locus-tag	class	description
ET951_RS00010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ET951_RS00015	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ET951_RS00020	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ET951_RS00025	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ET951_RS00035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ET951_RS00040	COG3706	GGDEF domain
ET951_RS00050	COG4120	Belongs to the binding-protein-dependent transport system permease family
ET951_RS00065	COG3092	negative regulation of chromosome organization
ET951_RS00070	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ET951_RS00075	COG0857	belongs to the CobB CobQ family
ET951_RS00075	COG0280	phosphate acetyltransferase
ET951_RS00080	COG0435	Glutathione S-transferase
ET951_RS00085	COG4608	Belongs to the ABC transporter superfamily
ET951_RS00095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET951_RS00100	COG0601	transmembrane transport
ET951_RS00115	COG4191	Histidine kinase
ET951_RS00120	COG2204	response regulator
ET951_RS00125	COG5001	Diguanylate cyclase
ET951_RS00125	COG3300	MHYT domain
ET951_RS00130	COG4191	Histidine kinase
ET951_RS00135	COG5002	protein histidine kinase activity
ET951_RS00145	COG2201	protein-glutamate methylesterase activity
ET951_RS00160	COG0009	L-threonylcarbamoyladenylate synthase
ET951_RS00175	COG1881	PFAM PEBP family protein
ET951_RS00200	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET951_RS00215	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET951_RS00220	COG2222	sugar isomerase
ET951_RS00230	COG1349	DNA-binding transcription factor activity
ET951_RS00235	COG1349	DNA-binding transcription factor activity
ET951_RS00250	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ET951_RS00255	COG0640	Transcriptional regulator
ET951_RS00265	COG0590	tRNA wobble adenosine to inosine editing
ET951_RS00270	COG2076	Multidrug Resistance protein
ET951_RS00275	COG2076	Multidrug Resistance protein
ET951_RS00280	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ET951_RS00300	COG1120	ATPase activity
ET951_RS00305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET951_RS00315	COG4264	IucA IucC family
ET951_RS00355	COG0583	DNA-binding transcription factor activity
ET951_RS00380	COG5001	Diguanylate cyclase
ET951_RS00380	COG3300	MHYT domain
ET951_RS00400	COG1946	Acyl-CoA thioesterase
ET951_RS00405	COG1522	sequence-specific DNA binding
ET951_RS00415	COG0616	signal peptide processing
ET951_RS00420	COG1028	Short-chain dehydrogenase reductase Sdr
ET951_RS00425	COG2983	Belongs to the UPF0260 family
ET951_RS00435	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ET951_RS00440	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ET951_RS00445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ET951_RS00450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ET951_RS00455	COG2832	Protein of unknown function (DUF454)
ET951_RS00465	COG0745	RESPONSE REGULATOR receiver
ET951_RS00470	COG0583	DNA-binding transcription factor activity
ET951_RS00475	COG0778	Nitroreductase
ET951_RS00480	COG1250	3-hydroxyacyl-CoA dehydrogenase
ET951_RS00480	COG1024	Enoyl-CoA hydratase
ET951_RS00485	COG0183	Belongs to the thiolase family
ET951_RS00500	COG2067	long-chain fatty acid transport protein
ET951_RS00505	COG2067	long-chain fatty acid transport protein
ET951_RS00510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ET951_RS00515	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ET951_RS00520	COG2982	Protein involved in outer membrane biogenesis
ET951_RS00525	COG0572	uridine kinase
ET951_RS00535	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ET951_RS00535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ET951_RS00545	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ET951_RS00555	COG0617	tRNA 3'-terminal CCA addition
ET951_RS00555	COG0517	IMP dehydrogenase activity
ET951_RS00555	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ET951_RS00560	COG3706	GGDEF domain
ET951_RS00565	COG0314	molybdopterin synthase activity
ET951_RS00570	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ET951_RS00575	COG0315	cyclic pyranopterin monophosphate synthase activity
ET951_RS00580	COG0521	Mo-molybdopterin cofactor biosynthetic process
ET951_RS00585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ET951_RS00590	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ET951_RS00595	COG2198	Histidine kinase
ET951_RS00600	COG2204	response regulator
ET951_RS00605	COG0556	nucleotide-excision repair
ET951_RS00620	COG3119	arylsulfatase activity
ET951_RS00625	COG0641	radical SAM
ET951_RS00630	COG0714	Associated with various cellular activities
ET951_RS00665	COG4657	Part of a membrane complex involved in electron transport
ET951_RS00670	COG2878	Part of a membrane complex involved in electron transport
ET951_RS00675	COG4656	Part of a membrane complex involved in electron transport
ET951_RS00680	COG4658	electron transport chain
ET951_RS00690	COG4660	Part of a membrane complex involved in electron transport
ET951_RS00695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ET951_RS00700	COG0346	lactoylglutathione lyase activity
ET951_RS00715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ET951_RS00720	COG2056	Na+-H+ antiporter family
ET951_RS00725	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ET951_RS00730	COG1286	toxin biosynthetic process
ET951_RS00735	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ET951_RS00740	COG0285	dihydrofolate synthase activity
ET951_RS00745	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ET951_RS00750	COG0101	tRNA pseudouridine synthase activity
ET951_RS00765	COG2190	(PTS) system
ET951_RS00765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET951_RS00765	COG1263	PTS System
ET951_RS00770	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ET951_RS00775	COG1846	Transcriptional regulator
ET951_RS00775	COG1940	carbohydrate kinase activity
ET951_RS00780	COG4651	solute:proton antiporter activity
ET951_RS00780	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ET951_RS00785	COG0367	asparagine synthase
ET951_RS00790	COG0250	Participates in transcription elongation, termination and antitermination
ET951_RS00795	COG3104	oligopeptide transport
ET951_RS00800	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ET951_RS00805	COG0563	adenylate kinase activity
ET951_RS00810	COG0326	Molecular chaperone. Has ATPase activity
ET951_RS00815	COG3710	Transcriptional regulator
ET951_RS00830	COG0622	Phosphoesterase
ET951_RS00835	COG1090	epimerase
ET951_RS00840	COG0300	oxidoreductase activity
ET951_RS00850	COG3118	belongs to the thioredoxin family
ET951_RS00855	COG0330	HflC and HflK could
ET951_RS00860	COG1585	Membrane protein implicated in regulation of membrane protease activity
ET951_RS00865	COG0789	Transcriptional regulator
ET951_RS00880	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ET951_RS00885	COG3115	cell septum assembly
ET951_RS00890	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ET951_RS00895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ET951_RS00900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET951_RS00910	COG2190	(PTS) system
ET951_RS00915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ET951_RS00920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ET951_RS00925	COG1702	phosphate starvation-inducible protein PhoH
ET951_RS00930	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ET951_RS00935	COG4535	Mg2 and Co2 transporter CorC
ET951_RS00940	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ET951_RS00945	COG2888	peptidyl-tyrosine sulfation
ET951_RS00950	COG0495	leucyl-tRNA aminoacylation
ET951_RS00955	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ET951_RS00960	COG1466	dna polymerase III delta subunit
ET951_RS00965	COG0799	negative regulation of ribosome biogenesis
ET951_RS00970	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ET951_RS00975	COG0768	penicillin binding
ET951_RS00980	COG0772	Belongs to the SEDS family
ET951_RS00985	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ET951_RS00990	COG1686	Belongs to the peptidase S11 family
ET951_RS00995	COG2921	Belongs to the UPF0250 family
ET951_RS01000	COG0321	lipoyl(octanoyl) transferase activity
ET951_RS01005	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ET951_RS01015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ET951_RS01040	COG1596	polysaccharide export
ET951_RS01050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ET951_RS01080	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ET951_RS01100	COG1045	serine acetyltransferase
ET951_RS01125	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ET951_RS01130	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ET951_RS01135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ET951_RS01140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ET951_RS01180	COG2205	protein histidine kinase activity
ET951_RS01185	COG0745	RESPONSE REGULATOR receiver
ET951_RS01190	COG0366	Alpha amylase catalytic
ET951_RS01195	COG1263	PTS System
ET951_RS01195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET951_RS01200	COG1609	Transcriptional regulator
ET951_RS01205	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ET951_RS01210	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ET951_RS01215	COG2011	ABC-type metal ion transport system permease component
ET951_RS01220	COG1464	Belongs to the NlpA lipoprotein family
ET951_RS01225	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
ET951_RS01235	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ET951_RS01235	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ET951_RS01250	COG1611	Belongs to the LOG family
ET951_RS01255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ET951_RS01260	COG2363	Small membrane protein
ET951_RS01265	COG0583	DNA-binding transcription factor activity
ET951_RS01275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ET951_RS01275	COG0301	tRNA thio-modification
ET951_RS01285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ET951_RS01290	COG1722	exodeoxyribonuclease VII activity
ET951_RS01295	COG0142	geranyltranstransferase activity
ET951_RS01300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ET951_RS01305	COG0564	pseudouridine synthase activity
ET951_RS01335	COG1671	Belongs to the UPF0178 family
ET951_RS01340	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ET951_RS01345	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ET951_RS01350	COG0254	rRNA binding
ET951_RS01355	COG1720	tRNA m6t6A37 methyltransferase activity
ET951_RS01360	COG0442	prolyl-tRNA aminoacylation
ET951_RS01380	COG3344	reverse transcriptase
ET951_RS01385	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ET951_RS01385	COG0047	phosphoribosylformylglycinamidine synthase activity
ET951_RS01395	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ET951_RS01405	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ET951_RS01435	COG0484	heat shock protein binding
ET951_RS01440	COG0443	Heat shock 70 kDa protein
ET951_RS01445	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ET951_RS01450	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ET951_RS01455	COG0497	DNA recombination
ET951_RS01460	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ET951_RS01465	COG2914	Belongs to the UPF0125 (RnfH) family
ET951_RS01470	COG2867	negative regulation of translational initiation
ET951_RS01475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ET951_RS01485	COG0582	viral genome integration into host DNA
ET951_RS01500	COG3344	reverse transcriptase
ET951_RS01515	COG0739	heme binding
ET951_RS01530	COG0840	transmembrane signaling receptor activity
ET951_RS01535	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ET951_RS01540	COG2207	Transcriptional regulator
ET951_RS01550	COG1459	type II secretion system
ET951_RS01555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ET951_RS01575	COG4796	Type ii and iii secretion system protein
ET951_RS01590	COG2165	general secretion pathway protein
ET951_RS01600	COG3710	Transcriptional regulator
ET951_RS01605	COG0840	transmembrane signaling receptor activity
ET951_RS01610	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ET951_RS01630	COG1012	belongs to the aldehyde dehydrogenase family
ET951_RS01665	COG2003	Belongs to the UPF0758 family
ET951_RS01705	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ET951_RS01710	COG0732	type I restriction modification DNA specificity domain
ET951_RS01715	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ET951_RS01730	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ET951_RS01735	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ET951_RS01740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ET951_RS01760	COG3051	citrate lyase alpha subunit
ET951_RS01765	COG2301	Belongs to the HpcH HpaI aldolase family
ET951_RS01770	COG3052	prosthetic group binding
ET951_RS01775	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ET951_RS01785	COG3630	sodium ion export across plasma membrane
ET951_RS01790	COG5016	pyruvate
ET951_RS01790	COG0511	ligase activity, forming carbon-carbon bonds
ET951_RS01795	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ET951_RS01805	COG4565	transcriptional regulatory protein
ET951_RS01815	COG2200	EAL domain
ET951_RS01830	COG0583	DNA-binding transcription factor activity
ET951_RS01840	COG1115	amino acid carrier protein
ET951_RS01845	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ET951_RS01850	COG0583	DNA-binding transcription factor activity
ET951_RS01855	COG1584	GPR1 FUN34 yaaH family protein
ET951_RS01865	COG0519	Catalyzes the synthesis of GMP from XMP
ET951_RS01865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ET951_RS01870	COG0517	IMP dehydrogenase activity
ET951_RS01870	COG0516	GMP reductase activity
ET951_RS01875	COG1570	exodeoxyribonuclease VII activity
ET951_RS01890	COG1160	GTP binding
ET951_RS01895	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ET951_RS01900	COG2976	Protein conserved in bacteria
ET951_RS01905	COG0124	histidyl-tRNA synthetase
ET951_RS01910	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ET951_RS01915	COG1426	Protein conserved in bacteria
ET951_RS01920	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ET951_RS01925	COG0105	UTP biosynthetic process
ET951_RS01930	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ET951_RS01935	COG2975	iron-sulfur cluster assembly
ET951_RS01940	COG0633	Ferredoxin
ET951_RS01950	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ET951_RS01960	COG0822	iron-sulfur transferase activity
ET951_RS01970	COG1959	2 iron, 2 sulfur cluster binding
ET951_RS01980	COG0483	inositol monophosphate 1-phosphatase activity
ET951_RS01985	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ET951_RS01990	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ET951_RS01995	COG1862	Preprotein translocase
ET951_RS02005	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ET951_RS02010	COG0517	IMP dehydrogenase activity
ET951_RS02015	COG0840	transmembrane signaling receptor activity
ET951_RS02025	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ET951_RS02030	COG0583	DNA-binding transcription factor activity
ET951_RS02035	COG0450	alkyl hydroperoxide reductase
ET951_RS02040	COG3142	Participates in the control of copper homeostasis
ET951_RS02055	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ET951_RS02060	COG0581	inorganic phosphate transmembrane transporter activity
ET951_RS02070	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ET951_RS02075	COG0248	Ppx GppA phosphatase
ET951_RS02085	COG5002	protein histidine kinase activity
ET951_RS02090	COG0745	RESPONSE REGULATOR receiver
ET951_RS02100	COG0826	peptidase U32
ET951_RS02105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ET951_RS02155	COG0542	response to heat
ET951_RS02160	COG1496	oxidoreductase activity
ET951_RS02165	COG0564	pseudouridine synthase activity
ET951_RS02170	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ET951_RS02175	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ET951_RS02180	COG1605	Chorismate mutase
ET951_RS02180	COG0077	Prephenate dehydratase
ET951_RS02185	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ET951_RS02190	COG5001	Diguanylate cyclase
ET951_RS02200	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ET951_RS02210	COG0488	(ABC) transporter
ET951_RS02220	COG1605	Chorismate mutase
ET951_RS02220	COG0287	Prephenate dehydrogenase
ET951_RS02225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ET951_RS02230	COG3275	phosphorelay sensor kinase activity
ET951_RS02235	COG3279	Response regulator of the LytR AlgR family
ET951_RS02245	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ET951_RS02250	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ET951_RS02265	COG1966	Carbon starvation protein
ET951_RS02270	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ET951_RS02275	COG1047	Peptidyl-prolyl cis-trans
ET951_RS02280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ET951_RS02290	COG0196	riboflavin kinase activity
ET951_RS02295	COG0728	peptidoglycan biosynthetic process
ET951_RS02300	COG0268	Binds directly to 16S ribosomal RNA
ET951_RS02305	COG0640	Transcriptional regulator
ET951_RS02310	COG0583	DNA-binding transcription factor activity
ET951_RS02315	COG1283	sodium-dependent phosphate transmembrane transporter activity
ET951_RS02320	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ET951_RS02325	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ET951_RS02330	COG0730	response to heat
ET951_RS02335	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ET951_RS02340	COG0494	nUDIX hydrolase
ET951_RS02345	COG3066	DNA modification
ET951_RS02350	COG0667	Aldo Keto reductase
ET951_RS02360	COG2204	response regulator
ET951_RS02365	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ET951_RS02385	COG0513	Belongs to the DEAD box helicase family
ET951_RS02410	COG3153	acetyltransferase
ET951_RS02415	COG3154	lipid carrier protein
ET951_RS02425	COG0826	peptidase U32
ET951_RS02430	COG0826	peptidase U32
ET951_RS02455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ET951_RS02465	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ET951_RS02470	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ET951_RS02475	COG0195	Participates in both transcription termination and antitermination
ET951_RS02480	COG0779	Required for maturation of 30S ribosomal subunits
ET951_RS02495	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ET951_RS02505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ET951_RS02510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ET951_RS02515	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ET951_RS02520	COG1534	Rna-binding protein
ET951_RS02525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ET951_RS02530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ET951_RS02535	COG2027	D-alanyl-D-alanine carboxypeptidase
ET951_RS02540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ET951_RS02545	COG0739	heme binding
ET951_RS02560	COG0316	Belongs to the HesB IscA family
ET951_RS02565	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ET951_RS02575	COG0628	permease
ET951_RS02580	COG2813	Specifically methylates the guanine in position
ET951_RS02590	COG0747	negative chemotaxis
ET951_RS02600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET951_RS02605	COG0444	Belongs to the ABC transporter superfamily
ET951_RS02610	COG4608	Belongs to the ABC transporter superfamily
ET951_RS02620	COG2971	BadF BadG BcrA BcrD
ET951_RS02635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ET951_RS02640	COG3842	ATPase activity
ET951_RS02650	COG1840	ABC-type Fe3 transport system, periplasmic component
ET951_RS02655	COG0004	ammonium transporteR
ET951_RS02660	COG0347	Belongs to the P(II) protein family
ET951_RS02665	COG3112	Uncharacterised protein family (UPF0231)
ET951_RS02675	COG1752	Esterase of the alpha-beta hydrolase superfamily
ET951_RS02680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ET951_RS02685	COG1643	Atp-dependent helicase
ET951_RS02690	COG1489	DNA binding
ET951_RS02700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ET951_RS02710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ET951_RS02715	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ET951_RS02720	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ET951_RS02725	COG0842	Transport permease protein
ET951_RS02730	COG1131	(ABC) transporter
ET951_RS02735	COG0659	secondary active sulfate transmembrane transporter activity
ET951_RS02740	COG0288	reversible hydration of carbon dioxide
ET951_RS02755	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ET951_RS02760	COG3107	peptidoglycan biosynthetic process
ET951_RS02765	COG0792	nuclease activity
ET951_RS02770	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ET951_RS02775	COG2823	Periplasmic or secreted lipoprotein
ET951_RS02780	COG2969	positive regulation of protein catabolic process
ET951_RS02785	COG0625	glutathione transferase activity
ET951_RS02790	COG2857	Cytochrome c1
ET951_RS02795	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ET951_RS02800	COG0723	plastoquinol--plastocyanin reductase activity
ET951_RS02805	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ET951_RS02810	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ET951_RS02830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ET951_RS02835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ET951_RS02840	COG0335	large ribosomal subunit rRNA binding
ET951_RS02845	COG0336	Belongs to the RNA methyltransferase TrmD family
ET951_RS02850	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ET951_RS02855	COG0228	four-way junction DNA binding
ET951_RS02865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ET951_RS02870	COG4137	Cytochrome C assembly protein
ET951_RS02875	COG4536	flavin adenine dinucleotide binding
ET951_RS02880	COG1854	S-ribosylhomocysteine lyase activity
ET951_RS02885	COG2918	glutathione biosynthetic process
ET951_RS02890	COG0612	Peptidase, M16
ET951_RS02895	COG1238	metal cluster binding
ET951_RS02905	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ET951_RS02910	COG5016	pyruvate
ET951_RS02910	COG0511	ligase activity, forming carbon-carbon bonds
ET951_RS02915	COG3630	sodium ion export across plasma membrane
ET951_RS02960	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ET951_RS02965	COG0527	aspartate kinase activity
ET951_RS02970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ET951_RS02980	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ET951_RS02985	COG1546	Belongs to the CinA family
ET951_RS02990	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ET951_RS02995	COG4208	sulfate ABC transporter
ET951_RS03015	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ET951_RS03020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ET951_RS03030	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ET951_RS03035	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ET951_RS03040	COG0585	pseudouridine synthase activity
ET951_RS03045	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ET951_RS03050	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ET951_RS03055	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ET951_RS03060	COG1968	undecaprenyl-diphosphatase activity
ET951_RS03065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ET951_RS03070	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ET951_RS03075	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ET951_RS03080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ET951_RS03085	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ET951_RS03090	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ET951_RS03095	COG1610	YqeY-like protein
ET951_RS03100	COG0358	DNA primase activity
ET951_RS03115	COG0582	viral genome integration into host DNA
ET951_RS03145	COG2003	Belongs to the UPF0758 family
ET951_RS03180	COG1479	Protein of unknown function DUF262
ET951_RS03215	COG0328	RNA-DNA hybrid ribonuclease activity
ET951_RS03250	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ET951_RS03255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ET951_RS03260	COG1349	DNA-binding transcription factor activity
ET951_RS03280	COG1279	arginine transmembrane transporter activity
ET951_RS03285	COG0668	transmembrane transport
ET951_RS03290	COG0191	fructose-bisphosphate aldolase activity
ET951_RS03295	COG0126	phosphoglycerate kinase activity
ET951_RS03300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ET951_RS03305	COG4771	TonB-dependent receptor
ET951_RS03310	COG0583	DNA-binding transcription factor activity
ET951_RS03315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ET951_RS03325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ET951_RS03330	COG3091	SprT-like family
ET951_RS03335	COG2356	endonuclease I
ET951_RS03340	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ET951_RS03345	COG0189	ligase activity
ET951_RS03350	COG1678	Uncharacterized ACR, COG1678
ET951_RS03355	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ET951_RS03360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ET951_RS03380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ET951_RS03385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ET951_RS03390	COG0762	integral membrane protein
ET951_RS03395	COG1872	DUF167
ET951_RS03405	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ET951_RS03410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ET951_RS03420	COG2066	Belongs to the glutaminase family
ET951_RS03425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ET951_RS03430	COG1194	a g-specific adenine glycosylase
ET951_RS03435	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ET951_RS03440	COG0741	lytic transglycosylase activity
ET951_RS03495	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ET951_RS03500	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ET951_RS03505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ET951_RS03510	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ET951_RS03515	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ET951_RS03520	COG2967	ApaG domain
ET951_RS03525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ET951_RS03535	COG3610	response to peptide
ET951_RS03540	COG2966	Psort location CytoplasmicMembrane, score
ET951_RS03545	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ET951_RS03550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ET951_RS03555	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ET951_RS03560	COG0142	geranyltranstransferase activity
ET951_RS03565	COG0531	amino acid
ET951_RS03570	COG0039	L-malate dehydrogenase activity
ET951_RS03575	COG1438	arginine binding
ET951_RS03580	COG2358	TRAP transporter, solute receptor (TAXI family
ET951_RS03590	COG0589	response to stress
ET951_RS03605	COG2706	6-phosphogluconolactonase activity
ET951_RS03615	COG4145	pantothenate transmembrane transporter activity
ET951_RS03625	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ET951_RS03635	COG1737	Transcriptional regulator
ET951_RS03635	COG0837	glucose binding
ET951_RS03645	COG2235	arginine
ET951_RS03650	COG3344	reverse transcriptase
ET951_RS03655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ET951_RS03665	COG0312	modulator of DNA gyrase
ET951_RS03670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ET951_RS03675	COG3164	Protein of unknown function
ET951_RS03685	COG0424	maF-like protein
ET951_RS03690	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ET951_RS03695	COG1792	Involved in formation and maintenance of cell shape
ET951_RS03700	COG1077	Cell shape determining protein MreB Mrl
ET951_RS03735	COG2165	general secretion pathway protein
ET951_RS03750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ET951_RS03760	COG3267	Type II secretory pathway component ExeA
ET951_RS03760	COG3409	Peptidoglycan-binding domain 1 protein
ET951_RS03785	COG2200	EAL domain
ET951_RS03785	COG2199	diguanylate cyclase activity
ET951_RS03805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ET951_RS03815	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ET951_RS03820	COG0527	aspartate kinase activity
ET951_RS03825	COG1410	methionine synthase
ET951_RS03825	COG0646	methionine synthase
ET951_RS03890	COG0175	sulfate reduction
ET951_RS03900	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ET951_RS03920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ET951_RS03925	COG0735	belongs to the Fur family
ET951_RS03935	COG0166	Belongs to the GPI family
ET951_RS03945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ET951_RS03960	COG0359	binds to the 23S rRNA
ET951_RS03965	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ET951_RS03970	COG2965	DNA replication, synthesis of RNA primer
ET951_RS03975	COG0360	Binds together with S18 to 16S ribosomal RNA
ET951_RS03985	COG2906	2 iron, 2 sulfur cluster binding
ET951_RS03990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ET951_RS03995	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ET951_RS04000	COG0049	tRNA binding
ET951_RS04015	COG2923	Belongs to the DsrF TusC family
ET951_RS04020	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ET951_RS04025	COG2964	Protein conserved in bacteria
ET951_RS04030	COG0545	Peptidyl-prolyl cis-trans isomerase
ET951_RS04040	COG2900	Belongs to the SlyX family
ET951_RS04045	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ET951_RS04050	COG0330	HflC and HflK could
ET951_RS04055	COG0330	HflC and HflK could
ET951_RS04060	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ET951_RS04065	COG1923	regulation of RNA biosynthetic process
ET951_RS04070	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ET951_RS04075	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ET951_RS04085	COG0802	atpase or kinase
ET951_RS04090	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ET951_RS04140	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ET951_RS04145	COG1162	GTPase activity
ET951_RS04150	COG0688	phosphatidylethanolamine metabolic process
ET951_RS04155	COG0471	metal ion transport
ET951_RS04165	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ET951_RS04170	COG4942	peptidase
ET951_RS04185	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ET951_RS04190	COG2816	NAD+ diphosphatase activity
ET951_RS04195	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ET951_RS04200	COG3344	reverse transcriptase
ET951_RS04205	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ET951_RS04210	COG0085	RNA polymerase activity
ET951_RS04215	COG0222	ribosome binding
ET951_RS04220	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ET951_RS04230	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ET951_RS04235	COG0250	Participates in transcription elongation, termination and antitermination
ET951_RS04240	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ET951_RS04245	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ET951_RS04270	COG1072	(Pantothenic acid kinase))
ET951_RS04280	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ET951_RS04290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ET951_RS04340	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ET951_RS04355	COG3118	belongs to the thioredoxin family
ET951_RS04360	COG0513	Belongs to the DEAD box helicase family
ET951_RS04365	COG0248	Ppx GppA phosphatase
ET951_RS04375	COG2814	Major facilitator Superfamily
ET951_RS04390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ET951_RS04395	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ET951_RS04400	COG0511	ligase activity, forming carbon-carbon bonds
ET951_RS04405	COG0439	Biotin carboxylase
ET951_RS04415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ET951_RS04420	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ET951_RS04425	COG1609	Transcriptional regulator
ET951_RS04435	COG3265	gluconokinase activity
ET951_RS04440	COG2610	gluconate transmembrane transporter activity
ET951_RS04445	COG0800	Aldolase
ET951_RS04460	COG0840	transmembrane signaling receptor activity
ET951_RS04465	COG1982	Orn Lys Arg decarboxylase major
ET951_RS04470	COG0531	amino acid
ET951_RS04475	COG3710	Transcriptional regulator
ET951_RS04480	COG0789	Transcriptional regulator
ET951_RS04495	COG0151	Belongs to the GarS family
ET951_RS04505	COG0776	regulation of translation
ET951_RS04510	COG1253	flavin adenine dinucleotide binding
ET951_RS04515	COG3068	Protein conserved in bacteria
ET951_RS04525	COG1573	uracil-dna glycosylase
ET951_RS04530	COG0668	transmembrane transport
ET951_RS04535	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ET951_RS04545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ET951_RS04550	COG0438	transferase activity, transferring glycosyl groups
ET951_RS04590	COG1596	polysaccharide export
ET951_RS04610	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ET951_RS04625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ET951_RS04650	COG1086	Polysaccharide biosynthesis protein
ET951_RS04715	COG1028	Short-chain dehydrogenase reductase Sdr
ET951_RS04720	COG1083	cytidylyl-transferase
ET951_RS04725	COG0673	inositol 2-dehydrogenase activity
ET951_RS04740	COG2089	acid synthase
ET951_RS04750	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ET951_RS04760	COG2030	dehydratase
ET951_RS04765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ET951_RS04780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ET951_RS04815	COG1519	Transferase
ET951_RS04840	COG3642	lipopolysaccharide core region biosynthetic process
ET951_RS04845	COG0859	PFAM glycosyl transferase family 9
ET951_RS04850	COG0463	Glycosyl transferase, family 2
ET951_RS04855	COG0859	PFAM glycosyl transferase family 9
ET951_RS04860	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ET951_RS04865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ET951_RS04875	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ET951_RS04880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ET951_RS04885	COG2003	Belongs to the UPF0758 family
ET951_RS04895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ET951_RS04900	COG1309	transcriptional regulator
ET951_RS04905	COG1560	Kdo2-lipid A biosynthetic process
ET951_RS04910	COG1560	Kdo2-lipid A biosynthetic process
ET951_RS04915	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ET951_RS04920	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ET951_RS04925	COG1561	YicC-like family, N-terminal region
ET951_RS04930	COG2862	Uncharacterized protein family, UPF0114
ET951_RS04935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET951_RS04935	COG1263	PTS System
ET951_RS04940	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ET951_RS04955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET951_RS04960	COG1120	ATPase activity
ET951_RS04965	COG4774	siderophore transport
ET951_RS04980	COG0514	ATP-dependent DNA helicase (RecQ)
ET951_RS04985	COG2962	Rard protein
ET951_RS05000	COG1280	lysine exporter protein (LysE YggA)
ET951_RS05005	COG0210	DNA helicase
ET951_RS05015	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ET951_RS05020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ET951_RS05030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET951_RS05035	COG0601	transmembrane transport
ET951_RS05040	COG0747	negative chemotaxis
ET951_RS05085	COG1309	transcriptional regulator
ET951_RS05090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ET951_RS05095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ET951_RS05100	COG2960	long-chain fatty acid transporting porin activity
ET951_RS05105	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ET951_RS05110	COG0583	DNA-binding transcription factor activity
ET951_RS05180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ET951_RS05185	COG1739	Uncharacterized protein family UPF0029
ET951_RS05190	COG1024	Enoyl-CoA hydratase
ET951_RS05190	COG1250	3-hydroxyacyl-CoA dehydrogenase
ET951_RS05195	COG0183	Belongs to the thiolase family
ET951_RS05200	COG0583	DNA-binding transcription factor activity
ET951_RS05205	COG2814	Major facilitator Superfamily
ET951_RS05215	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ET951_RS05220	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ET951_RS05225	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ET951_RS05230	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ET951_RS05235	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ET951_RS05240	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ET951_RS05250	COG0356	it plays a direct role in the translocation of protons across the membrane
ET951_RS05255	COG3312	ion transport
ET951_RS05260	COG1475	DNA binding
ET951_RS05265	COG1192	Involved in chromosome partitioning
ET951_RS05270	COG0357	Ribosomal RNA small subunit methyltransferase G
ET951_RS05275	COG0445	tRNA wobble uridine modification
ET951_RS05280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ET951_RS05330	COG0210	DNA helicase
ET951_RS05430	COG4974	Belongs to the 'phage' integrase family
ET951_RS05435	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ET951_RS05440	COG0706	membrane insertase activity
ET951_RS05450	COG0594	ribonuclease P activity
ET951_RS05455	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ET951_RS05460	COG1126	abc transporter atp-binding protein
ET951_RS05475	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ET951_RS05480	COG0592	DNA-directed DNA polymerase activity
ET951_RS05485	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ET951_RS05490	COG0187	DNA topoisomerase II activity
ET951_RS05505	COG0071	Belongs to the small heat shock protein (HSP20) family
ET951_RS05510	COG3977	Valine--pyruvate aminotransferase
ET951_RS05515	COG0751	glycine-tRNA ligase activity
ET951_RS05520	COG0752	glycyl-tRNA synthetase alpha subunit
ET951_RS05525	COG2119	membrane
ET951_RS05535	COG0425	Belongs to the sulfur carrier protein TusA family
ET951_RS05550	COG0604	alcohol dehydrogenase
ET951_RS05560	COG0129	dihydroxy-acid dehydratase activity
ET951_RS05565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ET951_RS05580	COG0606	chelatase, subunit chli
ET951_RS05585	COG0204	Acyl-transferase
ET951_RS05590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ET951_RS05595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ET951_RS05605	COG3084	Protein conserved in bacteria
ET951_RS05615	COG4326	sporulation control protein
ET951_RS05620	COG1272	protein, Hemolysin III
ET951_RS05630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ET951_RS05635	COG0569	domain protein
ET951_RS05640	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ET951_RS05640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ET951_RS05650	COG0242	peptide deformylase activity
ET951_RS05655	COG1652	LysM domain
ET951_RS05660	COG0758	DNA mediated transformation
ET951_RS05665	COG2922	Belongs to the Smg family
ET951_RS05670	COG0551	DNA topoisomerase type I activity
ET951_RS05675	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ET951_RS05680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ET951_RS05685	COG0009	L-threonylcarbamoyladenylate synthase
ET951_RS05695	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ET951_RS05705	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ET951_RS05745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ET951_RS05750	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ET951_RS05760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ET951_RS05765	COG2104	thiamine diphosphate biosynthetic process
ET951_RS05770	COG2022	thiamine diphosphate biosynthetic process
ET951_RS05775	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ET951_RS05780	COG0006	proline dipeptidase activity
ET951_RS05780	COG0006	proline dipeptidase activity
ET951_RS05800	COG1522	sequence-specific DNA binding
ET951_RS05805	COG5002	protein histidine kinase activity
ET951_RS05805	COG5001	Diguanylate cyclase
ET951_RS05825	COG0589	response to stress
ET951_RS05835	COG1528	Iron-storage protein
ET951_RS05845	COG2081	HI0933 family
ET951_RS05850	COG0840	transmembrane signaling receptor activity
ET951_RS05860	COG1322	Protein conserved in bacteria
ET951_RS05865	COG2226	methyltransferase
ET951_RS05880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ET951_RS05885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ET951_RS05890	COG0805	protein transport
ET951_RS05895	COG0534	Mate efflux family protein
ET951_RS05905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ET951_RS05910	COG2937	Belongs to the GPAT DAPAT family
ET951_RS05915	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ET951_RS05920	COG3161	chorismate lyase activity
ET951_RS05930	COG1580	Controls the rotational direction of flagella during chemotaxis
ET951_RS05940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ET951_RS05945	COG0084	hydrolase, TatD family'
ET951_RS05960	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ET951_RS05960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ET951_RS05980	COG3078	GTPase activator activity
ET951_RS05995	COG3344	reverse transcriptase
ET951_RS06000	COG3071	HemY protein
ET951_RS06005	COG2959	enzyme of heme biosynthesis
ET951_RS06010	COG1587	Uroporphyrinogen-III synthase
ET951_RS06015	COG0181	hydroxymethylbilane synthase activity
ET951_RS06025	COG3072	Adenylate cyclase
ET951_RS06030	COG1965	Belongs to the frataxin family
ET951_RS06040	COG0019	diaminopimelate decarboxylase activity
ET951_RS06045	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ET951_RS06055	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ET951_RS06060	COG1011	Hydrolase
ET951_RS06065	COG2199	diguanylate cyclase activity
ET951_RS06065	COG2200	EAL domain
ET951_RS06065	COG3287	FIST C domain
ET951_RS06080	COG0561	phosphatase activity
ET951_RS06085	COG2267	carboxylic ester hydrolase activity
ET951_RS06090	COG1280	lysine exporter protein (LysE YggA)
ET951_RS06095	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ET951_RS06100	COG0783	Belongs to the Dps family
ET951_RS06135	COG0742	ribosomal rna small subunit methyltransferase
ET951_RS06140	COG0552	protein localization to endoplasmic reticulum
ET951_RS06145	COG2884	Cell division ATP-binding protein ftsE
ET951_RS06150	COG2177	Part of the ABC transporter FtsEX involved in
ET951_RS06155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ET951_RS06160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ET951_RS06175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ET951_RS06180	COG4206	TonB-dependent receptor
ET951_RS06190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ET951_RS06260	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ET951_RS06265	COG3300	MHYT domain
ET951_RS06265	COG5001	Diguanylate cyclase
ET951_RS06275	COG3852	Histidine kinase
ET951_RS06285	COG0174	glutamine synthetase
ET951_RS06295	COG1217	gtp-binding protein TYPA
ET951_RS06305	COG1295	ribonuclease BN
ET951_RS06310	COG1490	D-aminoacyl-tRNA deacylase activity
ET951_RS06315	COG0456	acetyltransferase
ET951_RS06325	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ET951_RS06330	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ET951_RS06335	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ET951_RS06340	COG3031	protein transport across the cell outer membrane
ET951_RS06350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ET951_RS06355	COG1459	type II secretion system
ET951_RS06360	COG2165	general secretion pathway protein
ET951_RS06365	COG2165	general secretion pathway protein
ET951_RS06370	COG2165	general secretion pathway protein
ET951_RS06375	COG4795	General secretion pathway protein
ET951_RS06380	COG3156	type II secretion system protein K
ET951_RS06385	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ET951_RS06390	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ET951_RS06405	COG0494	nUDIX hydrolase
ET951_RS06415	COG1040	competence protein
ET951_RS06420	COG0596	Alpha beta hydrolase
ET951_RS06430	COG2183	response to ionizing radiation
ET951_RS06435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ET951_RS06440	COG2197	response regulator
ET951_RS06450	COG1129	ABC transporter
ET951_RS06455	COG1172	Belongs to the binding-protein-dependent transport system permease family
ET951_RS06460	COG1472	Belongs to the glycosyl hydrolase 3 family
ET951_RS06480	COG2233	PERMEase
ET951_RS06485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ET951_RS06490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ET951_RS06495	COG1758	RNA polymerase activity
ET951_RS06500	COG0194	GDP metabolic process
ET951_RS06505	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ET951_RS06510	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ET951_RS06530	COG4232	protein-disulfide reductase activity
ET951_RS06535	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ET951_RS06540	COG1027	Aspartate ammonia-lyase
ET951_RS06550	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ET951_RS06560	COG2205	protein histidine kinase activity
ET951_RS06565	COG0745	RESPONSE REGULATOR receiver
ET951_RS06575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ET951_RS06580	COG0205	6-phosphofructokinase activity
ET951_RS06585	COG1494	fructose-1,6-bisphosphatase
ET951_RS06590	COG3074	FtsZ-dependent cytokinesis
ET951_RS06595	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ET951_RS06600	COG0527	aspartate kinase activity
ET951_RS06600	COG0460	homoserine dehydrogenase
ET951_RS06605	COG0626	cystathionine gamma-synthase activity
ET951_RS06610	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
ET951_RS06620	COG0281	malic enzyme
ET951_RS06625	COG0254	rRNA binding
ET951_RS06630	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ET951_RS06635	COG1609	Transcriptional regulator
ET951_RS06645	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ET951_RS06650	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ET951_RS06655	COG1575	Belongs to the MenA family. Type 1 subfamily
ET951_RS06660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ET951_RS06665	COG0534	Mate efflux family protein
ET951_RS06670	COG0149	triose-phosphate isomerase activity
ET951_RS06695	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ET951_RS06700	COG0459	protein refolding
ET951_RS06705	COG3344	reverse transcriptase
ET951_RS06715	COG1509	lysine 2,3-aminomutase activity
ET951_RS06720	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ET951_RS06730	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ET951_RS06735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ET951_RS06740	COG1053	succinate dehydrogenase
ET951_RS06745	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ET951_RS06750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ET951_RS06755	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ET951_RS06760	COG3344	reverse transcriptase
ET951_RS06765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ET951_RS06770	COG1045	serine acetyltransferase
ET951_RS06780	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ET951_RS06785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ET951_RS06790	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ET951_RS06795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ET951_RS06800	COG0137	argininosuccinate synthase activity
ET951_RS06805	COG0165	Argininosuccinate lyase
ET951_RS06815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ET951_RS06820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ET951_RS06820	COG0678	peroxiredoxin activity
ET951_RS06830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ET951_RS06860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ET951_RS06865	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ET951_RS06875	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ET951_RS06880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ET951_RS06885	COG0546	phosphoglycolate phosphatase activity
ET951_RS06890	COG0180	Tryptophanyl-tRNA synthetase
ET951_RS06905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ET951_RS06915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ET951_RS06925	COG1012	belongs to the aldehyde dehydrogenase family
ET951_RS06940	COG3954	Phosphoribulokinase
ET951_RS06950	COG0429	hydrolase of the alpha beta-hydrolase fold
ET951_RS06960	COG0488	(ABC) transporter
ET951_RS06965	COG2249	NAD(P)H dehydrogenase (quinone) activity
ET951_RS06980	COG1047	Peptidyl-prolyl cis-trans
ET951_RS06995	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ET951_RS07000	COG3083	sulfuric ester hydrolase activity
ET951_RS07005	COG0557	exoribonuclease II activity
ET951_RS07010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ET951_RS07015	COG0051	transcription antitermination factor activity, RNA binding
ET951_RS07020	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ET951_RS07025	COG0088	Forms part of the polypeptide exit tunnel
ET951_RS07030	COG0089	rRNA binding
ET951_RS07035	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ET951_RS07040	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ET951_RS07045	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ET951_RS07050	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ET951_RS07055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ET951_RS07060	COG0255	Belongs to the universal ribosomal protein uL29 family
ET951_RS07065	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ET951_RS07070	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ET951_RS07075	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ET951_RS07080	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ET951_RS07085	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ET951_RS07090	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ET951_RS07100	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ET951_RS07105	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ET951_RS07110	COG1841	ribosomal large subunit assembly
ET951_RS07120	COG0201	protein transport
ET951_RS07125	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ET951_RS07130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ET951_RS07135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ET951_RS07140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ET951_RS07145	COG0202	RNA polymerase activity
ET951_RS07150	COG0203	ribosomal protein L17
ET951_RS07160	COG0545	Peptidyl-prolyl cis-trans isomerase
ET951_RS07165	COG3061	Opacity-associated protein A
ET951_RS07170	COG0697	spore germination
ET951_RS07175	COG2153	protein acetylation
ET951_RS07180	COG0513	Belongs to the DEAD box helicase family
ET951_RS07190	COG0737	Belongs to the 5'-nucleotidase family
ET951_RS07195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ET951_RS07195	COG1648	precorrin-2 dehydrogenase activity
ET951_RS07200	COG0175	sulfate reduction
ET951_RS07205	COG2895	sulfate adenylyltransferase (ATP) activity
ET951_RS07210	COG0529	Catalyzes the synthesis of activated sulfate
ET951_RS07230	COG1136	(ABC) transporter
ET951_RS07245	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ET951_RS07250	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ET951_RS07255	COG0729	surface antigen
ET951_RS07260	COG2911	Protein conserved in bacteria
ET951_RS07265	COG2105	PFAM AIG2 family protein
ET951_RS07275	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ET951_RS07280	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ET951_RS07285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ET951_RS07290	COG0163	prenyltransferase activity
ET951_RS07300	COG1178	ABC-type Fe3 transport system permease component
ET951_RS07305	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ET951_RS07310	COG3028	Belongs to the UPF0307 family
ET951_RS07315	COG0312	modulator of DNA gyrase
ET951_RS07320	COG2239	Acts as a magnesium transporter
ET951_RS07325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET951_RS07330	COG1660	Displays ATPase and GTPase activities
ET951_RS07335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET951_RS07340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ET951_RS07350	COG1137	ATPase activity
ET951_RS07355	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ET951_RS07370	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ET951_RS07370	COG0517	IMP dehydrogenase activity
ET951_RS07380	COG1127	ABC transporter
ET951_RS07385	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ET951_RS07390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ET951_RS07395	COG2854	intermembrane phospholipid transfer
ET951_RS07405	COG5007	Belongs to the BolA IbaG family
ET951_RS07410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ET951_RS07415	COG0204	Acyl-transferase
ET951_RS07420	COG0251	oxidation-reduction process
ET951_RS07430	COG0540	Belongs to the ATCase OTCase family
ET951_RS07440	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ET951_RS07445	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ET951_RS07450	COG0564	pseudouridine synthase activity
ET951_RS07455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ET951_RS07460	COG4269	membrane
ET951_RS07470	COG0525	valine-tRNA ligase activity
ET951_RS07475	COG2927	DNA polymerase III (CHI subunit)
ET951_RS07480	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ET951_RS07485	COG0795	lipopolysaccharide-transporting ATPase activity
ET951_RS07490	COG0795	lipopolysaccharide-transporting ATPase activity
ET951_RS07505	COG3437	response regulator, receiver
ET951_RS07550	COG0066	3-isopropylmalate dehydratase activity
ET951_RS07555	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ET951_RS07560	COG0473	3-isopropylmalate dehydrogenase activity
ET951_RS07575	COG0671	phosphoesterase, PA-phosphatase related
ET951_RS07585	COG0583	DNA-binding transcription factor activity
ET951_RS07590	COG1022	Amp-dependent synthetase and ligase
ET951_RS07595	COG0028	Belongs to the TPP enzyme family
ET951_RS07600	COG0440	acetolactate synthase activity
ET951_RS07605	COG3344	reverse transcriptase
ET951_RS07610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ET951_RS07615	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ET951_RS07620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ET951_RS07630	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ET951_RS07635	COG3079	Belongs to the UPF0149 family
ET951_RS07640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ET951_RS07645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ET951_RS07660	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ET951_RS07670	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ET951_RS07675	COG1595	DNA-templated transcription, initiation
ET951_RS07690	COG3086	response to oxidative stress
ET951_RS07695	COG0481	GTPase activity
ET951_RS07705	COG0571	ribonuclease III activity
ET951_RS07710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ET951_RS07715	COG1381	Involved in DNA repair and RecF pathway recombination
ET951_RS07720	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ET951_RS07725	COG0736	holo-[acyl-carrier-protein] synthase activity
ET951_RS07740	COG5001	Diguanylate cyclase
ET951_RS07745	COG3437	response regulator, receiver
ET951_RS07745	COG3850	Histidine kinase
ET951_RS07745	COG4999	Histidine kinase
ET951_RS07745	COG2205	protein histidine kinase activity
ET951_RS07755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ET951_RS07760	COG3956	TIGRFAM MazG family protein
ET951_RS07765	COG0504	CTP synthase activity
ET951_RS07770	COG0148	phosphopyruvate hydratase activity
ET951_RS07775	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ET951_RS07780	COG0814	amino acid
ET951_RS07790	COG0617	tRNA 3'-terminal CCA addition
ET951_RS07805	COG4991	sh3 domain protein
ET951_RS07810	COG0306	phosphate transporter
ET951_RS07815	COG1392	Phosphate transport regulator
ET951_RS07820	COG3025	triphosphatase activity
ET951_RS07825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ET951_RS07835	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ET951_RS07845	COG1538	Outer membrane efflux protein
ET951_RS07850	COG0494	nUDIX hydrolase
ET951_RS07855	COG3151	Protein conserved in bacteria
ET951_RS07865	COG3150	esterase
ET951_RS07870	COG0187	DNA topoisomerase II activity
ET951_RS07875	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ET951_RS07885	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
ET951_RS07890	COG0237	dephospho-CoA kinase activity
ET951_RS07900	COG1459	type II secretion system
ET951_RS07905	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ET951_RS07915	COG0157	Belongs to the NadC ModD family
ET951_RS07925	COG0716	FMN binding
ET951_RS07930	COG4974	Belongs to the 'phage' integrase family
ET951_RS07935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ET951_RS07940	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ET951_RS07945	COG1227	inorganic diphosphatase activity
ET951_RS07950	COG0737	Belongs to the 5'-nucleotidase family
ET951_RS07960	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ET951_RS07965	COG0508	dehydrogenase complex catalyzes the overall conversion of
ET951_RS07970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ET951_RS07985	COG3116	cell division
ET951_RS07990	COG0768	penicillin binding
ET951_RS07995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ET951_RS08000	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ET951_RS08010	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ET951_RS08015	COG0772	Belongs to the SEDS family
ET951_RS08020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ET951_RS08025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ET951_RS08030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ET951_RS08035	COG0849	cell division
ET951_RS08040	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ET951_RS08045	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ET951_RS08055	COG0653	protein targeting
ET951_RS08060	COG0494	nUDIX hydrolase
ET951_RS08065	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ET951_RS08070	COG0505	Belongs to the CarA family
ET951_RS08075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ET951_RS08080	COG0730	response to heat
ET951_RS08085	COG0583	DNA-binding transcription factor activity
ET951_RS08090	COG2860	membrane
ET951_RS08095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ET951_RS08105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ET951_RS08115	COG0493	'glutamate synthase
ET951_RS08120	COG0069	glutamate synthase activity
ET951_RS08120	COG0070	glutamate synthase
ET951_RS08120	COG0067	glutamate synthase
ET951_RS08130	COG0070	glutamate synthase
ET951_RS08130	COG0069	glutamate synthase activity
ET951_RS08130	COG0067	glutamate synthase
ET951_RS08135	COG1242	4 iron, 4 sulfur cluster binding
ET951_RS08140	COG2203	Gaf domain
ET951_RS08140	COG3706	GGDEF domain
ET951_RS08140	COG4251	negative regulation of phosphorylation
ET951_RS08140	COG5001	Diguanylate cyclase
ET951_RS08145	COG5002	protein histidine kinase activity
ET951_RS08145	COG2198	Histidine kinase
ET951_RS08145	COG0784	Response regulator, receiver
ET951_RS08150	COG0745	RESPONSE REGULATOR receiver
ET951_RS08160	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ET951_RS08180	COG0083	homoserine kinase activity
ET951_RS08185	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ET951_RS08190	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
ET951_RS08195	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ET951_RS08200	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ET951_RS08215	COG1115	amino acid carrier protein
ET951_RS08220	COG3022	response to hydroperoxide
ET951_RS08225	COG0084	hydrolase, TatD family'
ET951_RS08230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ET951_RS08240	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ET951_RS08245	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ET951_RS08250	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ET951_RS08255	COG0813	purine-nucleoside phosphorylase activity
ET951_RS08265	COG0560	Phosphoserine phosphatase
ET951_RS08275	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ET951_RS08280	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ET951_RS08285	COG0583	DNA-binding transcription factor activity
ET951_RS08310	COG3250	beta-galactosidase activity
ET951_RS08315	COG1609	Transcriptional regulator
ET951_RS08320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ET951_RS08335	COG0569	domain protein
ET951_RS08335	COG0189	ligase activity
ET951_RS08350	COG2171	N-acyltransferase activity
ET951_RS08355	COG3141	response to X-ray
ET951_RS08370	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ET951_RS08375	COG1074	ATP-dependent DNA helicase activity
ET951_RS08380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ET951_RS08390	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ET951_RS08390	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ET951_RS08400	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ET951_RS08405	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ET951_RS08410	COG2166	iron-sulfur cluster assembly
ET951_RS08415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ET951_RS08420	COG0693	protein deglycase activity
ET951_RS08425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ET951_RS08440	COG1595	DNA-templated transcription, initiation
ET951_RS08450	COG2211	Major facilitator Superfamily
ET951_RS08465	COG2813	Specifically methylates the guanine in position
ET951_RS08470	COG0271	Belongs to the BolA IbaG family
ET951_RS08475	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ET951_RS08480	COG1805	sodium ion transport
ET951_RS08485	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ET951_RS08490	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ET951_RS08495	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ET951_RS08500	COG2871	sodium ion transport
ET951_RS08505	COG1477	protein flavinylation
ET951_RS08525	COG3706	GGDEF domain
ET951_RS08525	COG2203	Gaf domain
ET951_RS08525	COG4251	negative regulation of phosphorylation
ET951_RS08525	COG5001	Diguanylate cyclase
ET951_RS08530	COG0733	neurotransmitter:sodium symporter activity
ET951_RS08540	COG0189	ligase activity
ET951_RS08545	COG0189	ligase activity
ET951_RS08545	COG4067	protein conserved in archaea
ET951_RS08550	COG2195	Cleaves the N-terminal amino acid of tripeptides
ET951_RS08555	COG2252	PERMEase
ET951_RS08560	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ET951_RS08565	COG1073	alpha beta
ET951_RS08575	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ET951_RS08580	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ET951_RS08585	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ET951_RS08590	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ET951_RS08590	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ET951_RS08605	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ET951_RS08610	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ET951_RS08615	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ET951_RS08620	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ET951_RS08630	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ET951_RS08635	COG0024	Methionine aminopeptidase
ET951_RS08640	COG0052	Belongs to the universal ribosomal protein uS2 family
ET951_RS08645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ET951_RS08650	COG0528	UMP kinase activity
ET951_RS08655	COG0233	cytoplasmic translational termination
ET951_RS08660	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ET951_RS08665	COG0575	Belongs to the CDS family
ET951_RS08670	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ET951_RS08675	COG0750	zinc metalloprotease
ET951_RS08685	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ET951_RS08690	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ET951_RS08695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ET951_RS08700	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ET951_RS08705	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ET951_RS08710	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ET951_RS08715	COG0587	DNA-directed DNA polymerase activity
ET951_RS08720	COG0825	malonyl-CoA metabolic process
ET951_RS08725	COG0037	tRNA processing
ET951_RS08735	COG0347	Belongs to the P(II) protein family
ET951_RS08740	COG3021	interspecies interaction between organisms
ET951_RS08745	COG0741	lytic transglycosylase activity
ET951_RS08745	COG1388	LysM domain
ET951_RS08750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ET951_RS08755	COG2226	methyltransferase
ET951_RS08760	COG0328	RNA-DNA hybrid ribonuclease activity
ET951_RS08775	COG1960	acyl-CoA dehydrogenase activity
ET951_RS08780	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ET951_RS08785	COG0121	glutamine amidotransferase
ET951_RS08790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ET951_RS08795	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ET951_RS08800	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ET951_RS08805	COG1187	pseudouridine synthase activity
ET951_RS08810	COG2840	Smr protein MutS2
ET951_RS08840	COG2217	Heavy metal translocating P-type atpase
ET951_RS08840	COG2608	mercury ion transmembrane transporter activity
ET951_RS08845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ET951_RS08895	COG0835	chemotaxis
ET951_RS08895	COG0784	Response regulator, receiver
ET951_RS08900	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ET951_RS08905	COG1815	bacterial-type flagellum-dependent cell motility
ET951_RS08920	COG1749	Flagellar hook protein flgE
ET951_RS08925	COG4787	bacterial-type flagellum-dependent cell motility
ET951_RS08935	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ET951_RS08940	COG1706	bacterial-type flagellum-dependent cell motility
ET951_RS08945	COG3951	Flagellar rod assembly protein muramidase FlgJ
ET951_RS08945	COG1705	Flagellar rod assembly protein muramidase FlgJ
ET951_RS08960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ET951_RS08965	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ET951_RS09050	COG0012	GTP binding
ET951_RS09055	COG0193	aminoacyl-tRNA hydrolase activity
ET951_RS09060	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ET951_RS09070	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ET951_RS09075	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ET951_RS09080	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ET951_RS09085	COG2890	protein-(glutamine-N5) methyltransferase activity
ET951_RS09095	COG2912	Transglutaminase-like superfamily
ET951_RS09100	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ET951_RS09105	COG0737	Belongs to the 5'-nucleotidase family
ET951_RS09110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ET951_RS09115	COG2233	PERMEase
ET951_RS09135	COG1393	Belongs to the ArsC family
ET951_RS09140	COG4783	chaperone-mediated protein folding
ET951_RS09160	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ET951_RS09175	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ET951_RS09185	COG1876	peptidase activity
ET951_RS09195	COG1393	Belongs to the ArsC family
ET951_RS09215	COG2837	iron assimilation
ET951_RS09220	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ET951_RS09225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ET951_RS09230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ET951_RS09235	COG1334	flagellar protein FlaG
ET951_RS09240	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ET951_RS09250	COG1516	flagellar protein fliS
ET951_RS09270	COG1677	Flagellar hook-basal body complex protein FliE
ET951_RS09280	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ET951_RS09285	COG1317	bacterial-type flagellum organization
ET951_RS09330	COG1987	bacterial-type flagellum assembly
ET951_RS09345	COG2840	Smr protein MutS2
ET951_RS09350	COG2890	protein-(glutamine-N5) methyltransferase activity
ET951_RS09355	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ET951_RS09360	COG2860	membrane
ET951_RS09365	COG3101	peptidyl-lysine hydroxylation
ET951_RS09375	COG0431	NADPH-dependent FMN reductase
ET951_RS09380	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ET951_RS09380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ET951_RS09385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ET951_RS09390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ET951_RS09395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ET951_RS09400	COG0735	belongs to the Fur family
ET951_RS09410	COG0583	DNA-binding transcription factor activity
ET951_RS09420	COG1346	cytolysis
ET951_RS09435	COG0596	Alpha beta hydrolase
ET951_RS09440	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ET951_RS09445	COG0033	Phosphoglucomutase
ET951_RS09455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ET951_RS09460	COG0372	Belongs to the citrate synthase family
ET951_RS09470	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ET951_RS09475	COG1053	succinate dehydrogenase
ET951_RS09485	COG0567	Dehydrogenase, E1 component
ET951_RS09490	COG0508	dehydrogenase complex catalyzes the overall conversion of
ET951_RS09495	COG0045	succinate-CoA ligase (ADP-forming) activity
ET951_RS09505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ET951_RS09510	COG1121	(ABC) transporter
ET951_RS09515	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ET951_RS09520	COG4977	sequence-specific DNA binding
ET951_RS09525	COG1918	ferrous iron import across plasma membrane
ET951_RS09550	COG0018	arginyl-trna synthetase
ET951_RS09560	COG1025	Belongs to the peptidase M16 family
ET951_RS09565	COG2062	phosphohistidine phosphatase, SixA
ET951_RS09595	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ET951_RS09600	COG0784	Response regulator, receiver
ET951_RS09600	COG0643	Histidine kinase
ET951_RS09600	COG2198	Histidine kinase
ET951_RS09605	COG2201	protein-glutamate methylesterase activity
ET951_RS09610	COG1192	Involved in chromosome partitioning
ET951_RS09620	COG0835	chemotaxis
ET951_RS09630	COG4133	protoheme IX ABC transporter activity
ET951_RS09635	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ET951_RS09640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ET951_RS09650	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ET951_RS09655	COG1138	Cytochrome C-type biogenesis protein
ET951_RS09660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ET951_RS09665	COG4235	cytochrome complex assembly
ET951_RS09665	COG3088	subunit of a heme lyase
ET951_RS09675	COG2853	Lipoprotein
ET951_RS09695	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ET951_RS09700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ET951_RS09705	COG0123	including yeast histone deacetylase and acetoin utilization protein
ET951_RS09720	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ET951_RS09740	COG3083	sulfuric ester hydrolase activity
ET951_RS09745	COG3082	Protein of unknown function (DUF1414)
ET951_RS09750	COG3081	Nucleoid-associated protein
ET951_RS09760	COG1757	Na H antiporter
ET951_RS09765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ET951_RS09770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ET951_RS09775	COG2095	MarC family integral membrane protein
ET951_RS09780	COG1454	alcohol dehydrogenase
ET951_RS09780	COG1012	belongs to the aldehyde dehydrogenase family
ET951_RS09785	COG3344	reverse transcriptase
ET951_RS09795	COG0659	secondary active sulfate transmembrane transporter activity
ET951_RS09800	COG1530	ribonuclease E activity
ET951_RS09805	COG0564	pseudouridine synthase activity
ET951_RS09810	COG0424	maF-like protein
ET951_RS09815	COG1399	metal-binding, possibly nucleic acid-binding protein
ET951_RS09820	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ET951_RS09825	COG0416	fatty acid biosynthetic process
ET951_RS09830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ET951_RS09840	COG1028	Short-chain dehydrogenase reductase Sdr
ET951_RS09845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ET951_RS09850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ET951_RS09855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ET951_RS09860	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ET951_RS09865	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ET951_RS09870	COG0470	DNA polymerase III
ET951_RS09875	COG0084	hydrolase, TatD family'
ET951_RS09880	COG1263	PTS System
ET951_RS09880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET951_RS09895	COG0733	neurotransmitter:sodium symporter activity
ET951_RS09910	COG4667	esterase of the alpha-beta hydrolase superfamily
ET951_RS09920	COG1940	carbohydrate kinase activity
ET951_RS09925	COG0784	Response regulator, receiver
ET951_RS09925	COG0835	chemotaxis
ET951_RS09955	COG2226	methyltransferase
ET951_RS09970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ET951_RS09975	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ET951_RS09985	COG3139	Protein of unknown function (DUF1315)
ET951_RS09990	COG0252	asparaginase activity
ET951_RS09995	COG0616	signal peptide processing
ET951_RS10000	COG1902	pentaerythritol trinitrate reductase activity
ET951_RS10000	COG0446	pyridine nucleotide-disulphide oxidoreductase
ET951_RS10005	COG3344	reverse transcriptase
ET951_RS10010	COG0788	formyltetrahydrofolate deformylase activity
ET951_RS10020	COG1199	ATP-dependent helicase activity
ET951_RS10025	COG1214	PFAM Peptidase M22, glycoprotease
ET951_RS10040	COG0596	Alpha beta hydrolase
ET951_RS10045	COG0318	PFAM AMP-dependent synthetase and ligase
ET951_RS10050	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ET951_RS10070	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ET951_RS10075	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ET951_RS10080	COG0436	Aminotransferase
ET951_RS10085	COG1169	isochorismate synthase
ET951_RS10090	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ET951_RS10095	COG0596	Alpha beta hydrolase
ET951_RS10115	COG3135	benzoate transporter
ET951_RS10120	COG1396	sequence-specific DNA binding
ET951_RS10130	COG0477	Major facilitator Superfamily
ET951_RS10150	COG3015	lipoprotein NlpE involved in copper resistance
ET951_RS10155	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ET951_RS10160	COG2894	cell division
ET951_RS10165	COG0850	regulation of cytokinetic process
ET951_RS10175	COG3100	YcgL domain-containing protein
ET951_RS10180	COG2951	lytic endotransglycosylase activity
ET951_RS10190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ET951_RS10195	COG3325	Belongs to the glycosyl hydrolase 18 family
ET951_RS10195	COG3469	chitinase activity
ET951_RS10205	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ET951_RS10225	COG0671	phosphoesterase, PA-phosphatase related
ET951_RS10245	COG4589	Belongs to the CDS family
ET951_RS10255	COG3300	MHYT domain
ET951_RS10255	COG5001	Diguanylate cyclase
ET951_RS10270	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ET951_RS10275	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ET951_RS10280	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ET951_RS10285	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ET951_RS10295	COG4191	Histidine kinase
ET951_RS10305	COG0544	peptidyl-prolyl cis-trans isomerase activity
ET951_RS10315	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ET951_RS10320	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ET951_RS10325	COG0776	regulation of translation
ET951_RS10330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ET951_RS10335	COG1555	photosystem II stabilization
ET951_RS10340	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ET951_RS10345	COG0539	negative regulation of cytoplasmic translation
ET951_RS10350	COG0776	regulation of translation
ET951_RS10355	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ET951_RS10360	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ET951_RS10380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ET951_RS10385	COG1215	transferase activity, transferring glycosyl groups
ET951_RS10390	COG0438	transferase activity, transferring glycosyl groups
ET951_RS10425	COG0438	transferase activity, transferring glycosyl groups
ET951_RS10435	COG2204	response regulator
ET951_RS10480	COG0601	transmembrane transport
ET951_RS10485	COG4239	(ABC) transporter, permease
ET951_RS10490	COG4166	transmembrane transport
ET951_RS10495	COG0444	Belongs to the ABC transporter superfamily
ET951_RS10500	COG4608	Belongs to the ABC transporter superfamily
ET951_RS10525	COG0583	DNA-binding transcription factor activity
ET951_RS10535	COG0686	Belongs to the AlaDH PNT family
ET951_RS10540	COG1522	sequence-specific DNA binding
ET951_RS10550	COG1674	ftsk spoiiie
ET951_RS10555	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ET951_RS10560	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ET951_RS10565	COG2186	Transcriptional regulator
ET951_RS10580	COG0537	adenosine 5'-monophosphoramidase activity
ET951_RS10605	COG3150	esterase
ET951_RS10610	COG1252	NADH dehydrogenase
ET951_RS10625	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ET951_RS10635	COG4591	ABC-type transport system involved in lipoprotein release permease component
ET951_RS10640	COG1136	(ABC) transporter
ET951_RS10645	COG4591	ABC-type transport system involved in lipoprotein release permease component
ET951_RS10655	COG2333	competence protein COMEC
ET951_RS10655	COG0658	competence protein
ET951_RS10660	COG1132	(ABC) transporter
ET951_RS10665	COG1663	tetraacyldisaccharide 4'-kinase activity
ET951_RS10670	COG2835	tetraacyldisaccharide 4'-kinase activity
ET951_RS10675	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ET951_RS10700	COG2719	SpoVR family
ET951_RS10705	COG2718	Belongs to the UPF0229 family
ET951_RS10710	COG2766	serine protein kinase
ET951_RS10715	COG3013	Belongs to the UPF0304 family
ET951_RS10725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ET951_RS10730	COG0840	transmembrane signaling receptor activity
ET951_RS10740	COG1882	Formate acetyltransferase
ET951_RS10765	COG4160	amino acid transport
ET951_RS10770	COG0708	Exodeoxyribonuclease III
ET951_RS10775	COG0840	transmembrane signaling receptor activity
ET951_RS10785	COG3923	Primosomal replication protein n
ET951_RS10790	COG0730	response to heat
ET951_RS10795	COG1199	ATP-dependent helicase activity
ET951_RS10805	COG3012	SEC-C Motif Domain Protein
ET951_RS10810	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ET951_RS10815	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ET951_RS10820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ET951_RS10825	COG0215	cysteine-tRNA ligase activity
ET951_RS10830	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ET951_RS10835	COG0632	four-way junction helicase activity
ET951_RS10845	COG1271	oxidase subunit
ET951_RS10850	COG1294	oxidase, subunit
ET951_RS10855	COG4890	Cyd operon protein YbgT
ET951_RS10865	COG0824	Thioesterase
ET951_RS10870	COG0811	peptide transport
ET951_RS10885	COG0823	Involved in the tonB-independent uptake of proteins
ET951_RS10890	COG2885	chlorophyll binding
ET951_RS10900	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ET951_RS10910	COG5002	protein histidine kinase activity
ET951_RS10910	COG0784	Response regulator, receiver
ET951_RS10925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ET951_RS10925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET951_RS10925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ET951_RS10930	COG2207	Transcriptional regulator
ET951_RS10940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ET951_RS10945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ET951_RS10950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ET951_RS10960	COG3537	Alpha-1,2-mannosidase
ET951_RS10975	COG3537	Alpha-1,2-mannosidase
ET951_RS10980	COG3537	Alpha-1,2-mannosidase
ET951_RS10985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ET951_RS11020	COG0583	DNA-binding transcription factor activity
ET951_RS11025	COG0641	radical SAM
ET951_RS11070	COG4964	Belongs to the GSP D family
ET951_RS11140	COG3069	C4-dicarboxylate transmembrane transporter activity
ET951_RS11145	COG2195	Cleaves the N-terminal amino acid of tripeptides
ET951_RS11155	COG2200	EAL domain
ET951_RS11155	COG2771	luxR family
ET951_RS11165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ET951_RS11170	COG1309	transcriptional regulator
ET951_RS11175	COG1012	belongs to the aldehyde dehydrogenase family
ET951_RS11195	COG1960	acyl-CoA dehydrogenase activity
ET951_RS11200	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ET951_RS11205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ET951_RS11215	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ET951_RS11230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ET951_RS11235	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ET951_RS11240	COG0297	glycogen (starch) synthase activity
ET951_RS11260	COG3070	regulator of competence-specific genes
ET951_RS11265	COG1609	Transcriptional regulator
ET951_RS11270	COG3381	protein complex oligomerization
ET951_RS11275	COG0745	RESPONSE REGULATOR receiver
ET951_RS11280	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ET951_RS11285	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ET951_RS11290	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
ET951_RS11295	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ET951_RS11315	COG1032	radical SAM domain protein
ET951_RS11320	COG2199	diguanylate cyclase activity
ET951_RS11320	COG2203	Gaf domain
ET951_RS11320	COG2200	EAL domain
ET951_RS11325	COG0612	Peptidase, M16
ET951_RS11340	COG0583	DNA-binding transcription factor activity
ET951_RS11345	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ET951_RS11355	COG2350	Protein conserved in bacteria
ET951_RS11360	COG1607	acyl-coa hydrolase
ET951_RS11380	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ET951_RS11385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ET951_RS11395	COG2116	formate transmembrane transporter activity
ET951_RS11400	COG4459	periplasmic nitrate reductase
ET951_RS11405	COG3005	denitrification pathway
ET951_RS11410	COG0243	molybdopterin cofactor binding
ET951_RS11420	COG1162	GTPase activity
ET951_RS11430	COG1227	inorganic diphosphatase activity
ET951_RS11445	COG4172	Belongs to the ABC transporter superfamily
ET951_RS11460	COG4168	peptide transport system, permease
ET951_RS11470	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ET951_RS11475	COG1842	Phage shock protein A
ET951_RS11490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ET951_RS11495	COG0519	Catalyzes the synthesis of GMP from XMP
ET951_RS11510	COG0733	neurotransmitter:sodium symporter activity
ET951_RS11515	COG0564	pseudouridine synthase activity
ET951_RS11520	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ET951_RS11525	COG4136	ATPase activity
ET951_RS11530	COG4135	transport system, permease component
ET951_RS11535	COG4134	Bacterial extracellular solute-binding protein
ET951_RS11545	COG3313	Fe-S protein
ET951_RS11555	COG0842	Transport permease protein
ET951_RS11560	COG1131	(ABC) transporter
ET951_RS11565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ET951_RS11570	COG0814	amino acid
ET951_RS11580	COG2239	Acts as a magnesium transporter
ET951_RS11585	COG0784	Response regulator, receiver
ET951_RS11585	COG2205	protein histidine kinase activity
ET951_RS11600	COG4934	collagen metabolic process
ET951_RS11620	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ET951_RS11650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ET951_RS11665	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ET951_RS11685	COG1061	Type III restriction enzyme res subunit
ET951_RS11690	COG1187	pseudouridine synthase activity
ET951_RS11695	COG2814	Major facilitator Superfamily
ET951_RS11705	COG0702	epimerase
ET951_RS11710	COG0534	Mate efflux family protein
ET951_RS11715	COG4181	ATPase activity
ET951_RS11720	COG0577	efflux transmembrane transporter activity
ET951_RS11730	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ET951_RS11740	COG1748	Saccharopine dehydrogenase
ET951_RS11755	COG1538	Outer membrane efflux protein
ET951_RS11805	COG0583	DNA-binding transcription factor activity
ET951_RS11815	COG1451	nucleotide metabolic process
ET951_RS11830	COG3063	Type IV pilus biogenesis stability protein PilW
ET951_RS11835	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ET951_RS11855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ET951_RS11870	COG3290	protein histidine kinase activity
ET951_RS11875	COG4565	transcriptional regulatory protein
ET951_RS11885	COG0784	Response regulator, receiver
ET951_RS11885	COG0835	chemotaxis
ET951_RS11920	COG1085	galactose-1-phosphate uridylyltransferase
ET951_RS11925	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ET951_RS11930	COG2017	converts alpha-aldose to the beta-anomer
ET951_RS11940	COG3064	Membrane
ET951_RS11945	COG3059	membrane
ET951_RS11950	COG0753	catalase activity
ET951_RS11965	COG3097	Belongs to the UPF0267 family
ET951_RS11990	COG0316	Belongs to the HesB IscA family
ET951_RS11995	COG0719	Fe-S assembly protein
ET951_RS12000	COG0396	ATPase activity
ET951_RS12005	COG0719	Fe-S assembly protein
ET951_RS12010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ET951_RS12025	COG1780	Probably involved in ribonucleotide reductase function
ET951_RS12030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ET951_RS12040	COG0577	efflux transmembrane transporter activity
ET951_RS12040	COG1136	(ABC) transporter
ET951_RS12050	COG0577	efflux transmembrane transporter activity
ET951_RS12080	COG2723	6-phospho-beta-galactosidase activity
ET951_RS12085	COG1609	Transcriptional regulator
ET951_RS12090	COG0251	oxidation-reduction process
ET951_RS12095	COG2731	YhcH YjgK YiaL family protein
ET951_RS12100	COG0584	glycerophosphoryl diester phosphodiesterase
ET951_RS12105	COG1349	DNA-binding transcription factor activity
ET951_RS12110	COG3842	ATPase activity
ET951_RS12115	COG0395	ABC-type sugar transport system, permease component
ET951_RS12120	COG1175	transmembrane transport
ET951_RS12125	COG1653	transport
ET951_RS12135	COG0811	peptide transport
ET951_RS12140	COG0811	peptide transport
ET951_RS12145	COG0848	biopolymer transport protein
ET951_RS12160	COG1793	dna ligase
ET951_RS12170	COG0534	Mate efflux family protein
ET951_RS12180	COG3001	Fructosamine kinase
ET951_RS12190	COG0791	NLP P60 protein
ET951_RS12205	COG3148	PFAM DTW domain containing protein
ET951_RS12210	COG1940	carbohydrate kinase activity
ET951_RS12225	COG0746	molybdenum cofactor guanylyltransferase activity
ET951_RS12230	COG3842	ATPase activity
ET951_RS12235	COG4662	Binding-protein-dependent transport system inner membrane component
ET951_RS12245	COG2204	response regulator
ET951_RS12250	COG3852	Histidine kinase
ET951_RS12255	COG0488	(ABC) transporter
ET951_RS12265	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ET951_RS12295	COG3383	formate dehydrogenase (NAD+) activity
ET951_RS12295	COG0243	molybdopterin cofactor binding
ET951_RS12300	COG0437	4 iron, 4 sulfur cluster binding
ET951_RS12315	COG0004	ammonium transporteR
ET951_RS12320	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ET951_RS12325	COG1666	GTP binding
ET951_RS12330	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ET951_RS12345	COG2996	Protein conserved in bacteria
ET951_RS12355	COG3008	intermembrane lipid transfer
ET951_RS12360	COG2995	paraquat-inducible protein a
ET951_RS12365	COG1132	(ABC) transporter
ET951_RS12370	COG1956	GAF domain-containing protein
ET951_RS12375	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
ET951_RS12390	COG0308	aminopeptidase N
ET951_RS12405	COG0167	dihydroorotate dehydrogenase activity
ET951_RS12415	COG0116	Belongs to the methyltransferase superfamily
ET951_RS12415	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ET951_RS12425	COG0488	(ABC) transporter
ET951_RS12440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ET951_RS12445	COG1067	ATP-dependent peptidase activity
ET951_RS12450	COG3120	sequence-specific DNA binding
ET951_RS12495	COG4128	Pfam Zonular occludens toxin
ET951_RS12540	COG4128	Pfam Zonular occludens toxin
ET951_RS12630	COG0784	Response regulator, receiver
ET951_RS12630	COG5002	protein histidine kinase activity
ET951_RS12645	COG3278	Belongs to the heme-copper respiratory oxidase family
ET951_RS12660	COG2010	Cytochrome c
ET951_RS12670	COG2217	Heavy metal translocating P-type atpase
ET951_RS12685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ET951_RS12690	COG0589	response to stress
ET951_RS12695	COG0037	tRNA processing
ET951_RS12715	COG3842	ATPase activity
ET951_RS12725	COG1177	transmembrane transport
ET951_RS12755	COG2205	protein histidine kinase activity
ET951_RS12755	COG2202	Pas domain
ET951_RS12760	COG2199	diguanylate cyclase activity
ET951_RS12775	COG1115	amino acid carrier protein
ET951_RS12780	COG1280	lysine exporter protein (LysE YggA)
ET951_RS12800	COG3501	Rhs element vgr protein
ET951_RS12810	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ET951_RS12815	COG1960	acyl-CoA dehydrogenase activity
ET951_RS12825	COG1012	belongs to the aldehyde dehydrogenase family
ET951_RS12830	COG3384	dioxygenase
ET951_RS12845	COG1012	belongs to the aldehyde dehydrogenase family
ET951_RS12865	COG3971	2-oxopent-4-enoate hydratase activity
ET951_RS12885	COG1846	Transcriptional regulator
ET951_RS12925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ET951_RS12945	COG0513	Belongs to the DEAD box helicase family
ET951_RS12965	COG0477	Major facilitator Superfamily
ET951_RS12970	COG0583	DNA-binding transcription factor activity
ET951_RS12975	COG0443	Heat shock 70 kDa protein
ET951_RS12980	COG0402	S-adenosylhomocysteine deaminase activity
ET951_RS12995	COG3766	membrane
ET951_RS13005	COG0754	glutathionylspermidine amidase activity
ET951_RS13015	COG1643	Atp-dependent helicase
ET951_RS13035	COG5001	Diguanylate cyclase
ET951_RS13035	COG3300	MHYT domain
ET951_RS13045	COG0443	Heat shock 70 kDa protein
ET951_RS13050	COG0443	Heat shock 70 kDa protein
ET951_RS13055	COG3706	GGDEF domain
ET951_RS13085	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ET951_RS13090	COG0602	queuosine metabolic process
ET951_RS13095	COG0561	phosphatase activity
ET951_RS13105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET951_RS13110	COG4597	amino acid ABC transporter
ET951_RS13115	COG0765	amino acid transport
ET951_RS13120	COG1126	abc transporter atp-binding protein
ET951_RS13125	COG0670	Belongs to the BI1 family
ET951_RS13130	COG2920	part of a sulfur-relay system
ET951_RS13135	COG1254	Belongs to the acylphosphatase family
ET951_RS13145	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ET951_RS13150	COG3706	GGDEF domain
ET951_RS13165	COG3437	response regulator, receiver
ET951_RS13170	COG0625	glutathione transferase activity
ET951_RS13180	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ET951_RS13190	COG2195	Cleaves the N-terminal amino acid of tripeptides
ET951_RS13220	COG0372	Belongs to the citrate synthase family
ET951_RS13225	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ET951_RS13235	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ET951_RS13265	COG1129	ABC transporter
ET951_RS13290	COG0745	RESPONSE REGULATOR receiver
ET951_RS13295	COG5002	protein histidine kinase activity
ET951_RS13300	COG3713	MltA-interacting MipA family protein
ET951_RS13315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET951_RS13315	COG4191	Histidine kinase
ET951_RS13320	COG0471	metal ion transport
ET951_RS13325	COG0840	transmembrane signaling receptor activity
ET951_RS13330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ET951_RS13350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ET951_RS13360	COG3768	UPF0283 membrane protein
ET951_RS13365	COG3106	COG3106 Predicted ATPase
ET951_RS13385	COG0494	nUDIX hydrolase
ET951_RS13390	COG0814	amino acid
ET951_RS13395	COG1760	l-serine dehydratase
ET951_RS13400	COG0720	synthase
ET951_RS13410	COG0017	Asparaginyl-tRNA synthetase
ET951_RS13415	COG0352	thiamine-phosphate diphosphorylase activity
ET951_RS13415	COG0351	phosphomethylpyrimidine kinase
ET951_RS13420	COG0110	maltose O-acetyltransferase activity
ET951_RS13425	COG2770	Histidine kinase
ET951_RS13425	COG3437	response regulator, receiver
ET951_RS13430	COG1448	Aminotransferase
ET951_RS13445	COG0840	transmembrane signaling receptor activity
ET951_RS13450	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ET951_RS13455	COG2943	transferase activity, transferring hexosyl groups
ET951_RS13460	COG1609	Transcriptional regulator
ET951_RS13465	COG3394	polysaccharide catabolic process
ET951_RS13470	COG1486	melibiose metabolic process
ET951_RS13475	COG1447	Phosphotransferase system cellobiose-specific component IIA
ET951_RS13485	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ET951_RS13490	COG0726	polysaccharide deacetylase
ET951_RS13495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ET951_RS13500	COG1846	Transcriptional regulator
ET951_RS13520	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ET951_RS13535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ET951_RS13540	COG3108	Peptidase M15
ET951_RS13570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ET951_RS13590	COG1054	Belongs to the UPF0176 family
ET951_RS13595	COG1278	Cold shock
ET951_RS13605	COG3088	subunit of a heme lyase
ET951_RS13605	COG4235	cytochrome complex assembly
ET951_RS13615	COG1138	Cytochrome C-type biogenesis protein
ET951_RS13620	COG3301	Polysulphide reductase, NrfD
ET951_RS13625	COG0437	4 iron, 4 sulfur cluster binding
ET951_RS13630	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ET951_RS13635	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ET951_RS13640	COG4235	cytochrome complex assembly
ET951_RS13650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ET951_RS13655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ET951_RS13710	COG4139	cobalamin transport
ET951_RS13715	COG2988	succinylglutamate desuccinylase activity
ET951_RS13730	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ET951_RS13735	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ET951_RS13740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ET951_RS13745	COG1823	symporter activity
ET951_RS13750	COG2925	Exonuclease
ET951_RS13755	COG1380	Effector of murein hydrolase LrgA
ET951_RS13760	COG1346	cytolysis
ET951_RS13780	COG0500	methyltransferase
ET951_RS13790	COG0776	regulation of translation
ET951_RS13795	COG0072	phenylalanine-tRNA ligase activity
ET951_RS13795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ET951_RS13800	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ET951_RS13805	COG0456	acetyltransferase
ET951_RS13810	COG3706	GGDEF domain
ET951_RS13840	COG0322	excinuclease ABC activity
ET951_RS13845	COG2197	response regulator
ET951_RS13850	COG0417	DNA replication proofreading
ET951_RS13855	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ET951_RS13865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ET951_RS13870	COG3099	Belongs to the UPF0263 family
ET951_RS13885	COG1228	amidohydrolase
ET951_RS13890	COG0010	Belongs to the arginase family
ET951_RS13895	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ET951_RS13900	COG2986	histidine ammonia-lyase
ET951_RS13920	COG0277	FAD linked oxidase domain protein
ET951_RS13920	COG0247	lactate metabolic process
ET951_RS13935	COG2885	chlorophyll binding
ET951_RS13955	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ET951_RS13965	COG0281	malic enzyme
ET951_RS13975	COG2949	membrane
ET951_RS13980	COG3706	GGDEF domain
ET951_RS13985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ET951_RS13995	COG0492	ferredoxin-NADP+ reductase activity
ET951_RS14000	COG4988	ABC transporter
ET951_RS14005	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ET951_RS14010	COG1187	pseudouridine synthase activity
ET951_RS14015	COG0009	L-threonylcarbamoyladenylate synthase
ET951_RS14020	COG0613	PHP domain protein
ET951_RS14030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ET951_RS14035	COG0512	Glutamine amidotransferase of anthranilate synthase
ET951_RS14040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ET951_RS14045	COG0135	phosphoribosylanthranilate isomerase activity
ET951_RS14045	COG0134	indole-3-glycerol-phosphate synthase activity
ET951_RS14050	COG0133	tryptophan synthase activity
ET951_RS14055	COG0159	tryptophan synthase activity
ET951_RS14065	COG1435	thymidine kinase activity
ET951_RS14070	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ET951_RS14075	COG1801	Protein of unknown function DUF72
ET951_RS14080	COG4106	trans-aconitate 2-methyltransferase activity
ET951_RS14085	COG0500	methyltransferase
ET951_RS14090	COG0189	ligase activity
ET951_RS14090	COG4067	protein conserved in archaea
ET951_RS14105	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ET951_RS14115	COG3852	Histidine kinase
ET951_RS14130	COG3070	regulator of competence-specific genes
ET951_RS14140	COG2431	L-lysine efflux transmembrane transporter activity
ET951_RS14150	COG0076	glutamate decarboxylase activity
ET951_RS14155	COG1737	Transcriptional regulator
ET951_RS14160	COG1979	alcohol dehydrogenase
ET951_RS14165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ET951_RS14170	COG2985	domain, Protein
ET951_RS14170	COG3273	potassium ion transport
ET951_RS14175	COG0542	response to heat
ET951_RS14180	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ET951_RS14185	COG1278	Cold shock
ET951_RS14195	COG1187	pseudouridine synthase activity
ET951_RS14200	COG0140	phosphoribosyl-ATP diphosphatase activity
ET951_RS14200	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ET951_RS14205	COG0107	imidazoleglycerol-phosphate synthase activity
ET951_RS14210	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ET951_RS14215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ET951_RS14220	COG0131	Imidazoleglycerol-phosphate dehydratase
ET951_RS14220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ET951_RS14225	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ET951_RS14230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ET951_RS14235	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ET951_RS14240	COG1757	Na H antiporter
ET951_RS14245	COG2916	Histone family protein nucleoid-structuring protein H-NS
ET951_RS14250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ET951_RS14255	COG0482	sulfurtransferase activity
ET951_RS14260	COG2915	High frequency lysogenization protein hflD homolog
ET951_RS14265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ET951_RS14270	COG2268	Band 7 protein
ET951_RS14280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ET951_RS14295	COG0300	oxidoreductase activity
ET951_RS14305	COG0501	Belongs to the peptidase M48B family
ET951_RS14315	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ET951_RS14320	COG2226	methyltransferase
ET951_RS14325	COG0156	8-amino-7-oxononanoate synthase activity
ET951_RS14330	COG0527	aspartate kinase activity
ET951_RS14335	COG2239	Acts as a magnesium transporter
ET951_RS14360	COG1166	arginine decarboxylase activity
ET951_RS14380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ET951_RS14385	COG0800	Aldolase
ET951_RS14390	COG1085	galactose-1-phosphate uridylyltransferase
ET951_RS14395	COG1028	Short-chain dehydrogenase reductase Sdr
ET951_RS14415	COG2199	diguanylate cyclase activity
ET951_RS14420	COG3119	arylsulfatase activity
ET951_RS14425	COG3119	arylsulfatase activity
ET951_RS14430	COG0641	radical SAM
ET951_RS14445	COG0601	transmembrane transport
ET951_RS14450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET951_RS14465	COG1414	Transcriptional regulator
ET951_RS14470	COG1686	Belongs to the peptidase S11 family
ET951_RS14485	COG3338	carbonate dehydratase activity
ET951_RS14490	COG2755	lipolytic protein G-D-S-L family
ET951_RS14495	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ET951_RS14495	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ET951_RS14505	COG0509	glycine decarboxylation via glycine cleavage system
ET951_RS14510	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ET951_RS14535	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ET951_RS14540	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ET951_RS14590	COG0653	protein targeting
ET951_RS14635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ET951_RS14645	COG4628	conserved protein (DUF2132)
ET951_RS14665	COG4628	conserved protein (DUF2132)
ET951_RS14705	COG0110	maltose O-acetyltransferase activity
ET951_RS14825	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ET951_RS14850	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ET951_RS14850	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ET951_RS14865	COG1942	4-Oxalocrotonate Tautomerase
ET951_RS15065	COG1280	lysine exporter protein (LysE YggA)
ET951_RS15155	COG4628	conserved protein (DUF2132)
ET951_RS15180	COG2314	TM2 domain
ET951_RS15285	COG0110	maltose O-acetyltransferase activity
ET951_RS15315	COG0653	protein targeting
ET951_RS15335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ET951_RS15405	COG0110	maltose O-acetyltransferase activity
ET951_RS15605	COG1418	mRNA catabolic process
ET951_RS15645	COG4628	conserved protein (DUF2132)
ET951_RS15650	COG1028	Short-chain dehydrogenase reductase Sdr
ET951_RS15660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ET951_RS15725	COG0384	phenazine biosynthesis protein PhzF
ET951_RS15745	COG0384	phenazine biosynthesis protein PhzF
ET951_RS15835	COG4122	O-methyltransferase activity
ET951_RS15845	COG0384	phenazine biosynthesis protein PhzF
ET951_RS15875	COG0456	acetyltransferase
ET951_RS15945	COG2814	Major facilitator Superfamily
ET951_RS15960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ET951_RS15970	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ET951_RS15980	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ET951_RS16005	COG4977	sequence-specific DNA binding
ET951_RS16005	COG1917	Cupin 2, conserved barrel domain protein
ET951_RS16015	COG1328	CTP reductase activity
ET951_RS16020	COG0602	queuosine metabolic process
ET951_RS16030	COG0189	ligase activity
ET951_RS16030	COG4067	protein conserved in archaea
ET951_RS16035	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ET951_RS16040	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ET951_RS16040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ET951_RS16040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ET951_RS16045	COG1105	Belongs to the carbohydrate kinase PfkB family
ET951_RS16050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET951_RS16050	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET951_RS16055	COG1609	Transcriptional regulator
ET951_RS16060	COG0420	3'-5' exonuclease activity
ET951_RS16065	COG0419	ATPase involved in DNA repair
ET951_RS16070	COG0784	Response regulator, receiver
ET951_RS16070	COG2205	protein histidine kinase activity
ET951_RS16075	COG0156	8-amino-7-oxononanoate synthase activity
ET951_RS16085	COG0038	chloride channel
ET951_RS16090	COG0523	cobalamin synthesis protein
ET951_RS16100	COG4409	exo-alpha-(2->6)-sialidase activity
ET951_RS16105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ET951_RS16110	COG1940	carbohydrate kinase activity
ET951_RS16125	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ET951_RS16130	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ET951_RS16140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ET951_RS16145	COG1737	Transcriptional regulator
ET951_RS16150	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ET951_RS16155	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ET951_RS16180	COG5001	Diguanylate cyclase
ET951_RS16180	COG3300	MHYT domain
ET951_RS16190	COG3038	cytochrome b561
ET951_RS16205	COG0583	DNA-binding transcription factor activity
ET951_RS16215	COG3593	DNA synthesis involved in DNA repair
ET951_RS16220	COG0737	Belongs to the 5'-nucleotidase family
ET951_RS16235	COG2824	Alkylphosphonate utilization operon protein PhnA
ET951_RS16270	COG5002	protein histidine kinase activity
ET951_RS16270	COG5001	Diguanylate cyclase
ET951_RS16280	COG1309	transcriptional regulator
ET951_RS16315	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ET951_RS16320	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ET951_RS16345	COG3140	Belongs to the UPF0181 family
ET951_RS16430	COG4771	TonB-dependent receptor
ET951_RS16435	COG2814	Major facilitator Superfamily
ET951_RS16440	COG3433	isochorismatase activity
ET951_RS16440	COG2226	methyltransferase
ET951_RS16440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ET951_RS16465	COG1021	2,3-dihydroxybenzoate-AMP ligase
ET951_RS16470	COG1132	(ABC) transporter
ET951_RS16475	COG1132	(ABC) transporter
ET951_RS16485	COG0023	Translation Initiation Factor
ET951_RS16505	COG0045	succinate-CoA ligase (ADP-forming) activity
ET951_RS16505	COG1042	CoA-binding domain protein
ET951_RS16505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ET951_RS16510	COG0583	DNA-binding transcription factor activity
ET951_RS16515	COG4771	TonB-dependent receptor
ET951_RS16530	COG2050	protein possibly involved in aromatic compounds catabolism
ET951_RS16550	COG0625	glutathione transferase activity
ET951_RS16575	COG4172	Belongs to the ABC transporter superfamily
ET951_RS16580	COG4239	(ABC) transporter, permease
ET951_RS16585	COG4174	ABC transporter (Permease)
ET951_RS16590	COG4166	transmembrane transport
ET951_RS16615	COG3104	oligopeptide transport
ET951_RS16635	COG3842	ATPase activity
ET951_RS16640	COG1840	ABC-type Fe3 transport system, periplasmic component
ET951_RS16645	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ET951_RS16650	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ET951_RS16655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ET951_RS16660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ET951_RS16665	COG1011	Hydrolase
ET951_RS16675	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ET951_RS16680	COG1454	alcohol dehydrogenase
ET951_RS16685	COG1970	mechanosensitive ion channel activity
ET951_RS16690	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ET951_RS16695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ET951_RS16695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ET951_RS16700	COG0302	gtp cyclohydrolase
ET951_RS16710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ET951_RS16720	COG2897	thiosulfate sulfurtransferase activity
ET951_RS16730	COG2390	Transcriptional regulator
ET951_RS16735	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ET951_RS16740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ET951_RS16765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ET951_RS16800	COG0583	DNA-binding transcription factor activity
ET951_RS16855	COG1566	PFAM secretion protein HlyD family protein
ET951_RS16940	COG1999	signal sequence binding
ET951_RS16945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ET951_RS16955	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ET951_RS16970	COG0545	Peptidyl-prolyl cis-trans isomerase
ET951_RS16980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ET951_RS16985	COG0840	transmembrane signaling receptor activity
ET951_RS16990	COG3069	C4-dicarboxylate transmembrane transporter activity
ET951_RS16995	COG1760	l-serine dehydratase
ET951_RS17000	COG2197	response regulator
ET951_RS17005	COG3850	Histidine kinase
ET951_RS17010	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ET951_RS17020	COG0243	molybdopterin cofactor binding
ET951_RS17030	COG3005	denitrification pathway
ET951_RS17040	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ET951_RS17045	COG2197	response regulator
ET951_RS17050	COG3851	Histidine kinase
ET951_RS17055	COG2271	Major facilitator Superfamily
ET951_RS17060	COG1840	ABC-type Fe3 transport system, periplasmic component
ET951_RS17070	COG3842	ATPase activity
ET951_RS17125	COG4964	Belongs to the GSP D family
ET951_RS17145	COG0583	DNA-binding transcription factor activity
ET951_RS17155	COG3243	poly(R)-hydroxyalkanoic acid synthase
ET951_RS17165	COG0183	Belongs to the thiolase family
ET951_RS17185	COG1447	Phosphotransferase system cellobiose-specific component IIA
ET951_RS17190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ET951_RS17200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ET951_RS17205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ET951_RS17225	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ET951_RS17235	COG1979	alcohol dehydrogenase
ET951_RS17250	COG4191	Histidine kinase
ET951_RS17260	COG2271	Major facilitator Superfamily
ET951_RS17265	COG0469	pyruvate kinase activity
ET951_RS17270	COG2205	protein histidine kinase activity
ET951_RS17270	COG2198	Histidine kinase
ET951_RS17270	COG0784	Response regulator, receiver
ET951_RS17275	COG1879	ABC-type sugar transport system periplasmic component
ET951_RS17280	COG1803	Methylglyoxal synthase
ET951_RS17285	COG1335	isochorismatase
ET951_RS17295	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ET951_RS17315	COG0210	DNA helicase
ET951_RS17320	COG1289	transmembrane transporter activity
ET951_RS17340	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ET951_RS17345	COG4149	molybdate abc transporter
ET951_RS17350	COG0725	ABC transporter, periplasmic molybdate-binding protein
ET951_RS17355	COG1492	cobalamin metabolic process
ET951_RS17375	COG0784	Response regulator, receiver
ET951_RS17375	COG5002	protein histidine kinase activity
ET951_RS17380	COG1879	ABC-type sugar transport system periplasmic component
ET951_RS17390	COG2827	Endonuclease containing a URI domain
ET951_RS17395	COG3132	Protein of unknown function, DUF480
ET951_RS17405	COG2926	Belongs to the UPF0265 family
ET951_RS17415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ET951_RS17420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ET951_RS17425	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ET951_RS17430	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
ET951_RS17435	COG0247	lactate metabolic process
ET951_RS17445	COG1215	transferase activity, transferring glycosyl groups
ET951_RS17455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ET951_RS17460	COG3118	belongs to the thioredoxin family
ET951_RS17490	COG0243	molybdopterin cofactor binding
ET951_RS17495	COG0583	DNA-binding transcription factor activity
ET951_RS17500	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ET951_RS17505	COG4160	amino acid transport
ET951_RS17510	COG4215	(ABC) transporter
ET951_RS17515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET951_RS17520	COG1126	abc transporter atp-binding protein
ET951_RS17530	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ET951_RS17540	COG0494	nUDIX hydrolase
ET951_RS17545	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ET951_RS17560	COG0513	Belongs to the DEAD box helicase family
ET951_RS17565	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
ET951_RS17575	COG0814	amino acid
ET951_RS17580	COG0840	transmembrane signaling receptor activity
ET951_RS17585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ET951_RS17590	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ET951_RS17595	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ET951_RS17600	COG1984	allophanate hydrolase subunit 2
ET951_RS17615	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ET951_RS17620	COG4181	ATPase activity
ET951_RS17630	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ET951_RS17635	COG1716	ATPase activity
ET951_RS17635	COG5001	Diguanylate cyclase
ET951_RS17645	COG0484	heat shock protein binding
ET951_RS17680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ET951_RS17685	COG1368	sulfuric ester hydrolase activity
ET951_RS17695	COG0513	Belongs to the DEAD box helicase family
ET951_RS17710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ET951_RS17720	COG3046	protein related to deoxyribodipyrimidine photolyase
ET951_RS17725	COG3397	chitin binding
ET951_RS17730	COG3344	reverse transcriptase
ET951_RS17760	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ET951_RS17775	COG1172	Belongs to the binding-protein-dependent transport system permease family
ET951_RS17780	COG1129	ABC transporter
ET951_RS17785	COG1454	alcohol dehydrogenase
ET951_RS17790	COG0235	Class ii aldolase
ET951_RS17795	COG4154	Belongs to the RbsD FucU family
ET951_RS17800	COG1070	Carbohydrate kinase
ET951_RS17805	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
ET951_RS17810	COG1349	DNA-binding transcription factor activity
ET951_RS17840	COG0561	phosphatase activity
ET951_RS17845	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ET951_RS17850	COG3623	hexulose-6-phosphate isomerase
ET951_RS17865	COG2149	membrane
ET951_RS17875	COG1263	PTS System
ET951_RS17875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET951_RS17880	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ET951_RS17900	COG1073	alpha beta
ET951_RS17905	COG1073	alpha beta
ET951_RS17915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ET951_RS17935	COG4604	ABC transporter, ATP-binding protein
ET951_RS17940	COG4605	iron ion homeostasis
ET951_RS17945	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET951_RS17970	COG0840	transmembrane signaling receptor activity
ET951_RS17980	COG3240	lipase activity
ET951_RS17985	COG3706	GGDEF domain
ET951_RS17995	COG2814	Major facilitator Superfamily
ET951_RS18000	COG1757	Na H antiporter
ET951_RS18010	COG4191	Histidine kinase
ET951_RS18010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET951_RS18015	COG0784	Response regulator, receiver
ET951_RS18015	COG3437	response regulator, receiver
ET951_RS18020	COG0840	transmembrane signaling receptor activity
ET951_RS18030	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ET951_RS18035	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ET951_RS18040	COG0513	Belongs to the DEAD box helicase family
ET951_RS18050	COG4821	SIS domain
ET951_RS18055	COG4821	SIS domain
ET951_RS18065	COG3715	PTS system
ET951_RS18070	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET951_RS18090	COG3119	arylsulfatase activity
ET951_RS18095	COG0641	radical SAM
ET951_RS18105	COG2207	Transcriptional regulator
ET951_RS18105	COG1917	Cupin 2, conserved barrel domain protein
ET951_RS18125	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ET951_RS18130	COG2188	Transcriptional regulator
ET951_RS18135	COG4821	SIS domain
ET951_RS18165	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ET951_RS18175	COG0516	GMP reductase activity
ET951_RS18185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ET951_RS18195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ET951_RS18200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ET951_RS18200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ET951_RS18225	COG3036	rescue of stalled ribosome
ET951_RS18230	COG1278	Cold shock
ET951_RS18240	COG3604	Transcriptional regulator
ET951_RS18250	COG2195	Cleaves the N-terminal amino acid of tripeptides
ET951_RS18255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ET951_RS18270	COG0840	transmembrane signaling receptor activity
ET951_RS18275	COG0714	Associated with various cellular activities
ET951_RS18295	COG2304	oxidoreductase activity
ET951_RS18310	COG1278	Cold shock
ET951_RS18315	COG5002	protein histidine kinase activity
ET951_RS18315	COG5001	Diguanylate cyclase
ET951_RS18325	COG3530	Putative quorum-sensing-regulated virulence factor
ET951_RS18340	COG0814	amino acid
ET951_RS18345	COG0488	(ABC) transporter
ET951_RS18355	COG1609	Transcriptional regulator
ET951_RS18360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET951_RS18375	COG0242	peptide deformylase activity
ET951_RS18385	COG0579	oxidoreductase
ET951_RS18405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ET951_RS18430	COG2271	Major facilitator Superfamily
ET951_RS18435	COG0584	glycerophosphoryl diester phosphodiesterase
ET951_RS18445	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ET951_RS18455	COG1609	Transcriptional regulator
ET951_RS18460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ET951_RS18465	COG1879	ABC-type sugar transport system periplasmic component
ET951_RS18470	COG1172	Belongs to the binding-protein-dependent transport system permease family
ET951_RS18475	COG1129	ABC transporter
ET951_RS18480	COG1869	D-ribose catabolic process
ET951_RS18525	COG3829	transcription factor binding
ET951_RS18590	COG0564	pseudouridine synthase activity
ET951_RS18600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ET951_RS18605	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ET951_RS18615	COG0673	inositol 2-dehydrogenase activity
ET951_RS18620	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ET951_RS18650	COG1342	Belongs to the UPF0251 family
ET951_RS18665	COG1301	dicarboxylic acid transport
ET951_RS18670	COG0700	Nucleoside recognition
ET951_RS18675	COG3366	ferrous iron transmembrane transporter activity
ET951_RS18680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ET951_RS18685	COG4565	transcriptional regulatory protein
ET951_RS18695	COG0471	metal ion transport
ET951_RS18705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ET951_RS18710	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ET951_RS18715	COG2259	Doxx family
ET951_RS18740	COG0363	glucosamine-6-phosphate deaminase activity
ET951_RS18755	COG4580	involved in the transport of maltose and maltodextrins
ET951_RS18765	COG1914	H( )-stimulated, divalent metal cation uptake system
ET951_RS18775	COG0840	transmembrane signaling receptor activity
ET951_RS18785	COG0840	transmembrane signaling receptor activity
ET951_RS18800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ET951_RS18830	COG1280	lysine exporter protein (LysE YggA)
ET951_RS18860	COG0513	Belongs to the DEAD box helicase family
ET951_RS18870	COG2186	Transcriptional regulator
ET951_RS18880	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ET951_RS18890	COG0246	Mannitol dehydrogenase
ET951_RS18895	COG1904	glucuronate isomerase
ET951_RS18900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ET951_RS18905	COG0800	Aldolase
ET951_RS18915	COG0583	DNA-binding transcription factor activity
ET951_RS18925	COG1902	pentaerythritol trinitrate reductase activity
ET951_RS18930	COG2964	Protein conserved in bacteria
ET951_RS18940	COG0251	oxidation-reduction process
ET951_RS18945	COG0814	amino acid
ET951_RS18955	COG1132	(ABC) transporter
ET951_RS18965	COG1280	lysine exporter protein (LysE YggA)
ET951_RS18970	COG2207	Transcriptional regulator
ET951_RS18990	COG1846	Transcriptional regulator
ET951_RS18995	COG1764	response to oxidative stress
ET951_RS19000	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ET951_RS19005	COG0697	spore germination
ET951_RS19010	COG0678	peroxiredoxin activity
ET951_RS19010	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ET951_RS19025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ET951_RS19030	COG0583	DNA-binding transcription factor activity
ET951_RS19035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ET951_RS19040	COG0569	domain protein
ET951_RS19045	COG0745	RESPONSE REGULATOR receiver
ET951_RS19050	COG2205	protein histidine kinase activity
ET951_RS19065	COG2814	Major facilitator Superfamily
ET951_RS19070	COG0583	DNA-binding transcription factor activity
ET951_RS19080	COG0739	heme binding
ET951_RS19090	COG0659	secondary active sulfate transmembrane transporter activity
ET951_RS19095	COG3314	Sporulation integral membrane protein YlbJ
ET951_RS19110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ET951_RS19115	COG0581	inorganic phosphate transmembrane transporter activity
ET951_RS19120	COG0573	inorganic phosphate transmembrane transporter activity
ET951_RS19125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ET951_RS19130	COG0840	transmembrane signaling receptor activity
ET951_RS19140	COG0513	Belongs to the DEAD box helicase family
ET951_RS19150	COG1388	LysM domain
ET951_RS19150	COG1376	ErfK ybiS ycfS ynhG family protein
ET951_RS19155	COG0415	Belongs to the DNA photolyase family
ET951_RS19160	COG0789	Transcriptional regulator
ET951_RS19165	COG3272	Protein of unknown function (DUF1722)
ET951_RS19170	COG0813	purine-nucleoside phosphorylase activity
ET951_RS19195	COG1566	PFAM secretion protein HlyD family protein
ET951_RS19210	COG3655	Transcriptional regulator
ET951_RS19225	COG0786	glutamate:sodium symporter activity
ET951_RS19240	COG1999	signal sequence binding
ET951_RS19245	COG2847	Copper chaperone PCu(A)C
ET951_RS19250	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ET951_RS19260	COG0671	phosphoesterase, PA-phosphatase related
ET951_RS19290	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ET951_RS19295	COG0471	metal ion transport
ET951_RS19330	COG3501	Rhs element vgr protein
ET951_RS19340	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ET951_RS19345	COG1640	4-alpha-glucanotransferase
ET951_RS19350	COG0058	SHG alpha-glucan phosphorylase activity
ET951_RS19355	COG2909	trisaccharide binding
ET951_RS19360	COG3344	reverse transcriptase
ET951_RS19375	COG2084	Dehydrogenase
ET951_RS19380	COG0217	transcriptional regulatory protein
ET951_RS19415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ET951_RS19420	COG1444	tRNA N-acetyltransferase activity
ET951_RS19430	COG1022	Amp-dependent synthetase and ligase
ET951_RS19440	COG1028	Short-chain dehydrogenase reductase Sdr
ET951_RS19460	COG2194	sulfuric ester hydrolase activity
ET951_RS19470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET951_RS19475	COG0601	transmembrane transport
ET951_RS19480	COG0747	negative chemotaxis
ET951_RS19490	COG0745	RESPONSE REGULATOR receiver
ET951_RS19495	COG2198	Histidine kinase
ET951_RS19495	COG0643	Histidine kinase
ET951_RS19500	COG0835	chemotaxis
ET951_RS19505	COG0835	chemotaxis
ET951_RS19510	COG0840	transmembrane signaling receptor activity
ET951_RS19515	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ET951_RS19580	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ET951_RS19605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ET951_RS19655	COG2197	response regulator
ET951_RS19665	COG1982	Orn Lys Arg decarboxylase major
ET951_RS19670	COG0531	amino acid
ET951_RS19685	COG1901	pseudouridine methyltransferase
ET951_RS19700	COG4221	oxidoreductase activity
ET951_RS19715	COG2910	NAD(P)H-binding
ET951_RS19735	COG0655	NAD(P)H dehydrogenase (quinone) activity
ET951_RS19740	COG0583	DNA-binding transcription factor activity
ET951_RS19755	COG0697	spore germination
ET951_RS19785	COG0673	inositol 2-dehydrogenase activity
ET951_RS19790	COG3722	fumarate hydratase activity
ET951_RS19795	COG0246	Mannitol dehydrogenase
ET951_RS19800	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET951_RS19800	COG2213	PTS system mannitol-specific
ET951_RS19805	COG0739	heme binding
ET951_RS19815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ET951_RS19820	COG4597	amino acid ABC transporter
ET951_RS19825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET951_RS19835	COG1126	abc transporter atp-binding protein
ET951_RS19840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ET951_RS19845	COG0534	Mate efflux family protein
ET951_RS19855	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ET951_RS19860	COG1366	Belongs to the anti-sigma-factor antagonist family
ET951_RS19870	COG2172	sigma factor antagonist activity
ET951_RS19880	COG0784	Response regulator, receiver
ET951_RS19880	COG2205	protein histidine kinase activity
ET951_RS19880	COG5002	protein histidine kinase activity
ET951_RS19885	COG3437	response regulator, receiver
ET951_RS19895	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ET951_RS19910	COG1620	l-lactate permease
ET951_RS19915	COG0583	DNA-binding transcription factor activity
ET951_RS19920	COG4172	Belongs to the ABC transporter superfamily
ET951_RS19930	COG1067	ATP-dependent peptidase activity
ET951_RS19940	COG2211	Major facilitator Superfamily
ET951_RS19950	COG3123	guanosine phosphorylase activity
ET951_RS19955	COG1741	Belongs to the pirin family
ET951_RS19965	COG5001	Diguanylate cyclase
ET951_RS19970	COG0583	DNA-binding transcription factor activity
ET951_RS20005	COG3706	GGDEF domain
ET951_RS20010	COG1846	Transcriptional regulator
ET951_RS20015	COG0835	chemotaxis
ET951_RS20015	COG0784	Response regulator, receiver
ET951_RS20020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ET951_RS20035	COG0583	DNA-binding transcription factor activity
ET951_RS20045	COG2197	response regulator
ET951_RS20050	COG0393	Putative heavy-metal-binding
ET951_RS20060	COG0741	lytic transglycosylase activity
ET951_RS20060	COG1388	LysM domain
ET951_RS20080	COG1815	bacterial-type flagellum-dependent cell motility
ET951_RS20085	COG1558	bacterial-type flagellum-dependent cell motility
ET951_RS20090	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ET951_RS20095	COG1749	Flagellar hook protein flgE
ET951_RS20100	COG4787	bacterial-type flagellum-dependent cell motility
ET951_RS20105	COG4786	Flagellar basal body rod
ET951_RS20110	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ET951_RS20115	COG1706	bacterial-type flagellum-dependent cell motility
ET951_RS20125	COG1256	bacterial-type flagellum assembly
ET951_RS20125	COG4786	Flagellar basal body rod
ET951_RS20140	COG1360	Flagellar Motor Protein
ET951_RS20145	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ET951_RS20150	COG1191	sigma factor activity
ET951_RS20155	COG1580	Controls the rotational direction of flagella during chemotaxis
ET951_RS20175	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ET951_RS20180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ET951_RS20200	COG1987	bacterial-type flagellum assembly
ET951_RS20230	COG1677	Flagellar hook-basal body complex protein FliE
ET951_RS20240	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ET951_RS20270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ET951_RS20270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET951_RS20270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ET951_RS20275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ET951_RS20275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET951_RS20275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ET951_RS20285	COG1349	DNA-binding transcription factor activity
ET951_RS20305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ET951_RS20310	COG3842	ATPase activity
ET951_RS20320	COG1175	transmembrane transport
ET951_RS20325	COG3833	ABC-type maltose transport systems, permease component
ET951_RS20340	COG0737	Belongs to the 5'-nucleotidase family
ET951_RS20350	COG1349	DNA-binding transcription factor activity
ET951_RS20355	COG2199	diguanylate cyclase activity
ET951_RS20380	COG1278	Cold shock
ET951_RS20385	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ET951_RS20395	COG0488	(ABC) transporter
ET951_RS20400	COG2354	Protein conserved in bacteria
ET951_RS20405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ET951_RS20425	COG0418	dihydroorotase activity
ET951_RS20430	COG0633	Ferredoxin
ET951_RS20430	COG3217	Mosc domain protein beta barrel domain protein
ET951_RS20430	COG0633	Ferredoxin
ET951_RS20430	COG3217	Mosc domain protein beta barrel domain protein
ET951_RS20470	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ET951_RS20475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET951_RS20485	COG0848	biopolymer transport protein
ET951_RS20490	COG0811	peptide transport
ET951_RS20495	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ET951_RS20505	COG3721	Heme iron utilization protein
ET951_RS20510	COG0748	coenzyme F420 binding
ET951_RS20520	COG1858	cytochrome C peroxidase
ET951_RS20525	COG3835	regulator
ET951_RS20530	COG2610	gluconate transmembrane transporter activity
ET951_RS20535	COG1929	Belongs to the glycerate kinase type-1 family
ET951_RS20555	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ET951_RS20560	COG0363	glucosamine-6-phosphate deaminase activity
ET951_RS20565	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ET951_RS20570	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ET951_RS20585	COG3706	GGDEF domain
ET951_RS20585	COG5001	Diguanylate cyclase
ET951_RS20585	COG2203	Gaf domain
ET951_RS20585	COG4251	negative regulation of phosphorylation
ET951_RS20600	COG0346	lactoylglutathione lyase activity
ET951_RS20610	COG2873	o-acetylhomoserine
ET951_RS20615	COG0156	8-amino-7-oxononanoate synthase activity
ET951_RS20620	COG1063	alcohol dehydrogenase
ET951_RS20635	COG2814	Major facilitator Superfamily
ET951_RS20650	COG1686	Belongs to the peptidase S11 family
ET951_RS20660	COG3047	cAMP biosynthetic process
ET951_RS20665	COG3227	Zinc metalloprotease (Elastase)
ET951_RS20680	COG2267	carboxylic ester hydrolase activity
ET951_RS20685	COG2067	long-chain fatty acid transport protein
ET951_RS20690	COG0366	Alpha amylase catalytic
ET951_RS20695	COG4989	oxidoreductase activity
ET951_RS20705	COG1136	(ABC) transporter
ET951_RS20710	COG1136	(ABC) transporter
ET951_RS20710	COG0577	efflux transmembrane transporter activity
ET951_RS20725	COG3275	phosphorelay sensor kinase activity
ET951_RS20730	COG3279	Response regulator of the LytR AlgR family
ET951_RS20745	COG0531	amino acid
ET951_RS20765	COG5001	Diguanylate cyclase
ET951_RS20765	COG3300	MHYT domain
ET951_RS20775	COG1765	OsmC-like protein
ET951_RS20780	COG1253	flavin adenine dinucleotide binding
ET951_RS20795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ET951_RS20810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ET951_RS20815	COG3186	Phenylalanine-4-hydroxylase
ET951_RS20820	COG2154	pterin-4-alpha-carbinolamine dehydratase
ET951_RS20830	COG0534	Mate efflux family protein
ET951_RS20845	COG0456	acetyltransferase
ET951_RS20850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ET951_RS20855	COG0662	Cupin 2, conserved barrel domain protein