locus-tag	class	description
AL543_RS00020	COG2814	Major facilitator Superfamily
AL543_RS00035	COG3335	DDE superfamily endonuclease
AL543_RS00055	COG3335	DDE superfamily endonuclease
AL543_RS00075	COG3157	Type VI secretion system effector, Hcp
AL543_RS00085	COG1349	DNA-binding transcription factor activity
AL543_RS00090	COG2084	Dehydrogenase
AL543_RS00095	COG3395	kinase activity
AL543_RS00100	COG0235	Class ii aldolase
AL543_RS00105	COG3622	Belongs to the hyi family
AL543_RS00110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL543_RS00115	COG2610	gluconate transmembrane transporter activity
AL543_RS00220	COG0270	DNA (cytosine-5-)-methyltransferase activity
AL543_RS00265	COG4626	Terminase
AL543_RS00265	COG1802	Transcriptional regulator
AL543_RS00310	COG1063	alcohol dehydrogenase
AL543_RS00320	COG2873	o-acetylhomoserine
AL543_RS00330	COG0346	lactoylglutathione lyase activity
AL543_RS00345	COG4251	negative regulation of phosphorylation
AL543_RS00345	COG2203	Gaf domain
AL543_RS00345	COG5001	Diguanylate cyclase
AL543_RS00345	COG3706	GGDEF domain
AL543_RS00360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AL543_RS00365	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL543_RS00370	COG0363	glucosamine-6-phosphate deaminase activity
AL543_RS00375	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL543_RS00395	COG1929	Belongs to the glycerate kinase type-1 family
AL543_RS00400	COG2610	gluconate transmembrane transporter activity
AL543_RS00405	COG3835	regulator
AL543_RS00410	COG1858	cytochrome C peroxidase
AL543_RS00420	COG0748	coenzyme F420 binding
AL543_RS00425	COG3721	Heme iron utilization protein
AL543_RS00435	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL543_RS00440	COG0811	peptide transport
AL543_RS00445	COG0848	biopolymer transport protein
AL543_RS00450	COG4558	Periplasmic binding protein
AL543_RS00455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL543_RS00460	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL543_RS00480	COG3335	DDE superfamily endonuclease
AL543_RS00505	COG3217	Mosc domain protein beta barrel domain protein
AL543_RS00505	COG3217	Mosc domain protein beta barrel domain protein
AL543_RS00505	COG0633	Ferredoxin
AL543_RS00505	COG0633	Ferredoxin
AL543_RS00510	COG0418	dihydroorotase activity
AL543_RS00520	COG3335	DDE superfamily endonuclease
AL543_RS00530	COG3152	Membrane
AL543_RS00540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL543_RS00545	COG2354	Protein conserved in bacteria
AL543_RS00550	COG0488	(ABC) transporter
AL543_RS00560	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL543_RS00565	COG1278	Cold shock
AL543_RS00590	COG2199	diguanylate cyclase activity
AL543_RS00595	COG1349	DNA-binding transcription factor activity
AL543_RS00605	COG0737	Belongs to the 5'-nucleotidase family
AL543_RS00620	COG3833	ABC-type maltose transport systems, permease component
AL543_RS00625	COG1175	transmembrane transport
AL543_RS00635	COG3842	ATPase activity
AL543_RS00640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL543_RS00655	COG0393	Putative heavy-metal-binding
AL543_RS00660	COG2197	response regulator
AL543_RS00680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL543_RS00685	COG0835	chemotaxis
AL543_RS00685	COG0784	Response regulator, receiver
AL543_RS00690	COG1846	Transcriptional regulator
AL543_RS00695	COG3706	GGDEF domain
AL543_RS00730	COG0583	DNA-binding transcription factor activity
AL543_RS00735	COG5001	Diguanylate cyclase
AL543_RS00745	COG1741	Belongs to the pirin family
AL543_RS00750	COG3123	guanosine phosphorylase activity
AL543_RS00760	COG2211	Major facilitator Superfamily
AL543_RS00775	COG1067	ATP-dependent peptidase activity
AL543_RS00785	COG4172	Belongs to the ABC transporter superfamily
AL543_RS00790	COG0583	DNA-binding transcription factor activity
AL543_RS00795	COG1620	l-lactate permease
AL543_RS00810	COG3385	transposase activity
AL543_RS00815	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL543_RS00830	COG2172	sigma factor antagonist activity
AL543_RS00840	COG1366	Belongs to the anti-sigma-factor antagonist family
AL543_RS00845	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AL543_RS00850	COG0840	transmembrane signaling receptor activity
AL543_RS00855	COG0534	Mate efflux family protein
AL543_RS00865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL543_RS00870	COG1126	abc transporter atp-binding protein
AL543_RS00880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL543_RS00885	COG4215	(ABC) transporter
AL543_RS00890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL543_RS00900	COG0739	heme binding
AL543_RS00905	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL543_RS00905	COG2213	PTS system mannitol-specific
AL543_RS00910	COG0246	Mannitol dehydrogenase
AL543_RS00915	COG3722	fumarate hydratase activity
AL543_RS00920	COG0673	inositol 2-dehydrogenase activity
AL543_RS00950	COG0697	spore germination
AL543_RS00965	COG0583	DNA-binding transcription factor activity
AL543_RS00970	COG0655	NAD(P)H dehydrogenase (quinone) activity
AL543_RS00985	COG0697	spore germination
AL543_RS00990	COG2910	NAD(P)H-binding
AL543_RS01005	COG3335	DDE superfamily endonuclease
AL543_RS01010	COG4221	oxidoreductase activity
AL543_RS01025	COG1901	pseudouridine methyltransferase
AL543_RS01040	COG0531	amino acid
AL543_RS01045	COG1982	Orn Lys Arg decarboxylase major
AL543_RS01055	COG2197	response regulator
AL543_RS01095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL543_RS01120	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL543_RS01160	COG3537	Alpha-1,2-mannosidase
AL543_RS01200	COG0840	transmembrane signaling receptor activity
AL543_RS01205	COG0835	chemotaxis
AL543_RS01210	COG0835	chemotaxis
AL543_RS01215	COG0643	Histidine kinase
AL543_RS01215	COG2198	Histidine kinase
AL543_RS01230	COG0747	negative chemotaxis
AL543_RS01235	COG0601	transmembrane transport
AL543_RS01240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL543_RS01250	COG2194	sulfuric ester hydrolase activity
AL543_RS01260	COG0642	Histidine kinase
AL543_RS01275	COG1028	Short-chain dehydrogenase reductase Sdr
AL543_RS01295	COG1444	tRNA N-acetyltransferase activity
AL543_RS01300	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL543_RS01340	COG0217	transcriptional regulatory protein
AL543_RS01345	COG2084	Dehydrogenase
AL543_RS01360	COG2909	trisaccharide binding
AL543_RS01365	COG0058	SHG alpha-glucan phosphorylase activity
AL543_RS01370	COG1640	4-alpha-glucanotransferase
AL543_RS01375	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL543_RS01385	COG3501	Rhs element vgr protein
AL543_RS01420	COG0471	metal ion transport
AL543_RS01425	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL543_RS01455	COG0671	phosphoesterase, PA-phosphatase related
AL543_RS01465	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AL543_RS01470	COG2847	Copper chaperone PCu(A)C
AL543_RS01475	COG1999	signal sequence binding
AL543_RS01490	COG0786	glutamate:sodium symporter activity
AL543_RS01505	COG3655	Transcriptional regulator
AL543_RS01520	COG1566	PFAM secretion protein HlyD family protein
AL543_RS01545	COG0813	purine-nucleoside phosphorylase activity
AL543_RS01555	COG3272	Protein of unknown function (DUF1722)
AL543_RS01560	COG0789	Transcriptional regulator
AL543_RS01565	COG0415	Belongs to the DNA photolyase family
AL543_RS01570	COG1376	ErfK ybiS ycfS ynhG family protein
AL543_RS01570	COG1388	LysM domain
AL543_RS01580	COG0513	Belongs to the DEAD box helicase family
AL543_RS01590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL543_RS01595	COG0573	inorganic phosphate transmembrane transporter activity
AL543_RS01600	COG0581	inorganic phosphate transmembrane transporter activity
AL543_RS01605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL543_RS01620	COG3314	Sporulation integral membrane protein YlbJ
AL543_RS01625	COG0659	secondary active sulfate transmembrane transporter activity
AL543_RS01635	COG0739	heme binding
AL543_RS01645	COG0583	DNA-binding transcription factor activity
AL543_RS01650	COG2814	Major facilitator Superfamily
AL543_RS01660	COG3335	DDE superfamily endonuclease
AL543_RS01670	COG2205	protein histidine kinase activity
AL543_RS01675	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL543_RS01690	COG0678	peroxiredoxin activity
AL543_RS01690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL543_RS01695	COG0697	spore germination
AL543_RS01700	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL543_RS01705	COG1764	response to oxidative stress
AL543_RS01710	COG1846	Transcriptional regulator
AL543_RS01730	COG2207	Transcriptional regulator
AL543_RS01735	COG1280	lysine exporter protein (LysE YggA)
AL543_RS01745	COG1132	(ABC) transporter
AL543_RS01755	COG1902	pentaerythritol trinitrate reductase activity
AL543_RS01765	COG0583	DNA-binding transcription factor activity
AL543_RS01775	COG0800	Aldolase
AL543_RS01780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL543_RS01785	COG1904	glucuronate isomerase
AL543_RS01790	COG0246	Mannitol dehydrogenase
AL543_RS01800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL543_RS01810	COG2186	Transcriptional regulator
AL543_RS01820	COG0513	Belongs to the DEAD box helicase family
AL543_RS01840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL543_RS01855	COG0840	transmembrane signaling receptor activity
AL543_RS01870	COG0840	transmembrane signaling receptor activity
AL543_RS01880	COG1914	H( )-stimulated, divalent metal cation uptake system
AL543_RS01890	COG4580	involved in the transport of maltose and maltodextrins
AL543_RS01905	COG0363	glucosamine-6-phosphate deaminase activity
AL543_RS01930	COG2259	Doxx family
AL543_RS01935	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL543_RS01940	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL543_RS01950	COG0471	metal ion transport
AL543_RS01960	COG4565	transcriptional regulatory protein
AL543_RS01965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AL543_RS01970	COG3366	ferrous iron transmembrane transporter activity
AL543_RS01975	COG0700	Nucleoside recognition
AL543_RS01980	COG1301	dicarboxylic acid transport
AL543_RS01995	COG1342	Belongs to the UPF0251 family
AL543_RS02025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL543_RS02030	COG0673	inositol 2-dehydrogenase activity
AL543_RS02040	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL543_RS02045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL543_RS02060	COG0564	pseudouridine synthase activity
AL543_RS02125	COG3829	transcription factor binding
AL543_RS02150	COG3409	Peptidoglycan-binding domain 1 protein
AL543_RS02150	COG3501	Rhs element vgr protein
AL543_RS02160	COG3335	DDE superfamily endonuclease
AL543_RS02180	COG1869	D-ribose catabolic process
AL543_RS02185	COG1129	ABC transporter
AL543_RS02190	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL543_RS02195	COG1879	ABC-type sugar transport system periplasmic component
AL543_RS02200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL543_RS02205	COG1609	Transcriptional regulator
AL543_RS02215	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AL543_RS02225	COG0584	glycerophosphoryl diester phosphodiesterase
AL543_RS02230	COG2271	Major facilitator Superfamily
AL543_RS02270	COG0579	oxidoreductase
AL543_RS02280	COG0242	peptide deformylase activity
AL543_RS02295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL543_RS02300	COG1609	Transcriptional regulator
AL543_RS02305	COG1017	nitric oxide dioxygenase activity
AL543_RS02305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL543_RS02315	COG0814	amino acid
AL543_RS02330	COG3530	Putative quorum-sensing-regulated virulence factor
AL543_RS02340	COG5001	Diguanylate cyclase
AL543_RS02340	COG5002	protein histidine kinase activity
AL543_RS02345	COG1278	Cold shock
AL543_RS02360	COG3335	DDE superfamily endonuclease
AL543_RS02380	COG2304	oxidoreductase activity
AL543_RS02400	COG0714	Associated with various cellular activities
AL543_RS02420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL543_RS02425	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL543_RS02435	COG3604	Transcriptional regulator
AL543_RS02440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL543_RS02440	COG1017	nitric oxide dioxygenase activity
AL543_RS02445	COG1278	Cold shock
AL543_RS02450	COG3036	rescue of stalled ribosome
AL543_RS02475	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL543_RS02475	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL543_RS02480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL543_RS02490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL543_RS02505	COG0516	GMP reductase activity
AL543_RS02510	COG4974	Belongs to the 'phage' integrase family
AL543_RS02605	COG4695	Portal protein
AL543_RS02735	COG0516	GMP reductase activity
AL543_RS02740	COG0513	Belongs to the DEAD box helicase family
AL543_RS02745	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL543_RS02750	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AL543_RS02755	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL543_RS02760	COG0840	transmembrane signaling receptor activity
AL543_RS02765	COG3437	response regulator, receiver
AL543_RS02765	COG0784	Response regulator, receiver
AL543_RS02770	COG4191	Histidine kinase
AL543_RS02770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL543_RS02780	COG1757	Na H antiporter
AL543_RS02785	COG2814	Major facilitator Superfamily
AL543_RS02795	COG3706	GGDEF domain
AL543_RS02800	COG3240	lipase activity
AL543_RS02810	COG0840	transmembrane signaling receptor activity
AL543_RS02835	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL543_RS02840	COG4605	iron ion homeostasis
AL543_RS02845	COG4604	ABC transporter, ATP-binding protein
AL543_RS02865	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL543_RS02880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL543_RS02880	COG1263	PTS System
AL543_RS02890	COG2149	membrane
AL543_RS02905	COG3623	hexulose-6-phosphate isomerase
AL543_RS02910	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AL543_RS02915	COG0561	phosphatase activity
AL543_RS02945	COG3335	DDE superfamily endonuclease
AL543_RS02955	COG3335	DDE superfamily endonuclease
AL543_RS02960	COG4154	Belongs to the RbsD FucU family
AL543_RS02965	COG0235	Class ii aldolase
AL543_RS02980	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL543_RS03025	COG3397	chitin binding
AL543_RS03030	COG3046	protein related to deoxyribodipyrimidine photolyase
AL543_RS03040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL543_RS03055	COG0513	Belongs to the DEAD box helicase family
AL543_RS03065	COG1368	sulfuric ester hydrolase activity
AL543_RS03070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL543_RS03105	COG0484	heat shock protein binding
AL543_RS03115	COG5001	Diguanylate cyclase
AL543_RS03115	COG1716	ATPase activity
AL543_RS03120	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL543_RS03130	COG4181	ATPase activity
AL543_RS03135	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL543_RS03150	COG1984	allophanate hydrolase subunit 2
AL543_RS03155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL543_RS03160	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL543_RS03165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL543_RS03175	COG0814	amino acid
AL543_RS03185	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AL543_RS03190	COG0513	Belongs to the DEAD box helicase family
AL543_RS03205	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL543_RS03210	COG0494	nUDIX hydrolase
AL543_RS03220	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AL543_RS03230	COG1126	abc transporter atp-binding protein
AL543_RS03235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL543_RS03240	COG4215	(ABC) transporter
AL543_RS03245	COG4160	amino acid transport
AL543_RS03250	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL543_RS03255	COG0583	DNA-binding transcription factor activity
AL543_RS03260	COG3335	DDE superfamily endonuclease
AL543_RS03275	COG0243	molybdopterin cofactor binding
AL543_RS03300	COG0477	Major facilitator Superfamily
AL543_RS03305	COG3118	belongs to the thioredoxin family
AL543_RS03310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL543_RS03320	COG1215	transferase activity, transferring glycosyl groups
AL543_RS03330	COG0247	lactate metabolic process
AL543_RS03335	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AL543_RS03340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL543_RS03350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL543_RS03355	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL543_RS03365	COG2926	Belongs to the UPF0265 family
AL543_RS03380	COG3335	DDE superfamily endonuclease
AL543_RS03385	COG2827	Endonuclease containing a URI domain
AL543_RS03395	COG1879	ABC-type sugar transport system periplasmic component
AL543_RS03400	COG0784	Response regulator, receiver
AL543_RS03400	COG5002	protein histidine kinase activity
AL543_RS03420	COG1492	cobalamin metabolic process
AL543_RS03425	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL543_RS03430	COG4149	molybdate abc transporter
AL543_RS03435	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL543_RS03455	COG1289	transmembrane transporter activity
AL543_RS03460	COG0210	DNA helicase
AL543_RS03485	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL543_RS03490	COG3335	DDE superfamily endonuclease
AL543_RS03500	COG1335	isochorismatase
AL543_RS03505	COG1803	Methylglyoxal synthase
AL543_RS03510	COG1879	ABC-type sugar transport system periplasmic component
AL543_RS03515	COG2205	protein histidine kinase activity
AL543_RS03515	COG2198	Histidine kinase
AL543_RS03515	COG0784	Response regulator, receiver
AL543_RS03520	COG0469	pyruvate kinase activity
AL543_RS03525	COG2271	Major facilitator Superfamily
AL543_RS03540	COG4191	Histidine kinase
AL543_RS03565	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL543_RS03585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL543_RS03590	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL543_RS03600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL543_RS03605	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL543_RS03625	COG0183	Belongs to the thiolase family
AL543_RS03635	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL543_RS03645	COG0583	DNA-binding transcription factor activity
AL543_RS03665	COG4964	Belongs to the GSP D family
AL543_RS03720	COG3842	ATPase activity
AL543_RS03730	COG1840	ABC-type Fe3 transport system, periplasmic component
AL543_RS03735	COG2271	Major facilitator Superfamily
AL543_RS03740	COG3851	Histidine kinase
AL543_RS03745	COG2197	response regulator
AL543_RS03750	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL543_RS03760	COG3005	denitrification pathway
AL543_RS03770	COG0243	molybdopterin cofactor binding
AL543_RS03780	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL543_RS03780	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL543_RS03785	COG3850	Histidine kinase
AL543_RS03790	COG2197	response regulator
AL543_RS03795	COG1760	l-serine dehydratase
AL543_RS03800	COG3069	C4-dicarboxylate transmembrane transporter activity
AL543_RS03805	COG0840	transmembrane signaling receptor activity
AL543_RS03810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL543_RS03815	COG0545	Peptidyl-prolyl cis-trans isomerase
AL543_RS03825	COG0840	transmembrane signaling receptor activity
AL543_RS03830	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL543_RS03945	COG0583	DNA-binding transcription factor activity
AL543_RS03980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL543_RS04010	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL543_RS04025	COG2390	Transcriptional regulator
AL543_RS04035	COG2897	thiosulfate sulfurtransferase activity
AL543_RS04045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL543_RS04055	COG0302	gtp cyclohydrolase
AL543_RS04060	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL543_RS04060	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL543_RS04065	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AL543_RS04070	COG1970	mechanosensitive ion channel activity
AL543_RS04075	COG1454	alcohol dehydrogenase
AL543_RS04080	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL543_RS04095	COG1011	Hydrolase
AL543_RS04100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL543_RS04105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL543_RS04110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL543_RS04115	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL543_RS04120	COG1840	ABC-type Fe3 transport system, periplasmic component
AL543_RS04125	COG3842	ATPase activity
AL543_RS04145	COG3104	oligopeptide transport
AL543_RS04170	COG4166	transmembrane transport
AL543_RS04175	COG4174	ABC transporter (Permease)
AL543_RS04180	COG4239	(ABC) transporter, permease
AL543_RS04185	COG4172	Belongs to the ABC transporter superfamily
AL543_RS04195	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL543_RS04210	COG0625	glutathione transferase activity
AL543_RS04230	COG2050	protein possibly involved in aromatic compounds catabolism
AL543_RS04245	COG4771	TonB-dependent receptor
AL543_RS04250	COG0583	DNA-binding transcription factor activity
AL543_RS04255	COG0045	succinate-CoA ligase (ADP-forming) activity
AL543_RS04255	COG1042	CoA-binding domain protein
AL543_RS04255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL543_RS04275	COG0023	Translation Initiation Factor
AL543_RS04285	COG1132	(ABC) transporter
AL543_RS04290	COG1132	(ABC) transporter
AL543_RS04295	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL543_RS04320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL543_RS04320	COG2226	methyltransferase
AL543_RS04320	COG3433	isochorismatase activity
AL543_RS04325	COG2814	Major facilitator Superfamily
AL543_RS04330	COG4771	TonB-dependent receptor
AL543_RS04395	COG3140	Belongs to the UPF0181 family
AL543_RS04420	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL543_RS04425	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL543_RS04460	COG3706	GGDEF domain
AL543_RS04495	COG2824	Alkylphosphonate utilization operon protein PhnA
AL543_RS04510	COG0737	Belongs to the 5'-nucleotidase family
AL543_RS04515	COG3593	DNA synthesis involved in DNA repair
AL543_RS04525	COG0583	DNA-binding transcription factor activity
AL543_RS04530	COG2116	formate transmembrane transporter activity
AL543_RS04540	COG3038	cytochrome b561
AL543_RS04550	COG5001	Diguanylate cyclase
AL543_RS04550	COG3300	MHYT domain
AL543_RS04575	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
AL543_RS04580	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
AL543_RS04585	COG1737	Transcriptional regulator
AL543_RS04590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL543_RS04595	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL543_RS04600	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL543_RS04605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL543_RS04620	COG1940	carbohydrate kinase activity
AL543_RS04625	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL543_RS04630	COG3335	DDE superfamily endonuclease
AL543_RS04635	COG4409	exo-alpha-(2->6)-sialidase activity
AL543_RS04640	COG3335	DDE superfamily endonuclease
AL543_RS04645	COG4409	exo-alpha-(2->6)-sialidase activity
AL543_RS04655	COG0523	cobalamin synthesis protein
AL543_RS04660	COG0038	chloride channel
AL543_RS04675	COG0156	8-amino-7-oxononanoate synthase activity
AL543_RS04680	COG0784	Response regulator, receiver
AL543_RS04680	COG2205	protein histidine kinase activity
AL543_RS04685	COG0419	ATPase involved in DNA repair
AL543_RS04690	COG0420	3'-5' exonuclease activity
AL543_RS04695	COG1609	Transcriptional regulator
AL543_RS04700	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL543_RS04700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL543_RS04705	COG1105	Belongs to the carbohydrate kinase PfkB family
AL543_RS04710	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL543_RS04710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL543_RS04710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL543_RS04715	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL543_RS04720	COG4067	protein conserved in archaea
AL543_RS04720	COG0189	ligase activity
AL543_RS04730	COG0602	queuosine metabolic process
AL543_RS04735	COG1328	CTP reductase activity
AL543_RS04745	COG1917	Cupin 2, conserved barrel domain protein
AL543_RS04745	COG4977	sequence-specific DNA binding
AL543_RS04755	COG3335	DDE superfamily endonuclease
AL543_RS04815	COG0346	lactoylglutathione lyase activity
AL543_RS04825	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL543_RS04845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL543_RS04870	COG3335	DDE superfamily endonuclease
AL543_RS05155	COG3335	DDE superfamily endonuclease
AL543_RS05200	COG4628	conserved protein (DUF2132)
AL543_RS05220	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL543_RS05270	COG0110	maltose O-acetyltransferase activity
AL543_RS05280	COG3093	addiction module antidote protein HigA
AL543_RS05285	COG3549	Plasmid maintenance system killer
AL543_RS05290	COG0346	lactoylglutathione lyase activity
AL543_RS05360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL543_RS05380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL543_RS05490	COG4115	mRNA cleavage
AL543_RS05495	COG2161	toxin-antitoxin pair type II binding
AL543_RS05550	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL543_RS05550	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL543_RS05565	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL543_RS05575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL543_RS05635	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AL543_RS05640	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL543_RS05655	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL543_RS05665	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL543_RS05670	COG0509	glycine decarboxylation via glycine cleavage system
AL543_RS05675	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL543_RS05675	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL543_RS05680	COG2755	lipolytic protein G-D-S-L family
AL543_RS05685	COG3338	carbonate dehydratase activity
AL543_RS05700	COG1686	Belongs to the peptidase S11 family
AL543_RS05705	COG1414	Transcriptional regulator
AL543_RS05720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL543_RS05725	COG0601	transmembrane transport
AL543_RS05740	COG0641	radical SAM
AL543_RS05745	COG3119	arylsulfatase activity
AL543_RS05750	COG3119	arylsulfatase activity
AL543_RS05755	COG2199	diguanylate cyclase activity
AL543_RS05775	COG1028	Short-chain dehydrogenase reductase Sdr
AL543_RS05780	COG1085	galactose-1-phosphate uridylyltransferase
AL543_RS05785	COG0800	Aldolase
AL543_RS05790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL543_RS05810	COG1166	arginine decarboxylase activity
AL543_RS05835	COG2239	Acts as a magnesium transporter
AL543_RS05840	COG0527	aspartate kinase activity
AL543_RS05845	COG0662	Cupin 2, conserved barrel domain protein
AL543_RS05850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL543_RS05855	COG0456	acetyltransferase
AL543_RS05870	COG0534	Mate efflux family protein
AL543_RS05880	COG2154	pterin-4-alpha-carbinolamine dehydratase
AL543_RS05885	COG3186	Phenylalanine-4-hydroxylase
AL543_RS05890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL543_RS05905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL543_RS05920	COG1253	flavin adenine dinucleotide binding
AL543_RS05925	COG1765	OsmC-like protein
AL543_RS05935	COG5001	Diguanylate cyclase
AL543_RS05955	COG0531	amino acid
AL543_RS05970	COG3279	Response regulator of the LytR AlgR family
AL543_RS05975	COG3275	phosphorelay sensor kinase activity
AL543_RS05990	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL543_RS05995	COG1136	(ABC) transporter
AL543_RS06005	COG4989	oxidoreductase activity
AL543_RS06010	COG0366	Alpha amylase catalytic
AL543_RS06015	COG3335	DDE superfamily endonuclease
AL543_RS06040	COG3227	Zinc metalloprotease (Elastase)
AL543_RS06050	COG3047	cAMP biosynthetic process
AL543_RS06060	COG1686	Belongs to the peptidase S11 family
AL543_RS06925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL543_RS07050	COG0531	amino acid
AL543_RS07135	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL543_RS07135	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL543_RS07135	COG0506	proline dehydrogenase activity
AL543_RS07450	COG2909	trisaccharide binding
AL543_RS07460	COG2909	trisaccharide binding
AL543_RS07835	COG0840	transmembrane signaling receptor activity
AL543_RS08025	COG0246	Mannitol dehydrogenase
AL543_RS08220	COG1301	dicarboxylic acid transport
AL543_RS08365	COG3829	transcription factor binding
AL543_RS08460	COG0584	glycerophosphoryl diester phosphodiesterase
AL543_RS08695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL543_RS09390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL543_RS09500	COG0814	amino acid
AL543_RS09525	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL543_RS09595	COG0243	molybdopterin cofactor binding
AL543_RS09720	COG0784	Response regulator, receiver
AL543_RS09720	COG5002	protein histidine kinase activity
AL543_RS09785	COG0210	DNA helicase
AL543_RS09790	COG0210	DNA helicase
AL543_RS09890	COG4191	Histidine kinase
AL543_RS09970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL543_RS10605	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL543_RS10745	COG3433	isochorismatase activity
AL543_RS10745	COG2226	methyltransferase
AL543_RS10745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL543_RS10980	COG0750	zinc metalloprotease
AL543_RS12220	COG1166	arginine decarboxylase activity
AL543_RS12370	COG0531	amino acid
AL543_RS12510	COG3227	Zinc metalloprotease (Elastase)
AL543_RS12575	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL543_RS12650	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL543_RS12770	COG2813	Specifically methylates the guanine in position
AL543_RS12920	COG0189	ligase activity
AL543_RS12920	COG0569	domain protein
AL543_RS13180	COG0070	glutamate synthase
AL543_RS13180	COG0069	glutamate synthase activity
AL543_RS13180	COG0067	glutamate synthase
AL543_RS13255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL543_RS13320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL543_RS13410	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL543_RS13840	COG0473	3-isopropylmalate dehydrogenase activity
AL543_RS13905	COG3437	response regulator, receiver
AL543_RS14210	COG0545	Peptidyl-prolyl cis-trans isomerase
AL543_RS14320	COG1047	Peptidyl-prolyl cis-trans
AL543_RS14525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL543_RS14810	COG3263	regulation of cellular component size
AL543_RS14825	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL543_RS14840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL543_RS15265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL543_RS15440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL543_RS15440	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL543_RS15690	COG0006	proline dipeptidase activity
AL543_RS15740	COG0582	viral genome integration into host DNA
AL543_RS16015	COG0751	glycine-tRNA ligase activity
AL543_RS16350	COG0210	DNA helicase
AL543_RS16650	COG1216	Glycosyl transferase, family 2
AL543_RS16650	COG1442	glycosyl transferase family 8
AL543_RS16675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL543_RS16725	COG0138	bifunctional purine biosynthesis protein purh
AL543_RS16855	COG0248	Ppx GppA phosphatase
AL543_RS17020	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL543_RS17055	COG4942	peptidase
AL543_RS17100	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL543_RS17370	COG2200	EAL domain
AL543_RS17370	COG2199	diguanylate cyclase activity
AL543_RS17490	COG1151	hydroxylamine reductase activity
AL543_RS17660	COG0741	lytic transglycosylase activity
AL543_RS17730	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL543_RS17780	COG4771	TonB-dependent receptor
AL543_RS17795	COG0126	phosphoglycerate kinase activity
AL543_RS17960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL543_RS17965	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL543_RS17970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL543_RS18000	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AL543_RS18180	COG1643	Atp-dependent helicase
AL543_RS18415	COG0779	Required for maturation of 30S ribosomal subunits
AL543_RS18570	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AL543_RS19020	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL543_RS19120	COG1074	ATP-dependent DNA helicase activity
AL543_RS19510	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL543_RS19510	COG0047	phosphoribosylformylglycinamidine synthase activity
AL543_RS19605	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL543_RS19950	COG0768	penicillin binding
AL543_RS20055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA