locus-tag	class	description
GPY32_RS00005	COG1328	CTP reductase activity
GPY32_RS00020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY32_RS00050	COG0243	molybdopterin cofactor binding
GPY32_RS00060	COG0583	DNA-binding transcription factor activity
GPY32_RS00065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPY32_RS00075	COG2197	response regulator
GPY32_RS00080	COG3851	Histidine kinase
GPY32_RS00085	COG2271	Major facilitator Superfamily
GPY32_RS00110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY32_RS00115	COG3118	belongs to the thioredoxin family
GPY32_RS00120	COG2814	Major facilitator Superfamily
GPY32_RS00130	COG0534	Mate efflux family protein
GPY32_RS00160	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPY32_RS00180	COG2116	formate transmembrane transporter activity
GPY32_RS00185	COG2146	nitrite reductase [NAD(P)H] activity
GPY32_RS00190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPY32_RS00195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY32_RS00235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY32_RS00235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPY32_RS00280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY32_RS00300	COG0277	FAD linked oxidase domain protein
GPY32_RS00305	COG0583	DNA-binding transcription factor activity
GPY32_RS00325	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GPY32_RS00340	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GPY32_RS00355	COG1288	antiporter activity
GPY32_RS00365	COG2814	Major facilitator Superfamily
GPY32_RS00375	COG3040	lipid binding
GPY32_RS00395	COG0419	ATPase involved in DNA repair
GPY32_RS00400	COG0420	3'-5' exonuclease activity
GPY32_RS00415	COG3501	Rhs element vgr protein
GPY32_RS00470	COG0631	protein serine/threonine phosphatase activity
GPY32_RS00505	COG2815	serine threonine protein kinase
GPY32_RS00505	COG0515	serine threonine protein kinase
GPY32_RS00560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPY32_RS00560	COG2146	nitrite reductase [NAD(P)H] activity
GPY32_RS00565	COG1116	anion transmembrane transporter activity
GPY32_RS00570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GPY32_RS00575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GPY32_RS00575	COG1116	anion transmembrane transporter activity
GPY32_RS00585	COG3707	response regulator
GPY32_RS00605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPY32_RS00605	COG1648	precorrin-2 dehydrogenase activity
GPY32_RS00610	COG0243	molybdopterin cofactor binding
GPY32_RS00615	COG0456	acetyltransferase
GPY32_RS00620	COG0814	amino acid
GPY32_RS00630	COG0745	RESPONSE REGULATOR receiver
GPY32_RS00630	COG3706	GGDEF domain
GPY32_RS00650	COG1785	Belongs to the alkaline phosphatase family
GPY32_RS00665	COG0745	RESPONSE REGULATOR receiver
GPY32_RS00685	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GPY32_RS00700	COG1609	Transcriptional regulator
GPY32_RS00705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY32_RS00710	COG1879	ABC-type sugar transport system periplasmic component
GPY32_RS00715	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPY32_RS00720	COG1129	ABC transporter
GPY32_RS00725	COG1869	D-ribose catabolic process
GPY32_RS00730	COG5001	Diguanylate cyclase
GPY32_RS00735	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPY32_RS00795	COG2205	protein histidine kinase activity
GPY32_RS00795	COG0784	Response regulator, receiver
GPY32_RS00815	COG3300	MHYT domain
GPY32_RS00815	COG5001	Diguanylate cyclase
GPY32_RS00825	COG0330	HflC and HflK could
GPY32_RS00840	COG4175	Glycine betaine
GPY32_RS00840	COG0517	IMP dehydrogenase activity
GPY32_RS00845	COG4176	ABC-type proline glycine betaine transport system permease component
GPY32_RS00860	COG1012	belongs to the aldehyde dehydrogenase family
GPY32_RS00865	COG1309	transcriptional regulator
GPY32_RS00870	COG3706	GGDEF domain
GPY32_RS00895	COG1024	Enoyl-CoA hydratase
GPY32_RS00900	COG1960	acyl-CoA dehydrogenase activity
GPY32_RS00910	COG0183	Belongs to the thiolase family
GPY32_RS00920	COG1960	acyl-CoA dehydrogenase activity
GPY32_RS00925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GPY32_RS00935	COG0439	Biotin carboxylase
GPY32_RS00945	COG3850	Histidine kinase
GPY32_RS00945	COG4999	Histidine kinase
GPY32_RS00945	COG3437	response regulator, receiver
GPY32_RS00945	COG2205	protein histidine kinase activity
GPY32_RS00960	COG3264	Mechanosensitive ion channel
GPY32_RS00960	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GPY32_RS00970	COG0110	maltose O-acetyltransferase activity
GPY32_RS00975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY32_RS00980	COG1271	oxidase subunit
GPY32_RS00985	COG1294	oxidase, subunit
GPY32_RS00995	COG0384	phenazine biosynthesis protein PhzF
GPY32_RS01000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPY32_RS01005	COG0789	Transcriptional regulator
GPY32_RS01015	COG3474	cytochrome
GPY32_RS01020	COG1013	pyruvate-flavodoxin oxidoreductase activity
GPY32_RS01025	COG0674	pyruvate-flavodoxin oxidoreductase activity
GPY32_RS01025	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GPY32_RS01095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY32_RS01100	COG0516	GMP reductase activity
GPY32_RS01105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPY32_RS01105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GPY32_RS01120	COG4989	oxidoreductase activity
GPY32_RS01135	COG0038	chloride channel
GPY32_RS01145	COG1914	H( )-stimulated, divalent metal cation uptake system
GPY32_RS01150	COG0302	gtp cyclohydrolase
GPY32_RS01160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY32_RS01180	COG2897	thiosulfate sulfurtransferase activity
GPY32_RS01205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPY32_RS01210	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPY32_RS01215	COG0840	transmembrane signaling receptor activity
GPY32_RS01225	COG2814	Major facilitator Superfamily
GPY32_RS01230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY32_RS01240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY32_RS01250	COG0840	transmembrane signaling receptor activity
GPY32_RS01270	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY32_RS01285	COG2197	response regulator
GPY32_RS01290	COG3850	Histidine kinase
GPY32_RS01295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPY32_RS01305	COG0243	molybdopterin cofactor binding
GPY32_RS01315	COG3005	denitrification pathway
GPY32_RS01335	COG0183	Belongs to the thiolase family
GPY32_RS01355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY32_RS01360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY32_RS01385	COG1522	sequence-specific DNA binding
GPY32_RS01405	COG1566	PFAM secretion protein HlyD family protein
GPY32_RS01415	COG2205	protein histidine kinase activity
GPY32_RS01415	COG0784	Response regulator, receiver
GPY32_RS01420	COG1879	ABC-type sugar transport system periplasmic component
GPY32_RS01425	COG2827	Endonuclease containing a URI domain
GPY32_RS01430	COG3132	Protein of unknown function, DUF480
GPY32_RS01445	COG2926	Belongs to the UPF0265 family
GPY32_RS01450	COG0534	Mate efflux family protein
GPY32_RS01455	COG0673	inositol 2-dehydrogenase activity
GPY32_RS01460	COG0784	Response regulator, receiver
GPY32_RS01460	COG2205	protein histidine kinase activity
GPY32_RS01460	COG5002	protein histidine kinase activity
GPY32_RS01485	COG1522	sequence-specific DNA binding
GPY32_RS01495	COG0531	amino acid
GPY32_RS01510	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GPY32_RS01515	COG2239	Acts as a magnesium transporter
GPY32_RS01525	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GPY32_RS01530	COG0402	S-adenosylhomocysteine deaminase activity
GPY32_RS01540	COG1418	mRNA catabolic process
GPY32_RS01555	COG2814	Major facilitator Superfamily
GPY32_RS01565	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY32_RS01585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY32_RS01605	COG4221	oxidoreductase activity
GPY32_RS01610	COG0745	RESPONSE REGULATOR receiver
GPY32_RS01615	COG2205	protein histidine kinase activity
GPY32_RS01625	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPY32_RS01630	COG2194	sulfuric ester hydrolase activity
GPY32_RS01635	COG0673	inositol 2-dehydrogenase activity
GPY32_RS01660	COG1846	Transcriptional regulator
GPY32_RS01670	COG4667	esterase of the alpha-beta hydrolase superfamily
GPY32_RS01675	COG1741	Belongs to the pirin family
GPY32_RS01680	COG1278	Cold shock
GPY32_RS01700	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPY32_RS01725	COG1686	Belongs to the peptidase S11 family
GPY32_RS01735	COG0625	glutathione transferase activity
GPY32_RS01745	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPY32_RS01770	COG1028	Short-chain dehydrogenase reductase Sdr
GPY32_RS01790	COG3746	phosphate-selective porin O and P
GPY32_RS01810	COG0183	Belongs to the thiolase family
GPY32_RS01890	COG0804	urea catabolic process
GPY32_RS01910	COG0747	negative chemotaxis
GPY32_RS01920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY32_RS01925	COG4172	Belongs to the ABC transporter superfamily
GPY32_RS01935	COG2207	Transcriptional regulator
GPY32_RS01955	COG2916	Histone family protein nucleoid-structuring protein H-NS
GPY32_RS02045	COG4790	Type iii secretion
GPY32_RS02060	COG3710	Transcriptional regulator
GPY32_RS02090	COG4792	protein secretion
GPY32_RS02095	COG4789	Type iii secretion
GPY32_RS02200	COG2199	diguanylate cyclase activity
GPY32_RS02200	COG2200	EAL domain
GPY32_RS02200	COG2202	Pas domain
GPY32_RS02245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPY32_RS02335	COG3833	ABC-type maltose transport systems, permease component
GPY32_RS02340	COG1175	transmembrane transport
GPY32_RS02350	COG3842	ATPase activity
GPY32_RS02415	COG1309	transcriptional regulator
GPY32_RS02420	COG2130	NADP-dependent
GPY32_RS02430	COG0753	catalase activity
GPY32_RS02435	COG2084	Dehydrogenase
GPY32_RS02440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY32_RS02445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY32_RS02455	COG2207	Transcriptional regulator
GPY32_RS02460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY32_RS02460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY32_RS02460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY32_RS02475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY32_RS02480	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GPY32_RS02485	COG3300	MHYT domain
GPY32_RS02485	COG5001	Diguanylate cyclase
GPY32_RS02490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY32_RS02495	COG0569	domain protein
GPY32_RS02505	COG5002	protein histidine kinase activity
GPY32_RS02510	COG1132	(ABC) transporter
GPY32_RS02515	COG4774	siderophore transport
GPY32_RS02520	COG1120	ATPase activity
GPY32_RS02525	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GPY32_RS02575	COG2197	response regulator
GPY32_RS02585	COG0840	transmembrane signaling receptor activity
GPY32_RS02595	COG0714	Associated with various cellular activities
GPY32_RS02615	COG2304	oxidoreductase activity
GPY32_RS02630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY32_RS02635	COG0581	inorganic phosphate transmembrane transporter activity
GPY32_RS02640	COG0573	inorganic phosphate transmembrane transporter activity
GPY32_RS02645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY32_RS02670	COG4771	TonB-dependent receptor
GPY32_RS02675	COG1770	oligopeptidase
GPY32_RS02680	COG0513	Belongs to the DEAD box helicase family
GPY32_RS02690	COG1376	ErfK ybiS ycfS ynhG family protein
GPY32_RS02690	COG1388	LysM domain
GPY32_RS02695	COG0415	Belongs to the DNA photolyase family
GPY32_RS02700	COG0789	Transcriptional regulator
GPY32_RS02705	COG3272	Protein of unknown function (DUF1722)
GPY32_RS02715	COG0813	purine-nucleoside phosphorylase activity
GPY32_RS02730	COG3706	GGDEF domain
GPY32_RS02740	COG1566	PFAM secretion protein HlyD family protein
GPY32_RS02745	COG4720	Psort location CytoplasmicMembrane, score
GPY32_RS02750	COG1122	ATPase activity
GPY32_RS02765	COG0348	domain, Protein
GPY32_RS02770	COG0437	4 iron, 4 sulfur cluster binding
GPY32_RS02775	COG1247	-acetyltransferase
GPY32_RS02805	COG1067	ATP-dependent peptidase activity
GPY32_RS02815	COG4172	Belongs to the ABC transporter superfamily
GPY32_RS02820	COG1505	serine-type exopeptidase activity
GPY32_RS02825	COG0583	DNA-binding transcription factor activity
GPY32_RS02830	COG1620	l-lactate permease
GPY32_RS02835	COG1304	FMN binding
GPY32_RS02845	COG0668	transmembrane transport
GPY32_RS02880	COG1063	alcohol dehydrogenase
GPY32_RS02885	COG0156	8-amino-7-oxononanoate synthase activity
GPY32_RS02895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY32_RS02915	COG0745	RESPONSE REGULATOR receiver
GPY32_RS02950	COG0346	lactoylglutathione lyase activity
GPY32_RS02970	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPY32_RS03010	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY32_RS03025	COG2204	response regulator
GPY32_RS03050	COG1987	bacterial-type flagellum assembly
GPY32_RS03060	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GPY32_RS03075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY32_RS03085	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPY32_RS03090	COG1516	flagellar protein fliS
GPY32_RS03105	COG1580	Controls the rotational direction of flagella during chemotaxis
GPY32_RS03110	COG1191	sigma factor activity
GPY32_RS03115	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPY32_RS03120	COG1360	Flagellar Motor Protein
GPY32_RS03175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY32_RS03180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPY32_RS03190	COG0454	-acetyltransferase
GPY32_RS03205	COG2814	Major facilitator Superfamily
GPY32_RS03250	COG0628	permease
GPY32_RS03255	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPY32_RS03265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY32_RS03275	COG4628	conserved protein (DUF2132)
GPY32_RS03280	COG0583	DNA-binding transcription factor activity
GPY32_RS03305	COG1686	Belongs to the peptidase S11 family
GPY32_RS03325	COG3397	chitin binding
GPY32_RS03330	COG4667	esterase of the alpha-beta hydrolase superfamily
GPY32_RS03335	COG2095	MarC family integral membrane protein
GPY32_RS03355	COG0489	protein tyrosine kinase activity
GPY32_RS03355	COG3206	protein involved in exopolysaccharide biosynthesis
GPY32_RS03370	COG0583	DNA-binding transcription factor activity
GPY32_RS03380	COG1301	dicarboxylic acid transport
GPY32_RS03385	COG3339	Conserved Protein
GPY32_RS03390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY32_RS03395	COG0700	Nucleoside recognition
GPY32_RS03400	COG3366	ferrous iron transmembrane transporter activity
GPY32_RS03415	COG0366	Alpha amylase catalytic
GPY32_RS03420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPY32_RS03425	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GPY32_RS03430	COG1640	4-alpha-glucanotransferase
GPY32_RS03435	COG0058	SHG alpha-glucan phosphorylase activity
GPY32_RS03450	COG2909	trisaccharide binding
GPY32_RS03465	COG1999	signal sequence binding
GPY32_RS03475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY32_RS03475	COG1263	PTS System
GPY32_RS03480	COG1162	GTPase activity
GPY32_RS03485	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GPY32_RS03495	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GPY32_RS03505	COG0531	amino acid
GPY32_RS03510	COG1982	Orn Lys Arg decarboxylase major
GPY32_RS03530	COG2356	endonuclease I
GPY32_RS03555	COG4580	involved in the transport of maltose and maltodextrins
GPY32_RS03580	COG0739	heme binding
GPY32_RS03590	COG0612	Peptidase, M16
GPY32_RS03595	COG0840	transmembrane signaling receptor activity
GPY32_RS03600	COG1120	ATPase activity
GPY32_RS03605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY32_RS03610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY32_RS03615	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GPY32_RS03620	COG4772	TonB-dependent receptor
GPY32_RS03645	COG4264	IucA IucC family
GPY32_RS03650	COG0019	diaminopimelate decarboxylase activity
GPY32_RS03655	COG1653	transport
GPY32_RS03665	COG0745	RESPONSE REGULATOR receiver
GPY32_RS03690	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPY32_RS03695	COG1129	ABC transporter
GPY32_RS03700	COG1879	ABC-type sugar transport system periplasmic component
GPY32_RS03705	COG1069	ribulokinase activity
GPY32_RS03715	COG2160	L-arabinose isomerase activity
GPY32_RS03740	COG1764	response to oxidative stress
GPY32_RS03745	COG1846	Transcriptional regulator
GPY32_RS03750	COG0450	alkyl hydroperoxide reductase
GPY32_RS03755	COG3634	alkyl hydroperoxide reductase activity
GPY32_RS03785	COG1595	DNA-templated transcription, initiation
GPY32_RS03800	COG0840	transmembrane signaling receptor activity
GPY32_RS03805	COG0583	DNA-binding transcription factor activity
GPY32_RS03810	COG1486	melibiose metabolic process
GPY32_RS03825	COG2258	MOSC domain
GPY32_RS03830	COG0513	Belongs to the DEAD box helicase family
GPY32_RS03840	COG2186	Transcriptional regulator
GPY32_RS03850	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GPY32_RS03860	COG0246	Mannitol dehydrogenase
GPY32_RS03865	COG1904	glucuronate isomerase
GPY32_RS03870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY32_RS03875	COG0800	Aldolase
GPY32_RS03900	COG2207	Transcriptional regulator
GPY32_RS03910	COG1132	(ABC) transporter
GPY32_RS03955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY32_RS03985	COG0259	pyridoxamine-phosphate oxidase activity
GPY32_RS04030	COG4166	transmembrane transport
GPY32_RS04050	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPY32_RS04055	COG1263	PTS System
GPY32_RS04055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY32_RS04060	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPY32_RS04065	COG3340	Belongs to the peptidase S51 family
GPY32_RS04085	COG1444	tRNA N-acetyltransferase activity
GPY32_RS04110	COG4608	Belongs to the ABC transporter superfamily
GPY32_RS04115	COG0444	Belongs to the ABC transporter superfamily
GPY32_RS04125	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY32_RS04125	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
GPY32_RS04150	COG0217	transcriptional regulatory protein
GPY32_RS04155	COG0772	Belongs to the SEDS family
GPY32_RS04170	COG1136	(ABC) transporter
GPY32_RS04190	COG3275	phosphorelay sensor kinase activity
GPY32_RS04195	COG3279	Response regulator of the LytR AlgR family
GPY32_RS04205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPY32_RS04240	COG0786	glutamate:sodium symporter activity
GPY32_RS04250	COG1131	(ABC) transporter
GPY32_RS04255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY32_RS04260	COG0786	glutamate:sodium symporter activity
GPY32_RS04275	COG0363	glucosamine-6-phosphate deaminase activity
GPY32_RS04295	COG1741	Belongs to the pirin family
GPY32_RS04300	COG2259	Doxx family
GPY32_RS04315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GPY32_RS04320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPY32_RS04330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPY32_RS04370	COG3123	guanosine phosphorylase activity
GPY32_RS04380	COG5001	Diguanylate cyclase
GPY32_RS04390	COG0534	Mate efflux family protein
GPY32_RS04395	COG0564	pseudouridine synthase activity
GPY32_RS04410	COG0583	DNA-binding transcription factor activity
GPY32_RS04415	COG0561	phosphatase activity
GPY32_RS04425	COG2199	diguanylate cyclase activity
GPY32_RS04440	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GPY32_RS04445	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GPY32_RS04450	COG0583	DNA-binding transcription factor activity
GPY32_RS04465	COG1414	Transcriptional regulator
GPY32_RS04470	COG1028	Short-chain dehydrogenase reductase Sdr
GPY32_RS04480	COG1917	Cupin 2, conserved barrel domain protein
GPY32_RS04495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY32_RS04500	COG0800	Aldolase
GPY32_RS04520	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY32_RS04525	COG0823	Involved in the tonB-independent uptake of proteins
GPY32_RS04530	COG2375	cellular response to nickel ion
GPY32_RS04560	COG1357	PFAM Pentapeptide repeats (8 copies)
GPY32_RS04565	COG3047	cAMP biosynthetic process
GPY32_RS04595	COG3408	Glycogen debranching enzyme
GPY32_RS04595	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GPY32_RS04600	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GPY32_RS04610	COG0583	DNA-binding transcription factor activity
GPY32_RS04620	COG0583	DNA-binding transcription factor activity
GPY32_RS04635	COG0546	phosphoglycolate phosphatase activity
GPY32_RS04660	COG3835	regulator
GPY32_RS04665	COG2610	gluconate transmembrane transporter activity
GPY32_RS04670	COG1929	Belongs to the glycerate kinase type-1 family
GPY32_RS04675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY32_RS04695	COG0454	-acetyltransferase
GPY32_RS04695	COG0456	acetyltransferase
GPY32_RS04710	COG1028	Short-chain dehydrogenase reductase Sdr
GPY32_RS04720	COG3005	denitrification pathway
GPY32_RS04725	COG0243	molybdopterin cofactor binding
GPY32_RS04735	COG0352	thiamine-phosphate diphosphorylase activity
GPY32_RS04740	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GPY32_RS04745	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GPY32_RS04750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GPY32_RS04755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GPY32_RS04760	COG1116	anion transmembrane transporter activity
GPY32_RS04765	COG0351	phosphomethylpyrimidine kinase
GPY32_RS04775	COG0312	modulator of DNA gyrase
GPY32_RS04780	COG0312	modulator of DNA gyrase
GPY32_RS04785	COG1901	pseudouridine methyltransferase
GPY32_RS04845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY32_RS04855	COG0584	glycerophosphoryl diester phosphodiesterase
GPY32_RS04865	COG0745	RESPONSE REGULATOR receiver
GPY32_RS04885	COG0811	peptide transport
GPY32_RS04890	COG0811	peptide transport
GPY32_RS04895	COG0848	biopolymer transport protein
GPY32_RS04940	COG0803	Belongs to the bacterial solute-binding protein 9 family
GPY32_RS04945	COG1121	(ABC) transporter
GPY32_RS04950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPY32_RS04965	COG1770	oligopeptidase
GPY32_RS04970	COG2814	Major facilitator Superfamily
GPY32_RS04975	COG0010	Belongs to the arginase family
GPY32_RS04980	COG1166	arginine decarboxylase activity
GPY32_RS04990	COG4067	protein conserved in archaea
GPY32_RS04990	COG0189	ligase activity
GPY32_RS04995	COG0189	ligase activity
GPY32_RS05000	COG0583	DNA-binding transcription factor activity
GPY32_RS05045	COG3706	GGDEF domain
GPY32_RS05075	COG0579	oxidoreductase
GPY32_RS05085	COG3033	Beta-eliminating lyase
GPY32_RS05105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY32_RS05115	COG3145	DNA-N1-methyladenine dioxygenase activity
GPY32_RS05120	COG3706	GGDEF domain
GPY32_RS05125	COG0840	transmembrane signaling receptor activity
GPY32_RS05140	COG3706	GGDEF domain
GPY32_RS05145	COG0415	Belongs to the DNA photolyase family
GPY32_RS05150	COG3046	protein related to deoxyribodipyrimidine photolyase
GPY32_RS05165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY32_RS05165	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY32_RS05170	COG1765	OsmC-like protein
GPY32_RS05175	COG0110	maltose O-acetyltransferase activity
GPY32_RS05215	COG1011	Hydrolase
GPY32_RS05230	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GPY32_RS05240	COG2067	long-chain fatty acid transport protein
GPY32_RS05245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY32_RS05250	COG0577	efflux transmembrane transporter activity
GPY32_RS05250	COG1136	(ABC) transporter
GPY32_RS05260	COG3240	lipase activity
GPY32_RS05290	COG1609	Transcriptional regulator
GPY32_RS05295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY32_RS05305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPY32_RS05310	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY32_RS05320	COG3842	ATPase activity
GPY32_RS05345	COG2990	Protein conserved in bacteria
GPY32_RS05355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY32_RS05360	COG2866	Carboxypeptidase
GPY32_RS05375	COG0583	DNA-binding transcription factor activity
GPY32_RS05400	COG1760	l-serine dehydratase
GPY32_RS05420	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPY32_RS05430	COG0741	lytic transglycosylase activity
GPY32_RS05450	COG1815	bacterial-type flagellum-dependent cell motility
GPY32_RS05455	COG1558	bacterial-type flagellum-dependent cell motility
GPY32_RS05460	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPY32_RS05465	COG1749	Flagellar hook protein flgE
GPY32_RS05470	COG4787	bacterial-type flagellum-dependent cell motility
GPY32_RS05475	COG4786	Flagellar basal body rod
GPY32_RS05480	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GPY32_RS05485	COG1706	bacterial-type flagellum-dependent cell motility
GPY32_RS05500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY32_RS05520	COG1304	FMN binding
GPY32_RS05550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY32_RS05560	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPY32_RS05565	COG0459	protein refolding
GPY32_RS05580	COG1280	lysine exporter protein (LysE YggA)
GPY32_RS05600	COG1309	transcriptional regulator
GPY32_RS05610	COG0737	Belongs to the 5'-nucleotidase family
GPY32_RS05615	COG2070	2-Nitropropane dioxygenase
GPY32_RS05620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY32_RS05635	COG0346	lactoylglutathione lyase activity
GPY32_RS05640	COG1349	DNA-binding transcription factor activity
GPY32_RS05650	COG0753	catalase activity
GPY32_RS05660	COG1335	isochorismatase
GPY32_RS05670	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPY32_RS05695	COG0583	DNA-binding transcription factor activity
GPY32_RS05710	COG3713	MltA-interacting MipA family protein
GPY32_RS05720	COG3015	lipoprotein NlpE involved in copper resistance
GPY32_RS05730	COG1342	Belongs to the UPF0251 family
GPY32_RS05755	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPY32_RS05765	COG4948	Mandelate Racemase Muconate Lactonizing
GPY32_RS05775	COG0583	DNA-binding transcription factor activity
GPY32_RS05825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPY32_RS05880	COG3842	ATPase activity
GPY32_RS05910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY32_RS05930	COG3706	GGDEF domain
GPY32_RS05950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY32_RS05965	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY32_RS05970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPY32_RS05990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPY32_RS05990	COG0574	Belongs to the PEP-utilizing enzyme family
GPY32_RS05995	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GPY32_RS06000	COG0252	asparaginase activity
GPY32_RS06010	COG0583	DNA-binding transcription factor activity
GPY32_RS06030	COG3122	Protein conserved in bacteria
GPY32_RS06045	COG1028	Short-chain dehydrogenase reductase Sdr
GPY32_RS06055	COG1063	alcohol dehydrogenase
GPY32_RS06060	COG1902	pentaerythritol trinitrate reductase activity
GPY32_RS06075	COG0583	DNA-binding transcription factor activity
GPY32_RS06085	COG0513	Belongs to the DEAD box helicase family
GPY32_RS06130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY32_RS06135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY32_RS06135	COG2207	Transcriptional regulator
GPY32_RS06165	COG2354	Protein conserved in bacteria
GPY32_RS06170	COG0418	dihydroorotase activity
GPY32_RS06180	COG0401	homolog of Blt101
GPY32_RS06190	COG0633	Ferredoxin
GPY32_RS06190	COG3217	Mosc domain protein beta barrel domain protein
GPY32_RS06190	COG0633	Ferredoxin
GPY32_RS06190	COG3217	Mosc domain protein beta barrel domain protein
GPY32_RS06195	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GPY32_RS06200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPY32_RS06240	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GPY32_RS06245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY32_RS06255	COG0848	biopolymer transport protein
GPY32_RS06260	COG0811	peptide transport
GPY32_RS06265	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GPY32_RS06275	COG3721	Heme iron utilization protein
GPY32_RS06280	COG0748	coenzyme F420 binding
GPY32_RS06290	COG0784	Response regulator, receiver
GPY32_RS06290	COG0835	chemotaxis
GPY32_RS06295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY32_RS06310	COG2814	Major facilitator Superfamily
GPY32_RS06345	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GPY32_RS06350	COG0783	Belongs to the Dps family
GPY32_RS06360	COG0583	DNA-binding transcription factor activity
GPY32_RS06375	COG4934	collagen metabolic process
GPY32_RS06385	COG0366	Alpha amylase catalytic
GPY32_RS06405	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPY32_RS06410	COG0589	response to stress
GPY32_RS06415	COG0488	(ABC) transporter
GPY32_RS06420	COG1505	serine-type exopeptidase activity
GPY32_RS06430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY32_RS06440	COG2067	long-chain fatty acid transport protein
GPY32_RS06450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY32_RS06460	COG2203	Gaf domain
GPY32_RS06460	COG2199	diguanylate cyclase activity
GPY32_RS06480	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY32_RS06505	COG3383	formate dehydrogenase (NAD+) activity
GPY32_RS06520	COG0842	Transport permease protein
GPY32_RS06525	COG1131	(ABC) transporter
GPY32_RS06540	COG2706	6-phosphogluconolactonase activity
GPY32_RS06550	COG1881	PFAM PEBP family protein
GPY32_RS06560	COG0798	PFAM Bile acid sodium symporter
GPY32_RS06580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY32_RS06585	COG2213	PTS system mannitol-specific
GPY32_RS06590	COG1063	alcohol dehydrogenase
GPY32_RS06600	COG1072	(Pantothenic acid kinase))
GPY32_RS06605	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPY32_RS06625	COG0814	amino acid
GPY32_RS06665	COG0739	heme binding
GPY32_RS06670	COG5001	Diguanylate cyclase
GPY32_RS06675	COG0583	DNA-binding transcription factor activity
GPY32_RS06680	COG2814	Major facilitator Superfamily
GPY32_RS06705	COG0697	spore germination
GPY32_RS06735	COG2207	Transcriptional regulator
GPY32_RS06740	COG1280	lysine exporter protein (LysE YggA)
GPY32_RS06750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY32_RS06755	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GPY32_RS06765	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GPY32_RS06790	COG1612	heme a metabolic process
GPY32_RS06795	COG0109	protoheme IX farnesyltransferase activity
GPY32_RS06800	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY32_RS06835	COG1278	Cold shock
GPY32_RS06840	COG3036	rescue of stalled ribosome
GPY32_RS06855	COG2199	diguanylate cyclase activity
GPY32_RS06875	COG0577	efflux transmembrane transporter activity
GPY32_RS06875	COG1136	(ABC) transporter
GPY32_RS06885	COG0840	transmembrane signaling receptor activity
GPY32_RS06890	COG0783	Belongs to the Dps family
GPY32_RS06900	COG2133	pyrroloquinoline quinone binding
GPY32_RS06905	COG1454	alcohol dehydrogenase
GPY32_RS06910	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GPY32_RS06945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY32_RS06950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY32_RS06955	COG3186	Phenylalanine-4-hydroxylase
GPY32_RS06960	COG2154	pterin-4-alpha-carbinolamine dehydratase
GPY32_RS06985	COG3530	Putative quorum-sensing-regulated virulence factor
GPY32_RS06990	COG0513	Belongs to the DEAD box helicase family
GPY32_RS06995	COG4628	conserved protein (DUF2132)
GPY32_RS07000	COG0133	tryptophan synthase activity
GPY32_RS07010	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GPY32_RS07020	COG0523	cobalamin synthesis protein
GPY32_RS07025	COG0513	Belongs to the DEAD box helicase family
GPY32_RS07045	COG2200	EAL domain
GPY32_RS07050	COG1119	ATPase activity
GPY32_RS07055	COG0840	transmembrane signaling receptor activity
GPY32_RS07080	COG0641	radical SAM
GPY32_RS07100	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY32_RS07115	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GPY32_RS07120	COG0513	Belongs to the DEAD box helicase family
GPY32_RS07125	COG5001	Diguanylate cyclase
GPY32_RS07135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPY32_RS07150	COG5413	integral membrane protein
GPY32_RS07160	COG1024	Enoyl-CoA hydratase
GPY32_RS07165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GPY32_RS07170	COG1960	acyl-CoA dehydrogenase activity
GPY32_RS07180	COG0183	Belongs to the thiolase family
GPY32_RS07195	COG1024	Enoyl-CoA hydratase
GPY32_RS07200	COG1024	Enoyl-CoA hydratase
GPY32_RS07210	COG1028	Short-chain dehydrogenase reductase Sdr
GPY32_RS07215	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GPY32_RS07220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPY32_RS07225	COG1845	cytochrome c oxidase, subunit III
GPY32_RS07230	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GPY32_RS07235	COG0109	protoheme IX farnesyltransferase activity
GPY32_RS07240	COG1902	pentaerythritol trinitrate reductase activity
GPY32_RS07250	COG1126	abc transporter atp-binding protein
GPY32_RS07255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY32_RS07260	COG4215	(ABC) transporter
GPY32_RS07265	COG4160	amino acid transport
GPY32_RS07280	COG0625	glutathione transferase activity
GPY32_RS07315	COG0443	Heat shock 70 kDa protein
GPY32_RS07320	COG2847	Copper chaperone PCu(A)C
GPY32_RS07345	COG4607	ABC-type enterochelin transport system periplasmic component
GPY32_RS07350	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY32_RS07355	COG4605	iron ion homeostasis
GPY32_RS07360	COG4604	ABC transporter, ATP-binding protein
GPY32_RS07365	COG0789	Transcriptional regulator
GPY32_RS07380	COG4771	TonB-dependent receptor
GPY32_RS07380	COG1629	transport
GPY32_RS07415	COG1289	transmembrane transporter activity
GPY32_RS07420	COG0210	DNA helicase
GPY32_RS07425	COG1803	Methylglyoxal synthase
GPY32_RS07430	COG1879	ABC-type sugar transport system periplasmic component
GPY32_RS07435	COG2205	protein histidine kinase activity
GPY32_RS07435	COG2198	Histidine kinase
GPY32_RS07435	COG0784	Response regulator, receiver
GPY32_RS07450	COG0745	RESPONSE REGULATOR receiver
GPY32_RS07455	COG3119	arylsulfatase activity
GPY32_RS07460	COG3119	arylsulfatase activity
GPY32_RS07475	COG3119	arylsulfatase activity
GPY32_RS07480	COG0641	radical SAM
GPY32_RS07485	COG0714	Associated with various cellular activities
GPY32_RS07515	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY32_RS07515	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY32_RS07520	COG0583	DNA-binding transcription factor activity
GPY32_RS07525	COG1597	lipid kinase activity
GPY32_RS07530	COG3111	PFAM Bacterial OB fold (BOF) protein
GPY32_RS07550	COG0641	radical SAM
GPY32_RS07580	COG0501	Belongs to the peptidase M48B family
GPY32_RS07585	COG1704	LemA family
GPY32_RS07590	COG3069	C4-dicarboxylate transmembrane transporter activity
GPY32_RS07600	COG0456	acetyltransferase
GPY32_RS07600	COG1214	PFAM Peptidase M22, glycoprotease
GPY32_RS07620	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPY32_RS07640	COG2207	Transcriptional regulator
GPY32_RS07665	COG4964	Belongs to the GSP D family
GPY32_RS07725	COG0583	DNA-binding transcription factor activity
GPY32_RS07730	COG0583	DNA-binding transcription factor activity
GPY32_RS07745	COG5001	Diguanylate cyclase
GPY32_RS07745	COG3300	MHYT domain
GPY32_RS07750	COG2197	response regulator
GPY32_RS07755	COG3706	GGDEF domain
GPY32_RS07765	COG2197	response regulator
GPY32_RS07790	COG0784	Response regulator, receiver
GPY32_RS07790	COG0835	chemotaxis
GPY32_RS07810	COG2962	Rard protein
GPY32_RS07825	COG0671	phosphoesterase, PA-phosphatase related
GPY32_RS07840	COG2076	Multidrug Resistance protein
GPY32_RS07870	COG0471	metal ion transport
GPY32_RS07875	COG3290	protein histidine kinase activity
GPY32_RS07880	COG4565	transcriptional regulatory protein
GPY32_RS07890	COG0069	glutamate synthase activity
GPY32_RS07890	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GPY32_RS07900	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GPY32_RS07925	COG1902	pentaerythritol trinitrate reductase activity
GPY32_RS07930	COG0346	lactoylglutathione lyase activity
GPY32_RS07950	COG2239	Acts as a magnesium transporter
GPY32_RS07980	COG0242	peptide deformylase activity
GPY32_RS08025	COG2176	DNA-directed DNA polymerase activity
GPY32_RS08030	COG0583	DNA-binding transcription factor activity
GPY32_RS08035	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPY32_RS08040	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GPY32_RS08055	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPY32_RS08055	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPY32_RS08060	COG0509	glycine decarboxylation via glycine cleavage system
GPY32_RS08065	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPY32_RS08105	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GPY32_RS08105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY32_RS08105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY32_RS08110	COG1105	Belongs to the carbohydrate kinase PfkB family
GPY32_RS08115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY32_RS08115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY32_RS08120	COG1609	Transcriptional regulator
GPY32_RS08140	COG2200	EAL domain
GPY32_RS08140	COG2199	diguanylate cyclase activity
GPY32_RS08140	COG2203	Gaf domain
GPY32_RS08145	COG0765	amino acid transport
GPY32_RS08150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY32_RS08155	COG0765	amino acid transport
GPY32_RS08160	COG1126	abc transporter atp-binding protein
GPY32_RS08165	COG0469	pyruvate kinase activity
GPY32_RS08170	COG2271	Major facilitator Superfamily
GPY32_RS08175	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY32_RS08195	COG1979	alcohol dehydrogenase
GPY32_RS08200	COG2207	Transcriptional regulator
GPY32_RS08215	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPY32_RS08220	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GPY32_RS08225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY32_RS08245	COG3437	response regulator, receiver
GPY32_RS08245	COG0784	Response regulator, receiver
GPY32_RS08255	COG0546	phosphoglycolate phosphatase activity
GPY32_RS08260	COG0840	transmembrane signaling receptor activity
GPY32_RS08270	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GPY32_RS08275	COG0513	Belongs to the DEAD box helicase family
GPY32_RS08280	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GPY32_RS08295	COG3038	cytochrome b561
GPY32_RS08300	COG2353	YceI-like domain
GPY32_RS08305	COG2116	formate transmembrane transporter activity
GPY32_RS08310	COG0583	DNA-binding transcription factor activity
GPY32_RS08320	COG3593	DNA synthesis involved in DNA repair
GPY32_RS08325	COG0737	Belongs to the 5'-nucleotidase family
GPY32_RS08330	COG0861	Integral membrane protein TerC family
GPY32_RS08345	COG1943	Transposase
GPY32_RS08350	COG2267	carboxylic ester hydrolase activity
GPY32_RS08355	COG2067	long-chain fatty acid transport protein
GPY32_RS08370	COG2050	protein possibly involved in aromatic compounds catabolism
GPY32_RS08380	COG4533	DNA binding
GPY32_RS08405	COG0484	heat shock protein binding
GPY32_RS08415	COG3300	MHYT domain
GPY32_RS08415	COG5001	Diguanylate cyclase
GPY32_RS08420	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPY32_RS08430	COG4181	ATPase activity
GPY32_RS08435	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GPY32_RS08445	COG1984	allophanate hydrolase subunit 2
GPY32_RS08450	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GPY32_RS08455	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GPY32_RS08460	COG5002	protein histidine kinase activity
GPY32_RS08460	COG3447	MASE1 domain protein
GPY32_RS08460	COG5001	Diguanylate cyclase
GPY32_RS08465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPY32_RS08475	COG1629	transport
GPY32_RS08475	COG4771	TonB-dependent receptor
GPY32_RS08480	COG0583	DNA-binding transcription factor activity
GPY32_RS08485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY32_RS08485	COG1042	CoA-binding domain protein
GPY32_RS08485	COG0045	succinate-CoA ligase (ADP-forming) activity
GPY32_RS08495	COG1181	Belongs to the D-alanine--D-alanine ligase family
GPY32_RS08505	COG0023	Translation Initiation Factor
GPY32_RS08520	COG0589	response to stress
GPY32_RS08525	COG3140	Belongs to the UPF0181 family
GPY32_RS08550	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GPY32_RS08555	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GPY32_RS08570	COG0745	RESPONSE REGULATOR receiver
GPY32_RS08570	COG3706	GGDEF domain
GPY32_RS08580	COG2203	Gaf domain
GPY32_RS08580	COG5001	Diguanylate cyclase
GPY32_RS08580	COG3706	GGDEF domain
GPY32_RS08580	COG4251	negative regulation of phosphorylation
GPY32_RS08590	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GPY32_RS08595	COG4149	molybdate abc transporter
GPY32_RS08600	COG0725	ABC transporter, periplasmic molybdate-binding protein
GPY32_RS08605	COG1492	cobalamin metabolic process
GPY32_RS08610	COG3111	PFAM Bacterial OB fold (BOF) protein
GPY32_RS08620	COG0189	ligase activity
GPY32_RS08620	COG4067	protein conserved in archaea
GPY32_RS08640	COG0534	Mate efflux family protein
GPY32_RS08645	COG0602	queuosine metabolic process
GPY32_RS08690	COG4608	Belongs to the ABC transporter superfamily
GPY32_RS08695	COG0444	Belongs to the ABC transporter superfamily
GPY32_RS08700	COG0747	negative chemotaxis
GPY32_RS08705	COG4239	(ABC) transporter, permease
GPY32_RS08710	COG4174	ABC transporter (Permease)
GPY32_RS08735	COG0811	peptide transport
GPY32_RS08740	COG0848	biopolymer transport protein
GPY32_RS08755	COG0194	GDP metabolic process
GPY32_RS08760	COG1758	RNA polymerase activity
GPY32_RS08765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY32_RS08770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY32_RS08775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPY32_RS08780	COG2233	PERMEase
GPY32_RS08785	COG2205	protein histidine kinase activity
GPY32_RS08790	COG0745	RESPONSE REGULATOR receiver
GPY32_RS08800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY32_RS08810	COG2183	response to ionizing radiation
GPY32_RS08820	COG0596	Alpha beta hydrolase
GPY32_RS08825	COG1040	competence protein
GPY32_RS08830	COG0316	Belongs to the HesB IscA family
GPY32_RS08830	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GPY32_RS08835	COG0494	nUDIX hydrolase
GPY32_RS08840	COG1218	3'(2'),5'-bisphosphate nucleotidase
GPY32_RS08850	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPY32_RS08855	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPY32_RS08860	COG3156	type II secretion system protein K
GPY32_RS08865	COG4795	General secretion pathway protein
GPY32_RS08870	COG2165	general secretion pathway protein
GPY32_RS08875	COG2165	general secretion pathway protein
GPY32_RS08880	COG2165	general secretion pathway protein
GPY32_RS08885	COG1459	type II secretion system
GPY32_RS08890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY32_RS08900	COG3031	protein transport across the cell outer membrane
GPY32_RS08905	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GPY32_RS08910	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPY32_RS08915	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GPY32_RS08925	COG0456	acetyltransferase
GPY32_RS08930	COG1490	D-aminoacyl-tRNA deacylase activity
GPY32_RS08935	COG1295	ribonuclease BN
GPY32_RS08955	COG0174	glutamine synthetase
GPY32_RS08965	COG3852	Histidine kinase
GPY32_RS08970	COG2204	response regulator
GPY32_RS08980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPY32_RS08985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY32_RS09015	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GPY32_RS09025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY32_RS09025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY32_RS09050	COG0084	hydrolase, TatD family'
GPY32_RS09060	COG0805	protein transport
GPY32_RS09070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPY32_RS09075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GPY32_RS09080	COG3165	ubiquinone biosynthetic process from chorismate
GPY32_RS09085	COG2226	methyltransferase
GPY32_RS09090	COG1322	Protein conserved in bacteria
GPY32_RS09105	COG0628	permease
GPY32_RS09155	COG2823	Periplasmic or secreted lipoprotein
GPY32_RS09165	COG2081	HI0933 family
GPY32_RS09175	COG1528	Iron-storage protein
GPY32_RS09180	COG0589	response to stress
GPY32_RS09185	COG0697	spore germination
GPY32_RS09195	COG0742	ribosomal rna small subunit methyltransferase
GPY32_RS09200	COG5002	protein histidine kinase activity
GPY32_RS09200	COG5001	Diguanylate cyclase
GPY32_RS09205	COG1522	sequence-specific DNA binding
GPY32_RS09210	COG0339	signal peptide processing
GPY32_RS09215	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GPY32_RS09220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY32_RS09225	COG0583	DNA-binding transcription factor activity
GPY32_RS09230	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GPY32_RS09235	COG0800	Aldolase
GPY32_RS09240	COG2610	gluconate transmembrane transporter activity
GPY32_RS09245	COG3265	gluconokinase activity
GPY32_RS09250	COG0129	dihydroxy-acid dehydratase activity
GPY32_RS09255	COG2076	Multidrug Resistance protein
GPY32_RS09265	COG0583	DNA-binding transcription factor activity
GPY32_RS09270	COG1609	Transcriptional regulator
GPY32_RS09310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY32_RS09320	COG0747	negative chemotaxis
GPY32_RS09325	COG4172	Belongs to the ABC transporter superfamily
GPY32_RS09390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY32_RS09395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY32_RS09405	COG2960	long-chain fatty acid transporting porin activity
GPY32_RS09410	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPY32_RS09415	COG0583	DNA-binding transcription factor activity
GPY32_RS09450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPY32_RS09460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPY32_RS09465	COG0408	coproporphyrinogen oxidase activity
GPY32_RS09470	COG0009	L-threonylcarbamoyladenylate synthase
GPY32_RS09475	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPY32_RS09480	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPY32_RS09485	COG0551	DNA topoisomerase type I activity
GPY32_RS09490	COG2922	Belongs to the Smg family
GPY32_RS09495	COG0758	DNA mediated transformation
GPY32_RS09505	COG0242	peptide deformylase activity
GPY32_RS09510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPY32_RS09515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPY32_RS09515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPY32_RS09520	COG0569	domain protein
GPY32_RS09525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY32_RS09535	COG1272	protein, Hemolysin III
GPY32_RS09540	COG4326	sporulation control protein
GPY32_RS09550	COG3084	Protein conserved in bacteria
GPY32_RS09560	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPY32_RS09565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY32_RS09570	COG0204	Acyl-transferase
GPY32_RS09580	COG0606	chelatase, subunit chli
GPY32_RS09590	COG3978	acetolactate synthase activity
GPY32_RS09595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPY32_RS09600	COG0129	dihydroxy-acid dehydratase activity
GPY32_RS09610	COG0583	DNA-binding transcription factor activity
GPY32_RS09615	COG2814	Major facilitator Superfamily
GPY32_RS09620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY32_RS09625	COG0765	amino acid transport
GPY32_RS09630	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPY32_RS09635	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GPY32_RS09640	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPY32_RS09645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPY32_RS09650	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPY32_RS09655	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPY32_RS09670	COG0356	it plays a direct role in the translocation of protons across the membrane
GPY32_RS09675	COG3312	ion transport
GPY32_RS09680	COG1475	DNA binding
GPY32_RS09685	COG1192	Involved in chromosome partitioning
GPY32_RS09690	COG0357	Ribosomal RNA small subunit methyltransferase G
GPY32_RS09695	COG0445	tRNA wobble uridine modification
GPY32_RS09700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY32_RS09750	COG3645	SOS response
GPY32_RS09755	COG3645	SOS response
GPY32_RS09765	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GPY32_RS09800	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPY32_RS09805	COG0706	membrane insertase activity
GPY32_RS09810	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GPY32_RS09815	COG0594	ribonuclease P activity
GPY32_RS09825	COG1126	abc transporter atp-binding protein
GPY32_RS09850	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPY32_RS09855	COG0592	DNA-directed DNA polymerase activity
GPY32_RS09860	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPY32_RS09865	COG0187	DNA topoisomerase II activity
GPY32_RS09885	COG0071	Belongs to the small heat shock protein (HSP20) family
GPY32_RS09890	COG3977	Valine--pyruvate aminotransferase
GPY32_RS09895	COG0366	Alpha amylase catalytic
GPY32_RS09900	COG0751	glycine-tRNA ligase activity
GPY32_RS09905	COG0752	glycyl-tRNA synthetase alpha subunit
GPY32_RS09910	COG2119	membrane
GPY32_RS09920	COG0425	Belongs to the sulfur carrier protein TusA family
GPY32_RS09935	COG0604	alcohol dehydrogenase
GPY32_RS09940	COG0183	Belongs to the thiolase family
GPY32_RS09945	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPY32_RS09945	COG1024	Enoyl-CoA hydratase
GPY32_RS09950	COG1739	Uncharacterized protein family UPF0029
GPY32_RS09955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY32_RS10035	COG3335	DDE superfamily endonuclease
GPY32_RS10040	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPY32_RS10045	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GPY32_RS10050	COG0352	thiamine-phosphate diphosphorylase activity
GPY32_RS10055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY32_RS10060	COG2104	thiamine diphosphate biosynthetic process
GPY32_RS10065	COG2022	thiamine diphosphate biosynthetic process
GPY32_RS10075	COG0006	proline dipeptidase activity
GPY32_RS10075	COG0006	proline dipeptidase activity
GPY32_RS10105	COG3220	belongs to the UPF0276 family
GPY32_RS10115	COG0210	DNA helicase
GPY32_RS10125	COG0405	Gamma-glutamyltransferase
GPY32_RS10130	COG1280	lysine exporter protein (LysE YggA)
GPY32_RS10140	COG2962	Rard protein
GPY32_RS10145	COG0514	ATP-dependent DNA helicase (RecQ)
GPY32_RS10160	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPY32_RS10165	COG0248	Ppx GppA phosphatase
GPY32_RS10170	COG0513	Belongs to the DEAD box helicase family
GPY32_RS10175	COG3118	belongs to the thioredoxin family
GPY32_RS10180	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPY32_RS10195	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GPY32_RS10200	COG0633	Ferredoxin
GPY32_RS10250	COG3071	HemY protein
GPY32_RS10255	COG2959	enzyme of heme biosynthesis
GPY32_RS10260	COG1587	Uroporphyrinogen-III synthase
GPY32_RS10265	COG0181	hydroxymethylbilane synthase activity
GPY32_RS10270	COG3072	Adenylate cyclase
GPY32_RS10275	COG1965	Belongs to the frataxin family
GPY32_RS10285	COG0019	diaminopimelate decarboxylase activity
GPY32_RS10290	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPY32_RS10300	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GPY32_RS10305	COG1011	Hydrolase
GPY32_RS10310	COG3287	FIST C domain
GPY32_RS10310	COG2199	diguanylate cyclase activity
GPY32_RS10310	COG2200	EAL domain
GPY32_RS10330	COG0561	phosphatase activity
GPY32_RS10335	COG2267	carboxylic ester hydrolase activity
GPY32_RS10340	COG1280	lysine exporter protein (LysE YggA)
GPY32_RS10345	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY32_RS10350	COG0640	Transcriptional regulator
GPY32_RS10355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY32_RS10410	COG2095	MarC family integral membrane protein
GPY32_RS10420	COG0742	ribosomal rna small subunit methyltransferase
GPY32_RS10425	COG0552	protein localization to endoplasmic reticulum
GPY32_RS10430	COG2884	Cell division ATP-binding protein ftsE
GPY32_RS10435	COG2177	Part of the ABC transporter FtsEX involved in
GPY32_RS10445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY32_RS10450	COG0705	Rhomboid family
GPY32_RS10455	COG1580	Controls the rotational direction of flagella during chemotaxis
GPY32_RS10460	COG3161	chorismate lyase activity
GPY32_RS10465	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GPY32_RS10470	COG2937	Belongs to the GPAT DAPAT family
GPY32_RS10480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPY32_RS10485	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GPY32_RS10490	COG0534	Mate efflux family protein
GPY32_RS10495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY32_RS10510	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY32_RS10515	COG4206	TonB-dependent receptor
GPY32_RS10525	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GPY32_RS10555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPY32_RS10565	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GPY32_RS10600	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPY32_RS10610	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY32_RS10615	COG0250	Participates in transcription elongation, termination and antitermination
GPY32_RS10620	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPY32_RS10625	COG0081	regulation of translation
GPY32_RS10630	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPY32_RS10635	COG0222	ribosome binding
GPY32_RS10640	COG0085	RNA polymerase activity
GPY32_RS10645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPY32_RS10650	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GPY32_RS10655	COG2816	NAD+ diphosphatase activity
GPY32_RS10670	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GPY32_RS10675	COG1573	uracil-dna glycosylase
GPY32_RS10680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY32_RS10685	COG3068	Protein conserved in bacteria
GPY32_RS10690	COG1253	flavin adenine dinucleotide binding
GPY32_RS10705	COG0151	Belongs to the GarS family
GPY32_RS10715	COG0138	bifunctional purine biosynthesis protein purh
GPY32_RS10725	COG0789	Transcriptional regulator
GPY32_RS10730	COG3710	Transcriptional regulator
GPY32_RS10740	COG0531	amino acid
GPY32_RS10745	COG1982	Orn Lys Arg decarboxylase major
GPY32_RS10810	COG3706	GGDEF domain
GPY32_RS10815	COG0488	(ABC) transporter
GPY32_RS10820	COG2814	Major facilitator Superfamily
GPY32_RS10825	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GPY32_RS10830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY32_RS10835	COG2264	protein methyltransferase activity
GPY32_RS10845	COG0439	Biotin carboxylase
GPY32_RS10850	COG0511	ligase activity, forming carbon-carbon bonds
GPY32_RS10855	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GPY32_RS10860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY32_RS10875	COG2814	Major facilitator Superfamily
GPY32_RS10880	COG0784	Response regulator, receiver
GPY32_RS10880	COG2205	protein histidine kinase activity
GPY32_RS10905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY32_RS10915	COG3263	regulation of cellular component size
GPY32_RS10925	COG4232	protein-disulfide reductase activity
GPY32_RS10930	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPY32_RS10935	COG1027	Aspartate ammonia-lyase
GPY32_RS10940	COG3030	protein affecting phage T7 exclusion by the F plasmid
GPY32_RS10945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GPY32_RS10955	COG2205	protein histidine kinase activity
GPY32_RS10960	COG0745	RESPONSE REGULATOR receiver
GPY32_RS10965	COG3678	ATP-independent chaperone mediated protein folding
GPY32_RS10975	COG0205	6-phosphofructokinase activity
GPY32_RS10980	COG0534	Mate efflux family protein
GPY32_RS10985	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPY32_RS10990	COG0459	protein refolding
GPY32_RS11005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY32_RS11015	COG1509	lysine 2,3-aminomutase activity
GPY32_RS11020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPY32_RS11030	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPY32_RS11035	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPY32_RS11040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPY32_RS11045	COG1053	succinate dehydrogenase
GPY32_RS11055	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GPY32_RS11075	COG4942	peptidase
GPY32_RS11080	COG1045	serine acetyltransferase
GPY32_RS11085	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GPY32_RS11090	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GPY32_RS11095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY32_RS11100	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPY32_RS11115	COG0471	metal ion transport
GPY32_RS11120	COG0688	phosphatidylethanolamine metabolic process
GPY32_RS11125	COG1162	GTPase activity
GPY32_RS11130	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GPY32_RS11200	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPY32_RS11205	COG0802	atpase or kinase
GPY32_RS11210	COG0860	N-Acetylmuramoyl-L-alanine amidase
GPY32_RS11215	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPY32_RS11220	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPY32_RS11230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPY32_RS11235	COG0330	HflC and HflK could
GPY32_RS11240	COG0330	HflC and HflK could
GPY32_RS11245	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GPY32_RS11250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPY32_RS11260	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GPY32_RS11265	COG1017	nitric oxide dioxygenase activity
GPY32_RS11265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY32_RS11270	COG1959	2 iron, 2 sulfur cluster binding
GPY32_RS11275	COG0557	exoribonuclease II activity
GPY32_RS11280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY32_RS11285	COG0546	phosphoglycolate phosphatase activity
GPY32_RS11290	COG0180	Tryptophanyl-tRNA synthetase
GPY32_RS11320	COG0512	Glutamine amidotransferase of anthranilate synthase
GPY32_RS11325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPY32_RS11335	COG1012	belongs to the aldehyde dehydrogenase family
GPY32_RS11345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY32_RS11350	COG3954	Phosphoribulokinase
GPY32_RS11355	COG3089	Belongs to the UPF0270 family
GPY32_RS11360	COG0429	hydrolase of the alpha beta-hydrolase fold
GPY32_RS11370	COG0488	(ABC) transporter
GPY32_RS11380	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPY32_RS11395	COG1047	Peptidyl-prolyl cis-trans
GPY32_RS11405	COG1446	asparaginase
GPY32_RS11410	COG2900	Belongs to the SlyX family
GPY32_RS11420	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY32_RS11425	COG2964	Protein conserved in bacteria
GPY32_RS11430	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GPY32_RS11435	COG2923	Belongs to the DsrF TusC family
GPY32_RS11440	COG2168	tRNA wobble position uridine thiolation
GPY32_RS11450	COG0049	tRNA binding
GPY32_RS11455	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPY32_RS11460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPY32_RS11465	COG2906	2 iron, 2 sulfur cluster binding
GPY32_RS11475	COG0281	malic enzyme
GPY32_RS11485	COG0626	cystathionine gamma-synthase activity
GPY32_RS11490	COG0527	aspartate kinase activity
GPY32_RS11490	COG0460	homoserine dehydrogenase
GPY32_RS11495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPY32_RS11500	COG1695	Transcriptional regulator
GPY32_RS11505	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GPY32_RS11510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY32_RS11515	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPY32_RS11520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPY32_RS11525	COG0137	argininosuccinate synthase activity
GPY32_RS11530	COG0165	Argininosuccinate lyase
GPY32_RS11530	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPY32_RS11545	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY32_RS11545	COG0678	peroxiredoxin activity
GPY32_RS11555	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GPY32_RS11585	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GPY32_RS11590	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPY32_RS11600	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GPY32_RS11605	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPY32_RS11610	COG0360	Binds together with S18 to 16S ribosomal RNA
GPY32_RS11615	COG2965	DNA replication, synthesis of RNA primer
GPY32_RS11625	COG0359	binds to the 23S rRNA
GPY32_RS11635	COG0305	Participates in initiation and elongation during chromosome replication
GPY32_RS11640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY32_RS11650	COG0432	Pfam Uncharacterised protein family UPF0047
GPY32_RS11655	COG0166	Belongs to the GPI family
GPY32_RS11665	COG0735	belongs to the Fur family
GPY32_RS11675	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY32_RS11700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY32_RS11705	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPY32_RS11710	COG0175	sulfate reduction
GPY32_RS11785	COG0646	methionine synthase
GPY32_RS11785	COG1410	methionine synthase
GPY32_RS11790	COG0527	aspartate kinase activity
GPY32_RS11795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPY32_RS11805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPY32_RS11820	COG0629	single-stranded DNA binding
GPY32_RS11825	COG2199	diguanylate cyclase activity
GPY32_RS11825	COG2200	EAL domain
GPY32_RS11850	COG3267	Type II secretory pathway component ExeA
GPY32_RS11850	COG3409	Peptidoglycan-binding domain 1 protein
GPY32_RS11860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY32_RS11865	COG1459	type II secretion system
GPY32_RS11910	COG1077	Cell shape determining protein MreB Mrl
GPY32_RS11915	COG1792	Involved in formation and maintenance of cell shape
GPY32_RS11920	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GPY32_RS11925	COG0424	maF-like protein
GPY32_RS11930	COG1530	ribonuclease E activity
GPY32_RS11935	COG3164	Protein of unknown function
GPY32_RS11940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPY32_RS11945	COG0312	modulator of DNA gyrase
GPY32_RS11950	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GPY32_RS11955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GPY32_RS11970	COG0564	pseudouridine synthase activity
GPY32_RS11975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY32_RS11980	COG3028	Belongs to the UPF0307 family
GPY32_RS11985	COG0312	modulator of DNA gyrase
GPY32_RS11990	COG2239	Acts as a magnesium transporter
GPY32_RS11995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY32_RS12000	COG1660	Displays ATPase and GTPase activities
GPY32_RS12005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY32_RS12010	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY32_RS12020	COG1137	ATPase activity
GPY32_RS12025	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GPY32_RS12035	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GPY32_RS12035	COG0517	IMP dehydrogenase activity
GPY32_RS12045	COG1127	ABC transporter
GPY32_RS12050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GPY32_RS12055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPY32_RS12060	COG2854	intermembrane phospholipid transfer
GPY32_RS12070	COG5007	Belongs to the BolA IbaG family
GPY32_RS12075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPY32_RS12080	COG0204	Acyl-transferase
GPY32_RS12085	COG0251	oxidation-reduction process
GPY32_RS12090	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GPY32_RS12095	COG0540	Belongs to the ATCase OTCase family
GPY32_RS12105	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPY32_RS12110	COG2235	arginine
GPY32_RS12140	COG0525	valine-tRNA ligase activity
GPY32_RS12145	COG2927	DNA polymerase III (CHI subunit)
GPY32_RS12150	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPY32_RS12155	COG0795	lipopolysaccharide-transporting ATPase activity
GPY32_RS12160	COG0795	lipopolysaccharide-transporting ATPase activity
GPY32_RS12170	COG4325	translation initiation factor activity
GPY32_RS12185	COG0726	polysaccharide deacetylase
GPY32_RS12190	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPY32_RS12195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPY32_RS12200	COG1447	Phosphotransferase system cellobiose-specific component IIA
GPY32_RS12205	COG1486	melibiose metabolic process
GPY32_RS12210	COG3394	polysaccharide catabolic process
GPY32_RS12220	COG3437	response regulator, receiver
GPY32_RS12270	COG1012	belongs to the aldehyde dehydrogenase family
GPY32_RS12340	COG0741	lytic transglycosylase activity
GPY32_RS12345	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GPY32_RS12355	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GPY32_RS12365	COG2066	Belongs to the glutaminase family
GPY32_RS12370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY32_RS12375	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPY32_RS12385	COG1872	DUF167
GPY32_RS12390	COG0762	integral membrane protein
GPY32_RS12395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPY32_RS12400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPY32_RS12415	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPY32_RS12420	COG1678	Uncharacterized ACR, COG1678
GPY32_RS12425	COG0189	ligase activity
GPY32_RS12430	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GPY32_RS12435	COG2356	endonuclease I
GPY32_RS12440	COG3091	SprT-like family
GPY32_RS12450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPY32_RS12460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPY32_RS12465	COG0583	DNA-binding transcription factor activity
GPY32_RS12470	COG4771	TonB-dependent receptor
GPY32_RS12475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY32_RS12480	COG0126	phosphoglycerate kinase activity
GPY32_RS12485	COG0191	fructose-bisphosphate aldolase activity
GPY32_RS12490	COG0668	transmembrane transport
GPY32_RS12495	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPY32_RS12505	COG0583	DNA-binding transcription factor activity
GPY32_RS12515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY32_RS12520	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GPY32_RS12525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPY32_RS12535	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPY32_RS12545	COG3079	Belongs to the UPF0149 family
GPY32_RS12550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY32_RS12555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY32_RS12570	COG0354	folic acid binding
GPY32_RS12575	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GPY32_RS12585	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GPY32_RS12595	COG1595	DNA-templated transcription, initiation
GPY32_RS12600	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GPY32_RS12610	COG3086	response to oxidative stress
GPY32_RS12615	COG0481	GTPase activity
GPY32_RS12620	COG0681	Belongs to the peptidase S26 family
GPY32_RS12625	COG0571	ribonuclease III activity
GPY32_RS12630	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPY32_RS12635	COG1381	Involved in DNA repair and RecF pathway recombination
GPY32_RS12640	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GPY32_RS12645	COG0736	holo-[acyl-carrier-protein] synthase activity
GPY32_RS12655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY32_RS12665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY32_RS12670	COG3956	TIGRFAM MazG family protein
GPY32_RS12675	COG0504	CTP synthase activity
GPY32_RS12680	COG0148	phosphopyruvate hydratase activity
GPY32_RS12685	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GPY32_RS12690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPY32_RS12695	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GPY32_RS12700	COG0585	pseudouridine synthase activity
GPY32_RS12705	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GPY32_RS12710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GPY32_RS12725	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPY32_RS12730	COG1546	Belongs to the CinA family
GPY32_RS12735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPY32_RS12740	COG2137	regulation of response to DNA damage stimulus
GPY32_RS12745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPY32_RS12750	COG0527	aspartate kinase activity
GPY32_RS12810	COG3630	sodium ion export across plasma membrane
GPY32_RS12815	COG0511	ligase activity, forming carbon-carbon bonds
GPY32_RS12815	COG5016	pyruvate
GPY32_RS12820	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPY32_RS12825	COG1063	alcohol dehydrogenase
GPY32_RS12830	COG1238	metal cluster binding
GPY32_RS12835	COG0612	Peptidase, M16
GPY32_RS12840	COG2918	glutathione biosynthetic process
GPY32_RS12850	COG1854	S-ribosylhomocysteine lyase activity
GPY32_RS12855	COG4536	flavin adenine dinucleotide binding
GPY32_RS12860	COG4137	Cytochrome C assembly protein
GPY32_RS12865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPY32_RS12870	COG0228	four-way junction DNA binding
GPY32_RS12875	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPY32_RS12880	COG0336	Belongs to the RNA methyltransferase TrmD family
GPY32_RS12885	COG0335	large ribosomal subunit rRNA binding
GPY32_RS12890	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GPY32_RS12895	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GPY32_RS12900	COG0237	dephospho-CoA kinase activity
GPY32_RS12910	COG1459	type II secretion system
GPY32_RS12915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY32_RS12920	COG4969	Belongs to the N-Me-Phe pilin family
GPY32_RS12925	COG0157	Belongs to the NadC ModD family
GPY32_RS12935	COG2186	Transcriptional regulator
GPY32_RS12940	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GPY32_RS12945	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY32_RS12950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY32_RS12965	COG0288	reversible hydration of carbon dioxide
GPY32_RS12970	COG0659	secondary active sulfate transmembrane transporter activity
GPY32_RS12980	COG1131	(ABC) transporter
GPY32_RS12985	COG0842	Transport permease protein
GPY32_RS12990	COG1560	Kdo2-lipid A biosynthetic process
GPY32_RS13000	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GPY32_RS13005	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GPY32_RS13010	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY32_RS13025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY32_RS13035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY32_RS13040	COG1489	DNA binding
GPY32_RS13045	COG1643	Atp-dependent helicase
GPY32_RS13050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPY32_RS13055	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPY32_RS13060	COG1049	propionate catabolic process, 2-methylcitrate cycle
GPY32_RS13065	COG3112	Uncharacterised protein family (UPF0231)
GPY32_RS13075	COG0004	ammonium transporteR
GPY32_RS13080	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY32_RS13090	COG3842	ATPase activity
GPY32_RS13095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY32_RS13110	COG2971	BadF BadG BcrA BcrD
GPY32_RS13120	COG4608	Belongs to the ABC transporter superfamily
GPY32_RS13125	COG0444	Belongs to the ABC transporter superfamily
GPY32_RS13130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY32_RS13140	COG0747	negative chemotaxis
GPY32_RS13145	COG2205	protein histidine kinase activity
GPY32_RS13145	COG2198	Histidine kinase
GPY32_RS13145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY32_RS13145	COG0784	Response regulator, receiver
GPY32_RS13150	COG2813	Specifically methylates the guanine in position
GPY32_RS13155	COG0628	permease
GPY32_RS13160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GPY32_RS13165	COG0316	Belongs to the HesB IscA family
GPY32_RS13175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY32_RS13180	COG0739	heme binding
GPY32_RS13185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPY32_RS13195	COG2027	D-alanyl-D-alanine carboxypeptidase
GPY32_RS13200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPY32_RS13205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY32_RS13210	COG1534	Rna-binding protein
GPY32_RS13215	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GPY32_RS13220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPY32_RS13225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPY32_RS13230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY32_RS13240	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY32_RS13255	COG0779	Required for maturation of 30S ribosomal subunits
GPY32_RS13260	COG0195	Participates in both transcription termination and antitermination
GPY32_RS13265	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPY32_RS13270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPY32_RS13275	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPY32_RS13280	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPY32_RS13285	COG1185	polyribonucleotide nucleotidyltransferase activity
GPY32_RS13300	COG0534	Mate efflux family protein
GPY32_RS13325	COG3153	acetyltransferase
GPY32_RS13345	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GPY32_RS13355	COG0084	hydrolase, TatD family'
GPY32_RS13360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY32_RS13365	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPY32_RS13370	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GPY32_RS13375	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPY32_RS13380	COG0813	purine-nucleoside phosphorylase activity
GPY32_RS13390	COG0560	Phosphoserine phosphatase
GPY32_RS13400	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPY32_RS13405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPY32_RS13410	COG0583	DNA-binding transcription factor activity
GPY32_RS13420	COG1022	Amp-dependent synthetase and ligase
GPY32_RS13425	COG2169	Transcriptional regulator
GPY32_RS13450	COG4964	Belongs to the GSP D family
GPY32_RS13510	COG0583	DNA-binding transcription factor activity
GPY32_RS13515	COG0531	amino acid
GPY32_RS13520	COG2731	YhcH YjgK YiaL family protein
GPY32_RS13525	COG3250	beta-galactosidase activity
GPY32_RS13530	COG1609	Transcriptional regulator
GPY32_RS13540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPY32_RS13550	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPY32_RS13555	COG2017	converts alpha-aldose to the beta-anomer
GPY32_RS13570	COG2211	Major facilitator Superfamily
GPY32_RS13575	COG1609	Transcriptional regulator
GPY32_RS13580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY32_RS13595	COG0598	Magnesium transport protein CorA
GPY32_RS13600	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPY32_RS13605	COG1349	DNA-binding transcription factor activity
GPY32_RS13610	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPY32_RS13615	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPY32_RS13630	COG2271	Major facilitator Superfamily
GPY32_RS13635	COG0584	glycerophosphoryl diester phosphodiesterase
GPY32_RS13640	COG2171	N-acyltransferase activity
GPY32_RS13645	COG3141	response to X-ray
GPY32_RS13665	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GPY32_RS13670	COG1074	ATP-dependent DNA helicase activity
GPY32_RS13675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GPY32_RS13700	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPY32_RS13700	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPY32_RS13710	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GPY32_RS13715	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GPY32_RS13720	COG2166	iron-sulfur cluster assembly
GPY32_RS13725	COG3706	GGDEF domain
GPY32_RS13730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPY32_RS13735	COG0693	protein deglycase activity
GPY32_RS13740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPY32_RS13765	COG1595	DNA-templated transcription, initiation
GPY32_RS13785	COG3056	Lipoprotein
GPY32_RS13790	COG2813	Specifically methylates the guanine in position
GPY32_RS13795	COG0271	Belongs to the BolA IbaG family
GPY32_RS13800	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY32_RS13805	COG1805	sodium ion transport
GPY32_RS13810	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY32_RS13815	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY32_RS13820	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY32_RS13825	COG2871	sodium ion transport
GPY32_RS13830	COG1477	protein flavinylation
GPY32_RS13845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPY32_RS13850	COG0514	ATP-dependent DNA helicase (RecQ)
GPY32_RS13855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY32_RS13870	COG0733	neurotransmitter:sodium symporter activity
GPY32_RS13890	COG0442	prolyl-tRNA aminoacylation
GPY32_RS13895	COG1720	tRNA m6t6A37 methyltransferase activity
GPY32_RS13900	COG0254	rRNA binding
GPY32_RS13915	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY32_RS13920	COG1671	Belongs to the UPF0178 family
GPY32_RS13945	COG3098	single-species biofilm formation
GPY32_RS13950	COG0564	pseudouridine synthase activity
GPY32_RS13960	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GPY32_RS13965	COG0024	Methionine aminopeptidase
GPY32_RS13970	COG0052	Belongs to the universal ribosomal protein uS2 family
GPY32_RS13975	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPY32_RS13980	COG0528	UMP kinase activity
GPY32_RS13985	COG0233	cytoplasmic translational termination
GPY32_RS13990	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPY32_RS13995	COG0575	Belongs to the CDS family
GPY32_RS14000	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GPY32_RS14005	COG0750	zinc metalloprotease
GPY32_RS14015	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GPY32_RS14020	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY32_RS14025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY32_RS14030	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY32_RS14035	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY32_RS14040	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPY32_RS14045	COG0587	DNA-directed DNA polymerase activity
GPY32_RS14050	COG0825	malonyl-CoA metabolic process
GPY32_RS14055	COG0037	tRNA processing
GPY32_RS14065	COG0347	Belongs to the P(II) protein family
GPY32_RS14070	COG3021	interspecies interaction between organisms
GPY32_RS14080	COG0741	lytic transglycosylase activity
GPY32_RS14080	COG1388	LysM domain
GPY32_RS14085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY32_RS14090	COG2226	methyltransferase
GPY32_RS14095	COG0328	RNA-DNA hybrid ribonuclease activity
GPY32_RS14100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPY32_RS14115	COG1960	acyl-CoA dehydrogenase activity
GPY32_RS14120	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPY32_RS14125	COG0121	glutamine amidotransferase
GPY32_RS14130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPY32_RS14135	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GPY32_RS14140	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPY32_RS14145	COG2233	PERMEase
GPY32_RS14165	COG1393	Belongs to the ArsC family
GPY32_RS14170	COG4783	chaperone-mediated protein folding
GPY32_RS14185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPY32_RS14190	COG2716	regulation of RNA biosynthetic process
GPY32_RS14195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPY32_RS14215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY32_RS14220	COG1393	Belongs to the ArsC family
GPY32_RS14250	COG2837	iron assimilation
GPY32_RS14255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY32_RS14265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY32_RS14270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY32_RS14275	COG1334	flagellar protein FlaG
GPY32_RS14280	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPY32_RS14290	COG1516	flagellar protein fliS
GPY32_RS14300	COG4191	Histidine kinase
GPY32_RS14305	COG2204	response regulator
GPY32_RS14310	COG1677	Flagellar hook-basal body complex protein FliE
GPY32_RS14320	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY32_RS14370	COG1987	bacterial-type flagellum assembly
GPY32_RS14395	COG0455	bacterial-type flagellum organization
GPY32_RS14410	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GPY32_RS14415	COG2198	Histidine kinase
GPY32_RS14415	COG0643	Histidine kinase
GPY32_RS14420	COG2201	protein-glutamate methylesterase activity
GPY32_RS14425	COG1192	Involved in chromosome partitioning
GPY32_RS14435	COG0835	chemotaxis
GPY32_RS14445	COG4133	protoheme IX ABC transporter activity
GPY32_RS14450	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY32_RS14455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY32_RS14460	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY32_RS14465	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GPY32_RS14470	COG1138	Cytochrome C-type biogenesis protein
GPY32_RS14475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY32_RS14490	COG2853	Lipoprotein
GPY32_RS14495	COG2067	long-chain fatty acid transport protein
GPY32_RS14500	COG2067	long-chain fatty acid transport protein
GPY32_RS14515	COG0183	Belongs to the thiolase family
GPY32_RS14520	COG1024	Enoyl-CoA hydratase
GPY32_RS14520	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPY32_RS14535	COG2062	phosphohistidine phosphatase, SixA
GPY32_RS14540	COG2840	Smr protein MutS2
GPY32_RS14545	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY32_RS14550	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPY32_RS14555	COG2860	membrane
GPY32_RS14565	COG3101	peptidyl-lysine hydroxylation
GPY32_RS14580	COG0431	NADPH-dependent FMN reductase
GPY32_RS14585	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GPY32_RS14585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY32_RS14590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPY32_RS14595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY32_RS14600	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPY32_RS14610	COG0101	tRNA pseudouridine synthase activity
GPY32_RS14615	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPY32_RS14620	COG0285	dihydrofolate synthase activity
GPY32_RS14625	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GPY32_RS14630	COG1286	toxin biosynthetic process
GPY32_RS14635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPY32_RS14640	COG0583	DNA-binding transcription factor activity
GPY32_RS14645	COG0745	RESPONSE REGULATOR receiver
GPY32_RS14655	COG2832	Protein of unknown function (DUF454)
GPY32_RS14660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPY32_RS14670	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPY32_RS14675	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPY32_RS14680	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPY32_RS14685	COG0814	amino acid
GPY32_RS14690	COG0251	oxidation-reduction process
GPY32_RS14695	COG3681	Belongs to the UPF0597 family
GPY32_RS14710	COG2261	transglycosylase associated protein
GPY32_RS14715	COG2983	Belongs to the UPF0260 family
GPY32_RS14720	COG0668	transmembrane transport
GPY32_RS14725	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GPY32_RS14730	COG0346	lactoylglutathione lyase activity
GPY32_RS14740	COG1785	Belongs to the alkaline phosphatase family
GPY32_RS14760	COG2226	methyltransferase
GPY32_RS14775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY32_RS14780	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY32_RS14790	COG3139	Protein of unknown function (DUF1315)
GPY32_RS14795	COG0252	asparaginase activity
GPY32_RS14800	COG0616	signal peptide processing
GPY32_RS14805	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPY32_RS14805	COG1902	pentaerythritol trinitrate reductase activity
GPY32_RS14810	COG0778	Nitroreductase
GPY32_RS14815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY32_RS14835	COG0123	including yeast histone deacetylase and acetoin utilization protein
GPY32_RS14845	COG3083	sulfuric ester hydrolase activity
GPY32_RS14850	COG3082	Protein of unknown function (DUF1414)
GPY32_RS14855	COG3081	Nucleoid-associated protein
GPY32_RS14870	COG1757	Na H antiporter
GPY32_RS14875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPY32_RS14880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY32_RS14885	COG2095	MarC family integral membrane protein
GPY32_RS14890	COG1454	alcohol dehydrogenase
GPY32_RS14890	COG1012	belongs to the aldehyde dehydrogenase family
GPY32_RS14910	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GPY32_RS14920	COG2056	Na+-H+ antiporter family
GPY32_RS14925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPY32_RS14940	COG2885	chlorophyll binding
GPY32_RS14950	COG0346	lactoylglutathione lyase activity
GPY32_RS14955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPY32_RS14960	COG4660	Part of a membrane complex involved in electron transport
GPY32_RS14965	COG4659	FMN binding
GPY32_RS14970	COG4658	electron transport chain
GPY32_RS14975	COG4656	Part of a membrane complex involved in electron transport
GPY32_RS14980	COG2878	Part of a membrane complex involved in electron transport
GPY32_RS14985	COG4657	Part of a membrane complex involved in electron transport
GPY32_RS15000	COG0556	nucleotide-excision repair
GPY32_RS15005	COG2204	response regulator
GPY32_RS15010	COG2198	Histidine kinase
GPY32_RS15015	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GPY32_RS15020	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPY32_RS15025	COG0521	Mo-molybdopterin cofactor biosynthetic process
GPY32_RS15030	COG0315	cyclic pyranopterin monophosphate synthase activity
GPY32_RS15035	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPY32_RS15040	COG0314	molybdopterin synthase activity
GPY32_RS15050	COG0601	transmembrane transport
GPY32_RS15055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY32_RS15060	COG0444	Belongs to the ABC transporter superfamily
GPY32_RS15070	COG0435	Glutathione S-transferase
GPY32_RS15080	COG3174	membrane
GPY32_RS15085	COG0280	phosphate acetyltransferase
GPY32_RS15085	COG0857	belongs to the CobB CobQ family
GPY32_RS15090	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPY32_RS15095	COG3092	negative regulation of chromosome organization
GPY32_RS15105	COG4120	Belongs to the binding-protein-dependent transport system permease family
GPY32_RS15110	COG1122	ATPase activity
GPY32_RS15115	COG0366	Alpha amylase catalytic
GPY32_RS15120	COG3706	GGDEF domain
GPY32_RS15120	COG0745	RESPONSE REGULATOR receiver
GPY32_RS15125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY32_RS15130	COG0653	protein targeting
GPY32_RS15135	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GPY32_RS15140	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPY32_RS15145	COG2186	Transcriptional regulator
GPY32_RS15155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY32_RS15155	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY32_RS15160	COG0489	protein tyrosine kinase activity
GPY32_RS15165	COG0572	uridine kinase
GPY32_RS15175	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GPY32_RS15180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPY32_RS15185	COG0659	secondary active sulfate transmembrane transporter activity
GPY32_RS15190	COG1530	ribonuclease E activity
GPY32_RS15195	COG0564	pseudouridine synthase activity
GPY32_RS15200	COG0424	maF-like protein
GPY32_RS15205	COG1399	metal-binding, possibly nucleic acid-binding protein
GPY32_RS15215	COG0416	fatty acid biosynthetic process
GPY32_RS15220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY32_RS15250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPY32_RS15255	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPY32_RS15265	COG0084	hydrolase, TatD family'
GPY32_RS15270	COG1263	PTS System
GPY32_RS15270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY32_RS15290	COG0733	neurotransmitter:sodium symporter activity
GPY32_RS15305	COG4667	esterase of the alpha-beta hydrolase superfamily
GPY32_RS15310	COG0469	pyruvate kinase activity
GPY32_RS15315	COG1940	carbohydrate kinase activity
GPY32_RS15320	COG0784	Response regulator, receiver
GPY32_RS15320	COG0835	chemotaxis
GPY32_RS15325	COG0587	DNA-directed DNA polymerase activity
GPY32_RS15340	COG1028	Short-chain dehydrogenase reductase Sdr
GPY32_RS15345	COG0616	signal peptide processing
GPY32_RS15350	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GPY32_RS15355	COG0539	negative regulation of cytoplasmic translation
GPY32_RS15365	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GPY32_RS15370	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GPY32_RS15375	COG0284	orotidine-5'-phosphate decarboxylase activity
GPY32_RS15380	COG4166	transmembrane transport
GPY32_RS15395	COG0463	Glycosyl transferase, family 2
GPY32_RS15405	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GPY32_RS15415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPY32_RS15415	COG3008	intermembrane lipid transfer
GPY32_RS15420	COG2995	paraquat-inducible protein a
GPY32_RS15425	COG3258	Cytochrome c
GPY32_RS15430	COG2863	cytochrome
GPY32_RS15470	COG4232	protein-disulfide reductase activity
GPY32_RS15475	COG3118	belongs to the thioredoxin family
GPY32_RS15505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY32_RS15515	COG0577	efflux transmembrane transporter activity
GPY32_RS15515	COG1136	(ABC) transporter
GPY32_RS15520	COG1136	(ABC) transporter
GPY32_RS15520	COG0577	efflux transmembrane transporter activity
GPY32_RS15525	COG0577	efflux transmembrane transporter activity
GPY32_RS15525	COG1136	(ABC) transporter
GPY32_RS15530	COG1335	isochorismatase
GPY32_RS15580	COG5002	protein histidine kinase activity
GPY32_RS15580	COG3850	Histidine kinase
GPY32_RS15585	COG0745	RESPONSE REGULATOR receiver
GPY32_RS15595	COG0840	transmembrane signaling receptor activity
GPY32_RS15600	COG1032	radical SAM domain protein
GPY32_RS15605	COG2203	Gaf domain
GPY32_RS15605	COG5001	Diguanylate cyclase
GPY32_RS15605	COG3706	GGDEF domain
GPY32_RS15605	COG4251	negative regulation of phosphorylation
GPY32_RS15620	COG0583	DNA-binding transcription factor activity
GPY32_RS15630	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPY32_RS15640	COG2350	Protein conserved in bacteria
GPY32_RS15645	COG1607	acyl-coa hydrolase
GPY32_RS15650	COG2917	probably involved in intracellular septation
GPY32_RS15670	COG1301	dicarboxylic acid transport
GPY32_RS15680	COG0318	PFAM AMP-dependent synthetase and ligase
GPY32_RS15685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY32_RS15690	COG0159	tryptophan synthase activity
GPY32_RS15695	COG0133	tryptophan synthase activity
GPY32_RS15700	COG0134	indole-3-glycerol-phosphate synthase activity
GPY32_RS15700	COG0135	phosphoribosylanthranilate isomerase activity
GPY32_RS15705	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPY32_RS15710	COG0512	Glutamine amidotransferase of anthranilate synthase
GPY32_RS15715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY32_RS15725	COG0613	PHP domain protein
GPY32_RS15730	COG0009	L-threonylcarbamoyladenylate synthase
GPY32_RS15740	COG1187	pseudouridine synthase activity
GPY32_RS15750	COG3099	Belongs to the UPF0263 family
GPY32_RS15755	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPY32_RS15765	COG0417	DNA replication proofreading
GPY32_RS15770	COG2197	response regulator
GPY32_RS15775	COG0322	excinuclease ABC activity
GPY32_RS15815	COG0019	diaminopimelate decarboxylase activity
GPY32_RS15840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY32_RS15845	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY32_RS15850	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY32_RS15870	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GPY32_RS15880	COG0437	4 iron, 4 sulfur cluster binding
GPY32_RS15885	COG3301	Polysulphide reductase, NrfD
GPY32_RS15890	COG1138	Cytochrome C-type biogenesis protein
GPY32_RS15900	COG4235	cytochrome complex assembly
GPY32_RS15900	COG3088	subunit of a heme lyase
GPY32_RS15910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY32_RS15935	COG2989	Protein conserved in bacteria
GPY32_RS15940	COG3108	Peptidase M15
GPY32_RS15945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY32_RS15960	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPY32_RS15985	COG1846	Transcriptional regulator
GPY32_RS15990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY32_RS15995	COG0840	transmembrane signaling receptor activity
GPY32_RS16015	COG1448	Aminotransferase
GPY32_RS16040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY32_RS16050	COG0017	Asparaginyl-tRNA synthetase
GPY32_RS16060	COG0720	synthase
GPY32_RS16070	COG2200	EAL domain
GPY32_RS16075	COG1760	l-serine dehydratase
GPY32_RS16080	COG0814	amino acid
GPY32_RS16085	COG0494	nUDIX hydrolase
GPY32_RS16095	COG0784	Response regulator, receiver
GPY32_RS16095	COG2205	protein histidine kinase activity
GPY32_RS16100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY32_RS16120	COG3106	COG3106 Predicted ATPase
GPY32_RS16125	COG3768	UPF0283 membrane protein
GPY32_RS16135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY32_RS16275	COG0346	lactoylglutathione lyase activity
GPY32_RS16365	COG2026	Addiction module toxin, RelE StbE family
GPY32_RS16405	COG1051	belongs to the nudix hydrolase family
GPY32_RS16625	COG0456	acetyltransferase
GPY32_RS16640	COG0346	lactoylglutathione lyase activity
GPY32_RS16810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GPY32_RS16810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPY32_RS17010	COG1757	Na H antiporter
GPY32_RS17015	COG0174	glutamine synthetase
GPY32_RS17025	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GPY32_RS17030	COG1917	Cupin 2, conserved barrel domain protein
GPY32_RS17030	COG1396	sequence-specific DNA binding
GPY32_RS17035	COG1012	belongs to the aldehyde dehydrogenase family
GPY32_RS17040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY32_RS17050	COG2957	Belongs to the agmatine deiminase family
GPY32_RS17055	COG1012	belongs to the aldehyde dehydrogenase family
GPY32_RS17060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPY32_RS17065	COG1227	inorganic diphosphatase activity
GPY32_RS17075	COG2200	EAL domain
GPY32_RS17075	COG2771	luxR family
GPY32_RS17085	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPY32_RS17100	COG1846	Transcriptional regulator
GPY32_RS17105	COG2315	Protein conserved in bacteria
GPY32_RS17125	COG0110	maltose O-acetyltransferase activity
GPY32_RS17155	COG3063	Type IV pilus biogenesis stability protein PilW
GPY32_RS17160	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GPY32_RS17175	COG0531	amino acid
GPY32_RS17185	COG1560	Kdo2-lipid A biosynthetic process
GPY32_RS17190	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GPY32_RS17195	COG1280	lysine exporter protein (LysE YggA)
GPY32_RS17205	COG1115	amino acid carrier protein
GPY32_RS17230	COG1368	sulfuric ester hydrolase activity
GPY32_RS17235	COG0642	Histidine kinase
GPY32_RS17240	COG0745	RESPONSE REGULATOR receiver
GPY32_RS17250	COG1028	Short-chain dehydrogenase reductase Sdr
GPY32_RS17260	COG1022	Amp-dependent synthetase and ligase
GPY32_RS17270	COG2113	Glycine betaine
GPY32_RS17275	COG4176	ABC-type proline glycine betaine transport system permease component
GPY32_RS17295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY32_RS17300	COG0456	acetyltransferase
GPY32_RS17305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPY32_RS17310	COG0662	Cupin 2, conserved barrel domain protein
GPY32_RS17315	COG0527	aspartate kinase activity
GPY32_RS17320	COG1858	cytochrome C peroxidase
GPY32_RS17335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY32_RS17350	COG3290	protein histidine kinase activity
GPY32_RS17355	COG4565	transcriptional regulatory protein
GPY32_RS17360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPY32_RS17365	COG0363	glucosamine-6-phosphate deaminase activity
GPY32_RS17370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPY32_RS17390	COG3284	Transcriptional regulator
GPY32_RS17395	COG1012	belongs to the aldehyde dehydrogenase family
GPY32_RS17465	COG4669	(LipO)protein
GPY32_RS17485	COG3177	Filamentation induced by cAMP protein fic
GPY32_RS17535	COG4792	protein secretion
GPY32_RS17540	COG4791	protein targeting
GPY32_RS17545	COG4794	Type iii secretion
GPY32_RS17550	COG4790	Type iii secretion
GPY32_RS17555	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY32_RS17620	COG0457	Tetratricopeptide repeat
GPY32_RS17640	COG0730	response to heat
GPY32_RS17670	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPY32_RS17675	COG0372	Belongs to the citrate synthase family
GPY32_RS17685	COG2828	Protein conserved in bacteria
GPY32_RS17695	COG0456	acetyltransferase
GPY32_RS17710	COG0561	phosphatase activity
GPY32_RS17715	COG0602	queuosine metabolic process
GPY32_RS17720	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPY32_RS17725	COG3706	GGDEF domain
GPY32_RS17765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY32_RS17770	COG0840	transmembrane signaling receptor activity
GPY32_RS17775	COG1254	Belongs to the acylphosphatase family
GPY32_RS17780	COG2920	part of a sulfur-relay system
GPY32_RS17790	COG0670	Belongs to the BI1 family
GPY32_RS17795	COG1126	abc transporter atp-binding protein
GPY32_RS17800	COG0765	amino acid transport
GPY32_RS17805	COG4597	amino acid ABC transporter
GPY32_RS17810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY32_RS17825	COG1666	GTP binding
GPY32_RS17830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY32_RS17850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPY32_RS17850	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GPY32_RS17855	COG3008	intermembrane lipid transfer
GPY32_RS17860	COG2995	paraquat-inducible protein a
GPY32_RS17865	COG1132	(ABC) transporter
GPY32_RS17870	COG1956	GAF domain-containing protein
GPY32_RS17875	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GPY32_RS17890	COG0308	aminopeptidase N
GPY32_RS17900	COG2902	Dehydrogenase
GPY32_RS17905	COG0167	dihydroorotate dehydrogenase activity
GPY32_RS17920	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY32_RS17920	COG0116	Belongs to the methyltransferase superfamily
GPY32_RS17945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY32_RS17950	COG1067	ATP-dependent peptidase activity
GPY32_RS17955	COG3120	sequence-specific DNA binding
GPY32_RS17990	COG3278	Belongs to the heme-copper respiratory oxidase family
GPY32_RS18005	COG2010	Cytochrome c
GPY32_RS18015	COG2217	Heavy metal translocating P-type atpase
GPY32_RS18030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY32_RS18035	COG0589	response to stress
GPY32_RS18045	COG0037	tRNA processing
GPY32_RS18065	COG3842	ATPase activity
GPY32_RS18070	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPY32_RS18075	COG1177	transmembrane transport
GPY32_RS18080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY32_RS18085	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY32_RS18090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GPY32_RS18100	COG0004	ammonium transporteR
GPY32_RS18140	COG0437	4 iron, 4 sulfur cluster binding
GPY32_RS18145	COG3383	formate dehydrogenase (NAD+) activity
GPY32_RS18145	COG0243	molybdopterin cofactor binding
GPY32_RS18155	COG3381	protein complex oligomerization
GPY32_RS18180	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPY32_RS18185	COG0488	(ABC) transporter
GPY32_RS18195	COG4191	Histidine kinase
GPY32_RS18200	COG2204	response regulator
GPY32_RS18220	COG3842	ATPase activity
GPY32_RS18225	COG0746	molybdenum cofactor guanylyltransferase activity
GPY32_RS18230	COG0303	'Molybdopterin
GPY32_RS18240	COG1940	carbohydrate kinase activity
GPY32_RS18280	COG3290	protein histidine kinase activity
GPY32_RS18280	COG0840	transmembrane signaling receptor activity
GPY32_RS18285	COG0791	NLP P60 protein
GPY32_RS18295	COG3706	GGDEF domain
GPY32_RS18300	COG2201	protein-glutamate methylesterase activity
GPY32_RS18315	COG0307	riboflavin synthase, alpha
GPY32_RS18320	COG0534	Mate efflux family protein
GPY32_RS18330	COG1793	dna ligase
GPY32_RS18365	COG2204	response regulator
GPY32_RS18375	COG0438	transferase activity, transferring glycosyl groups
GPY32_RS18410	COG0438	transferase activity, transferring glycosyl groups
GPY32_RS18415	COG1215	transferase activity, transferring glycosyl groups
GPY32_RS18420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPY32_RS18430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY32_RS18445	COG1643	Atp-dependent helicase
GPY32_RS18450	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPY32_RS18465	COG3302	dmso reductase anchor subunit
GPY32_RS18470	COG0437	4 iron, 4 sulfur cluster binding
GPY32_RS18475	COG0243	molybdopterin cofactor binding
GPY32_RS18515	COG0443	Heat shock 70 kDa protein
GPY32_RS18520	COG0443	Heat shock 70 kDa protein
GPY32_RS18550	COG1132	(ABC) transporter
GPY32_RS18555	COG1132	(ABC) transporter
GPY32_RS18580	COG0814	amino acid
GPY32_RS18595	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPY32_RS18665	COG1522	sequence-specific DNA binding
GPY32_RS18700	COG0515	serine threonine protein kinase
GPY32_RS18725	COG3501	Rhs element vgr protein
GPY32_RS18745	COG2885	chlorophyll binding
GPY32_RS18765	COG0739	heme binding
GPY32_RS18775	COG0861	Integral membrane protein TerC family
GPY32_RS18785	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY32_RS18790	COG1328	CTP reductase activity
GPY32_RS18795	COG1280	lysine exporter protein (LysE YggA)
GPY32_RS18805	COG3300	MHYT domain
GPY32_RS18805	COG5001	Diguanylate cyclase
GPY32_RS18815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY32_RS18815	COG4191	Histidine kinase
GPY32_RS18820	COG0471	metal ion transport
GPY32_RS18855	COG0583	DNA-binding transcription factor activity
GPY32_RS18860	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GPY32_RS19090	COG1783	phage Terminase large subunit
GPY32_RS19135	COG0557	exoribonuclease II activity
GPY32_RS19140	COG1278	Cold shock
GPY32_RS19250	COG0625	glutathione transferase activity
GPY32_RS19260	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GPY32_RS19270	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY32_RS19280	COG0601	transmembrane transport
GPY32_RS19285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY32_RS19290	COG0444	Belongs to the ABC transporter superfamily
GPY32_RS19310	COG3291	Pkd domain containing protein
GPY32_RS19320	COG1177	transmembrane transport
GPY32_RS19325	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPY32_RS19335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPY32_RS19340	COG2423	ornithine cyclodeaminase activity
GPY32_RS19360	COG3938	Belongs to the proline racemase family
GPY32_RS19390	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GPY32_RS19395	COG1451	nucleotide metabolic process
GPY32_RS19400	COG3475	LICD family
GPY32_RS19405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY32_RS19410	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPY32_RS19430	COG0583	DNA-binding transcription factor activity
GPY32_RS19450	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GPY32_RS19455	COG4139	cobalamin transport
GPY32_RS19460	COG2988	succinylglutamate desuccinylase activity
GPY32_RS19485	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GPY32_RS19490	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GPY32_RS19495	COG0702	epimerase
GPY32_RS19505	COG2925	Exonuclease
GPY32_RS19510	COG1380	Effector of murein hydrolase LrgA
GPY32_RS19515	COG1346	cytolysis
GPY32_RS19520	COG0295	cytidine deaminase activity
GPY32_RS19525	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GPY32_RS19530	COG0500	methyltransferase
GPY32_RS19540	COG0776	regulation of translation
GPY32_RS19555	COG0072	phenylalanine-tRNA ligase activity
GPY32_RS19555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY32_RS19560	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPY32_RS19565	COG3706	GGDEF domain
GPY32_RS19595	COG0393	Putative heavy-metal-binding
GPY32_RS19605	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GPY32_RS19615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPY32_RS19630	COG2188	Transcriptional regulator
GPY32_RS19635	COG1228	amidohydrolase
GPY32_RS19640	COG0010	Belongs to the arginase family
GPY32_RS19645	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GPY32_RS19650	COG2986	histidine ammonia-lyase
GPY32_RS19665	COG0277	FAD linked oxidase domain protein
GPY32_RS19665	COG0247	lactate metabolic process
GPY32_RS19700	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GPY32_RS19715	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GPY32_RS19720	COG1643	Atp-dependent helicase
GPY32_RS19725	COG0281	malic enzyme
GPY32_RS19730	COG2949	membrane
GPY32_RS19735	COG0471	metal ion transport
GPY32_RS19740	COG0745	RESPONSE REGULATOR receiver
GPY32_RS19740	COG3706	GGDEF domain
GPY32_RS19760	COG0492	ferredoxin-NADP+ reductase activity
GPY32_RS19765	COG4988	ABC transporter
GPY32_RS19770	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GPY32_RS19775	COG3048	D-serine ammonia-lyase activity
GPY32_RS19780	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPY32_RS19790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY32_RS19790	COG4191	Histidine kinase
GPY32_RS19805	COG3070	regulator of competence-specific genes
GPY32_RS19820	COG2431	L-lysine efflux transmembrane transporter activity
GPY32_RS19830	COG0076	glutamate decarboxylase activity
GPY32_RS19835	COG1737	Transcriptional regulator
GPY32_RS19850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY32_RS19855	COG2985	domain, Protein
GPY32_RS19855	COG3273	potassium ion transport
GPY32_RS19860	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPY32_RS19875	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPY32_RS19890	COG4181	ATPase activity
GPY32_RS19895	COG0534	Mate efflux family protein
GPY32_RS19900	COG0702	epimerase
GPY32_RS19905	COG3005	denitrification pathway
GPY32_RS19935	COG2814	Major facilitator Superfamily
GPY32_RS19940	COG1187	pseudouridine synthase activity
GPY32_RS19945	COG1061	Type III restriction enzyme res subunit
GPY32_RS19955	COG0745	RESPONSE REGULATOR receiver
GPY32_RS19960	COG2205	protein histidine kinase activity
GPY32_RS19965	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GPY32_RS19995	COG3313	Fe-S protein
GPY32_RS20020	COG0493	'glutamate synthase
GPY32_RS20030	COG0398	Pfam SNARE associated Golgi protein
GPY32_RS20035	COG4134	Bacterial extracellular solute-binding protein
GPY32_RS20040	COG4135	transport system, permease component
GPY32_RS20045	COG4136	ATPase activity
GPY32_RS20050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPY32_RS20065	COG3604	Transcriptional regulator
GPY32_RS20070	COG1151	hydroxylamine reductase activity
GPY32_RS20075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY32_RS20085	COG0564	pseudouridine synthase activity
GPY32_RS20095	COG0733	neurotransmitter:sodium symporter activity
GPY32_RS20105	COG0626	cystathionine gamma-synthase activity
GPY32_RS20110	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPY32_RS20115	COG5380	lipid catabolic process
GPY32_RS20120	COG2818	Glycosylase
GPY32_RS20135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY32_RS20140	COG1983	PspC domain protein
GPY32_RS20150	COG1842	Phage shock protein A
GPY32_RS20155	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GPY32_RS20165	COG4168	peptide transport system, permease
GPY32_RS20170	COG4171	peptide transport system, permease
GPY32_RS20180	COG4172	Belongs to the ABC transporter superfamily
GPY32_RS20190	COG1227	inorganic diphosphatase activity
GPY32_RS20205	COG0243	molybdopterin cofactor binding
GPY32_RS20210	COG3005	denitrification pathway
GPY32_RS20215	COG4459	periplasmic nitrate reductase
GPY32_RS20220	COG0390	transport system, permease component
GPY32_RS20230	COG2116	formate transmembrane transporter activity
GPY32_RS20255	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPY32_RS20260	COG1435	thymidine kinase activity
GPY32_RS20265	COG0215	cysteine-tRNA ligase activity
GPY32_RS20270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPY32_RS20275	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY32_RS20280	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY32_RS20290	COG3012	SEC-C Motif Domain Protein
GPY32_RS20295	COG0140	phosphoribosyl-ATP diphosphatase activity
GPY32_RS20295	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GPY32_RS20300	COG0107	imidazoleglycerol-phosphate synthase activity
GPY32_RS20305	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPY32_RS20310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPY32_RS20315	COG0131	Imidazoleglycerol-phosphate dehydratase
GPY32_RS20315	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPY32_RS20320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPY32_RS20325	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPY32_RS20330	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GPY32_RS20345	COG1757	Na H antiporter
GPY32_RS20355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY32_RS20365	COG0482	sulfurtransferase activity
GPY32_RS20370	COG2915	High frequency lysogenization protein hflD homolog
GPY32_RS20375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPY32_RS20400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GPY32_RS20415	COG0300	oxidoreductase activity
GPY32_RS20425	COG0501	Belongs to the peptidase M48B family
GPY32_RS20435	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GPY32_RS20445	COG0156	8-amino-7-oxononanoate synthase activity
GPY32_RS20450	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPY32_RS20455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GPY32_RS20460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY32_RS20470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPY32_RS20475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GPY32_RS20480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GPY32_RS20485	COG1674	ftsk spoiiie
GPY32_RS20495	COG0686	Belongs to the AlaDH PNT family
GPY32_RS20505	COG0583	DNA-binding transcription factor activity
GPY32_RS20520	COG3568	Endonuclease Exonuclease Phosphatase
GPY32_RS20550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY32_RS20555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY32_RS20570	COG0840	transmembrane signaling receptor activity
GPY32_RS20585	COG0784	Response regulator, receiver
GPY32_RS20585	COG5002	protein histidine kinase activity
GPY32_RS20595	COG0754	glutathionylspermidine amidase activity
GPY32_RS20605	COG3766	membrane
GPY32_RS20615	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GPY32_RS20620	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GPY32_RS20625	COG2885	chlorophyll binding
GPY32_RS20630	COG0823	Involved in the tonB-independent uptake of proteins
GPY32_RS20645	COG0811	peptide transport
GPY32_RS20650	COG0824	Thioesterase
GPY32_RS20660	COG4890	Cyd operon protein YbgT
GPY32_RS20665	COG1294	oxidase, subunit
GPY32_RS20670	COG1271	oxidase subunit
GPY32_RS20675	COG2255	four-way junction helicase activity
GPY32_RS20680	COG0632	four-way junction helicase activity
GPY32_RS20685	COG0840	transmembrane signaling receptor activity
GPY32_RS20690	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GPY32_RS20695	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GPY32_RS20700	COG1801	Protein of unknown function DUF72
GPY32_RS20705	COG4106	trans-aconitate 2-methyltransferase activity
GPY32_RS20710	COG0500	methyltransferase
GPY32_RS20720	COG4067	protein conserved in archaea
GPY32_RS20720	COG0189	ligase activity
GPY32_RS20740	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GPY32_RS20745	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GPY32_RS20750	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GPY32_RS20755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY32_RS20760	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPY32_RS20765	COG0745	RESPONSE REGULATOR receiver
GPY32_RS20770	COG3381	protein complex oligomerization
GPY32_RS20775	COG1609	Transcriptional regulator
GPY32_RS20780	COG3070	regulator of competence-specific genes
GPY32_RS20800	COG0297	glycogen (starch) synthase activity
GPY32_RS20805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPY32_RS20810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY32_RS20820	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GPY32_RS20830	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GPY32_RS20835	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GPY32_RS20840	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPY32_RS20850	COG0542	response to heat
GPY32_RS20855	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GPY32_RS20860	COG1278	Cold shock
GPY32_RS20870	COG1187	pseudouridine synthase activity
GPY32_RS20875	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPY32_RS20885	COG1199	ATP-dependent helicase activity
GPY32_RS20890	COG0730	response to heat
GPY32_RS20895	COG3923	Primosomal replication protein n
GPY32_RS20905	COG0708	Exodeoxyribonuclease III
GPY32_RS20920	COG4215	(ABC) transporter
GPY32_RS20950	COG1882	Formate acetyltransferase
GPY32_RS20960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY32_RS20970	COG3013	Belongs to the UPF0304 family
GPY32_RS20980	COG2766	serine protein kinase
GPY32_RS20985	COG2718	Belongs to the UPF0229 family
GPY32_RS20990	COG2719	SpoVR family
GPY32_RS20995	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GPY32_RS21005	COG1663	tetraacyldisaccharide 4'-kinase activity
GPY32_RS21010	COG1132	(ABC) transporter
GPY32_RS21015	COG0658	competence protein
GPY32_RS21015	COG2333	competence protein COMEC
GPY32_RS21025	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPY32_RS21030	COG1136	(ABC) transporter
GPY32_RS21035	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPY32_RS21045	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPY32_RS21060	COG1252	NADH dehydrogenase
GPY32_RS21070	COG3150	esterase
GPY32_RS21095	COG0537	adenosine 5'-monophosphoramidase activity
GPY32_RS21125	COG0517	IMP dehydrogenase activity
GPY32_RS21125	COG0516	GMP reductase activity
GPY32_RS21135	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GPY32_RS21140	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GPY32_RS21145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY32_RS21155	COG2199	diguanylate cyclase activity
GPY32_RS21170	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GPY32_RS21175	COG1946	Acyl-CoA thioesterase
GPY32_RS21185	COG1522	sequence-specific DNA binding
GPY32_RS21215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY32_RS21220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY32_RS21265	COG0477	Major facilitator Superfamily
GPY32_RS21270	COG2855	membrane
GPY32_RS21290	COG1441	menaquinone biosynthetic process
GPY32_RS21295	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPY32_RS21300	COG0596	Alpha beta hydrolase
GPY32_RS21305	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GPY32_RS21310	COG1169	isochorismate synthase
GPY32_RS21315	COG0436	Aminotransferase
GPY32_RS21320	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GPY32_RS21325	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GPY32_RS21340	COG1555	photosystem II stabilization
GPY32_RS21345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY32_RS21350	COG0776	regulation of translation
GPY32_RS21355	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPY32_RS21360	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPY32_RS21370	COG0544	peptidyl-prolyl cis-trans isomerase activity
GPY32_RS21380	COG2204	response regulator
GPY32_RS21390	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GPY32_RS21395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GPY32_RS21400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPY32_RS21405	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GPY32_RS21425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY32_RS21430	COG0569	domain protein
GPY32_RS21435	COG0513	Belongs to the DEAD box helicase family
GPY32_RS21440	COG1253	flavin adenine dinucleotide binding
GPY32_RS21470	COG0318	PFAM AMP-dependent synthetase and ligase
GPY32_RS21470	COG0204	Acyl-transferase
GPY32_RS21475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY32_RS21480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY32_RS21495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY32_RS21500	COG1216	Glycosyl transferase, family 2
GPY32_RS21505	COG2986	histidine ammonia-lyase
GPY32_RS21530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPY32_RS21535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY32_RS21540	COG1028	Short-chain dehydrogenase reductase Sdr
GPY32_RS21545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPY32_RS21560	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPY32_RS21565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY32_RS21570	COG0583	DNA-binding transcription factor activity
GPY32_RS21575	COG2951	lytic endotransglycosylase activity
GPY32_RS21580	COG3100	YcgL domain-containing protein
GPY32_RS21585	COG0850	regulation of cytokinetic process
GPY32_RS21590	COG2894	cell division
GPY32_RS21595	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GPY32_RS21600	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GPY32_RS21605	COG0318	PFAM AMP-dependent synthetase and ligase
GPY32_RS21610	COG2267	carboxylic ester hydrolase activity
GPY32_RS21625	COG1214	PFAM Peptidase M22, glycoprotease
GPY32_RS21630	COG1199	ATP-dependent helicase activity
GPY32_RS21635	COG0788	formyltetrahydrofolate deformylase activity
GPY32_RS21640	COG3102	Protein conserved in bacteria
GPY32_RS21650	COG0018	arginyl-trna synthetase
GPY32_RS21670	COG1918	ferrous iron import across plasma membrane
GPY32_RS21685	COG4977	sequence-specific DNA binding
GPY32_RS21690	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GPY32_RS21695	COG1121	(ABC) transporter
GPY32_RS21700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPY32_RS21710	COG0045	succinate-CoA ligase (ADP-forming) activity
GPY32_RS21715	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY32_RS21720	COG0567	Dehydrogenase, E1 component
GPY32_RS21725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPY32_RS21730	COG1053	succinate dehydrogenase
GPY32_RS21735	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GPY32_RS21740	COG2009	succinate dehydrogenase
GPY32_RS21750	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPY32_RS21760	COG0033	Phosphoglucomutase
GPY32_RS21765	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GPY32_RS21770	COG0596	Alpha beta hydrolase
GPY32_RS21780	COG0716	FMN binding
GPY32_RS21790	COG0735	belongs to the Fur family
GPY32_RS21795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY32_RS21800	COG2190	(PTS) system
GPY32_RS21800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY32_RS21800	COG1263	PTS System
GPY32_RS21810	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPY32_RS21815	COG1940	carbohydrate kinase activity
GPY32_RS21815	COG1846	Transcriptional regulator
GPY32_RS21820	COG4651	solute:proton antiporter activity
GPY32_RS21820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPY32_RS21825	COG0367	asparagine synthase
GPY32_RS21830	COG0250	Participates in transcription elongation, termination and antitermination
GPY32_RS21835	COG3104	oligopeptide transport
GPY32_RS21840	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GPY32_RS21845	COG0563	adenylate kinase activity
GPY32_RS21850	COG0326	Molecular chaperone. Has ATPase activity
GPY32_RS21855	COG3710	Transcriptional regulator
GPY32_RS21875	COG0622	Phosphoesterase
GPY32_RS21905	COG1090	epimerase
GPY32_RS21910	COG0300	oxidoreductase activity
GPY32_RS21920	COG3118	belongs to the thioredoxin family
GPY32_RS21925	COG0330	HflC and HflK could
GPY32_RS21950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPY32_RS21955	COG3115	cell septum assembly
GPY32_RS21960	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GPY32_RS21965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPY32_RS21975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY32_RS21980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPY32_RS21985	COG2190	(PTS) system
GPY32_RS21995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY32_RS22000	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY32_RS22010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY32_RS22020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY32_RS22030	COG3951	Flagellar rod assembly protein muramidase FlgJ
GPY32_RS22030	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPY32_RS22035	COG1706	bacterial-type flagellum-dependent cell motility
GPY32_RS22040	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GPY32_RS22045	COG4786	Flagellar basal body rod
GPY32_RS22050	COG4787	bacterial-type flagellum-dependent cell motility
GPY32_RS22060	COG1749	Flagellar hook protein flgE
GPY32_RS22065	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPY32_RS22070	COG1558	bacterial-type flagellum-dependent cell motility
GPY32_RS22075	COG1815	bacterial-type flagellum-dependent cell motility
GPY32_RS22080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPY32_RS22085	COG0835	chemotaxis
GPY32_RS22085	COG0784	Response regulator, receiver
GPY32_RS22145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY32_RS22150	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPY32_RS22165	COG2217	Heavy metal translocating P-type atpase
GPY32_RS22165	COG2608	mercury ion transmembrane transporter activity
GPY32_RS22205	COG2840	Smr protein MutS2
GPY32_RS22210	COG1187	pseudouridine synthase activity
GPY32_RS22220	COG0737	Belongs to the 5'-nucleotidase family
GPY32_RS22225	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GPY32_RS22230	COG2912	Transglutaminase-like superfamily
GPY32_RS22235	COG3094	Invasion gene expression up-regulator, SirB
GPY32_RS22240	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY32_RS22245	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPY32_RS22250	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPY32_RS22265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPY32_RS22270	COG0193	aminoacyl-tRNA hydrolase activity
GPY32_RS22275	COG0012	GTP binding
GPY32_RS22390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY32_RS22400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPY32_RS22405	COG1702	phosphate starvation-inducible protein PhoH
GPY32_RS22410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPY32_RS22415	COG4535	Mg2 and Co2 transporter CorC
GPY32_RS22420	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GPY32_RS22425	COG2888	peptidyl-tyrosine sulfation
GPY32_RS22430	COG0495	leucyl-tRNA aminoacylation
GPY32_RS22435	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GPY32_RS22440	COG1466	dna polymerase III delta subunit
GPY32_RS22445	COG0799	negative regulation of ribosome biogenesis
GPY32_RS22450	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPY32_RS22455	COG0768	penicillin binding
GPY32_RS22460	COG0772	Belongs to the SEDS family
GPY32_RS22465	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPY32_RS22470	COG1686	Belongs to the peptidase S11 family
GPY32_RS22475	COG2921	Belongs to the UPF0250 family
GPY32_RS22480	COG0321	lipoyl(octanoyl) transferase activity
GPY32_RS22485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GPY32_RS22490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPY32_RS22495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPY32_RS22510	COG0366	Alpha amylase catalytic
GPY32_RS22515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY32_RS22515	COG1263	PTS System
GPY32_RS22525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPY32_RS22535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPY32_RS22540	COG2011	ABC-type metal ion transport system permease component
GPY32_RS22545	COG1464	Belongs to the NlpA lipoprotein family
GPY32_RS22550	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GPY32_RS22560	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPY32_RS22560	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPY32_RS22570	COG0745	RESPONSE REGULATOR receiver
GPY32_RS22570	COG3706	GGDEF domain
GPY32_RS22575	COG1611	Belongs to the LOG family
GPY32_RS22580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY32_RS22590	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GPY32_RS22595	COG2363	Small membrane protein
GPY32_RS22605	COG0583	DNA-binding transcription factor activity
GPY32_RS22610	COG0301	tRNA thio-modification
GPY32_RS22610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY32_RS22615	COG2885	chlorophyll binding
GPY32_RS22620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPY32_RS22625	COG1722	exodeoxyribonuclease VII activity
GPY32_RS22630	COG0142	geranyltranstransferase activity
GPY32_RS22635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPY32_RS22640	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GPY32_RS22645	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GPY32_RS22650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPY32_RS22670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY32_RS22670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY32_RS22675	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPY32_RS22680	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPY32_RS22685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPY32_RS22700	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GPY32_RS22705	COG2252	PERMEase
GPY32_RS22710	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY32_RS22735	COG0047	phosphoribosylformylglycinamidine synthase activity
GPY32_RS22735	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPY32_RS22745	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GPY32_RS22755	COG0590	tRNA wobble adenosine to inosine editing
GPY32_RS22760	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY32_RS22785	COG4969	Belongs to the N-Me-Phe pilin family
GPY32_RS22800	COG0484	heat shock protein binding
GPY32_RS22805	COG0443	Heat shock 70 kDa protein
GPY32_RS22810	COG1301	dicarboxylic acid transport
GPY32_RS22815	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPY32_RS22820	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPY32_RS22830	COG0497	DNA recombination
GPY32_RS22835	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY32_RS22840	COG2914	Belongs to the UPF0125 (RnfH) family
GPY32_RS22845	COG2867	negative regulation of translational initiation
GPY32_RS22850	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GPY32_RS22870	COG0583	DNA-binding transcription factor activity
GPY32_RS22875	COG3153	acetyltransferase
GPY32_RS22875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPY32_RS22895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GPY32_RS22900	COG2873	o-acetylhomoserine
GPY32_RS22935	COG1115	amino acid carrier protein
GPY32_RS22945	COG1584	GPR1 FUN34 yaaH family protein
GPY32_RS22955	COG1757	Na H antiporter
GPY32_RS22960	COG0519	Catalyzes the synthesis of GMP from XMP
GPY32_RS22960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GPY32_RS22965	COG0517	IMP dehydrogenase activity
GPY32_RS22965	COG0516	GMP reductase activity
GPY32_RS22970	COG1570	exodeoxyribonuclease VII activity
GPY32_RS22985	COG1160	GTP binding
GPY32_RS22990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY32_RS22995	COG2976	Protein conserved in bacteria
GPY32_RS23000	COG0124	histidyl-tRNA synthetase
GPY32_RS23005	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GPY32_RS23020	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GPY32_RS23025	COG0105	UTP biosynthetic process
GPY32_RS23030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPY32_RS23035	COG2975	iron-sulfur cluster assembly
GPY32_RS23040	COG0633	Ferredoxin
GPY32_RS23045	COG0443	Heat shock 70 kDa protein
GPY32_RS23050	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPY32_RS23060	COG0822	iron-sulfur transferase activity
GPY32_RS23065	COG1104	cysteine desulfurase activity
GPY32_RS23070	COG1959	2 iron, 2 sulfur cluster binding
GPY32_RS23080	COG0483	inositol monophosphate 1-phosphatase activity
GPY32_RS23090	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY32_RS23095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY32_RS23100	COG1862	Preprotein translocase
GPY32_RS23105	COG0343	queuine tRNA-ribosyltransferase activity
GPY32_RS23110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPY32_RS23120	COG0517	IMP dehydrogenase activity
GPY32_RS23130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GPY32_RS23140	COG0583	DNA-binding transcription factor activity
GPY32_RS23145	COG0450	alkyl hydroperoxide reductase
GPY32_RS23150	COG3142	Participates in the control of copper homeostasis
GPY32_RS23160	COG0704	Plays a role in the regulation of phosphate uptake
GPY32_RS23165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY32_RS23170	COG0581	inorganic phosphate transmembrane transporter activity
GPY32_RS23180	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GPY32_RS23185	COG0248	Ppx GppA phosphatase
GPY32_RS23195	COG5002	protein histidine kinase activity
GPY32_RS23200	COG0745	RESPONSE REGULATOR receiver
GPY32_RS23205	COG2974	May be involved in recombination
GPY32_RS23215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPY32_RS23275	COG0542	response to heat
GPY32_RS23285	COG0564	pseudouridine synthase activity
GPY32_RS23290	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY32_RS23295	COG0741	lytic transglycosylase activity
GPY32_RS23300	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY32_RS23305	COG1605	Chorismate mutase
GPY32_RS23305	COG0077	Prephenate dehydratase
GPY32_RS23310	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GPY32_RS23315	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GPY32_RS23325	COG0488	(ABC) transporter
GPY32_RS23340	COG0739	heme binding
GPY32_RS23345	COG0287	Prephenate dehydrogenase
GPY32_RS23345	COG1605	Chorismate mutase
GPY32_RS23350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY32_RS23355	COG1472	Belongs to the glycosyl hydrolase 3 family
GPY32_RS23360	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GPY32_RS23365	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPY32_RS23380	COG1966	Carbon starvation protein
GPY32_RS23385	COG3275	phosphorelay sensor kinase activity
GPY32_RS23390	COG3279	Response regulator of the LytR AlgR family
GPY32_RS23395	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GPY32_RS23400	COG1047	Peptidyl-prolyl cis-trans
GPY32_RS23405	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPY32_RS23410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPY32_RS23415	COG0196	riboflavin kinase activity
GPY32_RS23420	COG0728	peptidoglycan biosynthetic process
GPY32_RS23425	COG0268	Binds directly to 16S ribosomal RNA
GPY32_RS23435	COG0640	Transcriptional regulator
GPY32_RS23445	COG0583	DNA-binding transcription factor activity
GPY32_RS23450	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPY32_RS23460	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPY32_RS23465	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPY32_RS23470	COG0730	response to heat
GPY32_RS23480	COG0494	nUDIX hydrolase
GPY32_RS23490	COG3066	DNA modification
GPY32_RS23500	COG0667	Aldo Keto reductase
GPY32_RS23515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GPY32_RS23525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GPY32_RS23530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY32_RS23540	COG0716	FMN binding
GPY32_RS23550	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GPY32_RS23555	COG0513	Belongs to the DEAD box helicase family
GPY32_RS23560	COG3022	response to hydroperoxide
GPY32_RS23565	COG1115	amino acid carrier protein
GPY32_RS23580	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPY32_RS23590	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GPY32_RS23595	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
GPY32_RS23600	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPY32_RS23605	COG0083	homoserine kinase activity
GPY32_RS23620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPY32_RS23635	COG0745	RESPONSE REGULATOR receiver
GPY32_RS23645	COG0784	Response regulator, receiver
GPY32_RS23645	COG2198	Histidine kinase
GPY32_RS23645	COG5002	protein histidine kinase activity
GPY32_RS23650	COG3706	GGDEF domain
GPY32_RS23650	COG2203	Gaf domain
GPY32_RS23650	COG4251	negative regulation of phosphorylation
GPY32_RS23650	COG5001	Diguanylate cyclase
GPY32_RS23655	COG1242	4 iron, 4 sulfur cluster binding
GPY32_RS23660	COG0067	glutamate synthase
GPY32_RS23660	COG0070	glutamate synthase
GPY32_RS23660	COG0069	glutamate synthase activity
GPY32_RS23670	COG0070	glutamate synthase
GPY32_RS23670	COG0069	glutamate synthase activity
GPY32_RS23670	COG0067	glutamate synthase
GPY32_RS23675	COG0493	'glutamate synthase
GPY32_RS23685	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPY32_RS23695	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY32_RS23700	COG2860	membrane
GPY32_RS23705	COG0583	DNA-binding transcription factor activity
GPY32_RS23710	COG0730	response to heat
GPY32_RS23720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GPY32_RS23725	COG0505	Belongs to the CarA family
GPY32_RS23730	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GPY32_RS23735	COG0494	nUDIX hydrolase
GPY32_RS23740	COG0653	protein targeting
GPY32_RS23750	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GPY32_RS23755	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPY32_RS23760	COG0849	cell division
GPY32_RS23765	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GPY32_RS23770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPY32_RS23775	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPY32_RS23780	COG0772	Belongs to the SEDS family
GPY32_RS23785	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPY32_RS23790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPY32_RS23795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GPY32_RS23800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPY32_RS23805	COG0768	penicillin binding
GPY32_RS23810	COG3116	cell division
GPY32_RS23815	COG0275	rRNA processing
GPY32_RS23830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPY32_RS23840	COG0792	nuclease activity
GPY32_RS23845	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPY32_RS23850	COG2823	Periplasmic or secreted lipoprotein
GPY32_RS23855	COG2969	positive regulation of protein catabolic process
GPY32_RS23860	COG0625	glutathione transferase activity
GPY32_RS23865	COG2857	Cytochrome c1
GPY32_RS23870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GPY32_RS23875	COG0723	plastoquinol--plastocyanin reductase activity
GPY32_RS23880	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GPY32_RS23885	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPY32_RS23895	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GPY32_RS23905	COG3105	Protein conserved in bacteria
GPY32_RS23915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPY32_RS23920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPY32_RS23925	COG0187	DNA topoisomerase II activity
GPY32_RS23930	COG3150	esterase
GPY32_RS23940	COG3151	Protein conserved in bacteria
GPY32_RS23945	COG0494	nUDIX hydrolase
GPY32_RS23950	COG1538	Outer membrane efflux protein
GPY32_RS23955	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GPY32_RS23955	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GPY32_RS23960	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GPY32_RS23975	COG3025	triphosphatase activity
GPY32_RS23980	COG1392	Phosphate transport regulator
GPY32_RS23985	COG0306	phosphate transporter
GPY32_RS23990	COG4991	sh3 domain protein
GPY32_RS24000	COG3409	Peptidoglycan-binding domain 1 protein
GPY32_RS24000	COG3267	Type II secretory pathway component ExeA
GPY32_RS24005	COG0617	tRNA 3'-terminal CCA addition
GPY32_RS24010	COG1968	undecaprenyl-diphosphatase activity
GPY32_RS24015	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY32_RS24020	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPY32_RS24025	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GPY32_RS24030	COG0596	Alpha beta hydrolase
GPY32_RS24035	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPY32_RS24040	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GPY32_RS24045	COG1610	YqeY-like protein
GPY32_RS24050	COG0358	DNA primase activity
GPY32_RS24055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPY32_RS24065	COG1464	Belongs to the NlpA lipoprotein family
GPY32_RS24075	COG2207	Transcriptional regulator
GPY32_RS24110	COG2213	PTS system mannitol-specific
GPY32_RS24110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY32_RS24115	COG0246	Mannitol dehydrogenase
GPY32_RS24120	COG3722	fumarate hydratase activity
GPY32_RS24135	COG1461	Dihydroxyacetone kinase
GPY32_RS24140	COG2376	Dihydroxyacetone kinase
GPY32_RS24150	COG5002	protein histidine kinase activity
GPY32_RS24165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GPY32_RS24170	COG1349	DNA-binding transcription factor activity
GPY32_RS24180	COG0469	pyruvate kinase activity
GPY32_RS24190	COG3706	GGDEF domain
GPY32_RS24195	COG0440	acetolactate synthase activity
GPY32_RS24200	COG0028	Belongs to the TPP enzyme family
GPY32_RS24205	COG1022	Amp-dependent synthetase and ligase
GPY32_RS24210	COG0583	DNA-binding transcription factor activity
GPY32_RS24230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPY32_RS24235	COG0473	3-isopropylmalate dehydrogenase activity
GPY32_RS24240	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPY32_RS24245	COG0066	3-isopropylmalate dehydratase activity
GPY32_RS24255	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPY32_RS24260	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GPY32_RS24265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY32_RS24270	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GPY32_RS24275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GPY32_RS24280	COG2967	ApaG domain
GPY32_RS24285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GPY32_RS24300	COG2966	Psort location CytoplasmicMembrane, score
GPY32_RS24305	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPY32_RS24315	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GPY32_RS24320	COG0142	geranyltranstransferase activity
GPY32_RS24330	COG0039	L-malate dehydrogenase activity
GPY32_RS24365	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GPY32_RS24370	COG1178	ABC-type Fe3 transport system permease component
GPY32_RS24375	COG4143	(ABC) transporter
GPY32_RS24380	COG0163	prenyltransferase activity
GPY32_RS24385	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPY32_RS24395	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GPY32_RS24400	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GPY32_RS24410	COG2105	PFAM AIG2 family protein
GPY32_RS24415	COG2911	Protein conserved in bacteria
GPY32_RS24420	COG0729	surface antigen
GPY32_RS24425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY32_RS24435	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GPY32_RS24450	COG4181	ATPase activity
GPY32_RS24470	COG0529	Catalyzes the synthesis of activated sulfate
GPY32_RS24475	COG0471	metal ion transport
GPY32_RS24475	COG3273	potassium ion transport
GPY32_RS24485	COG2895	sulfate adenylyltransferase (ATP) activity
GPY32_RS24490	COG0175	sulfate reduction
GPY32_RS24495	COG1648	precorrin-2 dehydrogenase activity
GPY32_RS24495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPY32_RS24500	COG0737	Belongs to the 5'-nucleotidase family
GPY32_RS24510	COG0513	Belongs to the DEAD box helicase family
GPY32_RS24515	COG2153	protein acetylation
GPY32_RS24525	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY32_RS24535	COG0203	ribosomal protein L17
GPY32_RS24540	COG0202	RNA polymerase activity
GPY32_RS24550	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPY32_RS24555	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPY32_RS24565	COG0201	protein transport
GPY32_RS24570	COG0200	Binds to the 23S rRNA
GPY32_RS24575	COG1841	ribosomal large subunit assembly
GPY32_RS24590	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPY32_RS24595	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPY32_RS24600	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPY32_RS24605	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPY32_RS24610	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPY32_RS24615	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPY32_RS24620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPY32_RS24625	COG0255	Belongs to the universal ribosomal protein uL29 family
GPY32_RS24635	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPY32_RS24640	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPY32_RS24645	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPY32_RS24650	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPY32_RS24660	COG0088	Forms part of the polypeptide exit tunnel
GPY32_RS24665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPY32_RS24675	COG0254	rRNA binding
GPY32_RS24685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPY32_RS24690	COG1609	Transcriptional regulator
GPY32_RS24700	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GPY32_RS24705	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GPY32_RS24710	COG1575	Belongs to the MenA family. Type 1 subfamily
GPY32_RS24715	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPY32_RS24720	COG3074	FtsZ-dependent cytokinesis
GPY32_RS24730	COG1494	fructose-1,6-bisphosphatase
GPY32_RS24755	COG0149	triose-phosphate isomerase activity
GPY32_RS24760	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GPY32_RS24780	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPY32_RS24795	COG1482	cell wall glycoprotein biosynthetic process
GPY32_RS24815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY32_RS24820	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GPY32_RS24825	COG0438	transferase activity, transferring glycosyl groups
GPY32_RS24915	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY32_RS24925	COG1560	Kdo2-lipid A biosynthetic process
GPY32_RS24935	COG0859	PFAM glycosyl transferase family 9
GPY32_RS24945	COG1519	Transferase
GPY32_RS24955	COG1028	Short-chain dehydrogenase reductase Sdr
GPY32_RS25005	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPY32_RS25015	COG3642	lipopolysaccharide core region biosynthetic process
GPY32_RS25020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPY32_RS25025	COG0859	PFAM glycosyl transferase family 9
GPY32_RS25030	COG0463	Glycosyl transferase, family 2
GPY32_RS25045	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPY32_RS25050	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GPY32_RS25060	COG2194	sulfuric ester hydrolase activity
GPY32_RS25070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GPY32_RS25075	COG2003	Belongs to the UPF0758 family
GPY32_RS25090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPY32_RS25095	COG1309	transcriptional regulator
GPY32_RS25100	COG1560	Kdo2-lipid A biosynthetic process
GPY32_RS25105	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPY32_RS25110	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GPY32_RS25115	COG1561	YicC-like family, N-terminal region
GPY32_RS25135	COG2003	Belongs to the UPF0758 family
GPY32_RS25195	COG0328	RNA-DNA hybrid ribonuclease activity