNA binding
F9277_RS20180	COG0346	lactoylglutathione lyase activity
F9277_RS20225	COG0366	Alpha amylase catalytic
F9277_RS20230	COG0583	DNA-binding transcription factor activity
F9277_RS20265	COG3634	alkyl hydroperoxide reductase activity
F9277_RS20280	COG1846	Transcriptional regulator
F9277_RS20285	COG1764	response to oxidative stress
F9277_RS20300	COG0840	transmembrane signaling receptor activity
F9277_RS20305	COG0612	Peptidase, M16
F9277_RS20330	COG0739	heme binding
F9277_RS20355	COG4604	ABC transporter, ATP-binding protein
F9277_RS20360	COG4605	iron ion homeostasis
F9277_RS20365	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F9277_RS20375	COG4607	ABC-type enterochelin transport system periplasmic component
F9277_RS20380	COG0583	DNA-binding transcription factor activity
F9277_RS20385	COG4771	TonB-dependent receptor
F9277_RS20405	COG2814	Major facilitator Superfamily
F9277_RS20420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F9277_RS20440	COG2203	Gaf domain
F9277_RS20440	COG2199	diguanylate cyclase activity
F9277_RS20470	COG2356	endonuclease I
F9277_RS20475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9277_RS20520	COG0456	acetyltransferase
F9277_RS20540	COG1028	Short-chain dehydrogenase reductase Sdr
F9277_RS20550	COG3005	denitrification pathway
F9277_RS20555	COG0243	molybdopterin cofactor binding
F9277_RS20560	COG0671	phosphoesterase, PA-phosphatase related
F9277_RS20575	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F9277_RS20580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9277_RS20585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9277_RS20590	COG1116	anion transmembrane transporter activity
F9277_RS20595	COG0351	phosphomethylpyrimidine kinase
F9277_RS20600	COG0312	modulator of DNA gyrase
F9277_RS20605	COG0312	modulator of DNA gyrase
F9277_RS20670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F9277_RS20680	COG0584	glycerophosphoryl diester phosphodiesterase
F9277_RS20685	COG0039	L-malate dehydrogenase activity
F9277_RS20690	COG0745	RESPONSE REGULATOR receiver
F9277_RS20710	COG0811	peptide transport
F9277_RS20715	COG0811	peptide transport
F9277_RS20720	COG0848	biopolymer transport protein
F9277_RS20765	COG0803	Belongs to the bacterial solute-binding protein 9 family
F9277_RS20770	COG1121	(ABC) transporter
F9277_RS20775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F9277_RS20790	COG1770	oligopeptidase
F9277_RS20795	COG2814	Major facilitator Superfamily
F9277_RS20800	COG0010	Belongs to the arginase family
F9277_RS20805	COG1166	arginine decarboxylase activity
F9277_RS20815	COG0189	ligase activity
F9277_RS20815	COG4067	protein conserved in archaea
F9277_RS20820	COG0189	ligase activity
F9277_RS20845	COG0583	DNA-binding transcription factor activity
F9277_RS20885	COG1114	Component of the transport system for branched-chain amino acids
F9277_RS20910	COG0579	oxidoreductase
F9277_RS20925	COG3033	Beta-eliminating lyase
F9277_RS20945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F9277_RS20950	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
F9277_RS20970	COG3706	GGDEF domain
F9277_RS20985	COG3706	GGDEF domain
F9277_RS20990	COG0415	Belongs to the DNA photolyase family
F9277_RS20995	COG3046	protein related to deoxyribodipyrimidine photolyase
F9277_RS21010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F9277_RS21010	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F9277_RS21015	COG1765	OsmC-like protein
F9277_RS21065	COG1011	Hydrolase
F9277_RS21100	COG3240	lipase activity
F9277_RS21130	COG1609	Transcriptional regulator
F9277_RS21140	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F9277_RS21150	COG1840	ABC-type Fe3 transport system, periplasmic component
F9277_RS21155	COG3842	ATPase activity
F9277_RS21180	COG2990	Protein conserved in bacteria
F9277_RS21190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F9277_RS21195	COG2866	Carboxypeptidase
F9277_RS21205	COG0583	DNA-binding transcription factor activity
F9277_RS21230	COG3104	oligopeptide transport
F9277_RS21235	COG1760	l-serine dehydratase
F9277_RS21260	COG0741	lytic transglycosylase activity
F9277_RS21260	COG1388	LysM domain
F9277_RS21280	COG1815	bacterial-type flagellum-dependent cell motility
F9277_RS21285	COG1558	bacterial-type flagellum-dependent cell motility
F9277_RS21295	COG1749	Flagellar hook protein flgE
F9277_RS21300	COG4787	bacterial-type flagellum-dependent cell motility
F9277_RS21305	COG4786	Flagellar basal body rod
F9277_RS21310	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
F9277_RS21315	COG1706	bacterial-type flagellum-dependent cell motility
F9277_RS21325	COG1256	bacterial-type flagellum assembly
F9277_RS21325	COG4786	Flagellar basal body rod
F9277_RS21330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F9277_RS21365	COG2226	methyltransferase
F9277_RS21385	COG0672	)-iron permease
F9277_RS21400	COG0577	efflux transmembrane transporter activity
F9277_RS21400	COG1136	(ABC) transporter
F9277_RS21410	COG1136	(ABC) transporter
F9277_RS21425	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F9277_RS21475	COG1360	Flagellar Motor Protein
F9277_RS21480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F9277_RS21485	COG1191	sigma factor activity
F9277_RS21490	COG1580	Controls the rotational direction of flagella during chemotaxis
F9277_RS21505	COG1516	flagellar protein fliS
F9277_RS21510	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
F9277_RS21520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F9277_RS21535	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F9277_RS21545	COG1987	bacterial-type flagellum assembly
F9277_RS21605	COG2200	EAL domain
F9277_RS21650	COG0346	lactoylglutathione lyase activity
F9277_RS21675	COG0745	RESPONSE REGULATOR receiver
F9277_RS21700	COG0156	8-amino-7-oxononanoate synthase activity
F9277_RS21705	COG1063	alcohol dehydrogenase
F9277_RS21720	COG0583	DNA-binding transcription factor activity
F9277_RS21760	COG3338	carbonate dehydratase activity
F9277_RS21790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F9277_RS21800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9277_RS21810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9277_RS21850	COG0318	PFAM AMP-dependent synthetase and ligase
F9277_RS21855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9277_RS21890	COG0786	glutamate:sodium symporter activity
F9277_RS21895	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F9277_RS21900	COG1538	Outer membrane efflux protein
F9277_RS21910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9277_RS21915	COG0583	DNA-binding transcription factor activity
F9277_RS21930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F9277_RS21935	COG2197	response regulator
F9277_RS21945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F9277_RS21945	COG0574	Belongs to the PEP-utilizing enzyme family
F9277_RS21955	COG0252	asparaginase activity
F9277_RS21965	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F9277_RS21970	COG0583	DNA-binding transcription factor activity
F9277_RS21990	COG3122	Protein conserved in bacteria
F9277_RS22005	COG1902	pentaerythritol trinitrate reductase activity
F9277_RS22015	COG2814	Major facilitator Superfamily
F9277_RS22020	COG1028	Short-chain dehydrogenase reductase Sdr
F9277_RS22045	COG0583	DNA-binding transcription factor activity
F9277_RS22055	COG0513	Belongs to the DEAD box helicase family
F9277_RS22075	COG0095	Lipoate-protein ligase
F9277_RS22095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9277_RS22100	COG2207	Transcriptional regulator
F9277_RS22100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F9277_RS22105	COG0583	DNA-binding transcription factor activity
F9277_RS22115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F9277_RS22150	COG1566	PFAM secretion protein HlyD family protein
F9277_RS22155	COG0583	DNA-binding transcription factor activity
F9277_RS22170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9277_RS22170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9277_RS22170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9277_RS22175	COG2207	Transcriptional regulator
F9277_RS22185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9277_RS22190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9277_RS22195	COG0583	DNA-binding transcription factor activity
F9277_RS22205	COG2084	Dehydrogenase
F9277_RS22210	COG0753	catalase activity
F9277_RS22220	COG2130	NADP-dependent
F9277_RS22225	COG1309	transcriptional regulator
F9277_RS22260	COG0438	transferase activity, transferring glycosyl groups
F9277_RS22270	COG3206	protein involved in exopolysaccharide biosynthesis
F9277_RS22270	COG0489	protein tyrosine kinase activity
F9277_RS22285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F9277_RS22290	COG3842	ATPase activity
F9277_RS22305	COG1175	transmembrane transport
F9277_RS22310	COG3833	ABC-type maltose transport systems, permease component
F9277_RS22355	COG0741	lytic transglycosylase activity
F9277_RS22380	COG2354	Protein conserved in bacteria
F9277_RS22395	COG0401	homolog of Blt101
F9277_RS22400	COG3217	Mosc domain protein beta barrel domain protein
F9277_RS22400	COG3217	Mosc domain protein beta barrel domain protein
F9277_RS22400	COG0633	Ferredoxin
F9277_RS22400	COG0633	Ferredoxin
F9277_RS22410	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
F9277_RS22450	COG0583	DNA-binding transcription factor activity
F9277_RS22480	COG1335	isochorismatase
F9277_RS22485	COG4977	sequence-specific DNA binding
F9277_RS22495	COG2194	sulfuric ester hydrolase activity
F9277_RS22500	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F9277_RS22510	COG2205	protein histidine kinase activity
F9277_RS22515	COG0745	RESPONSE REGULATOR receiver
F9277_RS22520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9277_RS22525	COG4948	Mandelate Racemase Muconate Lactonizing
F9277_RS22530	COG3976	FMN-binding domain protein
F9277_RS22530	COG1053	succinate dehydrogenase
F9277_RS22545	COG4221	oxidoreductase activity
F9277_RS22560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F9277_RS22580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F9277_RS22590	COG2814	Major facilitator Superfamily
F9277_RS22605	COG1418	mRNA catabolic process
F9277_RS22620	COG0402	S-adenosylhomocysteine deaminase activity
F9277_RS22625	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F9277_RS22630	COG2239	Acts as a magnesium transporter
F9277_RS22635	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F9277_RS22640	COG1566	PFAM secretion protein HlyD family protein
F9277_RS22665	COG0745	RESPONSE REGULATOR receiver
F9277_RS22670	COG2205	protein histidine kinase activity
F9277_RS22680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9277_RS22685	COG0531	amino acid
F9277_RS22690	COG1522	sequence-specific DNA binding
F9277_RS22700	COG0583	DNA-binding transcription factor activity
F9277_RS22720	COG2205	protein histidine kinase activity
F9277_RS22720	COG0784	Response regulator, receiver
F9277_RS22720	COG5002	protein histidine kinase activity
F9277_RS22725	COG0673	inositol 2-dehydrogenase activity
F9277_RS22730	COG0534	Mate efflux family protein
F9277_RS22735	COG2926	Belongs to the UPF0265 family
F9277_RS22805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F9277_RS22810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F9277_RS22820	COG1280	lysine exporter protein (LysE YggA)
F9277_RS22830	COG0183	Belongs to the thiolase family
F9277_RS22855	COG3005	denitrification pathway
F9277_RS22875	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F9277_RS22880	COG3850	Histidine kinase
F9277_RS22885	COG2197	response regulator
F9277_RS22900	COG2195	Cleaves the N-terminal amino acid of tripeptides
F9277_RS22920	COG0840	transmembrane signaling receptor activity
F9277_RS22930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F9277_RS22960	COG0545	Peptidyl-prolyl cis-trans isomerase
F9277_RS22970	COG2885	chlorophyll binding
F9277_RS22990	COG1278	Cold shock
F9277_RS22995	COG3036	rescue of stalled ribosome
F9277_RS23005	COG2199	diguanylate cyclase activity
F9277_RS23025	COG0577	efflux transmembrane transporter activity
F9277_RS23025	COG1136	(ABC) transporter
F9277_RS23055	COG1538	Outer membrane efflux protein
F9277_RS23060	COG2205	protein histidine kinase activity
F9277_RS23060	COG0784	Response regulator, receiver
F9277_RS23085	COG0840	transmembrane signaling receptor activity
F9277_RS23090	COG0783	Belongs to the Dps family
F9277_RS23100	COG1619	proteins homologs of microcin C7 resistance protein MccF
F9277_RS23105	COG2133	pyrroloquinoline quinone binding
F9277_RS23110	COG1454	alcohol dehydrogenase
F9277_RS23120	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
F9277_RS23140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F9277_RS23145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9277_RS23155	COG3186	Phenylalanine-4-hydroxylase
F9277_RS23190	COG3530	Putative quorum-sensing-regulated virulence factor
F9277_RS23225	COG1289	transmembrane transporter activity
F9277_RS23230	COG0210	DNA helicase
F9277_RS23240	COG1879	ABC-type sugar transport system periplasmic component
F9277_RS23245	COG0784	Response regulator, receiver
F9277_RS23245	COG2205	protein histidine kinase activity
F9277_RS23245	COG2198	Histidine kinase
F9277_RS23275	COG3119	arylsulfatase activity
F9277_RS23280	COG3119	arylsulfatase activity
F9277_RS23290	COG0714	Associated with various cellular activities
F9277_RS23350	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
F9277_RS23360	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F9277_RS23370	COG0583	DNA-binding transcription factor activity
F9277_RS23375	COG1597	lipid kinase activity
F9277_RS23380	COG3111	PFAM Bacterial OB fold (BOF) protein
F9277_RS23400	COG0641	radical SAM
F9277_RS23425	COG0501	Belongs to the peptidase M48B family
F9277_RS23430	COG1704	LemA family
F9277_RS23435	COG3069	C4-dicarboxylate transmembrane transporter activity
F9277_RS23465	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
F9277_RS23470	COG0739	heme binding
F9277_RS23490	COG2885	chlorophyll binding
F9277_RS23510	COG3501	Rhs element vgr protein
F9277_RS23535	COG0515	serine threonine protein kinase
F9277_RS23570	COG1522	sequence-specific DNA binding
F9277_RS23630	COG0457	Tetratricopeptide repeat
F9277_RS23635	COG2814	Major facilitator Superfamily
F9277_RS23635	COG0477	Major facilitator Superfamily
F9277_RS23640	COG1940	carbohydrate kinase activity
F9277_RS23645	COG2017	converts alpha-aldose to the beta-anomer
F9277_RS23650	COG0019	diaminopimelate decarboxylase activity
F9277_RS23655	COG4264	IucA IucC family
F9277_RS23680	COG4772	TonB-dependent receptor
F9277_RS23685	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
F9277_RS23690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F9277_RS23695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F9277_RS23700	COG1120	ATPase activity
F9277_RS23705	COG4771	TonB-dependent receptor
F9277_RS23720	COG2205	protein histidine kinase activity
F9277_RS23720	COG0784	Response regulator, receiver
F9277_RS23725	COG5001	Diguanylate cyclase
F9277_RS23725	COG3300	MHYT domain
F9277_RS23730	COG2197	response regulator
F9277_RS23735	COG3706	GGDEF domain
F9277_RS23745	COG2197	response regulator
F9277_RS23755	COG0778	Nitroreductase
F9277_RS23765	COG0784	Response regulator, receiver
F9277_RS23765	COG0835	chemotaxis
F9277_RS23770	COG2165	general secretion pathway protein
F9277_RS23780	COG2962	Rard protein
F9277_RS23805	COG3278	Belongs to the heme-copper respiratory oxidase family
F9277_RS23845	COG1024	Enoyl-CoA hydratase
F9277_RS23850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F9277_RS23855	COG1960	acyl-CoA dehydrogenase activity
F9277_RS23870	COG0183	Belongs to the thiolase family
F9277_RS23885	COG1024	Enoyl-CoA hydratase
F9277_RS23890	COG1024	Enoyl-CoA hydratase
F9277_RS23900	COG1028	Short-chain dehydrogenase reductase Sdr
F9277_RS23910	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F9277_RS23915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F9277_RS23920	COG1845	cytochrome c oxidase, subunit III
F9277_RS23925	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F9277_RS23940	COG1902	pentaerythritol trinitrate reductase activity
F9277_RS23940	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9277_RS23945	COG0671	phosphoesterase, PA-phosphatase related
F9277_RS23965	COG2076	Multidrug Resistance protein
F9277_RS23995	COG1132	(ABC) transporter
F9277_RS24010	COG1733	regulation of RNA biosynthetic process
F9277_RS24020	COG2176	DNA-directed DNA polymerase activity
F9277_RS24185	COG0556	nucleotide-excision repair
F9277_RS24195	COG0509	glycine decarboxylation via glycine cleavage system
F9277_RS24200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F9277_RS24210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F9277_RS24220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9277_RS24225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9277_RS24255	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F9277_RS24255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9277_RS24255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9277_RS24260	COG1105	Belongs to the carbohydrate kinase PfkB family
F9277_RS24265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9277_RS24265	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9277_RS24270	COG1609	Transcriptional regulator
F9277_RS24285	COG2203	Gaf domain
F9277_RS24285	COG2200	EAL domain
F9277_RS24285	COG2199	diguanylate cyclase activity
F9277_RS24290	COG0765	amino acid transport
F9277_RS24295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9277_RS24300	COG0765	amino acid transport
F9277_RS24305	COG1126	abc transporter atp-binding protein
F9277_RS24315	COG1979	alcohol dehydrogenase
F9277_RS24320	COG2207	Transcriptional regulator
F9277_RS24330	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
F9277_RS24340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9277_RS24355	COG3437	response regulator, receiver
F9277_RS24355	COG0784	Response regulator, receiver
F9277_RS24360	COG0546	phosphoglycolate phosphatase activity
F9277_RS24385	COG0513	Belongs to the DEAD box helicase family
F9277_RS24390	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F9277_RS24405	COG3038	cytochrome b561
F9277_RS24415	COG2116	formate transmembrane transporter activity
F9277_RS24425	COG0583	DNA-binding transcription factor activity
F9277_RS24435	COG3593	DNA synthesis involved in DNA repair
F9277_RS24440	COG0737	Belongs to the 5'-nucleotidase family
F9277_RS24460	COG1410	methionine synthase
F9277_RS24460	COG0646	methionine synthase
F9277_RS24475	COG2267	carboxylic ester hydrolase activity
F9277_RS24480	COG2067	long-chain fatty acid transport protein
F9277_RS24495	COG2050	protein possibly involved in aromatic compounds catabolism
F9277_RS24530	COG0484	heat shock protein binding
F9277_RS24540	COG3300	MHYT domain
F9277_RS24540	COG5001	Diguanylate cyclase
F9277_RS24545	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F9277_RS24555	COG4181	ATPase activity
F9277_RS24560	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F9277_RS24570	COG1984	allophanate hydrolase subunit 2
F9277_RS24575	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F9277_RS24585	COG5001	Diguanylate cyclase
F9277_RS24585	COG3447	MASE1 domain protein
F9277_RS24585	COG5002	protein histidine kinase activity
F9277_RS24590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F9277_RS24605	COG0583	DNA-binding transcription factor activity
F9277_RS24615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F9277_RS24615	COG1042	CoA-binding domain protein
F9277_RS24615	COG0045	succinate-CoA ligase (ADP-forming) activity
F9277_RS24635	COG0023	Translation Initiation Factor
F9277_RS24645	COG0544	peptidyl-prolyl cis-trans isomerase activity
F9277_RS24660	COG3140	Belongs to the UPF0181 family
F9277_RS24685	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F9277_RS24690	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F9277_RS24705	COG3706	GGDEF domain
F9277_RS24720	COG5001	Diguanylate cyclase
F9277_RS24720	COG4251	negative regulation of phosphorylation
F9277_RS24720	COG3706	GGDEF domain
F9277_RS24720	COG2203	Gaf domain
F9277_RS24730	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
F9277_RS24735	COG4149	molybdate abc transporter
F9277_RS24740	COG0725	ABC transporter, periplasmic molybdate-binding protein
F9277_RS24750	COG3111	PFAM Bacterial OB fold (BOF) protein
F9277_RS24760	COG0189	ligase activity
F9277_RS24760	COG4067	protein conserved in archaea
F9277_RS24775	COG0534	Mate efflux family protein
F9277_RS24780	COG0602	queuosine metabolic process
F9277_RS24785	COG1328	CTP reductase activity
F9277_RS24845	COG2197	response regulator
F9277_RS24850	COG3851	Histidine kinase
F9277_RS24855	COG2271	Major facilitator Superfamily
F9277_RS24860	COG1482	cell wall glycoprotein biosynthetic process
F9277_RS24870	COG0628	permease
F9277_RS24880	COG1566	PFAM secretion protein HlyD family protein
F9277_RS24905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F9277_RS24910	COG3118	belongs to the thioredoxin family
F9277_RS24920	COG2205	protein histidine kinase activity
F9277_RS24920	COG0745	RESPONSE REGULATOR receiver
F9277_RS24920	COG3292	Two component regulator propeller
F9277_RS24955	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F9277_RS24975	COG2116	formate transmembrane transporter activity
F9277_RS24985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9277_RS24990	COG2199	diguanylate cyclase activity
F9277_RS25080	COG0277	FAD linked oxidase domain protein
F9277_RS25085	COG0583	DNA-binding transcription factor activity
F9277_RS25095	COG2425	protein containing a von Willebrand factor type A (vWA) domain
F9277_RS25110	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
F9277_RS25120	COG1288	antiporter activity
F9277_RS25130	COG2814	Major facilitator Superfamily
F9277_RS25140	COG3040	lipid binding
F9277_RS25175	COG3469	chitinase activity
F9277_RS25185	COG0419	ATPase involved in DNA repair
F9277_RS25190	COG0420	3'-5' exonuclease activity
F9277_RS25215	COG3209	COG3209 Rhs family protein
F9277_RS25285	COG0631	protein serine/threonine phosphatase activity
F9277_RS25320	COG2815	serine threonine protein kinase
F9277_RS25320	COG0515	serine threonine protein kinase
F9277_RS25345	COG0346	lactoylglutathione lyase activity
F9277_RS25350	COG1902	pentaerythritol trinitrate reductase activity
F9277_RS25360	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F9277_RS25360	COG2755	lipolytic protein G-D-S-L family
F9277_RS25370	COG5642	Protein of unknown function (DUF2384)
F9277_RS25385	COG1234	tRNA 3'-trailer cleavage
F9277_RS25390	COG2067	long-chain fatty acid transport protein
F9277_RS25470	COG1024	Enoyl-CoA hydratase
F9277_RS25475	COG0628	permease
F9277_RS25500	COG3038	cytochrome b561
F9277_RS25510	COG0739	heme binding
F9277_RS25560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9277_RS25560	COG2146	nitrite reductase [NAD(P)H] activity
F9277_RS25565	COG1116	anion transmembrane transporter activity
F9277_RS25570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9277_RS25575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9277_RS25575	COG1116	anion transmembrane transporter activity
F9277_RS25585	COG3707	response regulator
F9277_RS25605	COG0243	molybdopterin cofactor binding
F9277_RS25610	COG0456	acetyltransferase
F9277_RS25615	COG5001	Diguanylate cyclase
F9277_RS25615	COG5002	protein histidine kinase activity
F9277_RS25620	COG0814	amino acid
F9277_RS25630	COG3706	GGDEF domain
F9277_RS25650	COG1785	Belongs to the alkaline phosphatase family
F9277_RS25665	COG0745	RESPONSE REGULATOR receiver
F9277_RS25695	COG2847	Copper chaperone PCu(A)C
F9277_RS25700	COG0443	Heat shock 70 kDa protein
F9277_RS25750	COG3976	FMN-binding domain protein
F9277_RS25750	COG0431	NADPH-dependent FMN reductase
F9277_RS25750	COG1053	succinate dehydrogenase
F9277_RS25775	COG4160	amino acid transport
F9277_RS25780	COG4215	(ABC) transporter
F9277_RS25785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9277_RS25790	COG1126	abc transporter atp-binding protein
F9277_RS25825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9277_RS25835	COG1012	belongs to the aldehyde dehydrogenase family
F9277_RS25845	COG0583	DNA-binding transcription factor activity
F9277_RS25850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F9277_RS25860	COG0513	Belongs to the DEAD box helicase family
F9277_RS25895	COG0582	viral genome integration into host DNA
F9277_RS25920	COG1401	restriction endodeoxyribonuclease activity
F9277_RS25945	COG0732	type I restriction modification DNA specificity domain
F9277_RS25955	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
F9277_RS26005	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
F9277_RS26025	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
F9277_RS26040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F9277_RS26055	COG2205	protein histidine kinase activity
F9277_RS26060	COG0745	RESPONSE REGULATOR receiver
F9277_RS26065	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
F9277_RS26070	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
F9277_RS26080	COG1119	ATPase activity
F9277_RS26085	COG2200	EAL domain
F9277_RS26085	COG2771	luxR family
F9277_RS26105	COG0513	Belongs to the DEAD box helicase family
F9277_RS26110	COG5001	Diguanylate cyclase
F9277_RS26110	COG5002	protein histidine kinase activity
F9277_RS26110	COG3447	MASE1 domain protein
F9277_RS26115	COG0523	cobalamin synthesis protein
F9277_RS26140	COG4206	TonB-dependent receptor
F9277_RS26150	COG0789	Transcriptional regulator
F9277_RS26155	COG4604	ABC transporter, ATP-binding protein
F9277_RS26160	COG4605	iron ion homeostasis
F9277_RS26165	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F9277_RS26170	COG4607	ABC-type enterochelin transport system periplasmic component
F9277_RS26185	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
F9277_RS26200	COG1609	Transcriptional regulator
F9277_RS26205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9277_RS26210	COG1879	ABC-type sugar transport system periplasmic component
F9277_RS26215	COG1172	Belongs to the binding-protein-dependent transport system permease family
F9277_RS26220	COG1129	ABC transporter
F9277_RS26230	COG5001	Diguanylate cyclase
F9277_RS26235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F9277_RS26240	COG1794	racemase activity, acting on amino acids and derivatives
F9277_RS26265	COG0586	Pfam SNARE associated Golgi protein
F9277_RS26305	COG0784	Response regulator, receiver
F9277_RS26305	COG2205	protein histidine kinase activity
F9277_RS26315	COG2205	protein histidine kinase activity
F9277_RS26315	COG0784	Response regulator, receiver
F9277_RS26335	COG0330	HflC and HflK could
F9277_RS26350	COG4175	Glycine betaine
F9277_RS26350	COG0517	IMP dehydrogenase activity
F9277_RS26355	COG4176	ABC-type proline glycine betaine transport system permease component
F9277_RS26395	COG0402	S-adenosylhomocysteine deaminase activity
F9277_RS26410	COG0204	Acyl-transferase
F9277_RS26440	COG2885	chlorophyll binding
F9277_RS26480	COG0455	bacterial-type flagellum organization
F9277_RS26490	COG4964	Belongs to the GSP D family
F9277_RS26510	COG0583	DNA-binding transcription factor activity
F9277_RS26515	COG1073	alpha beta
F9277_RS26530	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F9277_RS26530	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F9277_RS26545	COG4989	oxidoreductase activity
F9277_RS26570	COG1914	H( )-stimulated, divalent metal cation uptake system
F9277_RS26595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F9277_RS26615	COG2897	thiosulfate sulfurtransferase activity
F9277_RS26645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F9277_RS26655	COG2814	Major facilitator Superfamily
F9277_RS26660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F9277_RS26680	COG1612	heme a metabolic process
F9277_RS26700	COG1845	cytochrome c oxidase, subunit III
F9277_RS26705	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
F9277_RS26720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F9277_RS26730	COG1280	lysine exporter protein (LysE YggA)
F9277_RS26750	COG0179	Fumarylacetoacetate (FAA) hydrolase
F9277_RS26765	COG0697	spore germination
F9277_RS26785	COG2814	Major facilitator Superfamily
F9277_RS26790	COG0583	DNA-binding transcription factor activity
F9277_RS26795	COG5001	Diguanylate cyclase
F9277_RS26800	COG0739	heme binding
F9277_RS26825	COG3314	Sporulation integral membrane protein YlbJ
F9277_RS26840	COG0814	amino acid
F9277_RS26860	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
F9277_RS26865	COG1072	(Pantothenic acid kinase))
F9277_RS26875	COG1063	alcohol dehydrogenase
F9277_RS26880	COG2213	PTS system mannitol-specific
F9277_RS26885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9277_RS26890	COG2188	Transcriptional regulator
F9277_RS26895	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9277_RS26895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9277_RS26895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9277_RS26900	COG0383	alpha-mannosidase activity
F9277_RS26905	COG1482	cell wall glycoprotein biosynthetic process
F9277_RS26910	COG0747	negative chemotaxis
F9277_RS26920	COG1733	regulation of RNA biosynthetic process
F9277_RS26935	COG0798	PFAM Bile acid sodium symporter
F9277_RS26950	COG1881	PFAM PEBP family protein
F9277_RS26960	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9277_RS26975	COG0583	DNA-binding transcription factor activity
F9277_RS27030	COG0366	Alpha amylase catalytic
F9277_RS27045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9277_RS27050	COG0784	Response regulator, receiver
F9277_RS27050	COG0835	chemotaxis
F9277_RS27060	COG0748	coenzyme F420 binding
F9277_RS27065	COG3721	Heme iron utilization protein
F9277_RS27075	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
F9277_RS27080	COG0811	peptide transport
F9277_RS27085	COG0848	biopolymer transport protein
F9277_RS27095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F9277_RS27100	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
F9277_RS27105	COG0840	transmembrane signaling receptor activity
F9277_RS27115	COG1131	(ABC) transporter
F9277_RS27120	COG0842	Transport permease protein
F9277_RS27125	COG0251	oxidation-reduction process
F9277_RS27140	COG0800	Aldolase
F9277_RS27145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9277_RS27150	COG4145	pantothenate transmembrane transporter activity
F9277_RS27160	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
F9277_RS27185	COG3383	formate dehydrogenase (NAD+) activity
F9277_RS27205	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9277_RS27225	COG0456	acetyltransferase
F9277_RS27245	COG0612	Peptidase, M16
F9277_RS27250	COG4178	(ABC) transporter
F9277_RS27255	COG4771	TonB-dependent receptor
F9277_RS27265	COG0811	peptide transport
F9277_RS27270	COG0811	peptide transport
F9277_RS27275	COG0848	biopolymer transport protein
F9277_RS27300	COG1858	cytochrome C peroxidase
F9277_RS27310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F9277_RS27320	COG1505	serine-type exopeptidase activity
F9277_RS27325	COG0488	(ABC) transporter
F9277_RS27330	COG1720	tRNA m6t6A37 methyltransferase activity
F9277_RS27350	COG2814	Major facilitator Superfamily
F9277_RS27365	COG0583	DNA-binding transcription factor activity
F9277_RS27370	COG0589	response to stress
F9277_RS27395	COG1175	transmembrane transport
F9277_RS27400	COG0395	ABC-type sugar transport system, permease component
F9277_RS27405	COG3842	ATPase activity
F9277_RS27435	COG0523	cobalamin synthesis protein
F9277_RS27445	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F9277_RS27455	COG4667	esterase of the alpha-beta hydrolase superfamily
F9277_RS27465	COG1741	Belongs to the pirin family
F9277_RS27470	COG1278	Cold shock
F9277_RS27485	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F9277_RS27515	COG2226	methyltransferase
F9277_RS27525	COG3706	GGDEF domain
F9277_RS27530	COG1686	Belongs to the peptidase S11 family
F9277_RS27540	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9277_RS27545	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9277_RS27550	COG0583	DNA-binding transcription factor activity
F9277_RS27555	COG0625	glutathione transferase activity
F9277_RS27565	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F9277_RS27575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F9277_RS27610	COG1028	Short-chain dehydrogenase reductase Sdr
F9277_RS27635	COG3746	phosphate-selective porin O and P
F9277_RS27650	COG1028	Short-chain dehydrogenase reductase Sdr
F9277_RS27660	COG1301	dicarboxylic acid transport
F9277_RS27665	COG1252	NADH dehydrogenase
F9277_RS27675	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
F9277_RS27680	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F9277_RS27715	COG1028	Short-chain dehydrogenase reductase Sdr
F9277_RS27720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F9277_RS27730	COG0573	inorganic phosphate transmembrane transporter activity
F9277_RS27740	COG4191	Histidine kinase
F9277_RS27750	COG0110	maltose O-acetyltransferase activity
F9277_RS27785	COG0840	transmembrane signaling receptor activity
F9277_RS27790	COG0714	Associated with various cellular activities
F9277_RS27810	COG2304	oxidoreductase activity
F9277_RS27825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F9277_RS27830	COG0581	inorganic phosphate transmembrane transporter activity
F9277_RS27835	COG0573	inorganic phosphate transmembrane transporter activity
F9277_RS27845	COG0840	transmembrane signaling receptor activity
F9277_RS27870	COG1770	oligopeptidase
F9277_RS27880	COG0513	Belongs to the DEAD box helicase family
F9277_RS27890	COG1388	LysM domain
F9277_RS27890	COG1376	ErfK ybiS ycfS ynhG family protein
F9277_RS27895	COG0415	Belongs to the DNA photolyase family
F9277_RS27900	COG0789	Transcriptional regulator
F9277_RS27905	COG3272	Protein of unknown function (DUF1722)
F9277_RS27915	COG0813	purine-nucleoside phosphorylase activity
F9277_RS27945	COG1566	PFAM secretion protein HlyD family protein
F9277_RS27955	COG1122	ATPase activity
F9277_RS27975	COG0348	domain, Protein
F9277_RS27980	COG0437	4 iron, 4 sulfur cluster binding
F9277_RS27985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F9277_RS28015	COG1067	ATP-dependent peptidase activity
F9277_RS28025	COG4172	Belongs to the ABC transporter superfamily
F9277_RS28030	COG1505	serine-type exopeptidase activity
F9277_RS28035	COG0583	DNA-binding transcription factor activity
F9277_RS28040	COG1620	l-lactate permease
F9277_RS28045	COG1304	FMN binding
F9277_RS28055	COG0668	transmembrane transport
F9277_RS28070	COG4948	Mandelate Racemase Muconate Lactonizing
F9277_RS28080	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F9277_RS28100	COG1342	Belongs to the UPF0251 family
F9277_RS28110	COG4176	ABC-type proline glycine betaine transport system permease component
F9277_RS28115	COG3448	diguanylate cyclase activity
F9277_RS28115	COG4175	Glycine betaine
F9277_RS28130	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F9277_RS28135	COG0589	response to stress
F9277_RS28140	COG0583	DNA-binding transcription factor activity
F9277_RS28190	COG1335	isochorismatase
F9277_RS28205	COG0753	catalase activity
F9277_RS28230	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F9277_RS28235	COG1263	PTS System
F9277_RS28235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F9277_RS28240	COG1609	Transcriptional regulator
F9277_RS28245	COG1349	DNA-binding transcription factor activity
F9277_RS28250	COG0346	lactoylglutathione lyase activity
F9277_RS28255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F9277_RS28255	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F9277_RS28265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F9277_RS28265	COG1263	PTS System
F9277_RS28270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F9277_RS28275	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
F9277_RS28280	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F9277_RS28290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F9277_RS28305	COG0561	phosphatase activity
F9277_RS28320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9277_RS28325	COG3537	Alpha-1,2-mannosidase
F9277_RS28330	COG3537	Alpha-1,2-mannosidase
F9277_RS28340	COG3537	Alpha-1,2-mannosidase
F9277_RS28345	COG3537	Alpha-1,2-mannosidase
F9277_RS28360	COG1280	lysine exporter protein (LysE YggA)
F9277_RS28365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F9277_RS28380	COG3226	Transcriptional regulator
F9277_RS28385	COG0583	DNA-binding transcription factor activity
F9277_RS28400	COG0488	(ABC) transporter
F9277_RS28405	COG0435	Glutathione S-transferase
F9277_RS28410	COG0431	NADPH-dependent FMN reductase
F9277_RS28415	COG0583	DNA-binding transcription factor activity
F9277_RS28420	COG4628	conserved protein (DUF2132)
F9277_RS28425	COG0488	(ABC) transporter
F9277_RS28440	COG0346	lactoylglutathione lyase activity