locus-tag	class	description
EHC68_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EHC68_RS00010	COG0592	DNA-directed DNA polymerase activity
EHC68_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EHC68_RS00020	COG0187	DNA topoisomerase II activity
EHC68_RS00040	COG0071	Belongs to the small heat shock protein (HSP20) family
EHC68_RS00045	COG3977	Valine--pyruvate aminotransferase
EHC68_RS00050	COG0366	Alpha amylase catalytic
EHC68_RS00055	COG0751	glycine-tRNA ligase activity
EHC68_RS00060	COG0752	glycyl-tRNA synthetase alpha subunit
EHC68_RS00065	COG2119	membrane
EHC68_RS00075	COG0425	Belongs to the sulfur carrier protein TusA family
EHC68_RS00090	COG0604	alcohol dehydrogenase
EHC68_RS00095	COG0183	Belongs to the thiolase family
EHC68_RS00100	COG1024	Enoyl-CoA hydratase
EHC68_RS00100	COG1250	3-hydroxyacyl-CoA dehydrogenase
EHC68_RS00105	COG1739	Uncharacterized protein family UPF0029
EHC68_RS00110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC68_RS00165	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHC68_RS00170	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EHC68_RS00180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EHC68_RS00185	COG2104	thiamine diphosphate biosynthetic process
EHC68_RS00190	COG2022	thiamine diphosphate biosynthetic process
EHC68_RS00200	COG0006	proline dipeptidase activity
EHC68_RS00200	COG0006	proline dipeptidase activity
EHC68_RS00230	COG3220	belongs to the UPF0276 family
EHC68_RS00240	COG0210	DNA helicase
EHC68_RS00250	COG0405	Gamma-glutamyltransferase
EHC68_RS00255	COG1280	lysine exporter protein (LysE YggA)
EHC68_RS00265	COG2962	Rard protein
EHC68_RS00270	COG0514	ATP-dependent DNA helicase (RecQ)
EHC68_RS00285	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EHC68_RS00290	COG0248	Ppx GppA phosphatase
EHC68_RS00295	COG0513	Belongs to the DEAD box helicase family
EHC68_RS00300	COG3118	belongs to the thioredoxin family
EHC68_RS00305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EHC68_RS00320	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EHC68_RS00325	COG0633	Ferredoxin
EHC68_RS00380	COG3071	HemY protein
EHC68_RS00385	COG2959	enzyme of heme biosynthesis
EHC68_RS00390	COG1587	Uroporphyrinogen-III synthase
EHC68_RS00395	COG0181	hydroxymethylbilane synthase activity
EHC68_RS00400	COG3072	Adenylate cyclase
EHC68_RS00405	COG1965	Belongs to the frataxin family
EHC68_RS00415	COG0019	diaminopimelate decarboxylase activity
EHC68_RS00420	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EHC68_RS00430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EHC68_RS00440	COG2199	diguanylate cyclase activity
EHC68_RS00440	COG3287	FIST C domain
EHC68_RS00440	COG2200	EAL domain
EHC68_RS00460	COG0561	phosphatase activity
EHC68_RS00465	COG2267	carboxylic ester hydrolase activity
EHC68_RS00470	COG1280	lysine exporter protein (LysE YggA)
EHC68_RS00475	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EHC68_RS00480	COG0640	Transcriptional regulator
EHC68_RS00485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC68_RS00540	COG2095	MarC family integral membrane protein
EHC68_RS00550	COG0742	ribosomal rna small subunit methyltransferase
EHC68_RS00555	COG0552	protein localization to endoplasmic reticulum
EHC68_RS00560	COG2884	Cell division ATP-binding protein ftsE
EHC68_RS00565	COG2177	Part of the ABC transporter FtsEX involved in
EHC68_RS00575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC68_RS00580	COG0705	Rhomboid family
EHC68_RS00585	COG1580	Controls the rotational direction of flagella during chemotaxis
EHC68_RS00590	COG3161	chorismate lyase activity
EHC68_RS00595	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EHC68_RS00600	COG2937	Belongs to the GPAT DAPAT family
EHC68_RS00610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHC68_RS00615	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EHC68_RS00620	COG0534	Mate efflux family protein
EHC68_RS00625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC68_RS00645	COG0789	Transcriptional regulator
EHC68_RS00715	COG2003	Belongs to the UPF0758 family
EHC68_RS00725	COG0328	RNA-DNA hybrid ribonuclease activity
EHC68_RS00730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHC68_RS00750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHC68_RS00755	COG4206	TonB-dependent receptor
EHC68_RS00765	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EHC68_RS00830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHC68_RS00840	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EHC68_RS00875	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHC68_RS00885	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EHC68_RS00890	COG0250	Participates in transcription elongation, termination and antitermination
EHC68_RS00895	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EHC68_RS00900	COG0081	regulation of translation
EHC68_RS00905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EHC68_RS00910	COG0222	ribosome binding
EHC68_RS00915	COG0085	RNA polymerase activity
EHC68_RS00920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHC68_RS00925	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EHC68_RS00930	COG2816	NAD+ diphosphatase activity
EHC68_RS00945	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EHC68_RS00950	COG1573	uracil-dna glycosylase
EHC68_RS00955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC68_RS00960	COG3068	Protein conserved in bacteria
EHC68_RS00965	COG1253	flavin adenine dinucleotide binding
EHC68_RS00980	COG0151	Belongs to the GarS family
EHC68_RS00990	COG0138	bifunctional purine biosynthesis protein purh
EHC68_RS01000	COG0789	Transcriptional regulator
EHC68_RS01005	COG3710	Transcriptional regulator
EHC68_RS01015	COG0531	amino acid
EHC68_RS01020	COG1982	Orn Lys Arg decarboxylase major
EHC68_RS01080	COG3706	GGDEF domain
EHC68_RS01085	COG0488	(ABC) transporter
EHC68_RS01090	COG2814	Major facilitator Superfamily
EHC68_RS01095	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EHC68_RS01100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC68_RS01105	COG2264	protein methyltransferase activity
EHC68_RS01115	COG0439	Biotin carboxylase
EHC68_RS01120	COG0511	ligase activity, forming carbon-carbon bonds
EHC68_RS01125	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EHC68_RS01130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC68_RS01145	COG2814	Major facilitator Superfamily
EHC68_RS01150	COG2205	protein histidine kinase activity
EHC68_RS01150	COG0784	Response regulator, receiver
EHC68_RS01175	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC68_RS01185	COG3263	regulation of cellular component size
EHC68_RS01195	COG4232	protein-disulfide reductase activity
EHC68_RS01200	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EHC68_RS01205	COG1027	Aspartate ammonia-lyase
EHC68_RS01210	COG3030	protein affecting phage T7 exclusion by the F plasmid
EHC68_RS01215	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EHC68_RS01225	COG2205	protein histidine kinase activity
EHC68_RS01230	COG0745	RESPONSE REGULATOR receiver
EHC68_RS01235	COG3678	ATP-independent chaperone mediated protein folding
EHC68_RS01245	COG0205	6-phosphofructokinase activity
EHC68_RS01250	COG0534	Mate efflux family protein
EHC68_RS01255	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHC68_RS01260	COG0459	protein refolding
EHC68_RS01275	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC68_RS01285	COG1509	lysine 2,3-aminomutase activity
EHC68_RS01290	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHC68_RS01300	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EHC68_RS01305	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EHC68_RS01310	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EHC68_RS01315	COG1053	succinate dehydrogenase
EHC68_RS01325	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EHC68_RS01345	COG4942	peptidase
EHC68_RS01350	COG1045	serine acetyltransferase
EHC68_RS01355	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EHC68_RS01360	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EHC68_RS01365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC68_RS01370	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EHC68_RS01385	COG0471	metal ion transport
EHC68_RS01390	COG0688	phosphatidylethanolamine metabolic process
EHC68_RS01395	COG1162	GTPase activity
EHC68_RS01400	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EHC68_RS01470	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EHC68_RS01475	COG0802	atpase or kinase
EHC68_RS01485	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EHC68_RS01490	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EHC68_RS01500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EHC68_RS01505	COG0330	HflC and HflK could
EHC68_RS01510	COG0330	HflC and HflK could
EHC68_RS01515	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EHC68_RS01520	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EHC68_RS01530	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EHC68_RS01535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC68_RS01535	COG1017	nitric oxide dioxygenase activity
EHC68_RS01540	COG1959	2 iron, 2 sulfur cluster binding
EHC68_RS01545	COG0557	exoribonuclease II activity
EHC68_RS01550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC68_RS01555	COG0546	phosphoglycolate phosphatase activity
EHC68_RS01560	COG0180	Tryptophanyl-tRNA synthetase
EHC68_RS01595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EHC68_RS01605	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_RS01615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC68_RS01620	COG3954	Phosphoribulokinase
EHC68_RS01625	COG3089	Belongs to the UPF0270 family
EHC68_RS01630	COG0429	hydrolase of the alpha beta-hydrolase fold
EHC68_RS01640	COG0488	(ABC) transporter
EHC68_RS01650	COG2249	NAD(P)H dehydrogenase (quinone) activity
EHC68_RS01665	COG1047	Peptidyl-prolyl cis-trans
EHC68_RS01675	COG1446	asparaginase
EHC68_RS01680	COG2900	Belongs to the SlyX family
EHC68_RS01690	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC68_RS01695	COG2964	Protein conserved in bacteria
EHC68_RS01700	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EHC68_RS01705	COG2923	Belongs to the DsrF TusC family
EHC68_RS01710	COG2168	tRNA wobble position uridine thiolation
EHC68_RS01720	COG0049	tRNA binding
EHC68_RS01725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC68_RS01730	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHC68_RS01735	COG2906	2 iron, 2 sulfur cluster binding
EHC68_RS01745	COG0281	malic enzyme
EHC68_RS01755	COG0626	cystathionine gamma-synthase activity
EHC68_RS01760	COG0527	aspartate kinase activity
EHC68_RS01760	COG0460	homoserine dehydrogenase
EHC68_RS01765	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EHC68_RS01775	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EHC68_RS01780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC68_RS01785	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EHC68_RS01790	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EHC68_RS01795	COG0137	argininosuccinate synthase activity
EHC68_RS01800	COG0165	Argininosuccinate lyase
EHC68_RS01800	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EHC68_RS01815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EHC68_RS01815	COG0678	peroxiredoxin activity
EHC68_RS01825	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EHC68_RS01855	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EHC68_RS01860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EHC68_RS01870	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EHC68_RS01875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EHC68_RS01880	COG0360	Binds together with S18 to 16S ribosomal RNA
EHC68_RS01885	COG2965	DNA replication, synthesis of RNA primer
EHC68_RS01895	COG0359	binds to the 23S rRNA
EHC68_RS01905	COG0305	Participates in initiation and elongation during chromosome replication
EHC68_RS01910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC68_RS01920	COG0432	Pfam Uncharacterised protein family UPF0047
EHC68_RS01925	COG0166	Belongs to the GPI family
EHC68_RS01935	COG0735	belongs to the Fur family
EHC68_RS01945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC68_RS01970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EHC68_RS01975	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC68_RS01980	COG0175	sulfate reduction
EHC68_RS02040	COG3335	DDE superfamily endonuclease
EHC68_RS02055	COG0646	methionine synthase
EHC68_RS02055	COG1410	methionine synthase
EHC68_RS02060	COG0527	aspartate kinase activity
EHC68_RS02065	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EHC68_RS02075	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EHC68_RS02090	COG0629	single-stranded DNA binding
EHC68_RS02095	COG2199	diguanylate cyclase activity
EHC68_RS02095	COG2200	EAL domain
EHC68_RS02120	COG3409	Peptidoglycan-binding domain 1 protein
EHC68_RS02120	COG3267	Type II secretory pathway component ExeA
EHC68_RS02130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC68_RS02135	COG1459	type II secretion system
EHC68_RS02180	COG1077	Cell shape determining protein MreB Mrl
EHC68_RS02185	COG1792	Involved in formation and maintenance of cell shape
EHC68_RS02190	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EHC68_RS02195	COG0424	maF-like protein
EHC68_RS02200	COG1530	ribonuclease E activity
EHC68_RS02205	COG3164	Protein of unknown function
EHC68_RS02210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHC68_RS02215	COG0312	modulator of DNA gyrase
EHC68_RS02220	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EHC68_RS02225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EHC68_RS02240	COG0564	pseudouridine synthase activity
EHC68_RS02245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHC68_RS02250	COG3028	Belongs to the UPF0307 family
EHC68_RS02255	COG0312	modulator of DNA gyrase
EHC68_RS02260	COG2239	Acts as a magnesium transporter
EHC68_RS02265	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_RS02270	COG1660	Displays ATPase and GTPase activities
EHC68_RS02275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_RS02280	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHC68_RS02290	COG1137	ATPase activity
EHC68_RS02295	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EHC68_RS02305	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EHC68_RS02305	COG0517	IMP dehydrogenase activity
EHC68_RS02315	COG1127	ABC transporter
EHC68_RS02320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EHC68_RS02325	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EHC68_RS02330	COG2854	intermembrane phospholipid transfer
EHC68_RS02340	COG5007	Belongs to the BolA IbaG family
EHC68_RS02345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHC68_RS02350	COG0204	Acyl-transferase
EHC68_RS02355	COG0251	oxidation-reduction process
EHC68_RS02360	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EHC68_RS02365	COG0540	Belongs to the ATCase OTCase family
EHC68_RS02375	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EHC68_RS02380	COG2235	arginine
EHC68_RS02410	COG0525	valine-tRNA ligase activity
EHC68_RS02415	COG2927	DNA polymerase III (CHI subunit)
EHC68_RS02420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHC68_RS02425	COG0795	lipopolysaccharide-transporting ATPase activity
EHC68_RS02430	COG0795	lipopolysaccharide-transporting ATPase activity
EHC68_RS02440	COG4325	translation initiation factor activity
EHC68_RS02445	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_RS02475	COG0726	polysaccharide deacetylase
EHC68_RS02480	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EHC68_RS02485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EHC68_RS02490	COG1447	Phosphotransferase system cellobiose-specific component IIA
EHC68_RS02495	COG1486	melibiose metabolic process
EHC68_RS02500	COG3394	polysaccharide catabolic process
EHC68_RS02510	COG3437	response regulator, receiver
EHC68_RS02560	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_RS02590	COG0840	transmembrane signaling receptor activity
EHC68_RS02630	COG0741	lytic transglycosylase activity
EHC68_RS02635	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EHC68_RS02645	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EHC68_RS02655	COG2066	Belongs to the glutaminase family
EHC68_RS02660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHC68_RS02665	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EHC68_RS02675	COG1872	DUF167
EHC68_RS02680	COG0762	integral membrane protein
EHC68_RS02685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHC68_RS02690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EHC68_RS02705	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EHC68_RS02710	COG1678	Uncharacterized ACR, COG1678
EHC68_RS02715	COG0189	ligase activity
EHC68_RS02720	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EHC68_RS02725	COG2356	endonuclease I
EHC68_RS02730	COG3091	SprT-like family
EHC68_RS02740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHC68_RS02750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHC68_RS02755	COG0583	DNA-binding transcription factor activity
EHC68_RS02760	COG4771	TonB-dependent receptor
EHC68_RS02765	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC68_RS02770	COG0126	phosphoglycerate kinase activity
EHC68_RS02775	COG0191	fructose-bisphosphate aldolase activity
EHC68_RS02780	COG0668	transmembrane transport
EHC68_RS02785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EHC68_RS02795	COG0583	DNA-binding transcription factor activity
EHC68_RS02805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC68_RS02810	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EHC68_RS02815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EHC68_RS02825	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EHC68_RS02835	COG3079	Belongs to the UPF0149 family
EHC68_RS02840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC68_RS02845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC68_RS02860	COG0354	folic acid binding
EHC68_RS02865	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EHC68_RS02875	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EHC68_RS02885	COG1595	DNA-templated transcription, initiation
EHC68_RS02890	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EHC68_RS02900	COG3086	response to oxidative stress
EHC68_RS02905	COG0481	GTPase activity
EHC68_RS02910	COG0681	Belongs to the peptidase S26 family
EHC68_RS02915	COG0571	ribonuclease III activity
EHC68_RS02920	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EHC68_RS02925	COG1381	Involved in DNA repair and RecF pathway recombination
EHC68_RS02930	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EHC68_RS02935	COG0736	holo-[acyl-carrier-protein] synthase activity
EHC68_RS02945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHC68_RS02955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHC68_RS02960	COG3956	TIGRFAM MazG family protein
EHC68_RS02965	COG0504	CTP synthase activity
EHC68_RS02970	COG0148	phosphopyruvate hydratase activity
EHC68_RS02975	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EHC68_RS02980	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EHC68_RS02985	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EHC68_RS02990	COG0585	pseudouridine synthase activity
EHC68_RS02995	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EHC68_RS03000	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EHC68_RS03015	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EHC68_RS03020	COG1546	Belongs to the CinA family
EHC68_RS03025	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EHC68_RS03030	COG2137	regulation of response to DNA damage stimulus
EHC68_RS03035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHC68_RS03040	COG0527	aspartate kinase activity
EHC68_RS03100	COG3630	sodium ion export across plasma membrane
EHC68_RS03105	COG0511	ligase activity, forming carbon-carbon bonds
EHC68_RS03105	COG5016	pyruvate
EHC68_RS03110	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EHC68_RS03115	COG1063	alcohol dehydrogenase
EHC68_RS03120	COG1238	metal cluster binding
EHC68_RS03125	COG0612	Peptidase, M16
EHC68_RS03130	COG2918	glutathione biosynthetic process
EHC68_RS03140	COG1854	S-ribosylhomocysteine lyase activity
EHC68_RS03145	COG4536	flavin adenine dinucleotide binding
EHC68_RS03150	COG4137	Cytochrome C assembly protein
EHC68_RS03155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EHC68_RS03160	COG0228	four-way junction DNA binding
EHC68_RS03165	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EHC68_RS03170	COG0336	Belongs to the RNA methyltransferase TrmD family
EHC68_RS03175	COG0335	large ribosomal subunit rRNA binding
EHC68_RS03180	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EHC68_RS03185	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EHC68_RS03190	COG0237	dephospho-CoA kinase activity
EHC68_RS03200	COG1459	type II secretion system
EHC68_RS03205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC68_RS03215	COG0157	Belongs to the NadC ModD family
EHC68_RS03255	COG0288	reversible hydration of carbon dioxide
EHC68_RS03260	COG0659	secondary active sulfate transmembrane transporter activity
EHC68_RS03270	COG1131	(ABC) transporter
EHC68_RS03275	COG0842	Transport permease protein
EHC68_RS03280	COG1560	Kdo2-lipid A biosynthetic process
EHC68_RS03290	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EHC68_RS03295	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EHC68_RS03300	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHC68_RS03315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC68_RS03325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EHC68_RS03330	COG1489	DNA binding
EHC68_RS03335	COG1643	Atp-dependent helicase
EHC68_RS03340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EHC68_RS03345	COG1752	Esterase of the alpha-beta hydrolase superfamily
EHC68_RS03350	COG1049	propionate catabolic process, 2-methylcitrate cycle
EHC68_RS03355	COG3112	Uncharacterised protein family (UPF0231)
EHC68_RS03365	COG0004	ammonium transporteR
EHC68_RS03370	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC68_RS03380	COG3842	ATPase activity
EHC68_RS03385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC68_RS03400	COG2971	BadF BadG BcrA BcrD
EHC68_RS03410	COG4608	Belongs to the ABC transporter superfamily
EHC68_RS03415	COG0444	Belongs to the ABC transporter superfamily
EHC68_RS03420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC68_RS03430	COG0747	negative chemotaxis
EHC68_RS03435	COG2198	Histidine kinase
EHC68_RS03435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_RS03435	COG0784	Response regulator, receiver
EHC68_RS03435	COG2205	protein histidine kinase activity
EHC68_RS03440	COG2813	Specifically methylates the guanine in position
EHC68_RS03445	COG0628	permease
EHC68_RS03450	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EHC68_RS03455	COG0316	Belongs to the HesB IscA family
EHC68_RS03465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC68_RS03470	COG0739	heme binding
EHC68_RS03475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHC68_RS03485	COG2027	D-alanyl-D-alanine carboxypeptidase
EHC68_RS03490	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EHC68_RS03495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC68_RS03500	COG1534	Rna-binding protein
EHC68_RS03505	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EHC68_RS03510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHC68_RS03515	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EHC68_RS03520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC68_RS03530	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EHC68_RS03545	COG0779	Required for maturation of 30S ribosomal subunits
EHC68_RS03550	COG0195	Participates in both transcription termination and antitermination
EHC68_RS03555	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EHC68_RS03560	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EHC68_RS03565	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EHC68_RS03570	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EHC68_RS03575	COG1185	polyribonucleotide nucleotidyltransferase activity
EHC68_RS03590	COG0534	Mate efflux family protein
EHC68_RS03615	COG3153	acetyltransferase
EHC68_RS03635	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EHC68_RS03645	COG0084	hydrolase, TatD family'
EHC68_RS03650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC68_RS03655	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EHC68_RS03660	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EHC68_RS03665	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EHC68_RS03670	COG0813	purine-nucleoside phosphorylase activity
EHC68_RS03680	COG0560	Phosphoserine phosphatase
EHC68_RS03690	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EHC68_RS03695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC68_RS03700	COG0583	DNA-binding transcription factor activity
EHC68_RS03710	COG1022	Amp-dependent synthetase and ligase
EHC68_RS03715	COG2169	Transcriptional regulator
EHC68_RS03740	COG4964	Belongs to the GSP D family
EHC68_RS03800	COG0583	DNA-binding transcription factor activity
EHC68_RS03805	COG0531	amino acid
EHC68_RS03810	COG2731	YhcH YjgK YiaL family protein
EHC68_RS03815	COG3250	beta-galactosidase activity
EHC68_RS03820	COG1609	Transcriptional regulator
EHC68_RS03840	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EHC68_RS03845	COG2017	converts alpha-aldose to the beta-anomer
EHC68_RS03860	COG2211	Major facilitator Superfamily
EHC68_RS03865	COG1609	Transcriptional regulator
EHC68_RS03870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC68_RS03885	COG0598	Magnesium transport protein CorA
EHC68_RS03890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EHC68_RS03895	COG1349	DNA-binding transcription factor activity
EHC68_RS03900	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EHC68_RS03905	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EHC68_RS03920	COG2271	Major facilitator Superfamily
EHC68_RS03925	COG0584	glycerophosphoryl diester phosphodiesterase
EHC68_RS03930	COG2171	N-acyltransferase activity
EHC68_RS03935	COG3141	response to X-ray
EHC68_RS03955	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EHC68_RS03960	COG1074	ATP-dependent DNA helicase activity
EHC68_RS03965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EHC68_RS03975	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EHC68_RS03975	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EHC68_RS03985	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EHC68_RS03990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EHC68_RS03995	COG2166	iron-sulfur cluster assembly
EHC68_RS04005	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EHC68_RS04010	COG0693	protein deglycase activity
EHC68_RS04015	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHC68_RS04040	COG1595	DNA-templated transcription, initiation
EHC68_RS04060	COG3056	Lipoprotein
EHC68_RS04065	COG2813	Specifically methylates the guanine in position
EHC68_RS04070	COG0271	Belongs to the BolA IbaG family
EHC68_RS04075	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC68_RS04080	COG1805	sodium ion transport
EHC68_RS04085	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC68_RS04090	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC68_RS04095	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC68_RS04100	COG2871	sodium ion transport
EHC68_RS04120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHC68_RS04125	COG0514	ATP-dependent DNA helicase (RecQ)
EHC68_RS04130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC68_RS04145	COG0733	neurotransmitter:sodium symporter activity
EHC68_RS04165	COG0442	prolyl-tRNA aminoacylation
EHC68_RS04170	COG1720	tRNA m6t6A37 methyltransferase activity
EHC68_RS04175	COG0254	rRNA binding
EHC68_RS04190	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EHC68_RS04195	COG1671	Belongs to the UPF0178 family
EHC68_RS04220	COG3098	single-species biofilm formation
EHC68_RS04225	COG0564	pseudouridine synthase activity
EHC68_RS04235	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EHC68_RS04240	COG0024	Methionine aminopeptidase
EHC68_RS04245	COG0052	Belongs to the universal ribosomal protein uS2 family
EHC68_RS04250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EHC68_RS04255	COG0528	UMP kinase activity
EHC68_RS04260	COG0233	cytoplasmic translational termination
EHC68_RS04265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EHC68_RS04270	COG0575	Belongs to the CDS family
EHC68_RS04275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EHC68_RS04280	COG0750	zinc metalloprotease
EHC68_RS04290	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EHC68_RS04295	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC68_RS04300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC68_RS04305	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC68_RS04310	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC68_RS04315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHC68_RS04320	COG0587	DNA-directed DNA polymerase activity
EHC68_RS04325	COG0825	malonyl-CoA metabolic process
EHC68_RS04330	COG0037	tRNA processing
EHC68_RS04340	COG0347	Belongs to the P(II) protein family
EHC68_RS04345	COG3021	interspecies interaction between organisms
EHC68_RS04355	COG1388	LysM domain
EHC68_RS04355	COG0741	lytic transglycosylase activity
EHC68_RS04360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHC68_RS04365	COG2226	methyltransferase
EHC68_RS04370	COG0328	RNA-DNA hybrid ribonuclease activity
EHC68_RS04375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EHC68_RS04390	COG1960	acyl-CoA dehydrogenase activity
EHC68_RS04395	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EHC68_RS04400	COG0121	glutamine amidotransferase
EHC68_RS04405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EHC68_RS04410	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EHC68_RS04415	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EHC68_RS04420	COG2233	PERMEase
EHC68_RS04440	COG1393	Belongs to the ArsC family
EHC68_RS04445	COG4783	chaperone-mediated protein folding
EHC68_RS04460	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EHC68_RS04465	COG2716	regulation of RNA biosynthetic process
EHC68_RS04470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHC68_RS04490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC68_RS04495	COG1393	Belongs to the ArsC family
EHC68_RS04525	COG2837	iron assimilation
EHC68_RS04530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_RS04540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_RS04545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_RS04550	COG1334	flagellar protein FlaG
EHC68_RS04555	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHC68_RS04565	COG1516	flagellar protein fliS
EHC68_RS04575	COG4191	Histidine kinase
EHC68_RS04580	COG2204	response regulator
EHC68_RS04585	COG1677	Flagellar hook-basal body complex protein FliE
EHC68_RS04595	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC68_RS04645	COG1987	bacterial-type flagellum assembly
EHC68_RS04650	COG1684	flagellar biosynthetic protein fliR
EHC68_RS04670	COG0455	bacterial-type flagellum organization
EHC68_RS04685	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EHC68_RS04690	COG2198	Histidine kinase
EHC68_RS04690	COG0643	Histidine kinase
EHC68_RS04695	COG2201	protein-glutamate methylesterase activity
EHC68_RS04700	COG1192	Involved in chromosome partitioning
EHC68_RS04710	COG0835	chemotaxis
EHC68_RS04720	COG4133	protoheme IX ABC transporter activity
EHC68_RS04725	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC68_RS04730	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC68_RS04735	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC68_RS04740	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EHC68_RS04745	COG1138	Cytochrome C-type biogenesis protein
EHC68_RS04750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EHC68_RS04765	COG2853	Lipoprotein
EHC68_RS04775	COG2067	long-chain fatty acid transport protein
EHC68_RS04790	COG0183	Belongs to the thiolase family
EHC68_RS04795	COG1250	3-hydroxyacyl-CoA dehydrogenase
EHC68_RS04795	COG1024	Enoyl-CoA hydratase
EHC68_RS04810	COG2062	phosphohistidine phosphatase, SixA
EHC68_RS04815	COG2840	Smr protein MutS2
EHC68_RS04820	COG2890	protein-(glutamine-N5) methyltransferase activity
EHC68_RS04825	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EHC68_RS04830	COG2860	membrane
EHC68_RS04840	COG3101	peptidyl-lysine hydroxylation
EHC68_RS04855	COG0431	NADPH-dependent FMN reductase
EHC68_RS04860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC68_RS04860	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EHC68_RS04865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EHC68_RS04870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC68_RS04875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHC68_RS04885	COG0101	tRNA pseudouridine synthase activity
EHC68_RS04890	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHC68_RS04895	COG0285	dihydrofolate synthase activity
EHC68_RS04905	COG1286	toxin biosynthetic process
EHC68_RS04910	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EHC68_RS04915	COG0583	DNA-binding transcription factor activity
EHC68_RS04920	COG0745	RESPONSE REGULATOR receiver
EHC68_RS04930	COG2832	Protein of unknown function (DUF454)
EHC68_RS04935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHC68_RS04945	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EHC68_RS04950	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EHC68_RS04955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EHC68_RS04960	COG0814	amino acid
EHC68_RS04965	COG0251	oxidation-reduction process
EHC68_RS04970	COG3681	Belongs to the UPF0597 family
EHC68_RS04985	COG2261	transglycosylase associated protein
EHC68_RS04990	COG2983	Belongs to the UPF0260 family
EHC68_RS04995	COG0668	transmembrane transport
EHC68_RS05000	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EHC68_RS05005	COG0346	lactoylglutathione lyase activity
EHC68_RS05015	COG1785	Belongs to the alkaline phosphatase family
EHC68_RS05035	COG2226	methyltransferase
EHC68_RS05050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC68_RS05055	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC68_RS05065	COG3139	Protein of unknown function (DUF1315)
EHC68_RS05070	COG0252	asparaginase activity
EHC68_RS05075	COG0616	signal peptide processing
EHC68_RS05080	COG1902	pentaerythritol trinitrate reductase activity
EHC68_RS05080	COG0446	pyridine nucleotide-disulphide oxidoreductase
EHC68_RS05090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC68_RS05110	COG0123	including yeast histone deacetylase and acetoin utilization protein
EHC68_RS05160	COG3083	sulfuric ester hydrolase activity
EHC68_RS05165	COG3082	Protein of unknown function (DUF1414)
EHC68_RS05170	COG3081	Nucleoid-associated protein
EHC68_RS05185	COG1757	Na H antiporter
EHC68_RS05190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHC68_RS05195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC68_RS05200	COG2095	MarC family integral membrane protein
EHC68_RS05205	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_RS05205	COG1454	alcohol dehydrogenase
EHC68_RS05225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EHC68_RS05235	COG2056	Na+-H+ antiporter family
EHC68_RS05240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EHC68_RS05255	COG2885	chlorophyll binding
EHC68_RS05265	COG0346	lactoylglutathione lyase activity
EHC68_RS05270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EHC68_RS05275	COG4660	Part of a membrane complex involved in electron transport
EHC68_RS05280	COG4659	FMN binding
EHC68_RS05285	COG4658	electron transport chain
EHC68_RS05290	COG4656	Part of a membrane complex involved in electron transport
EHC68_RS05295	COG2878	Part of a membrane complex involved in electron transport
EHC68_RS05300	COG4657	Part of a membrane complex involved in electron transport
EHC68_RS05315	COG0556	nucleotide-excision repair
EHC68_RS05320	COG2204	response regulator
EHC68_RS05325	COG2198	Histidine kinase
EHC68_RS05330	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EHC68_RS05335	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHC68_RS05340	COG0521	Mo-molybdopterin cofactor biosynthetic process
EHC68_RS05345	COG0315	cyclic pyranopterin monophosphate synthase activity
EHC68_RS05350	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EHC68_RS05355	COG0314	molybdopterin synthase activity
EHC68_RS05365	COG0601	transmembrane transport
EHC68_RS05370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC68_RS05375	COG0444	Belongs to the ABC transporter superfamily
EHC68_RS05385	COG0435	Glutathione S-transferase
EHC68_RS05395	COG3174	membrane
EHC68_RS05400	COG0280	phosphate acetyltransferase
EHC68_RS05400	COG0857	belongs to the CobB CobQ family
EHC68_RS05405	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHC68_RS05410	COG3092	negative regulation of chromosome organization
EHC68_RS05420	COG4120	Belongs to the binding-protein-dependent transport system permease family
EHC68_RS05425	COG1122	ATPase activity
EHC68_RS05430	COG0366	Alpha amylase catalytic
EHC68_RS05435	COG3706	GGDEF domain
EHC68_RS05435	COG0745	RESPONSE REGULATOR receiver
EHC68_RS05440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC68_RS05445	COG3318	Belongs to the UPF0149 family
EHC68_RS05445	COG3012	SEC-C Motif Domain Protein
EHC68_RS05450	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EHC68_RS05455	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC68_RS05460	COG2186	Transcriptional regulator
EHC68_RS05470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC68_RS05470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC68_RS05480	COG0572	uridine kinase
EHC68_RS05490	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EHC68_RS05495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHC68_RS05500	COG0659	secondary active sulfate transmembrane transporter activity
EHC68_RS05505	COG1530	ribonuclease E activity
EHC68_RS05510	COG0564	pseudouridine synthase activity
EHC68_RS05515	COG0424	maF-like protein
EHC68_RS05520	COG1399	metal-binding, possibly nucleic acid-binding protein
EHC68_RS05530	COG0416	fatty acid biosynthetic process
EHC68_RS05535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHC68_RS05565	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHC68_RS05570	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EHC68_RS05580	COG0084	hydrolase, TatD family'
EHC68_RS05585	COG1263	PTS System
EHC68_RS05585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC68_RS05605	COG0733	neurotransmitter:sodium symporter activity
EHC68_RS05620	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC68_RS05625	COG0469	pyruvate kinase activity
EHC68_RS05630	COG1940	carbohydrate kinase activity
EHC68_RS05635	COG0784	Response regulator, receiver
EHC68_RS05635	COG0835	chemotaxis
EHC68_RS05640	COG0587	DNA-directed DNA polymerase activity
EHC68_RS05655	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_RS05660	COG0616	signal peptide processing
EHC68_RS05665	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EHC68_RS05670	COG0539	negative regulation of cytoplasmic translation
EHC68_RS05680	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EHC68_RS05685	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EHC68_RS05690	COG0284	orotidine-5'-phosphate decarboxylase activity
EHC68_RS05695	COG4166	transmembrane transport
EHC68_RS05720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EHC68_RS05730	COG3008	intermembrane lipid transfer
EHC68_RS05730	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EHC68_RS05735	COG2995	paraquat-inducible protein a
EHC68_RS05740	COG3258	Cytochrome c
EHC68_RS05745	COG2863	cytochrome
EHC68_RS05785	COG4232	protein-disulfide reductase activity
EHC68_RS05790	COG3118	belongs to the thioredoxin family
EHC68_RS05810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_RS05820	COG0577	efflux transmembrane transporter activity
EHC68_RS05820	COG1136	(ABC) transporter
EHC68_RS05830	COG0577	efflux transmembrane transporter activity
EHC68_RS05830	COG1136	(ABC) transporter
EHC68_RS05835	COG1335	isochorismatase
EHC68_RS05850	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHC68_RS05885	COG3850	Histidine kinase
EHC68_RS05885	COG5002	protein histidine kinase activity
EHC68_RS05890	COG0745	RESPONSE REGULATOR receiver
EHC68_RS05900	COG0840	transmembrane signaling receptor activity
EHC68_RS05905	COG1032	radical SAM domain protein
EHC68_RS05910	COG5001	Diguanylate cyclase
EHC68_RS05910	COG4251	negative regulation of phosphorylation
EHC68_RS05910	COG3706	GGDEF domain
EHC68_RS05910	COG2203	Gaf domain
EHC68_RS05925	COG0583	DNA-binding transcription factor activity
EHC68_RS05935	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHC68_RS05945	COG2350	Protein conserved in bacteria
EHC68_RS05950	COG1607	acyl-coa hydrolase
EHC68_RS05955	COG2917	probably involved in intracellular septation
EHC68_RS05975	COG1301	dicarboxylic acid transport
EHC68_RS05985	COG0318	PFAM AMP-dependent synthetase and ligase
EHC68_RS05990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC68_RS05995	COG0159	tryptophan synthase activity
EHC68_RS06000	COG0133	tryptophan synthase activity
EHC68_RS06005	COG0135	phosphoribosylanthranilate isomerase activity
EHC68_RS06005	COG0134	indole-3-glycerol-phosphate synthase activity
EHC68_RS06010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHC68_RS06015	COG0512	Glutamine amidotransferase of anthranilate synthase
EHC68_RS06020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHC68_RS06030	COG0613	PHP domain protein
EHC68_RS06035	COG0009	L-threonylcarbamoyladenylate synthase
EHC68_RS06045	COG1187	pseudouridine synthase activity
EHC68_RS06055	COG3099	Belongs to the UPF0263 family
EHC68_RS06060	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHC68_RS06070	COG0417	DNA replication proofreading
EHC68_RS06075	COG2197	response regulator
EHC68_RS06080	COG0322	excinuclease ABC activity
EHC68_RS06120	COG0019	diaminopimelate decarboxylase activity
EHC68_RS06145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHC68_RS06150	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHC68_RS06155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC68_RS06175	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EHC68_RS06185	COG0437	4 iron, 4 sulfur cluster binding
EHC68_RS06190	COG3301	Polysulphide reductase, NrfD
EHC68_RS06195	COG1138	Cytochrome C-type biogenesis protein
EHC68_RS06205	COG3088	subunit of a heme lyase
EHC68_RS06205	COG4235	cytochrome complex assembly
EHC68_RS06215	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC68_RS06240	COG2989	Protein conserved in bacteria
EHC68_RS06245	COG3108	Peptidase M15
EHC68_RS06250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHC68_RS06265	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EHC68_RS06290	COG1846	Transcriptional regulator
EHC68_RS06295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC68_RS06300	COG0840	transmembrane signaling receptor activity
EHC68_RS06320	COG1448	Aminotransferase
EHC68_RS06345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC68_RS06355	COG0017	Asparaginyl-tRNA synthetase
EHC68_RS06365	COG0720	synthase
EHC68_RS06375	COG2200	EAL domain
EHC68_RS06380	COG1760	l-serine dehydratase
EHC68_RS06385	COG0814	amino acid
EHC68_RS06390	COG0494	nUDIX hydrolase
EHC68_RS06400	COG0784	Response regulator, receiver
EHC68_RS06400	COG2205	protein histidine kinase activity
EHC68_RS06405	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHC68_RS06425	COG3106	COG3106 Predicted ATPase
EHC68_RS06430	COG3768	UPF0283 membrane protein
EHC68_RS06440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC68_RS06580	COG0494	nUDIX hydrolase
EHC68_RS06655	COG1280	lysine exporter protein (LysE YggA)
EHC68_RS06855	COG0251	oxidation-reduction process
EHC68_RS07045	COG1335	isochorismatase
EHC68_RS07085	COG0494	nUDIX hydrolase
EHC68_RS07165	COG1280	lysine exporter protein (LysE YggA)
EHC68_RS07380	COG1683	Conserved Protein
EHC68_RS07440	COG0346	lactoylglutathione lyase activity
EHC68_RS07450	COG0546	phosphoglycolate phosphatase activity
EHC68_RS07715	COG1757	Na H antiporter
EHC68_RS07720	COG0174	glutamine synthetase
EHC68_RS07730	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EHC68_RS07735	COG1396	sequence-specific DNA binding
EHC68_RS07735	COG1917	Cupin 2, conserved barrel domain protein
EHC68_RS07740	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_RS07745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC68_RS07755	COG2957	Belongs to the agmatine deiminase family
EHC68_RS07760	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_RS07765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHC68_RS07770	COG1227	inorganic diphosphatase activity
EHC68_RS07780	COG2200	EAL domain
EHC68_RS07780	COG2771	luxR family
EHC68_RS07790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHC68_RS07805	COG1846	Transcriptional regulator
EHC68_RS07810	COG2315	Protein conserved in bacteria
EHC68_RS07830	COG0110	maltose O-acetyltransferase activity
EHC68_RS07845	COG5002	protein histidine kinase activity
EHC68_RS07845	COG0784	Response regulator, receiver
EHC68_RS07845	COG2205	protein histidine kinase activity
EHC68_RS07860	COG3063	Type IV pilus biogenesis stability protein PilW
EHC68_RS07865	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EHC68_RS07880	COG0531	amino acid
EHC68_RS07890	COG1560	Kdo2-lipid A biosynthetic process
EHC68_RS07900	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EHC68_RS07930	COG3706	GGDEF domain
EHC68_RS07985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHC68_RS07990	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHC68_RS08030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EHC68_RS08110	COG3550	peptidyl-serine autophosphorylation
EHC68_RS08115	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EHC68_RS08120	COG1280	lysine exporter protein (LysE YggA)
EHC68_RS08130	COG1115	amino acid carrier protein
EHC68_RS08155	COG1368	sulfuric ester hydrolase activity
EHC68_RS08160	COG0642	Histidine kinase
EHC68_RS08165	COG0745	RESPONSE REGULATOR receiver
EHC68_RS08175	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_RS08195	COG2113	Glycine betaine
EHC68_RS08200	COG4176	ABC-type proline glycine betaine transport system permease component
EHC68_RS08220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC68_RS08225	COG0456	acetyltransferase
EHC68_RS08230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHC68_RS08235	COG0662	Cupin 2, conserved barrel domain protein
EHC68_RS08240	COG0527	aspartate kinase activity
EHC68_RS08260	COG1858	cytochrome C peroxidase
EHC68_RS08275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_RS08290	COG3290	protein histidine kinase activity
EHC68_RS08295	COG4565	transcriptional regulatory protein
EHC68_RS08300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EHC68_RS08305	COG0363	glucosamine-6-phosphate deaminase activity
EHC68_RS08310	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EHC68_RS08330	COG3284	Transcriptional regulator
EHC68_RS08335	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_RS08405	COG4669	(LipO)protein
EHC68_RS08425	COG3177	Filamentation induced by cAMP protein fic
EHC68_RS08465	COG1073	alpha beta
EHC68_RS08470	COG1073	alpha beta
EHC68_RS08480	COG4792	protein secretion
EHC68_RS08485	COG4791	protein targeting
EHC68_RS08490	COG4794	Type iii secretion
EHC68_RS08495	COG4790	Type iii secretion
EHC68_RS08500	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC68_RS08565	COG0457	Tetratricopeptide repeat
EHC68_RS08585	COG0730	response to heat
EHC68_RS08615	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EHC68_RS08620	COG0372	Belongs to the citrate synthase family
EHC68_RS08630	COG2828	Protein conserved in bacteria
EHC68_RS08655	COG0561	phosphatase activity
EHC68_RS08660	COG0602	queuosine metabolic process
EHC68_RS08665	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EHC68_RS08670	COG3706	GGDEF domain
EHC68_RS08710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EHC68_RS08715	COG0840	transmembrane signaling receptor activity
EHC68_RS08720	COG1254	Belongs to the acylphosphatase family
EHC68_RS08725	COG2920	part of a sulfur-relay system
EHC68_RS08735	COG0670	Belongs to the BI1 family
EHC68_RS08740	COG1126	abc transporter atp-binding protein
EHC68_RS08745	COG0765	amino acid transport
EHC68_RS08755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_RS08770	COG1666	GTP binding
EHC68_RS08775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC68_RS08795	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EHC68_RS08795	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHC68_RS08800	COG3008	intermembrane lipid transfer
EHC68_RS08805	COG2995	paraquat-inducible protein a
EHC68_RS08810	COG1132	(ABC) transporter
EHC68_RS08815	COG1956	GAF domain-containing protein
EHC68_RS08820	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EHC68_RS08835	COG0308	aminopeptidase N
EHC68_RS08845	COG2902	Dehydrogenase
EHC68_RS08850	COG0167	dihydroorotate dehydrogenase activity
EHC68_RS08865	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EHC68_RS08865	COG0116	Belongs to the methyltransferase superfamily
EHC68_RS08890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC68_RS08895	COG1067	ATP-dependent peptidase activity
EHC68_RS08900	COG3120	sequence-specific DNA binding
EHC68_RS08950	COG3278	Belongs to the heme-copper respiratory oxidase family
EHC68_RS08965	COG2010	Cytochrome c
EHC68_RS08975	COG2217	Heavy metal translocating P-type atpase
EHC68_RS08990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC68_RS08995	COG0589	response to stress
EHC68_RS09005	COG0037	tRNA processing
EHC68_RS09025	COG3842	ATPase activity
EHC68_RS09030	COG1176	ABC-type spermidine putrescine transport system, permease component I
EHC68_RS09035	COG1177	transmembrane transport
EHC68_RS09040	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC68_RS09045	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC68_RS09050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EHC68_RS09060	COG0004	ammonium transporteR
EHC68_RS09085	COG0437	4 iron, 4 sulfur cluster binding
EHC68_RS09090	COG0243	molybdopterin cofactor binding
EHC68_RS09090	COG3383	formate dehydrogenase (NAD+) activity
EHC68_RS09100	COG3381	protein complex oligomerization
EHC68_RS09125	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHC68_RS09130	COG0488	(ABC) transporter
EHC68_RS09140	COG4191	Histidine kinase
EHC68_RS09145	COG2204	response regulator
EHC68_RS09165	COG3842	ATPase activity
EHC68_RS09170	COG0746	molybdenum cofactor guanylyltransferase activity
EHC68_RS09175	COG0303	'Molybdopterin
EHC68_RS09185	COG1940	carbohydrate kinase activity
EHC68_RS09230	COG0791	NLP P60 protein
EHC68_RS09240	COG3706	GGDEF domain
EHC68_RS09245	COG2201	protein-glutamate methylesterase activity
EHC68_RS09260	COG0307	riboflavin synthase, alpha
EHC68_RS09265	COG0534	Mate efflux family protein
EHC68_RS09275	COG1793	dna ligase
EHC68_RS09310	COG2204	response regulator
EHC68_RS09320	COG0438	transferase activity, transferring glycosyl groups
EHC68_RS09355	COG0438	transferase activity, transferring glycosyl groups
EHC68_RS09360	COG1215	transferase activity, transferring glycosyl groups
EHC68_RS09365	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EHC68_RS09375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC68_RS09395	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHC68_RS09410	COG3302	dmso reductase anchor subunit
EHC68_RS09415	COG0437	4 iron, 4 sulfur cluster binding
EHC68_RS09420	COG0243	molybdopterin cofactor binding
EHC68_RS09460	COG0443	Heat shock 70 kDa protein
EHC68_RS09465	COG0443	Heat shock 70 kDa protein
EHC68_RS09495	COG1132	(ABC) transporter
EHC68_RS09500	COG1132	(ABC) transporter
EHC68_RS09525	COG0814	amino acid
EHC68_RS09540	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EHC68_RS09620	COG1522	sequence-specific DNA binding
EHC68_RS09655	COG0515	serine threonine protein kinase
EHC68_RS09680	COG3501	Rhs element vgr protein
EHC68_RS09720	COG0739	heme binding
EHC68_RS09730	COG0861	Integral membrane protein TerC family
EHC68_RS09740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC68_RS09745	COG1328	CTP reductase activity
EHC68_RS09750	COG1280	lysine exporter protein (LysE YggA)
EHC68_RS09760	COG3300	MHYT domain
EHC68_RS09760	COG5001	Diguanylate cyclase
EHC68_RS09770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_RS09770	COG4191	Histidine kinase
EHC68_RS09775	COG0471	metal ion transport
EHC68_RS09810	COG0583	DNA-binding transcription factor activity
EHC68_RS09815	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EHC68_RS09885	COG0758	DNA mediated transformation
EHC68_RS10015	COG1783	phage Terminase large subunit
EHC68_RS10185	COG0625	glutathione transferase activity
EHC68_RS10195	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EHC68_RS10205	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC68_RS10215	COG0601	transmembrane transport
EHC68_RS10220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC68_RS10225	COG0444	Belongs to the ABC transporter superfamily
EHC68_RS10245	COG3291	Pkd domain containing protein
EHC68_RS10255	COG1177	transmembrane transport
EHC68_RS10260	COG1176	ABC-type spermidine putrescine transport system, permease component I
EHC68_RS10265	COG3842	ATPase activity
EHC68_RS10270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHC68_RS10275	COG2423	ornithine cyclodeaminase activity
EHC68_RS10295	COG3938	Belongs to the proline racemase family
EHC68_RS10325	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EHC68_RS10330	COG1451	nucleotide metabolic process
EHC68_RS10340	COG0583	DNA-binding transcription factor activity
EHC68_RS10360	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
EHC68_RS10365	COG4139	cobalamin transport
EHC68_RS10370	COG2988	succinylglutamate desuccinylase activity
EHC68_RS10385	COG2062	phosphohistidine phosphatase, SixA
EHC68_RS10395	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EHC68_RS10400	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EHC68_RS10405	COG0702	epimerase
EHC68_RS10415	COG2925	Exonuclease
EHC68_RS10420	COG1380	Effector of murein hydrolase LrgA
EHC68_RS10425	COG1346	cytolysis
EHC68_RS10430	COG0295	cytidine deaminase activity
EHC68_RS10435	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EHC68_RS10440	COG0500	methyltransferase
EHC68_RS10450	COG0776	regulation of translation
EHC68_RS10465	COG0072	phenylalanine-tRNA ligase activity
EHC68_RS10465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC68_RS10470	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EHC68_RS10475	COG3706	GGDEF domain
EHC68_RS10505	COG0393	Putative heavy-metal-binding
EHC68_RS10515	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EHC68_RS10525	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHC68_RS10540	COG2188	Transcriptional regulator
EHC68_RS10545	COG1228	amidohydrolase
EHC68_RS10550	COG0010	Belongs to the arginase family
EHC68_RS10555	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EHC68_RS10560	COG2986	histidine ammonia-lyase
EHC68_RS10575	COG0277	FAD linked oxidase domain protein
EHC68_RS10575	COG0247	lactate metabolic process
EHC68_RS10610	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EHC68_RS10625	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EHC68_RS10630	COG1643	Atp-dependent helicase
EHC68_RS10635	COG0281	malic enzyme
EHC68_RS10640	COG2949	membrane
EHC68_RS10645	COG0471	metal ion transport
EHC68_RS10650	COG0745	RESPONSE REGULATOR receiver
EHC68_RS10650	COG3706	GGDEF domain
EHC68_RS10670	COG0492	ferredoxin-NADP+ reductase activity
EHC68_RS10675	COG4988	ABC transporter
EHC68_RS10680	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EHC68_RS10685	COG3048	D-serine ammonia-lyase activity
EHC68_RS10690	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EHC68_RS10700	COG4191	Histidine kinase
EHC68_RS10700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_RS10715	COG3070	regulator of competence-specific genes
EHC68_RS10730	COG2431	L-lysine efflux transmembrane transporter activity
EHC68_RS10740	COG0076	glutamate decarboxylase activity
EHC68_RS10745	COG1737	Transcriptional regulator
EHC68_RS10760	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EHC68_RS10765	COG2985	domain, Protein
EHC68_RS10765	COG3273	potassium ion transport
EHC68_RS10770	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EHC68_RS10785	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC68_RS10800	COG4181	ATPase activity
EHC68_RS10805	COG0534	Mate efflux family protein
EHC68_RS10810	COG0702	epimerase
EHC68_RS10815	COG3005	denitrification pathway
EHC68_RS10845	COG2814	Major facilitator Superfamily
EHC68_RS10850	COG1187	pseudouridine synthase activity
EHC68_RS10855	COG1061	Type III restriction enzyme res subunit
EHC68_RS10865	COG0745	RESPONSE REGULATOR receiver
EHC68_RS10870	COG2205	protein histidine kinase activity
EHC68_RS10875	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EHC68_RS10915	COG3313	Fe-S protein
EHC68_RS10940	COG0493	'glutamate synthase
EHC68_RS10950	COG0398	Pfam SNARE associated Golgi protein
EHC68_RS10955	COG4134	Bacterial extracellular solute-binding protein
EHC68_RS10960	COG4135	transport system, permease component
EHC68_RS10965	COG4136	ATPase activity
EHC68_RS10970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHC68_RS10985	COG3604	Transcriptional regulator
EHC68_RS10990	COG1151	hydroxylamine reductase activity
EHC68_RS10995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC68_RS11005	COG0564	pseudouridine synthase activity
EHC68_RS11015	COG0733	neurotransmitter:sodium symporter activity
EHC68_RS11025	COG0626	cystathionine gamma-synthase activity
EHC68_RS11030	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EHC68_RS11035	COG5380	lipid catabolic process
EHC68_RS11040	COG2818	Glycosylase
EHC68_RS11055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_RS11060	COG1983	PspC domain protein
EHC68_RS11070	COG1842	Phage shock protein A
EHC68_RS11075	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EHC68_RS11085	COG4168	peptide transport system, permease
EHC68_RS11090	COG4171	peptide transport system, permease
EHC68_RS11100	COG4172	Belongs to the ABC transporter superfamily
EHC68_RS11110	COG1227	inorganic diphosphatase activity
EHC68_RS11125	COG0243	molybdopterin cofactor binding
EHC68_RS11130	COG3005	denitrification pathway
EHC68_RS11135	COG4459	periplasmic nitrate reductase
EHC68_RS11140	COG0390	transport system, permease component
EHC68_RS11150	COG2116	formate transmembrane transporter activity
EHC68_RS11175	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EHC68_RS11180	COG1435	thymidine kinase activity
EHC68_RS11185	COG0215	cysteine-tRNA ligase activity
EHC68_RS11190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHC68_RS11195	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC68_RS11200	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EHC68_RS11210	COG3012	SEC-C Motif Domain Protein
EHC68_RS11215	COG0140	phosphoribosyl-ATP diphosphatase activity
EHC68_RS11215	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EHC68_RS11220	COG0107	imidazoleglycerol-phosphate synthase activity
EHC68_RS11225	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EHC68_RS11230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EHC68_RS11235	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EHC68_RS11235	COG0131	Imidazoleglycerol-phosphate dehydratase
EHC68_RS11240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EHC68_RS11245	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EHC68_RS11250	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EHC68_RS11265	COG1757	Na H antiporter
EHC68_RS11275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC68_RS11285	COG0482	sulfurtransferase activity
EHC68_RS11290	COG2915	High frequency lysogenization protein hflD homolog
EHC68_RS11295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EHC68_RS11320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EHC68_RS11335	COG0300	oxidoreductase activity
EHC68_RS11345	COG0501	Belongs to the peptidase M48B family
EHC68_RS11355	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EHC68_RS11365	COG0156	8-amino-7-oxononanoate synthase activity
EHC68_RS11370	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EHC68_RS11375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EHC68_RS11380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EHC68_RS11390	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EHC68_RS11395	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EHC68_RS11400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EHC68_RS11405	COG1674	ftsk spoiiie
EHC68_RS11415	COG0686	Belongs to the AlaDH PNT family
EHC68_RS11425	COG0583	DNA-binding transcription factor activity
EHC68_RS11440	COG3568	Endonuclease Exonuclease Phosphatase
EHC68_RS11470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC68_RS11475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_RS11490	COG0840	transmembrane signaling receptor activity
EHC68_RS11560	COG5002	protein histidine kinase activity
EHC68_RS11560	COG0784	Response regulator, receiver
EHC68_RS11570	COG0754	glutathionylspermidine amidase activity
EHC68_RS11580	COG3766	membrane
EHC68_RS11590	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EHC68_RS11595	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EHC68_RS11600	COG2885	chlorophyll binding
EHC68_RS11605	COG0823	Involved in the tonB-independent uptake of proteins
EHC68_RS11620	COG0811	peptide transport
EHC68_RS11625	COG0824	Thioesterase
EHC68_RS11635	COG4890	Cyd operon protein YbgT
EHC68_RS11640	COG1294	oxidase, subunit
EHC68_RS11645	COG1271	oxidase subunit
EHC68_RS11650	COG2255	four-way junction helicase activity
EHC68_RS11655	COG0632	four-way junction helicase activity
EHC68_RS11660	COG0840	transmembrane signaling receptor activity
EHC68_RS11665	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EHC68_RS11670	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EHC68_RS11675	COG1801	Protein of unknown function DUF72
EHC68_RS11680	COG4106	trans-aconitate 2-methyltransferase activity
EHC68_RS11685	COG0500	methyltransferase
EHC68_RS11695	COG0189	ligase activity
EHC68_RS11695	COG4067	protein conserved in archaea
EHC68_RS11715	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EHC68_RS11720	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EHC68_RS11725	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EHC68_RS11730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC68_RS11735	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EHC68_RS11740	COG0745	RESPONSE REGULATOR receiver
EHC68_RS11745	COG3381	protein complex oligomerization
EHC68_RS11750	COG1609	Transcriptional regulator
EHC68_RS11755	COG3070	regulator of competence-specific genes
EHC68_RS11775	COG0297	glycogen (starch) synthase activity
EHC68_RS11780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC68_RS11785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC68_RS11795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EHC68_RS11805	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EHC68_RS11810	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EHC68_RS11815	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EHC68_RS11825	COG0542	response to heat
EHC68_RS11830	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EHC68_RS11835	COG1278	Cold shock
EHC68_RS11845	COG1187	pseudouridine synthase activity
EHC68_RS11850	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC68_RS11860	COG1199	ATP-dependent helicase activity
EHC68_RS11865	COG0730	response to heat
EHC68_RS11870	COG3923	Primosomal replication protein n
EHC68_RS11880	COG0708	Exodeoxyribonuclease III
EHC68_RS11895	COG4215	(ABC) transporter
EHC68_RS11925	COG1882	Formate acetyltransferase
EHC68_RS11935	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC68_RS11945	COG3013	Belongs to the UPF0304 family
EHC68_RS11955	COG2766	serine protein kinase
EHC68_RS11960	COG2718	Belongs to the UPF0229 family
EHC68_RS11965	COG2719	SpoVR family
EHC68_RS11970	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EHC68_RS11980	COG1663	tetraacyldisaccharide 4'-kinase activity
EHC68_RS11985	COG1132	(ABC) transporter
EHC68_RS11990	COG2333	competence protein COMEC
EHC68_RS11990	COG0658	competence protein
EHC68_RS12000	COG4591	ABC-type transport system involved in lipoprotein release permease component
EHC68_RS12005	COG1136	(ABC) transporter
EHC68_RS12010	COG4591	ABC-type transport system involved in lipoprotein release permease component
EHC68_RS12020	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EHC68_RS12035	COG1252	NADH dehydrogenase
EHC68_RS12045	COG3150	esterase
EHC68_RS12070	COG0537	adenosine 5'-monophosphoramidase activity
EHC68_RS12100	COG0516	GMP reductase activity
EHC68_RS12100	COG0517	IMP dehydrogenase activity
EHC68_RS12110	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EHC68_RS12115	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EHC68_RS12120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC68_RS12195	COG2199	diguanylate cyclase activity
EHC68_RS12210	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EHC68_RS12215	COG1946	Acyl-CoA thioesterase
EHC68_RS12225	COG1522	sequence-specific DNA binding
EHC68_RS12255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC68_RS12305	COG0477	Major facilitator Superfamily
EHC68_RS12310	COG2855	membrane
EHC68_RS12325	COG1441	menaquinone biosynthetic process
EHC68_RS12330	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EHC68_RS12335	COG0596	Alpha beta hydrolase
EHC68_RS12340	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EHC68_RS12345	COG1169	isochorismate synthase
EHC68_RS12350	COG0436	Aminotransferase
EHC68_RS12355	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EHC68_RS12360	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EHC68_RS12375	COG1555	photosystem II stabilization
EHC68_RS12380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC68_RS12385	COG0776	regulation of translation
EHC68_RS12390	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EHC68_RS12395	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EHC68_RS12405	COG0544	peptidyl-prolyl cis-trans isomerase activity
EHC68_RS12415	COG2204	response regulator
EHC68_RS12425	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EHC68_RS12430	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EHC68_RS12435	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EHC68_RS12440	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EHC68_RS12460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC68_RS12465	COG0569	domain protein
EHC68_RS12470	COG0513	Belongs to the DEAD box helicase family
EHC68_RS12475	COG1253	flavin adenine dinucleotide binding
EHC68_RS12510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHC68_RS12515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHC68_RS12530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC68_RS12535	COG1216	Glycosyl transferase, family 2
EHC68_RS12540	COG2986	histidine ammonia-lyase
EHC68_RS12565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EHC68_RS12570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC68_RS12575	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_RS12595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EHC68_RS12600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC68_RS12605	COG0583	DNA-binding transcription factor activity
EHC68_RS12610	COG2951	lytic endotransglycosylase activity
EHC68_RS12615	COG3100	YcgL domain-containing protein
EHC68_RS12620	COG0850	regulation of cytokinetic process
EHC68_RS12625	COG2894	cell division
EHC68_RS12630	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EHC68_RS12635	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EHC68_RS12640	COG0318	PFAM AMP-dependent synthetase and ligase
EHC68_RS12645	COG2267	carboxylic ester hydrolase activity
EHC68_RS12660	COG1214	PFAM Peptidase M22, glycoprotease
EHC68_RS12665	COG1199	ATP-dependent helicase activity
EHC68_RS12670	COG0788	formyltetrahydrofolate deformylase activity
EHC68_RS12675	COG3102	Protein conserved in bacteria
EHC68_RS12685	COG0018	arginyl-trna synthetase
EHC68_RS12705	COG1918	ferrous iron import across plasma membrane
EHC68_RS12720	COG4977	sequence-specific DNA binding
EHC68_RS12725	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EHC68_RS12730	COG1121	(ABC) transporter
EHC68_RS12735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EHC68_RS12745	COG0045	succinate-CoA ligase (ADP-forming) activity
EHC68_RS12750	COG0508	dehydrogenase complex catalyzes the overall conversion of
EHC68_RS12755	COG0567	Dehydrogenase, E1 component
EHC68_RS12760	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EHC68_RS12765	COG1053	succinate dehydrogenase
EHC68_RS12770	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EHC68_RS12775	COG2009	succinate dehydrogenase
EHC68_RS12785	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EHC68_RS12795	COG0033	Phosphoglucomutase
EHC68_RS12800	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EHC68_RS12805	COG0596	Alpha beta hydrolase
EHC68_RS12815	COG0716	FMN binding
EHC68_RS12825	COG0735	belongs to the Fur family
EHC68_RS12830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC68_RS12835	COG1263	PTS System
EHC68_RS12835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC68_RS12835	COG2190	(PTS) system
EHC68_RS12845	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EHC68_RS12850	COG1846	Transcriptional regulator
EHC68_RS12850	COG1940	carbohydrate kinase activity
EHC68_RS12855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EHC68_RS12855	COG4651	solute:proton antiporter activity
EHC68_RS12860	COG0367	asparagine synthase
EHC68_RS12865	COG0250	Participates in transcription elongation, termination and antitermination
EHC68_RS12870	COG3104	oligopeptide transport
EHC68_RS12875	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EHC68_RS12880	COG0563	adenylate kinase activity
EHC68_RS12885	COG0326	Molecular chaperone. Has ATPase activity
EHC68_RS12890	COG3710	Transcriptional regulator
EHC68_RS12910	COG0622	Phosphoesterase
EHC68_RS12940	COG1090	epimerase
EHC68_RS12945	COG0300	oxidoreductase activity
EHC68_RS12955	COG3118	belongs to the thioredoxin family
EHC68_RS12960	COG0330	HflC and HflK could
EHC68_RS12985	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHC68_RS12990	COG3115	cell septum assembly
EHC68_RS12995	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EHC68_RS13000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EHC68_RS13010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_RS13015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHC68_RS13020	COG2190	(PTS) system
EHC68_RS13030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_RS13035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_RS13045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_RS13055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_RS13065	COG3951	Flagellar rod assembly protein muramidase FlgJ
EHC68_RS13065	COG1705	Flagellar rod assembly protein muramidase FlgJ
EHC68_RS13070	COG1706	bacterial-type flagellum-dependent cell motility
EHC68_RS13075	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EHC68_RS13080	COG4786	Flagellar basal body rod
EHC68_RS13085	COG4787	bacterial-type flagellum-dependent cell motility
EHC68_RS13095	COG1749	Flagellar hook protein flgE
EHC68_RS13100	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EHC68_RS13105	COG1558	bacterial-type flagellum-dependent cell motility
EHC68_RS13110	COG1815	bacterial-type flagellum-dependent cell motility
EHC68_RS13115	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EHC68_RS13120	COG0835	chemotaxis
EHC68_RS13120	COG0784	Response regulator, receiver
EHC68_RS13180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC68_RS13185	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC68_RS13200	COG2608	mercury ion transmembrane transporter activity
EHC68_RS13200	COG2217	Heavy metal translocating P-type atpase
EHC68_RS13240	COG2840	Smr protein MutS2
EHC68_RS13245	COG1187	pseudouridine synthase activity
EHC68_RS13255	COG0737	Belongs to the 5'-nucleotidase family
EHC68_RS13260	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EHC68_RS13265	COG2912	Transglutaminase-like superfamily
EHC68_RS13270	COG3094	Invasion gene expression up-regulator, SirB
EHC68_RS13275	COG2890	protein-(glutamine-N5) methyltransferase activity
EHC68_RS13280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EHC68_RS13285	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EHC68_RS13295	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EHC68_RS13300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EHC68_RS13305	COG0193	aminoacyl-tRNA hydrolase activity
EHC68_RS13310	COG0012	GTP binding
EHC68_RS13425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC68_RS13435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHC68_RS13440	COG1702	phosphate starvation-inducible protein PhoH
EHC68_RS13445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EHC68_RS13450	COG4535	Mg2 and Co2 transporter CorC
EHC68_RS13455	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EHC68_RS13460	COG2888	peptidyl-tyrosine sulfation
EHC68_RS13465	COG0495	leucyl-tRNA aminoacylation
EHC68_RS13470	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EHC68_RS13475	COG1466	dna polymerase III delta subunit
EHC68_RS13480	COG0799	negative regulation of ribosome biogenesis
EHC68_RS13485	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EHC68_RS13490	COG0768	penicillin binding
EHC68_RS13495	COG0772	Belongs to the SEDS family
EHC68_RS13500	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EHC68_RS13505	COG1686	Belongs to the peptidase S11 family
EHC68_RS13510	COG2921	Belongs to the UPF0250 family
EHC68_RS13515	COG0321	lipoyl(octanoyl) transferase activity
EHC68_RS13520	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EHC68_RS13525	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHC68_RS13530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHC68_RS13545	COG0366	Alpha amylase catalytic
EHC68_RS13550	COG1263	PTS System
EHC68_RS13550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC68_RS13560	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EHC68_RS13570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EHC68_RS13575	COG2011	ABC-type metal ion transport system permease component
EHC68_RS13580	COG1464	Belongs to the NlpA lipoprotein family
EHC68_RS13585	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
EHC68_RS13595	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHC68_RS13595	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHC68_RS13605	COG3706	GGDEF domain
EHC68_RS13605	COG0745	RESPONSE REGULATOR receiver
EHC68_RS13610	COG1611	Belongs to the LOG family
EHC68_RS13615	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC68_RS13625	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EHC68_RS13630	COG2363	Small membrane protein
EHC68_RS13640	COG0583	DNA-binding transcription factor activity
EHC68_RS13645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC68_RS13645	COG0301	tRNA thio-modification
EHC68_RS13650	COG2885	chlorophyll binding
EHC68_RS13655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EHC68_RS13660	COG1722	exodeoxyribonuclease VII activity
EHC68_RS13665	COG0142	geranyltranstransferase activity
EHC68_RS13670	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EHC68_RS13675	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EHC68_RS13680	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EHC68_RS13685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHC68_RS13705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC68_RS13705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC68_RS13710	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EHC68_RS13715	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EHC68_RS13720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHC68_RS13735	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EHC68_RS13740	COG2252	PERMEase
EHC68_RS13745	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC68_RS13770	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHC68_RS13770	COG0047	phosphoribosylformylglycinamidine synthase activity
EHC68_RS13775	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EHC68_RS13785	COG0590	tRNA wobble adenosine to inosine editing
EHC68_RS13790	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EHC68_RS13830	COG0484	heat shock protein binding
EHC68_RS13835	COG0443	Heat shock 70 kDa protein
EHC68_RS13845	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EHC68_RS13850	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHC68_RS13860	COG0497	DNA recombination
EHC68_RS13865	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC68_RS13870	COG2914	Belongs to the UPF0125 (RnfH) family
EHC68_RS13875	COG2867	negative regulation of translational initiation
EHC68_RS13880	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EHC68_RS13890	COG0582	viral genome integration into host DNA
EHC68_RS13895	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EHC68_RS13905	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EHC68_RS13920	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EHC68_RS13940	COG0328	RNA-DNA hybrid ribonuclease activity
EHC68_RS13945	COG2003	Belongs to the UPF0758 family
EHC68_RS13990	COG0328	RNA-DNA hybrid ribonuclease activity
EHC68_RS14035	COG3153	acetyltransferase
EHC68_RS14035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHC68_RS14055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EHC68_RS14060	COG2873	o-acetylhomoserine
EHC68_RS14095	COG1115	amino acid carrier protein
EHC68_RS14105	COG1584	GPR1 FUN34 yaaH family protein
EHC68_RS14120	COG0519	Catalyzes the synthesis of GMP from XMP
EHC68_RS14120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EHC68_RS14125	COG0517	IMP dehydrogenase activity
EHC68_RS14125	COG0516	GMP reductase activity
EHC68_RS14130	COG1570	exodeoxyribonuclease VII activity
EHC68_RS14145	COG1160	GTP binding
EHC68_RS14150	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC68_RS14155	COG2976	Protein conserved in bacteria
EHC68_RS14160	COG0124	histidyl-tRNA synthetase
EHC68_RS14165	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EHC68_RS14180	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EHC68_RS14185	COG0105	UTP biosynthetic process
EHC68_RS14190	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHC68_RS14195	COG2975	iron-sulfur cluster assembly
EHC68_RS14200	COG0633	Ferredoxin
EHC68_RS14205	COG0443	Heat shock 70 kDa protein
EHC68_RS14210	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EHC68_RS14220	COG0822	iron-sulfur transferase activity
EHC68_RS14225	COG1104	cysteine desulfurase activity
EHC68_RS14240	COG0483	inositol monophosphate 1-phosphatase activity
EHC68_RS14250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC68_RS14255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC68_RS14260	COG1862	Preprotein translocase
EHC68_RS14265	COG0343	queuine tRNA-ribosyltransferase activity
EHC68_RS14270	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EHC68_RS14280	COG0517	IMP dehydrogenase activity
EHC68_RS14290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EHC68_RS14300	COG0583	DNA-binding transcription factor activity
EHC68_RS14305	COG0450	alkyl hydroperoxide reductase
EHC68_RS14310	COG3142	Participates in the control of copper homeostasis
EHC68_RS14320	COG0704	Plays a role in the regulation of phosphate uptake
EHC68_RS14325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EHC68_RS14330	COG0581	inorganic phosphate transmembrane transporter activity
EHC68_RS14340	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EHC68_RS14345	COG0248	Ppx GppA phosphatase
EHC68_RS14355	COG5002	protein histidine kinase activity
EHC68_RS14360	COG0745	RESPONSE REGULATOR receiver
EHC68_RS14365	COG2974	May be involved in recombination
EHC68_RS14375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EHC68_RS14435	COG0542	response to heat
EHC68_RS14445	COG0564	pseudouridine synthase activity
EHC68_RS14450	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC68_RS14455	COG0741	lytic transglycosylase activity
EHC68_RS14460	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHC68_RS14465	COG1605	Chorismate mutase
EHC68_RS14465	COG0077	Prephenate dehydratase
EHC68_RS14470	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EHC68_RS14475	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EHC68_RS14485	COG0488	(ABC) transporter
EHC68_RS14500	COG0739	heme binding
EHC68_RS14505	COG0287	Prephenate dehydrogenase
EHC68_RS14505	COG1605	Chorismate mutase
EHC68_RS14510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC68_RS14515	COG1472	Belongs to the glycosyl hydrolase 3 family
EHC68_RS14520	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EHC68_RS14525	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHC68_RS14540	COG1966	Carbon starvation protein
EHC68_RS14545	COG3275	phosphorelay sensor kinase activity
EHC68_RS14550	COG3279	Response regulator of the LytR AlgR family
EHC68_RS14555	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EHC68_RS14560	COG1047	Peptidyl-prolyl cis-trans
EHC68_RS14565	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EHC68_RS14570	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHC68_RS14575	COG0196	riboflavin kinase activity
EHC68_RS14580	COG0728	peptidoglycan biosynthetic process
EHC68_RS14585	COG0268	Binds directly to 16S ribosomal RNA
EHC68_RS14595	COG0640	Transcriptional regulator
EHC68_RS14605	COG0583	DNA-binding transcription factor activity
EHC68_RS14610	COG1283	sodium-dependent phosphate transmembrane transporter activity
EHC68_RS14620	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EHC68_RS14625	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EHC68_RS14630	COG0730	response to heat
EHC68_RS14640	COG0494	nUDIX hydrolase
EHC68_RS14650	COG3066	DNA modification
EHC68_RS14660	COG0667	Aldo Keto reductase
EHC68_RS14675	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EHC68_RS14685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EHC68_RS14690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC68_RS14700	COG0716	FMN binding
EHC68_RS14710	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EHC68_RS14715	COG0513	Belongs to the DEAD box helicase family
EHC68_RS14720	COG3022	response to hydroperoxide
EHC68_RS14725	COG1115	amino acid carrier protein
EHC68_RS14740	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EHC68_RS14750	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EHC68_RS14755	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
EHC68_RS14760	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EHC68_RS14765	COG0083	homoserine kinase activity
EHC68_RS14780	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EHC68_RS14795	COG0745	RESPONSE REGULATOR receiver
EHC68_RS14805	COG5002	protein histidine kinase activity
EHC68_RS14805	COG0784	Response regulator, receiver
EHC68_RS14805	COG2198	Histidine kinase
EHC68_RS14810	COG5001	Diguanylate cyclase
EHC68_RS14810	COG3706	GGDEF domain
EHC68_RS14810	COG2203	Gaf domain
EHC68_RS14810	COG4251	negative regulation of phosphorylation
EHC68_RS14815	COG1242	4 iron, 4 sulfur cluster binding
EHC68_RS14820	COG0067	glutamate synthase
EHC68_RS14820	COG0069	glutamate synthase activity
EHC68_RS14820	COG0070	glutamate synthase
EHC68_RS14830	COG0069	glutamate synthase activity
EHC68_RS14830	COG0070	glutamate synthase
EHC68_RS14830	COG0067	glutamate synthase
EHC68_RS14835	COG0493	'glutamate synthase
EHC68_RS14845	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHC68_RS14855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHC68_RS14860	COG2860	membrane
EHC68_RS14865	COG0583	DNA-binding transcription factor activity
EHC68_RS14870	COG0730	response to heat
EHC68_RS14880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EHC68_RS14885	COG0505	Belongs to the CarA family
EHC68_RS14890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EHC68_RS14895	COG0494	nUDIX hydrolase
EHC68_RS14900	COG0653	protein targeting
EHC68_RS14910	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EHC68_RS14915	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EHC68_RS14920	COG0849	cell division
EHC68_RS14925	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EHC68_RS14930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EHC68_RS14935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHC68_RS14940	COG0772	Belongs to the SEDS family
EHC68_RS14945	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EHC68_RS14950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EHC68_RS14955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EHC68_RS14960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EHC68_RS14965	COG0768	penicillin binding
EHC68_RS14970	COG3116	cell division
EHC68_RS14975	COG0275	rRNA processing
EHC68_RS14990	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EHC68_RS15000	COG0792	nuclease activity
EHC68_RS15005	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EHC68_RS15010	COG2823	Periplasmic or secreted lipoprotein
EHC68_RS15015	COG2969	positive regulation of protein catabolic process
EHC68_RS15020	COG0625	glutathione transferase activity
EHC68_RS15025	COG2857	Cytochrome c1
EHC68_RS15030	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EHC68_RS15035	COG0723	plastoquinol--plastocyanin reductase activity
EHC68_RS15040	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EHC68_RS15045	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EHC68_RS15055	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EHC68_RS15065	COG3105	Protein conserved in bacteria
EHC68_RS15075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHC68_RS15080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHC68_RS15085	COG0187	DNA topoisomerase II activity
EHC68_RS15090	COG3150	esterase
EHC68_RS15100	COG3151	Protein conserved in bacteria
EHC68_RS15105	COG0494	nUDIX hydrolase
EHC68_RS15110	COG1538	Outer membrane efflux protein
EHC68_RS15115	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EHC68_RS15115	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EHC68_RS15120	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EHC68_RS15135	COG3025	triphosphatase activity
EHC68_RS15140	COG1392	Phosphate transport regulator
EHC68_RS15145	COG0306	phosphate transporter
EHC68_RS15150	COG4991	sh3 domain protein
EHC68_RS15160	COG3409	Peptidoglycan-binding domain 1 protein
EHC68_RS15160	COG3267	Type II secretory pathway component ExeA
EHC68_RS15165	COG0617	tRNA 3'-terminal CCA addition
EHC68_RS15170	COG1968	undecaprenyl-diphosphatase activity
EHC68_RS15175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHC68_RS15180	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EHC68_RS15190	COG0596	Alpha beta hydrolase
EHC68_RS15195	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EHC68_RS15200	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EHC68_RS15205	COG1610	YqeY-like protein
EHC68_RS15210	COG0358	DNA primase activity
EHC68_RS15215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHC68_RS15260	COG3550	peptidyl-serine autophosphorylation
EHC68_RS15280	COG1464	Belongs to the NlpA lipoprotein family
EHC68_RS15315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_RS15315	COG2213	PTS system mannitol-specific
EHC68_RS15320	COG0246	Mannitol dehydrogenase
EHC68_RS15325	COG3722	fumarate hydratase activity
EHC68_RS15335	COG5002	protein histidine kinase activity
EHC68_RS15350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EHC68_RS15355	COG1349	DNA-binding transcription factor activity
EHC68_RS15365	COG0469	pyruvate kinase activity
EHC68_RS15375	COG3706	GGDEF domain
EHC68_RS15380	COG0440	acetolactate synthase activity
EHC68_RS15385	COG0028	Belongs to the TPP enzyme family
EHC68_RS15390	COG1022	Amp-dependent synthetase and ligase
EHC68_RS15395	COG0583	DNA-binding transcription factor activity
EHC68_RS15415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHC68_RS15420	COG0473	3-isopropylmalate dehydrogenase activity
EHC68_RS15425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHC68_RS15430	COG0066	3-isopropylmalate dehydratase activity
EHC68_RS15440	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EHC68_RS15445	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EHC68_RS15450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC68_RS15455	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EHC68_RS15460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EHC68_RS15465	COG2967	ApaG domain
EHC68_RS15470	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EHC68_RS15485	COG2966	Psort location CytoplasmicMembrane, score
EHC68_RS15490	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EHC68_RS15500	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EHC68_RS15505	COG0142	geranyltranstransferase activity
EHC68_RS15515	COG0039	L-malate dehydrogenase activity
EHC68_RS15550	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EHC68_RS15555	COG1178	ABC-type Fe3 transport system permease component
EHC68_RS15560	COG4143	(ABC) transporter
EHC68_RS15565	COG0163	prenyltransferase activity
EHC68_RS15570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EHC68_RS15580	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EHC68_RS15585	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EHC68_RS15595	COG2105	PFAM AIG2 family protein
EHC68_RS15600	COG2911	Protein conserved in bacteria
EHC68_RS15605	COG0729	surface antigen
EHC68_RS15610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC68_RS15620	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EHC68_RS15635	COG4181	ATPase activity
EHC68_RS15655	COG0529	Catalyzes the synthesis of activated sulfate
EHC68_RS15660	COG0471	metal ion transport
EHC68_RS15660	COG3273	potassium ion transport
EHC68_RS15670	COG2895	sulfate adenylyltransferase (ATP) activity
EHC68_RS15675	COG0175	sulfate reduction
EHC68_RS15680	COG1648	precorrin-2 dehydrogenase activity
EHC68_RS15680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EHC68_RS15685	COG0737	Belongs to the 5'-nucleotidase family
EHC68_RS15695	COG0513	Belongs to the DEAD box helicase family
EHC68_RS15700	COG2153	protein acetylation
EHC68_RS15710	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC68_RS15720	COG0203	ribosomal protein L17
EHC68_RS15725	COG0202	RNA polymerase activity
EHC68_RS15735	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EHC68_RS15740	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EHC68_RS15750	COG0201	protein transport
EHC68_RS15755	COG0200	Binds to the 23S rRNA
EHC68_RS15760	COG1841	ribosomal large subunit assembly
EHC68_RS15775	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EHC68_RS15780	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EHC68_RS15785	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHC68_RS15790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EHC68_RS15795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EHC68_RS15800	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EHC68_RS15805	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EHC68_RS15810	COG0255	Belongs to the universal ribosomal protein uL29 family
EHC68_RS15820	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EHC68_RS15825	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EHC68_RS15830	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EHC68_RS15835	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EHC68_RS15845	COG0088	Forms part of the polypeptide exit tunnel
EHC68_RS15850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EHC68_RS15860	COG0254	rRNA binding
EHC68_RS15870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHC68_RS15875	COG1609	Transcriptional regulator
EHC68_RS15885	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EHC68_RS15890	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EHC68_RS15905	COG2003	Belongs to the UPF0758 family
EHC68_RS15935	COG1575	Belongs to the MenA family. Type 1 subfamily
EHC68_RS15940	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EHC68_RS15945	COG3074	FtsZ-dependent cytokinesis
EHC68_RS15955	COG1494	fructose-1,6-bisphosphatase
EHC68_RS15980	COG0149	triose-phosphate isomerase activity
EHC68_RS15985	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EHC68_RS16005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EHC68_RS16025	COG0438	transferase activity, transferring glycosyl groups
EHC68_RS16045	COG1215	transferase activity, transferring glycosyl groups
EHC68_RS16050	COG0110	maltose O-acetyltransferase activity
EHC68_RS16060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EHC68_RS16110	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC68_RS16120	COG1560	Kdo2-lipid A biosynthetic process
EHC68_RS16125	COG0859	PFAM glycosyl transferase family 9
EHC68_RS16130	COG1519	Transferase
EHC68_RS16140	COG0297	glycogen (starch) synthase activity
EHC68_RS16140	COG0438	transferase activity, transferring glycosyl groups
EHC68_RS16160	COG2030	dehydratase
EHC68_RS16165	COG0110	maltose O-acetyltransferase activity
EHC68_RS16185	COG3642	lipopolysaccharide core region biosynthetic process
EHC68_RS16190	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EHC68_RS16195	COG0859	PFAM glycosyl transferase family 9
EHC68_RS16200	COG0463	Glycosyl transferase, family 2
EHC68_RS16215	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EHC68_RS16220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EHC68_RS16235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EHC68_RS16240	COG2003	Belongs to the UPF0758 family
EHC68_RS16255	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EHC68_RS16260	COG1309	transcriptional regulator
EHC68_RS16265	COG1560	Kdo2-lipid A biosynthetic process
EHC68_RS16270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EHC68_RS16275	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EHC68_RS16280	COG1561	YicC-like family, N-terminal region
EHC68_RS16290	COG4608	Belongs to the ABC transporter superfamily
EHC68_RS16295	COG0444	Belongs to the ABC transporter superfamily
EHC68_RS16300	COG0747	negative chemotaxis
EHC68_RS16310	COG4174	ABC transporter (Permease)
EHC68_RS16335	COG0811	peptide transport
EHC68_RS16340	COG0848	biopolymer transport protein
EHC68_RS16355	COG0194	GDP metabolic process
EHC68_RS16360	COG1758	RNA polymerase activity
EHC68_RS16365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHC68_RS16370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC68_RS16375	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EHC68_RS16380	COG2233	PERMEase
EHC68_RS16385	COG2205	protein histidine kinase activity
EHC68_RS16390	COG0745	RESPONSE REGULATOR receiver
EHC68_RS16400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC68_RS16410	COG2183	response to ionizing radiation
EHC68_RS16420	COG0596	Alpha beta hydrolase
EHC68_RS16425	COG1040	competence protein
EHC68_RS16430	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EHC68_RS16430	COG0316	Belongs to the HesB IscA family
EHC68_RS16435	COG0494	nUDIX hydrolase
EHC68_RS16440	COG1218	3'(2'),5'-bisphosphate nucleotidase
EHC68_RS16450	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EHC68_RS16455	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EHC68_RS16460	COG3156	type II secretion system protein K
EHC68_RS16465	COG4795	General secretion pathway protein
EHC68_RS16470	COG2165	general secretion pathway protein
EHC68_RS16475	COG2165	general secretion pathway protein
EHC68_RS16480	COG2165	general secretion pathway protein
EHC68_RS16485	COG1459	type II secretion system
EHC68_RS16490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC68_RS16500	COG3031	protein transport across the cell outer membrane
EHC68_RS16505	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EHC68_RS16510	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EHC68_RS16515	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EHC68_RS16525	COG0456	acetyltransferase
EHC68_RS16530	COG1490	D-aminoacyl-tRNA deacylase activity
EHC68_RS16535	COG1295	ribonuclease BN
EHC68_RS16555	COG0174	glutamine synthetase
EHC68_RS16565	COG3852	Histidine kinase
EHC68_RS16570	COG2204	response regulator
EHC68_RS16580	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHC68_RS16585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHC68_RS16620	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EHC68_RS16630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC68_RS16630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC68_RS16655	COG0084	hydrolase, TatD family'
EHC68_RS16665	COG0805	protein transport
EHC68_RS16675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHC68_RS16680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EHC68_RS16685	COG3165	ubiquinone biosynthetic process from chorismate
EHC68_RS16690	COG2226	methyltransferase
EHC68_RS16695	COG1322	Protein conserved in bacteria
EHC68_RS16710	COG0628	permease
EHC68_RS16760	COG2823	Periplasmic or secreted lipoprotein
EHC68_RS16770	COG2081	HI0933 family
EHC68_RS16780	COG1528	Iron-storage protein
EHC68_RS16785	COG0589	response to stress
EHC68_RS16790	COG0697	spore germination
EHC68_RS16800	COG0742	ribosomal rna small subunit methyltransferase
EHC68_RS16805	COG5001	Diguanylate cyclase
EHC68_RS16805	COG5002	protein histidine kinase activity
EHC68_RS16810	COG1522	sequence-specific DNA binding
EHC68_RS16815	COG0339	signal peptide processing
EHC68_RS16820	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EHC68_RS16825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC68_RS16830	COG0583	DNA-binding transcription factor activity
EHC68_RS16835	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EHC68_RS16840	COG0800	Aldolase
EHC68_RS16845	COG2610	gluconate transmembrane transporter activity
EHC68_RS16850	COG3265	gluconokinase activity
EHC68_RS16855	COG0129	dihydroxy-acid dehydratase activity
EHC68_RS16860	COG2076	Multidrug Resistance protein
EHC68_RS16870	COG0583	DNA-binding transcription factor activity
EHC68_RS16875	COG1609	Transcriptional regulator
EHC68_RS16915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC68_RS16925	COG0747	negative chemotaxis
EHC68_RS16930	COG4172	Belongs to the ABC transporter superfamily
EHC68_RS16995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_RS17000	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC68_RS17010	COG2960	long-chain fatty acid transporting porin activity
EHC68_RS17015	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EHC68_RS17020	COG0583	DNA-binding transcription factor activity
EHC68_RS17060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EHC68_RS17070	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHC68_RS17075	COG0408	coproporphyrinogen oxidase activity
EHC68_RS17080	COG0009	L-threonylcarbamoyladenylate synthase
EHC68_RS17085	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EHC68_RS17090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EHC68_RS17095	COG0551	DNA topoisomerase type I activity
EHC68_RS17100	COG2922	Belongs to the Smg family
EHC68_RS17115	COG0242	peptide deformylase activity
EHC68_RS17120	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EHC68_RS17125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHC68_RS17125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHC68_RS17130	COG0569	domain protein
EHC68_RS17135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC68_RS17145	COG1272	protein, Hemolysin III
EHC68_RS17150	COG4326	sporulation control protein
EHC68_RS17160	COG3084	Protein conserved in bacteria
EHC68_RS17170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EHC68_RS17175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC68_RS17180	COG0204	Acyl-transferase
EHC68_RS17190	COG0606	chelatase, subunit chli
EHC68_RS17200	COG3978	acetolactate synthase activity
EHC68_RS17205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EHC68_RS17210	COG0129	dihydroxy-acid dehydratase activity
EHC68_RS17220	COG0583	DNA-binding transcription factor activity
EHC68_RS17225	COG2814	Major facilitator Superfamily
EHC68_RS17230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_RS17235	COG0765	amino acid transport
EHC68_RS17240	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EHC68_RS17245	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EHC68_RS17250	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EHC68_RS17255	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EHC68_RS17260	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EHC68_RS17265	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHC68_RS17280	COG0356	it plays a direct role in the translocation of protons across the membrane
EHC68_RS17285	COG3312	ion transport
EHC68_RS17290	COG1475	DNA binding
EHC68_RS17295	COG1192	Involved in chromosome partitioning
EHC68_RS17300	COG0357	Ribosomal RNA small subunit methyltransferase G
EHC68_RS17305	COG0445	tRNA wobble uridine modification
EHC68_RS17325	COG1395	domain, Protein
EHC68_RS17350	COG0482	sulfurtransferase activity
EHC68_RS17365	COG1104	cysteine desulfurase activity
EHC68_RS17400	COG4974	Belongs to the 'phage' integrase family
EHC68_RS17405	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EHC68_RS17410	COG0706	membrane insertase activity
EHC68_RS17415	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EHC68_RS17420	COG0594	ribonuclease P activity
EHC68_RS17430	COG1126	abc transporter atp-binding protein
EHC68_RS17495	COG3547	Transposase (IS116 IS110 IS902 family)
EHC68_RS17525	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EHC68_RS17590	COG3547	Transposase (IS116 IS110 IS902 family)
EHC68_RS17635	COG1349	DNA-binding transcription factor activity
EHC68_RS17640	COG0738	Major facilitator superfamily
EHC68_RS17655	COG4154	Belongs to the RbsD FucU family
EHC68_RS17660	COG0235	Class ii aldolase
EHC68_RS17675	COG2003	Belongs to the UPF0758 family
EHC68_RS17710	COG0641	radical SAM
EHC68_RS17725	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EHC68_RS17755	COG3069	C4-dicarboxylate transmembrane transporter activity
EHC68_RS17760	COG1704	LemA family
EHC68_RS17765	COG0501	Belongs to the peptidase M48B family
EHC68_RS17795	COG0641	radical SAM
EHC68_RS17815	COG3111	PFAM Bacterial OB fold (BOF) protein
EHC68_RS17820	COG1597	lipid kinase activity
EHC68_RS17825	COG0583	DNA-binding transcription factor activity
EHC68_RS17830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC68_RS17860	COG0714	Associated with various cellular activities
EHC68_RS17865	COG0641	radical SAM
EHC68_RS17870	COG3119	arylsulfatase activity
EHC68_RS17885	COG3119	arylsulfatase activity
EHC68_RS17890	COG3119	arylsulfatase activity
EHC68_RS17895	COG0745	RESPONSE REGULATOR receiver
EHC68_RS17910	COG2205	protein histidine kinase activity
EHC68_RS17910	COG0784	Response regulator, receiver
EHC68_RS17910	COG2198	Histidine kinase
EHC68_RS17915	COG1879	ABC-type sugar transport system periplasmic component
EHC68_RS17920	COG1803	Methylglyoxal synthase
EHC68_RS17925	COG0210	DNA helicase
EHC68_RS17930	COG1289	transmembrane transporter activity
EHC68_RS17965	COG1629	transport
EHC68_RS17965	COG4771	TonB-dependent receptor
EHC68_RS17980	COG0789	Transcriptional regulator
EHC68_RS17985	COG4604	ABC transporter, ATP-binding protein
EHC68_RS17990	COG4605	iron ion homeostasis
EHC68_RS17995	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC68_RS18000	COG4607	ABC-type enterochelin transport system periplasmic component
EHC68_RS18030	COG0443	Heat shock 70 kDa protein
EHC68_RS18065	COG0625	glutathione transferase activity
EHC68_RS18080	COG4160	amino acid transport
EHC68_RS18085	COG4215	(ABC) transporter
EHC68_RS18090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_RS18095	COG1126	abc transporter atp-binding protein
EHC68_RS18140	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_RS18160	COG1902	pentaerythritol trinitrate reductase activity
EHC68_RS18165	COG0109	protoheme IX farnesyltransferase activity
EHC68_RS18170	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EHC68_RS18175	COG1845	cytochrome c oxidase, subunit III
EHC68_RS18180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHC68_RS18185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EHC68_RS18190	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_RS18200	COG1024	Enoyl-CoA hydratase
EHC68_RS18205	COG1024	Enoyl-CoA hydratase
EHC68_RS18220	COG0183	Belongs to the thiolase family
EHC68_RS18230	COG1960	acyl-CoA dehydrogenase activity
EHC68_RS18235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EHC68_RS18240	COG1024	Enoyl-CoA hydratase
EHC68_RS18250	COG5413	integral membrane protein
EHC68_RS18265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHC68_RS18275	COG5001	Diguanylate cyclase
EHC68_RS18280	COG0513	Belongs to the DEAD box helicase family
EHC68_RS18285	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EHC68_RS18300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EHC68_RS18320	COG0641	radical SAM
EHC68_RS18355	COG0840	transmembrane signaling receptor activity
EHC68_RS18360	COG1119	ATPase activity
EHC68_RS18365	COG2200	EAL domain
EHC68_RS18385	COG0513	Belongs to the DEAD box helicase family
EHC68_RS18390	COG0523	cobalamin synthesis protein
EHC68_RS18400	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EHC68_RS18410	COG0133	tryptophan synthase activity
EHC68_RS18415	COG4628	conserved protein (DUF2132)
EHC68_RS18420	COG0513	Belongs to the DEAD box helicase family
EHC68_RS18425	COG3530	Putative quorum-sensing-regulated virulence factor
EHC68_RS18450	COG2154	pterin-4-alpha-carbinolamine dehydratase
EHC68_RS18455	COG3186	Phenylalanine-4-hydroxylase
EHC68_RS18460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC68_RS18465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC68_RS18505	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EHC68_RS18515	COG2133	pyrroloquinoline quinone binding
EHC68_RS18525	COG0783	Belongs to the Dps family
EHC68_RS18530	COG0840	transmembrane signaling receptor activity
EHC68_RS18540	COG0577	efflux transmembrane transporter activity
EHC68_RS18540	COG1136	(ABC) transporter
EHC68_RS18560	COG2199	diguanylate cyclase activity
EHC68_RS18575	COG3036	rescue of stalled ribosome
EHC68_RS18580	COG1278	Cold shock
EHC68_RS18615	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC68_RS18620	COG0109	protoheme IX farnesyltransferase activity
EHC68_RS18625	COG1612	heme a metabolic process
EHC68_RS18650	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EHC68_RS18660	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EHC68_RS18665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC68_RS18675	COG1280	lysine exporter protein (LysE YggA)
EHC68_RS18680	COG2207	Transcriptional regulator
EHC68_RS18710	COG0697	spore germination
EHC68_RS18735	COG2814	Major facilitator Superfamily
EHC68_RS18740	COG0583	DNA-binding transcription factor activity
EHC68_RS18745	COG5001	Diguanylate cyclase
EHC68_RS18750	COG0739	heme binding
EHC68_RS18810	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHC68_RS18815	COG1072	(Pantothenic acid kinase))
EHC68_RS18825	COG1063	alcohol dehydrogenase
EHC68_RS18830	COG2213	PTS system mannitol-specific
EHC68_RS18835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_RS18855	COG0798	PFAM Bile acid sodium symporter
EHC68_RS18865	COG1881	PFAM PEBP family protein
EHC68_RS18875	COG2706	6-phosphogluconolactonase activity
EHC68_RS18880	COG0840	transmembrane signaling receptor activity
EHC68_RS18890	COG1131	(ABC) transporter
EHC68_RS18895	COG0842	Transport permease protein
EHC68_RS18910	COG3383	formate dehydrogenase (NAD+) activity
EHC68_RS18955	COG2199	diguanylate cyclase activity
EHC68_RS18955	COG2203	Gaf domain
EHC68_RS18965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC68_RS18975	COG2067	long-chain fatty acid transport protein
EHC68_RS18985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_RS18995	COG1505	serine-type exopeptidase activity
EHC68_RS19000	COG0488	(ABC) transporter
EHC68_RS19005	COG0589	response to stress
EHC68_RS19010	COG2249	NAD(P)H dehydrogenase (quinone) activity
EHC68_RS19030	COG0366	Alpha amylase catalytic
EHC68_RS19040	COG4934	collagen metabolic process
EHC68_RS19055	COG0583	DNA-binding transcription factor activity
EHC68_RS19065	COG0783	Belongs to the Dps family
EHC68_RS19070	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EHC68_RS19095	COG0494	nUDIX hydrolase
EHC68_RS19105	COG3458	cephalosporin-C deacetylase activity
EHC68_RS19125	COG2814	Major facilitator Superfamily
EHC68_RS19140	COG0328	RNA-DNA hybrid ribonuclease activity
EHC68_RS19170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EHC68_RS19175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC68_RS19185	COG0784	Response regulator, receiver
EHC68_RS19185	COG0835	chemotaxis
EHC68_RS19195	COG0748	coenzyme F420 binding
EHC68_RS19200	COG3721	Heme iron utilization protein
EHC68_RS19210	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EHC68_RS19215	COG0811	peptide transport
EHC68_RS19220	COG0848	biopolymer transport protein
EHC68_RS19230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC68_RS19235	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EHC68_RS19275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EHC68_RS19280	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EHC68_RS19285	COG0633	Ferredoxin
EHC68_RS19285	COG3217	Mosc domain protein beta barrel domain protein
EHC68_RS19285	COG0633	Ferredoxin
EHC68_RS19285	COG3217	Mosc domain protein beta barrel domain protein
EHC68_RS19295	COG0401	homolog of Blt101
EHC68_RS19305	COG0418	dihydroorotase activity
EHC68_RS19310	COG2354	Protein conserved in bacteria
EHC68_RS19340	COG2207	Transcriptional regulator
EHC68_RS19340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHC68_RS19345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC68_RS19390	COG0513	Belongs to the DEAD box helicase family
EHC68_RS19400	COG0583	DNA-binding transcription factor activity
EHC68_RS19415	COG1902	pentaerythritol trinitrate reductase activity
EHC68_RS19420	COG1063	alcohol dehydrogenase
EHC68_RS19430	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_RS19445	COG3122	Protein conserved in bacteria
EHC68_RS19475	COG0583	DNA-binding transcription factor activity
EHC68_RS19485	COG0252	asparaginase activity
EHC68_RS19490	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EHC68_RS19495	COG0574	Belongs to the PEP-utilizing enzyme family
EHC68_RS19495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHC68_RS19515	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHC68_RS19520	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC68_RS19535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_RS19555	COG3706	GGDEF domain
EHC68_RS19575	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC68_RS19605	COG3842	ATPase activity
EHC68_RS19640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHC68_RS19690	COG0583	DNA-binding transcription factor activity
EHC68_RS19700	COG4948	Mandelate Racemase Muconate Lactonizing
EHC68_RS19710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC68_RS19735	COG1342	Belongs to the UPF0251 family
EHC68_RS19745	COG3015	lipoprotein NlpE involved in copper resistance
EHC68_RS19755	COG3713	MltA-interacting MipA family protein
EHC68_RS19770	COG0583	DNA-binding transcription factor activity
EHC68_RS19800	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EHC68_RS19810	COG1335	isochorismatase
EHC68_RS19820	COG0753	catalase activity
EHC68_RS19830	COG1349	DNA-binding transcription factor activity
EHC68_RS19835	COG0346	lactoylglutathione lyase activity
EHC68_RS19850	COG0583	DNA-binding transcription factor activity
EHC68_RS19860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC68_RS19865	COG2070	2-Nitropropane dioxygenase
EHC68_RS19870	COG0737	Belongs to the 5'-nucleotidase family
EHC68_RS19880	COG1309	transcriptional regulator
EHC68_RS19900	COG1280	lysine exporter protein (LysE YggA)
EHC68_RS19910	COG0459	protein refolding
EHC68_RS19915	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHC68_RS19920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC68_RS19950	COG1304	FMN binding
EHC68_RS19970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_RS19975	COG1256	bacterial-type flagellum assembly
EHC68_RS19975	COG4786	Flagellar basal body rod
EHC68_RS19985	COG1706	bacterial-type flagellum-dependent cell motility
EHC68_RS19990	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EHC68_RS19995	COG4786	Flagellar basal body rod
EHC68_RS20000	COG4787	bacterial-type flagellum-dependent cell motility
EHC68_RS20005	COG1749	Flagellar hook protein flgE
EHC68_RS20010	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EHC68_RS20015	COG1558	bacterial-type flagellum-dependent cell motility
EHC68_RS20020	COG1815	bacterial-type flagellum-dependent cell motility
EHC68_RS20040	COG0741	lytic transglycosylase activity
EHC68_RS20045	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHC68_RS20065	COG1760	l-serine dehydratase
EHC68_RS20090	COG0583	DNA-binding transcription factor activity
EHC68_RS20105	COG2866	Carboxypeptidase
EHC68_RS20110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC68_RS20120	COG2990	Protein conserved in bacteria
EHC68_RS20145	COG3842	ATPase activity
EHC68_RS20155	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC68_RS20170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC68_RS20175	COG1609	Transcriptional regulator
EHC68_RS20205	COG3240	lipase activity
EHC68_RS20220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_RS20225	COG2067	long-chain fatty acid transport protein
EHC68_RS20235	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EHC68_RS20250	COG1011	Hydrolase
EHC68_RS20290	COG0110	maltose O-acetyltransferase activity
EHC68_RS20295	COG1765	OsmC-like protein
EHC68_RS20300	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC68_RS20300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC68_RS20315	COG3046	protein related to deoxyribodipyrimidine photolyase
EHC68_RS20320	COG0415	Belongs to the DNA photolyase family
EHC68_RS20325	COG3706	GGDEF domain
EHC68_RS20340	COG0840	transmembrane signaling receptor activity
EHC68_RS20345	COG3706	GGDEF domain
EHC68_RS20350	COG3145	DNA-N1-methyladenine dioxygenase activity
EHC68_RS20360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC68_RS20380	COG3033	Beta-eliminating lyase
EHC68_RS20390	COG0579	oxidoreductase
EHC68_RS20420	COG3706	GGDEF domain
EHC68_RS20430	COG4191	Histidine kinase
EHC68_RS20465	COG0583	DNA-binding transcription factor activity
EHC68_RS20470	COG0189	ligase activity
EHC68_RS20475	COG4067	protein conserved in archaea
EHC68_RS20475	COG0189	ligase activity
EHC68_RS20485	COG1166	arginine decarboxylase activity
EHC68_RS20490	COG0010	Belongs to the arginase family
EHC68_RS20495	COG2814	Major facilitator Superfamily
EHC68_RS20500	COG1770	oligopeptidase
EHC68_RS20515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EHC68_RS20520	COG1121	(ABC) transporter
EHC68_RS20525	COG0803	Belongs to the bacterial solute-binding protein 9 family
EHC68_RS20565	COG0848	biopolymer transport protein
EHC68_RS20570	COG0811	peptide transport
EHC68_RS20575	COG0811	peptide transport
EHC68_RS20595	COG0745	RESPONSE REGULATOR receiver
EHC68_RS20605	COG0584	glycerophosphoryl diester phosphodiesterase
EHC68_RS20615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHC68_RS20675	COG1901	pseudouridine methyltransferase
EHC68_RS20680	COG0312	modulator of DNA gyrase
EHC68_RS20695	COG0351	phosphomethylpyrimidine kinase
EHC68_RS20700	COG1116	anion transmembrane transporter activity
EHC68_RS20705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHC68_RS20710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHC68_RS20715	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EHC68_RS20720	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EHC68_RS20725	COG0352	thiamine-phosphate diphosphorylase activity
EHC68_RS20735	COG0243	molybdopterin cofactor binding
EHC68_RS20740	COG3005	denitrification pathway
EHC68_RS20750	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_RS20765	COG0456	acetyltransferase
EHC68_RS20785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC68_RS20790	COG1929	Belongs to the glycerate kinase type-1 family
EHC68_RS20795	COG2610	gluconate transmembrane transporter activity
EHC68_RS20800	COG3835	regulator
EHC68_RS20840	COG0583	DNA-binding transcription factor activity
EHC68_RS20855	COG0641	radical SAM
EHC68_RS20860	COG0583	DNA-binding transcription factor activity
EHC68_RS20870	COG0583	DNA-binding transcription factor activity
EHC68_RS20880	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EHC68_RS20885	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EHC68_RS20885	COG3408	Glycogen debranching enzyme
EHC68_RS20915	COG3047	cAMP biosynthetic process
EHC68_RS20920	COG1357	PFAM Pentapeptide repeats (8 copies)
EHC68_RS20950	COG2375	cellular response to nickel ion
EHC68_RS20955	COG0823	Involved in the tonB-independent uptake of proteins
EHC68_RS20960	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC68_RS20980	COG0800	Aldolase
EHC68_RS20985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC68_RS21000	COG1917	Cupin 2, conserved barrel domain protein
EHC68_RS21010	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_RS21015	COG1414	Transcriptional regulator
EHC68_RS21030	COG0583	DNA-binding transcription factor activity
EHC68_RS21035	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EHC68_RS21040	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EHC68_RS21055	COG2199	diguanylate cyclase activity
EHC68_RS21065	COG0561	phosphatase activity
EHC68_RS21070	COG0583	DNA-binding transcription factor activity
EHC68_RS21085	COG0564	pseudouridine synthase activity
EHC68_RS21090	COG0534	Mate efflux family protein
EHC68_RS21100	COG5001	Diguanylate cyclase
EHC68_RS21110	COG3123	guanosine phosphorylase activity
EHC68_RS21150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHC68_RS21160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHC68_RS21165	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EHC68_RS21180	COG2259	Doxx family
EHC68_RS21185	COG1741	Belongs to the pirin family
EHC68_RS21205	COG0363	glucosamine-6-phosphate deaminase activity
EHC68_RS21220	COG0786	glutamate:sodium symporter activity
EHC68_RS21225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC68_RS21230	COG1131	(ABC) transporter
EHC68_RS21240	COG0786	glutamate:sodium symporter activity
EHC68_RS21275	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHC68_RS21285	COG3279	Response regulator of the LytR AlgR family
EHC68_RS21290	COG3275	phosphorelay sensor kinase activity
EHC68_RS21310	COG1136	(ABC) transporter
EHC68_RS21325	COG0772	Belongs to the SEDS family
EHC68_RS21330	COG0217	transcriptional regulatory protein
EHC68_RS21355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC68_RS21355	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
EHC68_RS21365	COG0444	Belongs to the ABC transporter superfamily
EHC68_RS21370	COG4608	Belongs to the ABC transporter superfamily
EHC68_RS21395	COG1444	tRNA N-acetyltransferase activity
EHC68_RS21415	COG3340	Belongs to the peptidase S51 family
EHC68_RS21420	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EHC68_RS21425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC68_RS21425	COG1263	PTS System
EHC68_RS21430	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHC68_RS21450	COG4166	transmembrane transport
EHC68_RS21505	COG0259	pyridoxamine-phosphate oxidase activity
EHC68_RS21535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC68_RS21580	COG1132	(ABC) transporter
EHC68_RS21590	COG2207	Transcriptional regulator
EHC68_RS21615	COG0800	Aldolase
EHC68_RS21620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC68_RS21625	COG1904	glucuronate isomerase
EHC68_RS21630	COG0246	Mannitol dehydrogenase
EHC68_RS21640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EHC68_RS21650	COG2186	Transcriptional regulator
EHC68_RS21655	COG1312	Catalyzes the dehydration of D-mannonate
EHC68_RS21660	COG0513	Belongs to the DEAD box helicase family
EHC68_RS21665	COG2258	MOSC domain
EHC68_RS21680	COG1486	melibiose metabolic process
EHC68_RS21685	COG0583	DNA-binding transcription factor activity
EHC68_RS21690	COG0840	transmembrane signaling receptor activity
EHC68_RS21705	COG1595	DNA-templated transcription, initiation
EHC68_RS21735	COG3634	alkyl hydroperoxide reductase activity
EHC68_RS21740	COG0450	alkyl hydroperoxide reductase
EHC68_RS21745	COG1846	Transcriptional regulator
EHC68_RS21750	COG1764	response to oxidative stress
EHC68_RS21775	COG2160	L-arabinose isomerase activity
EHC68_RS21785	COG1069	ribulokinase activity
EHC68_RS21790	COG1879	ABC-type sugar transport system periplasmic component
EHC68_RS21795	COG1129	ABC transporter
EHC68_RS21800	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHC68_RS21825	COG0745	RESPONSE REGULATOR receiver
EHC68_RS21835	COG1653	transport
EHC68_RS21840	COG0019	diaminopimelate decarboxylase activity
EHC68_RS21845	COG4264	IucA IucC family
EHC68_RS21870	COG4772	TonB-dependent receptor
EHC68_RS21875	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EHC68_RS21880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC68_RS21885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC68_RS21890	COG1120	ATPase activity
EHC68_RS21895	COG0840	transmembrane signaling receptor activity
EHC68_RS21900	COG0612	Peptidase, M16
EHC68_RS21910	COG0739	heme binding
EHC68_RS21935	COG4580	involved in the transport of maltose and maltodextrins
EHC68_RS21960	COG2356	endonuclease I
EHC68_RS21980	COG1982	Orn Lys Arg decarboxylase major
EHC68_RS21985	COG0531	amino acid
EHC68_RS21995	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EHC68_RS22005	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EHC68_RS22010	COG1162	GTPase activity
EHC68_RS22015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC68_RS22015	COG1263	PTS System
EHC68_RS22025	COG1999	signal sequence binding
EHC68_RS22040	COG2909	trisaccharide binding
EHC68_RS22055	COG0058	SHG alpha-glucan phosphorylase activity
EHC68_RS22060	COG1640	4-alpha-glucanotransferase
EHC68_RS22065	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EHC68_RS22070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EHC68_RS22075	COG0366	Alpha amylase catalytic
EHC68_RS22090	COG3366	ferrous iron transmembrane transporter activity
EHC68_RS22095	COG0700	Nucleoside recognition
EHC68_RS22100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC68_RS22105	COG3339	Conserved Protein
EHC68_RS22110	COG1301	dicarboxylic acid transport
EHC68_RS22120	COG0583	DNA-binding transcription factor activity
EHC68_RS22135	COG0489	protein tyrosine kinase activity
EHC68_RS22135	COG3206	protein involved in exopolysaccharide biosynthesis
EHC68_RS22155	COG2095	MarC family integral membrane protein
EHC68_RS22160	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC68_RS22165	COG3397	chitin binding
EHC68_RS22185	COG1686	Belongs to the peptidase S11 family
EHC68_RS22210	COG0583	DNA-binding transcription factor activity
EHC68_RS22215	COG4628	conserved protein (DUF2132)
EHC68_RS22225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC68_RS22235	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC68_RS22240	COG0628	permease
EHC68_RS22260	COG1538	Outer membrane efflux protein
EHC68_RS22285	COG2814	Major facilitator Superfamily
EHC68_RS22300	COG0454	-acetyltransferase
EHC68_RS22310	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHC68_RS22315	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC68_RS22350	COG1360	Flagellar Motor Protein
EHC68_RS22355	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EHC68_RS22360	COG1191	sigma factor activity
EHC68_RS22365	COG1580	Controls the rotational direction of flagella during chemotaxis
EHC68_RS22380	COG1516	flagellar protein fliS
EHC68_RS22395	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_RS22410	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHC68_RS22420	COG1987	bacterial-type flagellum assembly
EHC68_RS22445	COG2204	response regulator
EHC68_RS22460	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC68_RS22500	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHC68_RS22520	COG0346	lactoylglutathione lyase activity
EHC68_RS22555	COG0745	RESPONSE REGULATOR receiver
EHC68_RS22575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_RS22585	COG0156	8-amino-7-oxononanoate synthase activity
EHC68_RS22590	COG1063	alcohol dehydrogenase
EHC68_RS22630	COG0668	transmembrane transport
EHC68_RS22640	COG1304	FMN binding
EHC68_RS22645	COG1620	l-lactate permease
EHC68_RS22650	COG0583	DNA-binding transcription factor activity
EHC68_RS22655	COG1505	serine-type exopeptidase activity
EHC68_RS22660	COG4172	Belongs to the ABC transporter superfamily
EHC68_RS22670	COG1067	ATP-dependent peptidase activity
EHC68_RS22700	COG1247	-acetyltransferase
EHC68_RS22705	COG0437	4 iron, 4 sulfur cluster binding
EHC68_RS22710	COG0348	domain, Protein
EHC68_RS22725	COG1122	ATPase activity
EHC68_RS22730	COG4720	Psort location CytoplasmicMembrane, score
EHC68_RS22735	COG1566	PFAM secretion protein HlyD family protein
EHC68_RS22745	COG3706	GGDEF domain
EHC68_RS22760	COG0813	purine-nucleoside phosphorylase activity
EHC68_RS22770	COG3272	Protein of unknown function (DUF1722)
EHC68_RS22775	COG0789	Transcriptional regulator
EHC68_RS22780	COG0415	Belongs to the DNA photolyase family
EHC68_RS22785	COG1388	LysM domain
EHC68_RS22785	COG1376	ErfK ybiS ycfS ynhG family protein
EHC68_RS22795	COG0513	Belongs to the DEAD box helicase family
EHC68_RS22800	COG1770	oligopeptidase
EHC68_RS22805	COG4771	TonB-dependent receptor
EHC68_RS22830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EHC68_RS22835	COG0573	inorganic phosphate transmembrane transporter activity
EHC68_RS22840	COG0581	inorganic phosphate transmembrane transporter activity
EHC68_RS22845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EHC68_RS22860	COG2304	oxidoreductase activity
EHC68_RS22880	COG0714	Associated with various cellular activities
EHC68_RS22890	COG0840	transmembrane signaling receptor activity
EHC68_RS22900	COG2197	response regulator
EHC68_RS22950	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EHC68_RS22955	COG1120	ATPase activity
EHC68_RS22960	COG4774	siderophore transport
EHC68_RS22965	COG1132	(ABC) transporter
EHC68_RS22970	COG5002	protein histidine kinase activity
EHC68_RS22980	COG0569	domain protein
EHC68_RS22995	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EHC68_RS23000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC68_RS23015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC68_RS23015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC68_RS23015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_RS23020	COG2207	Transcriptional regulator
EHC68_RS23030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC68_RS23035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC68_RS23040	COG2084	Dehydrogenase
EHC68_RS23045	COG0753	catalase activity
EHC68_RS23055	COG2130	NADP-dependent
EHC68_RS23060	COG1309	transcriptional regulator
EHC68_RS23095	COG0438	transferase activity, transferring glycosyl groups
EHC68_RS23125	COG3842	ATPase activity
EHC68_RS23135	COG1175	transmembrane transport
EHC68_RS23140	COG3833	ABC-type maltose transport systems, permease component
EHC68_RS23160	COG3746	phosphate-selective porin O and P
EHC68_RS23180	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_RS23210	COG0625	glutathione transferase activity
EHC68_RS23220	COG1686	Belongs to the peptidase S11 family
EHC68_RS23240	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHC68_RS23255	COG1278	Cold shock
EHC68_RS23260	COG1741	Belongs to the pirin family
EHC68_RS23275	COG1846	Transcriptional regulator
EHC68_RS23290	COG2814	Major facilitator Superfamily
EHC68_RS23300	COG0673	inositol 2-dehydrogenase activity
EHC68_RS23305	COG2194	sulfuric ester hydrolase activity
EHC68_RS23310	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EHC68_RS23320	COG2205	protein histidine kinase activity
EHC68_RS23325	COG0745	RESPONSE REGULATOR receiver
EHC68_RS23330	COG4221	oxidoreductase activity
EHC68_RS23350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC68_RS23370	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC68_RS23380	COG2814	Major facilitator Superfamily
EHC68_RS23395	COG1418	mRNA catabolic process
EHC68_RS23405	COG0402	S-adenosylhomocysteine deaminase activity
EHC68_RS23410	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EHC68_RS23420	COG2239	Acts as a magnesium transporter
EHC68_RS23425	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EHC68_RS23440	COG0531	amino acid
EHC68_RS23450	COG1522	sequence-specific DNA binding
EHC68_RS23480	COG0673	inositol 2-dehydrogenase activity
EHC68_RS23485	COG0534	Mate efflux family protein
EHC68_RS23490	COG2926	Belongs to the UPF0265 family
EHC68_RS23505	COG3132	Protein of unknown function, DUF480
EHC68_RS23510	COG2827	Endonuclease containing a URI domain
EHC68_RS23515	COG1879	ABC-type sugar transport system periplasmic component
EHC68_RS23520	COG0784	Response regulator, receiver
EHC68_RS23520	COG2205	protein histidine kinase activity
EHC68_RS23530	COG1566	PFAM secretion protein HlyD family protein
EHC68_RS23550	COG1522	sequence-specific DNA binding
EHC68_RS23575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC68_RS23580	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC68_RS23600	COG0183	Belongs to the thiolase family
EHC68_RS23620	COG3005	denitrification pathway
EHC68_RS23630	COG0243	molybdopterin cofactor binding
EHC68_RS23640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EHC68_RS23645	COG3850	Histidine kinase
EHC68_RS23650	COG2197	response regulator
EHC68_RS23665	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC68_RS23685	COG0840	transmembrane signaling receptor activity
EHC68_RS23695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC68_RS23705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC68_RS23710	COG2814	Major facilitator Superfamily
EHC68_RS23720	COG0840	transmembrane signaling receptor activity
EHC68_RS23725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHC68_RS23730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHC68_RS23755	COG2897	thiosulfate sulfurtransferase activity
EHC68_RS23775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EHC68_RS23785	COG0302	gtp cyclohydrolase
EHC68_RS23790	COG1914	H( )-stimulated, divalent metal cation uptake system
EHC68_RS23800	COG0038	chloride channel
EHC68_RS23815	COG4989	oxidoreductase activity
EHC68_RS23830	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EHC68_RS23830	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EHC68_RS23835	COG0516	GMP reductase activity
EHC68_RS23840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC68_RS23900	COG0500	methyltransferase
EHC68_RS23910	COG3474	cytochrome
EHC68_RS23920	COG0789	Transcriptional regulator
EHC68_RS23925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EHC68_RS23930	COG0384	phenazine biosynthesis protein PhzF
EHC68_RS23940	COG1294	oxidase, subunit
EHC68_RS23945	COG1271	oxidase subunit
EHC68_RS23950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC68_RS23955	COG0110	maltose O-acetyltransferase activity
EHC68_RS23965	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EHC68_RS23965	COG3264	Mechanosensitive ion channel
EHC68_RS23980	COG2205	protein histidine kinase activity
EHC68_RS23980	COG4999	Histidine kinase
EHC68_RS23980	COG3437	response regulator, receiver
EHC68_RS23980	COG3850	Histidine kinase
EHC68_RS24000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EHC68_RS24005	COG1960	acyl-CoA dehydrogenase activity
EHC68_RS24015	COG0183	Belongs to the thiolase family
EHC68_RS24025	COG1960	acyl-CoA dehydrogenase activity
EHC68_RS24030	COG1024	Enoyl-CoA hydratase
EHC68_RS24045	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_RS24055	COG3706	GGDEF domain
EHC68_RS24060	COG1309	transcriptional regulator
EHC68_RS24065	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_RS24080	COG4176	ABC-type proline glycine betaine transport system permease component
EHC68_RS24085	COG4175	Glycine betaine
EHC68_RS24085	COG0517	IMP dehydrogenase activity
EHC68_RS24100	COG0330	HflC and HflK could
EHC68_RS24110	COG5001	Diguanylate cyclase
EHC68_RS24110	COG3300	MHYT domain
EHC68_RS24130	COG2205	protein histidine kinase activity
EHC68_RS24130	COG0784	Response regulator, receiver
EHC68_RS24190	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHC68_RS24195	COG5001	Diguanylate cyclase
EHC68_RS24200	COG1869	D-ribose catabolic process
EHC68_RS24205	COG1129	ABC transporter
EHC68_RS24210	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHC68_RS24215	COG1879	ABC-type sugar transport system periplasmic component
EHC68_RS24220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC68_RS24225	COG1609	Transcriptional regulator
EHC68_RS24240	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EHC68_RS24260	COG0745	RESPONSE REGULATOR receiver
EHC68_RS24275	COG1785	Belongs to the alkaline phosphatase family
EHC68_RS24295	COG3706	GGDEF domain
EHC68_RS24295	COG0745	RESPONSE REGULATOR receiver
EHC68_RS24305	COG0814	amino acid
EHC68_RS24315	COG0243	molybdopterin cofactor binding
EHC68_RS24320	COG1648	precorrin-2 dehydrogenase activity
EHC68_RS24320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EHC68_RS24340	COG3707	response regulator
EHC68_RS24350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHC68_RS24355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHC68_RS24360	COG1116	anion transmembrane transporter activity
EHC68_RS24365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC68_RS24365	COG2146	nitrite reductase [NAD(P)H] activity
EHC68_RS24420	COG2815	serine threonine protein kinase
EHC68_RS24420	COG0515	serine threonine protein kinase
EHC68_RS24455	COG0631	protein serine/threonine phosphatase activity
EHC68_RS24510	COG3501	Rhs element vgr protein
EHC68_RS24525	COG0420	3'-5' exonuclease activity
EHC68_RS24550	COG3040	lipid binding
EHC68_RS24560	COG2814	Major facilitator Superfamily
EHC68_RS24570	COG1288	antiporter activity
EHC68_RS24585	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EHC68_RS24600	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EHC68_RS24620	COG0583	DNA-binding transcription factor activity
EHC68_RS24625	COG0277	FAD linked oxidase domain protein
EHC68_RS24645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC68_RS24690	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC68_RS24690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC68_RS24730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC68_RS24735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC68_RS24740	COG2146	nitrite reductase [NAD(P)H] activity
EHC68_RS24745	COG2116	formate transmembrane transporter activity
EHC68_RS24765	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EHC68_RS24795	COG0534	Mate efflux family protein
EHC68_RS24805	COG2814	Major facilitator Superfamily
EHC68_RS24810	COG3118	belongs to the thioredoxin family
EHC68_RS24815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHC68_RS24840	COG2271	Major facilitator Superfamily
EHC68_RS24845	COG3851	Histidine kinase
EHC68_RS24850	COG2197	response regulator
EHC68_RS24860	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHC68_RS24865	COG0583	DNA-binding transcription factor activity
EHC68_RS24875	COG0243	molybdopterin cofactor binding
EHC68_RS24905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC68_RS24920	COG1328	CTP reductase activity
EHC68_RS24925	COG0602	queuosine metabolic process
EHC68_RS24930	COG0534	Mate efflux family protein
EHC68_RS24950	COG4067	protein conserved in archaea
EHC68_RS24950	COG0189	ligase activity
EHC68_RS24960	COG3111	PFAM Bacterial OB fold (BOF) protein
EHC68_RS24965	COG1492	cobalamin metabolic process
EHC68_RS24970	COG0725	ABC transporter, periplasmic molybdate-binding protein
EHC68_RS24975	COG4149	molybdate abc transporter
EHC68_RS24980	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EHC68_RS24990	COG3706	GGDEF domain
EHC68_RS24990	COG5001	Diguanylate cyclase
EHC68_RS24990	COG2203	Gaf domain
EHC68_RS24990	COG4251	negative regulation of phosphorylation
EHC68_RS25000	COG3706	GGDEF domain
EHC68_RS25000	COG0745	RESPONSE REGULATOR receiver
EHC68_RS25015	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EHC68_RS25020	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EHC68_RS25045	COG3140	Belongs to the UPF0181 family
EHC68_RS25050	COG0589	response to stress
EHC68_RS25060	COG0583	DNA-binding transcription factor activity
EHC68_RS25080	COG0023	Translation Initiation Factor
EHC68_RS25090	COG1181	Belongs to the D-alanine--D-alanine ligase family
EHC68_RS25100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC68_RS25100	COG1042	CoA-binding domain protein
EHC68_RS25100	COG0045	succinate-CoA ligase (ADP-forming) activity
EHC68_RS25105	COG0583	DNA-binding transcription factor activity
EHC68_RS25110	COG1629	transport
EHC68_RS25110	COG4771	TonB-dependent receptor
EHC68_RS25120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EHC68_RS25125	COG3447	MASE1 domain protein
EHC68_RS25125	COG5001	Diguanylate cyclase
EHC68_RS25125	COG5002	protein histidine kinase activity
EHC68_RS25130	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EHC68_RS25135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EHC68_RS25140	COG1984	allophanate hydrolase subunit 2
EHC68_RS25150	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EHC68_RS25155	COG4181	ATPase activity
EHC68_RS25170	COG5001	Diguanylate cyclase
EHC68_RS25170	COG3300	MHYT domain
EHC68_RS25180	COG0484	heat shock protein binding
EHC68_RS25205	COG4533	DNA binding
EHC68_RS25215	COG2050	protein possibly involved in aromatic compounds catabolism
EHC68_RS25230	COG2067	long-chain fatty acid transport protein
EHC68_RS25235	COG2267	carboxylic ester hydrolase activity
EHC68_RS25250	COG0861	Integral membrane protein TerC family
EHC68_RS25255	COG0737	Belongs to the 5'-nucleotidase family
EHC68_RS25260	COG3593	DNA synthesis involved in DNA repair
EHC68_RS25270	COG0583	DNA-binding transcription factor activity
EHC68_RS25275	COG2116	formate transmembrane transporter activity
EHC68_RS25280	COG2353	YceI-like domain
EHC68_RS25285	COG3038	cytochrome b561
EHC68_RS25300	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EHC68_RS25305	COG0513	Belongs to the DEAD box helicase family
EHC68_RS25310	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
EHC68_RS25320	COG0840	transmembrane signaling receptor activity
EHC68_RS25325	COG0546	phosphoglycolate phosphatase activity
EHC68_RS25335	COG3437	response regulator, receiver
EHC68_RS25335	COG0784	Response regulator, receiver
EHC68_RS25355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC68_RS25360	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EHC68_RS25365	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC68_RS25380	COG2207	Transcriptional regulator
EHC68_RS25385	COG1979	alcohol dehydrogenase
EHC68_RS25405	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC68_RS25410	COG2271	Major facilitator Superfamily
EHC68_RS25415	COG0469	pyruvate kinase activity
EHC68_RS25420	COG1126	abc transporter atp-binding protein
EHC68_RS25425	COG0765	amino acid transport
EHC68_RS25430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_RS25435	COG0765	amino acid transport
EHC68_RS25440	COG2200	EAL domain
EHC68_RS25440	COG2203	Gaf domain
EHC68_RS25440	COG2199	diguanylate cyclase activity
EHC68_RS25460	COG1609	Transcriptional regulator
EHC68_RS25465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_RS25465	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_RS25470	COG1105	Belongs to the carbohydrate kinase PfkB family
EHC68_RS25475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC68_RS25475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC68_RS25475	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EHC68_RS25515	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHC68_RS25520	COG0509	glycine decarboxylation via glycine cleavage system
EHC68_RS25525	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHC68_RS25525	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHC68_RS25545	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EHC68_RS25550	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHC68_RS25555	COG0583	DNA-binding transcription factor activity
EHC68_RS25560	COG2176	DNA-directed DNA polymerase activity
EHC68_RS25605	COG0242	peptide deformylase activity
EHC68_RS25625	COG2239	Acts as a magnesium transporter
EHC68_RS25645	COG0346	lactoylglutathione lyase activity
EHC68_RS25650	COG1902	pentaerythritol trinitrate reductase activity
EHC68_RS25675	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EHC68_RS25685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EHC68_RS25685	COG0069	glutamate synthase activity
EHC68_RS25695	COG4565	transcriptional regulatory protein
EHC68_RS25700	COG3290	protein histidine kinase activity
EHC68_RS25705	COG0471	metal ion transport
EHC68_RS25735	COG2076	Multidrug Resistance protein
EHC68_RS25750	COG0671	phosphoesterase, PA-phosphatase related
EHC68_RS25765	COG2962	Rard protein
EHC68_RS25785	COG0784	Response regulator, receiver
EHC68_RS25785	COG0835	chemotaxis
EHC68_RS25810	COG2197	response regulator
EHC68_RS25820	COG3706	GGDEF domain
EHC68_RS25825	COG2197	response regulator
EHC68_RS25830	COG3300	MHYT domain
EHC68_RS25830	COG5001	Diguanylate cyclase
EHC68_RS25845	COG0583	DNA-binding transcription factor activity
EHC68_RS25850	COG0583	DNA-binding transcription factor activity
EHC68_RS25910	COG4964	Belongs to the GSP D family
EHC68_RS25935	COG2207	Transcriptional regulator
EHC68_RS25965	COG0582	viral genome integration into host DNA
EHC68_RS25995	COG0514	ATP-dependent DNA helicase (RecQ)
EHC68_RS26010	COG0737	Belongs to the 5'-nucleotidase family
EHC68_RS26015	COG1940	carbohydrate kinase activity
EHC68_RS26025	COG0477	Major facilitator Superfamily
EHC68_RS26025	COG2814	Major facilitator Superfamily
EHC68_RS26030	COG0457	Tetratricopeptide repeat
EHC68_RS26110	COG2801	Transposase and inactivated derivatives
EHC68_RS26190	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EHC68_RS26205	COG1943	Transposase
EHC68_RS26210	COG0840	transmembrane signaling receptor activity
EHC68_RS26225	COG1484	DNA-dependent DNA replication
EHC68_RS26260	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EHC68_RS26615	COG0419	ATPase involved in DNA repair
EHC68_RS26640	COG1192	Involved in chromosome partitioning
EHC68_RS26665	COG5268	conjugation