locus-tag	class	description
PN96_RS00040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PN96_RS00050	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PN96_RS00090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PN96_RS00095	COG0250	Participates in transcription elongation, termination and antitermination
PN96_RS00110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PN96_RS00115	COG0222	ribosome binding
PN96_RS00120	COG0085	RNA polymerase activity
PN96_RS00125	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PN96_RS00130	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
PN96_RS00135	COG2816	NAD+ diphosphatase activity
PN96_RS00140	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PN96_RS00145	COG1573	uracil-dna glycosylase
PN96_RS00155	COG3068	Protein conserved in bacteria
PN96_RS00160	COG1253	flavin adenine dinucleotide binding
PN96_RS00175	COG0151	Belongs to the GarS family
PN96_RS00180	COG0138	bifunctional purine biosynthesis protein purh
PN96_RS00195	COG3710	Transcriptional regulator
PN96_RS00265	COG0646	methionine synthase
PN96_RS00265	COG1410	methionine synthase
PN96_RS00270	COG0527	aspartate kinase activity
PN96_RS00280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PN96_RS00290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PN96_RS00305	COG0629	single-stranded DNA binding
PN96_RS00310	COG2200	EAL domain
PN96_RS00310	COG2199	diguanylate cyclase activity
PN96_RS00335	COG3267	Type II secretory pathway component ExeA
PN96_RS00335	COG3409	Peptidoglycan-binding domain 1 protein
PN96_RS00345	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PN96_RS00350	COG1459	type II secretion system
PN96_RS00360	COG2165	general secretion pathway protein
PN96_RS00395	COG1077	Cell shape determining protein MreB Mrl
PN96_RS00400	COG1792	Involved in formation and maintenance of cell shape
PN96_RS00405	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PN96_RS00410	COG0424	maF-like protein
PN96_RS00420	COG3164	Protein of unknown function
PN96_RS00425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PN96_RS00430	COG0312	modulator of DNA gyrase
PN96_RS00435	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PN96_RS00440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PN96_RS00450	COG0564	pseudouridine synthase activity
PN96_RS00455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PN96_RS00460	COG3028	Belongs to the UPF0307 family
PN96_RS00465	COG0312	modulator of DNA gyrase
PN96_RS00470	COG2239	Acts as a magnesium transporter
PN96_RS00475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PN96_RS00480	COG1660	Displays ATPase and GTPase activities
PN96_RS00485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PN96_RS00490	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PN96_RS00500	COG1137	ATPase activity
PN96_RS00505	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PN96_RS00515	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PN96_RS00515	COG0517	IMP dehydrogenase activity
PN96_RS00525	COG1127	ABC transporter
PN96_RS00530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PN96_RS00535	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PN96_RS00540	COG2854	intermembrane phospholipid transfer
PN96_RS00550	COG5007	Belongs to the BolA IbaG family
PN96_RS00555	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PN96_RS00560	COG0204	Acyl-transferase
PN96_RS00565	COG0251	oxidation-reduction process
PN96_RS00570	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
PN96_RS00575	COG0540	Belongs to the ATCase OTCase family
PN96_RS00590	COG2235	arginine
PN96_RS00615	COG0525	valine-tRNA ligase activity
PN96_RS00620	COG2927	DNA polymerase III (CHI subunit)
PN96_RS00625	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PN96_RS00630	COG0795	lipopolysaccharide-transporting ATPase activity
PN96_RS00635	COG0795	lipopolysaccharide-transporting ATPase activity
PN96_RS00650	COG1028	Short-chain dehydrogenase reductase Sdr
PN96_RS00665	COG0300	oxidoreductase activity
PN96_RS00670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PN96_RS00785	COG0741	lytic transglycosylase activity
PN96_RS00790	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PN96_RS00810	COG2066	Belongs to the glutaminase family
PN96_RS00815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PN96_RS00820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PN96_RS00835	COG0762	integral membrane protein
PN96_RS00840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PN96_RS00845	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PN96_RS00860	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PN96_RS00865	COG1678	Uncharacterized ACR, COG1678
PN96_RS00875	COG0189	ligase activity
PN96_RS00880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PN96_RS00885	COG2356	endonuclease I
PN96_RS00900	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PN96_RS00910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PN96_RS00915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PN96_RS00920	COG0126	phosphoglycerate kinase activity
PN96_RS00925	COG0191	fructose-bisphosphate aldolase activity
PN96_RS00930	COG0668	transmembrane transport
PN96_RS00935	COG1279	arginine transmembrane transporter activity
PN96_RS00940	COG0583	DNA-binding transcription factor activity
PN96_RS00950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PN96_RS00955	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PN96_RS00960	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PN96_RS00970	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PN96_RS00975	COG3079	Belongs to the UPF0149 family
PN96_RS00980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PN96_RS00985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PN96_RS01000	COG0354	folic acid binding
PN96_RS01005	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PN96_RS01015	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PN96_RS01020	COG1595	DNA-templated transcription, initiation
PN96_RS01035	COG3086	response to oxidative stress
PN96_RS01040	COG0481	GTPase activity
PN96_RS01055	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PN96_RS01060	COG1381	Involved in DNA repair and RecF pathway recombination
PN96_RS01065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PN96_RS01070	COG0736	holo-[acyl-carrier-protein] synthase activity
PN96_RS01085	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PN96_RS01090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PN96_RS01095	COG3956	TIGRFAM MazG family protein
PN96_RS01100	COG0504	CTP synthase activity
PN96_RS01105	COG0148	phosphopyruvate hydratase activity
PN96_RS01110	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PN96_RS01115	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PN96_RS01130	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PN96_RS01135	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PN96_RS01145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PN96_RS01150	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PN96_RS01155	COG1546	Belongs to the CinA family
PN96_RS01170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PN96_RS01175	COG0527	aspartate kinase activity
PN96_RS01235	COG3630	sodium ion export across plasma membrane
PN96_RS01240	COG5016	pyruvate
PN96_RS01240	COG0511	ligase activity, forming carbon-carbon bonds
PN96_RS01245	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
PN96_RS01255	COG1238	metal cluster binding
PN96_RS01260	COG0612	Peptidase, M16
PN96_RS01265	COG2918	glutathione biosynthetic process
PN96_RS01275	COG1854	S-ribosylhomocysteine lyase activity
PN96_RS01280	COG4536	flavin adenine dinucleotide binding
PN96_RS01285	COG4137	Cytochrome C assembly protein
PN96_RS01290	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PN96_RS01295	COG0228	four-way junction DNA binding
PN96_RS01300	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PN96_RS01315	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PN96_RS01320	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
PN96_RS01325	COG0237	dephospho-CoA kinase activity
PN96_RS01335	COG1459	type II secretion system
PN96_RS01340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PN96_RS01350	COG0157	Belongs to the NadC ModD family
PN96_RS01360	COG2186	Transcriptional regulator
PN96_RS01365	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PN96_RS01370	COG0508	dehydrogenase complex catalyzes the overall conversion of
PN96_RS01375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PN96_RS01390	COG0288	reversible hydration of carbon dioxide
PN96_RS01395	COG0659	secondary active sulfate transmembrane transporter activity
PN96_RS01400	COG1131	(ABC) transporter
PN96_RS01405	COG0842	Transport permease protein
PN96_RS01410	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PN96_RS01415	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PN96_RS01420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PN96_RS01430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PN96_RS01440	COG1489	DNA binding
PN96_RS01445	COG1643	Atp-dependent helicase
PN96_RS01450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PN96_RS01455	COG1752	Esterase of the alpha-beta hydrolase superfamily
PN96_RS01460	COG1049	propionate catabolic process, 2-methylcitrate cycle
PN96_RS01465	COG1929	Belongs to the glycerate kinase type-1 family
PN96_RS01470	COG2610	gluconate transmembrane transporter activity
PN96_RS01475	COG3835	regulator
PN96_RS01480	COG3112	Uncharacterised protein family (UPF0231)
PN96_RS01490	COG0004	ammonium transporteR
PN96_RS01495	COG1840	ABC-type Fe3 transport system, periplasmic component
PN96_RS01505	COG3842	ATPase activity
PN96_RS01510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PN96_RS01525	COG2971	BadF BadG BcrA BcrD
PN96_RS01535	COG4608	Belongs to the ABC transporter superfamily
PN96_RS01540	COG0444	Belongs to the ABC transporter superfamily
PN96_RS01545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PN96_RS01555	COG0747	negative chemotaxis
PN96_RS01560	COG0784	Response regulator, receiver
PN96_RS01560	COG2205	protein histidine kinase activity
PN96_RS01570	COG2813	Specifically methylates the guanine in position
PN96_RS01575	COG0628	permease
PN96_RS01580	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PN96_RS01585	COG0316	Belongs to the HesB IscA family
PN96_RS01590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PN96_RS01600	COG0739	heme binding
PN96_RS01605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PN96_RS01615	COG2027	D-alanyl-D-alanine carboxypeptidase
PN96_RS01620	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PN96_RS01625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PN96_RS01630	COG1534	Rna-binding protein
PN96_RS01635	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PN96_RS01640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PN96_RS01645	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PN96_RS01655	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PN96_RS01670	COG0779	Required for maturation of 30S ribosomal subunits
PN96_RS01675	COG0195	Participates in both transcription termination and antitermination
PN96_RS01680	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PN96_RS01685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PN96_RS01690	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PN96_RS01695	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PN96_RS01700	COG1185	polyribonucleotide nucleotidyltransferase activity
PN96_RS01710	COG0534	Mate efflux family protein
PN96_RS01715	COG0826	peptidase U32
PN96_RS01720	COG0826	peptidase U32
PN96_RS01730	COG3154	lipid carrier protein
PN96_RS01735	COG3153	acetyltransferase
PN96_RS01750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PN96_RS01760	COG0084	hydrolase, TatD family'
PN96_RS01765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PN96_RS01770	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PN96_RS01775	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PN96_RS01780	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PN96_RS01785	COG0813	purine-nucleoside phosphorylase activity
PN96_RS01795	COG0560	Phosphoserine phosphatase
PN96_RS01805	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PN96_RS01810	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PN96_RS01815	COG0583	DNA-binding transcription factor activity
PN96_RS01825	COG1022	Amp-dependent synthetase and ligase
PN96_RS01830	COG2169	Transcriptional regulator
PN96_RS01850	COG4964	Belongs to the GSP D family
PN96_RS01900	COG0463	Glycosyl transferase, family 2
PN96_RS01935	COG0583	DNA-binding transcription factor activity
PN96_RS01940	COG1609	Transcriptional regulator
PN96_RS01945	COG1609	Transcriptional regulator
PN96_RS01970	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PN96_RS01975	COG1349	DNA-binding transcription factor activity
PN96_RS01980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PN96_RS01985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PN96_RS01990	COG2271	Major facilitator Superfamily
PN96_RS01995	COG0584	glycerophosphoryl diester phosphodiesterase
PN96_RS02000	COG2171	N-acyltransferase activity
PN96_RS02010	COG3141	response to X-ray
PN96_RS02030	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PN96_RS02040	COG1074	ATP-dependent DNA helicase activity
PN96_RS02045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PN96_RS02050	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PN96_RS02050	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PN96_RS02060	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
PN96_RS02065	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PN96_RS02070	COG2166	iron-sulfur cluster assembly
PN96_RS02080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PN96_RS02085	COG0693	protein deglycase activity
PN96_RS02090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PN96_RS02110	COG1595	DNA-templated transcription, initiation
PN96_RS02135	COG2813	Specifically methylates the guanine in position
PN96_RS02140	COG0271	Belongs to the BolA IbaG family
PN96_RS02145	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PN96_RS02150	COG1805	sodium ion transport
PN96_RS02155	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PN96_RS02160	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PN96_RS02165	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PN96_RS02170	COG2871	sodium ion transport
PN96_RS02175	COG1477	protein flavinylation
PN96_RS02180	COG2991	Protein conserved in bacteria
PN96_RS02190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PN96_RS02195	COG0514	ATP-dependent DNA helicase (RecQ)
PN96_RS02200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PN96_RS02210	COG0733	neurotransmitter:sodium symporter activity
PN96_RS02230	COG1720	tRNA m6t6A37 methyltransferase activity
PN96_RS02235	COG0254	rRNA binding
PN96_RS02245	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
PN96_RS02250	COG1671	Belongs to the UPF0178 family
PN96_RS02280	COG0564	pseudouridine synthase activity
PN96_RS02290	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PN96_RS02295	COG0024	Methionine aminopeptidase
PN96_RS02300	COG0052	Belongs to the universal ribosomal protein uS2 family
PN96_RS02305	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PN96_RS02310	COG0528	UMP kinase activity
PN96_RS02315	COG0233	cytoplasmic translational termination
PN96_RS02320	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PN96_RS02325	COG0575	Belongs to the CDS family
PN96_RS02330	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PN96_RS02335	COG0750	zinc metalloprotease
PN96_RS02345	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
PN96_RS02350	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PN96_RS02360	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PN96_RS02365	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PN96_RS02375	COG0587	DNA-directed DNA polymerase activity
PN96_RS02380	COG0825	malonyl-CoA metabolic process
PN96_RS02385	COG0037	tRNA processing
PN96_RS02395	COG0347	Belongs to the P(II) protein family
PN96_RS02400	COG3021	interspecies interaction between organisms
PN96_RS02410	COG0741	lytic transglycosylase activity
PN96_RS02410	COG1388	LysM domain
PN96_RS02415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PN96_RS02420	COG2226	methyltransferase
PN96_RS02425	COG0328	RNA-DNA hybrid ribonuclease activity
PN96_RS02445	COG1960	acyl-CoA dehydrogenase activity
PN96_RS02450	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PN96_RS02455	COG0121	glutamine amidotransferase
PN96_RS02460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PN96_RS02465	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PN96_RS02470	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PN96_RS02475	COG2233	PERMEase
PN96_RS02495	COG1393	Belongs to the ArsC family
PN96_RS02500	COG4783	chaperone-mediated protein folding
PN96_RS02515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PN96_RS02520	COG2716	regulation of RNA biosynthetic process
PN96_RS02525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PN96_RS02530	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PN96_RS02545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PN96_RS02550	COG1393	Belongs to the ArsC family
PN96_RS02575	COG2837	iron assimilation
PN96_RS02580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PN96_RS02585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PN96_RS02590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PN96_RS02595	COG1334	flagellar protein FlaG
PN96_RS02600	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PN96_RS02610	COG1516	flagellar protein fliS
PN96_RS02635	COG1677	Flagellar hook-basal body complex protein FliE
PN96_RS02645	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PN96_RS02695	COG1987	bacterial-type flagellum assembly
PN96_RS02735	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PN96_RS02740	COG0643	Histidine kinase
PN96_RS02740	COG0784	Response regulator, receiver
PN96_RS02740	COG2198	Histidine kinase
PN96_RS02745	COG2201	protein-glutamate methylesterase activity
PN96_RS02750	COG1192	Involved in chromosome partitioning
PN96_RS02760	COG0835	chemotaxis
PN96_RS02770	COG4133	protoheme IX ABC transporter activity
PN96_RS02775	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PN96_RS02780	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PN96_RS02785	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PN96_RS02790	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PN96_RS02795	COG1138	Cytochrome C-type biogenesis protein
PN96_RS02800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PN96_RS02820	COG2067	long-chain fatty acid transport protein
PN96_RS02845	COG0183	Belongs to the thiolase family
PN96_RS02850	COG1024	Enoyl-CoA hydratase
PN96_RS02850	COG1250	3-hydroxyacyl-CoA dehydrogenase
PN96_RS02865	COG2062	phosphohistidine phosphatase, SixA
PN96_RS02870	COG2840	Smr protein MutS2
PN96_RS02875	COG2890	protein-(glutamine-N5) methyltransferase activity
PN96_RS02880	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PN96_RS02885	COG2860	membrane
PN96_RS02890	COG3101	peptidyl-lysine hydroxylation
PN96_RS02905	COG0431	NADPH-dependent FMN reductase
PN96_RS02915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PN96_RS02935	COG1349	DNA-binding transcription factor activity
PN96_RS02945	COG0747	negative chemotaxis
PN96_RS02950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PN96_RS02955	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PN96_RS02965	COG0101	tRNA pseudouridine synthase activity
PN96_RS02970	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PN96_RS02975	COG0285	dihydrofolate synthase activity
PN96_RS02980	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
PN96_RS02985	COG1286	toxin biosynthetic process
PN96_RS02990	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PN96_RS02995	COG0583	DNA-binding transcription factor activity
PN96_RS03000	COG0745	RESPONSE REGULATOR receiver
PN96_RS03005	COG2832	Protein of unknown function (DUF454)
PN96_RS03010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PN96_RS03025	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PN96_RS03030	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PN96_RS03040	COG2261	transglycosylase associated protein
PN96_RS03050	COG0668	transmembrane transport
PN96_RS03055	COG1785	Belongs to the alkaline phosphatase family
PN96_RS03070	COG2226	methyltransferase
PN96_RS03080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PN96_RS03085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PN96_RS03095	COG3139	Protein of unknown function (DUF1315)
PN96_RS03100	COG0252	asparaginase activity
PN96_RS03105	COG0616	signal peptide processing
PN96_RS03110	COG0446	pyridine nucleotide-disulphide oxidoreductase
PN96_RS03110	COG1902	pentaerythritol trinitrate reductase activity
PN96_RS03115	COG0778	Nitroreductase
PN96_RS03120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PN96_RS03130	COG0123	including yeast histone deacetylase and acetoin utilization protein
PN96_RS03140	COG0765	amino acid transport
PN96_RS03145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PN96_RS03150	COG0626	cystathionine gamma-synthase activity
PN96_RS03155	COG1522	sequence-specific DNA binding
PN96_RS03160	COG1120	ATPase activity
PN96_RS03165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PN96_RS03170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PN96_RS03180	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
PN96_RS03195	COG3082	Protein of unknown function (DUF1414)
PN96_RS03200	COG3081	Nucleoid-associated protein
PN96_RS03215	COG1757	Na H antiporter
PN96_RS03220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PN96_RS03225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PN96_RS03230	COG2095	MarC family integral membrane protein
PN96_RS03235	COG1454	alcohol dehydrogenase
PN96_RS03235	COG1012	belongs to the aldehyde dehydrogenase family
PN96_RS03240	COG1028	Short-chain dehydrogenase reductase Sdr
PN96_RS03255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PN96_RS03265	COG2056	Na+-H+ antiporter family
PN96_RS03270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PN96_RS03275	COG2885	chlorophyll binding
PN96_RS03285	COG0346	lactoylglutathione lyase activity
PN96_RS03290	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PN96_RS03295	COG4660	Part of a membrane complex involved in electron transport
PN96_RS03300	COG4659	FMN binding
PN96_RS03305	COG4658	electron transport chain
PN96_RS03310	COG4656	Part of a membrane complex involved in electron transport
PN96_RS03315	COG2878	Part of a membrane complex involved in electron transport
PN96_RS03320	COG4657	Part of a membrane complex involved in electron transport
PN96_RS03330	COG0556	nucleotide-excision repair
PN96_RS03335	COG2204	response regulator
PN96_RS03340	COG2198	Histidine kinase
PN96_RS03345	COG0391	Required for morphogenesis under gluconeogenic growth conditions
PN96_RS03350	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PN96_RS03355	COG0521	Mo-molybdopterin cofactor biosynthetic process
PN96_RS03360	COG0315	cyclic pyranopterin monophosphate synthase activity
PN96_RS03365	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PN96_RS03370	COG0314	molybdopterin synthase activity
PN96_RS03385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PN96_RS03390	COG0444	Belongs to the ABC transporter superfamily
PN96_RS03400	COG0435	Glutathione S-transferase
PN96_RS03405	COG3174	membrane
PN96_RS03410	COG0857	belongs to the CobB CobQ family
PN96_RS03410	COG0280	phosphate acetyltransferase
PN96_RS03415	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PN96_RS03420	COG3092	negative regulation of chromosome organization
PN96_RS03430	COG4120	Belongs to the binding-protein-dependent transport system permease family
PN96_RS03435	COG1122	ATPase activity
PN96_RS03440	COG0366	Alpha amylase catalytic
PN96_RS03445	COG2199	diguanylate cyclase activity
PN96_RS03450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PN96_RS03455	COG0653	protein targeting
PN96_RS03460	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PN96_RS03465	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PN96_RS03470	COG2186	Transcriptional regulator
PN96_RS03480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PN96_RS03480	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PN96_RS03485	COG0489	protein tyrosine kinase activity
PN96_RS03490	COG0572	uridine kinase
PN96_RS03500	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
PN96_RS03505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PN96_RS03510	COG0659	secondary active sulfate transmembrane transporter activity
PN96_RS03515	COG1530	ribonuclease E activity
PN96_RS03520	COG0564	pseudouridine synthase activity
PN96_RS03525	COG0424	maF-like protein
PN96_RS03530	COG1399	metal-binding, possibly nucleic acid-binding protein
PN96_RS03540	COG0416	fatty acid biosynthetic process
PN96_RS03545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PN96_RS03575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PN96_RS03580	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PN96_RS03585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PN96_RS03590	COG0084	hydrolase, TatD family'
PN96_RS03595	COG2190	(PTS) system
PN96_RS03595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PN96_RS03595	COG1263	PTS System
PN96_RS03605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PN96_RS03605	COG1263	PTS System
PN96_RS03615	COG0733	neurotransmitter:sodium symporter activity
PN96_RS03625	COG4667	esterase of the alpha-beta hydrolase superfamily
PN96_RS03630	COG0469	pyruvate kinase activity
PN96_RS03635	COG1940	carbohydrate kinase activity
PN96_RS03640	COG0587	DNA-directed DNA polymerase activity
PN96_RS03655	COG1028	Short-chain dehydrogenase reductase Sdr
PN96_RS03660	COG0616	signal peptide processing
PN96_RS03665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PN96_RS03670	COG0539	negative regulation of cytoplasmic translation
PN96_RS03680	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
PN96_RS03685	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PN96_RS03695	COG4166	transmembrane transport
PN96_RS03710	COG0463	Glycosyl transferase, family 2
PN96_RS03720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PN96_RS03725	COG3009	Protein conserved in bacteria
PN96_RS03730	COG3008	intermembrane lipid transfer
PN96_RS03730	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PN96_RS03735	COG2995	paraquat-inducible protein a
PN96_RS03740	COG3258	Cytochrome c
PN96_RS03745	COG2863	cytochrome
PN96_RS03780	COG2308	Evidence 4 Homologs of previously reported genes of
PN96_RS03780	COG2307	Protein conserved in bacteria
PN96_RS03795	COG2308	Evidence 4 Homologs of previously reported genes of
PN96_RS03805	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PN96_RS03810	COG0189	ligase activity
PN96_RS03820	COG4232	protein-disulfide reductase activity
PN96_RS03825	COG3118	belongs to the thioredoxin family
PN96_RS03860	COG5002	protein histidine kinase activity
PN96_RS03860	COG3850	Histidine kinase
PN96_RS03865	COG0745	RESPONSE REGULATOR receiver
PN96_RS03870	COG1032	radical SAM domain protein
PN96_RS03875	COG5001	Diguanylate cyclase
PN96_RS03890	COG0583	DNA-binding transcription factor activity
PN96_RS03895	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PN96_RS03905	COG2350	Protein conserved in bacteria
PN96_RS03935	COG1301	dicarboxylic acid transport
PN96_RS03940	COG0318	PFAM AMP-dependent synthetase and ligase
PN96_RS03945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PN96_RS03950	COG0159	tryptophan synthase activity
PN96_RS03955	COG0133	tryptophan synthase activity
PN96_RS03960	COG0135	phosphoribosylanthranilate isomerase activity
PN96_RS03960	COG0134	indole-3-glycerol-phosphate synthase activity
PN96_RS03965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PN96_RS03970	COG0512	Glutamine amidotransferase of anthranilate synthase
PN96_RS03975	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PN96_RS03985	COG0613	PHP domain protein
PN96_RS03990	COG0009	L-threonylcarbamoyladenylate synthase
PN96_RS04000	COG1187	pseudouridine synthase activity
PN96_RS04005	COG3099	Belongs to the UPF0263 family
PN96_RS04010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PN96_RS04020	COG0417	DNA replication proofreading
PN96_RS04025	COG2197	response regulator
PN96_RS04030	COG0322	excinuclease ABC activity
PN96_RS04075	COG0019	diaminopimelate decarboxylase activity
PN96_RS04105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PN96_RS04120	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PN96_RS04130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PN96_RS04140	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PN96_RS04165	COG2989	Protein conserved in bacteria
PN96_RS04170	COG3108	Peptidase M15
PN96_RS04175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PN96_RS04190	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PN96_RS04215	COG1846	Transcriptional regulator
PN96_RS04220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PN96_RS04230	COG2176	DNA-directed DNA polymerase activity
PN96_RS04245	COG1448	Aminotransferase
PN96_RS04260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PN96_RS04270	COG0017	Asparaginyl-tRNA synthetase
PN96_RS04275	COG0720	synthase
PN96_RS04280	COG1760	l-serine dehydratase
PN96_RS04285	COG0814	amino acid
PN96_RS04310	COG3106	COG3106 Predicted ATPase
PN96_RS04315	COG3768	UPF0283 membrane protein
PN96_RS04325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PN96_RS04340	COG0582	viral genome integration into host DNA
PN96_RS04370	COG5532	Uncharacterized conserved protein (DUF2303)
PN96_RS04450	COG1403	HNH endonuclease
PN96_RS04495	COG4220	transposase activity
PN96_RS04600	COG2226	methyltransferase
PN96_RS04610	COG2732	(Barnase) inhibitor
PN96_RS04660	COG5492	domain, Protein
PN96_RS04675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PN96_RS04685	COG0297	glycogen (starch) synthase activity
PN96_RS04690	COG0489	protein tyrosine kinase activity
PN96_RS04690	COG3206	protein involved in exopolysaccharide biosynthesis
PN96_RS04755	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PN96_RS04755	COG2885	chlorophyll binding
PN96_RS04775	COG2999	glutathione oxidoreductase activity
PN96_RS04790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PN96_RS04795	COG3962	Belongs to the TPP enzyme family
PN96_RS04800	COG1454	alcohol dehydrogenase
PN96_RS04800	COG1012	belongs to the aldehyde dehydrogenase family
PN96_RS04810	COG1082	Xylose isomerase domain protein TIM barrel
PN96_RS04820	COG1082	Xylose isomerase domain protein TIM barrel
PN96_RS04825	COG2814	Major facilitator Superfamily
PN96_RS04825	COG0477	Major facilitator Superfamily
PN96_RS04830	COG0673	inositol 2-dehydrogenase activity
PN96_RS04835	COG3718	enzyme involved in inositol metabolism
PN96_RS04845	COG2610	gluconate transmembrane transporter activity
PN96_RS04850	COG1454	alcohol dehydrogenase
PN96_RS04875	COG5002	protein histidine kinase activity
PN96_RS04875	COG5000	phosphorelay sensor kinase activity
PN96_RS04880	COG0745	RESPONSE REGULATOR receiver
PN96_RS04905	COG0724	RNA recognition motif
PN96_RS04925	COG4977	sequence-specific DNA binding
PN96_RS04960	COG0346	lactoylglutathione lyase activity
PN96_RS04990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PN96_RS04995	COG2824	Alkylphosphonate utilization operon protein PhnA
PN96_RS05010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PN96_RS05015	COG4597	amino acid ABC transporter
PN96_RS05020	COG0765	amino acid transport
PN96_RS05025	COG1126	abc transporter atp-binding protein
PN96_RS05055	COG1757	Na H antiporter
PN96_RS05060	COG0174	glutamine synthetase
PN96_RS05065	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PN96_RS05070	COG1917	Cupin 2, conserved barrel domain protein
PN96_RS05070	COG1396	sequence-specific DNA binding
PN96_RS05075	COG1012	belongs to the aldehyde dehydrogenase family
PN96_RS05080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PN96_RS05090	COG2957	Belongs to the agmatine deiminase family
PN96_RS05095	COG1012	belongs to the aldehyde dehydrogenase family
PN96_RS05100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PN96_RS05110	COG1846	Transcriptional regulator
PN96_RS05115	COG2315	Protein conserved in bacteria
PN96_RS05145	COG3063	Type IV pilus biogenesis stability protein PilW
PN96_RS05150	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
PN96_RS05160	COG1560	Kdo2-lipid A biosynthetic process
PN96_RS05180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PN96_RS05185	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PN96_RS05190	COG1280	lysine exporter protein (LysE YggA)
PN96_RS05195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PN96_RS05210	COG1115	amino acid carrier protein
PN96_RS05225	COG1404	Belongs to the peptidase S8 family
PN96_RS05240	COG1368	sulfuric ester hydrolase activity
PN96_RS05245	COG0642	Histidine kinase
PN96_RS05250	COG0745	RESPONSE REGULATOR receiver
PN96_RS05260	COG4221	oxidoreductase activity
PN96_RS05280	COG2113	Glycine betaine
PN96_RS05285	COG4176	ABC-type proline glycine betaine transport system permease component
PN96_RS05295	COG0456	acetyltransferase
PN96_RS05300	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PN96_RS05310	COG0527	aspartate kinase activity
PN96_RS05325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PN96_RS05340	COG3290	protein histidine kinase activity
PN96_RS05345	COG4565	transcriptional regulatory protein
PN96_RS05350	COG4774	siderophore transport
PN96_RS05360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PN96_RS05365	COG0363	glucosamine-6-phosphate deaminase activity
PN96_RS05370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PN96_RS05380	COG3284	Transcriptional regulator
PN96_RS05385	COG1012	belongs to the aldehyde dehydrogenase family
PN96_RS05390	COG2358	TRAP transporter, solute receptor (TAXI family
PN96_RS05395	COG0730	response to heat
PN96_RS05425	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PN96_RS05430	COG0372	Belongs to the citrate synthase family
PN96_RS05440	COG2828	Protein conserved in bacteria
PN96_RS05455	COG1051	belongs to the nudix hydrolase family
PN96_RS05475	COG5001	Diguanylate cyclase
PN96_RS05500	COG0110	maltose O-acetyltransferase activity
PN96_RS05510	COG0561	phosphatase activity
PN96_RS05515	COG0602	queuosine metabolic process
PN96_RS05525	COG3706	GGDEF domain
PN96_RS05535	COG2885	chlorophyll binding
PN96_RS05550	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PN96_RS05555	COG1254	Belongs to the acylphosphatase family
PN96_RS05560	COG2920	part of a sulfur-relay system
PN96_RS05570	COG0670	Belongs to the BI1 family
PN96_RS05575	COG1126	abc transporter atp-binding protein
PN96_RS05580	COG0765	amino acid transport
PN96_RS05585	COG4597	amino acid ABC transporter
PN96_RS05590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PN96_RS05605	COG1666	GTP binding
PN96_RS05610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PN96_RS05630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PN96_RS05630	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
PN96_RS05635	COG3008	intermembrane lipid transfer
PN96_RS05640	COG2995	paraquat-inducible protein a
PN96_RS05645	COG1132	(ABC) transporter
PN96_RS05650	COG1956	GAF domain-containing protein
PN96_RS05655	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
PN96_RS05670	COG0308	aminopeptidase N
PN96_RS05680	COG2902	Dehydrogenase
PN96_RS05685	COG0167	dihydroorotate dehydrogenase activity
PN96_RS05695	COG0116	Belongs to the methyltransferase superfamily
PN96_RS05695	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PN96_RS05705	COG0488	(ABC) transporter
PN96_RS05720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PN96_RS05725	COG1067	ATP-dependent peptidase activity
PN96_RS05730	COG3120	sequence-specific DNA binding
PN96_RS05800	COG0784	Response regulator, receiver
PN96_RS05800	COG2205	protein histidine kinase activity
PN96_RS05815	COG3278	Belongs to the heme-copper respiratory oxidase family
PN96_RS05830	COG2010	Cytochrome c
PN96_RS05840	COG2217	Heavy metal translocating P-type atpase
PN96_RS05855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PN96_RS05860	COG0589	response to stress
PN96_RS05865	COG0037	tRNA processing
PN96_RS05880	COG3842	ATPase activity
PN96_RS05890	COG1177	transmembrane transport
PN96_RS05900	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PN96_RS05905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PN96_RS05910	COG0004	ammonium transporteR
PN96_RS05915	COG0534	Mate efflux family protein
PN96_RS05920	COG2207	Transcriptional regulator
PN96_RS05925	COG0110	maltose O-acetyltransferase activity
PN96_RS05940	COG0437	4 iron, 4 sulfur cluster binding
PN96_RS05945	COG3383	formate dehydrogenase (NAD+) activity
PN96_RS05945	COG0243	molybdopterin cofactor binding
PN96_RS05975	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PN96_RS05980	COG0488	(ABC) transporter
PN96_RS05985	COG4191	Histidine kinase
PN96_RS05990	COG2204	response regulator
PN96_RS06005	COG3842	ATPase activity
PN96_RS06015	COG0303	'Molybdopterin
PN96_RS06030	COG1940	carbohydrate kinase activity
PN96_RS06035	COG3148	PFAM DTW domain containing protein
PN96_RS06055	COG0840	transmembrane signaling receptor activity
PN96_RS06060	COG0791	NLP P60 protein
PN96_RS06070	COG3706	GGDEF domain
PN96_RS06080	COG3001	Fructosamine kinase
PN96_RS06090	COG0307	riboflavin synthase, alpha
PN96_RS06095	COG0534	Mate efflux family protein
PN96_RS06105	COG1793	dna ligase
PN96_RS06115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PN96_RS06130	COG1643	Atp-dependent helicase
PN96_RS06135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PN96_RS06170	COG0443	Heat shock 70 kDa protein
PN96_RS06175	COG0443	Heat shock 70 kDa protein
PN96_RS06190	COG1132	(ABC) transporter
PN96_RS06195	COG1132	(ABC) transporter
PN96_RS06215	COG0814	amino acid
PN96_RS06235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PN96_RS06235	COG4191	Histidine kinase
PN96_RS06240	COG0471	metal ion transport
PN96_RS06250	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PN96_RS06255	COG0830	nickel cation binding
PN96_RS06265	COG0804	urea catabolic process
PN96_RS06270	COG0832	Belongs to the urease beta subunit family
PN96_RS06275	COG0831	urea catabolic process
PN96_RS06280	COG0829	nickel cation binding
PN96_RS06300	COG0559	Belongs to the binding-protein-dependent transport system permease family
PN96_RS06310	COG2198	Histidine kinase
PN96_RS06310	COG5002	protein histidine kinase activity
PN96_RS06310	COG0784	Response regulator, receiver
PN96_RS06320	COG0400	carboxylic ester hydrolase activity
PN96_RS06330	COG1414	Transcriptional regulator
PN96_RS06340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PN96_RS06370	COG2059	Chromate
PN96_RS06375	COG2059	Chromate
PN96_RS06390	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PN96_RS06405	COG1953	Uracil, thiamine, allantoin
PN96_RS06520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PN96_RS06525	COG0583	DNA-binding transcription factor activity
PN96_RS06530	COG4638	Rieske (2fe-2S)
PN96_RS06560	COG0579	oxidoreductase
PN96_RS06575	COG0561	phosphatase activity
PN96_RS06580	COG1349	DNA-binding transcription factor activity
PN96_RS06590	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PN96_RS06610	COG3924	membrane
PN96_RS06615	COG4145	pantothenate transmembrane transporter activity
PN96_RS06620	COG4580	involved in the transport of maltose and maltodextrins
PN96_RS06625	COG2723	6-phospho-beta-galactosidase activity
PN96_RS06630	COG1263	PTS System
PN96_RS06630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PN96_RS06630	COG2190	(PTS) system
PN96_RS06635	COG1609	Transcriptional regulator
PN96_RS06655	COG1172	Belongs to the binding-protein-dependent transport system permease family
PN96_RS06660	COG1172	Belongs to the binding-protein-dependent transport system permease family
PN96_RS06665	COG1129	ABC transporter
PN96_RS06715	COG2814	Major facilitator Superfamily
PN96_RS06760	COG0625	glutathione transferase activity
PN96_RS06770	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PN96_RS06780	COG2195	Cleaves the N-terminal amino acid of tripeptides
PN96_RS06795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PN96_RS06800	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PN96_RS06860	COG1451	nucleotide metabolic process
PN96_RS06870	COG0583	DNA-binding transcription factor activity
PN96_RS06895	COG4139	cobalamin transport
PN96_RS06900	COG2988	succinylglutamate desuccinylase activity
PN96_RS06920	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PN96_RS06930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PN96_RS06935	COG0702	epimerase
PN96_RS06940	COG1823	symporter activity
PN96_RS06955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PN96_RS07115	COG1484	DNA-dependent DNA replication
PN96_RS07190	COG2925	Exonuclease
PN96_RS07195	COG1380	Effector of murein hydrolase LrgA
PN96_RS07200	COG1346	cytolysis
PN96_RS07205	COG0295	cytidine deaminase activity
PN96_RS07210	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PN96_RS07215	COG0500	methyltransferase
PN96_RS07225	COG0776	regulation of translation
PN96_RS07245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PN96_RS07250	COG1621	beta-fructofuranosidase activity
PN96_RS07255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PN96_RS07255	COG0072	phenylalanine-tRNA ligase activity
PN96_RS07260	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PN96_RS07275	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PN96_RS07285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PN96_RS07305	COG1228	amidohydrolase
PN96_RS07310	COG0010	Belongs to the arginase family
PN96_RS07320	COG0435	Glutathione S-transferase
PN96_RS07325	COG3384	dioxygenase
PN96_RS07330	COG0583	DNA-binding transcription factor activity
PN96_RS07335	COG2020	methyltransferase activity
PN96_RS07340	COG0277	FAD linked oxidase domain protein
PN96_RS07340	COG0247	lactate metabolic process
PN96_RS07375	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PN96_RS07390	COG1643	Atp-dependent helicase
PN96_RS07395	COG0281	malic enzyme
PN96_RS07400	COG2949	membrane
PN96_RS07405	COG0471	metal ion transport
PN96_RS07425	COG0492	ferredoxin-NADP+ reductase activity
PN96_RS07430	COG4988	ABC transporter
PN96_RS07435	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PN96_RS07445	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PN96_RS07455	COG4191	Histidine kinase
PN96_RS07455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PN96_RS07470	COG3070	regulator of competence-specific genes
PN96_RS07480	COG2431	L-lysine efflux transmembrane transporter activity
PN96_RS07490	COG0076	glutamate decarboxylase activity
PN96_RS07495	COG1737	Transcriptional regulator
PN96_RS07500	COG1454	alcohol dehydrogenase
PN96_RS07500	COG1012	belongs to the aldehyde dehydrogenase family
PN96_RS07505	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PN96_RS07510	COG3273	potassium ion transport
PN96_RS07510	COG2985	domain, Protein
PN96_RS07515	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PN96_RS07520	COG1960	acyl-CoA dehydrogenase activity
PN96_RS07530	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PN96_RS07545	COG4181	ATPase activity
PN96_RS07550	COG0534	Mate efflux family protein
PN96_RS07555	COG0702	epimerase
PN96_RS07560	COG3005	denitrification pathway
PN96_RS07590	COG2814	Major facilitator Superfamily
PN96_RS07595	COG1187	pseudouridine synthase activity
PN96_RS07600	COG1061	Type III restriction enzyme res subunit
PN96_RS07615	COG0642	Histidine kinase
PN96_RS07625	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PN96_RS07640	COG3313	Fe-S protein
PN96_RS07650	COG4134	Bacterial extracellular solute-binding protein
PN96_RS07655	COG4135	transport system, permease component
PN96_RS07660	COG4136	ATPase activity
PN96_RS07665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PN96_RS07675	COG3604	Transcriptional regulator
PN96_RS07680	COG1151	hydroxylamine reductase activity
PN96_RS07685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PN96_RS07695	COG0564	pseudouridine synthase activity
PN96_RS07700	COG0733	neurotransmitter:sodium symporter activity
PN96_RS07710	COG0626	cystathionine gamma-synthase activity
PN96_RS07715	COG2818	Glycosylase
PN96_RS07735	COG1983	PspC domain protein
PN96_RS07745	COG1842	Phage shock protein A
PN96_RS07750	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PN96_RS07775	COG4172	Belongs to the ABC transporter superfamily
PN96_RS07785	COG1227	inorganic diphosphatase activity
PN96_RS07800	COG0243	molybdopterin cofactor binding
PN96_RS07805	COG3005	denitrification pathway
PN96_RS07810	COG4459	periplasmic nitrate reductase
PN96_RS07815	COG0390	transport system, permease component
PN96_RS07820	COG2116	formate transmembrane transporter activity
PN96_RS07835	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PN96_RS07840	COG1435	thymidine kinase activity
PN96_RS07845	COG0215	cysteine-tRNA ligase activity
PN96_RS07850	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PN96_RS07855	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PN96_RS07860	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
PN96_RS07865	COG3012	SEC-C Motif Domain Protein
PN96_RS07870	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PN96_RS07870	COG0140	phosphoribosyl-ATP diphosphatase activity
PN96_RS07875	COG0107	imidazoleglycerol-phosphate synthase activity
PN96_RS07880	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PN96_RS07885	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PN96_RS07890	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PN96_RS07890	COG0131	Imidazoleglycerol-phosphate dehydratase
PN96_RS07895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PN96_RS07900	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PN96_RS07905	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PN96_RS07920	COG1757	Na H antiporter
PN96_RS07930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PN96_RS07940	COG0482	sulfurtransferase activity
PN96_RS07950	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PN96_RS07970	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PN96_RS07985	COG4221	oxidoreductase activity
PN96_RS07995	COG0501	Belongs to the peptidase M48B family
PN96_RS08000	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PN96_RS08010	COG0156	8-amino-7-oxononanoate synthase activity
PN96_RS08015	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PN96_RS08020	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PN96_RS08030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PN96_RS08035	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PN96_RS08040	COG1674	ftsk spoiiie
PN96_RS08050	COG0686	Belongs to the AlaDH PNT family
PN96_RS08085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PN96_RS08090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PN96_RS08095	COG3135	benzoate transporter
PN96_RS08100	COG1396	sequence-specific DNA binding
PN96_RS08105	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PN96_RS08120	COG3052	prosthetic group binding
PN96_RS08165	COG2205	protein histidine kinase activity
PN96_RS08165	COG0784	Response regulator, receiver
PN96_RS08185	COG1858	cytochrome C peroxidase
PN96_RS08200	COG0754	glutathionylspermidine amidase activity
PN96_RS08210	COG3766	membrane
PN96_RS08220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PN96_RS08225	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PN96_RS08230	COG2885	chlorophyll binding
PN96_RS08235	COG0823	Involved in the tonB-independent uptake of proteins
PN96_RS08250	COG0811	peptide transport
PN96_RS08255	COG0824	Thioesterase
PN96_RS08265	COG4890	Cyd operon protein YbgT
PN96_RS08270	COG1294	oxidase, subunit
PN96_RS08275	COG1271	oxidase subunit
PN96_RS08280	COG2255	four-way junction helicase activity
PN96_RS08285	COG0632	four-way junction helicase activity
PN96_RS08290	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PN96_RS08300	COG1801	Protein of unknown function DUF72
PN96_RS08305	COG4106	trans-aconitate 2-methyltransferase activity
PN96_RS08310	COG0500	methyltransferase
PN96_RS08315	COG0189	ligase activity
PN96_RS08315	COG4067	protein conserved in archaea
PN96_RS08345	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PN96_RS08350	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
PN96_RS08355	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
PN96_RS08360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PN96_RS08365	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PN96_RS08370	COG0745	RESPONSE REGULATOR receiver
PN96_RS08375	COG3381	protein complex oligomerization
PN96_RS08380	COG1609	Transcriptional regulator
PN96_RS08385	COG3070	regulator of competence-specific genes
PN96_RS08405	COG0297	glycogen (starch) synthase activity
PN96_RS08410	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PN96_RS08415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PN96_RS08425	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PN96_RS08435	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PN96_RS08440	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PN96_RS08445	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PN96_RS08450	COG0542	response to heat
PN96_RS08455	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PN96_RS08460	COG1278	Cold shock
PN96_RS08470	COG1187	pseudouridine synthase activity
PN96_RS08475	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
PN96_RS08485	COG1199	ATP-dependent helicase activity
PN96_RS08490	COG0730	response to heat
PN96_RS08495	COG3923	Primosomal replication protein n
PN96_RS08505	COG1346	cytolysis
PN96_RS08515	COG0583	DNA-binding transcription factor activity
PN96_RS08525	COG0708	Exodeoxyribonuclease III
PN96_RS08560	COG1882	Formate acetyltransferase
PN96_RS08570	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PN96_RS08585	COG2766	serine protein kinase
PN96_RS08590	COG2718	Belongs to the UPF0229 family
PN96_RS08595	COG2719	SpoVR family
PN96_RS08600	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PN96_RS08615	COG1132	(ABC) transporter
PN96_RS08620	COG2333	competence protein COMEC
PN96_RS08620	COG0658	competence protein
PN96_RS08630	COG4591	ABC-type transport system involved in lipoprotein release permease component
PN96_RS08635	COG1136	(ABC) transporter
PN96_RS08640	COG4591	ABC-type transport system involved in lipoprotein release permease component
PN96_RS08650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PN96_RS08665	COG1252	NADH dehydrogenase
PN96_RS08670	COG3150	esterase
PN96_RS08695	COG0537	adenosine 5'-monophosphoramidase activity
PN96_RS08720	COG0516	GMP reductase activity
PN96_RS08720	COG0517	IMP dehydrogenase activity
PN96_RS08725	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PN96_RS08730	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PN96_RS08735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PN96_RS08740	COG0519	Catalyzes the synthesis of GMP from XMP
PN96_RS08745	COG1012	belongs to the aldehyde dehydrogenase family
PN96_RS08755	COG1177	transmembrane transport
PN96_RS08760	COG1176	ABC-type spermidine putrescine transport system, permease component I
PN96_RS08765	COG3842	ATPase activity
PN96_RS08770	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PN96_RS08780	COG0174	glutamine synthetase
PN96_RS08785	COG0174	glutamine synthetase
PN96_RS08790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PN96_RS08800	COG0583	DNA-binding transcription factor activity
PN96_RS08840	COG5290	Psort location Cytoplasmic, score
PN96_RS08920	COG3126	Type III secretion system lipoprotein chaperone (YscW)
PN96_RS08925	COG1946	Acyl-CoA thioesterase
PN96_RS08930	COG1522	sequence-specific DNA binding
PN96_RS08945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PN96_RS08950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PN96_RS08990	COG0477	Major facilitator Superfamily
PN96_RS08995	COG2855	membrane
PN96_RS09015	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PN96_RS09020	COG0596	Alpha beta hydrolase
PN96_RS09025	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PN96_RS09030	COG1169	isochorismate synthase
PN96_RS09035	COG0436	Aminotransferase
PN96_RS09040	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
PN96_RS09045	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PN96_RS09060	COG1555	photosystem II stabilization
PN96_RS09065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PN96_RS09070	COG0776	regulation of translation
PN96_RS09075	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PN96_RS09080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PN96_RS09105	COG2204	response regulator
PN96_RS09115	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PN96_RS09120	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PN96_RS09125	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PN96_RS09130	COG3842	ATPase activity
PN96_RS09140	COG1175	transmembrane transport
PN96_RS09160	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PN96_RS09170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PN96_RS09175	COG0569	domain protein
PN96_RS09180	COG0513	Belongs to the DEAD box helicase family
PN96_RS09185	COG1253	flavin adenine dinucleotide binding
PN96_RS09190	COG4771	TonB-dependent receptor
PN96_RS09205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PN96_RS09205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PN96_RS09210	COG3433	isochorismatase activity
PN96_RS09210	COG1535	isochorismatase
PN96_RS09215	COG1021	2,3-dihydroxybenzoate-AMP ligase
PN96_RS09220	COG1169	isochorismate synthase
PN96_RS09230	COG1028	Short-chain dehydrogenase reductase Sdr
PN96_RS09240	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PN96_RS09245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PN96_RS09250	COG0583	DNA-binding transcription factor activity
PN96_RS09255	COG2951	lytic endotransglycosylase activity
PN96_RS09270	COG2894	cell division
PN96_RS09275	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PN96_RS09280	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PN96_RS09285	COG0318	PFAM AMP-dependent synthetase and ligase
PN96_RS09290	COG2267	carboxylic ester hydrolase activity
PN96_RS09305	COG1214	PFAM Peptidase M22, glycoprotease
PN96_RS09310	COG1199	ATP-dependent helicase activity
PN96_RS09315	COG0788	formyltetrahydrofolate deformylase activity
PN96_RS09330	COG3102	Protein conserved in bacteria
PN96_RS09335	COG0018	arginyl-trna synthetase
PN96_RS09355	COG1918	ferrous iron import across plasma membrane
PN96_RS09360	COG4977	sequence-specific DNA binding
PN96_RS09365	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PN96_RS09370	COG1121	(ABC) transporter
PN96_RS09375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PN96_RS09385	COG0045	succinate-CoA ligase (ADP-forming) activity
PN96_RS09390	COG0508	dehydrogenase complex catalyzes the overall conversion of
PN96_RS09395	COG0567	Dehydrogenase, E1 component
PN96_RS09405	COG1053	succinate dehydrogenase
PN96_RS09410	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PN96_RS09425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PN96_RS09435	COG0033	Phosphoglucomutase
PN96_RS09440	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
PN96_RS09445	COG0596	Alpha beta hydrolase
PN96_RS09465	COG0735	belongs to the Fur family
PN96_RS09470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PN96_RS09475	COG2190	(PTS) system
PN96_RS09475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PN96_RS09475	COG1263	PTS System
PN96_RS09480	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PN96_RS09485	COG1940	carbohydrate kinase activity
PN96_RS09485	COG1846	Transcriptional regulator
PN96_RS09490	COG4651	solute:proton antiporter activity
PN96_RS09490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PN96_RS09495	COG0367	asparagine synthase
PN96_RS09500	COG0250	Participates in transcription elongation, termination and antitermination
PN96_RS09505	COG3104	oligopeptide transport
PN96_RS09510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PN96_RS09520	COG0326	Molecular chaperone. Has ATPase activity
PN96_RS09525	COG3710	Transcriptional regulator
PN96_RS09545	COG0622	Phosphoesterase
PN96_RS09575	COG1090	epimerase
PN96_RS09580	COG0300	oxidoreductase activity
PN96_RS09590	COG3118	belongs to the thioredoxin family
PN96_RS09595	COG0330	HflC and HflK could
PN96_RS09615	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PN96_RS09620	COG3115	cell septum assembly
PN96_RS09625	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
PN96_RS09630	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PN96_RS09640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PN96_RS09645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PN96_RS09650	COG2190	(PTS) system
PN96_RS09660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PN96_RS09665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PN96_RS09675	COG1705	Flagellar rod assembly protein muramidase FlgJ
PN96_RS09675	COG3951	Flagellar rod assembly protein muramidase FlgJ
PN96_RS09680	COG1706	bacterial-type flagellum-dependent cell motility
PN96_RS09685	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PN96_RS09695	COG4787	bacterial-type flagellum-dependent cell motility
PN96_RS09700	COG1749	Flagellar hook protein flgE
PN96_RS09710	COG1558	bacterial-type flagellum-dependent cell motility
PN96_RS09715	COG1815	bacterial-type flagellum-dependent cell motility
PN96_RS09720	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PN96_RS09725	COG0784	Response regulator, receiver
PN96_RS09725	COG0835	chemotaxis
PN96_RS09780	COG2217	Heavy metal translocating P-type atpase
PN96_RS09780	COG2608	mercury ion transmembrane transporter activity
PN96_RS09810	COG2840	Smr protein MutS2
PN96_RS09815	COG1187	pseudouridine synthase activity
PN96_RS09820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PN96_RS09825	COG0737	Belongs to the 5'-nucleotidase family
PN96_RS09830	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PN96_RS09835	COG2912	Transglutaminase-like superfamily
PN96_RS09840	COG3094	Invasion gene expression up-regulator, SirB
PN96_RS09845	COG2890	protein-(glutamine-N5) methyltransferase activity
PN96_RS09855	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PN96_RS09860	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PN96_RS09865	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PN96_RS09870	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PN96_RS09880	COG0012	GTP binding
PN96_RS09995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PN96_RS10000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PN96_RS10005	COG1702	phosphate starvation-inducible protein PhoH
PN96_RS10015	COG4535	Mg2 and Co2 transporter CorC
PN96_RS10020	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PN96_RS10025	COG2888	peptidyl-tyrosine sulfation
PN96_RS10030	COG0495	leucyl-tRNA aminoacylation
PN96_RS10035	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
PN96_RS10040	COG1466	dna polymerase III delta subunit
PN96_RS10045	COG0799	negative regulation of ribosome biogenesis
PN96_RS10055	COG0768	penicillin binding
PN96_RS10060	COG0772	Belongs to the SEDS family
PN96_RS10065	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PN96_RS10070	COG1686	Belongs to the peptidase S11 family
PN96_RS10080	COG0321	lipoyl(octanoyl) transferase activity
PN96_RS10085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PN96_RS10090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PN96_RS10100	COG0366	Alpha amylase catalytic
PN96_RS10105	COG1263	PTS System
PN96_RS10105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PN96_RS10115	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PN96_RS10120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PN96_RS10125	COG2011	ABC-type metal ion transport system permease component
PN96_RS10130	COG1464	Belongs to the NlpA lipoprotein family
PN96_RS10135	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
PN96_RS10145	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PN96_RS10145	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PN96_RS10160	COG1611	Belongs to the LOG family
PN96_RS10165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PN96_RS10170	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PN96_RS10175	COG2363	Small membrane protein
PN96_RS10185	COG0583	DNA-binding transcription factor activity
PN96_RS10195	COG0301	tRNA thio-modification
PN96_RS10195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PN96_RS10200	COG2885	chlorophyll binding
PN96_RS10205	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PN96_RS10215	COG0142	geranyltranstransferase activity
PN96_RS10225	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PN96_RS10230	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PN96_RS10240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PN96_RS10255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PN96_RS10255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PN96_RS10260	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PN96_RS10265	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PN96_RS10270	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PN96_RS10280	COG1073	alpha beta
PN96_RS10285	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
PN96_RS10290	COG2252	PERMEase
PN96_RS10295	COG2195	Cleaves the N-terminal amino acid of tripeptides
PN96_RS10330	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PN96_RS10330	COG0047	phosphoribosylformylglycinamidine synthase activity
PN96_RS10335	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PN96_RS10345	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
PN96_RS10375	COG0484	heat shock protein binding
PN96_RS10385	COG1301	dicarboxylic acid transport
PN96_RS10390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PN96_RS10395	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PN96_RS10400	COG0497	DNA recombination
PN96_RS10405	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PN96_RS10410	COG2914	Belongs to the UPF0125 (RnfH) family
PN96_RS10415	COG2867	negative regulation of translational initiation
PN96_RS10420	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PN96_RS10465	COG3254	rhamnose metabolic process
PN96_RS10470	COG1070	Carbohydrate kinase
PN96_RS10475	COG4806	L-rhamnose isomerase
PN96_RS10480	COG0235	Class ii aldolase
PN96_RS10485	COG0583	DNA-binding transcription factor activity
PN96_RS10490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PN96_RS10490	COG3153	acetyltransferase
PN96_RS10510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PN96_RS10515	COG2873	o-acetylhomoserine
PN96_RS10525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PN96_RS10530	COG1115	amino acid carrier protein
PN96_RS10540	COG1473	amidohydrolase
PN96_RS10555	COG1584	GPR1 FUN34 yaaH family protein
PN96_RS10570	COG0519	Catalyzes the synthesis of GMP from XMP
PN96_RS10570	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PN96_RS10575	COG0516	GMP reductase activity
PN96_RS10575	COG0517	IMP dehydrogenase activity
PN96_RS10595	COG1160	GTP binding
PN96_RS10600	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PN96_RS10605	COG2976	Protein conserved in bacteria
PN96_RS10610	COG0124	histidyl-tRNA synthetase
PN96_RS10615	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PN96_RS10630	COG0105	UTP biosynthetic process
PN96_RS10635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PN96_RS10640	COG2975	iron-sulfur cluster assembly
PN96_RS10645	COG0633	Ferredoxin
PN96_RS10650	COG0443	Heat shock 70 kDa protein
PN96_RS10665	COG0822	iron-sulfur transferase activity
PN96_RS10670	COG1104	cysteine desulfurase activity
PN96_RS10680	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
PN96_RS10685	COG0483	inositol monophosphate 1-phosphatase activity
PN96_RS10690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PN96_RS10695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PN96_RS10700	COG1862	Preprotein translocase
PN96_RS10705	COG0343	queuine tRNA-ribosyltransferase activity
PN96_RS10710	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PN96_RS10720	COG0517	IMP dehydrogenase activity
PN96_RS10730	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PN96_RS10735	COG0583	DNA-binding transcription factor activity
PN96_RS10740	COG0450	alkyl hydroperoxide reductase
PN96_RS10745	COG3142	Participates in the control of copper homeostasis
PN96_RS10755	COG0704	Plays a role in the regulation of phosphate uptake
PN96_RS10760	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PN96_RS10765	COG0581	inorganic phosphate transmembrane transporter activity
PN96_RS10775	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PN96_RS10780	COG0248	Ppx GppA phosphatase
PN96_RS10790	COG5002	protein histidine kinase activity
PN96_RS10795	COG0745	RESPONSE REGULATOR receiver
PN96_RS10805	COG2974	May be involved in recombination
PN96_RS10810	COG0826	peptidase U32
PN96_RS10815	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PN96_RS10825	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
PN96_RS10885	COG1116	anion transmembrane transporter activity
PN96_RS10900	COG0542	response to heat
PN96_RS10910	COG0564	pseudouridine synthase activity
PN96_RS10915	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PN96_RS10920	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PN96_RS10925	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PN96_RS10930	COG0077	Prephenate dehydratase
PN96_RS10930	COG1605	Chorismate mutase
PN96_RS10935	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
PN96_RS10940	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
PN96_RS10950	COG0488	(ABC) transporter
PN96_RS10955	COG0739	heme binding
PN96_RS10960	COG0287	Prephenate dehydrogenase
PN96_RS10960	COG1605	Chorismate mutase
PN96_RS10965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PN96_RS10970	COG1472	Belongs to the glycosyl hydrolase 3 family
PN96_RS10975	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PN96_RS10995	COG1966	Carbon starvation protein
PN96_RS11000	COG3275	phosphorelay sensor kinase activity
PN96_RS11005	COG3279	Response regulator of the LytR AlgR family
PN96_RS11010	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PN96_RS11015	COG1047	Peptidyl-prolyl cis-trans
PN96_RS11020	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PN96_RS11025	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PN96_RS11030	COG0196	riboflavin kinase activity
PN96_RS11035	COG0728	peptidoglycan biosynthetic process
PN96_RS11040	COG0268	Binds directly to 16S ribosomal RNA
PN96_RS11045	COG0640	Transcriptional regulator
PN96_RS11050	COG0583	DNA-binding transcription factor activity
PN96_RS11055	COG1283	sodium-dependent phosphate transmembrane transporter activity
PN96_RS11065	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PN96_RS11070	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PN96_RS11075	COG0730	response to heat
PN96_RS11090	COG3066	DNA modification
PN96_RS11100	COG0667	Aldo Keto reductase
PN96_RS11110	COG3290	protein histidine kinase activity
PN96_RS11110	COG3829	transcription factor binding
PN96_RS11115	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PN96_RS11125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PN96_RS11130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PN96_RS11135	COG4974	Belongs to the 'phage' integrase family
PN96_RS11150	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PN96_RS11155	COG0513	Belongs to the DEAD box helicase family
PN96_RS11160	COG3022	response to hydroperoxide
PN96_RS11165	COG1115	amino acid carrier protein
PN96_RS11180	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PN96_RS11185	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PN96_RS11190	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
PN96_RS11195	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PN96_RS11200	COG0083	homoserine kinase activity
PN96_RS11215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PN96_RS11225	COG0745	RESPONSE REGULATOR receiver
PN96_RS11235	COG5002	protein histidine kinase activity
PN96_RS11235	COG2198	Histidine kinase
PN96_RS11235	COG0784	Response regulator, receiver
PN96_RS11240	COG1242	4 iron, 4 sulfur cluster binding
PN96_RS11245	COG0070	glutamate synthase
PN96_RS11245	COG0067	glutamate synthase
PN96_RS11245	COG0069	glutamate synthase activity
PN96_RS11255	COG0070	glutamate synthase
PN96_RS11255	COG0069	glutamate synthase activity
PN96_RS11255	COG0067	glutamate synthase
PN96_RS11260	COG0493	'glutamate synthase
PN96_RS11270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PN96_RS11280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PN96_RS11285	COG2860	membrane
PN96_RS11290	COG0583	DNA-binding transcription factor activity
PN96_RS11295	COG0730	response to heat
PN96_RS11300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PN96_RS11305	COG0505	Belongs to the CarA family
PN96_RS11315	COG0494	nUDIX hydrolase
PN96_RS11320	COG0653	protein targeting
PN96_RS11330	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PN96_RS11335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PN96_RS11340	COG0849	cell division
PN96_RS11345	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PN96_RS11350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PN96_RS11355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PN96_RS11360	COG0772	Belongs to the SEDS family
PN96_RS11365	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PN96_RS11370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PN96_RS11375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PN96_RS11380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PN96_RS11385	COG0768	penicillin binding
PN96_RS11390	COG3116	cell division
PN96_RS11395	COG0275	rRNA processing
PN96_RS11405	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PN96_RS11420	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PN96_RS11425	COG2823	Periplasmic or secreted lipoprotein
PN96_RS11430	COG2969	positive regulation of protein catabolic process
PN96_RS11435	COG0625	glutathione transferase activity
PN96_RS11440	COG2857	Cytochrome c1
PN96_RS11445	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PN96_RS11450	COG0723	plastoquinol--plastocyanin reductase activity
PN96_RS11455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PN96_RS11460	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PN96_RS11465	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PN96_RS11470	COG3105	Protein conserved in bacteria
PN96_RS11480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PN96_RS11485	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PN96_RS11495	COG3150	esterase
PN96_RS11505	COG3151	Protein conserved in bacteria
PN96_RS11510	COG0494	nUDIX hydrolase
PN96_RS11515	COG1538	Outer membrane efflux protein
PN96_RS11525	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PN96_RS11540	COG3025	triphosphatase activity
PN96_RS11545	COG1392	Phosphate transport regulator
PN96_RS11550	COG0306	phosphate transporter
PN96_RS11555	COG4991	sh3 domain protein
PN96_RS11565	COG3409	Peptidoglycan-binding domain 1 protein
PN96_RS11565	COG3267	Type II secretory pathway component ExeA
PN96_RS11570	COG0617	tRNA 3'-terminal CCA addition
PN96_RS11575	COG1968	undecaprenyl-diphosphatase activity
PN96_RS11580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PN96_RS11585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PN96_RS11590	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PN96_RS11595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PN96_RS11600	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PN96_RS11605	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PN96_RS11610	COG1610	YqeY-like protein
PN96_RS11615	COG0358	DNA primase activity
PN96_RS11630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PN96_RS11670	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PN96_RS11670	COG2213	PTS system mannitol-specific
PN96_RS11675	COG0246	Mannitol dehydrogenase
PN96_RS11680	COG3722	fumarate hydratase activity
PN96_RS11685	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PN96_RS11690	COG1263	PTS System
PN96_RS11690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PN96_RS11700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PN96_RS11705	COG1349	DNA-binding transcription factor activity
PN96_RS11710	COG0469	pyruvate kinase activity
PN96_RS11715	COG0440	acetolactate synthase activity
PN96_RS11720	COG0028	Belongs to the TPP enzyme family
PN96_RS11725	COG1022	Amp-dependent synthetase and ligase
PN96_RS11730	COG0583	DNA-binding transcription factor activity
PN96_RS11740	COG0671	phosphoesterase, PA-phosphatase related
PN96_RS11755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PN96_RS11760	COG0473	3-isopropylmalate dehydrogenase activity
PN96_RS11770	COG0066	3-isopropylmalate dehydratase activity
PN96_RS11780	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PN96_RS11785	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PN96_RS11790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PN96_RS11795	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PN96_RS11800	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PN96_RS11805	COG2967	ApaG domain
PN96_RS11815	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PN96_RS11825	COG2966	Psort location CytoplasmicMembrane, score
PN96_RS11830	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PN96_RS11840	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PN96_RS11845	COG0142	geranyltranstransferase activity
PN96_RS11855	COG0039	L-malate dehydrogenase activity
PN96_RS11880	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
PN96_RS11885	COG1178	ABC-type Fe3 transport system permease component
PN96_RS11895	COG0163	prenyltransferase activity
PN96_RS11900	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PN96_RS11905	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PN96_RS11910	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PN96_RS11915	COG2105	PFAM AIG2 family protein
PN96_RS11920	COG2911	Protein conserved in bacteria
PN96_RS11930	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PN96_RS11940	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
PN96_RS11955	COG1136	(ABC) transporter
PN96_RS11975	COG0529	Catalyzes the synthesis of activated sulfate
PN96_RS11980	COG3273	potassium ion transport
PN96_RS11980	COG0471	metal ion transport
PN96_RS11985	COG2895	sulfate adenylyltransferase (ATP) activity
PN96_RS11990	COG0175	sulfate reduction
PN96_RS11995	COG1648	precorrin-2 dehydrogenase activity
PN96_RS11995	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PN96_RS12000	COG0737	Belongs to the 5'-nucleotidase family
PN96_RS12010	COG0513	Belongs to the DEAD box helicase family
PN96_RS12015	COG2153	protein acetylation
PN96_RS12025	COG0545	Peptidyl-prolyl cis-trans isomerase
PN96_RS12035	COG0203	ribosomal protein L17
PN96_RS12040	COG0202	RNA polymerase activity
PN96_RS12050	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PN96_RS12055	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PN96_RS12060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PN96_RS12065	COG0201	protein transport
PN96_RS12070	COG0200	Binds to the 23S rRNA
PN96_RS12075	COG1841	ribosomal large subunit assembly
PN96_RS12090	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PN96_RS12105	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PN96_RS12110	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PN96_RS12120	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PN96_RS12125	COG0255	Belongs to the universal ribosomal protein uL29 family
PN96_RS12135	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PN96_RS12140	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PN96_RS12145	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PN96_RS12150	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PN96_RS12160	COG0088	Forms part of the polypeptide exit tunnel
PN96_RS12165	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PN96_RS12175	COG0254	rRNA binding
PN96_RS12180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PN96_RS12185	COG1609	Transcriptional regulator
PN96_RS12200	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PN96_RS12205	COG1575	Belongs to the MenA family. Type 1 subfamily
PN96_RS12210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PN96_RS12220	COG1494	fructose-1,6-bisphosphatase
PN96_RS12235	COG3152	Membrane
PN96_RS12250	COG0149	triose-phosphate isomerase activity
PN96_RS12260	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PN96_RS12270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PN96_RS12280	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PN96_RS12290	COG0438	transferase activity, transferring glycosyl groups
PN96_RS12290	COG0297	glycogen (starch) synthase activity
PN96_RS12300	COG0438	transferase activity, transferring glycosyl groups
PN96_RS12330	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PN96_RS12335	COG3206	protein involved in exopolysaccharide biosynthesis
PN96_RS12335	COG0489	protein tyrosine kinase activity
PN96_RS12365	COG1682	transport, permease protein
PN96_RS12395	COG1091	dTDP-4-dehydrorhamnose reductase activity
PN96_RS12470	COG0471	metal ion transport
PN96_RS12470	COG3273	potassium ion transport
PN96_RS12475	COG0175	sulfate reduction
PN96_RS12480	COG0529	Catalyzes the synthesis of activated sulfate
PN96_RS12490	COG2895	sulfate adenylyltransferase (ATP) activity
PN96_RS12495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PN96_RS12515	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PN96_RS12525	COG1560	Kdo2-lipid A biosynthetic process
PN96_RS12530	COG0859	PFAM glycosyl transferase family 9
PN96_RS12535	COG1519	Transferase
PN96_RS12550	COG0562	UDP-galactopyranose mutase
PN96_RS12555	COG3642	lipopolysaccharide core region biosynthetic process
PN96_RS12560	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PN96_RS12565	COG0438	transferase activity, transferring glycosyl groups
PN96_RS12575	COG0859	PFAM glycosyl transferase family 9
PN96_RS12580	COG0438	transferase activity, transferring glycosyl groups
PN96_RS12585	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PN96_RS12590	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PN96_RS12610	COG2003	Belongs to the UPF0758 family
PN96_RS12615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PN96_RS12620	COG1309	transcriptional regulator
PN96_RS12625	COG1560	Kdo2-lipid A biosynthetic process
PN96_RS12630	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PN96_RS12635	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PN96_RS12645	COG1561	YicC-like family, N-terminal region
PN96_RS12670	COG4608	Belongs to the ABC transporter superfamily
PN96_RS12675	COG0444	Belongs to the ABC transporter superfamily
PN96_RS12680	COG0747	negative chemotaxis
PN96_RS12685	COG4239	(ABC) transporter, permease
PN96_RS12690	COG4174	ABC transporter (Permease)
PN96_RS12710	COG0811	peptide transport
PN96_RS12715	COG0848	biopolymer transport protein
PN96_RS12730	COG0194	GDP metabolic process
PN96_RS12735	COG1758	RNA polymerase activity
PN96_RS12740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PN96_RS12745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PN96_RS12750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PN96_RS12755	COG2233	PERMEase
PN96_RS12775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PN96_RS12785	COG2183	response to ionizing radiation
PN96_RS12795	COG0596	Alpha beta hydrolase
PN96_RS12800	COG1040	competence protein
PN96_RS12810	COG0494	nUDIX hydrolase
PN96_RS12815	COG1218	3'(2'),5'-bisphosphate nucleotidase
PN96_RS12825	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
PN96_RS12830	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
PN96_RS12835	COG3156	type II secretion system protein K
PN96_RS12840	COG4795	General secretion pathway protein
PN96_RS12845	COG2165	general secretion pathway protein
PN96_RS12850	COG2165	general secretion pathway protein
PN96_RS12855	COG2165	general secretion pathway protein
PN96_RS12860	COG1459	type II secretion system
PN96_RS12865	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PN96_RS12875	COG3031	protein transport across the cell outer membrane
PN96_RS12880	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PN96_RS12885	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PN96_RS12890	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PN96_RS12900	COG0456	acetyltransferase
PN96_RS12905	COG1490	D-aminoacyl-tRNA deacylase activity
PN96_RS12910	COG1295	ribonuclease BN
PN96_RS12925	COG1217	gtp-binding protein TYPA
PN96_RS12930	COG0174	glutamine synthetase
PN96_RS12940	COG3852	Histidine kinase
PN96_RS12945	COG2204	response regulator
PN96_RS12955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PN96_RS12990	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PN96_RS12995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PN96_RS12995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PN96_RS13015	COG0084	hydrolase, TatD family'
PN96_RS13020	COG3263	regulation of cellular component size
PN96_RS13025	COG0805	protein transport
PN96_RS13030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PN96_RS13040	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PN96_RS13045	COG3165	ubiquinone biosynthetic process from chorismate
PN96_RS13050	COG2226	methyltransferase
PN96_RS13055	COG1322	Protein conserved in bacteria
PN96_RS13075	COG1132	(ABC) transporter
PN96_RS13080	COG4988	ABC transporter
PN96_RS13090	COG0748	coenzyme F420 binding
PN96_RS13140	COG4964	Belongs to the GSP D family
PN96_RS13170	COG2081	HI0933 family
PN96_RS13180	COG1528	Iron-storage protein
PN96_RS13185	COG0589	response to stress
PN96_RS13200	COG0742	ribosomal rna small subunit methyltransferase
PN96_RS13205	COG1522	sequence-specific DNA binding
PN96_RS13215	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PN96_RS13220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PN96_RS13225	COG3721	Heme iron utilization protein
PN96_RS13230	COG0800	Aldolase
PN96_RS13235	COG2610	gluconate transmembrane transporter activity
PN96_RS13240	COG3265	gluconokinase activity
PN96_RS13245	COG0129	dihydroxy-acid dehydratase activity
PN96_RS13250	COG1609	Transcriptional regulator
PN96_RS13260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PN96_RS13265	COG0601	transmembrane transport
PN96_RS13270	COG4166	transmembrane transport
PN96_RS13325	COG1309	transcriptional regulator
PN96_RS13330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PN96_RS13335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PN96_RS13340	COG2960	long-chain fatty acid transporting porin activity
PN96_RS13345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PN96_RS13350	COG0583	DNA-binding transcription factor activity
PN96_RS13360	COG2205	protein histidine kinase activity
PN96_RS13365	COG1263	PTS System
PN96_RS13365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PN96_RS13405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PN96_RS13410	COG1739	Uncharacterized protein family UPF0029
PN96_RS13415	COG1250	3-hydroxyacyl-CoA dehydrogenase
PN96_RS13415	COG1024	Enoyl-CoA hydratase
PN96_RS13420	COG0183	Belongs to the thiolase family
PN96_RS13425	COG0604	alcohol dehydrogenase
PN96_RS13440	COG0425	Belongs to the sulfur carrier protein TusA family
PN96_RS13450	COG2119	membrane
PN96_RS13460	COG0751	glycine-tRNA ligase activity
PN96_RS13465	COG0366	Alpha amylase catalytic
PN96_RS13470	COG3977	Valine--pyruvate aminotransferase
PN96_RS13475	COG0071	Belongs to the small heat shock protein (HSP20) family
PN96_RS13480	COG0187	DNA topoisomerase II activity
PN96_RS13485	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PN96_RS13490	COG0592	DNA-directed DNA polymerase activity
PN96_RS13510	COG1126	abc transporter atp-binding protein
PN96_RS13520	COG0594	ribonuclease P activity
PN96_RS13530	COG0706	membrane insertase activity
PN96_RS13540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PN96_RS13545	COG0445	tRNA wobble uridine modification
PN96_RS13555	COG1192	Involved in chromosome partitioning
PN96_RS13560	COG1475	DNA binding
PN96_RS13565	COG3312	ion transport
PN96_RS13570	COG0356	it plays a direct role in the translocation of protons across the membrane
PN96_RS13585	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PN96_RS13590	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PN96_RS13595	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PN96_RS13600	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PN96_RS13605	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PN96_RS13615	COG0765	amino acid transport
PN96_RS13620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PN96_RS13625	COG2814	Major facilitator Superfamily
PN96_RS13630	COG0583	DNA-binding transcription factor activity
PN96_RS13645	COG3978	acetolactate synthase activity
PN96_RS13655	COG0606	chelatase, subunit chli
PN96_RS13665	COG0204	Acyl-transferase
PN96_RS13670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PN96_RS13675	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PN96_RS13685	COG3084	Protein conserved in bacteria
PN96_RS13690	COG4326	sporulation control protein
PN96_RS13695	COG1272	protein, Hemolysin III
PN96_RS13705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PN96_RS13710	COG0569	domain protein
PN96_RS13715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PN96_RS13715	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PN96_RS13725	COG0242	peptide deformylase activity
PN96_RS13735	COG0758	DNA mediated transformation
PN96_RS13740	COG2922	Belongs to the Smg family
PN96_RS13745	COG0551	DNA topoisomerase type I activity
PN96_RS13750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PN96_RS13755	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PN96_RS13760	COG0009	L-threonylcarbamoyladenylate synthase
PN96_RS13765	COG0408	coproporphyrinogen oxidase activity
PN96_RS13770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PN96_RS13780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PN96_RS13830	COG2132	Multicopper oxidase
PN96_RS13835	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PN96_RS13840	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PN96_RS13850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PN96_RS13855	COG2104	thiamine diphosphate biosynthetic process
PN96_RS13860	COG2022	thiamine diphosphate biosynthetic process
PN96_RS13870	COG0006	proline dipeptidase activity
PN96_RS13870	COG0006	proline dipeptidase activity
PN96_RS13880	COG2814	Major facilitator Superfamily
PN96_RS13900	COG3220	belongs to the UPF0276 family
PN96_RS13910	COG0210	DNA helicase
PN96_RS13920	COG0405	Gamma-glutamyltransferase
PN96_RS13925	COG1280	lysine exporter protein (LysE YggA)
PN96_RS13935	COG2962	Rard protein
PN96_RS13940	COG0514	ATP-dependent DNA helicase (RecQ)
PN96_RS13950	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PN96_RS13955	COG0248	Ppx GppA phosphatase
PN96_RS13960	COG0513	Belongs to the DEAD box helicase family
PN96_RS13965	COG3118	belongs to the thioredoxin family
PN96_RS13980	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PN96_RS14035	COG3071	HemY protein
PN96_RS14040	COG2959	enzyme of heme biosynthesis
PN96_RS14045	COG1587	Uroporphyrinogen-III synthase
PN96_RS14050	COG0181	hydroxymethylbilane synthase activity
PN96_RS14055	COG3072	Adenylate cyclase
PN96_RS14060	COG1965	Belongs to the frataxin family
PN96_RS14070	COG0019	diaminopimelate decarboxylase activity
PN96_RS14075	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PN96_RS14085	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PN96_RS14090	COG1011	Hydrolase
PN96_RS14095	COG3148	PFAM DTW domain containing protein
PN96_RS14110	COG0561	phosphatase activity
PN96_RS14115	COG2267	carboxylic ester hydrolase activity
PN96_RS14120	COG1280	lysine exporter protein (LysE YggA)
PN96_RS14125	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
PN96_RS14130	COG0640	Transcriptional regulator
PN96_RS14135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PN96_RS14180	COG0742	ribosomal rna small subunit methyltransferase
PN96_RS14185	COG0552	protein localization to endoplasmic reticulum
PN96_RS14190	COG2884	Cell division ATP-binding protein ftsE
PN96_RS14195	COG2177	Part of the ABC transporter FtsEX involved in
PN96_RS14215	COG0705	Rhomboid family
PN96_RS14220	COG1580	Controls the rotational direction of flagella during chemotaxis
PN96_RS14225	COG3161	chorismate lyase activity
PN96_RS14230	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PN96_RS14235	COG2937	Belongs to the GPAT DAPAT family
PN96_RS14240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PN96_RS14245	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PN96_RS14250	COG0534	Mate efflux family protein
PN96_RS14255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PN96_RS14275	COG4206	TonB-dependent receptor
PN96_RS14350	COG3335	DDE superfamily endonuclease
PN96_RS14380	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
PN96_RS14385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PN96_RS14390	COG2264	protein methyltransferase activity
PN96_RS14395	COG0439	Biotin carboxylase
PN96_RS14400	COG0511	ligase activity, forming carbon-carbon bonds
PN96_RS14405	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PN96_RS14410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PN96_RS14425	COG2814	Major facilitator Superfamily
PN96_RS14430	COG2205	protein histidine kinase activity
PN96_RS14430	COG2198	Histidine kinase
PN96_RS14430	COG0784	Response regulator, receiver
PN96_RS14445	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PN96_RS14455	COG3263	regulation of cellular component size
PN96_RS14465	COG4232	protein-disulfide reductase activity
PN96_RS14470	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PN96_RS14475	COG1027	Aspartate ammonia-lyase
PN96_RS14480	COG3030	protein affecting phage T7 exclusion by the F plasmid
PN96_RS14485	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PN96_RS14490	COG2205	protein histidine kinase activity
PN96_RS14495	COG0745	RESPONSE REGULATOR receiver
PN96_RS14500	COG3678	ATP-independent chaperone mediated protein folding
PN96_RS14510	COG0205	6-phosphofructokinase activity
PN96_RS14515	COG0534	Mate efflux family protein
PN96_RS14550	COG1285	pathogenesis
PN96_RS14555	COG1509	lysine 2,3-aminomutase activity
PN96_RS14560	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PN96_RS14580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PN96_RS14585	COG1053	succinate dehydrogenase
PN96_RS14590	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
PN96_RS14610	COG4942	peptidase
PN96_RS14615	COG1045	serine acetyltransferase
PN96_RS14620	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PN96_RS14630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PN96_RS14635	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PN96_RS14645	COG0471	metal ion transport
PN96_RS14655	COG1162	GTPase activity
PN96_RS14660	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PN96_RS14725	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PN96_RS14730	COG0802	atpase or kinase
PN96_RS14735	COG0860	N-Acetylmuramoyl-L-alanine amidase
PN96_RS14740	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PN96_RS14745	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PN96_RS14755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PN96_RS14760	COG0330	HflC and HflK could
PN96_RS14765	COG0330	HflC and HflK could
PN96_RS14770	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
PN96_RS14775	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PN96_RS14780	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
PN96_RS14785	COG1017	nitric oxide dioxygenase activity
PN96_RS14785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PN96_RS14790	COG1959	2 iron, 2 sulfur cluster binding
PN96_RS14795	COG0557	exoribonuclease II activity
PN96_RS14800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PN96_RS14805	COG0546	phosphoglycolate phosphatase activity
PN96_RS14810	COG0180	Tryptophanyl-tRNA synthetase
PN96_RS14815	COG0512	Glutamine amidotransferase of anthranilate synthase
PN96_RS14820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PN96_RS14830	COG1012	belongs to the aldehyde dehydrogenase family
PN96_RS14840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PN96_RS14845	COG3954	Phosphoribulokinase
PN96_RS14850	COG3089	Belongs to the UPF0270 family
PN96_RS14855	COG0429	hydrolase of the alpha beta-hydrolase fold
PN96_RS14865	COG0488	(ABC) transporter
PN96_RS14870	COG2249	NAD(P)H dehydrogenase (quinone) activity
PN96_RS14885	COG1047	Peptidyl-prolyl cis-trans
PN96_RS14895	COG2900	Belongs to the SlyX family
PN96_RS14905	COG0545	Peptidyl-prolyl cis-trans isomerase
PN96_RS14910	COG2964	Protein conserved in bacteria
PN96_RS14915	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
PN96_RS14920	COG2923	Belongs to the DsrF TusC family
PN96_RS14940	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PN96_RS14960	COG0281	malic enzyme
PN96_RS14975	COG0626	cystathionine gamma-synthase activity
PN96_RS14980	COG0460	homoserine dehydrogenase
PN96_RS14980	COG0527	aspartate kinase activity
PN96_RS14985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PN96_RS14995	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PN96_RS15005	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PN96_RS15010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PN96_RS15015	COG0137	argininosuccinate synthase activity
PN96_RS15020	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PN96_RS15020	COG0165	Argininosuccinate lyase
PN96_RS15025	COG0678	peroxiredoxin activity
PN96_RS15025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PN96_RS15035	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PN96_RS15065	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PN96_RS15070	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PN96_RS15080	COG0338	D12 class N6 adenine-specific DNA methyltransferase
PN96_RS15085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PN96_RS15090	COG0360	Binds together with S18 to 16S ribosomal RNA
PN96_RS15095	COG2965	DNA replication, synthesis of RNA primer
PN96_RS15120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PN96_RS15125	COG0432	Pfam Uncharacterised protein family UPF0047
PN96_RS15130	COG0166	Belongs to the GPI family
PN96_RS15140	COG0735	belongs to the Fur family
PN96_RS15145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PN96_RS15165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PN96_RS15170	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PN96_RS15175	COG0175	sulfate reduction
PN96_RS15270	COG0085	RNA polymerase activity
PN96_RS15670	COG2239	Acts as a magnesium transporter
PN96_RS15880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PN96_RS15925	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PN96_RS15950	COG0126	phosphoglycerate kinase activity
PN96_RS16015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PN96_RS16045	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
PN96_RS16140	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PN96_RS16360	COG1752	Esterase of the alpha-beta hydrolase superfamily
PN96_RS16460	COG0747	negative chemotaxis
PN96_RS17030	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PN96_RS17045	COG1074	ATP-dependent DNA helicase activity
PN96_RS17065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PN96_RS17095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PN96_RS17265	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PN96_RS17340	COG0587	DNA-directed DNA polymerase activity
PN96_RS17440	COG2233	PERMEase
PN96_RS17530	COG2837	iron assimilation
PN96_RS17550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PN96_RS17795	COG2890	protein-(glutamine-N5) methyltransferase activity
PN96_RS18005	COG0252	asparaginase activity
PN96_RS18105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PN96_RS18150	COG1757	Na H antiporter
PN96_RS18180	COG1012	belongs to the aldehyde dehydrogenase family
PN96_RS18180	COG1454	alcohol dehydrogenase
PN96_RS18255	COG4656	Part of a membrane complex involved in electron transport
PN96_RS18385	COG0366	Alpha amylase catalytic
PN96_RS18575	COG0733	neurotransmitter:sodium symporter activity
PN96_RS18695	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PN96_RS18895	COG0159	tryptophan synthase activity
PN96_RS18980	COG0322	excinuclease ABC activity
PN96_RS19565	COG2204	response regulator
PN96_RS19740	COG5002	protein histidine kinase activity
PN96_RS19740	COG3850	Histidine kinase
PN96_RS20170	COG1012	belongs to the aldehyde dehydrogenase family
PN96_RS20515	COG0793	Belongs to the peptidase S41A family
PN96_RS20805	COG0243	molybdopterin cofactor binding
PN96_RS20805	COG3383	formate dehydrogenase (NAD+) activity
PN96_RS20985	COG1643	Atp-dependent helicase
PN96_RS21590	COG2195	Cleaves the N-terminal amino acid of tripeptides
PN96_RS21910	COG2925	Exonuclease
PN96_RS22110	COG1643	Atp-dependent helicase
PN96_RS22140	COG0492	ferredoxin-NADP+ reductase activity
PN96_RS22540	COG0243	molybdopterin cofactor binding
PN96_RS22550	COG0243	molybdopterin cofactor binding
PN96_RS22590	COG0215	cysteine-tRNA ligase activity
PN96_RS22620	COG0107	imidazoleglycerol-phosphate synthase activity
PN96_RS22635	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PN96_RS22790	COG1674	ftsk spoiiie
PN96_RS22875	COG3052	prosthetic group binding
PN96_RS23065	COG1801	Protein of unknown function DUF72
PN96_RS23075	COG0189	ligase activity
PN96_RS23075	COG4067	protein conserved in archaea
PN96_RS23235	COG1199	ATP-dependent helicase activity
PN96_RS23415	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site