locus-tag	class	description
GPX85_RS00045	ENOG4108MIC	Mg-protoporphyrin IX methyl transferase
GPX85_RS00065	ENOG4105EKQ	RNA-directed DNA polymerase
GPX85_RS00165	ENOG4105K34	Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound
GPX85_RS00220	ENOG4108WF3	methyltransferase
GPX85_RS00235	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GPX85_RS00250	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GPX85_RS00255	ENOG41082NX	50s ribosomal protein l35
GPX85_RS00260	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GPX85_RS00265	ENOG4105C22	threonyL-tRNA synthetase
GPX85_RS00270	ENOG4105C1J	atp-dependent rna helicase
GPX85_RS00280	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
GPX85_RS00325	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPX85_RS00335	ENOG4105CZK	Aspartate kinase
GPX85_RS00340	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
GPX85_RS00345	ENOG4108JPW	Aminotransferase
GPX85_RS00350	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
GPX85_RS00355	ENOG41090A4	Pterin carbinolamine dehydratase
GPX85_RS00360	ENOG4105MIR	Phenylalanine 4-monooxygenase
GPX85_RS00365	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GPX85_RS00370	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GPX85_RS00375	ENOG4105EGI	Transcriptional regulator
GPX85_RS00390	ENOG4108UKZ	OsmC family
GPX85_RS00395	ENOG4107YWA	deoxycytidylate deaminase
GPX85_RS00420	ENOG4105VEQ	Cold shock protein
GPX85_RS00435	ENOG4108IA2	Sodium pantothenate symporter
GPX85_RS00440	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GPX85_RS00445	ENOG4108IPW	abc transporter atp-binding protein
GPX85_RS00450	ENOG4105CM4	permease protein
GPX85_RS00455	ENOG4105DHS	permease protein
GPX85_RS00470	ENOG4105E5M	Multidrug resistance protein D
GPX85_RS00480	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GPX85_RS00490	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GPX85_RS00495	ENOG4107RGM	aldo keto reductase
GPX85_RS00505	ENOG4107T9C	Alpha amylase catalytic region
GPX85_RS00510	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GPX85_RS00515	ENOG4108M0H	Extracellular lipase
GPX85_RS00520	ENOG4105EIF	outer membrane protein W
GPX85_RS00525	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
GPX85_RS00530	ENOG4107R88	Chemotaxis protein (CheV)
GPX85_RS00535	ENOG4106TD9	Diguanylate cyclase
GPX85_RS00540	ENOG4107QP3	malate synthase g
GPX85_RS00555	ENOG4105EUB	pirin domain protein
GPX85_RS00560	ENOG4105NBK	UPF0345 protein
GPX85_RS00570	ENOG4105DAN	ATP-dependent protease
GPX85_RS00580	ENOG4105CR8	Transcriptional regulator
GPX85_RS00585	ENOG4105DAA	L-lactate
GPX85_RS00590	ENOG4105DMF	Dehydrogenase
GPX85_RS00600	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GPX85_RS00605	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
GPX85_RS00615	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
GPX85_RS00640	ENOG4105DR5	peptidase
GPX85_RS00650	ENOG4105CHH	sulfate transporter
GPX85_RS00655	ENOG4105DWD	nucleoside recognition domain protein
GPX85_RS00660	ENOG4105C1J	atp-dependent rna helicase
GPX85_RS00685	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GPX85_RS00695	ENOG4107VXZ	Hydrolase
GPX85_RS00705	ENOG4105BZU	Histidine kinase
GPX85_RS00715	ENOG4107YZP	Rhodanese domain protein
GPX85_RS00735	ENOG4108VGI	doxx family
GPX85_RS00740	ENOG4105C72	UPF0176 protein
GPX85_RS00745	ENOG4105S8Q	sugar efflux transporter
GPX85_RS00760	ENOG4106GFD	transport protein
GPX85_RS00765	ENOG41090AP	transport protein
GPX85_RS00770	ENOG4105WQ5	TonB family
GPX85_RS00785	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
GPX85_RS00790	ENOG4108I5U	Uridine phosphorylase
GPX85_RS00800	ENOG4105DU0	nucleoside hydrolase
GPX85_RS00805	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GPX85_RS00840	ENOG4107SCK	Monooxygenase
GPX85_RS00850	ENOG4108TSE	Transferase
GPX85_RS00855	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GPX85_RS00860	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
GPX85_RS00865	ENOG4105E4F	Isochorismate synthase
GPX85_RS00875	ENOG4105WQI	isochorismatase
GPX85_RS00880	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
GPX85_RS00890	ENOG4105DQ5	transport system permease protein
GPX85_RS00895	ENOG4105TVJ	transport system, permease
GPX85_RS00900	ENOG4105E0A	ABC, transporter
GPX85_RS00915	ENOG4105E93	esterase
GPX85_RS00920	ENOG4107RBR	Receptor
GPX85_RS00955	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GPX85_RS00960	ENOG4105C5I	Dehydrogenase
GPX85_RS00965	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GPX85_RS00975	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GPX85_RS00985	ENOG4105VEQ	Cold shock protein
GPX85_RS00990	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GPX85_RS00995	ENOG4108JUA	Transcriptional regulator
GPX85_RS01005	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GPX85_RS01020	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS01025	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS01030	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GPX85_RS01065	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
GPX85_RS01075	ENOG4105D9N	nucleoside
GPX85_RS01090	ENOG4105C1J	atp-dependent rna helicase
GPX85_RS01100	ENOG4105WPN	DNA integration recombination invertion protein
GPX85_RS01105	ENOG4105MZU	cell filamentation protein
GPX85_RS01115	ENOG4105BZU	Histidine kinase
GPX85_RS01120	ENOG4105VRT	cytoplasmic protein
GPX85_RS01125	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GPX85_RS01145	ENOG4105CXY	transporter
GPX85_RS01155	ENOG4105DZY	Pts system, glucitol sorbitol-specific
GPX85_RS01160	ENOG410787A	Pts system, glucitol sorbitol-specific
GPX85_RS01165	ENOG410804X	Transcriptional regulator
GPX85_RS01175	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
GPX85_RS01180	ENOG4105VI0	Pts system, glucitol sorbitol-specific
GPX85_RS01185	ENOG4105DZY	Pts system, glucitol sorbitol-specific
GPX85_RS01190	ENOG410787A	Pts system, glucitol sorbitol-specific
GPX85_RS01200	ENOG4105ETE	Transcriptional regulator (LacI family
GPX85_RS01205	ENOG4108RVA	ribokinase
GPX85_RS01210	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GPX85_RS01215	ENOG4105CNN	ABC, transporter
GPX85_RS01220	ENOG4105C2J	ABC transporter
GPX85_RS01225	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GPX85_RS01235	ENOG4105EW9	transcriptional regulator AsnC family
GPX85_RS01240	ENOG4108VP3	Lysine exporter protein (LysE YggA)
GPX85_RS01245	ENOG4105D3G	Pseudouridine synthase
GPX85_RS01255	ENOG4105DR5	peptidase
GPX85_RS01260	ENOG4105CTS	PTS system mannitol-specific
GPX85_RS01265	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
GPX85_RS01270	ENOG4105E61	Mannitol repressor protein
GPX85_RS01275	ENOG4105EP9	oxidoreductase
GPX85_RS01290	ENOG4105BZU	Histidine kinase
GPX85_RS01300	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
GPX85_RS01310	ENOG4105CBP	Major Facilitator
GPX85_RS01315	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GPX85_RS01320	ENOG4108MJ5	VirK protein
GPX85_RS01330	ENOG410814C	multidrug resistance protein
GPX85_RS01340	ENOG4105CGD	Nad-dependent epimerase dehydratase
GPX85_RS01345	ENOG4105CBN	LysR family transcriptional regulator
GPX85_RS01350	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS01360	ENOG4105C1J	atp-dependent rna helicase
GPX85_RS01365	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GPX85_RS01370	ENOG4105CK7	Sodium proline symporter
GPX85_RS01380	ENOG4105C26	Dehydrogenase
GPX85_RS01395	ENOG4105E6M	Sulphatase-modifying factor protein
GPX85_RS01400	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GPX85_RS01410	ENOG4105BZU	Histidine kinase
GPX85_RS01415	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GPX85_RS01420	ENOG4105CDY	transcriptional regulatory protein
GPX85_RS01450	ENOG4107RUE	extracellular solute-binding protein family 1
GPX85_RS01455	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
GPX85_RS01460	ENOG4107S7U	Sulfide dehydrogenase
GPX85_RS01465	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS01470	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
GPX85_RS01485	ENOG4105BZU	Histidine kinase
GPX85_RS01490	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS01495	ENOG4108YYI	Protein of unknown function (DUF2810)
GPX85_RS01500	ENOG41061ZR	Transcriptional regulator
GPX85_RS01505	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GPX85_RS01510	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
GPX85_RS01515	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GPX85_RS01525	ENOG4105C8P	)-transporter
GPX85_RS01530	ENOG4108Q67	UPF0319 protein
GPX85_RS01540	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS01555	ENOG41088SP	formiminoglutamate hydrolase
GPX85_RS01560	ENOG4105EYK	Phosphatidylglycerophosphatase B
GPX85_RS01570	ENOG4105BZ1	(ABC) transporter
GPX85_RS01580	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
GPX85_RS01585	ENOG4107W52	maltose operon periplasmic protein
GPX85_RS01595	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
GPX85_RS01605	ENOG4105YE1	PilZ domain
GPX85_RS01610	ENOG4106TD9	Diguanylate cyclase
GPX85_RS01625	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GPX85_RS01630	ENOG4107SEY	Conserved Protein
GPX85_RS01635	ENOG4108XDN	Transcriptional regulator
GPX85_RS01640	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GPX85_RS01650	ENOG4105D6U	Sodium Glutamate Symporter
GPX85_RS01655	ENOG4105D6U	Sodium Glutamate Symporter
GPX85_RS01665	ENOG4105DN9	Na H antiporter
GPX85_RS01670	ENOG4105VYW	UPF0251 protein
GPX85_RS01685	ENOG4107RH7	Nicotinate phosphoribosyltransferase
GPX85_RS01690	ENOG4105D9R	oxidoreductase
GPX85_RS01695	ENOG4105D17	glycoside hydrolase, family 3 domain protein
GPX85_RS01700	ENOG4105EHZ	conserved protein UCP016719
GPX85_RS01705	ENOG4105BZU	Histidine kinase
GPX85_RS01745	ENOG4105UYK	outer membrane protein a
GPX85_RS01750	ENOG4108WQH	regulatoR
GPX85_RS01755	ENOG4105BZU	Histidine kinase
GPX85_RS01760	ENOG4105D82	Glutamate dehydrogenase
GPX85_RS01770	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
GPX85_RS01790	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GPX85_RS01795	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
GPX85_RS01800	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GPX85_RS01805	ENOG4105DHT	Metal Dependent Phosphohydrolase
GPX85_RS01820	ENOG4105EXG	Transcriptional regulator
GPX85_RS01830	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GPX85_RS01835	ENOG4105KUU	lipolytic protein G-D-S-L family
GPX85_RS01840	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GPX85_RS01845	ENOG4105CPQ	Dehydrogenase
GPX85_RS01865	ENOG4105CMT	Dihydroxyacetone kinase
GPX85_RS01870	ENOG4108UTZ	Dihydroxyacetone kinase
GPX85_RS01885	ENOG4108HK0	-acetyltransferase
GPX85_RS01890	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GPX85_RS01900	ENOG4108IJ9	(ABC) transporter
GPX85_RS01905	ENOG4107FKK	extracellular solute-binding protein family 1
GPX85_RS01910	ENOG4105D56	permease protein
GPX85_RS01915	ENOG4105EG2	ABC transporter, permease
GPX85_RS01940	ENOG4105NNS	Autoinducer synthesis protein
GPX85_RS01945	ENOG4105VJY	transcriptional regulator
GPX85_RS01950	ENOG4105E98	transcriptional regulator DeoR family
GPX85_RS01970	ENOG4105EKE	dihydroorotase
GPX85_RS01975	ENOG4105QVC	MOSC domain-containing protein
GPX85_RS02005	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GPX85_RS02010	ENOG4105EHG	Permease protein
GPX85_RS02015	ENOG4107R4I	Periplasmic binding protein
GPX85_RS02020	ENOG41090JE	Utilization Protein
GPX85_RS02025	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
GPX85_RS02040	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GPX85_RS02045	ENOG4105CYW	agmatinase
GPX85_RS02050	ENOG4105DZ1	carboxypeptidase
GPX85_RS02070	ENOG4105C94	Transporter
GPX85_RS02085	ENOG4108ISG	Major Facilitator
GPX85_RS02090	ENOG4105K63	Thioredoxin
GPX85_RS02095	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GPX85_RS02100	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GPX85_RS02105	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
GPX85_RS02110	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
GPX85_RS02115	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GPX85_RS02145	ENOG41082IR	Excinuclease ABC C subunit domain protein
GPX85_RS02150	ENOG4108QGH	periplasmic
GPX85_RS02155	ENOG4105BZU	Histidine kinase
GPX85_RS02165	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GPX85_RS02170	ENOG4105E0C	molybdate abc transporter
GPX85_RS02175	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GPX85_RS02190	ENOG4105EM2	membrane
GPX85_RS02195	ENOG41088T4	Helicase IV
GPX85_RS02200	ENOG4108RWI	nicotinamidase
GPX85_RS02205	ENOG4108Z5K	methylglyoxal synthase
GPX85_RS02210	ENOG4105EWV	Sodium calcium exchanger membrane region
GPX85_RS02220	ENOG4108I6A	alcohol dehydrogenase
GPX85_RS02225	ENOG4105CF7	AraC family transcriptional regulator
GPX85_RS02235	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GPX85_RS02240	ENOG4105BZU	Histidine kinase
GPX85_RS02255	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPX85_RS02260	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPX85_RS02265	ENOG4108JUA	Transcriptional regulator
GPX85_RS02280	ENOG4105C28	cystathionine
GPX85_RS02285	ENOG4105VNT	transposase (IS4 family) protein
GPX85_RS02290	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS02315	ENOG4105CEE	C4-dicarboxylate transporter
GPX85_RS02325	ENOG4107VXZ	Hydrolase
GPX85_RS02330	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GPX85_RS02340	ENOG4105CDV	Ompa motb domain protein
GPX85_RS02345	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GPX85_RS02355	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GPX85_RS02370	ENOG4105KHC	sulfurtransferase
GPX85_RS02375	ENOG4105D06	uba thif-type nad fad binding protein
GPX85_RS02380	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GPX85_RS02390	ENOG4105E0X	reductase
GPX85_RS02395	ENOG4105CKU	formyltetrahydrofolate synthetase
GPX85_RS02400	ENOG4105VEQ	Cold shock protein
GPX85_RS02410	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPX85_RS02415	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GPX85_RS02425	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GPX85_RS02435	ENOG4105BZU	Histidine kinase
GPX85_RS02440	ENOG4107RE1	Inosine-guanosine kinase
GPX85_RS02455	ENOG4107XGZ	Hydrolase
GPX85_RS02465	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GPX85_RS02475	ENOG4105RKW	reductase (By
GPX85_RS02485	ENOG4108I0Y	(ABC) transporter
GPX85_RS02490	ENOG4105CV6	ABC transporter, permease
GPX85_RS02500	ENOG4105E7W	lamb ycsf family protein
GPX85_RS02505	ENOG4105CMR	udp-glucose 4-epimerase
GPX85_RS02515	ENOG4105E0U	tyrosine-specific transport protein
GPX85_RS02520	ENOG4105C1J	atp-dependent rna helicase
GPX85_RS02540	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
GPX85_RS02570	ENOG4105RA2	Membrane
GPX85_RS02590	ENOG4108JU3	Alkyl hydroperoxide reductase
GPX85_RS02595	ENOG4105D3R	alkyl hydroperoxide reductase
GPX85_RS02620	ENOG41080HT	Transcriptional regulator, arsr family
GPX85_RS02645	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
GPX85_RS02650	ENOG4105CGF	Aromatic amino acid aminotransferase
GPX85_RS02655	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPX85_RS02660	ENOG4105DM4	PTS System
GPX85_RS02665	ENOG4105DE4	1-phosphofructokinase
GPX85_RS02670	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
GPX85_RS02675	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
GPX85_RS02680	ENOG4107RFY	SbcCD D subunit
GPX85_RS02685	ENOG4105EYH	Exonuclease
GPX85_RS02690	ENOG4108MGY	Histidine kinase
GPX85_RS02695	ENOG4107KBT	8-Amino-7-oxononanoate synthase
GPX85_RS02700	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
GPX85_RS02705	ENOG4105PAD	Hydrolase
GPX85_RS02710	ENOG4105NXH	GreA GreB family elongation factor
GPX85_RS02715	ENOG4108K85	Transcriptional regulator
GPX85_RS02740	ENOG4105YB8	TM2 domain containing protein
GPX85_RS02755	ENOG4105BZU	Histidine kinase
GPX85_RS02770	ENOG4105CMQ	Chloride channel
GPX85_RS02775	ENOG4105CKI	cobalamin synthesis protein
GPX85_RS02780	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GPX85_RS02785	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GPX85_RS02790	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GPX85_RS02805	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
GPX85_RS02815	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
GPX85_RS02825	ENOG4105C6Z	Gluconate
GPX85_RS02830	ENOG4105EXW	epimerase dehydratase
GPX85_RS02835	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
GPX85_RS02840	ENOG4105FB2	class II Aldolase
GPX85_RS02845	ENOG4105G63	Type III effector Hrp-dependent
GPX85_RS02850	ENOG4105ZXK	Dehydrogenase
GPX85_RS02855	ENOG4105MVE	transcriptional regulator
GPX85_RS02875	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GPX85_RS02880	ENOG4106YYS	transcriptional regulatory protein
GPX85_RS02885	ENOG4105C5H	ABC transporter
GPX85_RS02890	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GPX85_RS02895	ENOG4105G0K	glycine radical enzyme YjjI family
GPX85_RS02900	ENOG41076CZ	activating enzyme
GPX85_RS02910	ENOG4105E0K	tonB-dependent siderophore receptor
GPX85_RS02925	ENOG41080XP	Cbs domain
GPX85_RS02935	ENOG4105DS1	cytochrome b561
GPX85_RS02940	ENOG4108YYC	ycei family
GPX85_RS02945	ENOG4105TMB	Formate nitrite transporter
GPX85_RS02950	ENOG4105DUM	transcriptional regulator, lysR family
GPX85_RS02955	ENOG4108UQ5	membrane protein YcdZ
GPX85_RS02960	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
GPX85_RS02965	ENOG4105CGH	5'-nucleotidase
GPX85_RS02970	ENOG4105DU1	integral membrane protein, terc
GPX85_RS02980	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
GPX85_RS02990	ENOG4105KA0	thioesterase Superfamily protein
GPX85_RS03005	ENOG4105CWB	LysR family transcriptional Regulator
GPX85_RS03010	ENOG4105CD5	CoA-binding domain protein
GPX85_RS03020	ENOG4105CPF	Cell wall formation (By similarity)
GPX85_RS03035	ENOG4108ZJT	translation initiation factor, Sui1
GPX85_RS03100	ENOG4108IQK	o-acetylhomoserine
GPX85_RS03125	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
GPX85_RS03135	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GPX85_RS03140	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GPX85_RS03155	ENOG4106TD9	Diguanylate cyclase
GPX85_RS03160	ENOG4105BZU	Histidine kinase
GPX85_RS03165	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GPX85_RS03195	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
GPX85_RS03200	ENOG41080ET	plasmid maintenance system killer protein
GPX85_RS03210	ENOG4105EKQ	RNA-directed DNA polymerase
GPX85_RS03225	ENOG4105EKQ	RNA-directed DNA polymerase
GPX85_RS03330	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GPX85_RS03380	ENOG4105EKQ	RNA-directed DNA polymerase
GPX85_RS03450	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GPX85_RS03465	ENOG4105EKQ	RNA-directed DNA polymerase
GPX85_RS03500	ENOG4105EKQ	RNA-directed DNA polymerase
GPX85_RS03635	ENOG4105EKQ	RNA-directed DNA polymerase
GPX85_RS03760	ENOG4105VXN	addiction module toxin, RelE StbE family
GPX85_RS03800	ENOG4105D9U	N-acetyltransferase
GPX85_RS03820	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GPX85_RS03900	ENOG4105DBV	ornithine carbamoyltransferase
GPX85_RS03905	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GPX85_RS03910	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GPX85_RS03925	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
GPX85_RS03935	ENOG4107QN1	sodium solute
GPX85_RS03945	ENOG4105EX9	Membrane
GPX85_RS03950	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GPX85_RS03955	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GPX85_RS03960	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GPX85_RS03965	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
GPX85_RS03970	ENOG4105CB5	ATP-dependent DNA helicase recG
GPX85_RS03975	ENOG4105C2W	permease
GPX85_RS03980	ENOG4105E0F	Histidine kinase
GPX85_RS03985	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GPX85_RS03995	ENOG4105C6Z	Gluconate
GPX85_RS04000	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GPX85_RS04005	ENOG4105C01	Dihydroxy-acid dehydratase
GPX85_RS04010	ENOG4105DIQ	Transcriptional regulator
GPX85_RS04015	ENOG4108RRZ	Transcription elongation factor GreB
GPX85_RS04020	ENOG4105BZM	domain protein
GPX85_RS04030	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GPX85_RS04035	ENOG4105MJ2	Competence protein
GPX85_RS04040	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
GPX85_RS04045	ENOG4107RK2	ADP-ribose diphosphatase NudE
GPX85_RS04050	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GPX85_RS04055	ENOG4105PIC	general secretion pathway protein N
GPX85_RS04060	ENOG4105U1E	general secretion pathway protein M
GPX85_RS04065	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
GPX85_RS04070	ENOG4108RTD	type II secretion system protein K
GPX85_RS04075	ENOG4108WWZ	General secretion pathway protein J
GPX85_RS04080	ENOG4105X5Z	General secretion pathway protein I
GPX85_RS04085	ENOG4105VWV	general secretion pathway protein h
GPX85_RS04090	ENOG4108VAU	general secretion pathway protein G
GPX85_RS04095	ENOG4105D7Q	type ii secretion system
GPX85_RS04100	ENOG4107QHF	type ii secretion system protein e
GPX85_RS04110	ENOG4108XKW	General secretion pathway protein C
GPX85_RS04115	ENOG4105VEJ	Heat shock protein
GPX85_RS04120	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GPX85_RS04125	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GPX85_RS04135	ENOG4105SUU	thioesterase domain
GPX85_RS04140	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GPX85_RS04145	ENOG4107S2Z	UPF0761 membrane protein
GPX85_RS04150	ENOG4105CI3	gtp-binding protein typa
GPX85_RS04155	ENOG4105C5F	glutamine synthetase
GPX85_RS04165	ENOG4105CUX	Signal transduction histidine kinase
GPX85_RS04170	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPX85_RS04175	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GPX85_RS04245	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
GPX85_RS04270	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GPX85_RS04290	ENOG4108YGG	dna repair protein
GPX85_RS04315	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS04370	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
GPX85_RS04375	ENOG4107R73	Mate efflux family protein
GPX85_RS04385	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GPX85_RS04390	ENOG4105E55	glycerol-3-phosphate acyltransferase
GPX85_RS04395	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GPX85_RS04415	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GPX85_RS04420	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPX85_RS04425	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GPX85_RS04430	ENOG4105CAK	Cell division ATP-binding protein ftsE
GPX85_RS04435	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GPX85_RS04440	ENOG4106H78	methyltransferase
GPX85_RS04445	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
GPX85_RS04470	ENOG4108RMU	ferritin dps family protein
GPX85_RS04475	ENOG4108EUD	Lysophospholipase
GPX85_RS04480	ENOG4105DQF	Hydrolase
GPX85_RS04495	ENOG4106IUH	DTW domain containing protein
GPX85_RS04500	ENOG4105BZU	Histidine kinase
GPX85_RS04505	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
GPX85_RS04510	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GPX85_RS04515	ENOG4105CT0	Protein of unknown function, DUF484
GPX85_RS04520	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GPX85_RS04525	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GPX85_RS04535	ENOG4107T0K	Adenylate cyclase
GPX85_RS04545	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GPX85_RS04550	ENOG41076E6	Uroporphyrinogen-III Synthase
GPX85_RS04555	ENOG4105ECF	c-methyltransferase
GPX85_RS04565	ENOG4105D4P	Coproporphyrinogen iii oxidase
GPX85_RS04570	ENOG4105XCT	Protein of unknown function (DUF2489)
GPX85_RS04585	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GPX85_RS04590	ENOG4105C2M	dna polymerase I
GPX85_RS04595	ENOG4105D52	delta-aminolevulinic acid dehydratase
GPX85_RS04600	ENOG4105F8V	Hydrolase, tatD family
GPX85_RS04605	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GPX85_RS04610	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GPX85_RS04615	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GPX85_RS04620	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GPX85_RS04625	ENOG4105JC1	sterol-binding domain protein
GPX85_RS04630	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GPX85_RS04635	ENOG4105CGY	Dna recombination protein
GPX85_RS04660	ENOG4105CBX	hi0933 family
GPX85_RS04665	ENOG4108V6B	universal stress protein B
GPX85_RS04670	ENOG41090A1	ferritin
GPX85_RS04675	ENOG4108M6U	Universal stress protein A
GPX85_RS04680	ENOG4105EMK	carboxylate amino acid amine transporter
GPX85_RS04690	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
GPX85_RS04695	ENOG4108VVK	transcriptional Regulator, AsnC
GPX85_RS04715	ENOG4105DC7	peptidase M24
GPX85_RS04715	ENOG4105DC7	peptidase M24
GPX85_RS04720	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
GPX85_RS04725	ENOG4105C26	Dehydrogenase
GPX85_RS04730	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
GPX85_RS04745	ENOG4108IJ7	Glycine betaine
GPX85_RS04750	ENOG4105D41	biosynthesis protein thiH
GPX85_RS04755	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GPX85_RS04765	ENOG4105D06	uba thif-type nad fad binding protein
GPX85_RS04780	ENOG4107R4J	Chloride channel
GPX85_RS04840	ENOG4108RR8	protoporphyrinogen oxidase
GPX85_RS04845	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GPX85_RS04850	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GPX85_RS04855	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GPX85_RS04860	ENOG4105CHU	acetyl-coa acetyltransferase
GPX85_RS04865	ENOG4105F52	Transcriptional regulator
GPX85_RS04875	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GPX85_RS04880	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GPX85_RS04885	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GPX85_RS04890	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GPX85_RS04895	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GPX85_RS04905	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GPX85_RS04910	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GPX85_RS04915	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GPX85_RS04925	ENOG4105FA0	parb-like partition protein
GPX85_RS04930	ENOG4107QJE	Chromosome Partitioning Protein
GPX85_RS04935	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GPX85_RS04940	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GPX85_RS04945	ENOG4108ZNX	Heat shock protein
GPX85_RS04950	ENOG4108RS6	transposase
GPX85_RS04965	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPX85_RS04970	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GPX85_RS04975	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GPX85_RS04980	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GPX85_RS04990	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GPX85_RS04995	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GPX85_RS05000	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPX85_RS05005	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GPX85_RS05015	ENOG4105BZU	Histidine kinase
GPX85_RS05025	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GPX85_RS05030	ENOG4105QTB	Flavodoxin
GPX85_RS05040	ENOG4108RPN	Protein smg homolog
GPX85_RS05045	ENOG4105C79	DNA protecting protein DprA
GPX85_RS05065	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GPX85_RS05070	ENOG4105C1A	potassium transporter peripheral membrane
GPX85_RS05075	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GPX85_RS05080	ENOG4108UT2	hemolysin iii
GPX85_RS05090	ENOG4105PC1	Conserved Protein
GPX85_RS05095	ENOG4105E27	serine threonine protein kinase
GPX85_RS05100	ENOG4108Z33	Thiol disulfide Interchange Protein
GPX85_RS05105	ENOG4105C0P	Mg chelatase subunit ChlI
GPX85_RS05115	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
GPX85_RS05120	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GPX85_RS05125	ENOG4105C01	Dihydroxy-acid dehydratase
GPX85_RS05130	ENOG4105C7B	Threonine dehydratase
GPX85_RS05135	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
GPX85_RS05140	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GPX85_RS05155	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
GPX85_RS05160	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GPX85_RS05165	ENOG4105JKW	Valine--pyruvate aminotransferase
GPX85_RS05170	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GPX85_RS05175	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GPX85_RS05180	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GPX85_RS05190	ENOG4105E2X	shikimate dehydrogenase
GPX85_RS05195	ENOG4105SG3	Protein of unknown function (DUF1488)
GPX85_RS05200	ENOG4108Z0R	Transferase
GPX85_RS05235	ENOG4105EMY	transcriptional regulator
GPX85_RS05240	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GPX85_RS05245	ENOG4105W0Z	cytoplasmic protein
GPX85_RS05250	ENOG4108RS6	transposase
GPX85_RS05255	ENOG4105BZS	acriflavin resistance protein
GPX85_RS05260	ENOG410624X	efflux transporter, rnd family, mfp subunit
GPX85_RS05265	ENOG4105C4R	Atp-dependent dna helicase
GPX85_RS05295	ENOG4108JQ6	ABC transporter
GPX85_RS05300	ENOG4105DEF	Extracellular solute-binding protein, family 5
GPX85_RS05305	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GPX85_RS05310	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPX85_RS05325	ENOG4105DC8	reductase
GPX85_RS05330	ENOG4105D6S	protein involved in catabolism of external DNA
GPX85_RS05335	ENOG4105DGW	oligopeptidase A
GPX85_RS05340	ENOG4105C4R	Atp-dependent dna helicase
GPX85_RS05345	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
GPX85_RS05350	ENOG4105FR1	rard protein
GPX85_RS05355	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GPX85_RS05365	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
GPX85_RS05370	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPX85_RS05375	ENOG4105C5Y	PTS System
GPX85_RS05390	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GPX85_RS05415	ENOG4105CT4	transporter
GPX85_RS05420	ENOG4105CT4	transporter
GPX85_RS05425	ENOG4105CJQ	hydrolase, family 31
GPX85_RS05435	ENOG4105ETE	Transcriptional regulator (LacI family
GPX85_RS05440	ENOG4105CI2	imidazolone-5-propionate hydrolase
GPX85_RS05445	ENOG4107RAN	Peptidase, M16
GPX85_RS05450	ENOG4107QHE	Choloylglycine hydrolase
GPX85_RS05460	ENOG4105J12	Multidrug resistance protein mdtN
GPX85_RS05465	ENOG4108MI0	Resistance protein
GPX85_RS05490	ENOG4105K5B	UPF0225 protein
GPX85_RS05500	ENOG4105DSJ	YicC domain protein
GPX85_RS05505	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GPX85_RS05510	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GPX85_RS05515	ENOG4105FCD	Major Facilitator
GPX85_RS05520	ENOG4105DY9	regulatoR
GPX85_RS05525	ENOG4108HRK	Histidine kinase
GPX85_RS05530	ENOG4105D1S	lipid A biosynthesis
GPX85_RS05535	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GPX85_RS05540	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GPX85_RS05550	ENOG4105KDC	50s ribosomal protein l28
GPX85_RS05555	ENOG4105W0E	50S ribosomal protein L33
GPX85_RS05565	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GPX85_RS05570	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GPX85_RS05575	ENOG4105M5K	heptosyltransferase
GPX85_RS05580	ENOG4106WTF	Glycosyl transferase, family 2
GPX85_RS05590	ENOG4105DKP	glycosyl transferase, family 9
GPX85_RS05595	ENOG41080IJ	Diacylglycerol kinase
GPX85_RS05605	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GPX85_RS05610	ENOG4105XA0	heptosyltransferase ii
GPX85_RS05630	ENOG4105CG5	Glycosyl transferase (Group 1
GPX85_RS05645	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
GPX85_RS05665	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GPX85_RS05675	ENOG4105E3R	(LipO)protein
GPX85_RS05710	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GPX85_RS05715	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
GPX85_RS05735	ENOG4108UW5	maltose o-acetyltransferase
GPX85_RS05740	ENOG4105EGZ	biosynthesis protein
GPX85_RS05770	ENOG410600T	transposase
GPX85_RS05780	ENOG4105DMT	epimerase dehydratase
GPX85_RS05785	ENOG4105CY0	Metallo-Beta-Lactamase
GPX85_RS05795	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GPX85_RS05800	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
GPX85_RS05810	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
GPX85_RS05815	ENOG4105ESV	Glycosyl transferase, family 4
GPX85_RS05825	ENOG4107V1M	polysaccharide export protein
GPX85_RS05840	ENOG4105ECX	polysaccharide export
GPX85_RS05845	ENOG4105E12	capsule polysaccharide
GPX85_RS05865	ENOG4107QQG	Dehydrogenase
GPX85_RS05870	ENOG4105K64	Glycosyl transferase, family 2
GPX85_RS05890	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GPX85_RS05895	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GPX85_RS05900	ENOG4105K64	Glycosyl transferase, family 2
GPX85_RS05915	ENOG4105K64	Glycosyl transferase, family 2
GPX85_RS05955	ENOG4105CXY	transporter
GPX85_RS05960	ENOG4105BZU	Histidine kinase
GPX85_RS05965	ENOG4108KX4	response regulator
GPX85_RS05970	ENOG4105CXY	transporter
GPX85_RS05975	ENOG4108KX4	response regulator
GPX85_RS05980	ENOG4105BZU	Histidine kinase
GPX85_RS05985	ENOG4105CXY	transporter
GPX85_RS05990	ENOG4105C4Y	ABC transporter
GPX85_RS06000	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPX85_RS06005	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS06010	ENOG4105R2J	Conserved Protein
GPX85_RS06015	ENOG4105CUY	Mechanosensitive ion channel
GPX85_RS06025	ENOG4105K70	DNA-binding protein
GPX85_RS06035	ENOG4105C12	Phosphoribosylglycinamide synthetase
GPX85_RS06040	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GPX85_RS06055	ENOG4108M3R	transcriptional activator CadC
GPX85_RS06060	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
GPX85_RS06065	ENOG4105D5Q	Arginine ornithine antiporter
GPX85_RS06070	ENOG4105CXN	decarboxylase
GPX85_RS06075	ENOG4105EIP	mannose-6-phosphate isomerase
GPX85_RS06080	ENOG4105DM4	PTS System
GPX85_RS06085	ENOG4108CIP	transcriptional regulator
GPX85_RS06095	ENOG4108YRF	PTS System
GPX85_RS06105	ENOG4107R11	Transcriptional regulator
GPX85_RS06110	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
GPX85_RS06115	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GPX85_RS06120	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GPX85_RS06125	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GPX85_RS06130	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GPX85_RS06135	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GPX85_RS06155	ENOG4105D8G	Major Facilitator superfamily
GPX85_RS06160	ENOG4105BZU	Histidine kinase
GPX85_RS06165	ENOG4105C9X	ppx gppa phosphatase
GPX85_RS06170	ENOG4105C1J	atp-dependent rna helicase
GPX85_RS06175	ENOG4105K63	Thioredoxin
GPX85_RS06180	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GPX85_RS06185	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GPX85_RS06190	ENOG4107QK7	reductase
GPX85_RS06230	ENOG4105JIM	Phosphatidylserine synthase
GPX85_RS06240	ENOG4105D4A	Cell wall formation (By similarity)
GPX85_RS06245	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GPX85_RS06250	ENOG4105CS9	pantothenic acid kinase
GPX85_RS06280	ENOG4105PM1	preprotein translocase subunit SecE
GPX85_RS06285	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GPX85_RS06295	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GPX85_RS06300	ENOG4108VZM	50s ribosomal protein L10
GPX85_RS06305	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GPX85_RS06310	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GPX85_RS06315	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GPX85_RS06320	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
GPX85_RS06325	ENOG4105E09	nadh pyrophosphatase
GPX85_RS06330	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GPX85_RS06335	ENOG41062JF	Transcriptional regulator
GPX85_RS06345	ENOG41063SB	peptidase
GPX85_RS06350	ENOG4105C1J	atp-dependent rna helicase
GPX85_RS06355	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GPX85_RS06360	ENOG4105C8P	)-transporter
GPX85_RS06370	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GPX85_RS06375	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GPX85_RS06425	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GPX85_RS06430	ENOG4105K8N	protein family UPF0079, ATPase
GPX85_RS06435	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GPX85_RS06440	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GPX85_RS06445	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GPX85_RS06450	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GPX85_RS06455	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GPX85_RS06460	ENOG4107QJR	hflk protein
GPX85_RS06465	ENOG4105EPW	hflc protein
GPX85_RS06475	ENOG41069P5	Protein slyX homolog
GPX85_RS06485	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GPX85_RS06490	ENOG4105WWK	YheO domain protein
GPX85_RS06495	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
GPX85_RS06500	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GPX85_RS06505	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GPX85_RS06510	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GPX85_RS06515	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GPX85_RS06530	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GPX85_RS06535	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GPX85_RS06540	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GPX85_RS06550	ENOG4105CDU	Replicative dna helicase
GPX85_RS06560	ENOG4107QP8	phosphohexose isomerase
GPX85_RS06570	ENOG4105MYN	Zinc uptake regulation protein
GPX85_RS06575	ENOG4105CFC	Transporter
GPX85_RS06580	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GPX85_RS06595	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GPX85_RS06600	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GPX85_RS06605	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GPX85_RS06640	ENOG4105EEQ	Na H antiporter
GPX85_RS06645	ENOG4105C3R	Methionine synthase
GPX85_RS06650	ENOG4105CFH	Aspartokinase
GPX85_RS06655	ENOG4105C5R	Aminotransferase
GPX85_RS06665	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GPX85_RS06670	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GPX85_RS06675	ENOG41086KC	Transcriptional regulator
GPX85_RS06680	ENOG4108UUM	single-stranded DNA-binding protein
GPX85_RS06685	ENOG41062P1	Diguanylate cyclase phosphodiesterase
GPX85_RS06720	ENOG4107QHF	type ii secretion system protein e
GPX85_RS06725	ENOG4105D7Q	type ii secretion system
GPX85_RS06735	ENOG4105X0D	Fimbrial protein
GPX85_RS06765	ENOG4105DFF	Rod shape-determining protein mreb
GPX85_RS06770	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GPX85_RS06775	ENOG4105VQ7	Rod shape-determining protein MreD
GPX85_RS06780	ENOG4108Z03	MAF-like protein
GPX85_RS06785	ENOG4105C03	ribonuclease
GPX85_RS06790	ENOG4105QD6	exported protein
GPX85_RS06800	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GPX85_RS06820	ENOG4105SHT	UspA domain-containing protein
GPX85_RS06835	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GPX85_RS06845	ENOG4105D5Q	Arginine ornithine antiporter
GPX85_RS06850	ENOG4105EAH	synthase
GPX85_RS06855	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GPX85_RS06860	ENOG4105K46	50S ribosomal protein l27
GPX85_RS06865	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPX85_RS06870	ENOG4105DWK	Membrane
GPX85_RS06885	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GPX85_RS06890	ENOG4105NWN	ApaG protein
GPX85_RS06895	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GPX85_RS06900	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GPX85_RS06905	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GPX85_RS06910	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GPX85_RS06915	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GPX85_RS06965	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
GPX85_RS06970	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GPX85_RS06975	ENOG4105CEN	a g-specific adenine glycosylase
GPX85_RS06980	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GPX85_RS06985	ENOG4105CSV	Glutaminase
GPX85_RS06990	ENOG4105CSA	Coproporphyrinogen iii oxidase
GPX85_RS06995	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GPX85_RS07000	ENOG4105VZ9	UPF0235 protein
GPX85_RS07005	ENOG4108VIA	integral membrane protein
GPX85_RS07010	ENOG4105II7	pyrroline-5-carboxylate reductase
GPX85_RS07015	ENOG4105DFA	alanine racemase domain protein
GPX85_RS07020	ENOG4105CZX	twitching motility protein
GPX85_RS07025	ENOG4105CZX	twitching motility protein
GPX85_RS07030	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GPX85_RS07035	ENOG4108UJU	UPF0301 protein
GPX85_RS07040	ENOG4105D7Z	glutathione synthase
GPX85_RS07045	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GPX85_RS07050	ENOG4105RWS	endonuclease I
GPX85_RS07055	ENOG4105GPY	SprT protein
GPX85_RS07060	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GPX85_RS07070	ENOG4108R4R	Iron-regulated virulence regulatory protein
GPX85_RS07075	ENOG4105D05	Receptor
GPX85_RS07080	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GPX85_RS07085	ENOG4105BZA	Phosphoglycerate kinase
GPX85_RS07090	ENOG4105D2N	Aldolase
GPX85_RS07095	ENOG4105D64	Mechanosensitive ion channel
GPX85_RS07105	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
GPX85_RS07115	ENOG4105BZU	Histidine kinase
GPX85_RS07120	ENOG4105CA9	Pyruvate kinase
GPX85_RS07125	ENOG410804X	Transcriptional regulator
GPX85_RS07130	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GPX85_RS07155	ENOG4105EKQ	RNA-directed DNA polymerase
GPX85_RS07160	ENOG4105DIJ	Phosphoethanolamine transferase
GPX85_RS07165	ENOG41080IJ	Diacylglycerol kinase
GPX85_RS07175	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GPX85_RS07180	ENOG4105BZU	Histidine kinase
GPX85_RS07225	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
GPX85_RS07230	ENOG4105N1P	Ferredoxin-type protein
GPX85_RS07240	ENOG4105QAX	Iron-sulfur
GPX85_RS07245	ENOG4107KGK	dmso reductase anchor subunit
GPX85_RS07250	ENOG4108NEM	leader-binding protein dmsD
GPX85_RS07255	ENOG4105C94	Transporter
GPX85_RS07280	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPX85_RS07285	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GPX85_RS07290	ENOG4105KTH	gatB Yqey
GPX85_RS07295	ENOG4105VCC	30S ribosomal protein S21
GPX85_RS07300	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GPX85_RS07305	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GPX85_RS07310	ENOG4107ZVW	dihydroneopterin aldolase
GPX85_RS07315	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPX85_RS07320	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GPX85_RS07325	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GPX85_RS07330	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GPX85_RS07335	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GPX85_RS07345	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GPX85_RS07350	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GPX85_RS07355	ENOG4108K5P	(LipO)protein
GPX85_RS07360	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPX85_RS07365	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GPX85_RS07370	ENOG4105C6T	cysteine synthase
GPX85_RS07375	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
GPX85_RS07380	ENOG4108I5D	sulfate abc transporter
GPX85_RS07385	ENOG4105ECW	sulfate abc transporter
GPX85_RS07390	ENOG4108IJ6	ABC transporter
GPX85_RS07395	ENOG4107TH8	cina domain protein
GPX85_RS07400	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GPX85_RS07405	ENOG4105Y3E	Modulates RecA activity (By similarity)
GPX85_RS07415	ENOG4105CFH	Aspartokinase
GPX85_RS07420	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GPX85_RS07470	ENOG4107QSA	Oxaloacetate decarboxylase
GPX85_RS07475	ENOG4105D9Q	decarboxylase (Beta subunit)
GPX85_RS07480	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
GPX85_RS07485	ENOG4105W39	Membrane
GPX85_RS07495	ENOG4105D9M	gamma-glutamylcysteine synthetase
GPX85_RS07500	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GPX85_RS07505	ENOG4108JU6	CBS domain protein
GPX85_RS07510	ENOG4106KVJ	cytochrome C assembly protein
GPX85_RS07515	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPX85_RS07520	ENOG4105K5M	30s ribosomal protein S16
GPX85_RS07525	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GPX85_RS07530	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GPX85_RS07535	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GPX85_RS07545	ENOG4105C0H	protease
GPX85_RS07555	ENOG4105D6Z	AFG1 family ATPase
GPX85_RS07560	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GPX85_RS07565	ENOG4108UJD	30S ribosomal protein S9
GPX85_RS07570	ENOG4107MKT	Stringent starvation protein a
GPX85_RS07575	ENOG4105KB2	stringent starvation protein b
GPX85_RS07580	ENOG4105W4M	Transport-associated protein
GPX85_RS07585	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GPX85_RS07590	ENOG41082RQ	UPF0102 protein
GPX85_RS07595	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
GPX85_RS07600	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GPX85_RS07610	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GPX85_RS07615	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GPX85_RS07620	ENOG4105CJN	penicillin-binding protein
GPX85_RS07625	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GPX85_RS07630	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GPX85_RS07635	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GPX85_RS07640	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GPX85_RS07650	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GPX85_RS07655	ENOG4105DFU	Cell wall formation (By similarity)
GPX85_RS07660	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GPX85_RS07665	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GPX85_RS07670	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GPX85_RS07675	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPX85_RS07685	ENOG4105M6F	mutator MutT protein
GPX85_RS07690	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GPX85_RS07700	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GPX85_RS07705	ENOG4105EJ9	Membrane
GPX85_RS07710	ENOG4105VP0	transcriptional regulator, lysR family
GPX85_RS07715	ENOG4105EN6	Membrane
GPX85_RS07730	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GPX85_RS07750	ENOG4105N5T	Radical SAM Protein
GPX85_RS07755	ENOG4105BZU	Histidine kinase
GPX85_RS07765	ENOG41065U4	response regulator
GPX85_RS07775	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GPX85_RS07790	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GPX85_RS07795	ENOG4105D98	threonine synthase
GPX85_RS07800	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
GPX85_RS07805	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GPX85_RS07810	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GPX85_RS07840	ENOG4105EYA	deoxyribonuclease
GPX85_RS07845	ENOG4105D9N	nucleoside
GPX85_RS07850	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GPX85_RS07855	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GPX85_RS07860	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GPX85_RS07865	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GPX85_RS07875	ENOG4105EAC	phosphoserine phosphatase
GPX85_RS07885	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GPX85_RS07900	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GPX85_RS07905	ENOG4105CAH	Chromate
GPX85_RS07920	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPX85_RS07930	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
GPX85_RS07935	ENOG4105X2V	dna damage-inducible protein
GPX85_RS07940	ENOG4105DUM	transcriptional regulator, lysR family
GPX85_RS07950	ENOG4105DSY	exodeoxyribonuclease V, gamma
GPX85_RS07960	ENOG4107QYX	exodeoxyribonuclease v alpha
GPX85_RS07965	ENOG4107QZM	n-acetylglutamate synthase
GPX85_RS07975	ENOG4105CA3	membrane-bound lytic murein transglycosylase
GPX85_RS07980	ENOG4105CUZ	uba thif-type nad fad binding protein
GPX85_RS07985	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GPX85_RS07990	ENOG4107S0N	DJ-1 family
GPX85_RS07995	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GPX85_RS08000	ENOG4105CGH	5'-nucleotidase
GPX85_RS08005	ENOG4105DRB	nucleoside-specific channel-forming protein
GPX85_RS08015	ENOG4105K6V	RNA polymerase
GPX85_RS08035	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GPX85_RS08040	ENOG4105CFP	Peptidase U32
GPX85_RS08045	ENOG4105DH7	May be involved in recombination (By similarity)
GPX85_RS08050	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GPX85_RS08055	ENOG4105BZU	Histidine kinase
GPX85_RS08065	ENOG4105C9X	ppx gppa phosphatase
GPX85_RS08070	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GPX85_RS08075	ENOG4105C8U	phosphate abc transporter
GPX85_RS08080	ENOG4105E2Z	phosphate ABC transporter (Permease
GPX85_RS08085	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GPX85_RS08095	ENOG4106N3A	copper homeostasis protein cutc
GPX85_RS08100	ENOG4105D3R	alkyl hydroperoxide reductase
GPX85_RS08105	ENOG4105C5Q	Transcriptional regulator
GPX85_RS08110	ENOG4107QP3	malate synthase g
GPX85_RS08115	ENOG4108I9X	Isocitrate lyase
GPX85_RS08120	ENOG4105W87	Cbs domain
GPX85_RS08125	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GPX85_RS08130	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GPX85_RS08135	ENOG4105VIE	preprotein translocase, subunit YajC
GPX85_RS08140	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPX85_RS08145	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPX85_RS08150	ENOG4105ECY	inositol monophosphatase
GPX85_RS08155	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
GPX85_RS08160	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GPX85_RS08165	ENOG4105C3J	Cysteine desulfurase
GPX85_RS08170	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GPX85_RS08175	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GPX85_RS08185	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
GPX85_RS08190	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GPX85_RS08195	ENOG4105CUT	histidyl-tRNA synthetase
GPX85_RS08200	ENOG4105N21	Membrane
GPX85_RS08205	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GPX85_RS08210	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GPX85_RS08220	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GPX85_RS08225	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GPX85_RS08230	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GPX85_RS08235	ENOG4108KSA	LysR family transcriptional regulator
GPX85_RS08240	ENOG4105CPC	Aldo Keto reductase
GPX85_RS08255	ENOG4105C94	Transporter
GPX85_RS08260	ENOG4106HK8	GPR1 FUN34 yaaH family protein
GPX85_RS08265	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
GPX85_RS08275	ENOG4108P2H	Inner membrane protein YjiG
GPX85_RS08280	ENOG41074DU	domain protein
GPX85_RS08290	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GPX85_RS08310	ENOG4105CJW	magnesium transporter
GPX85_RS08320	ENOG4105CJW	magnesium transporter
GPX85_RS08345	ENOG4107UNZ	domain protein
GPX85_RS08385	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPX85_RS08400	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
GPX85_RS08405	ENOG4106M3D	hemolysin
GPX85_RS08410	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS08420	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
GPX85_RS08430	ENOG4105D01	(LipO)protein
GPX85_RS08435	ENOG4108Z4X	TRANSCRIPTIONal
GPX85_RS08465	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GPX85_RS08470	ENOG4108Z1B	Cyclase dehydrase
GPX85_RS08475	ENOG4105VDB	UPF0125 protein
GPX85_RS08480	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GPX85_RS08485	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GPX85_RS08500	ENOG4105CFG	Acts as a chaperone (By similarity)
GPX85_RS08505	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GPX85_RS08510	ENOG4105C1J	atp-dependent rna helicase
GPX85_RS08550	ENOG4105C4W	S-formylglutathione hydrolase
GPX85_RS08560	ENOG4105CC0	LysR family Transcriptional regulator
GPX85_RS08565	ENOG4108Z6B	deaminase
GPX85_RS08570	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GPX85_RS08575	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GPX85_RS08590	ENOG4105W1I	UPF0253 protein
GPX85_RS08595	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GPX85_RS08600	ENOG4108R96	Methyltransferase, YaeB family
GPX85_RS08605	ENOG4105NRA	50s ribosomal protein l31 type b
GPX85_RS08615	ENOG4105CFC	Transporter
GPX85_RS08620	ENOG4108UPT	UPF0178 protein
GPX85_RS08645	ENOG4105WP7	tRNA pseudouridine synthase C
GPX85_RS08650	ENOG4105DR9	pseudouridine synthase
GPX85_RS08655	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GPX85_RS08660	ENOG4105CTB	Polyprenyl synthetase
GPX85_RS08670	ENOG4105E14	MotA TolQ exbB proton channel
GPX85_RS08685	ENOG4105ETT	transcriptional Regulator, LysR family
GPX85_RS08695	ENOG4105M08	Membrane
GPX85_RS08700	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
GPX85_RS08705	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
GPX85_RS08710	ENOG4105EWT	decarboxylase family
GPX85_RS08715	ENOG4105BZU	Histidine kinase
GPX85_RS08725	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GPX85_RS08730	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
GPX85_RS08735	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
GPX85_RS08740	ENOG4105D01	(LipO)protein
GPX85_RS08745	ENOG4108UMI	ABC transporter, permease
GPX85_RS08750	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GPX85_RS08755	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GPX85_RS08760	ENOG4105D4X	repressor
GPX85_RS08765	ENOG4105C5Y	PTS System
GPX85_RS08770	ENOG4105CG3	alpha amylase, catalytic region
GPX85_RS08800	ENOG4105BZS	acriflavin resistance protein
GPX85_RS08810	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GPX85_RS08815	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GPX85_RS08820	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GPX85_RS08825	ENOG4108Z43	UPF0250 protein
GPX85_RS08830	ENOG4105DZ1	carboxypeptidase
GPX85_RS08835	ENOG4105K6T	rare lipoprotein A
GPX85_RS08840	ENOG4105CNI	cell division protein FtsW
GPX85_RS08850	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GPX85_RS08855	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GPX85_RS08860	ENOG4105DJF	DNA polymerase III, delta' subunit
GPX85_RS08865	ENOG4108U2H	Rare lipoprotein B
GPX85_RS08870	ENOG4105C8T	Leucyl-tRNA synthetase
GPX85_RS08875	ENOG4107PAI	alpha helical protein
GPX85_RS08880	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GPX85_RS08885	ENOG4108JU5	Magnesium and cobalt efflux protein
GPX85_RS08890	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GPX85_RS08895	ENOG4105C9A	Phoh family
GPX85_RS08905	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GPX85_RS08910	ENOG4108RS6	transposase
GPX85_RS08915	ENOG4105C5Y	PTS System
GPX85_RS08925	ENOG4105KZ7	phosphocarrier protein hpr
GPX85_RS08935	ENOG4105C6T	cysteine synthase
GPX85_RS08940	ENOG4105EXN	Sulfate transport protein CysZ
GPX85_RS08945	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GPX85_RS08950	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GPX85_RS08955	ENOG41081QG	Porin Gram-negative type
GPX85_RS08960	ENOG4108Q67	UPF0319 protein
GPX85_RS08965	ENOG4108Z6Z	Transcriptional regulator
GPX85_RS08970	ENOG4105G5H	Membrane
GPX85_RS08975	ENOG4107QX8	SPFH domain, Band 7 family protein
GPX85_RS08980	ENOG4107QR8	Thioredoxin
GPX85_RS08990	ENOG4105E1F	short-chain dehydrogenase reductase
GPX85_RS08995	ENOG4105ECP	epimerase
GPX85_RS09000	ENOG4108RE9	Phosphodiesterase
GPX85_RS09015	ENOG4108TU9	TRANSCRIPTIONal
GPX85_RS09020	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GPX85_RS09025	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GPX85_RS09030	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GPX85_RS09045	ENOG4105MDZ	Transcriptional activator rfaH
GPX85_RS09050	ENOG4105CAQ	asparagine synthetase
GPX85_RS09055	ENOG4105E2R	ROK family
GPX85_RS09060	ENOG4105CE4	GlcNAc 6-P deacetylase
GPX85_RS09065	ENOG4105CI1	PTS System
GPX85_RS09070	ENOG4105CX6	glutaminyL-tRNA synthetase
GPX85_RS09080	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GPX85_RS09085	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GPX85_RS09090	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GPX85_RS09095	ENOG4108S3P	Sporulation domain protein
GPX85_RS09100	ENOG4105E96	Colicin v production protein
GPX85_RS09105	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GPX85_RS09110	ENOG4105D3Y	Na H antiporter
GPX85_RS09115	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GPX85_RS09120	ENOG4105EIY	sodium-type flagellar protein motY
GPX85_RS09125	ENOG4108UYE	Lactoylglutathione lyase
GPX85_RS09130	ENOG4105CSM	endonuclease III
GPX85_RS09135	ENOG4105DZB	Electron transport complex
GPX85_RS09145	ENOG4105D6A	Electron transport complex
GPX85_RS09155	ENOG4108R3D	Electron transport complex
GPX85_RS09170	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GPX85_RS09185	ENOG4105CK2	sodium dicarboxylate symporter
GPX85_RS09195	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GPX85_RS09200	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPX85_RS09215	ENOG4105D9N	nucleoside
GPX85_RS09220	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GPX85_RS09230	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GPX85_RS09235	ENOG4105BZU	Histidine kinase
GPX85_RS09260	ENOG4105EJQ	L-serine dehydratase
GPX85_RS09265	ENOG4105CNG	UPF0061 protein
GPX85_RS09270	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GPX85_RS09275	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GPX85_RS09280	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GPX85_RS09285	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GPX85_RS09290	ENOG4105K70	DNA-binding protein
GPX85_RS09295	ENOG4105EIN	peptidylprolyl cis-trans isomerase
GPX85_RS09305	ENOG4105CAT	Cytidine monophosphate kinase
GPX85_RS09310	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GPX85_RS09315	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GPX85_RS09320	ENOG4105Q4A	inner membrane protein yciS
GPX85_RS09325	ENOG4105CFV	Tetratricopeptide repeat protein
GPX85_RS09330	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GPX85_RS09335	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
GPX85_RS09350	ENOG4105DCF	alanine dehydrogenase
GPX85_RS09355	ENOG4105EW9	transcriptional regulator AsnC family
GPX85_RS09360	ENOG4105CNU	cell division protein FtsK
GPX85_RS09380	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GPX85_RS09385	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
GPX85_RS09390	ENOG4105CCU	oxidase (Subunit III)
GPX85_RS09395	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GPX85_RS09400	ENOG4105E2S	oxidase) subunit II
GPX85_RS09410	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GPX85_RS09420	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
GPX85_RS09430	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS09435	ENOG4105K59	histidine triad (HIT) protein
GPX85_RS09460	ENOG4105D0Y	UPF0227 protein
GPX85_RS09470	ENOG4105C03	ribonuclease
GPX85_RS09475	ENOG4105EI2	Pseudouridine synthase
GPX85_RS09480	ENOG4108UHJ	MAF-like protein
GPX85_RS09485	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GPX85_RS09490	ENOG4105VGS	50s ribosomal protein l32
GPX85_RS09495	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GPX85_RS09500	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GPX85_RS09505	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GPX85_RS09510	ENOG4105CHR	reductase
GPX85_RS09515	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GPX85_RS09520	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GPX85_RS09525	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
GPX85_RS09530	ENOG4105HHA	aminodeoxychorismate lyase
GPX85_RS09535	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GPX85_RS09540	ENOG4107QRG	dna polymerase iii
GPX85_RS09545	ENOG4105F8V	Hydrolase, tatD family
GPX85_RS09550	ENOG4105CI1	PTS System
GPX85_RS09565	ENOG4105C8J	)-transporter
GPX85_RS09580	ENOG4108NRW	Phospholipase, patatin family
GPX85_RS09585	ENOG4105CA9	Pyruvate kinase
GPX85_RS09590	ENOG4105DAG	ROK family
GPX85_RS09595	ENOG4107R88	Chemotaxis protein (CheV)
GPX85_RS09600	ENOG4105UBK	short-chain dehydrogenase reductase
GPX85_RS09605	ENOG4105ERU	peptidase
GPX85_RS09620	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GPX85_RS09625	ENOG4105DK2	UPF0207 protein
GPX85_RS09645	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
GPX85_RS09650	ENOG4105CHM	Aminotransferase
GPX85_RS09655	ENOG4105E4F	Isochorismate synthase
GPX85_RS09665	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
GPX85_RS09670	ENOG4108IPT	Naphthoate synthase
GPX85_RS09675	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
GPX85_RS09680	ENOG4105CEY	Amp-dependent synthetase and ligase
GPX85_RS09705	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
GPX85_RS09715	ENOG4108XM1	transcriptional regulator AsnC family
GPX85_RS09720	ENOG4105C29	acyl-CoA thioesterase
GPX85_RS09790	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GPX85_RS09795	ENOG4105C09	Bile acid
GPX85_RS09800	ENOG4105CEY	Amp-dependent synthetase and ligase
GPX85_RS09825	ENOG4105C2C	drug resistance transporter, Bcr CflA
GPX85_RS09830	ENOG4105C5H	ABC transporter
GPX85_RS09845	ENOG4105N14	lysine exporter protein LysE YggA
GPX85_RS09855	ENOG4105X58	receptor
GPX85_RS09885	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GPX85_RS09890	ENOG4108NVR	Methyl-accepting chemotaxis
GPX85_RS09900	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GPX85_RS09915	ENOG4105C94	Transporter
GPX85_RS09920	ENOG4107R28	alpha amylase, catalytic region
GPX85_RS09935	ENOG4105DDV	Transcriptional regulator (LacI family
GPX85_RS09940	ENOG4105CS2	ec 3.2.1.21
GPX85_RS09945	ENOG4105DWF	phosphomethylpyrimidine kinase
GPX85_RS09950	ENOG4105C5Y	PTS System
GPX85_RS09960	ENOG4107R3K	hydrolase
GPX85_RS09965	ENOG4105D7K	pfkb domain protein
GPX85_RS09975	ENOG4107QSI	ABC, transporter
GPX85_RS09980	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GPX85_RS09985	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPX85_RS09990	ENOG4105C3U	ABC transporter
GPX85_RS09995	ENOG4108JQ7	(ABC) transporter
GPX85_RS10075	ENOG4105CHF	Glutathione S-transferase
GPX85_RS10080	ENOG4108DNC	Involved in acetate metabolism (By similarity)
GPX85_RS10085	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GPX85_RS10090	ENOG4105PQ6	UPF0208 membrane protein
GPX85_RS10095	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
GPX85_RS10100	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GPX85_RS10110	ENOG4105D1H	recombination factor protein RarA
GPX85_RS10115	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GPX85_RS10125	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GPX85_RS10130	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GPX85_RS10135	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GPX85_RS10140	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GPX85_RS10150	ENOG4105K9H	YciI-like protein
GPX85_RS10155	ENOG4105NAU	thioesterase Superfamily protein
GPX85_RS10160	ENOG4107835	probably involved in intracellular septation (By similarity)
GPX85_RS10165	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GPX85_RS10175	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GPX85_RS10180	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GPX85_RS10185	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GPX85_RS10190	ENOG4105DDQ	anthranilate synthase
GPX85_RS10195	ENOG4105CRQ	synthase (Component I)
GPX85_RS10205	ENOG4105DB7	PHP domain protein
GPX85_RS10210	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GPX85_RS10215	ENOG4105FE9	pseudouridine synthase
GPX85_RS10220	ENOG4108RS6	transposase
GPX85_RS10230	ENOG4108JJ8	(ABC) transporter
GPX85_RS10235	ENOG4108JJ9	ABC, transporter
GPX85_RS10240	ENOG4105C3M	thioredoxin reductase
GPX85_RS10270	ENOG4107GZ4	SanA protein
GPX85_RS10280	ENOG4107R1I	NAD-dependent malic enzyme
GPX85_RS10290	ENOG4105C8V	SAICAR synthetase
GPX85_RS10310	ENOG4108ZG0	Ompa motb domain protein
GPX85_RS10325	ENOG4105CQB	FAD linked oxidase domain protein
GPX85_RS10345	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GPX85_RS10360	ENOG4105C84	Histidine ammonia-lyase
GPX85_RS10365	ENOG4105CGP	Urocanate hydratase
GPX85_RS10370	ENOG41088SP	formiminoglutamate hydrolase
GPX85_RS10375	ENOG4105CI2	imidazolone-5-propionate hydrolase
GPX85_RS10380	ENOG4105CZE	histidine utilization repressor
GPX85_RS10395	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GPX85_RS10405	ENOG4105C44	Serine transporter
GPX85_RS10410	ENOG4105CQ2	DNA polymerase
GPX85_RS10425	ENOG4105WH1	Two component transcriptional regulator luxr family
GPX85_RS10465	ENOG4108MJ3	acetyltransferase
GPX85_RS10470	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GPX85_RS10475	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GPX85_RS10480	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GPX85_RS10485	ENOG4105KXC	Collagenase
GPX85_RS10495	ENOG4105FQ6	thiopurine methyltransferase
GPX85_RS10500	ENOG4107SDU	Methyl-accepting chemotaxis
GPX85_RS10505	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GPX85_RS10515	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
GPX85_RS10520	ENOG41067MG	lrgb family
GPX85_RS10545	ENOG4107FQX	Alpha-acetolactate decarboxylase
GPX85_RS10550	ENOG4105C7K	acetolactate synthase
GPX85_RS10585	ENOG4108RS6	transposase
GPX85_RS10590	ENOG4108Z4U	Ferredoxin
GPX85_RS10595	ENOG4105DZ0	fad dependent oxidoreductase
GPX85_RS10600	ENOG4107RCV	ABC transporter, permease
GPX85_RS10610	ENOG4105C4Y	ABC transporter
GPX85_RS10615	ENOG4105ETT	transcriptional Regulator, LysR family
GPX85_RS10630	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GPX85_RS10635	ENOG4105CFI	type iii restriction protein res subunit
GPX85_RS10640	ENOG4105I08	Pseudouridine synthase
GPX85_RS10645	ENOG4105C2C	drug resistance transporter, Bcr CflA
GPX85_RS10660	ENOG4107IFA	Lipase (EC 3.1.1.3)
GPX85_RS10665	ENOG4105CGD	Nad-dependent epimerase dehydratase
GPX85_RS10670	ENOG4105UQX	Mate efflux family protein
GPX85_RS10675	ENOG4108I0Y	(ABC) transporter
GPX85_RS10690	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GPX85_RS10695	ENOG4105D65	subunit l
GPX85_RS10700	ENOG4105HC0	Na H antiporter
GPX85_RS10705	ENOG4105MKQ	Monovalent cation H antiporter subunit C
GPX85_RS10715	ENOG4105SC1	monovalent cation H antiporter subunit E
GPX85_RS10720	ENOG41080TA	Multiple resistance and ph regulation protein f
GPX85_RS10725	ENOG4105KJM	monovalent cation h antiporter subunit g
GPX85_RS10735	ENOG4105E3Q	saccharopine dehydrogenase
GPX85_RS10740	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
GPX85_RS10765	ENOG4107QK7	reductase
GPX85_RS10770	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GPX85_RS10775	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GPX85_RS10780	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GPX85_RS10785	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPX85_RS10795	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GPX85_RS10800	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
GPX85_RS10805	ENOG4105C5X	domain protein
GPX85_RS10820	ENOG41067TZ	transcriptional regulator, MarR family
GPX85_RS10825	ENOG4105C94	Transporter
GPX85_RS10830	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS10835	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GPX85_RS10840	ENOG41080XP	Cbs domain
GPX85_RS10850	ENOG4105CGF	Aromatic amino acid aminotransferase
GPX85_RS10855	ENOG4105C5S	asparaginyl-tRNA synthetase
GPX85_RS10860	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
GPX85_RS10865	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GPX85_RS10875	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GPX85_RS10880	ENOG4105EJQ	L-serine dehydratase
GPX85_RS10885	ENOG4105C44	Serine transporter
GPX85_RS10890	ENOG4105P8F	nudix hydrolase
GPX85_RS10895	ENOG4105CRQ	synthase (Component I)
GPX85_RS10910	ENOG4105CM6	amino acid regulated cytosolic protein
GPX85_RS10920	ENOG4108JU8	Transcriptional regulator
GPX85_RS10925	ENOG4105D9U	N-acetyltransferase
GPX85_RS10935	ENOG4107AQZ	Membrane
GPX85_RS10940	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GPX85_RS10945	ENOG4108NVR	Methyl-accepting chemotaxis
GPX85_RS10950	ENOG4105C8P	)-transporter
GPX85_RS10955	ENOG4105BZU	Histidine kinase
GPX85_RS10960	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPX85_RS10980	ENOG4105CR4	methylisocitrate lyase
GPX85_RS10985	ENOG4105BZN	citrate synthase
GPX85_RS10990	ENOG4108I0Z	Aconitate hydratase
GPX85_RS10995	ENOG4105C7F	AcnD-accessory protein PrpF
GPX85_RS11000	ENOG4105DFH	Transport of potassium into the cell (By similarity)
GPX85_RS11035	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GPX85_RS11040	ENOG4105CTD	carboxy-peptidase
GPX85_RS11055	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
GPX85_RS11060	ENOG410829K	Lysine exporter protein (Lyse ygga)
GPX85_RS11065	ENOG4105BZG	amino acid carrier protein
GPX85_RS11080	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GPX85_RS11100	ENOG4105QNR	S1 RNA binding domain protein
GPX85_RS11105	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GPX85_RS11110	ENOG4105DY2	Paraquat-inducible protein b
GPX85_RS11115	ENOG4105H2K	paraquat-inducible protein a
GPX85_RS11120	ENOG4105BZ1	(ABC) transporter
GPX85_RS11125	ENOG4108ZGC	gaf domain protein
GPX85_RS11130	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
GPX85_RS11135	ENOG4105CN1	protease
GPX85_RS11145	ENOG4105CD8	aminopeptidase N
GPX85_RS11155	ENOG4105C7I	Dehydrogenase
GPX85_RS11160	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GPX85_RS11165	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
GPX85_RS11170	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GPX85_RS11175	ENOG4105C5H	ABC transporter
GPX85_RS11190	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
GPX85_RS11195	ENOG4105DAN	ATP-dependent protease
GPX85_RS11200	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
GPX85_RS11210	ENOG4105BZU	Histidine kinase
GPX85_RS11225	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GPX85_RS11230	ENOG4105Q9Y	Universal stress protein
GPX85_RS11235	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GPX85_RS11250	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPX85_RS11255	ENOG4105F38	ABC transporter, permease
GPX85_RS11260	ENOG4105D38	putrescine abc transporter
GPX85_RS11265	ENOG4107RUE	extracellular solute-binding protein family 1
GPX85_RS11270	ENOG4107RUE	extracellular solute-binding protein family 1
GPX85_RS11275	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GPX85_RS11290	ENOG4105QAX	Iron-sulfur
GPX85_RS11295	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GPX85_RS11325	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GPX85_RS11330	ENOG4105BZU	Histidine kinase
GPX85_RS11335	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPX85_RS11345	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
GPX85_RS11355	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GPX85_RS11360	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GPX85_RS11370	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
GPX85_RS11375	ENOG4106IUH	DTW domain containing protein
GPX85_RS11385	ENOG4107TT5	NLP P60 protein
GPX85_RS11395	ENOG4105FGM	Fructosamine kinase
GPX85_RS11400	ENOG4105K8R	UPF0145 protein
GPX85_RS11405	ENOG4105BZU	Histidine kinase
GPX85_RS11420	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GPX85_RS11430	ENOG4108R6K	riboflavin synthase, subunit alpha
GPX85_RS11460	ENOG4109015	Biopolymer transport protein exbD tolR
GPX85_RS11480	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GPX85_RS11485	ENOG4105BZU	Histidine kinase
GPX85_RS11490	ENOG4108V3W	Chemotaxis protein, CheW
GPX85_RS11500	ENOG4105CBS	Chea signal transduction histidine kinase
GPX85_RS11510	ENOG4108VYJ	response regulator receiver protein
GPX85_RS11515	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
GPX85_RS11540	ENOG4108IJ9	(ABC) transporter
GPX85_RS11545	ENOG4108RXX	maleylacetoacetate isomerase
GPX85_RS11555	ENOG4105F1J	Homogentisate 1,2-dioxygenase
GPX85_RS11560	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GPX85_RS11565	ENOG4107XTP	(EAL) domain protein
GPX85_RS11580	ENOG4108R4R	Iron-regulated virulence regulatory protein
GPX85_RS11590	ENOG4105CQ7	ATP-dependent helicase
GPX85_RS11605	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS11620	ENOG4105CFG	Acts as a chaperone (By similarity)
GPX85_RS11630	ENOG4105GR3	Histidine kinase
GPX85_RS11645	ENOG4105BZ1	(ABC) transporter
GPX85_RS11650	ENOG4105BZ1	(ABC) transporter
GPX85_RS11665	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GPX85_RS11670	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GPX85_RS11675	ENOG410667J	hydrolase
GPX85_RS11685	ENOG4107QXX	ABC transporter
GPX85_RS11690	ENOG4108MN8	Membrane
GPX85_RS11695	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GPX85_RS11700	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GPX85_RS11705	ENOG4105DR4	Methyltransferase
GPX85_RS11710	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GPX85_RS11715	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GPX85_RS11720	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GPX85_RS11740	ENOG4107EXC	regulatoR
GPX85_RS11745	ENOG4105E0F	Histidine kinase
GPX85_RS11760	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
GPX85_RS11780	ENOG4107IIZ	CRISPR-associated helicase, Cas3
GPX85_RS11785	ENOG4107SV5	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
GPX85_RS11790	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GPX85_RS11795	ENOG4108MRH	transcriptional regulatory protein
GPX85_RS11800	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GPX85_RS11810	ENOG4106M28	alanine racemase domain protein
GPX85_RS11820	ENOG4105C3U	ABC transporter
GPX85_RS11835	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPX85_RS11865	ENOG4107R88	Chemotaxis protein (CheV)
GPX85_RS11880	ENOG4107V40	secretion protein, HlyD family
GPX85_RS11895	ENOG4105CVG	Homoserine O-transsuccinylase
GPX85_RS11910	ENOG4108VKG	metal-dependent hydrolase
GPX85_RS11920	ENOG4105F04	LysR family Transcriptional regulator
GPX85_RS11945	ENOG4105BZS	acriflavin resistance protein
GPX85_RS11950	ENOG410624X	efflux transporter, rnd family, mfp subunit
GPX85_RS11960	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
GPX85_RS11965	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
GPX85_RS11980	ENOG4108ETY	sodium dicarboxylate symporter
GPX85_RS11990	ENOG4105C44	Serine transporter
GPX85_RS12000	ENOG4105XZD	Fe-S protein
GPX85_RS12010	ENOG4105VNH	ABC transporter solute-binding protein
GPX85_RS12015	ENOG4105CXZ	ABC transporter, permease
GPX85_RS12020	ENOG4108VGW	abc transporter atp-binding protein
GPX85_RS12025	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
GPX85_RS12030	ENOG4108W1A	pseudouridine synthase
GPX85_RS12035	ENOG4105C8J	)-transporter
GPX85_RS12050	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GPX85_RS12055	ENOG4108J59	Extracellular solute-binding protein, family 5
GPX85_RS12060	ENOG4108I5W	peptide transport system, permease protein
GPX85_RS12065	ENOG4108EU3	peptide transport system, permease
GPX85_RS12070	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
GPX85_RS12075	ENOG4108JQ2	peptide transport system atp-binding protein
GPX85_RS12100	ENOG4105GFG	DUF218 domain
GPX85_RS12110	ENOG4105C9M	aspartyl-trna synthetase
GPX85_RS12115	ENOG41081XQ	Conserved Protein
GPX85_RS12120	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
GPX85_RS12125	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
GPX85_RS12130	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPX85_RS12140	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPX85_RS12155	ENOG4105BZ4	penicillin-binding protein
GPX85_RS12160	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
GPX85_RS12165	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
GPX85_RS12175	ENOG4106371	Methyltransferase
GPX85_RS12180	ENOG4107S90	membrAne
GPX85_RS12185	ENOG4105ETE	Transcriptional regulator (LacI family
GPX85_RS12190	ENOG4105HP8	regulator of competence-specific genes
GPX85_RS12200	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GPX85_RS12205	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GPX85_RS12210	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GPX85_RS12215	ENOG4105RKX	Protein of unknown function (DUF2498)
GPX85_RS12220	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GPX85_RS12225	ENOG4107MBR	17 kDa surface antigen
GPX85_RS12230	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GPX85_RS12235	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
GPX85_RS12240	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GPX85_RS12245	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GPX85_RS12250	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GPX85_RS12255	ENOG4105VEQ	Cold shock protein
GPX85_RS12265	ENOG4108R99	pseudouridine synthase
GPX85_RS12270	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GPX85_RS12275	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GPX85_RS12285	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GPX85_RS12290	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GPX85_RS12295	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GPX85_RS12300	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GPX85_RS12305	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GPX85_RS12310	ENOG4107S6Z	Na H antiporter
GPX85_RS12320	ENOG4108RS6	transposase
GPX85_RS12325	ENOG4107RE1	Inosine-guanosine kinase
GPX85_RS12330	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GPX85_RS12335	ENOG41075W9	High frequency lysogenization protein HflD homolog
GPX85_RS12340	ENOG4107QTF	adenylosuccinate lyase
GPX85_RS12360	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GPX85_RS12375	ENOG4105CHR	reductase
GPX85_RS12385	ENOG4105D0M	Protease HtpX homolog
GPX85_RS12390	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GPX85_RS12395	ENOG4105DZ2	Transcriptional regulator
GPX85_RS12410	ENOG4107RAN	Peptidase, M16
GPX85_RS12415	ENOG4105EKQ	RNA-directed DNA polymerase
GPX85_RS12425	ENOG4105BZU	Histidine kinase
GPX85_RS12430	ENOG4105CCT	upf0313 protein
GPX85_RS12435	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS12440	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GPX85_RS12450	ENOG4105BZU	Histidine kinase
GPX85_RS12450	ENOG4105BZU	Histidine kinase
GPX85_RS12475	ENOG4105DWU	Membrane
GPX85_RS12480	ENOG4105DY8	decarboxylase
GPX85_RS12485	ENOG4106KNT	transcriptional regulator
GPX85_RS12490	ENOG4108EKI	Dehydrogenase
GPX85_RS12495	ENOG41090BQ	Glutaredoxin
GPX85_RS12510	ENOG4107QPN	acyl-Coa dehydrogenase
GPX85_RS12515	ENOG41067SE	Tetr family transcriptional regulator
GPX85_RS12535	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GPX85_RS12540	ENOG41082YX	Transcriptional regulator, arsr family
GPX85_RS12550	ENOG4105C8U	phosphate abc transporter
GPX85_RS12555	ENOG4105E2Z	phosphate ABC transporter (Permease
GPX85_RS12560	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GPX85_RS12565	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
GPX85_RS12570	ENOG4105D6J	arsenicaL-resistance protein
GPX85_RS12595	ENOG4105D6J	arsenicaL-resistance protein
GPX85_RS12600	ENOG41082YX	Transcriptional regulator, arsr family
GPX85_RS12605	ENOG4105CHH	sulfate transporter
GPX85_RS12615	ENOG4105C94	Transporter
GPX85_RS12625	ENOG4105CZV	ABC transporter
GPX85_RS12630	ENOG4105FDP	GntR family transcriptional regulator
GPX85_RS12640	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GPX85_RS12650	ENOG4108Z4V	iron-sulfur cluster assembly
GPX85_RS12655	ENOG4105C9B	Cysteine desulfurase
GPX85_RS12660	ENOG4105JRK	feS assembly protein SufD
GPX85_RS12665	ENOG4105C3K	feS assembly ATPase SufC
GPX85_RS12675	ENOG4108V0P	LemA family
GPX85_RS12680	ENOG4105D0M	Protease HtpX homolog
GPX85_RS12690	ENOG4105CKI	cobalamin synthesis protein
GPX85_RS12700	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS12705	ENOG4105DHF	Membrane
GPX85_RS12755	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GPX85_RS12760	ENOG4105UFD	tol-pal system protein YbgF
GPX85_RS12765	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GPX85_RS12770	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
GPX85_RS12780	ENOG4105M8F	Biopolymer transport protein exbD tolR
GPX85_RS12785	ENOG4105E02	MotA TolQ exbB proton channel
GPX85_RS12790	ENOG4107YD3	Thioesterase
GPX85_RS12805	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GPX85_RS12810	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GPX85_RS12815	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GPX85_RS12820	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GPX85_RS12825	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GPX85_RS12830	ENOG4105C8N	cysteinyl-tRNA synthetase
GPX85_RS12835	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GPX85_RS12840	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GPX85_RS12845	ENOG4105D58	Diguanylate phosphodiesterase
GPX85_RS12855	ENOG4105KK7	inner membrane protein YiaW
GPX85_RS12860	ENOG4105EFX	secretion protein, HlyD family
GPX85_RS12875	ENOG4105DVT	helicase
GPX85_RS12885	ENOG4106428	Protein of unknown function (DUF2496)
GPX85_RS12890	ENOG4105CGK	Exodeoxyribonuclease III
GPX85_RS12895	ENOG4106YG3	ABC transporter
GPX85_RS12900	ENOG4105DSP	amino acid AbC transporter
GPX85_RS12905	ENOG4105E89	ABC transporter
GPX85_RS12910	ENOG4108JEH	abc transporter atp-binding protein
GPX85_RS12920	ENOG4105C6N	Formate acetyltransferase
GPX85_RS12930	ENOG4105F1A	Pyruvate formate-lyase
GPX85_RS12935	ENOG4105XWI	UPF0304 protein
GPX85_RS12945	ENOG4105CYN	Serine protein kinase
GPX85_RS12950	ENOG4106AKX	UPF0229 protein
GPX85_RS12955	ENOG4105ED1	spovr family
GPX85_RS12960	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GPX85_RS12965	ENOG4105W49	UPF0434 protein
GPX85_RS12970	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GPX85_RS12975	ENOG4105BZ1	(ABC) transporter
GPX85_RS12980	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
GPX85_RS12990	ENOG4105D60	lipoprotein releasing system transmembrane protein
GPX85_RS12995	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GPX85_RS13000	ENOG4105D60	lipoprotein releasing system transmembrane protein
GPX85_RS13010	ENOG4108JA2	transcriptioN-repair coupling factor
GPX85_RS13025	ENOG4108JUA	Transcriptional regulator
GPX85_RS13030	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
GPX85_RS13035	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GPX85_RS13040	ENOG4105CEP	NADH dehydrogenase
GPX85_RS13045	ENOG4108EKI	Dehydrogenase
GPX85_RS13050	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GPX85_RS13055	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GPX85_RS13060	ENOG4105DFD	Na H antiporter
GPX85_RS13065	ENOG4106V8H	Nucleoid-associated protein
GPX85_RS13075	ENOG4105E68	Sulfatase
GPX85_RS13195	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GPX85_RS13205	ENOG4105CAR	Terminase, large subunit
GPX85_RS13240	ENOG4105KUS	lysozyme
GPX85_RS13270	ENOG4108MXB	Protein of unknown function (DUF968)
GPX85_RS13335	ENOG4108XTP	Transcriptional regulator
GPX85_RS13340	ENOG4108T1M	outer membrane protein x
GPX85_RS13360	ENOG4108HJ1	Uncharacterized conserved protein (DUF2303)
GPX85_RS13455	ENOG41080IJ	Diacylglycerol kinase
GPX85_RS13460	ENOG4105DIJ	Phosphoethanolamine transferase
GPX85_RS13465	ENOG4105CJW	magnesium transporter
GPX85_RS13475	ENOG4105WBD	4-oxalocrotonate tautomerase
GPX85_RS13485	ENOG4108KTG	Membrane protein, drug metabolite transporter
GPX85_RS13490	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GPX85_RS13495	ENOG4108ZT1	Transcriptional regulator
GPX85_RS13500	ENOG4105CEY	Amp-dependent synthetase and ligase
GPX85_RS13505	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
GPX85_RS13595	ENOG4108ZZ3	UPF0260 protein
GPX85_RS13600	ENOG4105KRS	Proteinase inhibitor
GPX85_RS13605	ENOG4105BZU	Histidine kinase
GPX85_RS13610	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GPX85_RS13615	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GPX85_RS13620	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GPX85_RS13625	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GPX85_RS13630	ENOG4105WD1	Membrane
GPX85_RS13635	ENOG4105I93	response regulator
GPX85_RS13640	ENOG4105EJC	lysr family transcriptional regulator
GPX85_RS13645	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GPX85_RS13650	ENOG4105CHU	acetyl-coa acetyltransferase
GPX85_RS13655	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GPX85_RS13660	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GPX85_RS13665	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
GPX85_RS13670	ENOG4108GAE	asmA family
GPX85_RS13675	ENOG4105DBI	uridine monophosphokinase
GPX85_RS13680	ENOG4105D1F	ATP-binding protein
GPX85_RS13695	ENOG4107SXA	Phosphorylase
GPX85_RS13705	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GPX85_RS13710	ENOG4108ZAF	Molybdopterin
GPX85_RS13715	ENOG4105M00	molybdopterin converting factor, subunit 1
GPX85_RS13720	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GPX85_RS13725	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GPX85_RS13730	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GPX85_RS13735	ENOG4105CHW	UPF0052 protein
GPX85_RS13740	ENOG4105CVE	Lytic murein transglycosylase
GPX85_RS13745	ENOG4105VNG	YcgL domain-containing protein
GPX85_RS13750	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GPX85_RS13755	ENOG4107QMS	site-determining protein
GPX85_RS13760	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GPX85_RS13765	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
GPX85_RS13770	ENOG4105CEY	Amp-dependent synthetase and ligase
GPX85_RS13775	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GPX85_RS13790	ENOG41072GX	Peptidase M22 Glycoprotease
GPX85_RS13795	ENOG4105DVT	helicase
GPX85_RS13805	ENOG4105CIY	formyltetrahydrofolate deformylase
GPX85_RS13810	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GPX85_RS13815	ENOG4105D07	Signal peptide peptidase, SppA
GPX85_RS13820	ENOG4105HDK	L-asparaginase
GPX85_RS13825	ENOG4105VUT	cytoplasmic protein
GPX85_RS13835	ENOG4105E0X	reductase
GPX85_RS13840	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GPX85_RS13845	ENOG4105DSB	aldose 1-epimerase
GPX85_RS13850	ENOG4105DHI	Methyltransferase
GPX85_RS13865	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
GPX85_RS13870	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
GPX85_RS13875	ENOG4105C08	Histidine kinase
GPX85_RS13880	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
GPX85_RS13900	ENOG4105N1F	Hnh endonuclease
GPX85_RS13905	ENOG4108WUH	Transcriptional regulator, TetR family
GPX85_RS13910	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
GPX85_RS13920	ENOG4108ESY	Metal dependent phosphohydrolase
GPX85_RS13925	ENOG4105C5H	ABC transporter
GPX85_RS13935	ENOG4107QPB	Beta-lactamase domain protein
GPX85_RS13955	ENOG4105D5T	phosphonate abc transporter
GPX85_RS13960	ENOG4105S7S	phosphonate abc transporter
GPX85_RS13965	ENOG4105S7S	phosphonate abc transporter
GPX85_RS13970	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS13975	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GPX85_RS13980	ENOG4105M2J	Glutaredoxin
GPX85_RS13985	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GPX85_RS14000	ENOG410903C	(LipO)protein
GPX85_RS14010	ENOG4108V3W	Chemotaxis protein, CheW
GPX85_RS14020	ENOG4107QJE	Chromosome Partitioning Protein
GPX85_RS14025	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GPX85_RS14030	ENOG4105CBS	Chea signal transduction histidine kinase
GPX85_RS14035	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
GPX85_RS14040	ENOG4108VYJ	response regulator receiver protein
GPX85_RS14045	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPX85_RS14050	ENOG4107R21	site-determining protein
GPX85_RS14055	ENOG4105FZW	flagellar biosynthesis regulator FlhF
GPX85_RS14060	ENOG4105D7B	Flagellar biosynthesis protein flha
GPX85_RS14065	ENOG4108BY2	phosphohistidine phosphatase
GPX85_RS14070	ENOG4108JQM	Insulinase (Peptidase family M16)
GPX85_RS14075	ENOG4106ZCM	YecM protein
GPX85_RS14080	ENOG4105C75	arginyL-tRNA synthetase
GPX85_RS14095	ENOG4105CE1	Ferrous iron transport protein b
GPX85_RS14100	ENOG4105XFK	Ferrous iron transport protein A
GPX85_RS14110	ENOG4105NXV	High-affinity zinc uptake system protein
GPX85_RS14115	ENOG4105FDK	ABC transporter
GPX85_RS14120	ENOG4105FAV	ABC, transporter
GPX85_RS14125	ENOG4107S6Z	Na H antiporter
GPX85_RS14135	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GPX85_RS14140	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GPX85_RS14145	ENOG4105C7S	Dehydrogenase
GPX85_RS14150	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GPX85_RS14155	ENOG4105E33	succinate dehydrogenase
GPX85_RS14160	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GPX85_RS14165	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GPX85_RS14170	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GPX85_RS14175	ENOG4105BZN	citrate synthase
GPX85_RS14180	ENOG4107QNR	UPF0135 protein
GPX85_RS14190	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
GPX85_RS14195	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
GPX85_RS14200	ENOG4105EV9	Alpha Beta Hydrolase
GPX85_RS14205	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GPX85_RS14210	ENOG41067MG	lrgb family
GPX85_RS14220	ENOG4105CMU	LysR family (Transcriptional regulator
GPX85_RS14230	ENOG41090R7	Ferric uptake
GPX85_RS14235	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GPX85_RS14240	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GPX85_RS14245	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GPX85_RS14250	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
GPX85_RS14260	ENOG4105MH2	YfcL protein
GPX85_RS14265	ENOG4108BPE	-transporting atpase
GPX85_RS14270	ENOG4105EN6	Membrane
GPX85_RS14275	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GPX85_RS14280	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GPX85_RS14290	ENOG4105D00	flagellar biosynthetic protein flhB
GPX85_RS14295	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GPX85_RS14300	ENOG4105VS8	Flagellar biosynthetic protein fliq
GPX85_RS14305	ENOG4105CN7	Flagellar biosynthetic protein FliP
GPX85_RS14310	ENOG4105VTB	flagellar biosynthesis protein fliO
GPX85_RS14315	ENOG4105DD5	Flagellar motor switch protein
GPX85_RS14320	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GPX85_RS14340	ENOG4108JIR	Flagellum-specific ATP synthase
GPX85_RS14350	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GPX85_RS14355	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GPX85_RS14365	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPX85_RS14370	ENOG4105BZU	Histidine kinase
GPX85_RS14375	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPX85_RS14380	ENOG4105MQ3	flagellar protein FliS
GPX85_RS14390	ENOG4107W9T	flagellar hook-associated
GPX85_RS14395	ENOG41063QE	flagellar protein FlaG
GPX85_RS14400	ENOG4105I03	Flagellin
GPX85_RS14405	ENOG4105I03	Flagellin
GPX85_RS14410	ENOG4105I03	Flagellin
GPX85_RS14415	ENOG4105QZU	Inner membrane protein YfeZ
GPX85_RS14430	ENOG4105KUZ	arsenate reductase
GPX85_RS14435	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GPX85_RS14450	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GPX85_RS14455	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GPX85_RS14460	ENOG4105RH4	Glycine cleavage system transcriptional repressor
GPX85_RS14465	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPX85_RS14470	ENOG4105C8Q	Methyl-accepting chemotaxis
GPX85_RS14485	ENOG4105ERG	peptidase m48, ste24p
GPX85_RS14490	ENOG4105K89	arsenate reductase
GPX85_RS14495	ENOG4105CS1	NAD(P)H quinone oxidoreductase
GPX85_RS14515	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GPX85_RS14520	ENOG41063JG	Transcriptional regulator
GPX85_RS14525	ENOG4108YY7	Invasion gene expression up-regulator SirB
GPX85_RS14530	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GPX85_RS14535	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GPX85_RS14540	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GPX85_RS14550	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GPX85_RS14555	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GPX85_RS14560	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GPX85_RS14565	ENOG4105C3G	gtp-binding protein
GPX85_RS14645	ENOG4105I03	Flagellin
GPX85_RS14650	ENOG4105I03	Flagellin
GPX85_RS14665	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GPX85_RS14670	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GPX85_RS14675	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GPX85_RS14680	ENOG4105CGA	flagellar basal-body rod protein FlgG
GPX85_RS14685	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GPX85_RS14690	ENOG4105BZE	flagellar hook protein, FlgE
GPX85_RS14695	ENOG4105W00	Flagellar hook capping protein
GPX85_RS14700	ENOG4108ZC9	flagellar basal-body rod protein flgc
GPX85_RS14705	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GPX85_RS14715	ENOG4107R88	Chemotaxis protein (CheV)
GPX85_RS14760	ENOG4105CDV	Ompa motb domain protein
GPX85_RS14765	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GPX85_RS14770	ENOG4105C59	p-type ATPase
GPX85_RS14775	ENOG4105E2D	ec 3.2.1.52
GPX85_RS14790	ENOG4108DG9	Smr protein MutS2
GPX85_RS14795	ENOG4105FE9	pseudouridine synthase
GPX85_RS14800	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GPX85_RS14805	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GPX85_RS14810	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GPX85_RS14815	ENOG4105E7A	Glutamine amidotransferase
GPX85_RS14820	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GPX85_RS14825	ENOG4107QPN	acyl-Coa dehydrogenase
GPX85_RS14835	ENOG4108JDX	DNA polymerase iii, epsilon subunit
GPX85_RS14840	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GPX85_RS14845	ENOG4105D1A	Methyltransferase
GPX85_RS14850	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GPX85_RS14855	ENOG4105E9H	Lytic Murein transglycosylase
GPX85_RS14870	ENOG4105BZU	Histidine kinase
GPX85_RS14880	ENOG4108YZA	Nitrogen regulatory protein pii
GPX85_RS14885	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GPX85_RS14895	ENOG4105C0B	DNA polymerase III (alpha subunit)
GPX85_RS14900	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GPX85_RS14905	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPX85_RS14910	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPX85_RS14915	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GPX85_RS14920	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPX85_RS14925	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
GPX85_RS14935	ENOG4105DZP	Membrane-associated zinc metalloprotease
GPX85_RS14940	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GPX85_RS14945	ENOG4105KNE	Phosphatidate cytidylyltransferase
GPX85_RS14950	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GPX85_RS14955	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GPX85_RS14960	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GPX85_RS14965	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GPX85_RS14970	ENOG4105CE9	30S ribosomal protein S2
GPX85_RS14975	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GPX85_RS14980	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GPX85_RS14985	ENOG4108T8E	UPF0325 protein
GPX85_RS14990	ENOG4108ZAI	phosphatidylglycerophosphatase a
GPX85_RS15000	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GPX85_RS15005	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GPX85_RS15020	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GPX85_RS15025	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GPX85_RS15030	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GPX85_RS15035	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GPX85_RS15040	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
GPX85_RS15050	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GPX85_RS15055	ENOG4105C7N	Xanthine uracil vitamin C permease
GPX85_RS15060	ENOG4105CIN	aminoacyl-histidine dipeptidase
GPX85_RS15065	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPX85_RS15070	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPX85_RS15080	ENOG4105C8J	)-transporter
GPX85_RS15090	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GPX85_RS15100	ENOG4105CJ2	(LipO)protein
GPX85_RS15105	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
GPX85_RS15110	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPX85_RS15115	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPX85_RS15120	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPX85_RS15125	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPX85_RS15130	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPX85_RS15135	ENOG4105M85	Bola protein
GPX85_RS15140	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GPX85_RS15150	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GPX85_RS15215	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GPX85_RS15220	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GPX85_RS15225	ENOG4105C34	Pseudouridine synthase
GPX85_RS15230	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPX85_RS15235	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
GPX85_RS15245	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GPX85_RS15250	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
GPX85_RS15255	ENOG4107SC1	transglycosylase
GPX85_RS15275	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GPX85_RS15280	ENOG4108HRK	Histidine kinase
GPX85_RS15285	ENOG4108NEV	two component transcriptional regulator, LytTR family
GPX85_RS15290	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
GPX85_RS15295	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GPX85_RS15310	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GPX85_RS15315	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GPX85_RS15320	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GPX85_RS15325	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GPX85_RS15330	ENOG4105DTN	riboflavin biosynthesis protein ribF
GPX85_RS15335	ENOG4105CJR	Integral membrane protein (MviN
GPX85_RS15340	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GPX85_RS15345	ENOG41080HT	Transcriptional regulator, arsr family
GPX85_RS15350	ENOG41063Z6	transcriptional regulator, lysR family
GPX85_RS15360	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GPX85_RS15365	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GPX85_RS15370	ENOG4105HF0	Membrane
GPX85_RS15375	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
GPX85_RS15380	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GPX85_RS15385	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
GPX85_RS15390	ENOG4105CPC	Aldo Keto reductase
GPX85_RS15400	ENOG4105CRK	lysyL-tRNA synthetase
GPX85_RS15410	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GPX85_RS15415	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GPX85_RS15420	ENOG4105C1J	atp-dependent rna helicase
GPX85_RS15425	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GPX85_RS15430	ENOG4105BZU	Histidine kinase
GPX85_RS15445	ENOG4108YYD	acetyltransferase
GPX85_RS15450	ENOG4105XPQ	lipid carrier protein
GPX85_RS15455	ENOG4105BZU	Histidine kinase
GPX85_RS15460	ENOG4105CFP	Peptidase U32
GPX85_RS15465	ENOG4106RZ4	Peptidase U32
GPX85_RS15475	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GPX85_RS15480	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GPX85_RS15490	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GPX85_RS15500	ENOG4105CHV	Transcription elongation factor NusA
GPX85_RS15505	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GPX85_RS15525	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GPX85_RS15530	ENOG4105EEI	dihydropteroate synthase
GPX85_RS15535	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GPX85_RS15540	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GPX85_RS15545	ENOG4105HBR	Rna-binding protein
GPX85_RS15550	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GPX85_RS15555	ENOG4107QE9	Inherit from COG: Membrane
GPX85_RS15560	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GPX85_RS15565	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GPX85_RS15570	ENOG4105DR5	peptidase
GPX85_RS15580	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GPX85_RS15585	ENOG4105IPI	Membrane
GPX85_RS15590	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GPX85_RS15595	ENOG4105BZU	Histidine kinase
GPX85_RS15600	ENOG4105DEF	Extracellular solute-binding protein, family 5
GPX85_RS15615	ENOG4105C3U	ABC transporter
GPX85_RS15620	ENOG4108JQ7	(ABC) transporter
GPX85_RS15630	ENOG4105E2D	ec 3.2.1.52
GPX85_RS15635	ENOG4105E2V	Glycosyltransferase 36
GPX85_RS15640	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GPX85_RS15645	ENOG4107QKW	extracellular solute-binding protein family 1
GPX85_RS15655	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPX85_RS15665	ENOG4108YZA	Nitrogen regulatory protein pii
GPX85_RS15670	ENOG4105XTV	UPF0231 protein
GPX85_RS15675	ENOG4105BZW	Glycerate kinase
GPX85_RS15680	ENOG4105D05	Receptor
GPX85_RS15685	ENOG410804D	Sensor Signal Transduction Histidine Kinase
GPX85_RS15690	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GPX85_RS15705	ENOG4105DIK	(ABC) transporter
GPX85_RS15740	ENOG4107QIJ	Aconitate hydratase 2
GPX85_RS15745	ENOG4105D78	K07001 NTE family protein
GPX85_RS15755	ENOG4105CQ7	ATP-dependent helicase
GPX85_RS15760	ENOG4105PW4	Sugar fermentation stimulation protein homolog
GPX85_RS15765	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPX85_RS15770	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GPX85_RS15775	ENOG4105DJ0	Poly(A) Polymerase
GPX85_RS15780	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPX85_RS15785	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GPX85_RS15790	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GPX85_RS15795	ENOG4105E3A	(ABC) transporter
GPX85_RS15800	ENOG4105DA5	(ABC) transporter
GPX85_RS15805	ENOG41077A9	carbonic anhydrase
GPX85_RS15810	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GPX85_RS15820	ENOG410630P	Transcriptional regulator
GPX85_RS15825	ENOG4107QN2	dihydrolipoyl dehydrogenase
GPX85_RS15830	ENOG4107QSN	dihydrolipoamide acetyltransferase
GPX85_RS15835	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GPX85_RS15840	ENOG41073TP	transcriptional regulator
GPX85_RS15845	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GPX85_RS15850	ENOG4105T95	Thiol disulfide interChange protein
GPX85_RS15855	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GPX85_RS15860	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
GPX85_RS15870	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GPX85_RS15875	ENOG4105X0D	Fimbrial protein
GPX85_RS15880	ENOG4107QHF	type ii secretion system protein e
GPX85_RS15885	ENOG4105D7Q	type ii secretion system
GPX85_RS15890	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GPX85_RS15895	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GPX85_RS15900	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
GPX85_RS15905	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
GPX85_RS15910	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPX85_RS15915	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPX85_RS15920	ENOG4105IPS	esterase
GPX85_RS15925	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GPX85_RS15930	ENOG4108SX3	cytoplasmic protein
GPX85_RS15940	ENOG4105DFG	type I secretion outer membrane protein
GPX85_RS15950	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GPX85_RS15955	ENOG4108NVR	Methyl-accepting chemotaxis
GPX85_RS15960	ENOG4105I7R	Adenylate cyclase
GPX85_RS15965	ENOG4107IX6	phosphate transport regulator
GPX85_RS15970	ENOG4105CJ3	phosphate transporter
GPX85_RS15975	ENOG4106MWK	domain protein
GPX85_RS15980	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GPX85_RS15985	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GPX85_RS15990	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GPX85_RS15995	ENOG4105DXN	mazG family
GPX85_RS16000	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GPX85_RS16005	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GPX85_RS16010	ENOG4105BZU	Histidine kinase
GPX85_RS16015	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GPX85_RS16020	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GPX85_RS16025	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
GPX85_RS16030	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GPX85_RS16035	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GPX85_RS16040	ENOG4105C3F	Signal peptidase i
GPX85_RS16045	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GPX85_RS16050	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
GPX85_RS16055	ENOG4105VQK	sigma E regulatory protein, MucB RseB
GPX85_RS16065	ENOG4105EMN	RNA polymerase sigma factor
GPX85_RS16070	ENOG4108IYU	L-aspartate oxidase
GPX85_RS16080	ENOG4105Y75	tpr repeat protein
GPX85_RS16085	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GPX85_RS16100	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GPX85_RS16105	ENOG4105D0A	hydroxylase
GPX85_RS16115	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GPX85_RS16125	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GPX85_RS16130	ENOG4105E66	phosphoriboisomerase A
GPX85_RS16135	ENOG4108JQ1	Dehydrogenase
GPX85_RS16140	ENOG4108ZP8	Acetolactate synthase small subunit
GPX85_RS16145	ENOG4105C7K	acetolactate synthase
GPX85_RS16150	ENOG4108IQE	Amp-dependent synthetase and ligase
GPX85_RS16155	ENOG41064T2	transcriptional regulator, lysR family
GPX85_RS16170	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GPX85_RS16175	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GPX85_RS16180	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GPX85_RS16185	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GPX85_RS16280	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GPX85_RS16300	ENOG4105YB8	TM2 domain containing protein
GPX85_RS16305	ENOG4108KZE	transcriptional regulator
GPX85_RS16345	ENOG4105VZ1	Replication Protein
GPX85_RS16355	ENOG4105NI8	Cytosine-specific methyltransferase
GPX85_RS16375	ENOG4108K5H	permease YjgP YjgQ family protein
GPX85_RS16380	ENOG4108M8S	permease YjgP YjgQ family protein
GPX85_RS16385	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GPX85_RS16390	ENOG4105MYG	DNA polymerase iii, chi subunit
GPX85_RS16395	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GPX85_RS16410	ENOG4105K3M	)-transporter
GPX85_RS16415	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
GPX85_RS16420	ENOG4108IAB	Phoh family
GPX85_RS16425	ENOG4105DBV	ornithine carbamoyltransferase
GPX85_RS16430	ENOG4105CXT	aspartate transcarbamylase
GPX85_RS16435	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
GPX85_RS16440	ENOG4105KME	endoribonuclease L-psp
GPX85_RS16445	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GPX85_RS16450	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GPX85_RS16455	ENOG4105VFK	BolA family
GPX85_RS16465	ENOG4105E3I	toluene tolerance
GPX85_RS16470	ENOG4107PE3	Mammalian cell entry related domain protein
GPX85_RS16475	ENOG4105CY3	ABC transporter, permease
GPX85_RS16480	ENOG4105DHJ	ABC, transporter
GPX85_RS16490	ENOG4105C2X	Arabinose 5-phosphate isomerase
GPX85_RS16495	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
GPX85_RS16505	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
GPX85_RS16510	ENOG4108IUZ	ABC transporter
GPX85_RS16515	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPX85_RS16520	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GPX85_RS16525	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GPX85_RS16535	ENOG41080Z8	PHOSPHOCARRIER protein
GPX85_RS16545	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GPX85_RS16550	ENOG4105N42	UPF0307 protein
GPX85_RS16555	ENOG4107T0D	ABC, transporter
GPX85_RS16565	ENOG4105DP9	ABC transporter
GPX85_RS16570	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GPX85_RS16575	ENOG4105DFU	Cell wall formation (By similarity)
GPX85_RS16580	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GPX85_RS16585	ENOG4105F0N	pyrophosphate phospho-hydrolase
GPX85_RS16590	ENOG41066HZ	AIG2-like family
GPX85_RS16600	ENOG4105CFU	surface antigen
GPX85_RS16615	ENOG4108UUE	Transcriptional regulator
GPX85_RS16630	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GPX85_RS16650	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
GPX85_RS16655	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
GPX85_RS16660	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GPX85_RS16665	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GPX85_RS16670	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
GPX85_RS16680	ENOG4105C1J	atp-dependent rna helicase
GPX85_RS16685	ENOG4107YB6	acetyltransferase, (GNAT) family
GPX85_RS16695	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GPX85_RS16705	ENOG4108ZT0	50S ribosomal protein l17
GPX85_RS16710	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GPX85_RS16715	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GPX85_RS16720	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GPX85_RS16725	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPX85_RS16735	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GPX85_RS16740	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GPX85_RS16745	ENOG4105VPB	50S ribosomal protein L30
GPX85_RS16750	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GPX85_RS16760	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GPX85_RS16765	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GPX85_RS16770	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GPX85_RS16775	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPX85_RS16780	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GPX85_RS16785	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GPX85_RS16790	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GPX85_RS16795	ENOG41083MP	50s ribosomal protein l29
GPX85_RS16800	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GPX85_RS16805	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GPX85_RS16810	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GPX85_RS16815	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GPX85_RS16820	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPX85_RS16825	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GPX85_RS16830	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GPX85_RS16835	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GPX85_RS16840	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GPX85_RS16845	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GPX85_RS16850	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GPX85_RS16855	ENOG4108UV7	flagellar protein motX
GPX85_RS16860	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GPX85_RS16865	ENOG4105D44	asparaginase
GPX85_RS16870	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GPX85_RS16885	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GPX85_RS16890	ENOG4105C5H	ABC transporter
GPX85_RS16900	ENOG4105DNZ	Alpha Beta Hydrolase
GPX85_RS16910	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
GPX85_RS16915	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GPX85_RS16925	ENOG4105C26	Dehydrogenase
GPX85_RS16940	ENOG4105DDQ	anthranilate synthase
GPX85_RS16950	ENOG4105C31	Tryptophanyl-tRNA synthetase
GPX85_RS16955	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GPX85_RS16960	ENOG4105DJV	ribulose-phosphate 3-epimerase
GPX85_RS16965	ENOG4105DFE	Dna adenine methylase
GPX85_RS16980	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GPX85_RS16985	ENOG4105E4G	Type IV pilus
GPX85_RS17010	ENOG4108JQC	penicillin-binding protein 1A
GPX85_RS17025	ENOG4105CH7	arginosuccinase
GPX85_RS17030	ENOG4105CDH	Citrulline--aspartate ligase
GPX85_RS17040	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GPX85_RS17045	ENOG4105CWC	Acetylornithine deacetylase
GPX85_RS17050	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GPX85_RS17060	ENOG4105D7W	serine acetyltransferase
GPX85_RS17065	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GPX85_RS17070	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GPX85_RS17075	ENOG4107YZP	Rhodanese domain protein
GPX85_RS17080	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
GPX85_RS17090	ENOG4105E33	succinate dehydrogenase
GPX85_RS17095	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GPX85_RS17100	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GPX85_RS17105	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GPX85_RS17110	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GPX85_RS17115	ENOG4105KT7	mgtC SapB transporter
GPX85_RS17120	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GPX85_RS17125	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GPX85_RS17150	ENOG4105CP7	Triose-phosphate isomerase
GPX85_RS17160	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GPX85_RS17165	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GPX85_RS17170	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GPX85_RS17175	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GPX85_RS17185	ENOG4105ETE	Transcriptional regulator (LacI family
GPX85_RS17190	ENOG4105C25	Primosomal protein n'
GPX85_RS17195	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GPX85_RS17200	ENOG4105C6K	Malic enzyme
GPX85_RS17205	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
GPX85_RS17210	ENOG4105C28	cystathionine
GPX85_RS17215	ENOG4105CFH	Aspartokinase
GPX85_RS17220	ENOG4105SYT	Methylenetetrahydrofolate reductase
GPX85_RS17225	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
GPX85_RS17230	ENOG4105CBT	Fructose-1,6-bisphosphatase
GPX85_RS17235	ENOG4105CTQ	phosphohexokinase
GPX85_RS17240	ENOG41076HS	cation diffusion facilitator family transporter
GPX85_RS17250	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GPX85_RS17255	ENOG4105E0F	Histidine kinase
GPX85_RS17260	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GPX85_RS17265	ENOG4105VEQ	Cold shock protein
GPX85_RS17270	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
GPX85_RS17275	ENOG4108IJ0	Aspartate ammonia-lyase
GPX85_RS17280	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GPX85_RS17285	ENOG4105CSX	c4-dicarboxylate anaerobic carrier