locus-tag	class	description
GPY30_RS00005	COG0561	phosphatase activity
GPY30_RS00030	COG1011	Hydrolase
GPY30_RS00050	COG0019	diaminopimelate decarboxylase activity
GPY30_RS00065	COG3072	Adenylate cyclase
GPY30_RS00080	COG2959	enzyme of heme biosynthesis
GPY30_RS00135	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GPY30_RS00145	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPY30_RS00150	COG3118	belongs to the thioredoxin family
GPY30_RS00165	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPY30_RS00175	COG0514	ATP-dependent DNA helicase (RecQ)
GPY30_RS00180	COG2962	Rard protein
GPY30_RS00190	COG1280	lysine exporter protein (LysE YggA)
GPY30_RS00195	COG0210	DNA helicase
GPY30_RS00205	COG3220	belongs to the UPF0276 family
GPY30_RS00235	COG0006	proline dipeptidase activity
GPY30_RS00235	COG0006	proline dipeptidase activity
GPY30_RS00240	COG3344	reverse transcriptase
GPY30_RS00245	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPY30_RS00260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY30_RS00265	COG0352	thiamine-phosphate diphosphorylase activity
GPY30_RS00280	COG3335	DDE superfamily endonuclease
GPY30_RS00325	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPY30_RS00335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPY30_RS00340	COG0408	coproporphyrinogen oxidase activity
GPY30_RS00345	COG0009	L-threonylcarbamoyladenylate synthase
GPY30_RS00360	COG0551	DNA topoisomerase type I activity
GPY30_RS00370	COG0758	DNA mediated transformation
GPY30_RS00385	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPY30_RS00390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPY30_RS00390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPY30_RS00395	COG0569	domain protein
GPY30_RS00400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY30_RS00410	COG1272	protein, Hemolysin III
GPY30_RS00415	COG4326	sporulation control protein
GPY30_RS00420	COG3084	Protein conserved in bacteria
GPY30_RS00430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPY30_RS00435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY30_RS00440	COG0204	Acyl-transferase
GPY30_RS00450	COG0606	chelatase, subunit chli
GPY30_RS00460	COG3978	acetolactate synthase activity
GPY30_RS00465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPY30_RS00480	COG0583	DNA-binding transcription factor activity
GPY30_RS00505	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPY30_RS00535	COG3312	ion transport
GPY30_RS00540	COG1475	DNA binding
GPY30_RS00545	COG1192	Involved in chromosome partitioning
GPY30_RS00550	COG0357	Ribosomal RNA small subunit methyltransferase G
GPY30_RS00555	COG0445	tRNA wobble uridine modification
GPY30_RS00560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY30_RS00570	COG0706	membrane insertase activity
GPY30_RS00575	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GPY30_RS00590	COG1126	abc transporter atp-binding protein
GPY30_RS00610	COG0592	DNA-directed DNA polymerase activity
GPY30_RS00620	COG0187	DNA topoisomerase II activity
GPY30_RS00625	COG0071	Belongs to the small heat shock protein (HSP20) family
GPY30_RS00630	COG3977	Valine--pyruvate aminotransferase
GPY30_RS00635	COG0751	glycine-tRNA ligase activity
GPY30_RS00640	COG0752	glycyl-tRNA synthetase alpha subunit
GPY30_RS00645	COG2119	membrane
GPY30_RS00670	COG0655	NAD(P)H dehydrogenase (quinone) activity
GPY30_RS00675	COG0583	DNA-binding transcription factor activity
GPY30_RS00695	COG0604	alcohol dehydrogenase
GPY30_RS00700	COG0183	Belongs to the thiolase family
GPY30_RS00710	COG1739	Uncharacterized protein family UPF0029
GPY30_RS00715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY30_RS00720	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
GPY30_RS00755	COG3335	DDE superfamily endonuclease
GPY30_RS00760	COG0583	DNA-binding transcription factor activity
GPY30_RS00770	COG2960	long-chain fatty acid transporting porin activity
GPY30_RS00775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY30_RS00780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY30_RS00785	COG1309	transcriptional regulator
GPY30_RS00825	COG4172	Belongs to the ABC transporter superfamily
GPY30_RS00830	COG4166	transmembrane transport
GPY30_RS00840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY30_RS00875	COG2815	serine threonine protein kinase
GPY30_RS00875	COG0515	serine threonine protein kinase
GPY30_RS00890	COG1609	Transcriptional regulator
GPY30_RS00895	COG0129	dihydroxy-acid dehydratase activity
GPY30_RS00900	COG3265	gluconokinase activity
GPY30_RS00905	COG2610	gluconate transmembrane transporter activity
GPY30_RS00910	COG0800	Aldolase
GPY30_RS00925	COG2814	Major facilitator Superfamily
GPY30_RS00940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY30_RS00945	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GPY30_RS00955	COG1522	sequence-specific DNA binding
GPY30_RS00960	COG5002	protein histidine kinase activity
GPY30_RS00960	COG5001	Diguanylate cyclase
GPY30_RS00980	COG0589	response to stress
GPY30_RS00985	COG1528	Iron-storage protein
GPY30_RS00995	COG2081	HI0933 family
GPY30_RS01005	COG3433	isochorismatase activity
GPY30_RS01005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY30_RS01005	COG2226	methyltransferase
GPY30_RS01045	COG1322	Protein conserved in bacteria
GPY30_RS01060	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GPY30_RS01075	COG0805	protein transport
GPY30_RS01080	COG0084	hydrolase, TatD family'
GPY30_RS01095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY30_RS01095	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY30_RS01115	COG3078	GTPase activator activity
GPY30_RS01125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY30_RS01130	COG5001	Diguanylate cyclase
GPY30_RS01130	COG3706	GGDEF domain
GPY30_RS01130	COG4251	negative regulation of phosphorylation
GPY30_RS01130	COG2203	Gaf domain
GPY30_RS01135	COG2204	response regulator
GPY30_RS01140	COG3852	Histidine kinase
GPY30_RS01150	COG0174	glutamine synthetase
GPY30_RS01175	COG0456	acetyltransferase
GPY30_RS01195	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GPY30_RS01200	COG3031	protein transport across the cell outer membrane
GPY30_RS01210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY30_RS01215	COG1459	type II secretion system
GPY30_RS01220	COG2165	general secretion pathway protein
GPY30_RS01230	COG2165	general secretion pathway protein
GPY30_RS01235	COG4795	General secretion pathway protein
GPY30_RS01240	COG3156	type II secretion system protein K
GPY30_RS01245	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPY30_RS01250	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPY30_RS01260	COG1218	3'(2'),5'-bisphosphate nucleotidase
GPY30_RS01275	COG1040	competence protein
GPY30_RS01290	COG2183	response to ionizing radiation
GPY30_RS01305	COG1288	antiporter activity
GPY30_RS01310	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPY30_RS01320	COG0745	RESPONSE REGULATOR receiver
GPY30_RS01330	COG2233	PERMEase
GPY30_RS01340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY30_RS01345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY30_RS01350	COG1758	RNA polymerase activity
GPY30_RS01370	COG0848	biopolymer transport protein
GPY30_RS01375	COG0811	peptide transport
GPY30_RS01380	COG0811	peptide transport
GPY30_RS01395	COG4174	ABC transporter (Permease)
GPY30_RS01400	COG4239	(ABC) transporter, permease
GPY30_RS01405	COG0747	negative chemotaxis
GPY30_RS01410	COG0444	Belongs to the ABC transporter superfamily
GPY30_RS01415	COG4608	Belongs to the ABC transporter superfamily
GPY30_RS01430	COG4264	IucA IucC family
GPY30_RS01435	COG2814	Major facilitator Superfamily
GPY30_RS01450	COG4774	siderophore transport
GPY30_RS01455	COG4772	TonB-dependent receptor
GPY30_RS01460	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GPY30_RS01465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY30_RS01470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY30_RS01475	COG1120	ATPase activity
GPY30_RS01480	COG1561	YicC-like family, N-terminal region
GPY30_RS01495	COG1560	Kdo2-lipid A biosynthetic process
GPY30_RS01505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPY30_RS01510	COG0840	transmembrane signaling receptor activity
GPY30_RS01515	COG2003	Belongs to the UPF0758 family
GPY30_RS01555	COG0859	PFAM glycosyl transferase family 9
GPY30_RS01560	COG0463	Glycosyl transferase, family 2
GPY30_RS01565	COG0859	PFAM glycosyl transferase family 9
GPY30_RS01570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPY30_RS01575	COG3642	lipopolysaccharide core region biosynthetic process
GPY30_RS01595	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GPY30_RS01605	COG2089	acid synthase
GPY30_RS01610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GPY30_RS01650	COG1519	Transferase
GPY30_RS01655	COG0859	PFAM glycosyl transferase family 9
GPY30_RS01660	COG1560	Kdo2-lipid A biosynthetic process
GPY30_RS01680	COG1404	Belongs to the peptidase S8 family
GPY30_RS01695	COG1596	polysaccharide export
GPY30_RS01705	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPY30_RS01710	COG3206	protein involved in exopolysaccharide biosynthesis
GPY30_RS01710	COG0489	protein tyrosine kinase activity
GPY30_RS01715	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GPY30_RS01720	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GPY30_RS01730	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPY30_RS01745	COG1086	Polysaccharide biosynthesis protein
GPY30_RS01770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GPY30_RS01785	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GPY30_RS01790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPY30_RS01795	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GPY30_RS01820	COG1494	fructose-1,6-bisphosphatase
GPY30_RS01835	COG1575	Belongs to the MenA family. Type 1 subfamily
GPY30_RS01855	COG1609	Transcriptional regulator
GPY30_RS01860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPY30_RS01865	COG0254	rRNA binding
GPY30_RS01870	COG0281	malic enzyme
GPY30_RS01880	COG0626	cystathionine gamma-synthase activity
GPY30_RS01885	COG0527	aspartate kinase activity
GPY30_RS01885	COG0460	homoserine dehydrogenase
GPY30_RS01890	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPY30_RS01900	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GPY30_RS01905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY30_RS01910	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPY30_RS01925	COG0165	Argininosuccinate lyase
GPY30_RS01925	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPY30_RS01940	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GPY30_RS01985	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GPY30_RS01990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPY30_RS02015	COG0305	Participates in initiation and elongation during chromosome replication
GPY30_RS02020	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY30_RS02030	COG0432	Pfam Uncharacterised protein family UPF0047
GPY30_RS02045	COG0735	belongs to the Fur family
GPY30_RS02080	COG0175	sulfate reduction
GPY30_RS02150	COG0589	response to stress
GPY30_RS02170	COG0039	L-malate dehydrogenase activity
GPY30_RS02180	COG0142	geranyltranstransferase activity
GPY30_RS02185	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GPY30_RS02195	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPY30_RS02200	COG2966	Psort location CytoplasmicMembrane, score
GPY30_RS02205	COG3610	response to peptide
GPY30_RS02240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GPY30_RS02265	COG0066	3-isopropylmalate dehydratase activity
GPY30_RS02275	COG0473	3-isopropylmalate dehydrogenase activity
GPY30_RS02285	COG1309	transcriptional regulator
GPY30_RS02310	COG0028	Belongs to the TPP enzyme family
GPY30_RS02315	COG0440	acetolactate synthase activity
GPY30_RS02320	COG3706	GGDEF domain
GPY30_RS02325	COG1802	Transcriptional regulator
GPY30_RS02330	COG0469	pyruvate kinase activity
GPY30_RS02335	COG1349	DNA-binding transcription factor activity
GPY30_RS02350	COG3722	fumarate hydratase activity
GPY30_RS02360	COG2213	PTS system mannitol-specific
GPY30_RS02360	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY30_RS02365	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPY30_RS02385	COG3550	peptidyl-serine autophosphorylation
GPY30_RS02400	COG2378	regulation of single-species biofilm formation
GPY30_RS02480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPY30_RS02485	COG0358	DNA primase activity
GPY30_RS02490	COG1610	YqeY-like protein
GPY30_RS02495	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GPY30_RS02515	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPY30_RS02520	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY30_RS02530	COG0617	tRNA 3'-terminal CCA addition
GPY30_RS02535	COG3267	Type II secretory pathway component ExeA
GPY30_RS02535	COG3409	Peptidoglycan-binding domain 1 protein
GPY30_RS02540	COG4991	sh3 domain protein
GPY30_RS02545	COG0306	phosphate transporter
GPY30_RS02550	COG1392	Phosphate transport regulator
GPY30_RS02555	COG3025	triphosphatase activity
GPY30_RS02570	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GPY30_RS02580	COG1538	Outer membrane efflux protein
GPY30_RS02585	COG0494	nUDIX hydrolase
GPY30_RS02590	COG3151	Protein conserved in bacteria
GPY30_RS02600	COG3150	esterase
GPY30_RS02605	COG0187	DNA topoisomerase II activity
GPY30_RS02615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPY30_RS02620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPY30_RS02625	COG3105	Protein conserved in bacteria
GPY30_RS02630	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GPY30_RS02650	COG0723	plastoquinol--plastocyanin reductase activity
GPY30_RS02655	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GPY30_RS02660	COG2857	Cytochrome c1
GPY30_RS02665	COG0625	glutathione transferase activity
GPY30_RS02670	COG2969	positive regulation of protein catabolic process
GPY30_RS02675	COG2823	Periplasmic or secreted lipoprotein
GPY30_RS02680	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPY30_RS02690	COG3107	peptidoglycan biosynthetic process
GPY30_RS02695	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPY30_RS02710	COG3116	cell division
GPY30_RS02715	COG0768	penicillin binding
GPY30_RS02730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPY30_RS02740	COG0772	Belongs to the SEDS family
GPY30_RS02745	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPY30_RS02755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GPY30_RS02760	COG0849	cell division
GPY30_RS02765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPY30_RS02770	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GPY30_RS02775	COG3344	reverse transcriptase
GPY30_RS02780	COG0653	protein targeting
GPY30_RS02785	COG0494	nUDIX hydrolase
GPY30_RS02795	COG0505	Belongs to the CarA family
GPY30_RS02805	COG0730	response to heat
GPY30_RS02810	COG0583	DNA-binding transcription factor activity
GPY30_RS02815	COG2860	membrane
GPY30_RS02830	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPY30_RS02840	COG0493	'glutamate synthase
GPY30_RS02845	COG0067	glutamate synthase
GPY30_RS02845	COG0070	glutamate synthase
GPY30_RS02845	COG0069	glutamate synthase activity
GPY30_RS02855	COG0070	glutamate synthase
GPY30_RS02855	COG0069	glutamate synthase activity
GPY30_RS02855	COG0067	glutamate synthase
GPY30_RS02860	COG1242	4 iron, 4 sulfur cluster binding
GPY30_RS02865	COG5001	Diguanylate cyclase
GPY30_RS02865	COG4251	negative regulation of phosphorylation
GPY30_RS02865	COG3706	GGDEF domain
GPY30_RS02865	COG2203	Gaf domain
GPY30_RS02870	COG0784	Response regulator, receiver
GPY30_RS02870	COG2198	Histidine kinase
GPY30_RS02870	COG5002	protein histidine kinase activity
GPY30_RS02880	COG0745	RESPONSE REGULATOR receiver
GPY30_RS02915	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPY30_RS02930	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPY30_RS02945	COG1115	amino acid carrier protein
GPY30_RS02950	COG3022	response to hydroperoxide
GPY30_RS02955	COG0513	Belongs to the DEAD box helicase family
GPY30_RS02970	COG0716	FMN binding
GPY30_RS02980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY30_RS02985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GPY30_RS02995	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GPY30_RS03000	COG2204	response regulator
GPY30_RS03010	COG0667	Aldo Keto reductase
GPY30_RS03055	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPY30_RS03065	COG0640	Transcriptional regulator
GPY30_RS03075	COG0728	peptidoglycan biosynthetic process
GPY30_RS03080	COG0196	riboflavin kinase activity
GPY30_RS03085	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPY30_RS03090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPY30_RS03095	COG1047	Peptidyl-prolyl cis-trans
GPY30_RS03105	COG3344	reverse transcriptase
GPY30_RS03115	COG3275	phosphorelay sensor kinase activity
GPY30_RS03120	COG1966	Carbon starvation protein
GPY30_RS03140	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GPY30_RS03145	COG1472	Belongs to the glycosyl hydrolase 3 family
GPY30_RS03150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY30_RS03160	COG0739	heme binding
GPY30_RS03170	COG0488	(ABC) transporter
GPY30_RS03190	COG0077	Prephenate dehydratase
GPY30_RS03190	COG1605	Chorismate mutase
GPY30_RS03195	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY30_RS03200	COG3344	reverse transcriptase
GPY30_RS03205	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY30_RS03265	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPY30_RS03280	COG0745	RESPONSE REGULATOR receiver
GPY30_RS03285	COG5002	protein histidine kinase activity
GPY30_RS03295	COG0248	Ppx GppA phosphatase
GPY30_RS03310	COG0581	inorganic phosphate transmembrane transporter activity
GPY30_RS03315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY30_RS03320	COG0704	Plays a role in the regulation of phosphate uptake
GPY30_RS03335	COG0450	alkyl hydroperoxide reductase
GPY30_RS03340	COG0583	DNA-binding transcription factor activity
GPY30_RS03345	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GPY30_RS03355	COG0517	IMP dehydrogenase activity
GPY30_RS03375	COG1862	Preprotein translocase
GPY30_RS03380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY30_RS03390	COG0483	inositol monophosphate 1-phosphatase activity
GPY30_RS03395	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GPY30_RS03405	COG1104	cysteine desulfurase activity
GPY30_RS03410	COG0822	iron-sulfur transferase activity
GPY30_RS03420	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPY30_RS03425	COG0443	Heat shock 70 kDa protein
GPY30_RS03430	COG0633	Ferredoxin
GPY30_RS03435	COG2975	iron-sulfur cluster assembly
GPY30_RS03455	COG1426	Protein conserved in bacteria
GPY30_RS03470	COG2976	Protein conserved in bacteria
GPY30_RS03475	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY30_RS03480	COG1160	GTP binding
GPY30_RS03500	COG0516	GMP reductase activity
GPY30_RS03500	COG0517	IMP dehydrogenase activity
GPY30_RS03505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GPY30_RS03505	COG0519	Catalyzes the synthesis of GMP from XMP
GPY30_RS03515	COG3344	reverse transcriptase
GPY30_RS03520	COG1584	GPR1 FUN34 yaaH family protein
GPY30_RS03530	COG0583	DNA-binding transcription factor activity
GPY30_RS03535	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GPY30_RS03550	COG0583	DNA-binding transcription factor activity
GPY30_RS03565	COG0586	Pfam SNARE associated Golgi protein
GPY30_RS03570	COG0009	L-threonylcarbamoyladenylate synthase
GPY30_RS03585	COG0697	spore germination
GPY30_RS03655	COG2003	Belongs to the UPF0758 family
GPY30_RS03725	COG0515	serine threonine protein kinase
GPY30_RS03725	COG2815	serine threonine protein kinase
GPY30_RS03755	COG2867	negative regulation of translational initiation
GPY30_RS03765	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY30_RS03770	COG0497	DNA recombination
GPY30_RS03780	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPY30_RS03795	COG0484	heat shock protein binding
GPY30_RS03825	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY30_RS03830	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GPY30_RS03835	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GPY30_RS03840	COG0583	DNA-binding transcription factor activity
GPY30_RS03845	COG0590	tRNA wobble adenosine to inosine editing
GPY30_RS03880	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY30_RS03885	COG2252	PERMEase
GPY30_RS03910	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPY30_RS03915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPY30_RS03920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY30_RS03920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY30_RS03950	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GPY30_RS03955	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPY30_RS03960	COG0142	geranyltranstransferase activity
GPY30_RS03970	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPY30_RS03980	COG0301	tRNA thio-modification
GPY30_RS03980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY30_RS03985	COG0583	DNA-binding transcription factor activity
GPY30_RS04010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY30_RS04015	COG1611	Belongs to the LOG family
GPY30_RS04030	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPY30_RS04030	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPY30_RS04040	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GPY30_RS04045	COG1464	Belongs to the NlpA lipoprotein family
GPY30_RS04050	COG2011	ABC-type metal ion transport system permease component
GPY30_RS04055	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPY30_RS04060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPY30_RS04065	COG1609	Transcriptional regulator
GPY30_RS04070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY30_RS04070	COG1263	PTS System
GPY30_RS04075	COG0366	Alpha amylase catalytic
GPY30_RS04120	COG1686	Belongs to the peptidase S11 family
GPY30_RS04125	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPY30_RS04130	COG0772	Belongs to the SEDS family
GPY30_RS04140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPY30_RS04145	COG0799	negative regulation of ribosome biogenesis
GPY30_RS04150	COG1466	dna polymerase III delta subunit
GPY30_RS04155	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GPY30_RS04165	COG2888	peptidyl-tyrosine sulfation
GPY30_RS04175	COG4535	Mg2 and Co2 transporter CorC
GPY30_RS04180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPY30_RS04185	COG1702	phosphate starvation-inducible protein PhoH
GPY30_RS04190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPY30_RS04195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY30_RS04200	COG3385	transposase activity
GPY30_RS04305	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPY30_RS04310	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GPY30_RS04325	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY30_RS04330	COG3094	Invasion gene expression up-regulator, SirB
GPY30_RS04335	COG2912	Transglutaminase-like superfamily
GPY30_RS04340	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GPY30_RS04350	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPY30_RS04355	COG1187	pseudouridine synthase activity
GPY30_RS04360	COG2840	Smr protein MutS2
GPY30_RS04390	COG2608	mercury ion transmembrane transporter activity
GPY30_RS04390	COG2217	Heavy metal translocating P-type atpase
GPY30_RS04450	COG0835	chemotaxis
GPY30_RS04450	COG0784	Response regulator, receiver
GPY30_RS04455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPY30_RS04460	COG1815	bacterial-type flagellum-dependent cell motility
GPY30_RS04465	COG1558	bacterial-type flagellum-dependent cell motility
GPY30_RS04470	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPY30_RS04480	COG4787	bacterial-type flagellum-dependent cell motility
GPY30_RS04485	COG4786	Flagellar basal body rod
GPY30_RS04500	COG3951	Flagellar rod assembly protein muramidase FlgJ
GPY30_RS04500	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPY30_RS04510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY30_RS04515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY30_RS04520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY30_RS04525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY30_RS04530	COG2190	(PTS) system
GPY30_RS04535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPY30_RS04540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY30_RS04545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPY30_RS04550	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GPY30_RS04585	COG3118	belongs to the thioredoxin family
GPY30_RS04595	COG0300	oxidoreductase activity
GPY30_RS04600	COG1090	epimerase
GPY30_RS04625	COG0622	Phosphoesterase
GPY30_RS04645	COG3710	Transcriptional regulator
GPY30_RS04660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GPY30_RS04665	COG3104	oligopeptide transport
GPY30_RS04675	COG0367	asparagine synthase
GPY30_RS04685	COG1846	Transcriptional regulator
GPY30_RS04685	COG1940	carbohydrate kinase activity
GPY30_RS04690	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPY30_RS04695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY30_RS04695	COG2190	(PTS) system
GPY30_RS04695	COG1263	PTS System
GPY30_RS04700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY30_RS04715	COG0583	DNA-binding transcription factor activity
GPY30_RS04720	COG1380	Effector of murein hydrolase LrgA
GPY30_RS04725	COG1346	cytolysis
GPY30_RS04730	COG0716	FMN binding
GPY30_RS04750	COG0033	Phosphoglucomutase
GPY30_RS04760	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPY30_RS04770	COG2009	succinate dehydrogenase
GPY30_RS04775	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GPY30_RS04780	COG1053	succinate dehydrogenase
GPY30_RS04790	COG0567	Dehydrogenase, E1 component
GPY30_RS04795	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY30_RS04810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPY30_RS04820	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GPY30_RS04830	COG1918	ferrous iron import across plasma membrane
GPY30_RS04835	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GPY30_RS04855	COG3102	Protein conserved in bacteria
GPY30_RS04860	COG0788	formyltetrahydrofolate deformylase activity
GPY30_RS04870	COG1199	ATP-dependent helicase activity
GPY30_RS04875	COG1214	PFAM Peptidase M22, glycoprotease
GPY30_RS04890	COG2267	carboxylic ester hydrolase activity
GPY30_RS04895	COG0318	PFAM AMP-dependent synthetase and ligase
GPY30_RS04900	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GPY30_RS04910	COG2894	cell division
GPY30_RS04920	COG3100	YcgL domain-containing protein
GPY30_RS04925	COG2951	lytic endotransglycosylase activity
GPY30_RS04930	COG0583	DNA-binding transcription factor activity
GPY30_RS04935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY30_RS04950	COG1028	Short-chain dehydrogenase reductase Sdr
GPY30_RS04985	COG2986	histidine ammonia-lyase
GPY30_RS04990	COG1216	Glycosyl transferase, family 2
GPY30_RS05010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY30_RS05015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY30_RS05055	COG0745	RESPONSE REGULATOR receiver
GPY30_RS05060	COG2205	protein histidine kinase activity
GPY30_RS05075	COG0395	ABC-type sugar transport system, permease component
GPY30_RS05080	COG3842	ATPase activity
GPY30_RS05085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPY30_RS05090	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GPY30_RS05095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GPY30_RS05105	COG4191	Histidine kinase
GPY30_RS05130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPY30_RS05135	COG0776	regulation of translation
GPY30_RS05140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY30_RS05165	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GPY30_RS05175	COG1169	isochorismate synthase
GPY30_RS05180	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GPY30_RS05185	COG0596	Alpha beta hydrolase
GPY30_RS05190	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPY30_RS05195	COG1441	menaquinone biosynthetic process
GPY30_RS05215	COG0477	Major facilitator Superfamily
GPY30_RS05255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY30_RS05270	COG1522	sequence-specific DNA binding
GPY30_RS05275	COG1946	Acyl-CoA thioesterase
GPY30_RS05310	COG2203	Gaf domain
GPY30_RS05310	COG2199	diguanylate cyclase activity
GPY30_RS05335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY30_RS05335	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPY30_RS05360	COG0517	IMP dehydrogenase activity
GPY30_RS05360	COG0516	GMP reductase activity
GPY30_RS05370	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GPY30_RS05385	COG0537	adenosine 5'-monophosphoramidase activity
GPY30_RS05415	COG1252	NADH dehydrogenase
GPY30_RS05435	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPY30_RS05445	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPY30_RS05450	COG1136	(ABC) transporter
GPY30_RS05455	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPY30_RS05465	COG0658	competence protein
GPY30_RS05465	COG2333	competence protein COMEC
GPY30_RS05470	COG1132	(ABC) transporter
GPY30_RS05485	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GPY30_RS05490	COG2719	SpoVR family
GPY30_RS05495	COG2718	Belongs to the UPF0229 family
GPY30_RS05515	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY30_RS05530	COG1882	Formate acetyltransferase
GPY30_RS05555	COG4215	(ABC) transporter
GPY30_RS05560	COG4160	amino acid transport
GPY30_RS05575	COG0840	transmembrane signaling receptor activity
GPY30_RS05585	COG3923	Primosomal replication protein n
GPY30_RS05595	COG1199	ATP-dependent helicase activity
GPY30_RS05620	COG1278	Cold shock
GPY30_RS05635	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPY30_RS05640	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GPY30_RS05665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY30_RS05670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPY30_RS05675	COG0297	glycogen (starch) synthase activity
GPY30_RS05695	COG3070	regulator of competence-specific genes
GPY30_RS05705	COG3381	protein complex oligomerization
GPY30_RS05710	COG0745	RESPONSE REGULATOR receiver
GPY30_RS05715	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPY30_RS05720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY30_RS05735	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GPY30_RS05755	COG4067	protein conserved in archaea
GPY30_RS05755	COG0189	ligase activity
GPY30_RS05770	COG1801	Protein of unknown function DUF72
GPY30_RS05785	COG0840	transmembrane signaling receptor activity
GPY30_RS05795	COG2255	four-way junction helicase activity
GPY30_RS05800	COG1271	oxidase subunit
GPY30_RS05805	COG1294	oxidase, subunit
GPY30_RS05810	COG4890	Cyd operon protein YbgT
GPY30_RS05820	COG0824	Thioesterase
GPY30_RS05825	COG0811	peptide transport
GPY30_RS05840	COG0823	Involved in the tonB-independent uptake of proteins
GPY30_RS05845	COG2885	chlorophyll binding
GPY30_RS05850	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GPY30_RS05855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GPY30_RS05860	COG0137	argininosuccinate synthase activity
GPY30_RS05865	COG3766	membrane
GPY30_RS05875	COG0754	glutathionylspermidine amidase activity
GPY30_RS05890	COG1858	cytochrome C peroxidase
GPY30_RS05910	COG5002	protein histidine kinase activity
GPY30_RS05910	COG0784	Response regulator, receiver
GPY30_RS05935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPY30_RS05955	COG1482	cell wall glycoprotein biosynthetic process
GPY30_RS05960	COG2271	Major facilitator Superfamily
GPY30_RS05965	COG3851	Histidine kinase
GPY30_RS05970	COG2197	response regulator
GPY30_RS05980	COG1858	cytochrome C peroxidase
GPY30_RS05995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY30_RS06000	COG0840	transmembrane signaling receptor activity
GPY30_RS06010	COG0415	Belongs to the DNA photolyase family
GPY30_RS06015	COG2199	diguanylate cyclase activity
GPY30_RS06015	COG2203	Gaf domain
GPY30_RS06085	COG0583	DNA-binding transcription factor activity
GPY30_RS06100	COG2350	Protein conserved in bacteria
GPY30_RS06105	COG1607	acyl-coa hydrolase
GPY30_RS06120	COG1301	dicarboxylic acid transport
GPY30_RS06125	COG0159	tryptophan synthase activity
GPY30_RS06135	COG0135	phosphoribosylanthranilate isomerase activity
GPY30_RS06135	COG0134	indole-3-glycerol-phosphate synthase activity
GPY30_RS06145	COG0512	Glutamine amidotransferase of anthranilate synthase
GPY30_RS06150	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY30_RS06160	COG0613	PHP domain protein
GPY30_RS06165	COG0009	L-threonylcarbamoyladenylate synthase
GPY30_RS06195	COG0417	DNA replication proofreading
GPY30_RS06200	COG2197	response regulator
GPY30_RS06205	COG0322	excinuclease ABC activity
GPY30_RS06270	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY30_RS06275	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY30_RS06295	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY30_RS06320	COG2989	Protein conserved in bacteria
GPY30_RS06325	COG3108	Peptidase M15
GPY30_RS06330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY30_RS06370	COG1846	Transcriptional regulator
GPY30_RS06375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY30_RS06380	COG0840	transmembrane signaling receptor activity
GPY30_RS06400	COG1448	Aminotransferase
GPY30_RS06405	COG3437	response regulator, receiver
GPY30_RS06405	COG2770	Histidine kinase
GPY30_RS06415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY30_RS06435	COG0720	synthase
GPY30_RS06445	COG1538	Outer membrane efflux protein
GPY30_RS06450	COG0577	efflux transmembrane transporter activity
GPY30_RS06450	COG1136	(ABC) transporter
GPY30_RS06455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY30_RS06460	COG1760	l-serine dehydratase
GPY30_RS06465	COG0814	amino acid
GPY30_RS06470	COG0494	nUDIX hydrolase
GPY30_RS06490	COG3106	COG3106 Predicted ATPase
GPY30_RS06495	COG3768	UPF0283 membrane protein
GPY30_RS06505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY30_RS06520	COG0471	metal ion transport
GPY30_RS06525	COG4191	Histidine kinase
GPY30_RS06525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY30_RS06530	COG2204	response regulator
GPY30_RS06535	COG3706	GGDEF domain
GPY30_RS06540	COG5001	Diguanylate cyclase
GPY30_RS06555	COG5001	Diguanylate cyclase
GPY30_RS06555	COG3300	MHYT domain
GPY30_RS06560	COG1328	CTP reductase activity
GPY30_RS06565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY30_RS06580	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPY30_RS06590	COG1597	lipid kinase activity
GPY30_RS06595	COG0814	amino acid
GPY30_RS06605	COG0783	Belongs to the Dps family
GPY30_RS06620	COG1132	(ABC) transporter
GPY30_RS06625	COG1132	(ABC) transporter
GPY30_RS06630	COG1115	amino acid carrier protein
GPY30_RS06650	COG3568	Endonuclease Exonuclease Phosphatase
GPY30_RS06665	COG1280	lysine exporter protein (LysE YggA)
GPY30_RS06670	COG0443	Heat shock 70 kDa protein
GPY30_RS06710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPY30_RS06715	COG1643	Atp-dependent helicase
GPY30_RS06740	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPY30_RS06750	COG2814	Major facilitator Superfamily
GPY30_RS06755	COG0010	Belongs to the arginase family
GPY30_RS06805	COG3706	GGDEF domain
GPY30_RS06805	COG0745	RESPONSE REGULATOR receiver
GPY30_RS06815	COG0072	phenylalanine-tRNA ligase activity
GPY30_RS06815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY30_RS06820	COG2200	EAL domain
GPY30_RS06825	COG2200	EAL domain
GPY30_RS06870	COG1346	cytolysis
GPY30_RS06875	COG1380	Effector of murein hydrolase LrgA
GPY30_RS06880	COG2925	Exonuclease
GPY30_RS06885	COG0702	epimerase
GPY30_RS06895	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GPY30_RS06915	COG2988	succinylglutamate desuccinylase activity
GPY30_RS06925	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GPY30_RS06955	COG1451	nucleotide metabolic process
GPY30_RS06970	COG3063	Type IV pilus biogenesis stability protein PilW
GPY30_RS06980	COG0243	molybdopterin cofactor binding
GPY30_RS06985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPY30_RS06985	COG1648	precorrin-2 dehydrogenase activity
GPY30_RS06990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPY30_RS06995	COG3707	response regulator
GPY30_RS07000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GPY30_RS07000	COG1116	anion transmembrane transporter activity
GPY30_RS07005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GPY30_RS07010	COG1116	anion transmembrane transporter activity
GPY30_RS07015	COG2146	nitrite reductase [NAD(P)H] activity
GPY30_RS07015	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPY30_RS07020	COG2146	nitrite reductase [NAD(P)H] activity
GPY30_RS07035	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GPY30_RS07045	COG0625	glutathione transferase activity
GPY30_RS07075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPY30_RS07080	COG2146	nitrite reductase [NAD(P)H] activity
GPY30_RS07095	COG1278	Cold shock
GPY30_RS07110	COG0730	response to heat
GPY30_RS07135	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPY30_RS07140	COG0372	Belongs to the citrate synthase family
GPY30_RS07145	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GPY30_RS07170	COG0561	phosphatase activity
GPY30_RS07175	COG0602	queuosine metabolic process
GPY30_RS07180	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPY30_RS07185	COG3447	MASE1 domain protein
GPY30_RS07185	COG5001	Diguanylate cyclase
GPY30_RS07185	COG5002	protein histidine kinase activity
GPY30_RS07215	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY30_RS07225	COG1254	Belongs to the acylphosphatase family
GPY30_RS07230	COG2920	part of a sulfur-relay system
GPY30_RS07235	COG0670	Belongs to the BI1 family
GPY30_RS07240	COG1126	abc transporter atp-binding protein
GPY30_RS07245	COG0765	amino acid transport
GPY30_RS07250	COG4597	amino acid ABC transporter
GPY30_RS07255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY30_RS07270	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY30_RS07295	COG2996	Protein conserved in bacteria
GPY30_RS07305	COG3008	intermembrane lipid transfer
GPY30_RS07310	COG2995	paraquat-inducible protein a
GPY30_RS07315	COG1132	(ABC) transporter
GPY30_RS07320	COG1956	GAF domain-containing protein
GPY30_RS07340	COG0308	aminopeptidase N
GPY30_RS07355	COG0167	dihydroorotate dehydrogenase activity
GPY30_RS07365	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY30_RS07365	COG0116	Belongs to the methyltransferase superfamily
GPY30_RS07395	COG1067	ATP-dependent peptidase activity
GPY30_RS07400	COG3120	sequence-specific DNA binding
GPY30_RS07475	COG0784	Response regulator, receiver
GPY30_RS07475	COG2205	protein histidine kinase activity
GPY30_RS07490	COG3278	Belongs to the heme-copper respiratory oxidase family
GPY30_RS07505	COG2010	Cytochrome c
GPY30_RS07515	COG2217	Heavy metal translocating P-type atpase
GPY30_RS07530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY30_RS07535	COG0589	response to stress
GPY30_RS07550	COG2992	FlgJ-related protein
GPY30_RS07565	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPY30_RS07570	COG1177	transmembrane transport
GPY30_RS07575	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY30_RS07580	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY30_RS07590	COG0004	ammonium transporteR
GPY30_RS07595	COG0488	(ABC) transporter
GPY30_RS07600	COG0746	molybdenum cofactor guanylyltransferase activity
GPY30_RS07605	COG1763	Mo-molybdopterin cofactor biosynthetic process
GPY30_RS07630	COG0840	transmembrane signaling receptor activity
GPY30_RS07635	COG0791	NLP P60 protein
GPY30_RS07645	COG3706	GGDEF domain
GPY30_RS07665	COG0307	riboflavin synthase, alpha
GPY30_RS07670	COG0534	Mate efflux family protein
GPY30_RS07680	COG1793	dna ligase
GPY30_RS07700	COG0584	glycerophosphoryl diester phosphodiesterase
GPY30_RS07705	COG1609	Transcriptional regulator
GPY30_RS07710	COG2723	6-phospho-beta-galactosidase activity
GPY30_RS07715	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GPY30_RS07725	COG1760	l-serine dehydratase
GPY30_RS07735	COG2814	Major facilitator Superfamily
GPY30_RS07745	COG1609	Transcriptional regulator
GPY30_RS07750	COG1942	4-Oxalocrotonate Tautomerase
GPY30_RS07780	COG3344	reverse transcriptase
GPY30_RS07875	COG2944	sequence-specific DNA binding
GPY30_RS07880	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
GPY30_RS08120	COG3041	Addiction module toxin RelE StbE family
GPY30_RS08310	COG1028	Short-chain dehydrogenase reductase Sdr
GPY30_RS08375	COG3344	reverse transcriptase
GPY30_RS08440	COG3738	Protein conserved in bacteria
GPY30_RS08470	COG1028	Short-chain dehydrogenase reductase Sdr
GPY30_RS08625	COG4628	conserved protein (DUF2132)
GPY30_RS08680	COG0625	glutathione transferase activity
GPY30_RS08780	COG4977	sequence-specific DNA binding
GPY30_RS08835	COG4115	mRNA cleavage
GPY30_RS08840	COG2161	toxin-antitoxin pair type II binding
GPY30_RS08875	COG0454	-acetyltransferase
GPY30_RS08935	COG0454	-acetyltransferase
GPY30_RS08960	COG1942	4-Oxalocrotonate Tautomerase
GPY30_RS09230	COG4387	Mu-like prophage protein GP36
GPY30_RS09240	COG4397	Mu-like prophage major head subunit gpT
GPY30_RS09250	COG4388	Caudovirus prohead serine protease
GPY30_RS09270	COG4383	Mu-like prophage protein gp29
GPY30_RS09275	COG4373	Mu-like prophage FluMu protein gp28
GPY30_RS09285	COG0640	Transcriptional regulator
GPY30_RS09315	COG5566	PFAM Mor transcription activator
GPY30_RS09400	COG2842	Transposition protein
GPY30_RS09405	COG2801	Transposase and inactivated derivatives
GPY30_RS09410	COG3423	Transcriptional regulator
GPY30_RS09435	COG0625	glutathione transferase activity
GPY30_RS09650	COG4628	conserved protein (DUF2132)
GPY30_RS09855	COG0653	protein targeting
GPY30_RS10220	COG0454	-acetyltransferase
GPY30_RS10285	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPY30_RS10290	COG0363	glucosamine-6-phosphate deaminase activity
GPY30_RS10295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPY30_RS10300	COG4565	transcriptional regulatory protein
GPY30_RS10305	COG3290	protein histidine kinase activity
GPY30_RS10320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY30_RS10340	COG1115	amino acid carrier protein
GPY30_RS10345	COG1280	lysine exporter protein (LysE YggA)
GPY30_RS10350	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GPY30_RS10405	COG0010	Belongs to the arginase family
GPY30_RS10435	COG0277	FAD linked oxidase domain protein
GPY30_RS10435	COG0247	lactate metabolic process
GPY30_RS10450	COG2885	chlorophyll binding
GPY30_RS10490	COG1643	Atp-dependent helicase
GPY30_RS10500	COG2949	membrane
GPY30_RS10505	COG0471	metal ion transport
GPY30_RS10510	COG3706	GGDEF domain
GPY30_RS10510	COG0745	RESPONSE REGULATOR receiver
GPY30_RS10530	COG0492	ferredoxin-NADP+ reductase activity
GPY30_RS10535	COG4988	ABC transporter
GPY30_RS10540	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GPY30_RS10555	COG1120	ATPase activity
GPY30_RS10565	COG1132	(ABC) transporter
GPY30_RS10570	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPY30_RS10580	COG5002	protein histidine kinase activity
GPY30_RS10580	COG5002	protein histidine kinase activity
GPY30_RS10595	COG3070	regulator of competence-specific genes
GPY30_RS10615	COG0076	glutamate decarboxylase activity
GPY30_RS10620	COG1737	Transcriptional regulator
GPY30_RS10625	COG1012	belongs to the aldehyde dehydrogenase family
GPY30_RS10625	COG1454	alcohol dehydrogenase
GPY30_RS10630	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY30_RS10635	COG2985	domain, Protein
GPY30_RS10635	COG3273	potassium ion transport
GPY30_RS10675	COG0534	Mate efflux family protein
GPY30_RS10680	COG0702	epimerase
GPY30_RS10690	COG2814	Major facilitator Superfamily
GPY30_RS10700	COG1061	Type III restriction enzyme res subunit
GPY30_RS10715	COG5002	protein histidine kinase activity
GPY30_RS10725	COG0737	Belongs to the 5'-nucleotidase family
GPY30_RS10735	COG3313	Fe-S protein
GPY30_RS10745	COG4134	Bacterial extracellular solute-binding protein
GPY30_RS10750	COG4135	transport system, permease component
GPY30_RS10755	COG4136	ATPase activity
GPY30_RS10760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPY30_RS10765	COG3604	Transcriptional regulator
GPY30_RS10770	COG1151	hydroxylamine reductase activity
GPY30_RS10780	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY30_RS10780	COG0116	Belongs to the methyltransferase superfamily
GPY30_RS10785	COG0564	pseudouridine synthase activity
GPY30_RS10790	COG0733	neurotransmitter:sodium symporter activity
GPY30_RS10800	COG0626	cystathionine gamma-synthase activity
GPY30_RS10805	COG2818	Glycosylase
GPY30_RS10820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY30_RS10825	COG1983	PspC domain protein
GPY30_RS10835	COG1842	Phage shock protein A
GPY30_RS10840	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GPY30_RS10850	COG4168	peptide transport system, permease
GPY30_RS10855	COG4171	peptide transport system, permease
GPY30_RS10865	COG4172	Belongs to the ABC transporter superfamily
GPY30_RS10880	COG1227	inorganic diphosphatase activity
GPY30_RS10900	COG3005	denitrification pathway
GPY30_RS10905	COG4459	periplasmic nitrate reductase
GPY30_RS10910	COG2116	formate transmembrane transporter activity
GPY30_RS10930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY30_RS10935	COG1435	thymidine kinase activity
GPY30_RS10945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPY30_RS10950	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY30_RS10955	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY30_RS10960	COG3012	SEC-C Motif Domain Protein
GPY30_RS10965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GPY30_RS10965	COG0140	phosphoribosyl-ATP diphosphatase activity
GPY30_RS10975	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPY30_RS10980	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPY30_RS10985	COG0131	Imidazoleglycerol-phosphate dehydratase
GPY30_RS10985	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPY30_RS10990	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPY30_RS10995	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPY30_RS11005	COG1757	Na H antiporter
GPY30_RS11010	COG2916	Histone family protein nucleoid-structuring protein H-NS
GPY30_RS11015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY30_RS11025	COG0482	sulfurtransferase activity
GPY30_RS11035	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPY30_RS11045	COG2268	Band 7 protein
GPY30_RS11055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GPY30_RS11070	COG1028	Short-chain dehydrogenase reductase Sdr
GPY30_RS11080	COG0501	Belongs to the peptidase M48B family
GPY30_RS11090	COG2226	methyltransferase
GPY30_RS11095	COG0156	8-amino-7-oxononanoate synthase activity
GPY30_RS11130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GPY30_RS11145	COG1522	sequence-specific DNA binding
GPY30_RS11160	COG0583	DNA-binding transcription factor activity
GPY30_RS11185	COG4608	Belongs to the ABC transporter superfamily
GPY30_RS11190	COG0444	Belongs to the ABC transporter superfamily
GPY30_RS11195	COG4166	transmembrane transport
GPY30_RS11200	COG4239	(ABC) transporter, permease
GPY30_RS11205	COG0601	transmembrane transport
GPY30_RS11215	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GPY30_RS11220	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GPY30_RS11230	COG0539	negative regulation of cytoplasmic translation
GPY30_RS11240	COG0616	signal peptide processing
GPY30_RS11245	COG1028	Short-chain dehydrogenase reductase Sdr
GPY30_RS11255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPY30_RS11260	COG0587	DNA-directed DNA polymerase activity
GPY30_RS11265	COG0835	chemotaxis
GPY30_RS11265	COG0784	Response regulator, receiver
GPY30_RS11270	COG1940	carbohydrate kinase activity
GPY30_RS11275	COG0469	pyruvate kinase activity
GPY30_RS11305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY30_RS11305	COG1263	PTS System
GPY30_RS11310	COG0084	hydrolase, TatD family'
GPY30_RS11325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPY30_RS11355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY30_RS11370	COG1399	metal-binding, possibly nucleic acid-binding protein
GPY30_RS11375	COG0424	maF-like protein
GPY30_RS11385	COG1530	ribonuclease E activity
GPY30_RS11390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPY30_RS11395	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GPY30_RS11405	COG0572	uridine kinase
GPY30_RS11410	COG0489	protein tyrosine kinase activity
GPY30_RS11440	COG0653	protein targeting
GPY30_RS11450	COG0366	Alpha amylase catalytic
GPY30_RS11460	COG4120	Belongs to the binding-protein-dependent transport system permease family
GPY30_RS11470	COG3092	negative regulation of chromosome organization
GPY30_RS11475	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPY30_RS11480	COG0280	phosphate acetyltransferase
GPY30_RS11480	COG0857	belongs to the CobB CobQ family
GPY30_RS11485	COG3174	membrane
GPY30_RS11490	COG0435	Glutathione S-transferase
GPY30_RS11500	COG0444	Belongs to the ABC transporter superfamily
GPY30_RS11505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY30_RS11510	COG0601	transmembrane transport
GPY30_RS11520	COG0314	molybdopterin synthase activity
GPY30_RS11525	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPY30_RS11530	COG0315	cyclic pyranopterin monophosphate synthase activity
GPY30_RS11535	COG0521	Mo-molybdopterin cofactor biosynthetic process
GPY30_RS11545	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GPY30_RS11570	COG2814	Major facilitator Superfamily
GPY30_RS11575	COG1566	PFAM secretion protein HlyD family protein
GPY30_RS11585	COG4657	Part of a membrane complex involved in electron transport
GPY30_RS11595	COG4656	Part of a membrane complex involved in electron transport
GPY30_RS11605	COG4659	FMN binding
GPY30_RS11615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPY30_RS11620	COG0346	lactoylglutathione lyase activity
GPY30_RS11630	COG2885	chlorophyll binding
GPY30_RS11635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPY30_RS11640	COG2056	Na+-H+ antiporter family
GPY30_RS11650	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GPY30_RS11665	COG1028	Short-chain dehydrogenase reductase Sdr
GPY30_RS11670	COG1012	belongs to the aldehyde dehydrogenase family
GPY30_RS11670	COG1454	alcohol dehydrogenase
GPY30_RS11675	COG2095	MarC family integral membrane protein
GPY30_RS11680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY30_RS11685	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPY30_RS11690	COG1757	Na H antiporter
GPY30_RS11700	COG3385	transposase activity
GPY30_RS11705	COG3081	Nucleoid-associated protein
GPY30_RS11715	COG3083	sulfuric ester hydrolase activity
GPY30_RS11720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY30_RS11735	COG0123	including yeast histone deacetylase and acetoin utilization protein
GPY30_RS11740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY30_RS11745	COG0778	Nitroreductase
GPY30_RS11755	COG0616	signal peptide processing
GPY30_RS11760	COG0252	asparaginase activity
GPY30_RS11765	COG3139	Protein of unknown function (DUF1315)
GPY30_RS11780	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY30_RS11800	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPY30_RS11815	COG2873	o-acetylhomoserine
GPY30_RS11820	COG1285	pathogenesis
GPY30_RS11825	COG2239	Acts as a magnesium transporter
GPY30_RS11865	COG2226	methyltransferase
GPY30_RS11880	COG1785	Belongs to the alkaline phosphatase family
GPY30_RS11885	COG2983	Belongs to the UPF0260 family
GPY30_RS11895	COG0745	RESPONSE REGULATOR receiver
GPY30_RS11900	COG2205	protein histidine kinase activity
GPY30_RS11920	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPY30_RS11935	COG2832	Protein of unknown function (DUF454)
GPY30_RS11945	COG0745	RESPONSE REGULATOR receiver
GPY30_RS11950	COG0583	DNA-binding transcription factor activity
GPY30_RS11955	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPY30_RS11960	COG1286	toxin biosynthetic process
GPY30_RS11965	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GPY30_RS11970	COG0285	dihydrofolate synthase activity
GPY30_RS11990	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPY30_RS12000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPY30_RS12020	COG3101	peptidyl-lysine hydroxylation
GPY30_RS12025	COG2860	membrane
GPY30_RS12030	COG1028	Short-chain dehydrogenase reductase Sdr
GPY30_RS12035	COG0583	DNA-binding transcription factor activity
GPY30_RS12040	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPY30_RS12045	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY30_RS12055	COG2062	phosphohistidine phosphatase, SixA
GPY30_RS12060	COG1025	Belongs to the peptidase M16 family
GPY30_RS12065	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPY30_RS12065	COG1024	Enoyl-CoA hydratase
GPY30_RS12070	COG0183	Belongs to the thiolase family
GPY30_RS12075	COG1595	DNA-templated transcription, initiation
GPY30_RS12085	COG2067	long-chain fatty acid transport protein
GPY30_RS12095	COG2853	Lipoprotein
GPY30_RS12110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY30_RS12125	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY30_RS12135	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY30_RS12140	COG4133	protoheme IX ABC transporter activity
GPY30_RS12150	COG0835	chemotaxis
GPY30_RS12160	COG1192	Involved in chromosome partitioning
GPY30_RS12165	COG2201	protein-glutamate methylesterase activity
GPY30_RS12170	COG0643	Histidine kinase
GPY30_RS12170	COG2198	Histidine kinase
GPY30_RS12175	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GPY30_RS12190	COG0455	bacterial-type flagellum organization
GPY30_RS12210	COG1684	flagellar biosynthetic protein fliR
GPY30_RS12215	COG1987	bacterial-type flagellum assembly
GPY30_RS12265	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY30_RS12275	COG1677	Flagellar hook-basal body complex protein FliE
GPY30_RS12280	COG2204	response regulator
GPY30_RS12285	COG4191	Histidine kinase
GPY30_RS12290	COG2204	response regulator
GPY30_RS12295	COG1516	flagellar protein fliS
GPY30_RS12305	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPY30_RS12310	COG1334	flagellar protein FlaG
GPY30_RS12315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY30_RS12320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY30_RS12325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY30_RS12330	COG2837	iron assimilation
GPY30_RS12360	COG1393	Belongs to the ArsC family
GPY30_RS12365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY30_RS12390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPY30_RS12395	COG2716	regulation of RNA biosynthetic process
GPY30_RS12400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPY30_RS12415	COG4783	chaperone-mediated protein folding
GPY30_RS12420	COG1393	Belongs to the ArsC family
GPY30_RS12440	COG2233	PERMEase
GPY30_RS12445	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPY30_RS12455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPY30_RS12460	COG0121	glutamine amidotransferase
GPY30_RS12470	COG1960	acyl-CoA dehydrogenase activity
GPY30_RS12490	COG2226	methyltransferase
GPY30_RS12495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY30_RS12500	COG1388	LysM domain
GPY30_RS12500	COG0741	lytic transglycosylase activity
GPY30_RS12510	COG3021	interspecies interaction between organisms
GPY30_RS12515	COG0347	Belongs to the P(II) protein family
GPY30_RS12535	COG0587	DNA-directed DNA polymerase activity
GPY30_RS12545	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY30_RS12560	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY30_RS12565	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GPY30_RS12575	COG0750	zinc metalloprotease
GPY30_RS12585	COG0575	Belongs to the CDS family
GPY30_RS12595	COG0233	cytoplasmic translational termination
GPY30_RS12615	COG0024	Methionine aminopeptidase
GPY30_RS12620	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GPY30_RS12635	COG3098	single-species biofilm formation
GPY30_RS12665	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY30_RS12670	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GPY30_RS12680	COG1720	tRNA m6t6A37 methyltransferase activity
GPY30_RS12710	COG3469	chitinase activity
GPY30_RS12745	COG0753	catalase activity
GPY30_RS12775	COG0583	DNA-binding transcription factor activity
GPY30_RS12795	COG3240	lipase activity
GPY30_RS12930	COG0514	ATP-dependent DNA helicase (RecQ)
GPY30_RS12950	COG1477	protein flavinylation
GPY30_RS12955	COG2871	sodium ion transport
GPY30_RS12960	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY30_RS12975	COG1805	sodium ion transport
GPY30_RS12980	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY30_RS12985	COG0271	Belongs to the BolA IbaG family
GPY30_RS13000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPY30_RS13015	COG1595	DNA-templated transcription, initiation
GPY30_RS13030	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPY30_RS13040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPY30_RS13045	COG2166	iron-sulfur cluster assembly
GPY30_RS13050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GPY30_RS13055	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GPY30_RS13080	COG1074	ATP-dependent DNA helicase activity
GPY30_RS13085	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GPY30_RS13090	COG3083	sulfuric ester hydrolase activity
GPY30_RS13105	COG3141	response to X-ray
GPY30_RS13110	COG2171	N-acyltransferase activity
GPY30_RS13115	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPY30_RS13125	COG1349	DNA-binding transcription factor activity
GPY30_RS13130	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPY30_RS13140	COG0456	acetyltransferase
GPY30_RS13160	COG0840	transmembrane signaling receptor activity
GPY30_RS13165	COG0583	DNA-binding transcription factor activity
GPY30_RS13170	COG2059	Chromate
GPY30_RS13185	COG0583	DNA-binding transcription factor activity
GPY30_RS13190	COG3344	reverse transcriptase
GPY30_RS13195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPY30_RS13200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPY30_RS13210	COG0560	Phosphoserine phosphatase
GPY30_RS13235	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPY30_RS13240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY30_RS13245	COG0084	hydrolase, TatD family'
GPY30_RS13275	COG3153	acetyltransferase
GPY30_RS13300	COG0534	Mate efflux family protein
GPY30_RS13310	COG4785	May be involved in cell division
GPY30_RS13325	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPY30_RS13340	COG0195	Participates in both transcription termination and antitermination
GPY30_RS13345	COG0779	Required for maturation of 30S ribosomal subunits
GPY30_RS13360	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY30_RS13365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY30_RS13370	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPY30_RS13375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPY30_RS13380	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GPY30_RS13385	COG1534	Rna-binding protein
GPY30_RS13390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY30_RS13395	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPY30_RS13400	COG2027	D-alanyl-D-alanine carboxypeptidase
GPY30_RS13410	COG0739	heme binding
GPY30_RS13430	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GPY30_RS13435	COG0628	permease
GPY30_RS13450	COG0747	negative chemotaxis
GPY30_RS13460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY30_RS13465	COG0444	Belongs to the ABC transporter superfamily
GPY30_RS13470	COG4608	Belongs to the ABC transporter superfamily
GPY30_RS13495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY30_RS13500	COG3842	ATPase activity
GPY30_RS13510	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY30_RS13515	COG0004	ammonium transporteR
GPY30_RS13520	COG0347	Belongs to the P(II) protein family
GPY30_RS13525	COG4771	TonB-dependent receptor
GPY30_RS13535	COG0745	RESPONSE REGULATOR receiver
GPY30_RS13590	COG1929	Belongs to the glycerate kinase type-1 family
GPY30_RS13600	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPY30_RS13605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPY30_RS13610	COG1643	Atp-dependent helicase
GPY30_RS13620	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY30_RS13625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY30_RS13635	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY30_RS13655	COG1131	(ABC) transporter
GPY30_RS13660	COG0659	secondary active sulfate transmembrane transporter activity
GPY30_RS13665	COG0288	reversible hydration of carbon dioxide
GPY30_RS13680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY30_RS13685	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY30_RS13690	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GPY30_RS13695	COG2186	Transcriptional regulator
GPY30_RS13715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY30_RS13720	COG1459	type II secretion system
GPY30_RS13730	COG0237	dephospho-CoA kinase activity
GPY30_RS13745	COG0335	large ribosomal subunit rRNA binding
GPY30_RS13765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPY30_RS13770	COG4137	Cytochrome C assembly protein
GPY30_RS13775	COG4536	flavin adenine dinucleotide binding
GPY30_RS13795	COG0612	Peptidase, M16
GPY30_RS13800	COG1238	metal cluster binding
GPY30_RS13805	COG1063	alcohol dehydrogenase
GPY30_RS13810	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPY30_RS13815	COG5016	pyruvate
GPY30_RS13815	COG0511	ligase activity, forming carbon-carbon bonds
GPY30_RS13870	COG0527	aspartate kinase activity
GPY30_RS13875	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPY30_RS13890	COG1546	Belongs to the CinA family
GPY30_RS13895	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPY30_RS13900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPY30_RS13930	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPY30_RS13940	COG0148	phosphopyruvate hydratase activity
GPY30_RS13950	COG3956	TIGRFAM MazG family protein
GPY30_RS13955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY30_RS13985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPY30_RS13995	COG0681	Belongs to the peptidase S26 family
GPY30_RS14005	COG3086	response to oxidative stress
GPY30_RS14010	COG3026	antisigma factor binding
GPY30_RS14020	COG1595	DNA-templated transcription, initiation
GPY30_RS14025	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GPY30_RS14040	COG0354	folic acid binding
GPY30_RS14055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY30_RS14060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY30_RS14065	COG3079	Belongs to the UPF0149 family
GPY30_RS14070	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPY30_RS14090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY30_RS14110	COG0668	transmembrane transport
GPY30_RS14115	COG0191	fructose-bisphosphate aldolase activity
GPY30_RS14125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY30_RS14145	COG2356	endonuclease I
GPY30_RS14155	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GPY30_RS14170	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPY30_RS14185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPY30_RS14190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPY30_RS14195	COG0762	integral membrane protein
GPY30_RS14215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY30_RS14235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GPY30_RS14250	COG0741	lytic transglycosylase activity
GPY30_RS14270	COG0840	transmembrane signaling receptor activity
GPY30_RS14310	COG3344	reverse transcriptase
GPY30_RS14435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPY30_RS14450	COG0795	lipopolysaccharide-transporting ATPase activity
GPY30_RS14455	COG0795	lipopolysaccharide-transporting ATPase activity
GPY30_RS14465	COG2927	DNA polymerase III (CHI subunit)
GPY30_RS14480	COG4269	membrane
GPY30_RS14490	COG0456	acetyltransferase
GPY30_RS14520	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GPY30_RS14525	COG0251	oxidation-reduction process
GPY30_RS14530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY30_RS14545	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GPY30_RS14550	COG0312	modulator of DNA gyrase
GPY30_RS14560	COG3164	Protein of unknown function
GPY30_RS14565	COG1530	ribonuclease E activity
GPY30_RS14575	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GPY30_RS14580	COG1792	Involved in formation and maintenance of cell shape
GPY30_RS14585	COG1077	Cell shape determining protein MreB Mrl
GPY30_RS14630	COG1459	type II secretion system
GPY30_RS14635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY30_RS14645	COG3267	Type II secretory pathway component ExeA
GPY30_RS14645	COG3409	Peptidoglycan-binding domain 1 protein
GPY30_RS14670	COG2200	EAL domain
GPY30_RS14670	COG2199	diguanylate cyclase activity
GPY30_RS14675	COG0629	single-stranded DNA binding
GPY30_RS14695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPY30_RS14705	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPY30_RS14710	COG0527	aspartate kinase activity
GPY30_RS14715	COG0646	methionine synthase
GPY30_RS14715	COG1410	methionine synthase
GPY30_RS14725	COG0204	Acyl-transferase
GPY30_RS14730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPY30_RS14735	COG5007	Belongs to the BolA IbaG family
GPY30_RS14745	COG2854	intermembrane phospholipid transfer
GPY30_RS14750	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPY30_RS14755	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GPY30_RS14760	COG1127	ABC transporter
GPY30_RS14770	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GPY30_RS14770	COG0517	IMP dehydrogenase activity
GPY30_RS14775	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GPY30_RS14790	COG1137	ATPase activity
GPY30_RS14800	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY30_RS14805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY30_RS14810	COG1660	Displays ATPase and GTPase activities
GPY30_RS14815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY30_RS14820	COG2239	Acts as a magnesium transporter
GPY30_RS14825	COG0312	modulator of DNA gyrase
GPY30_RS14830	COG3028	Belongs to the UPF0307 family
GPY30_RS14840	COG1178	ABC-type Fe3 transport system permease component
GPY30_RS14845	COG4143	(ABC) transporter
GPY30_RS14850	COG0163	prenyltransferase activity
GPY30_RS14855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPY30_RS14870	COG2105	PFAM AIG2 family protein
GPY30_RS14895	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GPY30_RS14910	COG1136	(ABC) transporter
GPY30_RS14910	COG0577	efflux transmembrane transporter activity
GPY30_RS14935	COG0471	metal ion transport
GPY30_RS14935	COG3273	potassium ion transport
GPY30_RS14940	COG2895	sulfate adenylyltransferase (ATP) activity
GPY30_RS14950	COG1648	precorrin-2 dehydrogenase activity
GPY30_RS14950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPY30_RS14955	COG0737	Belongs to the 5'-nucleotidase family
GPY30_RS14965	COG2153	protein acetylation
GPY30_RS14970	COG0697	spore germination
GPY30_RS14980	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY30_RS15000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPY30_RS15015	COG0201	protein transport
GPY30_RS15025	COG1841	ribosomal large subunit assembly
GPY30_RS15035	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPY30_RS15045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPY30_RS15080	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPY30_RS15090	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPY30_RS15095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPY30_RS15110	COG0088	Forms part of the polypeptide exit tunnel
GPY30_RS15115	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPY30_RS15130	COG2906	2 iron, 2 sulfur cluster binding
GPY30_RS15140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPY30_RS15160	COG2923	Belongs to the DsrF TusC family
GPY30_RS15165	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GPY30_RS15170	COG2964	Protein conserved in bacteria
GPY30_RS15175	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY30_RS15195	COG1047	Peptidyl-prolyl cis-trans
GPY30_RS15210	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPY30_RS15215	COG0488	(ABC) transporter
GPY30_RS15225	COG0429	hydrolase of the alpha beta-hydrolase fold
GPY30_RS15235	COG3954	Phosphoribulokinase
GPY30_RS15240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY30_RS15250	COG1012	belongs to the aldehyde dehydrogenase family
GPY30_RS15260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPY30_RS15270	COG2356	endonuclease I
GPY30_RS15290	COG0180	Tryptophanyl-tRNA synthetase
GPY30_RS15305	COG0557	exoribonuclease II activity
GPY30_RS15320	COG3344	reverse transcriptase
GPY30_RS15325	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GPY30_RS15330	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPY30_RS15335	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GPY30_RS15340	COG0330	HflC and HflK could
GPY30_RS15345	COG0330	HflC and HflK could
GPY30_RS15350	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPY30_RS15365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPY30_RS15370	COG0860	N-Acetylmuramoyl-L-alanine amidase
GPY30_RS15375	COG0802	atpase or kinase
GPY30_RS15380	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPY30_RS15480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY30_RS15495	COG1045	serine acetyltransferase
GPY30_RS15500	COG4942	peptidase
GPY30_RS15525	COG1053	succinate dehydrogenase
GPY30_RS15530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPY30_RS15535	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPY30_RS15555	COG1509	lysine 2,3-aminomutase activity
GPY30_RS15580	COG0534	Mate efflux family protein
GPY30_RS15600	COG0745	RESPONSE REGULATOR receiver
GPY30_RS15605	COG2205	protein histidine kinase activity
GPY30_RS15610	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GPY30_RS15620	COG1027	Aspartate ammonia-lyase
GPY30_RS15625	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPY30_RS15630	COG4232	protein-disulfide reductase activity
GPY30_RS15640	COG3263	regulation of cellular component size
GPY30_RS15650	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY30_RS15665	COG2198	Histidine kinase
GPY30_RS15665	COG2205	protein histidine kinase activity
GPY30_RS15665	COG0784	Response regulator, receiver
GPY30_RS15670	COG2814	Major facilitator Superfamily
GPY30_RS15685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY30_RS15690	COG1902	pentaerythritol trinitrate reductase activity
GPY30_RS15705	COG0511	ligase activity, forming carbon-carbon bonds
GPY30_RS15710	COG0439	Biotin carboxylase
GPY30_RS15725	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GPY30_RS15735	COG0840	transmembrane signaling receptor activity
GPY30_RS15740	COG0789	Transcriptional regulator
GPY30_RS15750	COG0138	bifunctional purine biosynthesis protein purh
GPY30_RS15760	COG3344	reverse transcriptase
GPY30_RS15775	COG1253	flavin adenine dinucleotide binding
GPY30_RS15780	COG3068	Protein conserved in bacteria
GPY30_RS15790	COG1573	uracil-dna glycosylase
GPY30_RS15825	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPY30_RS15840	COG0250	Participates in transcription elongation, termination and antitermination
GPY30_RS15845	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY30_RS15880	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GPY30_RS15880	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GPY30_RS15895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPY30_RS15900	COG3335	DDE superfamily endonuclease
GPY30_RS15950	COG0724	RNA recognition motif
GPY30_RS15970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY30_RS16000	COG1518	maintenance of DNA repeat elements
GPY30_RS16035	COG2937	Belongs to the GPAT DAPAT family
GPY30_RS16040	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GPY30_RS16050	COG1580	Controls the rotational direction of flagella during chemotaxis
GPY30_RS16055	COG0705	Rhomboid family
GPY30_RS16070	COG2177	Part of the ABC transporter FtsEX involved in
GPY30_RS16075	COG2884	Cell division ATP-binding protein ftsE
GPY30_RS16080	COG0552	protein localization to endoplasmic reticulum
GPY30_RS16085	COG0742	ribosomal rna small subunit methyltransferase
GPY30_RS16095	COG2095	MarC family integral membrane protein
GPY30_RS16115	COG3274	enterobacterial common antigen metabolic process
GPY30_RS16120	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY30_RS16125	COG1280	lysine exporter protein (LysE YggA)
GPY30_RS16130	COG2267	carboxylic ester hydrolase activity
GPY30_RS16145	COG1881	PFAM PEBP family protein
GPY30_RS16150	COG2207	Transcriptional regulator
GPY30_RS16160	COG3046	protein related to deoxyribodipyrimidine photolyase
GPY30_RS16180	COG0745	RESPONSE REGULATOR receiver
GPY30_RS16185	COG2205	protein histidine kinase activity
GPY30_RS16190	COG1653	transport
GPY30_RS16195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY30_RS16200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPY30_RS16215	COG1342	Belongs to the UPF0251 family
GPY30_RS16240	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPY30_RS16245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY30_RS16255	COG0583	DNA-binding transcription factor activity
GPY30_RS16280	COG3033	Beta-eliminating lyase
GPY30_RS16300	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPY30_RS16305	COG0625	glutathione transferase activity
GPY30_RS16325	COG3047	cAMP biosynthetic process
GPY30_RS16330	COG0579	oxidoreductase
GPY30_RS16355	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GPY30_RS16365	COG0583	DNA-binding transcription factor activity
GPY30_RS16370	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPY30_RS16375	COG2814	Major facilitator Superfamily
GPY30_RS16380	COG0583	DNA-binding transcription factor activity
GPY30_RS16390	COG1294	oxidase, subunit
GPY30_RS16395	COG0625	glutathione transferase activity
GPY30_RS16400	COG0583	DNA-binding transcription factor activity
GPY30_RS16405	COG0640	Transcriptional regulator
GPY30_RS16410	COG0798	PFAM Bile acid sodium symporter
GPY30_RS16420	COG0544	peptidyl-prolyl cis-trans isomerase activity
GPY30_RS16425	COG0697	spore germination
GPY30_RS16430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY30_RS16430	COG1263	PTS System
GPY30_RS16440	COG1621	beta-fructofuranosidase activity
GPY30_RS16445	COG4251	negative regulation of phosphorylation
GPY30_RS16445	COG2203	Gaf domain
GPY30_RS16445	COG5001	Diguanylate cyclase
GPY30_RS16445	COG3706	GGDEF domain
GPY30_RS16450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY30_RS16460	COG2207	Transcriptional regulator
GPY30_RS16460	COG3708	Transcriptional regulator
GPY30_RS16490	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GPY30_RS16510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPY30_RS16520	COG0583	DNA-binding transcription factor activity
GPY30_RS16530	COG2149	membrane
GPY30_RS16535	COG0641	radical SAM
GPY30_RS16545	COG2211	Major facilitator Superfamily
GPY30_RS16560	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GPY30_RS16565	COG1640	4-alpha-glucanotransferase
GPY30_RS16570	COG0058	SHG alpha-glucan phosphorylase activity
GPY30_RS16575	COG2909	trisaccharide binding
GPY30_RS16590	COG3842	ATPase activity
GPY30_RS16600	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY30_RS16610	COG2182	Extracellular solute-binding protein
GPY30_RS16615	COG1175	transmembrane transport
GPY30_RS16620	COG3833	ABC-type maltose transport systems, permease component
GPY30_RS16650	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GPY30_RS16655	COG1162	GTPase activity
GPY30_RS16665	COG1999	signal sequence binding
GPY30_RS16685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY30_RS16745	COG0215	cysteine-tRNA ligase activity
GPY30_RS16755	COG1444	tRNA N-acetyltransferase activity
GPY30_RS16775	COG3227	Zinc metalloprotease (Elastase)
GPY30_RS16795	COG0217	transcriptional regulatory protein
GPY30_RS16825	COG3275	phosphorelay sensor kinase activity
GPY30_RS16840	COG0786	glutamate:sodium symporter activity
GPY30_RS16845	COG0786	glutamate:sodium symporter activity
GPY30_RS16870	COG0189	ligase activity
GPY30_RS16890	COG2169	Transcriptional regulator
GPY30_RS16890	COG1917	Cupin 2, conserved barrel domain protein
GPY30_RS16900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPY30_RS16940	COG1741	Belongs to the pirin family
GPY30_RS16950	COG5001	Diguanylate cyclase
GPY30_RS17000	COG1132	(ABC) transporter
GPY30_RS17010	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPY30_RS17015	COG3457	Alanine racemase
GPY30_RS17030	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GPY30_RS17040	COG2188	Transcriptional regulator
GPY30_RS17045	COG0513	Belongs to the DEAD box helicase family
GPY30_RS17050	COG1022	Amp-dependent synthetase and ligase
GPY30_RS17070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GPY30_RS17075	COG0537	adenosine 5'-monophosphoramidase activity
GPY30_RS17090	COG2084	Dehydrogenase
GPY30_RS17105	COG0028	Belongs to the TPP enzyme family
GPY30_RS17120	COG1979	alcohol dehydrogenase
GPY30_RS17155	COG0840	transmembrane signaling receptor activity
GPY30_RS17185	COG0745	RESPONSE REGULATOR receiver
GPY30_RS17185	COG3706	GGDEF domain
GPY30_RS17190	COG0784	Response regulator, receiver
GPY30_RS17190	COG2205	protein histidine kinase activity
GPY30_RS17190	COG5002	protein histidine kinase activity
GPY30_RS17215	COG0513	Belongs to the DEAD box helicase family
GPY30_RS17265	COG0745	RESPONSE REGULATOR receiver
GPY30_RS17270	COG0642	Histidine kinase
GPY30_RS17275	COG3706	GGDEF domain
GPY30_RS17275	COG0745	RESPONSE REGULATOR receiver
GPY30_RS17290	COG0564	pseudouridine synthase activity
GPY30_RS17300	COG3220	belongs to the UPF0276 family
GPY30_RS17320	COG2205	protein histidine kinase activity
GPY30_RS17320	COG2198	Histidine kinase
GPY30_RS17320	COG0784	Response regulator, receiver
GPY30_RS17325	COG3437	response regulator, receiver
GPY30_RS17335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY30_RS17350	COG2184	nucleotidyltransferase activity
GPY30_RS17355	COG1741	Belongs to the pirin family
GPY30_RS17360	COG2259	Doxx family
GPY30_RS17370	COG0366	Alpha amylase catalytic
GPY30_RS17375	COG1349	DNA-binding transcription factor activity
GPY30_RS17380	COG0673	inositol 2-dehydrogenase activity
GPY30_RS17385	COG4702	Belongs to the UPF0303 family
GPY30_RS17390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPY30_RS17410	COG0625	glutathione transferase activity
GPY30_RS17425	COG3284	Transcriptional regulator
GPY30_RS17430	COG1012	belongs to the aldehyde dehydrogenase family
GPY30_RS17450	COG0513	Belongs to the DEAD box helicase family
GPY30_RS17490	COG0842	Transport permease protein
GPY30_RS17495	COG1131	(ABC) transporter
GPY30_RS17505	COG1737	Transcriptional regulator
GPY30_RS17515	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GPY30_RS17525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY30_RS17540	COG0251	oxidation-reduction process
GPY30_RS17545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY30_RS17550	COG2084	Dehydrogenase
GPY30_RS17560	COG2201	protein-glutamate methylesterase activity
GPY30_RS17565	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GPY30_RS17575	COG0835	chemotaxis
GPY30_RS17580	COG0840	transmembrane signaling receptor activity
GPY30_RS17585	COG0835	chemotaxis
GPY30_RS17590	COG2198	Histidine kinase
GPY30_RS17590	COG0643	Histidine kinase
GPY30_RS17620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY30_RS17630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY30_RS17670	COG0393	Putative heavy-metal-binding
GPY30_RS17685	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPY30_RS17705	COG2211	Major facilitator Superfamily
GPY30_RS17725	COG0156	8-amino-7-oxononanoate synthase activity
GPY30_RS17775	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GPY30_RS17800	COG1278	Cold shock
GPY30_RS17825	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPY30_RS17840	COG0753	catalase activity
GPY30_RS17870	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPY30_RS17875	COG0459	protein refolding
GPY30_RS17885	COG1737	Transcriptional regulator
GPY30_RS17925	COG0456	acetyltransferase
GPY30_RS17945	COG1917	Cupin 2, conserved barrel domain protein
GPY30_RS17945	COG4977	sequence-specific DNA binding
GPY30_RS17950	COG1335	isochorismatase
GPY30_RS17975	COG1301	dicarboxylic acid transport
GPY30_RS18005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY30_RS18020	COG2356	endonuclease I
GPY30_RS18030	COG1368	sulfuric ester hydrolase activity
GPY30_RS18035	COG2194	sulfuric ester hydrolase activity
GPY30_RS18040	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPY30_RS18045	COG2205	protein histidine kinase activity
GPY30_RS18050	COG0745	RESPONSE REGULATOR receiver
GPY30_RS18055	COG2910	NAD(P)H-binding
GPY30_RS18075	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY30_RS18080	COG4533	DNA binding
GPY30_RS18090	COG0561	phosphatase activity
GPY30_RS18105	COG0671	phosphoesterase, PA-phosphatase related
GPY30_RS18110	COG0351	phosphomethylpyrimidine kinase
GPY30_RS18180	COG0668	transmembrane transport
GPY30_RS18195	COG2239	Acts as a magnesium transporter
GPY30_RS18200	COG2207	Transcriptional regulator
GPY30_RS18210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY30_RS18215	COG0121	glutamine amidotransferase
GPY30_RS18220	COG0531	amino acid
GPY30_RS18250	COG0583	DNA-binding transcription factor activity
GPY30_RS18270	COG0534	Mate efflux family protein
GPY30_RS18290	COG2827	Endonuclease containing a URI domain
GPY30_RS18320	COG1522	sequence-specific DNA binding
GPY30_RS18335	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY30_RS18340	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY30_RS18350	COG0183	Belongs to the thiolase family
GPY30_RS18390	COG0243	molybdopterin cofactor binding
GPY30_RS18400	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPY30_RS18405	COG3850	Histidine kinase
GPY30_RS18410	COG2197	response regulator
GPY30_RS18420	COG2201	protein-glutamate methylesterase activity
GPY30_RS18430	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPY30_RS18430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GPY30_RS18460	COG1061	Type III restriction enzyme res subunit
GPY30_RS18520	COG1028	Short-chain dehydrogenase reductase Sdr
GPY30_RS18550	COG0583	DNA-binding transcription factor activity
GPY30_RS18555	COG0697	spore germination
GPY30_RS18585	COG2814	Major facilitator Superfamily
GPY30_RS18630	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GPY30_RS18655	COG0583	DNA-binding transcription factor activity
GPY30_RS18690	COG2267	carboxylic ester hydrolase activity
GPY30_RS18695	COG2378	regulation of single-species biofilm formation
GPY30_RS18725	COG0745	RESPONSE REGULATOR receiver
GPY30_RS18740	COG3083	sulfuric ester hydrolase activity
GPY30_RS18920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY30_RS18925	COG0697	spore germination
GPY30_RS18930	COG0784	Response regulator, receiver
GPY30_RS18930	COG3437	response regulator, receiver
GPY30_RS18940	COG3706	GGDEF domain
GPY30_RS18960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GPY30_RS18965	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPY30_RS18970	COG1845	cytochrome c oxidase, subunit III
GPY30_RS18975	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GPY30_RS18985	COG3344	reverse transcriptase
GPY30_RS18995	COG0456	acetyltransferase
GPY30_RS19000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPY30_RS19005	COG0662	Cupin 2, conserved barrel domain protein
GPY30_RS19010	COG0527	aspartate kinase activity
GPY30_RS19025	COG0640	Transcriptional regulator
GPY30_RS19030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY30_RS19050	COG0450	alkyl hydroperoxide reductase
GPY30_RS19065	COG1024	Enoyl-CoA hydratase
GPY30_RS19070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GPY30_RS19075	COG1960	acyl-CoA dehydrogenase activity
GPY30_RS19085	COG0183	Belongs to the thiolase family
GPY30_RS19095	COG1960	acyl-CoA dehydrogenase activity
GPY30_RS19100	COG1024	Enoyl-CoA hydratase
GPY30_RS19105	COG1024	Enoyl-CoA hydratase
GPY30_RS19115	COG1028	Short-chain dehydrogenase reductase Sdr
GPY30_RS19155	COG0583	DNA-binding transcription factor activity
GPY30_RS19205	COG2076	Multidrug Resistance protein
GPY30_RS19225	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GPY30_RS19225	COG0519	Catalyzes the synthesis of GMP from XMP
GPY30_RS19260	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPY30_RS19270	COG3437	response regulator, receiver
GPY30_RS19270	COG0784	Response regulator, receiver
GPY30_RS19275	COG4191	Histidine kinase
GPY30_RS19275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY30_RS19290	COG0443	Heat shock 70 kDa protein
GPY30_RS19315	COG3530	Putative quorum-sensing-regulated virulence factor
GPY30_RS19320	COG3226	Transcriptional regulator
GPY30_RS19330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY30_RS19345	COG1902	pentaerythritol trinitrate reductase activity
GPY30_RS19370	COG0523	cobalamin synthesis protein
GPY30_RS19375	COG0513	Belongs to the DEAD box helicase family
GPY30_RS19390	COG3706	GGDEF domain
GPY30_RS19400	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPY30_RS19415	COG0840	transmembrane signaling receptor activity
GPY30_RS19445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPY30_RS19465	COG5001	Diguanylate cyclase
GPY30_RS19470	COG2897	thiosulfate sulfurtransferase activity
GPY30_RS19475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY30_RS19510	COG4989	oxidoreductase activity
GPY30_RS19520	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY30_RS19540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY30_RS19545	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY30_RS19575	COG1278	Cold shock
GPY30_RS19580	COG3036	rescue of stalled ribosome
GPY30_RS19590	COG0840	transmembrane signaling receptor activity
GPY30_RS19605	COG0583	DNA-binding transcription factor activity
GPY30_RS19620	COG0747	negative chemotaxis
GPY30_RS19630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY30_RS19635	COG0444	Belongs to the ABC transporter superfamily
GPY30_RS19640	COG4608	Belongs to the ABC transporter superfamily
GPY30_RS19650	COG1609	Transcriptional regulator
GPY30_RS19690	COG4580	involved in the transport of maltose and maltodextrins
GPY30_RS19705	COG1472	Belongs to the glycosyl hydrolase 3 family
GPY30_RS19710	COG0534	Mate efflux family protein
GPY30_RS19715	COG0583	DNA-binding transcription factor activity
GPY30_RS19730	COG1609	Transcriptional regulator
GPY30_RS19740	COG1175	transmembrane transport
GPY30_RS19745	COG0395	ABC-type sugar transport system, permease component
GPY30_RS19750	COG2723	6-phospho-beta-galactosidase activity
GPY30_RS19755	COG3842	ATPase activity
GPY30_RS19760	COG3459	Glycosyltransferase 36 associated
GPY30_RS19765	COG2017	converts alpha-aldose to the beta-anomer
GPY30_RS19775	COG1609	Transcriptional regulator
GPY30_RS19800	COG0840	transmembrane signaling receptor activity
GPY30_RS19810	COG4139	cobalamin transport
GPY30_RS19815	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GPY30_RS19830	COG2130	NADP-dependent
GPY30_RS19835	COG1309	transcriptional regulator
GPY30_RS19840	COG0513	Belongs to the DEAD box helicase family
GPY30_RS19845	COG0589	response to stress
GPY30_RS19860	COG4607	ABC-type enterochelin transport system periplasmic component
GPY30_RS19865	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY30_RS19870	COG4605	iron ion homeostasis
GPY30_RS19875	COG4604	ABC transporter, ATP-binding protein
GPY30_RS19880	COG0789	Transcriptional regulator
GPY30_RS19885	COG2207	Transcriptional regulator
GPY30_RS19910	COG1289	transmembrane transporter activity
GPY30_RS19915	COG0210	DNA helicase
GPY30_RS19920	COG1803	Methylglyoxal synthase
GPY30_RS19925	COG1803	Methylglyoxal synthase
GPY30_RS19935	COG0784	Response regulator, receiver
GPY30_RS19935	COG2198	Histidine kinase
GPY30_RS19935	COG2205	protein histidine kinase activity
GPY30_RS19940	COG0322	excinuclease ABC activity
GPY30_RS19955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GPY30_RS19975	COG3069	C4-dicarboxylate transmembrane transporter activity
GPY30_RS20000	COG3788	relative of glutathione S-transferase, MAPEG superfamily
GPY30_RS20030	COG0583	DNA-binding transcription factor activity
GPY30_RS20050	COG4964	Belongs to the GSP D family
GPY30_RS20125	COG4166	transmembrane transport
GPY30_RS20140	COG4172	Belongs to the ABC transporter superfamily
GPY30_RS20225	COG0811	peptide transport
GPY30_RS20230	COG0811	peptide transport
GPY30_RS20235	COG0848	biopolymer transport protein
GPY30_RS20250	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPY30_RS20255	COG0840	transmembrane signaling receptor activity
GPY30_RS20285	COG3118	belongs to the thioredoxin family
GPY30_RS20290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY30_RS20335	COG1328	CTP reductase activity
GPY30_RS20340	COG0602	queuosine metabolic process
GPY30_RS20350	COG4067	protein conserved in archaea
GPY30_RS20350	COG0189	ligase activity
GPY30_RS20370	COG0725	ABC transporter, periplasmic molybdate-binding protein
GPY30_RS20375	COG4149	molybdate abc transporter
GPY30_RS20380	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GPY30_RS20385	COG0697	spore germination
GPY30_RS20390	COG1846	Transcriptional regulator
GPY30_RS20425	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GPY30_RS20435	COG0745	RESPONSE REGULATOR receiver
GPY30_RS20455	COG0023	Translation Initiation Factor
GPY30_RS20480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY30_RS20480	COG1042	CoA-binding domain protein
GPY30_RS20480	COG0045	succinate-CoA ligase (ADP-forming) activity
GPY30_RS20485	COG0583	DNA-binding transcription factor activity
GPY30_RS20490	COG4771	TonB-dependent receptor
GPY30_RS20510	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GPY30_RS20520	COG1984	allophanate hydrolase subunit 2
GPY30_RS20525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY30_RS20525	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GPY30_RS20535	COG4181	ATPase activity
GPY30_RS20545	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPY30_RS20550	COG5001	Diguanylate cyclase
GPY30_RS20550	COG1716	ATPase activity
GPY30_RS20560	COG0484	heat shock protein binding
GPY30_RS20575	COG1324	tolerance protein
GPY30_RS20585	COG0366	Alpha amylase catalytic
GPY30_RS20590	COG4533	DNA binding
GPY30_RS20600	COG2050	protein possibly involved in aromatic compounds catabolism
GPY30_RS20610	COG0750	zinc metalloprotease
GPY30_RS20615	COG2067	long-chain fatty acid transport protein
GPY30_RS20620	COG2267	carboxylic ester hydrolase activity
GPY30_RS20650	COG0861	Integral membrane protein TerC family
GPY30_RS20655	COG0737	Belongs to the 5'-nucleotidase family
GPY30_RS20660	COG3593	DNA synthesis involved in DNA repair
GPY30_RS20670	COG0583	DNA-binding transcription factor activity
GPY30_RS20675	COG2116	formate transmembrane transporter activity
GPY30_RS20685	COG3038	cytochrome b561
GPY30_RS20700	COG0513	Belongs to the DEAD box helicase family
GPY30_RS20710	COG0840	transmembrane signaling receptor activity
GPY30_RS20715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY30_RS20740	COG2181	nitrate reductase activity
GPY30_RS20745	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GPY30_RS20760	COG2223	nitrite transmembrane transporter activity
GPY30_RS20765	COG3850	Histidine kinase
GPY30_RS20770	COG2197	response regulator
GPY30_RS20795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY30_RS20800	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GPY30_RS20815	COG2207	Transcriptional regulator
GPY30_RS20820	COG1979	alcohol dehydrogenase
GPY30_RS20840	COG1609	Transcriptional regulator
GPY30_RS20845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY30_RS20845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY30_RS20850	COG1105	Belongs to the carbohydrate kinase PfkB family
GPY30_RS20855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY30_RS20855	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GPY30_RS20855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY30_RS20870	COG2223	nitrite transmembrane transporter activity
GPY30_RS20880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY30_RS20920	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GPY30_RS20930	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPY30_RS20940	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPY30_RS20940	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPY30_RS20965	COG2017	converts alpha-aldose to the beta-anomer
GPY30_RS20975	COG1085	galactose-1-phosphate uridylyltransferase
GPY30_RS20980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPY30_RS20990	COG3250	beta-galactosidase activity
GPY30_RS21000	COG1129	ABC transporter
GPY30_RS21010	COG0419	ATPase involved in DNA repair
GPY30_RS21015	COG0420	3'-5' exonuclease activity
GPY30_RS21020	COG3706	GGDEF domain
GPY30_RS21055	COG0784	Response regulator, receiver
GPY30_RS21055	COG0835	chemotaxis
GPY30_RS21060	COG1609	Transcriptional regulator
GPY30_RS21070	COG1879	ABC-type sugar transport system periplasmic component
GPY30_RS21075	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPY30_RS21100	COG2315	Protein conserved in bacteria
GPY30_RS21120	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GPY30_RS21130	COG1126	abc transporter atp-binding protein
GPY30_RS21140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY30_RS21145	COG0765	amino acid transport
GPY30_RS21180	COG3209	COG3209 Rhs family protein
GPY30_RS21225	COG3209	COG3209 Rhs family protein
GPY30_RS21240	COG3501	Rhs element vgr protein
GPY30_RS21295	COG0631	protein serine/threonine phosphatase activity
GPY30_RS21330	COG0515	serine threonine protein kinase
GPY30_RS21330	COG2815	serine threonine protein kinase
GPY30_RS21335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPY30_RS21345	COG0456	acetyltransferase
GPY30_RS21350	COG0840	transmembrane signaling receptor activity
GPY30_RS21355	COG0840	transmembrane signaling receptor activity
GPY30_RS21370	COG2271	Major facilitator Superfamily
GPY30_RS21375	COG0584	glycerophosphoryl diester phosphodiesterase
GPY30_RS21390	COG0312	modulator of DNA gyrase
GPY30_RS21395	COG0312	modulator of DNA gyrase
GPY30_RS21400	COG5002	protein histidine kinase activity
GPY30_RS21400	COG5001	Diguanylate cyclase
GPY30_RS21405	COG0814	amino acid
GPY30_RS21425	COG3186	Phenylalanine-4-hydroxylase
GPY30_RS21430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY30_RS21435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY30_RS21455	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GPY30_RS21460	COG1454	alcohol dehydrogenase
GPY30_RS21485	COG0247	lactate metabolic process
GPY30_RS21490	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
GPY30_RS21495	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPY30_RS21515	COG5001	Diguanylate cyclase
GPY30_RS21515	COG1716	ATPase activity
GPY30_RS21530	COG4175	Glycine betaine
GPY30_RS21550	COG1012	belongs to the aldehyde dehydrogenase family
GPY30_RS21555	COG1309	transcriptional regulator
GPY30_RS21575	COG2113	Glycine betaine
GPY30_RS21585	COG3135	benzoate transporter
GPY30_RS21590	COG1396	sequence-specific DNA binding
GPY30_RS21605	COG0513	Belongs to the DEAD box helicase family
GPY30_RS21610	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GPY30_RS21625	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY30_RS21630	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY30_RS21640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY30_RS21650	COG1280	lysine exporter protein (LysE YggA)
GPY30_RS21675	COG1846	Transcriptional regulator
GPY30_RS21680	COG1764	response to oxidative stress
GPY30_RS21690	COG0697	spore germination
GPY30_RS21705	COG2814	Major facilitator Superfamily
GPY30_RS21710	COG0583	DNA-binding transcription factor activity
GPY30_RS21715	COG5001	Diguanylate cyclase
GPY30_RS21720	COG0739	heme binding
GPY30_RS21750	COG0366	Alpha amylase catalytic
GPY30_RS21765	COG0625	glutathione transferase activity
GPY30_RS21770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY30_RS21775	COG0784	Response regulator, receiver
GPY30_RS21775	COG0835	chemotaxis
GPY30_RS21785	COG0748	coenzyme F420 binding
GPY30_RS21790	COG3721	Heme iron utilization protein
GPY30_RS21800	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GPY30_RS21805	COG0811	peptide transport
GPY30_RS21810	COG0848	biopolymer transport protein
GPY30_RS21820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY30_RS21825	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GPY30_RS21870	COG0633	Ferredoxin
GPY30_RS21870	COG3217	Mosc domain protein beta barrel domain protein
GPY30_RS21870	COG0633	Ferredoxin
GPY30_RS21870	COG3217	Mosc domain protein beta barrel domain protein
GPY30_RS21875	COG0418	dihydroorotase activity
GPY30_RS21885	COG2354	Protein conserved in bacteria
GPY30_RS21945	COG0714	Associated with various cellular activities
GPY30_RS21965	COG2304	oxidoreductase activity
GPY30_RS21975	COG3706	GGDEF domain
GPY30_RS21985	COG0581	inorganic phosphate transmembrane transporter activity
GPY30_RS21990	COG0573	inorganic phosphate transmembrane transporter activity
GPY30_RS21995	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY30_RS22025	COG1770	oligopeptidase
GPY30_RS22030	COG0513	Belongs to the DEAD box helicase family
GPY30_RS22040	COG1388	LysM domain
GPY30_RS22040	COG1376	ErfK ybiS ycfS ynhG family protein
GPY30_RS22045	COG0415	Belongs to the DNA photolyase family
GPY30_RS22050	COG0789	Transcriptional regulator
GPY30_RS22075	COG3706	GGDEF domain
GPY30_RS22080	COG4720	Psort location CytoplasmicMembrane, score
GPY30_RS22085	COG1122	ATPase activity
GPY30_RS22100	COG0583	DNA-binding transcription factor activity
GPY30_RS22105	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPY30_RS22120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY30_RS22140	COG1067	ATP-dependent peptidase activity
GPY30_RS22150	COG4172	Belongs to the ABC transporter superfamily
GPY30_RS22155	COG1505	serine-type exopeptidase activity
GPY30_RS22160	COG0583	DNA-binding transcription factor activity
GPY30_RS22165	COG1620	l-lactate permease
GPY30_RS22170	COG1304	FMN binding
GPY30_RS22185	COG2814	Major facilitator Superfamily
GPY30_RS22215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY30_RS22225	COG3015	lipoprotein NlpE involved in copper resistance
GPY30_RS22230	COG1126	abc transporter atp-binding protein
GPY30_RS22235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY30_RS22240	COG4215	(ABC) transporter
GPY30_RS22245	COG4160	amino acid transport
GPY30_RS22260	COG0840	transmembrane signaling receptor activity
GPY30_RS22265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY30_RS22290	COG4067	protein conserved in archaea
GPY30_RS22290	COG0189	ligase activity
GPY30_RS22320	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY30_RS22330	COG5000	phosphorelay sensor kinase activity
GPY30_RS22330	COG5002	protein histidine kinase activity
GPY30_RS22335	COG0745	RESPONSE REGULATOR receiver
GPY30_RS22350	COG0840	transmembrane signaling receptor activity
GPY30_RS22355	COG0745	RESPONSE REGULATOR receiver
GPY30_RS22355	COG3706	GGDEF domain
GPY30_RS22360	COG0488	(ABC) transporter
GPY30_RS22380	COG0242	peptide deformylase activity
GPY30_RS22385	COG0589	response to stress
GPY30_RS22395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GPY30_RS22395	COG2111	Na H antiporter
GPY30_RS22415	COG2212	antiporter activity
GPY30_RS22420	COG1320	monovalent cation:proton antiporter activity
GPY30_RS22425	COG1253	flavin adenine dinucleotide binding
GPY30_RS22430	COG1686	Belongs to the peptidase S11 family
GPY30_RS22440	COG1629	transport
GPY30_RS22455	COG1760	l-serine dehydratase
GPY30_RS22460	COG3104	oligopeptide transport
GPY30_RS22475	COG2207	Transcriptional regulator
GPY30_RS22475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY30_RS22480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY30_RS22490	COG1011	Hydrolase
GPY30_RS22515	COG1765	OsmC-like protein
GPY30_RS22520	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY30_RS22520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY30_RS22525	COG3706	GGDEF domain
GPY30_RS22540	COG0840	transmembrane signaling receptor activity
GPY30_RS22565	COG2188	Transcriptional regulator
GPY30_RS22575	COG0745	RESPONSE REGULATOR receiver
GPY30_RS22585	COG3852	Histidine kinase
GPY30_RS22590	COG2200	EAL domain
GPY30_RS22590	COG2202	Pas domain
GPY30_RS22590	COG2199	diguanylate cyclase activity
GPY30_RS22600	COG4191	Histidine kinase
GPY30_RS22630	COG3842	ATPase activity
GPY30_RS22640	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GPY30_RS22645	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GPY30_RS22650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY30_RS22655	COG2375	cellular response to nickel ion
GPY30_RS22670	COG0668	transmembrane transport