locus-tag	class	description
A9237_RS00015	COG0840	transmembrane signaling receptor activity
A9237_RS00020	COG1254	Belongs to the acylphosphatase family
A9237_RS00025	COG2920	part of a sulfur-relay system
A9237_RS00035	COG0670	Belongs to the BI1 family
A9237_RS00040	COG1126	abc transporter atp-binding protein
A9237_RS00045	COG0765	amino acid transport
A9237_RS00050	COG4597	amino acid ABC transporter
A9237_RS00055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9237_RS00070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A9237_RS00095	COG3008	intermembrane lipid transfer
A9237_RS00100	COG2995	paraquat-inducible protein a
A9237_RS00105	COG1132	(ABC) transporter
A9237_RS00110	COG1956	GAF domain-containing protein
A9237_RS00115	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
A9237_RS00120	COG0793	Belongs to the peptidase S41A family
A9237_RS00130	COG0308	aminopeptidase N
A9237_RS00140	COG2902	Dehydrogenase
A9237_RS00165	COG0488	(ABC) transporter
A9237_RS00185	COG1067	ATP-dependent peptidase activity
A9237_RS00345	COG3278	Belongs to the heme-copper respiratory oxidase family
A9237_RS00360	COG2010	Cytochrome c
A9237_RS00370	COG2217	Heavy metal translocating P-type atpase
A9237_RS00385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A9237_RS00390	COG0589	response to stress
A9237_RS00415	COG3842	ATPase activity
A9237_RS00425	COG1177	transmembrane transport
A9237_RS00435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A9237_RS00440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A9237_RS00460	COG0437	4 iron, 4 sulfur cluster binding
A9237_RS00465	COG0243	molybdopterin cofactor binding
A9237_RS00465	COG3383	formate dehydrogenase (NAD+) activity
A9237_RS00475	COG3381	protein complex oligomerization
A9237_RS00495	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A9237_RS00500	COG0488	(ABC) transporter
A9237_RS00515	COG4191	Histidine kinase
A9237_RS00520	COG2204	response regulator
A9237_RS00530	COG4662	Binding-protein-dependent transport system inner membrane component
A9237_RS00535	COG3842	ATPase activity
A9237_RS00545	COG0303	'Molybdopterin
A9237_RS00560	COG1940	carbohydrate kinase activity
A9237_RS00565	COG3148	PFAM DTW domain containing protein
A9237_RS00610	COG0840	transmembrane signaling receptor activity
A9237_RS00615	COG0791	NLP P60 protein
A9237_RS00625	COG3706	GGDEF domain
A9237_RS00630	COG2201	protein-glutamate methylesterase activity
A9237_RS00635	COG3001	Fructosamine kinase
A9237_RS00645	COG0307	riboflavin synthase, alpha
A9237_RS00650	COG0534	Mate efflux family protein
A9237_RS00660	COG1793	dna ligase
A9237_RS00670	COG2885	chlorophyll binding
A9237_RS00690	COG2204	response regulator
A9237_RS00700	COG0438	transferase activity, transferring glycosyl groups
A9237_RS00740	COG0297	glycogen (starch) synthase activity
A9237_RS00745	COG1215	transferase activity, transferring glycosyl groups
A9237_RS00750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A9237_RS00760	COG3064	Membrane
A9237_RS00785	COG5001	Diguanylate cyclase
A9237_RS00785	COG3300	MHYT domain
A9237_RS00790	COG2205	protein histidine kinase activity
A9237_RS00790	COG3437	response regulator, receiver
A9237_RS00790	COG3850	Histidine kinase
A9237_RS00790	COG4999	Histidine kinase
A9237_RS00810	COG0110	maltose O-acetyltransferase activity
A9237_RS00815	COG0784	Response regulator, receiver
A9237_RS00815	COG2205	protein histidine kinase activity
A9237_RS00840	COG2315	Protein conserved in bacteria
A9237_RS00845	COG1846	Transcriptional regulator
A9237_RS00860	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A9237_RS00865	COG3247	response to pH
A9237_RS00870	COG0668	transmembrane transport
A9237_RS00885	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A9237_RS00890	COG0519	Catalyzes the synthesis of GMP from XMP
A9237_RS00895	COG0589	response to stress
A9237_RS00910	COG0583	DNA-binding transcription factor activity
A9237_RS00925	COG3083	sulfuric ester hydrolase activity
A9237_RS00940	COG0583	DNA-binding transcription factor activity
A9237_RS00945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9237_RS00955	COG0583	DNA-binding transcription factor activity
A9237_RS00960	COG0668	transmembrane transport
A9237_RS00980	COG0657	acetylesterase activity
A9237_RS00990	COG0625	glutathione transferase activity
A9237_RS01000	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
A9237_RS01015	COG2195	Cleaves the N-terminal amino acid of tripeptides
A9237_RS01025	COG0601	transmembrane transport
A9237_RS01030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9237_RS01035	COG0444	Belongs to the ABC transporter superfamily
A9237_RS01060	COG3291	Pkd domain containing protein
A9237_RS01085	COG0813	purine-nucleoside phosphorylase activity
A9237_RS01090	COG1177	transmembrane transport
A9237_RS01095	COG1176	ABC-type spermidine putrescine transport system, permease component I
A9237_RS01100	COG3842	ATPase activity
A9237_RS01105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A9237_RS01110	COG2423	ornithine cyclodeaminase activity
A9237_RS01120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9237_RS01125	COG3938	Belongs to the proline racemase family
A9237_RS01155	COG1451	nucleotide metabolic process
A9237_RS01165	COG5492	domain, Protein
A9237_RS01165	COG4932	domain protein
A9237_RS01180	COG2201	protein-glutamate methylesterase activity
A9237_RS01190	COG0784	Response regulator, receiver
A9237_RS01190	COG2205	protein histidine kinase activity
A9237_RS01270	COG0583	DNA-binding transcription factor activity
A9237_RS01300	COG4139	cobalamin transport
A9237_RS01325	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A9237_RS01335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A9237_RS01340	COG0702	epimerase
A9237_RS01345	COG1823	symporter activity
A9237_RS01355	COG2925	Exonuclease
A9237_RS01365	COG1346	cytolysis
A9237_RS01405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A9237_RS01410	COG1621	beta-fructofuranosidase activity
A9237_RS01420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9237_RS01420	COG0072	phenylalanine-tRNA ligase activity
A9237_RS01430	COG2199	diguanylate cyclase activity
A9237_RS01470	COG0251	oxidation-reduction process
A9237_RS01490	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A9237_RS01515	COG2188	Transcriptional regulator
A9237_RS01525	COG0010	Belongs to the arginase family
A9237_RS01535	COG2986	histidine ammonia-lyase
A9237_RS01555	COG0247	lactate metabolic process
A9237_RS01555	COG0277	FAD linked oxidase domain protein
A9237_RS01610	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
A9237_RS01615	COG1643	Atp-dependent helicase
A9237_RS01625	COG2949	membrane
A9237_RS01630	COG0471	metal ion transport
A9237_RS01635	COG3706	GGDEF domain
A9237_RS01655	COG0492	ferredoxin-NADP+ reductase activity
A9237_RS01660	COG4988	ABC transporter
A9237_RS01665	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A9237_RS01675	COG2610	gluconate transmembrane transporter activity
A9237_RS01680	COG0583	DNA-binding transcription factor activity
A9237_RS01685	COG2200	EAL domain
A9237_RS01725	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A9237_RS01735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9237_RS01735	COG4191	Histidine kinase
A9237_RS01750	COG3070	regulator of competence-specific genes
A9237_RS01760	COG2431	L-lysine efflux transmembrane transporter activity
A9237_RS01770	COG0076	glutamate decarboxylase activity
A9237_RS01775	COG1737	Transcriptional regulator
A9237_RS01785	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A9237_RS01795	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A9237_RS01825	COG4181	ATPase activity
A9237_RS01830	COG0534	Mate efflux family protein
A9237_RS01835	COG0702	epimerase
A9237_RS01840	COG4667	esterase of the alpha-beta hydrolase superfamily
A9237_RS01850	COG2814	Major facilitator Superfamily
A9237_RS01855	COG1187	pseudouridine synthase activity
A9237_RS01860	COG1061	Type III restriction enzyme res subunit
A9237_RS01865	COG2199	diguanylate cyclase activity
A9237_RS01920	COG3313	Fe-S protein
A9237_RS01930	COG0659	secondary active sulfate transmembrane transporter activity
A9237_RS01955	COG0493	'glutamate synthase
A9237_RS01965	COG0398	Pfam SNARE associated Golgi protein
A9237_RS01970	COG4134	Bacterial extracellular solute-binding protein
A9237_RS01975	COG4135	transport system, permease component
A9237_RS01980	COG4136	ATPase activity
A9237_RS01985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A9237_RS01990	COG3604	Transcriptional regulator
A9237_RS01995	COG1151	hydroxylamine reductase activity
A9237_RS02000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A9237_RS02010	COG0564	pseudouridine synthase activity
A9237_RS02020	COG0733	neurotransmitter:sodium symporter activity
A9237_RS02030	COG0626	cystathionine gamma-synthase activity
A9237_RS02035	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
A9237_RS02040	COG5380	lipid catabolic process
A9237_RS02045	COG2818	Glycosylase
A9237_RS02065	COG1983	PspC domain protein
A9237_RS02075	COG1842	Phage shock protein A
A9237_RS02080	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A9237_RS02090	COG4168	peptide transport system, permease
A9237_RS02105	COG4172	Belongs to the ABC transporter superfamily
A9237_RS02115	COG1227	inorganic diphosphatase activity
A9237_RS02130	COG0243	molybdopterin cofactor binding
A9237_RS02135	COG3005	denitrification pathway
A9237_RS02140	COG4459	periplasmic nitrate reductase
A9237_RS02145	COG0390	transport system, permease component
A9237_RS02150	COG2116	formate transmembrane transporter activity
A9237_RS02175	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A9237_RS02180	COG1435	thymidine kinase activity
A9237_RS02185	COG0215	cysteine-tRNA ligase activity
A9237_RS02190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A9237_RS02195	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A9237_RS02200	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
A9237_RS02205	COG3012	SEC-C Motif Domain Protein
A9237_RS02210	COG0140	phosphoribosyl-ATP diphosphatase activity
A9237_RS02210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A9237_RS02220	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A9237_RS02225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A9237_RS02230	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A9237_RS02230	COG0131	Imidazoleglycerol-phosphate dehydratase
A9237_RS02240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A9237_RS02250	COG1757	Na H antiporter
A9237_RS02260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A9237_RS02280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A9237_RS02290	COG2268	Band 7 protein
A9237_RS02300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A9237_RS02315	COG0300	oxidoreductase activity
A9237_RS02350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A9237_RS02355	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A9237_RS02375	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A9237_RS02385	COG1674	ftsk spoiiie
A9237_RS02395	COG0686	Belongs to the AlaDH PNT family
A9237_RS02405	COG0583	DNA-binding transcription factor activity
A9237_RS02425	COG0800	Aldolase
A9237_RS02430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A9237_RS02435	COG1917	Cupin 2, conserved barrel domain protein
A9237_RS02465	COG0402	S-adenosylhomocysteine deaminase activity
A9237_RS02475	COG3181	Tripartite tricarboxylate transporter family receptor
A9237_RS02490	COG4934	collagen metabolic process
A9237_RS02500	COG3568	Endonuclease Exonuclease Phosphatase
A9237_RS02535	COG2165	general secretion pathway protein
A9237_RS02545	COG1028	Short-chain dehydrogenase reductase Sdr
A9237_RS02550	COG1917	Cupin 2, conserved barrel domain protein
A9237_RS02565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A9237_RS02570	COG1904	glucuronate isomerase
A9237_RS02595	COG2186	Transcriptional regulator
A9237_RS02600	COG1028	Short-chain dehydrogenase reductase Sdr
A9237_RS02605	COG2186	Transcriptional regulator
A9237_RS02610	COG0517	IMP dehydrogenase activity
A9237_RS02615	COG2176	DNA-directed DNA polymerase activity
A9237_RS02625	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
A9237_RS02640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A9237_RS02665	COG1120	ATPase activity
A9237_RS02670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9237_RS02675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9237_RS02700	COG1288	antiporter activity
A9237_RS02710	COG2186	Transcriptional regulator
A9237_RS02720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A9237_RS02725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9237_RS02745	COG4771	TonB-dependent receptor
A9237_RS02750	COG0583	DNA-binding transcription factor activity
A9237_RS02775	COG2076	Multidrug Resistance protein
A9237_RS02790	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A9237_RS02805	COG0747	negative chemotaxis
A9237_RS02810	COG4608	Belongs to the ABC transporter superfamily
A9237_RS02815	COG0444	Belongs to the ABC transporter superfamily
A9237_RS02820	COG0534	Mate efflux family protein
A9237_RS02835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9237_RS02840	COG0601	transmembrane transport
A9237_RS02845	COG0747	negative chemotaxis
A9237_RS02865	COG2824	Alkylphosphonate utilization operon protein PhnA
A9237_RS02870	COG2723	6-phospho-beta-galactosidase activity
A9237_RS02875	COG1263	PTS System
A9237_RS02875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9237_RS02890	COG3119	arylsulfatase activity
A9237_RS02910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A9237_RS02935	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
A9237_RS02940	COG1715	Restriction endonuclease
A9237_RS02975	COG5002	protein histidine kinase activity
A9237_RS02975	COG0784	Response regulator, receiver
A9237_RS02985	COG0754	glutathionylspermidine amidase activity
A9237_RS02995	COG3766	membrane
A9237_RS03010	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
A9237_RS03015	COG2885	chlorophyll binding
A9237_RS03020	COG0823	Involved in the tonB-independent uptake of proteins
A9237_RS03035	COG0811	peptide transport
A9237_RS03040	COG0824	Thioesterase
A9237_RS03050	COG4890	Cyd operon protein YbgT
A9237_RS03055	COG1294	oxidase, subunit
A9237_RS03060	COG1271	oxidase subunit
A9237_RS03070	COG0632	four-way junction helicase activity
A9237_RS03075	COG0840	transmembrane signaling receptor activity
A9237_RS03090	COG1801	Protein of unknown function DUF72
A9237_RS03105	COG4067	protein conserved in archaea
A9237_RS03105	COG0189	ligase activity
A9237_RS03125	COG0318	PFAM AMP-dependent synthetase and ligase
A9237_RS03140	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
A9237_RS03145	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
A9237_RS03155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A9237_RS03160	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A9237_RS03165	COG0745	RESPONSE REGULATOR receiver
A9237_RS03180	COG3070	regulator of competence-specific genes
A9237_RS03200	COG0297	glycogen (starch) synthase activity
A9237_RS03205	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A9237_RS03210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A9237_RS03240	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A9237_RS03245	COG0542	response to heat
A9237_RS03255	COG1278	Cold shock
A9237_RS03265	COG1187	pseudouridine synthase activity
A9237_RS03270	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
A9237_RS03280	COG1199	ATP-dependent helicase activity
A9237_RS03285	COG0730	response to heat
A9237_RS03290	COG3923	Primosomal replication protein n
A9237_RS03300	COG0840	transmembrane signaling receptor activity
A9237_RS03305	COG0708	Exodeoxyribonuclease III
A9237_RS03315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9237_RS03355	COG1882	Formate acetyltransferase
A9237_RS03365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A9237_RS03380	COG2766	serine protein kinase
A9237_RS03385	COG2718	Belongs to the UPF0229 family
A9237_RS03390	COG2719	SpoVR family
A9237_RS03395	COG3385	transposase activity
A9237_RS03415	COG1132	(ABC) transporter
A9237_RS03430	COG4591	ABC-type transport system involved in lipoprotein release permease component
A9237_RS03435	COG1136	(ABC) transporter
A9237_RS03440	COG4591	ABC-type transport system involved in lipoprotein release permease component
A9237_RS03450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A9237_RS03465	COG1252	NADH dehydrogenase
A9237_RS03495	COG0537	adenosine 5'-monophosphoramidase activity
A9237_RS03500	COG0840	transmembrane signaling receptor activity
A9237_RS03530	COG0516	GMP reductase activity
A9237_RS03530	COG0517	IMP dehydrogenase activity
A9237_RS03535	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
A9237_RS03540	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A9237_RS03545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A9237_RS03550	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A9237_RS03560	COG2199	diguanylate cyclase activity
A9237_RS03575	COG3126	Type III secretion system lipoprotein chaperone (YscW)
A9237_RS03580	COG1946	Acyl-CoA thioesterase
A9237_RS03590	COG1522	sequence-specific DNA binding
A9237_RS03610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A9237_RS03665	COG2855	membrane
A9237_RS03675	COG0583	DNA-binding transcription factor activity
A9237_RS03680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9237_RS03680	COG2190	(PTS) system
A9237_RS03680	COG1263	PTS System
A9237_RS03695	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A9237_RS03700	COG0596	Alpha beta hydrolase
A9237_RS03710	COG1169	isochorismate synthase
A9237_RS03715	COG0436	Aminotransferase
A9237_RS03720	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
A9237_RS03740	COG1555	photosystem II stabilization
A9237_RS03745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A9237_RS03750	COG0776	regulation of translation
A9237_RS03755	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A9237_RS03795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A9237_RS03800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A9237_RS03805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A9237_RS03825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A9237_RS03830	COG0569	domain protein
A9237_RS03835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A9237_RS03840	COG0513	Belongs to the DEAD box helicase family
A9237_RS03845	COG1253	flavin adenine dinucleotide binding
A9237_RS03850	COG4771	TonB-dependent receptor
A9237_RS03865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A9237_RS03865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A9237_RS03870	COG3433	isochorismatase activity
A9237_RS03870	COG1535	isochorismatase
A9237_RS03875	COG1021	2,3-dihydroxybenzoate-AMP ligase
A9237_RS03880	COG1169	isochorismate synthase
A9237_RS03890	COG1028	Short-chain dehydrogenase reductase Sdr
A9237_RS03900	COG2226	methyltransferase
A9237_RS03915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A9237_RS03925	COG2951	lytic endotransglycosylase activity
A9237_RS03940	COG2894	cell division
A9237_RS03945	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
A9237_RS03950	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A9237_RS03955	COG0318	PFAM AMP-dependent synthetase and ligase
A9237_RS03960	COG2267	carboxylic ester hydrolase activity
A9237_RS03965	COG3065	identical protein binding
A9237_RS03975	COG1214	PFAM Peptidase M22, glycoprotease
A9237_RS03980	COG1199	ATP-dependent helicase activity
A9237_RS03985	COG0788	formyltetrahydrofolate deformylase activity
A9237_RS03990	COG3102	Protein conserved in bacteria
A9237_RS04015	COG1918	ferrous iron import across plasma membrane
A9237_RS04020	COG4977	sequence-specific DNA binding
A9237_RS04025	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
A9237_RS04030	COG1121	(ABC) transporter
A9237_RS04035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A9237_RS04050	COG0508	dehydrogenase complex catalyzes the overall conversion of
A9237_RS04055	COG0567	Dehydrogenase, E1 component
A9237_RS04065	COG1053	succinate dehydrogenase
A9237_RS04070	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A9237_RS04085	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A9237_RS04100	COG0033	Phosphoglucomutase
A9237_RS04105	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
A9237_RS04110	COG0596	Alpha beta hydrolase
A9237_RS04130	COG0735	belongs to the Fur family
A9237_RS04135	COG2165	general secretion pathway protein
A9237_RS04145	COG2190	(PTS) system
A9237_RS04145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9237_RS04145	COG1263	PTS System
A9237_RS04150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A9237_RS04155	COG1846	Transcriptional regulator
A9237_RS04155	COG1940	carbohydrate kinase activity
A9237_RS04160	COG4651	solute:proton antiporter activity
A9237_RS04160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A9237_RS04165	COG0367	asparagine synthase
A9237_RS04170	COG0250	Participates in transcription elongation, termination and antitermination
A9237_RS04175	COG3104	oligopeptide transport
A9237_RS04180	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
A9237_RS04195	COG3710	Transcriptional regulator
A9237_RS04215	COG0622	Phosphoesterase
A9237_RS04245	COG1090	epimerase
A9237_RS04250	COG0300	oxidoreductase activity
A9237_RS04260	COG3118	belongs to the thioredoxin family
A9237_RS04265	COG0457	Tetratricopeptide repeat
A9237_RS04265	COG3118	belongs to the thioredoxin family
A9237_RS04270	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
A9237_RS04275	COG1215	transferase activity, transferring glycosyl groups
A9237_RS04280	COG1215	transferase activity, transferring glycosyl groups
A9237_RS04300	COG2194	sulfuric ester hydrolase activity
A9237_RS04305	COG0330	HflC and HflK could
A9237_RS04345	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
A9237_RS04350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A9237_RS04360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9237_RS04365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A9237_RS04370	COG2190	(PTS) system
A9237_RS04375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A9237_RS04380	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A9237_RS04390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A9237_RS04405	COG1705	Flagellar rod assembly protein muramidase FlgJ
A9237_RS04405	COG3951	Flagellar rod assembly protein muramidase FlgJ
A9237_RS04410	COG1706	bacterial-type flagellum-dependent cell motility
A9237_RS04415	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
A9237_RS04425	COG4787	bacterial-type flagellum-dependent cell motility
A9237_RS04430	COG1749	Flagellar hook protein flgE
A9237_RS04440	COG1558	bacterial-type flagellum-dependent cell motility
A9237_RS04445	COG1815	bacterial-type flagellum-dependent cell motility
A9237_RS04450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A9237_RS04455	COG0835	chemotaxis
A9237_RS04455	COG0784	Response regulator, receiver
A9237_RS04510	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
A9237_RS04520	COG2217	Heavy metal translocating P-type atpase
A9237_RS04520	COG2608	mercury ion transmembrane transporter activity
A9237_RS04555	COG2840	Smr protein MutS2
A9237_RS04560	COG1187	pseudouridine synthase activity
A9237_RS04565	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A9237_RS04570	COG0737	Belongs to the 5'-nucleotidase family
A9237_RS04580	COG2912	Transglutaminase-like superfamily
A9237_RS04585	COG3094	Invasion gene expression up-regulator, SirB
A9237_RS04590	COG2890	protein-(glutamine-N5) methyltransferase activity
A9237_RS04615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A9237_RS04735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A9237_RS04745	COG1702	phosphate starvation-inducible protein PhoH
A9237_RS04755	COG4535	Mg2 and Co2 transporter CorC
A9237_RS04760	COG0815	Transfers the fatty acyl group on membrane lipoproteins
A9237_RS04765	COG2888	peptidyl-tyrosine sulfation
A9237_RS04770	COG0495	leucyl-tRNA aminoacylation
A9237_RS04775	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
A9237_RS04780	COG1466	dna polymerase III delta subunit
A9237_RS04785	COG0799	negative regulation of ribosome biogenesis
A9237_RS04795	COG0768	penicillin binding
A9237_RS04800	COG0772	Belongs to the SEDS family
A9237_RS04805	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A9237_RS04810	COG1686	Belongs to the peptidase S11 family
A9237_RS04830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A9237_RS04835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9237_RS04850	COG0366	Alpha amylase catalytic
A9237_RS04855	COG1263	PTS System
A9237_RS04855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9237_RS04865	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A9237_RS04870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A9237_RS04875	COG2011	ABC-type metal ion transport system permease component
A9237_RS04880	COG1464	Belongs to the NlpA lipoprotein family
A9237_RS04890	COG0737	Belongs to the 5'-nucleotidase family
A9237_RS04895	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
A9237_RS04920	COG1611	Belongs to the LOG family
A9237_RS04935	COG2363	Small membrane protein
A9237_RS04945	COG0583	DNA-binding transcription factor activity
A9237_RS04960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A9237_RS04970	COG0142	geranyltranstransferase activity
A9237_RS04980	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A9237_RS04985	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A9237_RS05010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A9237_RS05010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A9237_RS05015	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A9237_RS05020	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A9237_RS05035	COG1073	alpha beta
A9237_RS05045	COG2252	PERMEase
A9237_RS05050	COG2195	Cleaves the N-terminal amino acid of tripeptides
A9237_RS05085	COG0047	phosphoribosylformylglycinamidine synthase activity
A9237_RS05085	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A9237_RS05095	COG0590	tRNA wobble adenosine to inosine editing
A9237_RS05105	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A9237_RS05125	COG4969	Belongs to the N-Me-Phe pilin family
A9237_RS05145	COG1301	dicarboxylic acid transport
A9237_RS05165	COG0497	DNA recombination
A9237_RS05170	COG0456	acetyltransferase
A9237_RS05175	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A9237_RS05185	COG2914	Belongs to the UPF0125 (RnfH) family
A9237_RS05190	COG2867	negative regulation of translational initiation
A9237_RS05205	COG0583	DNA-binding transcription factor activity
A9237_RS05210	COG1289	transmembrane transporter activity
A9237_RS05230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A9237_RS05235	COG2873	o-acetylhomoserine
A9237_RS05250	COG0583	DNA-binding transcription factor activity
A9237_RS05260	COG1115	amino acid carrier protein
A9237_RS05265	COG1584	GPR1 FUN34 yaaH family protein
A9237_RS05275	COG1757	Na H antiporter
A9237_RS05285	COG0516	GMP reductase activity
A9237_RS05285	COG0517	IMP dehydrogenase activity
A9237_RS05300	COG2199	diguanylate cyclase activity
A9237_RS05300	COG2203	Gaf domain
A9237_RS05315	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A9237_RS05320	COG2976	Protein conserved in bacteria
A9237_RS05355	COG2975	iron-sulfur cluster assembly
A9237_RS05360	COG0633	Ferredoxin
A9237_RS05375	COG0316	Belongs to the HesB IscA family
A9237_RS05380	COG0822	iron-sulfur transferase activity
A9237_RS05395	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A9237_RS05400	COG0483	inositol monophosphate 1-phosphatase activity
A9237_RS05405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A9237_RS05410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A9237_RS05415	COG1862	Preprotein translocase
A9237_RS05440	COG0517	IMP dehydrogenase activity
A9237_RS05450	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A9237_RS05455	COG0583	DNA-binding transcription factor activity
A9237_RS05460	COG0450	alkyl hydroperoxide reductase
A9237_RS05495	COG0704	Plays a role in the regulation of phosphate uptake
A9237_RS05500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A9237_RS05505	COG0581	inorganic phosphate transmembrane transporter activity
A9237_RS05510	COG0573	inorganic phosphate transmembrane transporter activity
A9237_RS05515	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A9237_RS05520	COG0248	Ppx GppA phosphatase
A9237_RS05530	COG5002	protein histidine kinase activity
A9237_RS05535	COG0745	RESPONSE REGULATOR receiver
A9237_RS05545	COG0826	peptidase U32
A9237_RS05550	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A9237_RS05605	COG0542	response to heat
A9237_RS05610	COG1496	oxidoreductase activity
A9237_RS05615	COG0564	pseudouridine synthase activity
A9237_RS05620	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A9237_RS05625	COG0741	lytic transglycosylase activity
A9237_RS05630	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A9237_RS05635	COG0077	Prephenate dehydratase
A9237_RS05635	COG1605	Chorismate mutase
A9237_RS05640	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
A9237_RS05655	COG0488	(ABC) transporter
A9237_RS05665	COG0739	heme binding
A9237_RS05670	COG0287	Prephenate dehydrogenase
A9237_RS05670	COG1605	Chorismate mutase
A9237_RS05675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A9237_RS05685	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
A9237_RS05705	COG1966	Carbon starvation protein
A9237_RS05710	COG3275	phosphorelay sensor kinase activity
A9237_RS05715	COG3279	Response regulator of the LytR AlgR family
A9237_RS05720	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A9237_RS05725	COG1047	Peptidyl-prolyl cis-trans
A9237_RS05740	COG0196	riboflavin kinase activity
A9237_RS05745	COG0728	peptidoglycan biosynthetic process
A9237_RS05750	COG0268	Binds directly to 16S ribosomal RNA
A9237_RS05755	COG0640	Transcriptional regulator
A9237_RS05760	COG0583	DNA-binding transcription factor activity
A9237_RS05765	COG1283	sodium-dependent phosphate transmembrane transporter activity
A9237_RS05780	COG0730	response to heat
A9237_RS05805	COG0667	Aldo Keto reductase
A9237_RS05830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A9237_RS05835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A9237_RS05840	COG4974	Belongs to the 'phage' integrase family
A9237_RS05845	COG0716	FMN binding
A9237_RS05860	COG0513	Belongs to the DEAD box helicase family
A9237_RS05870	COG3022	response to hydroperoxide
A9237_RS05875	COG1115	amino acid carrier protein
A9237_RS05910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A9237_RS05915	COG0083	homoserine kinase activity
A9237_RS05930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A9237_RS05940	COG0745	RESPONSE REGULATOR receiver
A9237_RS05950	COG2198	Histidine kinase
A9237_RS05950	COG0784	Response regulator, receiver
A9237_RS05950	COG5002	protein histidine kinase activity
A9237_RS05955	COG2203	Gaf domain
A9237_RS05955	COG3706	GGDEF domain
A9237_RS05955	COG4251	negative regulation of phosphorylation
A9237_RS05955	COG5001	Diguanylate cyclase
A9237_RS05960	COG1242	4 iron, 4 sulfur cluster binding
A9237_RS05965	COG0070	glutamate synthase
A9237_RS05965	COG0067	glutamate synthase
A9237_RS05965	COG0069	glutamate synthase activity
A9237_RS05975	COG0069	glutamate synthase activity
A9237_RS05975	COG0070	glutamate synthase
A9237_RS05975	COG0067	glutamate synthase
A9237_RS05980	COG0493	'glutamate synthase
A9237_RS06005	COG2860	membrane
A9237_RS06010	COG0583	DNA-binding transcription factor activity
A9237_RS06015	COG0730	response to heat
A9237_RS06035	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A9237_RS06040	COG0505	Belongs to the CarA family
A9237_RS06050	COG0494	nUDIX hydrolase
A9237_RS06070	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A9237_RS06075	COG0849	cell division
A9237_RS06080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A9237_RS06095	COG0772	Belongs to the SEDS family
A9237_RS06110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A9237_RS06115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A9237_RS06120	COG0768	penicillin binding
A9237_RS06125	COG3116	cell division
A9237_RS06140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A9237_RS06155	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
A9237_RS06160	COG2823	Periplasmic or secreted lipoprotein
A9237_RS06165	COG2969	positive regulation of protein catabolic process
A9237_RS06170	COG0625	glutathione transferase activity
A9237_RS06175	COG2857	Cytochrome c1
A9237_RS06180	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A9237_RS06185	COG0723	plastoquinol--plastocyanin reductase activity
A9237_RS06205	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A9237_RS06210	COG3105	Protein conserved in bacteria
A9237_RS06215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A9237_RS06220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A9237_RS06225	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A9237_RS06235	COG3150	esterase
A9237_RS06245	COG3151	Protein conserved in bacteria
A9237_RS06250	COG0494	nUDIX hydrolase
A9237_RS06255	COG1538	Outer membrane efflux protein
A9237_RS06265	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
A9237_RS06275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A9237_RS06280	COG3025	triphosphatase activity
A9237_RS06285	COG1392	Phosphate transport regulator
A9237_RS06290	COG0306	phosphate transporter
A9237_RS06295	COG4991	sh3 domain protein
A9237_RS06305	COG0405	Gamma-glutamyltransferase
A9237_RS06320	COG3409	Peptidoglycan-binding domain 1 protein
A9237_RS06320	COG3267	Type II secretory pathway component ExeA
A9237_RS06335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A9237_RS06340	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A9237_RS06350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A9237_RS06355	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A9237_RS06360	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A9237_RS06365	COG1610	YqeY-like protein
A9237_RS06370	COG0358	DNA primase activity
A9237_RS06405	COG2213	PTS system mannitol-specific
A9237_RS06405	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9237_RS06415	COG3722	fumarate hydratase activity
A9237_RS06420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A9237_RS06425	COG5002	protein histidine kinase activity
A9237_RS06445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A9237_RS06450	COG1349	DNA-binding transcription factor activity
A9237_RS06455	COG0469	pyruvate kinase activity
A9237_RS06475	COG0028	Belongs to the TPP enzyme family
A9237_RS06480	COG1022	Amp-dependent synthetase and ligase
A9237_RS06485	COG0583	DNA-binding transcription factor activity
A9237_RS06505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A9237_RS06510	COG0473	3-isopropylmalate dehydrogenase activity
A9237_RS06530	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
A9237_RS06535	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A9237_RS06540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A9237_RS06545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A9237_RS06570	COG3610	response to peptide
A9237_RS06575	COG2966	Psort location CytoplasmicMembrane, score
A9237_RS06590	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A9237_RS06595	COG0142	geranyltranstransferase activity
A9237_RS06615	COG2358	TRAP transporter, solute receptor (TAXI family
A9237_RS06630	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
A9237_RS06635	COG1178	ABC-type Fe3 transport system permease component
A9237_RS06645	COG0163	prenyltransferase activity
A9237_RS06650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A9237_RS06660	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A9237_RS06675	COG2105	PFAM AIG2 family protein
A9237_RS06680	COG2911	Protein conserved in bacteria
A9237_RS06685	COG0729	surface antigen
A9237_RS06690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9237_RS06700	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
A9237_RS06715	COG1136	(ABC) transporter
A9237_RS06735	COG0529	Catalyzes the synthesis of activated sulfate
A9237_RS06740	COG0471	metal ion transport
A9237_RS06740	COG3273	potassium ion transport
A9237_RS06755	COG1648	precorrin-2 dehydrogenase activity
A9237_RS06755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A9237_RS06760	COG0737	Belongs to the 5'-nucleotidase family
A9237_RS06775	COG0513	Belongs to the DEAD box helicase family
A9237_RS06780	COG2153	protein acetylation
A9237_RS06795	COG0545	Peptidyl-prolyl cis-trans isomerase
A9237_RS06805	COG0203	ribosomal protein L17
A9237_RS06810	COG0202	RNA polymerase activity
A9237_RS06820	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A9237_RS06825	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A9237_RS06830	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A9237_RS06835	COG0201	protein transport
A9237_RS06845	COG1841	ribosomal large subunit assembly
A9237_RS06865	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A9237_RS06875	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A9237_RS06910	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A9237_RS06915	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A9237_RS06930	COG0088	Forms part of the polypeptide exit tunnel
A9237_RS06945	COG0254	rRNA binding
A9237_RS06950	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A9237_RS06955	COG1609	Transcriptional regulator
A9237_RS06975	COG1575	Belongs to the MenA family. Type 1 subfamily
A9237_RS06980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A9237_RS06985	COG3074	FtsZ-dependent cytokinesis
A9237_RS06990	COG1494	fructose-1,6-bisphosphatase
A9237_RS07025	COG0149	triose-phosphate isomerase activity
A9237_RS07050	COG1063	alcohol dehydrogenase
A9237_RS07075	COG0438	transferase activity, transferring glycosyl groups
A9237_RS07090	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A9237_RS07095	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A9237_RS07100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A9237_RS07105	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A9237_RS07110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A9237_RS07155	COG2089	acid synthase
A9237_RS07200	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A9237_RS07210	COG1560	Kdo2-lipid A biosynthetic process
A9237_RS07215	COG0859	PFAM glycosyl transferase family 9
A9237_RS07220	COG1519	Transferase
A9237_RS07230	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A9237_RS07240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A9237_RS07245	COG0438	transferase activity, transferring glycosyl groups
A9237_RS07250	COG0859	PFAM glycosyl transferase family 9
A9237_RS07305	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A9237_RS07315	COG1560	Kdo2-lipid A biosynthetic process
A9237_RS07320	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A9237_RS07325	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A9237_RS07330	COG1561	YicC-like family, N-terminal region
A9237_RS07335	COG0745	RESPONSE REGULATOR receiver
A9237_RS07360	COG4608	Belongs to the ABC transporter superfamily
A9237_RS07365	COG0444	Belongs to the ABC transporter superfamily
A9237_RS07370	COG0747	negative chemotaxis
A9237_RS07375	COG4239	(ABC) transporter, permease
A9237_RS07380	COG4174	ABC transporter (Permease)
A9237_RS07400	COG0811	peptide transport
A9237_RS07405	COG0848	biopolymer transport protein
A9237_RS07420	COG0194	GDP metabolic process
A9237_RS07425	COG1758	RNA polymerase activity
A9237_RS07430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A9237_RS07435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A9237_RS07440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A9237_RS07450	COG2233	PERMEase
A9237_RS07465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A9237_RS07475	COG2183	response to ionizing radiation
A9237_RS07490	COG1040	competence protein
A9237_RS07500	COG0494	nUDIX hydrolase
A9237_RS07505	COG1218	3'(2'),5'-bisphosphate nucleotidase
A9237_RS07515	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
A9237_RS07520	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
A9237_RS07525	COG3156	type II secretion system protein K
A9237_RS07530	COG4795	General secretion pathway protein
A9237_RS07535	COG2165	general secretion pathway protein
A9237_RS07540	COG2165	general secretion pathway protein
A9237_RS07545	COG2165	general secretion pathway protein
A9237_RS07550	COG1459	type II secretion system
A9237_RS07555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A9237_RS07565	COG3031	protein transport across the cell outer membrane
A9237_RS07570	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A9237_RS07590	COG0456	acetyltransferase
A9237_RS07595	COG1490	D-aminoacyl-tRNA deacylase activity
A9237_RS07615	COG1217	gtp-binding protein TYPA
A9237_RS07625	COG0174	glutamine synthetase
A9237_RS07635	COG3852	Histidine kinase
A9237_RS07640	COG2204	response regulator
A9237_RS07650	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A9237_RS07685	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A9237_RS07690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A9237_RS07690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A9237_RS07710	COG0084	hydrolase, TatD family'
A9237_RS07715	COG0805	protein transport
A9237_RS07720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A9237_RS07735	COG3165	ubiquinone biosynthetic process from chorismate
A9237_RS07745	COG1322	Protein conserved in bacteria
A9237_RS07780	COG2081	HI0933 family
A9237_RS07790	COG1528	Iron-storage protein
A9237_RS07795	COG0589	response to stress
A9237_RS07815	COG5001	Diguanylate cyclase
A9237_RS07815	COG5002	protein histidine kinase activity
A9237_RS07820	COG1522	sequence-specific DNA binding
A9237_RS07835	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A9237_RS07845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A9237_RS07850	COG0800	Aldolase
A9237_RS07855	COG2610	gluconate transmembrane transporter activity
A9237_RS07860	COG3265	gluconokinase activity
A9237_RS07865	COG0129	dihydroxy-acid dehydratase activity
A9237_RS07875	COG2076	Multidrug Resistance protein
A9237_RS07880	COG0583	DNA-binding transcription factor activity
A9237_RS07885	COG1609	Transcriptional regulator
A9237_RS07920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9237_RS07925	COG0601	transmembrane transport
A9237_RS07935	COG4172	Belongs to the ABC transporter superfamily
A9237_RS07945	COG0546	phosphoglycolate phosphatase activity
A9237_RS07985	COG1309	transcriptional regulator
A9237_RS07990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9237_RS07995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A9237_RS08000	COG2960	long-chain fatty acid transporting porin activity
A9237_RS08015	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A9237_RS08020	COG0583	DNA-binding transcription factor activity
A9237_RS08065	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A9237_RS08090	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A9237_RS08095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A9237_RS08100	COG0551	DNA topoisomerase type I activity
A9237_RS08110	COG0758	DNA mediated transformation
A9237_RS08120	COG0242	peptide deformylase activity
A9237_RS08130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A9237_RS08130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A9237_RS08135	COG0569	domain protein
A9237_RS08140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A9237_RS08150	COG1272	protein, Hemolysin III
A9237_RS08155	COG4326	sporulation control protein
A9237_RS08160	COG3084	Protein conserved in bacteria
A9237_RS08170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A9237_RS08175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A9237_RS08180	COG0204	Acyl-transferase
A9237_RS08190	COG0606	chelatase, subunit chli
A9237_RS08200	COG3978	acetolactate synthase activity
A9237_RS08205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A9237_RS08210	COG0129	dihydroxy-acid dehydratase activity
A9237_RS08220	COG3706	GGDEF domain
A9237_RS08225	COG0583	DNA-binding transcription factor activity
A9237_RS08230	COG2814	Major facilitator Superfamily
A9237_RS08240	COG0765	amino acid transport
A9237_RS08250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A9237_RS08260	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A9237_RS08290	COG3312	ion transport
A9237_RS08295	COG1475	DNA binding
A9237_RS08300	COG1192	Involved in chromosome partitioning
A9237_RS08315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A9237_RS08345	COG1126	abc transporter atp-binding protein
A9237_RS08365	COG0592	DNA-directed DNA polymerase activity
A9237_RS08375	COG0187	DNA topoisomerase II activity
A9237_RS08380	COG0071	Belongs to the small heat shock protein (HSP20) family
A9237_RS08385	COG3977	Valine--pyruvate aminotransferase
A9237_RS08390	COG0366	Alpha amylase catalytic
A9237_RS08405	COG2119	membrane
A9237_RS08415	COG0425	Belongs to the sulfur carrier protein TusA family
A9237_RS08430	COG0604	alcohol dehydrogenase
A9237_RS08435	COG0183	Belongs to the thiolase family
A9237_RS08445	COG1739	Uncharacterized protein family UPF0029
A9237_RS08450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A9237_RS08495	COG2132	Multicopper oxidase
A9237_RS08515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A9237_RS08520	COG2104	thiamine diphosphate biosynthetic process
A9237_RS08535	COG0006	proline dipeptidase activity
A9237_RS08535	COG0006	proline dipeptidase activity
A9237_RS08545	COG2814	Major facilitator Superfamily
A9237_RS08565	COG3220	belongs to the UPF0276 family
A9237_RS08575	COG0210	DNA helicase
A9237_RS08585	COG0405	Gamma-glutamyltransferase
A9237_RS08590	COG1280	lysine exporter protein (LysE YggA)
A9237_RS08600	COG2962	Rard protein
A9237_RS08605	COG0514	ATP-dependent DNA helicase (RecQ)
A9237_RS08615	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A9237_RS08635	COG3118	belongs to the thioredoxin family
A9237_RS08650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A9237_RS08655	COG0633	Ferredoxin
A9237_RS08705	COG2959	enzyme of heme biosynthesis
A9237_RS08710	COG1587	Uroporphyrinogen-III synthase
A9237_RS08720	COG3072	Adenylate cyclase
A9237_RS08735	COG0019	diaminopimelate decarboxylase activity
A9237_RS08755	COG1011	Hydrolase
A9237_RS08760	COG2199	diguanylate cyclase activity
A9237_RS08760	COG3287	FIST C domain
A9237_RS08760	COG2200	EAL domain
A9237_RS08765	COG3148	PFAM DTW domain containing protein
A9237_RS08780	COG0561	phosphatase activity
A9237_RS08785	COG2267	carboxylic ester hydrolase activity
A9237_RS08790	COG1280	lysine exporter protein (LysE YggA)
A9237_RS08795	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
A9237_RS08800	COG0640	Transcriptional regulator
A9237_RS08805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A9237_RS08855	COG2095	MarC family integral membrane protein
A9237_RS08865	COG0742	ribosomal rna small subunit methyltransferase
A9237_RS08870	COG0552	protein localization to endoplasmic reticulum
A9237_RS08875	COG2884	Cell division ATP-binding protein ftsE
A9237_RS08880	COG2177	Part of the ABC transporter FtsEX involved in
A9237_RS08895	COG0705	Rhomboid family
A9237_RS08900	COG1580	Controls the rotational direction of flagella during chemotaxis
A9237_RS08905	COG3161	chorismate lyase activity
A9237_RS08915	COG2937	Belongs to the GPAT DAPAT family
A9237_RS08935	COG0534	Mate efflux family protein
A9237_RS08940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A9237_RS09040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A9237_RS09050	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A9237_RS09090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A9237_RS09095	COG0250	Participates in transcription elongation, termination and antitermination
A9237_RS09100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A9237_RS09110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A9237_RS09115	COG0222	ribosome binding
A9237_RS09130	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
A9237_RS09135	COG2816	NAD+ diphosphatase activity
A9237_RS09145	COG1573	uracil-dna glycosylase
A9237_RS09155	COG3068	Protein conserved in bacteria
A9237_RS09160	COG1253	flavin adenine dinucleotide binding
A9237_RS09175	COG0151	Belongs to the GarS family
A9237_RS09190	COG0789	Transcriptional regulator
A9237_RS09195	COG3710	Transcriptional regulator
A9237_RS09210	COG0531	amino acid
A9237_RS09215	COG1982	Orn Lys Arg decarboxylase major
A9237_RS09260	COG2199	diguanylate cyclase activity
A9237_RS09265	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
A9237_RS09270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A9237_RS09280	COG0439	Biotin carboxylase
A9237_RS09285	COG0511	ligase activity, forming carbon-carbon bonds
A9237_RS09290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A9237_RS09295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A9237_RS09310	COG2814	Major facilitator Superfamily
A9237_RS09315	COG0784	Response regulator, receiver
A9237_RS09315	COG2205	protein histidine kinase activity
A9237_RS09315	COG2198	Histidine kinase
A9237_RS09335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A9237_RS09345	COG2095	MarC family integral membrane protein
A9237_RS09355	COG4232	protein-disulfide reductase activity
A9237_RS09360	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A9237_RS09365	COG1027	Aspartate ammonia-lyase
A9237_RS09370	COG3030	protein affecting phage T7 exclusion by the F plasmid
A9237_RS09375	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A9237_RS09385	COG2205	protein histidine kinase activity
A9237_RS09390	COG0745	RESPONSE REGULATOR receiver
A9237_RS09395	COG3678	ATP-independent chaperone mediated protein folding
A9237_RS09400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A9237_RS09410	COG0534	Mate efflux family protein
A9237_RS09435	COG1509	lysine 2,3-aminomutase activity
A9237_RS09440	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A9237_RS09465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A9237_RS09470	COG1053	succinate dehydrogenase
A9237_RS09495	COG4942	peptidase
A9237_RS09500	COG1045	serine acetyltransferase
A9237_RS09510	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
A9237_RS09515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9237_RS09520	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A9237_RS09530	COG0840	transmembrane signaling receptor activity
A9237_RS09535	COG0471	metal ion transport
A9237_RS09550	COG1162	GTPase activity
A9237_RS09555	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A9237_RS09630	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A9237_RS09635	COG0802	atpase or kinase
A9237_RS09640	COG0860	N-Acetylmuramoyl-L-alanine amidase
A9237_RS09645	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A9237_RS09660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A9237_RS09665	COG0330	HflC and HflK could
A9237_RS09670	COG0330	HflC and HflK could
A9237_RS09675	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
A9237_RS09680	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A9237_RS09685	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
A9237_RS09690	COG1017	nitric oxide dioxygenase activity
A9237_RS09690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A9237_RS09700	COG0557	exoribonuclease II activity
A9237_RS09705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A9237_RS09710	COG0546	phosphoglycolate phosphatase activity
A9237_RS09730	COG0512	Glutamine amidotransferase of anthranilate synthase
A9237_RS09735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A9237_RS09755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A9237_RS09760	COG3954	Phosphoribulokinase
A9237_RS09770	COG0429	hydrolase of the alpha beta-hydrolase fold
A9237_RS09780	COG0488	(ABC) transporter
A9237_RS09785	COG2249	NAD(P)H dehydrogenase (quinone) activity
A9237_RS09800	COG1047	Peptidyl-prolyl cis-trans
A9237_RS09805	COG1446	asparaginase
A9237_RS09820	COG0545	Peptidyl-prolyl cis-trans isomerase
A9237_RS09825	COG2964	Protein conserved in bacteria
A9237_RS09830	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A9237_RS09835	COG2923	Belongs to the DsrF TusC family
A9237_RS09840	COG2168	tRNA wobble position uridine thiolation
A9237_RS09855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A9237_RS09865	COG2906	2 iron, 2 sulfur cluster binding
A9237_RS09875	COG0281	malic enzyme
A9237_RS09885	COG0626	cystathionine gamma-synthase activity
A9237_RS09890	COG0460	homoserine dehydrogenase
A9237_RS09890	COG0527	aspartate kinase activity
A9237_RS09895	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A9237_RS09905	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
A9237_RS09915	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A9237_RS09930	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A9237_RS09930	COG0165	Argininosuccinate lyase
A9237_RS09940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A9237_RS09945	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A9237_RS09945	COG0678	peroxiredoxin activity
A9237_RS09955	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A9237_RS10000	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A9237_RS10005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A9237_RS10015	COG2965	DNA replication, synthesis of RNA primer
A9237_RS10035	COG0305	Participates in initiation and elongation during chromosome replication
A9237_RS10040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A9237_RS10050	COG0432	Pfam Uncharacterised protein family UPF0047
A9237_RS10065	COG0735	belongs to the Fur family
A9237_RS10075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A9237_RS10095	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A9237_RS10165	COG1410	methionine synthase
A9237_RS10165	COG0646	methionine synthase
A9237_RS10170	COG0527	aspartate kinase activity
A9237_RS10185	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A9237_RS10195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A9237_RS10210	COG0629	single-stranded DNA binding
A9237_RS10215	COG2200	EAL domain
A9237_RS10215	COG2199	diguanylate cyclase activity
A9237_RS10240	COG3409	Peptidoglycan-binding domain 1 protein
A9237_RS10240	COG3267	Type II secretory pathway component ExeA
A9237_RS10250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A9237_RS10255	COG1459	type II secretion system
A9237_RS10265	COG2165	general secretion pathway protein
A9237_RS10300	COG1077	Cell shape determining protein MreB Mrl
A9237_RS10305	COG1792	Involved in formation and maintenance of cell shape
A9237_RS10310	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A9237_RS10315	COG0424	maF-like protein
A9237_RS10325	COG3164	Protein of unknown function
A9237_RS10330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A9237_RS10335	COG0312	modulator of DNA gyrase
A9237_RS10340	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A9237_RS10355	COG0564	pseudouridine synthase activity
A9237_RS10360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A9237_RS10370	COG0312	modulator of DNA gyrase
A9237_RS10375	COG2239	Acts as a magnesium transporter
A9237_RS10380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9237_RS10390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9237_RS10395	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A9237_RS10405	COG1137	ATPase activity
A9237_RS10410	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A9237_RS10420	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A9237_RS10420	COG0517	IMP dehydrogenase activity
A9237_RS10430	COG1127	ABC transporter
A9237_RS10435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A9237_RS10440	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A9237_RS10445	COG2854	intermembrane phospholipid transfer
A9237_RS10455	COG5007	Belongs to the BolA IbaG family
A9237_RS10465	COG0204	Acyl-transferase
A9237_RS10470	COG0251	oxidation-reduction process
A9237_RS10510	COG0456	acetyltransferase
A9237_RS10520	COG0525	valine-tRNA ligase activity
A9237_RS10525	COG2927	DNA polymerase III (CHI subunit)
A9237_RS10535	COG0795	lipopolysaccharide-transporting ATPase activity
A9237_RS10540	COG0795	lipopolysaccharide-transporting ATPase activity
A9237_RS10550	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
A9237_RS10560	COG0726	polysaccharide deacetylase
A9237_RS10565	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9237_RS10575	COG1447	Phosphotransferase system cellobiose-specific component IIA
A9237_RS10580	COG1486	melibiose metabolic process
A9237_RS10590	COG1609	Transcriptional regulator
A9237_RS10595	COG3437	response regulator, receiver
A9237_RS10645	COG1012	belongs to the aldehyde dehydrogenase family
A9237_RS10745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A9237_RS10750	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A9237_RS10765	COG0762	integral membrane protein
A9237_RS10770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A9237_RS10775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A9237_RS10790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A9237_RS10795	COG1678	Uncharacterized ACR, COG1678
A9237_RS10800	COG0189	ligase activity
A9237_RS10805	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A9237_RS10810	COG2356	endonuclease I
A9237_RS10830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A9237_RS10850	COG0191	fructose-bisphosphate aldolase activity
A9237_RS10855	COG0668	transmembrane transport
A9237_RS10870	COG0583	DNA-binding transcription factor activity
A9237_RS10880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A9237_RS10890	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A9237_RS10900	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
A9237_RS10910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A9237_RS10915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A9237_RS10935	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
A9237_RS10945	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A9237_RS10950	COG1595	DNA-templated transcription, initiation
A9237_RS10965	COG3086	response to oxidative stress
A9237_RS10985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A9237_RS10990	COG1381	Involved in DNA repair and RecF pathway recombination
A9237_RS10995	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A9237_RS11020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A9237_RS11025	COG3956	TIGRFAM MazG family protein
A9237_RS11035	COG0148	phosphopyruvate hydratase activity
A9237_RS11045	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A9237_RS11050	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A9237_RS11075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A9237_RS11085	COG1546	Belongs to the CinA family
A9237_RS11090	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A9237_RS11105	COG0527	aspartate kinase activity
A9237_RS11195	COG3630	sodium ion export across plasma membrane
A9237_RS11200	COG5016	pyruvate
A9237_RS11200	COG0511	ligase activity, forming carbon-carbon bonds
A9237_RS11205	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A9237_RS11215	COG1238	metal cluster binding
A9237_RS11220	COG0612	Peptidase, M16
A9237_RS11240	COG4536	flavin adenine dinucleotide binding
A9237_RS11245	COG4137	Cytochrome C assembly protein
A9237_RS11250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A9237_RS11255	COG0228	four-way junction DNA binding
A9237_RS11270	COG0335	large ribosomal subunit rRNA binding
A9237_RS11275	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
A9237_RS11280	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
A9237_RS11285	COG0237	dephospho-CoA kinase activity
A9237_RS11295	COG1459	type II secretion system
A9237_RS11300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A9237_RS11325	COG2186	Transcriptional regulator
A9237_RS11330	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A9237_RS11335	COG0508	dehydrogenase complex catalyzes the overall conversion of
A9237_RS11340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A9237_RS11360	COG0288	reversible hydration of carbon dioxide
A9237_RS11365	COG0659	secondary active sulfate transmembrane transporter activity
A9237_RS11370	COG1131	(ABC) transporter
A9237_RS11375	COG0842	Transport permease protein
A9237_RS11380	COG1560	Kdo2-lipid A biosynthetic process
A9237_RS11395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A9237_RS11405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A9237_RS11420	COG1643	Atp-dependent helicase
A9237_RS11425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9237_RS11430	COG1752	Esterase of the alpha-beta hydrolase superfamily
A9237_RS11435	COG1049	propionate catabolic process, 2-methylcitrate cycle
A9237_RS11450	COG0004	ammonium transporteR
A9237_RS11455	COG1840	ABC-type Fe3 transport system, periplasmic component
A9237_RS11465	COG3842	ATPase activity
A9237_RS11470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A9237_RS11485	COG2971	BadF BadG BcrA BcrD
A9237_RS11495	COG4608	Belongs to the ABC transporter superfamily
A9237_RS11500	COG0444	Belongs to the ABC transporter superfamily
A9237_RS11505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9237_RS11515	COG0747	negative chemotaxis
A9237_RS11520	COG0784	Response regulator, receiver
A9237_RS11520	COG2205	protein histidine kinase activity
A9237_RS11535	COG0628	permease
A9237_RS11560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A9237_RS11565	COG0739	heme binding
A9237_RS11570	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A9237_RS11580	COG2027	D-alanyl-D-alanine carboxypeptidase
A9237_RS11585	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A9237_RS11590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A9237_RS11595	COG1534	Rna-binding protein
A9237_RS11605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A9237_RS11610	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A9237_RS11620	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A9237_RS11640	COG0195	Participates in both transcription termination and antitermination
A9237_RS11660	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A9237_RS11680	COG0534	Mate efflux family protein
A9237_RS11685	COG0826	peptidase U32
A9237_RS11690	COG0826	peptidase U32
A9237_RS11700	COG3154	lipid carrier protein
A9237_RS11705	COG3153	acetyltransferase
A9237_RS11725	COG3706	GGDEF domain
A9237_RS11735	COG0084	hydrolase, TatD family'
A9237_RS11740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A9237_RS11750	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A9237_RS11760	COG0813	purine-nucleoside phosphorylase activity
A9237_RS11770	COG0560	Phosphoserine phosphatase
A9237_RS11780	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A9237_RS11785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A9237_RS11790	COG0583	DNA-binding transcription factor activity
A9237_RS11825	COG1022	Amp-dependent synthetase and ligase
A9237_RS11830	COG0741	lytic transglycosylase activity
A9237_RS11855	COG4964	Belongs to the GSP D family
A9237_RS11915	COG0583	DNA-binding transcription factor activity
A9237_RS11920	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
A9237_RS11920	COG3408	Glycogen debranching enzyme
A9237_RS11930	COG0531	amino acid
A9237_RS11935	COG2731	YhcH YjgK YiaL family protein
A9237_RS11940	COG3250	beta-galactosidase activity
A9237_RS11945	COG1609	Transcriptional regulator
A9237_RS11950	COG0768	penicillin binding
A9237_RS11955	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A9237_RS11960	COG1085	galactose-1-phosphate uridylyltransferase
A9237_RS11970	COG2017	converts alpha-aldose to the beta-anomer
A9237_RS11975	COG1609	Transcriptional regulator
A9237_RS11980	COG1263	PTS System
A9237_RS11980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9237_RS11990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A9237_RS12005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A9237_RS12020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A9237_RS12040	COG1757	Na H antiporter
A9237_RS12060	COG2376	Dihydroxyacetone kinase
A9237_RS12065	COG1461	Dihydroxyacetone kinase
A9237_RS12075	COG3284	Transcriptional regulator
A9237_RS12080	COG3960	tartronate-semialdehyde synthase activity
A9237_RS12085	COG3622	Belongs to the hyi family
A9237_RS12090	COG2084	Dehydrogenase
A9237_RS12095	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A9237_RS12100	COG1349	DNA-binding transcription factor activity
A9237_RS12110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A9237_RS12115	COG2271	Major facilitator Superfamily
A9237_RS12120	COG0584	glycerophosphoryl diester phosphodiesterase
A9237_RS12125	COG2171	N-acyltransferase activity
A9237_RS12140	COG3141	response to X-ray
A9237_RS12160	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A9237_RS12165	COG1074	ATP-dependent DNA helicase activity
A9237_RS12170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A9237_RS12180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A9237_RS12180	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A9237_RS12195	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
A9237_RS12200	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A9237_RS12205	COG2166	iron-sulfur cluster assembly
A9237_RS12210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A9237_RS12215	COG0693	protein deglycase activity
A9237_RS12220	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A9237_RS12225	COG3248	Nucleoside-binding outer membrane protein
A9237_RS12245	COG1595	DNA-templated transcription, initiation
A9237_RS12275	COG0271	Belongs to the BolA IbaG family
A9237_RS12300	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
A9237_RS12310	COG1477	protein flavinylation
A9237_RS12325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A9237_RS12330	COG0514	ATP-dependent DNA helicase (RecQ)
A9237_RS12335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A9237_RS12350	COG0733	neurotransmitter:sodium symporter activity
A9237_RS12375	COG1720	tRNA m6t6A37 methyltransferase activity
A9237_RS12390	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A9237_RS12430	COG3098	single-species biofilm formation
A9237_RS12435	COG0564	pseudouridine synthase activity
A9237_RS12450	COG0024	Methionine aminopeptidase
A9237_RS12475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A9237_RS12480	COG0575	Belongs to the CDS family
A9237_RS12490	COG0750	zinc metalloprotease
A9237_RS12500	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
A9237_RS12505	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A9237_RS12530	COG0587	DNA-directed DNA polymerase activity
A9237_RS12550	COG0347	Belongs to the P(II) protein family
A9237_RS12565	COG1388	LysM domain
A9237_RS12565	COG0741	lytic transglycosylase activity
A9237_RS12575	COG2226	methyltransferase
A9237_RS12585	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A9237_RS12610	COG1960	acyl-CoA dehydrogenase activity
A9237_RS12615	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
A9237_RS12620	COG0121	glutamine amidotransferase
A9237_RS12625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A9237_RS12630	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A9237_RS12635	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A9237_RS12640	COG2233	PERMEase
A9237_RS12660	COG1393	Belongs to the ArsC family
A9237_RS12665	COG4783	chaperone-mediated protein folding
A9237_RS12680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A9237_RS12685	COG2716	regulation of RNA biosynthetic process
A9237_RS12690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A9237_RS12695	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
A9237_RS12715	COG1393	Belongs to the ArsC family
A9237_RS12745	COG2837	iron assimilation
A9237_RS12750	COG2169	Transcriptional regulator
A9237_RS12755	COG1486	melibiose metabolic process
A9237_RS12760	COG2211	Major facilitator Superfamily
A9237_RS12770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A9237_RS12780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A9237_RS12785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A9237_RS12790	COG1334	flagellar protein FlaG
A9237_RS12795	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A9237_RS12805	COG1516	flagellar protein fliS
A9237_RS12825	COG1677	Flagellar hook-basal body complex protein FliE
A9237_RS12835	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A9237_RS12890	COG1987	bacterial-type flagellum assembly
A9237_RS12895	COG1684	flagellar biosynthetic protein fliR
A9237_RS12930	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
A9237_RS12935	COG0643	Histidine kinase
A9237_RS12935	COG2198	Histidine kinase
A9237_RS12935	COG0784	Response regulator, receiver
A9237_RS12940	COG2201	protein-glutamate methylesterase activity
A9237_RS12945	COG1192	Involved in chromosome partitioning
A9237_RS12955	COG0835	chemotaxis
A9237_RS12965	COG4133	protoheme IX ABC transporter activity
A9237_RS12970	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A9237_RS12975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A9237_RS12990	COG1138	Cytochrome C-type biogenesis protein
A9237_RS12995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A9237_RS13005	COG3088	subunit of a heme lyase
A9237_RS13005	COG4235	cytochrome complex assembly
A9237_RS13010	COG2853	Lipoprotein
A9237_RS13015	COG2067	long-chain fatty acid transport protein
A9237_RS13040	COG0183	Belongs to the thiolase family
A9237_RS13060	COG2062	phosphohistidine phosphatase, SixA
A9237_RS13070	COG2890	protein-(glutamine-N5) methyltransferase activity
A9237_RS13080	COG2860	membrane
A9237_RS13085	COG3101	peptidyl-lysine hydroxylation
A9237_RS13105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A9237_RS13115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A9237_RS13120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A9237_RS13145	COG0285	dihydrofolate synthase activity
A9237_RS13150	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
A9237_RS13155	COG1286	toxin biosynthetic process
A9237_RS13160	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A9237_RS13165	COG0583	DNA-binding transcription factor activity
A9237_RS13170	COG0745	RESPONSE REGULATOR receiver
A9237_RS13175	COG2832	Protein of unknown function (DUF454)
A9237_RS13185	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A9237_RS13195	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A9237_RS13200	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A9237_RS13205	COG0814	amino acid
A9237_RS13210	COG0251	oxidation-reduction process
A9237_RS13220	COG2964	Protein conserved in bacteria
A9237_RS13235	COG2983	Belongs to the UPF0260 family
A9237_RS13240	COG2261	transglycosylase associated protein
A9237_RS13245	COG2985	domain, Protein
A9237_RS13250	COG0076	glutamate decarboxylase activity
A9237_RS13255	COG0668	transmembrane transport
A9237_RS13265	COG0346	lactoylglutathione lyase activity
A9237_RS13275	COG1785	Belongs to the alkaline phosphatase family
A9237_RS13295	COG2226	methyltransferase
A9237_RS13320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A9237_RS13325	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9237_RS13335	COG3139	Protein of unknown function (DUF1315)
A9237_RS13340	COG0252	asparaginase activity
A9237_RS13345	COG0616	signal peptide processing
A9237_RS13350	COG1902	pentaerythritol trinitrate reductase activity
A9237_RS13350	COG0446	pyridine nucleotide-disulphide oxidoreductase
A9237_RS13355	COG0778	Nitroreductase
A9237_RS13360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A9237_RS13375	COG0123	including yeast histone deacetylase and acetoin utilization protein
A9237_RS13380	COG4269	membrane
A9237_RS13395	COG3083	sulfuric ester hydrolase activity
A9237_RS13420	COG1757	Na H antiporter
A9237_RS13425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A9237_RS13430	COG2165	general secretion pathway protein
A9237_RS13435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A9237_RS13440	COG2095	MarC family integral membrane protein
A9237_RS13445	COG1012	belongs to the aldehyde dehydrogenase family
A9237_RS13445	COG1454	alcohol dehydrogenase
A9237_RS13465	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A9237_RS13500	COG2056	Na+-H+ antiporter family
A9237_RS13510	COG2885	chlorophyll binding
A9237_RS13520	COG0346	lactoylglutathione lyase activity
A9237_RS13525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A9237_RS13530	COG4660	Part of a membrane complex involved in electron transport
A9237_RS13535	COG4659	FMN binding
A9237_RS13540	COG4658	electron transport chain
A9237_RS13545	COG4656	Part of a membrane complex involved in electron transport
A9237_RS13555	COG4657	Part of a membrane complex involved in electron transport
A9237_RS13560	COG1882	Formate acetyltransferase
A9237_RS13570	COG0556	nucleotide-excision repair
A9237_RS13585	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A9237_RS13590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A9237_RS13595	COG0521	Mo-molybdopterin cofactor biosynthetic process
A9237_RS13605	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A9237_RS13610	COG0314	molybdopterin synthase activity
A9237_RS13620	COG0601	transmembrane transport
A9237_RS13625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A9237_RS13630	COG0444	Belongs to the ABC transporter superfamily
A9237_RS13640	COG0435	Glutathione S-transferase
A9237_RS13645	COG3174	membrane
A9237_RS13655	COG0280	phosphate acetyltransferase
A9237_RS13655	COG0857	belongs to the CobB CobQ family
A9237_RS13680	COG4120	Belongs to the binding-protein-dependent transport system permease family
A9237_RS13685	COG1122	ATPase activity
A9237_RS13690	COG0366	Alpha amylase catalytic
A9237_RS13695	COG3706	GGDEF domain
A9237_RS13700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A9237_RS13705	COG3318	Belongs to the UPF0149 family
A9237_RS13705	COG3012	SEC-C Motif Domain Protein
A9237_RS13710	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A9237_RS13720	COG2186	Transcriptional regulator
A9237_RS13750	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A9237_RS13755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A9237_RS13760	COG0659	secondary active sulfate transmembrane transporter activity
A9237_RS13770	COG1530	ribonuclease E activity
A9237_RS13780	COG0564	pseudouridine synthase activity
A9237_RS13785	COG0424	maF-like protein
A9237_RS13790	COG1399	metal-binding, possibly nucleic acid-binding protein
A9237_RS13805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A9237_RS13835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A9237_RS13850	COG0084	hydrolase, TatD family'
A9237_RS13855	COG1263	PTS System
A9237_RS13855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9237_RS13865	COG0733	neurotransmitter:sodium symporter activity
A9237_RS13875	COG4667	esterase of the alpha-beta hydrolase superfamily
A9237_RS13885	COG1940	carbohydrate kinase activity
A9237_RS13890	COG0835	chemotaxis
A9237_RS13890	COG0784	Response regulator, receiver
A9237_RS13910	COG1028	Short-chain dehydrogenase reductase Sdr
A9237_RS13915	COG0616	signal peptide processing
A9237_RS13925	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A9237_RS13930	COG0539	negative regulation of cytoplasmic translation
A9237_RS13940	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
A9237_RS13945	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
A9237_RS13955	COG4166	transmembrane transport
A9237_RS14015	COG3119	arylsulfatase activity
A9237_RS14020	COG1309	transcriptional regulator
A9237_RS14025	COG3009	Protein conserved in bacteria
A9237_RS14030	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A9237_RS14030	COG3008	intermembrane lipid transfer
A9237_RS14035	COG2995	paraquat-inducible protein a
A9237_RS14045	COG3258	Cytochrome c
A9237_RS14050	COG2863	cytochrome
A9237_RS14080	COG3250	beta-galactosidase activity
A9237_RS14090	COG4580	involved in the transport of maltose and maltodextrins
A9237_RS14105	COG2211	Major facilitator Superfamily
A9237_RS14110	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A9237_RS14125	COG4232	protein-disulfide reductase activity
A9237_RS14130	COG3118	belongs to the thioredoxin family
A9237_RS14160	COG3153	acetyltransferase
A9237_RS14200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9237_RS14210	COG1136	(ABC) transporter
A9237_RS14210	COG0577	efflux transmembrane transporter activity
A9237_RS14215	COG0577	efflux transmembrane transporter activity
A9237_RS14215	COG1136	(ABC) transporter
A9237_RS14220	COG0577	efflux transmembrane transporter activity
A9237_RS14220	COG1136	(ABC) transporter
A9237_RS14225	COG1609	Transcriptional regulator
A9237_RS14230	COG0366	Alpha amylase catalytic
A9237_RS14235	COG2182	Extracellular solute-binding protein
A9237_RS14240	COG2176	DNA-directed DNA polymerase activity
A9237_RS14255	COG0583	DNA-binding transcription factor activity
A9237_RS14325	COG5002	protein histidine kinase activity
A9237_RS14325	COG3850	Histidine kinase
A9237_RS14330	COG0745	RESPONSE REGULATOR receiver
A9237_RS14335	COG0463	Glycosyl transferase, family 2
A9237_RS14340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A9237_RS14350	COG0840	transmembrane signaling receptor activity
A9237_RS14355	COG2964	Protein conserved in bacteria
A9237_RS14370	COG0446	pyridine nucleotide-disulphide oxidoreductase
A9237_RS14395	COG1032	radical SAM domain protein
A9237_RS14400	COG4251	negative regulation of phosphorylation
A9237_RS14400	COG3706	GGDEF domain
A9237_RS14400	COG2203	Gaf domain
A9237_RS14400	COG5001	Diguanylate cyclase
A9237_RS14430	COG2350	Protein conserved in bacteria
A9237_RS14465	COG0159	tryptophan synthase activity
A9237_RS14475	COG0134	indole-3-glycerol-phosphate synthase activity
A9237_RS14475	COG0135	phosphoribosylanthranilate isomerase activity
A9237_RS14485	COG0512	Glutamine amidotransferase of anthranilate synthase
A9237_RS14490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A9237_RS14500	COG0613	PHP domain protein
A9237_RS14505	COG0009	L-threonylcarbamoyladenylate synthase
A9237_RS14515	COG1187	pseudouridine synthase activity
A9237_RS14535	COG0417	DNA replication proofreading
A9237_RS14540	COG2197	response regulator
A9237_RS14545	COG0322	excinuclease ABC activity
A9237_RS14590	COG0019	diaminopimelate decarboxylase activity
A9237_RS14605	COG1058	Belongs to the CinA family
A9237_RS14605	COG1546	Belongs to the CinA family
A9237_RS14615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A9237_RS14620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A9237_RS14630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A9237_RS14650	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
A9237_RS14660	COG0437	4 iron, 4 sulfur cluster binding
A9237_RS14665	COG3301	Polysulphide reductase, NrfD
A9237_RS14670	COG1138	Cytochrome C-type biogenesis protein
A9237_RS14680	COG3088	subunit of a heme lyase
A9237_RS14680	COG4235	cytochrome complex assembly
A9237_RS14690	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9237_RS14715	COG2989	Protein conserved in bacteria
A9237_RS14720	COG3108	Peptidase M15
A9237_RS14725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A9237_RS14740	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
A9237_RS14765	COG1846	Transcriptional regulator
A9237_RS14770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A9237_RS14775	COG0840	transmembrane signaling receptor activity
A9237_RS14795	COG1448	Aminotransferase
A9237_RS14800	COG3437	response regulator, receiver
A9237_RS14800	COG2770	Histidine kinase
A9237_RS14805	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A9237_RS14815	COG1609	Transcriptional regulator
A9237_RS14830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A9237_RS14845	COG0017	Asparaginyl-tRNA synthetase
A9237_RS14855	COG0720	synthase
A9237_RS14860	COG2197	response regulator
A9237_RS14870	COG3300	MHYT domain
A9237_RS14870	COG5001	Diguanylate cyclase
A9237_RS14875	COG1760	l-serine dehydratase
A9237_RS14880	COG0814	amino acid
A9237_RS14895	COG2205	protein histidine kinase activity
A9237_RS14895	COG0784	Response regulator, receiver
A9237_RS14900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A9237_RS14915	COG3106	COG3106 Predicted ATPase
A9237_RS14930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9237_RS15365	COG0791	NLP P60 protein
A9237_RS15505	COG1733	regulation of RNA biosynthetic process
A9237_RS15515	COG3340	Belongs to the peptidase S51 family
A9237_RS15535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A9237_RS15550	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A9237_RS15550	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A9237_RS15560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A9237_RS15565	COG1609	Transcriptional regulator
A9237_RS15575	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A9237_RS15590	COG0596	Alpha beta hydrolase
A9237_RS15605	COG0456	acetyltransferase
A9237_RS15610	COG0471	metal ion transport
A9237_RS15615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9237_RS15615	COG4191	Histidine kinase
A9237_RS15640	COG1328	CTP reductase activity
A9237_RS15645	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A9237_RS15655	COG0861	Integral membrane protein TerC family
A9237_RS15665	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A9237_RS15675	COG3706	GGDEF domain
A9237_RS15690	COG0814	amino acid
A9237_RS15710	COG1132	(ABC) transporter
A9237_RS15715	COG1132	(ABC) transporter
A9237_RS15730	COG0583	DNA-binding transcription factor activity
A9237_RS15755	COG0443	Heat shock 70 kDa protein
A9237_RS15760	COG0443	Heat shock 70 kDa protein
A9237_RS15770	COG3706	GGDEF domain
A9237_RS15795	COG3227	Zinc metalloprotease (Elastase)
A9237_RS15805	COG0243	molybdopterin cofactor binding
A9237_RS15810	COG0437	4 iron, 4 sulfur cluster binding
A9237_RS15815	COG3302	dmso reductase anchor subunit
A9237_RS15825	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A9237_RS15825	COG2221	Nitrite and sulphite reductase 4Fe-4S
A9237_RS15830	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A9237_RS15835	COG1643	Atp-dependent helicase
A9237_RS15860	COG3063	Type IV pilus biogenesis stability protein PilW
A9237_RS15895	COG0531	amino acid
A9237_RS15900	COG1280	lysine exporter protein (LysE YggA)
A9237_RS15905	COG0583	DNA-binding transcription factor activity
A9237_RS15910	COG0702	epimerase
A9237_RS15915	COG0583	DNA-binding transcription factor activity
A9237_RS15920	COG1560	Kdo2-lipid A biosynthetic process
A9237_RS15935	COG1846	Transcriptional regulator
A9237_RS15965	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A9237_RS15970	COG1280	lysine exporter protein (LysE YggA)
A9237_RS16000	COG1115	amino acid carrier protein
A9237_RS16050	COG0583	DNA-binding transcription factor activity
A9237_RS16055	COG1368	sulfuric ester hydrolase activity
A9237_RS16060	COG0215	cysteine-tRNA ligase activity
A9237_RS16065	COG0534	Mate efflux family protein
A9237_RS16070	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A9237_RS16080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A9237_RS16085	COG0456	acetyltransferase
A9237_RS16090	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A9237_RS16095	COG0662	Cupin 2, conserved barrel domain protein
A9237_RS16100	COG0527	aspartate kinase activity
A9237_RS16115	COG0583	DNA-binding transcription factor activity
A9237_RS16120	COG1858	cytochrome C peroxidase
A9237_RS16125	COG1404	Belongs to the peptidase S8 family
A9237_RS16130	COG0583	DNA-binding transcription factor activity
A9237_RS16135	COG0702	epimerase
A9237_RS16150	COG2169	Transcriptional regulator
A9237_RS16155	COG0697	spore germination
A9237_RS16160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A9237_RS16165	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
A9237_RS16180	COG4932	domain protein
A9237_RS16180	COG5492	domain, Protein
A9237_RS16200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9237_RS16215	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A9237_RS16220	COG3290	protein histidine kinase activity
A9237_RS16225	COG4565	transcriptional regulatory protein
A9237_RS16230	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A9237_RS16235	COG0363	glucosamine-6-phosphate deaminase activity
A9237_RS16240	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A9237_RS16275	COG1012	belongs to the aldehyde dehydrogenase family
A9237_RS16280	COG1902	pentaerythritol trinitrate reductase activity
A9237_RS16290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A9237_RS16295	COG2358	TRAP transporter, solute receptor (TAXI family
A9237_RS16300	COG0730	response to heat
A9237_RS16335	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A9237_RS16340	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A9237_RS16450	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A9237_RS16455	COG0372	Belongs to the citrate synthase family
A9237_RS16465	COG2828	Protein conserved in bacteria
A9237_RS16490	COG0561	phosphatase activity
A9237_RS16495	COG0602	queuosine metabolic process
A9237_RS16505	COG3706	GGDEF domain
A9237_RS16545	COG3835	regulator
A9237_RS16550	COG1929	Belongs to the glycerate kinase type-1 family
A9237_RS16555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A9237_RS16600	COG0456	acetyltransferase
A9237_RS16620	COG1028	Short-chain dehydrogenase reductase Sdr
A9237_RS16630	COG3005	denitrification pathway
A9237_RS16635	COG0243	molybdopterin cofactor binding
A9237_RS16640	COG5002	protein histidine kinase activity
A9237_RS16650	COG0671	phosphoesterase, PA-phosphatase related
A9237_RS16665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A9237_RS16670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A9237_RS16675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A9237_RS16680	COG1116	anion transmembrane transporter activity
A9237_RS16685	COG0351	phosphomethylpyrimidine kinase
A9237_RS16690	COG0312	modulator of DNA gyrase
A9237_RS16695	COG0312	modulator of DNA gyrase
A9237_RS16755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A9237_RS16765	COG0584	glycerophosphoryl diester phosphodiesterase
A9237_RS16770	COG0039	L-malate dehydrogenase activity
A9237_RS16775	COG0745	RESPONSE REGULATOR receiver
A9237_RS16795	COG0811	peptide transport
A9237_RS16800	COG0811	peptide transport
A9237_RS16805	COG0848	biopolymer transport protein
A9237_RS16850	COG0803	Belongs to the bacterial solute-binding protein 9 family
A9237_RS16855	COG1121	(ABC) transporter
A9237_RS16860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A9237_RS16875	COG1770	oligopeptidase
A9237_RS16880	COG2814	Major facilitator Superfamily
A9237_RS16885	COG0010	Belongs to the arginase family
A9237_RS16890	COG1166	arginine decarboxylase activity
A9237_RS16900	COG4067	protein conserved in archaea
A9237_RS16900	COG0189	ligase activity
A9237_RS16905	COG0189	ligase activity
A9237_RS16930	COG0583	DNA-binding transcription factor activity
A9237_RS16990	COG0579	oxidoreductase
A9237_RS17005	COG3033	Beta-eliminating lyase
A9237_RS17025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A9237_RS17030	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A9237_RS17050	COG3706	GGDEF domain
A9237_RS17065	COG3706	GGDEF domain
A9237_RS17070	COG0415	Belongs to the DNA photolyase family
A9237_RS17075	COG3046	protein related to deoxyribodipyrimidine photolyase
A9237_RS17090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9237_RS17090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9237_RS17095	COG1765	OsmC-like protein
A9237_RS17130	COG3842	ATPase activity
A9237_RS17145	COG0439	Biotin carboxylase
A9237_RS17160	COG1011	Hydrolase
A9237_RS17195	COG1511	domain protein
A9237_RS17195	COG3264	Mechanosensitive ion channel
A9237_RS17200	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A9237_RS17205	COG0698	ribose 5-phosphate isomerase
A9237_RS17220	COG1737	Transcriptional regulator
A9237_RS17225	COG3240	lipase activity
A9237_RS17255	COG1609	Transcriptional regulator
A9237_RS17265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A9237_RS17275	COG1840	ABC-type Fe3 transport system, periplasmic component
A9237_RS17285	COG3842	ATPase activity
A9237_RS17310	COG2990	Protein conserved in bacteria
A9237_RS17320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A9237_RS17325	COG2866	Carboxypeptidase
A9237_RS17335	COG0583	DNA-binding transcription factor activity
A9237_RS17360	COG3104	oligopeptide transport
A9237_RS17365	COG1760	l-serine dehydratase
A9237_RS17390	COG0741	lytic transglycosylase activity
A9237_RS17390	COG1388	LysM domain
A9237_RS17410	COG1815	bacterial-type flagellum-dependent cell motility
A9237_RS17415	COG1558	bacterial-type flagellum-dependent cell motility
A9237_RS17420	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A9237_RS17425	COG1749	Flagellar hook protein flgE
A9237_RS17430	COG4787	bacterial-type flagellum-dependent cell motility
A9237_RS17435	COG4786	Flagellar basal body rod
A9237_RS17440	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
A9237_RS17445	COG1706	bacterial-type flagellum-dependent cell motility
A9237_RS17455	COG4786	Flagellar basal body rod
A9237_RS17455	COG1256	bacterial-type flagellum assembly
A9237_RS17460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A9237_RS17485	COG0583	DNA-binding transcription factor activity
A9237_RS17505	COG1253	flavin adenine dinucleotide binding
A9237_RS17510	COG3710	Transcriptional regulator
A9237_RS17525	COG2226	methyltransferase
A9237_RS17575	COG1360	Flagellar Motor Protein
A9237_RS17580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A9237_RS17585	COG1191	sigma factor activity
A9237_RS17590	COG1580	Controls the rotational direction of flagella during chemotaxis
A9237_RS17605	COG1516	flagellar protein fliS
A9237_RS17610	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A9237_RS17620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A9237_RS17635	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A9237_RS17645	COG1987	bacterial-type flagellum assembly
A9237_RS17705	COG2200	EAL domain
A9237_RS17735	COG3188	usher protein
A9237_RS17790	COG0346	lactoylglutathione lyase activity
A9237_RS17815	COG0745	RESPONSE REGULATOR receiver
A9237_RS17840	COG0156	8-amino-7-oxononanoate synthase activity
A9237_RS17845	COG1063	alcohol dehydrogenase
A9237_RS17860	COG0668	transmembrane transport
A9237_RS17875	COG1304	FMN binding
A9237_RS17880	COG1620	l-lactate permease
A9237_RS17885	COG0583	DNA-binding transcription factor activity
A9237_RS17890	COG1505	serine-type exopeptidase activity
A9237_RS17895	COG4172	Belongs to the ABC transporter superfamily
A9237_RS17905	COG1067	ATP-dependent peptidase activity
A9237_RS17915	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A9237_RS17935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9237_RS17940	COG0437	4 iron, 4 sulfur cluster binding
A9237_RS17945	COG0348	domain, Protein
A9237_RS17960	COG0640	Transcriptional regulator
A9237_RS17970	COG2731	YhcH YjgK YiaL family protein
A9237_RS17985	COG1122	ATPase activity
A9237_RS17995	COG1566	PFAM secretion protein HlyD family protein
A9237_RS18025	COG0813	purine-nucleoside phosphorylase activity
A9237_RS18030	COG3272	Protein of unknown function (DUF1722)
A9237_RS18035	COG0789	Transcriptional regulator
A9237_RS18040	COG0415	Belongs to the DNA photolyase family
A9237_RS18045	COG1376	ErfK ybiS ycfS ynhG family protein
A9237_RS18045	COG1388	LysM domain
A9237_RS18090	COG0513	Belongs to the DEAD box helicase family
A9237_RS18095	COG1770	oligopeptidase
A9237_RS18100	COG4771	TonB-dependent receptor
A9237_RS18120	COG0840	transmembrane signaling receptor activity
A9237_RS18130	COG0573	inorganic phosphate transmembrane transporter activity
A9237_RS18135	COG0581	inorganic phosphate transmembrane transporter activity
A9237_RS18140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A9237_RS18155	COG2304	oxidoreductase activity
A9237_RS18175	COG0714	Associated with various cellular activities
A9237_RS18195	COG0840	transmembrane signaling receptor activity
A9237_RS18230	COG0110	maltose O-acetyltransferase activity
A9237_RS18235	COG2204	response regulator
A9237_RS18240	COG4191	Histidine kinase
A9237_RS18250	COG0573	inorganic phosphate transmembrane transporter activity
A9237_RS18260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A9237_RS18265	COG1028	Short-chain dehydrogenase reductase Sdr
A9237_RS18315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A9237_RS18320	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
A9237_RS18330	COG1252	NADH dehydrogenase
A9237_RS18335	COG1301	dicarboxylic acid transport
A9237_RS18345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A9237_RS18380	COG1566	PFAM secretion protein HlyD family protein
A9237_RS18385	COG0583	DNA-binding transcription factor activity
A9237_RS18400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9237_RS18400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9237_RS18400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9237_RS18405	COG2207	Transcriptional regulator
A9237_RS18415	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9237_RS18420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9237_RS18425	COG0583	DNA-binding transcription factor activity
A9237_RS18435	COG2084	Dehydrogenase
A9237_RS18440	COG0753	catalase activity
A9237_RS18450	COG2130	NADP-dependent
A9237_RS18455	COG1309	transcriptional regulator
A9237_RS18505	COG0489	protein tyrosine kinase activity
A9237_RS18505	COG3206	protein involved in exopolysaccharide biosynthesis
A9237_RS18520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A9237_RS18525	COG3842	ATPase activity
A9237_RS18540	COG1175	transmembrane transport
A9237_RS18545	COG3833	ABC-type maltose transport systems, permease component
A9237_RS18575	COG2354	Protein conserved in bacteria
A9237_RS18585	COG0401	homolog of Blt101
A9237_RS18590	COG3217	Mosc domain protein beta barrel domain protein
A9237_RS18590	COG0633	Ferredoxin
A9237_RS18590	COG3217	Mosc domain protein beta barrel domain protein
A9237_RS18590	COG0633	Ferredoxin
A9237_RS18600	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A9237_RS18640	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A9237_RS18645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9237_RS18655	COG0848	biopolymer transport protein
A9237_RS18660	COG0811	peptide transport
A9237_RS18665	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
A9237_RS18675	COG3721	Heme iron utilization protein
A9237_RS18680	COG0748	coenzyme F420 binding
A9237_RS18695	COG0835	chemotaxis
A9237_RS18695	COG0784	Response regulator, receiver
A9237_RS18700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A9237_RS18705	COG0366	Alpha amylase catalytic
A9237_RS18710	COG0604	alcohol dehydrogenase
A9237_RS18710	COG3321	synthase
A9237_RS18710	COG1028	Short-chain dehydrogenase reductase Sdr
A9237_RS18765	COG0583	DNA-binding transcription factor activity
A9237_RS18780	COG2249	NAD(P)H dehydrogenase (quinone) activity
A9237_RS18785	COG0583	DNA-binding transcription factor activity
A9237_RS18805	COG2814	Major facilitator Superfamily
A9237_RS18815	COG1335	isochorismatase
A9237_RS18825	COG0673	inositol 2-dehydrogenase activity
A9237_RS18835	COG2194	sulfuric ester hydrolase activity
A9237_RS18840	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A9237_RS18850	COG2205	protein histidine kinase activity
A9237_RS18855	COG0745	RESPONSE REGULATOR receiver
A9237_RS18865	COG4221	oxidoreductase activity
A9237_RS18880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A9237_RS18900	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9237_RS18910	COG2814	Major facilitator Superfamily
A9237_RS18925	COG1418	mRNA catabolic process
A9237_RS18940	COG0402	S-adenosylhomocysteine deaminase activity
A9237_RS18945	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A9237_RS18950	COG2239	Acts as a magnesium transporter
A9237_RS18955	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A9237_RS18960	COG1566	PFAM secretion protein HlyD family protein
A9237_RS18985	COG0745	RESPONSE REGULATOR receiver
A9237_RS18990	COG2205	protein histidine kinase activity
A9237_RS19010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9237_RS19020	COG0531	amino acid
A9237_RS19025	COG1522	sequence-specific DNA binding
A9237_RS19065	COG0673	inositol 2-dehydrogenase activity
A9237_RS19070	COG0534	Mate efflux family protein
A9237_RS19145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A9237_RS19150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A9237_RS19160	COG1280	lysine exporter protein (LysE YggA)
A9237_RS19170	COG0183	Belongs to the thiolase family
A9237_RS19190	COG3005	denitrification pathway
A9237_RS19210	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A9237_RS19215	COG3850	Histidine kinase
A9237_RS19220	COG2197	response regulator
A9237_RS19235	COG2195	Cleaves the N-terminal amino acid of tripeptides
A9237_RS19255	COG0840	transmembrane signaling receptor activity
A9237_RS19265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A9237_RS19270	COG0545	Peptidyl-prolyl cis-trans isomerase
A9237_RS19300	COG1278	Cold shock
A9237_RS19305	COG3036	rescue of stalled ribosome
A9237_RS19315	COG2199	diguanylate cyclase activity
A9237_RS19335	COG0577	efflux transmembrane transporter activity
A9237_RS19335	COG1136	(ABC) transporter
A9237_RS19365	COG1538	Outer membrane efflux protein
A9237_RS19370	COG0784	Response regulator, receiver
A9237_RS19370	COG2205	protein histidine kinase activity
A9237_RS19395	COG0840	transmembrane signaling receptor activity
A9237_RS19400	COG0783	Belongs to the Dps family
A9237_RS19410	COG1619	proteins homologs of microcin C7 resistance protein MccF
A9237_RS19415	COG2133	pyrroloquinoline quinone binding
A9237_RS19420	COG1454	alcohol dehydrogenase
A9237_RS19425	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
A9237_RS19445	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A9237_RS19450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A9237_RS19460	COG3186	Phenylalanine-4-hydroxylase
A9237_RS19490	COG3530	Putative quorum-sensing-regulated virulence factor
A9237_RS19520	COG0523	cobalamin synthesis protein
A9237_RS19530	COG0513	Belongs to the DEAD box helicase family
A9237_RS19550	COG2200	EAL domain
A9237_RS19555	COG1119	ATPase activity
A9237_RS19570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A9237_RS19585	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
A9237_RS19590	COG0513	Belongs to the DEAD box helicase family
A9237_RS19595	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A9237_RS19610	COG3278	Belongs to the heme-copper respiratory oxidase family
A9237_RS19635	COG1024	Enoyl-CoA hydratase
A9237_RS19640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A9237_RS19645	COG1960	acyl-CoA dehydrogenase activity
A9237_RS19655	COG0183	Belongs to the thiolase family
A9237_RS19670	COG1024	Enoyl-CoA hydratase
A9237_RS19675	COG1024	Enoyl-CoA hydratase
A9237_RS19685	COG1028	Short-chain dehydrogenase reductase Sdr
A9237_RS19695	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A9237_RS19700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A9237_RS19705	COG1845	cytochrome c oxidase, subunit III
A9237_RS19710	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A9237_RS19720	COG1902	pentaerythritol trinitrate reductase activity
A9237_RS19720	COG0446	pyridine nucleotide-disulphide oxidoreductase
A9237_RS19735	COG1012	belongs to the aldehyde dehydrogenase family
A9237_RS19745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A9237_RS19810	COG1126	abc transporter atp-binding protein
A9237_RS19815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9237_RS19820	COG4215	(ABC) transporter
A9237_RS19825	COG4160	amino acid transport
A9237_RS19830	COG0840	transmembrane signaling receptor activity
A9237_RS19850	COG3119	arylsulfatase activity
A9237_RS19855	COG0431	NADPH-dependent FMN reductase
A9237_RS19855	COG1053	succinate dehydrogenase
A9237_RS19855	COG3976	FMN-binding domain protein
A9237_RS19920	COG0443	Heat shock 70 kDa protein
A9237_RS19925	COG2847	Copper chaperone PCu(A)C
A9237_RS19955	COG0745	RESPONSE REGULATOR receiver
A9237_RS19975	COG1785	Belongs to the alkaline phosphatase family
A9237_RS20005	COG0814	amino acid
A9237_RS20010	COG5001	Diguanylate cyclase
A9237_RS20010	COG5002	protein histidine kinase activity
A9237_RS20020	COG0243	molybdopterin cofactor binding
A9237_RS20025	COG1648	precorrin-2 dehydrogenase activity
A9237_RS20025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A9237_RS20050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A9237_RS20050	COG1116	anion transmembrane transporter activity
A9237_RS20055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A9237_RS20060	COG1116	anion transmembrane transporter activity
A9237_RS20065	COG2146	nitrite reductase [NAD(P)H] activity
A9237_RS20065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A9237_RS20100	COG2165	general secretion pathway protein
A9237_RS20115	COG2165	general secretion pathway protein
A9237_RS20120	COG0745	RESPONSE REGULATOR receiver
A9237_RS20125	COG2205	protein histidine kinase activity
A9237_RS20125	COG2770	Histidine kinase
A9237_RS20130	COG2165	general secretion pathway protein
A9237_RS20150	COG1902	pentaerythritol trinitrate reductase activity
A9237_RS20160	COG1475	DNA binding
A9237_RS20180	COG0814	amino acid
A9237_RS20195	COG1414	Transcriptional regulator
A9237_RS20205	COG0589	response to stress
A9237_RS20215	COG2111	Na H antiporter
A9237_RS20215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A9237_RS20220	COG1006	Multisubunit Na H antiporter MnhC subunit
A9237_RS20225	COG0651	ATP synthesis coupled electron transport
A9237_RS20230	COG1863	multisubunit Na H antiporter MnhE subunit
A9237_RS20235	COG2212	antiporter activity
A9237_RS20240	COG1320	monovalent cation:proton antiporter activity
A9237_RS20245	COG1294	oxidase, subunit
A9237_RS20250	COG1271	oxidase subunit
A9237_RS20260	COG0583	DNA-binding transcription factor activity
A9237_RS20270	COG0739	heme binding
A9237_RS20305	COG0628	permease
A9237_RS20330	COG2249	NAD(P)H dehydrogenase (quinone) activity
A9237_RS20355	COG3321	synthase
A9237_RS20355	COG0604	alcohol dehydrogenase
A9237_RS20360	COG1024	Enoyl-CoA hydratase
A9237_RS20375	COG0523	cobalamin synthesis protein
A9237_RS20395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A9237_RS20410	COG2207	Transcriptional regulator
A9237_RS20410	COG0662	Cupin 2, conserved barrel domain protein
A9237_RS20500	COG1132	(ABC) transporter
A9237_RS20520	COG0583	DNA-binding transcription factor activity
A9237_RS20525	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A9237_RS20540	COG2814	Major facilitator Superfamily
A9237_RS20550	COG1028	Short-chain dehydrogenase reductase Sdr
A9237_RS20570	COG1204	response to ionizing radiation
A9237_RS20580	COG0509	glycine decarboxylation via glycine cleavage system
A9237_RS20585	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A9237_RS20595	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A9237_RS20605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9237_RS20610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9237_RS20640	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A9237_RS20640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9237_RS20640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9237_RS20645	COG1105	Belongs to the carbohydrate kinase PfkB family
A9237_RS20650	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9237_RS20650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9237_RS20655	COG1609	Transcriptional regulator
A9237_RS20670	COG2199	diguanylate cyclase activity
A9237_RS20670	COG2200	EAL domain
A9237_RS20670	COG2203	Gaf domain
A9237_RS20675	COG0765	amino acid transport
A9237_RS20680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A9237_RS20685	COG0765	amino acid transport
A9237_RS20690	COG1126	abc transporter atp-binding protein
A9237_RS20700	COG1979	alcohol dehydrogenase
A9237_RS20705	COG2207	Transcriptional regulator
A9237_RS20715	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A9237_RS20725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A9237_RS20740	COG0784	Response regulator, receiver
A9237_RS20740	COG3437	response regulator, receiver
A9237_RS20745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A9237_RS20755	COG0840	transmembrane signaling receptor activity
A9237_RS20760	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
A9237_RS20765	COG0513	Belongs to the DEAD box helicase family
A9237_RS20770	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A9237_RS20785	COG3038	cytochrome b561
A9237_RS20795	COG2116	formate transmembrane transporter activity
A9237_RS20805	COG0583	DNA-binding transcription factor activity
A9237_RS20815	COG3593	DNA synthesis involved in DNA repair
A9237_RS20820	COG0737	Belongs to the 5'-nucleotidase family
A9237_RS20840	COG1410	methionine synthase
A9237_RS20840	COG0646	methionine synthase
A9237_RS20855	COG2267	carboxylic ester hydrolase activity
A9237_RS20875	COG2050	protein possibly involved in aromatic compounds catabolism
A9237_RS20910	COG0484	heat shock protein binding
A9237_RS20920	COG3300	MHYT domain
A9237_RS20920	COG5001	Diguanylate cyclase
A9237_RS20925	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A9237_RS20935	COG4181	ATPase activity
A9237_RS20940	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
A9237_RS20950	COG1984	allophanate hydrolase subunit 2
A9237_RS20955	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A9237_RS20965	COG5002	protein histidine kinase activity
A9237_RS20965	COG5001	Diguanylate cyclase
A9237_RS20965	COG3447	MASE1 domain protein
A9237_RS20970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A9237_RS20980	COG0583	DNA-binding transcription factor activity
A9237_RS20985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9237_RS20985	COG0045	succinate-CoA ligase (ADP-forming) activity
A9237_RS20985	COG1042	CoA-binding domain protein
A9237_RS21005	COG0023	Translation Initiation Factor
A9237_RS21130	COG3140	Belongs to the UPF0181 family
A9237_RS21155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A9237_RS21160	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A9237_RS21185	COG5001	Diguanylate cyclase
A9237_RS21185	COG4251	negative regulation of phosphorylation
A9237_RS21185	COG3706	GGDEF domain
A9237_RS21185	COG2203	Gaf domain
A9237_RS21195	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
A9237_RS21200	COG4149	molybdate abc transporter
A9237_RS21205	COG0725	ABC transporter, periplasmic molybdate-binding protein
A9237_RS21215	COG3111	PFAM Bacterial OB fold (BOF) protein
A9237_RS21240	COG0534	Mate efflux family protein
A9237_RS21245	COG0602	queuosine metabolic process
A9237_RS21250	COG1328	CTP reductase activity
A9237_RS21330	COG2197	response regulator
A9237_RS21335	COG3851	Histidine kinase
A9237_RS21340	COG2271	Major facilitator Superfamily
A9237_RS21345	COG1482	cell wall glycoprotein biosynthetic process
A9237_RS21355	COG0628	permease
A9237_RS21365	COG1566	PFAM secretion protein HlyD family protein
A9237_RS21395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A9237_RS21400	COG3118	belongs to the thioredoxin family
A9237_RS21410	COG0745	RESPONSE REGULATOR receiver
A9237_RS21410	COG2205	protein histidine kinase activity
A9237_RS21410	COG3292	Two component regulator propeller
A9237_RS21415	COG0534	Mate efflux family protein
A9237_RS21435	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A9237_RS21455	COG2116	formate transmembrane transporter activity
A9237_RS21465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A9237_RS21475	COG2199	diguanylate cyclase activity
A9237_RS21555	COG0277	FAD linked oxidase domain protein
A9237_RS21560	COG0583	DNA-binding transcription factor activity
A9237_RS21565	COG1472	Belongs to the glycosyl hydrolase 3 family
A9237_RS21575	COG2425	protein containing a von Willebrand factor type A (vWA) domain
A9237_RS21590	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
A9237_RS21600	COG1288	antiporter activity
A9237_RS21610	COG2814	Major facilitator Superfamily
A9237_RS21620	COG3040	lipid binding
A9237_RS21650	COG3469	chitinase activity
A9237_RS21660	COG0419	ATPase involved in DNA repair
A9237_RS21665	COG0420	3'-5' exonuclease activity
A9237_RS21680	COG3209	COG3209 Rhs family protein
A9237_RS21750	COG0631	protein serine/threonine phosphatase activity
A9237_RS21785	COG2815	serine threonine protein kinase
A9237_RS21785	COG0515	serine threonine protein kinase
A9237_RS21815	COG0346	lactoylglutathione lyase activity
A9237_RS21820	COG1902	pentaerythritol trinitrate reductase activity
A9237_RS21830	COG2755	lipolytic protein G-D-S-L family
A9237_RS21830	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A9237_RS21840	COG5642	Protein of unknown function (DUF2384)
A9237_RS21855	COG1234	tRNA 3'-trailer cleavage
A9237_RS21860	COG2067	long-chain fatty acid transport protein
A9237_RS21910	COG0671	phosphoesterase, PA-phosphatase related
A9237_RS21925	COG2962	Rard protein
A9237_RS21935	COG2165	general secretion pathway protein
A9237_RS21940	COG0784	Response regulator, receiver
A9237_RS21940	COG0835	chemotaxis
A9237_RS21945	COG0778	Nitroreductase
A9237_RS21955	COG2197	response regulator
A9237_RS21965	COG3706	GGDEF domain
A9237_RS21970	COG2197	response regulator
A9237_RS21975	COG3300	MHYT domain
A9237_RS21975	COG5001	Diguanylate cyclase
A9237_RS21980	COG0784	Response regulator, receiver
A9237_RS21980	COG2205	protein histidine kinase activity
A9237_RS21995	COG4771	TonB-dependent receptor
A9237_RS22065	COG1522	sequence-specific DNA binding
A9237_RS22100	COG0515	serine threonine protein kinase
A9237_RS22125	COG3501	Rhs element vgr protein
A9237_RS22140	COG2204	response regulator
A9237_RS22165	COG0739	heme binding
A9237_RS22170	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A9237_RS22200	COG3069	C4-dicarboxylate transmembrane transporter activity
A9237_RS22205	COG1704	LemA family
A9237_RS22210	COG0501	Belongs to the peptidase M48B family
A9237_RS22235	COG0641	radical SAM
A9237_RS22255	COG3111	PFAM Bacterial OB fold (BOF) protein
A9237_RS22260	COG1597	lipid kinase activity
A9237_RS22265	COG0583	DNA-binding transcription factor activity
A9237_RS22275	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A9237_RS22285	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A9237_RS22345	COG0714	Associated with various cellular activities
A9237_RS22350	COG0641	radical SAM
A9237_RS22355	COG3119	arylsulfatase activity
A9237_RS22360	COG0583	DNA-binding transcription factor activity
A9237_RS22365	COG3063	Type IV pilus biogenesis stability protein PilW
A9237_RS22370	COG3119	arylsulfatase activity
A9237_RS22375	COG3119	arylsulfatase activity
A9237_RS22380	COG3119	arylsulfatase activity
A9237_RS22395	COG1629	transport
A9237_RS22395	COG4771	TonB-dependent receptor
A9237_RS22410	COG2205	protein histidine kinase activity
A9237_RS22410	COG0784	Response regulator, receiver
A9237_RS22410	COG2198	Histidine kinase
A9237_RS22415	COG1879	ABC-type sugar transport system periplasmic component
A9237_RS22425	COG0210	DNA helicase
A9237_RS22430	COG1289	transmembrane transporter activity
A9237_RS22465	COG4206	TonB-dependent receptor
A9237_RS22475	COG0789	Transcriptional regulator
A9237_RS22480	COG4604	ABC transporter, ATP-binding protein
A9237_RS22485	COG4605	iron ion homeostasis
A9237_RS22490	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9237_RS22495	COG4607	ABC-type enterochelin transport system periplasmic component
A9237_RS22510	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A9237_RS22525	COG1609	Transcriptional regulator
A9237_RS22530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A9237_RS22540	COG1172	Belongs to the binding-protein-dependent transport system permease family
A9237_RS22545	COG1129	ABC transporter
A9237_RS22555	COG5001	Diguanylate cyclase
A9237_RS22560	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A9237_RS22565	COG1794	racemase activity, acting on amino acids and derivatives
A9237_RS22570	COG1051	belongs to the nudix hydrolase family
A9237_RS22595	COG0586	Pfam SNARE associated Golgi protein
A9237_RS22615	COG0745	RESPONSE REGULATOR receiver
A9237_RS22660	COG0583	DNA-binding transcription factor activity
A9237_RS22670	COG2205	protein histidine kinase activity
A9237_RS22670	COG0784	Response regulator, receiver
A9237_RS22680	COG0784	Response regulator, receiver
A9237_RS22680	COG2205	protein histidine kinase activity
A9237_RS22715	COG0330	HflC and HflK could
A9237_RS22750	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
A9237_RS22760	COG2985	domain, Protein
A9237_RS22785	COG2272	Belongs to the type-B carboxylesterase lipase family
A9237_RS22790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A9237_RS22795	COG0729	surface antigen
A9237_RS22810	COG4175	Glycine betaine
A9237_RS22810	COG0517	IMP dehydrogenase activity
A9237_RS22815	COG4176	ABC-type proline glycine betaine transport system permease component
A9237_RS22855	COG3706	GGDEF domain
A9237_RS22865	COG0402	S-adenosylhomocysteine deaminase activity
A9237_RS22880	COG2860	membrane
A9237_RS22885	COG1473	amidohydrolase
A9237_RS22890	COG0583	DNA-binding transcription factor activity
A9237_RS22900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A9237_RS22900	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A9237_RS22915	COG4989	oxidoreductase activity
A9237_RS22940	COG1914	H( )-stimulated, divalent metal cation uptake system
A9237_RS22980	COG2897	thiosulfate sulfurtransferase activity
A9237_RS23010	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A9237_RS23015	COG0840	transmembrane signaling receptor activity
A9237_RS23020	COG2814	Major facilitator Superfamily
A9237_RS23025	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A9237_RS23040	COG1612	heme a metabolic process
A9237_RS23060	COG1845	cytochrome c oxidase, subunit III
A9237_RS23065	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
A9237_RS23080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A9237_RS23090	COG1280	lysine exporter protein (LysE YggA)
A9237_RS23110	COG0179	Fumarylacetoacetate (FAA) hydrolase
A9237_RS23130	COG0697	spore germination
A9237_RS23145	COG2814	Major facilitator Superfamily
A9237_RS23150	COG0583	DNA-binding transcription factor activity
A9237_RS23180	COG1120	ATPase activity
A9237_RS23185	COG5001	Diguanylate cyclase
A9237_RS23190	COG0739	heme binding
A9237_RS23210	COG3314	Sporulation integral membrane protein YlbJ
A9237_RS23225	COG0814	amino acid
A9237_RS23245	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A9237_RS23250	COG1072	(Pantothenic acid kinase))
A9237_RS23260	COG1063	alcohol dehydrogenase
A9237_RS23265	COG2213	PTS system mannitol-specific
A9237_RS23270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9237_RS23275	COG2188	Transcriptional regulator
A9237_RS23280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9237_RS23280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9237_RS23280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A9237_RS23285	COG0383	alpha-mannosidase activity
A9237_RS23290	COG1482	cell wall glycoprotein biosynthetic process
A9237_RS23300	COG4989	oxidoreductase activity
A9237_RS23320	COG1733	regulation of RNA biosynthetic process
A9237_RS23335	COG0798	PFAM Bile acid sodium symporter
A9237_RS23350	COG1881	PFAM PEBP family protein
A9237_RS23355	COG0251	oxidation-reduction process
A9237_RS23360	COG2706	6-phosphogluconolactonase activity
A9237_RS23370	COG0800	Aldolase
A9237_RS23375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A9237_RS23380	COG4145	pantothenate transmembrane transporter activity
A9237_RS23390	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
A9237_RS23415	COG1131	(ABC) transporter
A9237_RS23420	COG0842	Transport permease protein
A9237_RS23435	COG3383	formate dehydrogenase (NAD+) activity
A9237_RS23455	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A9237_RS23495	COG3321	synthase
A9237_RS23495	COG1028	Short-chain dehydrogenase reductase Sdr
A9237_RS23495	COG0604	alcohol dehydrogenase
A9237_RS23500	COG0456	acetyltransferase
A9237_RS23515	COG0494	nUDIX hydrolase
A9237_RS23530	COG1858	cytochrome C peroxidase
A9237_RS23535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A9237_RS23545	COG2067	long-chain fatty acid transport protein
A9237_RS23555	COG1505	serine-type exopeptidase activity
A9237_RS23560	COG0488	(ABC) transporter
A9237_RS23565	COG1720	tRNA m6t6A37 methyltransferase activity
A9237_RS23585	COG0589	response to stress
A9237_RS23610	COG1175	transmembrane transport
A9237_RS23615	COG0395	ABC-type sugar transport system, permease component
A9237_RS23620	COG3842	ATPase activity
A9237_RS23660	COG0523	cobalamin synthesis protein
A9237_RS23670	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A9237_RS23680	COG4667	esterase of the alpha-beta hydrolase superfamily
A9237_RS23690	COG1741	Belongs to the pirin family
A9237_RS23695	COG1278	Cold shock
A9237_RS23710	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A9237_RS23715	COG3706	GGDEF domain
A9237_RS23740	COG2226	methyltransferase
A9237_RS23750	COG3706	GGDEF domain
A9237_RS23755	COG1686	Belongs to the peptidase S11 family
A9237_RS23760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A9237_RS23765	COG2249	NAD(P)H dehydrogenase (quinone) activity
A9237_RS23775	COG0625	glutathione transferase activity
A9237_RS23785	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A9237_RS23795	COG1028	Short-chain dehydrogenase reductase Sdr
A9237_RS23820	COG3746	phosphate-selective porin O and P
A9237_RS23835	COG1028	Short-chain dehydrogenase reductase Sdr
A9237_RS23845	COG0583	DNA-binding transcription factor activity
A9237_RS23850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A9237_RS23850	COG2207	Transcriptional regulator
A9237_RS23855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A9237_RS23885	COG0513	Belongs to the DEAD box helicase family
A9237_RS23895	COG0583	DNA-binding transcription factor activity
A9237_RS23920	COG1028	Short-chain dehydrogenase reductase Sdr
A9237_RS23925	COG2814	Major facilitator Superfamily
A9237_RS23935	COG1902	pentaerythritol trinitrate reductase activity
A9237_RS23955	COG3122	Protein conserved in bacteria
A9237_RS23960	COG0583	DNA-binding transcription factor activity
A9237_RS23965	COG0604	alcohol dehydrogenase
A9237_RS23980	COG0583	DNA-binding transcription factor activity
A9237_RS23985	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A9237_RS24000	COG0252	asparaginase activity
A9237_RS24010	COG0574	Belongs to the PEP-utilizing enzyme family
A9237_RS24010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A9237_RS24020	COG2197	response regulator
A9237_RS24025	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A9237_RS24075	COG0583	DNA-binding transcription factor activity
A9237_RS24080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A9237_RS24095	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A9237_RS24100	COG0786	glutamate:sodium symporter activity
A9237_RS24135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A9237_RS24145	COG0318	PFAM AMP-dependent synthetase and ligase
A9237_RS24165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A9237_RS24180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A9237_RS24190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A9237_RS24235	COG1621	beta-fructofuranosidase activity
A9237_RS24240	COG1263	PTS System
A9237_RS24240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9237_RS24245	COG2188	Transcriptional regulator
A9237_RS24260	COG4948	Mandelate Racemase Muconate Lactonizing
A9237_RS24275	COG3385	transposase activity
A9237_RS24310	COG1342	Belongs to the UPF0251 family
A9237_RS24320	COG4176	ABC-type proline glycine betaine transport system permease component
A9237_RS24325	COG3448	diguanylate cyclase activity
A9237_RS24325	COG4175	Glycine betaine
A9237_RS24340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A9237_RS24345	COG0583	DNA-binding transcription factor activity
A9237_RS24395	COG1335	isochorismatase
A9237_RS24410	COG0753	catalase activity
A9237_RS24430	COG1482	cell wall glycoprotein biosynthetic process
A9237_RS24435	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A9237_RS24440	COG1263	PTS System
A9237_RS24440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9237_RS24445	COG1609	Transcriptional regulator
A9237_RS24450	COG1349	DNA-binding transcription factor activity
A9237_RS24455	COG0346	lactoylglutathione lyase activity
A9237_RS24460	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9237_RS24460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A9237_RS24470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A9237_RS24475	COG3537	Alpha-1,2-mannosidase
A9237_RS24480	COG3537	Alpha-1,2-mannosidase
A9237_RS24490	COG3537	Alpha-1,2-mannosidase
A9237_RS24495	COG3537	Alpha-1,2-mannosidase
A9237_RS24500	COG0737	Belongs to the 5'-nucleotidase family
A9237_RS24530	COG1280	lysine exporter protein (LysE YggA)
A9237_RS24535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A9237_RS24555	COG0583	DNA-binding transcription factor activity
A9237_RS24570	COG0488	(ABC) transporter
A9237_RS24575	COG0435	Glutathione S-transferase
A9237_RS24580	COG0431	NADPH-dependent FMN reductase
A9237_RS24585	COG0583	DNA-binding transcription factor activity
A9237_RS24590	COG4628	conserved protein (DUF2132)
A9237_RS24595	COG0488	(ABC) transporter
A9237_RS24610	COG0346	lactoylglutathione lyase activity
A9237_RS24615	COG0384	phenazine biosynthesis protein PhzF
A9237_RS24635	COG3220	belongs to the UPF0276 family
A9237_RS24650	COG1271	oxidase subunit
A9237_RS24655	COG1294	oxidase, subunit
A9237_RS24695	COG2207	Transcriptional regulator
A9237_RS24705	COG1882	Formate acetyltransferase
A9237_RS24710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A9237_RS24715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A9237_RS24730	COG2205	protein histidine kinase activity
A9237_RS24735	COG0745	RESPONSE REGULATOR receiver
A9237_RS24745	COG0454	-acetyltransferase
A9237_RS24750	COG0148	phosphopyruvate hydratase activity
A9237_RS24760	COG2814	Major facilitator Superfamily
A9237_RS24780	COG2988	succinylglutamate desuccinylase activity
A9237_RS24820	COG0628	permease
A9237_RS24825	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
A9237_RS24840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A9237_RS24850	COG4628	conserved protein (DUF2132)
A9237_RS24855	COG0583	DNA-binding transcription factor activity
A9237_RS24880	COG1686	Belongs to the peptidase S11 family
A9237_RS24900	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A9237_RS24905	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A9237_RS24930	COG0415	Belongs to the DNA photolyase family
A9237_RS24935	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
A9237_RS24945	COG4667	esterase of the alpha-beta hydrolase superfamily
A9237_RS24950	COG2095	MarC family integral membrane protein
A9237_RS24970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A9237_RS24990	COG0583	DNA-binding transcription factor activity
A9237_RS24995	COG2814	Major facilitator Superfamily
A9237_RS25025	COG1301	dicarboxylic acid transport
A9237_RS25030	COG3339	Conserved Protein
A9237_RS25035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A9237_RS25040	COG0700	Nucleoside recognition
A9237_RS25045	COG3366	ferrous iron transmembrane transporter activity
A9237_RS25060	COG0366	Alpha amylase catalytic
A9237_RS25065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A9237_RS25070	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A9237_RS25075	COG1640	4-alpha-glucanotransferase
A9237_RS25080	COG0058	SHG alpha-glucan phosphorylase activity
A9237_RS25105	COG1999	signal sequence binding
A9237_RS25120	COG1162	GTPase activity
A9237_RS25125	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
A9237_RS25130	COG0673	inositol 2-dehydrogenase activity
A9237_RS25155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A9237_RS25160	COG0673	inositol 2-dehydrogenase activity
A9237_RS25165	COG3962	Belongs to the TPP enzyme family
A9237_RS25175	COG0477	Major facilitator Superfamily
A9237_RS25175	COG2814	Major facilitator Superfamily
A9237_RS25195	COG0183	Belongs to the thiolase family
A9237_RS25200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A9237_RS25225	COG0531	amino acid
A9237_RS25230	COG1982	Orn Lys Arg decarboxylase major
A9237_RS25250	COG2356	endonuclease I
A9237_RS25260	COG0366	Alpha amylase catalytic
A9237_RS25285	COG2199	diguanylate cyclase activity
A9237_RS25285	COG2203	Gaf domain
A9237_RS25310	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A9237_RS25325	COG1263	PTS System
A9237_RS25325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9237_RS25330	COG1760	l-serine dehydratase
A9237_RS25355	COG1609	Transcriptional regulator
A9237_RS25365	COG2814	Major facilitator Superfamily
A9237_RS25370	COG3214	Protein conserved in bacteria
A9237_RS25380	COG4771	TonB-dependent receptor
A9237_RS25385	COG0583	DNA-binding transcription factor activity
A9237_RS25390	COG4607	ABC-type enterochelin transport system periplasmic component
A9237_RS25395	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A9237_RS25400	COG4605	iron ion homeostasis
A9237_RS25405	COG4604	ABC transporter, ATP-binding protein
A9237_RS25435	COG0739	heme binding
A9237_RS25450	COG0800	Aldolase
A9237_RS25455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A9237_RS25460	COG1263	PTS System
A9237_RS25460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9237_RS25460	COG2190	(PTS) system
A9237_RS25470	COG2188	Transcriptional regulator
A9237_RS25480	COG1621	beta-fructofuranosidase activity
A9237_RS25490	COG3842	ATPase activity
A9237_RS25495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A9237_RS25500	COG1554	hydrolase, family 65, central catalytic
A9237_RS25505	COG0395	ABC-type sugar transport system, permease component
A9237_RS25510	COG1175	transmembrane transport
A9237_RS25540	COG3121	Chaperone
A9237_RS25545	COG3188	usher protein
A9237_RS25575	COG0612	Peptidase, M16
A9237_RS25580	COG0840	transmembrane signaling receptor activity
A9237_RS25595	COG0826	peptidase U32
A9237_RS25610	COG0667	Aldo Keto reductase
A9237_RS25625	COG2249	NAD(P)H dehydrogenase (quinone) activity
A9237_RS25635	COG0583	DNA-binding transcription factor activity
A9237_RS25645	COG1136	(ABC) transporter
A9237_RS25650	COG0577	efflux transmembrane transporter activity
A9237_RS25695	COG1764	response to oxidative stress
A9237_RS25700	COG1846	Transcriptional regulator
A9237_RS25710	COG3634	alkyl hydroperoxide reductase activity
A9237_RS25760	COG0346	lactoylglutathione lyase activity
A9237_RS25765	COG0840	transmembrane signaling receptor activity
A9237_RS25770	COG0583	DNA-binding transcription factor activity
A9237_RS25775	COG1486	melibiose metabolic process
A9237_RS25790	COG1522	sequence-specific DNA binding
A9237_RS25805	COG2258	MOSC domain
A9237_RS25810	COG2153	protein acetylation
A9237_RS25820	COG3713	MltA-interacting MipA family protein
A9237_RS25825	COG0513	Belongs to the DEAD box helicase family
A9237_RS25845	COG1595	DNA-templated transcription, initiation
A9237_RS25855	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A9237_RS25860	COG1312	Catalyzes the dehydration of D-mannonate
A9237_RS25865	COG2186	Transcriptional regulator
A9237_RS25875	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A9237_RS25885	COG0246	Mannitol dehydrogenase
A9237_RS25890	COG1904	glucuronate isomerase
A9237_RS25895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A9237_RS25900	COG0800	Aldolase
A9237_RS25930	COG1132	(ABC) transporter
A9237_RS25950	COG0406	alpha-ribazole phosphatase activity
A9237_RS26005	COG2197	response regulator
A9237_RS26010	COG2409	Drug exporters of the RND superfamily
A9237_RS26150	COG4166	transmembrane transport
A9237_RS26165	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A9237_RS26170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A9237_RS26170	COG1263	PTS System
A9237_RS26175	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A9237_RS26200	COG1444	tRNA N-acetyltransferase activity
A9237_RS26230	COG4608	Belongs to the ABC transporter superfamily
A9237_RS26235	COG0444	Belongs to the ABC transporter superfamily
A9237_RS26245	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
A9237_RS26245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A9237_RS26270	COG0772	Belongs to the SEDS family
A9237_RS26285	COG1566	PFAM secretion protein HlyD family protein
A9237_RS26290	COG0583	DNA-binding transcription factor activity
A9237_RS26300	COG1136	(ABC) transporter
A9237_RS26320	COG3275	phosphorelay sensor kinase activity
A9237_RS26325	COG3279	Response regulator of the LytR AlgR family
A9237_RS26335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A9237_RS26360	COG0786	glutamate:sodium symporter activity
A9237_RS26375	COG1131	(ABC) transporter
A9237_RS26380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A9237_RS26385	COG0786	glutamate:sodium symporter activity
A9237_RS26390	COG3539	Fimbrial protein
A9237_RS26395	COG3121	Chaperone
A9237_RS26400	COG3188	usher protein
A9237_RS26405	COG2885	chlorophyll binding
A9237_RS26450	COG0561	phosphatase activity
A9237_RS26455	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A9237_RS26460	COG3623	hexulose-6-phosphate isomerase
A9237_RS26495	COG1741	Belongs to the pirin family
A9237_RS26500	COG2259	Doxx family
A9237_RS26510	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A9237_RS26515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A9237_RS26525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A9237_RS26575	COG5001	Diguanylate cyclase
A9237_RS26580	COG4580	involved in the transport of maltose and maltodextrins
A9237_RS26585	COG1609	Transcriptional regulator
A9237_RS26600	COG0395	ABC-type sugar transport system, permease component
A9237_RS26605	COG2723	6-phospho-beta-galactosidase activity
A9237_RS26610	COG3842	ATPase activity
A9237_RS26615	COG1609	Transcriptional regulator
A9237_RS26620	COG0534	Mate efflux family protein
A9237_RS26625	COG0564	pseudouridine synthase activity
A9237_RS26630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A9237_RS26640	COG0561	phosphatase activity
A9237_RS26650	COG2199	diguanylate cyclase activity
A9237_RS26660	COG3152	Membrane
A9237_RS26675	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
A9237_RS26680	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A9237_RS26695	COG0583	DNA-binding transcription factor activity
A9237_RS26730	COG2076	Multidrug Resistance protein
A9237_RS26745	COG1357	PFAM Pentapeptide repeats (8 copies)
A9237_RS26750	COG3047	cAMP biosynthetic process
A9237_RS26755	COG2358	TRAP transporter, solute receptor (TAXI family
A9237_RS26770	COG2814	Major facilitator Superfamily
A9237_RS26790	COG3408	Glycogen debranching enzyme
A9237_RS26790	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
A9237_RS26820	COG0583	DNA-binding transcription factor activity
A9237_RS26860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A9237_RS26900	COG1228	amidohydrolase