locus-tag	class	description
GPY17_RS00015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY17_RS00035	COG0277	FAD linked oxidase domain protein
GPY17_RS00040	COG0583	DNA-binding transcription factor activity
GPY17_RS00060	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GPY17_RS00075	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GPY17_RS00090	COG1288	antiporter activity
GPY17_RS00100	COG2814	Major facilitator Superfamily
GPY17_RS00110	COG3040	lipid binding
GPY17_RS00130	COG0419	ATPase involved in DNA repair
GPY17_RS00135	COG0420	3'-5' exonuclease activity
GPY17_RS00150	COG3501	Rhs element vgr protein
GPY17_RS00205	COG0631	protein serine/threonine phosphatase activity
GPY17_RS00240	COG0515	serine threonine protein kinase
GPY17_RS00240	COG2815	serine threonine protein kinase
GPY17_RS00295	COG2146	nitrite reductase [NAD(P)H] activity
GPY17_RS00295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPY17_RS00300	COG1116	anion transmembrane transporter activity
GPY17_RS00305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GPY17_RS00310	COG1116	anion transmembrane transporter activity
GPY17_RS00310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GPY17_RS00320	COG3707	response regulator
GPY17_RS00345	COG0243	molybdopterin cofactor binding
GPY17_RS00350	COG0456	acetyltransferase
GPY17_RS00355	COG0814	amino acid
GPY17_RS00365	COG0745	RESPONSE REGULATOR receiver
GPY17_RS00365	COG3706	GGDEF domain
GPY17_RS00385	COG1785	Belongs to the alkaline phosphatase family
GPY17_RS00400	COG0745	RESPONSE REGULATOR receiver
GPY17_RS00415	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GPY17_RS00430	COG1609	Transcriptional regulator
GPY17_RS00435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY17_RS00440	COG1879	ABC-type sugar transport system periplasmic component
GPY17_RS00445	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPY17_RS00450	COG1129	ABC transporter
GPY17_RS00455	COG1869	D-ribose catabolic process
GPY17_RS00460	COG5001	Diguanylate cyclase
GPY17_RS00465	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPY17_RS00580	COG0784	Response regulator, receiver
GPY17_RS00580	COG2205	protein histidine kinase activity
GPY17_RS00600	COG5001	Diguanylate cyclase
GPY17_RS00600	COG3300	MHYT domain
GPY17_RS00610	COG0330	HflC and HflK could
GPY17_RS00625	COG4175	Glycine betaine
GPY17_RS00625	COG0517	IMP dehydrogenase activity
GPY17_RS00630	COG4176	ABC-type proline glycine betaine transport system permease component
GPY17_RS00645	COG1012	belongs to the aldehyde dehydrogenase family
GPY17_RS00650	COG1309	transcriptional regulator
GPY17_RS00655	COG3706	GGDEF domain
GPY17_RS00665	COG1028	Short-chain dehydrogenase reductase Sdr
GPY17_RS00680	COG1024	Enoyl-CoA hydratase
GPY17_RS00685	COG1960	acyl-CoA dehydrogenase activity
GPY17_RS00695	COG0183	Belongs to the thiolase family
GPY17_RS00705	COG1960	acyl-CoA dehydrogenase activity
GPY17_RS00710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GPY17_RS00715	COG1024	Enoyl-CoA hydratase
GPY17_RS00730	COG2205	protein histidine kinase activity
GPY17_RS00730	COG3850	Histidine kinase
GPY17_RS00730	COG4999	Histidine kinase
GPY17_RS00730	COG3437	response regulator, receiver
GPY17_RS00745	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GPY17_RS00745	COG3264	Mechanosensitive ion channel
GPY17_RS00755	COG0110	maltose O-acetyltransferase activity
GPY17_RS00760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY17_RS00765	COG1271	oxidase subunit
GPY17_RS00770	COG1294	oxidase, subunit
GPY17_RS00780	COG0384	phenazine biosynthesis protein PhzF
GPY17_RS00785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPY17_RS00790	COG0789	Transcriptional regulator
GPY17_RS00800	COG3474	cytochrome
GPY17_RS00865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY17_RS00870	COG0516	GMP reductase activity
GPY17_RS00875	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPY17_RS00875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GPY17_RS00890	COG4989	oxidoreductase activity
GPY17_RS00915	COG1914	H( )-stimulated, divalent metal cation uptake system
GPY17_RS00920	COG0302	gtp cyclohydrolase
GPY17_RS00930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY17_RS00950	COG2897	thiosulfate sulfurtransferase activity
GPY17_RS00975	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPY17_RS00980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPY17_RS00985	COG0840	transmembrane signaling receptor activity
GPY17_RS00995	COG2814	Major facilitator Superfamily
GPY17_RS01000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY17_RS01010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY17_RS01020	COG0840	transmembrane signaling receptor activity
GPY17_RS01040	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY17_RS01055	COG2197	response regulator
GPY17_RS01060	COG3850	Histidine kinase
GPY17_RS01065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPY17_RS01075	COG0243	molybdopterin cofactor binding
GPY17_RS01085	COG3005	denitrification pathway
GPY17_RS01105	COG0183	Belongs to the thiolase family
GPY17_RS01115	COG1280	lysine exporter protein (LysE YggA)
GPY17_RS01125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY17_RS01130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY17_RS01155	COG1522	sequence-specific DNA binding
GPY17_RS01175	COG1566	PFAM secretion protein HlyD family protein
GPY17_RS01185	COG2205	protein histidine kinase activity
GPY17_RS01185	COG0784	Response regulator, receiver
GPY17_RS01190	COG1879	ABC-type sugar transport system periplasmic component
GPY17_RS01195	COG2827	Endonuclease containing a URI domain
GPY17_RS01200	COG3132	Protein of unknown function, DUF480
GPY17_RS01215	COG2926	Belongs to the UPF0265 family
GPY17_RS01220	COG0534	Mate efflux family protein
GPY17_RS01225	COG0673	inositol 2-dehydrogenase activity
GPY17_RS01230	COG2205	protein histidine kinase activity
GPY17_RS01230	COG5002	protein histidine kinase activity
GPY17_RS01230	COG0784	Response regulator, receiver
GPY17_RS01255	COG1522	sequence-specific DNA binding
GPY17_RS01265	COG0531	amino acid
GPY17_RS01280	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GPY17_RS01285	COG2239	Acts as a magnesium transporter
GPY17_RS01295	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GPY17_RS01300	COG0402	S-adenosylhomocysteine deaminase activity
GPY17_RS01310	COG1418	mRNA catabolic process
GPY17_RS01325	COG2814	Major facilitator Superfamily
GPY17_RS01335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY17_RS01355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY17_RS01375	COG4221	oxidoreductase activity
GPY17_RS01380	COG0745	RESPONSE REGULATOR receiver
GPY17_RS01385	COG2205	protein histidine kinase activity
GPY17_RS01395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPY17_RS01400	COG2194	sulfuric ester hydrolase activity
GPY17_RS01405	COG0673	inositol 2-dehydrogenase activity
GPY17_RS01430	COG1846	Transcriptional regulator
GPY17_RS01440	COG4667	esterase of the alpha-beta hydrolase superfamily
GPY17_RS01445	COG1741	Belongs to the pirin family
GPY17_RS01450	COG1278	Cold shock
GPY17_RS01470	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPY17_RS01475	COG0678	peroxiredoxin activity
GPY17_RS01475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY17_RS01495	COG1686	Belongs to the peptidase S11 family
GPY17_RS01505	COG0625	glutathione transferase activity
GPY17_RS01515	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPY17_RS01520	COG0210	DNA helicase
GPY17_RS01540	COG1028	Short-chain dehydrogenase reductase Sdr
GPY17_RS01560	COG3746	phosphate-selective porin O and P
GPY17_RS01580	COG3833	ABC-type maltose transport systems, permease component
GPY17_RS01585	COG1175	transmembrane transport
GPY17_RS01595	COG3842	ATPase activity
GPY17_RS01660	COG1309	transcriptional regulator
GPY17_RS01665	COG2130	NADP-dependent
GPY17_RS01675	COG0753	catalase activity
GPY17_RS01680	COG2084	Dehydrogenase
GPY17_RS01685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY17_RS01690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY17_RS01700	COG2207	Transcriptional regulator
GPY17_RS01705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY17_RS01705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY17_RS01705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY17_RS01720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY17_RS01725	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GPY17_RS01735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY17_RS01740	COG0569	domain protein
GPY17_RS01750	COG5002	protein histidine kinase activity
GPY17_RS01755	COG1132	(ABC) transporter
GPY17_RS01760	COG4774	siderophore transport
GPY17_RS01765	COG1120	ATPase activity
GPY17_RS01770	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GPY17_RS01785	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GPY17_RS01785	COG2885	chlorophyll binding
GPY17_RS01820	COG2197	response regulator
GPY17_RS01840	COG0714	Associated with various cellular activities
GPY17_RS01860	COG2304	oxidoreductase activity
GPY17_RS01875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY17_RS01880	COG0581	inorganic phosphate transmembrane transporter activity
GPY17_RS01885	COG0573	inorganic phosphate transmembrane transporter activity
GPY17_RS01890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY17_RS01915	COG4771	TonB-dependent receptor
GPY17_RS01920	COG1770	oligopeptidase
GPY17_RS01925	COG0513	Belongs to the DEAD box helicase family
GPY17_RS01935	COG1388	LysM domain
GPY17_RS01935	COG1376	ErfK ybiS ycfS ynhG family protein
GPY17_RS01940	COG0415	Belongs to the DNA photolyase family
GPY17_RS01945	COG0789	Transcriptional regulator
GPY17_RS01950	COG3272	Protein of unknown function (DUF1722)
GPY17_RS01960	COG0813	purine-nucleoside phosphorylase activity
GPY17_RS01975	COG3706	GGDEF domain
GPY17_RS01985	COG1566	PFAM secretion protein HlyD family protein
GPY17_RS01990	COG4720	Psort location CytoplasmicMembrane, score
GPY17_RS01995	COG1122	ATPase activity
GPY17_RS02010	COG0348	domain, Protein
GPY17_RS02015	COG0437	4 iron, 4 sulfur cluster binding
GPY17_RS02020	COG1247	-acetyltransferase
GPY17_RS02050	COG1067	ATP-dependent peptidase activity
GPY17_RS02060	COG4172	Belongs to the ABC transporter superfamily
GPY17_RS02065	COG1505	serine-type exopeptidase activity
GPY17_RS02070	COG0583	DNA-binding transcription factor activity
GPY17_RS02075	COG1620	l-lactate permease
GPY17_RS02080	COG1304	FMN binding
GPY17_RS02090	COG0668	transmembrane transport
GPY17_RS02130	COG1063	alcohol dehydrogenase
GPY17_RS02135	COG0156	8-amino-7-oxononanoate synthase activity
GPY17_RS02145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY17_RS02165	COG0745	RESPONSE REGULATOR receiver
GPY17_RS02200	COG0346	lactoylglutathione lyase activity
GPY17_RS02220	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPY17_RS02260	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY17_RS02275	COG2204	response regulator
GPY17_RS02300	COG1987	bacterial-type flagellum assembly
GPY17_RS02325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY17_RS02335	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPY17_RS02340	COG1516	flagellar protein fliS
GPY17_RS02355	COG1580	Controls the rotational direction of flagella during chemotaxis
GPY17_RS02360	COG1191	sigma factor activity
GPY17_RS02365	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPY17_RS02370	COG1360	Flagellar Motor Protein
GPY17_RS02425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY17_RS02430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPY17_RS02440	COG0454	-acetyltransferase
GPY17_RS02450	COG2814	Major facilitator Superfamily
GPY17_RS02495	COG0628	permease
GPY17_RS02500	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPY17_RS02510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY17_RS02520	COG4628	conserved protein (DUF2132)
GPY17_RS02525	COG0583	DNA-binding transcription factor activity
GPY17_RS02550	COG1686	Belongs to the peptidase S11 family
GPY17_RS02570	COG3397	chitin binding
GPY17_RS02575	COG4667	esterase of the alpha-beta hydrolase superfamily
GPY17_RS02600	COG3206	protein involved in exopolysaccharide biosynthesis
GPY17_RS02600	COG0489	protein tyrosine kinase activity
GPY17_RS02615	COG0583	DNA-binding transcription factor activity
GPY17_RS02625	COG1301	dicarboxylic acid transport
GPY17_RS02630	COG3339	Conserved Protein
GPY17_RS02635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY17_RS02640	COG0700	Nucleoside recognition
GPY17_RS02645	COG3366	ferrous iron transmembrane transporter activity
GPY17_RS02665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPY17_RS02670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GPY17_RS02675	COG1640	4-alpha-glucanotransferase
GPY17_RS02680	COG0058	SHG alpha-glucan phosphorylase activity
GPY17_RS02695	COG2909	trisaccharide binding
GPY17_RS02710	COG1999	signal sequence binding
GPY17_RS02720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY17_RS02720	COG1263	PTS System
GPY17_RS02725	COG1162	GTPase activity
GPY17_RS02730	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GPY17_RS02740	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GPY17_RS02750	COG0531	amino acid
GPY17_RS02755	COG1982	Orn Lys Arg decarboxylase major
GPY17_RS02775	COG2356	endonuclease I
GPY17_RS02800	COG4580	involved in the transport of maltose and maltodextrins
GPY17_RS02815	COG2814	Major facilitator Superfamily
GPY17_RS02825	COG0739	heme binding
GPY17_RS02835	COG0612	Peptidase, M16
GPY17_RS02840	COG0840	transmembrane signaling receptor activity
GPY17_RS02845	COG1120	ATPase activity
GPY17_RS02850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY17_RS02855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY17_RS02860	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GPY17_RS02865	COG4772	TonB-dependent receptor
GPY17_RS02895	COG0019	diaminopimelate decarboxylase activity
GPY17_RS02900	COG1653	transport
GPY17_RS02910	COG0745	RESPONSE REGULATOR receiver
GPY17_RS02935	COG1172	Belongs to the binding-protein-dependent transport system permease family
GPY17_RS02940	COG1129	ABC transporter
GPY17_RS02945	COG1879	ABC-type sugar transport system periplasmic component
GPY17_RS02950	COG1069	ribulokinase activity
GPY17_RS02960	COG2160	L-arabinose isomerase activity
GPY17_RS02985	COG1764	response to oxidative stress
GPY17_RS02990	COG1846	Transcriptional regulator
GPY17_RS02995	COG0450	alkyl hydroperoxide reductase
GPY17_RS03000	COG3634	alkyl hydroperoxide reductase activity
GPY17_RS03030	COG1595	DNA-templated transcription, initiation
GPY17_RS03050	COG0583	DNA-binding transcription factor activity
GPY17_RS03055	COG1486	melibiose metabolic process
GPY17_RS03070	COG2258	MOSC domain
GPY17_RS03075	COG0513	Belongs to the DEAD box helicase family
GPY17_RS03100	COG1132	(ABC) transporter
GPY17_RS03145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY17_RS03175	COG0259	pyridoxamine-phosphate oxidase activity
GPY17_RS03220	COG4166	transmembrane transport
GPY17_RS03240	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPY17_RS03245	COG1263	PTS System
GPY17_RS03245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY17_RS03250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPY17_RS03255	COG3340	Belongs to the peptidase S51 family
GPY17_RS03275	COG1444	tRNA N-acetyltransferase activity
GPY17_RS03300	COG4608	Belongs to the ABC transporter superfamily
GPY17_RS03305	COG0444	Belongs to the ABC transporter superfamily
GPY17_RS03315	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY17_RS03315	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
GPY17_RS03340	COG0217	transcriptional regulatory protein
GPY17_RS03345	COG0772	Belongs to the SEDS family
GPY17_RS03360	COG1136	(ABC) transporter
GPY17_RS03380	COG3275	phosphorelay sensor kinase activity
GPY17_RS03395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPY17_RS03430	COG0786	glutamate:sodium symporter activity
GPY17_RS03440	COG1131	(ABC) transporter
GPY17_RS03445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY17_RS03450	COG0786	glutamate:sodium symporter activity
GPY17_RS03465	COG0363	glucosamine-6-phosphate deaminase activity
GPY17_RS03490	COG2259	Doxx family
GPY17_RS03505	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GPY17_RS03510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPY17_RS03520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPY17_RS03560	COG3123	guanosine phosphorylase activity
GPY17_RS03570	COG5001	Diguanylate cyclase
GPY17_RS03580	COG0534	Mate efflux family protein
GPY17_RS03585	COG0564	pseudouridine synthase activity
GPY17_RS03600	COG0583	DNA-binding transcription factor activity
GPY17_RS03605	COG0561	phosphatase activity
GPY17_RS03615	COG2199	diguanylate cyclase activity
GPY17_RS03630	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GPY17_RS03635	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GPY17_RS03640	COG0583	DNA-binding transcription factor activity
GPY17_RS03655	COG1414	Transcriptional regulator
GPY17_RS03660	COG1028	Short-chain dehydrogenase reductase Sdr
GPY17_RS03670	COG1917	Cupin 2, conserved barrel domain protein
GPY17_RS03685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY17_RS03690	COG0800	Aldolase
GPY17_RS03710	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY17_RS03715	COG0823	Involved in the tonB-independent uptake of proteins
GPY17_RS03720	COG2375	cellular response to nickel ion
GPY17_RS03750	COG1357	PFAM Pentapeptide repeats (8 copies)
GPY17_RS03755	COG3047	cAMP biosynthetic process
GPY17_RS03785	COG3408	Glycogen debranching enzyme
GPY17_RS03785	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GPY17_RS03790	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GPY17_RS03800	COG0583	DNA-binding transcription factor activity
GPY17_RS03810	COG0583	DNA-binding transcription factor activity
GPY17_RS03825	COG0546	phosphoglycolate phosphatase activity
GPY17_RS03850	COG3835	regulator
GPY17_RS03855	COG2610	gluconate transmembrane transporter activity
GPY17_RS03860	COG1929	Belongs to the glycerate kinase type-1 family
GPY17_RS03865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY17_RS03885	COG0456	acetyltransferase
GPY17_RS03900	COG1028	Short-chain dehydrogenase reductase Sdr
GPY17_RS03910	COG3005	denitrification pathway
GPY17_RS03915	COG0243	molybdopterin cofactor binding
GPY17_RS03925	COG0352	thiamine-phosphate diphosphorylase activity
GPY17_RS03930	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GPY17_RS03935	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GPY17_RS03940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GPY17_RS03945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GPY17_RS03950	COG1116	anion transmembrane transporter activity
GPY17_RS03955	COG0351	phosphomethylpyrimidine kinase
GPY17_RS03965	COG0312	modulator of DNA gyrase
GPY17_RS03970	COG0312	modulator of DNA gyrase
GPY17_RS03975	COG1901	pseudouridine methyltransferase
GPY17_RS04035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY17_RS04045	COG0584	glycerophosphoryl diester phosphodiesterase
GPY17_RS04055	COG0745	RESPONSE REGULATOR receiver
GPY17_RS04075	COG0811	peptide transport
GPY17_RS04080	COG0811	peptide transport
GPY17_RS04085	COG0848	biopolymer transport protein
GPY17_RS04125	COG0803	Belongs to the bacterial solute-binding protein 9 family
GPY17_RS04130	COG1121	(ABC) transporter
GPY17_RS04135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPY17_RS04150	COG1770	oligopeptidase
GPY17_RS04155	COG2814	Major facilitator Superfamily
GPY17_RS04160	COG0010	Belongs to the arginase family
GPY17_RS04165	COG1166	arginine decarboxylase activity
GPY17_RS04175	COG4067	protein conserved in archaea
GPY17_RS04175	COG0189	ligase activity
GPY17_RS04180	COG0189	ligase activity
GPY17_RS04185	COG0583	DNA-binding transcription factor activity
GPY17_RS04230	COG3706	GGDEF domain
GPY17_RS04235	COG1114	Component of the transport system for branched-chain amino acids
GPY17_RS04260	COG0579	oxidoreductase
GPY17_RS04270	COG3033	Beta-eliminating lyase
GPY17_RS04290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY17_RS04300	COG3145	DNA-N1-methyladenine dioxygenase activity
GPY17_RS04305	COG3706	GGDEF domain
GPY17_RS04310	COG0840	transmembrane signaling receptor activity
GPY17_RS04325	COG3706	GGDEF domain
GPY17_RS04330	COG0415	Belongs to the DNA photolyase family
GPY17_RS04335	COG3046	protein related to deoxyribodipyrimidine photolyase
GPY17_RS04350	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY17_RS04350	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY17_RS04355	COG1765	OsmC-like protein
GPY17_RS04360	COG0110	maltose O-acetyltransferase activity
GPY17_RS04400	COG1011	Hydrolase
GPY17_RS04415	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GPY17_RS04430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY17_RS04435	COG1136	(ABC) transporter
GPY17_RS04435	COG0577	efflux transmembrane transporter activity
GPY17_RS04445	COG3240	lipase activity
GPY17_RS04480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GPY17_RS04495	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY17_RS04505	COG3842	ATPase activity
GPY17_RS04530	COG2990	Protein conserved in bacteria
GPY17_RS04540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY17_RS04545	COG2866	Carboxypeptidase
GPY17_RS04560	COG0583	DNA-binding transcription factor activity
GPY17_RS04585	COG1760	l-serine dehydratase
GPY17_RS04605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPY17_RS04615	COG0741	lytic transglycosylase activity
GPY17_RS04635	COG1815	bacterial-type flagellum-dependent cell motility
GPY17_RS04640	COG1558	bacterial-type flagellum-dependent cell motility
GPY17_RS04645	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPY17_RS04650	COG1749	Flagellar hook protein flgE
GPY17_RS04655	COG4787	bacterial-type flagellum-dependent cell motility
GPY17_RS04660	COG4786	Flagellar basal body rod
GPY17_RS04665	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GPY17_RS04670	COG1706	bacterial-type flagellum-dependent cell motility
GPY17_RS04680	COG4786	Flagellar basal body rod
GPY17_RS04680	COG1256	bacterial-type flagellum assembly
GPY17_RS04685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY17_RS04735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY17_RS04745	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPY17_RS04750	COG0459	protein refolding
GPY17_RS04765	COG1280	lysine exporter protein (LysE YggA)
GPY17_RS04785	COG1309	transcriptional regulator
GPY17_RS04795	COG0737	Belongs to the 5'-nucleotidase family
GPY17_RS04800	COG2070	2-Nitropropane dioxygenase
GPY17_RS04805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY17_RS04820	COG0346	lactoylglutathione lyase activity
GPY17_RS04825	COG1349	DNA-binding transcription factor activity
GPY17_RS04835	COG0753	catalase activity
GPY17_RS04845	COG1335	isochorismatase
GPY17_RS04855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPY17_RS04885	COG0583	DNA-binding transcription factor activity
GPY17_RS04900	COG3713	MltA-interacting MipA family protein
GPY17_RS04910	COG3015	lipoprotein NlpE involved in copper resistance
GPY17_RS04920	COG1342	Belongs to the UPF0251 family
GPY17_RS04945	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPY17_RS04955	COG4948	Mandelate Racemase Muconate Lactonizing
GPY17_RS04965	COG0583	DNA-binding transcription factor activity
GPY17_RS05015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPY17_RS05065	COG3842	ATPase activity
GPY17_RS05115	COG3706	GGDEF domain
GPY17_RS05135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY17_RS05150	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY17_RS05155	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPY17_RS05175	COG0574	Belongs to the PEP-utilizing enzyme family
GPY17_RS05175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPY17_RS05180	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GPY17_RS05185	COG0252	asparaginase activity
GPY17_RS05195	COG0583	DNA-binding transcription factor activity
GPY17_RS05210	COG3122	Protein conserved in bacteria
GPY17_RS05225	COG1028	Short-chain dehydrogenase reductase Sdr
GPY17_RS05235	COG1063	alcohol dehydrogenase
GPY17_RS05240	COG1902	pentaerythritol trinitrate reductase activity
GPY17_RS05255	COG0583	DNA-binding transcription factor activity
GPY17_RS05265	COG0513	Belongs to the DEAD box helicase family
GPY17_RS05310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY17_RS05315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY17_RS05315	COG2207	Transcriptional regulator
GPY17_RS05345	COG2354	Protein conserved in bacteria
GPY17_RS05350	COG0418	dihydroorotase activity
GPY17_RS05360	COG0401	homolog of Blt101
GPY17_RS05370	COG0633	Ferredoxin
GPY17_RS05370	COG3217	Mosc domain protein beta barrel domain protein
GPY17_RS05370	COG0633	Ferredoxin
GPY17_RS05370	COG3217	Mosc domain protein beta barrel domain protein
GPY17_RS05375	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GPY17_RS05380	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPY17_RS05420	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GPY17_RS05425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPY17_RS05435	COG0848	biopolymer transport protein
GPY17_RS05440	COG0811	peptide transport
GPY17_RS05445	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GPY17_RS05455	COG3721	Heme iron utilization protein
GPY17_RS05460	COG0748	coenzyme F420 binding
GPY17_RS05470	COG0835	chemotaxis
GPY17_RS05470	COG0784	Response regulator, receiver
GPY17_RS05480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY17_RS05550	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GPY17_RS05555	COG0783	Belongs to the Dps family
GPY17_RS05565	COG0583	DNA-binding transcription factor activity
GPY17_RS05580	COG4934	collagen metabolic process
GPY17_RS05590	COG0366	Alpha amylase catalytic
GPY17_RS05610	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPY17_RS05615	COG0589	response to stress
GPY17_RS05620	COG0488	(ABC) transporter
GPY17_RS05625	COG1505	serine-type exopeptidase activity
GPY17_RS05635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY17_RS05645	COG2067	long-chain fatty acid transport protein
GPY17_RS05655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY17_RS05665	COG2199	diguanylate cyclase activity
GPY17_RS05665	COG2203	Gaf domain
GPY17_RS05685	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY17_RS05710	COG3383	formate dehydrogenase (NAD+) activity
GPY17_RS05725	COG0842	Transport permease protein
GPY17_RS05730	COG1131	(ABC) transporter
GPY17_RS05745	COG2706	6-phosphogluconolactonase activity
GPY17_RS05755	COG1881	PFAM PEBP family protein
GPY17_RS05765	COG0798	PFAM Bile acid sodium symporter
GPY17_RS05785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY17_RS05790	COG2213	PTS system mannitol-specific
GPY17_RS05795	COG1063	alcohol dehydrogenase
GPY17_RS05805	COG1072	(Pantothenic acid kinase))
GPY17_RS05810	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GPY17_RS05830	COG0814	amino acid
GPY17_RS05870	COG0739	heme binding
GPY17_RS05875	COG5001	Diguanylate cyclase
GPY17_RS05880	COG0583	DNA-binding transcription factor activity
GPY17_RS05885	COG2814	Major facilitator Superfamily
GPY17_RS05910	COG0697	spore germination
GPY17_RS05945	COG1280	lysine exporter protein (LysE YggA)
GPY17_RS05955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY17_RS05960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GPY17_RS05965	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPY17_RS05970	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GPY17_RS05995	COG1612	heme a metabolic process
GPY17_RS06000	COG0109	protoheme IX farnesyltransferase activity
GPY17_RS06005	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY17_RS06040	COG1278	Cold shock
GPY17_RS06045	COG3036	rescue of stalled ribosome
GPY17_RS06060	COG2199	diguanylate cyclase activity
GPY17_RS06080	COG0577	efflux transmembrane transporter activity
GPY17_RS06080	COG1136	(ABC) transporter
GPY17_RS06090	COG0840	transmembrane signaling receptor activity
GPY17_RS06095	COG0783	Belongs to the Dps family
GPY17_RS06105	COG2133	pyrroloquinoline quinone binding
GPY17_RS06110	COG1454	alcohol dehydrogenase
GPY17_RS06115	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GPY17_RS06155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY17_RS06160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY17_RS06165	COG3186	Phenylalanine-4-hydroxylase
GPY17_RS06170	COG2154	pterin-4-alpha-carbinolamine dehydratase
GPY17_RS06195	COG3530	Putative quorum-sensing-regulated virulence factor
GPY17_RS06200	COG0513	Belongs to the DEAD box helicase family
GPY17_RS06205	COG4628	conserved protein (DUF2132)
GPY17_RS06210	COG0133	tryptophan synthase activity
GPY17_RS06220	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GPY17_RS06230	COG0523	cobalamin synthesis protein
GPY17_RS06235	COG0513	Belongs to the DEAD box helicase family
GPY17_RS06255	COG2200	EAL domain
GPY17_RS06260	COG1119	ATPase activity
GPY17_RS06265	COG0840	transmembrane signaling receptor activity
GPY17_RS06290	COG0641	radical SAM
GPY17_RS06310	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GPY17_RS06325	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GPY17_RS06330	COG0513	Belongs to the DEAD box helicase family
GPY17_RS06335	COG5001	Diguanylate cyclase
GPY17_RS06345	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPY17_RS06360	COG5413	integral membrane protein
GPY17_RS06370	COG1024	Enoyl-CoA hydratase
GPY17_RS06375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GPY17_RS06380	COG1960	acyl-CoA dehydrogenase activity
GPY17_RS06390	COG0183	Belongs to the thiolase family
GPY17_RS06410	COG1024	Enoyl-CoA hydratase
GPY17_RS06420	COG1028	Short-chain dehydrogenase reductase Sdr
GPY17_RS06425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GPY17_RS06430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPY17_RS06435	COG1845	cytochrome c oxidase, subunit III
GPY17_RS06440	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GPY17_RS06445	COG0109	protoheme IX farnesyltransferase activity
GPY17_RS06460	COG1902	pentaerythritol trinitrate reductase activity
GPY17_RS06490	COG1126	abc transporter atp-binding protein
GPY17_RS06495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY17_RS06500	COG4215	(ABC) transporter
GPY17_RS06505	COG4160	amino acid transport
GPY17_RS06520	COG0625	glutathione transferase activity
GPY17_RS06555	COG0443	Heat shock 70 kDa protein
GPY17_RS06560	COG2847	Copper chaperone PCu(A)C
GPY17_RS06585	COG4607	ABC-type enterochelin transport system periplasmic component
GPY17_RS06595	COG4605	iron ion homeostasis
GPY17_RS06600	COG4604	ABC transporter, ATP-binding protein
GPY17_RS06605	COG0789	Transcriptional regulator
GPY17_RS06620	COG4771	TonB-dependent receptor
GPY17_RS06620	COG1629	transport
GPY17_RS06655	COG1289	transmembrane transporter activity
GPY17_RS06660	COG0210	DNA helicase
GPY17_RS06665	COG1803	Methylglyoxal synthase
GPY17_RS06670	COG1879	ABC-type sugar transport system periplasmic component
GPY17_RS06675	COG2205	protein histidine kinase activity
GPY17_RS06675	COG2198	Histidine kinase
GPY17_RS06675	COG0784	Response regulator, receiver
GPY17_RS06690	COG0745	RESPONSE REGULATOR receiver
GPY17_RS06695	COG3119	arylsulfatase activity
GPY17_RS06700	COG3119	arylsulfatase activity
GPY17_RS06715	COG3119	arylsulfatase activity
GPY17_RS06720	COG0641	radical SAM
GPY17_RS06725	COG0714	Associated with various cellular activities
GPY17_RS06755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY17_RS06760	COG0583	DNA-binding transcription factor activity
GPY17_RS06765	COG1597	lipid kinase activity
GPY17_RS06770	COG3111	PFAM Bacterial OB fold (BOF) protein
GPY17_RS06790	COG0641	radical SAM
GPY17_RS06820	COG0501	Belongs to the peptidase M48B family
GPY17_RS06825	COG1704	LemA family
GPY17_RS06830	COG3069	C4-dicarboxylate transmembrane transporter activity
GPY17_RS06860	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPY17_RS06875	COG0641	radical SAM
GPY17_RS06910	COG2003	Belongs to the UPF0758 family
GPY17_RS06920	COG1609	Transcriptional regulator
GPY17_RS06925	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY17_RS06950	COG2084	Dehydrogenase
GPY17_RS06975	COG1454	alcohol dehydrogenase
GPY17_RS06980	COG0235	Class ii aldolase
GPY17_RS06985	COG4806	L-rhamnose isomerase
GPY17_RS06990	COG1070	Carbohydrate kinase
GPY17_RS06995	COG3254	rhamnose metabolic process
GPY17_RS07040	COG0840	transmembrane signaling receptor activity
GPY17_RS07040	COG5278	phosphoserine phosphatase activity
GPY17_RS07070	COG0840	transmembrane signaling receptor activity
GPY17_RS07075	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GPY17_RS07085	COG3710	Transcriptional regulator
GPY17_RS07135	COG2814	Major facilitator Superfamily
GPY17_RS07135	COG0477	Major facilitator Superfamily
GPY17_RS07145	COG1940	carbohydrate kinase activity
GPY17_RS07150	COG0737	Belongs to the 5'-nucleotidase family
GPY17_RS07185	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GPY17_RS07190	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GPY17_RS07195	COG0732	type I restriction modification DNA specificity domain
GPY17_RS07220	COG1401	restriction endodeoxyribonuclease activity
GPY17_RS07230	COG0582	viral genome integration into host DNA
GPY17_RS07250	COG2207	Transcriptional regulator
GPY17_RS07275	COG4964	Belongs to the GSP D family
GPY17_RS07335	COG0583	DNA-binding transcription factor activity
GPY17_RS07340	COG0583	DNA-binding transcription factor activity
GPY17_RS07355	COG5001	Diguanylate cyclase
GPY17_RS07355	COG3300	MHYT domain
GPY17_RS07360	COG2197	response regulator
GPY17_RS07365	COG3706	GGDEF domain
GPY17_RS07375	COG2197	response regulator
GPY17_RS07400	COG0784	Response regulator, receiver
GPY17_RS07400	COG0835	chemotaxis
GPY17_RS07420	COG2962	Rard protein
GPY17_RS07435	COG0671	phosphoesterase, PA-phosphatase related
GPY17_RS07450	COG2076	Multidrug Resistance protein
GPY17_RS07480	COG0471	metal ion transport
GPY17_RS07485	COG3290	protein histidine kinase activity
GPY17_RS07490	COG4565	transcriptional regulatory protein
GPY17_RS07500	COG0069	glutamate synthase activity
GPY17_RS07500	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GPY17_RS07510	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GPY17_RS07535	COG1902	pentaerythritol trinitrate reductase activity
GPY17_RS07540	COG0346	lactoylglutathione lyase activity
GPY17_RS07560	COG2239	Acts as a magnesium transporter
GPY17_RS07590	COG0242	peptide deformylase activity
GPY17_RS07635	COG2176	DNA-directed DNA polymerase activity
GPY17_RS07640	COG0583	DNA-binding transcription factor activity
GPY17_RS07645	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPY17_RS07650	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GPY17_RS07680	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPY17_RS07680	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPY17_RS07685	COG0509	glycine decarboxylation via glycine cleavage system
GPY17_RS07690	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPY17_RS07730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY17_RS07730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GPY17_RS07730	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GPY17_RS07735	COG1105	Belongs to the carbohydrate kinase PfkB family
GPY17_RS07740	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY17_RS07740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY17_RS07745	COG1609	Transcriptional regulator
GPY17_RS07765	COG2200	EAL domain
GPY17_RS07765	COG2199	diguanylate cyclase activity
GPY17_RS07765	COG2203	Gaf domain
GPY17_RS07770	COG0765	amino acid transport
GPY17_RS07775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY17_RS07780	COG0765	amino acid transport
GPY17_RS07785	COG1126	abc transporter atp-binding protein
GPY17_RS07790	COG0469	pyruvate kinase activity
GPY17_RS07795	COG2271	Major facilitator Superfamily
GPY17_RS07800	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY17_RS07820	COG1979	alcohol dehydrogenase
GPY17_RS07825	COG2207	Transcriptional regulator
GPY17_RS07840	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPY17_RS07845	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GPY17_RS07850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY17_RS07870	COG3437	response regulator, receiver
GPY17_RS07870	COG0784	Response regulator, receiver
GPY17_RS07880	COG0546	phosphoglycolate phosphatase activity
GPY17_RS07885	COG0840	transmembrane signaling receptor activity
GPY17_RS07895	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GPY17_RS07900	COG0513	Belongs to the DEAD box helicase family
GPY17_RS07905	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GPY17_RS07920	COG3038	cytochrome b561
GPY17_RS07925	COG2353	YceI-like domain
GPY17_RS07930	COG2116	formate transmembrane transporter activity
GPY17_RS07935	COG0583	DNA-binding transcription factor activity
GPY17_RS07945	COG3593	DNA synthesis involved in DNA repair
GPY17_RS07950	COG0737	Belongs to the 5'-nucleotidase family
GPY17_RS07955	COG0861	Integral membrane protein TerC family
GPY17_RS07970	COG2267	carboxylic ester hydrolase activity
GPY17_RS07975	COG2067	long-chain fatty acid transport protein
GPY17_RS07990	COG2050	protein possibly involved in aromatic compounds catabolism
GPY17_RS08000	COG4533	DNA binding
GPY17_RS08025	COG0484	heat shock protein binding
GPY17_RS08035	COG5001	Diguanylate cyclase
GPY17_RS08035	COG3300	MHYT domain
GPY17_RS08040	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPY17_RS08050	COG4181	ATPase activity
GPY17_RS08055	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GPY17_RS08065	COG1984	allophanate hydrolase subunit 2
GPY17_RS08070	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GPY17_RS08075	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GPY17_RS08080	COG5002	protein histidine kinase activity
GPY17_RS08080	COG5001	Diguanylate cyclase
GPY17_RS08080	COG3447	MASE1 domain protein
GPY17_RS08085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPY17_RS08095	COG1629	transport
GPY17_RS08095	COG4771	TonB-dependent receptor
GPY17_RS08100	COG0583	DNA-binding transcription factor activity
GPY17_RS08105	COG0045	succinate-CoA ligase (ADP-forming) activity
GPY17_RS08105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY17_RS08105	COG1042	CoA-binding domain protein
GPY17_RS08115	COG1181	Belongs to the D-alanine--D-alanine ligase family
GPY17_RS08125	COG0023	Translation Initiation Factor
GPY17_RS08175	COG4128	Pfam Zonular occludens toxin
GPY17_RS08215	COG0583	DNA-binding transcription factor activity
GPY17_RS08225	COG0589	response to stress
GPY17_RS08230	COG3140	Belongs to the UPF0181 family
GPY17_RS08255	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GPY17_RS08260	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GPY17_RS08275	COG3706	GGDEF domain
GPY17_RS08275	COG0745	RESPONSE REGULATOR receiver
GPY17_RS08285	COG3706	GGDEF domain
GPY17_RS08285	COG5001	Diguanylate cyclase
GPY17_RS08285	COG4251	negative regulation of phosphorylation
GPY17_RS08285	COG2203	Gaf domain
GPY17_RS08295	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GPY17_RS08300	COG4149	molybdate abc transporter
GPY17_RS08305	COG0725	ABC transporter, periplasmic molybdate-binding protein
GPY17_RS08310	COG1492	cobalamin metabolic process
GPY17_RS08325	COG0189	ligase activity
GPY17_RS08325	COG4067	protein conserved in archaea
GPY17_RS08345	COG0534	Mate efflux family protein
GPY17_RS08350	COG0602	queuosine metabolic process
GPY17_RS08355	COG1328	CTP reductase activity
GPY17_RS08370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY17_RS08400	COG0243	molybdopterin cofactor binding
GPY17_RS08410	COG0583	DNA-binding transcription factor activity
GPY17_RS08415	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPY17_RS08425	COG2197	response regulator
GPY17_RS08430	COG3851	Histidine kinase
GPY17_RS08435	COG2271	Major facilitator Superfamily
GPY17_RS08460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY17_RS08465	COG3118	belongs to the thioredoxin family
GPY17_RS08470	COG2814	Major facilitator Superfamily
GPY17_RS08480	COG0534	Mate efflux family protein
GPY17_RS08510	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPY17_RS08530	COG2116	formate transmembrane transporter activity
GPY17_RS08535	COG2146	nitrite reductase [NAD(P)H] activity
GPY17_RS08540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPY17_RS08545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY17_RS08585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY17_RS08585	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPY17_RS08625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPY17_RS08630	COG0019	diaminopimelate decarboxylase activity
GPY17_RS08640	COG1965	Belongs to the frataxin family
GPY17_RS08645	COG3072	Adenylate cyclase
GPY17_RS08650	COG0181	hydroxymethylbilane synthase activity
GPY17_RS08655	COG1587	Uroporphyrinogen-III synthase
GPY17_RS08660	COG2959	enzyme of heme biosynthesis
GPY17_RS08665	COG3071	HemY protein
GPY17_RS08720	COG0633	Ferredoxin
GPY17_RS08725	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GPY17_RS08740	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPY17_RS08745	COG3118	belongs to the thioredoxin family
GPY17_RS08750	COG0513	Belongs to the DEAD box helicase family
GPY17_RS08755	COG0248	Ppx GppA phosphatase
GPY17_RS08760	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPY17_RS08775	COG0514	ATP-dependent DNA helicase (RecQ)
GPY17_RS08780	COG2962	Rard protein
GPY17_RS08790	COG1280	lysine exporter protein (LysE YggA)
GPY17_RS08795	COG0405	Gamma-glutamyltransferase
GPY17_RS08805	COG0210	DNA helicase
GPY17_RS08815	COG3220	belongs to the UPF0276 family
GPY17_RS08845	COG0006	proline dipeptidase activity
GPY17_RS08845	COG0006	proline dipeptidase activity
GPY17_RS08855	COG2022	thiamine diphosphate biosynthetic process
GPY17_RS08860	COG2104	thiamine diphosphate biosynthetic process
GPY17_RS08865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GPY17_RS08870	COG0352	thiamine-phosphate diphosphorylase activity
GPY17_RS08875	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GPY17_RS08880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPY17_RS08885	COG3335	DDE superfamily endonuclease
GPY17_RS08935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY17_RS08940	COG1739	Uncharacterized protein family UPF0029
GPY17_RS08945	COG1024	Enoyl-CoA hydratase
GPY17_RS08945	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPY17_RS08950	COG0183	Belongs to the thiolase family
GPY17_RS08955	COG0604	alcohol dehydrogenase
GPY17_RS08970	COG0425	Belongs to the sulfur carrier protein TusA family
GPY17_RS08980	COG2119	membrane
GPY17_RS08985	COG0752	glycyl-tRNA synthetase alpha subunit
GPY17_RS08990	COG0751	glycine-tRNA ligase activity
GPY17_RS08995	COG0366	Alpha amylase catalytic
GPY17_RS09000	COG3977	Valine--pyruvate aminotransferase
GPY17_RS09005	COG0071	Belongs to the small heat shock protein (HSP20) family
GPY17_RS09025	COG0187	DNA topoisomerase II activity
GPY17_RS09030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPY17_RS09035	COG0592	DNA-directed DNA polymerase activity
GPY17_RS09040	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPY17_RS09065	COG1126	abc transporter atp-binding protein
GPY17_RS09075	COG0594	ribonuclease P activity
GPY17_RS09085	COG0706	membrane insertase activity
GPY17_RS09090	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPY17_RS09095	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY17_RS09100	COG0445	tRNA wobble uridine modification
GPY17_RS09105	COG0357	Ribosomal RNA small subunit methyltransferase G
GPY17_RS09110	COG1192	Involved in chromosome partitioning
GPY17_RS09115	COG1475	DNA binding
GPY17_RS09120	COG3312	ion transport
GPY17_RS09125	COG0356	it plays a direct role in the translocation of protons across the membrane
GPY17_RS09140	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPY17_RS09145	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPY17_RS09150	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPY17_RS09155	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPY17_RS09160	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GPY17_RS09165	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPY17_RS09170	COG0765	amino acid transport
GPY17_RS09175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY17_RS09180	COG2814	Major facilitator Superfamily
GPY17_RS09185	COG0583	DNA-binding transcription factor activity
GPY17_RS09195	COG0129	dihydroxy-acid dehydratase activity
GPY17_RS09200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GPY17_RS09205	COG3978	acetolactate synthase activity
GPY17_RS09215	COG0606	chelatase, subunit chli
GPY17_RS09225	COG0204	Acyl-transferase
GPY17_RS09230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY17_RS09235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPY17_RS09245	COG3084	Protein conserved in bacteria
GPY17_RS09255	COG4326	sporulation control protein
GPY17_RS09260	COG1272	protein, Hemolysin III
GPY17_RS09270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY17_RS09275	COG0569	domain protein
GPY17_RS09280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPY17_RS09280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPY17_RS09285	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPY17_RS09290	COG0242	peptide deformylase activity
GPY17_RS09300	COG0758	DNA mediated transformation
GPY17_RS09305	COG2922	Belongs to the Smg family
GPY17_RS09310	COG0551	DNA topoisomerase type I activity
GPY17_RS09315	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPY17_RS09320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPY17_RS09325	COG0009	L-threonylcarbamoyladenylate synthase
GPY17_RS09330	COG0408	coproporphyrinogen oxidase activity
GPY17_RS09335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPY17_RS09345	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPY17_RS09385	COG0583	DNA-binding transcription factor activity
GPY17_RS09390	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPY17_RS09395	COG2960	long-chain fatty acid transporting porin activity
GPY17_RS09405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY17_RS09410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY17_RS09475	COG4172	Belongs to the ABC transporter superfamily
GPY17_RS09480	COG0747	negative chemotaxis
GPY17_RS09490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY17_RS09530	COG1609	Transcriptional regulator
GPY17_RS09535	COG0583	DNA-binding transcription factor activity
GPY17_RS09545	COG2076	Multidrug Resistance protein
GPY17_RS09550	COG0129	dihydroxy-acid dehydratase activity
GPY17_RS09555	COG3265	gluconokinase activity
GPY17_RS09560	COG2610	gluconate transmembrane transporter activity
GPY17_RS09565	COG0800	Aldolase
GPY17_RS09570	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GPY17_RS09575	COG0583	DNA-binding transcription factor activity
GPY17_RS09580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY17_RS09585	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GPY17_RS09590	COG0339	signal peptide processing
GPY17_RS09595	COG1522	sequence-specific DNA binding
GPY17_RS09600	COG5002	protein histidine kinase activity
GPY17_RS09600	COG5001	Diguanylate cyclase
GPY17_RS09605	COG0742	ribosomal rna small subunit methyltransferase
GPY17_RS09615	COG0697	spore germination
GPY17_RS09620	COG0589	response to stress
GPY17_RS09625	COG1528	Iron-storage protein
GPY17_RS09635	COG2081	HI0933 family
GPY17_RS09640	COG2204	response regulator
GPY17_RS09645	COG2823	Periplasmic or secreted lipoprotein
GPY17_RS09665	COG1597	lipid kinase activity
GPY17_RS09695	COG0628	permease
GPY17_RS09710	COG1322	Protein conserved in bacteria
GPY17_RS09715	COG2226	methyltransferase
GPY17_RS09720	COG3165	ubiquinone biosynthetic process from chorismate
GPY17_RS09725	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GPY17_RS09730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPY17_RS09740	COG0805	protein transport
GPY17_RS09750	COG0084	hydrolase, TatD family'
GPY17_RS09775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY17_RS09775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY17_RS09785	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GPY17_RS09815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY17_RS09820	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GPY17_RS09830	COG2204	response regulator
GPY17_RS09835	COG3852	Histidine kinase
GPY17_RS09845	COG0174	glutamine synthetase
GPY17_RS09865	COG1295	ribonuclease BN
GPY17_RS09870	COG1490	D-aminoacyl-tRNA deacylase activity
GPY17_RS09875	COG0456	acetyltransferase
GPY17_RS09885	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GPY17_RS09890	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPY17_RS09895	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GPY17_RS09900	COG3031	protein transport across the cell outer membrane
GPY17_RS09910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY17_RS09915	COG1459	type II secretion system
GPY17_RS09920	COG2165	general secretion pathway protein
GPY17_RS09925	COG2165	general secretion pathway protein
GPY17_RS09930	COG2165	general secretion pathway protein
GPY17_RS09935	COG4795	General secretion pathway protein
GPY17_RS09940	COG3156	type II secretion system protein K
GPY17_RS09945	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPY17_RS09950	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GPY17_RS09960	COG1218	3'(2'),5'-bisphosphate nucleotidase
GPY17_RS09965	COG0494	nUDIX hydrolase
GPY17_RS09970	COG0316	Belongs to the HesB IscA family
GPY17_RS09970	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GPY17_RS09975	COG1040	competence protein
GPY17_RS09980	COG0596	Alpha beta hydrolase
GPY17_RS09990	COG2183	response to ionizing radiation
GPY17_RS10000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY17_RS10010	COG0745	RESPONSE REGULATOR receiver
GPY17_RS10015	COG2205	protein histidine kinase activity
GPY17_RS10020	COG2233	PERMEase
GPY17_RS10030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY17_RS10035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY17_RS10040	COG1758	RNA polymerase activity
GPY17_RS10045	COG0194	GDP metabolic process
GPY17_RS10060	COG0848	biopolymer transport protein
GPY17_RS10065	COG0811	peptide transport
GPY17_RS10090	COG4174	ABC transporter (Permease)
GPY17_RS10100	COG0747	negative chemotaxis
GPY17_RS10105	COG0444	Belongs to the ABC transporter superfamily
GPY17_RS10110	COG4608	Belongs to the ABC transporter superfamily
GPY17_RS10120	COG1561	YicC-like family, N-terminal region
GPY17_RS10125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GPY17_RS10130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPY17_RS10135	COG1560	Kdo2-lipid A biosynthetic process
GPY17_RS10140	COG1309	transcriptional regulator
GPY17_RS10145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPY17_RS10160	COG2003	Belongs to the UPF0758 family
GPY17_RS10165	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GPY17_RS10180	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GPY17_RS10185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPY17_RS10200	COG0463	Glycosyl transferase, family 2
GPY17_RS10205	COG0859	PFAM glycosyl transferase family 9
GPY17_RS10210	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GPY17_RS10215	COG3642	lipopolysaccharide core region biosynthetic process
GPY17_RS10235	COG0110	maltose O-acetyltransferase activity
GPY17_RS10240	COG2030	dehydratase
GPY17_RS10260	COG0438	transferase activity, transferring glycosyl groups
GPY17_RS10260	COG0297	glycogen (starch) synthase activity
GPY17_RS10270	COG1519	Transferase
GPY17_RS10275	COG0859	PFAM glycosyl transferase family 9
GPY17_RS10280	COG1560	Kdo2-lipid A biosynthetic process
GPY17_RS10290	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY17_RS10355	COG1086	Polysaccharide biosynthesis protein
GPY17_RS10380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPY17_RS10395	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GPY17_RS10400	COG0149	triose-phosphate isomerase activity
GPY17_RS10435	COG3074	FtsZ-dependent cytokinesis
GPY17_RS10440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPY17_RS10445	COG1575	Belongs to the MenA family. Type 1 subfamily
GPY17_RS10475	COG2003	Belongs to the UPF0758 family
GPY17_RS10490	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GPY17_RS10495	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GPY17_RS10505	COG1609	Transcriptional regulator
GPY17_RS10510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPY17_RS10520	COG0254	rRNA binding
GPY17_RS10530	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPY17_RS10535	COG0088	Forms part of the polypeptide exit tunnel
GPY17_RS10545	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPY17_RS10550	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPY17_RS10555	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPY17_RS10560	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPY17_RS10570	COG0255	Belongs to the universal ribosomal protein uL29 family
GPY17_RS10575	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPY17_RS10580	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPY17_RS10585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPY17_RS10590	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPY17_RS10595	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPY17_RS10600	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPY17_RS10605	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPY17_RS10620	COG1841	ribosomal large subunit assembly
GPY17_RS10625	COG0200	Binds to the 23S rRNA
GPY17_RS10630	COG0201	protein transport
GPY17_RS10640	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPY17_RS10645	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPY17_RS10655	COG0202	RNA polymerase activity
GPY17_RS10660	COG0203	ribosomal protein L17
GPY17_RS10670	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY17_RS10680	COG2153	protein acetylation
GPY17_RS10685	COG0513	Belongs to the DEAD box helicase family
GPY17_RS10695	COG0737	Belongs to the 5'-nucleotidase family
GPY17_RS10700	COG1648	precorrin-2 dehydrogenase activity
GPY17_RS10700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GPY17_RS10705	COG0175	sulfate reduction
GPY17_RS10710	COG2895	sulfate adenylyltransferase (ATP) activity
GPY17_RS10720	COG0471	metal ion transport
GPY17_RS10720	COG3273	potassium ion transport
GPY17_RS10725	COG0529	Catalyzes the synthesis of activated sulfate
GPY17_RS10745	COG4181	ATPase activity
GPY17_RS10760	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GPY17_RS10770	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY17_RS10775	COG0729	surface antigen
GPY17_RS10780	COG2911	Protein conserved in bacteria
GPY17_RS10785	COG2105	PFAM AIG2 family protein
GPY17_RS10795	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GPY17_RS10800	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GPY17_RS10810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPY17_RS10815	COG0163	prenyltransferase activity
GPY17_RS10820	COG4143	(ABC) transporter
GPY17_RS10825	COG1178	ABC-type Fe3 transport system permease component
GPY17_RS10830	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GPY17_RS10865	COG0039	L-malate dehydrogenase activity
GPY17_RS10875	COG0142	geranyltranstransferase activity
GPY17_RS10880	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GPY17_RS10890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPY17_RS10895	COG2966	Psort location CytoplasmicMembrane, score
GPY17_RS10910	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GPY17_RS10915	COG2967	ApaG domain
GPY17_RS10920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GPY17_RS10925	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GPY17_RS10930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY17_RS10935	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GPY17_RS10940	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPY17_RS10950	COG0066	3-isopropylmalate dehydratase activity
GPY17_RS10955	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPY17_RS10960	COG0473	3-isopropylmalate dehydrogenase activity
GPY17_RS10965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPY17_RS10990	COG0583	DNA-binding transcription factor activity
GPY17_RS10995	COG1022	Amp-dependent synthetase and ligase
GPY17_RS11000	COG0028	Belongs to the TPP enzyme family
GPY17_RS11005	COG0440	acetolactate synthase activity
GPY17_RS11010	COG3706	GGDEF domain
GPY17_RS11020	COG0469	pyruvate kinase activity
GPY17_RS11030	COG1349	DNA-binding transcription factor activity
GPY17_RS11035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GPY17_RS11050	COG5002	protein histidine kinase activity
GPY17_RS11060	COG2376	Dihydroxyacetone kinase
GPY17_RS11065	COG1461	Dihydroxyacetone kinase
GPY17_RS11080	COG3722	fumarate hydratase activity
GPY17_RS11085	COG0246	Mannitol dehydrogenase
GPY17_RS11090	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY17_RS11090	COG2213	PTS system mannitol-specific
GPY17_RS11125	COG1464	Belongs to the NlpA lipoprotein family
GPY17_RS11135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPY17_RS11140	COG0358	DNA primase activity
GPY17_RS11145	COG1610	YqeY-like protein
GPY17_RS11150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GPY17_RS11155	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPY17_RS11160	COG0596	Alpha beta hydrolase
GPY17_RS11165	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GPY17_RS11170	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPY17_RS11175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY17_RS11180	COG1968	undecaprenyl-diphosphatase activity
GPY17_RS11185	COG0617	tRNA 3'-terminal CCA addition
GPY17_RS11190	COG3267	Type II secretory pathway component ExeA
GPY17_RS11190	COG3409	Peptidoglycan-binding domain 1 protein
GPY17_RS11200	COG4991	sh3 domain protein
GPY17_RS11205	COG0306	phosphate transporter
GPY17_RS11210	COG1392	Phosphate transport regulator
GPY17_RS11215	COG3025	triphosphatase activity
GPY17_RS11230	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GPY17_RS11235	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GPY17_RS11235	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GPY17_RS11240	COG1538	Outer membrane efflux protein
GPY17_RS11245	COG0494	nUDIX hydrolase
GPY17_RS11250	COG3151	Protein conserved in bacteria
GPY17_RS11260	COG3150	esterase
GPY17_RS11265	COG0187	DNA topoisomerase II activity
GPY17_RS11270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPY17_RS11275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPY17_RS11285	COG3105	Protein conserved in bacteria
GPY17_RS11295	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GPY17_RS11305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPY17_RS11310	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GPY17_RS11315	COG0723	plastoquinol--plastocyanin reductase activity
GPY17_RS11320	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GPY17_RS11325	COG2857	Cytochrome c1
GPY17_RS11330	COG0625	glutathione transferase activity
GPY17_RS11335	COG2969	positive regulation of protein catabolic process
GPY17_RS11340	COG2823	Periplasmic or secreted lipoprotein
GPY17_RS11345	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPY17_RS11350	COG0792	nuclease activity
GPY17_RS11360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPY17_RS11375	COG0275	rRNA processing
GPY17_RS11380	COG3116	cell division
GPY17_RS11385	COG0768	penicillin binding
GPY17_RS11390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPY17_RS11395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GPY17_RS11400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPY17_RS11405	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPY17_RS11410	COG0772	Belongs to the SEDS family
GPY17_RS11415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPY17_RS11420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GPY17_RS11425	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GPY17_RS11430	COG0849	cell division
GPY17_RS11435	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPY17_RS11440	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GPY17_RS11450	COG0653	protein targeting
GPY17_RS11455	COG0494	nUDIX hydrolase
GPY17_RS11460	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GPY17_RS11465	COG0505	Belongs to the CarA family
GPY17_RS11470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GPY17_RS11485	COG0730	response to heat
GPY17_RS11490	COG0583	DNA-binding transcription factor activity
GPY17_RS11495	COG2860	membrane
GPY17_RS11500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GPY17_RS11510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPY17_RS11520	COG0493	'glutamate synthase
GPY17_RS11525	COG0070	glutamate synthase
GPY17_RS11525	COG0069	glutamate synthase activity
GPY17_RS11525	COG0067	glutamate synthase
GPY17_RS11535	COG0070	glutamate synthase
GPY17_RS11535	COG0069	glutamate synthase activity
GPY17_RS11535	COG0067	glutamate synthase
GPY17_RS11540	COG1242	4 iron, 4 sulfur cluster binding
GPY17_RS11545	COG5001	Diguanylate cyclase
GPY17_RS11545	COG4251	negative regulation of phosphorylation
GPY17_RS11545	COG2203	Gaf domain
GPY17_RS11545	COG3706	GGDEF domain
GPY17_RS11550	COG2198	Histidine kinase
GPY17_RS11550	COG5002	protein histidine kinase activity
GPY17_RS11550	COG0784	Response regulator, receiver
GPY17_RS11560	COG0745	RESPONSE REGULATOR receiver
GPY17_RS11575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GPY17_RS11590	COG0083	homoserine kinase activity
GPY17_RS11595	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPY17_RS11600	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
GPY17_RS11605	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GPY17_RS11615	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPY17_RS11630	COG1115	amino acid carrier protein
GPY17_RS11635	COG3022	response to hydroperoxide
GPY17_RS11640	COG0513	Belongs to the DEAD box helicase family
GPY17_RS11645	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GPY17_RS11655	COG0716	FMN binding
GPY17_RS11665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GPY17_RS11670	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GPY17_RS11680	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GPY17_RS11685	COG2204	response regulator
GPY17_RS11695	COG0667	Aldo Keto reductase
GPY17_RS11705	COG3066	DNA modification
GPY17_RS11715	COG0494	nUDIX hydrolase
GPY17_RS11725	COG0730	response to heat
GPY17_RS11730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPY17_RS11735	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPY17_RS11745	COG1283	sodium-dependent phosphate transmembrane transporter activity
GPY17_RS11750	COG0583	DNA-binding transcription factor activity
GPY17_RS11760	COG0640	Transcriptional regulator
GPY17_RS11770	COG0268	Binds directly to 16S ribosomal RNA
GPY17_RS11775	COG0728	peptidoglycan biosynthetic process
GPY17_RS11780	COG0196	riboflavin kinase activity
GPY17_RS11785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPY17_RS11790	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPY17_RS11795	COG1047	Peptidyl-prolyl cis-trans
GPY17_RS11800	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GPY17_RS11805	COG3279	Response regulator of the LytR AlgR family
GPY17_RS11810	COG3275	phosphorelay sensor kinase activity
GPY17_RS11815	COG1966	Carbon starvation protein
GPY17_RS11830	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPY17_RS11835	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GPY17_RS11840	COG1472	Belongs to the glycosyl hydrolase 3 family
GPY17_RS11845	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY17_RS11850	COG1605	Chorismate mutase
GPY17_RS11850	COG0287	Prephenate dehydrogenase
GPY17_RS11855	COG0739	heme binding
GPY17_RS11870	COG0488	(ABC) transporter
GPY17_RS11880	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GPY17_RS11885	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GPY17_RS11890	COG0077	Prephenate dehydratase
GPY17_RS11890	COG1605	Chorismate mutase
GPY17_RS11895	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY17_RS11900	COG0741	lytic transglycosylase activity
GPY17_RS11905	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY17_RS11910	COG0564	pseudouridine synthase activity
GPY17_RS11920	COG0542	response to heat
GPY17_RS11980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GPY17_RS11990	COG2974	May be involved in recombination
GPY17_RS11995	COG0745	RESPONSE REGULATOR receiver
GPY17_RS12000	COG5002	protein histidine kinase activity
GPY17_RS12010	COG0248	Ppx GppA phosphatase
GPY17_RS12015	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GPY17_RS12025	COG0581	inorganic phosphate transmembrane transporter activity
GPY17_RS12030	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GPY17_RS12035	COG0704	Plays a role in the regulation of phosphate uptake
GPY17_RS12045	COG3142	Participates in the control of copper homeostasis
GPY17_RS12050	COG0450	alkyl hydroperoxide reductase
GPY17_RS12055	COG0583	DNA-binding transcription factor activity
GPY17_RS12065	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GPY17_RS12075	COG0517	IMP dehydrogenase activity
GPY17_RS12085	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPY17_RS12090	COG0343	queuine tRNA-ribosyltransferase activity
GPY17_RS12095	COG1862	Preprotein translocase
GPY17_RS12100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY17_RS12105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPY17_RS12115	COG0483	inositol monophosphate 1-phosphatase activity
GPY17_RS12130	COG1104	cysteine desulfurase activity
GPY17_RS12135	COG0822	iron-sulfur transferase activity
GPY17_RS12145	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GPY17_RS12150	COG0443	Heat shock 70 kDa protein
GPY17_RS12155	COG0633	Ferredoxin
GPY17_RS12160	COG2975	iron-sulfur cluster assembly
GPY17_RS12165	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPY17_RS12170	COG0105	UTP biosynthetic process
GPY17_RS12175	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GPY17_RS12190	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GPY17_RS12195	COG0124	histidyl-tRNA synthetase
GPY17_RS12200	COG2976	Protein conserved in bacteria
GPY17_RS12205	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY17_RS12210	COG1160	GTP binding
GPY17_RS12225	COG1570	exodeoxyribonuclease VII activity
GPY17_RS12230	COG0516	GMP reductase activity
GPY17_RS12230	COG0517	IMP dehydrogenase activity
GPY17_RS12235	COG0519	Catalyzes the synthesis of GMP from XMP
GPY17_RS12235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GPY17_RS12240	COG1757	Na H antiporter
GPY17_RS12250	COG1584	GPR1 FUN34 yaaH family protein
GPY17_RS12260	COG1115	amino acid carrier protein
GPY17_RS12295	COG2873	o-acetylhomoserine
GPY17_RS12300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GPY17_RS12320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPY17_RS12320	COG3153	acetyltransferase
GPY17_RS12325	COG0583	DNA-binding transcription factor activity
GPY17_RS12425	COG2003	Belongs to the UPF0758 family
GPY17_RS12430	COG0328	RNA-DNA hybrid ribonuclease activity
GPY17_RS12450	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GPY17_RS12465	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GPY17_RS12485	COG0582	viral genome integration into host DNA
GPY17_RS12495	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GPY17_RS12500	COG2867	negative regulation of translational initiation
GPY17_RS12505	COG2914	Belongs to the UPF0125 (RnfH) family
GPY17_RS12510	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY17_RS12515	COG0497	DNA recombination
GPY17_RS12525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPY17_RS12530	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPY17_RS12540	COG0443	Heat shock 70 kDa protein
GPY17_RS12545	COG0484	heat shock protein binding
GPY17_RS12580	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY17_RS12585	COG0590	tRNA wobble adenosine to inosine editing
GPY17_RS12595	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GPY17_RS12600	COG0047	phosphoribosylformylglycinamidine synthase activity
GPY17_RS12600	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPY17_RS12625	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY17_RS12630	COG2252	PERMEase
GPY17_RS12635	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GPY17_RS12650	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPY17_RS12655	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPY17_RS12660	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPY17_RS12665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY17_RS12665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPY17_RS12685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPY17_RS12690	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GPY17_RS12695	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GPY17_RS12700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPY17_RS12705	COG0142	geranyltranstransferase activity
GPY17_RS12710	COG1722	exodeoxyribonuclease VII activity
GPY17_RS12715	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GPY17_RS12720	COG2885	chlorophyll binding
GPY17_RS12725	COG0301	tRNA thio-modification
GPY17_RS12725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY17_RS12730	COG0583	DNA-binding transcription factor activity
GPY17_RS12740	COG2363	Small membrane protein
GPY17_RS12745	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GPY17_RS12755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPY17_RS12760	COG1611	Belongs to the LOG family
GPY17_RS12765	COG3706	GGDEF domain
GPY17_RS12765	COG0745	RESPONSE REGULATOR receiver
GPY17_RS12775	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPY17_RS12775	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPY17_RS12785	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GPY17_RS12790	COG1464	Belongs to the NlpA lipoprotein family
GPY17_RS12795	COG2011	ABC-type metal ion transport system permease component
GPY17_RS12800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPY17_RS12810	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPY17_RS12825	COG0366	Alpha amylase catalytic
GPY17_RS12840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPY17_RS12845	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPY17_RS12850	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GPY17_RS12855	COG0321	lipoyl(octanoyl) transferase activity
GPY17_RS12860	COG2921	Belongs to the UPF0250 family
GPY17_RS12865	COG1686	Belongs to the peptidase S11 family
GPY17_RS12870	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GPY17_RS12875	COG0772	Belongs to the SEDS family
GPY17_RS12880	COG0768	penicillin binding
GPY17_RS12885	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPY17_RS12890	COG0799	negative regulation of ribosome biogenesis
GPY17_RS12895	COG1466	dna polymerase III delta subunit
GPY17_RS12900	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GPY17_RS12905	COG0495	leucyl-tRNA aminoacylation
GPY17_RS12910	COG2888	peptidyl-tyrosine sulfation
GPY17_RS12915	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GPY17_RS12920	COG4535	Mg2 and Co2 transporter CorC
GPY17_RS12925	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPY17_RS12930	COG1702	phosphate starvation-inducible protein PhoH
GPY17_RS12935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPY17_RS12945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY17_RS13060	COG0012	GTP binding
GPY17_RS13065	COG0193	aminoacyl-tRNA hydrolase activity
GPY17_RS13070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPY17_RS13075	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPY17_RS13080	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GPY17_RS13085	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPY17_RS13090	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPY17_RS13095	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY17_RS13100	COG3094	Invasion gene expression up-regulator, SirB
GPY17_RS13105	COG2912	Transglutaminase-like superfamily
GPY17_RS13110	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GPY17_RS13115	COG0737	Belongs to the 5'-nucleotidase family
GPY17_RS13125	COG1187	pseudouridine synthase activity
GPY17_RS13130	COG2840	Smr protein MutS2
GPY17_RS13170	COG2608	mercury ion transmembrane transporter activity
GPY17_RS13170	COG2217	Heavy metal translocating P-type atpase
GPY17_RS13185	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPY17_RS13190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY17_RS13250	COG0835	chemotaxis
GPY17_RS13250	COG0784	Response regulator, receiver
GPY17_RS13255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GPY17_RS13260	COG1815	bacterial-type flagellum-dependent cell motility
GPY17_RS13265	COG1558	bacterial-type flagellum-dependent cell motility
GPY17_RS13270	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GPY17_RS13275	COG1749	Flagellar hook protein flgE
GPY17_RS13285	COG4787	bacterial-type flagellum-dependent cell motility
GPY17_RS13290	COG4786	Flagellar basal body rod
GPY17_RS13295	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GPY17_RS13300	COG1706	bacterial-type flagellum-dependent cell motility
GPY17_RS13305	COG3951	Flagellar rod assembly protein muramidase FlgJ
GPY17_RS13305	COG1705	Flagellar rod assembly protein muramidase FlgJ
GPY17_RS13315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY17_RS13325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY17_RS13335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY17_RS13340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY17_RS13350	COG2190	(PTS) system
GPY17_RS13355	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPY17_RS13360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY17_RS13370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GPY17_RS13375	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GPY17_RS13380	COG3115	cell septum assembly
GPY17_RS13385	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPY17_RS13410	COG0330	HflC and HflK could
GPY17_RS13415	COG3118	belongs to the thioredoxin family
GPY17_RS13425	COG0300	oxidoreductase activity
GPY17_RS13430	COG1090	epimerase
GPY17_RS13460	COG0622	Phosphoesterase
GPY17_RS13480	COG3710	Transcriptional regulator
GPY17_RS13485	COG0326	Molecular chaperone. Has ATPase activity
GPY17_RS13490	COG0563	adenylate kinase activity
GPY17_RS13495	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GPY17_RS13500	COG3104	oligopeptide transport
GPY17_RS13505	COG0250	Participates in transcription elongation, termination and antitermination
GPY17_RS13510	COG0367	asparagine synthase
GPY17_RS13515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GPY17_RS13515	COG4651	solute:proton antiporter activity
GPY17_RS13520	COG1940	carbohydrate kinase activity
GPY17_RS13520	COG1846	Transcriptional regulator
GPY17_RS13525	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPY17_RS13535	COG2190	(PTS) system
GPY17_RS13535	COG1263	PTS System
GPY17_RS13535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY17_RS13540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY17_RS13545	COG0735	belongs to the Fur family
GPY17_RS13555	COG0716	FMN binding
GPY17_RS13565	COG0596	Alpha beta hydrolase
GPY17_RS13570	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GPY17_RS13575	COG0033	Phosphoglucomutase
GPY17_RS13585	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPY17_RS13595	COG2009	succinate dehydrogenase
GPY17_RS13600	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GPY17_RS13605	COG1053	succinate dehydrogenase
GPY17_RS13610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPY17_RS13615	COG0567	Dehydrogenase, E1 component
GPY17_RS13620	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY17_RS13625	COG0045	succinate-CoA ligase (ADP-forming) activity
GPY17_RS13635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GPY17_RS13640	COG1121	(ABC) transporter
GPY17_RS13645	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GPY17_RS13650	COG4977	sequence-specific DNA binding
GPY17_RS13665	COG1918	ferrous iron import across plasma membrane
GPY17_RS13685	COG0018	arginyl-trna synthetase
GPY17_RS13695	COG3102	Protein conserved in bacteria
GPY17_RS13710	COG0788	formyltetrahydrofolate deformylase activity
GPY17_RS13715	COG1199	ATP-dependent helicase activity
GPY17_RS13720	COG1214	PFAM Peptidase M22, glycoprotease
GPY17_RS13735	COG2267	carboxylic ester hydrolase activity
GPY17_RS13740	COG0318	PFAM AMP-dependent synthetase and ligase
GPY17_RS13745	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GPY17_RS13750	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GPY17_RS13755	COG2894	cell division
GPY17_RS13760	COG0850	regulation of cytokinetic process
GPY17_RS13765	COG3100	YcgL domain-containing protein
GPY17_RS13770	COG2951	lytic endotransglycosylase activity
GPY17_RS13775	COG0583	DNA-binding transcription factor activity
GPY17_RS13780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY17_RS13785	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPY17_RS13805	COG1028	Short-chain dehydrogenase reductase Sdr
GPY17_RS13810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY17_RS13815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPY17_RS13840	COG2986	histidine ammonia-lyase
GPY17_RS13845	COG1216	Glycosyl transferase, family 2
GPY17_RS13850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY17_RS13865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY17_RS13870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPY17_RS13905	COG1253	flavin adenine dinucleotide binding
GPY17_RS13910	COG0513	Belongs to the DEAD box helicase family
GPY17_RS13915	COG0569	domain protein
GPY17_RS13920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GPY17_RS13940	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GPY17_RS13945	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GPY17_RS13950	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GPY17_RS13955	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GPY17_RS13965	COG2204	response regulator
GPY17_RS13975	COG0544	peptidyl-prolyl cis-trans isomerase activity
GPY17_RS13985	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPY17_RS13990	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPY17_RS13995	COG0776	regulation of translation
GPY17_RS14000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GPY17_RS14005	COG1555	photosystem II stabilization
GPY17_RS14020	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GPY17_RS14025	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GPY17_RS14030	COG0436	Aminotransferase
GPY17_RS14035	COG1169	isochorismate synthase
GPY17_RS14040	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GPY17_RS14045	COG0596	Alpha beta hydrolase
GPY17_RS14050	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPY17_RS14055	COG1441	menaquinone biosynthetic process
GPY17_RS14070	COG2855	membrane
GPY17_RS14075	COG0477	Major facilitator Superfamily
GPY17_RS14120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY17_RS14125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY17_RS14155	COG1522	sequence-specific DNA binding
GPY17_RS14165	COG1946	Acyl-CoA thioesterase
GPY17_RS14170	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GPY17_RS14185	COG2199	diguanylate cyclase activity
GPY17_RS14195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY17_RS14200	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GPY17_RS14205	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GPY17_RS14215	COG0517	IMP dehydrogenase activity
GPY17_RS14215	COG0516	GMP reductase activity
GPY17_RS14245	COG0537	adenosine 5'-monophosphoramidase activity
GPY17_RS14270	COG3150	esterase
GPY17_RS14280	COG1252	NADH dehydrogenase
GPY17_RS14295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPY17_RS14305	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPY17_RS14310	COG1136	(ABC) transporter
GPY17_RS14315	COG4591	ABC-type transport system involved in lipoprotein release permease component
GPY17_RS14325	COG2333	competence protein COMEC
GPY17_RS14325	COG0658	competence protein
GPY17_RS14330	COG1132	(ABC) transporter
GPY17_RS14335	COG1663	tetraacyldisaccharide 4'-kinase activity
GPY17_RS14345	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GPY17_RS14350	COG2719	SpoVR family
GPY17_RS14355	COG2718	Belongs to the UPF0229 family
GPY17_RS14360	COG2766	serine protein kinase
GPY17_RS14370	COG3013	Belongs to the UPF0304 family
GPY17_RS14380	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY17_RS14390	COG1882	Formate acetyltransferase
GPY17_RS14420	COG4215	(ABC) transporter
GPY17_RS14435	COG0708	Exodeoxyribonuclease III
GPY17_RS14445	COG3923	Primosomal replication protein n
GPY17_RS14450	COG0730	response to heat
GPY17_RS14455	COG1199	ATP-dependent helicase activity
GPY17_RS14465	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GPY17_RS14470	COG1187	pseudouridine synthase activity
GPY17_RS14480	COG1278	Cold shock
GPY17_RS14485	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GPY17_RS14490	COG0542	response to heat
GPY17_RS14500	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPY17_RS14505	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GPY17_RS14510	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GPY17_RS14520	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GPY17_RS14535	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPY17_RS14540	COG0297	glycogen (starch) synthase activity
GPY17_RS14560	COG3070	regulator of competence-specific genes
GPY17_RS14565	COG1609	Transcriptional regulator
GPY17_RS14570	COG3381	protein complex oligomerization
GPY17_RS14575	COG0745	RESPONSE REGULATOR receiver
GPY17_RS14580	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPY17_RS14590	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GPY17_RS14595	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GPY17_RS14600	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GPY17_RS14620	COG0189	ligase activity
GPY17_RS14620	COG4067	protein conserved in archaea
GPY17_RS14630	COG0500	methyltransferase
GPY17_RS14635	COG4106	trans-aconitate 2-methyltransferase activity
GPY17_RS14640	COG1801	Protein of unknown function DUF72
GPY17_RS14645	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GPY17_RS14650	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GPY17_RS14655	COG0840	transmembrane signaling receptor activity
GPY17_RS14660	COG0632	four-way junction helicase activity
GPY17_RS14665	COG2255	four-way junction helicase activity
GPY17_RS14670	COG1271	oxidase subunit
GPY17_RS14675	COG1294	oxidase, subunit
GPY17_RS14680	COG4890	Cyd operon protein YbgT
GPY17_RS14690	COG0824	Thioesterase
GPY17_RS14695	COG0811	peptide transport
GPY17_RS14710	COG0823	Involved in the tonB-independent uptake of proteins
GPY17_RS14715	COG2885	chlorophyll binding
GPY17_RS14720	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GPY17_RS14725	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GPY17_RS14735	COG3766	membrane
GPY17_RS14745	COG0754	glutathionylspermidine amidase activity
GPY17_RS14755	COG5002	protein histidine kinase activity
GPY17_RS14755	COG0784	Response regulator, receiver
GPY17_RS14785	COG0328	RNA-DNA hybrid ribonuclease activity
GPY17_RS14800	COG0840	transmembrane signaling receptor activity
GPY17_RS14815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY17_RS14820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY17_RS14850	COG3568	Endonuclease Exonuclease Phosphatase
GPY17_RS14865	COG0583	DNA-binding transcription factor activity
GPY17_RS14875	COG0686	Belongs to the AlaDH PNT family
GPY17_RS14885	COG1674	ftsk spoiiie
GPY17_RS14890	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GPY17_RS14895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GPY17_RS14900	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPY17_RS14905	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY17_RS14915	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPY17_RS14920	COG0156	8-amino-7-oxononanoate synthase activity
GPY17_RS14930	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GPY17_RS14940	COG0501	Belongs to the peptidase M48B family
GPY17_RS14950	COG0300	oxidoreductase activity
GPY17_RS14965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GPY17_RS14990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPY17_RS14995	COG2915	High frequency lysogenization protein hflD homolog
GPY17_RS15000	COG0482	sulfurtransferase activity
GPY17_RS15010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPY17_RS15020	COG1757	Na H antiporter
GPY17_RS15035	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GPY17_RS15040	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPY17_RS15045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPY17_RS15050	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GPY17_RS15050	COG0131	Imidazoleglycerol-phosphate dehydratase
GPY17_RS15055	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPY17_RS15060	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPY17_RS15065	COG0107	imidazoleglycerol-phosphate synthase activity
GPY17_RS15070	COG0140	phosphoribosyl-ATP diphosphatase activity
GPY17_RS15070	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GPY17_RS15075	COG3012	SEC-C Motif Domain Protein
GPY17_RS15085	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY17_RS15090	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY17_RS15095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPY17_RS15100	COG0215	cysteine-tRNA ligase activity
GPY17_RS15105	COG1435	thymidine kinase activity
GPY17_RS15110	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GPY17_RS15135	COG2116	formate transmembrane transporter activity
GPY17_RS15150	COG4459	periplasmic nitrate reductase
GPY17_RS15155	COG3005	denitrification pathway
GPY17_RS15160	COG0243	molybdopterin cofactor binding
GPY17_RS15175	COG1227	inorganic diphosphatase activity
GPY17_RS15185	COG4172	Belongs to the ABC transporter superfamily
GPY17_RS15195	COG4171	peptide transport system, permease
GPY17_RS15200	COG4168	peptide transport system, permease
GPY17_RS15210	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GPY17_RS15215	COG1842	Phage shock protein A
GPY17_RS15225	COG1983	PspC domain protein
GPY17_RS15230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY17_RS15245	COG2818	Glycosylase
GPY17_RS15255	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPY17_RS15260	COG0626	cystathionine gamma-synthase activity
GPY17_RS15270	COG0733	neurotransmitter:sodium symporter activity
GPY17_RS15280	COG0564	pseudouridine synthase activity
GPY17_RS15290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY17_RS15300	COG3604	Transcriptional regulator
GPY17_RS15315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPY17_RS15320	COG4136	ATPase activity
GPY17_RS15325	COG4135	transport system, permease component
GPY17_RS15330	COG4134	Bacterial extracellular solute-binding protein
GPY17_RS15335	COG0398	Pfam SNARE associated Golgi protein
GPY17_RS15345	COG0493	'glutamate synthase
GPY17_RS15370	COG3313	Fe-S protein
GPY17_RS15400	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GPY17_RS15405	COG2205	protein histidine kinase activity
GPY17_RS15410	COG0745	RESPONSE REGULATOR receiver
GPY17_RS15425	COG1187	pseudouridine synthase activity
GPY17_RS15430	COG2814	Major facilitator Superfamily
GPY17_RS15460	COG3005	denitrification pathway
GPY17_RS15470	COG0534	Mate efflux family protein
GPY17_RS15475	COG4181	ATPase activity
GPY17_RS15490	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPY17_RS15505	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GPY17_RS15510	COG3273	potassium ion transport
GPY17_RS15510	COG2985	domain, Protein
GPY17_RS15515	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY17_RS15530	COG1737	Transcriptional regulator
GPY17_RS15535	COG0076	glutamate decarboxylase activity
GPY17_RS15545	COG2431	L-lysine efflux transmembrane transporter activity
GPY17_RS15560	COG3070	regulator of competence-specific genes
GPY17_RS15575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY17_RS15575	COG4191	Histidine kinase
GPY17_RS15585	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPY17_RS15590	COG3048	D-serine ammonia-lyase activity
GPY17_RS15600	COG4988	ABC transporter
GPY17_RS15605	COG0492	ferredoxin-NADP+ reductase activity
GPY17_RS15625	COG0745	RESPONSE REGULATOR receiver
GPY17_RS15625	COG3706	GGDEF domain
GPY17_RS15630	COG0471	metal ion transport
GPY17_RS15635	COG2949	membrane
GPY17_RS15640	COG0281	malic enzyme
GPY17_RS15645	COG1643	Atp-dependent helicase
GPY17_RS15650	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GPY17_RS15665	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GPY17_RS15700	COG0277	FAD linked oxidase domain protein
GPY17_RS15700	COG0247	lactate metabolic process
GPY17_RS15715	COG2986	histidine ammonia-lyase
GPY17_RS15720	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GPY17_RS15725	COG0010	Belongs to the arginase family
GPY17_RS15730	COG1228	amidohydrolase
GPY17_RS15735	COG2188	Transcriptional regulator
GPY17_RS15750	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPY17_RS15760	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GPY17_RS15770	COG0393	Putative heavy-metal-binding
GPY17_RS15800	COG3706	GGDEF domain
GPY17_RS15805	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPY17_RS15810	COG0072	phenylalanine-tRNA ligase activity
GPY17_RS15810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY17_RS15825	COG0776	regulation of translation
GPY17_RS15835	COG0500	methyltransferase
GPY17_RS15840	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GPY17_RS15845	COG0295	cytidine deaminase activity
GPY17_RS15850	COG1346	cytolysis
GPY17_RS15855	COG1380	Effector of murein hydrolase LrgA
GPY17_RS15860	COG2925	Exonuclease
GPY17_RS15870	COG0702	epimerase
GPY17_RS15875	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GPY17_RS15880	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GPY17_RS15905	COG2988	succinylglutamate desuccinylase activity
GPY17_RS15910	COG4139	cobalamin transport
GPY17_RS15915	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GPY17_RS15935	COG0583	DNA-binding transcription factor activity
GPY17_RS15955	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPY17_RS15960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GPY17_RS15965	COG3475	LICD family
GPY17_RS15970	COG1451	nucleotide metabolic process
GPY17_RS15975	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GPY17_RS16005	COG3938	Belongs to the proline racemase family
GPY17_RS16025	COG2423	ornithine cyclodeaminase activity
GPY17_RS16030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPY17_RS16035	COG3842	ATPase activity
GPY17_RS16040	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPY17_RS16045	COG1177	transmembrane transport
GPY17_RS16055	COG3291	Pkd domain containing protein
GPY17_RS16075	COG0444	Belongs to the ABC transporter superfamily
GPY17_RS16080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY17_RS16085	COG0601	transmembrane transport
GPY17_RS16095	COG2195	Cleaves the N-terminal amino acid of tripeptides
GPY17_RS16105	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GPY17_RS16115	COG0625	glutathione transferase activity
GPY17_RS16220	COG1278	Cold shock
GPY17_RS16225	COG0557	exoribonuclease II activity
GPY17_RS16275	COG1783	phage Terminase large subunit
GPY17_RS16490	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GPY17_RS16495	COG0583	DNA-binding transcription factor activity
GPY17_RS16530	COG0471	metal ion transport
GPY17_RS16535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY17_RS16535	COG4191	Histidine kinase
GPY17_RS16545	COG5001	Diguanylate cyclase
GPY17_RS16545	COG3300	MHYT domain
GPY17_RS16555	COG1280	lysine exporter protein (LysE YggA)
GPY17_RS16560	COG1328	CTP reductase activity
GPY17_RS16565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPY17_RS16575	COG0861	Integral membrane protein TerC family
GPY17_RS16585	COG0739	heme binding
GPY17_RS16610	COG2204	response regulator
GPY17_RS16625	COG3501	Rhs element vgr protein
GPY17_RS16650	COG0515	serine threonine protein kinase
GPY17_RS16685	COG1522	sequence-specific DNA binding
GPY17_RS16760	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GPY17_RS16775	COG0814	amino acid
GPY17_RS16800	COG1132	(ABC) transporter
GPY17_RS16805	COG1132	(ABC) transporter
GPY17_RS16835	COG0443	Heat shock 70 kDa protein
GPY17_RS16840	COG0443	Heat shock 70 kDa protein
GPY17_RS16880	COG0243	molybdopterin cofactor binding
GPY17_RS16885	COG0437	4 iron, 4 sulfur cluster binding
GPY17_RS16890	COG3302	dmso reductase anchor subunit
GPY17_RS16905	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPY17_RS16910	COG1643	Atp-dependent helicase
GPY17_RS16925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY17_RS16935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GPY17_RS16940	COG1215	transferase activity, transferring glycosyl groups
GPY17_RS16945	COG0438	transferase activity, transferring glycosyl groups
GPY17_RS16990	COG2204	response regulator
GPY17_RS17025	COG1793	dna ligase
GPY17_RS17035	COG0534	Mate efflux family protein
GPY17_RS17040	COG0307	riboflavin synthase, alpha
GPY17_RS17055	COG2201	protein-glutamate methylesterase activity
GPY17_RS17060	COG3706	GGDEF domain
GPY17_RS17070	COG0791	NLP P60 protein
GPY17_RS17075	COG0840	transmembrane signaling receptor activity
GPY17_RS17075	COG3290	protein histidine kinase activity
GPY17_RS17115	COG1940	carbohydrate kinase activity
GPY17_RS17130	COG0746	molybdenum cofactor guanylyltransferase activity
GPY17_RS17135	COG3842	ATPase activity
GPY17_RS17155	COG2204	response regulator
GPY17_RS17160	COG4191	Histidine kinase
GPY17_RS17170	COG0488	(ABC) transporter
GPY17_RS17175	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPY17_RS17200	COG3381	protein complex oligomerization
GPY17_RS17210	COG3383	formate dehydrogenase (NAD+) activity
GPY17_RS17210	COG0243	molybdopterin cofactor binding
GPY17_RS17215	COG0437	4 iron, 4 sulfur cluster binding
GPY17_RS17230	COG3209	COG3209 Rhs family protein
GPY17_RS17270	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GPY17_RS17275	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY17_RS17280	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GPY17_RS17285	COG1177	transmembrane transport
GPY17_RS17290	COG1176	ABC-type spermidine putrescine transport system, permease component I
GPY17_RS17295	COG3842	ATPase activity
GPY17_RS17315	COG0037	tRNA processing
GPY17_RS17325	COG0589	response to stress
GPY17_RS17330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY17_RS17345	COG2217	Heavy metal translocating P-type atpase
GPY17_RS17355	COG2010	Cytochrome c
GPY17_RS17370	COG3278	Belongs to the heme-copper respiratory oxidase family
GPY17_RS17410	COG3120	sequence-specific DNA binding
GPY17_RS17415	COG1067	ATP-dependent peptidase activity
GPY17_RS17420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY17_RS17445	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY17_RS17445	COG0116	Belongs to the methyltransferase superfamily
GPY17_RS17460	COG0167	dihydroorotate dehydrogenase activity
GPY17_RS17465	COG2902	Dehydrogenase
GPY17_RS17475	COG0308	aminopeptidase N
GPY17_RS17490	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GPY17_RS17495	COG1956	GAF domain-containing protein
GPY17_RS17500	COG1132	(ABC) transporter
GPY17_RS17505	COG2995	paraquat-inducible protein a
GPY17_RS17510	COG3008	intermembrane lipid transfer
GPY17_RS17515	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GPY17_RS17515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPY17_RS17535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPY17_RS17540	COG1666	GTP binding
GPY17_RS17555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY17_RS17560	COG4597	amino acid ABC transporter
GPY17_RS17565	COG0765	amino acid transport
GPY17_RS17570	COG1126	abc transporter atp-binding protein
GPY17_RS17575	COG0670	Belongs to the BI1 family
GPY17_RS17585	COG2920	part of a sulfur-relay system
GPY17_RS17590	COG1254	Belongs to the acylphosphatase family
GPY17_RS17595	COG0840	transmembrane signaling receptor activity
GPY17_RS17600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GPY17_RS17640	COG3706	GGDEF domain
GPY17_RS17645	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPY17_RS17650	COG0602	queuosine metabolic process
GPY17_RS17655	COG0561	phosphatase activity
GPY17_RS17680	COG2828	Protein conserved in bacteria
GPY17_RS17690	COG0372	Belongs to the citrate synthase family
GPY17_RS17695	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPY17_RS17725	COG0730	response to heat
GPY17_RS17745	COG0457	Tetratricopeptide repeat
GPY17_RS17810	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY17_RS17815	COG4790	Type iii secretion
GPY17_RS17820	COG4794	Type iii secretion
GPY17_RS17825	COG4791	protein targeting
GPY17_RS17830	COG4792	protein secretion
GPY17_RS17840	COG1073	alpha beta
GPY17_RS17845	COG1073	alpha beta
GPY17_RS17885	COG3177	Filamentation induced by cAMP protein fic
GPY17_RS17905	COG4669	(LipO)protein
GPY17_RS17975	COG1012	belongs to the aldehyde dehydrogenase family
GPY17_RS17980	COG3284	Transcriptional regulator
GPY17_RS18010	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPY17_RS18015	COG0363	glucosamine-6-phosphate deaminase activity
GPY17_RS18020	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPY17_RS18025	COG4565	transcriptional regulatory protein
GPY17_RS18030	COG3290	protein histidine kinase activity
GPY17_RS18045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY17_RS18060	COG1858	cytochrome C peroxidase
GPY17_RS18065	COG0527	aspartate kinase activity
GPY17_RS18075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPY17_RS18080	COG0456	acetyltransferase
GPY17_RS18085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY17_RS18105	COG4176	ABC-type proline glycine betaine transport system permease component
GPY17_RS18110	COG2113	Glycine betaine
GPY17_RS18130	COG1028	Short-chain dehydrogenase reductase Sdr
GPY17_RS18140	COG0745	RESPONSE REGULATOR receiver
GPY17_RS18145	COG0642	Histidine kinase
GPY17_RS18150	COG1368	sulfuric ester hydrolase activity
GPY17_RS18175	COG1115	amino acid carrier protein
GPY17_RS18185	COG1280	lysine exporter protein (LysE YggA)
GPY17_RS18190	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GPY17_RS18195	COG1560	Kdo2-lipid A biosynthetic process
GPY17_RS18205	COG0531	amino acid
GPY17_RS18220	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GPY17_RS18225	COG3063	Type IV pilus biogenesis stability protein PilW
GPY17_RS18255	COG0110	maltose O-acetyltransferase activity
GPY17_RS18275	COG2315	Protein conserved in bacteria
GPY17_RS18280	COG1846	Transcriptional regulator
GPY17_RS18295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPY17_RS18305	COG2771	luxR family
GPY17_RS18305	COG2200	EAL domain
GPY17_RS18315	COG1227	inorganic diphosphatase activity
GPY17_RS18320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPY17_RS18325	COG1012	belongs to the aldehyde dehydrogenase family
GPY17_RS18330	COG2957	Belongs to the agmatine deiminase family
GPY17_RS18340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY17_RS18345	COG1012	belongs to the aldehyde dehydrogenase family
GPY17_RS18350	COG1396	sequence-specific DNA binding
GPY17_RS18350	COG1917	Cupin 2, conserved barrel domain protein
GPY17_RS18355	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GPY17_RS18365	COG0174	glutamine synthetase
GPY17_RS18370	COG1757	Na H antiporter
GPY17_RS18390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY17_RS18395	COG1280	lysine exporter protein (LysE YggA)
GPY17_RS18420	COG2801	Transposase and inactivated derivatives
GPY17_RS18510	COG2226	methyltransferase
GPY17_RS18730	COG1280	lysine exporter protein (LysE YggA)
GPY17_RS18775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPY17_RS18785	COG3768	UPF0283 membrane protein
GPY17_RS18790	COG3106	COG3106 Predicted ATPase
GPY17_RS18810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY17_RS18815	COG0784	Response regulator, receiver
GPY17_RS18815	COG2205	protein histidine kinase activity
GPY17_RS18825	COG0494	nUDIX hydrolase
GPY17_RS18830	COG0814	amino acid
GPY17_RS18835	COG1760	l-serine dehydratase
GPY17_RS18840	COG2200	EAL domain
GPY17_RS18850	COG0720	synthase
GPY17_RS18855	COG0840	transmembrane signaling receptor activity
GPY17_RS18860	COG0017	Asparaginyl-tRNA synthetase
GPY17_RS18870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GPY17_RS18895	COG1448	Aminotransferase
GPY17_RS18915	COG0840	transmembrane signaling receptor activity
GPY17_RS18920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GPY17_RS18925	COG1846	Transcriptional regulator
GPY17_RS18965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY17_RS18970	COG3108	Peptidase M15
GPY17_RS18975	COG2989	Protein conserved in bacteria
GPY17_RS19000	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPY17_RS19010	COG4235	cytochrome complex assembly
GPY17_RS19010	COG3088	subunit of a heme lyase
GPY17_RS19020	COG1138	Cytochrome C-type biogenesis protein
GPY17_RS19025	COG3301	Polysulphide reductase, NrfD
GPY17_RS19030	COG0437	4 iron, 4 sulfur cluster binding
GPY17_RS19040	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GPY17_RS19060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GPY17_RS19065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY17_RS19070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPY17_RS19095	COG0019	diaminopimelate decarboxylase activity
GPY17_RS19135	COG0322	excinuclease ABC activity
GPY17_RS19140	COG2197	response regulator
GPY17_RS19145	COG0417	DNA replication proofreading
GPY17_RS19155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPY17_RS19160	COG3099	Belongs to the UPF0263 family
GPY17_RS19170	COG1187	pseudouridine synthase activity
GPY17_RS19180	COG0009	L-threonylcarbamoyladenylate synthase
GPY17_RS19185	COG0613	PHP domain protein
GPY17_RS19195	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPY17_RS19200	COG0512	Glutamine amidotransferase of anthranilate synthase
GPY17_RS19205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPY17_RS19210	COG0135	phosphoribosylanthranilate isomerase activity
GPY17_RS19210	COG0134	indole-3-glycerol-phosphate synthase activity
GPY17_RS19215	COG0133	tryptophan synthase activity
GPY17_RS19220	COG0159	tryptophan synthase activity
GPY17_RS19230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY17_RS19235	COG0318	PFAM AMP-dependent synthetase and ligase
GPY17_RS19245	COG1301	dicarboxylic acid transport
GPY17_RS19265	COG2917	probably involved in intracellular septation
GPY17_RS19270	COG1607	acyl-coa hydrolase
GPY17_RS19275	COG2350	Protein conserved in bacteria
GPY17_RS19285	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPY17_RS19295	COG0583	DNA-binding transcription factor activity
GPY17_RS19310	COG2203	Gaf domain
GPY17_RS19310	COG5001	Diguanylate cyclase
GPY17_RS19310	COG4251	negative regulation of phosphorylation
GPY17_RS19310	COG3706	GGDEF domain
GPY17_RS19315	COG1032	radical SAM domain protein
GPY17_RS19320	COG0840	transmembrane signaling receptor activity
GPY17_RS19330	COG0745	RESPONSE REGULATOR receiver
GPY17_RS19335	COG5002	protein histidine kinase activity
GPY17_RS19335	COG3850	Histidine kinase
GPY17_RS19370	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPY17_RS19385	COG1335	isochorismatase
GPY17_RS19390	COG1136	(ABC) transporter
GPY17_RS19390	COG0577	efflux transmembrane transporter activity
GPY17_RS19400	COG1136	(ABC) transporter
GPY17_RS19400	COG0577	efflux transmembrane transporter activity
GPY17_RS19410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPY17_RS19440	COG3118	belongs to the thioredoxin family
GPY17_RS19445	COG4232	protein-disulfide reductase activity
GPY17_RS19485	COG2863	cytochrome
GPY17_RS19490	COG3258	Cytochrome c
GPY17_RS19495	COG2995	paraquat-inducible protein a
GPY17_RS19500	COG3008	intermembrane lipid transfer
GPY17_RS19500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPY17_RS19510	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GPY17_RS19520	COG0463	Glycosyl transferase, family 2
GPY17_RS19535	COG4166	transmembrane transport
GPY17_RS19540	COG0284	orotidine-5'-phosphate decarboxylase activity
GPY17_RS19545	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GPY17_RS19550	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GPY17_RS19560	COG0539	negative regulation of cytoplasmic translation
GPY17_RS19565	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GPY17_RS19570	COG0616	signal peptide processing
GPY17_RS19575	COG1028	Short-chain dehydrogenase reductase Sdr
GPY17_RS19590	COG0587	DNA-directed DNA polymerase activity
GPY17_RS19595	COG0784	Response regulator, receiver
GPY17_RS19595	COG0835	chemotaxis
GPY17_RS19600	COG1940	carbohydrate kinase activity
GPY17_RS19605	COG0469	pyruvate kinase activity
GPY17_RS19610	COG4667	esterase of the alpha-beta hydrolase superfamily
GPY17_RS19625	COG0733	neurotransmitter:sodium symporter activity
GPY17_RS19645	COG1263	PTS System
GPY17_RS19645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GPY17_RS19650	COG0084	hydrolase, TatD family'
GPY17_RS19660	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPY17_RS19665	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPY17_RS19695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPY17_RS19700	COG0416	fatty acid biosynthetic process
GPY17_RS19710	COG1399	metal-binding, possibly nucleic acid-binding protein
GPY17_RS19715	COG0424	maF-like protein
GPY17_RS19720	COG0564	pseudouridine synthase activity
GPY17_RS19725	COG1530	ribonuclease E activity
GPY17_RS19730	COG0659	secondary active sulfate transmembrane transporter activity
GPY17_RS19735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPY17_RS19740	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GPY17_RS19750	COG0572	uridine kinase
GPY17_RS19755	COG0489	protein tyrosine kinase activity
GPY17_RS19760	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY17_RS19760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY17_RS19770	COG2186	Transcriptional regulator
GPY17_RS19775	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPY17_RS19780	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GPY17_RS19785	COG3012	SEC-C Motif Domain Protein
GPY17_RS19785	COG3318	Belongs to the UPF0149 family
GPY17_RS19790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY17_RS19795	COG3706	GGDEF domain
GPY17_RS19795	COG0745	RESPONSE REGULATOR receiver
GPY17_RS19800	COG0366	Alpha amylase catalytic
GPY17_RS19805	COG1122	ATPase activity
GPY17_RS19810	COG4120	Belongs to the binding-protein-dependent transport system permease family
GPY17_RS19820	COG3092	negative regulation of chromosome organization
GPY17_RS19825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPY17_RS19830	COG0857	belongs to the CobB CobQ family
GPY17_RS19830	COG0280	phosphate acetyltransferase
GPY17_RS19835	COG3174	membrane
GPY17_RS19845	COG0435	Glutathione S-transferase
GPY17_RS19855	COG0444	Belongs to the ABC transporter superfamily
GPY17_RS19860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY17_RS19865	COG0601	transmembrane transport
GPY17_RS19875	COG0314	molybdopterin synthase activity
GPY17_RS19880	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPY17_RS19885	COG0315	cyclic pyranopterin monophosphate synthase activity
GPY17_RS19890	COG0521	Mo-molybdopterin cofactor biosynthetic process
GPY17_RS19895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPY17_RS19900	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GPY17_RS19905	COG2198	Histidine kinase
GPY17_RS19910	COG2204	response regulator
GPY17_RS19915	COG0556	nucleotide-excision repair
GPY17_RS19930	COG4657	Part of a membrane complex involved in electron transport
GPY17_RS19935	COG2878	Part of a membrane complex involved in electron transport
GPY17_RS19940	COG4656	Part of a membrane complex involved in electron transport
GPY17_RS19945	COG4658	electron transport chain
GPY17_RS19950	COG4659	FMN binding
GPY17_RS19955	COG4660	Part of a membrane complex involved in electron transport
GPY17_RS19960	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPY17_RS19965	COG0346	lactoylglutathione lyase activity
GPY17_RS19975	COG2885	chlorophyll binding
GPY17_RS19990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPY17_RS19995	COG2056	Na+-H+ antiporter family
GPY17_RS20005	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GPY17_RS20025	COG1012	belongs to the aldehyde dehydrogenase family
GPY17_RS20025	COG1454	alcohol dehydrogenase
GPY17_RS20030	COG2095	MarC family integral membrane protein
GPY17_RS20035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY17_RS20040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPY17_RS20045	COG1757	Na H antiporter
GPY17_RS20060	COG3081	Nucleoid-associated protein
GPY17_RS20065	COG3082	Protein of unknown function (DUF1414)
GPY17_RS20070	COG3083	sulfuric ester hydrolase activity
GPY17_RS20080	COG0123	including yeast histone deacetylase and acetoin utilization protein
GPY17_RS20100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPY17_RS20105	COG0778	Nitroreductase
GPY17_RS20110	COG0446	pyridine nucleotide-disulphide oxidoreductase
GPY17_RS20110	COG1902	pentaerythritol trinitrate reductase activity
GPY17_RS20115	COG0616	signal peptide processing
GPY17_RS20120	COG0252	asparaginase activity
GPY17_RS20125	COG3139	Protein of unknown function (DUF1315)
GPY17_RS20135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPY17_RS20140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY17_RS20155	COG2226	methyltransferase
GPY17_RS20175	COG1785	Belongs to the alkaline phosphatase family
GPY17_RS20185	COG0346	lactoylglutathione lyase activity
GPY17_RS20195	COG0668	transmembrane transport
GPY17_RS20200	COG2983	Belongs to the UPF0260 family
GPY17_RS20205	COG2261	transglycosylase associated protein
GPY17_RS20220	COG3681	Belongs to the UPF0597 family
GPY17_RS20225	COG0251	oxidation-reduction process
GPY17_RS20235	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPY17_RS20240	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPY17_RS20245	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPY17_RS20255	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPY17_RS20260	COG2832	Protein of unknown function (DUF454)
GPY17_RS20270	COG0745	RESPONSE REGULATOR receiver
GPY17_RS20275	COG0583	DNA-binding transcription factor activity
GPY17_RS20280	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPY17_RS20285	COG1286	toxin biosynthetic process
GPY17_RS20290	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GPY17_RS20295	COG0285	dihydrofolate synthase activity
GPY17_RS20300	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPY17_RS20305	COG0101	tRNA pseudouridine synthase activity
GPY17_RS20315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPY17_RS20320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY17_RS20325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GPY17_RS20330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GPY17_RS20330	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GPY17_RS20335	COG0431	NADPH-dependent FMN reductase
GPY17_RS20350	COG3101	peptidyl-lysine hydroxylation
GPY17_RS20360	COG2860	membrane
GPY17_RS20365	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPY17_RS20370	COG2890	protein-(glutamine-N5) methyltransferase activity
GPY17_RS20375	COG2840	Smr protein MutS2
GPY17_RS20380	COG2062	phosphohistidine phosphatase, SixA
GPY17_RS20395	COG1024	Enoyl-CoA hydratase
GPY17_RS20395	COG1250	3-hydroxyacyl-CoA dehydrogenase
GPY17_RS20400	COG0183	Belongs to the thiolase family
GPY17_RS20415	COG2067	long-chain fatty acid transport protein
GPY17_RS20420	COG2067	long-chain fatty acid transport protein
GPY17_RS20425	COG2853	Lipoprotein
GPY17_RS20440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GPY17_RS20445	COG1138	Cytochrome C-type biogenesis protein
GPY17_RS20450	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GPY17_RS20455	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY17_RS20460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY17_RS20465	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GPY17_RS20470	COG4133	protoheme IX ABC transporter activity
GPY17_RS20480	COG0835	chemotaxis
GPY17_RS20490	COG1192	Involved in chromosome partitioning
GPY17_RS20495	COG2201	protein-glutamate methylesterase activity
GPY17_RS20500	COG2198	Histidine kinase
GPY17_RS20500	COG0643	Histidine kinase
GPY17_RS20505	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GPY17_RS20520	COG0455	bacterial-type flagellum organization
GPY17_RS20540	COG1684	flagellar biosynthetic protein fliR
GPY17_RS20545	COG1987	bacterial-type flagellum assembly
GPY17_RS20595	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPY17_RS20605	COG1677	Flagellar hook-basal body complex protein FliE
GPY17_RS20610	COG2204	response regulator
GPY17_RS20615	COG4191	Histidine kinase
GPY17_RS20625	COG1516	flagellar protein fliS
GPY17_RS20635	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPY17_RS20640	COG1334	flagellar protein FlaG
GPY17_RS20645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY17_RS20650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPY17_RS20665	COG2837	iron assimilation
GPY17_RS20695	COG1393	Belongs to the ArsC family
GPY17_RS20700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY17_RS20720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPY17_RS20725	COG2716	regulation of RNA biosynthetic process
GPY17_RS20730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPY17_RS20745	COG4783	chaperone-mediated protein folding
GPY17_RS20750	COG1393	Belongs to the ArsC family
GPY17_RS20770	COG2233	PERMEase
GPY17_RS20775	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPY17_RS20780	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GPY17_RS20785	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPY17_RS20790	COG0121	glutamine amidotransferase
GPY17_RS20795	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GPY17_RS20800	COG1960	acyl-CoA dehydrogenase activity
GPY17_RS20830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPY17_RS20835	COG0328	RNA-DNA hybrid ribonuclease activity
GPY17_RS20845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GPY17_RS20850	COG0741	lytic transglycosylase activity
GPY17_RS20850	COG1388	LysM domain
GPY17_RS20860	COG3021	interspecies interaction between organisms
GPY17_RS20865	COG0347	Belongs to the P(II) protein family
GPY17_RS20875	COG0037	tRNA processing
GPY17_RS20880	COG0825	malonyl-CoA metabolic process
GPY17_RS20885	COG0587	DNA-directed DNA polymerase activity
GPY17_RS20895	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY17_RS20900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GPY17_RS20905	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GPY17_RS20910	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GPY17_RS20920	COG0750	zinc metalloprotease
GPY17_RS20925	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GPY17_RS20930	COG0575	Belongs to the CDS family
GPY17_RS20935	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPY17_RS20940	COG0233	cytoplasmic translational termination
GPY17_RS20945	COG0528	UMP kinase activity
GPY17_RS20950	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPY17_RS20955	COG0052	Belongs to the universal ribosomal protein uS2 family
GPY17_RS20960	COG0024	Methionine aminopeptidase
GPY17_RS20965	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GPY17_RS20975	COG0564	pseudouridine synthase activity
GPY17_RS20980	COG3098	single-species biofilm formation
GPY17_RS21005	COG1671	Belongs to the UPF0178 family
GPY17_RS21010	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GPY17_RS21025	COG0254	rRNA binding
GPY17_RS21030	COG1720	tRNA m6t6A37 methyltransferase activity
GPY17_RS21035	COG0442	prolyl-tRNA aminoacylation
GPY17_RS21055	COG0733	neurotransmitter:sodium symporter activity
GPY17_RS21070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY17_RS21075	COG0514	ATP-dependent DNA helicase (RecQ)
GPY17_RS21080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPY17_RS21095	COG1477	protein flavinylation
GPY17_RS21100	COG2871	sodium ion transport
GPY17_RS21105	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY17_RS21110	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY17_RS21115	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY17_RS21120	COG1805	sodium ion transport
GPY17_RS21125	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GPY17_RS21130	COG0271	Belongs to the BolA IbaG family
GPY17_RS21135	COG2813	Specifically methylates the guanine in position
GPY17_RS21140	COG3056	Lipoprotein
GPY17_RS21160	COG1595	DNA-templated transcription, initiation
GPY17_RS21185	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPY17_RS21190	COG0693	protein deglycase activity
GPY17_RS21195	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPY17_RS21200	COG3706	GGDEF domain
GPY17_RS21205	COG2166	iron-sulfur cluster assembly
GPY17_RS21210	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GPY17_RS21215	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GPY17_RS21235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GPY17_RS21240	COG1074	ATP-dependent DNA helicase activity
GPY17_RS21245	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GPY17_RS21265	COG3141	response to X-ray
GPY17_RS21270	COG2171	N-acyltransferase activity
GPY17_RS21275	COG0584	glycerophosphoryl diester phosphodiesterase
GPY17_RS21280	COG2271	Major facilitator Superfamily
GPY17_RS21295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GPY17_RS21300	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPY17_RS21305	COG1349	DNA-binding transcription factor activity
GPY17_RS21310	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPY17_RS21315	COG0598	Magnesium transport protein CorA
GPY17_RS21330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPY17_RS21335	COG1609	Transcriptional regulator
GPY17_RS21340	COG2211	Major facilitator Superfamily
GPY17_RS21355	COG2017	converts alpha-aldose to the beta-anomer
GPY17_RS21360	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPY17_RS21370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GPY17_RS21380	COG1609	Transcriptional regulator
GPY17_RS21385	COG3250	beta-galactosidase activity
GPY17_RS21390	COG2731	YhcH YjgK YiaL family protein
GPY17_RS21395	COG0531	amino acid
GPY17_RS21400	COG0583	DNA-binding transcription factor activity
GPY17_RS21460	COG4964	Belongs to the GSP D family
GPY17_RS21485	COG2169	Transcriptional regulator
GPY17_RS21500	COG0583	DNA-binding transcription factor activity
GPY17_RS21505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPY17_RS21510	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPY17_RS21520	COG0560	Phosphoserine phosphatase
GPY17_RS21530	COG0813	purine-nucleoside phosphorylase activity
GPY17_RS21535	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPY17_RS21540	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GPY17_RS21545	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPY17_RS21550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPY17_RS21555	COG0084	hydrolase, TatD family'
GPY17_RS21565	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GPY17_RS21575	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
GPY17_RS21585	COG3153	acetyltransferase
GPY17_RS21610	COG0534	Mate efflux family protein
GPY17_RS21620	COG4785	May be involved in cell division
GPY17_RS21625	COG1185	polyribonucleotide nucleotidyltransferase activity
GPY17_RS21630	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPY17_RS21635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPY17_RS21640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPY17_RS21645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPY17_RS21650	COG0195	Participates in both transcription termination and antitermination
GPY17_RS21655	COG0779	Required for maturation of 30S ribosomal subunits
GPY17_RS21670	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY17_RS21680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY17_RS21685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPY17_RS21690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPY17_RS21695	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GPY17_RS21700	COG1534	Rna-binding protein
GPY17_RS21705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GPY17_RS21710	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GPY17_RS21715	COG2027	D-alanyl-D-alanine carboxypeptidase
GPY17_RS21725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPY17_RS21730	COG0739	heme binding
GPY17_RS21735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPY17_RS21745	COG0316	Belongs to the HesB IscA family
GPY17_RS21750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GPY17_RS21755	COG0628	permease
GPY17_RS21760	COG2813	Specifically methylates the guanine in position
GPY17_RS21765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GPY17_RS21765	COG2198	Histidine kinase
GPY17_RS21765	COG2205	protein histidine kinase activity
GPY17_RS21765	COG0784	Response regulator, receiver
GPY17_RS21770	COG0747	negative chemotaxis
GPY17_RS21780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPY17_RS21785	COG0444	Belongs to the ABC transporter superfamily
GPY17_RS21790	COG4608	Belongs to the ABC transporter superfamily
GPY17_RS21800	COG2971	BadF BadG BcrA BcrD
GPY17_RS21815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPY17_RS21820	COG3842	ATPase activity
GPY17_RS21830	COG1840	ABC-type Fe3 transport system, periplasmic component
GPY17_RS21845	COG3112	Uncharacterised protein family (UPF0231)
GPY17_RS21850	COG1049	propionate catabolic process, 2-methylcitrate cycle
GPY17_RS21855	COG1752	Esterase of the alpha-beta hydrolase superfamily
GPY17_RS21860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GPY17_RS21865	COG1643	Atp-dependent helicase
GPY17_RS21870	COG1489	DNA binding
GPY17_RS21875	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY17_RS21885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPY17_RS21900	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY17_RS21905	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GPY17_RS21910	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GPY17_RS21920	COG1560	Kdo2-lipid A biosynthetic process
GPY17_RS21925	COG0842	Transport permease protein
GPY17_RS21930	COG1131	(ABC) transporter
GPY17_RS21940	COG0659	secondary active sulfate transmembrane transporter activity
GPY17_RS21945	COG0288	reversible hydration of carbon dioxide
GPY17_RS21960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY17_RS21965	COG0508	dehydrogenase complex catalyzes the overall conversion of
GPY17_RS21970	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GPY17_RS21975	COG2186	Transcriptional regulator
GPY17_RS21985	COG0157	Belongs to the NadC ModD family
GPY17_RS21995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY17_RS22000	COG1459	type II secretion system
GPY17_RS22010	COG0237	dephospho-CoA kinase activity
GPY17_RS22015	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GPY17_RS22020	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GPY17_RS22025	COG0335	large ribosomal subunit rRNA binding
GPY17_RS22030	COG0336	Belongs to the RNA methyltransferase TrmD family
GPY17_RS22035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPY17_RS22040	COG0228	four-way junction DNA binding
GPY17_RS22045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPY17_RS22050	COG4137	Cytochrome C assembly protein
GPY17_RS22055	COG4536	flavin adenine dinucleotide binding
GPY17_RS22060	COG1854	S-ribosylhomocysteine lyase activity
GPY17_RS22070	COG2918	glutathione biosynthetic process
GPY17_RS22075	COG0612	Peptidase, M16
GPY17_RS22080	COG1238	metal cluster binding
GPY17_RS22085	COG1063	alcohol dehydrogenase
GPY17_RS22090	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GPY17_RS22095	COG0511	ligase activity, forming carbon-carbon bonds
GPY17_RS22095	COG5016	pyruvate
GPY17_RS22100	COG3630	sodium ion export across plasma membrane
GPY17_RS22160	COG0527	aspartate kinase activity
GPY17_RS22165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPY17_RS22170	COG2137	regulation of response to DNA damage stimulus
GPY17_RS22175	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPY17_RS22180	COG1546	Belongs to the CinA family
GPY17_RS22185	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPY17_RS22200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GPY17_RS22205	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GPY17_RS22210	COG0585	pseudouridine synthase activity
GPY17_RS22215	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GPY17_RS22220	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GPY17_RS22225	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GPY17_RS22230	COG0148	phosphopyruvate hydratase activity
GPY17_RS22235	COG0504	CTP synthase activity
GPY17_RS22240	COG3956	TIGRFAM MazG family protein
GPY17_RS22245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPY17_RS22255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY17_RS22265	COG0736	holo-[acyl-carrier-protein] synthase activity
GPY17_RS22270	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GPY17_RS22275	COG1381	Involved in DNA repair and RecF pathway recombination
GPY17_RS22280	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPY17_RS22285	COG0571	ribonuclease III activity
GPY17_RS22290	COG0681	Belongs to the peptidase S26 family
GPY17_RS22295	COG0481	GTPase activity
GPY17_RS22300	COG3086	response to oxidative stress
GPY17_RS22310	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GPY17_RS22315	COG1595	DNA-templated transcription, initiation
GPY17_RS22325	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GPY17_RS22335	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GPY17_RS22340	COG0354	folic acid binding
GPY17_RS22355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY17_RS22360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GPY17_RS22365	COG3079	Belongs to the UPF0149 family
GPY17_RS22375	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPY17_RS22385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPY17_RS22390	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GPY17_RS22395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY17_RS22405	COG0583	DNA-binding transcription factor activity
GPY17_RS22415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPY17_RS22420	COG0668	transmembrane transport
GPY17_RS22425	COG0191	fructose-bisphosphate aldolase activity
GPY17_RS22430	COG0126	phosphoglycerate kinase activity
GPY17_RS22435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY17_RS22440	COG4771	TonB-dependent receptor
GPY17_RS22445	COG0583	DNA-binding transcription factor activity
GPY17_RS22450	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPY17_RS22460	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPY17_RS22470	COG3091	SprT-like family
GPY17_RS22475	COG2356	endonuclease I
GPY17_RS22480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GPY17_RS22485	COG0189	ligase activity
GPY17_RS22490	COG1678	Uncharacterized ACR, COG1678
GPY17_RS22495	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPY17_RS22510	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPY17_RS22515	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPY17_RS22520	COG0762	integral membrane protein
GPY17_RS22525	COG1872	DUF167
GPY17_RS22535	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPY17_RS22540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GPY17_RS22545	COG2066	Belongs to the glutaminase family
GPY17_RS22555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GPY17_RS22565	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GPY17_RS22570	COG0741	lytic transglycosylase activity
GPY17_RS22640	COG1012	belongs to the aldehyde dehydrogenase family
GPY17_RS22690	COG3437	response regulator, receiver
GPY17_RS22700	COG3394	polysaccharide catabolic process
GPY17_RS22705	COG1486	melibiose metabolic process
GPY17_RS22710	COG1447	Phosphotransferase system cellobiose-specific component IIA
GPY17_RS22715	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPY17_RS22720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GPY17_RS22725	COG0726	polysaccharide deacetylase
GPY17_RS22735	COG1028	Short-chain dehydrogenase reductase Sdr
GPY17_RS22740	COG4325	translation initiation factor activity
GPY17_RS22750	COG0795	lipopolysaccharide-transporting ATPase activity
GPY17_RS22755	COG0795	lipopolysaccharide-transporting ATPase activity
GPY17_RS22760	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPY17_RS22765	COG2927	DNA polymerase III (CHI subunit)
GPY17_RS22770	COG0525	valine-tRNA ligase activity
GPY17_RS22800	COG2235	arginine
GPY17_RS22805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPY17_RS22815	COG0540	Belongs to the ATCase OTCase family
GPY17_RS22820	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GPY17_RS22825	COG0251	oxidation-reduction process
GPY17_RS22830	COG0204	Acyl-transferase
GPY17_RS22835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPY17_RS22840	COG5007	Belongs to the BolA IbaG family
GPY17_RS22850	COG2854	intermembrane phospholipid transfer
GPY17_RS22855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GPY17_RS22860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GPY17_RS22865	COG1127	ABC transporter
GPY17_RS22875	COG0517	IMP dehydrogenase activity
GPY17_RS22875	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GPY17_RS22885	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GPY17_RS22890	COG1137	ATPase activity
GPY17_RS22900	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPY17_RS22905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY17_RS22910	COG1660	Displays ATPase and GTPase activities
GPY17_RS22915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GPY17_RS22920	COG2239	Acts as a magnesium transporter
GPY17_RS22925	COG0312	modulator of DNA gyrase
GPY17_RS22930	COG3028	Belongs to the UPF0307 family
GPY17_RS22935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPY17_RS22940	COG0564	pseudouridine synthase activity
GPY17_RS22955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GPY17_RS22960	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GPY17_RS22965	COG0312	modulator of DNA gyrase
GPY17_RS22970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPY17_RS22975	COG3164	Protein of unknown function
GPY17_RS22980	COG1530	ribonuclease E activity
GPY17_RS22985	COG0424	maF-like protein
GPY17_RS22990	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GPY17_RS22995	COG1792	Involved in formation and maintenance of cell shape
GPY17_RS23000	COG1077	Cell shape determining protein MreB Mrl
GPY17_RS23045	COG1459	type II secretion system
GPY17_RS23050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPY17_RS23060	COG3409	Peptidoglycan-binding domain 1 protein
GPY17_RS23060	COG3267	Type II secretory pathway component ExeA
GPY17_RS23085	COG2200	EAL domain
GPY17_RS23085	COG2199	diguanylate cyclase activity
GPY17_RS23090	COG0629	single-stranded DNA binding
GPY17_RS23105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPY17_RS23115	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GPY17_RS23120	COG0527	aspartate kinase activity
GPY17_RS23145	COG3335	DDE superfamily endonuclease
GPY17_RS23210	COG0175	sulfate reduction
GPY17_RS23220	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPY17_RS23245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY17_RS23255	COG0735	belongs to the Fur family
GPY17_RS23265	COG0166	Belongs to the GPI family
GPY17_RS23270	COG0432	Pfam Uncharacterised protein family UPF0047
GPY17_RS23280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY17_RS23285	COG0305	Participates in initiation and elongation during chromosome replication
GPY17_RS23295	COG0359	binds to the 23S rRNA
GPY17_RS23305	COG2965	DNA replication, synthesis of RNA primer
GPY17_RS23310	COG0360	Binds together with S18 to 16S ribosomal RNA
GPY17_RS23315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GPY17_RS23320	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GPY17_RS23330	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPY17_RS23335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GPY17_RS23365	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GPY17_RS23375	COG0678	peroxiredoxin activity
GPY17_RS23375	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPY17_RS23390	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GPY17_RS23390	COG0165	Argininosuccinate lyase
GPY17_RS23395	COG0137	argininosuccinate synthase activity
GPY17_RS23400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GPY17_RS23405	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPY17_RS23410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GPY17_RS23415	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GPY17_RS23425	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GPY17_RS23430	COG0460	homoserine dehydrogenase
GPY17_RS23430	COG0527	aspartate kinase activity
GPY17_RS23435	COG0626	cystathionine gamma-synthase activity
GPY17_RS23445	COG0281	malic enzyme
GPY17_RS23455	COG2906	2 iron, 2 sulfur cluster binding
GPY17_RS23460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPY17_RS23465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPY17_RS23470	COG0049	tRNA binding
GPY17_RS23480	COG2168	tRNA wobble position uridine thiolation
GPY17_RS23485	COG2923	Belongs to the DsrF TusC family
GPY17_RS23490	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GPY17_RS23495	COG2964	Protein conserved in bacteria
GPY17_RS23500	COG0545	Peptidyl-prolyl cis-trans isomerase
GPY17_RS23510	COG2900	Belongs to the SlyX family
GPY17_RS23515	COG1446	asparaginase
GPY17_RS23525	COG1047	Peptidyl-prolyl cis-trans
GPY17_RS23540	COG2249	NAD(P)H dehydrogenase (quinone) activity
GPY17_RS23550	COG0488	(ABC) transporter
GPY17_RS23560	COG0429	hydrolase of the alpha beta-hydrolase fold
GPY17_RS23565	COG3089	Belongs to the UPF0270 family
GPY17_RS23570	COG3954	Phosphoribulokinase
GPY17_RS23575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GPY17_RS23585	COG1012	belongs to the aldehyde dehydrogenase family
GPY17_RS23595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GPY17_RS23600	COG0512	Glutamine amidotransferase of anthranilate synthase
GPY17_RS23630	COG0180	Tryptophanyl-tRNA synthetase
GPY17_RS23635	COG0546	phosphoglycolate phosphatase activity
GPY17_RS23640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPY17_RS23645	COG0557	exoribonuclease II activity
GPY17_RS23650	COG1959	2 iron, 2 sulfur cluster binding
GPY17_RS23655	COG1017	nitric oxide dioxygenase activity
GPY17_RS23655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPY17_RS23660	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GPY17_RS23670	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPY17_RS23675	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GPY17_RS23680	COG0330	HflC and HflK could
GPY17_RS23685	COG0330	HflC and HflK could
GPY17_RS23700	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPY17_RS23705	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPY17_RS23715	COG0802	atpase or kinase
GPY17_RS23720	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPY17_RS23800	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GPY17_RS23805	COG1162	GTPase activity
GPY17_RS23810	COG0688	phosphatidylethanolamine metabolic process
GPY17_RS23815	COG0471	metal ion transport
GPY17_RS23830	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPY17_RS23835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY17_RS23840	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GPY17_RS23845	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GPY17_RS23850	COG1045	serine acetyltransferase
GPY17_RS23855	COG4942	peptidase
GPY17_RS23875	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GPY17_RS23885	COG1053	succinate dehydrogenase
GPY17_RS23890	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GPY17_RS23895	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPY17_RS23900	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GPY17_RS23910	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPY17_RS23915	COG1509	lysine 2,3-aminomutase activity
GPY17_RS23925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPY17_RS23940	COG0459	protein refolding
GPY17_RS23945	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPY17_RS23950	COG0534	Mate efflux family protein
GPY17_RS23955	COG0205	6-phosphofructokinase activity
GPY17_RS23965	COG3678	ATP-independent chaperone mediated protein folding
GPY17_RS23970	COG0745	RESPONSE REGULATOR receiver
GPY17_RS23975	COG2205	protein histidine kinase activity
GPY17_RS23985	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GPY17_RS23990	COG3030	protein affecting phage T7 exclusion by the F plasmid
GPY17_RS23995	COG1027	Aspartate ammonia-lyase
GPY17_RS24000	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GPY17_RS24005	COG4232	protein-disulfide reductase activity
GPY17_RS24015	COG3263	regulation of cellular component size
GPY17_RS24025	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPY17_RS24050	COG0784	Response regulator, receiver
GPY17_RS24050	COG2205	protein histidine kinase activity
GPY17_RS24055	COG2814	Major facilitator Superfamily
GPY17_RS24070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GPY17_RS24075	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GPY17_RS24080	COG0511	ligase activity, forming carbon-carbon bonds
GPY17_RS24085	COG0439	Biotin carboxylase
GPY17_RS24095	COG2264	protein methyltransferase activity
GPY17_RS24100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPY17_RS24105	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GPY17_RS24175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPY17_RS24185	COG2814	Major facilitator Superfamily
GPY17_RS24190	COG0488	(ABC) transporter
GPY17_RS24195	COG3706	GGDEF domain
GPY17_RS24255	COG1982	Orn Lys Arg decarboxylase major
GPY17_RS24260	COG0531	amino acid
GPY17_RS24270	COG3710	Transcriptional regulator
GPY17_RS24275	COG0789	Transcriptional regulator
GPY17_RS24285	COG0138	bifunctional purine biosynthesis protein purh
GPY17_RS24310	COG1253	flavin adenine dinucleotide binding
GPY17_RS24315	COG3068	Protein conserved in bacteria
GPY17_RS24320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GPY17_RS24325	COG1573	uracil-dna glycosylase
GPY17_RS24330	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GPY17_RS24345	COG2816	NAD+ diphosphatase activity
GPY17_RS24350	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GPY17_RS24355	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPY17_RS24360	COG0085	RNA polymerase activity
GPY17_RS24365	COG0222	ribosome binding
GPY17_RS24370	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPY17_RS24375	COG0081	regulation of translation
GPY17_RS24380	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPY17_RS24385	COG0250	Participates in transcription elongation, termination and antitermination
GPY17_RS24390	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GPY17_RS24400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPY17_RS24435	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GPY17_RS24445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPY17_RS24500	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GPY17_RS24510	COG4206	TonB-dependent receptor
GPY17_RS24515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPY17_RS24530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPY17_RS24535	COG0534	Mate efflux family protein
GPY17_RS24540	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GPY17_RS24545	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPY17_RS24555	COG2937	Belongs to the GPAT DAPAT family
GPY17_RS24560	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GPY17_RS24565	COG3161	chorismate lyase activity
GPY17_RS24570	COG1580	Controls the rotational direction of flagella during chemotaxis
GPY17_RS24575	COG0705	Rhomboid family
GPY17_RS24580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPY17_RS24590	COG2177	Part of the ABC transporter FtsEX involved in
GPY17_RS24595	COG2884	Cell division ATP-binding protein ftsE
GPY17_RS24600	COG0552	protein localization to endoplasmic reticulum
GPY17_RS24605	COG0742	ribosomal rna small subunit methyltransferase
GPY17_RS24615	COG2095	MarC family integral membrane protein
GPY17_RS24670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GPY17_RS24675	COG0640	Transcriptional regulator
GPY17_RS24680	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GPY17_RS24685	COG1280	lysine exporter protein (LysE YggA)
GPY17_RS24690	COG2267	carboxylic ester hydrolase activity
GPY17_RS24695	COG0561	phosphatase activity
GPY17_RS24715	COG3287	FIST C domain
GPY17_RS24715	COG2200	EAL domain
GPY17_RS24715	COG2199	diguanylate cyclase activity
GPY17_RS24720	COG1011	Hydrolase