locus-tag	class	description
GPY29_RS00005	COG0527	aspartate kinase activity
GPY29_RS00005	COG0460	homoserine dehydrogenase
GPY29_RS00010	COG0626	cystathionine gamma-synthase activity
GPY29_RS00020	COG0281	malic enzyme
GPY29_RS00030	COG2906	2 iron, 2 sulfur cluster binding
GPY29_RS00035	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPY29_RS00040	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPY29_RS00045	COG0049	tRNA binding
GPY29_RS00055	COG2168	tRNA wobble position uridine thiolation
GPY29_RS00060	COG2923	Belongs to the DsrF TusC family
GPY29_RS00065	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GPY29_RS00070	COG2964	Protein conserved in bacteria
GPY29_RS00075	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY29_RS00085	COG2900	Belongs to the SlyX family
GPY29_RS00090	COG1446	asparaginase
GPY29_RS00100	COG1047	Peptidyl-prolyl cis-trans
GPY29_RS00115	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPY29_RS00125	COG0488	(ABC) transporter
GPY29_RS00135	COG0429	hydrolase of the alpha beta-hydrolase fold
GPY29_RS00140	COG3089	Belongs to the UPF0270 family
GPY29_RS00145	COG3954	Phosphoribulokinase
GPY29_RS00150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY29_RS00160	COG1012	belongs to the aldehyde dehydrogenase family
GPY29_RS00170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPY29_RS00175	COG0512	Glutamine amidotransferase of anthranilate synthase
GPY29_RS00205	COG0180	Tryptophanyl-tRNA synthetase
GPY29_RS00210	COG0546	phosphoglycolate phosphatase activity
GPY29_RS00215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY29_RS00220	COG0557	exoribonuclease II activity
GPY29_RS00225	COG1959	2 iron, 2 sulfur cluster binding
GPY29_RS00230	COG1017	nitric oxide dioxygenase activity
GPY29_RS00230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY29_RS00235	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GPY29_RS00245	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPY29_RS00250	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GPY29_RS00255	COG0330	HflC and HflK could
GPY29_RS00260	COG0330	HflC and HflK could
GPY29_RS00265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPY29_RS00275	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPY29_RS00280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPY29_RS00290	COG0802	atpase or kinase
GPY29_RS00295	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPY29_RS00365	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GPY29_RS00370	COG1162	GTPase activity
GPY29_RS00375	COG0688	phosphatidylethanolamine metabolic process
GPY29_RS00380	COG0471	metal ion transport
GPY29_RS00395	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPY29_RS00400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY29_RS00405	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GPY29_RS00410	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GPY29_RS00415	COG1045	serine acetyltransferase
GPY29_RS00420	COG4942	peptidase
GPY29_RS00440	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GPY29_RS00450	COG1053	succinate dehydrogenase
GPY29_RS00455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPY29_RS00460	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPY29_RS00465	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPY29_RS00475	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPY29_RS00480	COG1509	lysine 2,3-aminomutase activity
GPY29_RS00490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY29_RS00505	COG0459	protein refolding
GPY29_RS00510	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPY29_RS00515	COG0534	Mate efflux family protein
GPY29_RS00520	COG0205	6-phosphofructokinase activity
GPY29_RS00530	COG3678	ATP-independent chaperone mediated protein folding
GPY29_RS00535	COG0745	RESPONSE REGULATOR receiver
GPY29_RS00540	COG2205	protein histidine kinase activity
GPY29_RS00550	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GPY29_RS00555	COG3030	protein affecting phage T7 exclusion by the F plasmid
GPY29_RS00560	COG1027	Aspartate ammonia-lyase
GPY29_RS00565	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPY29_RS00570	COG4232	protein-disulfide reductase activity
GPY29_RS00580	COG3263	regulation of cellular component size
GPY29_RS00590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY29_RS00615	COG2205	protein histidine kinase activity
GPY29_RS00615	COG0784	Response regulator, receiver
GPY29_RS00620	COG2814	Major facilitator Superfamily
GPY29_RS00635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY29_RS00640	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GPY29_RS00645	COG0511	ligase activity, forming carbon-carbon bonds
GPY29_RS00650	COG0439	Biotin carboxylase
GPY29_RS00660	COG2264	protein methyltransferase activity
GPY29_RS00665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY29_RS00670	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GPY29_RS00675	COG2814	Major facilitator Superfamily
GPY29_RS00680	COG0488	(ABC) transporter
GPY29_RS00685	COG3706	GGDEF domain
GPY29_RS00750	COG1982	Orn Lys Arg decarboxylase major
GPY29_RS00755	COG0531	amino acid
GPY29_RS00765	COG3710	Transcriptional regulator
GPY29_RS00770	COG0789	Transcriptional regulator
GPY29_RS00780	COG0138	bifunctional purine biosynthesis protein purh
GPY29_RS00790	COG0151	Belongs to the GarS family
GPY29_RS00805	COG1253	flavin adenine dinucleotide binding
GPY29_RS00810	COG3068	Protein conserved in bacteria
GPY29_RS00815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY29_RS00820	COG1573	uracil-dna glycosylase
GPY29_RS00825	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GPY29_RS00840	COG2816	NAD+ diphosphatase activity
GPY29_RS00845	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GPY29_RS00850	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPY29_RS00855	COG0085	RNA polymerase activity
GPY29_RS00860	COG0222	ribosome binding
GPY29_RS00865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPY29_RS00870	COG0081	regulation of translation
GPY29_RS00875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPY29_RS00880	COG0250	Participates in transcription elongation, termination and antitermination
GPY29_RS00885	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY29_RS00895	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPY29_RS00930	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GPY29_RS00940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPY29_RS01000	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GPY29_RS01010	COG4206	TonB-dependent receptor
GPY29_RS01015	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY29_RS01030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY29_RS01035	COG0534	Mate efflux family protein
GPY29_RS01040	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GPY29_RS01045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPY29_RS01055	COG2937	Belongs to the GPAT DAPAT family
GPY29_RS01060	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GPY29_RS01065	COG3161	chorismate lyase activity
GPY29_RS01070	COG1580	Controls the rotational direction of flagella during chemotaxis
GPY29_RS01075	COG0705	Rhomboid family
GPY29_RS01080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY29_RS01090	COG2177	Part of the ABC transporter FtsEX involved in
GPY29_RS01095	COG2884	Cell division ATP-binding protein ftsE
GPY29_RS01100	COG0552	protein localization to endoplasmic reticulum
GPY29_RS01105	COG0742	ribosomal rna small subunit methyltransferase
GPY29_RS01115	COG2095	MarC family integral membrane protein
GPY29_RS01170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY29_RS01175	COG0640	Transcriptional regulator
GPY29_RS01180	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY29_RS01185	COG1280	lysine exporter protein (LysE YggA)
GPY29_RS01190	COG2267	carboxylic ester hydrolase activity
GPY29_RS01195	COG0561	phosphatase activity
GPY29_RS01215	COG2199	diguanylate cyclase activity
GPY29_RS01215	COG2200	EAL domain
GPY29_RS01215	COG3287	FIST C domain
GPY29_RS01220	COG1011	Hydrolase
GPY29_RS01225	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GPY29_RS01235	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPY29_RS01240	COG0019	diaminopimelate decarboxylase activity
GPY29_RS01250	COG1965	Belongs to the frataxin family
GPY29_RS01255	COG3072	Adenylate cyclase
GPY29_RS01260	COG0181	hydroxymethylbilane synthase activity
GPY29_RS01265	COG1587	Uroporphyrinogen-III synthase
GPY29_RS01270	COG2959	enzyme of heme biosynthesis
GPY29_RS01275	COG3071	HemY protein
GPY29_RS01325	COG0633	Ferredoxin
GPY29_RS01330	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GPY29_RS01345	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPY29_RS01350	COG3118	belongs to the thioredoxin family
GPY29_RS01355	COG0513	Belongs to the DEAD box helicase family
GPY29_RS01360	COG0248	Ppx GppA phosphatase
GPY29_RS01365	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPY29_RS01380	COG0514	ATP-dependent DNA helicase (RecQ)
GPY29_RS01385	COG2962	Rard protein
GPY29_RS01395	COG1280	lysine exporter protein (LysE YggA)
GPY29_RS01400	COG0405	Gamma-glutamyltransferase
GPY29_RS01410	COG0210	DNA helicase
GPY29_RS01420	COG3220	belongs to the UPF0276 family
GPY29_RS01450	COG0006	proline dipeptidase activity
GPY29_RS01450	COG0006	proline dipeptidase activity
GPY29_RS01460	COG2022	thiamine diphosphate biosynthetic process
GPY29_RS01465	COG2104	thiamine diphosphate biosynthetic process
GPY29_RS01470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY29_RS01480	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GPY29_RS01485	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPY29_RS01495	COG3335	DDE superfamily endonuclease
GPY29_RS01540	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPY29_RS01550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPY29_RS01555	COG0408	coproporphyrinogen oxidase activity
GPY29_RS01560	COG0009	L-threonylcarbamoyladenylate synthase
GPY29_RS01565	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPY29_RS01570	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPY29_RS01575	COG0551	DNA topoisomerase type I activity
GPY29_RS01580	COG2922	Belongs to the Smg family
GPY29_RS01585	COG0758	DNA mediated transformation
GPY29_RS01595	COG0242	peptide deformylase activity
GPY29_RS01600	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPY29_RS01605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPY29_RS01605	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPY29_RS01610	COG0569	domain protein
GPY29_RS01615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY29_RS01625	COG1272	protein, Hemolysin III
GPY29_RS01630	COG4326	sporulation control protein
GPY29_RS01640	COG3084	Protein conserved in bacteria
GPY29_RS01650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPY29_RS01655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY29_RS01660	COG0204	Acyl-transferase
GPY29_RS01670	COG0606	chelatase, subunit chli
GPY29_RS01680	COG3978	acetolactate synthase activity
GPY29_RS01685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPY29_RS01690	COG0129	dihydroxy-acid dehydratase activity
GPY29_RS01700	COG0583	DNA-binding transcription factor activity
GPY29_RS01705	COG2814	Major facilitator Superfamily
GPY29_RS01710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY29_RS01715	COG0765	amino acid transport
GPY29_RS01720	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPY29_RS01725	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GPY29_RS01730	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPY29_RS01735	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPY29_RS01740	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPY29_RS01745	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPY29_RS01760	COG0356	it plays a direct role in the translocation of protons across the membrane
GPY29_RS01765	COG3312	ion transport
GPY29_RS01770	COG1475	DNA binding
GPY29_RS01775	COG1192	Involved in chromosome partitioning
GPY29_RS01780	COG0357	Ribosomal RNA small subunit methyltransferase G
GPY29_RS01785	COG0445	tRNA wobble uridine modification
GPY29_RS01790	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY29_RS01795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPY29_RS01800	COG0706	membrane insertase activity
GPY29_RS01805	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GPY29_RS01810	COG0594	ribonuclease P activity
GPY29_RS01820	COG1126	abc transporter atp-binding protein
GPY29_RS01845	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPY29_RS01850	COG0592	DNA-directed DNA polymerase activity
GPY29_RS01855	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPY29_RS01860	COG0187	DNA topoisomerase II activity
GPY29_RS01880	COG0071	Belongs to the small heat shock protein (HSP20) family
GPY29_RS01885	COG3977	Valine--pyruvate aminotransferase
GPY29_RS01890	COG0366	Alpha amylase catalytic
GPY29_RS01895	COG0751	glycine-tRNA ligase activity
GPY29_RS01900	COG0752	glycyl-tRNA synthetase alpha subunit
GPY29_RS01905	COG2119	membrane
GPY29_RS01915	COG0425	Belongs to the sulfur carrier protein TusA family
GPY29_RS01930	COG0604	alcohol dehydrogenase
GPY29_RS01935	COG0183	Belongs to the thiolase family
GPY29_RS01940	COG1024	Enoyl-CoA hydratase
GPY29_RS01940	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPY29_RS01945	COG1739	Uncharacterized protein family UPF0029
GPY29_RS01950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY29_RS01995	COG0583	DNA-binding transcription factor activity
GPY29_RS02000	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPY29_RS02005	COG2960	long-chain fatty acid transporting porin activity
GPY29_RS02015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY29_RS02020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY29_RS02085	COG4172	Belongs to the ABC transporter superfamily
GPY29_RS02090	COG0747	negative chemotaxis
GPY29_RS02100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY29_RS02140	COG1609	Transcriptional regulator
GPY29_RS02145	COG0583	DNA-binding transcription factor activity
GPY29_RS02155	COG2076	Multidrug Resistance protein
GPY29_RS02160	COG0129	dihydroxy-acid dehydratase activity
GPY29_RS02165	COG3265	gluconokinase activity
GPY29_RS02170	COG2610	gluconate transmembrane transporter activity
GPY29_RS02175	COG0800	Aldolase
GPY29_RS02180	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GPY29_RS02185	COG0583	DNA-binding transcription factor activity
GPY29_RS02190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY29_RS02195	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GPY29_RS02200	COG0339	signal peptide processing
GPY29_RS02205	COG1522	sequence-specific DNA binding
GPY29_RS02210	COG5002	protein histidine kinase activity
GPY29_RS02210	COG5001	Diguanylate cyclase
GPY29_RS02215	COG0742	ribosomal rna small subunit methyltransferase
GPY29_RS02225	COG0697	spore germination
GPY29_RS02230	COG0589	response to stress
GPY29_RS02235	COG1528	Iron-storage protein
GPY29_RS02245	COG2081	HI0933 family
GPY29_RS02255	COG2823	Periplasmic or secreted lipoprotein
GPY29_RS02305	COG0628	permease
GPY29_RS02320	COG1322	Protein conserved in bacteria
GPY29_RS02325	COG2226	methyltransferase
GPY29_RS02335	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GPY29_RS02340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPY29_RS02350	COG0805	protein transport
GPY29_RS02360	COG0084	hydrolase, TatD family'
GPY29_RS02385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY29_RS02385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY29_RS02395	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GPY29_RS02425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY29_RS02430	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPY29_RS02440	COG2204	response regulator
GPY29_RS02445	COG3852	Histidine kinase
GPY29_RS02455	COG0174	glutamine synthetase
GPY29_RS02475	COG1295	ribonuclease BN
GPY29_RS02480	COG1490	D-aminoacyl-tRNA deacylase activity
GPY29_RS02485	COG0456	acetyltransferase
GPY29_RS02495	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GPY29_RS02500	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPY29_RS02505	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GPY29_RS02510	COG3031	protein transport across the cell outer membrane
GPY29_RS02520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY29_RS02525	COG1459	type II secretion system
GPY29_RS02530	COG2165	general secretion pathway protein
GPY29_RS02535	COG2165	general secretion pathway protein
GPY29_RS02540	COG2165	general secretion pathway protein
GPY29_RS02545	COG4795	General secretion pathway protein
GPY29_RS02550	COG3156	type II secretion system protein K
GPY29_RS02555	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPY29_RS02560	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPY29_RS02570	COG1218	3'(2'),5'-bisphosphate nucleotidase
GPY29_RS02575	COG0494	nUDIX hydrolase
GPY29_RS02580	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GPY29_RS02580	COG0316	Belongs to the HesB IscA family
GPY29_RS02585	COG1040	competence protein
GPY29_RS02590	COG0596	Alpha beta hydrolase
GPY29_RS02600	COG2183	response to ionizing radiation
GPY29_RS02610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY29_RS02620	COG0745	RESPONSE REGULATOR receiver
GPY29_RS02625	COG2205	protein histidine kinase activity
GPY29_RS02630	COG2233	PERMEase
GPY29_RS02635	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPY29_RS02640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY29_RS02645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY29_RS02650	COG1758	RNA polymerase activity
GPY29_RS02655	COG0194	GDP metabolic process
GPY29_RS02670	COG0848	biopolymer transport protein
GPY29_RS02675	COG0811	peptide transport
GPY29_RS02700	COG4174	ABC transporter (Permease)
GPY29_RS02705	COG4239	(ABC) transporter, permease
GPY29_RS02710	COG0747	negative chemotaxis
GPY29_RS02715	COG0444	Belongs to the ABC transporter superfamily
GPY29_RS02720	COG4608	Belongs to the ABC transporter superfamily
GPY29_RS02730	COG1561	YicC-like family, N-terminal region
GPY29_RS02735	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GPY29_RS02740	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPY29_RS02745	COG1560	Kdo2-lipid A biosynthetic process
GPY29_RS02750	COG1309	transcriptional regulator
GPY29_RS02755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPY29_RS02770	COG2003	Belongs to the UPF0758 family
GPY29_RS02775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GPY29_RS02785	COG2194	sulfuric ester hydrolase activity
GPY29_RS02795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GPY29_RS02800	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPY29_RS02815	COG0463	Glycosyl transferase, family 2
GPY29_RS02820	COG0859	PFAM glycosyl transferase family 9
GPY29_RS02825	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPY29_RS02830	COG3642	lipopolysaccharide core region biosynthetic process
GPY29_RS02840	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPY29_RS02890	COG1028	Short-chain dehydrogenase reductase Sdr
GPY29_RS02900	COG1519	Transferase
GPY29_RS02910	COG0859	PFAM glycosyl transferase family 9
GPY29_RS02920	COG1560	Kdo2-lipid A biosynthetic process
GPY29_RS02930	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY29_RS02960	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
GPY29_RS02965	COG5433	transposase activity
GPY29_RS02995	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GPY29_RS02995	COG1215	transferase activity, transferring glycosyl groups
GPY29_RS03010	COG1088	dTDP-glucose 4,6-dehydratase activity
GPY29_RS03015	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GPY29_RS03020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY29_RS03040	COG1482	cell wall glycoprotein biosynthetic process
GPY29_RS03050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPY29_RS03060	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GPY29_RS03065	COG0149	triose-phosphate isomerase activity
GPY29_RS03090	COG1494	fructose-1,6-bisphosphatase
GPY29_RS03100	COG3074	FtsZ-dependent cytokinesis
GPY29_RS03105	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPY29_RS03110	COG1575	Belongs to the MenA family. Type 1 subfamily
GPY29_RS03140	COG2003	Belongs to the UPF0758 family
GPY29_RS03155	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GPY29_RS03160	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GPY29_RS03170	COG1609	Transcriptional regulator
GPY29_RS03175	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPY29_RS03185	COG0254	rRNA binding
GPY29_RS03195	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPY29_RS03200	COG0088	Forms part of the polypeptide exit tunnel
GPY29_RS03210	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPY29_RS03215	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPY29_RS03220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPY29_RS03225	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPY29_RS03235	COG0255	Belongs to the universal ribosomal protein uL29 family
GPY29_RS03240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPY29_RS03245	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPY29_RS03250	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPY29_RS03255	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPY29_RS03260	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPY29_RS03265	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPY29_RS03270	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPY29_RS03285	COG1841	ribosomal large subunit assembly
GPY29_RS03290	COG0200	Binds to the 23S rRNA
GPY29_RS03295	COG0201	protein transport
GPY29_RS03305	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPY29_RS03310	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPY29_RS03320	COG0202	RNA polymerase activity
GPY29_RS03325	COG0203	ribosomal protein L17
GPY29_RS03335	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY29_RS03345	COG2153	protein acetylation
GPY29_RS03350	COG0513	Belongs to the DEAD box helicase family
GPY29_RS03360	COG0737	Belongs to the 5'-nucleotidase family
GPY29_RS03365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPY29_RS03365	COG1648	precorrin-2 dehydrogenase activity
GPY29_RS03370	COG0175	sulfate reduction
GPY29_RS03375	COG2895	sulfate adenylyltransferase (ATP) activity
GPY29_RS03385	COG0471	metal ion transport
GPY29_RS03385	COG3273	potassium ion transport
GPY29_RS03390	COG0529	Catalyzes the synthesis of activated sulfate
GPY29_RS03410	COG4181	ATPase activity
GPY29_RS03425	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GPY29_RS03435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY29_RS03440	COG0729	surface antigen
GPY29_RS03450	COG2105	PFAM AIG2 family protein
GPY29_RS03460	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GPY29_RS03465	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GPY29_RS03475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPY29_RS03480	COG0163	prenyltransferase activity
GPY29_RS03485	COG4143	(ABC) transporter
GPY29_RS03490	COG1178	ABC-type Fe3 transport system permease component
GPY29_RS03495	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GPY29_RS03530	COG0039	L-malate dehydrogenase activity
GPY29_RS03540	COG0142	geranyltranstransferase activity
GPY29_RS03545	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GPY29_RS03555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPY29_RS03560	COG2966	Psort location CytoplasmicMembrane, score
GPY29_RS03575	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GPY29_RS03580	COG2967	ApaG domain
GPY29_RS03585	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GPY29_RS03590	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GPY29_RS03595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY29_RS03600	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GPY29_RS03605	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPY29_RS03615	COG0066	3-isopropylmalate dehydratase activity
GPY29_RS03620	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPY29_RS03625	COG0473	3-isopropylmalate dehydrogenase activity
GPY29_RS03630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPY29_RS03655	COG0583	DNA-binding transcription factor activity
GPY29_RS03660	COG1022	Amp-dependent synthetase and ligase
GPY29_RS03665	COG0028	Belongs to the TPP enzyme family
GPY29_RS03670	COG0440	acetolactate synthase activity
GPY29_RS03675	COG3706	GGDEF domain
GPY29_RS03685	COG0469	pyruvate kinase activity
GPY29_RS03695	COG1349	DNA-binding transcription factor activity
GPY29_RS03700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GPY29_RS03715	COG5002	protein histidine kinase activity
GPY29_RS03725	COG2376	Dihydroxyacetone kinase
GPY29_RS03730	COG1461	Dihydroxyacetone kinase
GPY29_RS03745	COG3722	fumarate hydratase activity
GPY29_RS03750	COG0246	Mannitol dehydrogenase
GPY29_RS03755	COG2213	PTS system mannitol-specific
GPY29_RS03755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY29_RS03830	COG3550	peptidyl-serine autophosphorylation
GPY29_RS03870	COG3550	peptidyl-serine autophosphorylation
GPY29_RS03885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY29_RS03935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPY29_RS03940	COG0358	DNA primase activity
GPY29_RS03945	COG1610	YqeY-like protein
GPY29_RS03950	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GPY29_RS03955	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPY29_RS03960	COG0596	Alpha beta hydrolase
GPY29_RS03970	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPY29_RS03975	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY29_RS03980	COG1968	undecaprenyl-diphosphatase activity
GPY29_RS03985	COG0617	tRNA 3'-terminal CCA addition
GPY29_RS03990	COG3267	Type II secretory pathway component ExeA
GPY29_RS03990	COG3409	Peptidoglycan-binding domain 1 protein
GPY29_RS04000	COG4991	sh3 domain protein
GPY29_RS04005	COG0306	phosphate transporter
GPY29_RS04010	COG1392	Phosphate transport regulator
GPY29_RS04015	COG3025	triphosphatase activity
GPY29_RS04030	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GPY29_RS04035	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GPY29_RS04035	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GPY29_RS04040	COG1538	Outer membrane efflux protein
GPY29_RS04045	COG0494	nUDIX hydrolase
GPY29_RS04050	COG3151	Protein conserved in bacteria
GPY29_RS04060	COG3150	esterase
GPY29_RS04065	COG0187	DNA topoisomerase II activity
GPY29_RS04070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPY29_RS04075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPY29_RS04085	COG3105	Protein conserved in bacteria
GPY29_RS04095	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GPY29_RS04105	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPY29_RS04110	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GPY29_RS04115	COG0723	plastoquinol--plastocyanin reductase activity
GPY29_RS04120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GPY29_RS04125	COG2857	Cytochrome c1
GPY29_RS04130	COG0625	glutathione transferase activity
GPY29_RS04135	COG2969	positive regulation of protein catabolic process
GPY29_RS04140	COG2823	Periplasmic or secreted lipoprotein
GPY29_RS04145	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPY29_RS04150	COG0792	nuclease activity
GPY29_RS04160	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPY29_RS04175	COG0275	rRNA processing
GPY29_RS04180	COG3116	cell division
GPY29_RS04185	COG0768	penicillin binding
GPY29_RS04190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPY29_RS04195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GPY29_RS04200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPY29_RS04205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPY29_RS04210	COG0772	Belongs to the SEDS family
GPY29_RS04215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPY29_RS04220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPY29_RS04225	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GPY29_RS04230	COG0849	cell division
GPY29_RS04235	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPY29_RS04240	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GPY29_RS04250	COG0653	protein targeting
GPY29_RS04255	COG0494	nUDIX hydrolase
GPY29_RS04260	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GPY29_RS04265	COG0505	Belongs to the CarA family
GPY29_RS04270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GPY29_RS04285	COG0730	response to heat
GPY29_RS04290	COG0583	DNA-binding transcription factor activity
GPY29_RS04295	COG2860	membrane
GPY29_RS04300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY29_RS04310	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPY29_RS04320	COG0493	'glutamate synthase
GPY29_RS04325	COG0067	glutamate synthase
GPY29_RS04325	COG0069	glutamate synthase activity
GPY29_RS04325	COG0070	glutamate synthase
GPY29_RS04335	COG0067	glutamate synthase
GPY29_RS04335	COG0069	glutamate synthase activity
GPY29_RS04335	COG0070	glutamate synthase
GPY29_RS04340	COG1242	4 iron, 4 sulfur cluster binding
GPY29_RS04345	COG3706	GGDEF domain
GPY29_RS04345	COG4251	negative regulation of phosphorylation
GPY29_RS04345	COG2203	Gaf domain
GPY29_RS04345	COG5001	Diguanylate cyclase
GPY29_RS04350	COG0784	Response regulator, receiver
GPY29_RS04350	COG2198	Histidine kinase
GPY29_RS04350	COG5002	protein histidine kinase activity
GPY29_RS04360	COG0745	RESPONSE REGULATOR receiver
GPY29_RS04375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPY29_RS04390	COG0083	homoserine kinase activity
GPY29_RS04395	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPY29_RS04400	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
GPY29_RS04405	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GPY29_RS04415	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPY29_RS04430	COG1115	amino acid carrier protein
GPY29_RS04435	COG3022	response to hydroperoxide
GPY29_RS04440	COG0513	Belongs to the DEAD box helicase family
GPY29_RS04445	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GPY29_RS04455	COG0716	FMN binding
GPY29_RS04465	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY29_RS04470	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GPY29_RS04480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GPY29_RS04495	COG0667	Aldo Keto reductase
GPY29_RS04505	COG3066	DNA modification
GPY29_RS04515	COG0494	nUDIX hydrolase
GPY29_RS04525	COG0730	response to heat
GPY29_RS04530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPY29_RS04535	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPY29_RS04545	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPY29_RS04550	COG0583	DNA-binding transcription factor activity
GPY29_RS04560	COG0640	Transcriptional regulator
GPY29_RS04570	COG0268	Binds directly to 16S ribosomal RNA
GPY29_RS04575	COG0728	peptidoglycan biosynthetic process
GPY29_RS04580	COG0196	riboflavin kinase activity
GPY29_RS04585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPY29_RS04590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPY29_RS04595	COG1047	Peptidyl-prolyl cis-trans
GPY29_RS04600	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GPY29_RS04605	COG3279	Response regulator of the LytR AlgR family
GPY29_RS04610	COG3275	phosphorelay sensor kinase activity
GPY29_RS04615	COG1966	Carbon starvation protein
GPY29_RS04630	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPY29_RS04635	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GPY29_RS04640	COG1472	Belongs to the glycosyl hydrolase 3 family
GPY29_RS04645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY29_RS04650	COG1605	Chorismate mutase
GPY29_RS04650	COG0287	Prephenate dehydrogenase
GPY29_RS04655	COG0739	heme binding
GPY29_RS04670	COG0488	(ABC) transporter
GPY29_RS04680	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GPY29_RS04685	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GPY29_RS04690	COG0077	Prephenate dehydratase
GPY29_RS04690	COG1605	Chorismate mutase
GPY29_RS04695	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY29_RS04700	COG0741	lytic transglycosylase activity
GPY29_RS04705	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY29_RS04710	COG0564	pseudouridine synthase activity
GPY29_RS04720	COG0542	response to heat
GPY29_RS04780	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPY29_RS04790	COG2974	May be involved in recombination
GPY29_RS04795	COG0745	RESPONSE REGULATOR receiver
GPY29_RS04800	COG5002	protein histidine kinase activity
GPY29_RS04810	COG0248	Ppx GppA phosphatase
GPY29_RS04815	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GPY29_RS04825	COG0581	inorganic phosphate transmembrane transporter activity
GPY29_RS04830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY29_RS04835	COG0704	Plays a role in the regulation of phosphate uptake
GPY29_RS04845	COG3142	Participates in the control of copper homeostasis
GPY29_RS04850	COG0450	alkyl hydroperoxide reductase
GPY29_RS04855	COG0583	DNA-binding transcription factor activity
GPY29_RS04865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GPY29_RS04875	COG0517	IMP dehydrogenase activity
GPY29_RS04885	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPY29_RS04890	COG0343	queuine tRNA-ribosyltransferase activity
GPY29_RS04895	COG1862	Preprotein translocase
GPY29_RS04900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY29_RS04905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY29_RS04915	COG0483	inositol monophosphate 1-phosphatase activity
GPY29_RS04930	COG1104	cysteine desulfurase activity
GPY29_RS04935	COG0822	iron-sulfur transferase activity
GPY29_RS04945	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPY29_RS04950	COG0443	Heat shock 70 kDa protein
GPY29_RS04955	COG0633	Ferredoxin
GPY29_RS04960	COG2975	iron-sulfur cluster assembly
GPY29_RS04965	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPY29_RS04970	COG0105	UTP biosynthetic process
GPY29_RS04975	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GPY29_RS04990	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GPY29_RS04995	COG0124	histidyl-tRNA synthetase
GPY29_RS05000	COG2976	Protein conserved in bacteria
GPY29_RS05005	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY29_RS05010	COG1160	GTP binding
GPY29_RS05025	COG1570	exodeoxyribonuclease VII activity
GPY29_RS05030	COG0516	GMP reductase activity
GPY29_RS05030	COG0517	IMP dehydrogenase activity
GPY29_RS05035	COG0519	Catalyzes the synthesis of GMP from XMP
GPY29_RS05035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GPY29_RS05040	COG1757	Na H antiporter
GPY29_RS05050	COG1584	GPR1 FUN34 yaaH family protein
GPY29_RS05060	COG1115	amino acid carrier protein
GPY29_RS05095	COG2873	o-acetylhomoserine
GPY29_RS05100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GPY29_RS05120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPY29_RS05120	COG3153	acetyltransferase
GPY29_RS05125	COG0583	DNA-binding transcription factor activity
GPY29_RS05185	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GPY29_RS05225	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GPY29_RS05230	COG2867	negative regulation of translational initiation
GPY29_RS05235	COG2914	Belongs to the UPF0125 (RnfH) family
GPY29_RS05240	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY29_RS05245	COG0497	DNA recombination
GPY29_RS05255	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPY29_RS05260	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPY29_RS05270	COG0443	Heat shock 70 kDa protein
GPY29_RS05275	COG0484	heat shock protein binding
GPY29_RS05290	COG4969	Belongs to the N-Me-Phe pilin family
GPY29_RS05315	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY29_RS05320	COG0590	tRNA wobble adenosine to inosine editing
GPY29_RS05330	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GPY29_RS05335	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPY29_RS05335	COG0047	phosphoribosylformylglycinamidine synthase activity
GPY29_RS05360	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY29_RS05365	COG2252	PERMEase
GPY29_RS05370	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GPY29_RS05385	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPY29_RS05390	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPY29_RS05395	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPY29_RS05400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY29_RS05400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY29_RS05420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPY29_RS05425	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GPY29_RS05430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GPY29_RS05435	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPY29_RS05440	COG0142	geranyltranstransferase activity
GPY29_RS05445	COG1722	exodeoxyribonuclease VII activity
GPY29_RS05450	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPY29_RS05455	COG2885	chlorophyll binding
GPY29_RS05460	COG0301	tRNA thio-modification
GPY29_RS05460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY29_RS05465	COG0583	DNA-binding transcription factor activity
GPY29_RS05475	COG2363	Small membrane protein
GPY29_RS05480	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GPY29_RS05490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY29_RS05495	COG1611	Belongs to the LOG family
GPY29_RS05500	COG3706	GGDEF domain
GPY29_RS05500	COG0745	RESPONSE REGULATOR receiver
GPY29_RS05510	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPY29_RS05510	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPY29_RS05520	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GPY29_RS05525	COG1464	Belongs to the NlpA lipoprotein family
GPY29_RS05530	COG2011	ABC-type metal ion transport system permease component
GPY29_RS05535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPY29_RS05545	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPY29_RS05555	COG1263	PTS System
GPY29_RS05555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY29_RS05560	COG0366	Alpha amylase catalytic
GPY29_RS05575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPY29_RS05580	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPY29_RS05585	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GPY29_RS05590	COG0321	lipoyl(octanoyl) transferase activity
GPY29_RS05595	COG2921	Belongs to the UPF0250 family
GPY29_RS05600	COG1686	Belongs to the peptidase S11 family
GPY29_RS05605	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPY29_RS05610	COG0772	Belongs to the SEDS family
GPY29_RS05615	COG0768	penicillin binding
GPY29_RS05620	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPY29_RS05625	COG0799	negative regulation of ribosome biogenesis
GPY29_RS05630	COG1466	dna polymerase III delta subunit
GPY29_RS05635	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GPY29_RS05640	COG0495	leucyl-tRNA aminoacylation
GPY29_RS05645	COG2888	peptidyl-tyrosine sulfation
GPY29_RS05650	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GPY29_RS05655	COG4535	Mg2 and Co2 transporter CorC
GPY29_RS05660	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPY29_RS05665	COG1702	phosphate starvation-inducible protein PhoH
GPY29_RS05670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPY29_RS05680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY29_RS05795	COG0012	GTP binding
GPY29_RS05800	COG0193	aminoacyl-tRNA hydrolase activity
GPY29_RS05805	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPY29_RS05810	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPY29_RS05815	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GPY29_RS05820	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPY29_RS05825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPY29_RS05830	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY29_RS05835	COG3094	Invasion gene expression up-regulator, SirB
GPY29_RS05840	COG2912	Transglutaminase-like superfamily
GPY29_RS05845	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GPY29_RS05850	COG0737	Belongs to the 5'-nucleotidase family
GPY29_RS05860	COG1187	pseudouridine synthase activity
GPY29_RS05865	COG2840	Smr protein MutS2
GPY29_RS05905	COG2217	Heavy metal translocating P-type atpase
GPY29_RS05905	COG2608	mercury ion transmembrane transporter activity
GPY29_RS05920	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPY29_RS05925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY29_RS05985	COG0784	Response regulator, receiver
GPY29_RS05985	COG0835	chemotaxis
GPY29_RS05990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPY29_RS05995	COG1815	bacterial-type flagellum-dependent cell motility
GPY29_RS06000	COG1558	bacterial-type flagellum-dependent cell motility
GPY29_RS06005	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPY29_RS06010	COG1749	Flagellar hook protein flgE
GPY29_RS06020	COG4787	bacterial-type flagellum-dependent cell motility
GPY29_RS06025	COG4786	Flagellar basal body rod
GPY29_RS06030	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GPY29_RS06035	COG1706	bacterial-type flagellum-dependent cell motility
GPY29_RS06040	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPY29_RS06040	COG3951	Flagellar rod assembly protein muramidase FlgJ
GPY29_RS06050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY29_RS06060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY29_RS06080	COG3778	Protein conserved in bacteria
GPY29_RS06110	COG3941	tape measure
GPY29_RS06125	COG4386	tail sheath protein
GPY29_RS06145	COG4387	Mu-like prophage protein GP36
GPY29_RS06165	COG4397	Mu-like prophage major head subunit gpT
GPY29_RS06180	COG4383	Mu-like prophage protein gp29
GPY29_RS06185	COG4373	Mu-like prophage FluMu protein gp28
GPY29_RS06200	COG0640	Transcriptional regulator
GPY29_RS06325	COG2842	Transposition protein
GPY29_RS06330	COG2801	Transposase and inactivated derivatives
GPY29_RS06335	COG3423	Transcriptional regulator
GPY29_RS06350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY29_RS06360	COG2190	(PTS) system
GPY29_RS06365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPY29_RS06370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY29_RS06380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPY29_RS06385	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GPY29_RS06390	COG3115	cell septum assembly
GPY29_RS06395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPY29_RS06420	COG0330	HflC and HflK could
GPY29_RS06425	COG3118	belongs to the thioredoxin family
GPY29_RS06435	COG0300	oxidoreductase activity
GPY29_RS06440	COG1090	epimerase
GPY29_RS06470	COG0622	Phosphoesterase
GPY29_RS06490	COG3710	Transcriptional regulator
GPY29_RS06495	COG0326	Molecular chaperone. Has ATPase activity
GPY29_RS06500	COG0563	adenylate kinase activity
GPY29_RS06505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GPY29_RS06510	COG3104	oligopeptide transport
GPY29_RS06515	COG0250	Participates in transcription elongation, termination and antitermination
GPY29_RS06520	COG0367	asparagine synthase
GPY29_RS06525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPY29_RS06525	COG4651	solute:proton antiporter activity
GPY29_RS06530	COG1940	carbohydrate kinase activity
GPY29_RS06530	COG1846	Transcriptional regulator
GPY29_RS06535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPY29_RS06545	COG2190	(PTS) system
GPY29_RS06545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY29_RS06545	COG1263	PTS System
GPY29_RS06550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY29_RS06555	COG0735	belongs to the Fur family
GPY29_RS06565	COG0716	FMN binding
GPY29_RS06575	COG0596	Alpha beta hydrolase
GPY29_RS06580	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GPY29_RS06585	COG0033	Phosphoglucomutase
GPY29_RS06595	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPY29_RS06605	COG2009	succinate dehydrogenase
GPY29_RS06610	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GPY29_RS06615	COG1053	succinate dehydrogenase
GPY29_RS06620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPY29_RS06625	COG0567	Dehydrogenase, E1 component
GPY29_RS06630	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY29_RS06635	COG0045	succinate-CoA ligase (ADP-forming) activity
GPY29_RS06645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPY29_RS06650	COG1121	(ABC) transporter
GPY29_RS06655	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GPY29_RS06660	COG4977	sequence-specific DNA binding
GPY29_RS06675	COG1918	ferrous iron import across plasma membrane
GPY29_RS06695	COG0018	arginyl-trna synthetase
GPY29_RS06705	COG3102	Protein conserved in bacteria
GPY29_RS06710	COG0788	formyltetrahydrofolate deformylase activity
GPY29_RS06715	COG1199	ATP-dependent helicase activity
GPY29_RS06720	COG1214	PFAM Peptidase M22, glycoprotease
GPY29_RS06735	COG2267	carboxylic ester hydrolase activity
GPY29_RS06740	COG0318	PFAM AMP-dependent synthetase and ligase
GPY29_RS06745	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GPY29_RS06750	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GPY29_RS06755	COG2894	cell division
GPY29_RS06760	COG0850	regulation of cytokinetic process
GPY29_RS06765	COG3100	YcgL domain-containing protein
GPY29_RS06770	COG2951	lytic endotransglycosylase activity
GPY29_RS06775	COG0583	DNA-binding transcription factor activity
GPY29_RS06780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY29_RS06785	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPY29_RS06805	COG1028	Short-chain dehydrogenase reductase Sdr
GPY29_RS06810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY29_RS06840	COG2986	histidine ammonia-lyase
GPY29_RS06845	COG1216	Glycosyl transferase, family 2
GPY29_RS06850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY29_RS06865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY29_RS06870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY29_RS06905	COG1253	flavin adenine dinucleotide binding
GPY29_RS06910	COG0513	Belongs to the DEAD box helicase family
GPY29_RS06915	COG0569	domain protein
GPY29_RS06920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY29_RS06940	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GPY29_RS06945	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPY29_RS06950	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GPY29_RS06955	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GPY29_RS06965	COG2204	response regulator
GPY29_RS06975	COG0544	peptidyl-prolyl cis-trans isomerase activity
GPY29_RS06985	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPY29_RS06990	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPY29_RS06995	COG0776	regulation of translation
GPY29_RS07000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY29_RS07005	COG1555	photosystem II stabilization
GPY29_RS07020	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GPY29_RS07025	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GPY29_RS07030	COG0436	Aminotransferase
GPY29_RS07035	COG1169	isochorismate synthase
GPY29_RS07040	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GPY29_RS07045	COG0596	Alpha beta hydrolase
GPY29_RS07050	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPY29_RS07055	COG1441	menaquinone biosynthetic process
GPY29_RS07070	COG2855	membrane
GPY29_RS07075	COG0477	Major facilitator Superfamily
GPY29_RS07120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY29_RS07125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY29_RS07155	COG1522	sequence-specific DNA binding
GPY29_RS07165	COG1946	Acyl-CoA thioesterase
GPY29_RS07170	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GPY29_RS07185	COG2199	diguanylate cyclase activity
GPY29_RS07195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY29_RS07200	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GPY29_RS07205	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GPY29_RS07215	COG0517	IMP dehydrogenase activity
GPY29_RS07215	COG0516	GMP reductase activity
GPY29_RS07245	COG0537	adenosine 5'-monophosphoramidase activity
GPY29_RS07270	COG3150	esterase
GPY29_RS07280	COG1252	NADH dehydrogenase
GPY29_RS07300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPY29_RS07310	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPY29_RS07315	COG1136	(ABC) transporter
GPY29_RS07320	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPY29_RS07330	COG2333	competence protein COMEC
GPY29_RS07330	COG0658	competence protein
GPY29_RS07335	COG1132	(ABC) transporter
GPY29_RS07340	COG1663	tetraacyldisaccharide 4'-kinase activity
GPY29_RS07350	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GPY29_RS07355	COG2719	SpoVR family
GPY29_RS07360	COG2718	Belongs to the UPF0229 family
GPY29_RS07365	COG2766	serine protein kinase
GPY29_RS07375	COG3013	Belongs to the UPF0304 family
GPY29_RS07385	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY29_RS07395	COG1882	Formate acetyltransferase
GPY29_RS07425	COG4215	(ABC) transporter
GPY29_RS07440	COG0708	Exodeoxyribonuclease III
GPY29_RS07450	COG3923	Primosomal replication protein n
GPY29_RS07455	COG0730	response to heat
GPY29_RS07460	COG1199	ATP-dependent helicase activity
GPY29_RS07470	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPY29_RS07475	COG1187	pseudouridine synthase activity
GPY29_RS07485	COG1278	Cold shock
GPY29_RS07490	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GPY29_RS07495	COG0542	response to heat
GPY29_RS07505	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPY29_RS07510	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GPY29_RS07515	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GPY29_RS07525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GPY29_RS07535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY29_RS07540	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPY29_RS07545	COG0297	glycogen (starch) synthase activity
GPY29_RS07565	COG3070	regulator of competence-specific genes
GPY29_RS07570	COG1609	Transcriptional regulator
GPY29_RS07575	COG3381	protein complex oligomerization
GPY29_RS07580	COG0745	RESPONSE REGULATOR receiver
GPY29_RS07585	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPY29_RS07590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY29_RS07595	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GPY29_RS07600	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GPY29_RS07605	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GPY29_RS07625	COG4067	protein conserved in archaea
GPY29_RS07625	COG0189	ligase activity
GPY29_RS07635	COG0500	methyltransferase
GPY29_RS07640	COG4106	trans-aconitate 2-methyltransferase activity
GPY29_RS07645	COG1801	Protein of unknown function DUF72
GPY29_RS07650	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GPY29_RS07655	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GPY29_RS07660	COG0840	transmembrane signaling receptor activity
GPY29_RS07665	COG0632	four-way junction helicase activity
GPY29_RS07670	COG2255	four-way junction helicase activity
GPY29_RS07675	COG1271	oxidase subunit
GPY29_RS07680	COG1294	oxidase, subunit
GPY29_RS07685	COG4890	Cyd operon protein YbgT
GPY29_RS07695	COG0824	Thioesterase
GPY29_RS07700	COG0811	peptide transport
GPY29_RS07715	COG0823	Involved in the tonB-independent uptake of proteins
GPY29_RS07720	COG2885	chlorophyll binding
GPY29_RS07725	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GPY29_RS07730	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GPY29_RS07740	COG3766	membrane
GPY29_RS07750	COG0754	glutathionylspermidine amidase activity
GPY29_RS07760	COG5002	protein histidine kinase activity
GPY29_RS07760	COG0784	Response regulator, receiver
GPY29_RS07775	COG0840	transmembrane signaling receptor activity
GPY29_RS07790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY29_RS07795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY29_RS07825	COG3568	Endonuclease Exonuclease Phosphatase
GPY29_RS07840	COG0583	DNA-binding transcription factor activity
GPY29_RS07850	COG0686	Belongs to the AlaDH PNT family
GPY29_RS07860	COG1674	ftsk spoiiie
GPY29_RS07865	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GPY29_RS07870	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GPY29_RS07875	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPY29_RS07890	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY29_RS07895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GPY29_RS07900	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPY29_RS07905	COG0156	8-amino-7-oxononanoate synthase activity
GPY29_RS07915	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GPY29_RS07925	COG0501	Belongs to the peptidase M48B family
GPY29_RS07935	COG0300	oxidoreductase activity
GPY29_RS07950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GPY29_RS07975	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPY29_RS07980	COG2915	High frequency lysogenization protein hflD homolog
GPY29_RS07985	COG0482	sulfurtransferase activity
GPY29_RS07995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY29_RS08005	COG1757	Na H antiporter
GPY29_RS08020	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GPY29_RS08025	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPY29_RS08030	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPY29_RS08035	COG0131	Imidazoleglycerol-phosphate dehydratase
GPY29_RS08035	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPY29_RS08040	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPY29_RS08045	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPY29_RS08050	COG0107	imidazoleglycerol-phosphate synthase activity
GPY29_RS08055	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GPY29_RS08055	COG0140	phosphoribosyl-ATP diphosphatase activity
GPY29_RS08060	COG3012	SEC-C Motif Domain Protein
GPY29_RS08070	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY29_RS08075	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY29_RS08080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPY29_RS08085	COG0215	cysteine-tRNA ligase activity
GPY29_RS08090	COG1435	thymidine kinase activity
GPY29_RS08095	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPY29_RS08120	COG2116	formate transmembrane transporter activity
GPY29_RS08130	COG0390	transport system, permease component
GPY29_RS08135	COG4459	periplasmic nitrate reductase
GPY29_RS08140	COG3005	denitrification pathway
GPY29_RS08145	COG0243	molybdopterin cofactor binding
GPY29_RS08160	COG1227	inorganic diphosphatase activity
GPY29_RS08170	COG4172	Belongs to the ABC transporter superfamily
GPY29_RS08180	COG4171	peptide transport system, permease
GPY29_RS08185	COG4168	peptide transport system, permease
GPY29_RS08195	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GPY29_RS08200	COG1842	Phage shock protein A
GPY29_RS08210	COG1983	PspC domain protein
GPY29_RS08215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY29_RS08230	COG2818	Glycosylase
GPY29_RS08235	COG5380	lipid catabolic process
GPY29_RS08240	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPY29_RS08245	COG0626	cystathionine gamma-synthase activity
GPY29_RS08255	COG0733	neurotransmitter:sodium symporter activity
GPY29_RS08265	COG0564	pseudouridine synthase activity
GPY29_RS08275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY29_RS08280	COG1151	hydroxylamine reductase activity
GPY29_RS08285	COG3604	Transcriptional regulator
GPY29_RS08300	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPY29_RS08305	COG4136	ATPase activity
GPY29_RS08310	COG4135	transport system, permease component
GPY29_RS08315	COG4134	Bacterial extracellular solute-binding protein
GPY29_RS08320	COG0398	Pfam SNARE associated Golgi protein
GPY29_RS08330	COG0493	'glutamate synthase
GPY29_RS08355	COG3313	Fe-S protein
GPY29_RS08385	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GPY29_RS08390	COG2205	protein histidine kinase activity
GPY29_RS08395	COG0745	RESPONSE REGULATOR receiver
GPY29_RS08405	COG1061	Type III restriction enzyme res subunit
GPY29_RS08410	COG1187	pseudouridine synthase activity
GPY29_RS08415	COG2814	Major facilitator Superfamily
GPY29_RS08445	COG3005	denitrification pathway
GPY29_RS08450	COG0702	epimerase
GPY29_RS08455	COG0534	Mate efflux family protein
GPY29_RS08460	COG4181	ATPase activity
GPY29_RS08475	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPY29_RS08490	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPY29_RS08495	COG3273	potassium ion transport
GPY29_RS08495	COG2985	domain, Protein
GPY29_RS08500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY29_RS08515	COG1737	Transcriptional regulator
GPY29_RS08520	COG0076	glutamate decarboxylase activity
GPY29_RS08530	COG2431	L-lysine efflux transmembrane transporter activity
GPY29_RS08545	COG3070	regulator of competence-specific genes
GPY29_RS08560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY29_RS08560	COG4191	Histidine kinase
GPY29_RS08570	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPY29_RS08575	COG3048	D-serine ammonia-lyase activity
GPY29_RS08580	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GPY29_RS08585	COG4988	ABC transporter
GPY29_RS08590	COG0492	ferredoxin-NADP+ reductase activity
GPY29_RS08610	COG3706	GGDEF domain
GPY29_RS08610	COG0745	RESPONSE REGULATOR receiver
GPY29_RS08615	COG0471	metal ion transport
GPY29_RS08620	COG2949	membrane
GPY29_RS08625	COG0281	malic enzyme
GPY29_RS08630	COG1643	Atp-dependent helicase
GPY29_RS08635	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GPY29_RS08650	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GPY29_RS08685	COG0247	lactate metabolic process
GPY29_RS08685	COG0277	FAD linked oxidase domain protein
GPY29_RS08700	COG2986	histidine ammonia-lyase
GPY29_RS08705	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GPY29_RS08710	COG0010	Belongs to the arginase family
GPY29_RS08715	COG1228	amidohydrolase
GPY29_RS08720	COG2188	Transcriptional regulator
GPY29_RS08735	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPY29_RS08745	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GPY29_RS08755	COG0393	Putative heavy-metal-binding
GPY29_RS08785	COG3706	GGDEF domain
GPY29_RS08790	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPY29_RS08795	COG0072	phenylalanine-tRNA ligase activity
GPY29_RS08795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY29_RS08810	COG0776	regulation of translation
GPY29_RS08820	COG0500	methyltransferase
GPY29_RS08825	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GPY29_RS08830	COG0295	cytidine deaminase activity
GPY29_RS08835	COG1346	cytolysis
GPY29_RS08840	COG1380	Effector of murein hydrolase LrgA
GPY29_RS08845	COG2925	Exonuclease
GPY29_RS08855	COG0702	epimerase
GPY29_RS08860	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GPY29_RS08865	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GPY29_RS08890	COG2988	succinylglutamate desuccinylase activity
GPY29_RS08895	COG4139	cobalamin transport
GPY29_RS08900	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GPY29_RS08920	COG0583	DNA-binding transcription factor activity
GPY29_RS08940	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPY29_RS08945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY29_RS08950	COG3475	LICD family
GPY29_RS08955	COG1451	nucleotide metabolic process
GPY29_RS08960	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GPY29_RS08990	COG3938	Belongs to the proline racemase family
GPY29_RS09010	COG2423	ornithine cyclodeaminase activity
GPY29_RS09015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPY29_RS09020	COG3842	ATPase activity
GPY29_RS09025	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPY29_RS09030	COG1177	transmembrane transport
GPY29_RS09040	COG3291	Pkd domain containing protein
GPY29_RS09060	COG0444	Belongs to the ABC transporter superfamily
GPY29_RS09065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY29_RS09070	COG0601	transmembrane transport
GPY29_RS09080	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY29_RS09090	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GPY29_RS09100	COG0625	glutathione transferase activity
GPY29_RS09160	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GPY29_RS09165	COG0583	DNA-binding transcription factor activity
GPY29_RS09200	COG0471	metal ion transport
GPY29_RS09205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY29_RS09205	COG4191	Histidine kinase
GPY29_RS09215	COG5001	Diguanylate cyclase
GPY29_RS09215	COG3300	MHYT domain
GPY29_RS09225	COG1280	lysine exporter protein (LysE YggA)
GPY29_RS09230	COG1328	CTP reductase activity
GPY29_RS09235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY29_RS09245	COG0861	Integral membrane protein TerC family
GPY29_RS09255	COG0739	heme binding
GPY29_RS09280	COG2204	response regulator
GPY29_RS09295	COG3501	Rhs element vgr protein
GPY29_RS09320	COG0515	serine threonine protein kinase
GPY29_RS09355	COG1522	sequence-specific DNA binding
GPY29_RS09435	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPY29_RS09450	COG0814	amino acid
GPY29_RS09475	COG1132	(ABC) transporter
GPY29_RS09480	COG1132	(ABC) transporter
GPY29_RS09510	COG0443	Heat shock 70 kDa protein
GPY29_RS09515	COG0443	Heat shock 70 kDa protein
GPY29_RS09525	COG3706	GGDEF domain
GPY29_RS09555	COG0243	molybdopterin cofactor binding
GPY29_RS09560	COG0437	4 iron, 4 sulfur cluster binding
GPY29_RS09565	COG3302	dmso reductase anchor subunit
GPY29_RS09580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPY29_RS09585	COG1643	Atp-dependent helicase
GPY29_RS09600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY29_RS09610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPY29_RS09615	COG1215	transferase activity, transferring glycosyl groups
GPY29_RS09620	COG0438	transferase activity, transferring glycosyl groups
GPY29_RS09665	COG2204	response regulator
GPY29_RS09700	COG1793	dna ligase
GPY29_RS09710	COG0534	Mate efflux family protein
GPY29_RS09715	COG0307	riboflavin synthase, alpha
GPY29_RS09730	COG2201	protein-glutamate methylesterase activity
GPY29_RS09735	COG3706	GGDEF domain
GPY29_RS09745	COG0791	NLP P60 protein
GPY29_RS09750	COG3290	protein histidine kinase activity
GPY29_RS09750	COG0840	transmembrane signaling receptor activity
GPY29_RS09790	COG1940	carbohydrate kinase activity
GPY29_RS09805	COG0746	molybdenum cofactor guanylyltransferase activity
GPY29_RS09810	COG3842	ATPase activity
GPY29_RS09830	COG2204	response regulator
GPY29_RS09835	COG4191	Histidine kinase
GPY29_RS09845	COG0488	(ABC) transporter
GPY29_RS09850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPY29_RS09875	COG3381	protein complex oligomerization
GPY29_RS09885	COG3383	formate dehydrogenase (NAD+) activity
GPY29_RS09885	COG0243	molybdopterin cofactor binding
GPY29_RS09890	COG0437	4 iron, 4 sulfur cluster binding
GPY29_RS09905	COG3209	COG3209 Rhs family protein
GPY29_RS09925	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GPY29_RS09930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY29_RS09935	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY29_RS09940	COG1177	transmembrane transport
GPY29_RS09945	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPY29_RS09950	COG3842	ATPase activity
GPY29_RS09970	COG0037	tRNA processing
GPY29_RS09980	COG0589	response to stress
GPY29_RS09985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY29_RS10000	COG2217	Heavy metal translocating P-type atpase
GPY29_RS10010	COG2010	Cytochrome c
GPY29_RS10025	COG3278	Belongs to the heme-copper respiratory oxidase family
GPY29_RS10120	COG3120	sequence-specific DNA binding
GPY29_RS10125	COG1067	ATP-dependent peptidase activity
GPY29_RS10130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY29_RS10155	COG0116	Belongs to the methyltransferase superfamily
GPY29_RS10155	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY29_RS10170	COG0167	dihydroorotate dehydrogenase activity
GPY29_RS10180	COG2902	Dehydrogenase
GPY29_RS10190	COG0308	aminopeptidase N
GPY29_RS10205	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GPY29_RS10210	COG1956	GAF domain-containing protein
GPY29_RS10215	COG1132	(ABC) transporter
GPY29_RS10220	COG2995	paraquat-inducible protein a
GPY29_RS10225	COG3008	intermembrane lipid transfer
GPY29_RS10230	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GPY29_RS10230	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPY29_RS10250	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY29_RS10255	COG1666	GTP binding
GPY29_RS10270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY29_RS10275	COG4597	amino acid ABC transporter
GPY29_RS10280	COG0765	amino acid transport
GPY29_RS10285	COG1126	abc transporter atp-binding protein
GPY29_RS10290	COG0670	Belongs to the BI1 family
GPY29_RS10300	COG2920	part of a sulfur-relay system
GPY29_RS10305	COG1254	Belongs to the acylphosphatase family
GPY29_RS10310	COG0840	transmembrane signaling receptor activity
GPY29_RS10315	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY29_RS10355	COG3706	GGDEF domain
GPY29_RS10360	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPY29_RS10365	COG0602	queuosine metabolic process
GPY29_RS10370	COG0561	phosphatase activity
GPY29_RS10395	COG2828	Protein conserved in bacteria
GPY29_RS10405	COG0372	Belongs to the citrate synthase family
GPY29_RS10410	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPY29_RS10440	COG0730	response to heat
GPY29_RS10460	COG0457	Tetratricopeptide repeat
GPY29_RS10525	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY29_RS10530	COG4790	Type iii secretion
GPY29_RS10535	COG4794	Type iii secretion
GPY29_RS10540	COG4791	protein targeting
GPY29_RS10545	COG4792	protein secretion
GPY29_RS10580	COG3177	Filamentation induced by cAMP protein fic
GPY29_RS10600	COG4669	(LipO)protein
GPY29_RS10670	COG1012	belongs to the aldehyde dehydrogenase family
GPY29_RS10675	COG3284	Transcriptional regulator
GPY29_RS10700	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPY29_RS10705	COG0363	glucosamine-6-phosphate deaminase activity
GPY29_RS10710	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPY29_RS10715	COG4565	transcriptional regulatory protein
GPY29_RS10720	COG3290	protein histidine kinase activity
GPY29_RS10735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY29_RS10750	COG1858	cytochrome C peroxidase
GPY29_RS10755	COG0527	aspartate kinase activity
GPY29_RS10760	COG0662	Cupin 2, conserved barrel domain protein
GPY29_RS10765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPY29_RS10770	COG0456	acetyltransferase
GPY29_RS10775	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY29_RS10795	COG4176	ABC-type proline glycine betaine transport system permease component
GPY29_RS10800	COG2113	Glycine betaine
GPY29_RS10810	COG1022	Amp-dependent synthetase and ligase
GPY29_RS10820	COG1028	Short-chain dehydrogenase reductase Sdr
GPY29_RS10830	COG0745	RESPONSE REGULATOR receiver
GPY29_RS10835	COG0642	Histidine kinase
GPY29_RS10840	COG1368	sulfuric ester hydrolase activity
GPY29_RS10865	COG1115	amino acid carrier protein
GPY29_RS10875	COG1280	lysine exporter protein (LysE YggA)
GPY29_RS10880	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GPY29_RS10885	COG1560	Kdo2-lipid A biosynthetic process
GPY29_RS10895	COG0531	amino acid
GPY29_RS10910	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GPY29_RS10915	COG3063	Type IV pilus biogenesis stability protein PilW
GPY29_RS10930	COG2205	protein histidine kinase activity
GPY29_RS10930	COG4999	Histidine kinase
GPY29_RS10930	COG3850	Histidine kinase
GPY29_RS10930	COG3437	response regulator, receiver
GPY29_RS10945	COG0110	maltose O-acetyltransferase activity
GPY29_RS10965	COG2315	Protein conserved in bacteria
GPY29_RS10970	COG1846	Transcriptional regulator
GPY29_RS10985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPY29_RS10995	COG1278	Cold shock
GPY29_RS11015	COG0330	HflC and HflK could
GPY29_RS11025	COG1278	Cold shock
GPY29_RS11040	COG1278	Cold shock
GPY29_RS11050	COG0583	DNA-binding transcription factor activity
GPY29_RS11120	COG0596	Alpha beta hydrolase
GPY29_RS11140	COG1204	response to ionizing radiation
GPY29_RS11195	COG2200	EAL domain
GPY29_RS11195	COG2771	luxR family
GPY29_RS11205	COG1227	inorganic diphosphatase activity
GPY29_RS11210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPY29_RS11215	COG1012	belongs to the aldehyde dehydrogenase family
GPY29_RS11220	COG2957	Belongs to the agmatine deiminase family
GPY29_RS11230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY29_RS11235	COG1012	belongs to the aldehyde dehydrogenase family
GPY29_RS11240	COG1917	Cupin 2, conserved barrel domain protein
GPY29_RS11240	COG1396	sequence-specific DNA binding
GPY29_RS11245	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GPY29_RS11255	COG0174	glutamine synthetase
GPY29_RS11260	COG1757	Na H antiporter
GPY29_RS11280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY29_RS11285	COG1280	lysine exporter protein (LysE YggA)
GPY29_RS11310	COG0346	lactoylglutathione lyase activity
GPY29_RS11440	COG1714	RDD family
GPY29_RS11685	COG4628	conserved protein (DUF2132)
GPY29_RS11920	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPY29_RS12205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY29_RS12215	COG3768	UPF0283 membrane protein
GPY29_RS12220	COG3106	COG3106 Predicted ATPase
GPY29_RS12240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY29_RS12245	COG2205	protein histidine kinase activity
GPY29_RS12245	COG0784	Response regulator, receiver
GPY29_RS12255	COG0494	nUDIX hydrolase
GPY29_RS12260	COG0814	amino acid
GPY29_RS12265	COG1760	l-serine dehydratase
GPY29_RS12270	COG2200	EAL domain
GPY29_RS12280	COG0720	synthase
GPY29_RS12310	COG1278	Cold shock
GPY29_RS12315	COG0557	exoribonuclease II activity
GPY29_RS12325	COG0840	transmembrane signaling receptor activity
GPY29_RS12330	COG0017	Asparaginyl-tRNA synthetase
GPY29_RS12340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY29_RS12365	COG1448	Aminotransferase
GPY29_RS12385	COG0840	transmembrane signaling receptor activity
GPY29_RS12390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY29_RS12395	COG1846	Transcriptional regulator
GPY29_RS12420	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GPY29_RS12435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY29_RS12440	COG3108	Peptidase M15
GPY29_RS12445	COG2989	Protein conserved in bacteria
GPY29_RS12470	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY29_RS12480	COG4235	cytochrome complex assembly
GPY29_RS12480	COG3088	subunit of a heme lyase
GPY29_RS12490	COG1138	Cytochrome C-type biogenesis protein
GPY29_RS12495	COG3301	Polysulphide reductase, NrfD
GPY29_RS12500	COG0437	4 iron, 4 sulfur cluster binding
GPY29_RS12510	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GPY29_RS12530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY29_RS12535	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY29_RS12540	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY29_RS12565	COG0019	diaminopimelate decarboxylase activity
GPY29_RS12605	COG0322	excinuclease ABC activity
GPY29_RS12610	COG2197	response regulator
GPY29_RS12615	COG0417	DNA replication proofreading
GPY29_RS12625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPY29_RS12630	COG3099	Belongs to the UPF0263 family
GPY29_RS12640	COG1187	pseudouridine synthase activity
GPY29_RS12650	COG0009	L-threonylcarbamoyladenylate synthase
GPY29_RS12655	COG0613	PHP domain protein
GPY29_RS12665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY29_RS12670	COG0512	Glutamine amidotransferase of anthranilate synthase
GPY29_RS12675	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPY29_RS12680	COG0135	phosphoribosylanthranilate isomerase activity
GPY29_RS12680	COG0134	indole-3-glycerol-phosphate synthase activity
GPY29_RS12685	COG0133	tryptophan synthase activity
GPY29_RS12690	COG0159	tryptophan synthase activity
GPY29_RS12700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY29_RS12705	COG0318	PFAM AMP-dependent synthetase and ligase
GPY29_RS12715	COG1301	dicarboxylic acid transport
GPY29_RS12735	COG2917	probably involved in intracellular septation
GPY29_RS12740	COG1607	acyl-coa hydrolase
GPY29_RS12745	COG2350	Protein conserved in bacteria
GPY29_RS12755	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPY29_RS12765	COG0583	DNA-binding transcription factor activity
GPY29_RS12780	COG5001	Diguanylate cyclase
GPY29_RS12780	COG4251	negative regulation of phosphorylation
GPY29_RS12780	COG3706	GGDEF domain
GPY29_RS12780	COG2203	Gaf domain
GPY29_RS12785	COG1032	radical SAM domain protein
GPY29_RS12790	COG0840	transmembrane signaling receptor activity
GPY29_RS12800	COG0745	RESPONSE REGULATOR receiver
GPY29_RS12805	COG5002	protein histidine kinase activity
GPY29_RS12805	COG3850	Histidine kinase
GPY29_RS12840	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPY29_RS12855	COG1335	isochorismatase
GPY29_RS12860	COG0577	efflux transmembrane transporter activity
GPY29_RS12860	COG1136	(ABC) transporter
GPY29_RS12865	COG1136	(ABC) transporter
GPY29_RS12865	COG0577	efflux transmembrane transporter activity
GPY29_RS12870	COG1136	(ABC) transporter
GPY29_RS12870	COG0577	efflux transmembrane transporter activity
GPY29_RS12880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY29_RS12910	COG3118	belongs to the thioredoxin family
GPY29_RS12915	COG4232	protein-disulfide reductase activity
GPY29_RS12955	COG2863	cytochrome
GPY29_RS12960	COG3258	Cytochrome c
GPY29_RS12965	COG2995	paraquat-inducible protein a
GPY29_RS12970	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPY29_RS12970	COG3008	intermembrane lipid transfer
GPY29_RS12980	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GPY29_RS12990	COG0463	Glycosyl transferase, family 2
GPY29_RS13005	COG4166	transmembrane transport
GPY29_RS13010	COG0284	orotidine-5'-phosphate decarboxylase activity
GPY29_RS13015	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GPY29_RS13020	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GPY29_RS13030	COG0539	negative regulation of cytoplasmic translation
GPY29_RS13035	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GPY29_RS13040	COG0616	signal peptide processing
GPY29_RS13045	COG1028	Short-chain dehydrogenase reductase Sdr
GPY29_RS13060	COG0587	DNA-directed DNA polymerase activity
GPY29_RS13065	COG0784	Response regulator, receiver
GPY29_RS13065	COG0835	chemotaxis
GPY29_RS13070	COG1940	carbohydrate kinase activity
GPY29_RS13075	COG0469	pyruvate kinase activity
GPY29_RS13080	COG4667	esterase of the alpha-beta hydrolase superfamily
GPY29_RS13095	COG0733	neurotransmitter:sodium symporter activity
GPY29_RS13115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY29_RS13115	COG1263	PTS System
GPY29_RS13120	COG0084	hydrolase, TatD family'
GPY29_RS13130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPY29_RS13135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPY29_RS13165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY29_RS13170	COG0416	fatty acid biosynthetic process
GPY29_RS13180	COG1399	metal-binding, possibly nucleic acid-binding protein
GPY29_RS13185	COG0424	maF-like protein
GPY29_RS13190	COG0564	pseudouridine synthase activity
GPY29_RS13195	COG1530	ribonuclease E activity
GPY29_RS13200	COG0659	secondary active sulfate transmembrane transporter activity
GPY29_RS13205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPY29_RS13210	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GPY29_RS13220	COG0572	uridine kinase
GPY29_RS13225	COG0489	protein tyrosine kinase activity
GPY29_RS13230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY29_RS13230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY29_RS13240	COG2186	Transcriptional regulator
GPY29_RS13245	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPY29_RS13250	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GPY29_RS13255	COG0653	protein targeting
GPY29_RS13260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY29_RS13265	COG3706	GGDEF domain
GPY29_RS13270	COG0366	Alpha amylase catalytic
GPY29_RS13275	COG1122	ATPase activity
GPY29_RS13280	COG4120	Belongs to the binding-protein-dependent transport system permease family
GPY29_RS13290	COG3092	negative regulation of chromosome organization
GPY29_RS13295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPY29_RS13300	COG0280	phosphate acetyltransferase
GPY29_RS13300	COG0857	belongs to the CobB CobQ family
GPY29_RS13305	COG3174	membrane
GPY29_RS13315	COG0435	Glutathione S-transferase
GPY29_RS13325	COG0444	Belongs to the ABC transporter superfamily
GPY29_RS13330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY29_RS13335	COG0601	transmembrane transport
GPY29_RS13345	COG0314	molybdopterin synthase activity
GPY29_RS13350	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPY29_RS13355	COG0315	cyclic pyranopterin monophosphate synthase activity
GPY29_RS13360	COG0521	Mo-molybdopterin cofactor biosynthetic process
GPY29_RS13365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPY29_RS13370	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GPY29_RS13375	COG2198	Histidine kinase
GPY29_RS13380	COG2204	response regulator
GPY29_RS13385	COG0556	nucleotide-excision repair
GPY29_RS13400	COG4657	Part of a membrane complex involved in electron transport
GPY29_RS13405	COG2878	Part of a membrane complex involved in electron transport
GPY29_RS13410	COG4656	Part of a membrane complex involved in electron transport
GPY29_RS13415	COG4658	electron transport chain
GPY29_RS13420	COG4659	FMN binding
GPY29_RS13425	COG4660	Part of a membrane complex involved in electron transport
GPY29_RS13430	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPY29_RS13435	COG0346	lactoylglutathione lyase activity
GPY29_RS13445	COG2885	chlorophyll binding
GPY29_RS13460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPY29_RS13465	COG2056	Na+-H+ antiporter family
GPY29_RS13475	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GPY29_RS13495	COG1012	belongs to the aldehyde dehydrogenase family
GPY29_RS13495	COG1454	alcohol dehydrogenase
GPY29_RS13500	COG2095	MarC family integral membrane protein
GPY29_RS13505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY29_RS13510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPY29_RS13515	COG1757	Na H antiporter
GPY29_RS13530	COG3081	Nucleoid-associated protein
GPY29_RS13535	COG3082	Protein of unknown function (DUF1414)
GPY29_RS13540	COG3083	sulfuric ester hydrolase activity
GPY29_RS13550	COG0123	including yeast histone deacetylase and acetoin utilization protein
GPY29_RS13570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY29_RS13575	COG0778	Nitroreductase
GPY29_RS13580	COG1902	pentaerythritol trinitrate reductase activity
GPY29_RS13580	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPY29_RS13585	COG0616	signal peptide processing
GPY29_RS13590	COG0252	asparaginase activity
GPY29_RS13595	COG3139	Protein of unknown function (DUF1315)
GPY29_RS13605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY29_RS13610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY29_RS13625	COG2226	methyltransferase
GPY29_RS13645	COG1785	Belongs to the alkaline phosphatase family
GPY29_RS13655	COG0346	lactoylglutathione lyase activity
GPY29_RS13660	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GPY29_RS13665	COG0668	transmembrane transport
GPY29_RS13670	COG2983	Belongs to the UPF0260 family
GPY29_RS13675	COG2261	transglycosylase associated protein
GPY29_RS13690	COG3681	Belongs to the UPF0597 family
GPY29_RS13695	COG0251	oxidation-reduction process
GPY29_RS13700	COG0814	amino acid
GPY29_RS13705	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPY29_RS13710	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPY29_RS13715	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPY29_RS13725	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPY29_RS13730	COG2832	Protein of unknown function (DUF454)
GPY29_RS13740	COG0745	RESPONSE REGULATOR receiver
GPY29_RS13745	COG0583	DNA-binding transcription factor activity
GPY29_RS13750	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPY29_RS13755	COG1286	toxin biosynthetic process
GPY29_RS13760	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GPY29_RS13765	COG0285	dihydrofolate synthase activity
GPY29_RS13770	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPY29_RS13775	COG0101	tRNA pseudouridine synthase activity
GPY29_RS13785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPY29_RS13790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY29_RS13795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPY29_RS13800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY29_RS13800	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GPY29_RS13805	COG0431	NADPH-dependent FMN reductase
GPY29_RS13820	COG3101	peptidyl-lysine hydroxylation
GPY29_RS13830	COG2860	membrane
GPY29_RS13835	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPY29_RS13840	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY29_RS13845	COG2840	Smr protein MutS2
GPY29_RS13850	COG2062	phosphohistidine phosphatase, SixA
GPY29_RS13865	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPY29_RS13865	COG1024	Enoyl-CoA hydratase
GPY29_RS13870	COG0183	Belongs to the thiolase family
GPY29_RS13885	COG2067	long-chain fatty acid transport protein
GPY29_RS13890	COG2067	long-chain fatty acid transport protein
GPY29_RS13895	COG2853	Lipoprotein
GPY29_RS13910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY29_RS13915	COG1138	Cytochrome C-type biogenesis protein
GPY29_RS13920	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GPY29_RS13925	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY29_RS13930	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY29_RS13935	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY29_RS13940	COG4133	protoheme IX ABC transporter activity
GPY29_RS13950	COG0835	chemotaxis
GPY29_RS13960	COG1192	Involved in chromosome partitioning
GPY29_RS13965	COG2201	protein-glutamate methylesterase activity
GPY29_RS13970	COG0643	Histidine kinase
GPY29_RS13970	COG2198	Histidine kinase
GPY29_RS13975	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GPY29_RS13990	COG0455	bacterial-type flagellum organization
GPY29_RS14015	COG1987	bacterial-type flagellum assembly
GPY29_RS14065	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY29_RS14075	COG1677	Flagellar hook-basal body complex protein FliE
GPY29_RS14080	COG2204	response regulator
GPY29_RS14085	COG4191	Histidine kinase
GPY29_RS14095	COG1516	flagellar protein fliS
GPY29_RS14105	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPY29_RS14110	COG1334	flagellar protein FlaG
GPY29_RS14115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY29_RS14120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY29_RS14130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY29_RS14135	COG2837	iron assimilation
GPY29_RS14165	COG1393	Belongs to the ArsC family
GPY29_RS14170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY29_RS14190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPY29_RS14195	COG2716	regulation of RNA biosynthetic process
GPY29_RS14200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPY29_RS14215	COG4783	chaperone-mediated protein folding
GPY29_RS14220	COG1393	Belongs to the ArsC family
GPY29_RS14240	COG2233	PERMEase
GPY29_RS14245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPY29_RS14250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GPY29_RS14255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPY29_RS14260	COG0121	glutamine amidotransferase
GPY29_RS14265	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPY29_RS14270	COG1960	acyl-CoA dehydrogenase activity
GPY29_RS14285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPY29_RS14290	COG0328	RNA-DNA hybrid ribonuclease activity
GPY29_RS14295	COG2226	methyltransferase
GPY29_RS14300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY29_RS14305	COG1388	LysM domain
GPY29_RS14305	COG0741	lytic transglycosylase activity
GPY29_RS14315	COG3021	interspecies interaction between organisms
GPY29_RS14320	COG0347	Belongs to the P(II) protein family
GPY29_RS14330	COG0037	tRNA processing
GPY29_RS14335	COG0825	malonyl-CoA metabolic process
GPY29_RS14340	COG0587	DNA-directed DNA polymerase activity
GPY29_RS14345	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPY29_RS14350	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY29_RS14355	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY29_RS14360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY29_RS14365	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY29_RS14370	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GPY29_RS14380	COG0750	zinc metalloprotease
GPY29_RS14385	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GPY29_RS14390	COG0575	Belongs to the CDS family
GPY29_RS14395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPY29_RS14400	COG0233	cytoplasmic translational termination
GPY29_RS14405	COG0528	UMP kinase activity
GPY29_RS14410	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPY29_RS14415	COG0052	Belongs to the universal ribosomal protein uS2 family
GPY29_RS14420	COG0024	Methionine aminopeptidase
GPY29_RS14425	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GPY29_RS14435	COG0564	pseudouridine synthase activity
GPY29_RS14440	COG3098	single-species biofilm formation
GPY29_RS14465	COG1671	Belongs to the UPF0178 family
GPY29_RS14470	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY29_RS14480	COG0254	rRNA binding
GPY29_RS14485	COG1720	tRNA m6t6A37 methyltransferase activity
GPY29_RS14490	COG0442	prolyl-tRNA aminoacylation
GPY29_RS14510	COG0733	neurotransmitter:sodium symporter activity
GPY29_RS14525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY29_RS14530	COG0514	ATP-dependent DNA helicase (RecQ)
GPY29_RS14535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPY29_RS14550	COG1477	protein flavinylation
GPY29_RS14555	COG2871	sodium ion transport
GPY29_RS14560	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY29_RS14565	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY29_RS14570	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY29_RS14575	COG1805	sodium ion transport
GPY29_RS14580	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY29_RS14585	COG0271	Belongs to the BolA IbaG family
GPY29_RS14590	COG2813	Specifically methylates the guanine in position
GPY29_RS14595	COG3056	Lipoprotein
GPY29_RS14615	COG1595	DNA-templated transcription, initiation
GPY29_RS14640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPY29_RS14645	COG0693	protein deglycase activity
GPY29_RS14650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPY29_RS14655	COG3706	GGDEF domain
GPY29_RS14660	COG2166	iron-sulfur cluster assembly
GPY29_RS14665	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GPY29_RS14670	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GPY29_RS14680	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPY29_RS14680	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPY29_RS14690	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GPY29_RS14695	COG1074	ATP-dependent DNA helicase activity
GPY29_RS14700	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GPY29_RS14720	COG3141	response to X-ray
GPY29_RS14725	COG2171	N-acyltransferase activity
GPY29_RS14730	COG0584	glycerophosphoryl diester phosphodiesterase
GPY29_RS14735	COG2271	Major facilitator Superfamily
GPY29_RS14750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPY29_RS14755	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPY29_RS14760	COG1349	DNA-binding transcription factor activity
GPY29_RS14765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPY29_RS14770	COG0598	Magnesium transport protein CorA
GPY29_RS14785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY29_RS14790	COG1609	Transcriptional regulator
GPY29_RS14795	COG2176	DNA-directed DNA polymerase activity
GPY29_RS14810	COG2017	converts alpha-aldose to the beta-anomer
GPY29_RS14815	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPY29_RS14825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPY29_RS14835	COG1609	Transcriptional regulator
GPY29_RS14840	COG3250	beta-galactosidase activity
GPY29_RS14845	COG2731	YhcH YjgK YiaL family protein
GPY29_RS14850	COG0531	amino acid
GPY29_RS14855	COG0583	DNA-binding transcription factor activity
GPY29_RS14920	COG4964	Belongs to the GSP D family
GPY29_RS14945	COG2169	Transcriptional regulator
GPY29_RS14950	COG1022	Amp-dependent synthetase and ligase
GPY29_RS14960	COG0583	DNA-binding transcription factor activity
GPY29_RS14965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPY29_RS14970	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPY29_RS14980	COG0560	Phosphoserine phosphatase
GPY29_RS14990	COG0813	purine-nucleoside phosphorylase activity
GPY29_RS14995	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPY29_RS15000	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GPY29_RS15005	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPY29_RS15010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY29_RS15015	COG0084	hydrolase, TatD family'
GPY29_RS15025	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GPY29_RS15045	COG3153	acetyltransferase
GPY29_RS15070	COG0534	Mate efflux family protein
GPY29_RS15085	COG1185	polyribonucleotide nucleotidyltransferase activity
GPY29_RS15090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPY29_RS15095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPY29_RS15100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPY29_RS15105	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPY29_RS15110	COG0195	Participates in both transcription termination and antitermination
GPY29_RS15115	COG0779	Required for maturation of 30S ribosomal subunits
GPY29_RS15130	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY29_RS15140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY29_RS15145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPY29_RS15150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPY29_RS15155	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GPY29_RS15160	COG1534	Rna-binding protein
GPY29_RS15165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY29_RS15170	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPY29_RS15175	COG2027	D-alanyl-D-alanine carboxypeptidase
GPY29_RS15185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPY29_RS15190	COG0739	heme binding
GPY29_RS15195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY29_RS15205	COG0316	Belongs to the HesB IscA family
GPY29_RS15210	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GPY29_RS15215	COG0628	permease
GPY29_RS15220	COG2813	Specifically methylates the guanine in position
GPY29_RS15225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY29_RS15225	COG0784	Response regulator, receiver
GPY29_RS15225	COG2198	Histidine kinase
GPY29_RS15225	COG2205	protein histidine kinase activity
GPY29_RS15230	COG0747	negative chemotaxis
GPY29_RS15240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY29_RS15245	COG0444	Belongs to the ABC transporter superfamily
GPY29_RS15250	COG4608	Belongs to the ABC transporter superfamily
GPY29_RS15260	COG2971	BadF BadG BcrA BcrD
GPY29_RS15275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY29_RS15280	COG3842	ATPase activity
GPY29_RS15290	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY29_RS15295	COG0004	ammonium transporteR
GPY29_RS15305	COG3112	Uncharacterised protein family (UPF0231)
GPY29_RS15310	COG1049	propionate catabolic process, 2-methylcitrate cycle
GPY29_RS15315	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPY29_RS15320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPY29_RS15325	COG1643	Atp-dependent helicase
GPY29_RS15330	COG1489	DNA binding
GPY29_RS15335	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY29_RS15345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY29_RS15360	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY29_RS15365	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GPY29_RS15370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GPY29_RS15380	COG1560	Kdo2-lipid A biosynthetic process
GPY29_RS15385	COG0842	Transport permease protein
GPY29_RS15390	COG1131	(ABC) transporter
GPY29_RS15400	COG0659	secondary active sulfate transmembrane transporter activity
GPY29_RS15405	COG0288	reversible hydration of carbon dioxide
GPY29_RS15420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY29_RS15425	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY29_RS15430	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GPY29_RS15435	COG2186	Transcriptional regulator
GPY29_RS15445	COG0157	Belongs to the NadC ModD family
GPY29_RS15455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY29_RS15460	COG1459	type II secretion system
GPY29_RS15470	COG0237	dephospho-CoA kinase activity
GPY29_RS15475	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GPY29_RS15480	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GPY29_RS15485	COG0335	large ribosomal subunit rRNA binding
GPY29_RS15490	COG0336	Belongs to the RNA methyltransferase TrmD family
GPY29_RS15495	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPY29_RS15500	COG0228	four-way junction DNA binding
GPY29_RS15505	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPY29_RS15510	COG4137	Cytochrome C assembly protein
GPY29_RS15515	COG4536	flavin adenine dinucleotide binding
GPY29_RS15520	COG1854	S-ribosylhomocysteine lyase activity
GPY29_RS15530	COG2918	glutathione biosynthetic process
GPY29_RS15535	COG0612	Peptidase, M16
GPY29_RS15540	COG1238	metal cluster binding
GPY29_RS15545	COG1063	alcohol dehydrogenase
GPY29_RS15550	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPY29_RS15555	COG0511	ligase activity, forming carbon-carbon bonds
GPY29_RS15555	COG5016	pyruvate
GPY29_RS15560	COG3630	sodium ion export across plasma membrane
GPY29_RS15625	COG0527	aspartate kinase activity
GPY29_RS15630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPY29_RS15635	COG2137	regulation of response to DNA damage stimulus
GPY29_RS15640	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPY29_RS15645	COG1546	Belongs to the CinA family
GPY29_RS15650	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPY29_RS15665	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GPY29_RS15670	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GPY29_RS15675	COG0585	pseudouridine synthase activity
GPY29_RS15680	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GPY29_RS15685	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPY29_RS15690	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GPY29_RS15695	COG0148	phosphopyruvate hydratase activity
GPY29_RS15700	COG0504	CTP synthase activity
GPY29_RS15705	COG3956	TIGRFAM MazG family protein
GPY29_RS15710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY29_RS15720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY29_RS15730	COG0736	holo-[acyl-carrier-protein] synthase activity
GPY29_RS15735	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GPY29_RS15740	COG1381	Involved in DNA repair and RecF pathway recombination
GPY29_RS15745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPY29_RS15750	COG0571	ribonuclease III activity
GPY29_RS15755	COG0681	Belongs to the peptidase S26 family
GPY29_RS15760	COG0481	GTPase activity
GPY29_RS15765	COG3086	response to oxidative stress
GPY29_RS15775	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GPY29_RS15780	COG1595	DNA-templated transcription, initiation
GPY29_RS15790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GPY29_RS15800	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GPY29_RS15805	COG0354	folic acid binding
GPY29_RS15820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY29_RS15825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY29_RS15830	COG3079	Belongs to the UPF0149 family
GPY29_RS15840	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPY29_RS15850	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPY29_RS15855	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GPY29_RS15860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY29_RS15870	COG0583	DNA-binding transcription factor activity
GPY29_RS15880	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPY29_RS15885	COG0668	transmembrane transport
GPY29_RS15890	COG0191	fructose-bisphosphate aldolase activity
GPY29_RS15895	COG0126	phosphoglycerate kinase activity
GPY29_RS15900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY29_RS15905	COG4771	TonB-dependent receptor
GPY29_RS15910	COG0583	DNA-binding transcription factor activity
GPY29_RS15915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPY29_RS15925	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPY29_RS15935	COG3091	SprT-like family
GPY29_RS15940	COG2356	endonuclease I
GPY29_RS15945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GPY29_RS15950	COG0189	ligase activity
GPY29_RS15955	COG1678	Uncharacterized ACR, COG1678
GPY29_RS15960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPY29_RS15975	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPY29_RS15980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPY29_RS15985	COG0762	integral membrane protein
GPY29_RS15990	COG1872	DUF167
GPY29_RS16000	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPY29_RS16005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY29_RS16010	COG2066	Belongs to the glutaminase family
GPY29_RS16020	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GPY29_RS16030	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GPY29_RS16035	COG0741	lytic transglycosylase activity
GPY29_RS16105	COG1012	belongs to the aldehyde dehydrogenase family
GPY29_RS16165	COG3394	polysaccharide catabolic process
GPY29_RS16170	COG1486	melibiose metabolic process
GPY29_RS16175	COG1447	Phosphotransferase system cellobiose-specific component IIA
GPY29_RS16180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPY29_RS16185	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPY29_RS16190	COG0726	polysaccharide deacetylase
GPY29_RS16200	COG1028	Short-chain dehydrogenase reductase Sdr
GPY29_RS16205	COG4325	translation initiation factor activity
GPY29_RS16215	COG0795	lipopolysaccharide-transporting ATPase activity
GPY29_RS16220	COG0795	lipopolysaccharide-transporting ATPase activity
GPY29_RS16225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPY29_RS16230	COG2927	DNA polymerase III (CHI subunit)
GPY29_RS16235	COG0525	valine-tRNA ligase activity
GPY29_RS16265	COG2235	arginine
GPY29_RS16270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPY29_RS16280	COG0540	Belongs to the ATCase OTCase family
GPY29_RS16285	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GPY29_RS16290	COG0251	oxidation-reduction process
GPY29_RS16295	COG0204	Acyl-transferase
GPY29_RS16300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPY29_RS16305	COG5007	Belongs to the BolA IbaG family
GPY29_RS16315	COG2854	intermembrane phospholipid transfer
GPY29_RS16320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPY29_RS16325	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GPY29_RS16330	COG1127	ABC transporter
GPY29_RS16340	COG0517	IMP dehydrogenase activity
GPY29_RS16340	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GPY29_RS16350	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GPY29_RS16355	COG1137	ATPase activity
GPY29_RS16365	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY29_RS16370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY29_RS16375	COG1660	Displays ATPase and GTPase activities
GPY29_RS16380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY29_RS16385	COG2239	Acts as a magnesium transporter
GPY29_RS16390	COG0312	modulator of DNA gyrase
GPY29_RS16395	COG3028	Belongs to the UPF0307 family
GPY29_RS16400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY29_RS16405	COG0564	pseudouridine synthase activity
GPY29_RS16420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GPY29_RS16425	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GPY29_RS16430	COG0312	modulator of DNA gyrase
GPY29_RS16435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPY29_RS16440	COG3164	Protein of unknown function
GPY29_RS16445	COG1530	ribonuclease E activity
GPY29_RS16450	COG0424	maF-like protein
GPY29_RS16455	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GPY29_RS16460	COG1792	Involved in formation and maintenance of cell shape
GPY29_RS16465	COG1077	Cell shape determining protein MreB Mrl
GPY29_RS16510	COG1459	type II secretion system
GPY29_RS16515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY29_RS16525	COG3267	Type II secretory pathway component ExeA
GPY29_RS16525	COG3409	Peptidoglycan-binding domain 1 protein
GPY29_RS16550	COG2199	diguanylate cyclase activity
GPY29_RS16550	COG2200	EAL domain
GPY29_RS16555	COG0629	single-stranded DNA binding
GPY29_RS16570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPY29_RS16580	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPY29_RS16585	COG0527	aspartate kinase activity
GPY29_RS16590	COG0646	methionine synthase
GPY29_RS16590	COG1410	methionine synthase
GPY29_RS16600	COG1943	Transposase
GPY29_RS16655	COG0175	sulfate reduction
GPY29_RS16660	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPY29_RS16665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY29_RS16690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY29_RS16700	COG0735	belongs to the Fur family
GPY29_RS16710	COG0166	Belongs to the GPI family
GPY29_RS16715	COG0432	Pfam Uncharacterised protein family UPF0047
GPY29_RS16725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY29_RS16730	COG0305	Participates in initiation and elongation during chromosome replication
GPY29_RS16740	COG0359	binds to the 23S rRNA
GPY29_RS16750	COG2965	DNA replication, synthesis of RNA primer
GPY29_RS16755	COG0360	Binds together with S18 to 16S ribosomal RNA
GPY29_RS16760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPY29_RS16765	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GPY29_RS16775	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPY29_RS16780	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GPY29_RS16810	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GPY29_RS16820	COG0678	peroxiredoxin activity
GPY29_RS16820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY29_RS16835	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPY29_RS16835	COG0165	Argininosuccinate lyase
GPY29_RS16840	COG0137	argininosuccinate synthase activity
GPY29_RS16845	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPY29_RS16850	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPY29_RS16855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY29_RS16860	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GPY29_RS16870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPY29_RS16995	COG3833	ABC-type maltose transport systems, permease component
GPY29_RS17000	COG1175	transmembrane transport
GPY29_RS17010	COG3842	ATPase activity
GPY29_RS17040	COG0438	transferase activity, transferring glycosyl groups
GPY29_RS17075	COG1309	transcriptional regulator
GPY29_RS17080	COG2130	NADP-dependent
GPY29_RS17090	COG0753	catalase activity
GPY29_RS17095	COG2084	Dehydrogenase
GPY29_RS17100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY29_RS17105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY29_RS17115	COG2207	Transcriptional regulator
GPY29_RS17120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY29_RS17120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY29_RS17120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY29_RS17135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY29_RS17140	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GPY29_RS17150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY29_RS17155	COG0569	domain protein
GPY29_RS17165	COG5002	protein histidine kinase activity
GPY29_RS17170	COG1132	(ABC) transporter
GPY29_RS17175	COG4774	siderophore transport
GPY29_RS17180	COG1120	ATPase activity
GPY29_RS17185	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GPY29_RS17235	COG2197	response regulator
GPY29_RS17245	COG0840	transmembrane signaling receptor activity
GPY29_RS17255	COG0714	Associated with various cellular activities
GPY29_RS17275	COG2304	oxidoreductase activity
GPY29_RS17290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY29_RS17295	COG0581	inorganic phosphate transmembrane transporter activity
GPY29_RS17300	COG0573	inorganic phosphate transmembrane transporter activity
GPY29_RS17305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY29_RS17335	COG1770	oligopeptidase
GPY29_RS17340	COG0513	Belongs to the DEAD box helicase family
GPY29_RS17350	COG1376	ErfK ybiS ycfS ynhG family protein
GPY29_RS17350	COG1388	LysM domain
GPY29_RS17355	COG0415	Belongs to the DNA photolyase family
GPY29_RS17360	COG0789	Transcriptional regulator
GPY29_RS17365	COG3272	Protein of unknown function (DUF1722)
GPY29_RS17375	COG0813	purine-nucleoside phosphorylase activity
GPY29_RS17390	COG3706	GGDEF domain
GPY29_RS17400	COG1566	PFAM secretion protein HlyD family protein
GPY29_RS17405	COG4720	Psort location CytoplasmicMembrane, score
GPY29_RS17410	COG1122	ATPase activity
GPY29_RS17425	COG0348	domain, Protein
GPY29_RS17430	COG0437	4 iron, 4 sulfur cluster binding
GPY29_RS17435	COG1247	-acetyltransferase
GPY29_RS17465	COG1067	ATP-dependent peptidase activity
GPY29_RS17475	COG4172	Belongs to the ABC transporter superfamily
GPY29_RS17480	COG1505	serine-type exopeptidase activity
GPY29_RS17485	COG0583	DNA-binding transcription factor activity
GPY29_RS17490	COG1620	l-lactate permease
GPY29_RS17495	COG1304	FMN binding
GPY29_RS17505	COG0668	transmembrane transport
GPY29_RS17530	COG1063	alcohol dehydrogenase
GPY29_RS17535	COG0156	8-amino-7-oxononanoate synthase activity
GPY29_RS17545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY29_RS17565	COG0745	RESPONSE REGULATOR receiver
GPY29_RS17600	COG0346	lactoylglutathione lyase activity
GPY29_RS17620	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPY29_RS17660	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY29_RS17675	COG2204	response regulator
GPY29_RS17700	COG1987	bacterial-type flagellum assembly
GPY29_RS17710	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GPY29_RS17725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY29_RS17735	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPY29_RS17740	COG1516	flagellar protein fliS
GPY29_RS17755	COG1580	Controls the rotational direction of flagella during chemotaxis
GPY29_RS17760	COG1191	sigma factor activity
GPY29_RS17765	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPY29_RS17770	COG1360	Flagellar Motor Protein
GPY29_RS17825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY29_RS17830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPY29_RS17840	COG0454	-acetyltransferase
GPY29_RS17850	COG2814	Major facilitator Superfamily
GPY29_RS17895	COG0628	permease
GPY29_RS17900	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPY29_RS17910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY29_RS17920	COG4628	conserved protein (DUF2132)
GPY29_RS17925	COG0583	DNA-binding transcription factor activity
GPY29_RS17950	COG1686	Belongs to the peptidase S11 family
GPY29_RS17970	COG3397	chitin binding
GPY29_RS17975	COG4667	esterase of the alpha-beta hydrolase superfamily
GPY29_RS18000	COG0489	protein tyrosine kinase activity
GPY29_RS18000	COG3206	protein involved in exopolysaccharide biosynthesis
GPY29_RS18015	COG0583	DNA-binding transcription factor activity
GPY29_RS18025	COG1301	dicarboxylic acid transport
GPY29_RS18040	COG3339	Conserved Protein
GPY29_RS18045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY29_RS18050	COG0700	Nucleoside recognition
GPY29_RS18055	COG3366	ferrous iron transmembrane transporter activity
GPY29_RS18070	COG0366	Alpha amylase catalytic
GPY29_RS18075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPY29_RS18080	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GPY29_RS18085	COG1640	4-alpha-glucanotransferase
GPY29_RS18090	COG0058	SHG alpha-glucan phosphorylase activity
GPY29_RS18105	COG2909	trisaccharide binding
GPY29_RS18120	COG1999	signal sequence binding
GPY29_RS18130	COG1263	PTS System
GPY29_RS18130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY29_RS18135	COG1162	GTPase activity
GPY29_RS18140	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GPY29_RS18150	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GPY29_RS18160	COG0531	amino acid
GPY29_RS18165	COG1982	Orn Lys Arg decarboxylase major
GPY29_RS18185	COG2356	endonuclease I
GPY29_RS18210	COG4580	involved in the transport of maltose and maltodextrins
GPY29_RS18235	COG0739	heme binding
GPY29_RS18245	COG0612	Peptidase, M16
GPY29_RS18250	COG0840	transmembrane signaling receptor activity
GPY29_RS18255	COG1120	ATPase activity
GPY29_RS18260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY29_RS18265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY29_RS18270	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GPY29_RS18275	COG4772	TonB-dependent receptor
GPY29_RS18300	COG4264	IucA IucC family
GPY29_RS18305	COG0019	diaminopimelate decarboxylase activity
GPY29_RS18310	COG1653	transport
GPY29_RS18320	COG0745	RESPONSE REGULATOR receiver
GPY29_RS18345	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPY29_RS18350	COG1129	ABC transporter
GPY29_RS18355	COG1879	ABC-type sugar transport system periplasmic component
GPY29_RS18360	COG1069	ribulokinase activity
GPY29_RS18370	COG2160	L-arabinose isomerase activity
GPY29_RS18395	COG1764	response to oxidative stress
GPY29_RS18400	COG1846	Transcriptional regulator
GPY29_RS18405	COG0450	alkyl hydroperoxide reductase
GPY29_RS18410	COG3634	alkyl hydroperoxide reductase activity
GPY29_RS18440	COG1595	DNA-templated transcription, initiation
GPY29_RS18455	COG0840	transmembrane signaling receptor activity
GPY29_RS18475	COG2258	MOSC domain
GPY29_RS18480	COG0513	Belongs to the DEAD box helicase family
GPY29_RS18510	COG1132	(ABC) transporter
GPY29_RS18555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY29_RS18585	COG0259	pyridoxamine-phosphate oxidase activity
GPY29_RS18635	COG4166	transmembrane transport
GPY29_RS18655	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPY29_RS18660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY29_RS18660	COG1263	PTS System
GPY29_RS18665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPY29_RS18670	COG3340	Belongs to the peptidase S51 family
GPY29_RS18690	COG1444	tRNA N-acetyltransferase activity
GPY29_RS18715	COG4608	Belongs to the ABC transporter superfamily
GPY29_RS18720	COG0444	Belongs to the ABC transporter superfamily
GPY29_RS18730	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
GPY29_RS18730	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY29_RS18755	COG0217	transcriptional regulatory protein
GPY29_RS18760	COG0772	Belongs to the SEDS family
GPY29_RS18795	COG3275	phosphorelay sensor kinase activity
GPY29_RS18800	COG3279	Response regulator of the LytR AlgR family
GPY29_RS18810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPY29_RS18845	COG0786	glutamate:sodium symporter activity
GPY29_RS18855	COG1131	(ABC) transporter
GPY29_RS18860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY29_RS18865	COG0786	glutamate:sodium symporter activity
GPY29_RS18880	COG0363	glucosamine-6-phosphate deaminase activity
GPY29_RS18900	COG1741	Belongs to the pirin family
GPY29_RS18905	COG2259	Doxx family
GPY29_RS18920	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GPY29_RS18925	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPY29_RS18935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPY29_RS18975	COG3123	guanosine phosphorylase activity
GPY29_RS18985	COG5001	Diguanylate cyclase
GPY29_RS18995	COG0534	Mate efflux family protein
GPY29_RS19000	COG0564	pseudouridine synthase activity
GPY29_RS19015	COG0583	DNA-binding transcription factor activity
GPY29_RS19020	COG0561	phosphatase activity
GPY29_RS19030	COG2199	diguanylate cyclase activity
GPY29_RS19045	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GPY29_RS19050	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GPY29_RS19055	COG0583	DNA-binding transcription factor activity
GPY29_RS19060	COG2375	cellular response to nickel ion
GPY29_RS19090	COG1357	PFAM Pentapeptide repeats (8 copies)
GPY29_RS19095	COG3047	cAMP biosynthetic process
GPY29_RS19125	COG3408	Glycogen debranching enzyme
GPY29_RS19125	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GPY29_RS19130	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GPY29_RS19170	COG3835	regulator
GPY29_RS19175	COG2610	gluconate transmembrane transporter activity
GPY29_RS19180	COG1929	Belongs to the glycerate kinase type-1 family
GPY29_RS19185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY29_RS19205	COG0456	acetyltransferase
GPY29_RS19220	COG1028	Short-chain dehydrogenase reductase Sdr
GPY29_RS19230	COG3005	denitrification pathway
GPY29_RS19235	COG0243	molybdopterin cofactor binding
GPY29_RS19245	COG0352	thiamine-phosphate diphosphorylase activity
GPY29_RS19250	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GPY29_RS19255	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GPY29_RS19260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GPY29_RS19265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GPY29_RS19270	COG1116	anion transmembrane transporter activity
GPY29_RS19275	COG0351	phosphomethylpyrimidine kinase
GPY29_RS19285	COG0312	modulator of DNA gyrase
GPY29_RS19290	COG0312	modulator of DNA gyrase
GPY29_RS19295	COG1901	pseudouridine methyltransferase
GPY29_RS19355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY29_RS19365	COG0584	glycerophosphoryl diester phosphodiesterase
GPY29_RS19375	COG0745	RESPONSE REGULATOR receiver
GPY29_RS19395	COG0811	peptide transport
GPY29_RS19400	COG0811	peptide transport
GPY29_RS19405	COG0848	biopolymer transport protein
GPY29_RS19445	COG0803	Belongs to the bacterial solute-binding protein 9 family
GPY29_RS19450	COG1121	(ABC) transporter
GPY29_RS19455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPY29_RS19470	COG1770	oligopeptidase
GPY29_RS19475	COG2814	Major facilitator Superfamily
GPY29_RS19480	COG0010	Belongs to the arginase family
GPY29_RS19485	COG1166	arginine decarboxylase activity
GPY29_RS19495	COG4067	protein conserved in archaea
GPY29_RS19495	COG0189	ligase activity
GPY29_RS19500	COG0189	ligase activity
GPY29_RS19510	COG0583	DNA-binding transcription factor activity
GPY29_RS19555	COG3706	GGDEF domain
GPY29_RS19585	COG0579	oxidoreductase
GPY29_RS19595	COG3033	Beta-eliminating lyase
GPY29_RS19615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY29_RS19630	COG3706	GGDEF domain
GPY29_RS19635	COG0840	transmembrane signaling receptor activity
GPY29_RS19650	COG3706	GGDEF domain
GPY29_RS19655	COG0415	Belongs to the DNA photolyase family
GPY29_RS19660	COG3046	protein related to deoxyribodipyrimidine photolyase
GPY29_RS19675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY29_RS19675	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY29_RS19680	COG1765	OsmC-like protein
GPY29_RS19685	COG0110	maltose O-acetyltransferase activity
GPY29_RS19725	COG1011	Hydrolase
GPY29_RS19740	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GPY29_RS19750	COG2067	long-chain fatty acid transport protein
GPY29_RS19755	COG3240	lipase activity
GPY29_RS19785	COG1609	Transcriptional regulator
GPY29_RS19790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY29_RS19800	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPY29_RS19805	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY29_RS19815	COG3842	ATPase activity
GPY29_RS19840	COG2990	Protein conserved in bacteria
GPY29_RS19850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY29_RS19855	COG2866	Carboxypeptidase
GPY29_RS19870	COG0583	DNA-binding transcription factor activity
GPY29_RS19895	COG1760	l-serine dehydratase
GPY29_RS19915	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPY29_RS19925	COG0741	lytic transglycosylase activity
GPY29_RS19945	COG1815	bacterial-type flagellum-dependent cell motility
GPY29_RS19950	COG1558	bacterial-type flagellum-dependent cell motility
GPY29_RS19955	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPY29_RS19960	COG1749	Flagellar hook protein flgE
GPY29_RS19965	COG4787	bacterial-type flagellum-dependent cell motility
GPY29_RS19970	COG4786	Flagellar basal body rod
GPY29_RS19975	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GPY29_RS19980	COG1706	bacterial-type flagellum-dependent cell motility
GPY29_RS19995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY29_RS20015	COG1304	FMN binding
GPY29_RS20035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY29_RS20045	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPY29_RS20050	COG0459	protein refolding
GPY29_RS20065	COG1280	lysine exporter protein (LysE YggA)
GPY29_RS20085	COG1309	transcriptional regulator
GPY29_RS20095	COG0737	Belongs to the 5'-nucleotidase family
GPY29_RS20105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY29_RS20120	COG0346	lactoylglutathione lyase activity
GPY29_RS20125	COG1349	DNA-binding transcription factor activity
GPY29_RS20145	COG1335	isochorismatase
GPY29_RS20155	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPY29_RS20185	COG0583	DNA-binding transcription factor activity
GPY29_RS20200	COG3713	MltA-interacting MipA family protein
GPY29_RS20210	COG3015	lipoprotein NlpE involved in copper resistance
GPY29_RS20220	COG1342	Belongs to the UPF0251 family
GPY29_RS20255	COG4948	Mandelate Racemase Muconate Lactonizing
GPY29_RS20265	COG0583	DNA-binding transcription factor activity
GPY29_RS20315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPY29_RS20350	COG3842	ATPase activity
GPY29_RS20380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY29_RS20400	COG3706	GGDEF domain
GPY29_RS20420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY29_RS20435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY29_RS20440	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPY29_RS20460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPY29_RS20460	COG0574	Belongs to the PEP-utilizing enzyme family
GPY29_RS20465	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GPY29_RS20470	COG0252	asparaginase activity
GPY29_RS20480	COG0583	DNA-binding transcription factor activity
GPY29_RS20495	COG3122	Protein conserved in bacteria
GPY29_RS20510	COG1028	Short-chain dehydrogenase reductase Sdr
GPY29_RS20520	COG1063	alcohol dehydrogenase
GPY29_RS20525	COG1902	pentaerythritol trinitrate reductase activity
GPY29_RS20540	COG0583	DNA-binding transcription factor activity
GPY29_RS20550	COG0513	Belongs to the DEAD box helicase family
GPY29_RS20580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY29_RS20585	COG2207	Transcriptional regulator
GPY29_RS20615	COG2354	Protein conserved in bacteria
GPY29_RS20620	COG0418	dihydroorotase activity
GPY29_RS20630	COG0401	homolog of Blt101
GPY29_RS20640	COG0633	Ferredoxin
GPY29_RS20640	COG3217	Mosc domain protein beta barrel domain protein
GPY29_RS20640	COG0633	Ferredoxin
GPY29_RS20640	COG3217	Mosc domain protein beta barrel domain protein
GPY29_RS20645	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GPY29_RS20650	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPY29_RS20690	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GPY29_RS20695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY29_RS20705	COG0848	biopolymer transport protein
GPY29_RS20710	COG0811	peptide transport
GPY29_RS20715	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GPY29_RS20725	COG3721	Heme iron utilization protein
GPY29_RS20730	COG0748	coenzyme F420 binding
GPY29_RS20740	COG0784	Response regulator, receiver
GPY29_RS20740	COG0835	chemotaxis
GPY29_RS20750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY29_RS20760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPY29_RS20760	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GPY29_RS20785	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GPY29_RS20790	COG0783	Belongs to the Dps family
GPY29_RS20800	COG0583	DNA-binding transcription factor activity
GPY29_RS20815	COG4934	collagen metabolic process
GPY29_RS20825	COG0366	Alpha amylase catalytic
GPY29_RS20845	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPY29_RS20850	COG0589	response to stress
GPY29_RS20855	COG0488	(ABC) transporter
GPY29_RS20860	COG1505	serine-type exopeptidase activity
GPY29_RS20870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY29_RS20880	COG2067	long-chain fatty acid transport protein
GPY29_RS20890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY29_RS20900	COG2203	Gaf domain
GPY29_RS20900	COG2199	diguanylate cyclase activity
GPY29_RS20920	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY29_RS20945	COG3383	formate dehydrogenase (NAD+) activity
GPY29_RS20960	COG0842	Transport permease protein
GPY29_RS20965	COG1131	(ABC) transporter
GPY29_RS20980	COG2706	6-phosphogluconolactonase activity
GPY29_RS20990	COG1881	PFAM PEBP family protein
GPY29_RS21000	COG0798	PFAM Bile acid sodium symporter
GPY29_RS21020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY29_RS21025	COG2213	PTS system mannitol-specific
GPY29_RS21030	COG1063	alcohol dehydrogenase
GPY29_RS21040	COG1072	(Pantothenic acid kinase))
GPY29_RS21045	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPY29_RS21065	COG0814	amino acid
GPY29_RS21105	COG0739	heme binding
GPY29_RS21110	COG5001	Diguanylate cyclase
GPY29_RS21115	COG0583	DNA-binding transcription factor activity
GPY29_RS21120	COG2814	Major facilitator Superfamily
GPY29_RS21145	COG0697	spore germination
GPY29_RS21175	COG2207	Transcriptional regulator
GPY29_RS21180	COG1280	lysine exporter protein (LysE YggA)
GPY29_RS21190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY29_RS21195	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GPY29_RS21205	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GPY29_RS21230	COG1612	heme a metabolic process
GPY29_RS21235	COG0109	protoheme IX farnesyltransferase activity
GPY29_RS21240	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY29_RS21275	COG1278	Cold shock
GPY29_RS21280	COG3036	rescue of stalled ribosome
GPY29_RS21295	COG2199	diguanylate cyclase activity
GPY29_RS21315	COG1136	(ABC) transporter
GPY29_RS21315	COG0577	efflux transmembrane transporter activity
GPY29_RS21325	COG0840	transmembrane signaling receptor activity
GPY29_RS21330	COG0783	Belongs to the Dps family
GPY29_RS21340	COG2133	pyrroloquinoline quinone binding
GPY29_RS21345	COG1454	alcohol dehydrogenase
GPY29_RS21350	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GPY29_RS21390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY29_RS21395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY29_RS21400	COG3186	Phenylalanine-4-hydroxylase
GPY29_RS21405	COG2154	pterin-4-alpha-carbinolamine dehydratase
GPY29_RS21430	COG3530	Putative quorum-sensing-regulated virulence factor
GPY29_RS21435	COG0513	Belongs to the DEAD box helicase family
GPY29_RS21440	COG4628	conserved protein (DUF2132)
GPY29_RS21445	COG0133	tryptophan synthase activity
GPY29_RS21455	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GPY29_RS21465	COG0523	cobalamin synthesis protein
GPY29_RS21470	COG0513	Belongs to the DEAD box helicase family
GPY29_RS21490	COG2200	EAL domain
GPY29_RS21495	COG1119	ATPase activity
GPY29_RS21500	COG0840	transmembrane signaling receptor activity
GPY29_RS21520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY29_RS21535	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GPY29_RS21540	COG0513	Belongs to the DEAD box helicase family
GPY29_RS21545	COG5001	Diguanylate cyclase
GPY29_RS21555	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPY29_RS21570	COG5413	integral membrane protein
GPY29_RS21580	COG1024	Enoyl-CoA hydratase
GPY29_RS21585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GPY29_RS21590	COG1960	acyl-CoA dehydrogenase activity
GPY29_RS21600	COG0183	Belongs to the thiolase family
GPY29_RS21620	COG1024	Enoyl-CoA hydratase
GPY29_RS21630	COG1028	Short-chain dehydrogenase reductase Sdr
GPY29_RS21635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GPY29_RS21640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPY29_RS21645	COG1845	cytochrome c oxidase, subunit III
GPY29_RS21650	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GPY29_RS21655	COG0109	protoheme IX farnesyltransferase activity
GPY29_RS21670	COG1902	pentaerythritol trinitrate reductase activity
GPY29_RS21680	COG1126	abc transporter atp-binding protein
GPY29_RS21685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY29_RS21690	COG4215	(ABC) transporter
GPY29_RS21695	COG4160	amino acid transport
GPY29_RS21710	COG0625	glutathione transferase activity
GPY29_RS21745	COG0443	Heat shock 70 kDa protein
GPY29_RS21750	COG2847	Copper chaperone PCu(A)C
GPY29_RS21775	COG4607	ABC-type enterochelin transport system periplasmic component
GPY29_RS21780	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY29_RS21785	COG4605	iron ion homeostasis
GPY29_RS21790	COG4604	ABC transporter, ATP-binding protein
GPY29_RS21795	COG0789	Transcriptional regulator
GPY29_RS21810	COG1629	transport
GPY29_RS21810	COG4771	TonB-dependent receptor
GPY29_RS21845	COG1289	transmembrane transporter activity
GPY29_RS21850	COG0210	DNA helicase
GPY29_RS21855	COG1803	Methylglyoxal synthase
GPY29_RS21860	COG1879	ABC-type sugar transport system periplasmic component
GPY29_RS21865	COG2198	Histidine kinase
GPY29_RS21865	COG2205	protein histidine kinase activity
GPY29_RS21865	COG0784	Response regulator, receiver
GPY29_RS21880	COG0745	RESPONSE REGULATOR receiver
GPY29_RS21885	COG3119	arylsulfatase activity
GPY29_RS21890	COG3119	arylsulfatase activity
GPY29_RS21905	COG3119	arylsulfatase activity
GPY29_RS21910	COG0641	radical SAM
GPY29_RS21915	COG0714	Associated with various cellular activities
GPY29_RS21945	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY29_RS21950	COG0583	DNA-binding transcription factor activity
GPY29_RS21955	COG1597	lipid kinase activity
GPY29_RS21960	COG3111	PFAM Bacterial OB fold (BOF) protein
GPY29_RS21980	COG0641	radical SAM
GPY29_RS22010	COG0501	Belongs to the peptidase M48B family
GPY29_RS22015	COG1704	LemA family
GPY29_RS22020	COG3069	C4-dicarboxylate transmembrane transporter activity
GPY29_RS22030	COG0456	acetyltransferase
GPY29_RS22030	COG1214	PFAM Peptidase M22, glycoprotease
GPY29_RS22050	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPY29_RS22055	COG1943	Transposase
GPY29_RS22075	COG2207	Transcriptional regulator
GPY29_RS22100	COG4964	Belongs to the GSP D family
GPY29_RS22180	COG3300	MHYT domain
GPY29_RS22180	COG5001	Diguanylate cyclase
GPY29_RS22185	COG2197	response regulator
GPY29_RS22190	COG3706	GGDEF domain
GPY29_RS22200	COG2197	response regulator
GPY29_RS22225	COG0835	chemotaxis
GPY29_RS22225	COG0784	Response regulator, receiver
GPY29_RS22245	COG2962	Rard protein
GPY29_RS22260	COG0671	phosphoesterase, PA-phosphatase related
GPY29_RS22275	COG2076	Multidrug Resistance protein
GPY29_RS22305	COG0471	metal ion transport
GPY29_RS22310	COG3290	protein histidine kinase activity
GPY29_RS22315	COG4565	transcriptional regulatory protein
GPY29_RS22325	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GPY29_RS22325	COG0069	glutamate synthase activity
GPY29_RS22335	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GPY29_RS22360	COG1902	pentaerythritol trinitrate reductase activity
GPY29_RS22365	COG0346	lactoylglutathione lyase activity
GPY29_RS22385	COG2239	Acts as a magnesium transporter
GPY29_RS22405	COG0242	peptide deformylase activity
GPY29_RS22450	COG2176	DNA-directed DNA polymerase activity
GPY29_RS22455	COG0583	DNA-binding transcription factor activity
GPY29_RS22460	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPY29_RS22465	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GPY29_RS22495	COG1733	regulation of RNA biosynthetic process
GPY29_RS22510	COG0583	DNA-binding transcription factor activity
GPY29_RS22520	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPY29_RS22520	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPY29_RS22525	COG0509	glycine decarboxylation via glycine cleavage system
GPY29_RS22530	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPY29_RS22570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY29_RS22570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY29_RS22570	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GPY29_RS22575	COG1105	Belongs to the carbohydrate kinase PfkB family
GPY29_RS22580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY29_RS22580	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY29_RS22585	COG1609	Transcriptional regulator
GPY29_RS22605	COG2200	EAL domain
GPY29_RS22605	COG2203	Gaf domain
GPY29_RS22605	COG2199	diguanylate cyclase activity
GPY29_RS22610	COG0765	amino acid transport
GPY29_RS22615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY29_RS22620	COG0765	amino acid transport
GPY29_RS22625	COG1126	abc transporter atp-binding protein
GPY29_RS22630	COG0469	pyruvate kinase activity
GPY29_RS22635	COG2271	Major facilitator Superfamily
GPY29_RS22640	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY29_RS22660	COG1979	alcohol dehydrogenase
GPY29_RS22665	COG2207	Transcriptional regulator
GPY29_RS22680	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPY29_RS22685	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GPY29_RS22690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY29_RS22710	COG3437	response regulator, receiver
GPY29_RS22710	COG0784	Response regulator, receiver
GPY29_RS22720	COG0546	phosphoglycolate phosphatase activity
GPY29_RS22725	COG0840	transmembrane signaling receptor activity
GPY29_RS22735	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GPY29_RS22740	COG0513	Belongs to the DEAD box helicase family
GPY29_RS22745	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GPY29_RS22760	COG3038	cytochrome b561
GPY29_RS22765	COG2353	YceI-like domain
GPY29_RS22770	COG2116	formate transmembrane transporter activity
GPY29_RS22775	COG0583	DNA-binding transcription factor activity
GPY29_RS22785	COG3593	DNA synthesis involved in DNA repair
GPY29_RS22790	COG0737	Belongs to the 5'-nucleotidase family
GPY29_RS22795	COG0861	Integral membrane protein TerC family
GPY29_RS22810	COG2267	carboxylic ester hydrolase activity
GPY29_RS22815	COG2067	long-chain fatty acid transport protein
GPY29_RS22830	COG2050	protein possibly involved in aromatic compounds catabolism
GPY29_RS22840	COG4533	DNA binding
GPY29_RS22865	COG0484	heat shock protein binding
GPY29_RS22875	COG3300	MHYT domain
GPY29_RS22875	COG5001	Diguanylate cyclase
GPY29_RS22880	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPY29_RS22890	COG4181	ATPase activity
GPY29_RS22895	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GPY29_RS22905	COG1984	allophanate hydrolase subunit 2
GPY29_RS22910	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GPY29_RS22915	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GPY29_RS22920	COG5001	Diguanylate cyclase
GPY29_RS22920	COG5002	protein histidine kinase activity
GPY29_RS22920	COG3447	MASE1 domain protein
GPY29_RS22925	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPY29_RS22935	COG4771	TonB-dependent receptor
GPY29_RS22935	COG1629	transport
GPY29_RS22940	COG0583	DNA-binding transcription factor activity
GPY29_RS22945	COG1042	CoA-binding domain protein
GPY29_RS22945	COG0045	succinate-CoA ligase (ADP-forming) activity
GPY29_RS22945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY29_RS22955	COG1181	Belongs to the D-alanine--D-alanine ligase family
GPY29_RS22965	COG0023	Translation Initiation Factor
GPY29_RS23065	COG0589	response to stress
GPY29_RS23070	COG3140	Belongs to the UPF0181 family
GPY29_RS23095	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GPY29_RS23100	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GPY29_RS23115	COG0745	RESPONSE REGULATOR receiver
GPY29_RS23115	COG3706	GGDEF domain
GPY29_RS23125	COG2203	Gaf domain
GPY29_RS23125	COG4251	negative regulation of phosphorylation
GPY29_RS23125	COG3706	GGDEF domain
GPY29_RS23125	COG5001	Diguanylate cyclase
GPY29_RS23135	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GPY29_RS23140	COG4149	molybdate abc transporter
GPY29_RS23145	COG0725	ABC transporter, periplasmic molybdate-binding protein
GPY29_RS23150	COG1492	cobalamin metabolic process
GPY29_RS23155	COG3111	PFAM Bacterial OB fold (BOF) protein
GPY29_RS23165	COG0189	ligase activity
GPY29_RS23165	COG4067	protein conserved in archaea
GPY29_RS23185	COG0534	Mate efflux family protein
GPY29_RS23190	COG0602	queuosine metabolic process
GPY29_RS23195	COG1328	CTP reductase activity
GPY29_RS23210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY29_RS23240	COG0243	molybdopterin cofactor binding
GPY29_RS23250	COG0583	DNA-binding transcription factor activity
GPY29_RS23255	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPY29_RS23265	COG2197	response regulator
GPY29_RS23270	COG3851	Histidine kinase
GPY29_RS23275	COG2271	Major facilitator Superfamily
GPY29_RS23300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY29_RS23305	COG3118	belongs to the thioredoxin family
GPY29_RS23310	COG2814	Major facilitator Superfamily
GPY29_RS23320	COG0534	Mate efflux family protein
GPY29_RS23350	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPY29_RS23370	COG2116	formate transmembrane transporter activity
GPY29_RS23375	COG2146	nitrite reductase [NAD(P)H] activity
GPY29_RS23380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPY29_RS23385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY29_RS23425	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPY29_RS23425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY29_RS23470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY29_RS23485	COG0277	FAD linked oxidase domain protein
GPY29_RS23490	COG0583	DNA-binding transcription factor activity
GPY29_RS23510	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GPY29_RS23525	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GPY29_RS23540	COG1288	antiporter activity
GPY29_RS23550	COG2814	Major facilitator Superfamily
GPY29_RS23560	COG3040	lipid binding
GPY29_RS23585	COG0420	3'-5' exonuclease activity
GPY29_RS23600	COG3501	Rhs element vgr protein
GPY29_RS23655	COG0631	protein serine/threonine phosphatase activity
GPY29_RS23690	COG0515	serine threonine protein kinase
GPY29_RS23690	COG2815	serine threonine protein kinase
GPY29_RS23750	COG1116	anion transmembrane transporter activity
GPY29_RS23755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GPY29_RS23760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GPY29_RS23760	COG1116	anion transmembrane transporter activity
GPY29_RS23770	COG3707	response regulator
GPY29_RS23790	COG1648	precorrin-2 dehydrogenase activity
GPY29_RS23790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPY29_RS23795	COG0243	molybdopterin cofactor binding
GPY29_RS23805	COG0456	acetyltransferase
GPY29_RS23810	COG0814	amino acid
GPY29_RS23820	COG3706	GGDEF domain
GPY29_RS23820	COG0745	RESPONSE REGULATOR receiver
GPY29_RS23840	COG1785	Belongs to the alkaline phosphatase family
GPY29_RS23855	COG0745	RESPONSE REGULATOR receiver
GPY29_RS23870	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GPY29_RS23885	COG1609	Transcriptional regulator
GPY29_RS23890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY29_RS23895	COG1879	ABC-type sugar transport system periplasmic component
GPY29_RS23900	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPY29_RS23905	COG1129	ABC transporter
GPY29_RS23910	COG1869	D-ribose catabolic process
GPY29_RS23915	COG5001	Diguanylate cyclase
GPY29_RS23920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPY29_RS23980	COG2205	protein histidine kinase activity
GPY29_RS23980	COG0784	Response regulator, receiver
GPY29_RS24000	COG3300	MHYT domain
GPY29_RS24000	COG5001	Diguanylate cyclase
GPY29_RS24010	COG0330	HflC and HflK could
GPY29_RS24025	COG4175	Glycine betaine
GPY29_RS24025	COG0517	IMP dehydrogenase activity
GPY29_RS24030	COG4176	ABC-type proline glycine betaine transport system permease component
GPY29_RS24045	COG1012	belongs to the aldehyde dehydrogenase family
GPY29_RS24050	COG1309	transcriptional regulator
GPY29_RS24055	COG3706	GGDEF domain
GPY29_RS24080	COG1024	Enoyl-CoA hydratase
GPY29_RS24085	COG1960	acyl-CoA dehydrogenase activity
GPY29_RS24095	COG0183	Belongs to the thiolase family
GPY29_RS24105	COG1960	acyl-CoA dehydrogenase activity
GPY29_RS24110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GPY29_RS24115	COG1024	Enoyl-CoA hydratase
GPY29_RS24130	COG3850	Histidine kinase
GPY29_RS24130	COG3437	response regulator, receiver
GPY29_RS24130	COG4999	Histidine kinase
GPY29_RS24130	COG2205	protein histidine kinase activity
GPY29_RS24145	COG0110	maltose O-acetyltransferase activity
GPY29_RS24150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY29_RS24155	COG1271	oxidase subunit
GPY29_RS24160	COG1294	oxidase, subunit
GPY29_RS24175	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPY29_RS24180	COG0789	Transcriptional regulator
GPY29_RS24190	COG3474	cytochrome
GPY29_RS24260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY29_RS24265	COG0516	GMP reductase activity
GPY29_RS24270	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GPY29_RS24270	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPY29_RS24285	COG4989	oxidoreductase activity
GPY29_RS24300	COG0038	chloride channel
GPY29_RS24310	COG1914	H( )-stimulated, divalent metal cation uptake system
GPY29_RS24315	COG0302	gtp cyclohydrolase
GPY29_RS24325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY29_RS24345	COG2897	thiosulfate sulfurtransferase activity
GPY29_RS24370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPY29_RS24375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPY29_RS24380	COG0840	transmembrane signaling receptor activity
GPY29_RS24390	COG2814	Major facilitator Superfamily
GPY29_RS24395	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY29_RS24405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY29_RS24415	COG0840	transmembrane signaling receptor activity
GPY29_RS24435	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY29_RS24450	COG2197	response regulator
GPY29_RS24455	COG3850	Histidine kinase
GPY29_RS24460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPY29_RS24470	COG0243	molybdopterin cofactor binding
GPY29_RS24480	COG3005	denitrification pathway
GPY29_RS24500	COG0183	Belongs to the thiolase family
GPY29_RS24520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY29_RS24525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY29_RS24550	COG1522	sequence-specific DNA binding
GPY29_RS24570	COG1566	PFAM secretion protein HlyD family protein
GPY29_RS24580	COG0784	Response regulator, receiver
GPY29_RS24580	COG2205	protein histidine kinase activity
GPY29_RS24585	COG1879	ABC-type sugar transport system periplasmic component
GPY29_RS24590	COG2827	Endonuclease containing a URI domain
GPY29_RS24595	COG3132	Protein of unknown function, DUF480
GPY29_RS24610	COG2926	Belongs to the UPF0265 family
GPY29_RS24615	COG0534	Mate efflux family protein
GPY29_RS24620	COG0673	inositol 2-dehydrogenase activity
GPY29_RS24625	COG0784	Response regulator, receiver
GPY29_RS24625	COG2205	protein histidine kinase activity
GPY29_RS24625	COG5002	protein histidine kinase activity
GPY29_RS24650	COG1522	sequence-specific DNA binding
GPY29_RS24660	COG0531	amino acid
GPY29_RS24675	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GPY29_RS24680	COG2239	Acts as a magnesium transporter
GPY29_RS24690	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GPY29_RS24695	COG0402	S-adenosylhomocysteine deaminase activity
GPY29_RS24705	COG1418	mRNA catabolic process
GPY29_RS24720	COG2814	Major facilitator Superfamily
GPY29_RS24730	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY29_RS24750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY29_RS24770	COG4221	oxidoreductase activity
GPY29_RS24775	COG0745	RESPONSE REGULATOR receiver
GPY29_RS24780	COG2205	protein histidine kinase activity
GPY29_RS24790	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPY29_RS24795	COG2194	sulfuric ester hydrolase activity
GPY29_RS24800	COG0673	inositol 2-dehydrogenase activity
GPY29_RS24810	COG2814	Major facilitator Superfamily
GPY29_RS24825	COG1846	Transcriptional regulator
GPY29_RS24835	COG4667	esterase of the alpha-beta hydrolase superfamily
GPY29_RS24840	COG1741	Belongs to the pirin family
GPY29_RS24845	COG1278	Cold shock
GPY29_RS24860	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPY29_RS24865	COG0678	peroxiredoxin activity
GPY29_RS24865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY29_RS24885	COG1686	Belongs to the peptidase S11 family
GPY29_RS24895	COG0625	glutathione transferase activity
GPY29_RS24905	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPY29_RS24920	COG1028	Short-chain dehydrogenase reductase Sdr
GPY29_RS24940	COG3746	phosphate-selective porin O and P
GPY29_RS24950	COG3246	L-lysine catabolic process to acetate
GPY29_RS24965	COG0183	Belongs to the thiolase family
GPY29_RS25005	COG3328	transposase activity
GPY29_RS25055	COG0804	urea catabolic process
GPY29_RS25075	COG0747	negative chemotaxis
GPY29_RS25085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY29_RS25100	COG2207	Transcriptional regulator
GPY29_RS25120	COG2916	Histone family protein nucleoid-structuring protein H-NS
GPY29_RS25205	COG4790	Type iii secretion
GPY29_RS25215	COG3710	Transcriptional regulator
GPY29_RS25245	COG4792	protein secretion
GPY29_RS25250	COG4789	Type iii secretion
GPY29_RS25335	COG2801	Transposase and inactivated derivatives
GPY29_RS25360	COG2202	Pas domain
GPY29_RS25360	COG2200	EAL domain
GPY29_RS25360	COG2199	diguanylate cyclase activity