locus-tag	class	description
GPX86_RS00040	COG3772	lysozyme
GPX86_RS00100	COG3083	sulfuric ester hydrolase activity
GPX86_RS00110	COG3081	Nucleoid-associated protein
GPX86_RS00115	COG1757	Na H antiporter
GPX86_RS00120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPX86_RS00125	COG2095	MarC family integral membrane protein
GPX86_RS00130	COG1454	alcohol dehydrogenase
GPX86_RS00130	COG1012	belongs to the aldehyde dehydrogenase family
GPX86_RS00135	COG1252	NADH dehydrogenase
GPX86_RS00150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPX86_RS00160	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPX86_RS00165	COG1136	(ABC) transporter
GPX86_RS00170	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPX86_RS00180	COG0658	competence protein
GPX86_RS00180	COG2333	competence protein COMEC
GPX86_RS00185	COG1132	(ABC) transporter
GPX86_RS00190	COG1663	tetraacyldisaccharide 4'-kinase activity
GPX86_RS00200	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GPX86_RS00205	COG2719	SpoVR family
GPX86_RS00210	COG2718	Belongs to the UPF0229 family
GPX86_RS00215	COG2766	serine protein kinase
GPX86_RS00225	COG3013	Belongs to the UPF0304 family
GPX86_RS00230	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPX86_RS00240	COG1882	Formate acetyltransferase
GPX86_RS00260	COG4215	(ABC) transporter
GPX86_RS00270	COG0708	Exodeoxyribonuclease III
GPX86_RS00285	COG1199	ATP-dependent helicase activity
GPX86_RS00300	COG1566	PFAM secretion protein HlyD family protein
GPX86_RS00315	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPX86_RS00320	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPX86_RS00325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPX86_RS00330	COG0215	cysteine-tRNA ligase activity
GPX86_RS00335	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GPX86_RS00340	COG0632	four-way junction helicase activity
GPX86_RS00345	COG2255	four-way junction helicase activity
GPX86_RS00350	COG1271	oxidase subunit
GPX86_RS00355	COG1294	oxidase, subunit
GPX86_RS00360	COG4890	Cyd operon protein YbgT
GPX86_RS00370	COG0824	Thioesterase
GPX86_RS00375	COG0811	peptide transport
GPX86_RS00395	COG2885	chlorophyll binding
GPX86_RS00400	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GPX86_RS00405	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GPX86_RS00420	COG2311	Membrane
GPX86_RS00430	COG3036	rescue of stalled ribosome
GPX86_RS00450	COG0501	Belongs to the peptidase M48B family
GPX86_RS00455	COG1704	LemA family
GPX86_RS00460	COG0719	Fe-S assembly protein
GPX86_RS00465	COG0396	ATPase activity
GPX86_RS00470	COG0719	Fe-S assembly protein
GPX86_RS00475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPX86_RS00490	COG2166	iron-sulfur cluster assembly
GPX86_RS00500	COG2188	Transcriptional regulator
GPX86_RS00505	COG1131	(ABC) transporter
GPX86_RS00515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPX86_RS00525	COG0659	secondary active sulfate transmembrane transporter activity
GPX86_RS00530	COG0640	Transcriptional regulator
GPX86_RS00535	COG0798	PFAM Bile acid sodium symporter
GPX86_RS00560	COG0798	PFAM Bile acid sodium symporter
GPX86_RS00570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPX86_RS00575	COG0581	inorganic phosphate transmembrane transporter activity
GPX86_RS00580	COG0573	inorganic phosphate transmembrane transporter activity
GPX86_RS00590	COG0640	Transcriptional regulator
GPX86_RS00595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPX86_RS00625	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPX86_RS00630	COG3273	potassium ion transport
GPX86_RS00630	COG2985	domain, Protein
GPX86_RS00635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPX86_RS00640	COG1454	alcohol dehydrogenase
GPX86_RS00640	COG1012	belongs to the aldehyde dehydrogenase family
GPX86_RS00645	COG1737	Transcriptional regulator
GPX86_RS00650	COG0076	glutamate decarboxylase activity
GPX86_RS00655	COG2431	L-lysine efflux transmembrane transporter activity
GPX86_RS00665	COG3070	regulator of competence-specific genes
GPX86_RS00680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX86_RS00680	COG4191	Histidine kinase
GPX86_RS00680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX86_RS00680	COG4191	Histidine kinase
GPX86_RS00690	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPX86_RS00700	COG1032	radical SAM domain protein
GPX86_RS00710	COG0612	Peptidase, M16
GPX86_RS00725	COG0583	DNA-binding transcription factor activity
GPX86_RS00730	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPX86_RS00735	COG0501	Belongs to the peptidase M48B family
GPX86_RS00745	COG1028	Short-chain dehydrogenase reductase Sdr
GPX86_RS00760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GPX86_RS00780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPX86_RS00785	COG2915	High frequency lysogenization protein hflD homolog
GPX86_RS00790	COG0482	sulfurtransferase activity
GPX86_RS00795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPX86_RS00800	COG2916	Histone family protein nucleoid-structuring protein H-NS
GPX86_RS00805	COG1757	Na H antiporter
GPX86_RS00810	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GPX86_RS00815	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPX86_RS00820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPX86_RS00825	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPX86_RS00825	COG0131	Imidazoleglycerol-phosphate dehydratase
GPX86_RS00830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPX86_RS00835	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPX86_RS00840	COG0107	imidazoleglycerol-phosphate synthase activity
GPX86_RS00845	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GPX86_RS00845	COG0140	phosphoribosyl-ATP diphosphatase activity
GPX86_RS00850	COG1187	pseudouridine synthase activity
GPX86_RS00860	COG1278	Cold shock
GPX86_RS00865	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GPX86_RS00870	COG0542	response to heat
GPX86_RS00875	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPX86_RS00880	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GPX86_RS00885	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GPX86_RS00890	COG3134	Outer membrane lipoprotein
GPX86_RS00895	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GPX86_RS00905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPX86_RS00910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPX86_RS00915	COG0297	glycogen (starch) synthase activity
GPX86_RS00925	COG3070	regulator of competence-specific genes
GPX86_RS00930	COG1609	Transcriptional regulator
GPX86_RS00935	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPX86_RS00940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPX86_RS00950	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GPX86_RS00955	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GPX86_RS00965	COG0189	ligase activity
GPX86_RS00975	COG0189	ligase activity
GPX86_RS00975	COG4067	protein conserved in archaea
GPX86_RS00980	COG0500	methyltransferase
GPX86_RS00985	COG4106	trans-aconitate 2-methyltransferase activity
GPX86_RS00990	COG1801	Protein of unknown function DUF72
GPX86_RS01000	COG1435	thymidine kinase activity
GPX86_RS01005	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPX86_RS01020	COG2116	formate transmembrane transporter activity
GPX86_RS01030	COG4172	Belongs to the ABC transporter superfamily
GPX86_RS01040	COG4171	peptide transport system, permease
GPX86_RS01045	COG4168	peptide transport system, permease
GPX86_RS01055	COG2818	Glycosylase
GPX86_RS01060	COG0626	cystathionine gamma-synthase activity
GPX86_RS01070	COG0733	neurotransmitter:sodium symporter activity
GPX86_RS01075	COG0564	pseudouridine synthase activity
GPX86_RS01080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPX86_RS01085	COG4136	ATPase activity
GPX86_RS01090	COG4135	transport system, permease component
GPX86_RS01095	COG4134	Bacterial extracellular solute-binding protein
GPX86_RS01105	COG3313	Fe-S protein
GPX86_RS01115	COG0814	amino acid
GPX86_RS01135	COG2988	succinylglutamate desuccinylase activity
GPX86_RS01140	COG4139	cobalamin transport
GPX86_RS01145	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GPX86_RS01155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPX86_RS01160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPX86_RS01185	COG0583	DNA-binding transcription factor activity
GPX86_RS01195	COG1451	nucleotide metabolic process
GPX86_RS01210	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GPX86_RS01225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPX86_RS01240	COG0835	chemotaxis
GPX86_RS01240	COG0784	Response regulator, receiver
GPX86_RS01270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPX86_RS01285	COG0444	Belongs to the ABC transporter superfamily
GPX86_RS01295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPX86_RS01305	COG3290	protein histidine kinase activity
GPX86_RS01310	COG1518	maintenance of DNA repeat elements
GPX86_RS01315	COG1203	CRISPR-associated helicase, Cas3
GPX86_RS01335	COG3345	alpha-galactosidase
GPX86_RS01350	COG2205	protein histidine kinase activity
GPX86_RS01355	COG0745	RESPONSE REGULATOR receiver
GPX86_RS01375	COG0415	Belongs to the DNA photolyase family
GPX86_RS01380	COG1271	oxidase subunit
GPX86_RS01385	COG1294	oxidase, subunit
GPX86_RS01390	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPX86_RS01395	COG1254	Belongs to the acylphosphatase family
GPX86_RS01400	COG2920	part of a sulfur-relay system
GPX86_RS01405	COG0670	Belongs to the BI1 family
GPX86_RS01410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX86_RS01420	COG0561	phosphatase activity
GPX86_RS01425	COG0602	queuosine metabolic process
GPX86_RS01430	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPX86_RS01445	COG1132	(ABC) transporter
GPX86_RS01450	COG1132	(ABC) transporter
GPX86_RS01465	COG5002	protein histidine kinase activity
GPX86_RS01470	COG0443	Heat shock 70 kDa protein
GPX86_RS01475	COG0443	Heat shock 70 kDa protein
GPX86_RS01490	COG0840	transmembrane signaling receptor activity
GPX86_RS01505	COG1643	Atp-dependent helicase
GPX86_RS01515	COG0583	DNA-binding transcription factor activity
GPX86_RS01520	COG2814	Major facilitator Superfamily
GPX86_RS01530	COG2200	EAL domain
GPX86_RS01540	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GPX86_RS01550	COG0625	glutathione transferase activity
GPX86_RS01560	COG0395	ABC-type sugar transport system, permease component
GPX86_RS01565	COG1175	transmembrane transport
GPX86_RS01580	COG0840	transmembrane signaling receptor activity
GPX86_RS01585	COG0745	RESPONSE REGULATOR receiver
GPX86_RS01595	COG2198	Histidine kinase
GPX86_RS01595	COG0643	Histidine kinase
GPX86_RS01600	COG0840	transmembrane signaling receptor activity
GPX86_RS01600	COG0840	transmembrane signaling receptor activity
GPX86_RS01605	COG0835	chemotaxis
GPX86_RS01615	COG2201	protein-glutamate methylesterase activity
GPX86_RS01625	COG0811	peptide transport
GPX86_RS01630	COG0811	peptide transport
GPX86_RS01635	COG0848	biopolymer transport protein
GPX86_RS01660	COG0534	Mate efflux family protein
GPX86_RS01665	COG0307	riboflavin synthase, alpha
GPX86_RS01675	COG3437	response regulator, receiver
GPX86_RS01675	COG0784	Response regulator, receiver
GPX86_RS01690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX86_RS01690	COG4191	Histidine kinase
GPX86_RS01695	COG0393	Putative heavy-metal-binding
GPX86_RS01710	COG0791	NLP P60 protein
GPX86_RS01735	COG0303	'Molybdopterin
GPX86_RS01740	COG0746	molybdenum cofactor guanylyltransferase activity
GPX86_RS01750	COG4662	Binding-protein-dependent transport system inner membrane component
GPX86_RS01760	COG2204	response regulator
GPX86_RS01765	COG4191	Histidine kinase
GPX86_RS01770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPX86_RS01800	COG3383	formate dehydrogenase (NAD+) activity
GPX86_RS01800	COG0243	molybdopterin cofactor binding
GPX86_RS01805	COG0437	4 iron, 4 sulfur cluster binding
GPX86_RS01825	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPX86_RS01830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPX86_RS01835	COG1177	transmembrane transport
GPX86_RS01840	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPX86_RS01845	COG3842	ATPase activity
GPX86_RS01865	COG0589	response to stress
GPX86_RS01870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPX86_RS01885	COG2205	protein histidine kinase activity
GPX86_RS01885	COG0784	Response regulator, receiver
GPX86_RS01895	COG3120	sequence-specific DNA binding
GPX86_RS01900	COG1067	ATP-dependent peptidase activity
GPX86_RS01905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPX86_RS01920	COG0488	(ABC) transporter
GPX86_RS01925	COG0116	Belongs to the methyltransferase superfamily
GPX86_RS01925	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPX86_RS01935	COG0167	dihydroorotate dehydrogenase activity
GPX86_RS01940	COG2902	Dehydrogenase
GPX86_RS01950	COG0308	aminopeptidase N
GPX86_RS01965	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GPX86_RS01970	COG1956	GAF domain-containing protein
GPX86_RS01975	COG1132	(ABC) transporter
GPX86_RS01980	COG2995	paraquat-inducible protein a
GPX86_RS01985	COG3008	intermembrane lipid transfer
GPX86_RS01990	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GPX86_RS01990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPX86_RS01995	COG2996	Protein conserved in bacteria
GPX86_RS02015	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPX86_RS02030	COG1115	amino acid carrier protein
GPX86_RS02035	COG1280	lysine exporter protein (LysE YggA)
GPX86_RS02040	COG0003	Pfam Anion-transporting ATPase
GPX86_RS02050	COG1966	Carbon starvation protein
GPX86_RS02055	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GPX86_RS02060	COG2171	N-acyltransferase activity
GPX86_RS02095	COG3158	transport of potassium into the cell
GPX86_RS02100	COG2828	Protein conserved in bacteria
GPX86_RS02110	COG0372	Belongs to the citrate synthase family
GPX86_RS02115	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPX86_RS02140	COG4191	Histidine kinase
GPX86_RS02140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX86_RS02145	COG0471	metal ion transport
GPX86_RS02155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPX86_RS02160	COG5006	permease, DMT superfamily
GPX86_RS02170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPX86_RS02175	COG3283	Transcriptional regulator of aromatic amino acids metabolism
GPX86_RS02180	COG3768	UPF0283 membrane protein
GPX86_RS02185	COG3106	COG3106 Predicted ATPase
GPX86_RS02200	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPX86_RS02205	COG0494	nUDIX hydrolase
GPX86_RS02210	COG0814	amino acid
GPX86_RS02215	COG1760	l-serine dehydratase
GPX86_RS02220	COG0720	synthase
GPX86_RS02225	COG0017	Asparaginyl-tRNA synthetase
GPX86_RS02230	COG1448	Aminotransferase
GPX86_RS02240	COG0517	IMP dehydrogenase activity
GPX86_RS02245	COG2176	DNA-directed DNA polymerase activity
GPX86_RS02250	COG0840	transmembrane signaling receptor activity
GPX86_RS02255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPX86_RS02260	COG1846	Transcriptional regulator
GPX86_RS02275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPX86_RS02280	COG2989	Protein conserved in bacteria
GPX86_RS02285	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPX86_RS02300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPX86_RS02305	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPX86_RS02340	COG0019	diaminopimelate decarboxylase activity
GPX86_RS02345	COG1748	Saccharopine dehydrogenase
GPX86_RS02355	COG1320	monovalent cation:proton antiporter activity
GPX86_RS02360	COG2212	antiporter activity
GPX86_RS02365	COG1863	multisubunit Na H antiporter MnhE subunit
GPX86_RS02380	COG2111	Na H antiporter
GPX86_RS02390	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPX86_RS02405	COG4181	ATPase activity
GPX86_RS02410	COG0534	Mate efflux family protein
GPX86_RS02415	COG0702	epimerase
GPX86_RS02420	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPX86_RS02425	COG5380	lipid catabolic process
GPX86_RS02435	COG2814	Major facilitator Superfamily
GPX86_RS02440	COG1187	pseudouridine synthase activity
GPX86_RS02445	COG1061	Type III restriction enzyme res subunit
GPX86_RS02450	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GPX86_RS02470	COG0583	DNA-binding transcription factor activity
GPX86_RS02475	COG1840	ABC-type Fe3 transport system, periplasmic component
GPX86_RS02480	COG3842	ATPase activity
GPX86_RS02485	COG1178	ABC-type Fe3 transport system permease component
GPX86_RS02490	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GPX86_RS02495	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GPX86_RS02500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPX86_RS02510	COG0583	DNA-binding transcription factor activity
GPX86_RS02535	COG3527	Alpha-acetolactate decarboxylase
GPX86_RS02550	COG2925	Exonuclease
GPX86_RS02560	COG1346	cytolysis
GPX86_RS02565	COG0295	cytidine deaminase activity
GPX86_RS02570	COG5001	Diguanylate cyclase
GPX86_RS02575	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GPX86_RS02605	COG1943	Transposase
GPX86_RS02610	COG0072	phenylalanine-tRNA ligase activity
GPX86_RS02610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPX86_RS02655	COG0322	excinuclease ABC activity
GPX86_RS02660	COG2197	response regulator
GPX86_RS02680	COG0814	amino acid
GPX86_RS02690	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPX86_RS02695	COG3099	Belongs to the UPF0263 family
GPX86_RS02710	COG1228	amidohydrolase
GPX86_RS02715	COG0010	Belongs to the arginase family
GPX86_RS02725	COG2986	histidine ammonia-lyase
GPX86_RS02740	COG0415	Belongs to the DNA photolyase family
GPX86_RS02760	COG0277	FAD linked oxidase domain protein
GPX86_RS02760	COG0247	lactate metabolic process
GPX86_RS02775	COG2885	chlorophyll binding
GPX86_RS02790	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GPX86_RS02800	COG0281	malic enzyme
GPX86_RS02810	COG2949	membrane
GPX86_RS02820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPX86_RS02840	COG0492	ferredoxin-NADP+ reductase activity
GPX86_RS02845	COG4988	ABC transporter
GPX86_RS02850	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GPX86_RS02860	COG1187	pseudouridine synthase activity
GPX86_RS02865	COG0009	L-threonylcarbamoyladenylate synthase
GPX86_RS02870	COG0613	PHP domain protein
GPX86_RS02880	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPX86_RS02885	COG0512	Glutamine amidotransferase of anthranilate synthase
GPX86_RS02890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPX86_RS02895	COG0135	phosphoribosylanthranilate isomerase activity
GPX86_RS02895	COG0134	indole-3-glycerol-phosphate synthase activity
GPX86_RS02900	COG0133	tryptophan synthase activity
GPX86_RS02910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPX86_RS02920	COG1607	acyl-coa hydrolase
GPX86_RS02925	COG2350	Protein conserved in bacteria
GPX86_RS02935	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GPX86_RS02940	COG2226	methyltransferase
GPX86_RS02945	COG0156	8-amino-7-oxononanoate synthase activity
GPX86_RS02950	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPX86_RS02975	COG4771	TonB-dependent receptor
GPX86_RS02980	COG1770	oligopeptidase
GPX86_RS02985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPX86_RS02990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GPX86_RS02995	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GPX86_RS03000	COG0653	protein targeting
GPX86_RS03010	COG3092	negative regulation of chromosome organization
GPX86_RS03015	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPX86_RS03020	COG0857	belongs to the CobB CobQ family
GPX86_RS03020	COG0280	phosphate acetyltransferase
GPX86_RS03025	COG0435	Glutathione S-transferase
GPX86_RS03085	COG4964	Belongs to the GSP D family
GPX86_RS03110	COG0444	Belongs to the ABC transporter superfamily
GPX86_RS03115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPX86_RS03120	COG0601	transmembrane transport
GPX86_RS03135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPX86_RS03140	COG1621	beta-fructofuranosidase activity
GPX86_RS03150	COG1263	PTS System
GPX86_RS03150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX86_RS03160	COG2723	6-phospho-beta-galactosidase activity
GPX86_RS03165	COG1609	Transcriptional regulator
GPX86_RS03180	COG0366	Alpha amylase catalytic
GPX86_RS03185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPX86_RS03190	COG0646	methionine synthase
GPX86_RS03190	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPX86_RS03215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPX86_RS03240	COG0366	Alpha amylase catalytic
GPX86_RS03245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPX86_RS03250	COG0569	domain protein
GPX86_RS03260	COG2205	protein histidine kinase activity
GPX86_RS03265	COG0488	(ABC) transporter
GPX86_RS03270	COG2814	Major facilitator Superfamily
GPX86_RS03280	COG0318	PFAM AMP-dependent synthetase and ligase
GPX86_RS03285	COG0385	Bile acid
GPX86_RS03290	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPX86_RS03360	COG1946	Acyl-CoA thioesterase
GPX86_RS03365	COG1522	sequence-specific DNA binding
GPX86_RS03375	COG3015	lipoprotein NlpE involved in copper resistance
GPX86_RS03405	COG1441	menaquinone biosynthetic process
GPX86_RS03420	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GPX86_RS03425	COG1169	isochorismate synthase
GPX86_RS03430	COG0436	Aminotransferase
GPX86_RS03435	COG0583	DNA-binding transcription factor activity
GPX86_RS03440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPX86_RS03465	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GPX86_RS03470	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GPX86_RS03485	COG0616	signal peptide processing
GPX86_RS03490	COG1028	Short-chain dehydrogenase reductase Sdr
GPX86_RS03495	COG0784	Response regulator, receiver
GPX86_RS03495	COG0835	chemotaxis
GPX86_RS03500	COG1940	carbohydrate kinase activity
GPX86_RS03505	COG0469	pyruvate kinase activity
GPX86_RS03510	COG4667	esterase of the alpha-beta hydrolase superfamily
GPX86_RS03525	COG0733	neurotransmitter:sodium symporter activity
GPX86_RS03540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX86_RS03540	COG1263	PTS System
GPX86_RS03545	COG0084	hydrolase, TatD family'
GPX86_RS03555	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPX86_RS03560	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPX86_RS03565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPX86_RS03570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPX86_RS03575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPX86_RS03585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GPX86_RS03590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPX86_RS03595	COG0416	fatty acid biosynthetic process
GPX86_RS03605	COG1399	metal-binding, possibly nucleic acid-binding protein
GPX86_RS03610	COG0424	maF-like protein
GPX86_RS03615	COG0564	pseudouridine synthase activity
GPX86_RS03620	COG1530	ribonuclease E activity
GPX86_RS03655	COG0537	adenosine 5'-monophosphoramidase activity
GPX86_RS03660	COG0840	transmembrane signaling receptor activity
GPX86_RS03670	COG2186	Transcriptional regulator
GPX86_RS03675	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPX86_RS03680	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GPX86_RS03690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GPX86_RS03695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPX86_RS03700	COG1845	cytochrome c oxidase, subunit III
GPX86_RS03705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GPX86_RS03710	COG0109	protoheme IX farnesyltransferase activity
GPX86_RS03730	COG1674	ftsk spoiiie
GPX86_RS03735	COG1522	sequence-specific DNA binding
GPX86_RS03740	COG0686	Belongs to the AlaDH PNT family
GPX86_RS03765	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GPX86_RS03770	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GPX86_RS03780	COG0539	negative regulation of cytoplasmic translation
GPX86_RS03785	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GPX86_RS03795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPX86_RS03800	COG0776	regulation of translation
GPX86_RS03805	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPX86_RS03810	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPX86_RS03820	COG0544	peptidyl-prolyl cis-trans isomerase activity
GPX86_RS03825	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GPX86_RS03830	COG1760	l-serine dehydratase
GPX86_RS03840	COG3153	acetyltransferase
GPX86_RS03840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPX86_RS03860	COG2200	EAL domain
GPX86_RS03865	COG0840	transmembrane signaling receptor activity
GPX86_RS03875	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPX86_RS03880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPX86_RS03885	COG0583	DNA-binding transcription factor activity
GPX86_RS03890	COG2198	Histidine kinase
GPX86_RS03895	COG2204	response regulator
GPX86_RS03910	COG1301	dicarboxylic acid transport
GPX86_RS03920	COG3118	belongs to the thioredoxin family
GPX86_RS03925	COG4232	protein-disulfide reductase activity
GPX86_RS03935	COG4657	Part of a membrane complex involved in electron transport
GPX86_RS03940	COG2878	Part of a membrane complex involved in electron transport
GPX86_RS03945	COG4656	Part of a membrane complex involved in electron transport
GPX86_RS03950	COG4658	electron transport chain
GPX86_RS03955	COG4659	FMN binding
GPX86_RS03960	COG4660	Part of a membrane complex involved in electron transport
GPX86_RS03965	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPX86_RS03970	COG0346	lactoylglutathione lyase activity
GPX86_RS03985	COG2056	Na+-H+ antiporter family
GPX86_RS03990	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPX86_RS03995	COG1286	toxin biosynthetic process
GPX86_RS04000	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GPX86_RS04005	COG0285	dihydrofolate synthase activity
GPX86_RS04010	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPX86_RS04015	COG0101	tRNA pseudouridine synthase activity
GPX86_RS04025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPX86_RS04030	COG2190	(PTS) system
GPX86_RS04030	COG1263	PTS System
GPX86_RS04030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX86_RS04035	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPX86_RS04040	COG1940	carbohydrate kinase activity
GPX86_RS04040	COG1846	Transcriptional regulator
GPX86_RS04045	COG0367	asparagine synthase
GPX86_RS04050	COG0250	Participates in transcription elongation, termination and antitermination
GPX86_RS04055	COG3104	oligopeptide transport
GPX86_RS04060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GPX86_RS04065	COG0563	adenylate kinase activity
GPX86_RS04070	COG0326	Molecular chaperone. Has ATPase activity
GPX86_RS04075	COG3710	Transcriptional regulator
GPX86_RS04090	COG0622	Phosphoesterase
GPX86_RS04095	COG1090	epimerase
GPX86_RS04100	COG0300	oxidoreductase activity
GPX86_RS04105	COG3118	belongs to the thioredoxin family
GPX86_RS04110	COG0330	HflC and HflK could
GPX86_RS04115	COG1585	Membrane protein implicated in regulation of membrane protease activity
GPX86_RS04120	COG0789	Transcriptional regulator
GPX86_RS04135	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPX86_RS04140	COG3115	cell septum assembly
GPX86_RS04145	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GPX86_RS04150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPX86_RS04160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX86_RS04170	COG2190	(PTS) system
GPX86_RS04175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPX86_RS04180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPX86_RS04185	COG1702	phosphate starvation-inducible protein PhoH
GPX86_RS04190	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPX86_RS04195	COG4535	Mg2 and Co2 transporter CorC
GPX86_RS04200	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GPX86_RS04205	COG2888	peptidyl-tyrosine sulfation
GPX86_RS04210	COG0495	leucyl-tRNA aminoacylation
GPX86_RS04215	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GPX86_RS04220	COG1466	dna polymerase III delta subunit
GPX86_RS04225	COG0799	negative regulation of ribosome biogenesis
GPX86_RS04230	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPX86_RS04235	COG0768	penicillin binding
GPX86_RS04245	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPX86_RS04250	COG1686	Belongs to the peptidase S11 family
GPX86_RS04255	COG2921	Belongs to the UPF0250 family
GPX86_RS04270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPX86_RS04280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPX86_RS04310	COG0366	Alpha amylase catalytic
GPX86_RS04315	COG1263	PTS System
GPX86_RS04315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX86_RS04320	COG1609	Transcriptional regulator
GPX86_RS04325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPX86_RS04330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPX86_RS04335	COG2011	ABC-type metal ion transport system permease component
GPX86_RS04340	COG1464	Belongs to the NlpA lipoprotein family
GPX86_RS04345	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GPX86_RS04355	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPX86_RS04355	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPX86_RS04365	COG3706	GGDEF domain
GPX86_RS04365	COG0745	RESPONSE REGULATOR receiver
GPX86_RS04370	COG1611	Belongs to the LOG family
GPX86_RS04375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPX86_RS04385	COG2363	Small membrane protein
GPX86_RS04395	COG0583	DNA-binding transcription factor activity
GPX86_RS04400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPX86_RS04400	COG0301	tRNA thio-modification
GPX86_RS04410	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPX86_RS04415	COG1722	exodeoxyribonuclease VII activity
GPX86_RS04420	COG0142	geranyltranstransferase activity
GPX86_RS04425	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPX86_RS04430	COG0564	pseudouridine synthase activity
GPX86_RS04435	COG3098	single-species biofilm formation
GPX86_RS04460	COG1671	Belongs to the UPF0178 family
GPX86_RS04465	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPX86_RS04470	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GPX86_RS04480	COG1720	tRNA m6t6A37 methyltransferase activity
GPX86_RS04485	COG0442	prolyl-tRNA aminoacylation
GPX86_RS04505	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPX86_RS04505	COG0047	phosphoribosylformylglycinamidine synthase activity
GPX86_RS04510	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GPX86_RS04515	COG0590	tRNA wobble adenosine to inosine editing
GPX86_RS04520	COG0583	DNA-binding transcription factor activity
GPX86_RS04530	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GPX86_RS04535	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPX86_RS04570	COG0513	Belongs to the DEAD box helicase family
GPX86_RS04575	COG0484	heat shock protein binding
GPX86_RS04580	COG0443	Heat shock 70 kDa protein
GPX86_RS04585	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPX86_RS04590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPX86_RS04595	COG0497	DNA recombination
GPX86_RS04600	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPX86_RS04605	COG2914	Belongs to the UPF0125 (RnfH) family
GPX86_RS04610	COG2867	negative regulation of translational initiation
GPX86_RS04650	COG1464	Belongs to the NlpA lipoprotein family
GPX86_RS04665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPX86_RS04670	COG0840	transmembrane signaling receptor activity
GPX86_RS04695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GPX86_RS04735	COG1204	response to ionizing radiation
GPX86_RS04755	COG1609	Transcriptional regulator
GPX86_RS04755	COG2207	Transcriptional regulator
GPX86_RS04770	COG2239	Acts as a magnesium transporter
GPX86_RS04780	COG2239	Acts as a magnesium transporter
GPX86_RS04795	COG0583	DNA-binding transcription factor activity
GPX86_RS04800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPX86_RS04805	COG1115	amino acid carrier protein
GPX86_RS04820	COG1584	GPR1 FUN34 yaaH family protein
GPX86_RS04825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPX86_RS04840	COG0667	Aldo Keto reductase
GPX86_RS04855	COG0516	GMP reductase activity
GPX86_RS04855	COG0517	IMP dehydrogenase activity
GPX86_RS04860	COG1570	exodeoxyribonuclease VII activity
GPX86_RS04870	COG1160	GTP binding
GPX86_RS04875	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPX86_RS04880	COG2976	Protein conserved in bacteria
GPX86_RS04885	COG0124	histidyl-tRNA synthetase
GPX86_RS04890	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GPX86_RS04895	COG1426	Protein conserved in bacteria
GPX86_RS04905	COG0105	UTP biosynthetic process
GPX86_RS04910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPX86_RS04915	COG1104	cysteine desulfurase activity
GPX86_RS04920	COG1959	2 iron, 2 sulfur cluster binding
GPX86_RS04925	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GPX86_RS04930	COG0483	inositol monophosphate 1-phosphatase activity
GPX86_RS04935	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPX86_RS04940	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPX86_RS04945	COG1862	Preprotein translocase
GPX86_RS04955	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPX86_RS04960	COG0517	IMP dehydrogenase activity
GPX86_RS04970	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GPX86_RS04975	COG0583	DNA-binding transcription factor activity
GPX86_RS04980	COG0450	alkyl hydroperoxide reductase
GPX86_RS04990	COG0704	Plays a role in the regulation of phosphate uptake
GPX86_RS04995	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPX86_RS05000	COG0581	inorganic phosphate transmembrane transporter activity
GPX86_RS05005	COG0573	inorganic phosphate transmembrane transporter activity
GPX86_RS05010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GPX86_RS05015	COG0248	Ppx GppA phosphatase
GPX86_RS05025	COG5002	protein histidine kinase activity
GPX86_RS05030	COG0745	RESPONSE REGULATOR receiver
GPX86_RS05045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPX86_RS05065	COG1595	DNA-templated transcription, initiation
GPX86_RS05075	COG3248	Nucleoside-binding outer membrane protein
GPX86_RS05080	COG0737	Belongs to the 5'-nucleotidase family
GPX86_RS05085	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPX86_RS05090	COG0693	protein deglycase activity
GPX86_RS05095	COG2166	iron-sulfur cluster assembly
GPX86_RS05100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GPX86_RS05105	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GPX86_RS05115	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPX86_RS05115	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPX86_RS05120	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GPX86_RS05125	COG1074	ATP-dependent DNA helicase activity
GPX86_RS05130	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GPX86_RS05140	COG0583	DNA-binding transcription factor activity
GPX86_RS05145	COG3141	response to X-ray
GPX86_RS05150	COG2171	N-acyltransferase activity
GPX86_RS05160	COG0189	ligase activity
GPX86_RS05160	COG0569	domain protein
GPX86_RS05175	COG2059	Chromate
GPX86_RS05185	COG1022	Amp-dependent synthetase and ligase
GPX86_RS05190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPX86_RS05195	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPX86_RS05205	COG0560	Phosphoserine phosphatase
GPX86_RS05215	COG0813	purine-nucleoside phosphorylase activity
GPX86_RS05220	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPX86_RS05225	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GPX86_RS05230	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPX86_RS05235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPX86_RS05240	COG0084	hydrolase, TatD family'
GPX86_RS05250	COG3022	response to hydroperoxide
GPX86_RS05255	COG1115	amino acid carrier protein
GPX86_RS05270	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPX86_RS05275	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GPX86_RS05285	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPX86_RS05290	COG0083	homoserine kinase activity
GPX86_RS05305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPX86_RS05315	COG0745	RESPONSE REGULATOR receiver
GPX86_RS05325	COG5002	protein histidine kinase activity
GPX86_RS05325	COG0784	Response regulator, receiver
GPX86_RS05325	COG2198	Histidine kinase
GPX86_RS05330	COG1242	4 iron, 4 sulfur cluster binding
GPX86_RS05335	COG0070	glutamate synthase
GPX86_RS05335	COG0069	glutamate synthase activity
GPX86_RS05335	COG0067	glutamate synthase
GPX86_RS05350	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPX86_RS05360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPX86_RS05365	COG2860	membrane
GPX86_RS05370	COG0583	DNA-binding transcription factor activity
GPX86_RS05375	COG0730	response to heat
GPX86_RS05385	COG0505	Belongs to the CarA family
GPX86_RS05390	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GPX86_RS05395	COG0494	nUDIX hydrolase
GPX86_RS05400	COG0653	protein targeting
GPX86_RS05405	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GPX86_RS05410	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPX86_RS05415	COG0849	cell division
GPX86_RS05420	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GPX86_RS05425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPX86_RS05430	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPX86_RS05435	COG0772	Belongs to the SEDS family
GPX86_RS05440	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPX86_RS05450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GPX86_RS05455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPX86_RS05460	COG0768	penicillin binding
GPX86_RS05465	COG3116	cell division
GPX86_RS05470	COG0275	rRNA processing
GPX86_RS05480	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPX86_RS05485	COG3107	peptidoglycan biosynthetic process
GPX86_RS05490	COG0792	nuclease activity
GPX86_RS05495	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPX86_RS05500	COG2823	Periplasmic or secreted lipoprotein
GPX86_RS05505	COG2969	positive regulation of protein catabolic process
GPX86_RS05510	COG0625	glutathione transferase activity
GPX86_RS05515	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GPX86_RS05520	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPX86_RS05525	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GPX86_RS05535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPX86_RS05540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPX86_RS05545	COG0335	large ribosomal subunit rRNA binding
GPX86_RS05550	COG0336	Belongs to the RNA methyltransferase TrmD family
GPX86_RS05555	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPX86_RS05565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPX86_RS05570	COG4137	Cytochrome C assembly protein
GPX86_RS05575	COG4536	flavin adenine dinucleotide binding
GPX86_RS05580	COG1854	S-ribosylhomocysteine lyase activity
GPX86_RS05585	COG2918	glutathione biosynthetic process
GPX86_RS05590	COG0612	Peptidase, M16
GPX86_RS05595	COG1238	metal cluster binding
GPX86_RS05600	COG2130	NADP-dependent
GPX86_RS05605	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPX86_RS05610	COG5016	pyruvate
GPX86_RS05610	COG0511	ligase activity, forming carbon-carbon bonds
GPX86_RS05665	COG0527	aspartate kinase activity
GPX86_RS05670	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPX86_RS05680	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPX86_RS05685	COG1546	Belongs to the CinA family
GPX86_RS05690	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GPX86_RS05695	COG4208	sulfate ABC transporter
GPX86_RS05715	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPX86_RS05720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPX86_RS05725	COG1388	LysM domain
GPX86_RS05725	COG4942	peptidase
GPX86_RS05740	COG0585	pseudouridine synthase activity
GPX86_RS05745	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GPX86_RS05750	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPX86_RS05755	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GPX86_RS05765	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPX86_RS05770	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPX86_RS05775	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GPX86_RS05780	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPX86_RS05790	COG1610	YqeY-like protein
GPX86_RS05795	COG0358	DNA primase activity
GPX86_RS05800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPX86_RS05825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPX86_RS05830	COG3381	protein complex oligomerization
GPX86_RS05835	COG3302	dmso reductase anchor subunit
GPX86_RS05840	COG0437	4 iron, 4 sulfur cluster binding
GPX86_RS05845	COG0243	molybdopterin cofactor binding
GPX86_RS05850	COG2221	Nitrite and sulphite reductase 4Fe-4S
GPX86_RS05850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPX86_RS05855	COG0584	glycerophosphoryl diester phosphodiesterase
GPX86_RS05895	COG1349	DNA-binding transcription factor activity
GPX86_RS05900	COG0469	pyruvate kinase activity
GPX86_RS05905	COG3706	GGDEF domain
GPX86_RS05905	COG0745	RESPONSE REGULATOR receiver
GPX86_RS05925	COG0668	transmembrane transport
GPX86_RS05930	COG0191	fructose-bisphosphate aldolase activity
GPX86_RS05935	COG0126	phosphoglycerate kinase activity
GPX86_RS05940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPX86_RS05945	COG4771	TonB-dependent receptor
GPX86_RS05950	COG0583	DNA-binding transcription factor activity
GPX86_RS05955	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPX86_RS05965	COG3091	SprT-like family
GPX86_RS05970	COG2356	endonuclease I
GPX86_RS05975	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GPX86_RS05980	COG0189	ligase activity
GPX86_RS05985	COG1678	Uncharacterized ACR, COG1678
GPX86_RS05990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPX86_RS06005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPX86_RS06010	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPX86_RS06015	COG0762	integral membrane protein
GPX86_RS06020	COG1872	DUF167
GPX86_RS06025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPX86_RS06030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPX86_RS06040	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GPX86_RS06045	COG1194	a g-specific adenine glycosylase
GPX86_RS06050	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GPX86_RS06055	COG0741	lytic transglycosylase activity
GPX86_RS06105	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPX86_RS06110	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GPX86_RS06115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPX86_RS06120	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GPX86_RS06125	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GPX86_RS06130	COG2967	ApaG domain
GPX86_RS06150	COG2966	Psort location CytoplasmicMembrane, score
GPX86_RS06165	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GPX86_RS06170	COG0142	geranyltranstransferase activity
GPX86_RS06175	COG0531	amino acid
GPX86_RS06180	COG0039	L-malate dehydrogenase activity
GPX86_RS06200	COG0589	response to stress
GPX86_RS06220	COG0312	modulator of DNA gyrase
GPX86_RS06225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPX86_RS06230	COG3164	Protein of unknown function
GPX86_RS06235	COG1530	ribonuclease E activity
GPX86_RS06245	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GPX86_RS06250	COG1792	Involved in formation and maintenance of cell shape
GPX86_RS06255	COG1077	Cell shape determining protein MreB Mrl
GPX86_RS06295	COG1459	type II secretion system
GPX86_RS06300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPX86_RS06310	COG3409	Peptidoglycan-binding domain 1 protein
GPX86_RS06310	COG3267	Type II secretory pathway component ExeA
GPX86_RS06315	COG1450	Type ii and iii secretion system protein
GPX86_RS06335	COG2199	diguanylate cyclase activity
GPX86_RS06335	COG2200	EAL domain
GPX86_RS06340	COG0629	single-stranded DNA binding
GPX86_RS06355	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPX86_RS06365	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPX86_RS06370	COG0527	aspartate kinase activity
GPX86_RS06420	COG0175	sulfate reduction
GPX86_RS06445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPX86_RS06450	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPX86_RS06455	COG0735	belongs to the Fur family
GPX86_RS06465	COG0166	Belongs to the GPI family
GPX86_RS06470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPX86_RS06475	COG0305	Participates in initiation and elongation during chromosome replication
GPX86_RS06495	COG0360	Binds together with S18 to 16S ribosomal RNA
GPX86_RS06505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPX86_RS06510	COG0049	tRNA binding
GPX86_RS06520	COG2168	tRNA wobble position uridine thiolation
GPX86_RS06525	COG2923	Belongs to the DsrF TusC family
GPX86_RS06530	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GPX86_RS06535	COG2964	Protein conserved in bacteria
GPX86_RS06540	COG0545	Peptidyl-prolyl cis-trans isomerase
GPX86_RS06550	COG2900	Belongs to the SlyX family
GPX86_RS06555	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GPX86_RS06560	COG0330	HflC and HflK could
GPX86_RS06565	COG0330	HflC and HflK could
GPX86_RS06570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPX86_RS06580	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPX86_RS06585	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPX86_RS06590	COG0860	N-Acetylmuramoyl-L-alanine amidase
GPX86_RS06595	COG0802	atpase or kinase
GPX86_RS06600	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPX86_RS06655	COG1162	GTPase activity
GPX86_RS06660	COG0688	phosphatidylethanolamine metabolic process
GPX86_RS06665	COG0471	metal ion transport
GPX86_RS06670	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPX86_RS06675	COG0513	Belongs to the DEAD box helicase family
GPX86_RS06680	COG4942	peptidase
GPX86_RS06695	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GPX86_RS06700	COG2816	NAD+ diphosphatase activity
GPX86_RS06705	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GPX86_RS06710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPX86_RS06715	COG0085	RNA polymerase activity
GPX86_RS06725	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPX86_RS06735	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPX86_RS06745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPX86_RS06775	COG1072	(Pantothenic acid kinase))
GPX86_RS06785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GPX86_RS06795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPX86_RS06840	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GPX86_RS06845	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPX86_RS06850	COG3118	belongs to the thioredoxin family
GPX86_RS06855	COG0513	Belongs to the DEAD box helicase family
GPX86_RS06860	COG0248	Ppx GppA phosphatase
GPX86_RS06865	COG2198	Histidine kinase
GPX86_RS06865	COG0784	Response regulator, receiver
GPX86_RS06865	COG2205	protein histidine kinase activity
GPX86_RS06870	COG2814	Major facilitator Superfamily
GPX86_RS06885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPX86_RS06890	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GPX86_RS06895	COG0511	ligase activity, forming carbon-carbon bonds
GPX86_RS06900	COG0439	Biotin carboxylase
GPX86_RS06915	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GPX86_RS06920	COG0583	DNA-binding transcription factor activity
GPX86_RS06930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX86_RS06940	COG2207	Transcriptional regulator
GPX86_RS06945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX86_RS06945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX86_RS06945	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX86_RS06950	COG1482	cell wall glycoprotein biosynthetic process
GPX86_RS06955	COG0737	Belongs to the 5'-nucleotidase family
GPX86_RS06985	COG0776	regulation of translation
GPX86_RS06990	COG1253	flavin adenine dinucleotide binding
GPX86_RS06995	COG0668	transmembrane transport
GPX86_RS07000	COG3068	Protein conserved in bacteria
GPX86_RS07005	COG0840	transmembrane signaling receptor activity
GPX86_RS07015	COG2197	response regulator
GPX86_RS07025	COG2271	Major facilitator Superfamily
GPX86_RS07095	COG0438	transferase activity, transferring glycosyl groups
GPX86_RS07095	COG1216	Glycosyl transferase, family 2
GPX86_RS07100	COG0438	transferase activity, transferring glycosyl groups
GPX86_RS07100	COG1216	Glycosyl transferase, family 2
GPX86_RS07110	COG0463	Glycosyl transferase, family 2
GPX86_RS07130	COG1216	Glycosyl transferase, family 2
GPX86_RS07165	COG1216	Glycosyl transferase, family 2
GPX86_RS07210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPX86_RS07240	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GPX86_RS07265	COG1086	Polysaccharide biosynthesis protein
GPX86_RS07305	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GPX86_RS07320	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPX86_RS07335	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPX86_RS07340	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GPX86_RS07385	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPX86_RS07395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPX86_RS07415	COG1560	Kdo2-lipid A biosynthetic process
GPX86_RS07430	COG0438	transferase activity, transferring glycosyl groups
GPX86_RS07450	COG0859	PFAM glycosyl transferase family 9
GPX86_RS07455	COG1519	Transferase
GPX86_RS07460	COG3642	lipopolysaccharide core region biosynthetic process
GPX86_RS07465	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPX86_RS07470	COG0859	PFAM glycosyl transferase family 9
GPX86_RS07475	COG0438	transferase activity, transferring glycosyl groups
GPX86_RS07480	COG0463	Glycosyl transferase, family 2
GPX86_RS07485	COG0859	PFAM glycosyl transferase family 9
GPX86_RS07490	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPX86_RS07505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GPX86_RS07520	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPX86_RS07525	COG1309	transcriptional regulator
GPX86_RS07530	COG1560	Kdo2-lipid A biosynthetic process
GPX86_RS07535	COG3275	phosphorelay sensor kinase activity
GPX86_RS07540	COG3279	Response regulator of the LytR AlgR family
GPX86_RS07545	COG2223	nitrite transmembrane transporter activity
GPX86_RS07550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPX86_RS07560	COG1561	YicC-like family, N-terminal region
GPX86_RS07570	COG1120	ATPase activity
GPX86_RS07575	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPX86_RS07580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPX86_RS07590	COG4773	Receptor
GPX86_RS07605	COG3486	L-lysine 6-monooxygenase (NADPH) activity
GPX86_RS07610	COG0076	glutamate decarboxylase activity
GPX86_RS07625	COG1289	transmembrane transporter activity
GPX86_RS07630	COG1566	PFAM secretion protein HlyD family protein
GPX86_RS07640	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GPX86_RS07645	COG0612	Peptidase, M16
GPX86_RS07650	COG1228	amidohydrolase
GPX86_RS07660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPX86_RS07660	COG1263	PTS System
GPX86_RS07665	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPX86_RS07680	COG0514	ATP-dependent DNA helicase (RecQ)
GPX86_RS07685	COG2962	Rard protein
GPX86_RS07690	COG1280	lysine exporter protein (LysE YggA)
GPX86_RS07695	COG0210	DNA helicase
GPX86_RS07705	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GPX86_RS07710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPX86_RS07780	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPX86_RS07805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPX86_RS07815	COG0747	negative chemotaxis
GPX86_RS07820	COG4172	Belongs to the ABC transporter superfamily
GPX86_RS07855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPX86_RS07860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPX86_RS07865	COG2960	long-chain fatty acid transporting porin activity
GPX86_RS07875	COG0583	DNA-binding transcription factor activity
GPX86_RS07945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPX86_RS07950	COG1739	Uncharacterized protein family UPF0029
GPX86_RS07955	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPX86_RS07955	COG1024	Enoyl-CoA hydratase
GPX86_RS07960	COG0183	Belongs to the thiolase family
GPX86_RS07965	COG0583	DNA-binding transcription factor activity
GPX86_RS07970	COG2814	Major facilitator Superfamily
GPX86_RS07980	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GPX86_RS07990	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPX86_RS08005	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPX86_RS08015	COG0356	it plays a direct role in the translocation of protons across the membrane
GPX86_RS08020	COG3312	ion transport
GPX86_RS08025	COG1475	DNA binding
GPX86_RS08030	COG1192	Involved in chromosome partitioning
GPX86_RS08035	COG0357	Ribosomal RNA small subunit methyltransferase G
GPX86_RS08040	COG0445	tRNA wobble uridine modification
GPX86_RS08045	COG0071	Belongs to the small heat shock protein (HSP20) family
GPX86_RS08060	COG0187	DNA topoisomerase II activity
GPX86_RS08070	COG0592	DNA-directed DNA polymerase activity
GPX86_RS08075	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPX86_RS08080	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GPX86_RS08090	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GPX86_RS08095	COG0706	membrane insertase activity
GPX86_RS08100	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPX86_RS08105	COG0784	Response regulator, receiver
GPX86_RS08105	COG5002	protein histidine kinase activity
GPX86_RS08105	COG2198	Histidine kinase
GPX86_RS08110	COG5002	protein histidine kinase activity
GPX86_RS08115	COG0745	RESPONSE REGULATOR receiver
GPX86_RS08115	COG3706	GGDEF domain
GPX86_RS08125	COG0745	RESPONSE REGULATOR receiver
GPX86_RS08130	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPX86_RS08140	COG2922	Belongs to the Smg family
GPX86_RS08145	COG0758	DNA mediated transformation
GPX86_RS08155	COG0242	peptide deformylase activity
GPX86_RS08165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPX86_RS08165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPX86_RS08170	COG0569	domain protein
GPX86_RS08175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPX86_RS08180	COG1272	protein, Hemolysin III
GPX86_RS08190	COG3084	Protein conserved in bacteria
GPX86_RS08195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPX86_RS08200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPX86_RS08205	COG0606	chelatase, subunit chli
GPX86_RS08215	COG3978	acetolactate synthase activity
GPX86_RS08220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPX86_RS08225	COG0129	dihydroxy-acid dehydratase activity
GPX86_RS08235	COG0604	alcohol dehydrogenase
GPX86_RS08250	COG2119	membrane
GPX86_RS08255	COG0752	glycyl-tRNA synthetase alpha subunit
GPX86_RS08260	COG0751	glycine-tRNA ligase activity
GPX86_RS08265	COG3977	Valine--pyruvate aminotransferase
GPX86_RS08270	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPX86_RS08275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPX86_RS08280	COG0009	L-threonylcarbamoyladenylate synthase
GPX86_RS08290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPX86_RS08300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPX86_RS08345	COG0038	chloride channel
GPX86_RS08350	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GPX86_RS08360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPX86_RS08375	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPX86_RS08380	COG4175	Glycine betaine
GPX86_RS08410	COG0006	proline dipeptidase activity
GPX86_RS08410	COG0006	proline dipeptidase activity
GPX86_RS08430	COG1522	sequence-specific DNA binding
GPX86_RS08435	COG0742	ribosomal rna small subunit methyltransferase
GPX86_RS08445	COG0697	spore germination
GPX86_RS08455	COG1528	Iron-storage protein
GPX86_RS08465	COG2081	HI0933 family
GPX86_RS08475	COG1322	Protein conserved in bacteria
GPX86_RS08480	COG2226	methyltransferase
GPX86_RS08490	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GPX86_RS08495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPX86_RS08500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPX86_RS08505	COG0805	protein transport
GPX86_RS08510	COG0084	hydrolase, TatD family'
GPX86_RS08520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPX86_RS08520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPX86_RS08525	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GPX86_RS08545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPX86_RS08555	COG2959	enzyme of heme biosynthesis
GPX86_RS08560	COG1587	Uroporphyrinogen-III synthase
GPX86_RS08575	COG3072	Adenylate cyclase
GPX86_RS08585	COG0019	diaminopimelate decarboxylase activity
GPX86_RS08605	COG1011	Hydrolase
GPX86_RS08610	COG3287	FIST C domain
GPX86_RS08610	COG2200	EAL domain
GPX86_RS08610	COG2199	diguanylate cyclase activity
GPX86_RS08630	COG0561	phosphatase activity
GPX86_RS08635	COG2267	carboxylic ester hydrolase activity
GPX86_RS08640	COG0783	Belongs to the Dps family
GPX86_RS08665	COG2095	MarC family integral membrane protein
GPX86_RS08670	COG0742	ribosomal rna small subunit methyltransferase
GPX86_RS08675	COG0552	protein localization to endoplasmic reticulum
GPX86_RS08680	COG2884	Cell division ATP-binding protein ftsE
GPX86_RS08685	COG2177	Part of the ABC transporter FtsEX involved in
GPX86_RS08690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPX86_RS08695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPX86_RS08710	COG3161	chorismate lyase activity
GPX86_RS08720	COG2937	Belongs to the GPAT DAPAT family
GPX86_RS08725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPX86_RS08735	COG0534	Mate efflux family protein
GPX86_RS08740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPX86_RS08785	COG0328	RNA-DNA hybrid ribonuclease activity
GPX86_RS08800	COG2003	Belongs to the UPF0758 family
GPX86_RS08820	COG2003	Belongs to the UPF0758 family
GPX86_RS08825	COG0326	Molecular chaperone. Has ATPase activity
GPX86_RS08850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPX86_RS08860	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GPX86_RS08920	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPX86_RS08925	COG2204	response regulator
GPX86_RS08930	COG3852	Histidine kinase
GPX86_RS08940	COG0174	glutamine synthetase
GPX86_RS08955	COG1490	D-aminoacyl-tRNA deacylase activity
GPX86_RS08960	COG0456	acetyltransferase
GPX86_RS08970	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GPX86_RS08975	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPX86_RS08980	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GPX86_RS08985	COG3031	protein transport across the cell outer membrane
GPX86_RS08995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPX86_RS09000	COG1459	type II secretion system
GPX86_RS09005	COG2165	general secretion pathway protein
GPX86_RS09010	COG2165	general secretion pathway protein
GPX86_RS09015	COG2165	general secretion pathway protein
GPX86_RS09020	COG4795	General secretion pathway protein
GPX86_RS09025	COG3156	type II secretion system protein K
GPX86_RS09030	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPX86_RS09035	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPX86_RS09045	COG1218	3'(2'),5'-bisphosphate nucleotidase
GPX86_RS09050	COG0494	nUDIX hydrolase
GPX86_RS09055	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GPX86_RS09055	COG0316	Belongs to the HesB IscA family
GPX86_RS09065	COG0596	Alpha beta hydrolase
GPX86_RS09075	COG2183	response to ionizing radiation
GPX86_RS09080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPX86_RS09085	COG1609	Transcriptional regulator
GPX86_RS09090	COG0129	dihydroxy-acid dehydratase activity
GPX86_RS09095	COG3265	gluconokinase activity
GPX86_RS09100	COG2610	gluconate transmembrane transporter activity
GPX86_RS09105	COG0800	Aldolase
GPX86_RS09110	COG0745	RESPONSE REGULATOR receiver
GPX86_RS09115	COG2205	protein histidine kinase activity
GPX86_RS09120	COG2233	PERMEase
GPX86_RS09125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPX86_RS09130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPX86_RS09135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPX86_RS09140	COG1758	RNA polymerase activity
GPX86_RS09145	COG0194	GDP metabolic process
GPX86_RS09150	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPX86_RS09160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPX86_RS09170	COG3263	regulation of cellular component size
GPX86_RS09185	COG4232	protein-disulfide reductase activity
GPX86_RS09190	COG1438	arginine binding
GPX86_RS09195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPX86_RS09210	COG1288	antiporter activity
GPX86_RS09215	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPX86_RS09220	COG1027	Aspartate ammonia-lyase
GPX86_RS09225	COG3030	protein affecting phage T7 exclusion by the F plasmid
GPX86_RS09230	COG1278	Cold shock
GPX86_RS09235	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GPX86_RS09240	COG2205	protein histidine kinase activity
GPX86_RS09245	COG0745	RESPONSE REGULATOR receiver
GPX86_RS09255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPX86_RS09260	COG0205	6-phosphofructokinase activity
GPX86_RS09265	COG1494	fructose-1,6-bisphosphatase
GPX86_RS09275	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPX86_RS09280	COG0527	aspartate kinase activity
GPX86_RS09280	COG0460	homoserine dehydrogenase
GPX86_RS09285	COG0626	cystathionine gamma-synthase activity
GPX86_RS09295	COG0281	malic enzyme
GPX86_RS09305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPX86_RS09310	COG1609	Transcriptional regulator
GPX86_RS09320	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GPX86_RS09325	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GPX86_RS09330	COG1575	Belongs to the MenA family. Type 1 subfamily
GPX86_RS09335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPX86_RS09340	COG0534	Mate efflux family protein
GPX86_RS09370	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPX86_RS09375	COG0459	protein refolding
GPX86_RS09380	COG1285	pathogenesis
GPX86_RS09385	COG1509	lysine 2,3-aminomutase activity
GPX86_RS09390	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPX86_RS09395	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPX86_RS09400	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPX86_RS09405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPX86_RS09410	COG1053	succinate dehydrogenase
GPX86_RS09415	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GPX86_RS09420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPX86_RS09425	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GPX86_RS09430	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GPX86_RS09435	COG1045	serine acetyltransferase
GPX86_RS09445	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GPX86_RS09450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPX86_RS09455	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPX86_RS09460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPX86_RS09470	COG0165	Argininosuccinate lyase
GPX86_RS09470	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPX86_RS09485	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GPX86_RS09515	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GPX86_RS09520	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPX86_RS09530	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GPX86_RS09535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPX86_RS09540	COG0546	phosphoglycolate phosphatase activity
GPX86_RS09545	COG0180	Tryptophanyl-tRNA synthetase
GPX86_RS09555	COG0512	Glutamine amidotransferase of anthranilate synthase
GPX86_RS09560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPX86_RS09580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPX86_RS09585	COG3954	Phosphoribulokinase
GPX86_RS09595	COG0429	hydrolase of the alpha beta-hydrolase fold
GPX86_RS09605	COG0488	(ABC) transporter
GPX86_RS09610	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPX86_RS09625	COG1047	Peptidyl-prolyl cis-trans
GPX86_RS09630	COG1446	asparaginase
GPX86_RS09635	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPX86_RS09640	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GPX86_RS09645	COG0557	exoribonuclease II activity
GPX86_RS09650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPX86_RS09655	COG0051	transcription antitermination factor activity, RNA binding
GPX86_RS09660	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPX86_RS09665	COG0088	Forms part of the polypeptide exit tunnel
GPX86_RS09670	COG0089	rRNA binding
GPX86_RS09680	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPX86_RS09685	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPX86_RS09690	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPX86_RS09700	COG0255	Belongs to the universal ribosomal protein uL29 family
GPX86_RS09710	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPX86_RS09720	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPX86_RS09725	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPX86_RS09730	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPX86_RS09735	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPX86_RS09750	COG1841	ribosomal large subunit assembly
GPX86_RS09760	COG0201	protein transport
GPX86_RS09775	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPX86_RS09780	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPX86_RS09785	COG0202	RNA polymerase activity
GPX86_RS09790	COG0203	ribosomal protein L17
GPX86_RS09800	COG0545	Peptidyl-prolyl cis-trans isomerase
GPX86_RS09810	COG2153	protein acetylation
GPX86_RS09815	COG0513	Belongs to the DEAD box helicase family
GPX86_RS09830	COG1648	precorrin-2 dehydrogenase activity
GPX86_RS09830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPX86_RS09835	COG0175	sulfate reduction
GPX86_RS09840	COG2895	sulfate adenylyltransferase (ATP) activity
GPX86_RS09845	COG0529	Catalyzes the synthesis of activated sulfate
GPX86_RS09865	COG1136	(ABC) transporter
GPX86_RS09865	COG0577	efflux transmembrane transporter activity
GPX86_RS09880	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GPX86_RS09890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPX86_RS09895	COG0729	surface antigen
GPX86_RS09905	COG2105	PFAM AIG2 family protein
GPX86_RS09910	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GPX86_RS09915	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GPX86_RS09920	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPX86_RS09925	COG0163	prenyltransferase activity
GPX86_RS09935	COG1178	ABC-type Fe3 transport system permease component
GPX86_RS09945	COG3028	Belongs to the UPF0307 family
GPX86_RS09950	COG0312	modulator of DNA gyrase
GPX86_RS09955	COG2239	Acts as a magnesium transporter
GPX86_RS09960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX86_RS09970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX86_RS09975	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPX86_RS09985	COG1137	ATPase activity
GPX86_RS09990	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GPX86_RS10000	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GPX86_RS10005	COG0517	IMP dehydrogenase activity
GPX86_RS10005	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GPX86_RS10015	COG1127	ABC transporter
GPX86_RS10020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GPX86_RS10025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPX86_RS10030	COG2854	intermembrane phospholipid transfer
GPX86_RS10040	COG5007	Belongs to the BolA IbaG family
GPX86_RS10045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPX86_RS10050	COG0204	Acyl-transferase
GPX86_RS10055	COG0251	oxidation-reduction process
GPX86_RS10060	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GPX86_RS10065	COG0540	Belongs to the ATCase OTCase family
GPX86_RS10070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPX86_RS10075	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GPX86_RS10080	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GPX86_RS10090	COG0564	pseudouridine synthase activity
GPX86_RS10095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPX86_RS10100	COG0525	valine-tRNA ligase activity
GPX86_RS10105	COG2927	DNA polymerase III (CHI subunit)
GPX86_RS10115	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPX86_RS10120	COG0795	lipopolysaccharide-transporting ATPase activity
GPX86_RS10125	COG0795	lipopolysaccharide-transporting ATPase activity
GPX86_RS10185	COG0066	3-isopropylmalate dehydratase activity
GPX86_RS10190	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPX86_RS10195	COG0473	3-isopropylmalate dehydrogenase activity
GPX86_RS10200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPX86_RS10205	COG0671	phosphoesterase, PA-phosphatase related
GPX86_RS10215	COG0583	DNA-binding transcription factor activity
GPX86_RS10220	COG1022	Amp-dependent synthetase and ligase
GPX86_RS10225	COG0028	Belongs to the TPP enzyme family
GPX86_RS10235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPX86_RS10240	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GPX86_RS10245	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPX86_RS10255	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPX86_RS10265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPX86_RS10270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPX86_RS10285	COG0354	folic acid binding
GPX86_RS10300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GPX86_RS10305	COG1595	DNA-templated transcription, initiation
GPX86_RS10315	COG3026	antisigma factor binding
GPX86_RS10320	COG3086	response to oxidative stress
GPX86_RS10325	COG0481	GTPase activity
GPX86_RS10330	COG0681	Belongs to the peptidase S26 family
GPX86_RS10345	COG1381	Involved in DNA repair and RecF pathway recombination
GPX86_RS10350	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GPX86_RS10355	COG0736	holo-[acyl-carrier-protein] synthase activity
GPX86_RS10365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPX86_RS10370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPX86_RS10375	COG3956	TIGRFAM MazG family protein
GPX86_RS10380	COG0504	CTP synthase activity
GPX86_RS10390	COG0617	tRNA 3'-terminal CCA addition
GPX86_RS10395	COG4991	sh3 domain protein
GPX86_RS10400	COG0306	phosphate transporter
GPX86_RS10405	COG1392	Phosphate transport regulator
GPX86_RS10410	COG3025	triphosphatase activity
GPX86_RS10420	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GPX86_RS10430	COG1538	Outer membrane efflux protein
GPX86_RS10435	COG0494	nUDIX hydrolase
GPX86_RS10440	COG3151	Protein conserved in bacteria
GPX86_RS10450	COG3150	esterase
GPX86_RS10455	COG0187	DNA topoisomerase II activity
GPX86_RS10465	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GPX86_RS10470	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GPX86_RS10485	COG1459	type II secretion system
GPX86_RS10490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPX86_RS10500	COG0157	Belongs to the NadC ModD family
GPX86_RS10510	COG0716	FMN binding
GPX86_RS10520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPX86_RS10525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GPX86_RS10530	COG2186	Transcriptional regulator
GPX86_RS10535	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GPX86_RS10540	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPX86_RS10545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPX86_RS10565	COG0288	reversible hydration of carbon dioxide
GPX86_RS10570	COG1131	(ABC) transporter
GPX86_RS10575	COG0842	Transport permease protein
GPX86_RS10580	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GPX86_RS10585	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GPX86_RS10590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPX86_RS10600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPX86_RS10605	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPX86_RS10615	COG1643	Atp-dependent helicase
GPX86_RS10620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPX86_RS10625	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPX86_RS10630	COG1049	propionate catabolic process, 2-methylcitrate cycle
GPX86_RS10665	COG1121	(ABC) transporter
GPX86_RS10670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPX86_RS10680	COG0745	RESPONSE REGULATOR receiver
GPX86_RS10690	COG4771	TonB-dependent receptor
GPX86_RS10695	COG1929	Belongs to the glycerate kinase type-1 family
GPX86_RS10705	COG0347	Belongs to the P(II) protein family
GPX86_RS10710	COG0004	ammonium transporteR
GPX86_RS10715	COG3842	ATPase activity
GPX86_RS10725	COG1840	ABC-type Fe3 transport system, periplasmic component
GPX86_RS10730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPX86_RS10750	COG4608	Belongs to the ABC transporter superfamily
GPX86_RS10755	COG0444	Belongs to the ABC transporter superfamily
GPX86_RS10770	COG0747	negative chemotaxis
GPX86_RS10775	COG0784	Response regulator, receiver
GPX86_RS10775	COG2205	protein histidine kinase activity
GPX86_RS10775	COG2198	Histidine kinase
GPX86_RS10775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX86_RS10780	COG2813	Specifically methylates the guanine in position
GPX86_RS10785	COG0628	permease
GPX86_RS10790	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GPX86_RS10795	COG0316	Belongs to the HesB IscA family
GPX86_RS10800	COG0739	heme binding
GPX86_RS10805	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPX86_RS10810	COG2027	D-alanyl-D-alanine carboxypeptidase
GPX86_RS10815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPX86_RS10820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPX86_RS10825	COG1534	Rna-binding protein
GPX86_RS10835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPX86_RS10840	COG1943	Transposase
GPX86_RS10845	COG1943	Transposase
GPX86_RS10850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPX86_RS10855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPX86_RS10860	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPX86_RS10880	COG0195	Participates in both transcription termination and antitermination
GPX86_RS10885	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPX86_RS10890	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPX86_RS10895	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPX86_RS10900	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPX86_RS10905	COG1185	polyribonucleotide nucleotidyltransferase activity
GPX86_RS10935	COG3153	acetyltransferase
GPX86_RS10955	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GPX86_RS10960	COG0513	Belongs to the DEAD box helicase family
GPX86_RS10965	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GPX86_RS10980	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GPX86_RS10985	COG2204	response regulator
GPX86_RS10990	COG0667	Aldo Keto reductase
GPX86_RS10995	COG3066	DNA modification
GPX86_RS11000	COG0494	nUDIX hydrolase
GPX86_RS11010	COG0730	response to heat
GPX86_RS11020	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPX86_RS11025	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPX86_RS11030	COG0583	DNA-binding transcription factor activity
GPX86_RS11035	COG0640	Transcriptional regulator
GPX86_RS11045	COG0728	peptidoglycan biosynthetic process
GPX86_RS11050	COG0196	riboflavin kinase activity
GPX86_RS11055	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPX86_RS11060	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPX86_RS11065	COG1047	Peptidyl-prolyl cis-trans
GPX86_RS11070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GPX86_RS11075	COG1966	Carbon starvation protein
GPX86_RS11085	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GPX86_RS11095	COG3279	Response regulator of the LytR AlgR family
GPX86_RS11100	COG3275	phosphorelay sensor kinase activity
GPX86_RS11105	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPX86_RS11110	COG1605	Chorismate mutase
GPX86_RS11110	COG0287	Prephenate dehydrogenase
GPX86_RS11120	COG0488	(ABC) transporter
GPX86_RS11135	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GPX86_RS11140	COG0077	Prephenate dehydratase
GPX86_RS11140	COG1605	Chorismate mutase
GPX86_RS11145	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPX86_RS11150	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPX86_RS11155	COG0564	pseudouridine synthase activity
GPX86_RS11165	COG0542	response to heat
GPX86_RS11240	COG0271	Belongs to the BolA IbaG family
GPX86_RS11245	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPX86_RS11250	COG1805	sodium ion transport
GPX86_RS11255	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPX86_RS11260	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPX86_RS11265	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPX86_RS11275	COG1477	protein flavinylation
GPX86_RS11295	COG0733	neurotransmitter:sodium symporter activity
GPX86_RS11305	COG0189	ligase activity
GPX86_RS11310	COG0189	ligase activity
GPX86_RS11310	COG4067	protein conserved in archaea
GPX86_RS11315	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPX86_RS11320	COG2252	PERMEase
GPX86_RS11325	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GPX86_RS11340	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPX86_RS11345	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPX86_RS11350	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPX86_RS11355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPX86_RS11355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPX86_RS11375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPX86_RS11380	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GPX86_RS11385	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GPX86_RS11395	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GPX86_RS11400	COG0024	Methionine aminopeptidase
GPX86_RS11410	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPX86_RS11420	COG0233	cytoplasmic translational termination
GPX86_RS11425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPX86_RS11430	COG0575	Belongs to the CDS family
GPX86_RS11435	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GPX86_RS11440	COG0750	zinc metalloprotease
GPX86_RS11450	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GPX86_RS11455	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPX86_RS11460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPX86_RS11465	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPX86_RS11470	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPX86_RS11475	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPX86_RS11480	COG0587	DNA-directed DNA polymerase activity
GPX86_RS11485	COG0825	malonyl-CoA metabolic process
GPX86_RS11490	COG0037	tRNA processing
GPX86_RS11495	COG0347	Belongs to the P(II) protein family
GPX86_RS11520	COG0741	lytic transglycosylase activity
GPX86_RS11520	COG1388	LysM domain
GPX86_RS11525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPX86_RS11530	COG2226	methyltransferase
GPX86_RS11535	COG0328	RNA-DNA hybrid ribonuclease activity
GPX86_RS11540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPX86_RS11550	COG1960	acyl-CoA dehydrogenase activity
GPX86_RS11555	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPX86_RS11560	COG0121	glutamine amidotransferase
GPX86_RS11565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPX86_RS11570	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GPX86_RS11575	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPX86_RS11580	COG1187	pseudouridine synthase activity
GPX86_RS11605	COG2217	Heavy metal translocating P-type atpase
GPX86_RS11605	COG2608	mercury ion transmembrane transporter activity
GPX86_RS11610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPX86_RS11650	COG2747	anti-sigma28 factor FlgM
GPX86_RS11660	COG0784	Response regulator, receiver
GPX86_RS11660	COG0835	chemotaxis
GPX86_RS11665	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPX86_RS11670	COG1815	bacterial-type flagellum-dependent cell motility
GPX86_RS11675	COG1558	bacterial-type flagellum-dependent cell motility
GPX86_RS11680	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPX86_RS11685	COG1749	Flagellar hook protein flgE
GPX86_RS11690	COG4787	bacterial-type flagellum-dependent cell motility
GPX86_RS11695	COG4786	Flagellar basal body rod
GPX86_RS11700	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GPX86_RS11705	COG1706	bacterial-type flagellum-dependent cell motility
GPX86_RS11710	COG3951	Flagellar rod assembly protein muramidase FlgJ
GPX86_RS11710	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPX86_RS11725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPX86_RS11730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPX86_RS11805	COG0012	GTP binding
GPX86_RS11810	COG0193	aminoacyl-tRNA hydrolase activity
GPX86_RS11815	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPX86_RS11820	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPX86_RS11825	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GPX86_RS11830	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPX86_RS11835	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPX86_RS11840	COG2890	protein-(glutamine-N5) methyltransferase activity
GPX86_RS11845	COG3094	Invasion gene expression up-regulator, SirB
GPX86_RS11850	COG2912	Transglutaminase-like superfamily
GPX86_RS11860	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPX86_RS11865	COG2233	PERMEase
GPX86_RS11880	COG1393	Belongs to the ArsC family
GPX86_RS11885	COG4783	chaperone-mediated protein folding
GPX86_RS11900	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPX86_RS11905	COG2716	regulation of RNA biosynthetic process
GPX86_RS11910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPX86_RS11915	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GPX86_RS11925	COG1876	peptidase activity
GPX86_RS11930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPX86_RS11935	COG1393	Belongs to the ArsC family
GPX86_RS11960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPX86_RS11965	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPX86_RS11970	COG1334	flagellar protein FlaG
GPX86_RS11975	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPX86_RS11985	COG1516	flagellar protein fliS
GPX86_RS11990	COG2204	response regulator
GPX86_RS11995	COG4191	Histidine kinase
GPX86_RS12000	COG2204	response regulator
GPX86_RS12005	COG1677	Flagellar hook-basal body complex protein FliE
GPX86_RS12015	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPX86_RS12065	COG1987	bacterial-type flagellum assembly
GPX86_RS12080	COG2840	Smr protein MutS2
GPX86_RS12085	COG2890	protein-(glutamine-N5) methyltransferase activity
GPX86_RS12090	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPX86_RS12095	COG2860	membrane
GPX86_RS12100	COG3101	peptidyl-lysine hydroxylation
GPX86_RS12110	COG0431	NADPH-dependent FMN reductase
GPX86_RS12115	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GPX86_RS12115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPX86_RS12120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPX86_RS12125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPX86_RS12130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPX86_RS12135	COG0735	belongs to the Fur family
GPX86_RS12145	COG0583	DNA-binding transcription factor activity
GPX86_RS12150	COG1380	Effector of murein hydrolase LrgA
GPX86_RS12155	COG1346	cytolysis
GPX86_RS12165	COG0596	Alpha beta hydrolase
GPX86_RS12170	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GPX86_RS12175	COG0033	Phosphoglucomutase
GPX86_RS12185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPX86_RS12195	COG2009	succinate dehydrogenase
GPX86_RS12200	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GPX86_RS12215	COG0567	Dehydrogenase, E1 component
GPX86_RS12220	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPX86_RS12235	COG0626	cystathionine gamma-synthase activity
GPX86_RS12240	COG1757	Na H antiporter
GPX86_RS12245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPX86_RS12250	COG1121	(ABC) transporter
GPX86_RS12255	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GPX86_RS12265	COG1918	ferrous iron import across plasma membrane
GPX86_RS12270	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GPX86_RS12290	COG3102	Protein conserved in bacteria
GPX86_RS12295	COG1025	Belongs to the peptidase M16 family
GPX86_RS12300	COG2062	phosphohistidine phosphatase, SixA
GPX86_RS12315	COG0455	bacterial-type flagellum organization
GPX86_RS12330	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GPX86_RS12335	COG0643	Histidine kinase
GPX86_RS12335	COG2198	Histidine kinase
GPX86_RS12340	COG2201	protein-glutamate methylesterase activity
GPX86_RS12345	COG1192	Involved in chromosome partitioning
GPX86_RS12355	COG0835	chemotaxis
GPX86_RS12365	COG2853	Lipoprotein
GPX86_RS12385	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GPX86_RS12390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPX86_RS12400	COG3639	organic phosphonate transmembrane transporter activity
GPX86_RS12405	COG3639	organic phosphonate transmembrane transporter activity
GPX86_RS12410	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GPX86_RS12430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPX86_RS12430	COG3453	Protein conserved in bacteria
GPX86_RS12440	COG0488	(ABC) transporter
GPX86_RS12445	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPX86_RS12455	COG2130	NADP-dependent
GPX86_RS12460	COG1309	transcriptional regulator
GPX86_RS12465	COG1403	HNH endonuclease
GPX86_RS12490	COG0674	pyruvate-flavodoxin oxidoreductase activity
GPX86_RS12490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GPX86_RS12490	COG1013	pyruvate-flavodoxin oxidoreductase activity
GPX86_RS12490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GPX86_RS12495	COG2205	protein histidine kinase activity
GPX86_RS12500	COG0745	RESPONSE REGULATOR receiver
GPX86_RS12505	COG3122	Protein conserved in bacteria
GPX86_RS12520	COG2226	methyltransferase
GPX86_RS12530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPX86_RS12535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPX86_RS12545	COG3139	Protein of unknown function (DUF1315)
GPX86_RS12550	COG0252	asparaginase activity
GPX86_RS12555	COG0616	signal peptide processing
GPX86_RS12560	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPX86_RS12560	COG1902	pentaerythritol trinitrate reductase activity
GPX86_RS12565	COG0788	formyltetrahydrofolate deformylase activity
GPX86_RS12575	COG1199	ATP-dependent helicase activity
GPX86_RS12580	COG1214	PFAM Peptidase M22, glycoprotease
GPX86_RS12595	COG2226	methyltransferase
GPX86_RS12595	COG1073	alpha beta
GPX86_RS12600	COG0318	PFAM AMP-dependent synthetase and ligase
GPX86_RS12605	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GPX86_RS12615	COG2894	cell division
GPX86_RS12620	COG0850	regulation of cytokinetic process
GPX86_RS12625	COG3100	YcgL domain-containing protein
GPX86_RS12630	COG2951	lytic endotransglycosylase activity
GPX86_RS12635	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GPX86_RS12640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPX86_RS12645	COG0521	Mo-molybdopterin cofactor biosynthetic process
GPX86_RS12655	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPX86_RS12660	COG0314	molybdopterin synthase activity
GPX86_RS12665	COG0516	GMP reductase activity
GPX86_RS12665	COG0517	IMP dehydrogenase activity
GPX86_RS12685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPX86_RS12685	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPX86_RS12690	COG0489	protein tyrosine kinase activity
GPX86_RS12695	COG0572	uridine kinase
GPX86_RS12700	COG2982	Protein involved in outer membrane biogenesis
GPX86_RS12705	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GPX86_RS12710	COG2067	long-chain fatty acid transport protein
GPX86_RS12715	COG2067	long-chain fatty acid transport protein
GPX86_RS12720	COG0183	Belongs to the thiolase family
GPX86_RS12725	COG1024	Enoyl-CoA hydratase
GPX86_RS12725	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPX86_RS12730	COG0583	DNA-binding transcription factor activity
GPX86_RS12735	COG0745	RESPONSE REGULATOR receiver
GPX86_RS12740	COG2832	Protein of unknown function (DUF454)
GPX86_RS12745	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPX86_RS12760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPX86_RS12775	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GPX86_RS12865	COG4695	Portal protein
GPX86_RS12995	COG2239	Acts as a magnesium transporter
GPX86_RS13005	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPX86_RS13060	COG2974	May be involved in recombination
GPX86_RS13180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPX86_RS13195	COG0450	alkyl hydroperoxide reductase
GPX86_RS13220	COG0640	Transcriptional regulator
GPX86_RS13240	COG1328	CTP reductase activity
GPX86_RS13255	COG4067	protein conserved in archaea
GPX86_RS13255	COG0189	ligase activity
GPX86_RS13260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX86_RS13260	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GPX86_RS13260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPX86_RS13265	COG1105	Belongs to the carbohydrate kinase PfkB family
GPX86_RS13270	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX86_RS13270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX86_RS13275	COG1609	Transcriptional regulator
GPX86_RS13280	COG0420	3'-5' exonuclease activity
GPX86_RS13285	COG0419	ATPase involved in DNA repair
GPX86_RS13290	COG0784	Response regulator, receiver
GPX86_RS13290	COG2205	protein histidine kinase activity
GPX86_RS13295	COG0156	8-amino-7-oxononanoate synthase activity
GPX86_RS13300	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GPX86_RS13305	COG1011	Hydrolase
GPX86_RS13310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPX86_RS13315	COG2188	Transcriptional regulator
GPX86_RS13340	COG2314	TM2 domain
GPX86_RS13375	COG0038	chloride channel
GPX86_RS13380	COG0523	cobalamin synthesis protein
GPX86_RS13385	COG1136	(ABC) transporter
GPX86_RS13385	COG0577	efflux transmembrane transporter activity
GPX86_RS13390	COG0577	efflux transmembrane transporter activity
GPX86_RS13390	COG1136	(ABC) transporter
GPX86_RS13395	COG0577	efflux transmembrane transporter activity
GPX86_RS13395	COG1136	(ABC) transporter
GPX86_RS13410	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPX86_RS13420	COG4139	cobalamin transport
GPX86_RS13430	COG2610	gluconate transmembrane transporter activity
GPX86_RS13435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPX86_RS13440	COG3622	Belongs to the hyi family
GPX86_RS13445	COG0235	Class ii aldolase
GPX86_RS13450	COG3395	kinase activity
GPX86_RS13455	COG2084	Dehydrogenase
GPX86_RS13460	COG1349	DNA-binding transcription factor activity
GPX86_RS13465	COG3181	Tripartite tricarboxylate transporter family receptor
GPX86_RS13490	COG0488	(ABC) transporter
GPX86_RS13500	COG1328	CTP reductase activity
GPX86_RS13505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPX86_RS13530	COG0517	IMP dehydrogenase activity
GPX86_RS13540	COG3038	cytochrome b561
GPX86_RS13545	COG2353	YceI-like domain
GPX86_RS13550	COG2116	formate transmembrane transporter activity
GPX86_RS13555	COG0583	DNA-binding transcription factor activity
GPX86_RS13565	COG3593	DNA synthesis involved in DNA repair
GPX86_RS13570	COG0737	Belongs to the 5'-nucleotidase family
GPX86_RS13575	COG0861	Integral membrane protein TerC family
GPX86_RS13585	COG2824	Alkylphosphonate utilization operon protein PhnA
GPX86_RS13595	COG2050	protein possibly involved in aromatic compounds catabolism
GPX86_RS13610	COG0583	DNA-binding transcription factor activity
GPX86_RS13615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPX86_RS13615	COG1042	CoA-binding domain protein
GPX86_RS13615	COG0045	succinate-CoA ligase (ADP-forming) activity
GPX86_RS13625	COG1181	Belongs to the D-alanine--D-alanine ligase family
GPX86_RS13640	COG0023	Translation Initiation Factor
GPX86_RS13645	COG2873	o-acetylhomoserine
GPX86_RS13665	COG0745	RESPONSE REGULATOR receiver
GPX86_RS13675	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GPX86_RS13680	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GPX86_RS13695	COG3706	GGDEF domain
GPX86_RS13705	COG0653	protein targeting
GPX86_RS13970	COG4115	mRNA cleavage
GPX86_RS13975	COG2161	toxin-antitoxin pair type II binding
GPX86_RS13995	COG0456	acetyltransferase
GPX86_RS14020	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPX86_RS14025	COG0513	Belongs to the DEAD box helicase family
GPX86_RS14030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GPX86_RS14030	COG2885	chlorophyll binding
GPX86_RS14035	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GPX86_RS14065	COG0444	Belongs to the ABC transporter superfamily
GPX86_RS14070	COG4608	Belongs to the ABC transporter superfamily
GPX86_RS14075	COG0601	transmembrane transport
GPX86_RS14080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPX86_RS14090	COG0527	aspartate kinase activity
GPX86_RS14095	COG0662	Cupin 2, conserved barrel domain protein
GPX86_RS14100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPX86_RS14105	COG0456	acetyltransferase
GPX86_RS14110	COG2154	pterin-4-alpha-carbinolamine dehydratase
GPX86_RS14115	COG3186	Phenylalanine-4-hydroxylase
GPX86_RS14120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPX86_RS14145	COG1765	OsmC-like protein
GPX86_RS14170	COG0625	glutathione transferase activity
GPX86_RS14175	COG1278	Cold shock
GPX86_RS14185	COG4145	pantothenate transmembrane transporter activity
GPX86_RS14190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPX86_RS14195	COG4604	ABC transporter, ATP-binding protein
GPX86_RS14200	COG4605	iron ion homeostasis
GPX86_RS14205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPX86_RS14210	COG4607	ABC-type enterochelin transport system periplasmic component
GPX86_RS14220	COG2814	Major facilitator Superfamily
GPX86_RS14230	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPX86_RS14235	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GPX86_RS14240	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPX86_RS14245	COG4989	oxidoreductase activity
GPX86_RS14255	COG0366	Alpha amylase catalytic
GPX86_RS14260	COG2067	long-chain fatty acid transport protein
GPX86_RS14265	COG2267	carboxylic ester hydrolase activity
GPX86_RS14270	COG3047	cAMP biosynthetic process
GPX86_RS14275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPX86_RS14280	COG0784	Response regulator, receiver
GPX86_RS14280	COG0835	chemotaxis
GPX86_RS14285	COG3706	GGDEF domain
GPX86_RS14290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GPX86_RS14305	COG1741	Belongs to the pirin family
GPX86_RS14310	COG3123	guanosine phosphorylase activity
GPX86_RS14320	COG1067	ATP-dependent peptidase activity
GPX86_RS14330	COG0583	DNA-binding transcription factor activity
GPX86_RS14335	COG1620	l-lactate permease
GPX86_RS14340	COG1304	FMN binding
GPX86_RS14350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPX86_RS14355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPX86_RS14360	COG1280	lysine exporter protein (LysE YggA)
GPX86_RS14365	COG0179	Fumarylacetoacetate (FAA) hydrolase
GPX86_RS14385	COG5001	Diguanylate cyclase
GPX86_RS14390	COG0739	heme binding
GPX86_RS14400	COG0659	secondary active sulfate transmembrane transporter activity
GPX86_RS14410	COG0513	Belongs to the DEAD box helicase family
GPX86_RS14435	COG0363	glucosamine-6-phosphate deaminase activity
GPX86_RS14445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPX86_RS14455	COG2771	luxR family
GPX86_RS14455	COG2200	EAL domain
GPX86_RS14475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPX86_RS14485	COG2259	Doxx family
GPX86_RS14495	COG2814	Major facilitator Superfamily
GPX86_RS14510	COG0848	biopolymer transport protein
GPX86_RS14515	COG0811	peptide transport
GPX86_RS14520	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GPX86_RS14540	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GPX86_RS14550	COG1957	nucleoside hydrolase
GPX86_RS14555	COG4628	conserved protein (DUF2132)
GPX86_RS14565	COG0583	DNA-binding transcription factor activity
GPX86_RS14590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPX86_RS14610	COG2382	esterase
GPX86_RS14635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPX86_RS14640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GPX86_RS14640	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPX86_RS14650	COG2201	protein-glutamate methylesterase activity
GPX86_RS14660	COG1278	Cold shock
GPX86_RS14665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPX86_RS14665	COG1017	nitric oxide dioxygenase activity
GPX86_RS14670	COG3604	Transcriptional regulator
GPX86_RS14680	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPX86_RS14685	COG0366	Alpha amylase catalytic
GPX86_RS14700	COG0840	transmembrane signaling receptor activity
GPX86_RS14705	COG0714	Associated with various cellular activities
GPX86_RS14720	COG2304	oxidoreductase activity
GPX86_RS14740	COG3724	N-succinylarginine dihydrolase activity
GPX86_RS14750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPX86_RS14765	COG0513	Belongs to the DEAD box helicase family
GPX86_RS14775	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPX86_RS14780	COG2184	nucleotidyltransferase activity
GPX86_RS14790	COG0840	transmembrane signaling receptor activity
GPX86_RS14800	COG3710	Transcriptional regulator
GPX86_RS14830	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GPX86_RS14835	COG4789	Type iii secretion
GPX86_RS14915	COG3710	Transcriptional regulator
GPX86_RS14975	COG4790	Type iii secretion
GPX86_RS14985	COG2197	response regulator
GPX86_RS15000	COG3530	Putative quorum-sensing-regulated virulence factor
GPX86_RS15010	COG0583	DNA-binding transcription factor activity
GPX86_RS15025	COG2271	Major facilitator Superfamily
GPX86_RS15030	COG0584	glycerophosphoryl diester phosphodiesterase
GPX86_RS15035	COG1609	Transcriptional regulator
GPX86_RS15040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPX86_RS15045	COG1879	ABC-type sugar transport system periplasmic component
GPX86_RS15050	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPX86_RS15055	COG1129	ABC transporter
GPX86_RS15060	COG1869	D-ribose catabolic process
GPX86_RS15080	COG0564	pseudouridine synthase activity
GPX86_RS15090	COG0739	heme binding
GPX86_RS15095	COG2213	PTS system mannitol-specific
GPX86_RS15095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPX86_RS15105	COG3722	fumarate hydratase activity
GPX86_RS15115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPX86_RS15125	COG5002	protein histidine kinase activity
GPX86_RS15135	COG0095	Lipoate-protein ligase
GPX86_RS15145	COG0477	Major facilitator Superfamily
GPX86_RS15150	COG4628	conserved protein (DUF2132)
GPX86_RS15165	COG2076	Multidrug Resistance protein
GPX86_RS15175	COG0702	epimerase
GPX86_RS15180	COG0583	DNA-binding transcription factor activity
GPX86_RS15185	COG0840	transmembrane signaling receptor activity
GPX86_RS15200	COG0513	Belongs to the DEAD box helicase family
GPX86_RS15205	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPX86_RS15210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPX86_RS15235	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GPX86_RS15240	COG0259	pyridoxamine-phosphate oxidase activity
GPX86_RS15250	COG3706	GGDEF domain
GPX86_RS15250	COG0745	RESPONSE REGULATOR receiver
GPX86_RS15255	COG2084	Dehydrogenase
GPX86_RS15260	COG0217	transcriptional regulatory protein
GPX86_RS15290	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPX86_RS15295	COG1444	tRNA N-acetyltransferase activity
GPX86_RS15300	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPX86_RS15310	COG3046	protein related to deoxyribodipyrimidine photolyase
GPX86_RS15325	COG3706	GGDEF domain
GPX86_RS15325	COG0745	RESPONSE REGULATOR receiver
GPX86_RS15340	COG2909	trisaccharide binding
GPX86_RS15345	COG0058	SHG alpha-glucan phosphorylase activity
GPX86_RS15350	COG1640	4-alpha-glucanotransferase
GPX86_RS15355	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GPX86_RS15365	COG0471	metal ion transport
GPX86_RS15370	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPX86_RS15380	COG0840	transmembrane signaling receptor activity
GPX86_RS15395	COG0010	Belongs to the arginase family
GPX86_RS15400	COG0671	phosphoesterase, PA-phosphatase related
GPX86_RS15410	COG1132	(ABC) transporter
GPX86_RS15420	COG4580	involved in the transport of maltose and maltodextrins
GPX86_RS15435	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GPX86_RS15450	COG3706	GGDEF domain
GPX86_RS15465	COG0813	purine-nucleoside phosphorylase activity
GPX86_RS15470	COG3272	Protein of unknown function (DUF1722)
GPX86_RS15475	COG0789	Transcriptional regulator
GPX86_RS15480	COG0415	Belongs to the DNA photolyase family
GPX86_RS15485	COG1376	ErfK ybiS ycfS ynhG family protein
GPX86_RS15485	COG1388	LysM domain
GPX86_RS15490	COG0786	glutamate:sodium symporter activity
GPX86_RS15495	COG0786	glutamate:sodium symporter activity
GPX86_RS15505	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GPX86_RS15510	COG1342	Belongs to the UPF0251 family
GPX86_RS15525	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPX86_RS15530	COG0673	inositol 2-dehydrogenase activity
GPX86_RS15535	COG1472	Belongs to the glycosyl hydrolase 3 family
GPX86_RS15540	COG3876	Protein conserved in bacteria
GPX86_RS15545	COG3539	Fimbrial protein
GPX86_RS15550	COG3539	Fimbrial protein
GPX86_RS15570	COG3121	Chaperone
GPX86_RS15595	COG3539	Fimbrial protein
GPX86_RS15600	COG2197	response regulator
GPX86_RS15605	COG2205	protein histidine kinase activity
GPX86_RS15605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPX86_RS15610	COG2200	EAL domain
GPX86_RS15610	COG2199	diguanylate cyclase activity
GPX86_RS15615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GPX86_RS15620	COG0783	Belongs to the Dps family
GPX86_RS15625	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GPX86_RS15645	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPX86_RS15650	COG0363	glucosamine-6-phosphate deaminase activity
GPX86_RS15655	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPX86_RS15660	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPX86_RS15690	COG3240	lipase activity
GPX86_RS15695	COG0156	8-amino-7-oxononanoate synthase activity
GPX86_RS15700	COG1063	alcohol dehydrogenase
GPX86_RS15725	COG2376	Dihydroxyacetone kinase
GPX86_RS15730	COG1461	Dihydroxyacetone kinase
GPX86_RS15745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPX86_RS15750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPX86_RS15760	COG3842	ATPase activity
GPX86_RS15770	COG1175	transmembrane transport
GPX86_RS15775	COG3833	ABC-type maltose transport systems, permease component
GPX86_RS15795	COG1607	acyl-coa hydrolase
GPX86_RS15810	COG1349	DNA-binding transcription factor activity
GPX86_RS15830	COG0418	dihydroorotase activity
GPX86_RS15835	COG0633	Ferredoxin
GPX86_RS15835	COG3217	Mosc domain protein beta barrel domain protein
GPX86_RS15865	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GPX86_RS15870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPX86_RS15875	COG4558	Periplasmic binding protein
GPX86_RS15880	COG3721	Heme iron utilization protein
GPX86_RS15885	COG0748	coenzyme F420 binding
GPX86_RS15900	COG1166	arginine decarboxylase activity
GPX86_RS15905	COG0010	Belongs to the arginase family
GPX86_RS15910	COG1686	Belongs to the peptidase S11 family
GPX86_RS15935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPX86_RS15950	COG2814	Major facilitator Superfamily
GPX86_RS15955	COG3118	belongs to the thioredoxin family
GPX86_RS15960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPX86_RS15965	COG0247	lactate metabolic process
GPX86_RS15970	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GPX86_RS15975	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPX86_RS15980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPX86_RS16010	COG2827	Endonuclease containing a URI domain
GPX86_RS16015	COG1879	ABC-type sugar transport system periplasmic component
GPX86_RS16020	COG5002	protein histidine kinase activity
GPX86_RS16020	COG0784	Response regulator, receiver
GPX86_RS16030	COG0725	ABC transporter, periplasmic molybdate-binding protein
GPX86_RS16040	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GPX86_RS16055	COG1289	transmembrane transporter activity
GPX86_RS16060	COG0210	DNA helicase
GPX86_RS16065	COG1335	isochorismatase
GPX86_RS16070	COG1803	Methylglyoxal synthase
GPX86_RS16085	COG1979	alcohol dehydrogenase
GPX86_RS16090	COG2207	Transcriptional regulator
GPX86_RS16100	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPX86_RS16105	COG3706	GGDEF domain
GPX86_RS16120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPX86_RS16130	COG3604	Transcriptional regulator
GPX86_RS16145	COG0626	cystathionine gamma-synthase activity
GPX86_RS16150	COG0840	transmembrane signaling receptor activity
GPX86_RS16175	COG3069	C4-dicarboxylate transmembrane transporter activity
GPX86_RS16185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPX86_RS16190	COG0545	Peptidyl-prolyl cis-trans isomerase
GPX86_RS16205	COG0840	transmembrane signaling receptor activity
GPX86_RS16215	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPX86_RS16220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPX86_RS16230	COG2897	thiosulfate sulfurtransferase activity
GPX86_RS16235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPX86_RS16240	COG0303	'Molybdopterin
GPX86_RS16245	COG0302	gtp cyclohydrolase
GPX86_RS16250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPX86_RS16250	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPX86_RS16255	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GPX86_RS16260	COG1278	Cold shock
GPX86_RS16270	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPX86_RS16270	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPX86_RS16285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GPX86_RS16300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPX86_RS16355	COG0546	phosphoglycolate phosphatase activity
GPX86_RS16375	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPX86_RS16385	COG4181	ATPase activity
GPX86_RS16390	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GPX86_RS16400	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GPX86_RS16410	COG0840	transmembrane signaling receptor activity
GPX86_RS16415	COG0814	amino acid
GPX86_RS16420	COG0513	Belongs to the DEAD box helicase family
GPX86_RS16440	COG2425	protein containing a von Willebrand factor type A (vWA) domain