locus-tag	class	description
J5O00_RS00005	COG2959	enzyme of heme biosynthesis
J5O00_RS00010	COG3071	HemY protein
J5O00_RS00050	COG0633	Ferredoxin
J5O00_RS00055	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J5O00_RS00070	COG3118	belongs to the thioredoxin family
J5O00_RS00075	COG0513	Belongs to the DEAD box helicase family
J5O00_RS00080	COG0248	Ppx GppA phosphatase
J5O00_RS00085	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J5O00_RS00095	COG0514	ATP-dependent DNA helicase (RecQ)
J5O00_RS00100	COG2962	Rard protein
J5O00_RS00110	COG1280	lysine exporter protein (LysE YggA)
J5O00_RS00115	COG0405	Gamma-glutamyltransferase
J5O00_RS00130	COG3220	belongs to the UPF0276 family
J5O00_RS00160	COG0006	proline dipeptidase activity
J5O00_RS00160	COG0006	proline dipeptidase activity
J5O00_RS00170	COG2022	thiamine diphosphate biosynthetic process
J5O00_RS00175	COG2104	thiamine diphosphate biosynthetic process
J5O00_RS00180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J5O00_RS00190	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J5O00_RS00195	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J5O00_RS00235	COG0328	RNA-DNA hybrid ribonuclease activity
J5O00_RS00430	COG3829	transcription factor binding
J5O00_RS00560	COG2003	Belongs to the UPF0758 family
J5O00_RS00565	COG4735	regulation of single-species biofilm formation
J5O00_RS00625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5O00_RS00630	COG1739	Uncharacterized protein family UPF0029
J5O00_RS00635	COG1024	Enoyl-CoA hydratase
J5O00_RS00635	COG1250	3-hydroxyacyl-CoA dehydrogenase
J5O00_RS00640	COG0183	Belongs to the thiolase family
J5O00_RS00645	COG0604	alcohol dehydrogenase
J5O00_RS00660	COG0425	Belongs to the sulfur carrier protein TusA family
J5O00_RS00670	COG2119	membrane
J5O00_RS00675	COG0752	glycyl-tRNA synthetase alpha subunit
J5O00_RS00680	COG0751	glycine-tRNA ligase activity
J5O00_RS00685	COG0366	Alpha amylase catalytic
J5O00_RS00690	COG3977	Valine--pyruvate aminotransferase
J5O00_RS00695	COG0071	Belongs to the small heat shock protein (HSP20) family
J5O00_RS00705	COG0187	DNA topoisomerase II activity
J5O00_RS00710	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J5O00_RS00715	COG0592	DNA-directed DNA polymerase activity
J5O00_RS00720	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5O00_RS00735	COG1126	abc transporter atp-binding protein
J5O00_RS00745	COG0594	ribonuclease P activity
J5O00_RS00755	COG0706	membrane insertase activity
J5O00_RS00760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J5O00_RS00765	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5O00_RS00770	COG0445	tRNA wobble uridine modification
J5O00_RS00775	COG0357	Ribosomal RNA small subunit methyltransferase G
J5O00_RS00780	COG1192	Involved in chromosome partitioning
J5O00_RS00785	COG1475	DNA binding
J5O00_RS00790	COG3312	ion transport
J5O00_RS00795	COG0356	it plays a direct role in the translocation of protons across the membrane
J5O00_RS00810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J5O00_RS00815	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J5O00_RS00820	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J5O00_RS00825	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J5O00_RS00830	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J5O00_RS00835	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J5O00_RS00840	COG0765	amino acid transport
J5O00_RS00845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5O00_RS00850	COG2814	Major facilitator Superfamily
J5O00_RS00855	COG0583	DNA-binding transcription factor activity
J5O00_RS00865	COG0129	dihydroxy-acid dehydratase activity
J5O00_RS00870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J5O00_RS00875	COG3978	acetolactate synthase activity
J5O00_RS00945	COG0204	Acyl-transferase
J5O00_RS00950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J5O00_RS00955	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J5O00_RS00965	COG3084	Protein conserved in bacteria
J5O00_RS00970	COG4326	sporulation control protein
J5O00_RS00975	COG1272	protein, Hemolysin III
J5O00_RS00985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5O00_RS00990	COG0569	domain protein
J5O00_RS00995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J5O00_RS00995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5O00_RS01000	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J5O00_RS01005	COG0242	peptide deformylase activity
J5O00_RS01015	COG0758	DNA mediated transformation
J5O00_RS01020	COG2922	Belongs to the Smg family
J5O00_RS01025	COG0551	DNA topoisomerase type I activity
J5O00_RS01030	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J5O00_RS01035	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J5O00_RS01040	COG0009	L-threonylcarbamoyladenylate synthase
J5O00_RS01045	COG0408	coproporphyrinogen oxidase activity
J5O00_RS01050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J5O00_RS01060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J5O00_RS01095	COG0583	DNA-binding transcription factor activity
J5O00_RS01100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J5O00_RS01105	COG2960	long-chain fatty acid transporting porin activity
J5O00_RS01110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5O00_RS01115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5O00_RS01165	COG4172	Belongs to the ABC transporter superfamily
J5O00_RS01170	COG0747	negative chemotaxis
J5O00_RS01175	COG0601	transmembrane transport
J5O00_RS01180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5O00_RS01215	COG1609	Transcriptional regulator
J5O00_RS01220	COG0583	DNA-binding transcription factor activity
J5O00_RS01235	COG0129	dihydroxy-acid dehydratase activity
J5O00_RS01240	COG3265	gluconokinase activity
J5O00_RS01245	COG2610	gluconate transmembrane transporter activity
J5O00_RS01250	COG0800	Aldolase
J5O00_RS01255	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J5O00_RS01260	COG0583	DNA-binding transcription factor activity
J5O00_RS01295	COG0640	Transcriptional regulator
J5O00_RS01335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J5O00_RS01340	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J5O00_RS01370	COG1404	Belongs to the peptidase S8 family
J5O00_RS01410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5O00_RS01415	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J5O00_RS01420	COG0339	signal peptide processing
J5O00_RS01425	COG1522	sequence-specific DNA binding
J5O00_RS01430	COG5001	Diguanylate cyclase
J5O00_RS01430	COG5002	protein histidine kinase activity
J5O00_RS01435	COG0742	ribosomal rna small subunit methyltransferase
J5O00_RS01450	COG0589	response to stress
J5O00_RS01455	COG1528	Iron-storage protein
J5O00_RS01465	COG2081	HI0933 family
J5O00_RS01525	COG0628	permease
J5O00_RS01540	COG1322	Protein conserved in bacteria
J5O00_RS01545	COG2226	methyltransferase
J5O00_RS01550	COG3165	ubiquinone biosynthetic process from chorismate
J5O00_RS01555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J5O00_RS01560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5O00_RS01565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5O00_RS01570	COG0805	protein transport
J5O00_RS01575	COG0084	hydrolase, TatD family'
J5O00_RS01595	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5O00_RS01595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5O00_RS01600	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J5O00_RS01630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J5O00_RS01640	COG2204	response regulator
J5O00_RS01645	COG3852	Histidine kinase
J5O00_RS01655	COG0174	glutamine synthetase
J5O00_RS01660	COG1217	gtp-binding protein TYPA
J5O00_RS01675	COG1295	ribonuclease BN
J5O00_RS01680	COG1490	D-aminoacyl-tRNA deacylase activity
J5O00_RS01685	COG0456	acetyltransferase
J5O00_RS01695	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
J5O00_RS01700	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J5O00_RS01705	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J5O00_RS01710	COG3031	protein transport across the cell outer membrane
J5O00_RS01720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5O00_RS01725	COG1459	type II secretion system
J5O00_RS01730	COG2165	general secretion pathway protein
J5O00_RS01735	COG2165	general secretion pathway protein
J5O00_RS01740	COG2165	general secretion pathway protein
J5O00_RS01745	COG4795	General secretion pathway protein
J5O00_RS01750	COG3156	type II secretion system protein K
J5O00_RS01755	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J5O00_RS01760	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J5O00_RS01770	COG1218	3'(2'),5'-bisphosphate nucleotidase
J5O00_RS01775	COG0494	nUDIX hydrolase
J5O00_RS01780	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J5O00_RS01780	COG0316	Belongs to the HesB IscA family
J5O00_RS01785	COG1040	competence protein
J5O00_RS01790	COG0596	Alpha beta hydrolase
J5O00_RS01800	COG2183	response to ionizing radiation
J5O00_RS01810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J5O00_RS01830	COG2233	PERMEase
J5O00_RS01835	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J5O00_RS01840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5O00_RS01845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J5O00_RS01850	COG1758	RNA polymerase activity
J5O00_RS01855	COG0194	GDP metabolic process
J5O00_RS01870	COG0848	biopolymer transport protein
J5O00_RS01875	COG0811	peptide transport
J5O00_RS01895	COG4174	ABC transporter (Permease)
J5O00_RS01900	COG4239	(ABC) transporter, permease
J5O00_RS01905	COG0747	negative chemotaxis
J5O00_RS01910	COG0444	Belongs to the ABC transporter superfamily
J5O00_RS01915	COG4608	Belongs to the ABC transporter superfamily
J5O00_RS01925	COG1561	YicC-like family, N-terminal region
J5O00_RS01930	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J5O00_RS01935	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J5O00_RS01940	COG1560	Kdo2-lipid A biosynthetic process
J5O00_RS01945	COG1309	transcriptional regulator
J5O00_RS01950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5O00_RS01960	COG2003	Belongs to the UPF0758 family
J5O00_RS01965	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J5O00_RS01980	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J5O00_RS01995	COG0438	transferase activity, transferring glycosyl groups
J5O00_RS02005	COG0859	PFAM glycosyl transferase family 9
J5O00_RS02010	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J5O00_RS02015	COG3642	lipopolysaccharide core region biosynthetic process
J5O00_RS02035	COG0110	maltose O-acetyltransferase activity
J5O00_RS02040	COG2030	dehydratase
J5O00_RS02060	COG0438	transferase activity, transferring glycosyl groups
J5O00_RS02060	COG0297	glycogen (starch) synthase activity
J5O00_RS02070	COG1519	Transferase
J5O00_RS02075	COG0859	PFAM glycosyl transferase family 9
J5O00_RS02080	COG1560	Kdo2-lipid A biosynthetic process
J5O00_RS02175	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5O00_RS02185	COG1215	transferase activity, transferring glycosyl groups
J5O00_RS02250	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5O00_RS02255	COG0149	triose-phosphate isomerase activity
J5O00_RS02280	COG1494	fructose-1,6-bisphosphatase
J5O00_RS02285	COG3074	FtsZ-dependent cytokinesis
J5O00_RS02290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J5O00_RS02295	COG1575	Belongs to the MenA family. Type 1 subfamily
J5O00_RS02325	COG2003	Belongs to the UPF0758 family
J5O00_RS02340	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J5O00_RS02345	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J5O00_RS02355	COG1609	Transcriptional regulator
J5O00_RS02360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J5O00_RS02365	COG0254	rRNA binding
J5O00_RS02375	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J5O00_RS02380	COG0088	Forms part of the polypeptide exit tunnel
J5O00_RS02390	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J5O00_RS02395	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J5O00_RS02400	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J5O00_RS02405	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J5O00_RS02415	COG0255	Belongs to the universal ribosomal protein uL29 family
J5O00_RS02420	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J5O00_RS02425	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J5O00_RS02430	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J5O00_RS02435	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J5O00_RS02440	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J5O00_RS02445	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J5O00_RS02450	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J5O00_RS02465	COG1841	ribosomal large subunit assembly
J5O00_RS02470	COG0200	Binds to the 23S rRNA
J5O00_RS02475	COG0201	protein transport
J5O00_RS02480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J5O00_RS02485	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J5O00_RS02490	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J5O00_RS02500	COG0202	RNA polymerase activity
J5O00_RS02505	COG0203	ribosomal protein L17
J5O00_RS02515	COG0545	Peptidyl-prolyl cis-trans isomerase
J5O00_RS02525	COG2153	protein acetylation
J5O00_RS02530	COG0513	Belongs to the DEAD box helicase family
J5O00_RS02540	COG0737	Belongs to the 5'-nucleotidase family
J5O00_RS02545	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J5O00_RS02545	COG1648	precorrin-2 dehydrogenase activity
J5O00_RS02550	COG0175	sulfate reduction
J5O00_RS02555	COG2895	sulfate adenylyltransferase (ATP) activity
J5O00_RS02560	COG0471	metal ion transport
J5O00_RS02560	COG3273	potassium ion transport
J5O00_RS02565	COG0529	Catalyzes the synthesis of activated sulfate
J5O00_RS02585	COG1136	(ABC) transporter
J5O00_RS02600	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J5O00_RS02610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5O00_RS02615	COG0729	surface antigen
J5O00_RS02620	COG2911	Protein conserved in bacteria
J5O00_RS02625	COG2105	PFAM AIG2 family protein
J5O00_RS02635	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J5O00_RS02640	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
J5O00_RS02645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5O00_RS02650	COG0163	prenyltransferase activity
J5O00_RS02655	COG4143	(ABC) transporter
J5O00_RS02660	COG1178	ABC-type Fe3 transport system permease component
J5O00_RS02665	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J5O00_RS02680	COG2358	TRAP transporter, solute receptor (TAXI family
J5O00_RS02690	COG0039	L-malate dehydrogenase activity
J5O00_RS02700	COG0142	geranyltranstransferase activity
J5O00_RS02705	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J5O00_RS02715	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J5O00_RS02720	COG2966	Psort location CytoplasmicMembrane, score
J5O00_RS02735	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J5O00_RS02740	COG2967	ApaG domain
J5O00_RS02745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J5O00_RS02750	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J5O00_RS02755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5O00_RS02760	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J5O00_RS02765	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J5O00_RS02775	COG0066	3-isopropylmalate dehydratase activity
J5O00_RS02780	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J5O00_RS02785	COG0473	3-isopropylmalate dehydrogenase activity
J5O00_RS02790	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5O00_RS02810	COG0583	DNA-binding transcription factor activity
J5O00_RS02815	COG1022	Amp-dependent synthetase and ligase
J5O00_RS02820	COG0028	Belongs to the TPP enzyme family
J5O00_RS02825	COG0440	acetolactate synthase activity
J5O00_RS02840	COG0469	pyruvate kinase activity
J5O00_RS02845	COG1349	DNA-binding transcription factor activity
J5O00_RS02850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J5O00_RS02865	COG5002	protein histidine kinase activity
J5O00_RS02870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5O00_RS02875	COG3722	fumarate hydratase activity
J5O00_RS02880	COG0246	Mannitol dehydrogenase
J5O00_RS02885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5O00_RS02885	COG2213	PTS system mannitol-specific
J5O00_RS02915	COG1464	Belongs to the NlpA lipoprotein family
J5O00_RS02990	COG1610	YqeY-like protein
J5O00_RS02995	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J5O00_RS03000	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J5O00_RS03005	COG0596	Alpha beta hydrolase
J5O00_RS03010	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J5O00_RS03015	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J5O00_RS03020	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J5O00_RS03025	COG1968	undecaprenyl-diphosphatase activity
J5O00_RS03030	COG0617	tRNA 3'-terminal CCA addition
J5O00_RS03035	COG3409	Peptidoglycan-binding domain 1 protein
J5O00_RS03035	COG3267	Type II secretory pathway component ExeA
J5O00_RS03045	COG4991	sh3 domain protein
J5O00_RS03050	COG0306	phosphate transporter
J5O00_RS03055	COG1392	Phosphate transport regulator
J5O00_RS03060	COG3025	triphosphatase activity
J5O00_RS03075	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J5O00_RS03080	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5O00_RS03080	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5O00_RS03085	COG1538	Outer membrane efflux protein
J5O00_RS03090	COG0494	nUDIX hydrolase
J5O00_RS03095	COG3151	Protein conserved in bacteria
J5O00_RS03105	COG3150	esterase
J5O00_RS03115	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J5O00_RS03120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5O00_RS03130	COG3105	Protein conserved in bacteria
J5O00_RS03135	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J5O00_RS03140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J5O00_RS03145	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J5O00_RS03150	COG0723	plastoquinol--plastocyanin reductase activity
J5O00_RS03155	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J5O00_RS03160	COG2857	Cytochrome c1
J5O00_RS03165	COG0625	glutathione transferase activity
J5O00_RS03170	COG2969	positive regulation of protein catabolic process
J5O00_RS03175	COG2823	Periplasmic or secreted lipoprotein
J5O00_RS03180	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J5O00_RS03185	COG0792	nuclease activity
J5O00_RS03195	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J5O00_RS03205	COG0275	rRNA processing
J5O00_RS03210	COG3116	cell division
J5O00_RS03215	COG0768	penicillin binding
J5O00_RS03220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J5O00_RS03225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J5O00_RS03230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5O00_RS03235	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J5O00_RS03240	COG0772	Belongs to the SEDS family
J5O00_RS03245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J5O00_RS03250	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5O00_RS03255	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J5O00_RS03260	COG0849	cell division
J5O00_RS03265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J5O00_RS03270	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J5O00_RS03280	COG0653	protein targeting
J5O00_RS03285	COG0494	nUDIX hydrolase
J5O00_RS03290	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J5O00_RS03295	COG0505	Belongs to the CarA family
J5O00_RS03300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5O00_RS03310	COG0730	response to heat
J5O00_RS03315	COG0583	DNA-binding transcription factor activity
J5O00_RS03320	COG2860	membrane
J5O00_RS03325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J5O00_RS03335	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J5O00_RS03345	COG0493	'glutamate synthase
J5O00_RS03350	COG0067	glutamate synthase
J5O00_RS03350	COG0070	glutamate synthase
J5O00_RS03350	COG0069	glutamate synthase activity
J5O00_RS03360	COG0067	glutamate synthase
J5O00_RS03360	COG0069	glutamate synthase activity
J5O00_RS03360	COG0070	glutamate synthase
J5O00_RS03365	COG1242	4 iron, 4 sulfur cluster binding
J5O00_RS03370	COG2203	Gaf domain
J5O00_RS03370	COG3706	GGDEF domain
J5O00_RS03370	COG5001	Diguanylate cyclase
J5O00_RS03370	COG4251	negative regulation of phosphorylation
J5O00_RS03375	COG5002	protein histidine kinase activity
J5O00_RS03375	COG2198	Histidine kinase
J5O00_RS03375	COG0784	Response regulator, receiver
J5O00_RS03385	COG0745	RESPONSE REGULATOR receiver
J5O00_RS03395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J5O00_RS03410	COG0083	homoserine kinase activity
J5O00_RS03415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J5O00_RS03420	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
J5O00_RS03425	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J5O00_RS03430	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J5O00_RS03445	COG1115	amino acid carrier protein
J5O00_RS03450	COG3022	response to hydroperoxide
J5O00_RS03455	COG0513	Belongs to the DEAD box helicase family
J5O00_RS03460	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J5O00_RS03470	COG0716	FMN binding
J5O00_RS03475	COG4974	Belongs to the 'phage' integrase family
J5O00_RS03480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J5O00_RS03485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J5O00_RS03495	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J5O00_RS03500	COG2204	response regulator
J5O00_RS03510	COG0667	Aldo Keto reductase
J5O00_RS03520	COG3066	DNA modification
J5O00_RS03525	COG0494	nUDIX hydrolase
J5O00_RS03535	COG0730	response to heat
J5O00_RS03540	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J5O00_RS03545	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J5O00_RS03555	COG1283	sodium-dependent phosphate transmembrane transporter activity
J5O00_RS03560	COG0583	DNA-binding transcription factor activity
J5O00_RS03565	COG0640	Transcriptional regulator
J5O00_RS03570	COG0268	Binds directly to 16S ribosomal RNA
J5O00_RS03575	COG0728	peptidoglycan biosynthetic process
J5O00_RS03580	COG0196	riboflavin kinase activity
J5O00_RS03585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J5O00_RS03590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J5O00_RS03595	COG1047	Peptidyl-prolyl cis-trans
J5O00_RS03600	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J5O00_RS03605	COG3279	Response regulator of the LytR AlgR family
J5O00_RS03610	COG3275	phosphorelay sensor kinase activity
J5O00_RS03615	COG1966	Carbon starvation protein
J5O00_RS03630	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J5O00_RS03635	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J5O00_RS03640	COG1472	Belongs to the glycosyl hydrolase 3 family
J5O00_RS03645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J5O00_RS03650	COG0287	Prephenate dehydrogenase
J5O00_RS03650	COG1605	Chorismate mutase
J5O00_RS03655	COG0739	heme binding
J5O00_RS03665	COG0488	(ABC) transporter
J5O00_RS03675	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
J5O00_RS03680	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J5O00_RS03685	COG0077	Prephenate dehydratase
J5O00_RS03685	COG1605	Chorismate mutase
J5O00_RS03690	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J5O00_RS03695	COG0741	lytic transglycosylase activity
J5O00_RS03700	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5O00_RS03705	COG0564	pseudouridine synthase activity
J5O00_RS03715	COG0542	response to heat
J5O00_RS03770	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J5O00_RS03775	COG0826	peptidase U32
J5O00_RS03780	COG2974	May be involved in recombination
J5O00_RS03785	COG0745	RESPONSE REGULATOR receiver
J5O00_RS03790	COG5002	protein histidine kinase activity
J5O00_RS03800	COG0248	Ppx GppA phosphatase
J5O00_RS03805	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J5O00_RS03815	COG0581	inorganic phosphate transmembrane transporter activity
J5O00_RS03820	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5O00_RS03825	COG0704	Plays a role in the regulation of phosphate uptake
J5O00_RS03835	COG3142	Participates in the control of copper homeostasis
J5O00_RS03840	COG0450	alkyl hydroperoxide reductase
J5O00_RS03845	COG0583	DNA-binding transcription factor activity
J5O00_RS03850	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J5O00_RS03860	COG0517	IMP dehydrogenase activity
J5O00_RS03870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J5O00_RS03875	COG0343	queuine tRNA-ribosyltransferase activity
J5O00_RS03880	COG1862	Preprotein translocase
J5O00_RS03885	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5O00_RS03890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5O00_RS03895	COG0483	inositol monophosphate 1-phosphatase activity
J5O00_RS03910	COG1104	cysteine desulfurase activity
J5O00_RS03915	COG0822	iron-sulfur transferase activity
J5O00_RS03925	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J5O00_RS03930	COG0443	Heat shock 70 kDa protein
J5O00_RS03935	COG0633	Ferredoxin
J5O00_RS03940	COG2975	iron-sulfur cluster assembly
J5O00_RS03945	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J5O00_RS03950	COG0105	UTP biosynthetic process
J5O00_RS03955	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J5O00_RS03965	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J5O00_RS03970	COG0124	histidyl-tRNA synthetase
J5O00_RS03975	COG2976	Protein conserved in bacteria
J5O00_RS03980	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5O00_RS03985	COG1160	GTP binding
J5O00_RS04000	COG1570	exodeoxyribonuclease VII activity
J5O00_RS04005	COG0517	IMP dehydrogenase activity
J5O00_RS04005	COG0516	GMP reductase activity
J5O00_RS04010	COG0519	Catalyzes the synthesis of GMP from XMP
J5O00_RS04010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5O00_RS04015	COG1757	Na H antiporter
J5O00_RS04025	COG1584	GPR1 FUN34 yaaH family protein
J5O00_RS04070	COG2873	o-acetylhomoserine
J5O00_RS04075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J5O00_RS04095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5O00_RS04095	COG3153	acetyltransferase
J5O00_RS04100	COG0583	DNA-binding transcription factor activity
J5O00_RS04170	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J5O00_RS04175	COG2867	negative regulation of translational initiation
J5O00_RS04180	COG2914	Belongs to the UPF0125 (RnfH) family
J5O00_RS04185	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5O00_RS04190	COG0497	DNA recombination
J5O00_RS04200	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J5O00_RS04205	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J5O00_RS04215	COG0443	Heat shock 70 kDa protein
J5O00_RS04220	COG0484	heat shock protein binding
J5O00_RS04230	COG4969	Belongs to the N-Me-Phe pilin family
J5O00_RS04250	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J5O00_RS04260	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J5O00_RS04265	COG0047	phosphoribosylformylglycinamidine synthase activity
J5O00_RS04265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J5O00_RS04290	COG2195	Cleaves the N-terminal amino acid of tripeptides
J5O00_RS04295	COG2252	PERMEase
J5O00_RS04300	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J5O00_RS04305	COG1073	alpha beta
J5O00_RS04315	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J5O00_RS04320	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J5O00_RS04325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J5O00_RS04330	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5O00_RS04330	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5O00_RS04350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5O00_RS04355	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J5O00_RS04360	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J5O00_RS04365	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J5O00_RS04370	COG0142	geranyltranstransferase activity
J5O00_RS04375	COG1722	exodeoxyribonuclease VII activity
J5O00_RS04380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J5O00_RS04385	COG2885	chlorophyll binding
J5O00_RS04390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J5O00_RS04390	COG0301	tRNA thio-modification
J5O00_RS04395	COG0583	DNA-binding transcription factor activity
J5O00_RS04405	COG2363	Small membrane protein
J5O00_RS04410	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
J5O00_RS04420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5O00_RS04425	COG1611	Belongs to the LOG family
J5O00_RS04440	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J5O00_RS04440	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J5O00_RS04450	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
J5O00_RS04455	COG1464	Belongs to the NlpA lipoprotein family
J5O00_RS04460	COG2011	ABC-type metal ion transport system permease component
J5O00_RS04465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J5O00_RS04470	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J5O00_RS04480	COG1263	PTS System
J5O00_RS04480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J5O00_RS04485	COG0366	Alpha amylase catalytic
J5O00_RS04500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J5O00_RS04505	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5O00_RS04510	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J5O00_RS04515	COG0321	lipoyl(octanoyl) transferase activity
J5O00_RS04520	COG2921	Belongs to the UPF0250 family
J5O00_RS04525	COG1686	Belongs to the peptidase S11 family
J5O00_RS04530	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J5O00_RS04535	COG0772	Belongs to the SEDS family
J5O00_RS04540	COG0768	penicillin binding
J5O00_RS04545	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J5O00_RS04550	COG0799	negative regulation of ribosome biogenesis
J5O00_RS04555	COG1466	dna polymerase III delta subunit
J5O00_RS04560	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
J5O00_RS04565	COG0495	leucyl-tRNA aminoacylation
J5O00_RS04570	COG2888	peptidyl-tyrosine sulfation
J5O00_RS04575	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J5O00_RS04580	COG4535	Mg2 and Co2 transporter CorC
J5O00_RS04585	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J5O00_RS04590	COG1702	phosphate starvation-inducible protein PhoH
J5O00_RS04595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5O00_RS04600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5O00_RS04715	COG0012	GTP binding
J5O00_RS04720	COG0193	aminoacyl-tRNA hydrolase activity
J5O00_RS04725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J5O00_RS04730	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J5O00_RS04735	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J5O00_RS04740	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J5O00_RS04745	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J5O00_RS04750	COG2890	protein-(glutamine-N5) methyltransferase activity
J5O00_RS04755	COG3094	Invasion gene expression up-regulator, SirB
J5O00_RS04760	COG2912	Transglutaminase-like superfamily
J5O00_RS04765	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J5O00_RS04770	COG0737	Belongs to the 5'-nucleotidase family
J5O00_RS04780	COG1187	pseudouridine synthase activity
J5O00_RS04785	COG2840	Smr protein MutS2
J5O00_RS04820	COG2217	Heavy metal translocating P-type atpase
J5O00_RS04820	COG2608	mercury ion transmembrane transporter activity
J5O00_RS04830	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J5O00_RS04835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5O00_RS04885	COG0784	Response regulator, receiver
J5O00_RS04885	COG0835	chemotaxis
J5O00_RS04890	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J5O00_RS04895	COG1815	bacterial-type flagellum-dependent cell motility
J5O00_RS04900	COG1558	bacterial-type flagellum-dependent cell motility
J5O00_RS04910	COG1749	Flagellar hook protein flgE
J5O00_RS04915	COG4787	bacterial-type flagellum-dependent cell motility
J5O00_RS04925	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J5O00_RS04930	COG1706	bacterial-type flagellum-dependent cell motility
J5O00_RS04935	COG3951	Flagellar rod assembly protein muramidase FlgJ
J5O00_RS04935	COG1705	Flagellar rod assembly protein muramidase FlgJ
J5O00_RS04945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J5O00_RS04950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J5O00_RS04960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J5O00_RS04965	COG2190	(PTS) system
J5O00_RS04970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5O00_RS04975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5O00_RS04980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J5O00_RS04985	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
J5O00_RS04990	COG3115	cell septum assembly
J5O00_RS04995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J5O00_RS05015	COG0330	HflC and HflK could
J5O00_RS05020	COG3118	belongs to the thioredoxin family
J5O00_RS05025	COG0300	oxidoreductase activity
J5O00_RS05030	COG1090	epimerase
J5O00_RS05055	COG0622	Phosphoesterase
J5O00_RS05075	COG3710	Transcriptional regulator
J5O00_RS05080	COG0326	Molecular chaperone. Has ATPase activity
J5O00_RS05085	COG0563	adenylate kinase activity
J5O00_RS05090	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J5O00_RS05095	COG3104	oligopeptide transport
J5O00_RS05100	COG0250	Participates in transcription elongation, termination and antitermination
J5O00_RS05105	COG0367	asparagine synthase
J5O00_RS05110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5O00_RS05110	COG4651	solute:proton antiporter activity
J5O00_RS05115	COG1846	Transcriptional regulator
J5O00_RS05115	COG1940	carbohydrate kinase activity
J5O00_RS05120	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J5O00_RS05125	COG1263	PTS System
J5O00_RS05125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J5O00_RS05130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5O00_RS05135	COG0735	belongs to the Fur family
J5O00_RS05145	COG0716	FMN binding
J5O00_RS05155	COG0596	Alpha beta hydrolase
J5O00_RS05160	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
J5O00_RS05165	COG0033	Phosphoglucomutase
J5O00_RS05175	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J5O00_RS05190	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J5O00_RS05195	COG1053	succinate dehydrogenase
J5O00_RS05200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J5O00_RS05205	COG0567	Dehydrogenase, E1 component
J5O00_RS05210	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5O00_RS05215	COG0045	succinate-CoA ligase (ADP-forming) activity
J5O00_RS05225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5O00_RS05230	COG1121	(ABC) transporter
J5O00_RS05235	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J5O00_RS05240	COG4977	sequence-specific DNA binding
J5O00_RS05245	COG1918	ferrous iron import across plasma membrane
J5O00_RS05265	COG0018	arginyl-trna synthetase
J5O00_RS05270	COG3102	Protein conserved in bacteria
J5O00_RS05275	COG0788	formyltetrahydrofolate deformylase activity
J5O00_RS05280	COG1199	ATP-dependent helicase activity
J5O00_RS05285	COG1214	PFAM Peptidase M22, glycoprotease
J5O00_RS05300	COG2267	carboxylic ester hydrolase activity
J5O00_RS05305	COG0318	PFAM AMP-dependent synthetase and ligase
J5O00_RS05310	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J5O00_RS05315	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J5O00_RS05320	COG2894	cell division
J5O00_RS05325	COG0850	regulation of cytokinetic process
J5O00_RS05330	COG3100	YcgL domain-containing protein
J5O00_RS05335	COG2951	lytic endotransglycosylase activity
J5O00_RS05340	COG0583	DNA-binding transcription factor activity
J5O00_RS05345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J5O00_RS05350	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J5O00_RS05370	COG1028	Short-chain dehydrogenase reductase Sdr
J5O00_RS05380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5O00_RS05405	COG2986	histidine ammonia-lyase
J5O00_RS05410	COG1216	Glycosyl transferase, family 2
J5O00_RS05415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5O00_RS05430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5O00_RS05435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5O00_RS05470	COG1253	flavin adenine dinucleotide binding
J5O00_RS05475	COG0513	Belongs to the DEAD box helicase family
J5O00_RS05480	COG0569	domain protein
J5O00_RS05485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5O00_RS05500	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J5O00_RS05505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5O00_RS05510	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5O00_RS05515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5O00_RS05525	COG2204	response regulator
J5O00_RS05540	COG0544	peptidyl-prolyl cis-trans isomerase activity
J5O00_RS05550	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J5O00_RS05555	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J5O00_RS05560	COG0776	regulation of translation
J5O00_RS05565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5O00_RS05570	COG1555	photosystem II stabilization
J5O00_RS05585	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J5O00_RS05590	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
J5O00_RS05595	COG0436	Aminotransferase
J5O00_RS05600	COG1169	isochorismate synthase
J5O00_RS05610	COG0596	Alpha beta hydrolase
J5O00_RS05615	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J5O00_RS05635	COG2855	membrane
J5O00_RS05640	COG0477	Major facilitator Superfamily
J5O00_RS05685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5O00_RS05690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5O00_RS05715	COG1522	sequence-specific DNA binding
J5O00_RS05725	COG1946	Acyl-CoA thioesterase
J5O00_RS05730	COG3126	Type III secretion system lipoprotein chaperone (YscW)
J5O00_RS05745	COG2199	diguanylate cyclase activity
J5O00_RS05755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5O00_RS05760	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5O00_RS05765	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J5O00_RS05770	COG0516	GMP reductase activity
J5O00_RS05770	COG0517	IMP dehydrogenase activity
J5O00_RS05795	COG0537	adenosine 5'-monophosphoramidase activity
J5O00_RS05820	COG3150	esterase
J5O00_RS05825	COG1252	NADH dehydrogenase
J5O00_RS05840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J5O00_RS05850	COG4591	ABC-type transport system involved in lipoprotein release permease component
J5O00_RS05855	COG1136	(ABC) transporter
J5O00_RS05860	COG4591	ABC-type transport system involved in lipoprotein release permease component
J5O00_RS05870	COG2333	competence protein COMEC
J5O00_RS05870	COG0658	competence protein
J5O00_RS05875	COG1132	(ABC) transporter
J5O00_RS05880	COG1663	tetraacyldisaccharide 4'-kinase activity
J5O00_RS05890	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5O00_RS05895	COG2719	SpoVR family
J5O00_RS05900	COG2718	Belongs to the UPF0229 family
J5O00_RS05905	COG2766	serine protein kinase
J5O00_RS05910	COG3013	Belongs to the UPF0304 family
J5O00_RS05920	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J5O00_RS05930	COG1882	Formate acetyltransferase
J5O00_RS05970	COG0708	Exodeoxyribonuclease III
J5O00_RS05980	COG3923	Primosomal replication protein n
J5O00_RS05985	COG0730	response to heat
J5O00_RS05990	COG1199	ATP-dependent helicase activity
J5O00_RS06000	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J5O00_RS06005	COG1187	pseudouridine synthase activity
J5O00_RS06015	COG1278	Cold shock
J5O00_RS06020	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J5O00_RS06025	COG0542	response to heat
J5O00_RS06035	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J5O00_RS06040	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J5O00_RS06045	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J5O00_RS06055	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J5O00_RS06065	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J5O00_RS06070	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J5O00_RS06075	COG0297	glycogen (starch) synthase activity
J5O00_RS06095	COG3070	regulator of competence-specific genes
J5O00_RS06100	COG1609	Transcriptional regulator
J5O00_RS06105	COG3381	protein complex oligomerization
J5O00_RS06110	COG0745	RESPONSE REGULATOR receiver
J5O00_RS06115	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J5O00_RS06120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J5O00_RS06125	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
J5O00_RS06130	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
J5O00_RS06135	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J5O00_RS06155	COG0189	ligase activity
J5O00_RS06155	COG4067	protein conserved in archaea
J5O00_RS06160	COG0500	methyltransferase
J5O00_RS06165	COG4106	trans-aconitate 2-methyltransferase activity
J5O00_RS06170	COG1801	Protein of unknown function DUF72
J5O00_RS06175	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J5O00_RS06180	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J5O00_RS06185	COG0840	transmembrane signaling receptor activity
J5O00_RS06190	COG0632	four-way junction helicase activity
J5O00_RS06195	COG2255	four-way junction helicase activity
J5O00_RS06200	COG1271	oxidase subunit
J5O00_RS06205	COG1294	oxidase, subunit
J5O00_RS06210	COG4890	Cyd operon protein YbgT
J5O00_RS06220	COG0824	Thioesterase
J5O00_RS06225	COG0811	peptide transport
J5O00_RS06240	COG0823	Involved in the tonB-independent uptake of proteins
J5O00_RS06245	COG2885	chlorophyll binding
J5O00_RS06250	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
J5O00_RS06255	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J5O00_RS06265	COG3766	membrane
J5O00_RS06275	COG0754	glutathionylspermidine amidase activity
J5O00_RS06285	COG0784	Response regulator, receiver
J5O00_RS06285	COG5002	protein histidine kinase activity
J5O00_RS06320	COG0582	viral genome integration into host DNA
J5O00_RS06530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5O00_RS06535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5O00_RS06580	COG0840	transmembrane signaling receptor activity
J5O00_RS06585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5O00_RS06590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5O00_RS06615	COG3568	Endonuclease Exonuclease Phosphatase
J5O00_RS06630	COG0583	DNA-binding transcription factor activity
J5O00_RS06640	COG0686	Belongs to the AlaDH PNT family
J5O00_RS06650	COG1674	ftsk spoiiie
J5O00_RS06655	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J5O00_RS06660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J5O00_RS06665	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J5O00_RS06675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J5O00_RS06680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J5O00_RS06685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J5O00_RS06690	COG0156	8-amino-7-oxononanoate synthase activity
J5O00_RS06700	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J5O00_RS06710	COG0501	Belongs to the peptidase M48B family
J5O00_RS06720	COG0300	oxidoreductase activity
J5O00_RS06735	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J5O00_RS06755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J5O00_RS06760	COG2915	High frequency lysogenization protein hflD homolog
J5O00_RS06765	COG0482	sulfurtransferase activity
J5O00_RS06775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5O00_RS06785	COG1757	Na H antiporter
J5O00_RS06800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J5O00_RS06805	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J5O00_RS06810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5O00_RS06815	COG0131	Imidazoleglycerol-phosphate dehydratase
J5O00_RS06815	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J5O00_RS06820	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J5O00_RS06825	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J5O00_RS06830	COG0107	imidazoleglycerol-phosphate synthase activity
J5O00_RS06835	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J5O00_RS06835	COG0140	phosphoribosyl-ATP diphosphatase activity
J5O00_RS06840	COG3012	SEC-C Motif Domain Protein
J5O00_RS06845	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J5O00_RS06850	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5O00_RS06855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5O00_RS06860	COG0215	cysteine-tRNA ligase activity
J5O00_RS06865	COG1435	thymidine kinase activity
J5O00_RS06870	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J5O00_RS06895	COG2116	formate transmembrane transporter activity
J5O00_RS06905	COG0390	transport system, permease component
J5O00_RS06910	COG4459	periplasmic nitrate reductase
J5O00_RS06915	COG3005	denitrification pathway
J5O00_RS06920	COG0243	molybdopterin cofactor binding
J5O00_RS06935	COG1227	inorganic diphosphatase activity
J5O00_RS06945	COG4172	Belongs to the ABC transporter superfamily
J5O00_RS06955	COG4171	peptide transport system, permease
J5O00_RS06970	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J5O00_RS06975	COG1842	Phage shock protein A
J5O00_RS06990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5O00_RS07005	COG2818	Glycosylase
J5O00_RS07010	COG5380	lipid catabolic process
J5O00_RS07015	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J5O00_RS07020	COG0626	cystathionine gamma-synthase activity
J5O00_RS07030	COG0733	neurotransmitter:sodium symporter activity
J5O00_RS07040	COG0564	pseudouridine synthase activity
J5O00_RS07050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J5O00_RS07055	COG1151	hydroxylamine reductase activity
J5O00_RS07060	COG3604	Transcriptional regulator
J5O00_RS07070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J5O00_RS07075	COG4136	ATPase activity
J5O00_RS07080	COG4135	transport system, permease component
J5O00_RS07085	COG4134	Bacterial extracellular solute-binding protein
J5O00_RS07090	COG0398	Pfam SNARE associated Golgi protein
J5O00_RS07100	COG0493	'glutamate synthase
J5O00_RS07125	COG3313	Fe-S protein
J5O00_RS07150	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J5O00_RS07170	COG1061	Type III restriction enzyme res subunit
J5O00_RS07175	COG1187	pseudouridine synthase activity
J5O00_RS07180	COG2814	Major facilitator Superfamily
J5O00_RS07215	COG3005	denitrification pathway
J5O00_RS07220	COG0702	epimerase
J5O00_RS07225	COG0534	Mate efflux family protein
J5O00_RS07230	COG4181	ATPase activity
J5O00_RS07245	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J5O00_RS07260	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J5O00_RS07265	COG3273	potassium ion transport
J5O00_RS07265	COG2985	domain, Protein
J5O00_RS07270	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J5O00_RS07280	COG1737	Transcriptional regulator
J5O00_RS07285	COG0076	glutamate decarboxylase activity
J5O00_RS07295	COG2431	L-lysine efflux transmembrane transporter activity
J5O00_RS07305	COG3070	regulator of competence-specific genes
J5O00_RS07320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5O00_RS07320	COG4191	Histidine kinase
J5O00_RS07330	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J5O00_RS07335	COG3048	D-serine ammonia-lyase activity
J5O00_RS07340	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J5O00_RS07345	COG4988	ABC transporter
J5O00_RS07350	COG0492	ferredoxin-NADP+ reductase activity
J5O00_RS07375	COG0471	metal ion transport
J5O00_RS07380	COG2949	membrane
J5O00_RS07385	COG0281	malic enzyme
J5O00_RS07390	COG1643	Atp-dependent helicase
J5O00_RS07395	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
J5O00_RS07410	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J5O00_RS07445	COG0277	FAD linked oxidase domain protein
J5O00_RS07445	COG0247	lactate metabolic process
J5O00_RS07460	COG2986	histidine ammonia-lyase
J5O00_RS07465	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
J5O00_RS07470	COG0010	Belongs to the arginase family
J5O00_RS07475	COG1228	amidohydrolase
J5O00_RS07480	COG2188	Transcriptional regulator
J5O00_RS07495	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J5O00_RS07505	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J5O00_RS07515	COG0393	Putative heavy-metal-binding
J5O00_RS07545	COG3706	GGDEF domain
J5O00_RS07550	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J5O00_RS07555	COG0072	phenylalanine-tRNA ligase activity
J5O00_RS07555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5O00_RS07565	COG0776	regulation of translation
J5O00_RS07575	COG0500	methyltransferase
J5O00_RS07580	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J5O00_RS07585	COG0295	cytidine deaminase activity
J5O00_RS07590	COG1346	cytolysis
J5O00_RS07595	COG1380	Effector of murein hydrolase LrgA
J5O00_RS07600	COG2925	Exonuclease
J5O00_RS07605	COG1823	symporter activity
J5O00_RS07610	COG0702	epimerase
J5O00_RS07615	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J5O00_RS07620	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J5O00_RS07630	COG2062	phosphohistidine phosphatase, SixA
J5O00_RS07640	COG2988	succinylglutamate desuccinylase activity
J5O00_RS07645	COG4139	cobalamin transport
J5O00_RS07650	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
J5O00_RS07670	COG0583	DNA-binding transcription factor activity
J5O00_RS07690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J5O00_RS07695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5O00_RS07700	COG3475	LICD family
J5O00_RS07705	COG1451	nucleotide metabolic process
J5O00_RS07710	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
J5O00_RS07740	COG3938	Belongs to the proline racemase family
J5O00_RS07755	COG2423	ornithine cyclodeaminase activity
J5O00_RS07760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5O00_RS07765	COG3842	ATPase activity
J5O00_RS07770	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5O00_RS07775	COG1177	transmembrane transport
J5O00_RS07785	COG3291	Pkd domain containing protein
J5O00_RS07800	COG0444	Belongs to the ABC transporter superfamily
J5O00_RS07805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5O00_RS07810	COG0601	transmembrane transport
J5O00_RS07820	COG2195	Cleaves the N-terminal amino acid of tripeptides
J5O00_RS07830	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J5O00_RS07840	COG0625	glutathione transferase activity
J5O00_RS07905	COG0583	DNA-binding transcription factor activity
J5O00_RS07940	COG0471	metal ion transport
J5O00_RS07945	COG4191	Histidine kinase
J5O00_RS07945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5O00_RS07955	COG5001	Diguanylate cyclase
J5O00_RS07955	COG3300	MHYT domain
J5O00_RS07965	COG1280	lysine exporter protein (LysE YggA)
J5O00_RS07970	COG1328	CTP reductase activity
J5O00_RS07975	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J5O00_RS07985	COG0861	Integral membrane protein TerC family
J5O00_RS07990	COG0739	heme binding
J5O00_RS08030	COG3501	Rhs element vgr protein
J5O00_RS08055	COG0515	serine threonine protein kinase
J5O00_RS08090	COG1522	sequence-specific DNA binding
J5O00_RS08160	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J5O00_RS08170	COG0814	amino acid
J5O00_RS08190	COG1132	(ABC) transporter
J5O00_RS08195	COG1132	(ABC) transporter
J5O00_RS08220	COG0443	Heat shock 70 kDa protein
J5O00_RS08225	COG0443	Heat shock 70 kDa protein
J5O00_RS08235	COG3706	GGDEF domain
J5O00_RS08265	COG0243	molybdopterin cofactor binding
J5O00_RS08270	COG0437	4 iron, 4 sulfur cluster binding
J5O00_RS08275	COG3302	dmso reductase anchor subunit
J5O00_RS08290	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J5O00_RS08295	COG1643	Atp-dependent helicase
J5O00_RS08310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J5O00_RS08320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5O00_RS08325	COG1215	transferase activity, transferring glycosyl groups
J5O00_RS08330	COG0438	transferase activity, transferring glycosyl groups
J5O00_RS08360	COG0438	transferase activity, transferring glycosyl groups
J5O00_RS08370	COG2204	response regulator
J5O00_RS08400	COG1793	dna ligase
J5O00_RS08410	COG0534	Mate efflux family protein
J5O00_RS08415	COG0307	riboflavin synthase, alpha
J5O00_RS08425	COG3001	Fructosamine kinase
J5O00_RS08430	COG2201	protein-glutamate methylesterase activity
J5O00_RS08435	COG3706	GGDEF domain
J5O00_RS08445	COG0791	NLP P60 protein
J5O00_RS08450	COG0840	transmembrane signaling receptor activity
J5O00_RS08450	COG3290	protein histidine kinase activity
J5O00_RS08485	COG3148	PFAM DTW domain containing protein
J5O00_RS08490	COG1940	carbohydrate kinase activity
J5O00_RS08500	COG0303	'Molybdopterin
J5O00_RS08505	COG0746	molybdenum cofactor guanylyltransferase activity
J5O00_RS08510	COG3842	ATPase activity
J5O00_RS08525	COG2204	response regulator
J5O00_RS08530	COG4191	Histidine kinase
J5O00_RS08535	COG0488	(ABC) transporter
J5O00_RS08540	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J5O00_RS08560	COG3381	protein complex oligomerization
J5O00_RS08570	COG0243	molybdopterin cofactor binding
J5O00_RS08570	COG3383	formate dehydrogenase (NAD+) activity
J5O00_RS08575	COG0437	4 iron, 4 sulfur cluster binding
J5O00_RS08600	COG0004	ammonium transporteR
J5O00_RS08610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J5O00_RS08615	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J5O00_RS08625	COG1177	transmembrane transport
J5O00_RS08635	COG3842	ATPase activity
J5O00_RS08655	COG0037	tRNA processing
J5O00_RS08660	COG0589	response to stress
J5O00_RS08665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5O00_RS08680	COG2217	Heavy metal translocating P-type atpase
J5O00_RS08690	COG2010	Cytochrome c
J5O00_RS08705	COG3278	Belongs to the heme-copper respiratory oxidase family
J5O00_RS08720	COG0784	Response regulator, receiver
J5O00_RS08720	COG2205	protein histidine kinase activity
J5O00_RS08770	COG4128	Pfam Zonular occludens toxin
J5O00_RS08860	COG3120	sequence-specific DNA binding
J5O00_RS08865	COG1067	ATP-dependent peptidase activity
J5O00_RS08870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5O00_RS08885	COG0488	(ABC) transporter
J5O00_RS08895	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5O00_RS08895	COG0116	Belongs to the methyltransferase superfamily
J5O00_RS08905	COG0167	dihydroorotate dehydrogenase activity
J5O00_RS08910	COG2902	Dehydrogenase
J5O00_RS08920	COG0308	aminopeptidase N
J5O00_RS08935	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J5O00_RS08940	COG1956	GAF domain-containing protein
J5O00_RS08945	COG1132	(ABC) transporter
J5O00_RS08950	COG2995	paraquat-inducible protein a
J5O00_RS08955	COG3008	intermembrane lipid transfer
J5O00_RS08960	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J5O00_RS08960	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
J5O00_RS08980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J5O00_RS08985	COG1666	GTP binding
J5O00_RS08995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5O00_RS09000	COG4597	amino acid ABC transporter
J5O00_RS09005	COG0765	amino acid transport
J5O00_RS09010	COG1126	abc transporter atp-binding protein
J5O00_RS09015	COG0670	Belongs to the BI1 family
J5O00_RS09025	COG2920	part of a sulfur-relay system
J5O00_RS09030	COG1254	Belongs to the acylphosphatase family
J5O00_RS09035	COG0840	transmembrane signaling receptor activity
J5O00_RS09040	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5O00_RS09105	COG3706	GGDEF domain
J5O00_RS09110	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J5O00_RS09115	COG0602	queuosine metabolic process
J5O00_RS09120	COG0561	phosphatase activity
J5O00_RS09145	COG2828	Protein conserved in bacteria
J5O00_RS09155	COG0372	Belongs to the citrate synthase family
J5O00_RS09160	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J5O00_RS09190	COG0730	response to heat
J5O00_RS09210	COG0457	Tetratricopeptide repeat
J5O00_RS09280	COG4790	Type iii secretion
J5O00_RS09285	COG4794	Type iii secretion
J5O00_RS09290	COG4791	protein targeting
J5O00_RS09295	COG4792	protein secretion
J5O00_RS09305	COG1073	alpha beta
J5O00_RS09310	COG1073	alpha beta
J5O00_RS09340	COG3177	Filamentation induced by cAMP protein fic
J5O00_RS09360	COG4669	(LipO)protein
J5O00_RS09430	COG1012	belongs to the aldehyde dehydrogenase family
J5O00_RS09435	COG3284	Transcriptional regulator
J5O00_RS09460	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J5O00_RS09465	COG0363	glucosamine-6-phosphate deaminase activity
J5O00_RS09470	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J5O00_RS09480	COG4565	transcriptional regulatory protein
J5O00_RS09485	COG3290	protein histidine kinase activity
J5O00_RS09500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5O00_RS09515	COG1858	cytochrome C peroxidase
J5O00_RS09520	COG0527	aspartate kinase activity
J5O00_RS09525	COG0662	Cupin 2, conserved barrel domain protein
J5O00_RS09530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J5O00_RS09535	COG0456	acetyltransferase
J5O00_RS09540	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J5O00_RS09560	COG4176	ABC-type proline glycine betaine transport system permease component
J5O00_RS09565	COG2113	Glycine betaine
J5O00_RS09585	COG1028	Short-chain dehydrogenase reductase Sdr
J5O00_RS09595	COG0745	RESPONSE REGULATOR receiver
J5O00_RS09600	COG0642	Histidine kinase
J5O00_RS09605	COG1368	sulfuric ester hydrolase activity
J5O00_RS09630	COG1115	amino acid carrier protein
J5O00_RS09640	COG1280	lysine exporter protein (LysE YggA)
J5O00_RS09645	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J5O00_RS09650	COG1560	Kdo2-lipid A biosynthetic process
J5O00_RS09655	COG0531	amino acid
J5O00_RS09665	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J5O00_RS09670	COG3063	Type IV pilus biogenesis stability protein PilW
J5O00_RS09700	COG0110	maltose O-acetyltransferase activity
J5O00_RS09720	COG2315	Protein conserved in bacteria
J5O00_RS09725	COG1846	Transcriptional regulator
J5O00_RS09740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5O00_RS09750	COG2200	EAL domain
J5O00_RS09750	COG2771	luxR family
J5O00_RS09755	COG1227	inorganic diphosphatase activity
J5O00_RS09760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J5O00_RS09765	COG1012	belongs to the aldehyde dehydrogenase family
J5O00_RS09770	COG2957	Belongs to the agmatine deiminase family
J5O00_RS09780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5O00_RS09785	COG1012	belongs to the aldehyde dehydrogenase family
J5O00_RS09790	COG1396	sequence-specific DNA binding
J5O00_RS09790	COG1917	Cupin 2, conserved barrel domain protein
J5O00_RS09795	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J5O00_RS09800	COG0174	glutamine synthetase
J5O00_RS09805	COG1757	Na H antiporter
J5O00_RS09855	COG2026	Addiction module toxin, RelE StbE family
J5O00_RS09900	COG4735	regulation of single-species biofilm formation
J5O00_RS10015	COG0346	lactoylglutathione lyase activity
J5O00_RS10255	COG2026	Addiction module toxin, RelE StbE family
J5O00_RS10390	COG0346	lactoylglutathione lyase activity
J5O00_RS10425	COG0384	phenazine biosynthesis protein PhzF
J5O00_RS10620	COG1335	isochorismatase
J5O00_RS10725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J5O00_RS10735	COG3768	UPF0283 membrane protein
J5O00_RS10740	COG3106	COG3106 Predicted ATPase
J5O00_RS10755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5O00_RS10760	COG0784	Response regulator, receiver
J5O00_RS10760	COG2205	protein histidine kinase activity
J5O00_RS10770	COG0494	nUDIX hydrolase
J5O00_RS10775	COG0814	amino acid
J5O00_RS10780	COG1760	l-serine dehydratase
J5O00_RS10785	COG2200	EAL domain
J5O00_RS10795	COG0720	synthase
J5O00_RS10805	COG0017	Asparaginyl-tRNA synthetase
J5O00_RS10815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5O00_RS10830	COG1448	Aminotransferase
J5O00_RS10850	COG0840	transmembrane signaling receptor activity
J5O00_RS10855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J5O00_RS10860	COG1846	Transcriptional regulator
J5O00_RS10885	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5O00_RS10900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5O00_RS10905	COG3108	Peptidase M15
J5O00_RS10910	COG2989	Protein conserved in bacteria
J5O00_RS10935	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5O00_RS10945	COG4235	cytochrome complex assembly
J5O00_RS10945	COG3088	subunit of a heme lyase
J5O00_RS10955	COG1138	Cytochrome C-type biogenesis protein
J5O00_RS10960	COG3301	Polysulphide reductase, NrfD
J5O00_RS10965	COG0437	4 iron, 4 sulfur cluster binding
J5O00_RS10975	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J5O00_RS10995	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J5O00_RS11000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5O00_RS11005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5O00_RS11030	COG0019	diaminopimelate decarboxylase activity
J5O00_RS11070	COG0322	excinuclease ABC activity
J5O00_RS11075	COG2197	response regulator
J5O00_RS11080	COG0417	DNA replication proofreading
J5O00_RS11090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J5O00_RS11095	COG3099	Belongs to the UPF0263 family
J5O00_RS11100	COG1187	pseudouridine synthase activity
J5O00_RS11110	COG0009	L-threonylcarbamoyladenylate synthase
J5O00_RS11115	COG0613	PHP domain protein
J5O00_RS11125	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5O00_RS11130	COG0512	Glutamine amidotransferase of anthranilate synthase
J5O00_RS11135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5O00_RS11140	COG0135	phosphoribosylanthranilate isomerase activity
J5O00_RS11140	COG0134	indole-3-glycerol-phosphate synthase activity
J5O00_RS11145	COG0133	tryptophan synthase activity
J5O00_RS11150	COG0159	tryptophan synthase activity
J5O00_RS11155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5O00_RS11160	COG0318	PFAM AMP-dependent synthetase and ligase
J5O00_RS11165	COG1301	dicarboxylic acid transport
J5O00_RS11185	COG2917	probably involved in intracellular septation
J5O00_RS11195	COG2350	Protein conserved in bacteria
J5O00_RS11205	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J5O00_RS11210	COG0583	DNA-binding transcription factor activity
J5O00_RS11225	COG3706	GGDEF domain
J5O00_RS11225	COG4251	negative regulation of phosphorylation
J5O00_RS11225	COG5001	Diguanylate cyclase
J5O00_RS11225	COG2203	Gaf domain
J5O00_RS11230	COG1032	radical SAM domain protein
J5O00_RS11235	COG0840	transmembrane signaling receptor activity
J5O00_RS11240	COG0745	RESPONSE REGULATOR receiver
J5O00_RS11245	COG5002	protein histidine kinase activity
J5O00_RS11245	COG3850	Histidine kinase
J5O00_RS11295	COG1335	isochorismatase
J5O00_RS11300	COG1136	(ABC) transporter
J5O00_RS11300	COG0577	efflux transmembrane transporter activity
J5O00_RS11305	COG1136	(ABC) transporter
J5O00_RS11305	COG0577	efflux transmembrane transporter activity
J5O00_RS11310	COG1136	(ABC) transporter
J5O00_RS11310	COG0577	efflux transmembrane transporter activity
J5O00_RS11320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5O00_RS11345	COG3118	belongs to the thioredoxin family
J5O00_RS11350	COG4232	protein-disulfide reductase activity
J5O00_RS11390	COG2863	cytochrome
J5O00_RS11395	COG3258	Cytochrome c
J5O00_RS11400	COG2995	paraquat-inducible protein a
J5O00_RS11405	COG3008	intermembrane lipid transfer
J5O00_RS11405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5O00_RS11415	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J5O00_RS11440	COG4166	transmembrane transport
J5O00_RS11445	COG0284	orotidine-5'-phosphate decarboxylase activity
J5O00_RS11450	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J5O00_RS11455	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
J5O00_RS11465	COG0539	negative regulation of cytoplasmic translation
J5O00_RS11470	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J5O00_RS11475	COG0616	signal peptide processing
J5O00_RS11480	COG1028	Short-chain dehydrogenase reductase Sdr
J5O00_RS11495	COG0587	DNA-directed DNA polymerase activity
J5O00_RS11500	COG0784	Response regulator, receiver
J5O00_RS11500	COG0835	chemotaxis
J5O00_RS11505	COG1940	carbohydrate kinase activity
J5O00_RS11510	COG0469	pyruvate kinase activity
J5O00_RS11515	COG4667	esterase of the alpha-beta hydrolase superfamily
J5O00_RS11530	COG0733	neurotransmitter:sodium symporter activity
J5O00_RS11545	COG1263	PTS System
J5O00_RS11545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J5O00_RS11550	COG0084	hydrolase, TatD family'
J5O00_RS11560	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J5O00_RS11565	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J5O00_RS11595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5O00_RS11600	COG0416	fatty acid biosynthetic process
J5O00_RS11610	COG1399	metal-binding, possibly nucleic acid-binding protein
J5O00_RS11615	COG0424	maF-like protein
J5O00_RS11620	COG0564	pseudouridine synthase activity
J5O00_RS11625	COG1530	ribonuclease E activity
J5O00_RS11630	COG0659	secondary active sulfate transmembrane transporter activity
J5O00_RS11635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5O00_RS11640	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
J5O00_RS11650	COG0572	uridine kinase
J5O00_RS11655	COG0489	protein tyrosine kinase activity
J5O00_RS11660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5O00_RS11660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5O00_RS11670	COG2186	Transcriptional regulator
J5O00_RS11675	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J5O00_RS11680	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J5O00_RS11685	COG0653	protein targeting
J5O00_RS11690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5O00_RS11700	COG0366	Alpha amylase catalytic
J5O00_RS11705	COG1122	ATPase activity
J5O00_RS11710	COG4120	Belongs to the binding-protein-dependent transport system permease family
J5O00_RS11720	COG3092	negative regulation of chromosome organization
J5O00_RS11725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J5O00_RS11730	COG0280	phosphate acetyltransferase
J5O00_RS11730	COG0857	belongs to the CobB CobQ family
J5O00_RS11735	COG3174	membrane
J5O00_RS11745	COG0435	Glutathione S-transferase
J5O00_RS11755	COG0444	Belongs to the ABC transporter superfamily
J5O00_RS11760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5O00_RS11765	COG0601	transmembrane transport
J5O00_RS11775	COG0314	molybdopterin synthase activity
J5O00_RS11780	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J5O00_RS11785	COG0315	cyclic pyranopterin monophosphate synthase activity
J5O00_RS11790	COG0521	Mo-molybdopterin cofactor biosynthetic process
J5O00_RS11795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J5O00_RS11800	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J5O00_RS11805	COG2198	Histidine kinase
J5O00_RS11810	COG2204	response regulator
J5O00_RS11815	COG0556	nucleotide-excision repair
J5O00_RS11825	COG4657	Part of a membrane complex involved in electron transport
J5O00_RS11830	COG2878	Part of a membrane complex involved in electron transport
J5O00_RS11835	COG4656	Part of a membrane complex involved in electron transport
J5O00_RS11840	COG4658	electron transport chain
J5O00_RS11845	COG4659	FMN binding
J5O00_RS11850	COG4660	Part of a membrane complex involved in electron transport
J5O00_RS11855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J5O00_RS11860	COG0346	lactoylglutathione lyase activity
J5O00_RS11870	COG2885	chlorophyll binding
J5O00_RS11875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J5O00_RS11880	COG2056	Na+-H+ antiporter family
J5O00_RS11890	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J5O00_RS11910	COG1012	belongs to the aldehyde dehydrogenase family
J5O00_RS11910	COG1454	alcohol dehydrogenase
J5O00_RS11915	COG2095	MarC family integral membrane protein
J5O00_RS11920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5O00_RS11925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J5O00_RS11930	COG1757	Na H antiporter
J5O00_RS11945	COG3081	Nucleoid-associated protein
J5O00_RS11950	COG3082	Protein of unknown function (DUF1414)
J5O00_RS11955	COG3083	sulfuric ester hydrolase activity
J5O00_RS11965	COG0123	including yeast histone deacetylase and acetoin utilization protein
J5O00_RS11980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J5O00_RS11985	COG0778	Nitroreductase
J5O00_RS11990	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5O00_RS11990	COG1902	pentaerythritol trinitrate reductase activity
J5O00_RS11995	COG0616	signal peptide processing
J5O00_RS12000	COG0252	asparaginase activity
J5O00_RS12005	COG3139	Protein of unknown function (DUF1315)
J5O00_RS12015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5O00_RS12020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J5O00_RS12035	COG2226	methyltransferase
J5O00_RS12050	COG1785	Belongs to the alkaline phosphatase family
J5O00_RS12060	COG0346	lactoylglutathione lyase activity
J5O00_RS12065	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J5O00_RS12070	COG0668	transmembrane transport
J5O00_RS12075	COG2983	Belongs to the UPF0260 family
J5O00_RS12080	COG2261	transglycosylase associated protein
J5O00_RS12095	COG3681	Belongs to the UPF0597 family
J5O00_RS12100	COG0251	oxidation-reduction process
J5O00_RS12105	COG0814	amino acid
J5O00_RS12110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J5O00_RS12115	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J5O00_RS12120	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J5O00_RS12130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J5O00_RS12135	COG2832	Protein of unknown function (DUF454)
J5O00_RS12140	COG0745	RESPONSE REGULATOR receiver
J5O00_RS12145	COG0583	DNA-binding transcription factor activity
J5O00_RS12150	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J5O00_RS12155	COG1286	toxin biosynthetic process
J5O00_RS12160	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
J5O00_RS12165	COG0285	dihydrofolate synthase activity
J5O00_RS12170	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J5O00_RS12175	COG0101	tRNA pseudouridine synthase activity
J5O00_RS12185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J5O00_RS12190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5O00_RS12195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5O00_RS12200	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
J5O00_RS12200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5O00_RS12205	COG0431	NADPH-dependent FMN reductase
J5O00_RS12215	COG3101	peptidyl-lysine hydroxylation
J5O00_RS12220	COG2860	membrane
J5O00_RS12225	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J5O00_RS12230	COG2890	protein-(glutamine-N5) methyltransferase activity
J5O00_RS12235	COG2840	Smr protein MutS2
J5O00_RS12240	COG2062	phosphohistidine phosphatase, SixA
J5O00_RS12255	COG1024	Enoyl-CoA hydratase
J5O00_RS12255	COG1250	3-hydroxyacyl-CoA dehydrogenase
J5O00_RS12260	COG0183	Belongs to the thiolase family
J5O00_RS12285	COG2853	Lipoprotein
J5O00_RS12300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5O00_RS12305	COG1138	Cytochrome C-type biogenesis protein
J5O00_RS12310	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
J5O00_RS12315	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5O00_RS12320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5O00_RS12325	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5O00_RS12330	COG4133	protoheme IX ABC transporter activity
J5O00_RS12340	COG0835	chemotaxis
J5O00_RS12350	COG1192	Involved in chromosome partitioning
J5O00_RS12355	COG2201	protein-glutamate methylesterase activity
J5O00_RS12360	COG0784	Response regulator, receiver
J5O00_RS12360	COG0643	Histidine kinase
J5O00_RS12360	COG2198	Histidine kinase
J5O00_RS12365	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J5O00_RS12405	COG1987	bacterial-type flagellum assembly
J5O00_RS12455	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J5O00_RS12465	COG1677	Flagellar hook-basal body complex protein FliE
J5O00_RS12485	COG1516	flagellar protein fliS
J5O00_RS12495	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J5O00_RS12500	COG1334	flagellar protein FlaG
J5O00_RS12505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J5O00_RS12510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J5O00_RS12515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J5O00_RS12520	COG2837	iron assimilation
J5O00_RS12545	COG1393	Belongs to the ArsC family
J5O00_RS12550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5O00_RS12565	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J5O00_RS12570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5O00_RS12575	COG2716	regulation of RNA biosynthetic process
J5O00_RS12580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J5O00_RS12595	COG4783	chaperone-mediated protein folding
J5O00_RS12600	COG1393	Belongs to the ArsC family
J5O00_RS12620	COG2233	PERMEase
J5O00_RS12625	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J5O00_RS12630	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J5O00_RS12635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J5O00_RS12640	COG0121	glutamine amidotransferase
J5O00_RS12645	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J5O00_RS12650	COG1960	acyl-CoA dehydrogenase activity
J5O00_RS12675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J5O00_RS12680	COG0328	RNA-DNA hybrid ribonuclease activity
J5O00_RS12685	COG2226	methyltransferase
J5O00_RS12690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5O00_RS12695	COG0741	lytic transglycosylase activity
J5O00_RS12695	COG1388	LysM domain
J5O00_RS12705	COG3021	interspecies interaction between organisms
J5O00_RS12710	COG0347	Belongs to the P(II) protein family
J5O00_RS12720	COG0037	tRNA processing
J5O00_RS12725	COG0825	malonyl-CoA metabolic process
J5O00_RS12730	COG0587	DNA-directed DNA polymerase activity
J5O00_RS12735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J5O00_RS12740	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5O00_RS12745	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5O00_RS12750	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5O00_RS12755	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5O00_RS12760	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
J5O00_RS12770	COG0750	zinc metalloprotease
J5O00_RS12775	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J5O00_RS12780	COG0575	Belongs to the CDS family
J5O00_RS12785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J5O00_RS12790	COG0233	cytoplasmic translational termination
J5O00_RS12795	COG0528	UMP kinase activity
J5O00_RS12800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J5O00_RS12805	COG0052	Belongs to the universal ribosomal protein uS2 family
J5O00_RS12810	COG0024	Methionine aminopeptidase
J5O00_RS12815	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J5O00_RS12825	COG0564	pseudouridine synthase activity
J5O00_RS12830	COG3098	single-species biofilm formation
J5O00_RS12855	COG1671	Belongs to the UPF0178 family
J5O00_RS12860	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J5O00_RS12870	COG0254	rRNA binding
J5O00_RS12875	COG1720	tRNA m6t6A37 methyltransferase activity
J5O00_RS12880	COG0442	prolyl-tRNA aminoacylation
J5O00_RS12900	COG0733	neurotransmitter:sodium symporter activity
J5O00_RS12915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J5O00_RS12920	COG0514	ATP-dependent DNA helicase (RecQ)
J5O00_RS12925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5O00_RS12930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5O00_RS12970	COG0494	nUDIX hydrolase
J5O00_RS13055	COG4974	Belongs to the 'phage' integrase family
J5O00_RS13130	COG1477	protein flavinylation
J5O00_RS13135	COG2871	sodium ion transport
J5O00_RS13140	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J5O00_RS13145	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J5O00_RS13150	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J5O00_RS13155	COG1805	sodium ion transport
J5O00_RS13160	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J5O00_RS13165	COG0271	Belongs to the BolA IbaG family
J5O00_RS13170	COG2813	Specifically methylates the guanine in position
J5O00_RS13175	COG3056	Lipoprotein
J5O00_RS13195	COG1595	DNA-templated transcription, initiation
J5O00_RS13215	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J5O00_RS13220	COG0693	protein deglycase activity
J5O00_RS13225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J5O00_RS13230	COG3706	GGDEF domain
J5O00_RS13235	COG2166	iron-sulfur cluster assembly
J5O00_RS13240	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J5O00_RS13245	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J5O00_RS13255	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5O00_RS13255	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J5O00_RS13265	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J5O00_RS13270	COG1074	ATP-dependent DNA helicase activity
J5O00_RS13275	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J5O00_RS13295	COG3141	response to X-ray
J5O00_RS13300	COG2171	N-acyltransferase activity
J5O00_RS13305	COG0584	glycerophosphoryl diester phosphodiesterase
J5O00_RS13310	COG2271	Major facilitator Superfamily
J5O00_RS13315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J5O00_RS13320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J5O00_RS13330	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J5O00_RS13335	COG0598	Magnesium transport protein CorA
J5O00_RS13350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5O00_RS13355	COG1609	Transcriptional regulator
J5O00_RS13360	COG2176	DNA-directed DNA polymerase activity
J5O00_RS13375	COG2017	converts alpha-aldose to the beta-anomer
J5O00_RS13380	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J5O00_RS13385	COG1085	galactose-1-phosphate uridylyltransferase
J5O00_RS13390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5O00_RS13395	COG1609	Transcriptional regulator
J5O00_RS13400	COG3250	beta-galactosidase activity
J5O00_RS13405	COG2731	YhcH YjgK YiaL family protein
J5O00_RS13415	COG0583	DNA-binding transcription factor activity
J5O00_RS13450	COG1022	Amp-dependent synthetase and ligase
J5O00_RS13460	COG0583	DNA-binding transcription factor activity
J5O00_RS13465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J5O00_RS13470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J5O00_RS13480	COG0560	Phosphoserine phosphatase
J5O00_RS13490	COG0813	purine-nucleoside phosphorylase activity
J5O00_RS13495	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J5O00_RS13500	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J5O00_RS13505	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J5O00_RS13510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J5O00_RS13515	COG0084	hydrolase, TatD family'
J5O00_RS13525	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J5O00_RS13545	COG3153	acetyltransferase
J5O00_RS13550	COG3154	lipid carrier protein
J5O00_RS13560	COG0826	peptidase U32
J5O00_RS13565	COG0826	peptidase U32
J5O00_RS13570	COG0534	Mate efflux family protein
J5O00_RS13585	COG1185	polyribonucleotide nucleotidyltransferase activity
J5O00_RS13590	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J5O00_RS13595	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J5O00_RS13600	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J5O00_RS13605	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J5O00_RS13610	COG0195	Participates in both transcription termination and antitermination
J5O00_RS13615	COG0779	Required for maturation of 30S ribosomal subunits
J5O00_RS13630	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J5O00_RS13635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5O00_RS13640	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J5O00_RS13645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J5O00_RS13650	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J5O00_RS13655	COG1534	Rna-binding protein
J5O00_RS13660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J5O00_RS13665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5O00_RS13670	COG2027	D-alanyl-D-alanine carboxypeptidase
J5O00_RS13680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J5O00_RS13685	COG0739	heme binding
J5O00_RS13690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5O00_RS13700	COG0316	Belongs to the HesB IscA family
J5O00_RS13705	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J5O00_RS13710	COG0628	permease
J5O00_RS13715	COG2813	Specifically methylates the guanine in position
J5O00_RS13720	COG0784	Response regulator, receiver
J5O00_RS13720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5O00_RS13720	COG2198	Histidine kinase
J5O00_RS13720	COG2205	protein histidine kinase activity
J5O00_RS13725	COG0747	negative chemotaxis
J5O00_RS13735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5O00_RS13740	COG0444	Belongs to the ABC transporter superfamily
J5O00_RS13745	COG4608	Belongs to the ABC transporter superfamily
J5O00_RS13755	COG2971	BadF BadG BcrA BcrD
J5O00_RS13770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5O00_RS13775	COG3842	ATPase activity
J5O00_RS13785	COG1840	ABC-type Fe3 transport system, periplasmic component
J5O00_RS13790	COG0004	ammonium transporteR
J5O00_RS13800	COG3112	Uncharacterised protein family (UPF0231)
J5O00_RS13805	COG1049	propionate catabolic process, 2-methylcitrate cycle
J5O00_RS13810	COG1752	Esterase of the alpha-beta hydrolase superfamily
J5O00_RS13815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5O00_RS13820	COG1643	Atp-dependent helicase
J5O00_RS13825	COG1489	DNA binding
J5O00_RS13835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5O00_RS13845	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J5O00_RS13850	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J5O00_RS13855	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J5O00_RS13860	COG1560	Kdo2-lipid A biosynthetic process
J5O00_RS13865	COG0842	Transport permease protein
J5O00_RS13870	COG1131	(ABC) transporter
J5O00_RS13875	COG0659	secondary active sulfate transmembrane transporter activity
J5O00_RS13880	COG0288	reversible hydration of carbon dioxide
J5O00_RS13895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5O00_RS13900	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5O00_RS13905	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J5O00_RS13910	COG2186	Transcriptional regulator
J5O00_RS13920	COG0157	Belongs to the NadC ModD family
J5O00_RS13930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5O00_RS13935	COG1459	type II secretion system
J5O00_RS13945	COG0237	dephospho-CoA kinase activity
J5O00_RS13950	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J5O00_RS13955	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J5O00_RS13960	COG0335	large ribosomal subunit rRNA binding
J5O00_RS13965	COG0336	Belongs to the RNA methyltransferase TrmD family
J5O00_RS13970	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J5O00_RS13975	COG0228	four-way junction DNA binding
J5O00_RS13980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J5O00_RS13985	COG4137	Cytochrome C assembly protein
J5O00_RS13990	COG4536	flavin adenine dinucleotide binding
J5O00_RS13995	COG1854	S-ribosylhomocysteine lyase activity
J5O00_RS14005	COG2918	glutathione biosynthetic process
J5O00_RS14010	COG0612	Peptidase, M16
J5O00_RS14015	COG1238	metal cluster binding
J5O00_RS14025	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J5O00_RS14030	COG0511	ligase activity, forming carbon-carbon bonds
J5O00_RS14030	COG5016	pyruvate
J5O00_RS14035	COG3630	sodium ion export across plasma membrane
J5O00_RS14090	COG0527	aspartate kinase activity
J5O00_RS14095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5O00_RS14100	COG2137	regulation of response to DNA damage stimulus
J5O00_RS14105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J5O00_RS14110	COG1546	Belongs to the CinA family
J5O00_RS14115	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J5O00_RS14120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J5O00_RS14130	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J5O00_RS14135	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J5O00_RS14140	COG0585	pseudouridine synthase activity
J5O00_RS14145	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5O00_RS14150	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J5O00_RS14155	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J5O00_RS14160	COG0148	phosphopyruvate hydratase activity
J5O00_RS14165	COG0504	CTP synthase activity
J5O00_RS14170	COG3956	TIGRFAM MazG family protein
J5O00_RS14175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J5O00_RS14190	COG0736	holo-[acyl-carrier-protein] synthase activity
J5O00_RS14195	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J5O00_RS14200	COG1381	Involved in DNA repair and RecF pathway recombination
J5O00_RS14205	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J5O00_RS14210	COG0571	ribonuclease III activity
J5O00_RS14220	COG0481	GTPase activity
J5O00_RS14225	COG3086	response to oxidative stress
J5O00_RS14235	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
J5O00_RS14240	COG1595	DNA-templated transcription, initiation
J5O00_RS14245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J5O00_RS14250	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J5O00_RS14255	COG0354	folic acid binding
J5O00_RS14270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5O00_RS14275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5O00_RS14280	COG3079	Belongs to the UPF0149 family
J5O00_RS14285	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
J5O00_RS14295	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J5O00_RS14300	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J5O00_RS14305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5O00_RS14315	COG0583	DNA-binding transcription factor activity
J5O00_RS14325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J5O00_RS14330	COG0668	transmembrane transport
J5O00_RS14335	COG0191	fructose-bisphosphate aldolase activity
J5O00_RS14340	COG0126	phosphoglycerate kinase activity
J5O00_RS14345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J5O00_RS14350	COG4771	TonB-dependent receptor
J5O00_RS14355	COG0583	DNA-binding transcription factor activity
J5O00_RS14360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J5O00_RS14365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J5O00_RS14375	COG3091	SprT-like family
J5O00_RS14380	COG2356	endonuclease I
J5O00_RS14385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J5O00_RS14390	COG0189	ligase activity
J5O00_RS14395	COG1678	Uncharacterized ACR, COG1678
J5O00_RS14400	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J5O00_RS14415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J5O00_RS14420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J5O00_RS14425	COG0762	integral membrane protein
J5O00_RS14430	COG1872	DUF167
J5O00_RS14440	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J5O00_RS14445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J5O00_RS14450	COG2066	Belongs to the glutaminase family
J5O00_RS14460	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J5O00_RS14470	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J5O00_RS14475	COG0741	lytic transglycosylase activity
J5O00_RS14545	COG1012	belongs to the aldehyde dehydrogenase family
J5O00_RS14585	COG3437	response regulator, receiver
J5O00_RS14595	COG3394	polysaccharide catabolic process
J5O00_RS14600	COG1486	melibiose metabolic process
J5O00_RS14605	COG1447	Phosphotransferase system cellobiose-specific component IIA
J5O00_RS14610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J5O00_RS14615	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J5O00_RS14620	COG0726	polysaccharide deacetylase
J5O00_RS14630	COG1028	Short-chain dehydrogenase reductase Sdr
J5O00_RS14645	COG0795	lipopolysaccharide-transporting ATPase activity
J5O00_RS14650	COG0795	lipopolysaccharide-transporting ATPase activity
J5O00_RS14655	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J5O00_RS14660	COG2927	DNA polymerase III (CHI subunit)
J5O00_RS14665	COG0525	valine-tRNA ligase activity
J5O00_RS14690	COG2235	arginine
J5O00_RS14695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J5O00_RS14705	COG0540	Belongs to the ATCase OTCase family
J5O00_RS14710	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J5O00_RS14715	COG0251	oxidation-reduction process
J5O00_RS14720	COG0204	Acyl-transferase
J5O00_RS14725	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J5O00_RS14730	COG5007	Belongs to the BolA IbaG family
J5O00_RS14740	COG2854	intermembrane phospholipid transfer
J5O00_RS14745	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5O00_RS14750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J5O00_RS14755	COG1127	ABC transporter
J5O00_RS14765	COG0517	IMP dehydrogenase activity
J5O00_RS14765	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J5O00_RS14775	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J5O00_RS14780	COG1137	ATPase activity
J5O00_RS14790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J5O00_RS14795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5O00_RS14800	COG1660	Displays ATPase and GTPase activities
J5O00_RS14805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5O00_RS14810	COG2239	Acts as a magnesium transporter
J5O00_RS14815	COG0312	modulator of DNA gyrase
J5O00_RS14820	COG3028	Belongs to the UPF0307 family
J5O00_RS14825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5O00_RS14830	COG0564	pseudouridine synthase activity
J5O00_RS14840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5O00_RS14845	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J5O00_RS14850	COG0312	modulator of DNA gyrase
J5O00_RS14855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5O00_RS14860	COG3164	Protein of unknown function
J5O00_RS14870	COG0424	maF-like protein
J5O00_RS14875	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J5O00_RS14880	COG1792	Involved in formation and maintenance of cell shape
J5O00_RS14885	COG1077	Cell shape determining protein MreB Mrl
J5O00_RS14930	COG1459	type II secretion system
J5O00_RS14935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5O00_RS14945	COG3267	Type II secretory pathway component ExeA
J5O00_RS14945	COG3409	Peptidoglycan-binding domain 1 protein
J5O00_RS14970	COG2199	diguanylate cyclase activity
J5O00_RS14970	COG2200	EAL domain
J5O00_RS14975	COG0629	single-stranded DNA binding
J5O00_RS14990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5O00_RS15000	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J5O00_RS15005	COG0527	aspartate kinase activity
J5O00_RS15010	COG0646	methionine synthase
J5O00_RS15010	COG1410	methionine synthase
J5O00_RS15055	COG0175	sulfate reduction
J5O00_RS15060	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J5O00_RS15065	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5O00_RS15085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5O00_RS15090	COG0735	belongs to the Fur family
J5O00_RS15100	COG0166	Belongs to the GPI family
J5O00_RS15105	COG0432	Pfam Uncharacterised protein family UPF0047
J5O00_RS15115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5O00_RS15130	COG0359	binds to the 23S rRNA
J5O00_RS15140	COG2965	DNA replication, synthesis of RNA primer
J5O00_RS15145	COG0360	Binds together with S18 to 16S ribosomal RNA
J5O00_RS15150	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J5O00_RS15155	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J5O00_RS15165	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5O00_RS15170	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J5O00_RS15200	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J5O00_RS15210	COG0678	peroxiredoxin activity
J5O00_RS15210	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J5O00_RS15220	COG0165	Argininosuccinate lyase
J5O00_RS15220	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J5O00_RS15225	COG0137	argininosuccinate synthase activity
J5O00_RS15230	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5O00_RS15235	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J5O00_RS15240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5O00_RS15245	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J5O00_RS15255	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J5O00_RS15260	COG0460	homoserine dehydrogenase
J5O00_RS15260	COG0527	aspartate kinase activity
J5O00_RS15265	COG0626	cystathionine gamma-synthase activity
J5O00_RS15275	COG0281	malic enzyme
J5O00_RS15285	COG2906	2 iron, 2 sulfur cluster binding
J5O00_RS15290	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5O00_RS15295	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J5O00_RS15300	COG0049	tRNA binding
J5O00_RS15315	COG2923	Belongs to the DsrF TusC family
J5O00_RS15320	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J5O00_RS15325	COG2964	Protein conserved in bacteria
J5O00_RS15330	COG0545	Peptidyl-prolyl cis-trans isomerase
J5O00_RS15340	COG2900	Belongs to the SlyX family
J5O00_RS15345	COG1446	asparaginase
J5O00_RS15350	COG1047	Peptidyl-prolyl cis-trans
J5O00_RS15365	COG2249	NAD(P)H dehydrogenase (quinone) activity
J5O00_RS15370	COG0488	(ABC) transporter
J5O00_RS15380	COG0429	hydrolase of the alpha beta-hydrolase fold
J5O00_RS15385	COG3089	Belongs to the UPF0270 family
J5O00_RS15390	COG3954	Phosphoribulokinase
J5O00_RS15395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5O00_RS15405	COG1012	belongs to the aldehyde dehydrogenase family
J5O00_RS15415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J5O00_RS15420	COG0512	Glutamine amidotransferase of anthranilate synthase
J5O00_RS15435	COG0180	Tryptophanyl-tRNA synthetase
J5O00_RS15440	COG0546	phosphoglycolate phosphatase activity
J5O00_RS15445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5O00_RS15450	COG0557	exoribonuclease II activity
J5O00_RS15455	COG1959	2 iron, 2 sulfur cluster binding
J5O00_RS15460	COG1017	nitric oxide dioxygenase activity
J5O00_RS15460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J5O00_RS15465	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J5O00_RS15470	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J5O00_RS15475	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
J5O00_RS15480	COG0330	HflC and HflK could
J5O00_RS15485	COG0330	HflC and HflK could
J5O00_RS15490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J5O00_RS15500	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J5O00_RS15505	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J5O00_RS15515	COG0802	atpase or kinase
J5O00_RS15520	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5O00_RS15590	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J5O00_RS15595	COG1162	GTPase activity
J5O00_RS15600	COG0688	phosphatidylethanolamine metabolic process
J5O00_RS15605	COG0471	metal ion transport
J5O00_RS15620	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J5O00_RS15625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J5O00_RS15630	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
J5O00_RS15635	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5O00_RS15640	COG1045	serine acetyltransferase
J5O00_RS15645	COG4942	peptidase
J5O00_RS15665	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J5O00_RS15670	COG1053	succinate dehydrogenase
J5O00_RS15675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J5O00_RS15680	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J5O00_RS15685	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J5O00_RS15695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J5O00_RS15700	COG1509	lysine 2,3-aminomutase activity
J5O00_RS15705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5O00_RS15720	COG0459	protein refolding
J5O00_RS15730	COG0534	Mate efflux family protein
J5O00_RS15735	COG0205	6-phosphofructokinase activity
J5O00_RS15745	COG3678	ATP-independent chaperone mediated protein folding
J5O00_RS15750	COG0745	RESPONSE REGULATOR receiver
J5O00_RS15755	COG2205	protein histidine kinase activity
J5O00_RS15765	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J5O00_RS15770	COG3030	protein affecting phage T7 exclusion by the F plasmid
J5O00_RS15775	COG1027	Aspartate ammonia-lyase
J5O00_RS15780	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J5O00_RS15785	COG4232	protein-disulfide reductase activity
J5O00_RS15795	COG3263	regulation of cellular component size
J5O00_RS15805	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5O00_RS15825	COG0784	Response regulator, receiver
J5O00_RS15825	COG2198	Histidine kinase
J5O00_RS15825	COG2205	protein histidine kinase activity
J5O00_RS15830	COG2814	Major facilitator Superfamily
J5O00_RS15845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J5O00_RS15850	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J5O00_RS15855	COG0511	ligase activity, forming carbon-carbon bonds
J5O00_RS15860	COG0439	Biotin carboxylase
J5O00_RS15865	COG2264	protein methyltransferase activity
J5O00_RS15870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5O00_RS15875	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J5O00_RS15880	COG2814	Major facilitator Superfamily
J5O00_RS15885	COG0488	(ABC) transporter
J5O00_RS15890	COG3706	GGDEF domain
J5O00_RS15960	COG1982	Orn Lys Arg decarboxylase major
J5O00_RS15965	COG0531	amino acid
J5O00_RS15970	COG3710	Transcriptional regulator
J5O00_RS15975	COG0789	Transcriptional regulator
J5O00_RS15980	COG0138	bifunctional purine biosynthesis protein purh
J5O00_RS15985	COG0151	Belongs to the GarS family
J5O00_RS16000	COG1253	flavin adenine dinucleotide binding
J5O00_RS16010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5O00_RS16015	COG1573	uracil-dna glycosylase
J5O00_RS16020	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J5O00_RS16035	COG2816	NAD+ diphosphatase activity
J5O00_RS16040	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
J5O00_RS16045	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J5O00_RS16050	COG0085	RNA polymerase activity
J5O00_RS16055	COG0222	ribosome binding
J5O00_RS16060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J5O00_RS16065	COG0081	regulation of translation
J5O00_RS16070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J5O00_RS16075	COG0250	Participates in transcription elongation, termination and antitermination
J5O00_RS16080	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J5O00_RS16085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5O00_RS16120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J5O00_RS16130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5O00_RS16185	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J5O00_RS16215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5O00_RS16220	COG0534	Mate efflux family protein
J5O00_RS16225	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
J5O00_RS16230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J5O00_RS16235	COG2937	Belongs to the GPAT DAPAT family
J5O00_RS16240	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J5O00_RS16245	COG3161	chorismate lyase activity
J5O00_RS16250	COG1580	Controls the rotational direction of flagella during chemotaxis
J5O00_RS16255	COG0705	Rhomboid family
J5O00_RS16260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J5O00_RS16270	COG2177	Part of the ABC transporter FtsEX involved in
J5O00_RS16275	COG2884	Cell division ATP-binding protein ftsE
J5O00_RS16280	COG0552	protein localization to endoplasmic reticulum
J5O00_RS16285	COG0742	ribosomal rna small subunit methyltransferase
J5O00_RS16295	COG2095	MarC family integral membrane protein
J5O00_RS16345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J5O00_RS16350	COG0640	Transcriptional regulator
J5O00_RS16355	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J5O00_RS16360	COG1280	lysine exporter protein (LysE YggA)
J5O00_RS16365	COG2267	carboxylic ester hydrolase activity
J5O00_RS16370	COG0561	phosphatase activity
J5O00_RS16385	COG3148	PFAM DTW domain containing protein
J5O00_RS16390	COG2199	diguanylate cyclase activity
J5O00_RS16390	COG2200	EAL domain
J5O00_RS16390	COG3287	FIST C domain
J5O00_RS16395	COG1011	Hydrolase
J5O00_RS16400	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J5O00_RS16410	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J5O00_RS16415	COG0019	diaminopimelate decarboxylase activity
J5O00_RS16425	COG1965	Belongs to the frataxin family
J5O00_RS16430	COG3072	Adenylate cyclase
J5O00_RS16435	COG0181	hydroxymethylbilane synthase activity
J5O00_RS16440	COG1587	Uroporphyrinogen-III synthase
J5O00_RS16455	COG1028	Short-chain dehydrogenase reductase Sdr
J5O00_RS16470	COG0456	acetyltransferase
J5O00_RS16490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5O00_RS16495	COG1929	Belongs to the glycerate kinase type-1 family
J5O00_RS16500	COG2610	gluconate transmembrane transporter activity
J5O00_RS16505	COG3835	regulator
J5O00_RS16530	COG0546	phosphoglycolate phosphatase activity
J5O00_RS16545	COG0583	DNA-binding transcription factor activity
J5O00_RS16555	COG0583	DNA-binding transcription factor activity
J5O00_RS16565	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
J5O00_RS16570	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
J5O00_RS16570	COG3408	Glycogen debranching enzyme
J5O00_RS16600	COG3047	cAMP biosynthetic process
J5O00_RS16605	COG1357	PFAM Pentapeptide repeats (8 copies)
J5O00_RS16635	COG2375	cellular response to nickel ion
J5O00_RS16640	COG0823	Involved in the tonB-independent uptake of proteins
J5O00_RS16645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5O00_RS16665	COG0800	Aldolase
J5O00_RS16670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5O00_RS16685	COG1917	Cupin 2, conserved barrel domain protein
J5O00_RS16695	COG1028	Short-chain dehydrogenase reductase Sdr
J5O00_RS16700	COG1414	Transcriptional regulator
J5O00_RS16715	COG0583	DNA-binding transcription factor activity
J5O00_RS16720	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J5O00_RS16725	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J5O00_RS16745	COG2199	diguanylate cyclase activity
J5O00_RS16755	COG0561	phosphatase activity
J5O00_RS16760	COG0583	DNA-binding transcription factor activity
J5O00_RS16775	COG0564	pseudouridine synthase activity
J5O00_RS16780	COG0534	Mate efflux family protein
J5O00_RS16785	COG5001	Diguanylate cyclase
J5O00_RS16795	COG3123	guanosine phosphorylase activity
J5O00_RS16835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J5O00_RS16845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5O00_RS16850	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J5O00_RS16860	COG2259	Doxx family
J5O00_RS16865	COG1741	Belongs to the pirin family
J5O00_RS16885	COG0363	glucosamine-6-phosphate deaminase activity
J5O00_RS16895	COG0786	glutamate:sodium symporter activity
J5O00_RS16900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5O00_RS16905	COG1131	(ABC) transporter
J5O00_RS16915	COG0786	glutamate:sodium symporter activity
J5O00_RS16940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5O00_RS16950	COG3279	Response regulator of the LytR AlgR family
J5O00_RS16955	COG3275	phosphorelay sensor kinase activity
J5O00_RS16985	COG0772	Belongs to the SEDS family
J5O00_RS16990	COG0217	transcriptional regulatory protein
J5O00_RS17010	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
J5O00_RS17010	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5O00_RS17020	COG0444	Belongs to the ABC transporter superfamily
J5O00_RS17025	COG4608	Belongs to the ABC transporter superfamily
J5O00_RS17050	COG1444	tRNA N-acetyltransferase activity
J5O00_RS17070	COG3340	Belongs to the peptidase S51 family
J5O00_RS17075	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5O00_RS17080	COG1263	PTS System
J5O00_RS17080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J5O00_RS17085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J5O00_RS17145	COG0259	pyridoxamine-phosphate oxidase activity
J5O00_RS17170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5O00_RS17215	COG1132	(ABC) transporter
J5O00_RS17225	COG2207	Transcriptional regulator
J5O00_RS17260	COG1486	melibiose metabolic process
J5O00_RS17265	COG0583	DNA-binding transcription factor activity
J5O00_RS17280	COG1595	DNA-templated transcription, initiation
J5O00_RS17305	COG3634	alkyl hydroperoxide reductase activity
J5O00_RS17315	COG1846	Transcriptional regulator
J5O00_RS17320	COG1764	response to oxidative stress
J5O00_RS17340	COG0463	Glycosyl transferase, family 2
J5O00_RS17360	COG0826	peptidase U32
J5O00_RS17385	COG1653	transport
J5O00_RS17390	COG0019	diaminopimelate decarboxylase activity
J5O00_RS17395	COG4264	IucA IucC family
J5O00_RS17420	COG4772	TonB-dependent receptor
J5O00_RS17425	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J5O00_RS17430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5O00_RS17435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5O00_RS17440	COG1120	ATPase activity
J5O00_RS17445	COG0840	transmembrane signaling receptor activity
J5O00_RS17450	COG0612	Peptidase, M16
J5O00_RS17460	COG0739	heme binding
J5O00_RS17470	COG2814	Major facilitator Superfamily
J5O00_RS17505	COG2356	endonuclease I
J5O00_RS17525	COG1982	Orn Lys Arg decarboxylase major
J5O00_RS17530	COG0531	amino acid
J5O00_RS17540	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J5O00_RS17550	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J5O00_RS17555	COG1162	GTPase activity
J5O00_RS17560	COG1263	PTS System
J5O00_RS17560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J5O00_RS17570	COG1999	signal sequence binding
J5O00_RS17585	COG2909	trisaccharide binding
J5O00_RS17590	COG0058	SHG alpha-glucan phosphorylase activity
J5O00_RS17595	COG1640	4-alpha-glucanotransferase
J5O00_RS17600	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J5O00_RS17605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5O00_RS17610	COG0366	Alpha amylase catalytic
J5O00_RS17620	COG3366	ferrous iron transmembrane transporter activity
J5O00_RS17625	COG0700	Nucleoside recognition
J5O00_RS17630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5O00_RS17635	COG3339	Conserved Protein
J5O00_RS17640	COG1301	dicarboxylic acid transport
J5O00_RS17650	COG0583	DNA-binding transcription factor activity
J5O00_RS17905	COG3012	SEC-C Motif Domain Protein
J5O00_RS17940	COG3081	Nucleoid-associated protein
J5O00_RS17980	COG2842	Transposition protein
J5O00_RS18040	COG2095	MarC family integral membrane protein
J5O00_RS18045	COG4667	esterase of the alpha-beta hydrolase superfamily
J5O00_RS18050	COG3397	chitin binding
J5O00_RS18055	COG1054	Belongs to the UPF0176 family
J5O00_RS18070	COG1686	Belongs to the peptidase S11 family
J5O00_RS18095	COG0583	DNA-binding transcription factor activity
J5O00_RS18100	COG4628	conserved protein (DUF2132)
J5O00_RS18125	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J5O00_RS18130	COG0628	permease
J5O00_RS18170	COG2814	Major facilitator Superfamily
J5O00_RS18185	COG0454	-acetyltransferase
J5O00_RS18195	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J5O00_RS18205	COG1882	Formate acetyltransferase
J5O00_RS18250	COG1360	Flagellar Motor Protein
J5O00_RS18255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J5O00_RS18260	COG1191	sigma factor activity
J5O00_RS18265	COG1580	Controls the rotational direction of flagella during chemotaxis
J5O00_RS18280	COG1516	flagellar protein fliS
J5O00_RS18285	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J5O00_RS18295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J5O00_RS18310	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J5O00_RS18320	COG1987	bacterial-type flagellum assembly
J5O00_RS18400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J5O00_RS18420	COG0346	lactoylglutathione lyase activity
J5O00_RS18445	COG0745	RESPONSE REGULATOR receiver
J5O00_RS18465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5O00_RS18475	COG0156	8-amino-7-oxononanoate synthase activity
J5O00_RS18480	COG1063	alcohol dehydrogenase
J5O00_RS18515	COG0668	transmembrane transport
J5O00_RS18525	COG1304	FMN binding
J5O00_RS18530	COG1620	l-lactate permease
J5O00_RS18535	COG0583	DNA-binding transcription factor activity
J5O00_RS18540	COG1505	serine-type exopeptidase activity
J5O00_RS18545	COG4172	Belongs to the ABC transporter superfamily
J5O00_RS18555	COG1067	ATP-dependent peptidase activity
J5O00_RS18580	COG1247	-acetyltransferase
J5O00_RS18585	COG0437	4 iron, 4 sulfur cluster binding
J5O00_RS18590	COG0348	domain, Protein
J5O00_RS18605	COG1122	ATPase activity
J5O00_RS18610	COG4720	Psort location CytoplasmicMembrane, score
J5O00_RS18615	COG1566	PFAM secretion protein HlyD family protein
J5O00_RS18625	COG3706	GGDEF domain
J5O00_RS18640	COG0813	purine-nucleoside phosphorylase activity
J5O00_RS18645	COG3272	Protein of unknown function (DUF1722)
J5O00_RS18650	COG0789	Transcriptional regulator
J5O00_RS18655	COG0415	Belongs to the DNA photolyase family
J5O00_RS18660	COG1376	ErfK ybiS ycfS ynhG family protein
J5O00_RS18660	COG1388	LysM domain
J5O00_RS18670	COG0513	Belongs to the DEAD box helicase family
J5O00_RS18675	COG1770	oligopeptidase
J5O00_RS18680	COG4771	TonB-dependent receptor
J5O00_RS18710	COG0573	inorganic phosphate transmembrane transporter activity
J5O00_RS18715	COG0581	inorganic phosphate transmembrane transporter activity
J5O00_RS18720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5O00_RS18735	COG2304	oxidoreductase activity
J5O00_RS18755	COG0714	Associated with various cellular activities
J5O00_RS18760	COG0840	transmembrane signaling receptor activity
J5O00_RS18770	COG2197	response regulator
J5O00_RS18820	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J5O00_RS18825	COG1120	ATPase activity
J5O00_RS18830	COG4774	siderophore transport
J5O00_RS18835	COG1132	(ABC) transporter
J5O00_RS18840	COG2205	protein histidine kinase activity
J5O00_RS18840	COG2205	protein histidine kinase activity
J5O00_RS18850	COG0569	domain protein
J5O00_RS18855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5O00_RS18865	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
J5O00_RS18870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5O00_RS18885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J5O00_RS18885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J5O00_RS18885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5O00_RS18890	COG2207	Transcriptional regulator
J5O00_RS18900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J5O00_RS18905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J5O00_RS18910	COG2084	Dehydrogenase
J5O00_RS18915	COG0753	catalase activity
J5O00_RS18925	COG2130	NADP-dependent
J5O00_RS18930	COG1309	transcriptional regulator
J5O00_RS18935	COG3097	Belongs to the UPF0267 family
J5O00_RS18990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5O00_RS18995	COG3842	ATPase activity
J5O00_RS19005	COG1175	transmembrane transport
J5O00_RS19010	COG3833	ABC-type maltose transport systems, permease component
J5O00_RS19030	COG3746	phosphate-selective porin O and P
J5O00_RS19045	COG1028	Short-chain dehydrogenase reductase Sdr
J5O00_RS19065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J5O00_RS19075	COG0625	glutathione transferase activity
J5O00_RS19080	COG1686	Belongs to the peptidase S11 family
J5O00_RS19090	COG0678	peroxiredoxin activity
J5O00_RS19090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J5O00_RS19095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J5O00_RS19110	COG1278	Cold shock
J5O00_RS19120	COG4667	esterase of the alpha-beta hydrolase superfamily
J5O00_RS19130	COG1846	Transcriptional regulator
J5O00_RS19155	COG0673	inositol 2-dehydrogenase activity
J5O00_RS19160	COG2194	sulfuric ester hydrolase activity
J5O00_RS19165	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J5O00_RS19175	COG2205	protein histidine kinase activity
J5O00_RS19180	COG0745	RESPONSE REGULATOR receiver
J5O00_RS19185	COG4221	oxidoreductase activity
J5O00_RS19200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J5O00_RS19220	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5O00_RS19230	COG2814	Major facilitator Superfamily
J5O00_RS19240	COG1418	mRNA catabolic process
J5O00_RS19250	COG0402	S-adenosylhomocysteine deaminase activity
J5O00_RS19255	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J5O00_RS19260	COG2239	Acts as a magnesium transporter
J5O00_RS19265	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J5O00_RS19280	COG0531	amino acid
J5O00_RS19285	COG1522	sequence-specific DNA binding
J5O00_RS19310	COG5002	protein histidine kinase activity
J5O00_RS19310	COG2205	protein histidine kinase activity
J5O00_RS19310	COG0784	Response regulator, receiver
J5O00_RS19315	COG0673	inositol 2-dehydrogenase activity
J5O00_RS19320	COG0534	Mate efflux family protein
J5O00_RS19325	COG2926	Belongs to the UPF0265 family
J5O00_RS19335	COG3132	Protein of unknown function, DUF480
J5O00_RS19340	COG2827	Endonuclease containing a URI domain
J5O00_RS19345	COG1879	ABC-type sugar transport system periplasmic component
J5O00_RS19350	COG2205	protein histidine kinase activity
J5O00_RS19350	COG0784	Response regulator, receiver
J5O00_RS19360	COG1566	PFAM secretion protein HlyD family protein
J5O00_RS19380	COG1522	sequence-specific DNA binding
J5O00_RS19405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5O00_RS19410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5O00_RS19430	COG0183	Belongs to the thiolase family
J5O00_RS19450	COG3005	denitrification pathway
J5O00_RS19460	COG0243	molybdopterin cofactor binding
J5O00_RS19470	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J5O00_RS19475	COG3850	Histidine kinase
J5O00_RS19480	COG2197	response regulator
J5O00_RS19495	COG2195	Cleaves the N-terminal amino acid of tripeptides
J5O00_RS19515	COG0840	transmembrane signaling receptor activity
J5O00_RS19525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5O00_RS19535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J5O00_RS19540	COG2814	Major facilitator Superfamily
J5O00_RS19545	COG0840	transmembrane signaling receptor activity
J5O00_RS19550	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J5O00_RS19555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J5O00_RS19575	COG2897	thiosulfate sulfurtransferase activity
J5O00_RS19595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J5O00_RS19605	COG0302	gtp cyclohydrolase
J5O00_RS19610	COG1914	H( )-stimulated, divalent metal cation uptake system
J5O00_RS19620	COG0038	chloride channel
J5O00_RS19635	COG4989	oxidoreductase activity
J5O00_RS19650	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J5O00_RS19650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J5O00_RS19655	COG0516	GMP reductase activity
J5O00_RS19660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J5O00_RS19725	COG3474	cytochrome
J5O00_RS19735	COG0789	Transcriptional regulator
J5O00_RS19740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J5O00_RS19745	COG0384	phenazine biosynthesis protein PhzF
J5O00_RS19755	COG1294	oxidase, subunit
J5O00_RS19760	COG1271	oxidase subunit
J5O00_RS19765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5O00_RS19770	COG0110	maltose O-acetyltransferase activity
J5O00_RS19775	COG3264	Mechanosensitive ion channel
J5O00_RS19775	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J5O00_RS19790	COG2205	protein histidine kinase activity
J5O00_RS19790	COG4999	Histidine kinase
J5O00_RS19790	COG3437	response regulator, receiver
J5O00_RS19790	COG3850	Histidine kinase
J5O00_RS19800	COG4770	biotin carboxylase activity
J5O00_RS19805	COG1024	Enoyl-CoA hydratase
J5O00_RS19810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J5O00_RS19815	COG1960	acyl-CoA dehydrogenase activity
J5O00_RS19825	COG0183	Belongs to the thiolase family
J5O00_RS19835	COG1960	acyl-CoA dehydrogenase activity
J5O00_RS19840	COG1024	Enoyl-CoA hydratase
J5O00_RS19860	COG3706	GGDEF domain
J5O00_RS19865	COG1309	transcriptional regulator
J5O00_RS19870	COG1012	belongs to the aldehyde dehydrogenase family
J5O00_RS19885	COG4176	ABC-type proline glycine betaine transport system permease component
J5O00_RS19890	COG4175	Glycine betaine
J5O00_RS19890	COG0517	IMP dehydrogenase activity
J5O00_RS19905	COG0330	HflC and HflK could
J5O00_RS19915	COG5001	Diguanylate cyclase
J5O00_RS19915	COG3300	MHYT domain
J5O00_RS19925	COG2205	protein histidine kinase activity
J5O00_RS19925	COG0784	Response regulator, receiver
J5O00_RS19980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J5O00_RS19985	COG5001	Diguanylate cyclase
J5O00_RS19990	COG1869	D-ribose catabolic process
J5O00_RS19995	COG1129	ABC transporter
J5O00_RS20000	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5O00_RS20005	COG1879	ABC-type sugar transport system periplasmic component
J5O00_RS20010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5O00_RS20015	COG1609	Transcriptional regulator
J5O00_RS20030	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
J5O00_RS20050	COG0745	RESPONSE REGULATOR receiver
J5O00_RS20065	COG1785	Belongs to the alkaline phosphatase family
J5O00_RS20090	COG0814	amino acid
J5O00_RS20100	COG0243	molybdopterin cofactor binding
J5O00_RS20120	COG3707	response regulator
J5O00_RS20125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J5O00_RS20130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5O00_RS20135	COG1116	anion transmembrane transporter activity
J5O00_RS20140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J5O00_RS20140	COG2146	nitrite reductase [NAD(P)H] activity
J5O00_RS20195	COG0515	serine threonine protein kinase
J5O00_RS20195	COG2815	serine threonine protein kinase
J5O00_RS20230	COG0631	protein serine/threonine phosphatase activity
J5O00_RS20300	COG0420	3'-5' exonuclease activity
J5O00_RS20305	COG0419	ATPase involved in DNA repair
J5O00_RS20325	COG3040	lipid binding
J5O00_RS20335	COG2814	Major facilitator Superfamily
J5O00_RS20345	COG1288	antiporter activity
J5O00_RS20355	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
J5O00_RS20370	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J5O00_RS20385	COG0583	DNA-binding transcription factor activity
J5O00_RS20390	COG0277	FAD linked oxidase domain protein
J5O00_RS20405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5O00_RS20480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J5O00_RS20485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J5O00_RS20495	COG2116	formate transmembrane transporter activity
J5O00_RS20515	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J5O00_RS20545	COG0534	Mate efflux family protein
J5O00_RS20550	COG0745	RESPONSE REGULATOR receiver
J5O00_RS20550	COG2205	protein histidine kinase activity
J5O00_RS20550	COG3292	Two component regulator propeller
J5O00_RS20560	COG3118	belongs to the thioredoxin family
J5O00_RS20565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5O00_RS20590	COG2271	Major facilitator Superfamily
J5O00_RS20595	COG3851	Histidine kinase
J5O00_RS20600	COG2197	response regulator
J5O00_RS20610	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J5O00_RS20615	COG0583	DNA-binding transcription factor activity
J5O00_RS20620	COG0243	molybdopterin cofactor binding
J5O00_RS20650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5O00_RS20665	COG1328	CTP reductase activity
J5O00_RS20670	COG0602	queuosine metabolic process
J5O00_RS20675	COG0534	Mate efflux family protein
J5O00_RS20690	COG4067	protein conserved in archaea
J5O00_RS20690	COG0189	ligase activity
J5O00_RS20700	COG3111	PFAM Bacterial OB fold (BOF) protein
J5O00_RS20705	COG1492	cobalamin metabolic process
J5O00_RS20710	COG0725	ABC transporter, periplasmic molybdate-binding protein
J5O00_RS20715	COG4149	molybdate abc transporter
J5O00_RS20720	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J5O00_RS20730	COG3706	GGDEF domain
J5O00_RS20730	COG5001	Diguanylate cyclase
J5O00_RS20730	COG2203	Gaf domain
J5O00_RS20730	COG4251	negative regulation of phosphorylation
J5O00_RS20755	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J5O00_RS20760	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J5O00_RS20785	COG3140	Belongs to the UPF0181 family
J5O00_RS20790	COG0589	response to stress
J5O00_RS20840	COG4128	Pfam Zonular occludens toxin
J5O00_RS20890	COG0023	Translation Initiation Factor
J5O00_RS20900	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5O00_RS20910	COG0045	succinate-CoA ligase (ADP-forming) activity
J5O00_RS20910	COG1042	CoA-binding domain protein
J5O00_RS20910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J5O00_RS20915	COG0583	DNA-binding transcription factor activity
J5O00_RS20920	COG1629	transport
J5O00_RS20920	COG4771	TonB-dependent receptor
J5O00_RS20925	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5O00_RS20930	COG3447	MASE1 domain protein
J5O00_RS20930	COG5001	Diguanylate cyclase
J5O00_RS20930	COG5002	protein histidine kinase activity
J5O00_RS20935	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J5O00_RS20940	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J5O00_RS20945	COG1984	allophanate hydrolase subunit 2
J5O00_RS20955	COG4974	Belongs to the 'phage' integrase family
J5O00_RS21035	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J5O00_RS21040	COG4181	ATPase activity
J5O00_RS21050	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J5O00_RS21055	COG5001	Diguanylate cyclase
J5O00_RS21055	COG3300	MHYT domain
J5O00_RS21065	COG0484	heat shock protein binding
J5O00_RS21090	COG4533	DNA binding
J5O00_RS21100	COG2050	protein possibly involved in aromatic compounds catabolism
J5O00_RS21115	COG2067	long-chain fatty acid transport protein
J5O00_RS21120	COG2267	carboxylic ester hydrolase activity
J5O00_RS21135	COG0861	Integral membrane protein TerC family
J5O00_RS21140	COG0737	Belongs to the 5'-nucleotidase family
J5O00_RS21145	COG3593	DNA synthesis involved in DNA repair
J5O00_RS21155	COG0583	DNA-binding transcription factor activity
J5O00_RS21160	COG2116	formate transmembrane transporter activity
J5O00_RS21165	COG2353	YceI-like domain
J5O00_RS21170	COG3038	cytochrome b561
J5O00_RS21185	COG4943	cyclic-guanylate-specific phosphodiesterase activity
J5O00_RS21190	COG0513	Belongs to the DEAD box helicase family
J5O00_RS21195	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
J5O00_RS21205	COG0546	phosphoglycolate phosphatase activity
J5O00_RS21210	COG3437	response regulator, receiver
J5O00_RS21210	COG0784	Response regulator, receiver
J5O00_RS21225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5O00_RS21230	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J5O00_RS21235	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J5O00_RS21245	COG2207	Transcriptional regulator
J5O00_RS21250	COG1979	alcohol dehydrogenase
J5O00_RS21275	COG2271	Major facilitator Superfamily
J5O00_RS21280	COG0469	pyruvate kinase activity
J5O00_RS21285	COG1126	abc transporter atp-binding protein
J5O00_RS21290	COG0765	amino acid transport
J5O00_RS21295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5O00_RS21300	COG0765	amino acid transport
J5O00_RS21305	COG2203	Gaf domain
J5O00_RS21305	COG2199	diguanylate cyclase activity
J5O00_RS21305	COG2200	EAL domain
J5O00_RS21320	COG1609	Transcriptional regulator
J5O00_RS21325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5O00_RS21325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5O00_RS21330	COG1105	Belongs to the carbohydrate kinase PfkB family
J5O00_RS21335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J5O00_RS21335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J5O00_RS21335	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J5O00_RS21375	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5O00_RS21380	COG0509	glycine decarboxylation via glycine cleavage system
J5O00_RS21385	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5O00_RS21385	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5O00_RS21415	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J5O00_RS21420	COG0583	DNA-binding transcription factor activity
J5O00_RS21425	COG2176	DNA-directed DNA polymerase activity
J5O00_RS21465	COG0242	peptide deformylase activity
J5O00_RS21485	COG2239	Acts as a magnesium transporter
J5O00_RS21505	COG0346	lactoylglutathione lyase activity
J5O00_RS21510	COG1902	pentaerythritol trinitrate reductase activity
J5O00_RS21530	COG5642	Protein of unknown function (DUF2384)
J5O00_RS21535	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
J5O00_RS21550	COG4565	transcriptional regulatory protein
J5O00_RS21555	COG3290	protein histidine kinase activity
J5O00_RS21560	COG0471	metal ion transport
J5O00_RS21590	COG2076	Multidrug Resistance protein
J5O00_RS21605	COG0671	phosphoesterase, PA-phosphatase related
J5O00_RS21615	COG2962	Rard protein
J5O00_RS21630	COG0835	chemotaxis
J5O00_RS21630	COG0784	Response regulator, receiver
J5O00_RS21650	COG2197	response regulator
J5O00_RS21660	COG3706	GGDEF domain
J5O00_RS21665	COG2197	response regulator
J5O00_RS21670	COG3300	MHYT domain
J5O00_RS21670	COG5001	Diguanylate cyclase
J5O00_RS21690	COG0583	DNA-binding transcription factor activity
J5O00_RS21750	COG4964	Belongs to the GSP D family
J5O00_RS21775	COG2207	Transcriptional regulator
J5O00_RS21800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J5O00_RS21820	COG0456	acetyltransferase
J5O00_RS21820	COG1214	PFAM Peptidase M22, glycoprotease
J5O00_RS21830	COG3069	C4-dicarboxylate transmembrane transporter activity
J5O00_RS21835	COG1704	LemA family
J5O00_RS21840	COG0501	Belongs to the peptidase M48B family
J5O00_RS21865	COG0641	radical SAM
J5O00_RS21880	COG3111	PFAM Bacterial OB fold (BOF) protein
J5O00_RS21885	COG1597	lipid kinase activity
J5O00_RS21890	COG0583	DNA-binding transcription factor activity
J5O00_RS21895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5O00_RS21925	COG0714	Associated with various cellular activities
J5O00_RS21930	COG0641	radical SAM
J5O00_RS21935	COG3119	arylsulfatase activity
J5O00_RS21950	COG3119	arylsulfatase activity
J5O00_RS21955	COG3119	arylsulfatase activity
J5O00_RS21960	COG0745	RESPONSE REGULATOR receiver
J5O00_RS21975	COG2205	protein histidine kinase activity
J5O00_RS21975	COG2198	Histidine kinase
J5O00_RS21975	COG0784	Response regulator, receiver
J5O00_RS21980	COG1879	ABC-type sugar transport system periplasmic component
J5O00_RS21985	COG1803	Methylglyoxal synthase
J5O00_RS21990	COG0210	DNA helicase
J5O00_RS21995	COG1289	transmembrane transporter activity
J5O00_RS22025	COG1629	transport
J5O00_RS22025	COG4771	TonB-dependent receptor
J5O00_RS22030	COG2207	Transcriptional regulator
J5O00_RS22035	COG0789	Transcriptional regulator
J5O00_RS22040	COG4604	ABC transporter, ATP-binding protein
J5O00_RS22045	COG4605	iron ion homeostasis
J5O00_RS22050	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5O00_RS22055	COG4607	ABC-type enterochelin transport system periplasmic component
J5O00_RS22075	COG2847	Copper chaperone PCu(A)C
J5O00_RS22080	COG0443	Heat shock 70 kDa protein
J5O00_RS22115	COG0625	glutathione transferase activity
J5O00_RS22130	COG4160	amino acid transport
J5O00_RS22135	COG4215	(ABC) transporter
J5O00_RS22140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5O00_RS22145	COG1126	abc transporter atp-binding protein
J5O00_RS22175	COG1902	pentaerythritol trinitrate reductase activity
J5O00_RS22190	COG0109	protoheme IX farnesyltransferase activity
J5O00_RS22195	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J5O00_RS22200	COG1845	cytochrome c oxidase, subunit III
J5O00_RS22205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J5O00_RS22210	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J5O00_RS22215	COG1028	Short-chain dehydrogenase reductase Sdr
J5O00_RS22225	COG1024	Enoyl-CoA hydratase
J5O00_RS22230	COG1024	Enoyl-CoA hydratase
J5O00_RS22245	COG0183	Belongs to the thiolase family
J5O00_RS22255	COG1960	acyl-CoA dehydrogenase activity
J5O00_RS22260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J5O00_RS22265	COG1024	Enoyl-CoA hydratase
J5O00_RS22275	COG5413	integral membrane protein
J5O00_RS22290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J5O00_RS22295	COG5001	Diguanylate cyclase
J5O00_RS22300	COG0513	Belongs to the DEAD box helicase family
J5O00_RS22305	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
J5O00_RS22320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J5O00_RS22340	COG0641	radical SAM
J5O00_RS22360	COG0840	transmembrane signaling receptor activity
J5O00_RS22365	COG1119	ATPase activity
J5O00_RS22370	COG2200	EAL domain
J5O00_RS22390	COG0513	Belongs to the DEAD box helicase family
J5O00_RS22395	COG0523	cobalamin synthesis protein
J5O00_RS22405	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
J5O00_RS22415	COG0133	tryptophan synthase activity
J5O00_RS22420	COG4628	conserved protein (DUF2132)
J5O00_RS22425	COG0513	Belongs to the DEAD box helicase family
J5O00_RS22430	COG3530	Putative quorum-sensing-regulated virulence factor
J5O00_RS22450	COG2154	pterin-4-alpha-carbinolamine dehydratase
J5O00_RS22455	COG3186	Phenylalanine-4-hydroxylase
J5O00_RS22460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J5O00_RS22465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J5O00_RS22505	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
J5O00_RS22510	COG1454	alcohol dehydrogenase
J5O00_RS22515	COG2133	pyrroloquinoline quinone binding
J5O00_RS22525	COG0783	Belongs to the Dps family
J5O00_RS22530	COG0840	transmembrane signaling receptor activity
J5O00_RS22540	COG0577	efflux transmembrane transporter activity
J5O00_RS22540	COG1136	(ABC) transporter
J5O00_RS22560	COG2199	diguanylate cyclase activity
J5O00_RS22570	COG3036	rescue of stalled ribosome
J5O00_RS22575	COG1278	Cold shock
J5O00_RS22605	COG0545	Peptidyl-prolyl cis-trans isomerase
J5O00_RS22610	COG0109	protoheme IX farnesyltransferase activity
J5O00_RS22615	COG1612	heme a metabolic process
J5O00_RS22640	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J5O00_RS22650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J5O00_RS22655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5O00_RS22665	COG1280	lysine exporter protein (LysE YggA)
J5O00_RS22695	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5O00_RS22700	COG0697	spore germination
J5O00_RS22715	COG2814	Major facilitator Superfamily
J5O00_RS22720	COG0583	DNA-binding transcription factor activity
J5O00_RS22725	COG5001	Diguanylate cyclase
J5O00_RS22730	COG0739	heme binding
J5O00_RS22750	COG3314	Sporulation integral membrane protein YlbJ
J5O00_RS22765	COG0814	amino acid
J5O00_RS22785	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J5O00_RS22790	COG1072	(Pantothenic acid kinase))
J5O00_RS22800	COG1063	alcohol dehydrogenase
J5O00_RS22805	COG2213	PTS system mannitol-specific
J5O00_RS22810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5O00_RS22825	COG0798	PFAM Bile acid sodium symporter
J5O00_RS22835	COG1881	PFAM PEBP family protein
J5O00_RS22845	COG2706	6-phosphogluconolactonase activity
J5O00_RS22860	COG1131	(ABC) transporter
J5O00_RS22865	COG0842	Transport permease protein
J5O00_RS22880	COG3383	formate dehydrogenase (NAD+) activity
J5O00_RS22900	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5O00_RS22930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J5O00_RS22940	COG2067	long-chain fatty acid transport protein
J5O00_RS22950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5O00_RS22960	COG1505	serine-type exopeptidase activity
J5O00_RS22965	COG0488	(ABC) transporter
J5O00_RS22970	COG0589	response to stress
J5O00_RS22975	COG2249	NAD(P)H dehydrogenase (quinone) activity
J5O00_RS22995	COG0366	Alpha amylase catalytic
J5O00_RS23005	COG4934	collagen metabolic process
J5O00_RS23020	COG0583	DNA-binding transcription factor activity
J5O00_RS23025	COG0783	Belongs to the Dps family
J5O00_RS23030	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
J5O00_RS23060	COG3940	Belongs to the glycosyl hydrolase 43 family
J5O00_RS23095	COG2211	Major facilitator Superfamily
J5O00_RS23135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5O00_RS23140	COG0784	Response regulator, receiver
J5O00_RS23140	COG0835	chemotaxis
J5O00_RS23150	COG0748	coenzyme F420 binding
J5O00_RS23155	COG3721	Heme iron utilization protein
J5O00_RS23165	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J5O00_RS23170	COG0811	peptide transport
J5O00_RS23175	COG0848	biopolymer transport protein
J5O00_RS23185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5O00_RS23190	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J5O00_RS23230	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J5O00_RS23235	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J5O00_RS23240	COG0633	Ferredoxin
J5O00_RS23240	COG3217	Mosc domain protein beta barrel domain protein
J5O00_RS23240	COG0633	Ferredoxin
J5O00_RS23240	COG3217	Mosc domain protein beta barrel domain protein
J5O00_RS23245	COG0401	homolog of Blt101
J5O00_RS23250	COG0418	dihydroorotase activity
J5O00_RS23255	COG2354	Protein conserved in bacteria
J5O00_RS23285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J5O00_RS23285	COG2207	Transcriptional regulator
J5O00_RS23290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5O00_RS23330	COG0513	Belongs to the DEAD box helicase family
J5O00_RS23340	COG0583	DNA-binding transcription factor activity
J5O00_RS23355	COG1902	pentaerythritol trinitrate reductase activity
J5O00_RS23360	COG1063	alcohol dehydrogenase
J5O00_RS23370	COG1028	Short-chain dehydrogenase reductase Sdr
J5O00_RS23380	COG3122	Protein conserved in bacteria
J5O00_RS23395	COG0583	DNA-binding transcription factor activity
J5O00_RS23400	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J5O00_RS23405	COG0252	asparaginase activity
J5O00_RS23410	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J5O00_RS23415	COG0574	Belongs to the PEP-utilizing enzyme family
J5O00_RS23415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5O00_RS23430	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J5O00_RS23450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5O00_RS23470	COG3706	GGDEF domain
J5O00_RS23490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J5O00_RS23520	COG3842	ATPase activity
J5O00_RS23560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5O00_RS23595	COG0583	DNA-binding transcription factor activity
J5O00_RS23605	COG4948	Mandelate Racemase Muconate Lactonizing
J5O00_RS23635	COG1342	Belongs to the UPF0251 family
J5O00_RS23640	COG3015	lipoprotein NlpE involved in copper resistance
J5O00_RS23645	COG3713	MltA-interacting MipA family protein
J5O00_RS23660	COG0583	DNA-binding transcription factor activity
J5O00_RS23680	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J5O00_RS23690	COG1335	isochorismatase
J5O00_RS23700	COG0753	catalase activity
J5O00_RS23710	COG1349	DNA-binding transcription factor activity
J5O00_RS23715	COG0346	lactoylglutathione lyase activity
J5O00_RS23730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J5O00_RS23735	COG3537	Alpha-1,2-mannosidase
J5O00_RS23740	COG3537	Alpha-1,2-mannosidase
J5O00_RS23750	COG3537	Alpha-1,2-mannosidase
J5O00_RS23755	COG3537	Alpha-1,2-mannosidase
J5O00_RS23765	COG0737	Belongs to the 5'-nucleotidase family
J5O00_RS23775	COG1309	transcriptional regulator
J5O00_RS23795	COG1280	lysine exporter protein (LysE YggA)
J5O00_RS23810	COG0459	protein refolding
J5O00_RS23815	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J5O00_RS23820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J5O00_RS23845	COG1304	FMN binding
J5O00_RS23865	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J5O00_RS23870	COG1256	bacterial-type flagellum assembly
J5O00_RS23870	COG4786	Flagellar basal body rod
J5O00_RS23880	COG1706	bacterial-type flagellum-dependent cell motility
J5O00_RS23885	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J5O00_RS23890	COG4786	Flagellar basal body rod
J5O00_RS23895	COG4787	bacterial-type flagellum-dependent cell motility
J5O00_RS23900	COG1749	Flagellar hook protein flgE
J5O00_RS23905	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J5O00_RS23910	COG1558	bacterial-type flagellum-dependent cell motility
J5O00_RS23915	COG1815	bacterial-type flagellum-dependent cell motility
J5O00_RS23935	COG0741	lytic transglycosylase activity
J5O00_RS23940	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J5O00_RS23960	COG1760	l-serine dehydratase
J5O00_RS23965	COG3104	oligopeptide transport
J5O00_RS23985	COG0583	DNA-binding transcription factor activity
J5O00_RS23995	COG2866	Carboxypeptidase
J5O00_RS24000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5O00_RS24005	COG2990	Protein conserved in bacteria
J5O00_RS24030	COG3842	ATPase activity
J5O00_RS24040	COG1840	ABC-type Fe3 transport system, periplasmic component
J5O00_RS24045	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J5O00_RS24050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J5O00_RS24055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5O00_RS24060	COG1609	Transcriptional regulator
J5O00_RS24090	COG3240	lipase activity
J5O00_RS24100	COG1136	(ABC) transporter
J5O00_RS24100	COG0577	efflux transmembrane transporter activity
J5O00_RS24105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5O00_RS24110	COG2067	long-chain fatty acid transport protein
J5O00_RS24120	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J5O00_RS24135	COG1011	Hydrolase
J5O00_RS24175	COG0110	maltose O-acetyltransferase activity
J5O00_RS24180	COG1765	OsmC-like protein
J5O00_RS24185	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5O00_RS24185	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5O00_RS24200	COG3046	protein related to deoxyribodipyrimidine photolyase
J5O00_RS24205	COG0415	Belongs to the DNA photolyase family
J5O00_RS24210	COG3706	GGDEF domain
J5O00_RS24225	COG0840	transmembrane signaling receptor activity
J5O00_RS24230	COG3706	GGDEF domain
J5O00_RS24245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J5O00_RS24260	COG3033	Beta-eliminating lyase
J5O00_RS24270	COG0579	oxidoreductase
J5O00_RS24285	COG1114	Component of the transport system for branched-chain amino acids
J5O00_RS24290	COG2199	diguanylate cyclase activity
J5O00_RS24330	COG0583	DNA-binding transcription factor activity
J5O00_RS24335	COG0189	ligase activity
J5O00_RS24340	COG0189	ligase activity
J5O00_RS24340	COG4067	protein conserved in archaea
J5O00_RS24350	COG1166	arginine decarboxylase activity
J5O00_RS24355	COG0010	Belongs to the arginase family
J5O00_RS24360	COG2814	Major facilitator Superfamily
J5O00_RS24365	COG1770	oligopeptidase
J5O00_RS24380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5O00_RS24385	COG1121	(ABC) transporter
J5O00_RS24390	COG0803	Belongs to the bacterial solute-binding protein 9 family
J5O00_RS24430	COG0848	biopolymer transport protein
J5O00_RS24435	COG0811	peptide transport
J5O00_RS24440	COG0811	peptide transport
J5O00_RS24460	COG0745	RESPONSE REGULATOR receiver
J5O00_RS24465	COG0039	L-malate dehydrogenase activity
J5O00_RS24470	COG0584	glycerophosphoryl diester phosphodiesterase
J5O00_RS24480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5O00_RS24535	COG1901	pseudouridine methyltransferase
J5O00_RS24540	COG0312	modulator of DNA gyrase
J5O00_RS24545	COG0312	modulator of DNA gyrase
J5O00_RS24550	COG0351	phosphomethylpyrimidine kinase
J5O00_RS24555	COG1116	anion transmembrane transporter activity
J5O00_RS24560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5O00_RS24565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J5O00_RS24570	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J5O00_RS24575	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J5O00_RS24580	COG0352	thiamine-phosphate diphosphorylase activity
J5O00_RS24590	COG0243	molybdopterin cofactor binding
J5O00_RS24600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5O00_RS24880	COG1192	Involved in chromosome partitioning
J5O00_RS24905	COG5268	conjugation
J5O00_RS24920	COG4962	Type ii secretion system protein e
J5O00_RS24950	COG2948	multi-organism process
J5O00_RS25070	COG0739	heme binding
J5O00_RS25085	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J5O00_RS25120	COG4932	domain protein
J5O00_RS25120	COG5492	domain, Protein
J5O00_RS25160	COG2337	Toxic component of a toxin-antitoxin (TA) module
J5O00_RS25225	COG2885	chlorophyll binding
J5O00_RS25285	COG5492	domain, Protein
J5O00_RS25285	COG4932	domain protein
J5O00_RS25295	COG5492	domain, Protein
J5O00_RS25295	COG4932	domain protein
J5O00_RS25370	COG5268	conjugation
J5O00_RS25415	COG3504	Conjugal transfer protein
J5O00_RS25705	COG3501	Rhs element vgr protein
J5O00_RS25710	COG3501	Rhs element vgr protein
J5O00_RS25720	COG3501	Rhs element vgr protein
J5O00_RS25730	COG3501	Rhs element vgr protein
J5O00_RS25735	COG3501	Rhs element vgr protein
J5O00_RS25810	COG0464	growth
J5O00_RS25860	COG0438	transferase activity, transferring glycosyl groups
J5O00_RS25880	COG0582	viral genome integration into host DNA
J5O00_RS26330	COG2197	response regulator
J5O00_RS26560	COG2211	Major facilitator Superfamily
J5O00_RS26585	COG0561	phosphatase activity
J5O00_RS26595	COG0561	phosphatase activity
J5O00_RS26600	COG2160	L-arabinose isomerase activity
J5O00_RS26605	COG2160	L-arabinose isomerase activity
J5O00_RS26610	COG2160	L-arabinose isomerase activity
J5O00_RS26615	COG2160	L-arabinose isomerase activity
J5O00_RS26625	COG1069	ribulokinase activity
J5O00_RS26630	COG1069	ribulokinase activity
J5O00_RS26635	COG1069	ribulokinase activity
J5O00_RS26640	COG1069	ribulokinase activity
J5O00_RS26705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J5O00_RS26730	COG4227	nucleotidyltransferase activity
J5O00_RS26775	COG3451	type IV secretory pathway VirB4
J5O00_RS26780	COG3451	type IV secretory pathway VirB4
J5O00_RS26785	COG3451	type IV secretory pathway VirB4
J5O00_RS26790	COG3451	type IV secretory pathway VirB4
J5O00_RS26800	COG3504	Conjugal transfer protein
J5O00_RS26890	COG3451	type IV secretory pathway VirB4
J5O00_RS26895	COG3451	type IV secretory pathway VirB4
J5O00_RS26915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB