locus-tag	class	description
EHC64_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EHC64_RS00010	COG0592	DNA-directed DNA polymerase activity
EHC64_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EHC64_RS00020	COG0187	DNA topoisomerase II activity
EHC64_RS00040	COG0071	Belongs to the small heat shock protein (HSP20) family
EHC64_RS00045	COG3977	Valine--pyruvate aminotransferase
EHC64_RS00050	COG0366	Alpha amylase catalytic
EHC64_RS00055	COG0751	glycine-tRNA ligase activity
EHC64_RS00060	COG0752	glycyl-tRNA synthetase alpha subunit
EHC64_RS00065	COG2119	membrane
EHC64_RS00075	COG0425	Belongs to the sulfur carrier protein TusA family
EHC64_RS00090	COG0604	alcohol dehydrogenase
EHC64_RS00095	COG0183	Belongs to the thiolase family
EHC64_RS00100	COG1250	3-hydroxyacyl-CoA dehydrogenase
EHC64_RS00100	COG1024	Enoyl-CoA hydratase
EHC64_RS00105	COG1739	Uncharacterized protein family UPF0029
EHC64_RS00110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC64_RS00170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHC64_RS00175	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EHC64_RS00180	COG0352	thiamine-phosphate diphosphorylase activity
EHC64_RS00185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EHC64_RS00190	COG2104	thiamine diphosphate biosynthetic process
EHC64_RS00195	COG2022	thiamine diphosphate biosynthetic process
EHC64_RS00205	COG0006	proline dipeptidase activity
EHC64_RS00205	COG0006	proline dipeptidase activity
EHC64_RS00235	COG3220	belongs to the UPF0276 family
EHC64_RS00245	COG0210	DNA helicase
EHC64_RS00255	COG0405	Gamma-glutamyltransferase
EHC64_RS00260	COG1280	lysine exporter protein (LysE YggA)
EHC64_RS00270	COG2962	Rard protein
EHC64_RS00275	COG0514	ATP-dependent DNA helicase (RecQ)
EHC64_RS00290	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EHC64_RS00295	COG0248	Ppx GppA phosphatase
EHC64_RS00300	COG0513	Belongs to the DEAD box helicase family
EHC64_RS00305	COG3118	belongs to the thioredoxin family
EHC64_RS00310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EHC64_RS00325	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EHC64_RS00330	COG0633	Ferredoxin
EHC64_RS00380	COG3071	HemY protein
EHC64_RS00385	COG2959	enzyme of heme biosynthesis
EHC64_RS00390	COG1587	Uroporphyrinogen-III synthase
EHC64_RS00395	COG0181	hydroxymethylbilane synthase activity
EHC64_RS00400	COG3072	Adenylate cyclase
EHC64_RS00405	COG1965	Belongs to the frataxin family
EHC64_RS00415	COG0019	diaminopimelate decarboxylase activity
EHC64_RS00420	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EHC64_RS00430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EHC64_RS00435	COG1011	Hydrolase
EHC64_RS00440	COG2199	diguanylate cyclase activity
EHC64_RS00440	COG3287	FIST C domain
EHC64_RS00440	COG2200	EAL domain
EHC64_RS00460	COG0561	phosphatase activity
EHC64_RS00465	COG2267	carboxylic ester hydrolase activity
EHC64_RS00470	COG1280	lysine exporter protein (LysE YggA)
EHC64_RS00475	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EHC64_RS00480	COG0640	Transcriptional regulator
EHC64_RS00485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC64_RS00540	COG2095	MarC family integral membrane protein
EHC64_RS00550	COG0742	ribosomal rna small subunit methyltransferase
EHC64_RS00555	COG0552	protein localization to endoplasmic reticulum
EHC64_RS00560	COG2884	Cell division ATP-binding protein ftsE
EHC64_RS00565	COG2177	Part of the ABC transporter FtsEX involved in
EHC64_RS00575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC64_RS00580	COG0705	Rhomboid family
EHC64_RS00585	COG1580	Controls the rotational direction of flagella during chemotaxis
EHC64_RS00590	COG3161	chorismate lyase activity
EHC64_RS00595	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EHC64_RS00600	COG2937	Belongs to the GPAT DAPAT family
EHC64_RS00610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHC64_RS00615	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EHC64_RS00620	COG0534	Mate efflux family protein
EHC64_RS00625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC64_RS00680	COG2003	Belongs to the UPF0758 family
EHC64_RS00695	COG3339	Conserved Protein
EHC64_RS00750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHC64_RS00755	COG4206	TonB-dependent receptor
EHC64_RS00765	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EHC64_RS00830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHC64_RS00840	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EHC64_RS00875	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHC64_RS00885	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EHC64_RS00890	COG0250	Participates in transcription elongation, termination and antitermination
EHC64_RS00895	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EHC64_RS00900	COG0081	regulation of translation
EHC64_RS00905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EHC64_RS00910	COG0222	ribosome binding
EHC64_RS00915	COG0085	RNA polymerase activity
EHC64_RS00920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHC64_RS00925	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EHC64_RS00930	COG2816	NAD+ diphosphatase activity
EHC64_RS00945	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EHC64_RS00950	COG1573	uracil-dna glycosylase
EHC64_RS00955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC64_RS00960	COG3068	Protein conserved in bacteria
EHC64_RS00965	COG1253	flavin adenine dinucleotide binding
EHC64_RS00980	COG0151	Belongs to the GarS family
EHC64_RS00990	COG0138	bifunctional purine biosynthesis protein purh
EHC64_RS01000	COG0789	Transcriptional regulator
EHC64_RS01005	COG3710	Transcriptional regulator
EHC64_RS01015	COG0531	amino acid
EHC64_RS01020	COG1982	Orn Lys Arg decarboxylase major
EHC64_RS01085	COG3706	GGDEF domain
EHC64_RS01090	COG0488	(ABC) transporter
EHC64_RS01100	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EHC64_RS01105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC64_RS01110	COG2264	protein methyltransferase activity
EHC64_RS01120	COG0439	Biotin carboxylase
EHC64_RS01125	COG0511	ligase activity, forming carbon-carbon bonds
EHC64_RS01130	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EHC64_RS01135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC64_RS01150	COG2814	Major facilitator Superfamily
EHC64_RS01155	COG0784	Response regulator, receiver
EHC64_RS01155	COG2198	Histidine kinase
EHC64_RS01155	COG2205	protein histidine kinase activity
EHC64_RS01180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC64_RS01190	COG3263	regulation of cellular component size
EHC64_RS01200	COG4232	protein-disulfide reductase activity
EHC64_RS01205	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EHC64_RS01210	COG1027	Aspartate ammonia-lyase
EHC64_RS01215	COG3030	protein affecting phage T7 exclusion by the F plasmid
EHC64_RS01220	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EHC64_RS01230	COG2205	protein histidine kinase activity
EHC64_RS01235	COG0745	RESPONSE REGULATOR receiver
EHC64_RS01240	COG3678	ATP-independent chaperone mediated protein folding
EHC64_RS01250	COG0205	6-phosphofructokinase activity
EHC64_RS01255	COG0534	Mate efflux family protein
EHC64_RS01260	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHC64_RS01265	COG0459	protein refolding
EHC64_RS01280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC64_RS01290	COG1509	lysine 2,3-aminomutase activity
EHC64_RS01295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHC64_RS01305	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EHC64_RS01310	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EHC64_RS01315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EHC64_RS01320	COG1053	succinate dehydrogenase
EHC64_RS01330	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EHC64_RS01350	COG4942	peptidase
EHC64_RS01355	COG1045	serine acetyltransferase
EHC64_RS01360	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EHC64_RS01365	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EHC64_RS01370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC64_RS01375	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EHC64_RS01390	COG0471	metal ion transport
EHC64_RS01395	COG0688	phosphatidylethanolamine metabolic process
EHC64_RS01400	COG1162	GTPase activity
EHC64_RS01405	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EHC64_RS01475	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EHC64_RS01480	COG0802	atpase or kinase
EHC64_RS01485	COG0860	N-Acetylmuramoyl-L-alanine amidase
EHC64_RS01490	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EHC64_RS01495	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EHC64_RS01505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EHC64_RS01510	COG0330	HflC and HflK could
EHC64_RS01515	COG0330	HflC and HflK could
EHC64_RS01520	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EHC64_RS01525	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EHC64_RS01535	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EHC64_RS01540	COG1017	nitric oxide dioxygenase activity
EHC64_RS01540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC64_RS01545	COG1959	2 iron, 2 sulfur cluster binding
EHC64_RS01550	COG0557	exoribonuclease II activity
EHC64_RS01555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC64_RS01560	COG0546	phosphoglycolate phosphatase activity
EHC64_RS01565	COG0180	Tryptophanyl-tRNA synthetase
EHC64_RS01595	COG0512	Glutamine amidotransferase of anthranilate synthase
EHC64_RS01600	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EHC64_RS01610	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_RS01620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC64_RS01625	COG3954	Phosphoribulokinase
EHC64_RS01630	COG3089	Belongs to the UPF0270 family
EHC64_RS01635	COG0429	hydrolase of the alpha beta-hydrolase fold
EHC64_RS01645	COG0488	(ABC) transporter
EHC64_RS01655	COG2249	NAD(P)H dehydrogenase (quinone) activity
EHC64_RS01670	COG1047	Peptidyl-prolyl cis-trans
EHC64_RS01680	COG1446	asparaginase
EHC64_RS01685	COG2900	Belongs to the SlyX family
EHC64_RS01695	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC64_RS01700	COG2964	Protein conserved in bacteria
EHC64_RS01705	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EHC64_RS01710	COG2923	Belongs to the DsrF TusC family
EHC64_RS01715	COG2168	tRNA wobble position uridine thiolation
EHC64_RS01725	COG0049	tRNA binding
EHC64_RS01730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC64_RS01735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHC64_RS01740	COG2906	2 iron, 2 sulfur cluster binding
EHC64_RS01750	COG0281	malic enzyme
EHC64_RS01760	COG0626	cystathionine gamma-synthase activity
EHC64_RS01765	COG0460	homoserine dehydrogenase
EHC64_RS01765	COG0527	aspartate kinase activity
EHC64_RS01770	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EHC64_RS01780	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EHC64_RS01785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC64_RS01790	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EHC64_RS01795	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EHC64_RS01800	COG0137	argininosuccinate synthase activity
EHC64_RS01805	COG0165	Argininosuccinate lyase
EHC64_RS01805	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EHC64_RS01820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EHC64_RS01820	COG0678	peroxiredoxin activity
EHC64_RS01830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EHC64_RS01860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EHC64_RS01865	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EHC64_RS01875	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EHC64_RS01880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EHC64_RS01885	COG0360	Binds together with S18 to 16S ribosomal RNA
EHC64_RS01890	COG2965	DNA replication, synthesis of RNA primer
EHC64_RS01900	COG0359	binds to the 23S rRNA
EHC64_RS01910	COG0305	Participates in initiation and elongation during chromosome replication
EHC64_RS01915	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC64_RS01925	COG0432	Pfam Uncharacterised protein family UPF0047
EHC64_RS01930	COG0166	Belongs to the GPI family
EHC64_RS01940	COG0735	belongs to the Fur family
EHC64_RS01950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC64_RS01975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EHC64_RS01980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC64_RS01985	COG0175	sulfate reduction
EHC64_RS02055	COG0646	methionine synthase
EHC64_RS02055	COG1410	methionine synthase
EHC64_RS02060	COG0527	aspartate kinase activity
EHC64_RS02065	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EHC64_RS02075	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EHC64_RS02090	COG0629	single-stranded DNA binding
EHC64_RS02160	COG0210	DNA helicase
EHC64_RS02165	COG2200	EAL domain
EHC64_RS02165	COG2199	diguanylate cyclase activity
EHC64_RS02190	COG3267	Type II secretory pathway component ExeA
EHC64_RS02190	COG3409	Peptidoglycan-binding domain 1 protein
EHC64_RS02200	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC64_RS02205	COG1459	type II secretion system
EHC64_RS02250	COG1077	Cell shape determining protein MreB Mrl
EHC64_RS02255	COG1792	Involved in formation and maintenance of cell shape
EHC64_RS02260	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EHC64_RS02265	COG0424	maF-like protein
EHC64_RS02270	COG1530	ribonuclease E activity
EHC64_RS02275	COG3164	Protein of unknown function
EHC64_RS02280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHC64_RS02285	COG0312	modulator of DNA gyrase
EHC64_RS02290	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EHC64_RS02295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EHC64_RS02310	COG0564	pseudouridine synthase activity
EHC64_RS02315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHC64_RS02320	COG3028	Belongs to the UPF0307 family
EHC64_RS02325	COG0312	modulator of DNA gyrase
EHC64_RS02330	COG2239	Acts as a magnesium transporter
EHC64_RS02335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_RS02340	COG1660	Displays ATPase and GTPase activities
EHC64_RS02345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_RS02350	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHC64_RS02360	COG1137	ATPase activity
EHC64_RS02365	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EHC64_RS02375	COG0517	IMP dehydrogenase activity
EHC64_RS02375	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EHC64_RS02385	COG1127	ABC transporter
EHC64_RS02390	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EHC64_RS02395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EHC64_RS02400	COG2854	intermembrane phospholipid transfer
EHC64_RS02410	COG5007	Belongs to the BolA IbaG family
EHC64_RS02415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHC64_RS02420	COG0204	Acyl-transferase
EHC64_RS02425	COG0251	oxidation-reduction process
EHC64_RS02430	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EHC64_RS02435	COG0540	Belongs to the ATCase OTCase family
EHC64_RS02445	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EHC64_RS02450	COG2235	arginine
EHC64_RS02480	COG0525	valine-tRNA ligase activity
EHC64_RS02485	COG2927	DNA polymerase III (CHI subunit)
EHC64_RS02490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHC64_RS02495	COG0795	lipopolysaccharide-transporting ATPase activity
EHC64_RS02500	COG0795	lipopolysaccharide-transporting ATPase activity
EHC64_RS02510	COG4325	translation initiation factor activity
EHC64_RS02515	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_RS02525	COG0726	polysaccharide deacetylase
EHC64_RS02530	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EHC64_RS02535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EHC64_RS02540	COG1447	Phosphotransferase system cellobiose-specific component IIA
EHC64_RS02545	COG1486	melibiose metabolic process
EHC64_RS02550	COG3394	polysaccharide catabolic process
EHC64_RS02560	COG3437	response regulator, receiver
EHC64_RS02610	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_RS02680	COG0741	lytic transglycosylase activity
EHC64_RS02685	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EHC64_RS02695	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EHC64_RS02705	COG2066	Belongs to the glutaminase family
EHC64_RS02710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHC64_RS02715	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EHC64_RS02725	COG1872	DUF167
EHC64_RS02730	COG0762	integral membrane protein
EHC64_RS02735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHC64_RS02740	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EHC64_RS02755	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EHC64_RS02760	COG1678	Uncharacterized ACR, COG1678
EHC64_RS02765	COG0189	ligase activity
EHC64_RS02770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EHC64_RS02775	COG2356	endonuclease I
EHC64_RS02780	COG3091	SprT-like family
EHC64_RS02790	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHC64_RS02800	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHC64_RS02805	COG0583	DNA-binding transcription factor activity
EHC64_RS02810	COG4771	TonB-dependent receptor
EHC64_RS02815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC64_RS02820	COG0126	phosphoglycerate kinase activity
EHC64_RS02825	COG0191	fructose-bisphosphate aldolase activity
EHC64_RS02830	COG0668	transmembrane transport
EHC64_RS02835	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EHC64_RS02845	COG0583	DNA-binding transcription factor activity
EHC64_RS02855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC64_RS02860	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EHC64_RS02865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EHC64_RS02875	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EHC64_RS02885	COG3079	Belongs to the UPF0149 family
EHC64_RS02890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC64_RS02895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC64_RS02910	COG0354	folic acid binding
EHC64_RS02915	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EHC64_RS02925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EHC64_RS02935	COG1595	DNA-templated transcription, initiation
EHC64_RS02940	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EHC64_RS02950	COG3086	response to oxidative stress
EHC64_RS02955	COG0481	GTPase activity
EHC64_RS02960	COG0681	Belongs to the peptidase S26 family
EHC64_RS02965	COG0571	ribonuclease III activity
EHC64_RS02970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EHC64_RS02975	COG1381	Involved in DNA repair and RecF pathway recombination
EHC64_RS02980	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EHC64_RS02985	COG0736	holo-[acyl-carrier-protein] synthase activity
EHC64_RS02995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHC64_RS03005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHC64_RS03010	COG3956	TIGRFAM MazG family protein
EHC64_RS03015	COG0504	CTP synthase activity
EHC64_RS03020	COG0148	phosphopyruvate hydratase activity
EHC64_RS03025	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EHC64_RS03030	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EHC64_RS03035	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EHC64_RS03040	COG0585	pseudouridine synthase activity
EHC64_RS03045	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EHC64_RS03050	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EHC64_RS03065	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EHC64_RS03070	COG0582	viral genome integration into host DNA
EHC64_RS03075	COG3335	DDE superfamily endonuclease
EHC64_RS03110	COG2003	Belongs to the UPF0758 family
EHC64_RS03155	COG3501	Rhs element vgr protein
EHC64_RS03195	COG1546	Belongs to the CinA family
EHC64_RS03200	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EHC64_RS03205	COG2137	regulation of response to DNA damage stimulus
EHC64_RS03210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHC64_RS03215	COG0527	aspartate kinase activity
EHC64_RS03275	COG3630	sodium ion export across plasma membrane
EHC64_RS03280	COG5016	pyruvate
EHC64_RS03280	COG0511	ligase activity, forming carbon-carbon bonds
EHC64_RS03285	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EHC64_RS03290	COG1063	alcohol dehydrogenase
EHC64_RS03295	COG1238	metal cluster binding
EHC64_RS03300	COG0612	Peptidase, M16
EHC64_RS03305	COG2918	glutathione biosynthetic process
EHC64_RS03315	COG1854	S-ribosylhomocysteine lyase activity
EHC64_RS03320	COG4536	flavin adenine dinucleotide binding
EHC64_RS03325	COG4137	Cytochrome C assembly protein
EHC64_RS03330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EHC64_RS03335	COG0228	four-way junction DNA binding
EHC64_RS03340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EHC64_RS03345	COG0336	Belongs to the RNA methyltransferase TrmD family
EHC64_RS03350	COG0335	large ribosomal subunit rRNA binding
EHC64_RS03355	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EHC64_RS03360	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EHC64_RS03365	COG0237	dephospho-CoA kinase activity
EHC64_RS03375	COG1459	type II secretion system
EHC64_RS03380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC64_RS03390	COG0157	Belongs to the NadC ModD family
EHC64_RS03400	COG2186	Transcriptional regulator
EHC64_RS03405	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EHC64_RS03410	COG0508	dehydrogenase complex catalyzes the overall conversion of
EHC64_RS03415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC64_RS03430	COG0288	reversible hydration of carbon dioxide
EHC64_RS03435	COG0659	secondary active sulfate transmembrane transporter activity
EHC64_RS03445	COG1131	(ABC) transporter
EHC64_RS03450	COG0842	Transport permease protein
EHC64_RS03455	COG1560	Kdo2-lipid A biosynthetic process
EHC64_RS03465	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EHC64_RS03470	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EHC64_RS03475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHC64_RS03490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC64_RS03500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EHC64_RS03505	COG1489	DNA binding
EHC64_RS03510	COG1643	Atp-dependent helicase
EHC64_RS03515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EHC64_RS03520	COG1752	Esterase of the alpha-beta hydrolase superfamily
EHC64_RS03525	COG1049	propionate catabolic process, 2-methylcitrate cycle
EHC64_RS03530	COG3112	Uncharacterised protein family (UPF0231)
EHC64_RS03540	COG0004	ammonium transporteR
EHC64_RS03545	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC64_RS03555	COG3842	ATPase activity
EHC64_RS03560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC64_RS03575	COG2971	BadF BadG BcrA BcrD
EHC64_RS03585	COG4608	Belongs to the ABC transporter superfamily
EHC64_RS03590	COG0444	Belongs to the ABC transporter superfamily
EHC64_RS03595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC64_RS03605	COG0747	negative chemotaxis
EHC64_RS03610	COG2205	protein histidine kinase activity
EHC64_RS03610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_RS03610	COG0784	Response regulator, receiver
EHC64_RS03610	COG2198	Histidine kinase
EHC64_RS03615	COG2813	Specifically methylates the guanine in position
EHC64_RS03620	COG0628	permease
EHC64_RS03625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EHC64_RS03630	COG0316	Belongs to the HesB IscA family
EHC64_RS03640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC64_RS03645	COG0739	heme binding
EHC64_RS03650	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHC64_RS03660	COG2027	D-alanyl-D-alanine carboxypeptidase
EHC64_RS03665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EHC64_RS03670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC64_RS03675	COG1534	Rna-binding protein
EHC64_RS03680	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EHC64_RS03685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHC64_RS03690	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EHC64_RS03695	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC64_RS03705	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EHC64_RS03720	COG0779	Required for maturation of 30S ribosomal subunits
EHC64_RS03725	COG0195	Participates in both transcription termination and antitermination
EHC64_RS03730	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EHC64_RS03735	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EHC64_RS03740	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EHC64_RS03745	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EHC64_RS03750	COG1185	polyribonucleotide nucleotidyltransferase activity
EHC64_RS03765	COG0534	Mate efflux family protein
EHC64_RS03790	COG3153	acetyltransferase
EHC64_RS03810	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EHC64_RS03820	COG0084	hydrolase, TatD family'
EHC64_RS03825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC64_RS03830	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EHC64_RS03835	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EHC64_RS03840	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EHC64_RS03845	COG0813	purine-nucleoside phosphorylase activity
EHC64_RS03855	COG0560	Phosphoserine phosphatase
EHC64_RS03865	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EHC64_RS03870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC64_RS03875	COG0583	DNA-binding transcription factor activity
EHC64_RS03885	COG1022	Amp-dependent synthetase and ligase
EHC64_RS03890	COG2169	Transcriptional regulator
EHC64_RS03915	COG4964	Belongs to the GSP D family
EHC64_RS03980	COG0583	DNA-binding transcription factor activity
EHC64_RS03985	COG0531	amino acid
EHC64_RS03990	COG2731	YhcH YjgK YiaL family protein
EHC64_RS03995	COG3250	beta-galactosidase activity
EHC64_RS04000	COG1609	Transcriptional regulator
EHC64_RS04010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EHC64_RS04020	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EHC64_RS04025	COG2017	converts alpha-aldose to the beta-anomer
EHC64_RS04040	COG2211	Major facilitator Superfamily
EHC64_RS04045	COG1609	Transcriptional regulator
EHC64_RS04050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC64_RS04065	COG0598	Magnesium transport protein CorA
EHC64_RS04070	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EHC64_RS04075	COG1349	DNA-binding transcription factor activity
EHC64_RS04080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EHC64_RS04085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EHC64_RS04100	COG2271	Major facilitator Superfamily
EHC64_RS04105	COG0584	glycerophosphoryl diester phosphodiesterase
EHC64_RS04110	COG2171	N-acyltransferase activity
EHC64_RS04115	COG3141	response to X-ray
EHC64_RS04135	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EHC64_RS04140	COG1074	ATP-dependent DNA helicase activity
EHC64_RS04145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EHC64_RS04155	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EHC64_RS04155	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EHC64_RS04165	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EHC64_RS04170	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EHC64_RS04175	COG2166	iron-sulfur cluster assembly
EHC64_RS04180	COG3706	GGDEF domain
EHC64_RS04185	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EHC64_RS04190	COG0693	protein deglycase activity
EHC64_RS04195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHC64_RS04200	COG3248	Nucleoside-binding outer membrane protein
EHC64_RS04220	COG1595	DNA-templated transcription, initiation
EHC64_RS04240	COG3056	Lipoprotein
EHC64_RS04245	COG2813	Specifically methylates the guanine in position
EHC64_RS04250	COG0271	Belongs to the BolA IbaG family
EHC64_RS04255	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC64_RS04260	COG1805	sodium ion transport
EHC64_RS04265	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC64_RS04270	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC64_RS04275	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC64_RS04280	COG2871	sodium ion transport
EHC64_RS04285	COG1477	protein flavinylation
EHC64_RS04300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHC64_RS04305	COG0514	ATP-dependent DNA helicase (RecQ)
EHC64_RS04310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC64_RS04325	COG0733	neurotransmitter:sodium symporter activity
EHC64_RS04345	COG0442	prolyl-tRNA aminoacylation
EHC64_RS04350	COG1720	tRNA m6t6A37 methyltransferase activity
EHC64_RS04355	COG0254	rRNA binding
EHC64_RS04370	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EHC64_RS04375	COG1671	Belongs to the UPF0178 family
EHC64_RS04400	COG3098	single-species biofilm formation
EHC64_RS04405	COG0564	pseudouridine synthase activity
EHC64_RS04415	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EHC64_RS04420	COG0024	Methionine aminopeptidase
EHC64_RS04425	COG0052	Belongs to the universal ribosomal protein uS2 family
EHC64_RS04430	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EHC64_RS04435	COG0528	UMP kinase activity
EHC64_RS04440	COG0233	cytoplasmic translational termination
EHC64_RS04445	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EHC64_RS04450	COG0575	Belongs to the CDS family
EHC64_RS04455	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EHC64_RS04460	COG0750	zinc metalloprotease
EHC64_RS04470	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EHC64_RS04475	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC64_RS04480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC64_RS04485	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC64_RS04490	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC64_RS04495	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHC64_RS04500	COG0587	DNA-directed DNA polymerase activity
EHC64_RS04505	COG0825	malonyl-CoA metabolic process
EHC64_RS04510	COG0037	tRNA processing
EHC64_RS04520	COG0347	Belongs to the P(II) protein family
EHC64_RS04525	COG3021	interspecies interaction between organisms
EHC64_RS04535	COG0741	lytic transglycosylase activity
EHC64_RS04535	COG1388	LysM domain
EHC64_RS04540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHC64_RS04545	COG2226	methyltransferase
EHC64_RS04550	COG0328	RNA-DNA hybrid ribonuclease activity
EHC64_RS04555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EHC64_RS04570	COG1960	acyl-CoA dehydrogenase activity
EHC64_RS04575	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EHC64_RS04580	COG0121	glutamine amidotransferase
EHC64_RS04585	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EHC64_RS04590	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EHC64_RS04595	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EHC64_RS04600	COG2233	PERMEase
EHC64_RS04620	COG1393	Belongs to the ArsC family
EHC64_RS04625	COG4783	chaperone-mediated protein folding
EHC64_RS04640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EHC64_RS04645	COG2716	regulation of RNA biosynthetic process
EHC64_RS04650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHC64_RS04670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC64_RS04675	COG1393	Belongs to the ArsC family
EHC64_RS04705	COG2837	iron assimilation
EHC64_RS04710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_RS04720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_RS04725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_RS04730	COG1334	flagellar protein FlaG
EHC64_RS04735	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHC64_RS04745	COG1516	flagellar protein fliS
EHC64_RS04755	COG4191	Histidine kinase
EHC64_RS04760	COG2204	response regulator
EHC64_RS04765	COG1677	Flagellar hook-basal body complex protein FliE
EHC64_RS04775	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC64_RS04825	COG1987	bacterial-type flagellum assembly
EHC64_RS04830	COG1684	flagellar biosynthetic protein fliR
EHC64_RS04850	COG0455	bacterial-type flagellum organization
EHC64_RS04865	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EHC64_RS04870	COG0643	Histidine kinase
EHC64_RS04870	COG2198	Histidine kinase
EHC64_RS04875	COG2201	protein-glutamate methylesterase activity
EHC64_RS04880	COG1192	Involved in chromosome partitioning
EHC64_RS04890	COG0835	chemotaxis
EHC64_RS04900	COG4133	protoheme IX ABC transporter activity
EHC64_RS04905	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC64_RS04910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC64_RS04915	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC64_RS04920	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EHC64_RS04925	COG1138	Cytochrome C-type biogenesis protein
EHC64_RS04930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EHC64_RS04945	COG2853	Lipoprotein
EHC64_RS04955	COG2067	long-chain fatty acid transport protein
EHC64_RS04970	COG0183	Belongs to the thiolase family
EHC64_RS04975	COG1250	3-hydroxyacyl-CoA dehydrogenase
EHC64_RS04975	COG1024	Enoyl-CoA hydratase
EHC64_RS04990	COG2062	phosphohistidine phosphatase, SixA
EHC64_RS04995	COG2840	Smr protein MutS2
EHC64_RS05000	COG2890	protein-(glutamine-N5) methyltransferase activity
EHC64_RS05005	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EHC64_RS05010	COG2860	membrane
EHC64_RS05020	COG3101	peptidyl-lysine hydroxylation
EHC64_RS05035	COG0431	NADPH-dependent FMN reductase
EHC64_RS05040	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EHC64_RS05040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC64_RS05045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EHC64_RS05050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC64_RS05055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHC64_RS05065	COG0101	tRNA pseudouridine synthase activity
EHC64_RS05070	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHC64_RS05075	COG0285	dihydrofolate synthase activity
EHC64_RS05080	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EHC64_RS05085	COG1286	toxin biosynthetic process
EHC64_RS05090	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EHC64_RS05095	COG0583	DNA-binding transcription factor activity
EHC64_RS05100	COG0745	RESPONSE REGULATOR receiver
EHC64_RS05110	COG2832	Protein of unknown function (DUF454)
EHC64_RS05115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHC64_RS05125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EHC64_RS05130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EHC64_RS05135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EHC64_RS05140	COG0814	amino acid
EHC64_RS05145	COG0251	oxidation-reduction process
EHC64_RS05150	COG3681	Belongs to the UPF0597 family
EHC64_RS05165	COG2261	transglycosylase associated protein
EHC64_RS05170	COG2983	Belongs to the UPF0260 family
EHC64_RS05175	COG0668	transmembrane transport
EHC64_RS05180	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EHC64_RS05185	COG0346	lactoylglutathione lyase activity
EHC64_RS05195	COG1785	Belongs to the alkaline phosphatase family
EHC64_RS05215	COG2226	methyltransferase
EHC64_RS05230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC64_RS05235	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC64_RS05245	COG3139	Protein of unknown function (DUF1315)
EHC64_RS05250	COG0252	asparaginase activity
EHC64_RS05255	COG0616	signal peptide processing
EHC64_RS05260	COG1902	pentaerythritol trinitrate reductase activity
EHC64_RS05260	COG0446	pyridine nucleotide-disulphide oxidoreductase
EHC64_RS05265	COG0778	Nitroreductase
EHC64_RS05270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC64_RS05290	COG0123	including yeast histone deacetylase and acetoin utilization protein
EHC64_RS05300	COG3083	sulfuric ester hydrolase activity
EHC64_RS05305	COG3082	Protein of unknown function (DUF1414)
EHC64_RS05310	COG3081	Nucleoid-associated protein
EHC64_RS05325	COG1757	Na H antiporter
EHC64_RS05330	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHC64_RS05335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC64_RS05340	COG2095	MarC family integral membrane protein
EHC64_RS05345	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_RS05345	COG1454	alcohol dehydrogenase
EHC64_RS05365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EHC64_RS05375	COG2056	Na+-H+ antiporter family
EHC64_RS05380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EHC64_RS05395	COG2885	chlorophyll binding
EHC64_RS05405	COG0346	lactoylglutathione lyase activity
EHC64_RS05410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EHC64_RS05415	COG4660	Part of a membrane complex involved in electron transport
EHC64_RS05420	COG4659	FMN binding
EHC64_RS05425	COG4658	electron transport chain
EHC64_RS05430	COG4656	Part of a membrane complex involved in electron transport
EHC64_RS05435	COG2878	Part of a membrane complex involved in electron transport
EHC64_RS05440	COG4657	Part of a membrane complex involved in electron transport
EHC64_RS05455	COG0556	nucleotide-excision repair
EHC64_RS05460	COG2204	response regulator
EHC64_RS05465	COG2198	Histidine kinase
EHC64_RS05470	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EHC64_RS05475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHC64_RS05480	COG0521	Mo-molybdopterin cofactor biosynthetic process
EHC64_RS05485	COG0315	cyclic pyranopterin monophosphate synthase activity
EHC64_RS05490	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EHC64_RS05495	COG0314	molybdopterin synthase activity
EHC64_RS05505	COG0601	transmembrane transport
EHC64_RS05510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC64_RS05515	COG0444	Belongs to the ABC transporter superfamily
EHC64_RS05525	COG0435	Glutathione S-transferase
EHC64_RS05535	COG3174	membrane
EHC64_RS05540	COG0857	belongs to the CobB CobQ family
EHC64_RS05540	COG0280	phosphate acetyltransferase
EHC64_RS05545	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHC64_RS05550	COG3092	negative regulation of chromosome organization
EHC64_RS05560	COG4120	Belongs to the binding-protein-dependent transport system permease family
EHC64_RS05565	COG1122	ATPase activity
EHC64_RS05570	COG0366	Alpha amylase catalytic
EHC64_RS05575	COG0745	RESPONSE REGULATOR receiver
EHC64_RS05575	COG3706	GGDEF domain
EHC64_RS05580	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC64_RS05585	COG0653	protein targeting
EHC64_RS05590	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EHC64_RS05595	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC64_RS05600	COG2186	Transcriptional regulator
EHC64_RS05610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC64_RS05610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC64_RS05615	COG0489	protein tyrosine kinase activity
EHC64_RS05620	COG0572	uridine kinase
EHC64_RS05630	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EHC64_RS05635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHC64_RS05640	COG0659	secondary active sulfate transmembrane transporter activity
EHC64_RS05645	COG1530	ribonuclease E activity
EHC64_RS05650	COG0564	pseudouridine synthase activity
EHC64_RS05655	COG0424	maF-like protein
EHC64_RS05660	COG1399	metal-binding, possibly nucleic acid-binding protein
EHC64_RS05670	COG0416	fatty acid biosynthetic process
EHC64_RS05675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHC64_RS05705	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHC64_RS05710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EHC64_RS05720	COG0084	hydrolase, TatD family'
EHC64_RS05725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC64_RS05725	COG1263	PTS System
EHC64_RS05745	COG0733	neurotransmitter:sodium symporter activity
EHC64_RS05760	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC64_RS05765	COG0469	pyruvate kinase activity
EHC64_RS05770	COG1940	carbohydrate kinase activity
EHC64_RS05775	COG0784	Response regulator, receiver
EHC64_RS05775	COG0835	chemotaxis
EHC64_RS05780	COG0587	DNA-directed DNA polymerase activity
EHC64_RS05795	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_RS05800	COG0616	signal peptide processing
EHC64_RS05805	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EHC64_RS05810	COG0539	negative regulation of cytoplasmic translation
EHC64_RS05820	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EHC64_RS05825	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EHC64_RS05830	COG0284	orotidine-5'-phosphate decarboxylase activity
EHC64_RS05835	COG4166	transmembrane transport
EHC64_RS05860	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EHC64_RS05870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EHC64_RS05870	COG3008	intermembrane lipid transfer
EHC64_RS05875	COG2995	paraquat-inducible protein a
EHC64_RS05880	COG3258	Cytochrome c
EHC64_RS05885	COG2863	cytochrome
EHC64_RS05925	COG4232	protein-disulfide reductase activity
EHC64_RS05930	COG3118	belongs to the thioredoxin family
EHC64_RS05960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC64_RS05970	COG1136	(ABC) transporter
EHC64_RS05970	COG0577	efflux transmembrane transporter activity
EHC64_RS05975	COG1136	(ABC) transporter
EHC64_RS05975	COG0577	efflux transmembrane transporter activity
EHC64_RS05980	COG0577	efflux transmembrane transporter activity
EHC64_RS05980	COG1136	(ABC) transporter
EHC64_RS05985	COG1335	isochorismatase
EHC64_RS06000	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHC64_RS06030	COG3850	Histidine kinase
EHC64_RS06030	COG5002	protein histidine kinase activity
EHC64_RS06035	COG0745	RESPONSE REGULATOR receiver
EHC64_RS06090	COG0840	transmembrane signaling receptor activity
EHC64_RS06095	COG1032	radical SAM domain protein
EHC64_RS06100	COG4251	negative regulation of phosphorylation
EHC64_RS06100	COG5001	Diguanylate cyclase
EHC64_RS06100	COG2203	Gaf domain
EHC64_RS06100	COG3706	GGDEF domain
EHC64_RS06115	COG0583	DNA-binding transcription factor activity
EHC64_RS06125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHC64_RS06135	COG2350	Protein conserved in bacteria
EHC64_RS06140	COG1607	acyl-coa hydrolase
EHC64_RS06145	COG2917	probably involved in intracellular septation
EHC64_RS06165	COG1301	dicarboxylic acid transport
EHC64_RS06175	COG0318	PFAM AMP-dependent synthetase and ligase
EHC64_RS06180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC64_RS06190	COG0159	tryptophan synthase activity
EHC64_RS06195	COG0133	tryptophan synthase activity
EHC64_RS06200	COG0135	phosphoribosylanthranilate isomerase activity
EHC64_RS06200	COG0134	indole-3-glycerol-phosphate synthase activity
EHC64_RS06205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHC64_RS06210	COG0512	Glutamine amidotransferase of anthranilate synthase
EHC64_RS06215	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHC64_RS06225	COG0613	PHP domain protein
EHC64_RS06230	COG0009	L-threonylcarbamoyladenylate synthase
EHC64_RS06240	COG1187	pseudouridine synthase activity
EHC64_RS06250	COG3099	Belongs to the UPF0263 family
EHC64_RS06255	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHC64_RS06265	COG0417	DNA replication proofreading
EHC64_RS06270	COG2197	response regulator
EHC64_RS06275	COG0322	excinuclease ABC activity
EHC64_RS06315	COG0019	diaminopimelate decarboxylase activity
EHC64_RS06340	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHC64_RS06345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHC64_RS06350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC64_RS06370	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EHC64_RS06380	COG0437	4 iron, 4 sulfur cluster binding
EHC64_RS06385	COG3301	Polysulphide reductase, NrfD
EHC64_RS06390	COG1138	Cytochrome C-type biogenesis protein
EHC64_RS06400	COG4235	cytochrome complex assembly
EHC64_RS06400	COG3088	subunit of a heme lyase
EHC64_RS06410	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC64_RS06435	COG2989	Protein conserved in bacteria
EHC64_RS06440	COG3108	Peptidase M15
EHC64_RS06445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHC64_RS06460	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EHC64_RS06485	COG1846	Transcriptional regulator
EHC64_RS06490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC64_RS06495	COG0840	transmembrane signaling receptor activity
EHC64_RS06515	COG1448	Aminotransferase
EHC64_RS06540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC64_RS06550	COG0017	Asparaginyl-tRNA synthetase
EHC64_RS06555	COG0840	transmembrane signaling receptor activity
EHC64_RS06560	COG0720	synthase
EHC64_RS06570	COG2200	EAL domain
EHC64_RS06575	COG1760	l-serine dehydratase
EHC64_RS06580	COG0814	amino acid
EHC64_RS06585	COG0494	nUDIX hydrolase
EHC64_RS06595	COG2205	protein histidine kinase activity
EHC64_RS06595	COG0784	Response regulator, receiver
EHC64_RS06600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHC64_RS06620	COG3106	COG3106 Predicted ATPase
EHC64_RS06625	COG3768	UPF0283 membrane protein
EHC64_RS06635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC64_RS06755	COG0454	-acetyltransferase
EHC64_RS06975	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHC64_RS07235	COG0625	glutathione transferase activity
EHC64_RS07415	COG2314	TM2 domain
EHC64_RS07495	COG0494	nUDIX hydrolase
EHC64_RS07565	COG1757	Na H antiporter
EHC64_RS07570	COG0174	glutamine synthetase
EHC64_RS07580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EHC64_RS07585	COG1396	sequence-specific DNA binding
EHC64_RS07585	COG1917	Cupin 2, conserved barrel domain protein
EHC64_RS07590	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_RS07595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC64_RS07605	COG2957	Belongs to the agmatine deiminase family
EHC64_RS07610	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_RS07615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHC64_RS07620	COG1227	inorganic diphosphatase activity
EHC64_RS07630	COG2200	EAL domain
EHC64_RS07630	COG2771	luxR family
EHC64_RS07640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHC64_RS07655	COG1846	Transcriptional regulator
EHC64_RS07660	COG2315	Protein conserved in bacteria
EHC64_RS07680	COG0110	maltose O-acetyltransferase activity
EHC64_RS07710	COG3063	Type IV pilus biogenesis stability protein PilW
EHC64_RS07715	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EHC64_RS07730	COG0531	amino acid
EHC64_RS07740	COG1560	Kdo2-lipid A biosynthetic process
EHC64_RS07745	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EHC64_RS07750	COG1280	lysine exporter protein (LysE YggA)
EHC64_RS07760	COG1115	amino acid carrier protein
EHC64_RS07785	COG1368	sulfuric ester hydrolase activity
EHC64_RS07790	COG0642	Histidine kinase
EHC64_RS07795	COG0745	RESPONSE REGULATOR receiver
EHC64_RS07805	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_RS07825	COG2113	Glycine betaine
EHC64_RS07830	COG4176	ABC-type proline glycine betaine transport system permease component
EHC64_RS07850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC64_RS07855	COG0456	acetyltransferase
EHC64_RS07860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHC64_RS07865	COG0662	Cupin 2, conserved barrel domain protein
EHC64_RS07870	COG0527	aspartate kinase activity
EHC64_RS07875	COG1858	cytochrome C peroxidase
EHC64_RS07890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC64_RS07905	COG3290	protein histidine kinase activity
EHC64_RS07910	COG4565	transcriptional regulatory protein
EHC64_RS07920	COG0363	glucosamine-6-phosphate deaminase activity
EHC64_RS07925	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EHC64_RS07945	COG3284	Transcriptional regulator
EHC64_RS07950	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_RS08020	COG4669	(LipO)protein
EHC64_RS08040	COG3177	Filamentation induced by cAMP protein fic
EHC64_RS08080	COG1073	alpha beta
EHC64_RS08085	COG1073	alpha beta
EHC64_RS08095	COG4792	protein secretion
EHC64_RS08100	COG4791	protein targeting
EHC64_RS08105	COG4794	Type iii secretion
EHC64_RS08110	COG4790	Type iii secretion
EHC64_RS08115	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC64_RS08180	COG0457	Tetratricopeptide repeat
EHC64_RS08200	COG0730	response to heat
EHC64_RS08230	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EHC64_RS08235	COG0372	Belongs to the citrate synthase family
EHC64_RS08245	COG2828	Protein conserved in bacteria
EHC64_RS08280	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EHC64_RS08325	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EHC64_RS08330	COG0840	transmembrane signaling receptor activity
EHC64_RS08335	COG1254	Belongs to the acylphosphatase family
EHC64_RS08340	COG2920	part of a sulfur-relay system
EHC64_RS08350	COG0670	Belongs to the BI1 family
EHC64_RS08355	COG1126	abc transporter atp-binding protein
EHC64_RS08360	COG0765	amino acid transport
EHC64_RS08365	COG4597	amino acid ABC transporter
EHC64_RS08370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_RS08390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC64_RS08410	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EHC64_RS08410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHC64_RS08415	COG3008	intermembrane lipid transfer
EHC64_RS08420	COG2995	paraquat-inducible protein a
EHC64_RS08425	COG1132	(ABC) transporter
EHC64_RS08430	COG1956	GAF domain-containing protein
EHC64_RS08435	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EHC64_RS08450	COG0308	aminopeptidase N
EHC64_RS08460	COG2902	Dehydrogenase
EHC64_RS08465	COG0167	dihydroorotate dehydrogenase activity
EHC64_RS08480	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EHC64_RS08480	COG0116	Belongs to the methyltransferase superfamily
EHC64_RS08505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC64_RS08510	COG1067	ATP-dependent peptidase activity
EHC64_RS08515	COG3120	sequence-specific DNA binding
EHC64_RS08565	COG4128	Pfam Zonular occludens toxin
EHC64_RS08630	COG3278	Belongs to the heme-copper respiratory oxidase family
EHC64_RS08645	COG2010	Cytochrome c
EHC64_RS08655	COG2217	Heavy metal translocating P-type atpase
EHC64_RS08670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC64_RS08675	COG0589	response to stress
EHC64_RS08685	COG0037	tRNA processing
EHC64_RS08705	COG3842	ATPase activity
EHC64_RS08710	COG1176	ABC-type spermidine putrescine transport system, permease component I
EHC64_RS08715	COG1177	transmembrane transport
EHC64_RS08720	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC64_RS08730	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EHC64_RS08740	COG0004	ammonium transporteR
EHC64_RS08765	COG0437	4 iron, 4 sulfur cluster binding
EHC64_RS08770	COG0243	molybdopterin cofactor binding
EHC64_RS08770	COG3383	formate dehydrogenase (NAD+) activity
EHC64_RS08780	COG3381	protein complex oligomerization
EHC64_RS08805	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHC64_RS08810	COG0488	(ABC) transporter
EHC64_RS08820	COG4191	Histidine kinase
EHC64_RS08825	COG2204	response regulator
EHC64_RS08845	COG3842	ATPase activity
EHC64_RS08850	COG0746	molybdenum cofactor guanylyltransferase activity
EHC64_RS08855	COG0303	'Molybdopterin
EHC64_RS08865	COG1940	carbohydrate kinase activity
EHC64_RS08905	COG3290	protein histidine kinase activity
EHC64_RS08905	COG0840	transmembrane signaling receptor activity
EHC64_RS08910	COG0791	NLP P60 protein
EHC64_RS08920	COG3706	GGDEF domain
EHC64_RS08925	COG2201	protein-glutamate methylesterase activity
EHC64_RS08940	COG0307	riboflavin synthase, alpha
EHC64_RS08945	COG0534	Mate efflux family protein
EHC64_RS08955	COG1793	dna ligase
EHC64_RS08990	COG2204	response regulator
EHC64_RS09035	COG0438	transferase activity, transferring glycosyl groups
EHC64_RS09040	COG1215	transferase activity, transferring glycosyl groups
EHC64_RS09045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EHC64_RS09055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC64_RS09070	COG1643	Atp-dependent helicase
EHC64_RS09075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHC64_RS09090	COG3302	dmso reductase anchor subunit
EHC64_RS09095	COG0437	4 iron, 4 sulfur cluster binding
EHC64_RS09100	COG0243	molybdopterin cofactor binding
EHC64_RS09140	COG0443	Heat shock 70 kDa protein
EHC64_RS09145	COG0443	Heat shock 70 kDa protein
EHC64_RS09175	COG1132	(ABC) transporter
EHC64_RS09180	COG1132	(ABC) transporter
EHC64_RS09205	COG0814	amino acid
EHC64_RS09220	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EHC64_RS09310	COG1522	sequence-specific DNA binding
EHC64_RS09345	COG0515	serine threonine protein kinase
EHC64_RS09370	COG3501	Rhs element vgr protein
EHC64_RS09385	COG2204	response regulator
EHC64_RS09410	COG0739	heme binding
EHC64_RS09420	COG0861	Integral membrane protein TerC family
EHC64_RS09430	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC64_RS09435	COG1328	CTP reductase activity
EHC64_RS09440	COG1280	lysine exporter protein (LysE YggA)
EHC64_RS09450	COG5001	Diguanylate cyclase
EHC64_RS09450	COG3300	MHYT domain
EHC64_RS09460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_RS09460	COG4191	Histidine kinase
EHC64_RS09465	COG0471	metal ion transport
EHC64_RS09500	COG0583	DNA-binding transcription factor activity
EHC64_RS09505	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EHC64_RS09565	COG0625	glutathione transferase activity
EHC64_RS09575	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EHC64_RS09585	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC64_RS09595	COG0601	transmembrane transport
EHC64_RS09600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC64_RS09605	COG0444	Belongs to the ABC transporter superfamily
EHC64_RS09625	COG3291	Pkd domain containing protein
EHC64_RS09635	COG1177	transmembrane transport
EHC64_RS09640	COG1176	ABC-type spermidine putrescine transport system, permease component I
EHC64_RS09645	COG3842	ATPase activity
EHC64_RS09650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHC64_RS09655	COG2423	ornithine cyclodeaminase activity
EHC64_RS09675	COG3938	Belongs to the proline racemase family
EHC64_RS09705	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EHC64_RS09710	COG1451	nucleotide metabolic process
EHC64_RS09715	COG3475	LICD family
EHC64_RS09720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EHC64_RS09725	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EHC64_RS09745	COG0583	DNA-binding transcription factor activity
EHC64_RS09765	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
EHC64_RS09770	COG4139	cobalamin transport
EHC64_RS09775	COG2988	succinylglutamate desuccinylase activity
EHC64_RS09800	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EHC64_RS09805	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EHC64_RS09810	COG0702	epimerase
EHC64_RS09820	COG2925	Exonuclease
EHC64_RS09825	COG1380	Effector of murein hydrolase LrgA
EHC64_RS09830	COG1346	cytolysis
EHC64_RS09835	COG0295	cytidine deaminase activity
EHC64_RS09840	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EHC64_RS09845	COG0500	methyltransferase
EHC64_RS09855	COG0776	regulation of translation
EHC64_RS09870	COG0072	phenylalanine-tRNA ligase activity
EHC64_RS09870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC64_RS09875	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EHC64_RS09880	COG3706	GGDEF domain
EHC64_RS09910	COG0393	Putative heavy-metal-binding
EHC64_RS09920	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EHC64_RS09930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHC64_RS09945	COG2188	Transcriptional regulator
EHC64_RS09950	COG1228	amidohydrolase
EHC64_RS09955	COG0010	Belongs to the arginase family
EHC64_RS09960	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EHC64_RS09965	COG2986	histidine ammonia-lyase
EHC64_RS09980	COG0247	lactate metabolic process
EHC64_RS09980	COG0277	FAD linked oxidase domain protein
EHC64_RS10015	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EHC64_RS10030	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EHC64_RS10035	COG1643	Atp-dependent helicase
EHC64_RS10040	COG0281	malic enzyme
EHC64_RS10045	COG2949	membrane
EHC64_RS10050	COG0471	metal ion transport
EHC64_RS10055	COG3706	GGDEF domain
EHC64_RS10055	COG0745	RESPONSE REGULATOR receiver
EHC64_RS10075	COG0492	ferredoxin-NADP+ reductase activity
EHC64_RS10080	COG4988	ABC transporter
EHC64_RS10085	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EHC64_RS10090	COG3048	D-serine ammonia-lyase activity
EHC64_RS10095	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EHC64_RS10105	COG4191	Histidine kinase
EHC64_RS10105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_RS10120	COG3070	regulator of competence-specific genes
EHC64_RS10135	COG2431	L-lysine efflux transmembrane transporter activity
EHC64_RS10145	COG0076	glutamate decarboxylase activity
EHC64_RS10150	COG1737	Transcriptional regulator
EHC64_RS10165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EHC64_RS10170	COG2985	domain, Protein
EHC64_RS10170	COG3273	potassium ion transport
EHC64_RS10175	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EHC64_RS10190	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC64_RS10205	COG4181	ATPase activity
EHC64_RS10210	COG0534	Mate efflux family protein
EHC64_RS10215	COG0702	epimerase
EHC64_RS10220	COG3005	denitrification pathway
EHC64_RS10250	COG2814	Major facilitator Superfamily
EHC64_RS10255	COG1187	pseudouridine synthase activity
EHC64_RS10260	COG1061	Type III restriction enzyme res subunit
EHC64_RS10270	COG0745	RESPONSE REGULATOR receiver
EHC64_RS10275	COG2205	protein histidine kinase activity
EHC64_RS10280	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EHC64_RS10310	COG3313	Fe-S protein
EHC64_RS10335	COG0493	'glutamate synthase
EHC64_RS10345	COG0398	Pfam SNARE associated Golgi protein
EHC64_RS10350	COG4134	Bacterial extracellular solute-binding protein
EHC64_RS10355	COG4135	transport system, permease component
EHC64_RS10360	COG4136	ATPase activity
EHC64_RS10365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHC64_RS10380	COG3604	Transcriptional regulator
EHC64_RS10385	COG1151	hydroxylamine reductase activity
EHC64_RS10390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC64_RS10400	COG0564	pseudouridine synthase activity
EHC64_RS10410	COG0733	neurotransmitter:sodium symporter activity
EHC64_RS10420	COG0626	cystathionine gamma-synthase activity
EHC64_RS10425	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EHC64_RS10430	COG5380	lipid catabolic process
EHC64_RS10435	COG2818	Glycosylase
EHC64_RS10450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC64_RS10455	COG1983	PspC domain protein
EHC64_RS10465	COG1842	Phage shock protein A
EHC64_RS10470	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EHC64_RS10480	COG4168	peptide transport system, permease
EHC64_RS10485	COG4171	peptide transport system, permease
EHC64_RS10495	COG4172	Belongs to the ABC transporter superfamily
EHC64_RS10505	COG1227	inorganic diphosphatase activity
EHC64_RS10520	COG0243	molybdopterin cofactor binding
EHC64_RS10525	COG3005	denitrification pathway
EHC64_RS10530	COG4459	periplasmic nitrate reductase
EHC64_RS10535	COG0390	transport system, permease component
EHC64_RS10545	COG2116	formate transmembrane transporter activity
EHC64_RS10570	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EHC64_RS10575	COG1435	thymidine kinase activity
EHC64_RS10580	COG0215	cysteine-tRNA ligase activity
EHC64_RS10585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHC64_RS10590	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC64_RS10595	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EHC64_RS10605	COG3012	SEC-C Motif Domain Protein
EHC64_RS10610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EHC64_RS10610	COG0140	phosphoribosyl-ATP diphosphatase activity
EHC64_RS10615	COG0107	imidazoleglycerol-phosphate synthase activity
EHC64_RS10620	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EHC64_RS10625	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EHC64_RS10630	COG0131	Imidazoleglycerol-phosphate dehydratase
EHC64_RS10630	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EHC64_RS10635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EHC64_RS10640	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EHC64_RS10645	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EHC64_RS10660	COG1757	Na H antiporter
EHC64_RS10670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC64_RS10680	COG0482	sulfurtransferase activity
EHC64_RS10685	COG2915	High frequency lysogenization protein hflD homolog
EHC64_RS10690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EHC64_RS10715	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EHC64_RS10730	COG0300	oxidoreductase activity
EHC64_RS10740	COG0501	Belongs to the peptidase M48B family
EHC64_RS10750	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EHC64_RS10760	COG0156	8-amino-7-oxononanoate synthase activity
EHC64_RS10765	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EHC64_RS10770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EHC64_RS10775	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EHC64_RS10790	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EHC64_RS10795	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EHC64_RS10800	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EHC64_RS10805	COG1674	ftsk spoiiie
EHC64_RS10815	COG0686	Belongs to the AlaDH PNT family
EHC64_RS10825	COG0583	DNA-binding transcription factor activity
EHC64_RS10840	COG3568	Endonuclease Exonuclease Phosphatase
EHC64_RS10870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC64_RS10875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC64_RS10890	COG0840	transmembrane signaling receptor activity
EHC64_RS11005	COG5002	protein histidine kinase activity
EHC64_RS11005	COG0784	Response regulator, receiver
EHC64_RS11015	COG0754	glutathionylspermidine amidase activity
EHC64_RS11025	COG3766	membrane
EHC64_RS11035	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EHC64_RS11040	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EHC64_RS11045	COG2885	chlorophyll binding
EHC64_RS11050	COG0823	Involved in the tonB-independent uptake of proteins
EHC64_RS11065	COG0811	peptide transport
EHC64_RS11070	COG0824	Thioesterase
EHC64_RS11080	COG4890	Cyd operon protein YbgT
EHC64_RS11085	COG1294	oxidase, subunit
EHC64_RS11090	COG1271	oxidase subunit
EHC64_RS11095	COG2255	four-way junction helicase activity
EHC64_RS11100	COG0632	four-way junction helicase activity
EHC64_RS11105	COG0840	transmembrane signaling receptor activity
EHC64_RS11110	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EHC64_RS11115	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EHC64_RS11120	COG1801	Protein of unknown function DUF72
EHC64_RS11125	COG4106	trans-aconitate 2-methyltransferase activity
EHC64_RS11130	COG0500	methyltransferase
EHC64_RS11140	COG0189	ligase activity
EHC64_RS11140	COG4067	protein conserved in archaea
EHC64_RS11160	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EHC64_RS11165	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EHC64_RS11170	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EHC64_RS11175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC64_RS11180	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EHC64_RS11185	COG0745	RESPONSE REGULATOR receiver
EHC64_RS11190	COG3381	protein complex oligomerization
EHC64_RS11195	COG1609	Transcriptional regulator
EHC64_RS11200	COG3070	regulator of competence-specific genes
EHC64_RS11220	COG0297	glycogen (starch) synthase activity
EHC64_RS11225	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC64_RS11230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC64_RS11240	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EHC64_RS11250	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EHC64_RS11255	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EHC64_RS11260	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EHC64_RS11270	COG0542	response to heat
EHC64_RS11275	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EHC64_RS11280	COG1278	Cold shock
EHC64_RS11290	COG1187	pseudouridine synthase activity
EHC64_RS11295	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC64_RS11305	COG1199	ATP-dependent helicase activity
EHC64_RS11310	COG0730	response to heat
EHC64_RS11315	COG3923	Primosomal replication protein n
EHC64_RS11325	COG0708	Exodeoxyribonuclease III
EHC64_RS11340	COG4215	(ABC) transporter
EHC64_RS11370	COG1882	Formate acetyltransferase
EHC64_RS11380	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC64_RS11390	COG3013	Belongs to the UPF0304 family
EHC64_RS11400	COG2766	serine protein kinase
EHC64_RS11405	COG2718	Belongs to the UPF0229 family
EHC64_RS11410	COG2719	SpoVR family
EHC64_RS11415	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EHC64_RS11425	COG1663	tetraacyldisaccharide 4'-kinase activity
EHC64_RS11430	COG1132	(ABC) transporter
EHC64_RS11435	COG0658	competence protein
EHC64_RS11435	COG2333	competence protein COMEC
EHC64_RS11445	COG4591	ABC-type transport system involved in lipoprotein release permease component
EHC64_RS11450	COG1136	(ABC) transporter
EHC64_RS11455	COG4591	ABC-type transport system involved in lipoprotein release permease component
EHC64_RS11465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EHC64_RS11480	COG1252	NADH dehydrogenase
EHC64_RS11490	COG3150	esterase
EHC64_RS11515	COG0537	adenosine 5'-monophosphoramidase activity
EHC64_RS11545	COG0517	IMP dehydrogenase activity
EHC64_RS11545	COG0516	GMP reductase activity
EHC64_RS11555	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EHC64_RS11560	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EHC64_RS11565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC64_RS11575	COG2199	diguanylate cyclase activity
EHC64_RS11590	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EHC64_RS11595	COG1946	Acyl-CoA thioesterase
EHC64_RS11605	COG1522	sequence-specific DNA binding
EHC64_RS11635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC64_RS11685	COG0477	Major facilitator Superfamily
EHC64_RS11690	COG2855	membrane
EHC64_RS11705	COG1441	menaquinone biosynthetic process
EHC64_RS11710	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EHC64_RS11715	COG0596	Alpha beta hydrolase
EHC64_RS11720	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EHC64_RS11725	COG1169	isochorismate synthase
EHC64_RS11730	COG0436	Aminotransferase
EHC64_RS11735	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EHC64_RS11740	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EHC64_RS11755	COG1555	photosystem II stabilization
EHC64_RS11760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC64_RS11765	COG0776	regulation of translation
EHC64_RS11770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EHC64_RS11775	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EHC64_RS11785	COG0544	peptidyl-prolyl cis-trans isomerase activity
EHC64_RS11795	COG2204	response regulator
EHC64_RS11805	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EHC64_RS11810	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EHC64_RS11815	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EHC64_RS11820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EHC64_RS11840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC64_RS11845	COG0569	domain protein
EHC64_RS11850	COG0513	Belongs to the DEAD box helicase family
EHC64_RS11855	COG1253	flavin adenine dinucleotide binding
EHC64_RS11890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHC64_RS11895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHC64_RS11910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC64_RS11915	COG1216	Glycosyl transferase, family 2
EHC64_RS11920	COG2986	histidine ammonia-lyase
EHC64_RS11945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EHC64_RS11950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC64_RS11955	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_RS11975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EHC64_RS11980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC64_RS11985	COG0583	DNA-binding transcription factor activity
EHC64_RS11990	COG2951	lytic endotransglycosylase activity
EHC64_RS11995	COG3100	YcgL domain-containing protein
EHC64_RS12000	COG0850	regulation of cytokinetic process
EHC64_RS12005	COG2894	cell division
EHC64_RS12010	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EHC64_RS12015	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EHC64_RS12020	COG0318	PFAM AMP-dependent synthetase and ligase
EHC64_RS12025	COG2267	carboxylic ester hydrolase activity
EHC64_RS12040	COG1214	PFAM Peptidase M22, glycoprotease
EHC64_RS12045	COG1199	ATP-dependent helicase activity
EHC64_RS12050	COG0788	formyltetrahydrofolate deformylase activity
EHC64_RS12055	COG3102	Protein conserved in bacteria
EHC64_RS12065	COG0018	arginyl-trna synthetase
EHC64_RS12085	COG1918	ferrous iron import across plasma membrane
EHC64_RS12100	COG4977	sequence-specific DNA binding
EHC64_RS12105	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EHC64_RS12110	COG1121	(ABC) transporter
EHC64_RS12115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EHC64_RS12125	COG0045	succinate-CoA ligase (ADP-forming) activity
EHC64_RS12130	COG0508	dehydrogenase complex catalyzes the overall conversion of
EHC64_RS12135	COG0567	Dehydrogenase, E1 component
EHC64_RS12140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EHC64_RS12145	COG1053	succinate dehydrogenase
EHC64_RS12150	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EHC64_RS12155	COG2009	succinate dehydrogenase
EHC64_RS12165	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EHC64_RS12175	COG0033	Phosphoglucomutase
EHC64_RS12180	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EHC64_RS12185	COG0596	Alpha beta hydrolase
EHC64_RS12195	COG0716	FMN binding
EHC64_RS12205	COG0735	belongs to the Fur family
EHC64_RS12210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC64_RS12215	COG2190	(PTS) system
EHC64_RS12215	COG1263	PTS System
EHC64_RS12215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC64_RS12225	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EHC64_RS12230	COG1846	Transcriptional regulator
EHC64_RS12230	COG1940	carbohydrate kinase activity
EHC64_RS12235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EHC64_RS12235	COG4651	solute:proton antiporter activity
EHC64_RS12240	COG0367	asparagine synthase
EHC64_RS12245	COG0250	Participates in transcription elongation, termination and antitermination
EHC64_RS12250	COG3104	oligopeptide transport
EHC64_RS12255	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EHC64_RS12260	COG0563	adenylate kinase activity
EHC64_RS12265	COG0326	Molecular chaperone. Has ATPase activity
EHC64_RS12270	COG3710	Transcriptional regulator
EHC64_RS12290	COG0622	Phosphoesterase
EHC64_RS12320	COG1090	epimerase
EHC64_RS12325	COG0300	oxidoreductase activity
EHC64_RS12335	COG3118	belongs to the thioredoxin family
EHC64_RS12340	COG0330	HflC and HflK could
EHC64_RS12365	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHC64_RS12370	COG3115	cell septum assembly
EHC64_RS12375	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EHC64_RS12380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EHC64_RS12390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_RS12395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHC64_RS12400	COG2190	(PTS) system
EHC64_RS12410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_RS12415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_RS12425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_RS12435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_RS12445	COG1705	Flagellar rod assembly protein muramidase FlgJ
EHC64_RS12445	COG3951	Flagellar rod assembly protein muramidase FlgJ
EHC64_RS12450	COG1706	bacterial-type flagellum-dependent cell motility
EHC64_RS12455	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EHC64_RS12460	COG4786	Flagellar basal body rod
EHC64_RS12465	COG4787	bacterial-type flagellum-dependent cell motility
EHC64_RS12475	COG1749	Flagellar hook protein flgE
EHC64_RS12480	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EHC64_RS12485	COG1558	bacterial-type flagellum-dependent cell motility
EHC64_RS12490	COG1815	bacterial-type flagellum-dependent cell motility
EHC64_RS12495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EHC64_RS12500	COG0784	Response regulator, receiver
EHC64_RS12500	COG0835	chemotaxis
EHC64_RS12560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC64_RS12565	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC64_RS12580	COG2217	Heavy metal translocating P-type atpase
EHC64_RS12580	COG2608	mercury ion transmembrane transporter activity
EHC64_RS12620	COG2840	Smr protein MutS2
EHC64_RS12625	COG1187	pseudouridine synthase activity
EHC64_RS12635	COG0737	Belongs to the 5'-nucleotidase family
EHC64_RS12640	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EHC64_RS12645	COG2912	Transglutaminase-like superfamily
EHC64_RS12650	COG3094	Invasion gene expression up-regulator, SirB
EHC64_RS12655	COG2890	protein-(glutamine-N5) methyltransferase activity
EHC64_RS12660	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EHC64_RS12665	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EHC64_RS12670	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EHC64_RS12675	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EHC64_RS12680	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EHC64_RS12685	COG0193	aminoacyl-tRNA hydrolase activity
EHC64_RS12690	COG0012	GTP binding
EHC64_RS12805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC64_RS12815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHC64_RS12820	COG1702	phosphate starvation-inducible protein PhoH
EHC64_RS12825	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EHC64_RS12830	COG4535	Mg2 and Co2 transporter CorC
EHC64_RS12835	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EHC64_RS12840	COG2888	peptidyl-tyrosine sulfation
EHC64_RS12845	COG0495	leucyl-tRNA aminoacylation
EHC64_RS12850	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EHC64_RS12855	COG1466	dna polymerase III delta subunit
EHC64_RS12860	COG0799	negative regulation of ribosome biogenesis
EHC64_RS12865	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EHC64_RS12870	COG0768	penicillin binding
EHC64_RS12875	COG0772	Belongs to the SEDS family
EHC64_RS12880	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EHC64_RS12885	COG1686	Belongs to the peptidase S11 family
EHC64_RS12890	COG2921	Belongs to the UPF0250 family
EHC64_RS12895	COG0321	lipoyl(octanoyl) transferase activity
EHC64_RS12900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EHC64_RS12905	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHC64_RS12910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHC64_RS12925	COG0366	Alpha amylase catalytic
EHC64_RS12930	COG1263	PTS System
EHC64_RS12930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC64_RS12940	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EHC64_RS12950	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EHC64_RS12955	COG2011	ABC-type metal ion transport system permease component
EHC64_RS12960	COG1464	Belongs to the NlpA lipoprotein family
EHC64_RS12965	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
EHC64_RS12975	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHC64_RS12975	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHC64_RS12985	COG3706	GGDEF domain
EHC64_RS12985	COG0745	RESPONSE REGULATOR receiver
EHC64_RS12990	COG1611	Belongs to the LOG family
EHC64_RS12995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC64_RS13005	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EHC64_RS13010	COG2363	Small membrane protein
EHC64_RS13020	COG0583	DNA-binding transcription factor activity
EHC64_RS13025	COG0301	tRNA thio-modification
EHC64_RS13025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC64_RS13030	COG2885	chlorophyll binding
EHC64_RS13035	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EHC64_RS13040	COG1722	exodeoxyribonuclease VII activity
EHC64_RS13045	COG0142	geranyltranstransferase activity
EHC64_RS13050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EHC64_RS13055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EHC64_RS13060	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EHC64_RS13065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHC64_RS13085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC64_RS13085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC64_RS13090	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EHC64_RS13095	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EHC64_RS13100	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHC64_RS13115	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EHC64_RS13120	COG2252	PERMEase
EHC64_RS13125	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC64_RS13150	COG0047	phosphoribosylformylglycinamidine synthase activity
EHC64_RS13150	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHC64_RS13155	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EHC64_RS13165	COG0590	tRNA wobble adenosine to inosine editing
EHC64_RS13170	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EHC64_RS13210	COG0484	heat shock protein binding
EHC64_RS13215	COG0443	Heat shock 70 kDa protein
EHC64_RS13225	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EHC64_RS13230	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHC64_RS13240	COG0497	DNA recombination
EHC64_RS13245	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC64_RS13250	COG2914	Belongs to the UPF0125 (RnfH) family
EHC64_RS13255	COG2867	negative regulation of translational initiation
EHC64_RS13260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EHC64_RS13270	COG0582	viral genome integration into host DNA
EHC64_RS13285	COG0270	DNA (cytosine-5-)-methyltransferase activity
EHC64_RS13320	COG1278	Cold shock
EHC64_RS13330	COG1278	Cold shock
EHC64_RS13425	COG0583	DNA-binding transcription factor activity
EHC64_RS13430	COG3153	acetyltransferase
EHC64_RS13430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHC64_RS13450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EHC64_RS13455	COG2873	o-acetylhomoserine
EHC64_RS13490	COG1115	amino acid carrier protein
EHC64_RS13500	COG1584	GPR1 FUN34 yaaH family protein
EHC64_RS13510	COG1757	Na H antiporter
EHC64_RS13515	COG0519	Catalyzes the synthesis of GMP from XMP
EHC64_RS13515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EHC64_RS13520	COG0516	GMP reductase activity
EHC64_RS13520	COG0517	IMP dehydrogenase activity
EHC64_RS13525	COG1570	exodeoxyribonuclease VII activity
EHC64_RS13540	COG1160	GTP binding
EHC64_RS13545	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC64_RS13550	COG2976	Protein conserved in bacteria
EHC64_RS13555	COG0124	histidyl-tRNA synthetase
EHC64_RS13560	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EHC64_RS13575	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EHC64_RS13580	COG0105	UTP biosynthetic process
EHC64_RS13585	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHC64_RS13590	COG2975	iron-sulfur cluster assembly
EHC64_RS13595	COG0633	Ferredoxin
EHC64_RS13600	COG0443	Heat shock 70 kDa protein
EHC64_RS13605	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EHC64_RS13615	COG0822	iron-sulfur transferase activity
EHC64_RS13620	COG1104	cysteine desulfurase activity
EHC64_RS13635	COG0483	inositol monophosphate 1-phosphatase activity
EHC64_RS13645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC64_RS13650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC64_RS13655	COG1862	Preprotein translocase
EHC64_RS13660	COG0343	queuine tRNA-ribosyltransferase activity
EHC64_RS13665	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EHC64_RS13675	COG0517	IMP dehydrogenase activity
EHC64_RS13685	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EHC64_RS13695	COG0583	DNA-binding transcription factor activity
EHC64_RS13700	COG0450	alkyl hydroperoxide reductase
EHC64_RS13705	COG3142	Participates in the control of copper homeostasis
EHC64_RS13715	COG0704	Plays a role in the regulation of phosphate uptake
EHC64_RS13720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EHC64_RS13725	COG0581	inorganic phosphate transmembrane transporter activity
EHC64_RS13735	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EHC64_RS13740	COG0248	Ppx GppA phosphatase
EHC64_RS13750	COG5002	protein histidine kinase activity
EHC64_RS13755	COG0745	RESPONSE REGULATOR receiver
EHC64_RS13760	COG2974	May be involved in recombination
EHC64_RS13770	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EHC64_RS13830	COG0542	response to heat
EHC64_RS13840	COG0564	pseudouridine synthase activity
EHC64_RS13845	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC64_RS13850	COG0741	lytic transglycosylase activity
EHC64_RS13855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHC64_RS13860	COG1605	Chorismate mutase
EHC64_RS13860	COG0077	Prephenate dehydratase
EHC64_RS13865	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EHC64_RS13870	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EHC64_RS13880	COG0488	(ABC) transporter
EHC64_RS13895	COG0739	heme binding
EHC64_RS13900	COG0287	Prephenate dehydrogenase
EHC64_RS13900	COG1605	Chorismate mutase
EHC64_RS13905	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC64_RS13910	COG1472	Belongs to the glycosyl hydrolase 3 family
EHC64_RS13915	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EHC64_RS13920	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHC64_RS13935	COG1966	Carbon starvation protein
EHC64_RS13940	COG3275	phosphorelay sensor kinase activity
EHC64_RS13945	COG3279	Response regulator of the LytR AlgR family
EHC64_RS13950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EHC64_RS13955	COG1047	Peptidyl-prolyl cis-trans
EHC64_RS13960	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EHC64_RS13965	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHC64_RS13970	COG0196	riboflavin kinase activity
EHC64_RS13975	COG0728	peptidoglycan biosynthetic process
EHC64_RS13980	COG0268	Binds directly to 16S ribosomal RNA
EHC64_RS13990	COG0640	Transcriptional regulator
EHC64_RS14000	COG0583	DNA-binding transcription factor activity
EHC64_RS14005	COG1283	sodium-dependent phosphate transmembrane transporter activity
EHC64_RS14015	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EHC64_RS14020	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EHC64_RS14025	COG0730	response to heat
EHC64_RS14035	COG0494	nUDIX hydrolase
EHC64_RS14045	COG3066	DNA modification
EHC64_RS14055	COG0667	Aldo Keto reductase
EHC64_RS14070	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EHC64_RS14080	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EHC64_RS14085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC64_RS14095	COG0716	FMN binding
EHC64_RS14105	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EHC64_RS14110	COG0513	Belongs to the DEAD box helicase family
EHC64_RS14115	COG3022	response to hydroperoxide
EHC64_RS14120	COG1115	amino acid carrier protein
EHC64_RS14135	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EHC64_RS14145	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EHC64_RS14150	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
EHC64_RS14155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EHC64_RS14160	COG0083	homoserine kinase activity
EHC64_RS14175	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EHC64_RS14190	COG0745	RESPONSE REGULATOR receiver
EHC64_RS14200	COG2198	Histidine kinase
EHC64_RS14200	COG5002	protein histidine kinase activity
EHC64_RS14200	COG0784	Response regulator, receiver
EHC64_RS14205	COG4251	negative regulation of phosphorylation
EHC64_RS14205	COG2203	Gaf domain
EHC64_RS14205	COG5001	Diguanylate cyclase
EHC64_RS14205	COG3706	GGDEF domain
EHC64_RS14210	COG1242	4 iron, 4 sulfur cluster binding
EHC64_RS14215	COG0070	glutamate synthase
EHC64_RS14215	COG0067	glutamate synthase
EHC64_RS14215	COG0069	glutamate synthase activity
EHC64_RS14225	COG0069	glutamate synthase activity
EHC64_RS14225	COG0067	glutamate synthase
EHC64_RS14225	COG0070	glutamate synthase
EHC64_RS14230	COG0493	'glutamate synthase
EHC64_RS14240	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHC64_RS14250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHC64_RS14255	COG2860	membrane
EHC64_RS14260	COG0583	DNA-binding transcription factor activity
EHC64_RS14265	COG0730	response to heat
EHC64_RS14280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EHC64_RS14285	COG0505	Belongs to the CarA family
EHC64_RS14290	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EHC64_RS14295	COG0494	nUDIX hydrolase
EHC64_RS14300	COG0653	protein targeting
EHC64_RS14310	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EHC64_RS14315	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EHC64_RS14320	COG0849	cell division
EHC64_RS14325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EHC64_RS14330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EHC64_RS14335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHC64_RS14340	COG0772	Belongs to the SEDS family
EHC64_RS14345	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EHC64_RS14350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EHC64_RS14355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EHC64_RS14360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EHC64_RS14365	COG0768	penicillin binding
EHC64_RS14370	COG3116	cell division
EHC64_RS14375	COG0275	rRNA processing
EHC64_RS14390	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EHC64_RS14400	COG0792	nuclease activity
EHC64_RS14405	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EHC64_RS14410	COG2823	Periplasmic or secreted lipoprotein
EHC64_RS14415	COG2969	positive regulation of protein catabolic process
EHC64_RS14420	COG0625	glutathione transferase activity
EHC64_RS14425	COG2857	Cytochrome c1
EHC64_RS14430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EHC64_RS14435	COG0723	plastoquinol--plastocyanin reductase activity
EHC64_RS14440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EHC64_RS14445	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EHC64_RS14455	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EHC64_RS14465	COG3105	Protein conserved in bacteria
EHC64_RS14475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHC64_RS14480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHC64_RS14485	COG0187	DNA topoisomerase II activity
EHC64_RS14490	COG3150	esterase
EHC64_RS14500	COG3151	Protein conserved in bacteria
EHC64_RS14505	COG0494	nUDIX hydrolase
EHC64_RS14510	COG1538	Outer membrane efflux protein
EHC64_RS14515	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EHC64_RS14515	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EHC64_RS14520	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EHC64_RS14535	COG3025	triphosphatase activity
EHC64_RS14540	COG1392	Phosphate transport regulator
EHC64_RS14545	COG0306	phosphate transporter
EHC64_RS14550	COG4991	sh3 domain protein
EHC64_RS14560	COG3409	Peptidoglycan-binding domain 1 protein
EHC64_RS14560	COG3267	Type II secretory pathway component ExeA
EHC64_RS14565	COG0617	tRNA 3'-terminal CCA addition
EHC64_RS14570	COG1968	undecaprenyl-diphosphatase activity
EHC64_RS14575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHC64_RS14580	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EHC64_RS14585	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EHC64_RS14590	COG0596	Alpha beta hydrolase
EHC64_RS14595	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EHC64_RS14600	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EHC64_RS14605	COG1610	YqeY-like protein
EHC64_RS14610	COG0358	DNA primase activity
EHC64_RS14615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHC64_RS14675	COG0582	viral genome integration into host DNA
EHC64_RS14750	COG0582	viral genome integration into host DNA
EHC64_RS14755	COG0326	Molecular chaperone. Has ATPase activity
EHC64_RS14775	COG2003	Belongs to the UPF0758 family
EHC64_RS14800	COG1464	Belongs to the NlpA lipoprotein family
EHC64_RS14835	COG2213	PTS system mannitol-specific
EHC64_RS14835	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_RS14840	COG0246	Mannitol dehydrogenase
EHC64_RS14845	COG3722	fumarate hydratase activity
EHC64_RS14860	COG1461	Dihydroxyacetone kinase
EHC64_RS14865	COG2376	Dihydroxyacetone kinase
EHC64_RS14875	COG5002	protein histidine kinase activity
EHC64_RS14890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EHC64_RS14895	COG1349	DNA-binding transcription factor activity
EHC64_RS14905	COG0469	pyruvate kinase activity
EHC64_RS14915	COG3706	GGDEF domain
EHC64_RS14920	COG0440	acetolactate synthase activity
EHC64_RS14925	COG0028	Belongs to the TPP enzyme family
EHC64_RS14930	COG1022	Amp-dependent synthetase and ligase
EHC64_RS14935	COG0583	DNA-binding transcription factor activity
EHC64_RS14955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHC64_RS14960	COG0473	3-isopropylmalate dehydrogenase activity
EHC64_RS14965	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHC64_RS14970	COG0066	3-isopropylmalate dehydratase activity
EHC64_RS14980	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EHC64_RS14985	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EHC64_RS14990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC64_RS14995	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EHC64_RS15000	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EHC64_RS15005	COG2967	ApaG domain
EHC64_RS15010	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EHC64_RS15025	COG2966	Psort location CytoplasmicMembrane, score
EHC64_RS15030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EHC64_RS15040	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EHC64_RS15045	COG0142	geranyltranstransferase activity
EHC64_RS15055	COG0039	L-malate dehydrogenase activity
EHC64_RS15090	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EHC64_RS15095	COG1178	ABC-type Fe3 transport system permease component
EHC64_RS15100	COG4143	(ABC) transporter
EHC64_RS15105	COG0163	prenyltransferase activity
EHC64_RS15110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EHC64_RS15120	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EHC64_RS15125	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EHC64_RS15135	COG2105	PFAM AIG2 family protein
EHC64_RS15145	COG0729	surface antigen
EHC64_RS15150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC64_RS15160	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EHC64_RS15175	COG4181	ATPase activity
EHC64_RS15195	COG0529	Catalyzes the synthesis of activated sulfate
EHC64_RS15200	COG3273	potassium ion transport
EHC64_RS15200	COG0471	metal ion transport
EHC64_RS15210	COG2895	sulfate adenylyltransferase (ATP) activity
EHC64_RS15215	COG0175	sulfate reduction
EHC64_RS15220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EHC64_RS15220	COG1648	precorrin-2 dehydrogenase activity
EHC64_RS15225	COG0737	Belongs to the 5'-nucleotidase family
EHC64_RS15235	COG0513	Belongs to the DEAD box helicase family
EHC64_RS15240	COG2153	protein acetylation
EHC64_RS15250	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC64_RS15260	COG0203	ribosomal protein L17
EHC64_RS15265	COG0202	RNA polymerase activity
EHC64_RS15275	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EHC64_RS15280	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EHC64_RS15290	COG0201	protein transport
EHC64_RS15295	COG0200	Binds to the 23S rRNA
EHC64_RS15300	COG1841	ribosomal large subunit assembly
EHC64_RS15315	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EHC64_RS15320	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EHC64_RS15325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHC64_RS15330	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EHC64_RS15335	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EHC64_RS15340	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EHC64_RS15345	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EHC64_RS15350	COG0255	Belongs to the universal ribosomal protein uL29 family
EHC64_RS15360	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EHC64_RS15365	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EHC64_RS15370	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EHC64_RS15375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EHC64_RS15385	COG0088	Forms part of the polypeptide exit tunnel
EHC64_RS15390	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EHC64_RS15400	COG0254	rRNA binding
EHC64_RS15410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHC64_RS15415	COG1609	Transcriptional regulator
EHC64_RS15425	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EHC64_RS15430	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EHC64_RS15435	COG1575	Belongs to the MenA family. Type 1 subfamily
EHC64_RS15440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EHC64_RS15445	COG3074	FtsZ-dependent cytokinesis
EHC64_RS15455	COG1494	fructose-1,6-bisphosphatase
EHC64_RS15480	COG0149	triose-phosphate isomerase activity
EHC64_RS15505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EHC64_RS15515	COG0438	transferase activity, transferring glycosyl groups
EHC64_RS15540	COG0438	transferase activity, transferring glycosyl groups
EHC64_RS15600	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC64_RS15610	COG1560	Kdo2-lipid A biosynthetic process
EHC64_RS15615	COG0859	PFAM glycosyl transferase family 9
EHC64_RS15620	COG1519	Transferase
EHC64_RS15640	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_RS15650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EHC64_RS15665	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC64_RS15675	COG2089	acid synthase
EHC64_RS15680	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EHC64_RS15685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EHC64_RS15695	COG3642	lipopolysaccharide core region biosynthetic process
EHC64_RS15700	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EHC64_RS15705	COG0859	PFAM glycosyl transferase family 9
EHC64_RS15710	COG0463	Glycosyl transferase, family 2
EHC64_RS15725	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EHC64_RS15730	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EHC64_RS15740	COG2194	sulfuric ester hydrolase activity
EHC64_RS15750	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EHC64_RS15755	COG2003	Belongs to the UPF0758 family
EHC64_RS15770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EHC64_RS15775	COG1309	transcriptional regulator
EHC64_RS15780	COG1560	Kdo2-lipid A biosynthetic process
EHC64_RS15785	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EHC64_RS15790	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EHC64_RS15795	COG1561	YicC-like family, N-terminal region
EHC64_RS15805	COG4608	Belongs to the ABC transporter superfamily
EHC64_RS15810	COG0444	Belongs to the ABC transporter superfamily
EHC64_RS15815	COG0747	negative chemotaxis
EHC64_RS15820	COG4239	(ABC) transporter, permease
EHC64_RS15825	COG4174	ABC transporter (Permease)
EHC64_RS15850	COG0811	peptide transport
EHC64_RS15855	COG0848	biopolymer transport protein
EHC64_RS15870	COG0194	GDP metabolic process
EHC64_RS15875	COG1758	RNA polymerase activity
EHC64_RS15880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHC64_RS15885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC64_RS15890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EHC64_RS15895	COG2233	PERMEase
EHC64_RS15900	COG2205	protein histidine kinase activity
EHC64_RS15905	COG0745	RESPONSE REGULATOR receiver
EHC64_RS15915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC64_RS15925	COG2183	response to ionizing radiation
EHC64_RS15935	COG0596	Alpha beta hydrolase
EHC64_RS15940	COG1040	competence protein
EHC64_RS15945	COG0316	Belongs to the HesB IscA family
EHC64_RS15945	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EHC64_RS15950	COG0494	nUDIX hydrolase
EHC64_RS15955	COG1218	3'(2'),5'-bisphosphate nucleotidase
EHC64_RS15965	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EHC64_RS15970	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EHC64_RS15975	COG3156	type II secretion system protein K
EHC64_RS15980	COG4795	General secretion pathway protein
EHC64_RS15985	COG2165	general secretion pathway protein
EHC64_RS15990	COG2165	general secretion pathway protein
EHC64_RS15995	COG2165	general secretion pathway protein
EHC64_RS16000	COG1459	type II secretion system
EHC64_RS16005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC64_RS16015	COG3031	protein transport across the cell outer membrane
EHC64_RS16020	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EHC64_RS16025	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EHC64_RS16030	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EHC64_RS16040	COG0456	acetyltransferase
EHC64_RS16045	COG1490	D-aminoacyl-tRNA deacylase activity
EHC64_RS16050	COG1295	ribonuclease BN
EHC64_RS16070	COG0174	glutamine synthetase
EHC64_RS16080	COG3852	Histidine kinase
EHC64_RS16085	COG2204	response regulator
EHC64_RS16095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHC64_RS16100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHC64_RS16135	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EHC64_RS16145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC64_RS16145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC64_RS16170	COG0084	hydrolase, TatD family'
EHC64_RS16180	COG0805	protein transport
EHC64_RS16190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHC64_RS16195	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EHC64_RS16200	COG3165	ubiquinone biosynthetic process from chorismate
EHC64_RS16205	COG2226	methyltransferase
EHC64_RS16210	COG1322	Protein conserved in bacteria
EHC64_RS16225	COG0628	permease
EHC64_RS16275	COG2823	Periplasmic or secreted lipoprotein
EHC64_RS16285	COG2081	HI0933 family
EHC64_RS16295	COG1528	Iron-storage protein
EHC64_RS16300	COG0589	response to stress
EHC64_RS16305	COG0697	spore germination
EHC64_RS16315	COG0742	ribosomal rna small subunit methyltransferase
EHC64_RS16320	COG5002	protein histidine kinase activity
EHC64_RS16320	COG5001	Diguanylate cyclase
EHC64_RS16325	COG1522	sequence-specific DNA binding
EHC64_RS16330	COG0339	signal peptide processing
EHC64_RS16335	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EHC64_RS16340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC64_RS16345	COG0583	DNA-binding transcription factor activity
EHC64_RS16350	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EHC64_RS16355	COG0800	Aldolase
EHC64_RS16360	COG2610	gluconate transmembrane transporter activity
EHC64_RS16365	COG3265	gluconokinase activity
EHC64_RS16370	COG0129	dihydroxy-acid dehydratase activity
EHC64_RS16375	COG2076	Multidrug Resistance protein
EHC64_RS16385	COG0583	DNA-binding transcription factor activity
EHC64_RS16390	COG1609	Transcriptional regulator
EHC64_RS16430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC64_RS16440	COG0747	negative chemotaxis
EHC64_RS16445	COG4172	Belongs to the ABC transporter superfamily
EHC64_RS16510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC64_RS16515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC64_RS16525	COG2960	long-chain fatty acid transporting porin activity
EHC64_RS16530	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EHC64_RS16535	COG0583	DNA-binding transcription factor activity
EHC64_RS16575	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EHC64_RS16585	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHC64_RS16590	COG0408	coproporphyrinogen oxidase activity
EHC64_RS16595	COG0009	L-threonylcarbamoyladenylate synthase
EHC64_RS16600	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EHC64_RS16605	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EHC64_RS16610	COG0551	DNA topoisomerase type I activity
EHC64_RS16615	COG2922	Belongs to the Smg family
EHC64_RS16620	COG0758	DNA mediated transformation
EHC64_RS16630	COG0242	peptide deformylase activity
EHC64_RS16635	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EHC64_RS16640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHC64_RS16640	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHC64_RS16645	COG0569	domain protein
EHC64_RS16650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC64_RS16660	COG1272	protein, Hemolysin III
EHC64_RS16665	COG4326	sporulation control protein
EHC64_RS16675	COG3084	Protein conserved in bacteria
EHC64_RS16685	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EHC64_RS16690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC64_RS16695	COG0204	Acyl-transferase
EHC64_RS16790	COG0606	chelatase, subunit chli
EHC64_RS16800	COG3978	acetolactate synthase activity
EHC64_RS16805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EHC64_RS16810	COG0129	dihydroxy-acid dehydratase activity
EHC64_RS16820	COG0583	DNA-binding transcription factor activity
EHC64_RS16825	COG2814	Major facilitator Superfamily
EHC64_RS16830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_RS16835	COG0765	amino acid transport
EHC64_RS16840	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EHC64_RS16845	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EHC64_RS16850	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EHC64_RS16855	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EHC64_RS16860	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EHC64_RS16865	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHC64_RS16880	COG0356	it plays a direct role in the translocation of protons across the membrane
EHC64_RS16885	COG3312	ion transport
EHC64_RS16890	COG1475	DNA binding
EHC64_RS16895	COG1192	Involved in chromosome partitioning
EHC64_RS16900	COG0357	Ribosomal RNA small subunit methyltransferase G
EHC64_RS16905	COG0445	tRNA wobble uridine modification
EHC64_RS16910	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EHC64_RS16915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EHC64_RS16920	COG0706	membrane insertase activity
EHC64_RS16925	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EHC64_RS16930	COG0594	ribonuclease P activity
EHC64_RS16940	COG1126	abc transporter atp-binding protein
EHC64_RS16965	COG2304	oxidoreductase activity
EHC64_RS16980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EHC64_RS16985	COG0581	inorganic phosphate transmembrane transporter activity
EHC64_RS16990	COG0573	inorganic phosphate transmembrane transporter activity
EHC64_RS16995	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EHC64_RS17020	COG4771	TonB-dependent receptor
EHC64_RS17025	COG1770	oligopeptidase
EHC64_RS17030	COG0513	Belongs to the DEAD box helicase family
EHC64_RS17040	COG1388	LysM domain
EHC64_RS17040	COG1376	ErfK ybiS ycfS ynhG family protein
EHC64_RS17045	COG0415	Belongs to the DNA photolyase family
EHC64_RS17050	COG0789	Transcriptional regulator
EHC64_RS17055	COG3272	Protein of unknown function (DUF1722)
EHC64_RS17065	COG0813	purine-nucleoside phosphorylase activity
EHC64_RS17080	COG3706	GGDEF domain
EHC64_RS17090	COG1566	PFAM secretion protein HlyD family protein
EHC64_RS17095	COG4720	Psort location CytoplasmicMembrane, score
EHC64_RS17100	COG1122	ATPase activity
EHC64_RS17115	COG0348	domain, Protein
EHC64_RS17120	COG0437	4 iron, 4 sulfur cluster binding
EHC64_RS17125	COG1247	-acetyltransferase
EHC64_RS17155	COG1067	ATP-dependent peptidase activity
EHC64_RS17165	COG4172	Belongs to the ABC transporter superfamily
EHC64_RS17170	COG1505	serine-type exopeptidase activity
EHC64_RS17175	COG0583	DNA-binding transcription factor activity
EHC64_RS17180	COG1620	l-lactate permease
EHC64_RS17185	COG1304	FMN binding
EHC64_RS17195	COG0668	transmembrane transport
EHC64_RS17235	COG1063	alcohol dehydrogenase
EHC64_RS17240	COG0156	8-amino-7-oxononanoate synthase activity
EHC64_RS17250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_RS17270	COG0745	RESPONSE REGULATOR receiver
EHC64_RS17305	COG0346	lactoylglutathione lyase activity
EHC64_RS17325	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHC64_RS17365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC64_RS17380	COG2204	response regulator
EHC64_RS17405	COG1987	bacterial-type flagellum assembly
EHC64_RS17415	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHC64_RS17430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_RS17440	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHC64_RS17445	COG1516	flagellar protein fliS
EHC64_RS17460	COG1580	Controls the rotational direction of flagella during chemotaxis
EHC64_RS17465	COG1191	sigma factor activity
EHC64_RS17470	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EHC64_RS17475	COG1360	Flagellar Motor Protein
EHC64_RS17510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC64_RS17515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHC64_RS17525	COG0454	-acetyltransferase
EHC64_RS17535	COG2814	Major facilitator Superfamily
EHC64_RS17580	COG0628	permease
EHC64_RS17585	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC64_RS17595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC64_RS17605	COG4628	conserved protein (DUF2132)
EHC64_RS17610	COG0583	DNA-binding transcription factor activity
EHC64_RS17635	COG1686	Belongs to the peptidase S11 family
EHC64_RS17655	COG3397	chitin binding
EHC64_RS17660	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC64_RS17665	COG2095	MarC family integral membrane protein
EHC64_RS17685	COG0489	protein tyrosine kinase activity
EHC64_RS17685	COG3206	protein involved in exopolysaccharide biosynthesis
EHC64_RS17700	COG0583	DNA-binding transcription factor activity
EHC64_RS17710	COG1301	dicarboxylic acid transport
EHC64_RS17725	COG3339	Conserved Protein
EHC64_RS17730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC64_RS17735	COG0700	Nucleoside recognition
EHC64_RS17740	COG3366	ferrous iron transmembrane transporter activity
EHC64_RS17755	COG0366	Alpha amylase catalytic
EHC64_RS17760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EHC64_RS17765	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EHC64_RS17770	COG1640	4-alpha-glucanotransferase
EHC64_RS17775	COG0058	SHG alpha-glucan phosphorylase activity
EHC64_RS17790	COG2909	trisaccharide binding
EHC64_RS17805	COG1999	signal sequence binding
EHC64_RS17815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC64_RS17815	COG1263	PTS System
EHC64_RS17820	COG1162	GTPase activity
EHC64_RS17825	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EHC64_RS17835	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EHC64_RS17850	COG0531	amino acid
EHC64_RS17855	COG1982	Orn Lys Arg decarboxylase major
EHC64_RS17875	COG2356	endonuclease I
EHC64_RS17900	COG4580	involved in the transport of maltose and maltodextrins
EHC64_RS17925	COG0739	heme binding
EHC64_RS17935	COG0612	Peptidase, M16
EHC64_RS17940	COG0840	transmembrane signaling receptor activity
EHC64_RS17945	COG1120	ATPase activity
EHC64_RS17950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC64_RS17955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC64_RS17960	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EHC64_RS17965	COG4772	TonB-dependent receptor
EHC64_RS17990	COG4264	IucA IucC family
EHC64_RS17995	COG0019	diaminopimelate decarboxylase activity
EHC64_RS18000	COG1653	transport
EHC64_RS18010	COG0745	RESPONSE REGULATOR receiver
EHC64_RS18035	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHC64_RS18040	COG1129	ABC transporter
EHC64_RS18045	COG1879	ABC-type sugar transport system periplasmic component
EHC64_RS18050	COG1069	ribulokinase activity
EHC64_RS18060	COG2160	L-arabinose isomerase activity
EHC64_RS18085	COG1764	response to oxidative stress
EHC64_RS18090	COG1846	Transcriptional regulator
EHC64_RS18095	COG0450	alkyl hydroperoxide reductase
EHC64_RS18100	COG3634	alkyl hydroperoxide reductase activity
EHC64_RS18145	COG0840	transmembrane signaling receptor activity
EHC64_RS18150	COG0583	DNA-binding transcription factor activity
EHC64_RS18155	COG1486	melibiose metabolic process
EHC64_RS18170	COG2258	MOSC domain
EHC64_RS18175	COG0513	Belongs to the DEAD box helicase family
EHC64_RS18185	COG2186	Transcriptional regulator
EHC64_RS18195	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EHC64_RS18205	COG0246	Mannitol dehydrogenase
EHC64_RS18210	COG1904	glucuronate isomerase
EHC64_RS18215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC64_RS18220	COG0800	Aldolase
EHC64_RS18245	COG2207	Transcriptional regulator
EHC64_RS18255	COG1132	(ABC) transporter
EHC64_RS18300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC64_RS18330	COG0259	pyridoxamine-phosphate oxidase activity
EHC64_RS18375	COG4166	transmembrane transport
EHC64_RS18395	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHC64_RS18400	COG1263	PTS System
EHC64_RS18400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC64_RS18405	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EHC64_RS18410	COG3340	Belongs to the peptidase S51 family
EHC64_RS18430	COG1444	tRNA N-acetyltransferase activity
EHC64_RS18455	COG4608	Belongs to the ABC transporter superfamily
EHC64_RS18460	COG0444	Belongs to the ABC transporter superfamily
EHC64_RS18470	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
EHC64_RS18470	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC64_RS18495	COG0217	transcriptional regulatory protein
EHC64_RS18500	COG0772	Belongs to the SEDS family
EHC64_RS18535	COG3275	phosphorelay sensor kinase activity
EHC64_RS18540	COG3279	Response regulator of the LytR AlgR family
EHC64_RS18550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHC64_RS18585	COG0786	glutamate:sodium symporter activity
EHC64_RS18595	COG1131	(ABC) transporter
EHC64_RS18600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC64_RS18605	COG0786	glutamate:sodium symporter activity
EHC64_RS18620	COG0363	glucosamine-6-phosphate deaminase activity
EHC64_RS18640	COG1741	Belongs to the pirin family
EHC64_RS18645	COG2259	Doxx family
EHC64_RS18660	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EHC64_RS18665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHC64_RS18675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHC64_RS18715	COG3123	guanosine phosphorylase activity
EHC64_RS18725	COG5001	Diguanylate cyclase
EHC64_RS18735	COG0534	Mate efflux family protein
EHC64_RS18740	COG0564	pseudouridine synthase activity
EHC64_RS18755	COG0583	DNA-binding transcription factor activity
EHC64_RS18760	COG0561	phosphatase activity
EHC64_RS18770	COG2199	diguanylate cyclase activity
EHC64_RS18785	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EHC64_RS18790	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EHC64_RS18795	COG0583	DNA-binding transcription factor activity
EHC64_RS18810	COG1414	Transcriptional regulator
EHC64_RS18815	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_RS18825	COG1917	Cupin 2, conserved barrel domain protein
EHC64_RS18840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC64_RS18845	COG0800	Aldolase
EHC64_RS18865	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC64_RS18870	COG0823	Involved in the tonB-independent uptake of proteins
EHC64_RS18875	COG2375	cellular response to nickel ion
EHC64_RS18905	COG1357	PFAM Pentapeptide repeats (8 copies)
EHC64_RS18910	COG3047	cAMP biosynthetic process
EHC64_RS18940	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EHC64_RS18940	COG3408	Glycogen debranching enzyme
EHC64_RS18945	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EHC64_RS18955	COG0583	DNA-binding transcription factor activity
EHC64_RS18965	COG0583	DNA-binding transcription factor activity
EHC64_RS18980	COG0546	phosphoglycolate phosphatase activity
EHC64_RS19005	COG3835	regulator
EHC64_RS19010	COG2610	gluconate transmembrane transporter activity
EHC64_RS19015	COG1929	Belongs to the glycerate kinase type-1 family
EHC64_RS19020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC64_RS19055	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_RS19065	COG3005	denitrification pathway
EHC64_RS19070	COG0243	molybdopterin cofactor binding
EHC64_RS19080	COG0352	thiamine-phosphate diphosphorylase activity
EHC64_RS19085	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EHC64_RS19090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EHC64_RS19095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHC64_RS19100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHC64_RS19105	COG1116	anion transmembrane transporter activity
EHC64_RS19110	COG0351	phosphomethylpyrimidine kinase
EHC64_RS19120	COG0312	modulator of DNA gyrase
EHC64_RS19125	COG0312	modulator of DNA gyrase
EHC64_RS19130	COG1901	pseudouridine methyltransferase
EHC64_RS19190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHC64_RS19200	COG0584	glycerophosphoryl diester phosphodiesterase
EHC64_RS19210	COG0745	RESPONSE REGULATOR receiver
EHC64_RS19230	COG0811	peptide transport
EHC64_RS19235	COG0811	peptide transport
EHC64_RS19240	COG0848	biopolymer transport protein
EHC64_RS19285	COG0803	Belongs to the bacterial solute-binding protein 9 family
EHC64_RS19290	COG1121	(ABC) transporter
EHC64_RS19295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EHC64_RS19310	COG1770	oligopeptidase
EHC64_RS19315	COG2814	Major facilitator Superfamily
EHC64_RS19320	COG0010	Belongs to the arginase family
EHC64_RS19325	COG1166	arginine decarboxylase activity
EHC64_RS19335	COG0189	ligase activity
EHC64_RS19335	COG4067	protein conserved in archaea
EHC64_RS19340	COG0189	ligase activity
EHC64_RS19345	COG0583	DNA-binding transcription factor activity
EHC64_RS19390	COG3706	GGDEF domain
EHC64_RS19420	COG0579	oxidoreductase
EHC64_RS19430	COG3033	Beta-eliminating lyase
EHC64_RS19450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC64_RS19465	COG3706	GGDEF domain
EHC64_RS19470	COG0840	transmembrane signaling receptor activity
EHC64_RS19485	COG3706	GGDEF domain
EHC64_RS19490	COG0415	Belongs to the DNA photolyase family
EHC64_RS19495	COG3046	protein related to deoxyribodipyrimidine photolyase
EHC64_RS19510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC64_RS19510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC64_RS19515	COG1765	OsmC-like protein
EHC64_RS19520	COG0110	maltose O-acetyltransferase activity
EHC64_RS19560	COG1011	Hydrolase
EHC64_RS19575	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EHC64_RS19585	COG2067	long-chain fatty acid transport protein
EHC64_RS19605	COG3240	lipase activity
EHC64_RS19630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_RS19635	COG1609	Transcriptional regulator
EHC64_RS19640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC64_RS19655	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC64_RS19665	COG3842	ATPase activity
EHC64_RS19690	COG2990	Protein conserved in bacteria
EHC64_RS19700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC64_RS19705	COG2866	Carboxypeptidase
EHC64_RS19720	COG0583	DNA-binding transcription factor activity
EHC64_RS19745	COG1760	l-serine dehydratase
EHC64_RS19765	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHC64_RS19770	COG0741	lytic transglycosylase activity
EHC64_RS19790	COG1815	bacterial-type flagellum-dependent cell motility
EHC64_RS19795	COG1558	bacterial-type flagellum-dependent cell motility
EHC64_RS19800	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EHC64_RS19805	COG1749	Flagellar hook protein flgE
EHC64_RS19810	COG4787	bacterial-type flagellum-dependent cell motility
EHC64_RS19815	COG4786	Flagellar basal body rod
EHC64_RS19820	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EHC64_RS19825	COG1706	bacterial-type flagellum-dependent cell motility
EHC64_RS19835	COG4786	Flagellar basal body rod
EHC64_RS19835	COG1256	bacterial-type flagellum assembly
EHC64_RS19840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_RS19860	COG1304	FMN binding
EHC64_RS19890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC64_RS19895	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHC64_RS19900	COG0459	protein refolding
EHC64_RS19915	COG1280	lysine exporter protein (LysE YggA)
EHC64_RS19935	COG1309	transcriptional regulator
EHC64_RS19945	COG0737	Belongs to the 5'-nucleotidase family
EHC64_RS19950	COG2070	2-Nitropropane dioxygenase
EHC64_RS19955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC64_RS19965	COG0583	DNA-binding transcription factor activity
EHC64_RS19980	COG0346	lactoylglutathione lyase activity
EHC64_RS19985	COG1349	DNA-binding transcription factor activity
EHC64_RS19995	COG0753	catalase activity
EHC64_RS20005	COG1335	isochorismatase
EHC64_RS20015	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EHC64_RS20040	COG0583	DNA-binding transcription factor activity
EHC64_RS20055	COG3713	MltA-interacting MipA family protein
EHC64_RS20065	COG3015	lipoprotein NlpE involved in copper resistance
EHC64_RS20075	COG1342	Belongs to the UPF0251 family
EHC64_RS20100	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC64_RS20110	COG4948	Mandelate Racemase Muconate Lactonizing
EHC64_RS20120	COG0583	DNA-binding transcription factor activity
EHC64_RS20170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHC64_RS20215	COG3842	ATPase activity
EHC64_RS20245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC64_RS20265	COG3706	GGDEF domain
EHC64_RS20285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC64_RS20300	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC64_RS20305	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHC64_RS20325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHC64_RS20325	COG0574	Belongs to the PEP-utilizing enzyme family
EHC64_RS20330	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EHC64_RS20335	COG0252	asparaginase activity
EHC64_RS20345	COG0583	DNA-binding transcription factor activity
EHC64_RS20360	COG3122	Protein conserved in bacteria
EHC64_RS20375	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_RS20385	COG1063	alcohol dehydrogenase
EHC64_RS20390	COG1902	pentaerythritol trinitrate reductase activity
EHC64_RS20405	COG0583	DNA-binding transcription factor activity
EHC64_RS20415	COG0513	Belongs to the DEAD box helicase family
EHC64_RS20430	COG3423	Transcriptional regulator
EHC64_RS20435	COG2801	Transposase and inactivated derivatives
EHC64_RS20445	COG2842	Transposition protein
EHC64_RS20525	COG5566	PFAM Mor transcription activator
EHC64_RS20555	COG0640	Transcriptional regulator
EHC64_RS20565	COG4373	Mu-like prophage FluMu protein gp28
EHC64_RS20570	COG4383	Mu-like prophage protein gp29
EHC64_RS20590	COG4388	Caudovirus prohead serine protease
EHC64_RS20600	COG4397	Mu-like prophage major head subunit gpT
EHC64_RS20610	COG4387	Mu-like prophage protein GP36
EHC64_RS20710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC64_RS20715	COG2207	Transcriptional regulator
EHC64_RS20715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHC64_RS20745	COG2354	Protein conserved in bacteria
EHC64_RS20750	COG0418	dihydroorotase activity
EHC64_RS20760	COG0401	homolog of Blt101
EHC64_RS20770	COG3217	Mosc domain protein beta barrel domain protein
EHC64_RS20770	COG3217	Mosc domain protein beta barrel domain protein
EHC64_RS20770	COG0633	Ferredoxin
EHC64_RS20770	COG0633	Ferredoxin
EHC64_RS20775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EHC64_RS20780	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EHC64_RS20820	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EHC64_RS20825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC64_RS20835	COG0848	biopolymer transport protein
EHC64_RS20840	COG0811	peptide transport
EHC64_RS20845	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EHC64_RS20855	COG3721	Heme iron utilization protein
EHC64_RS20860	COG0748	coenzyme F420 binding
EHC64_RS20870	COG0784	Response regulator, receiver
EHC64_RS20870	COG0835	chemotaxis
EHC64_RS20880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC64_RS20915	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EHC64_RS20920	COG0783	Belongs to the Dps family
EHC64_RS20930	COG0583	DNA-binding transcription factor activity
EHC64_RS20950	COG0641	radical SAM
EHC64_RS20965	COG4934	collagen metabolic process
EHC64_RS20975	COG0366	Alpha amylase catalytic
EHC64_RS20995	COG2249	NAD(P)H dehydrogenase (quinone) activity
EHC64_RS21000	COG0589	response to stress
EHC64_RS21005	COG0488	(ABC) transporter
EHC64_RS21010	COG1505	serine-type exopeptidase activity
EHC64_RS21020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC64_RS21030	COG2067	long-chain fatty acid transport protein
EHC64_RS21040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC64_RS21050	COG2203	Gaf domain
EHC64_RS21050	COG2199	diguanylate cyclase activity
EHC64_RS21070	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC64_RS21095	COG3383	formate dehydrogenase (NAD+) activity
EHC64_RS21110	COG0842	Transport permease protein
EHC64_RS21115	COG1131	(ABC) transporter
EHC64_RS21140	COG1881	PFAM PEBP family protein
EHC64_RS21150	COG0798	PFAM Bile acid sodium symporter
EHC64_RS21170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_RS21175	COG2213	PTS system mannitol-specific
EHC64_RS21180	COG1063	alcohol dehydrogenase
EHC64_RS21190	COG1072	(Pantothenic acid kinase))
EHC64_RS21195	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHC64_RS21215	COG0814	amino acid
EHC64_RS21255	COG0739	heme binding
EHC64_RS21260	COG5001	Diguanylate cyclase
EHC64_RS21265	COG0583	DNA-binding transcription factor activity
EHC64_RS21270	COG2814	Major facilitator Superfamily
EHC64_RS21295	COG0697	spore germination
EHC64_RS21325	COG2207	Transcriptional regulator
EHC64_RS21330	COG1280	lysine exporter protein (LysE YggA)
EHC64_RS21340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC64_RS21345	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EHC64_RS21355	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EHC64_RS21380	COG1612	heme a metabolic process
EHC64_RS21385	COG0109	protoheme IX farnesyltransferase activity
EHC64_RS21390	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC64_RS21425	COG1278	Cold shock
EHC64_RS21430	COG3036	rescue of stalled ribosome
EHC64_RS21445	COG2199	diguanylate cyclase activity
EHC64_RS21465	COG0577	efflux transmembrane transporter activity
EHC64_RS21465	COG1136	(ABC) transporter
EHC64_RS21475	COG0840	transmembrane signaling receptor activity
EHC64_RS21480	COG0783	Belongs to the Dps family
EHC64_RS21490	COG2133	pyrroloquinoline quinone binding
EHC64_RS21495	COG1454	alcohol dehydrogenase
EHC64_RS21500	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EHC64_RS21540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC64_RS21545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC64_RS21550	COG3186	Phenylalanine-4-hydroxylase
EHC64_RS21555	COG2154	pterin-4-alpha-carbinolamine dehydratase
EHC64_RS21580	COG3530	Putative quorum-sensing-regulated virulence factor
EHC64_RS21585	COG0513	Belongs to the DEAD box helicase family
EHC64_RS21590	COG4628	conserved protein (DUF2132)
EHC64_RS21595	COG0133	tryptophan synthase activity
EHC64_RS21605	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EHC64_RS21615	COG0523	cobalamin synthesis protein
EHC64_RS21620	COG0513	Belongs to the DEAD box helicase family
EHC64_RS21640	COG2200	EAL domain
EHC64_RS21645	COG1119	ATPase activity
EHC64_RS21650	COG0840	transmembrane signaling receptor activity
EHC64_RS21675	COG0641	radical SAM
EHC64_RS21710	COG0582	viral genome integration into host DNA
EHC64_RS21755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EHC64_RS21770	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EHC64_RS21775	COG0513	Belongs to the DEAD box helicase family
EHC64_RS21780	COG5001	Diguanylate cyclase
EHC64_RS21790	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHC64_RS21805	COG5413	integral membrane protein
EHC64_RS21815	COG1024	Enoyl-CoA hydratase
EHC64_RS21820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EHC64_RS21825	COG1960	acyl-CoA dehydrogenase activity
EHC64_RS21835	COG0183	Belongs to the thiolase family
EHC64_RS21850	COG1024	Enoyl-CoA hydratase
EHC64_RS21855	COG1024	Enoyl-CoA hydratase
EHC64_RS21870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EHC64_RS21875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHC64_RS21880	COG1845	cytochrome c oxidase, subunit III
EHC64_RS21885	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EHC64_RS21890	COG0109	protoheme IX farnesyltransferase activity
EHC64_RS21905	COG1902	pentaerythritol trinitrate reductase activity
EHC64_RS21915	COG1126	abc transporter atp-binding protein
EHC64_RS21920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_RS21925	COG4215	(ABC) transporter
EHC64_RS21930	COG4160	amino acid transport
EHC64_RS21945	COG0625	glutathione transferase activity
EHC64_RS21985	COG0443	Heat shock 70 kDa protein
EHC64_RS21990	COG2847	Copper chaperone PCu(A)C
EHC64_RS22015	COG4607	ABC-type enterochelin transport system periplasmic component
EHC64_RS22020	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC64_RS22025	COG4605	iron ion homeostasis
EHC64_RS22030	COG4604	ABC transporter, ATP-binding protein
EHC64_RS22035	COG0789	Transcriptional regulator
EHC64_RS22050	COG1629	transport
EHC64_RS22050	COG4771	TonB-dependent receptor
EHC64_RS22085	COG1289	transmembrane transporter activity
EHC64_RS22090	COG0210	DNA helicase
EHC64_RS22095	COG1803	Methylglyoxal synthase
EHC64_RS22100	COG1879	ABC-type sugar transport system periplasmic component
EHC64_RS22105	COG0784	Response regulator, receiver
EHC64_RS22105	COG2198	Histidine kinase
EHC64_RS22105	COG2205	protein histidine kinase activity
EHC64_RS22120	COG0745	RESPONSE REGULATOR receiver
EHC64_RS22125	COG3119	arylsulfatase activity
EHC64_RS22130	COG3119	arylsulfatase activity
EHC64_RS22145	COG3119	arylsulfatase activity
EHC64_RS22150	COG0641	radical SAM
EHC64_RS22155	COG0714	Associated with various cellular activities
EHC64_RS22185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC64_RS22190	COG0583	DNA-binding transcription factor activity
EHC64_RS22195	COG1597	lipid kinase activity
EHC64_RS22200	COG3111	PFAM Bacterial OB fold (BOF) protein
EHC64_RS22220	COG0641	radical SAM
EHC64_RS22250	COG0501	Belongs to the peptidase M48B family
EHC64_RS22255	COG1704	LemA family
EHC64_RS22260	COG3069	C4-dicarboxylate transmembrane transporter activity
EHC64_RS22270	COG1214	PFAM Peptidase M22, glycoprotease
EHC64_RS22270	COG0456	acetyltransferase
EHC64_RS22290	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EHC64_RS22330	COG4964	Belongs to the GSP D family
EHC64_RS22390	COG0583	DNA-binding transcription factor activity
EHC64_RS22395	COG0583	DNA-binding transcription factor activity
EHC64_RS22410	COG5001	Diguanylate cyclase
EHC64_RS22410	COG3300	MHYT domain
EHC64_RS22415	COG2197	response regulator
EHC64_RS22420	COG3706	GGDEF domain
EHC64_RS22430	COG2197	response regulator
EHC64_RS22455	COG0784	Response regulator, receiver
EHC64_RS22455	COG0835	chemotaxis
EHC64_RS22475	COG2962	Rard protein
EHC64_RS22490	COG0671	phosphoesterase, PA-phosphatase related
EHC64_RS22505	COG2076	Multidrug Resistance protein
EHC64_RS22535	COG0471	metal ion transport
EHC64_RS22540	COG3290	protein histidine kinase activity
EHC64_RS22545	COG4565	transcriptional regulatory protein
EHC64_RS22555	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EHC64_RS22555	COG0069	glutamate synthase activity
EHC64_RS22565	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EHC64_RS22590	COG1902	pentaerythritol trinitrate reductase activity
EHC64_RS22595	COG0346	lactoylglutathione lyase activity
EHC64_RS22615	COG2239	Acts as a magnesium transporter
EHC64_RS22645	COG0242	peptide deformylase activity
EHC64_RS22695	COG2176	DNA-directed DNA polymerase activity
EHC64_RS22700	COG0583	DNA-binding transcription factor activity
EHC64_RS22705	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHC64_RS22745	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHC64_RS22745	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHC64_RS22750	COG0509	glycine decarboxylation via glycine cleavage system
EHC64_RS22755	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHC64_RS22795	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EHC64_RS22795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC64_RS22795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC64_RS22800	COG1105	Belongs to the carbohydrate kinase PfkB family
EHC64_RS22805	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_RS22805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_RS22810	COG1609	Transcriptional regulator
EHC64_RS22830	COG2203	Gaf domain
EHC64_RS22830	COG2199	diguanylate cyclase activity
EHC64_RS22830	COG2200	EAL domain
EHC64_RS22835	COG0765	amino acid transport
EHC64_RS22840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_RS22845	COG0765	amino acid transport
EHC64_RS22850	COG1126	abc transporter atp-binding protein
EHC64_RS22855	COG0469	pyruvate kinase activity
EHC64_RS22860	COG2271	Major facilitator Superfamily
EHC64_RS22865	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC64_RS22885	COG1979	alcohol dehydrogenase
EHC64_RS22890	COG2207	Transcriptional regulator
EHC64_RS22905	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC64_RS22910	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EHC64_RS22915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC64_RS22935	COG0784	Response regulator, receiver
EHC64_RS22935	COG3437	response regulator, receiver
EHC64_RS22945	COG0546	phosphoglycolate phosphatase activity
EHC64_RS22950	COG0840	transmembrane signaling receptor activity
EHC64_RS22960	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
EHC64_RS22965	COG0513	Belongs to the DEAD box helicase family
EHC64_RS22970	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EHC64_RS22985	COG3038	cytochrome b561
EHC64_RS22990	COG2353	YceI-like domain
EHC64_RS22995	COG2116	formate transmembrane transporter activity
EHC64_RS23000	COG0583	DNA-binding transcription factor activity
EHC64_RS23010	COG3593	DNA synthesis involved in DNA repair
EHC64_RS23015	COG0737	Belongs to the 5'-nucleotidase family
EHC64_RS23020	COG0861	Integral membrane protein TerC family
EHC64_RS23035	COG2267	carboxylic ester hydrolase activity
EHC64_RS23040	COG2067	long-chain fatty acid transport protein
EHC64_RS23055	COG2050	protein possibly involved in aromatic compounds catabolism
EHC64_RS23065	COG4533	DNA binding
EHC64_RS23090	COG0484	heat shock protein binding
EHC64_RS23100	COG3300	MHYT domain
EHC64_RS23100	COG5001	Diguanylate cyclase
EHC64_RS23105	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EHC64_RS23115	COG4181	ATPase activity
EHC64_RS23120	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EHC64_RS23130	COG1984	allophanate hydrolase subunit 2
EHC64_RS23135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EHC64_RS23140	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EHC64_RS23145	COG5002	protein histidine kinase activity
EHC64_RS23145	COG5001	Diguanylate cyclase
EHC64_RS23145	COG3447	MASE1 domain protein
EHC64_RS23150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EHC64_RS23160	COG4771	TonB-dependent receptor
EHC64_RS23160	COG1629	transport
EHC64_RS23165	COG0583	DNA-binding transcription factor activity
EHC64_RS23170	COG0045	succinate-CoA ligase (ADP-forming) activity
EHC64_RS23170	COG1042	CoA-binding domain protein
EHC64_RS23170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC64_RS23180	COG1181	Belongs to the D-alanine--D-alanine ligase family
EHC64_RS23190	COG0023	Translation Initiation Factor
EHC64_RS23265	COG0583	DNA-binding transcription factor activity
EHC64_RS23275	COG0589	response to stress
EHC64_RS23280	COG3140	Belongs to the UPF0181 family
EHC64_RS23305	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EHC64_RS23310	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EHC64_RS23325	COG0745	RESPONSE REGULATOR receiver
EHC64_RS23325	COG3706	GGDEF domain
EHC64_RS23335	COG5001	Diguanylate cyclase
EHC64_RS23335	COG2203	Gaf domain
EHC64_RS23335	COG4251	negative regulation of phosphorylation
EHC64_RS23335	COG3706	GGDEF domain
EHC64_RS23345	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EHC64_RS23350	COG4149	molybdate abc transporter
EHC64_RS23355	COG0725	ABC transporter, periplasmic molybdate-binding protein
EHC64_RS23360	COG1492	cobalamin metabolic process
EHC64_RS23365	COG3111	PFAM Bacterial OB fold (BOF) protein
EHC64_RS23375	COG0189	ligase activity
EHC64_RS23375	COG4067	protein conserved in archaea
EHC64_RS23395	COG0534	Mate efflux family protein
EHC64_RS23400	COG0602	queuosine metabolic process
EHC64_RS23405	COG1328	CTP reductase activity
EHC64_RS23420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC64_RS23445	COG0446	pyridine nucleotide-disulphide oxidoreductase
EHC64_RS23450	COG0243	molybdopterin cofactor binding
EHC64_RS23460	COG0583	DNA-binding transcription factor activity
EHC64_RS23465	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHC64_RS23475	COG2197	response regulator
EHC64_RS23480	COG3851	Histidine kinase
EHC64_RS23485	COG2271	Major facilitator Superfamily
EHC64_RS23510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHC64_RS23515	COG3118	belongs to the thioredoxin family
EHC64_RS23520	COG2814	Major facilitator Superfamily
EHC64_RS23530	COG0534	Mate efflux family protein
EHC64_RS23560	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EHC64_RS23580	COG2116	formate transmembrane transporter activity
EHC64_RS23585	COG2146	nitrite reductase [NAD(P)H] activity
EHC64_RS23590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC64_RS23595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC64_RS23635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC64_RS23635	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC64_RS23680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC64_RS23700	COG0277	FAD linked oxidase domain protein
EHC64_RS23705	COG0583	DNA-binding transcription factor activity
EHC64_RS23725	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EHC64_RS23740	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EHC64_RS23755	COG1288	antiporter activity
EHC64_RS23765	COG2814	Major facilitator Superfamily
EHC64_RS23775	COG3040	lipid binding
EHC64_RS23795	COG0419	ATPase involved in DNA repair
EHC64_RS23800	COG0420	3'-5' exonuclease activity
EHC64_RS23815	COG3501	Rhs element vgr protein
EHC64_RS23870	COG0631	protein serine/threonine phosphatase activity
EHC64_RS23905	COG2815	serine threonine protein kinase
EHC64_RS23905	COG0515	serine threonine protein kinase
EHC64_RS23960	COG2146	nitrite reductase [NAD(P)H] activity
EHC64_RS23960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC64_RS23965	COG1116	anion transmembrane transporter activity
EHC64_RS23970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHC64_RS23975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHC64_RS23985	COG3707	response regulator
EHC64_RS24005	COG1648	precorrin-2 dehydrogenase activity
EHC64_RS24005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EHC64_RS24010	COG0243	molybdopterin cofactor binding
EHC64_RS24015	COG0456	acetyltransferase
EHC64_RS24020	COG0814	amino acid
EHC64_RS24030	COG0745	RESPONSE REGULATOR receiver
EHC64_RS24030	COG3706	GGDEF domain
EHC64_RS24050	COG1785	Belongs to the alkaline phosphatase family
EHC64_RS24065	COG0745	RESPONSE REGULATOR receiver
EHC64_RS24085	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EHC64_RS24100	COG1609	Transcriptional regulator
EHC64_RS24105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC64_RS24110	COG1879	ABC-type sugar transport system periplasmic component
EHC64_RS24115	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHC64_RS24120	COG1129	ABC transporter
EHC64_RS24125	COG1869	D-ribose catabolic process
EHC64_RS24130	COG5001	Diguanylate cyclase
EHC64_RS24135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHC64_RS24195	COG0784	Response regulator, receiver
EHC64_RS24195	COG2205	protein histidine kinase activity
EHC64_RS24215	COG3300	MHYT domain
EHC64_RS24215	COG5001	Diguanylate cyclase
EHC64_RS24225	COG0330	HflC and HflK could
EHC64_RS24240	COG4175	Glycine betaine
EHC64_RS24240	COG0517	IMP dehydrogenase activity
EHC64_RS24245	COG4176	ABC-type proline glycine betaine transport system permease component
EHC64_RS24260	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_RS24265	COG1309	transcriptional regulator
EHC64_RS24270	COG3706	GGDEF domain
EHC64_RS24295	COG1024	Enoyl-CoA hydratase
EHC64_RS24300	COG1960	acyl-CoA dehydrogenase activity
EHC64_RS24310	COG0183	Belongs to the thiolase family
EHC64_RS24320	COG1960	acyl-CoA dehydrogenase activity
EHC64_RS24325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EHC64_RS24345	COG2205	protein histidine kinase activity
EHC64_RS24345	COG3437	response regulator, receiver
EHC64_RS24345	COG3850	Histidine kinase
EHC64_RS24345	COG4999	Histidine kinase
EHC64_RS24360	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EHC64_RS24360	COG3264	Mechanosensitive ion channel
EHC64_RS24370	COG0110	maltose O-acetyltransferase activity
EHC64_RS24375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC64_RS24380	COG1271	oxidase subunit
EHC64_RS24385	COG1294	oxidase, subunit
EHC64_RS24395	COG0384	phenazine biosynthesis protein PhzF
EHC64_RS24400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EHC64_RS24405	COG0789	Transcriptional regulator
EHC64_RS24415	COG3474	cytochrome
EHC64_RS24425	COG0500	methyltransferase
EHC64_RS24485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC64_RS24610	COG2356	endonuclease I
EHC64_RS24700	COG1683	Conserved Protein
EHC64_RS24720	COG2026	Addiction module toxin, RelE StbE family
EHC64_RS24725	COG4115	mRNA cleavage
EHC64_RS24730	COG2161	toxin-antitoxin pair type II binding
EHC64_RS24750	COG0494	nUDIX hydrolase
EHC64_RS24780	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_RS24795	COG2199	diguanylate cyclase activity
EHC64_RS24795	COG2202	Pas domain
EHC64_RS24795	COG2200	EAL domain
EHC64_RS24820	COG0840	transmembrane signaling receptor activity
EHC64_RS24835	COG0840	transmembrane signaling receptor activity
EHC64_RS24890	COG0464	growth
EHC64_RS24895	COG4974	Belongs to the 'phage' integrase family
EHC64_RS24900	COG0516	GMP reductase activity
EHC64_RS24905	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EHC64_RS24905	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EHC64_RS24920	COG4989	oxidoreductase activity
EHC64_RS24935	COG0038	chloride channel
EHC64_RS24945	COG1914	H( )-stimulated, divalent metal cation uptake system
EHC64_RS24950	COG0302	gtp cyclohydrolase
EHC64_RS24960	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EHC64_RS24980	COG2897	thiosulfate sulfurtransferase activity
EHC64_RS25005	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHC64_RS25010	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHC64_RS25015	COG0840	transmembrane signaling receptor activity
EHC64_RS25025	COG2814	Major facilitator Superfamily
EHC64_RS25030	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC64_RS25040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC64_RS25050	COG0840	transmembrane signaling receptor activity
EHC64_RS25070	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC64_RS25085	COG2197	response regulator
EHC64_RS25090	COG3850	Histidine kinase
EHC64_RS25095	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EHC64_RS25105	COG0243	molybdopterin cofactor binding
EHC64_RS25115	COG3005	denitrification pathway
EHC64_RS25135	COG0183	Belongs to the thiolase family
EHC64_RS25155	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC64_RS25160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC64_RS25185	COG1522	sequence-specific DNA binding
EHC64_RS25205	COG1566	PFAM secretion protein HlyD family protein
EHC64_RS25215	COG2205	protein histidine kinase activity
EHC64_RS25215	COG0784	Response regulator, receiver
EHC64_RS25220	COG1879	ABC-type sugar transport system periplasmic component
EHC64_RS25225	COG2827	Endonuclease containing a URI domain
EHC64_RS25230	COG3132	Protein of unknown function, DUF480
EHC64_RS25245	COG2926	Belongs to the UPF0265 family
EHC64_RS25250	COG0534	Mate efflux family protein
EHC64_RS25255	COG0673	inositol 2-dehydrogenase activity
EHC64_RS25260	COG2205	protein histidine kinase activity
EHC64_RS25260	COG5002	protein histidine kinase activity
EHC64_RS25260	COG0784	Response regulator, receiver
EHC64_RS25285	COG1522	sequence-specific DNA binding
EHC64_RS25295	COG0531	amino acid
EHC64_RS25310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EHC64_RS25315	COG2239	Acts as a magnesium transporter
EHC64_RS25320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EHC64_RS25325	COG0402	S-adenosylhomocysteine deaminase activity
EHC64_RS25335	COG1418	mRNA catabolic process
EHC64_RS25350	COG2814	Major facilitator Superfamily
EHC64_RS25360	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC64_RS25380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC64_RS25400	COG4221	oxidoreductase activity
EHC64_RS25405	COG0745	RESPONSE REGULATOR receiver
EHC64_RS25410	COG2205	protein histidine kinase activity
EHC64_RS25420	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EHC64_RS25425	COG2194	sulfuric ester hydrolase activity
EHC64_RS25430	COG0673	inositol 2-dehydrogenase activity
EHC64_RS25440	COG2814	Major facilitator Superfamily
EHC64_RS25455	COG1846	Transcriptional regulator
EHC64_RS25465	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC64_RS25470	COG1741	Belongs to the pirin family
EHC64_RS25475	COG1278	Cold shock
EHC64_RS25490	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHC64_RS25510	COG1686	Belongs to the peptidase S11 family
EHC64_RS25520	COG0625	glutathione transferase activity
EHC64_RS25530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EHC64_RS25535	COG0494	nUDIX hydrolase
EHC64_RS25540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHC64_RS25560	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_RS25580	COG3746	phosphate-selective porin O and P
EHC64_RS25600	COG3833	ABC-type maltose transport systems, permease component
EHC64_RS25605	COG1175	transmembrane transport
EHC64_RS25615	COG3842	ATPase activity
EHC64_RS25680	COG1309	transcriptional regulator
EHC64_RS25685	COG2130	NADP-dependent
EHC64_RS25695	COG0753	catalase activity
EHC64_RS25700	COG2084	Dehydrogenase
EHC64_RS25705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC64_RS25710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC64_RS25720	COG2207	Transcriptional regulator
EHC64_RS25725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC64_RS25725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_RS25725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC64_RS25740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC64_RS25745	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EHC64_RS25755	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC64_RS25760	COG0569	domain protein
EHC64_RS25770	COG5002	protein histidine kinase activity
EHC64_RS25775	COG1132	(ABC) transporter
EHC64_RS25780	COG4774	siderophore transport
EHC64_RS25785	COG1120	ATPase activity
EHC64_RS25790	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EHC64_RS25805	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EHC64_RS25805	COG2885	chlorophyll binding
EHC64_RS25840	COG2197	response regulator
EHC64_RS25850	COG0840	transmembrane signaling receptor activity
EHC64_RS25860	COG0714	Associated with various cellular activities
EHC64_RS25925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC64_RS25950	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EHC64_RS25950	COG2885	chlorophyll binding
EHC64_RS25960	COG2948	multi-organism process
EHC64_RS25975	COG3701	Conjugal transfer protein
EHC64_RS25995	COG3451	type IV secretory pathway VirB4
EHC64_RS26060	COG1192	Involved in chromosome partitioning
EHC64_RS26090	COG5492	domain, Protein
EHC64_RS26090	COG4932	domain protein
EHC64_RS26130	COG2885	chlorophyll binding
EHC64_RS26185	COG2337	Toxic component of a toxin-antitoxin (TA) module
EHC64_RS26195	COG4974	Belongs to the 'phage' integrase family
EHC64_RS26215	COG5492	domain, Protein
EHC64_RS26215	COG4932	domain protein
EHC64_RS26235	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EHC64_RS26250	COG0739	heme binding
EHC64_RS26415	COG4962	Type ii secretion system protein e
EHC64_RS26470	COG2801	Transposase and inactivated derivatives
EHC64_RS26535	COG1560	Kdo2-lipid A biosynthetic process
EHC64_RS26540	COG0251	oxidation-reduction process
EHC64_RS26550	COG2957	Belongs to the agmatine deiminase family
EHC64_RS26555	COG0531	amino acid
EHC64_RS26560	COG0549	Belongs to the carbamate kinase family
EHC64_RS26670	COG1192	Involved in chromosome partitioning
EHC64_RS26685	COG3157	Type VI secretion system effector, Hcp
EHC64_RS26995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC64_RS27030	COG3504	Conjugal transfer protein
EHC64_RS27045	COG4962	Type ii secretion system protein e
EHC64_RS27055	COG3451	type IV secretory pathway VirB4
EHC64_RS27060	COG5268	conjugation
EHC64_RS27085	COG1192	Involved in chromosome partitioning
EHC64_RS27110	COG0419	ATPase involved in DNA repair