locus-tag	class	description
BA893_RS00010	COG0592	DNA-directed DNA polymerase activity
BA893_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BA893_RS00020	COG0187	DNA topoisomerase II activity
BA893_RS00030	COG0071	Belongs to the small heat shock protein (HSP20) family
BA893_RS00035	COG3977	Valine--pyruvate aminotransferase
BA893_RS00040	COG0366	Alpha amylase catalytic
BA893_RS00045	COG0751	glycine-tRNA ligase activity
BA893_RS00055	COG2119	membrane
BA893_RS00065	COG0425	Belongs to the sulfur carrier protein TusA family
BA893_RS00080	COG0604	alcohol dehydrogenase
BA893_RS00085	COG0183	Belongs to the thiolase family
BA893_RS00090	COG1024	Enoyl-CoA hydratase
BA893_RS00090	COG1250	3-hydroxyacyl-CoA dehydrogenase
BA893_RS00095	COG1739	Uncharacterized protein family UPF0029
BA893_RS00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BA893_RS00145	COG0583	DNA-binding transcription factor activity
BA893_RS00150	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BA893_RS00155	COG2960	long-chain fatty acid transporting porin activity
BA893_RS00160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA893_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA893_RS00170	COG1309	transcriptional regulator
BA893_RS00220	COG4166	transmembrane transport
BA893_RS00225	COG0601	transmembrane transport
BA893_RS00230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA893_RS00240	COG1609	Transcriptional regulator
BA893_RS00245	COG0129	dihydroxy-acid dehydratase activity
BA893_RS00250	COG3265	gluconokinase activity
BA893_RS00255	COG2610	gluconate transmembrane transporter activity
BA893_RS00260	COG0800	Aldolase
BA893_RS00265	COG3721	Heme iron utilization protein
BA893_RS00270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BA893_RS00275	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BA893_RS00285	COG1522	sequence-specific DNA binding
BA893_RS00290	COG0742	ribosomal rna small subunit methyltransferase
BA893_RS00305	COG0589	response to stress
BA893_RS00310	COG1528	Iron-storage protein
BA893_RS00320	COG2081	HI0933 family
BA893_RS00345	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BA893_RS00350	COG0732	type I restriction modification DNA specificity domain
BA893_RS00365	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BA893_RS00410	COG0235	Class ii aldolase
BA893_RS00415	COG3395	kinase activity
BA893_RS00430	COG3181	Tripartite tricarboxylate transporter family receptor
BA893_RS00435	COG0473	3-isopropylmalate dehydrogenase activity
BA893_RS00450	COG2814	Major facilitator Superfamily
BA893_RS00455	COG0583	DNA-binding transcription factor activity
BA893_RS00460	COG1522	sequence-specific DNA binding
BA893_RS00465	COG2962	Rard protein
BA893_RS00475	COG1028	Short-chain dehydrogenase reductase Sdr
BA893_RS00485	COG0583	DNA-binding transcription factor activity
BA893_RS00510	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BA893_RS00510	COG0515	serine threonine protein kinase
BA893_RS00575	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BA893_RS00600	COG1028	Short-chain dehydrogenase reductase Sdr
BA893_RS00630	COG4964	Belongs to the GSP D family
BA893_RS00680	COG0748	coenzyme F420 binding
BA893_RS00690	COG4988	ABC transporter
BA893_RS00695	COG1132	(ABC) transporter
BA893_RS00715	COG1322	Protein conserved in bacteria
BA893_RS00720	COG2226	methyltransferase
BA893_RS00725	COG3165	ubiquinone biosynthetic process from chorismate
BA893_RS00730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BA893_RS00740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BA893_RS00745	COG0805	protein transport
BA893_RS00750	COG3263	regulation of cellular component size
BA893_RS00755	COG0084	hydrolase, TatD family'
BA893_RS00775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BA893_RS00775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BA893_RS00780	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BA893_RS00810	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BA893_RS00820	COG2204	response regulator
BA893_RS00825	COG3852	Histidine kinase
BA893_RS00835	COG0174	glutamine synthetase
BA893_RS00840	COG1217	gtp-binding protein TYPA
BA893_RS00855	COG1295	ribonuclease BN
BA893_RS00860	COG1490	D-aminoacyl-tRNA deacylase activity
BA893_RS00865	COG0456	acetyltransferase
BA893_RS00875	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BA893_RS00880	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BA893_RS00885	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BA893_RS00890	COG3031	protein transport across the cell outer membrane
BA893_RS00900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BA893_RS00905	COG1459	type II secretion system
BA893_RS00910	COG2165	general secretion pathway protein
BA893_RS00915	COG2165	general secretion pathway protein
BA893_RS00920	COG2165	general secretion pathway protein
BA893_RS00925	COG4795	General secretion pathway protein
BA893_RS00930	COG3156	type II secretion system protein K
BA893_RS00935	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BA893_RS00940	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BA893_RS00950	COG1218	3'(2'),5'-bisphosphate nucleotidase
BA893_RS00955	COG0494	nUDIX hydrolase
BA893_RS00965	COG1040	competence protein
BA893_RS00970	COG0596	Alpha beta hydrolase
BA893_RS00980	COG2183	response to ionizing radiation
BA893_RS00990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BA893_RS01010	COG2233	PERMEase
BA893_RS01015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BA893_RS01020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BA893_RS01025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BA893_RS01030	COG1758	RNA polymerase activity
BA893_RS01035	COG0194	GDP metabolic process
BA893_RS01050	COG0848	biopolymer transport protein
BA893_RS01055	COG0811	peptide transport
BA893_RS01075	COG4174	ABC transporter (Permease)
BA893_RS01080	COG4239	(ABC) transporter, permease
BA893_RS01085	COG0747	negative chemotaxis
BA893_RS01090	COG0444	Belongs to the ABC transporter superfamily
BA893_RS01095	COG4608	Belongs to the ABC transporter superfamily
BA893_RS01120	COG1561	YicC-like family, N-terminal region
BA893_RS01125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BA893_RS01130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BA893_RS01135	COG1560	Kdo2-lipid A biosynthetic process
BA893_RS01140	COG1309	transcriptional regulator
BA893_RS01145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BA893_RS01150	COG0840	transmembrane signaling receptor activity
BA893_RS01155	COG2003	Belongs to the UPF0758 family
BA893_RS01175	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BA893_RS01190	COG0438	transferase activity, transferring glycosyl groups
BA893_RS01195	COG0463	Glycosyl transferase, family 2
BA893_RS01200	COG0859	PFAM glycosyl transferase family 9
BA893_RS01205	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BA893_RS01210	COG3642	lipopolysaccharide core region biosynthetic process
BA893_RS01215	COG1086	Polysaccharide biosynthesis protein
BA893_RS01220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BA893_RS01225	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BA893_RS01230	COG2089	acid synthase
BA893_RS01240	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BA893_RS01245	COG1083	cytidylyl-transferase
BA893_RS01255	COG1519	Transferase
BA893_RS01260	COG0859	PFAM glycosyl transferase family 9
BA893_RS01265	COG1560	Kdo2-lipid A biosynthetic process
BA893_RS01275	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BA893_RS01345	COG0438	transferase activity, transferring glycosyl groups
BA893_RS01355	COG0110	maltose O-acetyltransferase activity
BA893_RS01360	COG0438	transferase activity, transferring glycosyl groups
BA893_RS01370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BA893_RS01385	COG0489	protein tyrosine kinase activity
BA893_RS01385	COG3206	protein involved in exopolysaccharide biosynthesis
BA893_RS01425	COG0438	transferase activity, transferring glycosyl groups
BA893_RS01430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BA893_RS01440	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BA893_RS01460	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BA893_RS01465	COG0149	triose-phosphate isomerase activity
BA893_RS01475	COG3152	Membrane
BA893_RS01490	COG1494	fructose-1,6-bisphosphatase
BA893_RS01500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BA893_RS01505	COG1575	Belongs to the MenA family. Type 1 subfamily
BA893_RS01510	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BA893_RS01525	COG1609	Transcriptional regulator
BA893_RS01530	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BA893_RS01535	COG0254	rRNA binding
BA893_RS01545	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BA893_RS01550	COG0088	Forms part of the polypeptide exit tunnel
BA893_RS01560	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BA893_RS01565	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BA893_RS01570	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BA893_RS01575	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BA893_RS01585	COG0255	Belongs to the universal ribosomal protein uL29 family
BA893_RS01590	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BA893_RS01600	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BA893_RS01605	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BA893_RS01620	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BA893_RS01635	COG1841	ribosomal large subunit assembly
BA893_RS01640	COG0200	Binds to the 23S rRNA
BA893_RS01645	COG0201	protein transport
BA893_RS01650	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BA893_RS01655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BA893_RS01660	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BA893_RS01670	COG0202	RNA polymerase activity
BA893_RS01675	COG0203	ribosomal protein L17
BA893_RS01685	COG0545	Peptidyl-prolyl cis-trans isomerase
BA893_RS01695	COG2153	protein acetylation
BA893_RS01700	COG0513	Belongs to the DEAD box helicase family
BA893_RS01710	COG0737	Belongs to the 5'-nucleotidase family
BA893_RS01715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BA893_RS01715	COG1648	precorrin-2 dehydrogenase activity
BA893_RS01720	COG0175	sulfate reduction
BA893_RS01725	COG2895	sulfate adenylyltransferase (ATP) activity
BA893_RS01735	COG3273	potassium ion transport
BA893_RS01735	COG0471	metal ion transport
BA893_RS01740	COG0529	Catalyzes the synthesis of activated sulfate
BA893_RS01760	COG1136	(ABC) transporter
BA893_RS01775	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BA893_RS01785	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BA893_RS01795	COG2911	Protein conserved in bacteria
BA893_RS01800	COG2105	PFAM AIG2 family protein
BA893_RS01805	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BA893_RS01810	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BA893_RS01815	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BA893_RS01820	COG0163	prenyltransferase activity
BA893_RS01830	COG1178	ABC-type Fe3 transport system permease component
BA893_RS01835	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BA893_RS01860	COG0039	L-malate dehydrogenase activity
BA893_RS01870	COG0142	geranyltranstransferase activity
BA893_RS01875	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BA893_RS01885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BA893_RS01890	COG2966	Psort location CytoplasmicMembrane, score
BA893_RS01900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BA893_RS01910	COG2967	ApaG domain
BA893_RS01915	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BA893_RS01920	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BA893_RS01925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA893_RS01930	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BA893_RS01935	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BA893_RS01945	COG0066	3-isopropylmalate dehydratase activity
BA893_RS01955	COG0473	3-isopropylmalate dehydrogenase activity
BA893_RS01960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BA893_RS01970	COG0671	phosphoesterase, PA-phosphatase related
BA893_RS01980	COG0583	DNA-binding transcription factor activity
BA893_RS01985	COG1022	Amp-dependent synthetase and ligase
BA893_RS01990	COG0028	Belongs to the TPP enzyme family
BA893_RS01995	COG0440	acetolactate synthase activity
BA893_RS02000	COG0469	pyruvate kinase activity
BA893_RS02005	COG1349	DNA-binding transcription factor activity
BA893_RS02010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BA893_RS02020	COG1263	PTS System
BA893_RS02020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA893_RS02025	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BA893_RS02030	COG3722	fumarate hydratase activity
BA893_RS02035	COG0246	Mannitol dehydrogenase
BA893_RS02040	COG2213	PTS system mannitol-specific
BA893_RS02040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA893_RS02075	COG1464	Belongs to the NlpA lipoprotein family
BA893_RS02080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BA893_RS02100	COG0358	DNA primase activity
BA893_RS02105	COG1610	YqeY-like protein
BA893_RS02110	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BA893_RS02115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BA893_RS02120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BA893_RS02125	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BA893_RS02130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BA893_RS02135	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BA893_RS02140	COG1968	undecaprenyl-diphosphatase activity
BA893_RS02145	COG0617	tRNA 3'-terminal CCA addition
BA893_RS02150	COG3267	Type II secretory pathway component ExeA
BA893_RS02150	COG3409	Peptidoglycan-binding domain 1 protein
BA893_RS02160	COG4991	sh3 domain protein
BA893_RS02165	COG0306	phosphate transporter
BA893_RS02170	COG1392	Phosphate transport regulator
BA893_RS02175	COG3025	triphosphatase activity
BA893_RS02190	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BA893_RS02200	COG1538	Outer membrane efflux protein
BA893_RS02205	COG0494	nUDIX hydrolase
BA893_RS02210	COG3151	Protein conserved in bacteria
BA893_RS02220	COG3150	esterase
BA893_RS02230	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BA893_RS02235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BA893_RS02245	COG3105	Protein conserved in bacteria
BA893_RS02250	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BA893_RS02255	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BA893_RS02260	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BA893_RS02265	COG0723	plastoquinol--plastocyanin reductase activity
BA893_RS02270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BA893_RS02275	COG2857	Cytochrome c1
BA893_RS02280	COG0625	glutathione transferase activity
BA893_RS02285	COG2969	positive regulation of protein catabolic process
BA893_RS02290	COG2823	Periplasmic or secreted lipoprotein
BA893_RS02295	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BA893_RS02310	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BA893_RS02320	COG0275	rRNA processing
BA893_RS02325	COG3116	cell division
BA893_RS02330	COG0768	penicillin binding
BA893_RS02335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BA893_RS02340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BA893_RS02345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BA893_RS02350	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BA893_RS02355	COG0772	Belongs to the SEDS family
BA893_RS02360	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BA893_RS02365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BA893_RS02370	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BA893_RS02375	COG0849	cell division
BA893_RS02380	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BA893_RS02385	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BA893_RS02395	COG0653	protein targeting
BA893_RS02400	COG0494	nUDIX hydrolase
BA893_RS02410	COG0505	Belongs to the CarA family
BA893_RS02415	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BA893_RS02420	COG0730	response to heat
BA893_RS02425	COG0583	DNA-binding transcription factor activity
BA893_RS02430	COG2860	membrane
BA893_RS02435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BA893_RS02445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BA893_RS02455	COG0493	'glutamate synthase
BA893_RS02460	COG0070	glutamate synthase
BA893_RS02460	COG0069	glutamate synthase activity
BA893_RS02460	COG0067	glutamate synthase
BA893_RS02470	COG0069	glutamate synthase activity
BA893_RS02470	COG0070	glutamate synthase
BA893_RS02470	COG0067	glutamate synthase
BA893_RS02475	COG1242	4 iron, 4 sulfur cluster binding
BA893_RS02480	COG0784	Response regulator, receiver
BA893_RS02480	COG5002	protein histidine kinase activity
BA893_RS02480	COG2198	Histidine kinase
BA893_RS02490	COG0745	RESPONSE REGULATOR receiver
BA893_RS02500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BA893_RS02515	COG0083	homoserine kinase activity
BA893_RS02520	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BA893_RS02525	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
BA893_RS02530	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BA893_RS02535	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BA893_RS02550	COG1115	amino acid carrier protein
BA893_RS02555	COG3022	response to hydroperoxide
BA893_RS02560	COG0513	Belongs to the DEAD box helicase family
BA893_RS02565	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BA893_RS02580	COG4974	Belongs to the 'phage' integrase family
BA893_RS02585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BA893_RS02590	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BA893_RS02595	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BA893_RS02600	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BA893_RS02605	COG3290	protein histidine kinase activity
BA893_RS02605	COG3829	transcription factor binding
BA893_RS02615	COG0667	Aldo Keto reductase
BA893_RS02625	COG3066	DNA modification
BA893_RS02640	COG0730	response to heat
BA893_RS02645	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BA893_RS02650	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BA893_RS02660	COG1283	sodium-dependent phosphate transmembrane transporter activity
BA893_RS02665	COG0583	DNA-binding transcription factor activity
BA893_RS02670	COG0640	Transcriptional regulator
BA893_RS02675	COG0268	Binds directly to 16S ribosomal RNA
BA893_RS02680	COG0728	peptidoglycan biosynthetic process
BA893_RS02685	COG0196	riboflavin kinase activity
BA893_RS02690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BA893_RS02695	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BA893_RS02700	COG1047	Peptidyl-prolyl cis-trans
BA893_RS02705	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BA893_RS02710	COG3279	Response regulator of the LytR AlgR family
BA893_RS02715	COG3275	phosphorelay sensor kinase activity
BA893_RS02720	COG1966	Carbon starvation protein
BA893_RS02740	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BA893_RS02745	COG1472	Belongs to the glycosyl hydrolase 3 family
BA893_RS02750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BA893_RS02755	COG0287	Prephenate dehydrogenase
BA893_RS02755	COG1605	Chorismate mutase
BA893_RS02760	COG0739	heme binding
BA893_RS02765	COG0488	(ABC) transporter
BA893_RS02775	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
BA893_RS02780	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BA893_RS02785	COG0077	Prephenate dehydratase
BA893_RS02785	COG1605	Chorismate mutase
BA893_RS02790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BA893_RS02795	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BA893_RS02800	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BA893_RS02805	COG0564	pseudouridine synthase activity
BA893_RS02815	COG0542	response to heat
BA893_RS02830	COG1116	anion transmembrane transporter activity
BA893_RS02895	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BA893_RS02900	COG0826	peptidase U32
BA893_RS02905	COG2974	May be involved in recombination
BA893_RS02915	COG0745	RESPONSE REGULATOR receiver
BA893_RS02920	COG5002	protein histidine kinase activity
BA893_RS02930	COG0248	Ppx GppA phosphatase
BA893_RS02935	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BA893_RS02945	COG0581	inorganic phosphate transmembrane transporter activity
BA893_RS02950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BA893_RS02955	COG0704	Plays a role in the regulation of phosphate uptake
BA893_RS02965	COG3142	Participates in the control of copper homeostasis
BA893_RS02970	COG0450	alkyl hydroperoxide reductase
BA893_RS02975	COG0583	DNA-binding transcription factor activity
BA893_RS02980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BA893_RS02990	COG0517	IMP dehydrogenase activity
BA893_RS03000	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BA893_RS03005	COG0343	queuine tRNA-ribosyltransferase activity
BA893_RS03010	COG1862	Preprotein translocase
BA893_RS03015	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BA893_RS03020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BA893_RS03025	COG0483	inositol monophosphate 1-phosphatase activity
BA893_RS03030	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BA893_RS03040	COG1104	cysteine desulfurase activity
BA893_RS03045	COG0822	iron-sulfur transferase activity
BA893_RS03060	COG0443	Heat shock 70 kDa protein
BA893_RS03065	COG0633	Ferredoxin
BA893_RS03070	COG2975	iron-sulfur cluster assembly
BA893_RS03075	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BA893_RS03080	COG0105	UTP biosynthetic process
BA893_RS03095	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BA893_RS03100	COG0124	histidyl-tRNA synthetase
BA893_RS03105	COG2976	Protein conserved in bacteria
BA893_RS03110	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BA893_RS03115	COG1160	GTP binding
BA893_RS03135	COG0517	IMP dehydrogenase activity
BA893_RS03135	COG0516	GMP reductase activity
BA893_RS03140	COG0519	Catalyzes the synthesis of GMP from XMP
BA893_RS03140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BA893_RS03155	COG1584	GPR1 FUN34 yaaH family protein
BA893_RS03170	COG1473	amidohydrolase
BA893_RS03180	COG1115	amino acid carrier protein
BA893_RS03185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA893_RS03195	COG2873	o-acetylhomoserine
BA893_RS03200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BA893_RS03220	COG3153	acetyltransferase
BA893_RS03220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BA893_RS03225	COG0583	DNA-binding transcription factor activity
BA893_RS03230	COG0235	Class ii aldolase
BA893_RS03235	COG4806	L-rhamnose isomerase
BA893_RS03240	COG1070	Carbohydrate kinase
BA893_RS03245	COG3254	rhamnose metabolic process
BA893_RS03275	COG1404	Belongs to the peptidase S8 family
BA893_RS03290	COG3850	Histidine kinase
BA893_RS03370	COG0582	viral genome integration into host DNA
BA893_RS03380	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BA893_RS03385	COG2867	negative regulation of translational initiation
BA893_RS03390	COG2914	Belongs to the UPF0125 (RnfH) family
BA893_RS03395	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BA893_RS03400	COG0497	DNA recombination
BA893_RS03405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BA893_RS03410	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BA893_RS03415	COG1301	dicarboxylic acid transport
BA893_RS03425	COG0484	heat shock protein binding
BA893_RS03455	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BA893_RS03465	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BA893_RS03470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BA893_RS03470	COG0047	phosphoribosylformylglycinamidine synthase activity
BA893_RS03495	COG2195	Cleaves the N-terminal amino acid of tripeptides
BA893_RS03500	COG2252	PERMEase
BA893_RS03505	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BA893_RS03510	COG1073	alpha beta
BA893_RS03520	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BA893_RS03525	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BA893_RS03530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BA893_RS03535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BA893_RS03535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BA893_RS03550	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BA893_RS03560	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BA893_RS03565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BA893_RS03575	COG0142	geranyltranstransferase activity
BA893_RS03585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BA893_RS03590	COG2885	chlorophyll binding
BA893_RS03595	COG0301	tRNA thio-modification
BA893_RS03595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA893_RS03600	COG0583	DNA-binding transcription factor activity
BA893_RS03610	COG2363	Small membrane protein
BA893_RS03615	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BA893_RS03620	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BA893_RS03625	COG1611	Belongs to the LOG family
BA893_RS03640	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BA893_RS03640	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BA893_RS03650	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BA893_RS03655	COG1464	Belongs to the NlpA lipoprotein family
BA893_RS03660	COG2011	ABC-type metal ion transport system permease component
BA893_RS03665	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BA893_RS03670	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BA893_RS03680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA893_RS03680	COG1263	PTS System
BA893_RS03685	COG0366	Alpha amylase catalytic
BA893_RS03695	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BA893_RS03700	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BA893_RS03705	COG0321	lipoyl(octanoyl) transferase activity
BA893_RS03715	COG1686	Belongs to the peptidase S11 family
BA893_RS03720	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BA893_RS03725	COG0772	Belongs to the SEDS family
BA893_RS03730	COG0768	penicillin binding
BA893_RS03740	COG0799	negative regulation of ribosome biogenesis
BA893_RS03745	COG1466	dna polymerase III delta subunit
BA893_RS03750	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BA893_RS03755	COG0495	leucyl-tRNA aminoacylation
BA893_RS03760	COG2888	peptidyl-tyrosine sulfation
BA893_RS03765	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BA893_RS03770	COG4535	Mg2 and Co2 transporter CorC
BA893_RS03780	COG1702	phosphate starvation-inducible protein PhoH
BA893_RS03785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BA893_RS03790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BA893_RS03900	COG0012	GTP binding
BA893_RS03910	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BA893_RS03915	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BA893_RS03920	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BA893_RS03925	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BA893_RS03935	COG2890	protein-(glutamine-N5) methyltransferase activity
BA893_RS03940	COG3094	Invasion gene expression up-regulator, SirB
BA893_RS03945	COG2912	Transglutaminase-like superfamily
BA893_RS03950	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BA893_RS03955	COG0737	Belongs to the 5'-nucleotidase family
BA893_RS03960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BA893_RS03965	COG1187	pseudouridine synthase activity
BA893_RS03970	COG2840	Smr protein MutS2
BA893_RS04000	COG2217	Heavy metal translocating P-type atpase
BA893_RS04000	COG2608	mercury ion transmembrane transporter activity
BA893_RS04055	COG0835	chemotaxis
BA893_RS04055	COG0784	Response regulator, receiver
BA893_RS04060	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BA893_RS04065	COG1815	bacterial-type flagellum-dependent cell motility
BA893_RS04070	COG1558	bacterial-type flagellum-dependent cell motility
BA893_RS04080	COG1749	Flagellar hook protein flgE
BA893_RS04085	COG4787	bacterial-type flagellum-dependent cell motility
BA893_RS04095	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BA893_RS04100	COG1706	bacterial-type flagellum-dependent cell motility
BA893_RS04105	COG3951	Flagellar rod assembly protein muramidase FlgJ
BA893_RS04105	COG1705	Flagellar rod assembly protein muramidase FlgJ
BA893_RS04115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BA893_RS04120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BA893_RS04125	COG2190	(PTS) system
BA893_RS04130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BA893_RS04135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA893_RS04140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BA893_RS04145	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BA893_RS04150	COG3115	cell septum assembly
BA893_RS04155	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BA893_RS04175	COG0330	HflC and HflK could
BA893_RS04180	COG3118	belongs to the thioredoxin family
BA893_RS04185	COG0300	oxidoreductase activity
BA893_RS04190	COG1090	epimerase
BA893_RS04220	COG0622	Phosphoesterase
BA893_RS04240	COG3710	Transcriptional regulator
BA893_RS04245	COG0326	Molecular chaperone. Has ATPase activity
BA893_RS04255	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BA893_RS04260	COG3104	oligopeptide transport
BA893_RS04265	COG0250	Participates in transcription elongation, termination and antitermination
BA893_RS04270	COG0367	asparagine synthase
BA893_RS04280	COG1940	carbohydrate kinase activity
BA893_RS04280	COG1846	Transcriptional regulator
BA893_RS04285	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BA893_RS04290	COG2190	(PTS) system
BA893_RS04290	COG1263	PTS System
BA893_RS04290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA893_RS04295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BA893_RS04300	COG0735	belongs to the Fur family
BA893_RS04320	COG0596	Alpha beta hydrolase
BA893_RS04325	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BA893_RS04330	COG0033	Phosphoglucomutase
BA893_RS04340	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BA893_RS04355	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BA893_RS04360	COG1053	succinate dehydrogenase
BA893_RS04370	COG0567	Dehydrogenase, E1 component
BA893_RS04375	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA893_RS04380	COG0045	succinate-CoA ligase (ADP-forming) activity
BA893_RS04390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BA893_RS04395	COG1121	(ABC) transporter
BA893_RS04400	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BA893_RS04405	COG4977	sequence-specific DNA binding
BA893_RS04410	COG2963	transposase activity
BA893_RS04415	COG2801	Transposase and inactivated derivatives
BA893_RS04420	COG1918	ferrous iron import across plasma membrane
BA893_RS04440	COG0018	arginyl-trna synthetase
BA893_RS04445	COG3102	Protein conserved in bacteria
BA893_RS04460	COG0788	formyltetrahydrofolate deformylase activity
BA893_RS04465	COG1199	ATP-dependent helicase activity
BA893_RS04470	COG1214	PFAM Peptidase M22, glycoprotease
BA893_RS04485	COG2267	carboxylic ester hydrolase activity
BA893_RS04490	COG0318	PFAM AMP-dependent synthetase and ligase
BA893_RS04495	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BA893_RS04500	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BA893_RS04505	COG2894	cell division
BA893_RS04520	COG2951	lytic endotransglycosylase activity
BA893_RS04525	COG0583	DNA-binding transcription factor activity
BA893_RS04530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA893_RS04535	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BA893_RS04545	COG1028	Short-chain dehydrogenase reductase Sdr
BA893_RS04555	COG1169	isochorismate synthase
BA893_RS04560	COG1021	2,3-dihydroxybenzoate-AMP ligase
BA893_RS04565	COG3433	isochorismatase activity
BA893_RS04565	COG1535	isochorismatase
BA893_RS04570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BA893_RS04585	COG4771	TonB-dependent receptor
BA893_RS04590	COG1253	flavin adenine dinucleotide binding
BA893_RS04595	COG0513	Belongs to the DEAD box helicase family
BA893_RS04600	COG0569	domain protein
BA893_RS04605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BA893_RS04615	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BA893_RS04635	COG1175	transmembrane transport
BA893_RS04640	COG0395	ABC-type sugar transport system, permease component
BA893_RS04645	COG3842	ATPase activity
BA893_RS04650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BA893_RS04655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BA893_RS04660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BA893_RS04670	COG2204	response regulator
BA893_RS04695	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BA893_RS04700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BA893_RS04705	COG0776	regulation of translation
BA893_RS04710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA893_RS04715	COG1555	photosystem II stabilization
BA893_RS04730	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BA893_RS04735	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BA893_RS04740	COG0436	Aminotransferase
BA893_RS04745	COG1169	isochorismate synthase
BA893_RS04750	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BA893_RS04755	COG0596	Alpha beta hydrolase
BA893_RS04760	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BA893_RS04780	COG2855	membrane
BA893_RS04785	COG0477	Major facilitator Superfamily
BA893_RS04825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA893_RS04830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA893_RS04845	COG1522	sequence-specific DNA binding
BA893_RS04850	COG1946	Acyl-CoA thioesterase
BA893_RS04855	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BA893_RS04920	COG0110	maltose O-acetyltransferase activity
BA893_RS04925	COG1609	Transcriptional regulator
BA893_RS04930	COG0561	phosphatase activity
BA893_RS04935	COG1349	DNA-binding transcription factor activity
BA893_RS04965	COG1074	ATP-dependent DNA helicase activity
BA893_RS04980	COG1742	UPF0060 membrane protein
BA893_RS04985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BA893_RS04985	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BA893_RS05010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BA893_RS05025	COG0697	spore germination
BA893_RS05030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA893_RS05035	COG3344	reverse transcriptase
BA893_RS05045	COG3344	reverse transcriptase
BA893_RS05095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA893_RS05100	COG0519	Catalyzes the synthesis of GMP from XMP
BA893_RS05115	COG1279	arginine transmembrane transporter activity
BA893_RS05120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BA893_RS05125	COG1280	lysine exporter protein (LysE YggA)
BA893_RS05130	COG2076	Multidrug Resistance protein
BA893_RS05135	COG0583	DNA-binding transcription factor activity
BA893_RS05145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA893_RS05150	COG0174	glutamine synthetase
BA893_RS05155	COG0174	glutamine synthetase
BA893_RS05165	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BA893_RS05170	COG3842	ATPase activity
BA893_RS05175	COG1176	ABC-type spermidine putrescine transport system, permease component I
BA893_RS05180	COG1177	transmembrane transport
BA893_RS05190	COG1012	belongs to the aldehyde dehydrogenase family
BA893_RS05195	COG0519	Catalyzes the synthesis of GMP from XMP
BA893_RS05200	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BA893_RS05205	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BA893_RS05210	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BA893_RS05215	COG0517	IMP dehydrogenase activity
BA893_RS05215	COG0516	GMP reductase activity
BA893_RS05240	COG0537	adenosine 5'-monophosphoramidase activity
BA893_RS05265	COG3150	esterase
BA893_RS05270	COG1252	NADH dehydrogenase
BA893_RS05285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BA893_RS05295	COG4591	ABC-type transport system involved in lipoprotein release permease component
BA893_RS05300	COG1136	(ABC) transporter
BA893_RS05305	COG4591	ABC-type transport system involved in lipoprotein release permease component
BA893_RS05315	COG2333	competence protein COMEC
BA893_RS05315	COG0658	competence protein
BA893_RS05320	COG1132	(ABC) transporter
BA893_RS05335	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BA893_RS05340	COG2719	SpoVR family
BA893_RS05345	COG2718	Belongs to the UPF0229 family
BA893_RS05350	COG2766	serine protein kinase
BA893_RS05355	COG3013	Belongs to the UPF0304 family
BA893_RS05365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BA893_RS05375	COG1882	Formate acetyltransferase
BA893_RS05410	COG0708	Exodeoxyribonuclease III
BA893_RS05420	COG0583	DNA-binding transcription factor activity
BA893_RS05430	COG1346	cytolysis
BA893_RS05445	COG0730	response to heat
BA893_RS05450	COG1199	ATP-dependent helicase activity
BA893_RS05460	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BA893_RS05465	COG1187	pseudouridine synthase activity
BA893_RS05475	COG1278	Cold shock
BA893_RS05480	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BA893_RS05485	COG0542	response to heat
BA893_RS05490	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BA893_RS05495	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BA893_RS05500	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BA893_RS05510	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BA893_RS05520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BA893_RS05525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BA893_RS05530	COG0297	glycogen (starch) synthase activity
BA893_RS05550	COG3070	regulator of competence-specific genes
BA893_RS05555	COG1609	Transcriptional regulator
BA893_RS05560	COG3381	protein complex oligomerization
BA893_RS05565	COG0745	RESPONSE REGULATOR receiver
BA893_RS05570	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BA893_RS05575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BA893_RS05580	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
BA893_RS05585	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BA893_RS05590	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BA893_RS05620	COG4067	protein conserved in archaea
BA893_RS05620	COG0189	ligase activity
BA893_RS05625	COG0500	methyltransferase
BA893_RS05630	COG4106	trans-aconitate 2-methyltransferase activity
BA893_RS05635	COG1801	Protein of unknown function DUF72
BA893_RS05645	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BA893_RS05650	COG0632	four-way junction helicase activity
BA893_RS05655	COG2255	four-way junction helicase activity
BA893_RS05660	COG1271	oxidase subunit
BA893_RS05665	COG1294	oxidase, subunit
BA893_RS05670	COG4890	Cyd operon protein YbgT
BA893_RS05680	COG0824	Thioesterase
BA893_RS05685	COG0811	peptide transport
BA893_RS05700	COG0823	Involved in the tonB-independent uptake of proteins
BA893_RS05705	COG2885	chlorophyll binding
BA893_RS05710	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BA893_RS05715	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BA893_RS05725	COG3766	membrane
BA893_RS05735	COG0754	glutathionylspermidine amidase activity
BA893_RS05750	COG1858	cytochrome C peroxidase
BA893_RS05770	COG5002	protein histidine kinase activity
BA893_RS05770	COG0784	Response regulator, receiver
BA893_RS05785	COG0582	viral genome integration into host DNA
BA893_RS05795	COG0582	viral genome integration into host DNA
BA893_RS05825	COG1479	Protein of unknown function DUF262
BA893_RS05830	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BA893_RS05960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BA893_RS05965	COG1396	sequence-specific DNA binding
BA893_RS05970	COG3135	benzoate transporter
BA893_RS05975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA893_RS05980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BA893_RS06015	COG0686	Belongs to the AlaDH PNT family
BA893_RS06025	COG1674	ftsk spoiiie
BA893_RS06030	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BA893_RS06035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BA893_RS06045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BA893_RS06050	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BA893_RS06055	COG0156	8-amino-7-oxononanoate synthase activity
BA893_RS06065	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BA893_RS06070	COG0501	Belongs to the peptidase M48B family
BA893_RS06080	COG4221	oxidoreductase activity
BA893_RS06095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BA893_RS06115	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BA893_RS06125	COG0482	sulfurtransferase activity
BA893_RS06135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA893_RS06145	COG1757	Na H antiporter
BA893_RS06160	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BA893_RS06165	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BA893_RS06170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BA893_RS06175	COG0131	Imidazoleglycerol-phosphate dehydratase
BA893_RS06175	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BA893_RS06180	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BA893_RS06185	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BA893_RS06190	COG0107	imidazoleglycerol-phosphate synthase activity
BA893_RS06195	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BA893_RS06195	COG0140	phosphoribosyl-ATP diphosphatase activity
BA893_RS06200	COG3012	SEC-C Motif Domain Protein
BA893_RS06205	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BA893_RS06210	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BA893_RS06215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BA893_RS06220	COG0215	cysteine-tRNA ligase activity
BA893_RS06225	COG1435	thymidine kinase activity
BA893_RS06230	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BA893_RS06245	COG2116	formate transmembrane transporter activity
BA893_RS06250	COG0390	transport system, permease component
BA893_RS06255	COG4459	periplasmic nitrate reductase
BA893_RS06260	COG3005	denitrification pathway
BA893_RS06265	COG0243	molybdopterin cofactor binding
BA893_RS06280	COG1227	inorganic diphosphatase activity
BA893_RS06290	COG4172	Belongs to the ABC transporter superfamily
BA893_RS06315	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BA893_RS06320	COG1842	Phage shock protein A
BA893_RS06330	COG1983	PspC domain protein
BA893_RS06350	COG2818	Glycosylase
BA893_RS06355	COG0626	cystathionine gamma-synthase activity
BA893_RS06365	COG0733	neurotransmitter:sodium symporter activity
BA893_RS06370	COG0564	pseudouridine synthase activity
BA893_RS06380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BA893_RS06385	COG1151	hydroxylamine reductase activity
BA893_RS06390	COG3604	Transcriptional regulator
BA893_RS06400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BA893_RS06405	COG4136	ATPase activity
BA893_RS06410	COG4135	transport system, permease component
BA893_RS06415	COG4134	Bacterial extracellular solute-binding protein
BA893_RS06425	COG3313	Fe-S protein
BA893_RS06440	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BA893_RS06445	COG0642	Histidine kinase
BA893_RS06460	COG1061	Type III restriction enzyme res subunit
BA893_RS06465	COG1187	pseudouridine synthase activity
BA893_RS06470	COG2814	Major facilitator Superfamily
BA893_RS06500	COG3005	denitrification pathway
BA893_RS06505	COG0702	epimerase
BA893_RS06510	COG0534	Mate efflux family protein
BA893_RS06515	COG4181	ATPase activity
BA893_RS06530	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BA893_RS06540	COG1960	acyl-CoA dehydrogenase activity
BA893_RS06545	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BA893_RS06550	COG3273	potassium ion transport
BA893_RS06550	COG2985	domain, Protein
BA893_RS06555	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BA893_RS06565	COG1737	Transcriptional regulator
BA893_RS06570	COG0076	glutamate decarboxylase activity
BA893_RS06580	COG2431	L-lysine efflux transmembrane transporter activity
BA893_RS06590	COG3070	regulator of competence-specific genes
BA893_RS06605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA893_RS06605	COG4191	Histidine kinase
BA893_RS06615	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BA893_RS06625	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BA893_RS06630	COG4988	ABC transporter
BA893_RS06635	COG0492	ferredoxin-NADP+ reductase activity
BA893_RS06655	COG0471	metal ion transport
BA893_RS06660	COG2949	membrane
BA893_RS06665	COG0281	malic enzyme
BA893_RS06670	COG1643	Atp-dependent helicase
BA893_RS06685	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BA893_RS06720	COG0277	FAD linked oxidase domain protein
BA893_RS06720	COG0247	lactate metabolic process
BA893_RS06725	COG2020	methyltransferase activity
BA893_RS06730	COG0583	DNA-binding transcription factor activity
BA893_RS06735	COG3384	dioxygenase
BA893_RS06740	COG0435	Glutathione S-transferase
BA893_RS06750	COG0010	Belongs to the arginase family
BA893_RS06755	COG1228	amidohydrolase
BA893_RS06775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BA893_RS06785	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BA893_RS06800	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BA893_RS06805	COG0072	phenylalanine-tRNA ligase activity
BA893_RS06805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA893_RS06810	COG1621	beta-fructofuranosidase activity
BA893_RS06815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA893_RS06835	COG0776	regulation of translation
BA893_RS06845	COG0500	methyltransferase
BA893_RS06850	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BA893_RS06855	COG0295	cytidine deaminase activity
BA893_RS06860	COG1346	cytolysis
BA893_RS06865	COG1380	Effector of murein hydrolase LrgA
BA893_RS06870	COG2925	Exonuclease
BA893_RS06935	COG1484	DNA-dependent DNA replication
BA893_RS07125	COG2226	methyltransferase
BA893_RS07130	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BA893_RS07145	COG1823	symporter activity
BA893_RS07150	COG0702	epimerase
BA893_RS07155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BA893_RS07165	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BA893_RS07185	COG2988	succinylglutamate desuccinylase activity
BA893_RS07190	COG4139	cobalamin transport
BA893_RS07215	COG0583	DNA-binding transcription factor activity
BA893_RS07225	COG1451	nucleotide metabolic process
BA893_RS07230	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BA893_RS07285	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BA893_RS07290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA893_RS07305	COG2195	Cleaves the N-terminal amino acid of tripeptides
BA893_RS07315	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BA893_RS07325	COG0625	glutathione transferase activity
BA893_RS07350	COG4145	pantothenate transmembrane transporter activity
BA893_RS07355	COG3924	membrane
BA893_RS07375	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BA893_RS07385	COG1349	DNA-binding transcription factor activity
BA893_RS07390	COG0561	phosphatase activity
BA893_RS07405	COG0579	oxidoreductase
BA893_RS07435	COG4638	Rieske (2fe-2S)
BA893_RS07440	COG0583	DNA-binding transcription factor activity
BA893_RS07560	COG1953	Uracil, thiamine, allantoin
BA893_RS07575	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BA893_RS07590	COG2059	Chromate
BA893_RS07595	COG2059	Chromate
BA893_RS07625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BA893_RS07635	COG1414	Transcriptional regulator
BA893_RS07640	COG0400	carboxylic ester hydrolase activity
BA893_RS07650	COG0784	Response regulator, receiver
BA893_RS07650	COG5002	protein histidine kinase activity
BA893_RS07650	COG2198	Histidine kinase
BA893_RS07660	COG0559	Belongs to the binding-protein-dependent transport system permease family
BA893_RS07680	COG0829	nickel cation binding
BA893_RS07685	COG0831	urea catabolic process
BA893_RS07690	COG0832	Belongs to the urease beta subunit family
BA893_RS07695	COG0804	urea catabolic process
BA893_RS07705	COG0830	nickel cation binding
BA893_RS07710	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BA893_RS07725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA893_RS07725	COG4191	Histidine kinase
BA893_RS07745	COG0814	amino acid
BA893_RS07765	COG1132	(ABC) transporter
BA893_RS07770	COG1132	(ABC) transporter
BA893_RS07785	COG0443	Heat shock 70 kDa protein
BA893_RS07790	COG0443	Heat shock 70 kDa protein
BA893_RS07825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BA893_RS07830	COG1643	Atp-dependent helicase
BA893_RS07845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BA893_RS07855	COG1793	dna ligase
BA893_RS07865	COG0534	Mate efflux family protein
BA893_RS07870	COG0307	riboflavin synthase, alpha
BA893_RS07880	COG3001	Fructosamine kinase
BA893_RS07890	COG3706	GGDEF domain
BA893_RS07900	COG0791	NLP P60 protein
BA893_RS07905	COG0840	transmembrane signaling receptor activity
BA893_RS07920	COG3148	PFAM DTW domain containing protein
BA893_RS07925	COG1940	carbohydrate kinase activity
BA893_RS07940	COG0303	'Molybdopterin
BA893_RS07950	COG3842	ATPase activity
BA893_RS07965	COG2204	response regulator
BA893_RS07970	COG4191	Histidine kinase
BA893_RS07975	COG0488	(ABC) transporter
BA893_RS07980	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BA893_RS08010	COG3383	formate dehydrogenase (NAD+) activity
BA893_RS08010	COG0243	molybdopterin cofactor binding
BA893_RS08015	COG0437	4 iron, 4 sulfur cluster binding
BA893_RS08030	COG0110	maltose O-acetyltransferase activity
BA893_RS08035	COG2207	Transcriptional regulator
BA893_RS08040	COG0534	Mate efflux family protein
BA893_RS08045	COG0004	ammonium transporteR
BA893_RS08050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BA893_RS08055	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BA893_RS08065	COG1177	transmembrane transport
BA893_RS08075	COG3842	ATPase activity
BA893_RS08090	COG0037	tRNA processing
BA893_RS08095	COG0589	response to stress
BA893_RS08100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BA893_RS08115	COG2217	Heavy metal translocating P-type atpase
BA893_RS08125	COG2010	Cytochrome c
BA893_RS08140	COG3278	Belongs to the heme-copper respiratory oxidase family
BA893_RS08155	COG0784	Response regulator, receiver
BA893_RS08155	COG2205	protein histidine kinase activity
BA893_RS08160	COG2801	Transposase and inactivated derivatives
BA893_RS08170	COG0544	peptidyl-prolyl cis-trans isomerase activity
BA893_RS08205	COG3120	sequence-specific DNA binding
BA893_RS08210	COG1067	ATP-dependent peptidase activity
BA893_RS08215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BA893_RS08230	COG0488	(ABC) transporter
BA893_RS08240	COG0116	Belongs to the methyltransferase superfamily
BA893_RS08240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BA893_RS08250	COG0167	dihydroorotate dehydrogenase activity
BA893_RS08255	COG2902	Dehydrogenase
BA893_RS08260	COG0308	aminopeptidase N
BA893_RS08275	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BA893_RS08280	COG1956	GAF domain-containing protein
BA893_RS08285	COG1132	(ABC) transporter
BA893_RS08290	COG2995	paraquat-inducible protein a
BA893_RS08295	COG3008	intermembrane lipid transfer
BA893_RS08300	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BA893_RS08300	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BA893_RS08320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BA893_RS08325	COG1666	GTP binding
BA893_RS08340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA893_RS08345	COG4597	amino acid ABC transporter
BA893_RS08350	COG0765	amino acid transport
BA893_RS08355	COG1126	abc transporter atp-binding protein
BA893_RS08360	COG0670	Belongs to the BI1 family
BA893_RS08370	COG2920	part of a sulfur-relay system
BA893_RS08375	COG1254	Belongs to the acylphosphatase family
BA893_RS08380	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BA893_RS08395	COG2885	chlorophyll binding
BA893_RS08405	COG3706	GGDEF domain
BA893_RS08415	COG0602	queuosine metabolic process
BA893_RS08420	COG0561	phosphatase activity
BA893_RS08430	COG0110	maltose O-acetyltransferase activity
BA893_RS08470	COG1051	belongs to the nudix hydrolase family
BA893_RS08485	COG2828	Protein conserved in bacteria
BA893_RS08495	COG0372	Belongs to the citrate synthase family
BA893_RS08500	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BA893_RS08530	COG0730	response to heat
BA893_RS08535	COG2358	TRAP transporter, solute receptor (TAXI family
BA893_RS08540	COG1012	belongs to the aldehyde dehydrogenase family
BA893_RS08545	COG3284	Transcriptional regulator
BA893_RS08555	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BA893_RS08560	COG0363	glucosamine-6-phosphate deaminase activity
BA893_RS08565	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BA893_RS08575	COG4774	siderophore transport
BA893_RS08580	COG4565	transcriptional regulatory protein
BA893_RS08585	COG3290	protein histidine kinase activity
BA893_RS08600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA893_RS08615	COG0527	aspartate kinase activity
BA893_RS08625	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BA893_RS08630	COG0456	acetyltransferase
BA893_RS08640	COG4176	ABC-type proline glycine betaine transport system permease component
BA893_RS08645	COG2113	Glycine betaine
BA893_RS08665	COG4221	oxidoreductase activity
BA893_RS08675	COG0745	RESPONSE REGULATOR receiver
BA893_RS08680	COG0642	Histidine kinase
BA893_RS08685	COG1368	sulfuric ester hydrolase activity
BA893_RS08700	COG1404	Belongs to the peptidase S8 family
BA893_RS08720	COG1115	amino acid carrier protein
BA893_RS08735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BA893_RS08740	COG1280	lysine exporter protein (LysE YggA)
BA893_RS08745	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BA893_RS08750	COG3550	peptidyl-serine autophosphorylation
BA893_RS08775	COG2963	transposase activity
BA893_RS08800	COG3344	reverse transcriptase
BA893_RS08805	COG2801	Transposase and inactivated derivatives
BA893_RS08830	COG5001	Diguanylate cyclase
BA893_RS08830	COG3300	MHYT domain
BA893_RS08895	COG3706	GGDEF domain
BA893_RS08960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA893_RS08970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA893_RS08975	COG1742	UPF0060 membrane protein
BA893_RS08980	COG0668	transmembrane transport
BA893_RS09035	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BA893_RS09040	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BA893_RS09045	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BA893_RS09050	COG1289	transmembrane transporter activity
BA893_RS09065	COG1560	Kdo2-lipid A biosynthetic process
BA893_RS09075	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BA893_RS09080	COG3063	Type IV pilus biogenesis stability protein PilW
BA893_RS09110	COG2315	Protein conserved in bacteria
BA893_RS09115	COG1846	Transcriptional regulator
BA893_RS09120	COG0697	spore germination
BA893_RS09125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BA893_RS09130	COG1012	belongs to the aldehyde dehydrogenase family
BA893_RS09135	COG2957	Belongs to the agmatine deiminase family
BA893_RS09145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA893_RS09150	COG1012	belongs to the aldehyde dehydrogenase family
BA893_RS09155	COG1396	sequence-specific DNA binding
BA893_RS09155	COG1917	Cupin 2, conserved barrel domain protein
BA893_RS09160	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BA893_RS09165	COG0174	glutamine synthetase
BA893_RS09170	COG1757	Na H antiporter
BA893_RS09200	COG1126	abc transporter atp-binding protein
BA893_RS09205	COG0765	amino acid transport
BA893_RS09210	COG4597	amino acid ABC transporter
BA893_RS09215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA893_RS09220	COG0583	DNA-binding transcription factor activity
BA893_RS09230	COG2824	Alkylphosphonate utilization operon protein PhnA
BA893_RS09235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BA893_RS09270	COG0346	lactoylglutathione lyase activity
BA893_RS09295	COG1794	racemase activity, acting on amino acids and derivatives
BA893_RS09300	COG4977	sequence-specific DNA binding
BA893_RS09315	COG0724	RNA recognition motif
BA893_RS09340	COG0745	RESPONSE REGULATOR receiver
BA893_RS09345	COG5000	phosphorelay sensor kinase activity
BA893_RS09345	COG5002	protein histidine kinase activity
BA893_RS09370	COG1454	alcohol dehydrogenase
BA893_RS09375	COG2610	gluconate transmembrane transporter activity
BA893_RS09385	COG3718	enzyme involved in inositol metabolism
BA893_RS09390	COG0673	inositol 2-dehydrogenase activity
BA893_RS09395	COG2814	Major facilitator Superfamily
BA893_RS09395	COG0477	Major facilitator Superfamily
BA893_RS09400	COG1082	Xylose isomerase domain protein TIM barrel
BA893_RS09410	COG1082	Xylose isomerase domain protein TIM barrel
BA893_RS09420	COG1454	alcohol dehydrogenase
BA893_RS09420	COG1012	belongs to the aldehyde dehydrogenase family
BA893_RS09425	COG3962	Belongs to the TPP enzyme family
BA893_RS09430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BA893_RS09445	COG2999	glutathione oxidoreductase activity
BA893_RS09470	COG0477	Major facilitator Superfamily
BA893_RS09470	COG2814	Major facilitator Superfamily
BA893_RS09475	COG0673	inositol 2-dehydrogenase activity
BA893_RS09480	COG1082	Xylose isomerase domain protein TIM barrel
BA893_RS09500	COG2885	chlorophyll binding
BA893_RS09500	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BA893_RS09540	COG0438	transferase activity, transferring glycosyl groups
BA893_RS09565	COG3206	protein involved in exopolysaccharide biosynthesis
BA893_RS09565	COG0489	protein tyrosine kinase activity
BA893_RS09570	COG0438	transferase activity, transferring glycosyl groups
BA893_RS09580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BA893_RS09595	COG5492	domain, Protein
BA893_RS09640	COG0456	acetyltransferase
BA893_RS09645	COG2226	methyltransferase
BA893_RS09715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BA893_RS09725	COG3768	UPF0283 membrane protein
BA893_RS09730	COG3106	COG3106 Predicted ATPase
BA893_RS09755	COG0814	amino acid
BA893_RS09760	COG1760	l-serine dehydratase
BA893_RS09765	COG0720	synthase
BA893_RS09770	COG0017	Asparaginyl-tRNA synthetase
BA893_RS09780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BA893_RS09795	COG1448	Aminotransferase
BA893_RS09810	COG2176	DNA-directed DNA polymerase activity
BA893_RS09820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BA893_RS09825	COG1846	Transcriptional regulator
BA893_RS09850	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BA893_RS09865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA893_RS09870	COG3108	Peptidase M15
BA893_RS09875	COG2989	Protein conserved in bacteria
BA893_RS09900	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BA893_RS09910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BA893_RS09915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BA893_RS09930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BA893_RS09960	COG0019	diaminopimelate decarboxylase activity
BA893_RS10000	COG0322	excinuclease ABC activity
BA893_RS10005	COG2197	response regulator
BA893_RS10010	COG0417	DNA replication proofreading
BA893_RS10020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BA893_RS10025	COG3099	Belongs to the UPF0263 family
BA893_RS10030	COG1187	pseudouridine synthase activity
BA893_RS10040	COG0009	L-threonylcarbamoyladenylate synthase
BA893_RS10045	COG0613	PHP domain protein
BA893_RS10055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BA893_RS10060	COG0512	Glutamine amidotransferase of anthranilate synthase
BA893_RS10065	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BA893_RS10070	COG0134	indole-3-glycerol-phosphate synthase activity
BA893_RS10070	COG0135	phosphoribosylanthranilate isomerase activity
BA893_RS10075	COG0133	tryptophan synthase activity
BA893_RS10080	COG0159	tryptophan synthase activity
BA893_RS10085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BA893_RS10090	COG0318	PFAM AMP-dependent synthetase and ligase
BA893_RS10095	COG1301	dicarboxylic acid transport
BA893_RS10125	COG2350	Protein conserved in bacteria
BA893_RS10135	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BA893_RS10140	COG0583	DNA-binding transcription factor activity
BA893_RS10155	COG5001	Diguanylate cyclase
BA893_RS10160	COG1032	radical SAM domain protein
BA893_RS10165	COG0745	RESPONSE REGULATOR receiver
BA893_RS10170	COG3850	Histidine kinase
BA893_RS10170	COG5002	protein histidine kinase activity
BA893_RS10205	COG3118	belongs to the thioredoxin family
BA893_RS10210	COG4232	protein-disulfide reductase activity
BA893_RS10220	COG0189	ligase activity
BA893_RS10225	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BA893_RS10235	COG2308	Evidence 4 Homologs of previously reported genes of
BA893_RS10250	COG2307	Protein conserved in bacteria
BA893_RS10250	COG2308	Evidence 4 Homologs of previously reported genes of
BA893_RS10285	COG2863	cytochrome
BA893_RS10290	COG3258	Cytochrome c
BA893_RS10295	COG2995	paraquat-inducible protein a
BA893_RS10300	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BA893_RS10300	COG3008	intermembrane lipid transfer
BA893_RS10305	COG3009	Protein conserved in bacteria
BA893_RS10310	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BA893_RS10320	COG0463	Glycosyl transferase, family 2
BA893_RS10335	COG4166	transmembrane transport
BA893_RS10345	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BA893_RS10350	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BA893_RS10360	COG0539	negative regulation of cytoplasmic translation
BA893_RS10365	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BA893_RS10370	COG0616	signal peptide processing
BA893_RS10375	COG1028	Short-chain dehydrogenase reductase Sdr
BA893_RS10390	COG0587	DNA-directed DNA polymerase activity
BA893_RS10395	COG1940	carbohydrate kinase activity
BA893_RS10400	COG0469	pyruvate kinase activity
BA893_RS10405	COG4667	esterase of the alpha-beta hydrolase superfamily
BA893_RS10420	COG0733	neurotransmitter:sodium symporter activity
BA893_RS10430	COG1263	PTS System
BA893_RS10430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA893_RS10440	COG2190	(PTS) system
BA893_RS10440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BA893_RS10440	COG1263	PTS System
BA893_RS10445	COG0084	hydrolase, TatD family'
BA893_RS10450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BA893_RS10455	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BA893_RS10460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BA893_RS10490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BA893_RS10495	COG0416	fatty acid biosynthetic process
BA893_RS10505	COG1399	metal-binding, possibly nucleic acid-binding protein
BA893_RS10510	COG0424	maF-like protein
BA893_RS10515	COG0564	pseudouridine synthase activity
BA893_RS10520	COG1530	ribonuclease E activity
BA893_RS10525	COG0659	secondary active sulfate transmembrane transporter activity
BA893_RS10530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BA893_RS10535	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BA893_RS10545	COG0572	uridine kinase
BA893_RS10550	COG0489	protein tyrosine kinase activity
BA893_RS10555	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA893_RS10555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BA893_RS10565	COG2186	Transcriptional regulator
BA893_RS10570	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BA893_RS10575	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BA893_RS10580	COG0653	protein targeting
BA893_RS10585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BA893_RS10590	COG2199	diguanylate cyclase activity
BA893_RS10595	COG0366	Alpha amylase catalytic
BA893_RS10600	COG1122	ATPase activity
BA893_RS10605	COG4120	Belongs to the binding-protein-dependent transport system permease family
BA893_RS10615	COG3092	negative regulation of chromosome organization
BA893_RS10620	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BA893_RS10625	COG0857	belongs to the CobB CobQ family
BA893_RS10625	COG0280	phosphate acetyltransferase
BA893_RS10630	COG3174	membrane
BA893_RS10635	COG0435	Glutathione S-transferase
BA893_RS10645	COG0444	Belongs to the ABC transporter superfamily
BA893_RS10650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA893_RS10655	COG0601	transmembrane transport
BA893_RS10665	COG0314	molybdopterin synthase activity
BA893_RS10670	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BA893_RS10675	COG0315	cyclic pyranopterin monophosphate synthase activity
BA893_RS10680	COG0521	Mo-molybdopterin cofactor biosynthetic process
BA893_RS10685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BA893_RS10690	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BA893_RS10695	COG2198	Histidine kinase
BA893_RS10700	COG2204	response regulator
BA893_RS10705	COG0556	nucleotide-excision repair
BA893_RS10715	COG4657	Part of a membrane complex involved in electron transport
BA893_RS10720	COG2878	Part of a membrane complex involved in electron transport
BA893_RS10725	COG4656	Part of a membrane complex involved in electron transport
BA893_RS10730	COG4658	electron transport chain
BA893_RS10735	COG4659	FMN binding
BA893_RS10740	COG4660	Part of a membrane complex involved in electron transport
BA893_RS10745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BA893_RS10750	COG0346	lactoylglutathione lyase activity
BA893_RS10760	COG2885	chlorophyll binding
BA893_RS10765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BA893_RS10770	COG2056	Na+-H+ antiporter family
BA893_RS10850	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BA893_RS10900	COG4695	Portal protein
BA893_RS10970	COG4974	Belongs to the 'phage' integrase family
BA893_RS10975	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BA893_RS10990	COG1028	Short-chain dehydrogenase reductase Sdr
BA893_RS10995	COG1012	belongs to the aldehyde dehydrogenase family
BA893_RS10995	COG1454	alcohol dehydrogenase
BA893_RS11000	COG2095	MarC family integral membrane protein
BA893_RS11005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BA893_RS11010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BA893_RS11015	COG1757	Na H antiporter
BA893_RS11030	COG3081	Nucleoid-associated protein
BA893_RS11035	COG3082	Protein of unknown function (DUF1414)
BA893_RS11050	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BA893_RS11060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA893_RS11065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BA893_RS11070	COG1120	ATPase activity
BA893_RS11075	COG1522	sequence-specific DNA binding
BA893_RS11080	COG0626	cystathionine gamma-synthase activity
BA893_RS11085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA893_RS11090	COG0765	amino acid transport
BA893_RS11100	COG0123	including yeast histone deacetylase and acetoin utilization protein
BA893_RS11110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BA893_RS11115	COG0778	Nitroreductase
BA893_RS11120	COG0446	pyridine nucleotide-disulphide oxidoreductase
BA893_RS11120	COG1902	pentaerythritol trinitrate reductase activity
BA893_RS11125	COG0616	signal peptide processing
BA893_RS11130	COG0252	asparaginase activity
BA893_RS11135	COG3139	Protein of unknown function (DUF1315)
BA893_RS11145	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BA893_RS11150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BA893_RS11160	COG2226	methyltransferase
BA893_RS11175	COG1785	Belongs to the alkaline phosphatase family
BA893_RS11180	COG0668	transmembrane transport
BA893_RS11190	COG2261	transglycosylase associated protein
BA893_RS11200	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BA893_RS11205	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BA893_RS11220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BA893_RS11225	COG2832	Protein of unknown function (DUF454)
BA893_RS11230	COG0745	RESPONSE REGULATOR receiver
BA893_RS11235	COG0583	DNA-binding transcription factor activity
BA893_RS11240	COG5492	domain, Protein
BA893_RS11245	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BA893_RS11250	COG1286	toxin biosynthetic process
BA893_RS11255	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BA893_RS11260	COG0285	dihydrofolate synthase activity
BA893_RS11265	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BA893_RS11270	COG0101	tRNA pseudouridine synthase activity
BA893_RS11280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BA893_RS11285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BA893_RS11290	COG0747	negative chemotaxis
BA893_RS11295	COG1349	DNA-binding transcription factor activity
BA893_RS11305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BA893_RS11315	COG0431	NADPH-dependent FMN reductase
BA893_RS11325	COG3101	peptidyl-lysine hydroxylation
BA893_RS11330	COG2860	membrane
BA893_RS11335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BA893_RS11340	COG2890	protein-(glutamine-N5) methyltransferase activity
BA893_RS11345	COG2840	Smr protein MutS2
BA893_RS11350	COG2062	phosphohistidine phosphatase, SixA
BA893_RS11365	COG1024	Enoyl-CoA hydratase
BA893_RS11365	COG1250	3-hydroxyacyl-CoA dehydrogenase
BA893_RS11370	COG0183	Belongs to the thiolase family
BA893_RS11410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BA893_RS11415	COG1138	Cytochrome C-type biogenesis protein
BA893_RS11420	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BA893_RS11425	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BA893_RS11430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BA893_RS11435	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BA893_RS11440	COG4133	protoheme IX ABC transporter activity
BA893_RS11450	COG0835	chemotaxis
BA893_RS11460	COG1192	Involved in chromosome partitioning
BA893_RS11465	COG2201	protein-glutamate methylesterase activity
BA893_RS11470	COG0784	Response regulator, receiver
BA893_RS11470	COG0643	Histidine kinase
BA893_RS11470	COG2198	Histidine kinase
BA893_RS11475	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BA893_RS11515	COG1987	bacterial-type flagellum assembly
BA893_RS11565	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BA893_RS11575	COG1677	Flagellar hook-basal body complex protein FliE
BA893_RS11600	COG1516	flagellar protein fliS
BA893_RS11610	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BA893_RS11615	COG1334	flagellar protein FlaG
BA893_RS11620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BA893_RS11625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BA893_RS11630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BA893_RS11635	COG2837	iron assimilation
BA893_RS11660	COG1393	Belongs to the ArsC family
BA893_RS11665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BA893_RS11680	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BA893_RS11685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BA893_RS11690	COG2716	regulation of RNA biosynthetic process
BA893_RS11695	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BA893_RS11710	COG4783	chaperone-mediated protein folding
BA893_RS11715	COG1393	Belongs to the ArsC family
BA893_RS11735	COG2233	PERMEase
BA893_RS11740	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BA893_RS11745	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BA893_RS11750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BA893_RS11755	COG0121	glutamine amidotransferase
BA893_RS11760	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BA893_RS11765	COG1960	acyl-CoA dehydrogenase activity
BA893_RS11785	COG0328	RNA-DNA hybrid ribonuclease activity
BA893_RS11790	COG2226	methyltransferase
BA893_RS11795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BA893_RS11800	COG1388	LysM domain
BA893_RS11800	COG0741	lytic transglycosylase activity
BA893_RS11810	COG3021	interspecies interaction between organisms
BA893_RS11815	COG0347	Belongs to the P(II) protein family
BA893_RS11825	COG0037	tRNA processing
BA893_RS11830	COG0825	malonyl-CoA metabolic process
BA893_RS11835	COG0587	DNA-directed DNA polymerase activity
BA893_RS11845	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BA893_RS11850	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BA893_RS11860	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BA893_RS11865	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BA893_RS11875	COG0750	zinc metalloprotease
BA893_RS11880	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BA893_RS11885	COG0575	Belongs to the CDS family
BA893_RS11890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BA893_RS11895	COG0233	cytoplasmic translational termination
BA893_RS11900	COG0528	UMP kinase activity
BA893_RS11905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BA893_RS11910	COG0052	Belongs to the universal ribosomal protein uS2 family
BA893_RS11915	COG0024	Methionine aminopeptidase
BA893_RS11920	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BA893_RS11930	COG0564	pseudouridine synthase activity
BA893_RS11960	COG1671	Belongs to the UPF0178 family
BA893_RS11965	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BA893_RS11975	COG0254	rRNA binding
BA893_RS11980	COG1720	tRNA m6t6A37 methyltransferase activity
BA893_RS12000	COG0733	neurotransmitter:sodium symporter activity
BA893_RS12010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BA893_RS12015	COG0514	ATP-dependent DNA helicase (RecQ)
BA893_RS12020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BA893_RS12025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BA893_RS12045	COG0813	purine-nucleoside phosphorylase activity
BA893_RS12085	COG5002	protein histidine kinase activity
BA893_RS12105	COG2217	Heavy metal translocating P-type atpase
BA893_RS12190	COG3344	reverse transcriptase
BA893_RS12220	COG2991	Protein conserved in bacteria
BA893_RS12225	COG1477	protein flavinylation
BA893_RS12230	COG2871	sodium ion transport
BA893_RS12235	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BA893_RS12240	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BA893_RS12245	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BA893_RS12250	COG1805	sodium ion transport
BA893_RS12255	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BA893_RS12260	COG0271	Belongs to the BolA IbaG family
BA893_RS12265	COG2813	Specifically methylates the guanine in position
BA893_RS12290	COG1595	DNA-templated transcription, initiation
BA893_RS12310	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BA893_RS12315	COG0693	protein deglycase activity
BA893_RS12320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BA893_RS12325	COG3706	GGDEF domain
BA893_RS12330	COG2166	iron-sulfur cluster assembly
BA893_RS12335	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BA893_RS12340	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BA893_RS12350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BA893_RS12350	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BA893_RS12355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BA893_RS12360	COG1074	ATP-dependent DNA helicase activity
BA893_RS12365	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BA893_RS12385	COG3141	response to X-ray
BA893_RS12395	COG2171	N-acyltransferase activity
BA893_RS12400	COG0584	glycerophosphoryl diester phosphodiesterase
BA893_RS12405	COG2271	Major facilitator Superfamily
BA893_RS12410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BA893_RS12415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BA893_RS12420	COG1349	DNA-binding transcription factor activity
BA893_RS12425	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BA893_RS12450	COG1609	Transcriptional regulator
BA893_RS12455	COG1609	Transcriptional regulator
BA893_RS12460	COG0583	DNA-binding transcription factor activity
BA893_RS12535	COG4964	Belongs to the GSP D family
BA893_RS12565	COG2169	Transcriptional regulator
BA893_RS12570	COG1022	Amp-dependent synthetase and ligase
BA893_RS12575	COG0583	DNA-binding transcription factor activity
BA893_RS12580	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BA893_RS12585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BA893_RS12595	COG0560	Phosphoserine phosphatase
BA893_RS12605	COG0813	purine-nucleoside phosphorylase activity
BA893_RS12610	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BA893_RS12615	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BA893_RS12620	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BA893_RS12625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BA893_RS12630	COG0084	hydrolase, TatD family'
BA893_RS12640	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BA893_RS12655	COG3153	acetyltransferase
BA893_RS12660	COG3154	lipid carrier protein
BA893_RS12670	COG0826	peptidase U32
BA893_RS12675	COG0826	peptidase U32
BA893_RS12680	COG0534	Mate efflux family protein
BA893_RS12690	COG1185	polyribonucleotide nucleotidyltransferase activity
BA893_RS12695	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BA893_RS12700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BA893_RS12705	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BA893_RS12710	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BA893_RS12715	COG0195	Participates in both transcription termination and antitermination
BA893_RS12720	COG0779	Required for maturation of 30S ribosomal subunits
BA893_RS12735	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BA893_RS12745	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BA893_RS12750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BA893_RS12755	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BA893_RS12760	COG1534	Rna-binding protein
BA893_RS12765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BA893_RS12770	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BA893_RS12775	COG2027	D-alanyl-D-alanine carboxypeptidase
BA893_RS12785	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BA893_RS12790	COG0739	heme binding
BA893_RS12800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BA893_RS12805	COG0316	Belongs to the HesB IscA family
BA893_RS12810	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BA893_RS12815	COG0628	permease
BA893_RS12820	COG2813	Specifically methylates the guanine in position
BA893_RS12825	COG2205	protein histidine kinase activity
BA893_RS12825	COG0784	Response regulator, receiver
BA893_RS12830	COG0747	negative chemotaxis
BA893_RS12840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BA893_RS12845	COG0444	Belongs to the ABC transporter superfamily
BA893_RS12850	COG4608	Belongs to the ABC transporter superfamily
BA893_RS12860	COG2971	BadF BadG BcrA BcrD
BA893_RS12875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BA893_RS12880	COG3842	ATPase activity
BA893_RS12890	COG1840	ABC-type Fe3 transport system, periplasmic component
BA893_RS12895	COG0004	ammonium transporteR
BA893_RS12905	COG3112	Uncharacterised protein family (UPF0231)
BA893_RS12910	COG3835	regulator
BA893_RS12915	COG2610	gluconate transmembrane transporter activity
BA893_RS12920	COG1929	Belongs to the glycerate kinase type-1 family
BA893_RS12925	COG1049	propionate catabolic process, 2-methylcitrate cycle
BA893_RS12930	COG1752	Esterase of the alpha-beta hydrolase superfamily
BA893_RS12940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BA893_RS12945	COG1643	Atp-dependent helicase
BA893_RS12950	COG1489	DNA binding
BA893_RS12960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BA893_RS12970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BA893_RS12975	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BA893_RS12980	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BA893_RS12985	COG0842	Transport permease protein
BA893_RS12990	COG1131	(ABC) transporter
BA893_RS12995	COG0659	secondary active sulfate transmembrane transporter activity
BA893_RS13000	COG0288	reversible hydration of carbon dioxide
BA893_RS13015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BA893_RS13020	COG0508	dehydrogenase complex catalyzes the overall conversion of
BA893_RS13025	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BA893_RS13030	COG2186	Transcriptional regulator
BA893_RS13040	COG0157	Belongs to the NadC ModD family
BA893_RS13050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BA893_RS13055	COG1459	type II secretion system
BA893_RS13065	COG0237	dephospho-CoA kinase activity
BA893_RS13070	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BA893_RS13075	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BA893_RS13090	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BA893_RS13095	COG0228	four-way junction DNA binding
BA893_RS13100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BA893_RS13105	COG4137	Cytochrome C assembly protein
BA893_RS13110	COG4536	flavin adenine dinucleotide binding
BA893_RS13115	COG1854	S-ribosylhomocysteine lyase activity
BA893_RS13125	COG2918	glutathione biosynthetic process
BA893_RS13130	COG0612	Peptidase, M16
BA893_RS13135	COG1238	metal cluster binding
BA893_RS13145	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BA893_RS13150	COG0511	ligase activity, forming carbon-carbon bonds
BA893_RS13150	COG5016	pyruvate
BA893_RS13155	COG3630	sodium ion export across plasma membrane
BA893_RS13210	COG0527	aspartate kinase activity
BA893_RS13215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BA893_RS13230	COG1546	Belongs to the CinA family
BA893_RS13240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BA893_RS13250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BA893_RS13255	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BA893_RS13270	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BA893_RS13275	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BA893_RS13280	COG0148	phosphopyruvate hydratase activity
BA893_RS13285	COG0504	CTP synthase activity
BA893_RS13295	COG3956	TIGRFAM MazG family protein
BA893_RS13300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BA893_RS13305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BA893_RS13320	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BA893_RS13325	COG1381	Involved in DNA repair and RecF pathway recombination
BA893_RS13330	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BA893_RS13345	COG0481	GTPase activity
BA893_RS13350	COG3086	response to oxidative stress
BA893_RS13365	COG1595	DNA-templated transcription, initiation
BA893_RS13370	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BA893_RS13380	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BA893_RS13385	COG0354	folic acid binding
BA893_RS13400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BA893_RS13405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BA893_RS13410	COG3079	Belongs to the UPF0149 family
BA893_RS13415	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BA893_RS13425	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BA893_RS13430	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BA893_RS13435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BA893_RS13445	COG0583	DNA-binding transcription factor activity
BA893_RS13450	COG1279	arginine transmembrane transporter activity
BA893_RS13455	COG0668	transmembrane transport
BA893_RS13460	COG0191	fructose-bisphosphate aldolase activity
BA893_RS13465	COG0126	phosphoglycerate kinase activity
BA893_RS13470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BA893_RS13475	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BA893_RS13485	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BA893_RS13500	COG2356	endonuclease I
BA893_RS13505	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BA893_RS13510	COG0189	ligase activity
BA893_RS13515	COG1678	Uncharacterized ACR, COG1678
BA893_RS13520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BA893_RS13535	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BA893_RS13540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BA893_RS13545	COG0762	integral membrane protein
BA893_RS13560	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BA893_RS13565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BA893_RS13570	COG2066	Belongs to the glutaminase family
BA893_RS13590	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BA893_RS13595	COG0741	lytic transglycosylase activity
BA893_RS13705	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BA893_RS13710	COG0300	oxidoreductase activity
BA893_RS13725	COG1028	Short-chain dehydrogenase reductase Sdr
BA893_RS13740	COG0795	lipopolysaccharide-transporting ATPase activity
BA893_RS13745	COG0795	lipopolysaccharide-transporting ATPase activity
BA893_RS13750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BA893_RS13755	COG2927	DNA polymerase III (CHI subunit)
BA893_RS13760	COG0525	valine-tRNA ligase activity
BA893_RS13840	COG2235	arginine
BA893_RS13850	COG0540	Belongs to the ATCase OTCase family
BA893_RS13855	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BA893_RS13860	COG0251	oxidation-reduction process
BA893_RS13865	COG0204	Acyl-transferase
BA893_RS13870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BA893_RS13875	COG5007	Belongs to the BolA IbaG family
BA893_RS13885	COG2854	intermembrane phospholipid transfer
BA893_RS13890	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BA893_RS13895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BA893_RS13900	COG1127	ABC transporter
BA893_RS13910	COG0517	IMP dehydrogenase activity
BA893_RS13910	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BA893_RS13920	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BA893_RS13925	COG1137	ATPase activity
BA893_RS13935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BA893_RS13940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA893_RS13945	COG1660	Displays ATPase and GTPase activities
BA893_RS13950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BA893_RS13955	COG2239	Acts as a magnesium transporter
BA893_RS13960	COG0312	modulator of DNA gyrase
BA893_RS13965	COG3028	Belongs to the UPF0307 family
BA893_RS13970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BA893_RS13975	COG0564	pseudouridine synthase activity
BA893_RS13985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BA893_RS13990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BA893_RS13995	COG0312	modulator of DNA gyrase
BA893_RS14000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BA893_RS14005	COG3164	Protein of unknown function
BA893_RS14015	COG0424	maF-like protein
BA893_RS14020	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BA893_RS14025	COG1792	Involved in formation and maintenance of cell shape
BA893_RS14030	COG1077	Cell shape determining protein MreB Mrl
BA893_RS14075	COG1459	type II secretion system
BA893_RS14080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BA893_RS14090	COG3409	Peptidoglycan-binding domain 1 protein
BA893_RS14090	COG3267	Type II secretory pathway component ExeA
BA893_RS14115	COG2199	diguanylate cyclase activity
BA893_RS14115	COG2200	EAL domain
BA893_RS14120	COG0629	single-stranded DNA binding
BA893_RS14135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BA893_RS14145	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BA893_RS14150	COG0527	aspartate kinase activity
BA893_RS14155	COG0646	methionine synthase
BA893_RS14155	COG1410	methionine synthase
BA893_RS14170	COG3335	DDE superfamily endonuclease
BA893_RS14220	COG0175	sulfate reduction
BA893_RS14225	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BA893_RS14230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BA893_RS14250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BA893_RS14255	COG0735	belongs to the Fur family
BA893_RS14265	COG0166	Belongs to the GPI family
BA893_RS14270	COG0432	Pfam Uncharacterised protein family UPF0047
BA893_RS14275	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BA893_RS14310	COG2965	DNA replication, synthesis of RNA primer
BA893_RS14315	COG0360	Binds together with S18 to 16S ribosomal RNA
BA893_RS14320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BA893_RS14325	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BA893_RS14335	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BA893_RS14340	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BA893_RS14370	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BA893_RS14380	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BA893_RS14380	COG0678	peroxiredoxin activity
BA893_RS14385	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BA893_RS14385	COG0165	Argininosuccinate lyase
BA893_RS14390	COG0137	argininosuccinate synthase activity
BA893_RS14395	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BA893_RS14400	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BA893_RS14410	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BA893_RS14420	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BA893_RS14425	COG0460	homoserine dehydrogenase
BA893_RS14425	COG0527	aspartate kinase activity
BA893_RS14430	COG0626	cystathionine gamma-synthase activity
BA893_RS14440	COG0281	malic enzyme
BA893_RS14455	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BA893_RS14475	COG2923	Belongs to the DsrF TusC family
BA893_RS14480	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BA893_RS14485	COG2964	Protein conserved in bacteria
BA893_RS14490	COG0545	Peptidyl-prolyl cis-trans isomerase
BA893_RS14500	COG2900	Belongs to the SlyX family
BA893_RS14510	COG1047	Peptidyl-prolyl cis-trans
BA893_RS14525	COG2249	NAD(P)H dehydrogenase (quinone) activity
BA893_RS14530	COG0488	(ABC) transporter
BA893_RS14540	COG0429	hydrolase of the alpha beta-hydrolase fold
BA893_RS14545	COG3089	Belongs to the UPF0270 family
BA893_RS14550	COG3954	Phosphoribulokinase
BA893_RS14555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BA893_RS14565	COG1012	belongs to the aldehyde dehydrogenase family
BA893_RS14575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BA893_RS14580	COG0512	Glutamine amidotransferase of anthranilate synthase
BA893_RS14585	COG0180	Tryptophanyl-tRNA synthetase
BA893_RS14590	COG0546	phosphoglycolate phosphatase activity
BA893_RS14595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BA893_RS14600	COG0557	exoribonuclease II activity
BA893_RS14605	COG1959	2 iron, 2 sulfur cluster binding
BA893_RS14610	COG1017	nitric oxide dioxygenase activity
BA893_RS14610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BA893_RS14615	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BA893_RS14620	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BA893_RS14625	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BA893_RS14630	COG0330	HflC and HflK could
BA893_RS14635	COG0330	HflC and HflK could
BA893_RS14640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BA893_RS14650	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BA893_RS14655	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BA893_RS14660	COG0860	N-Acetylmuramoyl-L-alanine amidase
BA893_RS14665	COG0802	atpase or kinase
BA893_RS14670	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BA893_RS14735	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BA893_RS14740	COG1162	GTPase activity
BA893_RS14750	COG0471	metal ion transport
BA893_RS14760	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BA893_RS14765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BA893_RS14775	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BA893_RS14780	COG1045	serine acetyltransferase
BA893_RS14785	COG4942	peptidase
BA893_RS14805	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BA893_RS14810	COG1053	succinate dehydrogenase
BA893_RS14815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BA893_RS14835	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BA893_RS14840	COG1509	lysine 2,3-aminomutase activity
BA893_RS14845	COG1285	pathogenesis
BA893_RS14865	COG0534	Mate efflux family protein
BA893_RS14870	COG0205	6-phosphofructokinase activity
BA893_RS14880	COG3678	ATP-independent chaperone mediated protein folding
BA893_RS14885	COG0745	RESPONSE REGULATOR receiver
BA893_RS14890	COG2205	protein histidine kinase activity
BA893_RS14895	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BA893_RS14900	COG3030	protein affecting phage T7 exclusion by the F plasmid
BA893_RS14905	COG1027	Aspartate ammonia-lyase
BA893_RS14910	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BA893_RS14915	COG4232	protein-disulfide reductase activity
BA893_RS14925	COG3263	regulation of cellular component size
BA893_RS14935	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BA893_RS14950	COG2205	protein histidine kinase activity
BA893_RS14950	COG2198	Histidine kinase
BA893_RS14950	COG0784	Response regulator, receiver
BA893_RS14955	COG2814	Major facilitator Superfamily
BA893_RS14970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BA893_RS14975	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BA893_RS14980	COG0511	ligase activity, forming carbon-carbon bonds
BA893_RS14985	COG0439	Biotin carboxylase
BA893_RS14990	COG2264	protein methyltransferase activity
BA893_RS14995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BA893_RS15000	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BA893_RS15030	COG3335	DDE superfamily endonuclease
BA893_RS15080	COG3710	Transcriptional regulator
BA893_RS15095	COG0138	bifunctional purine biosynthesis protein purh
BA893_RS15100	COG0151	Belongs to the GarS family
BA893_RS15115	COG1253	flavin adenine dinucleotide binding
BA893_RS15120	COG3068	Protein conserved in bacteria
BA893_RS15130	COG1573	uracil-dna glycosylase
BA893_RS15135	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BA893_RS15140	COG2816	NAD+ diphosphatase activity
BA893_RS15145	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BA893_RS15150	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BA893_RS15155	COG0085	RNA polymerase activity
BA893_RS15160	COG0222	ribosome binding
BA893_RS15165	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BA893_RS15180	COG0250	Participates in transcription elongation, termination and antitermination
BA893_RS15185	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BA893_RS15225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BA893_RS15235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BA893_RS15320	COG4206	TonB-dependent receptor
BA893_RS15340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BA893_RS15345	COG0534	Mate efflux family protein
BA893_RS15350	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BA893_RS15355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BA893_RS15360	COG2937	Belongs to the GPAT DAPAT family
BA893_RS15365	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BA893_RS15370	COG3161	chorismate lyase activity
BA893_RS15375	COG1580	Controls the rotational direction of flagella during chemotaxis
BA893_RS15380	COG0705	Rhomboid family
BA893_RS15395	COG2177	Part of the ABC transporter FtsEX involved in
BA893_RS15400	COG2884	Cell division ATP-binding protein ftsE
BA893_RS15405	COG0552	protein localization to endoplasmic reticulum
BA893_RS15410	COG0742	ribosomal rna small subunit methyltransferase
BA893_RS15455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BA893_RS15460	COG0640	Transcriptional regulator
BA893_RS15465	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BA893_RS15470	COG1280	lysine exporter protein (LysE YggA)
BA893_RS15475	COG2267	carboxylic ester hydrolase activity
BA893_RS15480	COG0561	phosphatase activity
BA893_RS15495	COG3148	PFAM DTW domain containing protein
BA893_RS15500	COG1011	Hydrolase
BA893_RS15515	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BA893_RS15520	COG0019	diaminopimelate decarboxylase activity
BA893_RS15525	COG1965	Belongs to the frataxin family
BA893_RS15530	COG3072	Adenylate cyclase
BA893_RS15535	COG0181	hydroxymethylbilane synthase activity
BA893_RS15540	COG1587	Uroporphyrinogen-III synthase
BA893_RS15545	COG2959	enzyme of heme biosynthesis
BA893_RS15550	COG3071	HemY protein
BA893_RS15595	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BA893_RS15610	COG3118	belongs to the thioredoxin family
BA893_RS15615	COG0513	Belongs to the DEAD box helicase family
BA893_RS15620	COG0248	Ppx GppA phosphatase
BA893_RS15625	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BA893_RS15635	COG0514	ATP-dependent DNA helicase (RecQ)
BA893_RS15640	COG2962	Rard protein
BA893_RS15650	COG1280	lysine exporter protein (LysE YggA)
BA893_RS15655	COG0405	Gamma-glutamyltransferase
BA893_RS15660	COG0210	DNA helicase
BA893_RS15670	COG3220	belongs to the UPF0276 family
BA893_RS15700	COG0006	proline dipeptidase activity
BA893_RS15700	COG0006	proline dipeptidase activity
BA893_RS15710	COG2022	thiamine diphosphate biosynthetic process
BA893_RS15715	COG2104	thiamine diphosphate biosynthetic process
BA893_RS15720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BA893_RS15730	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BA893_RS15735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BA893_RS15740	COG2132	Multicopper oxidase
BA893_RS15790	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BA893_RS15800	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BA893_RS15805	COG0408	coproporphyrinogen oxidase activity
BA893_RS15810	COG0009	L-threonylcarbamoyladenylate synthase
BA893_RS15815	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BA893_RS15820	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BA893_RS15825	COG0551	DNA topoisomerase type I activity
BA893_RS15830	COG2922	Belongs to the Smg family
BA893_RS15835	COG0758	DNA mediated transformation
BA893_RS15855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BA893_RS15855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BA893_RS15860	COG0569	domain protein
BA893_RS15865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BA893_RS15875	COG1272	protein, Hemolysin III
BA893_RS15880	COG4326	sporulation control protein
BA893_RS15885	COG3084	Protein conserved in bacteria
BA893_RS15895	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BA893_RS15900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BA893_RS15905	COG0204	Acyl-transferase
BA893_RS15915	COG0606	chelatase, subunit chli
BA893_RS15925	COG3978	acetolactate synthase activity
BA893_RS15940	COG0583	DNA-binding transcription factor activity
BA893_RS15945	COG2814	Major facilitator Superfamily
BA893_RS15950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BA893_RS15955	COG0765	amino acid transport
BA893_RS15965	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BA893_RS15970	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BA893_RS15975	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BA893_RS15980	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BA893_RS15985	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BA893_RS16000	COG0356	it plays a direct role in the translocation of protons across the membrane
BA893_RS16010	COG1475	DNA binding
BA893_RS16015	COG1192	Involved in chromosome partitioning
BA893_RS16025	COG0445	tRNA wobble uridine modification
BA893_RS16030	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BA893_RS16040	COG0706	membrane insertase activity
BA893_RS16045	COG0594	ribonuclease P activity
BA893_RS16055	COG1126	abc transporter atp-binding protein
BA893_RS16745	COG5001	Diguanylate cyclase
BA893_RS16745	COG3300	MHYT domain
BA893_RS16900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BA893_RS17340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BA893_RS17425	COG0438	transferase activity, transferring glycosyl groups
BA893_RS17530	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BA893_RS17580	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BA893_RS18130	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BA893_RS18260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BA893_RS18420	COG0069	glutamate synthase activity
BA893_RS18420	COG0070	glutamate synthase
BA893_RS18420	COG0067	glutamate synthase
BA893_RS18800	COG0542	response to heat
BA893_RS18810	COG0542	response to heat
BA893_RS19105	COG0517	IMP dehydrogenase activity
BA893_RS19105	COG0516	GMP reductase activity
BA893_RS19445	COG0484	heat shock protein binding
BA893_RS19800	COG0495	leucyl-tRNA aminoacylation
BA893_RS19935	COG2608	mercury ion transmembrane transporter activity
BA893_RS19935	COG2217	Heavy metal translocating P-type atpase
BA893_RS20020	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BA893_RS20430	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BA893_RS20430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BA893_RS20580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BA893_RS20985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BA893_RS21050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BA893_RS21220	COG2718	Belongs to the UPF0229 family
BA893_RS21375	COG0542	response to heat
BA893_RS21475	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BA893_RS21490	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BA893_RS21580	COG1294	oxidase, subunit
BA893_RS21720	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BA893_RS21820	COG1404	Belongs to the peptidase S8 family
BA893_RS22000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BA893_RS22065	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BA893_RS22100	COG0215	cysteine-tRNA ligase activity
BA893_RS22295	COG1061	Type III restriction enzyme res subunit
BA893_RS23655	COG2204	response regulator
BA893_RS23715	COG0243	molybdopterin cofactor binding
BA893_RS23715	COG3383	formate dehydrogenase (NAD+) activity
BA893_RS23855	COG2801	Transposase and inactivated derivatives
BA893_RS23930	COG2902	Dehydrogenase
BA893_RS24425	COG1404	Belongs to the peptidase S8 family
BA893_RS24855	COG1012	belongs to the aldehyde dehydrogenase family
BA893_RS24870	COG0174	glutamine synthetase