locus-tag	class	description
EHC69_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EHC69_RS00010	COG0592	DNA-directed DNA polymerase activity
EHC69_RS00065	COG2119	membrane
EHC69_RS00075	COG0425	Belongs to the sulfur carrier protein TusA family
EHC69_RS00090	COG0604	alcohol dehydrogenase
EHC69_RS00095	COG0183	Belongs to the thiolase family
EHC69_RS00100	COG1024	Enoyl-CoA hydratase
EHC69_RS00100	COG1250	3-hydroxyacyl-CoA dehydrogenase
EHC69_RS00105	COG1739	Uncharacterized protein family UPF0029
EHC69_RS00110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC69_RS00155	COG0583	DNA-binding transcription factor activity
EHC69_RS00160	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EHC69_RS00165	COG2960	long-chain fatty acid transporting porin activity
EHC69_RS00175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC69_RS00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC69_RS00245	COG4172	Belongs to the ABC transporter superfamily
EHC69_RS00250	COG0747	negative chemotaxis
EHC69_RS00260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC69_RS00300	COG1609	Transcriptional regulator
EHC69_RS00305	COG0583	DNA-binding transcription factor activity
EHC69_RS00315	COG2076	Multidrug Resistance protein
EHC69_RS00320	COG0129	dihydroxy-acid dehydratase activity
EHC69_RS00325	COG3265	gluconokinase activity
EHC69_RS00330	COG2610	gluconate transmembrane transporter activity
EHC69_RS00335	COG0800	Aldolase
EHC69_RS00340	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EHC69_RS00345	COG0583	DNA-binding transcription factor activity
EHC69_RS00350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC69_RS00355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EHC69_RS00360	COG0339	signal peptide processing
EHC69_RS00365	COG1522	sequence-specific DNA binding
EHC69_RS00370	COG5001	Diguanylate cyclase
EHC69_RS00370	COG5002	protein histidine kinase activity
EHC69_RS00375	COG0742	ribosomal rna small subunit methyltransferase
EHC69_RS00390	COG0589	response to stress
EHC69_RS00395	COG1528	Iron-storage protein
EHC69_RS00405	COG2081	HI0933 family
EHC69_RS00415	COG2823	Periplasmic or secreted lipoprotein
EHC69_RS00465	COG0628	permease
EHC69_RS00480	COG1322	Protein conserved in bacteria
EHC69_RS00485	COG2226	methyltransferase
EHC69_RS00490	COG3165	ubiquinone biosynthetic process from chorismate
EHC69_RS00495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EHC69_RS00500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHC69_RS00510	COG0805	protein transport
EHC69_RS00520	COG0084	hydrolase, TatD family'
EHC69_RS00545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC69_RS00545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC69_RS00555	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EHC69_RS00585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHC69_RS00590	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHC69_RS00600	COG2204	response regulator
EHC69_RS00605	COG3852	Histidine kinase
EHC69_RS00615	COG0174	glutamine synthetase
EHC69_RS00635	COG1295	ribonuclease BN
EHC69_RS00640	COG1490	D-aminoacyl-tRNA deacylase activity
EHC69_RS00645	COG0456	acetyltransferase
EHC69_RS00655	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EHC69_RS00660	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EHC69_RS00665	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EHC69_RS00670	COG3031	protein transport across the cell outer membrane
EHC69_RS00680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC69_RS00685	COG1459	type II secretion system
EHC69_RS00690	COG2165	general secretion pathway protein
EHC69_RS00695	COG2165	general secretion pathway protein
EHC69_RS00700	COG2165	general secretion pathway protein
EHC69_RS00705	COG4795	General secretion pathway protein
EHC69_RS00710	COG3156	type II secretion system protein K
EHC69_RS00715	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EHC69_RS00720	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EHC69_RS00730	COG1218	3'(2'),5'-bisphosphate nucleotidase
EHC69_RS00735	COG0494	nUDIX hydrolase
EHC69_RS00740	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EHC69_RS00740	COG0316	Belongs to the HesB IscA family
EHC69_RS00745	COG1040	competence protein
EHC69_RS00750	COG0596	Alpha beta hydrolase
EHC69_RS00760	COG2183	response to ionizing radiation
EHC69_RS00770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC69_RS00780	COG0745	RESPONSE REGULATOR receiver
EHC69_RS00785	COG2205	protein histidine kinase activity
EHC69_RS00790	COG2233	PERMEase
EHC69_RS00795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EHC69_RS00800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC69_RS00805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHC69_RS00810	COG1758	RNA polymerase activity
EHC69_RS00815	COG0194	GDP metabolic process
EHC69_RS00830	COG0848	biopolymer transport protein
EHC69_RS00835	COG0811	peptide transport
EHC69_RS00860	COG4174	ABC transporter (Permease)
EHC69_RS00865	COG4239	(ABC) transporter, permease
EHC69_RS00870	COG0747	negative chemotaxis
EHC69_RS00875	COG0444	Belongs to the ABC transporter superfamily
EHC69_RS00880	COG4608	Belongs to the ABC transporter superfamily
EHC69_RS00910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC69_RS00920	COG1561	YicC-like family, N-terminal region
EHC69_RS00925	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EHC69_RS00930	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EHC69_RS00935	COG1560	Kdo2-lipid A biosynthetic process
EHC69_RS00940	COG1309	transcriptional regulator
EHC69_RS00945	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EHC69_RS00955	COG0840	transmembrane signaling receptor activity
EHC69_RS00960	COG2003	Belongs to the UPF0758 family
EHC69_RS00965	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EHC69_RS00980	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EHC69_RS00995	COG0438	transferase activity, transferring glycosyl groups
EHC69_RS01000	COG0463	Glycosyl transferase, family 2
EHC69_RS01005	COG0859	PFAM glycosyl transferase family 9
EHC69_RS01010	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EHC69_RS01015	COG3642	lipopolysaccharide core region biosynthetic process
EHC69_RS01035	COG0110	maltose O-acetyltransferase activity
EHC69_RS01040	COG2030	dehydratase
EHC69_RS01060	COG0438	transferase activity, transferring glycosyl groups
EHC69_RS01060	COG0297	glycogen (starch) synthase activity
EHC69_RS01070	COG1519	Transferase
EHC69_RS01075	COG0859	PFAM glycosyl transferase family 9
EHC69_RS01080	COG1560	Kdo2-lipid A biosynthetic process
EHC69_RS01090	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC69_RS01150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EHC69_RS01150	COG1215	transferase activity, transferring glycosyl groups
EHC69_RS01160	COG0463	Glycosyl transferase, family 2
EHC69_RS01170	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EHC69_RS01175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EHC69_RS01195	COG1482	cell wall glycoprotein biosynthetic process
EHC69_RS01205	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EHC69_RS01245	COG2801	Transposase and inactivated derivatives
EHC69_RS01255	COG3547	Transposase (IS116 IS110 IS902 family)
EHC69_RS01265	COG0149	triose-phosphate isomerase activity
EHC69_RS01290	COG1494	fructose-1,6-bisphosphatase
EHC69_RS01300	COG3074	FtsZ-dependent cytokinesis
EHC69_RS01305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EHC69_RS01310	COG1575	Belongs to the MenA family. Type 1 subfamily
EHC69_RS01340	COG2003	Belongs to the UPF0758 family
EHC69_RS01355	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EHC69_RS01360	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EHC69_RS01370	COG1609	Transcriptional regulator
EHC69_RS01375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHC69_RS01385	COG0254	rRNA binding
EHC69_RS01395	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EHC69_RS01400	COG0088	Forms part of the polypeptide exit tunnel
EHC69_RS01410	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EHC69_RS01415	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EHC69_RS01420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EHC69_RS01425	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EHC69_RS01435	COG0255	Belongs to the universal ribosomal protein uL29 family
EHC69_RS01440	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EHC69_RS01445	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EHC69_RS01450	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EHC69_RS01455	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EHC69_RS01460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHC69_RS01465	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EHC69_RS01470	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EHC69_RS01485	COG1841	ribosomal large subunit assembly
EHC69_RS01490	COG0200	Binds to the 23S rRNA
EHC69_RS01495	COG0201	protein transport
EHC69_RS01505	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EHC69_RS01510	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EHC69_RS01520	COG0202	RNA polymerase activity
EHC69_RS01525	COG0203	ribosomal protein L17
EHC69_RS01535	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC69_RS01545	COG2153	protein acetylation
EHC69_RS01550	COG0513	Belongs to the DEAD box helicase family
EHC69_RS01560	COG0737	Belongs to the 5'-nucleotidase family
EHC69_RS01565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EHC69_RS01565	COG1648	precorrin-2 dehydrogenase activity
EHC69_RS01570	COG0175	sulfate reduction
EHC69_RS01575	COG2895	sulfate adenylyltransferase (ATP) activity
EHC69_RS01585	COG0471	metal ion transport
EHC69_RS01585	COG3273	potassium ion transport
EHC69_RS01590	COG0529	Catalyzes the synthesis of activated sulfate
EHC69_RS01610	COG4181	ATPase activity
EHC69_RS01625	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EHC69_RS01635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC69_RS01640	COG0729	surface antigen
EHC69_RS01650	COG2105	PFAM AIG2 family protein
EHC69_RS01660	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EHC69_RS01665	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EHC69_RS01675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EHC69_RS01680	COG0163	prenyltransferase activity
EHC69_RS01685	COG4143	(ABC) transporter
EHC69_RS01690	COG1178	ABC-type Fe3 transport system permease component
EHC69_RS01695	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EHC69_RS01730	COG0039	L-malate dehydrogenase activity
EHC69_RS01740	COG0142	geranyltranstransferase activity
EHC69_RS01745	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EHC69_RS01755	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EHC69_RS01760	COG2966	Psort location CytoplasmicMembrane, score
EHC69_RS01775	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EHC69_RS01780	COG2967	ApaG domain
EHC69_RS01785	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EHC69_RS01790	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EHC69_RS01795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC69_RS01800	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EHC69_RS01805	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EHC69_RS01815	COG0066	3-isopropylmalate dehydratase activity
EHC69_RS01820	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHC69_RS01825	COG0473	3-isopropylmalate dehydrogenase activity
EHC69_RS01830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHC69_RS01855	COG0583	DNA-binding transcription factor activity
EHC69_RS01860	COG1022	Amp-dependent synthetase and ligase
EHC69_RS01865	COG0028	Belongs to the TPP enzyme family
EHC69_RS01870	COG0440	acetolactate synthase activity
EHC69_RS01875	COG3706	GGDEF domain
EHC69_RS01885	COG0469	pyruvate kinase activity
EHC69_RS01895	COG1349	DNA-binding transcription factor activity
EHC69_RS01900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EHC69_RS01915	COG5002	protein histidine kinase activity
EHC69_RS01920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC69_RS01925	COG3722	fumarate hydratase activity
EHC69_RS01930	COG0246	Mannitol dehydrogenase
EHC69_RS01935	COG2213	PTS system mannitol-specific
EHC69_RS01935	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC69_RS01970	COG1464	Belongs to the NlpA lipoprotein family
EHC69_RS01980	COG3339	Conserved Protein
EHC69_RS01990	COG2801	Transposase and inactivated derivatives
EHC69_RS02095	COG0494	nUDIX hydrolase
EHC69_RS02105	COG1566	PFAM secretion protein HlyD family protein
EHC69_RS02240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHC69_RS02245	COG0358	DNA primase activity
EHC69_RS02250	COG1610	YqeY-like protein
EHC69_RS02255	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EHC69_RS02260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EHC69_RS02265	COG0596	Alpha beta hydrolase
EHC69_RS02270	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EHC69_RS02275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EHC69_RS02285	COG1968	undecaprenyl-diphosphatase activity
EHC69_RS02290	COG0617	tRNA 3'-terminal CCA addition
EHC69_RS02295	COG3409	Peptidoglycan-binding domain 1 protein
EHC69_RS02295	COG3267	Type II secretory pathway component ExeA
EHC69_RS02305	COG4991	sh3 domain protein
EHC69_RS02310	COG0306	phosphate transporter
EHC69_RS02315	COG1392	Phosphate transport regulator
EHC69_RS02320	COG3025	triphosphatase activity
EHC69_RS02335	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EHC69_RS02340	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EHC69_RS02340	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EHC69_RS02345	COG1538	Outer membrane efflux protein
EHC69_RS02350	COG0494	nUDIX hydrolase
EHC69_RS02355	COG3151	Protein conserved in bacteria
EHC69_RS02365	COG3150	esterase
EHC69_RS02370	COG0187	DNA topoisomerase II activity
EHC69_RS02375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHC69_RS02380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHC69_RS02390	COG3105	Protein conserved in bacteria
EHC69_RS02400	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EHC69_RS02410	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EHC69_RS02415	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EHC69_RS02420	COG0723	plastoquinol--plastocyanin reductase activity
EHC69_RS02425	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EHC69_RS02430	COG2857	Cytochrome c1
EHC69_RS02435	COG0625	glutathione transferase activity
EHC69_RS02440	COG2969	positive regulation of protein catabolic process
EHC69_RS02445	COG2823	Periplasmic or secreted lipoprotein
EHC69_RS02450	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EHC69_RS02455	COG0792	nuclease activity
EHC69_RS02465	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EHC69_RS02480	COG0275	rRNA processing
EHC69_RS02485	COG3116	cell division
EHC69_RS02490	COG0768	penicillin binding
EHC69_RS02495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EHC69_RS02500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EHC69_RS02505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EHC69_RS02510	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EHC69_RS02515	COG0772	Belongs to the SEDS family
EHC69_RS02520	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHC69_RS02525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EHC69_RS02530	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EHC69_RS02535	COG0849	cell division
EHC69_RS02540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EHC69_RS02545	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EHC69_RS02555	COG0653	protein targeting
EHC69_RS02560	COG0494	nUDIX hydrolase
EHC69_RS02565	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EHC69_RS02570	COG0505	Belongs to the CarA family
EHC69_RS02575	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EHC69_RS02590	COG0730	response to heat
EHC69_RS02595	COG0583	DNA-binding transcription factor activity
EHC69_RS02600	COG2860	membrane
EHC69_RS02605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHC69_RS02615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHC69_RS02625	COG0493	'glutamate synthase
EHC69_RS02630	COG0070	glutamate synthase
EHC69_RS02630	COG0067	glutamate synthase
EHC69_RS02630	COG0069	glutamate synthase activity
EHC69_RS02640	COG0070	glutamate synthase
EHC69_RS02640	COG0069	glutamate synthase activity
EHC69_RS02640	COG0067	glutamate synthase
EHC69_RS02645	COG1242	4 iron, 4 sulfur cluster binding
EHC69_RS02650	COG3706	GGDEF domain
EHC69_RS02650	COG4251	negative regulation of phosphorylation
EHC69_RS02650	COG5001	Diguanylate cyclase
EHC69_RS02650	COG2203	Gaf domain
EHC69_RS02655	COG2198	Histidine kinase
EHC69_RS02655	COG5002	protein histidine kinase activity
EHC69_RS02655	COG0784	Response regulator, receiver
EHC69_RS02665	COG0745	RESPONSE REGULATOR receiver
EHC69_RS02680	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EHC69_RS02695	COG0083	homoserine kinase activity
EHC69_RS02700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EHC69_RS02705	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
EHC69_RS02710	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EHC69_RS02720	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EHC69_RS02735	COG1115	amino acid carrier protein
EHC69_RS02740	COG3022	response to hydroperoxide
EHC69_RS02745	COG0513	Belongs to the DEAD box helicase family
EHC69_RS02750	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EHC69_RS02760	COG0716	FMN binding
EHC69_RS02770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC69_RS02775	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EHC69_RS02785	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EHC69_RS02800	COG0667	Aldo Keto reductase
EHC69_RS02810	COG3066	DNA modification
EHC69_RS02820	COG0494	nUDIX hydrolase
EHC69_RS02830	COG0730	response to heat
EHC69_RS02835	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EHC69_RS02840	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EHC69_RS02850	COG1283	sodium-dependent phosphate transmembrane transporter activity
EHC69_RS02855	COG0583	DNA-binding transcription factor activity
EHC69_RS02865	COG0640	Transcriptional regulator
EHC69_RS02875	COG0268	Binds directly to 16S ribosomal RNA
EHC69_RS02880	COG0728	peptidoglycan biosynthetic process
EHC69_RS02885	COG0196	riboflavin kinase activity
EHC69_RS02890	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHC69_RS02895	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EHC69_RS02900	COG1047	Peptidyl-prolyl cis-trans
EHC69_RS02905	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EHC69_RS02910	COG3279	Response regulator of the LytR AlgR family
EHC69_RS02915	COG3275	phosphorelay sensor kinase activity
EHC69_RS02920	COG1966	Carbon starvation protein
EHC69_RS02935	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHC69_RS02940	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EHC69_RS02945	COG1472	Belongs to the glycosyl hydrolase 3 family
EHC69_RS02950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC69_RS02955	COG1605	Chorismate mutase
EHC69_RS02955	COG0287	Prephenate dehydrogenase
EHC69_RS02960	COG0739	heme binding
EHC69_RS02975	COG0488	(ABC) transporter
EHC69_RS02985	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EHC69_RS02990	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EHC69_RS02995	COG0077	Prephenate dehydratase
EHC69_RS02995	COG1605	Chorismate mutase
EHC69_RS03000	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHC69_RS03005	COG0741	lytic transglycosylase activity
EHC69_RS03010	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC69_RS03015	COG0564	pseudouridine synthase activity
EHC69_RS03025	COG0542	response to heat
EHC69_RS03085	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EHC69_RS03095	COG2974	May be involved in recombination
EHC69_RS03100	COG0745	RESPONSE REGULATOR receiver
EHC69_RS03105	COG5002	protein histidine kinase activity
EHC69_RS03115	COG0248	Ppx GppA phosphatase
EHC69_RS03120	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EHC69_RS03130	COG0581	inorganic phosphate transmembrane transporter activity
EHC69_RS03135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EHC69_RS03140	COG0704	Plays a role in the regulation of phosphate uptake
EHC69_RS03150	COG3142	Participates in the control of copper homeostasis
EHC69_RS03155	COG0450	alkyl hydroperoxide reductase
EHC69_RS03160	COG0583	DNA-binding transcription factor activity
EHC69_RS03170	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EHC69_RS03180	COG0517	IMP dehydrogenase activity
EHC69_RS03190	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EHC69_RS03195	COG0343	queuine tRNA-ribosyltransferase activity
EHC69_RS03200	COG1862	Preprotein translocase
EHC69_RS03205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC69_RS03210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC69_RS03220	COG0483	inositol monophosphate 1-phosphatase activity
EHC69_RS03235	COG1104	cysteine desulfurase activity
EHC69_RS03240	COG0822	iron-sulfur transferase activity
EHC69_RS03250	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EHC69_RS03255	COG0443	Heat shock 70 kDa protein
EHC69_RS03260	COG0633	Ferredoxin
EHC69_RS03265	COG2975	iron-sulfur cluster assembly
EHC69_RS03270	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHC69_RS03275	COG0105	UTP biosynthetic process
EHC69_RS03280	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EHC69_RS03295	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EHC69_RS03300	COG0124	histidyl-tRNA synthetase
EHC69_RS03305	COG2976	Protein conserved in bacteria
EHC69_RS03310	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC69_RS03315	COG1160	GTP binding
EHC69_RS03330	COG1570	exodeoxyribonuclease VII activity
EHC69_RS03335	COG0517	IMP dehydrogenase activity
EHC69_RS03335	COG0516	GMP reductase activity
EHC69_RS03340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EHC69_RS03340	COG0519	Catalyzes the synthesis of GMP from XMP
EHC69_RS03345	COG1757	Na H antiporter
EHC69_RS03355	COG1584	GPR1 FUN34 yaaH family protein
EHC69_RS03365	COG1115	amino acid carrier protein
EHC69_RS03400	COG2873	o-acetylhomoserine
EHC69_RS03405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EHC69_RS03425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHC69_RS03425	COG3153	acetyltransferase
EHC69_RS03430	COG0583	DNA-binding transcription factor activity
EHC69_RS03450	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EHC69_RS03455	COG2867	negative regulation of translational initiation
EHC69_RS03460	COG2914	Belongs to the UPF0125 (RnfH) family
EHC69_RS03465	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC69_RS03470	COG0497	DNA recombination
EHC69_RS03480	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHC69_RS03485	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EHC69_RS03495	COG0443	Heat shock 70 kDa protein
EHC69_RS03500	COG0484	heat shock protein binding
EHC69_RS03540	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EHC69_RS03545	COG0590	tRNA wobble adenosine to inosine editing
EHC69_RS03555	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EHC69_RS03560	COG0047	phosphoribosylformylglycinamidine synthase activity
EHC69_RS03560	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHC69_RS03585	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC69_RS03590	COG2252	PERMEase
EHC69_RS03595	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EHC69_RS03610	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHC69_RS03615	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EHC69_RS03620	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EHC69_RS03625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC69_RS03625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC69_RS03645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHC69_RS03650	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EHC69_RS03655	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EHC69_RS03660	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EHC69_RS03665	COG0142	geranyltranstransferase activity
EHC69_RS03670	COG1722	exodeoxyribonuclease VII activity
EHC69_RS03675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EHC69_RS03680	COG2885	chlorophyll binding
EHC69_RS03685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC69_RS03685	COG0301	tRNA thio-modification
EHC69_RS03690	COG0583	DNA-binding transcription factor activity
EHC69_RS03700	COG2363	Small membrane protein
EHC69_RS03705	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EHC69_RS03715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC69_RS03720	COG1611	Belongs to the LOG family
EHC69_RS03725	COG3706	GGDEF domain
EHC69_RS03735	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHC69_RS03735	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHC69_RS03745	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
EHC69_RS03750	COG1464	Belongs to the NlpA lipoprotein family
EHC69_RS03755	COG2011	ABC-type metal ion transport system permease component
EHC69_RS03760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EHC69_RS03770	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EHC69_RS03780	COG1263	PTS System
EHC69_RS03780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC69_RS03785	COG0366	Alpha amylase catalytic
EHC69_RS03800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHC69_RS03805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHC69_RS03810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EHC69_RS03815	COG0321	lipoyl(octanoyl) transferase activity
EHC69_RS03820	COG2921	Belongs to the UPF0250 family
EHC69_RS03825	COG1686	Belongs to the peptidase S11 family
EHC69_RS03830	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EHC69_RS03835	COG0772	Belongs to the SEDS family
EHC69_RS03840	COG0768	penicillin binding
EHC69_RS03845	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EHC69_RS03850	COG0799	negative regulation of ribosome biogenesis
EHC69_RS03855	COG1466	dna polymerase III delta subunit
EHC69_RS03860	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EHC69_RS03865	COG0495	leucyl-tRNA aminoacylation
EHC69_RS03870	COG2888	peptidyl-tyrosine sulfation
EHC69_RS03875	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EHC69_RS03880	COG4535	Mg2 and Co2 transporter CorC
EHC69_RS03885	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EHC69_RS03890	COG1702	phosphate starvation-inducible protein PhoH
EHC69_RS03895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHC69_RS03905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC69_RS04020	COG0012	GTP binding
EHC69_RS04025	COG0193	aminoacyl-tRNA hydrolase activity
EHC69_RS04030	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EHC69_RS04035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EHC69_RS04040	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EHC69_RS04045	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EHC69_RS04050	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EHC69_RS04055	COG2890	protein-(glutamine-N5) methyltransferase activity
EHC69_RS04060	COG3094	Invasion gene expression up-regulator, SirB
EHC69_RS04065	COG2912	Transglutaminase-like superfamily
EHC69_RS04070	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EHC69_RS04075	COG0737	Belongs to the 5'-nucleotidase family
EHC69_RS04085	COG1187	pseudouridine synthase activity
EHC69_RS04090	COG2840	Smr protein MutS2
EHC69_RS04130	COG2217	Heavy metal translocating P-type atpase
EHC69_RS04130	COG2608	mercury ion transmembrane transporter activity
EHC69_RS04145	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC69_RS04150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC69_RS04210	COG0784	Response regulator, receiver
EHC69_RS04210	COG0835	chemotaxis
EHC69_RS04215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EHC69_RS04220	COG1815	bacterial-type flagellum-dependent cell motility
EHC69_RS04225	COG1558	bacterial-type flagellum-dependent cell motility
EHC69_RS04230	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EHC69_RS04235	COG1749	Flagellar hook protein flgE
EHC69_RS04245	COG4787	bacterial-type flagellum-dependent cell motility
EHC69_RS04250	COG4786	Flagellar basal body rod
EHC69_RS04255	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EHC69_RS04260	COG1706	bacterial-type flagellum-dependent cell motility
EHC69_RS04265	COG3951	Flagellar rod assembly protein muramidase FlgJ
EHC69_RS04265	COG1705	Flagellar rod assembly protein muramidase FlgJ
EHC69_RS04275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC69_RS04285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC69_RS04295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC69_RS04300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC69_RS04310	COG2190	(PTS) system
EHC69_RS04315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHC69_RS04320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC69_RS04330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EHC69_RS04335	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EHC69_RS04340	COG3115	cell septum assembly
EHC69_RS04345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHC69_RS04370	COG0330	HflC and HflK could
EHC69_RS04375	COG3118	belongs to the thioredoxin family
EHC69_RS04385	COG0300	oxidoreductase activity
EHC69_RS04390	COG1090	epimerase
EHC69_RS04420	COG0622	Phosphoesterase
EHC69_RS04440	COG3710	Transcriptional regulator
EHC69_RS04445	COG0326	Molecular chaperone. Has ATPase activity
EHC69_RS04450	COG0563	adenylate kinase activity
EHC69_RS04455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EHC69_RS04460	COG3104	oligopeptide transport
EHC69_RS04465	COG0250	Participates in transcription elongation, termination and antitermination
EHC69_RS04470	COG0367	asparagine synthase
EHC69_RS04475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EHC69_RS04475	COG4651	solute:proton antiporter activity
EHC69_RS04480	COG1940	carbohydrate kinase activity
EHC69_RS04480	COG1846	Transcriptional regulator
EHC69_RS04485	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EHC69_RS04495	COG2190	(PTS) system
EHC69_RS04495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC69_RS04495	COG1263	PTS System
EHC69_RS04500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC69_RS04505	COG0735	belongs to the Fur family
EHC69_RS04515	COG0716	FMN binding
EHC69_RS04525	COG0596	Alpha beta hydrolase
EHC69_RS04530	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EHC69_RS04535	COG0033	Phosphoglucomutase
EHC69_RS04545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EHC69_RS04555	COG2009	succinate dehydrogenase
EHC69_RS04560	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EHC69_RS04565	COG1053	succinate dehydrogenase
EHC69_RS04570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EHC69_RS04575	COG0567	Dehydrogenase, E1 component
EHC69_RS04580	COG0508	dehydrogenase complex catalyzes the overall conversion of
EHC69_RS04585	COG0045	succinate-CoA ligase (ADP-forming) activity
EHC69_RS04595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EHC69_RS04600	COG1121	(ABC) transporter
EHC69_RS04605	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EHC69_RS04610	COG4977	sequence-specific DNA binding
EHC69_RS04625	COG1918	ferrous iron import across plasma membrane
EHC69_RS04645	COG0018	arginyl-trna synthetase
EHC69_RS04655	COG3102	Protein conserved in bacteria
EHC69_RS04660	COG0788	formyltetrahydrofolate deformylase activity
EHC69_RS04665	COG1199	ATP-dependent helicase activity
EHC69_RS04670	COG1214	PFAM Peptidase M22, glycoprotease
EHC69_RS04685	COG2267	carboxylic ester hydrolase activity
EHC69_RS04690	COG0318	PFAM AMP-dependent synthetase and ligase
EHC69_RS04695	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EHC69_RS04700	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EHC69_RS04705	COG2894	cell division
EHC69_RS04710	COG0850	regulation of cytokinetic process
EHC69_RS04715	COG3100	YcgL domain-containing protein
EHC69_RS04720	COG2951	lytic endotransglycosylase activity
EHC69_RS04725	COG0583	DNA-binding transcription factor activity
EHC69_RS04730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC69_RS04735	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EHC69_RS04755	COG1028	Short-chain dehydrogenase reductase Sdr
EHC69_RS04760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC69_RS04765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EHC69_RS04790	COG2986	histidine ammonia-lyase
EHC69_RS04795	COG1216	Glycosyl transferase, family 2
EHC69_RS04800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC69_RS04815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHC69_RS04820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHC69_RS04855	COG1253	flavin adenine dinucleotide binding
EHC69_RS04860	COG0513	Belongs to the DEAD box helicase family
EHC69_RS04865	COG0569	domain protein
EHC69_RS04870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC69_RS04890	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EHC69_RS04895	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EHC69_RS04900	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EHC69_RS04905	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EHC69_RS04915	COG2204	response regulator
EHC69_RS04925	COG0544	peptidyl-prolyl cis-trans isomerase activity
EHC69_RS04935	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EHC69_RS04940	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EHC69_RS04945	COG0776	regulation of translation
EHC69_RS04950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC69_RS04955	COG1555	photosystem II stabilization
EHC69_RS04970	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EHC69_RS04975	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EHC69_RS04980	COG0436	Aminotransferase
EHC69_RS04985	COG1169	isochorismate synthase
EHC69_RS04990	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EHC69_RS04995	COG0596	Alpha beta hydrolase
EHC69_RS05000	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EHC69_RS05005	COG1441	menaquinone biosynthetic process
EHC69_RS05020	COG2855	membrane
EHC69_RS05025	COG0477	Major facilitator Superfamily
EHC69_RS05075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC69_RS05105	COG1522	sequence-specific DNA binding
EHC69_RS05115	COG1946	Acyl-CoA thioesterase
EHC69_RS05120	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EHC69_RS05135	COG2199	diguanylate cyclase activity
EHC69_RS05170	COG1061	Type III restriction enzyme res subunit
EHC69_RS05215	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EHC69_RS05215	COG0515	serine threonine protein kinase
EHC69_RS05230	COG3501	Rhs element vgr protein
EHC69_RS05285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC69_RS05290	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EHC69_RS05295	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EHC69_RS05305	COG0517	IMP dehydrogenase activity
EHC69_RS05305	COG0516	GMP reductase activity
EHC69_RS05335	COG0537	adenosine 5'-monophosphoramidase activity
EHC69_RS05360	COG3150	esterase
EHC69_RS05370	COG1252	NADH dehydrogenase
EHC69_RS05385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EHC69_RS05395	COG4591	ABC-type transport system involved in lipoprotein release permease component
EHC69_RS05400	COG1136	(ABC) transporter
EHC69_RS05405	COG4591	ABC-type transport system involved in lipoprotein release permease component
EHC69_RS05415	COG0658	competence protein
EHC69_RS05415	COG2333	competence protein COMEC
EHC69_RS05420	COG1132	(ABC) transporter
EHC69_RS05425	COG1663	tetraacyldisaccharide 4'-kinase activity
EHC69_RS05435	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EHC69_RS05440	COG2719	SpoVR family
EHC69_RS05445	COG2718	Belongs to the UPF0229 family
EHC69_RS05450	COG2766	serine protein kinase
EHC69_RS05460	COG3013	Belongs to the UPF0304 family
EHC69_RS05470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC69_RS05480	COG1882	Formate acetyltransferase
EHC69_RS05510	COG4215	(ABC) transporter
EHC69_RS05525	COG0708	Exodeoxyribonuclease III
EHC69_RS05535	COG3923	Primosomal replication protein n
EHC69_RS05540	COG0730	response to heat
EHC69_RS05545	COG1199	ATP-dependent helicase activity
EHC69_RS05555	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC69_RS05560	COG1187	pseudouridine synthase activity
EHC69_RS05570	COG1278	Cold shock
EHC69_RS05575	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EHC69_RS05580	COG0542	response to heat
EHC69_RS05590	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EHC69_RS05595	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EHC69_RS05600	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EHC69_RS05610	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EHC69_RS05620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC69_RS05625	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC69_RS05630	COG0297	glycogen (starch) synthase activity
EHC69_RS05650	COG3070	regulator of competence-specific genes
EHC69_RS05655	COG1609	Transcriptional regulator
EHC69_RS05660	COG3381	protein complex oligomerization
EHC69_RS05665	COG0745	RESPONSE REGULATOR receiver
EHC69_RS05670	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EHC69_RS05675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC69_RS05680	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EHC69_RS05685	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EHC69_RS05690	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EHC69_RS05710	COG4067	protein conserved in archaea
EHC69_RS05710	COG0189	ligase activity
EHC69_RS05720	COG0500	methyltransferase
EHC69_RS05725	COG4106	trans-aconitate 2-methyltransferase activity
EHC69_RS05730	COG1801	Protein of unknown function DUF72
EHC69_RS05735	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EHC69_RS05740	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EHC69_RS05745	COG0840	transmembrane signaling receptor activity
EHC69_RS05750	COG0632	four-way junction helicase activity
EHC69_RS05755	COG2255	four-way junction helicase activity
EHC69_RS05760	COG1271	oxidase subunit
EHC69_RS05765	COG1294	oxidase, subunit
EHC69_RS05770	COG4890	Cyd operon protein YbgT
EHC69_RS05780	COG0824	Thioesterase
EHC69_RS05785	COG0811	peptide transport
EHC69_RS05800	COG0823	Involved in the tonB-independent uptake of proteins
EHC69_RS05805	COG2885	chlorophyll binding
EHC69_RS05810	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EHC69_RS05815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EHC69_RS05825	COG3766	membrane
EHC69_RS05835	COG0754	glutathionylspermidine amidase activity
EHC69_RS05845	COG0784	Response regulator, receiver
EHC69_RS05845	COG5002	protein histidine kinase activity
EHC69_RS05850	COG2801	Transposase and inactivated derivatives
EHC69_RS05885	COG0840	transmembrane signaling receptor activity
EHC69_RS05900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC69_RS05905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC69_RS05935	COG3568	Endonuclease Exonuclease Phosphatase
EHC69_RS05950	COG0583	DNA-binding transcription factor activity
EHC69_RS05960	COG0686	Belongs to the AlaDH PNT family
EHC69_RS05970	COG1674	ftsk spoiiie
EHC69_RS05975	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EHC69_RS05980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EHC69_RS05985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EHC69_RS05995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EHC69_RS06000	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EHC69_RS06005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EHC69_RS06010	COG0156	8-amino-7-oxononanoate synthase activity
EHC69_RS06020	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EHC69_RS06030	COG0501	Belongs to the peptidase M48B family
EHC69_RS06040	COG0300	oxidoreductase activity
EHC69_RS06055	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EHC69_RS06080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EHC69_RS06085	COG2915	High frequency lysogenization protein hflD homolog
EHC69_RS06090	COG0482	sulfurtransferase activity
EHC69_RS06100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC69_RS06110	COG1757	Na H antiporter
EHC69_RS06125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EHC69_RS06130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EHC69_RS06135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EHC69_RS06140	COG0131	Imidazoleglycerol-phosphate dehydratase
EHC69_RS06140	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EHC69_RS06145	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EHC69_RS06150	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EHC69_RS06155	COG0107	imidazoleglycerol-phosphate synthase activity
EHC69_RS06160	COG0140	phosphoribosyl-ATP diphosphatase activity
EHC69_RS06160	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EHC69_RS06165	COG3012	SEC-C Motif Domain Protein
EHC69_RS06175	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EHC69_RS06180	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC69_RS06185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHC69_RS06190	COG0215	cysteine-tRNA ligase activity
EHC69_RS06195	COG1435	thymidine kinase activity
EHC69_RS06200	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EHC69_RS06225	COG2116	formate transmembrane transporter activity
EHC69_RS06235	COG0390	transport system, permease component
EHC69_RS06240	COG4459	periplasmic nitrate reductase
EHC69_RS06245	COG3005	denitrification pathway
EHC69_RS06250	COG0243	molybdopterin cofactor binding
EHC69_RS06265	COG1227	inorganic diphosphatase activity
EHC69_RS06275	COG4172	Belongs to the ABC transporter superfamily
EHC69_RS06285	COG4171	peptide transport system, permease
EHC69_RS06290	COG4168	peptide transport system, permease
EHC69_RS06300	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EHC69_RS06305	COG1842	Phage shock protein A
EHC69_RS06315	COG1983	PspC domain protein
EHC69_RS06320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC69_RS06335	COG2818	Glycosylase
EHC69_RS06340	COG5380	lipid catabolic process
EHC69_RS06345	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EHC69_RS06350	COG0626	cystathionine gamma-synthase activity
EHC69_RS06360	COG0733	neurotransmitter:sodium symporter activity
EHC69_RS06370	COG0564	pseudouridine synthase activity
EHC69_RS06380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC69_RS06385	COG1151	hydroxylamine reductase activity
EHC69_RS06390	COG3604	Transcriptional regulator
EHC69_RS06405	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHC69_RS06410	COG4136	ATPase activity
EHC69_RS06415	COG4135	transport system, permease component
EHC69_RS06420	COG4134	Bacterial extracellular solute-binding protein
EHC69_RS06425	COG0398	Pfam SNARE associated Golgi protein
EHC69_RS06435	COG0493	'glutamate synthase
EHC69_RS06460	COG3313	Fe-S protein
EHC69_RS06490	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EHC69_RS06495	COG2205	protein histidine kinase activity
EHC69_RS06500	COG0745	RESPONSE REGULATOR receiver
EHC69_RS06510	COG1061	Type III restriction enzyme res subunit
EHC69_RS06515	COG1187	pseudouridine synthase activity
EHC69_RS06520	COG2814	Major facilitator Superfamily
EHC69_RS06550	COG3005	denitrification pathway
EHC69_RS06555	COG0702	epimerase
EHC69_RS06560	COG0534	Mate efflux family protein
EHC69_RS06565	COG4181	ATPase activity
EHC69_RS06580	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC69_RS06600	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EHC69_RS06605	COG2985	domain, Protein
EHC69_RS06605	COG3273	potassium ion transport
EHC69_RS06610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EHC69_RS06625	COG1737	Transcriptional regulator
EHC69_RS06630	COG0076	glutamate decarboxylase activity
EHC69_RS06640	COG2431	L-lysine efflux transmembrane transporter activity
EHC69_RS06655	COG3070	regulator of competence-specific genes
EHC69_RS06670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC69_RS06670	COG4191	Histidine kinase
EHC69_RS06680	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EHC69_RS06685	COG3048	D-serine ammonia-lyase activity
EHC69_RS06690	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EHC69_RS06695	COG4988	ABC transporter
EHC69_RS06700	COG0492	ferredoxin-NADP+ reductase activity
EHC69_RS06720	COG0745	RESPONSE REGULATOR receiver
EHC69_RS06720	COG3706	GGDEF domain
EHC69_RS06725	COG0471	metal ion transport
EHC69_RS06730	COG2949	membrane
EHC69_RS06735	COG0281	malic enzyme
EHC69_RS06740	COG1643	Atp-dependent helicase
EHC69_RS06745	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EHC69_RS06760	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EHC69_RS06795	COG0277	FAD linked oxidase domain protein
EHC69_RS06795	COG0247	lactate metabolic process
EHC69_RS06810	COG2986	histidine ammonia-lyase
EHC69_RS06815	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EHC69_RS06820	COG0010	Belongs to the arginase family
EHC69_RS06825	COG1228	amidohydrolase
EHC69_RS06830	COG2188	Transcriptional regulator
EHC69_RS06845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHC69_RS06855	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EHC69_RS06865	COG0393	Putative heavy-metal-binding
EHC69_RS06895	COG3706	GGDEF domain
EHC69_RS06900	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EHC69_RS06905	COG0072	phenylalanine-tRNA ligase activity
EHC69_RS06905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC69_RS06920	COG0776	regulation of translation
EHC69_RS06930	COG0500	methyltransferase
EHC69_RS06935	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EHC69_RS06940	COG0295	cytidine deaminase activity
EHC69_RS06945	COG1346	cytolysis
EHC69_RS06950	COG1380	Effector of murein hydrolase LrgA
EHC69_RS06955	COG2925	Exonuclease
EHC69_RS06970	COG0702	epimerase
EHC69_RS06975	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EHC69_RS06980	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EHC69_RS06990	COG2062	phosphohistidine phosphatase, SixA
EHC69_RS07005	COG2988	succinylglutamate desuccinylase activity
EHC69_RS07010	COG4139	cobalamin transport
EHC69_RS07015	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
EHC69_RS07035	COG0583	DNA-binding transcription factor activity
EHC69_RS07055	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EHC69_RS07060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EHC69_RS07065	COG3475	LICD family
EHC69_RS07070	COG1451	nucleotide metabolic process
EHC69_RS07075	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EHC69_RS07105	COG3938	Belongs to the proline racemase family
EHC69_RS07125	COG2423	ornithine cyclodeaminase activity
EHC69_RS07130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHC69_RS07135	COG3842	ATPase activity
EHC69_RS07140	COG1176	ABC-type spermidine putrescine transport system, permease component I
EHC69_RS07145	COG1177	transmembrane transport
EHC69_RS07155	COG3291	Pkd domain containing protein
EHC69_RS07175	COG0444	Belongs to the ABC transporter superfamily
EHC69_RS07180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC69_RS07185	COG0601	transmembrane transport
EHC69_RS07195	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC69_RS07205	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EHC69_RS07215	COG0625	glutathione transferase activity
EHC69_RS07280	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EHC69_RS07285	COG0583	DNA-binding transcription factor activity
EHC69_RS07320	COG0471	metal ion transport
EHC69_RS07325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC69_RS07325	COG4191	Histidine kinase
EHC69_RS07335	COG3300	MHYT domain
EHC69_RS07335	COG5001	Diguanylate cyclase
EHC69_RS07345	COG1280	lysine exporter protein (LysE YggA)
EHC69_RS07350	COG1328	CTP reductase activity
EHC69_RS07355	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC69_RS07365	COG0861	Integral membrane protein TerC family
EHC69_RS07375	COG0739	heme binding
EHC69_RS07415	COG3501	Rhs element vgr protein
EHC69_RS07440	COG0515	serine threonine protein kinase
EHC69_RS07475	COG1522	sequence-specific DNA binding
EHC69_RS07560	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EHC69_RS07575	COG0814	amino acid
EHC69_RS07600	COG1132	(ABC) transporter
EHC69_RS07605	COG1132	(ABC) transporter
EHC69_RS07635	COG0443	Heat shock 70 kDa protein
EHC69_RS07640	COG0443	Heat shock 70 kDa protein
EHC69_RS07650	COG3706	GGDEF domain
EHC69_RS07680	COG0243	molybdopterin cofactor binding
EHC69_RS07685	COG0437	4 iron, 4 sulfur cluster binding
EHC69_RS07690	COG3302	dmso reductase anchor subunit
EHC69_RS07705	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHC69_RS07710	COG1643	Atp-dependent helicase
EHC69_RS07725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC69_RS07735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EHC69_RS07740	COG1215	transferase activity, transferring glycosyl groups
EHC69_RS07745	COG0438	transferase activity, transferring glycosyl groups
EHC69_RS07790	COG2204	response regulator
EHC69_RS07825	COG1793	dna ligase
EHC69_RS07835	COG0534	Mate efflux family protein
EHC69_RS07840	COG0307	riboflavin synthase, alpha
EHC69_RS07855	COG2201	protein-glutamate methylesterase activity
EHC69_RS07860	COG3706	GGDEF domain
EHC69_RS07870	COG0791	NLP P60 protein
EHC69_RS07875	COG0840	transmembrane signaling receptor activity
EHC69_RS07915	COG1940	carbohydrate kinase activity
EHC69_RS07930	COG0746	molybdenum cofactor guanylyltransferase activity
EHC69_RS07935	COG3842	ATPase activity
EHC69_RS07955	COG2204	response regulator
EHC69_RS07960	COG4191	Histidine kinase
EHC69_RS07970	COG0488	(ABC) transporter
EHC69_RS07975	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHC69_RS08000	COG3381	protein complex oligomerization
EHC69_RS08010	COG3383	formate dehydrogenase (NAD+) activity
EHC69_RS08010	COG0243	molybdopterin cofactor binding
EHC69_RS08015	COG0437	4 iron, 4 sulfur cluster binding
EHC69_RS08045	COG0004	ammonium transporteR
EHC69_RS08055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EHC69_RS08060	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC69_RS08065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC69_RS08070	COG1177	transmembrane transport
EHC69_RS08075	COG1176	ABC-type spermidine putrescine transport system, permease component I
EHC69_RS08080	COG3842	ATPase activity
EHC69_RS08100	COG0037	tRNA processing
EHC69_RS08110	COG0589	response to stress
EHC69_RS08115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC69_RS08130	COG2217	Heavy metal translocating P-type atpase
EHC69_RS08140	COG2010	Cytochrome c
EHC69_RS08155	COG3278	Belongs to the heme-copper respiratory oxidase family
EHC69_RS08405	COG4128	Pfam Zonular occludens toxin
EHC69_RS08435	COG3120	sequence-specific DNA binding
EHC69_RS08440	COG1067	ATP-dependent peptidase activity
EHC69_RS08445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC69_RS08470	COG0116	Belongs to the methyltransferase superfamily
EHC69_RS08470	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EHC69_RS08485	COG0167	dihydroorotate dehydrogenase activity
EHC69_RS08490	COG2902	Dehydrogenase
EHC69_RS08500	COG0308	aminopeptidase N
EHC69_RS08630	COG4695	Portal protein
EHC69_RS08710	COG1428	Deoxynucleoside kinase
EHC69_RS08755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC69_RS08755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC69_RS08800	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EHC69_RS08805	COG0308	aminopeptidase N
EHC69_RS08820	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EHC69_RS08825	COG1956	GAF domain-containing protein
EHC69_RS08830	COG1132	(ABC) transporter
EHC69_RS08835	COG2995	paraquat-inducible protein a
EHC69_RS08840	COG3008	intermembrane lipid transfer
EHC69_RS08845	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EHC69_RS08845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHC69_RS08865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC69_RS08870	COG1666	GTP binding
EHC69_RS08885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC69_RS08890	COG4597	amino acid ABC transporter
EHC69_RS08895	COG0765	amino acid transport
EHC69_RS08900	COG1126	abc transporter atp-binding protein
EHC69_RS08905	COG0670	Belongs to the BI1 family
EHC69_RS08915	COG2920	part of a sulfur-relay system
EHC69_RS08920	COG1254	Belongs to the acylphosphatase family
EHC69_RS08925	COG0840	transmembrane signaling receptor activity
EHC69_RS08930	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EHC69_RS08970	COG3706	GGDEF domain
EHC69_RS08975	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EHC69_RS08980	COG0602	queuosine metabolic process
EHC69_RS08985	COG0561	phosphatase activity
EHC69_RS09010	COG2828	Protein conserved in bacteria
EHC69_RS09020	COG0372	Belongs to the citrate synthase family
EHC69_RS09025	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EHC69_RS09055	COG0730	response to heat
EHC69_RS09075	COG0457	Tetratricopeptide repeat
EHC69_RS09140	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC69_RS09145	COG4790	Type iii secretion
EHC69_RS09150	COG4794	Type iii secretion
EHC69_RS09155	COG4791	protein targeting
EHC69_RS09160	COG4792	protein secretion
EHC69_RS09170	COG1073	alpha beta
EHC69_RS09175	COG1073	alpha beta
EHC69_RS09185	COG0583	DNA-binding transcription factor activity
EHC69_RS09230	COG3177	Filamentation induced by cAMP protein fic
EHC69_RS09250	COG4669	(LipO)protein
EHC69_RS09320	COG1012	belongs to the aldehyde dehydrogenase family
EHC69_RS09325	COG3284	Transcriptional regulator
EHC69_RS09345	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EHC69_RS09350	COG0363	glucosamine-6-phosphate deaminase activity
EHC69_RS09355	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EHC69_RS09360	COG4565	transcriptional regulatory protein
EHC69_RS09365	COG3290	protein histidine kinase activity
EHC69_RS09380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC69_RS09395	COG1858	cytochrome C peroxidase
EHC69_RS09400	COG0527	aspartate kinase activity
EHC69_RS09405	COG0662	Cupin 2, conserved barrel domain protein
EHC69_RS09410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHC69_RS09415	COG0456	acetyltransferase
EHC69_RS09420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC69_RS09440	COG4176	ABC-type proline glycine betaine transport system permease component
EHC69_RS09445	COG2113	Glycine betaine
EHC69_RS09455	COG1022	Amp-dependent synthetase and ligase
EHC69_RS09465	COG1028	Short-chain dehydrogenase reductase Sdr
EHC69_RS09475	COG0745	RESPONSE REGULATOR receiver
EHC69_RS09480	COG0642	Histidine kinase
EHC69_RS09485	COG1368	sulfuric ester hydrolase activity
EHC69_RS09510	COG1115	amino acid carrier protein
EHC69_RS09525	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EHC69_RS09565	COG1733	regulation of RNA biosynthetic process
EHC69_RS09575	COG3550	peptidyl-serine autophosphorylation
EHC69_RS09620	COG0210	DNA helicase
EHC69_RS09670	COG4804	nuclease activity
EHC69_RS09690	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EHC69_RS09705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHC69_RS09710	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHC69_RS09765	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EHC69_RS09795	COG0531	amino acid
EHC69_RS09810	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EHC69_RS09815	COG3063	Type IV pilus biogenesis stability protein PilW
EHC69_RS09845	COG0110	maltose O-acetyltransferase activity
EHC69_RS09870	COG2315	Protein conserved in bacteria
EHC69_RS09875	COG1846	Transcriptional regulator
EHC69_RS09885	COG2207	Transcriptional regulator
EHC69_RS09890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHC69_RS09900	COG2771	luxR family
EHC69_RS09900	COG2200	EAL domain
EHC69_RS09910	COG1227	inorganic diphosphatase activity
EHC69_RS09915	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHC69_RS09920	COG1012	belongs to the aldehyde dehydrogenase family
EHC69_RS09925	COG2957	Belongs to the agmatine deiminase family
EHC69_RS09935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC69_RS09940	COG1012	belongs to the aldehyde dehydrogenase family
EHC69_RS09945	COG1396	sequence-specific DNA binding
EHC69_RS09945	COG1917	Cupin 2, conserved barrel domain protein
EHC69_RS09950	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EHC69_RS09960	COG0174	glutamine synthetase
EHC69_RS09965	COG1757	Na H antiporter
EHC69_RS10025	COG4115	mRNA cleavage
EHC69_RS10030	COG2161	toxin-antitoxin pair type II binding
EHC69_RS10140	COG0456	acetyltransferase
EHC69_RS10155	COG4628	conserved protein (DUF2132)
EHC69_RS10165	COG1280	lysine exporter protein (LysE YggA)
EHC69_RS10180	COG2314	TM2 domain
EHC69_RS10230	COG0346	lactoylglutathione lyase activity
EHC69_RS10295	COG0456	acetyltransferase
EHC69_RS10605	COG0251	oxidation-reduction process
EHC69_RS10800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC69_RS10810	COG3768	UPF0283 membrane protein
EHC69_RS10815	COG3106	COG3106 Predicted ATPase
EHC69_RS10835	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHC69_RS10840	COG0784	Response regulator, receiver
EHC69_RS10840	COG2205	protein histidine kinase activity
EHC69_RS10850	COG0494	nUDIX hydrolase
EHC69_RS10855	COG0814	amino acid
EHC69_RS10860	COG1760	l-serine dehydratase
EHC69_RS10865	COG2200	EAL domain
EHC69_RS10875	COG0720	synthase
EHC69_RS10885	COG0017	Asparaginyl-tRNA synthetase
EHC69_RS10895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC69_RS10920	COG1448	Aminotransferase
EHC69_RS10940	COG0840	transmembrane signaling receptor activity
EHC69_RS10945	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC69_RS10950	COG1846	Transcriptional regulator
EHC69_RS10975	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EHC69_RS10990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHC69_RS10995	COG3108	Peptidase M15
EHC69_RS11000	COG2989	Protein conserved in bacteria
EHC69_RS11025	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC69_RS11035	COG4235	cytochrome complex assembly
EHC69_RS11035	COG3088	subunit of a heme lyase
EHC69_RS11045	COG1138	Cytochrome C-type biogenesis protein
EHC69_RS11050	COG3301	Polysulphide reductase, NrfD
EHC69_RS11055	COG0437	4 iron, 4 sulfur cluster binding
EHC69_RS11065	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EHC69_RS11085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC69_RS11090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHC69_RS11095	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHC69_RS11120	COG0019	diaminopimelate decarboxylase activity
EHC69_RS11160	COG0322	excinuclease ABC activity
EHC69_RS11165	COG2197	response regulator
EHC69_RS11170	COG0417	DNA replication proofreading
EHC69_RS11180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHC69_RS11185	COG3099	Belongs to the UPF0263 family
EHC69_RS11195	COG1187	pseudouridine synthase activity
EHC69_RS11205	COG0009	L-threonylcarbamoyladenylate synthase
EHC69_RS11210	COG0613	PHP domain protein
EHC69_RS11220	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHC69_RS11225	COG0512	Glutamine amidotransferase of anthranilate synthase
EHC69_RS11230	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHC69_RS11235	COG0135	phosphoribosylanthranilate isomerase activity
EHC69_RS11235	COG0134	indole-3-glycerol-phosphate synthase activity
EHC69_RS11240	COG0133	tryptophan synthase activity
EHC69_RS11245	COG0159	tryptophan synthase activity
EHC69_RS11250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC69_RS11255	COG0318	PFAM AMP-dependent synthetase and ligase
EHC69_RS11265	COG1301	dicarboxylic acid transport
EHC69_RS11285	COG2917	probably involved in intracellular septation
EHC69_RS11290	COG1607	acyl-coa hydrolase
EHC69_RS11295	COG2350	Protein conserved in bacteria
EHC69_RS11305	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHC69_RS11315	COG0583	DNA-binding transcription factor activity
EHC69_RS11330	COG2203	Gaf domain
EHC69_RS11330	COG3706	GGDEF domain
EHC69_RS11330	COG4251	negative regulation of phosphorylation
EHC69_RS11330	COG5001	Diguanylate cyclase
EHC69_RS11335	COG1032	radical SAM domain protein
EHC69_RS11340	COG0840	transmembrane signaling receptor activity
EHC69_RS11350	COG0745	RESPONSE REGULATOR receiver
EHC69_RS11355	COG5002	protein histidine kinase activity
EHC69_RS11355	COG3850	Histidine kinase
EHC69_RS11390	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHC69_RS11405	COG1335	isochorismatase
EHC69_RS11410	COG0577	efflux transmembrane transporter activity
EHC69_RS11410	COG1136	(ABC) transporter
EHC69_RS11420	COG1136	(ABC) transporter
EHC69_RS11420	COG0577	efflux transmembrane transporter activity
EHC69_RS11430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC69_RS11460	COG3118	belongs to the thioredoxin family
EHC69_RS11465	COG4232	protein-disulfide reductase activity
EHC69_RS11505	COG2863	cytochrome
EHC69_RS11510	COG3258	Cytochrome c
EHC69_RS11515	COG2995	paraquat-inducible protein a
EHC69_RS11520	COG3008	intermembrane lipid transfer
EHC69_RS11520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EHC69_RS11530	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EHC69_RS11555	COG4166	transmembrane transport
EHC69_RS11560	COG0284	orotidine-5'-phosphate decarboxylase activity
EHC69_RS11565	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EHC69_RS11570	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EHC69_RS11580	COG0539	negative regulation of cytoplasmic translation
EHC69_RS11585	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EHC69_RS11590	COG0616	signal peptide processing
EHC69_RS11595	COG1028	Short-chain dehydrogenase reductase Sdr
EHC69_RS11610	COG0587	DNA-directed DNA polymerase activity
EHC69_RS11615	COG0784	Response regulator, receiver
EHC69_RS11615	COG0835	chemotaxis
EHC69_RS11620	COG1940	carbohydrate kinase activity
EHC69_RS11625	COG0469	pyruvate kinase activity
EHC69_RS11630	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC69_RS11645	COG0733	neurotransmitter:sodium symporter activity
EHC69_RS11665	COG1263	PTS System
EHC69_RS11665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC69_RS11670	COG0084	hydrolase, TatD family'
EHC69_RS11680	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EHC69_RS11685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHC69_RS11715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHC69_RS11720	COG0416	fatty acid biosynthetic process
EHC69_RS11730	COG1399	metal-binding, possibly nucleic acid-binding protein
EHC69_RS11735	COG0424	maF-like protein
EHC69_RS11740	COG0564	pseudouridine synthase activity
EHC69_RS11745	COG1530	ribonuclease E activity
EHC69_RS11750	COG0659	secondary active sulfate transmembrane transporter activity
EHC69_RS11755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHC69_RS11760	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EHC69_RS11770	COG0572	uridine kinase
EHC69_RS11775	COG0489	protein tyrosine kinase activity
EHC69_RS11780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC69_RS11780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC69_RS11790	COG2186	Transcriptional regulator
EHC69_RS11795	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC69_RS11800	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EHC69_RS11805	COG3318	Belongs to the UPF0149 family
EHC69_RS11805	COG3012	SEC-C Motif Domain Protein
EHC69_RS11810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC69_RS11815	COG0745	RESPONSE REGULATOR receiver
EHC69_RS11815	COG3706	GGDEF domain
EHC69_RS11820	COG0366	Alpha amylase catalytic
EHC69_RS11825	COG1122	ATPase activity
EHC69_RS11830	COG4120	Belongs to the binding-protein-dependent transport system permease family
EHC69_RS11840	COG3092	negative regulation of chromosome organization
EHC69_RS11845	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHC69_RS11850	COG0280	phosphate acetyltransferase
EHC69_RS11850	COG0857	belongs to the CobB CobQ family
EHC69_RS11855	COG3174	membrane
EHC69_RS11865	COG0435	Glutathione S-transferase
EHC69_RS11875	COG0444	Belongs to the ABC transporter superfamily
EHC69_RS11880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC69_RS11885	COG0601	transmembrane transport
EHC69_RS11895	COG0314	molybdopterin synthase activity
EHC69_RS11900	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EHC69_RS11905	COG0315	cyclic pyranopterin monophosphate synthase activity
EHC69_RS11910	COG0521	Mo-molybdopterin cofactor biosynthetic process
EHC69_RS11915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHC69_RS11920	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EHC69_RS11925	COG2198	Histidine kinase
EHC69_RS11930	COG2204	response regulator
EHC69_RS11935	COG0556	nucleotide-excision repair
EHC69_RS11950	COG4657	Part of a membrane complex involved in electron transport
EHC69_RS11955	COG2878	Part of a membrane complex involved in electron transport
EHC69_RS11960	COG4656	Part of a membrane complex involved in electron transport
EHC69_RS11965	COG4658	electron transport chain
EHC69_RS11970	COG4659	FMN binding
EHC69_RS11975	COG4660	Part of a membrane complex involved in electron transport
EHC69_RS11980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EHC69_RS11985	COG0346	lactoylglutathione lyase activity
EHC69_RS11995	COG2885	chlorophyll binding
EHC69_RS12010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EHC69_RS12015	COG2056	Na+-H+ antiporter family
EHC69_RS12025	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EHC69_RS12045	COG1012	belongs to the aldehyde dehydrogenase family
EHC69_RS12045	COG1454	alcohol dehydrogenase
EHC69_RS12050	COG2095	MarC family integral membrane protein
EHC69_RS12055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC69_RS12060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHC69_RS12065	COG1757	Na H antiporter
EHC69_RS12080	COG3081	Nucleoid-associated protein
EHC69_RS12085	COG3082	Protein of unknown function (DUF1414)
EHC69_RS12090	COG3083	sulfuric ester hydrolase activity
EHC69_RS12100	COG0582	viral genome integration into host DNA
EHC69_RS12130	COG0582	viral genome integration into host DNA
EHC69_RS12160	COG0123	including yeast histone deacetylase and acetoin utilization protein
EHC69_RS12180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC69_RS12185	COG0778	Nitroreductase
EHC69_RS12190	COG0446	pyridine nucleotide-disulphide oxidoreductase
EHC69_RS12190	COG1902	pentaerythritol trinitrate reductase activity
EHC69_RS12195	COG0616	signal peptide processing
EHC69_RS12200	COG0252	asparaginase activity
EHC69_RS12205	COG3139	Protein of unknown function (DUF1315)
EHC69_RS12215	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC69_RS12220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC69_RS12235	COG2226	methyltransferase
EHC69_RS12255	COG1785	Belongs to the alkaline phosphatase family
EHC69_RS12265	COG0346	lactoylglutathione lyase activity
EHC69_RS12270	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EHC69_RS12275	COG0668	transmembrane transport
EHC69_RS12280	COG2983	Belongs to the UPF0260 family
EHC69_RS12285	COG2261	transglycosylase associated protein
EHC69_RS12300	COG3681	Belongs to the UPF0597 family
EHC69_RS12305	COG0251	oxidation-reduction process
EHC69_RS12310	COG0814	amino acid
EHC69_RS12315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EHC69_RS12320	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EHC69_RS12325	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EHC69_RS12335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHC69_RS12340	COG2832	Protein of unknown function (DUF454)
EHC69_RS12350	COG0745	RESPONSE REGULATOR receiver
EHC69_RS12355	COG0583	DNA-binding transcription factor activity
EHC69_RS12360	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EHC69_RS12365	COG1286	toxin biosynthetic process
EHC69_RS12370	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EHC69_RS12375	COG0285	dihydrofolate synthase activity
EHC69_RS12380	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHC69_RS12385	COG0101	tRNA pseudouridine synthase activity
EHC69_RS12395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHC69_RS12400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC69_RS12405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EHC69_RS12410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC69_RS12410	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EHC69_RS12430	COG3101	peptidyl-lysine hydroxylation
EHC69_RS12440	COG2860	membrane
EHC69_RS12445	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EHC69_RS12450	COG2890	protein-(glutamine-N5) methyltransferase activity
EHC69_RS12455	COG2840	Smr protein MutS2
EHC69_RS12460	COG2062	phosphohistidine phosphatase, SixA
EHC69_RS12475	COG1024	Enoyl-CoA hydratase
EHC69_RS12475	COG1250	3-hydroxyacyl-CoA dehydrogenase
EHC69_RS12480	COG0183	Belongs to the thiolase family
EHC69_RS12495	COG2067	long-chain fatty acid transport protein
EHC69_RS12505	COG2853	Lipoprotein
EHC69_RS12520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EHC69_RS12525	COG1138	Cytochrome C-type biogenesis protein
EHC69_RS12530	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EHC69_RS12535	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC69_RS12540	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC69_RS12545	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC69_RS12550	COG4133	protoheme IX ABC transporter activity
EHC69_RS12560	COG0835	chemotaxis
EHC69_RS12570	COG1192	Involved in chromosome partitioning
EHC69_RS12575	COG2201	protein-glutamate methylesterase activity
EHC69_RS12580	COG0643	Histidine kinase
EHC69_RS12580	COG2198	Histidine kinase
EHC69_RS12585	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EHC69_RS12600	COG0455	bacterial-type flagellum organization
EHC69_RS12625	COG1987	bacterial-type flagellum assembly
EHC69_RS12675	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC69_RS12685	COG1677	Flagellar hook-basal body complex protein FliE
EHC69_RS12690	COG2204	response regulator
EHC69_RS12695	COG4191	Histidine kinase
EHC69_RS12705	COG1516	flagellar protein fliS
EHC69_RS12715	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHC69_RS12720	COG1334	flagellar protein FlaG
EHC69_RS12725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC69_RS12730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC69_RS12740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC69_RS12745	COG2837	iron assimilation
EHC69_RS12775	COG1393	Belongs to the ArsC family
EHC69_RS12780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC69_RS12800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHC69_RS12805	COG2716	regulation of RNA biosynthetic process
EHC69_RS12810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EHC69_RS12825	COG4783	chaperone-mediated protein folding
EHC69_RS12830	COG1393	Belongs to the ArsC family
EHC69_RS12850	COG2233	PERMEase
EHC69_RS12855	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EHC69_RS12860	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EHC69_RS12865	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EHC69_RS12870	COG0121	glutamine amidotransferase
EHC69_RS12875	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EHC69_RS12880	COG1960	acyl-CoA dehydrogenase activity
EHC69_RS12910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EHC69_RS12915	COG0328	RNA-DNA hybrid ribonuclease activity
EHC69_RS12920	COG2226	methyltransferase
EHC69_RS12925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHC69_RS12930	COG1388	LysM domain
EHC69_RS12930	COG0741	lytic transglycosylase activity
EHC69_RS12940	COG3021	interspecies interaction between organisms
EHC69_RS12945	COG0347	Belongs to the P(II) protein family
EHC69_RS12955	COG0037	tRNA processing
EHC69_RS12960	COG0825	malonyl-CoA metabolic process
EHC69_RS12965	COG0587	DNA-directed DNA polymerase activity
EHC69_RS12975	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC69_RS12980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC69_RS12985	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC69_RS12990	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EHC69_RS13000	COG0750	zinc metalloprotease
EHC69_RS13005	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EHC69_RS13010	COG0575	Belongs to the CDS family
EHC69_RS13015	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EHC69_RS13020	COG0233	cytoplasmic translational termination
EHC69_RS13025	COG0528	UMP kinase activity
EHC69_RS13030	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EHC69_RS13035	COG0052	Belongs to the universal ribosomal protein uS2 family
EHC69_RS13040	COG0024	Methionine aminopeptidase
EHC69_RS13045	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EHC69_RS13055	COG0564	pseudouridine synthase activity
EHC69_RS13060	COG3098	single-species biofilm formation
EHC69_RS13085	COG1671	Belongs to the UPF0178 family
EHC69_RS13090	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EHC69_RS13100	COG0254	rRNA binding
EHC69_RS13105	COG1720	tRNA m6t6A37 methyltransferase activity
EHC69_RS13110	COG0442	prolyl-tRNA aminoacylation
EHC69_RS13130	COG0733	neurotransmitter:sodium symporter activity
EHC69_RS13145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC69_RS13150	COG0514	ATP-dependent DNA helicase (RecQ)
EHC69_RS13155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHC69_RS13170	COG1477	protein flavinylation
EHC69_RS13175	COG2871	sodium ion transport
EHC69_RS13180	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC69_RS13185	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC69_RS13190	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC69_RS13195	COG1805	sodium ion transport
EHC69_RS13200	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC69_RS13205	COG0271	Belongs to the BolA IbaG family
EHC69_RS13210	COG2813	Specifically methylates the guanine in position
EHC69_RS13215	COG3056	Lipoprotein
EHC69_RS13235	COG1595	DNA-templated transcription, initiation
EHC69_RS13265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHC69_RS13270	COG0693	protein deglycase activity
EHC69_RS13275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EHC69_RS13280	COG3706	GGDEF domain
EHC69_RS13285	COG2166	iron-sulfur cluster assembly
EHC69_RS13290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EHC69_RS13295	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EHC69_RS13305	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EHC69_RS13305	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EHC69_RS13315	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EHC69_RS13320	COG1074	ATP-dependent DNA helicase activity
EHC69_RS13325	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EHC69_RS13345	COG3141	response to X-ray
EHC69_RS13350	COG2171	N-acyltransferase activity
EHC69_RS13355	COG0584	glycerophosphoryl diester phosphodiesterase
EHC69_RS13360	COG2271	Major facilitator Superfamily
EHC69_RS13375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EHC69_RS13380	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EHC69_RS13385	COG1349	DNA-binding transcription factor activity
EHC69_RS13390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EHC69_RS13395	COG0598	Magnesium transport protein CorA
EHC69_RS13410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC69_RS13415	COG1609	Transcriptional regulator
EHC69_RS13420	COG2211	Major facilitator Superfamily
EHC69_RS13435	COG2017	converts alpha-aldose to the beta-anomer
EHC69_RS13440	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EHC69_RS13450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EHC69_RS13460	COG1609	Transcriptional regulator
EHC69_RS13465	COG3250	beta-galactosidase activity
EHC69_RS13470	COG2731	YhcH YjgK YiaL family protein
EHC69_RS13475	COG0531	amino acid
EHC69_RS13480	COG0583	DNA-binding transcription factor activity
EHC69_RS13540	COG4964	Belongs to the GSP D family
EHC69_RS13565	COG2169	Transcriptional regulator
EHC69_RS13570	COG1022	Amp-dependent synthetase and ligase
EHC69_RS13580	COG0583	DNA-binding transcription factor activity
EHC69_RS13585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC69_RS13590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EHC69_RS13600	COG0560	Phosphoserine phosphatase
EHC69_RS13610	COG0813	purine-nucleoside phosphorylase activity
EHC69_RS13615	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EHC69_RS13620	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EHC69_RS13625	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EHC69_RS13630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC69_RS13635	COG0084	hydrolase, TatD family'
EHC69_RS13645	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EHC69_RS13665	COG3153	acetyltransferase
EHC69_RS13690	COG0534	Mate efflux family protein
EHC69_RS13705	COG1185	polyribonucleotide nucleotidyltransferase activity
EHC69_RS13710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EHC69_RS13715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EHC69_RS13720	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EHC69_RS13725	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EHC69_RS13730	COG0195	Participates in both transcription termination and antitermination
EHC69_RS13735	COG0779	Required for maturation of 30S ribosomal subunits
EHC69_RS13750	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EHC69_RS13760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC69_RS13765	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EHC69_RS13770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHC69_RS13775	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EHC69_RS13780	COG1534	Rna-binding protein
EHC69_RS13785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC69_RS13790	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EHC69_RS13795	COG2027	D-alanyl-D-alanine carboxypeptidase
EHC69_RS13805	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHC69_RS13810	COG0739	heme binding
EHC69_RS13815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC69_RS13820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC69_RS13825	COG0316	Belongs to the HesB IscA family
EHC69_RS13830	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EHC69_RS13835	COG0628	permease
EHC69_RS13840	COG2813	Specifically methylates the guanine in position
EHC69_RS13845	COG2198	Histidine kinase
EHC69_RS13845	COG2205	protein histidine kinase activity
EHC69_RS13845	COG0784	Response regulator, receiver
EHC69_RS13845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC69_RS13850	COG0747	negative chemotaxis
EHC69_RS13860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC69_RS13865	COG0444	Belongs to the ABC transporter superfamily
EHC69_RS13870	COG4608	Belongs to the ABC transporter superfamily
EHC69_RS13880	COG2971	BadF BadG BcrA BcrD
EHC69_RS13895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC69_RS13900	COG3842	ATPase activity
EHC69_RS13910	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC69_RS13915	COG0004	ammonium transporteR
EHC69_RS13925	COG3112	Uncharacterised protein family (UPF0231)
EHC69_RS13930	COG1049	propionate catabolic process, 2-methylcitrate cycle
EHC69_RS13935	COG1752	Esterase of the alpha-beta hydrolase superfamily
EHC69_RS13940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EHC69_RS13945	COG1643	Atp-dependent helicase
EHC69_RS13950	COG1489	DNA binding
EHC69_RS13955	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EHC69_RS13965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC69_RS13980	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHC69_RS13985	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EHC69_RS13990	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EHC69_RS13995	COG1560	Kdo2-lipid A biosynthetic process
EHC69_RS14000	COG0842	Transport permease protein
EHC69_RS14005	COG1131	(ABC) transporter
EHC69_RS14015	COG0659	secondary active sulfate transmembrane transporter activity
EHC69_RS14020	COG0288	reversible hydration of carbon dioxide
EHC69_RS14035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC69_RS14040	COG0508	dehydrogenase complex catalyzes the overall conversion of
EHC69_RS14045	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EHC69_RS14050	COG2186	Transcriptional regulator
EHC69_RS14060	COG0157	Belongs to the NadC ModD family
EHC69_RS14070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC69_RS14075	COG1459	type II secretion system
EHC69_RS14085	COG0237	dephospho-CoA kinase activity
EHC69_RS14090	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EHC69_RS14095	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EHC69_RS14100	COG0335	large ribosomal subunit rRNA binding
EHC69_RS14105	COG0336	Belongs to the RNA methyltransferase TrmD family
EHC69_RS14110	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EHC69_RS14115	COG0228	four-way junction DNA binding
EHC69_RS14120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EHC69_RS14125	COG4137	Cytochrome C assembly protein
EHC69_RS14130	COG4536	flavin adenine dinucleotide binding
EHC69_RS14135	COG1854	S-ribosylhomocysteine lyase activity
EHC69_RS14145	COG2918	glutathione biosynthetic process
EHC69_RS14150	COG0612	Peptidase, M16
EHC69_RS14155	COG1238	metal cluster binding
EHC69_RS14160	COG1063	alcohol dehydrogenase
EHC69_RS14165	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EHC69_RS14170	COG0511	ligase activity, forming carbon-carbon bonds
EHC69_RS14170	COG5016	pyruvate
EHC69_RS14175	COG3630	sodium ion export across plasma membrane
EHC69_RS14235	COG0527	aspartate kinase activity
EHC69_RS14240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHC69_RS14245	COG2137	regulation of response to DNA damage stimulus
EHC69_RS14250	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EHC69_RS14255	COG1546	Belongs to the CinA family
EHC69_RS14260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EHC69_RS14275	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EHC69_RS14280	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EHC69_RS14285	COG0585	pseudouridine synthase activity
EHC69_RS14290	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EHC69_RS14295	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EHC69_RS14300	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EHC69_RS14305	COG0148	phosphopyruvate hydratase activity
EHC69_RS14310	COG0504	CTP synthase activity
EHC69_RS14315	COG3956	TIGRFAM MazG family protein
EHC69_RS14320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHC69_RS14330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHC69_RS14340	COG0736	holo-[acyl-carrier-protein] synthase activity
EHC69_RS14345	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EHC69_RS14350	COG1381	Involved in DNA repair and RecF pathway recombination
EHC69_RS14355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EHC69_RS14360	COG0571	ribonuclease III activity
EHC69_RS14365	COG0681	Belongs to the peptidase S26 family
EHC69_RS14370	COG0481	GTPase activity
EHC69_RS14375	COG3086	response to oxidative stress
EHC69_RS14385	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EHC69_RS14390	COG1595	DNA-templated transcription, initiation
EHC69_RS14400	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EHC69_RS14410	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EHC69_RS14415	COG0354	folic acid binding
EHC69_RS14430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC69_RS14435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC69_RS14440	COG3079	Belongs to the UPF0149 family
EHC69_RS14450	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EHC69_RS14460	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EHC69_RS14465	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EHC69_RS14470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC69_RS14480	COG0583	DNA-binding transcription factor activity
EHC69_RS14490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EHC69_RS14495	COG0668	transmembrane transport
EHC69_RS14500	COG0191	fructose-bisphosphate aldolase activity
EHC69_RS14505	COG0126	phosphoglycerate kinase activity
EHC69_RS14510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC69_RS14515	COG4771	TonB-dependent receptor
EHC69_RS14520	COG0583	DNA-binding transcription factor activity
EHC69_RS14525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHC69_RS14535	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHC69_RS14545	COG3091	SprT-like family
EHC69_RS14550	COG2356	endonuclease I
EHC69_RS14555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EHC69_RS14560	COG0189	ligase activity
EHC69_RS14565	COG1678	Uncharacterized ACR, COG1678
EHC69_RS14570	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EHC69_RS14585	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EHC69_RS14590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHC69_RS14595	COG0762	integral membrane protein
EHC69_RS14600	COG1872	DUF167
EHC69_RS14610	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EHC69_RS14615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHC69_RS14620	COG2066	Belongs to the glutaminase family
EHC69_RS14630	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EHC69_RS14640	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EHC69_RS14645	COG0741	lytic transglycosylase activity
EHC69_RS14685	COG0840	transmembrane signaling receptor activity
EHC69_RS14715	COG1012	belongs to the aldehyde dehydrogenase family
EHC69_RS14765	COG3437	response regulator, receiver
EHC69_RS14775	COG3394	polysaccharide catabolic process
EHC69_RS14780	COG1486	melibiose metabolic process
EHC69_RS14785	COG1447	Phosphotransferase system cellobiose-specific component IIA
EHC69_RS14790	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EHC69_RS14795	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EHC69_RS14800	COG0726	polysaccharide deacetylase
EHC69_RS14850	COG4974	Belongs to the 'phage' integrase family
EHC69_RS14860	COG1028	Short-chain dehydrogenase reductase Sdr
EHC69_RS14865	COG4325	translation initiation factor activity
EHC69_RS14875	COG0795	lipopolysaccharide-transporting ATPase activity
EHC69_RS14880	COG0795	lipopolysaccharide-transporting ATPase activity
EHC69_RS14885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHC69_RS14890	COG2927	DNA polymerase III (CHI subunit)
EHC69_RS14895	COG0525	valine-tRNA ligase activity
EHC69_RS14925	COG2235	arginine
EHC69_RS14930	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EHC69_RS14940	COG0540	Belongs to the ATCase OTCase family
EHC69_RS14945	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EHC69_RS14950	COG0251	oxidation-reduction process
EHC69_RS14955	COG0204	Acyl-transferase
EHC69_RS14960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHC69_RS14965	COG5007	Belongs to the BolA IbaG family
EHC69_RS14975	COG2854	intermembrane phospholipid transfer
EHC69_RS14980	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EHC69_RS14985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EHC69_RS14990	COG1127	ABC transporter
EHC69_RS15000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EHC69_RS15000	COG0517	IMP dehydrogenase activity
EHC69_RS15010	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EHC69_RS15015	COG1137	ATPase activity
EHC69_RS15025	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHC69_RS15030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC69_RS15035	COG1660	Displays ATPase and GTPase activities
EHC69_RS15040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC69_RS15045	COG2239	Acts as a magnesium transporter
EHC69_RS15050	COG0312	modulator of DNA gyrase
EHC69_RS15055	COG3028	Belongs to the UPF0307 family
EHC69_RS15060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHC69_RS15065	COG0564	pseudouridine synthase activity
EHC69_RS15080	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EHC69_RS15085	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EHC69_RS15090	COG0312	modulator of DNA gyrase
EHC69_RS15095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHC69_RS15100	COG3164	Protein of unknown function
EHC69_RS15105	COG1530	ribonuclease E activity
EHC69_RS15110	COG0424	maF-like protein
EHC69_RS15115	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EHC69_RS15120	COG1792	Involved in formation and maintenance of cell shape
EHC69_RS15125	COG1077	Cell shape determining protein MreB Mrl
EHC69_RS15170	COG1459	type II secretion system
EHC69_RS15175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC69_RS15185	COG3409	Peptidoglycan-binding domain 1 protein
EHC69_RS15185	COG3267	Type II secretory pathway component ExeA
EHC69_RS15210	COG2199	diguanylate cyclase activity
EHC69_RS15210	COG2200	EAL domain
EHC69_RS15215	COG0629	single-stranded DNA binding
EHC69_RS15230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EHC69_RS15240	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EHC69_RS15245	COG0527	aspartate kinase activity
EHC69_RS15250	COG0646	methionine synthase
EHC69_RS15250	COG1410	methionine synthase
EHC69_RS15325	COG0175	sulfate reduction
EHC69_RS15330	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC69_RS15335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EHC69_RS15360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC69_RS15370	COG0735	belongs to the Fur family
EHC69_RS15380	COG0166	Belongs to the GPI family
EHC69_RS15385	COG0432	Pfam Uncharacterised protein family UPF0047
EHC69_RS15395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC69_RS15400	COG0305	Participates in initiation and elongation during chromosome replication
EHC69_RS15410	COG0359	binds to the 23S rRNA
EHC69_RS15420	COG2965	DNA replication, synthesis of RNA primer
EHC69_RS15425	COG0360	Binds together with S18 to 16S ribosomal RNA
EHC69_RS15430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EHC69_RS15435	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EHC69_RS15445	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EHC69_RS15450	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EHC69_RS15480	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EHC69_RS15490	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EHC69_RS15490	COG0678	peroxiredoxin activity
EHC69_RS15505	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EHC69_RS15505	COG0165	Argininosuccinate lyase
EHC69_RS15510	COG0137	argininosuccinate synthase activity
EHC69_RS15515	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EHC69_RS15520	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EHC69_RS15525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC69_RS15530	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EHC69_RS15540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EHC69_RS15545	COG0460	homoserine dehydrogenase
EHC69_RS15545	COG0527	aspartate kinase activity
EHC69_RS15550	COG0626	cystathionine gamma-synthase activity
EHC69_RS15560	COG0281	malic enzyme
EHC69_RS15570	COG2906	2 iron, 2 sulfur cluster binding
EHC69_RS15575	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHC69_RS15580	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC69_RS15585	COG0049	tRNA binding
EHC69_RS15600	COG2923	Belongs to the DsrF TusC family
EHC69_RS15605	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EHC69_RS15610	COG2964	Protein conserved in bacteria
EHC69_RS15615	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC69_RS15625	COG2900	Belongs to the SlyX family
EHC69_RS15630	COG1446	asparaginase
EHC69_RS15640	COG1047	Peptidyl-prolyl cis-trans
EHC69_RS15655	COG2249	NAD(P)H dehydrogenase (quinone) activity
EHC69_RS15665	COG0488	(ABC) transporter
EHC69_RS15675	COG0429	hydrolase of the alpha beta-hydrolase fold
EHC69_RS15680	COG3089	Belongs to the UPF0270 family
EHC69_RS15685	COG3954	Phosphoribulokinase
EHC69_RS15690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC69_RS15700	COG1012	belongs to the aldehyde dehydrogenase family
EHC69_RS15710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EHC69_RS15715	COG0512	Glutamine amidotransferase of anthranilate synthase
EHC69_RS15745	COG0180	Tryptophanyl-tRNA synthetase
EHC69_RS15750	COG0546	phosphoglycolate phosphatase activity
EHC69_RS15755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC69_RS15760	COG0557	exoribonuclease II activity
EHC69_RS15765	COG1959	2 iron, 2 sulfur cluster binding
EHC69_RS15770	COG1017	nitric oxide dioxygenase activity
EHC69_RS15770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC69_RS15775	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EHC69_RS15785	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EHC69_RS15790	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EHC69_RS15795	COG0330	HflC and HflK could
EHC69_RS15800	COG0330	HflC and HflK could
EHC69_RS15805	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EHC69_RS15815	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EHC69_RS15820	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EHC69_RS15825	COG0860	N-Acetylmuramoyl-L-alanine amidase
EHC69_RS15830	COG0802	atpase or kinase
EHC69_RS15835	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EHC69_RS15905	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EHC69_RS15910	COG1162	GTPase activity
EHC69_RS15915	COG0688	phosphatidylethanolamine metabolic process
EHC69_RS15920	COG0471	metal ion transport
EHC69_RS15935	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EHC69_RS15940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC69_RS15945	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EHC69_RS15950	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EHC69_RS15955	COG1045	serine acetyltransferase
EHC69_RS15960	COG4942	peptidase
EHC69_RS15980	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EHC69_RS15990	COG1053	succinate dehydrogenase
EHC69_RS15995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EHC69_RS16000	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EHC69_RS16005	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EHC69_RS16015	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHC69_RS16020	COG1509	lysine 2,3-aminomutase activity
EHC69_RS16035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC69_RS16050	COG0459	protein refolding
EHC69_RS16055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHC69_RS16060	COG0534	Mate efflux family protein
EHC69_RS16065	COG0205	6-phosphofructokinase activity
EHC69_RS16075	COG3678	ATP-independent chaperone mediated protein folding
EHC69_RS16080	COG0745	RESPONSE REGULATOR receiver
EHC69_RS16085	COG2205	protein histidine kinase activity
EHC69_RS16095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EHC69_RS16100	COG3030	protein affecting phage T7 exclusion by the F plasmid
EHC69_RS16105	COG1027	Aspartate ammonia-lyase
EHC69_RS16110	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EHC69_RS16115	COG4232	protein-disulfide reductase activity
EHC69_RS16125	COG3263	regulation of cellular component size
EHC69_RS16135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC69_RS16160	COG0784	Response regulator, receiver
EHC69_RS16160	COG2205	protein histidine kinase activity
EHC69_RS16165	COG2814	Major facilitator Superfamily
EHC69_RS16180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC69_RS16185	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EHC69_RS16190	COG0511	ligase activity, forming carbon-carbon bonds
EHC69_RS16195	COG0439	Biotin carboxylase
EHC69_RS16205	COG2264	protein methyltransferase activity
EHC69_RS16210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC69_RS16215	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EHC69_RS16220	COG2814	Major facilitator Superfamily
EHC69_RS16225	COG0488	(ABC) transporter
EHC69_RS16230	COG3706	GGDEF domain
EHC69_RS16310	COG1982	Orn Lys Arg decarboxylase major
EHC69_RS16315	COG0531	amino acid
EHC69_RS16325	COG3710	Transcriptional regulator
EHC69_RS16330	COG0789	Transcriptional regulator
EHC69_RS16340	COG0138	bifunctional purine biosynthesis protein purh
EHC69_RS16350	COG0151	Belongs to the GarS family
EHC69_RS16365	COG1253	flavin adenine dinucleotide binding
EHC69_RS16370	COG3068	Protein conserved in bacteria
EHC69_RS16375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC69_RS16380	COG1573	uracil-dna glycosylase
EHC69_RS16385	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EHC69_RS16400	COG2816	NAD+ diphosphatase activity
EHC69_RS16405	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EHC69_RS16410	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHC69_RS16415	COG0085	RNA polymerase activity
EHC69_RS16420	COG0222	ribosome binding
EHC69_RS16425	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EHC69_RS16430	COG0081	regulation of translation
EHC69_RS16435	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EHC69_RS16440	COG0250	Participates in transcription elongation, termination and antitermination
EHC69_RS16445	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EHC69_RS16455	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHC69_RS16490	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EHC69_RS16500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHC69_RS16530	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EHC69_RS16540	COG4206	TonB-dependent receptor
EHC69_RS16560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC69_RS16565	COG0534	Mate efflux family protein
EHC69_RS16570	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EHC69_RS16575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHC69_RS16585	COG2937	Belongs to the GPAT DAPAT family
EHC69_RS16590	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EHC69_RS16595	COG3161	chorismate lyase activity
EHC69_RS16600	COG1580	Controls the rotational direction of flagella during chemotaxis
EHC69_RS16605	COG0705	Rhomboid family
EHC69_RS16610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC69_RS16620	COG2177	Part of the ABC transporter FtsEX involved in
EHC69_RS16625	COG2884	Cell division ATP-binding protein ftsE
EHC69_RS16630	COG0552	protein localization to endoplasmic reticulum
EHC69_RS16635	COG0742	ribosomal rna small subunit methyltransferase
EHC69_RS16645	COG2095	MarC family integral membrane protein
EHC69_RS16700	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC69_RS16705	COG0640	Transcriptional regulator
EHC69_RS16710	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EHC69_RS16715	COG1280	lysine exporter protein (LysE YggA)
EHC69_RS16720	COG2267	carboxylic ester hydrolase activity
EHC69_RS16725	COG0561	phosphatase activity
EHC69_RS16745	COG2200	EAL domain
EHC69_RS16745	COG2199	diguanylate cyclase activity
EHC69_RS16745	COG3287	FIST C domain
EHC69_RS16750	COG1011	Hydrolase
EHC69_RS16755	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EHC69_RS16765	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EHC69_RS16770	COG0019	diaminopimelate decarboxylase activity
EHC69_RS16780	COG1965	Belongs to the frataxin family
EHC69_RS16785	COG3072	Adenylate cyclase
EHC69_RS16790	COG0181	hydroxymethylbilane synthase activity
EHC69_RS16795	COG1587	Uroporphyrinogen-III synthase
EHC69_RS16800	COG2959	enzyme of heme biosynthesis
EHC69_RS16805	COG3071	HemY protein
EHC69_RS16815	COG3335	DDE superfamily endonuclease
EHC69_RS16860	COG0633	Ferredoxin
EHC69_RS16865	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EHC69_RS16880	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EHC69_RS16885	COG3118	belongs to the thioredoxin family
EHC69_RS16890	COG0513	Belongs to the DEAD box helicase family
EHC69_RS16895	COG0248	Ppx GppA phosphatase
EHC69_RS16900	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EHC69_RS16915	COG0514	ATP-dependent DNA helicase (RecQ)
EHC69_RS16920	COG2962	Rard protein
EHC69_RS16930	COG1280	lysine exporter protein (LysE YggA)
EHC69_RS16935	COG0405	Gamma-glutamyltransferase
EHC69_RS16945	COG0210	DNA helicase
EHC69_RS16955	COG3220	belongs to the UPF0276 family
EHC69_RS16985	COG0006	proline dipeptidase activity
EHC69_RS16985	COG0006	proline dipeptidase activity
EHC69_RS16995	COG2022	thiamine diphosphate biosynthetic process
EHC69_RS17000	COG2104	thiamine diphosphate biosynthetic process
EHC69_RS17005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EHC69_RS17015	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EHC69_RS17020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHC69_RS17035	COG3335	DDE superfamily endonuclease
EHC69_RS17080	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EHC69_RS17090	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHC69_RS17095	COG0408	coproporphyrinogen oxidase activity
EHC69_RS17100	COG0009	L-threonylcarbamoyladenylate synthase
EHC69_RS17105	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EHC69_RS17110	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EHC69_RS17115	COG0551	DNA topoisomerase type I activity
EHC69_RS17120	COG2922	Belongs to the Smg family
EHC69_RS17125	COG0758	DNA mediated transformation
EHC69_RS17135	COG0242	peptide deformylase activity
EHC69_RS17140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EHC69_RS17145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHC69_RS17145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHC69_RS17150	COG0569	domain protein
EHC69_RS17155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC69_RS17165	COG1272	protein, Hemolysin III
EHC69_RS17170	COG4326	sporulation control protein
EHC69_RS17180	COG3084	Protein conserved in bacteria
EHC69_RS17190	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EHC69_RS17195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC69_RS17200	COG0204	Acyl-transferase
EHC69_RS17280	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EHC69_RS17285	COG0606	chelatase, subunit chli
EHC69_RS17295	COG3978	acetolactate synthase activity
EHC69_RS17300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EHC69_RS17305	COG0129	dihydroxy-acid dehydratase activity
EHC69_RS17315	COG0583	DNA-binding transcription factor activity
EHC69_RS17320	COG2814	Major facilitator Superfamily
EHC69_RS17325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC69_RS17330	COG0765	amino acid transport
EHC69_RS17335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EHC69_RS17340	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EHC69_RS17345	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EHC69_RS17350	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EHC69_RS17355	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EHC69_RS17360	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHC69_RS17375	COG0356	it plays a direct role in the translocation of protons across the membrane
EHC69_RS17380	COG3312	ion transport
EHC69_RS17385	COG1475	DNA binding
EHC69_RS17390	COG1192	Involved in chromosome partitioning
EHC69_RS17395	COG0357	Ribosomal RNA small subunit methyltransferase G
EHC69_RS17400	COG0445	tRNA wobble uridine modification
EHC69_RS17405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EHC69_RS17410	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EHC69_RS17415	COG0706	membrane insertase activity
EHC69_RS17420	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EHC69_RS17425	COG0594	ribonuclease P activity
EHC69_RS17435	COG1126	abc transporter atp-binding protein
EHC69_RS17495	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHC69_RS17505	COG5001	Diguanylate cyclase
EHC69_RS17510	COG0513	Belongs to the DEAD box helicase family
EHC69_RS17515	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EHC69_RS17530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EHC69_RS17550	COG0641	radical SAM
EHC69_RS17575	COG0840	transmembrane signaling receptor activity
EHC69_RS17580	COG1119	ATPase activity
EHC69_RS17585	COG2200	EAL domain
EHC69_RS17605	COG0513	Belongs to the DEAD box helicase family
EHC69_RS17610	COG0523	cobalamin synthesis protein
EHC69_RS17620	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EHC69_RS17630	COG0133	tryptophan synthase activity
EHC69_RS17635	COG4628	conserved protein (DUF2132)
EHC69_RS17640	COG0513	Belongs to the DEAD box helicase family
EHC69_RS17645	COG3530	Putative quorum-sensing-regulated virulence factor
EHC69_RS17670	COG2154	pterin-4-alpha-carbinolamine dehydratase
EHC69_RS17675	COG3186	Phenylalanine-4-hydroxylase
EHC69_RS17680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC69_RS17685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC69_RS17725	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EHC69_RS17730	COG1454	alcohol dehydrogenase
EHC69_RS17735	COG2133	pyrroloquinoline quinone binding
EHC69_RS17745	COG0783	Belongs to the Dps family
EHC69_RS17750	COG0840	transmembrane signaling receptor activity
EHC69_RS17760	COG0577	efflux transmembrane transporter activity
EHC69_RS17760	COG1136	(ABC) transporter
EHC69_RS17780	COG2199	diguanylate cyclase activity
EHC69_RS17795	COG3036	rescue of stalled ribosome
EHC69_RS17800	COG1278	Cold shock
EHC69_RS17835	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC69_RS17840	COG0109	protoheme IX farnesyltransferase activity
EHC69_RS17845	COG1612	heme a metabolic process
EHC69_RS17870	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EHC69_RS17875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHC69_RS17880	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EHC69_RS17885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC69_RS17895	COG1280	lysine exporter protein (LysE YggA)
EHC69_RS17900	COG2207	Transcriptional regulator
EHC69_RS17930	COG0697	spore germination
EHC69_RS17955	COG2814	Major facilitator Superfamily
EHC69_RS17960	COG0583	DNA-binding transcription factor activity
EHC69_RS17970	COG0739	heme binding
EHC69_RS18010	COG0814	amino acid
EHC69_RS18030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHC69_RS18035	COG1072	(Pantothenic acid kinase))
EHC69_RS18045	COG1063	alcohol dehydrogenase
EHC69_RS18050	COG2213	PTS system mannitol-specific
EHC69_RS18055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC69_RS18075	COG0798	PFAM Bile acid sodium symporter
EHC69_RS18085	COG1881	PFAM PEBP family protein
EHC69_RS18095	COG2706	6-phosphogluconolactonase activity
EHC69_RS18100	COG0840	transmembrane signaling receptor activity
EHC69_RS18110	COG1131	(ABC) transporter
EHC69_RS18115	COG0842	Transport permease protein
EHC69_RS18130	COG3383	formate dehydrogenase (NAD+) activity
EHC69_RS18155	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC69_RS18175	COG2203	Gaf domain
EHC69_RS18175	COG2199	diguanylate cyclase activity
EHC69_RS18185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC69_RS18195	COG2067	long-chain fatty acid transport protein
EHC69_RS18205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC69_RS18220	COG0488	(ABC) transporter
EHC69_RS18225	COG0589	response to stress
EHC69_RS18230	COG2249	NAD(P)H dehydrogenase (quinone) activity
EHC69_RS18250	COG0366	Alpha amylase catalytic
EHC69_RS18260	COG4934	collagen metabolic process
EHC69_RS18275	COG0583	DNA-binding transcription factor activity
EHC69_RS18285	COG0783	Belongs to the Dps family
EHC69_RS18290	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EHC69_RS18315	COG2169	Transcriptional regulator
EHC69_RS18320	COG1486	melibiose metabolic process
EHC69_RS18325	COG2211	Major facilitator Superfamily
EHC69_RS18345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC69_RS18355	COG0835	chemotaxis
EHC69_RS18355	COG0784	Response regulator, receiver
EHC69_RS18365	COG0748	coenzyme F420 binding
EHC69_RS18370	COG3721	Heme iron utilization protein
EHC69_RS18380	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EHC69_RS18385	COG0811	peptide transport
EHC69_RS18390	COG0848	biopolymer transport protein
EHC69_RS18400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC69_RS18405	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EHC69_RS18445	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EHC69_RS18450	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EHC69_RS18455	COG0633	Ferredoxin
EHC69_RS18455	COG3217	Mosc domain protein beta barrel domain protein
EHC69_RS18455	COG0633	Ferredoxin
EHC69_RS18455	COG3217	Mosc domain protein beta barrel domain protein
EHC69_RS18465	COG0401	homolog of Blt101
EHC69_RS18475	COG0418	dihydroorotase activity
EHC69_RS18480	COG2354	Protein conserved in bacteria
EHC69_RS18510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHC69_RS18510	COG2207	Transcriptional regulator
EHC69_RS18515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC69_RS18560	COG0513	Belongs to the DEAD box helicase family
EHC69_RS18570	COG0583	DNA-binding transcription factor activity
EHC69_RS18585	COG1902	pentaerythritol trinitrate reductase activity
EHC69_RS18590	COG1063	alcohol dehydrogenase
EHC69_RS18600	COG1028	Short-chain dehydrogenase reductase Sdr
EHC69_RS18615	COG3122	Protein conserved in bacteria
EHC69_RS18630	COG0583	DNA-binding transcription factor activity
EHC69_RS18640	COG0252	asparaginase activity
EHC69_RS18645	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EHC69_RS18650	COG0574	Belongs to the PEP-utilizing enzyme family
EHC69_RS18650	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHC69_RS18670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHC69_RS18675	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC69_RS18690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC69_RS18710	COG3706	GGDEF domain
EHC69_RS18730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC69_RS18760	COG3842	ATPase activity
EHC69_RS18860	COG0583	DNA-binding transcription factor activity
EHC69_RS18870	COG4948	Mandelate Racemase Muconate Lactonizing
EHC69_RS18880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC69_RS18905	COG1342	Belongs to the UPF0251 family
EHC69_RS18915	COG3015	lipoprotein NlpE involved in copper resistance
EHC69_RS18925	COG3713	MltA-interacting MipA family protein
EHC69_RS18940	COG0583	DNA-binding transcription factor activity
EHC69_RS18970	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EHC69_RS18980	COG1335	isochorismatase
EHC69_RS18990	COG0753	catalase activity
EHC69_RS19000	COG1349	DNA-binding transcription factor activity
EHC69_RS19005	COG0346	lactoylglutathione lyase activity
EHC69_RS19010	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC69_RS19010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC69_RS19020	COG0583	DNA-binding transcription factor activity
EHC69_RS19030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC69_RS19035	COG3537	Alpha-1,2-mannosidase
EHC69_RS19040	COG3537	Alpha-1,2-mannosidase
EHC69_RS19050	COG3537	Alpha-1,2-mannosidase
EHC69_RS19055	COG3537	Alpha-1,2-mannosidase
EHC69_RS19065	COG0737	Belongs to the 5'-nucleotidase family
EHC69_RS19075	COG1309	transcriptional regulator
EHC69_RS19095	COG1280	lysine exporter protein (LysE YggA)
EHC69_RS19110	COG0459	protein refolding
EHC69_RS19115	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHC69_RS19125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC69_RS19155	COG1304	FMN binding
EHC69_RS19175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC69_RS19180	COG4786	Flagellar basal body rod
EHC69_RS19180	COG1256	bacterial-type flagellum assembly
EHC69_RS19190	COG1706	bacterial-type flagellum-dependent cell motility
EHC69_RS19195	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EHC69_RS19200	COG4786	Flagellar basal body rod
EHC69_RS19205	COG4787	bacterial-type flagellum-dependent cell motility
EHC69_RS19210	COG1749	Flagellar hook protein flgE
EHC69_RS19215	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EHC69_RS19220	COG1558	bacterial-type flagellum-dependent cell motility
EHC69_RS19225	COG1815	bacterial-type flagellum-dependent cell motility
EHC69_RS19245	COG0741	lytic transglycosylase activity
EHC69_RS19255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHC69_RS19275	COG1760	l-serine dehydratase
EHC69_RS19300	COG0583	DNA-binding transcription factor activity
EHC69_RS19315	COG2866	Carboxypeptidase
EHC69_RS19320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC69_RS19330	COG2990	Protein conserved in bacteria
EHC69_RS19355	COG3842	ATPase activity
EHC69_RS19365	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC69_RS19370	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EHC69_RS19380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC69_RS19385	COG1609	Transcriptional regulator
EHC69_RS19415	COG3240	lipase activity
EHC69_RS19425	COG0577	efflux transmembrane transporter activity
EHC69_RS19425	COG1136	(ABC) transporter
EHC69_RS19430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC69_RS19435	COG2067	long-chain fatty acid transport protein
EHC69_RS19445	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EHC69_RS19460	COG1011	Hydrolase
EHC69_RS19500	COG0110	maltose O-acetyltransferase activity
EHC69_RS19505	COG1765	OsmC-like protein
EHC69_RS19510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC69_RS19510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC69_RS19525	COG3046	protein related to deoxyribodipyrimidine photolyase
EHC69_RS19530	COG0415	Belongs to the DNA photolyase family
EHC69_RS19535	COG3706	GGDEF domain
EHC69_RS19550	COG0840	transmembrane signaling receptor activity
EHC69_RS19555	COG3706	GGDEF domain
EHC69_RS19560	COG3145	DNA-N1-methyladenine dioxygenase activity
EHC69_RS19570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC69_RS19590	COG3033	Beta-eliminating lyase
EHC69_RS19600	COG0579	oxidoreductase
EHC69_RS19630	COG3706	GGDEF domain
EHC69_RS19675	COG0583	DNA-binding transcription factor activity
EHC69_RS19680	COG0189	ligase activity
EHC69_RS19685	COG0189	ligase activity
EHC69_RS19685	COG4067	protein conserved in archaea
EHC69_RS19695	COG1166	arginine decarboxylase activity
EHC69_RS19700	COG0010	Belongs to the arginase family
EHC69_RS19705	COG2814	Major facilitator Superfamily
EHC69_RS19710	COG1770	oligopeptidase
EHC69_RS19725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EHC69_RS19730	COG1121	(ABC) transporter
EHC69_RS19735	COG0803	Belongs to the bacterial solute-binding protein 9 family
EHC69_RS19775	COG0848	biopolymer transport protein
EHC69_RS19780	COG0811	peptide transport
EHC69_RS19785	COG0811	peptide transport
EHC69_RS19805	COG0745	RESPONSE REGULATOR receiver
EHC69_RS19820	COG0584	glycerophosphoryl diester phosphodiesterase
EHC69_RS19830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHC69_RS19890	COG1901	pseudouridine methyltransferase
EHC69_RS19895	COG0312	modulator of DNA gyrase
EHC69_RS19900	COG0312	modulator of DNA gyrase
EHC69_RS19910	COG0351	phosphomethylpyrimidine kinase
EHC69_RS19915	COG1116	anion transmembrane transporter activity
EHC69_RS19920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHC69_RS19925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHC69_RS19930	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EHC69_RS19935	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EHC69_RS19940	COG0352	thiamine-phosphate diphosphorylase activity
EHC69_RS19950	COG0243	molybdopterin cofactor binding
EHC69_RS19965	COG1028	Short-chain dehydrogenase reductase Sdr
EHC69_RS19980	COG0456	acetyltransferase
EHC69_RS20000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC69_RS20005	COG1929	Belongs to the glycerate kinase type-1 family
EHC69_RS20010	COG2610	gluconate transmembrane transporter activity
EHC69_RS20015	COG3835	regulator
EHC69_RS20040	COG0546	phosphoglycolate phosphatase activity
EHC69_RS20055	COG0583	DNA-binding transcription factor activity
EHC69_RS20065	COG0583	DNA-binding transcription factor activity
EHC69_RS20075	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EHC69_RS20080	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EHC69_RS20080	COG3408	Glycogen debranching enzyme
EHC69_RS20110	COG3047	cAMP biosynthetic process
EHC69_RS20115	COG1357	PFAM Pentapeptide repeats (8 copies)
EHC69_RS20150	COG0823	Involved in the tonB-independent uptake of proteins
EHC69_RS20155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC69_RS20175	COG0800	Aldolase
EHC69_RS20180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC69_RS20195	COG1917	Cupin 2, conserved barrel domain protein
EHC69_RS20205	COG1028	Short-chain dehydrogenase reductase Sdr
EHC69_RS20225	COG0583	DNA-binding transcription factor activity
EHC69_RS20230	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EHC69_RS20235	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EHC69_RS20250	COG2199	diguanylate cyclase activity
EHC69_RS20260	COG0561	phosphatase activity
EHC69_RS20265	COG0583	DNA-binding transcription factor activity
EHC69_RS20280	COG0564	pseudouridine synthase activity
EHC69_RS20295	COG5001	Diguanylate cyclase
EHC69_RS20305	COG3123	guanosine phosphorylase activity
EHC69_RS20345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHC69_RS20355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHC69_RS20360	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EHC69_RS20375	COG2259	Doxx family
EHC69_RS20380	COG1741	Belongs to the pirin family
EHC69_RS20400	COG0363	glucosamine-6-phosphate deaminase activity
EHC69_RS20415	COG0786	glutamate:sodium symporter activity
EHC69_RS20420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC69_RS20425	COG1131	(ABC) transporter
EHC69_RS20435	COG0786	glutamate:sodium symporter activity
EHC69_RS20470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHC69_RS20480	COG3279	Response regulator of the LytR AlgR family
EHC69_RS20485	COG3275	phosphorelay sensor kinase activity
EHC69_RS20505	COG1136	(ABC) transporter
EHC69_RS20520	COG0772	Belongs to the SEDS family
EHC69_RS20525	COG0217	transcriptional regulatory protein
EHC69_RS20550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC69_RS20550	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
EHC69_RS20560	COG0444	Belongs to the ABC transporter superfamily
EHC69_RS20565	COG4608	Belongs to the ABC transporter superfamily
EHC69_RS20590	COG1444	tRNA N-acetyltransferase activity
EHC69_RS20610	COG3340	Belongs to the peptidase S51 family
EHC69_RS20615	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EHC69_RS20620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC69_RS20620	COG1263	PTS System
EHC69_RS20625	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHC69_RS20645	COG4166	transmembrane transport
EHC69_RS20690	COG0259	pyridoxamine-phosphate oxidase activity
EHC69_RS20720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC69_RS20765	COG1132	(ABC) transporter
EHC69_RS20775	COG2207	Transcriptional regulator
EHC69_RS20800	COG0800	Aldolase
EHC69_RS20805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC69_RS20810	COG1904	glucuronate isomerase
EHC69_RS20815	COG0246	Mannitol dehydrogenase
EHC69_RS20825	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EHC69_RS20835	COG2186	Transcriptional regulator
EHC69_RS20845	COG0513	Belongs to the DEAD box helicase family
EHC69_RS20850	COG2258	MOSC domain
EHC69_RS20865	COG1486	melibiose metabolic process
EHC69_RS20870	COG0583	DNA-binding transcription factor activity
EHC69_RS20875	COG0840	transmembrane signaling receptor activity
EHC69_RS20890	COG1595	DNA-templated transcription, initiation
EHC69_RS20920	COG3634	alkyl hydroperoxide reductase activity
EHC69_RS20925	COG0450	alkyl hydroperoxide reductase
EHC69_RS20930	COG1846	Transcriptional regulator
EHC69_RS20935	COG1764	response to oxidative stress
EHC69_RS20960	COG2160	L-arabinose isomerase activity
EHC69_RS20970	COG1069	ribulokinase activity
EHC69_RS20975	COG1879	ABC-type sugar transport system periplasmic component
EHC69_RS20980	COG1129	ABC transporter
EHC69_RS20985	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHC69_RS21010	COG0745	RESPONSE REGULATOR receiver
EHC69_RS21020	COG1653	transport
EHC69_RS21025	COG0019	diaminopimelate decarboxylase activity
EHC69_RS21030	COG4264	IucA IucC family
EHC69_RS21055	COG4772	TonB-dependent receptor
EHC69_RS21060	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EHC69_RS21065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC69_RS21070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC69_RS21075	COG1120	ATPase activity
EHC69_RS21080	COG0840	transmembrane signaling receptor activity
EHC69_RS21085	COG0612	Peptidase, M16
EHC69_RS21095	COG0739	heme binding
EHC69_RS21105	COG2814	Major facilitator Superfamily
EHC69_RS21145	COG2356	endonuclease I
EHC69_RS21165	COG1982	Orn Lys Arg decarboxylase major
EHC69_RS21170	COG0531	amino acid
EHC69_RS21180	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EHC69_RS21190	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EHC69_RS21195	COG1162	GTPase activity
EHC69_RS21200	COG1263	PTS System
EHC69_RS21200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC69_RS21210	COG1999	signal sequence binding
EHC69_RS21225	COG2909	trisaccharide binding
EHC69_RS21240	COG0058	SHG alpha-glucan phosphorylase activity
EHC69_RS21245	COG1640	4-alpha-glucanotransferase
EHC69_RS21250	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EHC69_RS21255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EHC69_RS21260	COG0366	Alpha amylase catalytic
EHC69_RS21275	COG3366	ferrous iron transmembrane transporter activity
EHC69_RS21280	COG0700	Nucleoside recognition
EHC69_RS21285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC69_RS21290	COG3339	Conserved Protein
EHC69_RS21295	COG1301	dicarboxylic acid transport
EHC69_RS21305	COG0583	DNA-binding transcription factor activity
EHC69_RS21320	COG3206	protein involved in exopolysaccharide biosynthesis
EHC69_RS21320	COG0489	protein tyrosine kinase activity
EHC69_RS21340	COG2095	MarC family integral membrane protein
EHC69_RS21345	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC69_RS21350	COG3397	chitin binding
EHC69_RS21370	COG1686	Belongs to the peptidase S11 family
EHC69_RS21395	COG0583	DNA-binding transcription factor activity
EHC69_RS21400	COG4628	conserved protein (DUF2132)
EHC69_RS21410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC69_RS21420	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC69_RS21425	COG0628	permease
EHC69_RS21470	COG2814	Major facilitator Superfamily
EHC69_RS21485	COG0454	-acetyltransferase
EHC69_RS21495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHC69_RS21500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC69_RS21535	COG1360	Flagellar Motor Protein
EHC69_RS21540	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EHC69_RS21545	COG1191	sigma factor activity
EHC69_RS21550	COG1580	Controls the rotational direction of flagella during chemotaxis
EHC69_RS21565	COG1516	flagellar protein fliS
EHC69_RS21570	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHC69_RS21585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC69_RS21600	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHC69_RS21610	COG1987	bacterial-type flagellum assembly
EHC69_RS21635	COG2204	response regulator
EHC69_RS21650	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC69_RS21690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHC69_RS21710	COG0346	lactoylglutathione lyase activity
EHC69_RS21745	COG0745	RESPONSE REGULATOR receiver
EHC69_RS21765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC69_RS21775	COG0156	8-amino-7-oxononanoate synthase activity
EHC69_RS21780	COG1063	alcohol dehydrogenase
EHC69_RS21820	COG0668	transmembrane transport
EHC69_RS21830	COG1304	FMN binding
EHC69_RS21835	COG1620	l-lactate permease
EHC69_RS21840	COG0583	DNA-binding transcription factor activity
EHC69_RS21845	COG1505	serine-type exopeptidase activity
EHC69_RS21850	COG4172	Belongs to the ABC transporter superfamily
EHC69_RS21860	COG1067	ATP-dependent peptidase activity
EHC69_RS21890	COG1247	-acetyltransferase
EHC69_RS21895	COG0437	4 iron, 4 sulfur cluster binding
EHC69_RS21900	COG0348	domain, Protein
EHC69_RS21915	COG1122	ATPase activity
EHC69_RS21920	COG4720	Psort location CytoplasmicMembrane, score
EHC69_RS21925	COG1566	PFAM secretion protein HlyD family protein
EHC69_RS21935	COG3706	GGDEF domain
EHC69_RS21950	COG0813	purine-nucleoside phosphorylase activity
EHC69_RS21960	COG3272	Protein of unknown function (DUF1722)
EHC69_RS21965	COG0789	Transcriptional regulator
EHC69_RS21970	COG0415	Belongs to the DNA photolyase family
EHC69_RS21975	COG1376	ErfK ybiS ycfS ynhG family protein
EHC69_RS21975	COG1388	LysM domain
EHC69_RS21985	COG0513	Belongs to the DEAD box helicase family
EHC69_RS21990	COG1770	oligopeptidase
EHC69_RS21995	COG4771	TonB-dependent receptor
EHC69_RS22020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EHC69_RS22025	COG0573	inorganic phosphate transmembrane transporter activity
EHC69_RS22030	COG0581	inorganic phosphate transmembrane transporter activity
EHC69_RS22035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EHC69_RS22050	COG2304	oxidoreductase activity
EHC69_RS22070	COG0714	Associated with various cellular activities
EHC69_RS22080	COG0840	transmembrane signaling receptor activity
EHC69_RS22090	COG2197	response regulator
EHC69_RS22125	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EHC69_RS22125	COG2885	chlorophyll binding
EHC69_RS22140	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EHC69_RS22145	COG1120	ATPase activity
EHC69_RS22150	COG4774	siderophore transport
EHC69_RS22155	COG1132	(ABC) transporter
EHC69_RS22160	COG5002	protein histidine kinase activity
EHC69_RS22170	COG0569	domain protein
EHC69_RS22175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC69_RS22185	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EHC69_RS22190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC69_RS22205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC69_RS22205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC69_RS22205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC69_RS22210	COG2207	Transcriptional regulator
EHC69_RS22220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC69_RS22225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC69_RS22230	COG2084	Dehydrogenase
EHC69_RS22235	COG0753	catalase activity
EHC69_RS22245	COG2130	NADP-dependent
EHC69_RS22250	COG1309	transcriptional regulator
EHC69_RS22315	COG3842	ATPase activity
EHC69_RS22325	COG1175	transmembrane transport
EHC69_RS22330	COG3833	ABC-type maltose transport systems, permease component
EHC69_RS22350	COG3746	phosphate-selective porin O and P
EHC69_RS22370	COG1028	Short-chain dehydrogenase reductase Sdr
EHC69_RS22390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EHC69_RS22400	COG0625	glutathione transferase activity
EHC69_RS22410	COG1686	Belongs to the peptidase S11 family
EHC69_RS22435	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHC69_RS22450	COG1278	Cold shock
EHC69_RS22455	COG1741	Belongs to the pirin family
EHC69_RS22460	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC69_RS22470	COG1846	Transcriptional regulator
EHC69_RS22495	COG0673	inositol 2-dehydrogenase activity
EHC69_RS22500	COG2194	sulfuric ester hydrolase activity
EHC69_RS22505	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EHC69_RS22515	COG2205	protein histidine kinase activity
EHC69_RS22520	COG0745	RESPONSE REGULATOR receiver
EHC69_RS22525	COG4221	oxidoreductase activity
EHC69_RS22545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC69_RS22565	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC69_RS22575	COG2814	Major facilitator Superfamily
EHC69_RS22590	COG1418	mRNA catabolic process
EHC69_RS22600	COG0402	S-adenosylhomocysteine deaminase activity
EHC69_RS22605	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EHC69_RS22615	COG2239	Acts as a magnesium transporter
EHC69_RS22620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EHC69_RS22635	COG0531	amino acid
EHC69_RS22645	COG1522	sequence-specific DNA binding
EHC69_RS22650	COG0583	DNA-binding transcription factor activity
EHC69_RS22670	COG0784	Response regulator, receiver
EHC69_RS22670	COG2205	protein histidine kinase activity
EHC69_RS22670	COG5002	protein histidine kinase activity
EHC69_RS22675	COG0673	inositol 2-dehydrogenase activity
EHC69_RS22680	COG0534	Mate efflux family protein
EHC69_RS22685	COG2926	Belongs to the UPF0265 family
EHC69_RS22700	COG3132	Protein of unknown function, DUF480
EHC69_RS22705	COG2827	Endonuclease containing a URI domain
EHC69_RS22710	COG1879	ABC-type sugar transport system periplasmic component
EHC69_RS22715	COG2205	protein histidine kinase activity
EHC69_RS22715	COG0784	Response regulator, receiver
EHC69_RS22725	COG1566	PFAM secretion protein HlyD family protein
EHC69_RS22745	COG1522	sequence-specific DNA binding
EHC69_RS22770	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC69_RS22775	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC69_RS22785	COG1280	lysine exporter protein (LysE YggA)
EHC69_RS22795	COG0183	Belongs to the thiolase family
EHC69_RS22815	COG3005	denitrification pathway
EHC69_RS22825	COG0243	molybdopterin cofactor binding
EHC69_RS22840	COG3850	Histidine kinase
EHC69_RS22845	COG2197	response regulator
EHC69_RS22860	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC69_RS22880	COG0840	transmembrane signaling receptor activity
EHC69_RS22890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC69_RS22900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC69_RS22905	COG2814	Major facilitator Superfamily
EHC69_RS22915	COG0840	transmembrane signaling receptor activity
EHC69_RS22920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHC69_RS22925	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHC69_RS22950	COG2897	thiosulfate sulfurtransferase activity
EHC69_RS22970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EHC69_RS22980	COG0302	gtp cyclohydrolase
EHC69_RS22985	COG1914	H( )-stimulated, divalent metal cation uptake system
EHC69_RS22995	COG0038	chloride channel
EHC69_RS23010	COG4989	oxidoreductase activity
EHC69_RS23025	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EHC69_RS23025	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EHC69_RS23030	COG0516	GMP reductase activity
EHC69_RS23040	COG2204	response regulator
EHC69_RS23085	COG0515	serine threonine protein kinase
EHC69_RS23110	COG1196	nuclear chromosome segregation
EHC69_RS23120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC69_RS23190	COG3474	cytochrome
EHC69_RS23200	COG0789	Transcriptional regulator
EHC69_RS23205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EHC69_RS23210	COG0384	phenazine biosynthesis protein PhzF
EHC69_RS23225	COG1271	oxidase subunit
EHC69_RS23230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC69_RS23235	COG0110	maltose O-acetyltransferase activity
EHC69_RS23245	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EHC69_RS23245	COG3264	Mechanosensitive ion channel
EHC69_RS23260	COG2205	protein histidine kinase activity
EHC69_RS23260	COG3437	response regulator, receiver
EHC69_RS23260	COG4999	Histidine kinase
EHC69_RS23260	COG3850	Histidine kinase
EHC69_RS23270	COG0439	Biotin carboxylase
EHC69_RS23285	COG1960	acyl-CoA dehydrogenase activity
EHC69_RS23295	COG0183	Belongs to the thiolase family
EHC69_RS23305	COG1960	acyl-CoA dehydrogenase activity
EHC69_RS23310	COG1024	Enoyl-CoA hydratase
EHC69_RS23325	COG1028	Short-chain dehydrogenase reductase Sdr
EHC69_RS23335	COG3706	GGDEF domain
EHC69_RS23340	COG1309	transcriptional regulator
EHC69_RS23345	COG1012	belongs to the aldehyde dehydrogenase family
EHC69_RS23365	COG4175	Glycine betaine
EHC69_RS23365	COG0517	IMP dehydrogenase activity
EHC69_RS23380	COG0330	HflC and HflK could
EHC69_RS23390	COG3300	MHYT domain
EHC69_RS23390	COG5001	Diguanylate cyclase
EHC69_RS23410	COG0784	Response regulator, receiver
EHC69_RS23410	COG2205	protein histidine kinase activity
EHC69_RS23470	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHC69_RS23475	COG5001	Diguanylate cyclase
EHC69_RS23480	COG1869	D-ribose catabolic process
EHC69_RS23485	COG1129	ABC transporter
EHC69_RS23490	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHC69_RS23495	COG1879	ABC-type sugar transport system periplasmic component
EHC69_RS23500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC69_RS23505	COG1609	Transcriptional regulator
EHC69_RS23520	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EHC69_RS23540	COG0745	RESPONSE REGULATOR receiver
EHC69_RS23555	COG1785	Belongs to the alkaline phosphatase family
EHC69_RS23575	COG3706	GGDEF domain
EHC69_RS23575	COG0745	RESPONSE REGULATOR receiver
EHC69_RS23585	COG0814	amino acid
EHC69_RS23590	COG0456	acetyltransferase
EHC69_RS23595	COG0243	molybdopterin cofactor binding
EHC69_RS23615	COG3707	response regulator
EHC69_RS23625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHC69_RS23630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHC69_RS23635	COG1116	anion transmembrane transporter activity
EHC69_RS23640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC69_RS23640	COG2146	nitrite reductase [NAD(P)H] activity
EHC69_RS23695	COG0515	serine threonine protein kinase
EHC69_RS23695	COG2815	serine threonine protein kinase
EHC69_RS23730	COG0631	protein serine/threonine phosphatase activity
EHC69_RS23785	COG3501	Rhs element vgr protein
EHC69_RS23800	COG0420	3'-5' exonuclease activity
EHC69_RS23805	COG0419	ATPase involved in DNA repair
EHC69_RS23825	COG3040	lipid binding
EHC69_RS23835	COG2814	Major facilitator Superfamily
EHC69_RS23845	COG1288	antiporter activity
EHC69_RS23860	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EHC69_RS23875	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EHC69_RS23895	COG0583	DNA-binding transcription factor activity
EHC69_RS23900	COG0277	FAD linked oxidase domain protein
EHC69_RS23920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC69_RS23970	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC69_RS23970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC69_RS24015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC69_RS24020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC69_RS24025	COG2146	nitrite reductase [NAD(P)H] activity
EHC69_RS24030	COG2116	formate transmembrane transporter activity
EHC69_RS24050	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EHC69_RS24080	COG0534	Mate efflux family protein
EHC69_RS24090	COG2814	Major facilitator Superfamily
EHC69_RS24095	COG3118	belongs to the thioredoxin family
EHC69_RS24100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHC69_RS24125	COG2271	Major facilitator Superfamily
EHC69_RS24130	COG3851	Histidine kinase
EHC69_RS24135	COG2197	response regulator
EHC69_RS24145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHC69_RS24150	COG0583	DNA-binding transcription factor activity
EHC69_RS24160	COG0243	molybdopterin cofactor binding
EHC69_RS24190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC69_RS24205	COG1328	CTP reductase activity
EHC69_RS24210	COG0602	queuosine metabolic process
EHC69_RS24215	COG0534	Mate efflux family protein
EHC69_RS24235	COG4067	protein conserved in archaea
EHC69_RS24235	COG0189	ligase activity
EHC69_RS24245	COG3111	PFAM Bacterial OB fold (BOF) protein
EHC69_RS24250	COG1492	cobalamin metabolic process
EHC69_RS24255	COG0725	ABC transporter, periplasmic molybdate-binding protein
EHC69_RS24260	COG4149	molybdate abc transporter
EHC69_RS24265	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EHC69_RS24275	COG4251	negative regulation of phosphorylation
EHC69_RS24275	COG2203	Gaf domain
EHC69_RS24275	COG5001	Diguanylate cyclase
EHC69_RS24275	COG3706	GGDEF domain
EHC69_RS24285	COG0745	RESPONSE REGULATOR receiver
EHC69_RS24285	COG3706	GGDEF domain
EHC69_RS24300	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EHC69_RS24305	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EHC69_RS24330	COG3140	Belongs to the UPF0181 family
EHC69_RS24335	COG0589	response to stress
EHC69_RS24345	COG0583	DNA-binding transcription factor activity
EHC69_RS24430	COG0023	Translation Initiation Factor
EHC69_RS24440	COG1181	Belongs to the D-alanine--D-alanine ligase family
EHC69_RS24450	COG0045	succinate-CoA ligase (ADP-forming) activity
EHC69_RS24450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC69_RS24450	COG1042	CoA-binding domain protein
EHC69_RS24455	COG0583	DNA-binding transcription factor activity
EHC69_RS24460	COG1629	transport
EHC69_RS24460	COG4771	TonB-dependent receptor
EHC69_RS24470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EHC69_RS24480	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EHC69_RS24485	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EHC69_RS24490	COG1984	allophanate hydrolase subunit 2
EHC69_RS24500	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EHC69_RS24505	COG4181	ATPase activity
EHC69_RS24515	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EHC69_RS24520	COG3300	MHYT domain
EHC69_RS24520	COG5001	Diguanylate cyclase
EHC69_RS24530	COG0484	heat shock protein binding
EHC69_RS24555	COG4533	DNA binding
EHC69_RS24565	COG2050	protein possibly involved in aromatic compounds catabolism
EHC69_RS24580	COG2067	long-chain fatty acid transport protein
EHC69_RS24585	COG2267	carboxylic ester hydrolase activity
EHC69_RS24600	COG0861	Integral membrane protein TerC family
EHC69_RS24605	COG0737	Belongs to the 5'-nucleotidase family
EHC69_RS24610	COG3593	DNA synthesis involved in DNA repair
EHC69_RS24620	COG0583	DNA-binding transcription factor activity
EHC69_RS24625	COG2116	formate transmembrane transporter activity
EHC69_RS24630	COG2353	YceI-like domain
EHC69_RS24635	COG3038	cytochrome b561
EHC69_RS24655	COG0513	Belongs to the DEAD box helicase family
EHC69_RS24660	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
EHC69_RS24675	COG0546	phosphoglycolate phosphatase activity
EHC69_RS24685	COG3437	response regulator, receiver
EHC69_RS24685	COG0784	Response regulator, receiver
EHC69_RS24730	COG3550	peptidyl-serine autophosphorylation
EHC69_RS24745	COG2188	Transcriptional regulator
EHC69_RS24750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC69_RS24755	COG0531	amino acid
EHC69_RS24785	COG2188	Transcriptional regulator
EHC69_RS24870	COG2181	nitrate reductase activity
EHC69_RS24875	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EHC69_RS24880	COG1140	nitrate reductase beta subunit
EHC69_RS24885	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHC69_RS24890	COG2223	nitrite transmembrane transporter activity
EHC69_RS24895	COG3850	Histidine kinase
EHC69_RS24900	COG2197	response regulator
EHC69_RS24905	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EHC69_RS24950	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EHC69_RS24980	COG4558	Periplasmic binding protein
EHC69_RS25000	COG0348	domain, Protein
EHC69_RS25060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC69_RS25065	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EHC69_RS25070	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC69_RS25085	COG2207	Transcriptional regulator
EHC69_RS25090	COG1979	alcohol dehydrogenase
EHC69_RS25110	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC69_RS25115	COG2271	Major facilitator Superfamily
EHC69_RS25120	COG0469	pyruvate kinase activity
EHC69_RS25125	COG1126	abc transporter atp-binding protein
EHC69_RS25130	COG0765	amino acid transport
EHC69_RS25135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC69_RS25140	COG0765	amino acid transport
EHC69_RS25145	COG2199	diguanylate cyclase activity
EHC69_RS25145	COG2200	EAL domain
EHC69_RS25145	COG2203	Gaf domain
EHC69_RS25165	COG1609	Transcriptional regulator
EHC69_RS25170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC69_RS25170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC69_RS25175	COG1105	Belongs to the carbohydrate kinase PfkB family
EHC69_RS25180	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EHC69_RS25180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC69_RS25180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC69_RS25220	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHC69_RS25225	COG0509	glycine decarboxylation via glycine cleavage system
EHC69_RS25230	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHC69_RS25230	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHC69_RS25255	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EHC69_RS25260	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHC69_RS25265	COG0583	DNA-binding transcription factor activity
EHC69_RS25270	COG2176	DNA-directed DNA polymerase activity
EHC69_RS25315	COG0242	peptide deformylase activity
EHC69_RS25345	COG2239	Acts as a magnesium transporter
EHC69_RS25365	COG0346	lactoylglutathione lyase activity
EHC69_RS25370	COG1902	pentaerythritol trinitrate reductase activity
EHC69_RS25395	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EHC69_RS25405	COG0069	glutamate synthase activity
EHC69_RS25405	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EHC69_RS25415	COG4565	transcriptional regulatory protein
EHC69_RS25420	COG3290	protein histidine kinase activity
EHC69_RS25455	COG2076	Multidrug Resistance protein
EHC69_RS25470	COG0671	phosphoesterase, PA-phosphatase related
EHC69_RS25485	COG2962	Rard protein
EHC69_RS25505	COG0784	Response regulator, receiver
EHC69_RS25505	COG0835	chemotaxis
EHC69_RS25530	COG2197	response regulator
EHC69_RS25540	COG3706	GGDEF domain
EHC69_RS25545	COG2197	response regulator
EHC69_RS25550	COG3300	MHYT domain
EHC69_RS25550	COG5001	Diguanylate cyclase
EHC69_RS25565	COG0583	DNA-binding transcription factor activity
EHC69_RS25570	COG0583	DNA-binding transcription factor activity
EHC69_RS25630	COG4964	Belongs to the GSP D family
EHC69_RS25655	COG2207	Transcriptional regulator
EHC69_RS25675	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EHC69_RS25695	COG1214	PFAM Peptidase M22, glycoprotease
EHC69_RS25695	COG0456	acetyltransferase
EHC69_RS25705	COG3069	C4-dicarboxylate transmembrane transporter activity
EHC69_RS25710	COG1704	LemA family
EHC69_RS25715	COG0501	Belongs to the peptidase M48B family
EHC69_RS25745	COG0641	radical SAM
EHC69_RS25765	COG3111	PFAM Bacterial OB fold (BOF) protein
EHC69_RS25770	COG1597	lipid kinase activity
EHC69_RS25775	COG0583	DNA-binding transcription factor activity
EHC69_RS25780	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC69_RS25810	COG0714	Associated with various cellular activities
EHC69_RS25815	COG0641	radical SAM
EHC69_RS25820	COG3119	arylsulfatase activity
EHC69_RS25835	COG3119	arylsulfatase activity
EHC69_RS25840	COG3119	arylsulfatase activity
EHC69_RS25845	COG0745	RESPONSE REGULATOR receiver
EHC69_RS25860	COG0784	Response regulator, receiver
EHC69_RS25860	COG2198	Histidine kinase
EHC69_RS25860	COG2205	protein histidine kinase activity
EHC69_RS25865	COG1879	ABC-type sugar transport system periplasmic component
EHC69_RS25870	COG1803	Methylglyoxal synthase
EHC69_RS25875	COG0210	DNA helicase
EHC69_RS25880	COG1289	transmembrane transporter activity
EHC69_RS25915	COG4771	TonB-dependent receptor
EHC69_RS25915	COG1629	transport
EHC69_RS25930	COG0789	Transcriptional regulator
EHC69_RS25935	COG4604	ABC transporter, ATP-binding protein
EHC69_RS25940	COG4605	iron ion homeostasis
EHC69_RS25945	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC69_RS25950	COG4607	ABC-type enterochelin transport system periplasmic component
EHC69_RS25975	COG2847	Copper chaperone PCu(A)C
EHC69_RS25980	COG0443	Heat shock 70 kDa protein
EHC69_RS26015	COG0625	glutathione transferase activity
EHC69_RS26030	COG4160	amino acid transport
EHC69_RS26035	COG4215	(ABC) transporter
EHC69_RS26040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC69_RS26045	COG1126	abc transporter atp-binding protein
EHC69_RS26085	COG1902	pentaerythritol trinitrate reductase activity
EHC69_RS26100	COG0109	protoheme IX farnesyltransferase activity
EHC69_RS26105	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EHC69_RS26110	COG1845	cytochrome c oxidase, subunit III
EHC69_RS26115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHC69_RS26120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EHC69_RS26125	COG1028	Short-chain dehydrogenase reductase Sdr
EHC69_RS26135	COG1024	Enoyl-CoA hydratase
EHC69_RS26140	COG1024	Enoyl-CoA hydratase
EHC69_RS26155	COG0183	Belongs to the thiolase family
EHC69_RS26165	COG1960	acyl-CoA dehydrogenase activity
EHC69_RS26170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EHC69_RS26175	COG1024	Enoyl-CoA hydratase
EHC69_RS26185	COG5413	integral membrane protein
EHC69_RS26230	COG1733	regulation of RNA biosynthetic process
EHC69_RS26240	COG1902	pentaerythritol trinitrate reductase activity
EHC69_RS26245	COG1902	pentaerythritol trinitrate reductase activity
EHC69_RS26265	COG0583	DNA-binding transcription factor activity
EHC69_RS26270	COG2814	Major facilitator Superfamily
EHC69_RS26280	COG3550	peptidyl-serine autophosphorylation
EHC69_RS26285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EHC69_RS26345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EHC69_RS26350	COG0840	transmembrane signaling receptor activity
EHC69_RS26355	COG4580	involved in the transport of maltose and maltodextrins
EHC69_RS26360	COG1874	Beta-galactosidase
EHC69_RS26370	COG3833	ABC-type maltose transport systems, permease component
EHC69_RS26375	COG1175	transmembrane transport
EHC69_RS26380	COG2182	Extracellular solute-binding protein
EHC69_RS26405	COG3328	transposase activity
EHC69_RS26595	COG0739	heme binding
EHC69_RS26610	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EHC69_RS26630	COG4932	domain protein
EHC69_RS26630	COG5492	domain, Protein
EHC69_RS26650	COG4974	Belongs to the 'phage' integrase family
EHC69_RS26660	COG2337	Toxic component of a toxin-antitoxin (TA) module
EHC69_RS26715	COG2885	chlorophyll binding
EHC69_RS26755	COG4932	domain protein
EHC69_RS26755	COG5492	domain, Protein
EHC69_RS26790	COG1192	Involved in chromosome partitioning
EHC69_RS26825	COG5268	conjugation
EHC69_RS26830	COG3451	type IV secretory pathway VirB4
EHC69_RS26840	COG4962	Type ii secretion system protein e
EHC69_RS26860	COG3504	Conjugal transfer protein
EHC69_RS26870	COG2948	multi-organism process
EHC69_RS26895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC69_RS26970	COG2801	Transposase and inactivated derivatives
EHC69_RS26995	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC69_RS27020	COG1196	nuclear chromosome segregation
EHC69_RS27125	COG3209	COG3209 Rhs family protein
EHC69_RS27135	COG3209	COG3209 Rhs family protein
EHC69_RS27275	COG3423	Transcriptional regulator
EHC69_RS27410	COG3316	Transposase and inactivated derivatives
EHC69_RS27415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EHC69_RS27455	COG3316	Transposase and inactivated derivatives
EHC69_RS27470	COG3316	Transposase and inactivated derivatives
EHC69_RS27570	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EHC69_RS27660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC69_RS27720	COG0714	Associated with various cellular activities
EHC69_RS27770	COG0681	Belongs to the peptidase S26 family
EHC69_RS27785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC69_RS27875	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC69_RS27960	COG1192	Involved in chromosome partitioning
EHC69_RS28095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC69_RS28260	COG3093	addiction module antidote protein HigA
EHC69_RS28265	COG3549	Plasmid maintenance system killer
EHC69_RS28285	COG2067	long-chain fatty acid transport protein
EHC69_RS28340	COG2003	Belongs to the UPF0758 family
EHC69_RS28580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC69_RS28695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC69_RS28720	COG2948	multi-organism process
EHC69_RS28730	COG3504	Conjugal transfer protein
EHC69_RS28735	COG3701	Conjugal transfer protein
EHC69_RS28745	COG4962	Type ii secretion system protein e
EHC69_RS28755	COG3451	type IV secretory pathway VirB4
EHC69_RS28760	COG5268	conjugation
EHC69_RS28795	COG1192	Involved in chromosome partitioning
EHC69_RS28885	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EHC69_RS28905	COG3706	GGDEF domain
EHC69_RS28965	COG5268	conjugation
EHC69_RS28970	COG3451	type IV secretory pathway VirB4
EHC69_RS28980	COG4962	Type ii secretion system protein e
EHC69_RS28995	COG3504	Conjugal transfer protein
EHC69_RS29030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC69_RS29305	COG0419	ATPase involved in DNA repair
EHC69_RS29330	COG1192	Involved in chromosome partitioning