locus-tag	class	description
GPY46_RS00025	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GPY46_RS00045	ENOG4105HDD	phospholipase
GPY46_RS00075	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GPY46_RS00080	ENOG4105CR8	Transcriptional regulator
GPY46_RS00090	ENOG4105C5W	Aldolase
GPY46_RS00115	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPY46_RS00120	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GPY46_RS00125	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GPY46_RS00145	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GPY46_RS00165	ENOG4105DM4	PTS System
GPY46_RS00170	ENOG4105DE4	1-phosphofructokinase
GPY46_RS00175	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
GPY46_RS00180	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
GPY46_RS00200	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
GPY46_RS00205	ENOG4105DRP	amino acid AbC transporter
GPY46_RS00210	ENOG4106TNF	Periplasmic binding protein
GPY46_RS00215	ENOG4105E5Q	amino acid AbC transporter
GPY46_RS00220	ENOG4105CDA	abc transporter atp-binding protein
GPY46_RS00225	ENOG4105CA9	Pyruvate kinase
GPY46_RS00230	ENOG4105CXY	transporter
GPY46_RS00235	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
GPY46_RS00245	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
GPY46_RS00255	ENOG4108I6A	alcohol dehydrogenase
GPY46_RS00260	ENOG4105CF7	AraC family transcriptional regulator
GPY46_RS00275	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GPY46_RS00280	ENOG4105CKU	formyltetrahydrofolate synthetase
GPY46_RS00285	ENOG4107RE1	Inosine-guanosine kinase
GPY46_RS00305	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GPY46_RS00315	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GPY46_RS00330	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
GPY46_RS00335	ENOG4105C1J	atp-dependent rna helicase
GPY46_RS00340	ENOG4108M8H	domain protein
GPY46_RS00355	ENOG4105DS1	cytochrome b561
GPY46_RS00360	ENOG4108YYC	ycei family
GPY46_RS00365	ENOG4105TMB	Formate nitrite transporter
GPY46_RS00370	ENOG4105DUM	transcriptional regulator, lysR family
GPY46_RS00375	ENOG4108UQ5	membrane protein YcdZ
GPY46_RS00380	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
GPY46_RS00385	ENOG4105CGH	5'-nucleotidase
GPY46_RS00390	ENOG4105DU1	integral membrane protein, terc
GPY46_RS00405	ENOG4108M0H	Extracellular lipase
GPY46_RS00410	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GPY46_RS00425	ENOG4105KA0	thioesterase Superfamily protein
GPY46_RS00435	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
GPY46_RS00460	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GPY46_RS00470	ENOG4105BZU	Histidine kinase
GPY46_RS00475	ENOG4105RKW	reductase (By
GPY46_RS00485	ENOG4108I0Y	(ABC) transporter
GPY46_RS00490	ENOG4105CV6	ABC transporter, permease
GPY46_RS00500	ENOG4107R7A	Allophanate hydrolase subunit 2
GPY46_RS00505	ENOG4105P4J	Allophanate hydrolase, subunit 1
GPY46_RS00510	ENOG4105E7W	lamb ycsf family protein
GPY46_RS00515	ENOG4105BZU	Histidine kinase
GPY46_RS00520	ENOG4105CMR	udp-glucose 4-epimerase
GPY46_RS00535	ENOG4105CWB	LysR family transcriptional Regulator
GPY46_RS00540	ENOG4105CD5	CoA-binding domain protein
GPY46_RS00550	ENOG4105CPF	Cell wall formation (By similarity)
GPY46_RS00560	ENOG4108ZJT	translation initiation factor, Sui1
GPY46_RS00705	ENOG4105VZ1	Replication Protein
GPY46_RS00750	ENOG4105DHQ	Histidine kinase
GPY46_RS00860	ENOG4105VZ1	Replication Protein
GPY46_RS00895	ENOG4105EJC	lysr family transcriptional regulator
GPY46_RS00905	ENOG4108M6U	Universal stress protein A
GPY46_RS00935	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GPY46_RS00940	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GPY46_RS00955	ENOG4105BZU	Histidine kinase
GPY46_RS00975	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
GPY46_RS00980	ENOG4105E0C	molybdate abc transporter
GPY46_RS00985	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
GPY46_RS00990	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GPY46_RS00995	ENOG4105WXI	Bacterial OB fold (BOF) protein
GPY46_RS01005	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY46_RS01010	ENOG4105CGF	Aromatic amino acid aminotransferase
GPY46_RS01015	ENOG4105ECQ	AraC Family Transcriptional Regulator
GPY46_RS01025	ENOG4107QI1	Mate efflux family protein
GPY46_RS01030	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
GPY46_RS01035	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GPY46_RS01050	ENOG4105BZS	acriflavin resistance protein
GPY46_RS01080	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
GPY46_RS01090	ENOG4105C5Q	Transcriptional regulator
GPY46_RS01095	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GPY46_RS01100	ENOG4105CXY	transporter
GPY46_RS01105	ENOG4108KX4	response regulator
GPY46_RS01110	ENOG4105BZU	Histidine kinase
GPY46_RS01115	ENOG4105CXY	transporter
GPY46_RS01120	ENOG4105EIP	mannose-6-phosphate isomerase
GPY46_RS01140	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GPY46_RS01145	ENOG4105K63	Thioredoxin
GPY46_RS01150	ENOG4108ISG	Major Facilitator
GPY46_RS01160	ENOG4107QI1	Mate efflux family protein
GPY46_RS01165	ENOG4105VXR	cytoplasmic protein
GPY46_RS01190	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GPY46_RS01205	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GPY46_RS01210	ENOG4105TMB	Formate nitrite transporter
GPY46_RS01215	ENOG4105WZK	nitrite reductase NADPH small subunit
GPY46_RS01220	ENOG4107QZF	nitrite reductase NADPH large subunit
GPY46_RS01225	ENOG4105NXH	GreA GreB family elongation factor
GPY46_RS01265	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GPY46_RS01305	ENOG4108NVR	Methyl-accepting chemotaxis
GPY46_RS01310	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GPY46_RS01330	ENOG4105CXG	d-lactate dehydrogenase
GPY46_RS01335	ENOG4105CC0	LysR family Transcriptional regulator
GPY46_RS01355	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
GPY46_RS01360	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
GPY46_RS01370	ENOG4105C5W	Aldolase
GPY46_RS01385	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
GPY46_RS01395	ENOG4105C2C	drug resistance transporter, Bcr CflA
GPY46_RS01405	ENOG4105QNF	Outer membrane lipoprotein
GPY46_RS01425	ENOG4105EYH	Exonuclease
GPY46_RS01430	ENOG4107RFY	SbcCD D subunit
GPY46_RS01455	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GPY46_RS01500	ENOG4108ZF3	Phosphatase
GPY46_RS01515	ENOG4106VK6	Flagellar motor protein
GPY46_RS01535	ENOG4105D9P	serine threonine protein kinase
GPY46_RS01560	ENOG4105F8J	Adenylate Guanylate cyclase
GPY46_RS01575	ENOG4108IG5	Transcriptional regulator
GPY46_RS01590	ENOG4107QZF	nitrite reductase NADPH large subunit
GPY46_RS01595	ENOG4105D7T	ABC transporter
GPY46_RS01600	ENOG4105DG7	nitrate ABC transporter
GPY46_RS01635	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GPY46_RS01645	ENOG4108R6G	acetyltransferase
GPY46_RS01650	ENOG4105C44	Serine transporter
GPY46_RS01660	ENOG4105BZU	Histidine kinase
GPY46_RS01680	ENOG4105G6Z	alkaline phosphatase
GPY46_RS01695	ENOG4105ETX	regulatoR
GPY46_RS01725	ENOG4106E5D	Protein of unknown function (DUF461)
GPY46_RS01730	ENOG4105R8A	Heat shock protein
GPY46_RS01745	ENOG4107RUY	(E1 component), alpha subunit
GPY46_RS01750	ENOG4105CPP	Dehydrogenase, E1 component
GPY46_RS01755	ENOG4107QSN	dihydrolipoamide acetyltransferase
GPY46_RS01760	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GPY46_RS01765	ENOG4107MKT	Stringent starvation protein a
GPY46_RS01770	ENOG4105DUM	transcriptional regulator, lysR family
GPY46_RS01780	ENOG4105DMR	ABC, transporter
GPY46_RS01785	ENOG4105GBT	ABC transporter
GPY46_RS01790	ENOG4106PMH	Extracellular solute-binding protein family 3
GPY46_RS01795	ENOG4105E5Z	arginine transporter ATP-binding subunit
GPY46_RS01815	ENOG4107Y60	(LipO)protein
GPY46_RS01840	ENOG4105C26	Dehydrogenase
GPY46_RS01860	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GPY46_RS01875	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GPY46_RS01885	ENOG4105CCU	oxidase (Subunit III)
GPY46_RS01890	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GPY46_RS01895	ENOG4105E2S	oxidase) subunit II
GPY46_RS01900	ENOG4105CHR	reductase
GPY46_RS01905	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GPY46_RS01910	ENOG4105E39	Enoyl-CoA hydratase
GPY46_RS01925	ENOG4105C26	Dehydrogenase
GPY46_RS01930	ENOG4105CHU	acetyl-coa acetyltransferase
GPY46_RS01940	ENOG4105C1G	acyl-Coa dehydrogenase
GPY46_RS01945	ENOG4107QX3	carboxylase
GPY46_RS01950	ENOG4105CGU	Enoyl-CoA hydratase
GPY46_RS01955	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
GPY46_RS01970	ENOG4107SDU	Methyl-accepting chemotaxis
GPY46_RS01975	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GPY46_RS01985	ENOG4105BZU	Histidine kinase
GPY46_RS01990	ENOG4105C1J	atp-dependent rna helicase
GPY46_RS01995	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
GPY46_RS02010	ENOG4107S17	Phosphate-binding protein
GPY46_RS02025	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
GPY46_RS02085	ENOG4105C4X	radical SAM domain protein
GPY46_RS02090	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
GPY46_RS02110	ENOG4108N3W	hemolysin secretion protein
GPY46_RS02115	ENOG4105DKW	ABC transporter
GPY46_RS02120	ENOG4105CXC	rtn protein
GPY46_RS02140	ENOG4105C1J	atp-dependent rna helicase
GPY46_RS02145	ENOG4105CKI	cobalamin synthesis protein
GPY46_RS02155	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
GPY46_RS02165	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GPY46_RS02170	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GPY46_RS02175	ENOG4105C1J	atp-dependent rna helicase
GPY46_RS02180	ENOG4105VRT	cytoplasmic protein
GPY46_RS02205	ENOG41090A4	Pterin carbinolamine dehydratase
GPY46_RS02210	ENOG4105MIR	Phenylalanine 4-monooxygenase
GPY46_RS02215	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GPY46_RS02220	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GPY46_RS02260	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
GPY46_RS02265	ENOG4105C0A	alcohol dehydrogenase
GPY46_RS02280	ENOG4108RMU	ferritin dps family protein
GPY46_RS02285	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY46_RS02295	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GPY46_RS02315	ENOG4105BZU	Histidine kinase
GPY46_RS02325	ENOG4107SDU	Methyl-accepting chemotaxis
GPY46_RS02335	ENOG4105VEQ	Cold shock protein
GPY46_RS02370	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GPY46_RS02375	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GPY46_RS02380	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
GPY46_RS02400	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
GPY46_RS02405	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
GPY46_RS02460	ENOG4105FCK	Membrane
GPY46_RS02465	ENOG4108SXK	Transporter Drug Metabolite Exporter family
GPY46_RS02470	ENOG4105VW4	glutaredoxin 3
GPY46_RS02490	ENOG4105E5M	Multidrug resistance protein D
GPY46_RS02495	ENOG4105CR8	Transcriptional regulator
GPY46_RS02505	ENOG4105DR5	peptidase
GPY46_RS02530	ENOG4105DWD	nucleoside recognition domain protein
GPY46_RS02535	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY46_RS02545	ENOG4105E0U	tyrosine-specific transport protein
GPY46_RS02570	ENOG4107Z1W	Fructose transport system kinase
GPY46_RS02580	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
GPY46_RS02585	ENOG4105CTS	PTS system mannitol-specific
GPY46_RS02590	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
GPY46_RS02610	ENOG4105D6J	arsenicaL-resistance protein
GPY46_RS02620	ENOG4108V1U	phospholipid-binding protein
GPY46_RS02625	ENOG4105JAB	phenazine biosynthesis protein, phzf family
GPY46_RS02630	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
GPY46_RS02635	ENOG4108NVR	Methyl-accepting chemotaxis
GPY46_RS02645	ENOG4105CJ1	ABC, transporter
GPY46_RS02650	ENOG4107QWP	ABC-2 type transporter
GPY46_RS02665	ENOG4108IEG	Formate dehydrogenase Alpha subunit
GPY46_RS02690	ENOG4108IJF	Heavy metal efflux pump, CzcA
GPY46_RS02710	ENOG410620I	Diguanylate cyclase
GPY46_RS02720	ENOG4108HK0	-acetyltransferase
GPY46_RS02730	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GPY46_RS02740	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
GPY46_RS02755	ENOG4105C5H	ABC transporter
GPY46_RS02760	ENOG4108M6U	Universal stress protein A
GPY46_RS02765	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GPY46_RS02770	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GPY46_RS02795	ENOG4105KXC	Collagenase
GPY46_RS02810	ENOG4105C5Q	Transcriptional regulator
GPY46_RS02825	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
GPY46_RS02850	ENOG4108K2B	transcriptional regulator
GPY46_RS02855	ENOG4105F8D	glycoside hydrolase family 4
GPY46_RS02860	ENOG4105CT4	transporter
GPY46_RS02880	ENOG4105C79	DNA protecting protein DprA
GPY46_RS02905	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
GPY46_RS02915	ENOG4107R88	Chemotaxis protein (CheV)
GPY46_RS02925	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
GPY46_RS02930	ENOG41090JE	Utilization Protein
GPY46_RS02935	ENOG4105D4P	Coproporphyrinogen iii oxidase
GPY46_RS02940	ENOG4105WQ5	TonB family
GPY46_RS02945	ENOG41090AP	transport protein
GPY46_RS02950	ENOG4106GFD	transport protein
GPY46_RS02960	ENOG4105EHG	Permease protein
GPY46_RS02965	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GPY46_RS03005	ENOG4107X4V	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GPY46_RS03010	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
GPY46_RS03015	ENOG4105QVC	MOSC domain-containing protein
GPY46_RS03015	ENOG4105QVC	MOSC domain-containing protein
GPY46_RS03035	ENOG4105EKE	dihydroorotase
GPY46_RS03040	ENOG4105CKW	Inner membrane protein yedI
GPY46_RS03070	ENOG4105EG2	ABC transporter, permease
GPY46_RS03075	ENOG4105D56	permease protein
GPY46_RS03080	ENOG4107FKK	extracellular solute-binding protein family 1
GPY46_RS03085	ENOG4108IJ9	(ABC) transporter
GPY46_RS03105	ENOG4105D75	Capsular exopolysaccharide family
GPY46_RS03115	ENOG4105CPK	Glycosyl transferase (Group 1
GPY46_RS03145	ENOG4105V0I	UPF0267 protein
GPY46_RS03150	ENOG4108WUH	Transcriptional regulator, TetR family
GPY46_RS03155	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
GPY46_RS03160	ENOG4108RXX	maleylacetoacetate isomerase
GPY46_RS03165	ENOG4105CH6	catalase
GPY46_RS03170	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GPY46_RS03175	ENOG4105DM4	PTS System
GPY46_RS03180	ENOG4108YRF	PTS System
GPY46_RS03190	ENOG4106R3P	AraC family transcriptional regulator
GPY46_RS03195	ENOG4105DM4	PTS System
GPY46_RS03200	ENOG4105EIP	mannose-6-phosphate isomerase
GPY46_RS03210	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
GPY46_RS03220	ENOG4105BZU	Histidine kinase
GPY46_RS03225	ENOG4105CZN	Potassium uptake protein
GPY46_RS03240	ENOG4105BZU	Histidine kinase
GPY46_RS03245	ENOG4105BZ1	(ABC) transporter
GPY46_RS03250	ENOG4105E0K	tonB-dependent siderophore receptor
GPY46_RS03255	ENOG4105E0A	ABC, transporter
GPY46_RS03265	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
GPY46_RS03275	ENOG4105UYK	outer membrane protein a
GPY46_RS03295	ENOG4108JJ6	Type I secretion system ATPase
GPY46_RS03305	ENOG41086KC	Transcriptional regulator
GPY46_RS03310	ENOG41086KC	Transcriptional regulator
GPY46_RS03320	ENOG41069D7	Methyl-accepting chemotaxis
GPY46_RS03330	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GPY46_RS03365	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GPY46_RS03370	ENOG4105E2Z	phosphate ABC transporter (Permease
GPY46_RS03375	ENOG4105C8U	phosphate abc transporter
GPY46_RS03380	ENOG4107S17	Phosphate-binding protein
GPY46_RS03385	ENOG4108NVR	Methyl-accepting chemotaxis
GPY46_RS03405	ENOG4105D05	Receptor
GPY46_RS03410	ENOG4105CUG	Oligopeptidase b
GPY46_RS03415	ENOG4105C1J	atp-dependent rna helicase
GPY46_RS03425	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
GPY46_RS03430	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GPY46_RS03435	ENOG4108XDN	Transcriptional regulator
GPY46_RS03440	ENOG4107SEY	Conserved Protein
GPY46_RS03450	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GPY46_RS03465	ENOG4106TD9	Diguanylate cyclase
GPY46_RS03470	ENOG4105KK7	inner membrane protein YiaW
GPY46_RS03475	ENOG4105EFX	secretion protein, HlyD family
GPY46_RS03480	ENOG4108V7D	UPF0397 protein
GPY46_RS03485	ENOG4108JJB	ABC transporter
GPY46_RS03500	ENOG4105GXZ	Ferredoxin-type protein NapH
GPY46_RS03505	ENOG4108BGM	Quinol dehydrogenase periplasmic component
GPY46_RS03510	ENOG4105WCN	acetyltransferase
GPY46_RS03530	ENOG4105YE1	PilZ domain
GPY46_RS03535	ENOG4108NVR	Methyl-accepting chemotaxis
GPY46_RS03540	ENOG4105DAN	ATP-dependent protease
GPY46_RS03550	ENOG4108JQ5	ABC transporter
GPY46_RS03560	ENOG4105CR8	Transcriptional regulator
GPY46_RS03565	ENOG4105DAA	L-lactate
GPY46_RS03570	ENOG4105DMF	Dehydrogenase
GPY46_RS03580	ENOG4105D64	Mechanosensitive ion channel
GPY46_RS03620	ENOG4105CPQ	Dehydrogenase
GPY46_RS03625	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GPY46_RS03630	ENOG4105BZU	Histidine kinase
GPY46_RS03635	ENOG4107R0W	ABC transporter
GPY46_RS03645	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GPY46_RS03655	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GPY46_RS03685	ENOG4105EXG	Transcriptional regulator
GPY46_RS03690	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
GPY46_RS03710	ENOG4107SSZ	Phosphatase
GPY46_RS03740	ENOG4108JIR	Flagellum-specific ATP synthase
GPY46_RS03750	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GPY46_RS03755	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GPY46_RS03765	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY46_RS03780	ENOG4105DD5	Flagellar motor switch protein
GPY46_RS03785	ENOG4105CN7	Flagellar biosynthetic protein FliP
GPY46_RS03790	ENOG4105VS8	Flagellar biosynthetic protein fliq
GPY46_RS03795	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GPY46_RS03800	ENOG4105D00	flagellar biosynthetic protein flhB
GPY46_RS03815	ENOG4105I03	Flagellin
GPY46_RS03825	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
GPY46_RS03830	ENOG4105MQ3	flagellar protein FliS
GPY46_RS03855	ENOG4107RD7	Flagellar Motor Protein, MotA
GPY46_RS03860	ENOG4105ER2	Ompa motb domain protein
GPY46_RS03870	ENOG4105KWG	Pfam:DUF1696
GPY46_RS03910	ENOG4105C6N	Formate acetyltransferase
GPY46_RS03915	ENOG4105F1A	Pyruvate formate-lyase
GPY46_RS03920	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GPY46_RS03930	ENOG4105I4A	GCN5-related N-acetyltransferase
GPY46_RS03945	ENOG4105CNH	Multidrug resistance protein MdtL
GPY46_RS03950	ENOG4105G2Y	Transcriptional regulator
GPY46_RS03990	ENOG4105IPI	Membrane
GPY46_RS03995	ENOG41068P6	UPF0319 protein
GPY46_RS04005	ENOG4105DP0	ferredoxin-NADP reductase
GPY46_RS04015	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
GPY46_RS04020	ENOG4105ETT	transcriptional Regulator, LysR family
GPY46_RS04030	ENOG4108RCM	Nitroreductase
GPY46_RS04035	ENOG4108ZX5	transcriptional regulator
GPY46_RS04045	ENOG4105DZ1	carboxypeptidase
GPY46_RS04060	ENOG4105C72	UPF0176 protein
GPY46_RS04065	ENOG4108M1A	Chitin-binding protein
GPY46_RS04070	ENOG4108NRW	Phospholipase, patatin family
GPY46_RS04075	ENOG41081FY	multiple antibiotic resistance (MarC)-related
GPY46_RS04090	ENOG4105DAY	polysaccharide export protein
GPY46_RS04095	ENOG4107ZF2	Phosphatase
GPY46_RS04110	ENOG4105N0V	mono-oxygenase ydhR
GPY46_RS04115	ENOG4105F04	LysR family Transcriptional regulator
GPY46_RS04125	ENOG4105CK2	sodium dicarboxylate symporter
GPY46_RS04145	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GPY46_RS04150	ENOG4108P2H	Inner membrane protein YjiG
GPY46_RS04155	ENOG41074DU	domain protein
GPY46_RS04170	ENOG4107T9C	Alpha amylase catalytic region
GPY46_RS04175	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
GPY46_RS04180	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GPY46_RS04185	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
GPY46_RS04190	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GPY46_RS04205	ENOG41061ZR	Transcriptional regulator
GPY46_RS04235	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GPY46_RS04240	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
GPY46_RS04250	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
GPY46_RS04260	ENOG4105D5Q	Arginine ornithine antiporter
GPY46_RS04265	ENOG4105CXN	decarboxylase
GPY46_RS04285	ENOG4108K8S	endonuclease I
GPY46_RS04310	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
GPY46_RS04325	ENOG4105E5M	Multidrug resistance protein D
GPY46_RS04335	ENOG4105DR5	peptidase
GPY46_RS04345	ENOG4107RAN	Peptidase, M16
GPY46_RS04355	ENOG4105E0A	ABC, transporter
GPY46_RS04360	ENOG4108U1V	ABC transporter, permease
GPY46_RS04365	ENOG4105DQ5	transport system permease protein
GPY46_RS04370	ENOG4108HUF	Transporter
GPY46_RS04375	ENOG4105GAV	receptor
GPY46_RS04380	ENOG4105E0K	tonB-dependent siderophore receptor
GPY46_RS04390	ENOG4105DUU	IucA IucC family protein
GPY46_RS04400	ENOG4105DBM	Siderophore biosynthesis protein
GPY46_RS04405	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GPY46_RS04410	ENOG4108JP0	extracellular solute-binding protein family 1
GPY46_RS04415	ENOG4105DHQ	Histidine kinase
GPY46_RS04420	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GPY46_RS04430	ENOG4105CI1	PTS System
GPY46_RS04460	ENOG4105CKK	Glycosyl transferase, family 2
GPY46_RS04480	ENOG4108ZHJ	Organic hydroperoxide resistance protein
GPY46_RS04485	ENOG4105K56	Transcriptional regulator
GPY46_RS04490	ENOG4105D3R	alkyl hydroperoxide reductase
GPY46_RS04495	ENOG4108JU3	Alkyl hydroperoxide reductase
GPY46_RS04510	ENOG4105EXG	Transcriptional regulator
GPY46_RS04520	ENOG4105ECQ	AraC Family Transcriptional Regulator
GPY46_RS04525	ENOG4108AEY	RNA polymerase sigma factor
GPY46_RS04540	ENOG4108N3W	hemolysin secretion protein
GPY46_RS04545	ENOG4105W8I	Transcriptional regulator
GPY46_RS04550	ENOG4105F8D	glycoside hydrolase family 4
GPY46_RS04565	ENOG4108RPX	mosc domain containing protein
GPY46_RS04570	ENOG4105C1J	atp-dependent rna helicase
GPY46_RS04585	ENOG4105CF7	AraC family transcriptional regulator
GPY46_RS04595	ENOG4105BZ1	(ABC) transporter
GPY46_RS04605	ENOG4105EW9	transcriptional regulator AsnC family
GPY46_RS04640	ENOG4105CK7	Sodium proline symporter
GPY46_RS04650	ENOG4105C26	Dehydrogenase
GPY46_RS04670	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GPY46_RS04675	ENOG4105CQZ	Histidine kinase
GPY46_RS04680	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY46_RS04685	ENOG4107QZV	Type I secretion membrane fusion protein
GPY46_RS04700	ENOG4108JJA	ABC, transporter
GPY46_RS04735	ENOG4108J59	Extracellular solute-binding protein, family 5
GPY46_RS04745	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
GPY46_RS04755	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPY46_RS04760	ENOG4105C5Y	PTS System
GPY46_RS04770	ENOG4105EC3	peptidase S51, dipeptidase E
GPY46_RS04790	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
GPY46_RS04795	ENOG4106RMF	ParB family
GPY46_RS04815	ENOG4108JQ7	(ABC) transporter
GPY46_RS04845	ENOG4105BZU	Histidine kinase
GPY46_RS04855	ENOG4105CDY	transcriptional regulatory protein
GPY46_RS04860	ENOG4105CNI	cell division protein FtsW
GPY46_RS04895	ENOG4108HRK	Histidine kinase
GPY46_RS04900	ENOG4108VAC	response regulator
GPY46_RS04910	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GPY46_RS04915	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY46_RS04945	ENOG4105D6U	Sodium Glutamate Symporter
GPY46_RS04955	ENOG4105DVE	abc transporter atp-binding protein
GPY46_RS04960	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GPY46_RS04965	ENOG4105D6U	Sodium Glutamate Symporter
GPY46_RS04980	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GPY46_RS05000	ENOG4105C2I	pirin domain protein
GPY46_RS05005	ENOG4108VGI	doxx family
GPY46_RS05020	ENOG4105D03	DNA-3-methyladenine glycosylase II
GPY46_RS05025	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GPY46_RS05045	ENOG4105DN9	Na H antiporter
GPY46_RS05075	ENOG4105NBK	UPF0345 protein
GPY46_RS05085	ENOG4108K0B	C-di-gmp phosphodiesterase
GPY46_RS05095	ENOG4105UQX	Mate efflux family protein
GPY46_RS05100	ENOG4105D3G	Pseudouridine synthase
GPY46_RS05115	ENOG4105EJC	lysr family transcriptional regulator
GPY46_RS05120	ENOG4108HCJ	Hydrolase
GPY46_RS05130	ENOG4108KHX	Diguanylate cyclase
GPY46_RS05140	ENOG4105C4W	S-formylglutathione hydrolase
GPY46_RS05150	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
GPY46_RS05155	ENOG4105CC0	LysR family Transcriptional regulator
GPY46_RS05170	ENOG4105J4Q	Transcriptional regulator
GPY46_RS05175	ENOG4105CHR	reductase
GPY46_RS05180	ENOG4105P66	Membrane
GPY46_RS05185	ENOG4105M5J	Cupin 2, conserved barrel domain protein
GPY46_RS05200	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
GPY46_RS05205	ENOG4108UHU	Aldolase
GPY46_RS05230	ENOG4105CAZ	oligogalacturonide lyase
GPY46_RS05235	ENOG4105Q26	Siderophore-interacting protein
GPY46_RS05245	ENOG4105EW9	transcriptional regulator AsnC family
GPY46_RS05250	ENOG4108M1A	Chitin-binding protein
GPY46_RS05265	ENOG4107W31	Pentapeptide repeat protein
GPY46_RS05270	ENOG4105EIF	outer membrane protein W
GPY46_RS05280	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GPY46_RS05300	ENOG4107WCA	isomerase
GPY46_RS05305	ENOG4108UVJ	appr-1-p processing domain protein
GPY46_RS05310	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
GPY46_RS05315	ENOG4108WAV	Transcriptional regulator
GPY46_RS05340	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
GPY46_RS05365	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
GPY46_RS05370	ENOG4105C6Z	Gluconate
GPY46_RS05375	ENOG4105BZW	Glycerate kinase
GPY46_RS05380	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GPY46_RS05415	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GPY46_RS05425	ENOG4105CUW	cytochrome C-TYPE protein
GPY46_RS05430	ENOG4107QY8	reductase
GPY46_RS05440	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GPY46_RS05445	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
GPY46_RS05450	ENOG4105ETU	transcriptional activator (TenA
GPY46_RS05455	ENOG4107Z6I	Thiamine biosynthesis protein
GPY46_RS05460	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
GPY46_RS05465	ENOG4108YI8	ABC transporter
GPY46_RS05470	ENOG4105DWF	phosphomethylpyrimidine kinase
GPY46_RS05490	ENOG4108TEM	pseudouridine methyltransferase
GPY46_RS05545	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
GPY46_RS05600	ENOG4108RU0	short-chain dehydrogenase reductase
GPY46_RS05605	ENOG4105F27	Major Facilitator
GPY46_RS05610	ENOG4105HEI	LysR family (Transcriptional regulator
GPY46_RS05630	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GPY46_RS05635	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GPY46_RS05655	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GPY46_RS05665	ENOG4108YYI	Protein of unknown function (DUF2810)
GPY46_RS05670	ENOG4105C5I	Dehydrogenase
GPY46_RS05680	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
GPY46_RS05685	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GPY46_RS05690	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GPY46_RS05695	ENOG410804D	Sensor Signal Transduction Histidine Kinase
GPY46_RS05720	ENOG4109015	Biopolymer transport protein exbD tolR
GPY46_RS05760	ENOG4105DSE	periplasmic solute binding protein
GPY46_RS05765	ENOG4105DIK	(ABC) transporter
GPY46_RS05770	ENOG4105CC5	ABC transporter
GPY46_RS05785	ENOG4105CUG	Oligopeptidase b
GPY46_RS05790	ENOG4105E5M	Multidrug resistance protein D
GPY46_RS05795	ENOG4105CYW	agmatinase
GPY46_RS05800	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GPY46_RS05810	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY46_RS05815	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY46_RS05825	ENOG4105DUM	transcriptional regulator, lysR family
GPY46_RS05860	ENOG4105CQZ	Histidine kinase
GPY46_RS05865	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY46_RS05870	ENOG4105BZU	Histidine kinase
GPY46_RS05875	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GPY46_RS05900	ENOG4105D5U	fad dependent oxidoreductase
GPY46_RS05910	ENOG4105C0F	tryptophanase EC 4.1.99.1
GPY46_RS05930	ENOG4105D9N	nucleoside
GPY46_RS05940	ENOG4105CF1	Alkylated DNA repair protein
GPY46_RS05950	ENOG4108N3W	hemolysin secretion protein
GPY46_RS05965	ENOG4106TD9	Diguanylate cyclase
GPY46_RS05970	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
GPY46_RS05975	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
GPY46_RS05990	ENOG4105E0X	reductase
GPY46_RS05995	ENOG4108UKZ	OsmC family
GPY46_RS06000	ENOG4108UW5	maltose o-acetyltransferase
GPY46_RS06035	ENOG4105JQN	Transcriptional regulator
GPY46_RS06040	ENOG4105PAD	Hydrolase
GPY46_RS06055	ENOG4108UUE	Transcriptional regulator
GPY46_RS06065	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GPY46_RS06070	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GPY46_RS06075	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GPY46_RS06085	ENOG4105KUU	lipolytic protein G-D-S-L family
GPY46_RS06090	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
GPY46_RS06115	ENOG4105ETE	Transcriptional regulator (LacI family
GPY46_RS06120	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
GPY46_RS06125	ENOG4108JPW	Aminotransferase
GPY46_RS06130	ENOG4107STF	Involved in phosphonate degradation (By similarity)
GPY46_RS06150	ENOG4107RCV	ABC transporter, permease
GPY46_RS06170	ENOG4108MJ5	VirK protein
GPY46_RS06185	ENOG4105CJP	fad dependent oxidoreductase
GPY46_RS06205	ENOG4105ETT	transcriptional Regulator, LysR family
GPY46_RS06225	ENOG4105DUX	Transporter
GPY46_RS06230	ENOG4105EJQ	L-serine dehydratase
GPY46_RS06250	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GPY46_RS06260	ENOG4105E4C	Lytic transglycosylase catalytic
GPY46_RS06280	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GPY46_RS06285	ENOG4108ZC9	flagellar basal-body rod protein flgc
GPY46_RS06290	ENOG4105W00	Flagellar hook capping protein
GPY46_RS06295	ENOG4105BZE	flagellar hook protein, FlgE
GPY46_RS06300	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GPY46_RS06305	ENOG4105CGA	flagellar basal-body rod protein FlgG
GPY46_RS06310	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GPY46_RS06315	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GPY46_RS06320	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GPY46_RS06325	ENOG4105E1Q	flagellar hook-associated protein
GPY46_RS06330	ENOG4105DTJ	flagellar hook-associated protein
GPY46_RS06350	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
GPY46_RS06380	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GPY46_RS06390	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GPY46_RS06395	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GPY46_RS06410	ENOG4105N14	lysine exporter protein LysE YggA
GPY46_RS06430	ENOG4107Z3H	Transcriptional regulator, TetR family
GPY46_RS06440	ENOG4105CGH	5'-nucleotidase
GPY46_RS06445	ENOG4105EA8	2-Nitropropane dioxygenase
GPY46_RS06450	ENOG4105CWX	Alpha-1,2-mannosidase
GPY46_RS06455	ENOG4105CWX	Alpha-1,2-mannosidase
GPY46_RS06465	ENOG4105CWX	Alpha-1,2-mannosidase
GPY46_RS06470	ENOG4105CWX	Alpha-1,2-mannosidase
GPY46_RS06475	ENOG4105DM4	PTS System
GPY46_RS06485	ENOG4105G2Y	Transcriptional regulator
GPY46_RS06495	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GPY46_RS06500	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
GPY46_RS06505	ENOG4105N2W	Transcriptional regulator
GPY46_RS06515	ENOG4105CH6	catalase
GPY46_RS06525	ENOG4108RWI	nicotinamidase
GPY46_RS06535	ENOG4107RH7	Nicotinate phosphoribosyltransferase
GPY46_RS06565	ENOG4105ETT	transcriptional Regulator, LysR family
GPY46_RS06580	ENOG4105RW8	MltA-interacting MipA family protein
GPY46_RS06590	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
GPY46_RS06600	ENOG4105VYW	UPF0251 protein
GPY46_RS06625	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GPY46_RS06635	ENOG4107S8C	mandelate racemase muconate lactonizing
GPY46_RS06645	ENOG4105RQF	LysR family Transcriptional regulator
GPY46_RS06665	ENOG4108Z4X	TRANSCRIPTIONal
GPY46_RS06695	ENOG4107RZC	phospholipase d
GPY46_RS06745	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPY46_RS06785	ENOG41086KC	Transcriptional regulator
GPY46_RS06795	ENOG4105BZU	Histidine kinase
GPY46_RS06815	ENOG4107KET	secretion protein, HlyD family
GPY46_RS06830	ENOG4107RUE	extracellular solute-binding protein family 1
GPY46_RS06835	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GPY46_RS06855	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GPY46_RS06860	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
GPY46_RS06865	ENOG4105HDK	L-asparaginase
GPY46_RS06870	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GPY46_RS06890	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
GPY46_RS06900	ENOG4108ZX5	transcriptional regulator
GPY46_RS06905	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GPY46_RS06915	ENOG4105CPQ	Dehydrogenase
GPY46_RS06920	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GPY46_RS06935	ENOG4107RSM	transcriptional regulator
GPY46_RS06945	ENOG4105C1J	atp-dependent rna helicase
GPY46_RS06990	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GPY46_RS06995	ENOG410874W	AraC family transcriptional regulator
GPY46_RS07015	ENOG4108P3C	
GPY46_RS07035	ENOG4105CHR	reductase
GPY46_RS07055	ENOG4105NAE	bifunctional deaminase-reductase domain protein
GPY46_RS07065	ENOG4105CYM	Glutathione S-transferase
GPY46_RS07075	ENOG4105DZ1	carboxypeptidase
GPY46_RS07095	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GPY46_RS07115	ENOG4105VEQ	Cold shock protein
GPY46_RS07120	ENOG4105EUB	pirin domain protein
GPY46_RS07125	ENOG4108NRW	Phospholipase, patatin family
GPY46_RS07135	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
GPY46_RS07160	ENOG4105EP9	oxidoreductase
GPY46_RS07165	ENOG4105DIJ	Phosphoethanolamine transferase
GPY46_RS07170	ENOG41080IJ	Diacylglycerol kinase
GPY46_RS07180	ENOG4105JJR	Histidine kinase
GPY46_RS07185	ENOG4107EXC	regulatoR
GPY46_RS07190	ENOG4105EMU	Dehydrogenase
GPY46_RS07210	ENOG4108Z33	Thiol disulfide Interchange Protein
GPY46_RS07230	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GPY46_RS07240	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
GPY46_RS07255	ENOG4105EST	Metal Dependent Phosphohydrolase
GPY46_RS07265	ENOG4105DZC	cytosine deaminase
GPY46_RS07270	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
GPY46_RS07280	ENOG4105CJW	magnesium transporter
GPY46_RS07285	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GPY46_RS07300	ENOG4105DVH	amino acid
GPY46_RS07310	ENOG4108XM1	transcriptional regulator AsnC family
GPY46_RS07315	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
GPY46_RS07340	ENOG4105BZU	Histidine kinase
GPY46_RS07345	ENOG4105EE0	oxidoreductase
GPY46_RS07355	ENOG41090HJ	UPF0265 protein
GPY46_RS07370	ENOG4108YXG	UPF0502 protein
GPY46_RS07375	ENOG41082IR	Excinuclease ABC C subunit domain protein
GPY46_RS07380	ENOG4108QGH	periplasmic
GPY46_RS07385	ENOG4105BZU	Histidine kinase
GPY46_RS07395	ENOG4105EFX	secretion protein, HlyD family
GPY46_RS07415	ENOG4105EW9	transcriptional regulator AsnC family
GPY46_RS07440	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPY46_RS07445	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPY46_RS07465	ENOG4105CHU	acetyl-coa acetyltransferase
GPY46_RS07475	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
GPY46_RS07485	ENOG4105CUW	cytochrome C-TYPE protein
GPY46_RS07495	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GPY46_RS07510	ENOG4105BZU	Histidine kinase
GPY46_RS07515	ENOG4105WH1	Two component transcriptional regulator luxr family
GPY46_RS07530	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GPY46_RS07535	ENOG4107YWA	deoxycytidylate deaminase
GPY46_RS07550	ENOG4108N3W	hemolysin secretion protein
GPY46_RS07555	ENOG4108YZN	class I peptide chain release factor
GPY46_RS07560	ENOG4107VXZ	Hydrolase
GPY46_RS07565	ENOG4105UYK	outer membrane protein a
GPY46_RS07570	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GPY46_RS07575	ENOG4105DXI	Major Facilitator superfamily
GPY46_RS07585	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
GPY46_RS07590	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GPY46_RS07595	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GPY46_RS07615	ENOG4105BZU	Histidine kinase
GPY46_RS07620	ENOG4105KHC	sulfurtransferase
GPY46_RS07640	ENOG4105D06	uba thif-type nad fad binding protein
GPY46_RS07645	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GPY46_RS07655	ENOG4105C5A	transporter
GPY46_RS07665	ENOG4105CMQ	Chloride channel
GPY46_RS07680	ENOG4107RGM	aldo keto reductase
GPY46_RS07685	ENOG4108UNF	response regulator
GPY46_RS07695	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GPY46_RS07700	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GPY46_RS07705	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GPY46_RS07710	ENOG4105C10	Electron transfer flavoprotein
GPY46_RS07715	ENOG4105BZJ	Electron transfer flavoprotein
GPY46_RS07720	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GPY46_RS07730	ENOG4105C0Z	ABC transporter
GPY46_RS07755	ENOG4108IV0	ABC, transporter
GPY46_RS07760	ENOG4105DZS	Phenylacetate-CoA ligase
GPY46_RS07775	ENOG4105G9V	cytochrome C
GPY46_RS07785	ENOG4105VUF	Transcriptional regulator
GPY46_RS07790	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
GPY46_RS07795	ENOG4108S58	Phenazine biosynthesis protein PhzF
GPY46_RS07805	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GPY46_RS07810	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GPY46_RS07815	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GPY46_RS07820	ENOG4108UW5	maltose o-acetyltransferase
GPY46_RS07830	ENOG4105EGS	Mechanosensitive ion channel
GPY46_RS07845	ENOG4105BZU	Histidine kinase
GPY46_RS07850	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
GPY46_RS07855	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GPY46_RS07860	ENOG4108IPT	Naphthoate synthase
GPY46_RS07865	ENOG4107QX3	carboxylase
GPY46_RS07870	ENOG4105C1G	acyl-Coa dehydrogenase
GPY46_RS07880	ENOG4105CHU	acetyl-coa acetyltransferase
GPY46_RS07885	ENOG4105C26	Dehydrogenase
GPY46_RS07890	ENOG4105C1G	acyl-Coa dehydrogenase
GPY46_RS07895	ENOG4105E39	Enoyl-CoA hydratase
GPY46_RS07905	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
GPY46_RS07910	ENOG4105CHR	reductase
GPY46_RS07920	ENOG4105BZU	Histidine kinase
GPY46_RS07925	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
GPY46_RS07930	ENOG4105C26	Dehydrogenase
GPY46_RS07935	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
GPY46_RS07945	ENOG4108HQS	Glycine betaine
GPY46_RS07950	ENOG4108IJ7	Glycine betaine
GPY46_RS07955	ENOG4108RCM	Nitroreductase
GPY46_RS07965	ENOG4107QX8	SPFH domain, Band 7 family protein
GPY46_RS07975	ENOG4105BZU	Histidine kinase
GPY46_RS07990	ENOG4105CA0	peroxidase
GPY46_RS07995	ENOG4105BZU	Histidine kinase
GPY46_RS08055	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GPY46_RS08060	ENOG4108K0B	C-di-gmp phosphodiesterase
GPY46_RS08065	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
GPY46_RS08070	ENOG4105C2J	ABC transporter
GPY46_RS08075	ENOG4105CNN	ABC, transporter
GPY46_RS08080	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GPY46_RS08085	ENOG4108RVA	ribokinase
GPY46_RS08090	ENOG4105ETE	Transcriptional regulator (LacI family
GPY46_RS08100	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
GPY46_RS08105	ENOG4108I5U	Uridine phosphorylase
GPY46_RS08120	ENOG4105DHS	permease protein
GPY46_RS08125	ENOG4105CM4	permease protein
GPY46_RS08130	ENOG4108IPW	abc transporter atp-binding protein
GPY46_RS08135	ENOG4108Z6Z	Transcriptional regulator
GPY46_RS08185	ENOG4105EM2	membrane
GPY46_RS08190	ENOG41088T4	Helicase IV
GPY46_RS08195	ENOG4108Z5K	methylglyoxal synthase
GPY46_RS08200	ENOG4108SV3	Tmao reductase system periplasmic protein tort
GPY46_RS08205	ENOG4105BZU	Histidine kinase
GPY46_RS08220	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GPY46_RS08225	ENOG4105ENH	Sulfatase
GPY46_RS08230	ENOG4105ENH	Sulfatase
GPY46_RS08245	ENOG4105ENH	Sulfatase
GPY46_RS08250	ENOG4105C4X	radical SAM domain protein
GPY46_RS08255	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GPY46_RS08285	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GPY46_RS08290	ENOG41064T2	transcriptional regulator, lysR family
GPY46_RS08295	ENOG4107TE5	Lipid kinase
GPY46_RS08300	ENOG4108YDI	single-species biofilm formation on inanimate substrate
GPY46_RS08320	ENOG4105C4X	radical SAM domain protein
GPY46_RS08330	ENOG4105F2V	VRR-NUC domain-containing protein
GPY46_RS08350	ENOG4105D0M	Protease HtpX homolog
GPY46_RS08355	ENOG4108V0P	LemA family
GPY46_RS08360	ENOG4105CEE	C4-dicarboxylate transporter
GPY46_RS08380	ENOG4108MGY	Histidine kinase
GPY46_RS08385	ENOG4107KBT	8-Amino-7-oxononanoate synthase
GPY46_RS08390	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
GPY46_RS08400	ENOG4105KXC	Collagenase
GPY46_RS08410	ENOG4106R3P	AraC family transcriptional regulator
GPY46_RS08485	ENOG4105CDV	Ompa motb domain protein
GPY46_RS08495	ENOG4108WAV	Transcriptional regulator
GPY46_RS08500	ENOG41064T2	transcriptional regulator, lysR family
GPY46_RS08510	ENOG4105BZU	Histidine kinase
GPY46_RS08515	ENOG4105BZU	Histidine kinase
GPY46_RS08520	ENOG4108WQH	regulatoR
GPY46_RS08525	ENOG4105BZU	Histidine kinase
GPY46_RS08535	ENOG4108WQH	regulatoR
GPY46_RS08560	ENOG4107R88	Chemotaxis protein (CheV)
GPY46_RS08580	ENOG4105FR1	rard protein
GPY46_RS08595	ENOG4106CKV	Pap2 superfamily protein
GPY46_RS08615	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
GPY46_RS08635	ENOG4107RGH	Aldehyde dehydrogenase
GPY46_RS08640	ENOG4107QPK	)-transporter
GPY46_RS08645	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GPY46_RS08650	ENOG4106YYS	transcriptional regulatory protein
GPY46_RS08660	ENOG4105CBC	glutamate synthase
GPY46_RS08670	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
GPY46_RS08695	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GPY46_RS08700	ENOG4108UYE	Lactoylglutathione lyase
GPY46_RS08720	ENOG4105CJW	magnesium transporter
GPY46_RS08740	ENOG4108RR8	protoporphyrinogen oxidase
GPY46_RS08745	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GPY46_RS08750	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GPY46_RS08755	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GPY46_RS08760	ENOG4105CHU	acetyl-coa acetyltransferase
GPY46_RS08765	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
GPY46_RS08780	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
GPY46_RS08795	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
GPY46_RS08800	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GPY46_RS08805	ENOG4107T9C	Alpha amylase catalytic region
GPY46_RS08810	ENOG4105JKW	Valine--pyruvate aminotransferase
GPY46_RS08815	ENOG4108ZNX	Heat shock protein
GPY46_RS08835	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPY46_RS08840	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GPY46_RS08845	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GPY46_RS08850	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GPY46_RS08865	ENOG4105EAB	amino acid AbC transporter
GPY46_RS08870	ENOG4105E5Q	amino acid AbC transporter
GPY46_RS08885	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GPY46_RS08890	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GPY46_RS08895	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPY46_RS08900	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GPY46_RS08905	ENOG4105QTB	Flavodoxin
GPY46_RS08910	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GPY46_RS08915	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GPY46_RS08920	ENOG4107QJE	Chromosome Partitioning Protein
GPY46_RS08925	ENOG4105FA0	parb-like partition protein
GPY46_RS08930	ENOG410684E	atp synthase
GPY46_RS08935	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GPY46_RS08940	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GPY46_RS08945	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GPY46_RS08950	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GPY46_RS08955	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GPY46_RS08960	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GPY46_RS08965	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GPY46_RS08970	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GPY46_RS08975	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GPY46_RS08980	ENOG4105EAD	ABC transporter
GPY46_RS08990	ENOG4105CZQ	inner membrane transport protein YdhC
GPY46_RS08995	ENOG4105F52	Transcriptional regulator
GPY46_RS09000	ENOG4105C7B	Threonine dehydratase
GPY46_RS09005	ENOG4105C01	Dihydroxy-acid dehydratase
GPY46_RS09010	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GPY46_RS09015	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
GPY46_RS09025	ENOG4105C0P	Mg chelatase subunit ChlI
GPY46_RS09035	ENOG4106HNH	Acyl-transferase
GPY46_RS09040	ENOG4108Z33	Thiol disulfide Interchange Protein
GPY46_RS09045	ENOG4105E27	serine threonine protein kinase
GPY46_RS09055	ENOG4105PC1	Conserved Protein
GPY46_RS09065	ENOG4108N23	SpoOM-related protein
GPY46_RS09070	ENOG4108UT2	hemolysin iii
GPY46_RS09080	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GPY46_RS09085	ENOG4105C1A	potassium transporter peripheral membrane
GPY46_RS09090	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GPY46_RS09095	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GPY46_RS09100	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GPY46_RS09110	ENOG4105C79	DNA protecting protein DprA
GPY46_RS09115	ENOG4108RPN	Protein smg homolog
GPY46_RS09120	ENOG4108WI1	Dna topoisomerase
GPY46_RS09125	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GPY46_RS09130	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GPY46_RS09135	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GPY46_RS09140	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GPY46_RS09145	ENOG4105E2X	shikimate dehydrogenase
GPY46_RS09150	ENOG4105SG3	Protein of unknown function (DUF1488)
GPY46_RS09155	ENOG4108Z0R	Transferase
GPY46_RS09195	ENOG4105EMY	transcriptional regulator
GPY46_RS09200	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GPY46_RS09205	ENOG4105W0Z	cytoplasmic protein
GPY46_RS09215	ENOG4105BZS	acriflavin resistance protein
GPY46_RS09220	ENOG410624X	efflux transporter, rnd family, mfp subunit
GPY46_RS09225	ENOG41067SE	Tetr family transcriptional regulator
GPY46_RS09230	ENOG4105C4R	Atp-dependent dna helicase
GPY46_RS09235	ENOG4105MPD	Cytochrome
GPY46_RS09285	ENOG4108JQ6	ABC transporter
GPY46_RS09290	ENOG4105DEF	Extracellular solute-binding protein, family 5
GPY46_RS09295	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GPY46_RS09300	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPY46_RS09335	ENOG4105D9P	serine threonine protein kinase
GPY46_RS09340	ENOG4105DIQ	Transcriptional regulator
GPY46_RS09345	ENOG41064T2	transcriptional regulator, lysR family
GPY46_RS09350	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
GPY46_RS09355	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
GPY46_RS09360	ENOG4105C01	Dihydroxy-acid dehydratase
GPY46_RS09365	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GPY46_RS09370	ENOG4105C6Z	Gluconate
GPY46_RS09375	ENOG4108UHU	Aldolase
GPY46_RS09380	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
GPY46_RS09385	ENOG4107RSM	transcriptional regulator
GPY46_RS09390	ENOG4105DC8	reductase
GPY46_RS09395	ENOG4105D6S	protein involved in catabolism of external DNA
GPY46_RS09400	ENOG4105DGW	oligopeptidase A
GPY46_RS09405	ENOG4108VVK	transcriptional Regulator, AsnC
GPY46_RS09410	ENOG4105BZU	Histidine kinase
GPY46_RS09415	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
GPY46_RS09425	ENOG4105EMK	carboxylate amino acid amine transporter
GPY46_RS09430	ENOG4108M6U	Universal stress protein A
GPY46_RS09435	ENOG41090A1	ferritin
GPY46_RS09440	ENOG4108V6B	universal stress protein B
GPY46_RS09445	ENOG4105CBX	hi0933 family
GPY46_RS09450	ENOG4108JUA	Transcriptional regulator
GPY46_RS09455	ENOG4105K3G	Periplasmic Protein
GPY46_RS09505	ENOG4105DSF	transport protein
GPY46_RS09510	ENOG4105BZU	Histidine kinase
GPY46_RS09520	ENOG4105CGY	Dna recombination protein
GPY46_RS09525	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GPY46_RS09530	ENOG4105JC1	sterol-binding domain protein
GPY46_RS09535	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GPY46_RS09540	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GPY46_RS09545	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
GPY46_RS09550	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GPY46_RS09560	ENOG4105F8V	Hydrolase, tatD family
GPY46_RS09570	ENOG4105D52	delta-aminolevulinic acid dehydratase
GPY46_RS09585	ENOG4105C2M	dna polymerase I
GPY46_RS09595	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GPY46_RS09600	ENOG4106RE7	Cytochrome
GPY46_RS09620	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
GPY46_RS09625	ENOG4105XCT	Protein of unknown function (DUF2489)
GPY46_RS09630	ENOG4105D4P	Coproporphyrinogen iii oxidase
GPY46_RS09635	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
GPY46_RS09640	ENOG4105BZU	Histidine kinase
GPY46_RS09645	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY46_RS09650	ENOG4105CUX	Signal transduction histidine kinase
GPY46_RS09660	ENOG4105C5F	glutamine synthetase
GPY46_RS09680	ENOG4107S2Z	UPF0761 membrane protein
GPY46_RS09685	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GPY46_RS09690	ENOG4105SUU	thioesterase domain
GPY46_RS09700	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GPY46_RS09705	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GPY46_RS09710	ENOG4105VEJ	Heat shock protein
GPY46_RS09715	ENOG4108XKW	General secretion pathway protein C
GPY46_RS09725	ENOG4107QHF	type ii secretion system protein e
GPY46_RS09730	ENOG4105D7Q	type ii secretion system
GPY46_RS09735	ENOG4108VAU	general secretion pathway protein G
GPY46_RS09740	ENOG4105VWV	general secretion pathway protein h
GPY46_RS09745	ENOG4105X5Z	General secretion pathway protein I
GPY46_RS09750	ENOG4108WWZ	General secretion pathway protein J
GPY46_RS09755	ENOG4108RTD	type II secretion system protein K
GPY46_RS09760	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
GPY46_RS09765	ENOG4105U1E	general secretion pathway protein M
GPY46_RS09770	ENOG4105PIC	general secretion pathway protein N
GPY46_RS09780	ENOG4107RK2	ADP-ribose diphosphatase NudE
GPY46_RS09785	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
GPY46_RS09790	ENOG4105MJ2	Competence protein
GPY46_RS09795	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GPY46_RS09805	ENOG4105BZM	domain protein
GPY46_RS09815	ENOG4108RRZ	Transcription elongation factor GreB
GPY46_RS09825	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GPY46_RS09830	ENOG4105E0F	Histidine kinase
GPY46_RS09835	ENOG4105C2W	permease
GPY46_RS09840	ENOG4105CB5	ATP-dependent DNA helicase recG
GPY46_RS09845	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
GPY46_RS09850	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GPY46_RS09855	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GPY46_RS09860	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GPY46_RS09875	ENOG4109015	Biopolymer transport protein exbD tolR
GPY46_RS09895	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GPY46_RS09905	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
GPY46_RS09910	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
GPY46_RS09915	ENOG4107QRA	Extracellular solute-binding protein, family 5
GPY46_RS09925	ENOG4108JQ7	(ABC) transporter
GPY46_RS09935	ENOG4105DSJ	YicC domain protein
GPY46_RS09940	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GPY46_RS09945	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GPY46_RS09950	ENOG4105D1S	lipid A biosynthesis
GPY46_RS09955	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
GPY46_RS09960	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GPY46_RS09970	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY46_RS09975	ENOG4105W5Q	DNA repair protein (RadC
GPY46_RS09980	ENOG4105KDC	50s ribosomal protein l28
GPY46_RS09995	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GPY46_RS10000	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GPY46_RS10005	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
GPY46_RS10015	ENOG4106WTF	Glycosyl transferase, family 2
GPY46_RS10020	ENOG4105DKP	glycosyl transferase, family 9
GPY46_RS10025	ENOG41080IJ	Diacylglycerol kinase
GPY46_RS10030	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
GPY46_RS10035	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GPY46_RS10040	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
GPY46_RS10080	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GPY46_RS10085	ENOG4105XA0	heptosyltransferase ii
GPY46_RS10095	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
GPY46_RS10100	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GPY46_RS10105	ENOG4105E3R	(LipO)protein
GPY46_RS10130	ENOG4105DAY	polysaccharide export protein
GPY46_RS10155	ENOG4105CG5	Glycosyl transferase (Group 1
GPY46_RS10165	ENOG4107RA4	Glycosyl transferase (Group 1
GPY46_RS10185	ENOG4105ESV	Glycosyl transferase, family 4
GPY46_RS10210	ENOG4105K64	Glycosyl transferase, family 2
GPY46_RS10215	ENOG4107XU6	Glycosyl transferase (Group 1
GPY46_RS10265	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GPY46_RS10270	ENOG4105CP7	Triose-phosphate isomerase
GPY46_RS10295	ENOG4105CBT	Fructose-1,6-bisphosphatase
GPY46_RS10305	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
GPY46_RS10310	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GPY46_RS10315	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GPY46_RS10320	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GPY46_RS10325	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GPY46_RS10335	ENOG4105ETE	Transcriptional regulator (LacI family
GPY46_RS10340	ENOG4105C25	Primosomal protein n'
GPY46_RS10350	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GPY46_RS10355	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GPY46_RS10360	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GPY46_RS10365	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GPY46_RS10370	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GPY46_RS10375	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPY46_RS10380	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GPY46_RS10385	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GPY46_RS10390	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GPY46_RS10395	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GPY46_RS10400	ENOG41083MP	50s ribosomal protein l29
GPY46_RS10405	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GPY46_RS10410	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GPY46_RS10415	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GPY46_RS10420	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPY46_RS10425	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GPY46_RS10430	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GPY46_RS10435	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GPY46_RS10445	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GPY46_RS10450	ENOG4105VPB	50S ribosomal protein L30
GPY46_RS10455	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GPY46_RS10460	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GPY46_RS10470	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPY46_RS10475	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GPY46_RS10480	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GPY46_RS10485	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GPY46_RS10490	ENOG4108ZT0	50S ribosomal protein l17
GPY46_RS10500	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GPY46_RS10510	ENOG4107YB6	acetyltransferase, (GNAT) family
GPY46_RS10515	ENOG4105C1J	atp-dependent rna helicase
GPY46_RS10525	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
GPY46_RS10530	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GPY46_RS10535	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GPY46_RS10540	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
GPY46_RS10555	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
GPY46_RS10575	ENOG4108I0Y	(ABC) transporter
GPY46_RS10590	ENOG4108UUE	Transcriptional regulator
GPY46_RS10595	ENOG41061GZ	Protein of unknown function (DUF1107)
GPY46_RS10600	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GPY46_RS10605	ENOG4105CFU	surface antigen
GPY46_RS10615	ENOG41066HZ	AIG2-like family
GPY46_RS10625	ENOG4105F0N	pyrophosphate phospho-hydrolase
GPY46_RS10630	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GPY46_RS10640	ENOG4105DFU	Cell wall formation (By similarity)
GPY46_RS10645	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GPY46_RS10650	ENOG4105DP9	ABC transporter
GPY46_RS10655	ENOG4106SMU	thiamine transporter membrane protein
GPY46_RS10660	ENOG4107T0D	ABC, transporter
GPY46_RS10690	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
GPY46_RS10695	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GPY46_RS10705	ENOG4105EAH	synthase
GPY46_RS10710	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GPY46_RS10715	ENOG4105K46	50S ribosomal protein l27
GPY46_RS10720	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPY46_RS10725	ENOG4105DWK	Membrane
GPY46_RS10735	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
GPY46_RS10740	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GPY46_RS10745	ENOG4105NWN	ApaG protein
GPY46_RS10750	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GPY46_RS10755	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GPY46_RS10760	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GPY46_RS10765	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GPY46_RS10770	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GPY46_RS10780	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GPY46_RS10785	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GPY46_RS10790	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GPY46_RS10795	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GPY46_RS10820	ENOG41064T2	transcriptional regulator, lysR family
GPY46_RS10825	ENOG4108IQE	Amp-dependent synthetase and ligase
GPY46_RS10830	ENOG4105C7K	acetolactate synthase
GPY46_RS10835	ENOG4108ZP8	Acetolactate synthase small subunit
GPY46_RS10840	ENOG4105BZU	Histidine kinase
GPY46_RS10850	ENOG4105CA9	Pyruvate kinase
GPY46_RS10860	ENOG410804X	Transcriptional regulator
GPY46_RS10865	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GPY46_RS10880	ENOG4105GR3	Histidine kinase
GPY46_RS10885	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
GPY46_RS10890	ENOG4105E61	Mannitol repressor protein
GPY46_RS10895	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
GPY46_RS10900	ENOG4105CTS	PTS system mannitol-specific
GPY46_RS10945	ENOG4105D01	(LipO)protein
GPY46_RS10995	ENOG4108YGG	dna repair protein
GPY46_RS11050	ENOG4105DFP	Integrase
GPY46_RS11060	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPY46_RS11065	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GPY46_RS11070	ENOG4105KTH	gatB Yqey
GPY46_RS11075	ENOG4105VCC	30S ribosomal protein S21
GPY46_RS11080	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GPY46_RS11085	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
GPY46_RS11090	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GPY46_RS11095	ENOG4107ZVW	dihydroneopterin aldolase
GPY46_RS11100	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY46_RS11105	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GPY46_RS11110	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GPY46_RS11125	ENOG4106MWK	domain protein
GPY46_RS11130	ENOG4105CJ3	phosphate transporter
GPY46_RS11135	ENOG4107IX6	phosphate transport regulator
GPY46_RS11140	ENOG4105I7R	Adenylate cyclase
GPY46_RS11150	ENOG4108NVR	Methyl-accepting chemotaxis
GPY46_RS11155	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
GPY46_RS11160	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GPY46_RS11165	ENOG4105DFG	type I secretion outer membrane protein
GPY46_RS11170	ENOG41087AY	ADP-Ribose pyrophosphatase
GPY46_RS11175	ENOG4108SX3	cytoplasmic protein
GPY46_RS11180	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
GPY46_RS11185	ENOG4105IPS	esterase
GPY46_RS11190	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPY46_RS11195	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPY46_RS11200	ENOG4105C0H	protease
GPY46_RS11205	ENOG4105C0H	protease
GPY46_RS11210	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
GPY46_RS11220	ENOG4105D6Z	AFG1 family ATPase
GPY46_RS11230	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GPY46_RS11235	ENOG4108UJD	30S ribosomal protein S9
GPY46_RS11240	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GPY46_RS11245	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GPY46_RS11250	ENOG4105EIX	cytochrome c1
GPY46_RS11255	ENOG4107MKT	Stringent starvation protein a
GPY46_RS11260	ENOG4105KB2	stringent starvation protein b
GPY46_RS11265	ENOG4105W4M	Transport-associated protein
GPY46_RS11270	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GPY46_RS11275	ENOG41082RQ	UPF0102 protein
GPY46_RS11285	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GPY46_RS11300	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GPY46_RS11305	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GPY46_RS11310	ENOG4105CJN	penicillin-binding protein
GPY46_RS11315	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GPY46_RS11320	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GPY46_RS11325	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GPY46_RS11330	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GPY46_RS11340	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GPY46_RS11345	ENOG4105DFU	Cell wall formation (By similarity)
GPY46_RS11350	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GPY46_RS11355	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GPY46_RS11360	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GPY46_RS11365	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPY46_RS11375	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GPY46_RS11380	ENOG4105M6F	mutator MutT protein
GPY46_RS11385	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GPY46_RS11390	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GPY46_RS11395	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GPY46_RS11410	ENOG4105EJ9	Membrane
GPY46_RS11415	ENOG4105VP0	transcriptional regulator, lysR family
GPY46_RS11420	ENOG4105EN6	Membrane
GPY46_RS11425	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
GPY46_RS11430	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
GPY46_RS11435	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GPY46_RS11445	ENOG4105BZ8	glutamate synthase
GPY46_RS11450	ENOG4105CBC	glutamate synthase
GPY46_RS11465	ENOG4105N5T	Radical SAM Protein
GPY46_RS11475	ENOG4105BZU	Histidine kinase
GPY46_RS11485	ENOG41065U4	response regulator
GPY46_RS11500	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
GPY46_RS11515	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GPY46_RS11520	ENOG4105D98	threonine synthase
GPY46_RS11525	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
GPY46_RS11530	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GPY46_RS11540	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GPY46_RS11555	ENOG4105BZG	amino acid carrier protein
GPY46_RS11560	ENOG4105D1Q	UPF0246 protein
GPY46_RS11565	ENOG4105C1J	atp-dependent rna helicase
GPY46_RS11570	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GPY46_RS11575	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
GPY46_RS11580	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
GPY46_RS11585	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GPY46_RS11590	ENOG4105T95	Thiol disulfide interChange protein
GPY46_RS11595	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GPY46_RS11610	ENOG4105CRK	lysyL-tRNA synthetase
GPY46_RS11615	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY46_RS11625	ENOG4105CPC	Aldo Keto reductase
GPY46_RS11635	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
GPY46_RS11645	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GPY46_RS11650	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
GPY46_RS11655	ENOG4105HF0	Membrane
GPY46_RS11660	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GPY46_RS11665	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GPY46_RS11680	ENOG41063Z6	transcriptional regulator, lysR family
GPY46_RS11690	ENOG41080HT	Transcriptional regulator, arsr family
GPY46_RS11700	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GPY46_RS11705	ENOG4105CJR	Integral membrane protein (MviN
GPY46_RS11710	ENOG4105DTN	riboflavin biosynthesis protein ribF
GPY46_RS11715	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GPY46_RS11720	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GPY46_RS11725	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GPY46_RS11730	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GPY46_RS11735	ENOG4108NEV	two component transcriptional regulator, LytTR family
GPY46_RS11740	ENOG4108HRK	Histidine kinase
GPY46_RS11760	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPY46_RS11765	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
GPY46_RS11770	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
GPY46_RS11775	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GPY46_RS11780	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
GPY46_RS11785	ENOG4105DR5	peptidase
GPY46_RS11800	ENOG4105C5H	ABC transporter
GPY46_RS11805	ENOG4107SC1	transglycosylase
GPY46_RS11810	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
GPY46_RS11815	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GPY46_RS11825	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
GPY46_RS11830	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GPY46_RS11835	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GPY46_RS11840	ENOG4105C34	Pseudouridine synthase
GPY46_RS11845	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GPY46_RS11850	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GPY46_RS11915	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
GPY46_RS11920	ENOG4105CFP	Peptidase U32
GPY46_RS11925	ENOG4105DH7	May be involved in recombination (By similarity)
GPY46_RS11930	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GPY46_RS11935	ENOG4105BZU	Histidine kinase
GPY46_RS11945	ENOG4105C9X	ppx gppa phosphatase
GPY46_RS11950	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GPY46_RS11955	ENOG4105C8U	phosphate abc transporter
GPY46_RS11960	ENOG4105E2Z	phosphate ABC transporter (Permease
GPY46_RS11965	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GPY46_RS11975	ENOG4105CSR	polyphosphate kinase 2
GPY46_RS11980	ENOG4106N3A	copper homeostasis protein cutc
GPY46_RS11985	ENOG4105D3R	alkyl hydroperoxide reductase
GPY46_RS11990	ENOG4105C5Q	Transcriptional regulator
GPY46_RS12000	ENOG4107QP3	malate synthase g
GPY46_RS12005	ENOG4108I9X	Isocitrate lyase
GPY46_RS12010	ENOG4105W87	Cbs domain
GPY46_RS12020	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GPY46_RS12025	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GPY46_RS12030	ENOG4105VIE	preprotein translocase, subunit YajC
GPY46_RS12035	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPY46_RS12040	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GPY46_RS12050	ENOG4105ECY	inositol monophosphatase
GPY46_RS12055	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
GPY46_RS12060	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
GPY46_RS12065	ENOG4105C3J	Cysteine desulfurase
GPY46_RS12070	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
GPY46_RS12075	ENOG4108Z4V	iron-sulfur cluster assembly
GPY46_RS12080	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
GPY46_RS12085	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
GPY46_RS12090	ENOG4108ZIT	Ferredoxin, 2FE-2S
GPY46_RS12095	ENOG4105WVQ	Fe-S assembly protein IscX
GPY46_RS12100	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GPY46_RS12105	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GPY46_RS12110	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GPY46_RS12125	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GPY46_RS12130	ENOG4105CUT	histidyl-tRNA synthetase
GPY46_RS12135	ENOG4105N21	Membrane
GPY46_RS12140	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GPY46_RS12145	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GPY46_RS12160	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GPY46_RS12165	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GPY46_RS12170	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GPY46_RS12175	ENOG4107S6Z	Na H antiporter
GPY46_RS12185	ENOG4106HK8	GPR1 FUN34 yaaH family protein
GPY46_RS12195	ENOG4105BZG	amino acid carrier protein
GPY46_RS12200	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GPY46_RS12230	ENOG4108IQK	o-acetylhomoserine
GPY46_RS12235	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GPY46_RS12255	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
GPY46_RS12260	ENOG4105ETT	transcriptional Regulator, LysR family
GPY46_RS12280	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GPY46_RS12285	ENOG4108Z1B	Cyclase dehydrase
GPY46_RS12290	ENOG4105VDB	UPF0125 protein
GPY46_RS12295	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GPY46_RS12300	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GPY46_RS12310	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GPY46_RS12315	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPY46_RS12325	ENOG4105CFG	Acts as a chaperone (By similarity)
GPY46_RS12330	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GPY46_RS12365	ENOG4105CFC	Transporter
GPY46_RS12370	ENOG4108Z6B	deaminase
GPY46_RS12380	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GPY46_RS12385	ENOG4108ETH	Formylglycinamide ribotide synthetase
GPY46_RS12410	ENOG4105CIN	aminoacyl-histidine dipeptidase
GPY46_RS12415	ENOG4105C7N	Xanthine uracil vitamin C permease
GPY46_RS12420	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
GPY46_RS12425	ENOG4108DJV	Fermentation respiration switch protein
GPY46_RS12430	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
GPY46_RS12435	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GPY46_RS12440	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GPY46_RS12445	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GPY46_RS12450	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GPY46_RS12465	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GPY46_RS12470	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GPY46_RS12475	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GPY46_RS12480	ENOG4108ZAI	phosphatidylglycerophosphatase a
GPY46_RS12485	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GPY46_RS12490	ENOG4105CTB	Polyprenyl synthetase
GPY46_RS12495	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GPY46_RS12500	ENOG4105E14	MotA TolQ exbB proton channel
GPY46_RS12505	ENOG4107QKZ	Ompa motb domain protein
GPY46_RS12510	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GPY46_RS12515	ENOG4105ETT	transcriptional Regulator, LysR family
GPY46_RS12525	ENOG4105M08	Membrane
GPY46_RS12530	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
GPY46_RS12540	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
GPY46_RS12545	ENOG4105EWT	decarboxylase family
GPY46_RS12550	ENOG4105BZU	Histidine kinase
GPY46_RS12560	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GPY46_RS12565	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
GPY46_RS12570	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
GPY46_RS12575	ENOG4105D01	(LipO)protein
GPY46_RS12580	ENOG4108UMI	ABC transporter, permease
GPY46_RS12585	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GPY46_RS12595	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
GPY46_RS12600	ENOG4105D4X	repressor
GPY46_RS12605	ENOG4105C5Y	PTS System
GPY46_RS12610	ENOG4105CG3	alpha amylase, catalytic region
GPY46_RS12625	ENOG4108JYZ	YitT family
GPY46_RS12630	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GPY46_RS12635	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GPY46_RS12640	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GPY46_RS12645	ENOG4108Z43	UPF0250 protein
GPY46_RS12650	ENOG4105DZ1	carboxypeptidase
GPY46_RS12655	ENOG4105K6T	rare lipoprotein A
GPY46_RS12660	ENOG4105CNI	cell division protein FtsW
GPY46_RS12665	ENOG4105CJN	penicillin-binding protein
GPY46_RS12670	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GPY46_RS12675	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GPY46_RS12680	ENOG4105DJF	DNA polymerase III, delta' subunit
GPY46_RS12685	ENOG4108U2H	Rare lipoprotein B
GPY46_RS12690	ENOG4105C8T	Leucyl-tRNA synthetase
GPY46_RS12695	ENOG4107PAI	alpha helical protein
GPY46_RS12700	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GPY46_RS12705	ENOG4108JU5	Magnesium and cobalt efflux protein
GPY46_RS12710	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GPY46_RS12715	ENOG4105C9A	Phoh family
GPY46_RS12720	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GPY46_RS12730	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GPY46_RS12845	ENOG4105C3G	gtp-binding protein
GPY46_RS12850	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GPY46_RS12855	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GPY46_RS12860	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GPY46_RS12865	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
GPY46_RS12870	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
GPY46_RS12875	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GPY46_RS12880	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GPY46_RS12885	ENOG4108YY7	Invasion gene expression up-regulator SirB
GPY46_RS12890	ENOG41063JG	Transcriptional regulator
GPY46_RS12895	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GPY46_RS12900	ENOG4105CGH	5'-nucleotidase
GPY46_RS12905	ENOG4108Z66	YbaK ebsC protein
GPY46_RS12910	ENOG4105FE9	pseudouridine synthase
GPY46_RS12915	ENOG4108DG9	Smr protein MutS2
GPY46_RS12940	ENOG4105E2D	ec 3.2.1.52
GPY46_RS12955	ENOG4105C59	p-type ATPase
GPY46_RS12965	ENOG41081QG	Porin Gram-negative type
GPY46_RS12975	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GPY46_RS12985	ENOG4105UYK	outer membrane protein a
GPY46_RS13035	ENOG4107R88	Chemotaxis protein (CheV)
GPY46_RS13040	ENOG4105BZU	Histidine kinase
GPY46_RS13045	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GPY46_RS13050	ENOG4108ZC9	flagellar basal-body rod protein flgc
GPY46_RS13055	ENOG4105W00	Flagellar hook capping protein
GPY46_RS13060	ENOG4105BZE	flagellar hook protein, FlgE
GPY46_RS13070	ENOG4108KPB	Flagellar basal-body rod protein FlgF
GPY46_RS13075	ENOG4105CGA	flagellar basal-body rod protein FlgG
GPY46_RS13080	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GPY46_RS13085	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GPY46_RS13090	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
GPY46_RS13100	ENOG4105DTJ	flagellar hook-associated protein
GPY46_RS13110	ENOG4105I03	Flagellin
GPY46_RS13120	ENOG4105I03	Flagellin
GPY46_RS13135	ENOG4105C5Y	PTS System
GPY46_RS13140	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
GPY46_RS13145	ENOG4105KZ7	phosphocarrier protein hpr
GPY46_RS13155	ENOG4105C6T	cysteine synthase
GPY46_RS13160	ENOG4105EXN	Sulfate transport protein CysZ
GPY46_RS13165	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
GPY46_RS13170	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GPY46_RS13195	ENOG4107QX8	SPFH domain, Band 7 family protein
GPY46_RS13200	ENOG4107QR8	Thioredoxin
GPY46_RS13210	ENOG4105E1F	short-chain dehydrogenase reductase
GPY46_RS13215	ENOG4105ECP	epimerase
GPY46_RS13245	ENOG4108RE9	Phosphodiesterase
GPY46_RS13265	ENOG4108DQ1	activator toxR
GPY46_RS13270	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GPY46_RS13275	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GPY46_RS13280	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GPY46_RS13285	ENOG4105DUX	Transporter
GPY46_RS13290	ENOG4105MDZ	Transcriptional activator rfaH
GPY46_RS13295	ENOG4105CAQ	asparagine synthetase
GPY46_RS13300	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GPY46_RS13305	ENOG4105E2R	ROK family
GPY46_RS13310	ENOG4105CE4	GlcNAc 6-P deacetylase
GPY46_RS13320	ENOG4105CI1	PTS System
GPY46_RS13325	ENOG4105CX6	glutaminyL-tRNA synthetase
GPY46_RS13330	ENOG41090R7	Ferric uptake
GPY46_RS13340	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GPY46_RS13350	ENOG4105EV9	Alpha Beta Hydrolase
GPY46_RS13355	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
GPY46_RS13360	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
GPY46_RS13370	ENOG4107QNR	UPF0135 protein
GPY46_RS13375	ENOG4105BZN	citrate synthase
GPY46_RS13380	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GPY46_RS13385	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GPY46_RS13390	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GPY46_RS13395	ENOG4105E33	succinate dehydrogenase
GPY46_RS13400	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GPY46_RS13405	ENOG4105C7S	Dehydrogenase
GPY46_RS13410	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GPY46_RS13415	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GPY46_RS13420	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GPY46_RS13425	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GPY46_RS13430	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GPY46_RS13435	ENOG4105C2W	permease
GPY46_RS13455	ENOG4105ERG	peptidase m48, ste24p
GPY46_RS13470	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPY46_RS13475	ENOG4105RH4	Glycine cleavage system transcriptional repressor
GPY46_RS13485	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GPY46_RS13500	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GPY46_RS13505	ENOG4105KUZ	arsenate reductase
GPY46_RS13530	ENOG4105QZU	Inner membrane protein YfeZ
GPY46_RS13535	ENOG4105EZR	dyp-type peroxidase family protein
GPY46_RS13540	ENOG4105I03	Flagellin
GPY46_RS13550	ENOG4105I03	Flagellin
GPY46_RS13555	ENOG4105I03	Flagellin
GPY46_RS13560	ENOG41063QE	flagellar protein FlaG
GPY46_RS13565	ENOG4107BRV	flagellar capping protein
GPY46_RS13575	ENOG4105MQ3	flagellar protein FliS
GPY46_RS13580	ENOG4108JUA	Transcriptional regulator
GPY46_RS13585	ENOG4105BZU	Histidine kinase
GPY46_RS13590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY46_RS13595	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
GPY46_RS13600	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GPY46_RS13605	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GPY46_RS13615	ENOG4108JIR	Flagellum-specific ATP synthase
GPY46_RS13635	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GPY46_RS13640	ENOG4105DD5	Flagellar motor switch protein
GPY46_RS13645	ENOG4105VTB	flagellar biosynthesis protein fliO
GPY46_RS13650	ENOG4105CN7	Flagellar biosynthetic protein FliP
GPY46_RS13655	ENOG4105VS8	Flagellar biosynthetic protein fliq
GPY46_RS13660	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
GPY46_RS13665	ENOG4105D00	flagellar biosynthetic protein flhB
GPY46_RS13670	ENOG4105D7B	Flagellar biosynthesis protein flha
GPY46_RS13675	ENOG4105FZW	flagellar biosynthesis regulator FlhF
GPY46_RS13680	ENOG4107R21	site-determining protein
GPY46_RS13685	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPY46_RS13690	ENOG4108VYJ	response regulator receiver protein
GPY46_RS13695	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
GPY46_RS13700	ENOG4105CBS	Chea signal transduction histidine kinase
GPY46_RS13705	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GPY46_RS13710	ENOG4107QJE	Chromosome Partitioning Protein
GPY46_RS13720	ENOG4108V3W	Chemotaxis protein, CheW
GPY46_RS13730	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
GPY46_RS13735	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
GPY46_RS13740	ENOG41060IM	Heme exporter protein
GPY46_RS13745	ENOG4105X3C	heme exporter protein
GPY46_RS13750	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
GPY46_RS13755	ENOG4105DA4	cytochrome c-type biogenesis protein
GPY46_RS13760	ENOG4107QX9	Thiol disulfide interChange protein
GPY46_RS13765	ENOG4108M1T	Cytochrome c-type biogenesis protein
GPY46_RS13775	ENOG410903C	(LipO)protein
GPY46_RS13780	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GPY46_RS13785	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
GPY46_RS13800	ENOG4105CHU	acetyl-coa acetyltransferase
GPY46_RS13805	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
GPY46_RS13815	ENOG4107QXK	peptidase
GPY46_RS13820	ENOG4108BY2	phosphohistidine phosphatase
GPY46_RS13825	ENOG4108DG9	Smr protein MutS2
GPY46_RS13830	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GPY46_RS13835	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GPY46_RS13840	ENOG4105EN6	Membrane
GPY46_RS13850	ENOG4108BPE	-transporting atpase
GPY46_RS13855	ENOG4105MH2	YfcL protein
GPY46_RS13865	ENOG4105Q8W	reductase
GPY46_RS13870	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
GPY46_RS13875	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GPY46_RS13880	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GPY46_RS13885	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GPY46_RS13895	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GPY46_RS13900	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GPY46_RS13905	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GPY46_RS13910	ENOG4108S3P	Sporulation domain protein
GPY46_RS13915	ENOG4105E96	Colicin v production protein
GPY46_RS13920	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GPY46_RS13925	ENOG4105EJC	lysr family transcriptional regulator
GPY46_RS13930	ENOG4105I93	response regulator
GPY46_RS13940	ENOG4105WD1	Membrane
GPY46_RS13945	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GPY46_RS13950	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GPY46_RS13955	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GPY46_RS13960	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GPY46_RS13965	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GPY46_RS13970	ENOG4105C44	Serine transporter
GPY46_RS13980	ENOG4105CEM	UPF0597 protein
GPY46_RS13990	ENOG4105KRS	Proteinase inhibitor
GPY46_RS13995	ENOG4105Y3U	Transglycosylase-associated protein
GPY46_RS14000	ENOG4108ZZ3	UPF0260 protein
GPY46_RS14010	ENOG41067V3	Antibiotic biosynthesis monooxygenase
GPY46_RS14015	ENOG4108UYE	Lactoylglutathione lyase
GPY46_RS14025	ENOG4105G6Z	alkaline phosphatase
GPY46_RS14045	ENOG4105DHI	Methyltransferase
GPY46_RS14050	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY46_RS14055	ENOG4105DSB	aldose 1-epimerase
GPY46_RS14060	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GPY46_RS14065	ENOG4105E0X	reductase
GPY46_RS14075	ENOG4105VUT	cytoplasmic protein
GPY46_RS14080	ENOG4105HDK	L-asparaginase
GPY46_RS14085	ENOG4105D07	Signal peptide peptidase, SppA
GPY46_RS14090	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GPY46_RS14095	ENOG41069NU	Nitroreductase
GPY46_RS14100	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GPY46_RS14115	ENOG4108RU0	short-chain dehydrogenase reductase
GPY46_RS14120	ENOG4105DGU	Histone deacetylase
GPY46_RS14130	ENOG4105E68	Sulfatase
GPY46_RS14135	ENOG4105YDX	UPF0352 protein
GPY46_RS14140	ENOG4106V8H	Nucleoid-associated protein
GPY46_RS14155	ENOG4105DFD	Na H antiporter
GPY46_RS14160	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GPY46_RS14165	ENOG4105EYW	Ion transport protein
GPY46_RS14170	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GPY46_RS14175	ENOG4108EKI	Dehydrogenase
GPY46_RS14190	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GPY46_RS14195	ENOG4105M2J	Glutaredoxin
GPY46_RS14205	ENOG4105D3Y	Na H antiporter
GPY46_RS14210	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GPY46_RS14225	ENOG4105EIY	sodium-type flagellar protein motY
GPY46_RS14230	ENOG4106WH9	Protein of unknown function (DUF2753)
GPY46_RS14235	ENOG4108UYE	Lactoylglutathione lyase
GPY46_RS14240	ENOG4105CSM	endonuclease III
GPY46_RS14245	ENOG4105DZB	Electron transport complex
GPY46_RS14250	ENOG4108UQQ	Electron transport complex
GPY46_RS14255	ENOG4105D6A	Electron transport complex
GPY46_RS14265	ENOG4108R3D	Electron transport complex
GPY46_RS14270	ENOG4105DGN	Electron transport complex
GPY46_RS14285	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GPY46_RS14290	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY46_RS14300	ENOG4105CHW	UPF0052 protein
GPY46_RS14305	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GPY46_RS14310	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
GPY46_RS14315	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GPY46_RS14320	ENOG4105M00	molybdopterin converting factor, subunit 1
GPY46_RS14325	ENOG4108ZAF	Molybdopterin
GPY46_RS14330	ENOG4107QSI	ABC, transporter
GPY46_RS14335	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GPY46_RS14340	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPY46_RS14345	ENOG4105C3U	ABC transporter
GPY46_RS14350	ENOG4108JQ7	(ABC) transporter
GPY46_RS14355	ENOG4105CHF	Glutathione S-transferase
GPY46_RS14365	ENOG4107PU6	Membrane
GPY46_RS14370	ENOG4108DNC	Involved in acetate metabolism (By similarity)
GPY46_RS14375	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GPY46_RS14380	ENOG4105PQ6	UPF0208 membrane protein
GPY46_RS14390	ENOG4105C7J	ABC transporter, permease
GPY46_RS14395	ENOG4108JJB	ABC transporter
GPY46_RS14400	ENOG4107R28	alpha amylase, catalytic region
GPY46_RS14405	ENOG4105BZU	Histidine kinase
GPY46_RS14410	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
GPY46_RS14415	ENOG4106RHG	Yeca family
GPY46_RS14420	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GPY46_RS14425	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GPY46_RS14430	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
GPY46_RS14440	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GPY46_RS14445	ENOG4105D1F	ATP-binding protein
GPY46_RS14450	ENOG4105DBI	uridine monophosphokinase
GPY46_RS14460	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
GPY46_RS14470	ENOG4105CHH	sulfate transporter
GPY46_RS14475	ENOG4105C03	ribonuclease
GPY46_RS14480	ENOG4105EI2	Pseudouridine synthase
GPY46_RS14485	ENOG4108UHJ	MAF-like protein
GPY46_RS14490	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
GPY46_RS14495	ENOG4105VGS	50s ribosomal protein l32
GPY46_RS14500	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GPY46_RS14505	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GPY46_RS14510	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GPY46_RS14515	ENOG4105CHR	reductase
GPY46_RS14520	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GPY46_RS14525	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GPY46_RS14535	ENOG4105HHA	aminodeoxychorismate lyase
GPY46_RS14540	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GPY46_RS14545	ENOG4107QRG	dna polymerase iii
GPY46_RS14550	ENOG4105F8V	Hydrolase, tatD family
GPY46_RS14555	ENOG4105CI1	PTS System
GPY46_RS14575	ENOG4105C8J	)-transporter
GPY46_RS14590	ENOG4108NRW	Phospholipase, patatin family
GPY46_RS14595	ENOG4105CA9	Pyruvate kinase
GPY46_RS14600	ENOG4105DAG	ROK family
GPY46_RS14605	ENOG4107R88	Chemotaxis protein (CheV)
GPY46_RS14610	ENOG4105C0B	DNA polymerase III (alpha subunit)
GPY46_RS14625	ENOG4105UBK	short-chain dehydrogenase reductase
GPY46_RS14630	ENOG4105ERU	peptidase
GPY46_RS14635	ENOG4105CAT	Cytidine monophosphate kinase
GPY46_RS14640	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GPY46_RS14645	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GPY46_RS14650	ENOG4105Q4A	inner membrane protein yciS
GPY46_RS14655	ENOG4105CFV	Tetratricopeptide repeat protein
GPY46_RS14660	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GPY46_RS14665	ENOG4108J59	Extracellular solute-binding protein, family 5
GPY46_RS14680	ENOG4105CKK	Glycosyl transferase, family 2
GPY46_RS14690	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GPY46_RS14700	ENOG4105DY2	Paraquat-inducible protein b
GPY46_RS14705	ENOG4105F1S	paraquat-inducible protein a
GPY46_RS14710	ENOG4105NQN	cytochrome C
GPY46_RS14720	ENOG4105DB1	molybdopterin oxidoreductase
GPY46_RS14725	ENOG4106WHD	Tetrathionate reductase
GPY46_RS14730	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GPY46_RS14735	ENOG4106AFQ	Histidine kinase
GPY46_RS14740	ENOG4108ZXC	Two component transcriptional regulator, luxr family
GPY46_RS14745	ENOG4105EXG	Transcriptional regulator
GPY46_RS14755	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GPY46_RS14760	ENOG4105N6Y	Thioredoxin
GPY46_RS14775	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GPY46_RS14790	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GPY46_RS14800	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GPY46_RS14805	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GPY46_RS14810	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GPY46_RS14815	ENOG4108W2Y	isochorismatase
GPY46_RS14820	ENOG41063TF	transcriptional regulator (AraC
GPY46_RS14830	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GPY46_RS14840	ENOG4105J12	Multidrug resistance protein mdtN
GPY46_RS14845	ENOG4105JQN	Transcriptional regulator
GPY46_RS14865	ENOG41062D9	Histidine kinase
GPY46_RS14870	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GPY46_RS14880	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY46_RS14885	ENOG4105CCT	upf0313 protein
GPY46_RS14905	ENOG4105DZ2	Transcriptional regulator
GPY46_RS14915	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GPY46_RS14925	ENOG4105K9H	YciI-like protein
GPY46_RS14930	ENOG4105NAU	thioesterase Superfamily protein
GPY46_RS14935	ENOG4107835	probably involved in intracellular septation (By similarity)
GPY46_RS14945	ENOG4105BZU	Histidine kinase
GPY46_RS14955	ENOG4105CK2	sodium dicarboxylate symporter
GPY46_RS14965	ENOG4105CEY	Amp-dependent synthetase and ligase
GPY46_RS14970	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GPY46_RS14975	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GPY46_RS14980	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GPY46_RS14985	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GPY46_RS14990	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GPY46_RS14995	ENOG4105DDQ	anthranilate synthase
GPY46_RS15000	ENOG4105CRQ	synthase (Component I)
GPY46_RS15010	ENOG4105DB7	PHP domain protein
GPY46_RS15015	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GPY46_RS15025	ENOG4105FE9	pseudouridine synthase
GPY46_RS15035	ENOG4108W5H	UPF0263 protein
GPY46_RS15040	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GPY46_RS15050	ENOG4105CQ2	DNA polymerase
GPY46_RS15055	ENOG4105WH1	Two component transcriptional regulator luxr family
GPY46_RS15060	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GPY46_RS15100	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
GPY46_RS15125	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GPY46_RS15130	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GPY46_RS15135	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GPY46_RS15140	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GPY46_RS15155	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
GPY46_RS15165	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
GPY46_RS15170	ENOG4105DVI	reductase, NrfD
GPY46_RS15175	ENOG4105DA4	cytochrome c-type biogenesis protein
GPY46_RS15180	ENOG4107QX9	Thiol disulfide interChange protein
GPY46_RS15185	ENOG4108DMF	Cytochrome C biogenesis protein
GPY46_RS15195	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GPY46_RS15220	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
GPY46_RS15225	ENOG4105EAQ	(twin-arginine translocation) pathway signal
GPY46_RS15230	ENOG4105C5X	domain protein
GPY46_RS15245	ENOG4105CH5	extracellular solute-binding protein, family 7
GPY46_RS15255	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPY46_RS15270	ENOG41067TZ	transcriptional regulator, MarR family
GPY46_RS15275	ENOG4105C94	Transporter
GPY46_RS15280	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY46_RS15300	ENOG4105CGF	Aromatic amino acid aminotransferase
GPY46_RS15325	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
GPY46_RS15335	ENOG4105C5S	asparaginyl-tRNA synthetase
GPY46_RS15340	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY46_RS15345	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
GPY46_RS15355	ENOG4105BZU	Histidine kinase
GPY46_RS15360	ENOG4105EJQ	L-serine dehydratase
GPY46_RS15365	ENOG4105C44	Serine transporter
GPY46_RS15370	ENOG4105P8F	nudix hydrolase
GPY46_RS15380	ENOG4105BZU	Histidine kinase
GPY46_RS15385	ENOG4105CRQ	synthase (Component I)
GPY46_RS15405	ENOG4105CM6	amino acid regulated cytosolic protein
GPY46_RS15410	ENOG4106K28	UPF0283 membrane protein
GPY46_RS15420	ENOG4105D9U	N-acetyltransferase
GPY46_RS15575	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
GPY46_RS15705	ENOG410829K	Lysine exporter protein (Lyse ygga)
GPY46_RS15955	ENOG4105D9P	serine threonine protein kinase
GPY46_RS16140	ENOG4105Y49	secretion protein, HlyD family
GPY46_RS16160	ENOG4105DUM	transcriptional regulator, lysR family
GPY46_RS16195	ENOG4105C8P	)-transporter
GPY46_RS16200	ENOG4105BZU	Histidine kinase
GPY46_RS16205	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY46_RS16210	ENOG4105BZU	Histidine kinase
GPY46_RS16215	ENOG4105CPI	Metal Dependent Phosphohydrolase
GPY46_RS16225	ENOG4105G0K	glycine radical enzyme YjjI family
GPY46_RS16230	ENOG41076CZ	activating enzyme
GPY46_RS16240	ENOG4105EE5	Membrane protein terC
GPY46_RS16250	ENOG4105DHT	Metal Dependent Phosphohydrolase
GPY46_RS16265	ENOG4105E0U	tyrosine-specific transport protein
GPY46_RS16290	ENOG4105BZ1	(ABC) transporter
GPY46_RS16295	ENOG4105BZ1	(ABC) transporter
GPY46_RS16325	ENOG4105CFG	Acts as a chaperone (By similarity)
GPY46_RS16330	ENOG4105CFG	Acts as a chaperone (By similarity)
GPY46_RS16340	ENOG4105BZU	Histidine kinase
GPY46_RS16370	ENOG4107QY8	reductase
GPY46_RS16375	ENOG4105QAX	Iron-sulfur
GPY46_RS16380	ENOG4107KGK	dmso reductase anchor subunit
GPY46_RS16385	ENOG4108NEM	leader-binding protein dmsD
GPY46_RS16395	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
GPY46_RS16400	ENOG4105CQ7	ATP-dependent helicase
GPY46_RS16415	ENOG4105C94	Transporter
GPY46_RS16430	ENOG4105CND	Glycosyl transferase, family 2
GPY46_RS16435	ENOG4105CPK	Glycosyl transferase (Group 1
GPY46_RS16480	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY46_RS16500	ENOG4107V1M	polysaccharide export protein
GPY46_RS16510	ENOG41082AN	stage II sporulation protein
GPY46_RS16525	ENOG4107QI1	Mate efflux family protein
GPY46_RS16530	ENOG4108R6K	riboflavin synthase, subunit alpha
GPY46_RS16540	ENOG4105FGM	Fructosamine kinase
GPY46_RS16545	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
GPY46_RS16550	ENOG4105BZU	Histidine kinase
GPY46_RS16560	ENOG4107TT5	NLP P60 protein
GPY46_RS16565	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY46_RS16600	ENOG4106IUH	DTW domain containing protein
GPY46_RS16605	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
GPY46_RS16615	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
GPY46_RS16620	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
GPY46_RS16625	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPY46_RS16645	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY46_RS16650	ENOG4105BZU	Histidine kinase
GPY46_RS16660	ENOG4105C5H	ABC transporter
GPY46_RS16665	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
GPY46_RS16690	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
GPY46_RS16700	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
GPY46_RS16705	ENOG4105QAX	Iron-sulfur
GPY46_RS16835	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GPY46_RS16840	ENOG4107RUE	extracellular solute-binding protein family 1
GPY46_RS16845	ENOG4107RUE	extracellular solute-binding protein family 1
GPY46_RS16850	ENOG4105D38	putrescine abc transporter
GPY46_RS16855	ENOG4105F38	ABC transporter, permease
GPY46_RS16860	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPY46_RS16880	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GPY46_RS16890	ENOG4105Q9Y	Universal stress protein
GPY46_RS16895	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GPY46_RS16910	ENOG4105C59	p-type ATPase
GPY46_RS16920	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
GPY46_RS16935	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
GPY46_RS16950	ENOG4105BZU	Histidine kinase
GPY46_RS16995	ENOG4105EQR	Transposase IS116 IS110 IS902
GPY46_RS17065	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
GPY46_RS17080	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
GPY46_RS17215	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
GPY46_RS17220	ENOG4105DAN	ATP-dependent protease
GPY46_RS17225	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
GPY46_RS17240	ENOG4105C5H	ABC transporter
GPY46_RS17250	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
GPY46_RS17260	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
GPY46_RS17265	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GPY46_RS17270	ENOG4105C7I	Dehydrogenase
GPY46_RS17280	ENOG4105CD8	aminopeptidase N
GPY46_RS17290	ENOG4105CN1	protease
GPY46_RS17295	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
GPY46_RS17300	ENOG4108ZGC	gaf domain protein
GPY46_RS17305	ENOG4105BZ1	(ABC) transporter
GPY46_RS17310	ENOG4105H2K	paraquat-inducible protein a
GPY46_RS17315	ENOG4105DY2	Paraquat-inducible protein b
GPY46_RS17320	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GPY46_RS17340	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GPY46_RS17345	ENOG4108VPT	UPF0234 protein
GPY46_RS17360	ENOG4107QXX	ABC transporter
GPY46_RS17365	ENOG4105EZ7	amino acid ABC transporter
GPY46_RS17370	ENOG4105DRP	amino acid AbC transporter
GPY46_RS17375	ENOG4105CDA	abc transporter atp-binding protein
GPY46_RS17380	ENOG4108MN8	Membrane
GPY46_RS17390	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GPY46_RS17395	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
GPY46_RS17400	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY46_RS17405	ENOG4105DR4	Methyltransferase
GPY46_RS17420	ENOG4105CDV	Ompa motb domain protein
GPY46_RS17435	ENOG4105CDV	Ompa motb domain protein
GPY46_RS17445	ENOG4105BZU	Histidine kinase
GPY46_RS17450	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GPY46_RS17455	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GPY46_RS17460	ENOG410667J	hydrolase
GPY46_RS17480	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GPY46_RS17485	ENOG4105C7F	AcnD-accessory protein PrpF
GPY46_RS17490	ENOG4108I0Z	Aconitate hydratase
GPY46_RS17495	ENOG4105BZN	citrate synthase
GPY46_RS17500	ENOG4105CR4	methylisocitrate lyase
GPY46_RS17530	ENOG4105EJ9	Membrane
GPY46_RS17640	ENOG4105EQ2	LysR family Transcriptional regulator
GPY46_RS17645	ENOG4105ENX	hydrolase
GPY46_RS17650	ENOG4105ENX	hydrolase
GPY46_RS17730	ENOG41066XE	Type III export protein
GPY46_RS17760	ENOG4108KB1	transcriptional regulator, arac family
GPY46_RS17780	ENOG4105C26	Dehydrogenase
GPY46_RS17785	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
GPY46_RS17805	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GPY46_RS17810	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
GPY46_RS17815	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GPY46_RS17820	ENOG4108V9W	transcriptional regulatory protein
GPY46_RS17825	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
GPY46_RS17840	ENOG4107V40	secretion protein, HlyD family
GPY46_RS17855	ENOG4105CA0	peroxidase
GPY46_RS17860	ENOG4105CZK	Aspartate kinase
GPY46_RS17865	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
GPY46_RS17870	ENOG4108JPW	Aminotransferase
GPY46_RS17875	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
GPY46_RS17880	ENOG4105C94	Transporter
GPY46_RS17895	ENOG4108IJ7	Glycine betaine
GPY46_RS17900	ENOG4108HQS	Glycine betaine
GPY46_RS17905	ENOG4105GIJ	Glycine betaine
GPY46_RS17940	ENOG4105DHQ	Histidine kinase
GPY46_RS17945	ENOG4105E0M	Sulfatase
GPY46_RS17970	ENOG4105BZG	amino acid carrier protein
GPY46_RS17980	ENOG410829K	Lysine exporter protein (Lyse ygga)
GPY46_RS17985	ENOG4105CTD	carboxy-peptidase
GPY46_RS17990	ENOG4105D1S	lipid A biosynthesis
GPY46_RS18000	ENOG4105E5D	amino acid
GPY46_RS18015	ENOG4105CVG	Homoserine O-transsuccinylase
GPY46_RS18020	ENOG41090FY	type IV pilus biogenesis stability protein PilW
GPY46_RS18030	ENOG4105BZU	Histidine kinase
GPY46_RS18035	ENOG4105BZU	Histidine kinase
GPY46_RS18050	ENOG4108UW5	maltose o-acetyltransferase
GPY46_RS18070	ENOG4105MSB	protein, conserved in bacteria
GPY46_RS18075	ENOG4108ZT1	Transcriptional regulator
GPY46_RS18090	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GPY46_RS18100	ENOG4105BZU	Histidine kinase
GPY46_RS18110	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
GPY46_RS18115	ENOG4108JPW	Aminotransferase
GPY46_RS18120	ENOG4105C26	Dehydrogenase
GPY46_RS18125	ENOG4105DWY	Agmatine deiminase
GPY46_RS18135	ENOG4105CJP	fad dependent oxidoreductase
GPY46_RS18140	ENOG4105C26	Dehydrogenase
GPY46_RS18145	ENOG4107VRI	Transcriptional regulator
GPY46_RS18150	ENOG4108Z86	Glutamine amidotransferase
GPY46_RS18160	ENOG4105CFQ	glutamine synthetase
GPY46_RS18165	ENOG4107S6Z	Na H antiporter
GPY46_RS18185	ENOG41068WN	
GPY46_RS18190	ENOG4105N14	lysine exporter protein LysE YggA
GPY46_RS18365	ENOG4108N0N	Phage Terminase Large Subunit
GPY46_RS18415	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GPY46_RS18420	ENOG4105VEQ	Cold shock protein
GPY46_RS18520	ENOG4108RXX	maleylacetoacetate isomerase
GPY46_RS18530	ENOG4105F1J	Homogentisate 1,2-dioxygenase
GPY46_RS18535	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
GPY46_RS18540	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GPY46_RS18545	ENOG4107QSI	ABC, transporter
GPY46_RS18550	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
GPY46_RS18555	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPY46_RS18560	ENOG4105C3U	ABC transporter
GPY46_RS18565	ENOG4108JQ7	(ABC) transporter
GPY46_RS18580	ENOG4107MM9	BNR Asp-box repeat-containing protein
GPY46_RS18590	ENOG4105D38	putrescine abc transporter
GPY46_RS18595	ENOG4105F38	ABC transporter, permease
GPY46_RS18600	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPY46_RS18605	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GPY46_RS18610	ENOG4105CIF	Ornithine Cyclodeaminase
GPY46_RS18630	ENOG4105CTU	Proline racemase
GPY46_RS18660	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
GPY46_RS18665	ENOG4108VKG	metal-dependent hydrolase
GPY46_RS18675	ENOG4107RSM	transcriptional regulator
GPY46_RS18695	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
GPY46_RS18700	ENOG4108IU2	vtamin B12-transporter permease
GPY46_RS18705	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
GPY46_RS18730	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
GPY46_RS18735	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
GPY46_RS18740	ENOG4105K4T	epimerase
GPY46_RS18745	ENOG4108ETY	sodium dicarboxylate symporter
GPY46_RS18750	ENOG4105CJB	Exodeoxyribonuclease I
GPY46_RS18755	ENOG4105VAW	lrga family
GPY46_RS18760	ENOG41067MG	lrgb family
GPY46_RS18765	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
GPY46_RS18770	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GPY46_RS18775	ENOG4105FQ6	thiopurine methyltransferase
GPY46_RS18785	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GPY46_RS18800	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GPY46_RS18805	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GPY46_RS18810	ENOG4105BZU	Histidine kinase
GPY46_RS18840	ENOG4105K8R	UPF0145 protein
GPY46_RS18845	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GPY46_RS18850	ENOG41082NX	50s ribosomal protein l35
GPY46_RS18855	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GPY46_RS18860	ENOG4105C22	threonyL-tRNA synthetase
GPY46_RS18875	ENOG4105CZE	histidine utilization repressor
GPY46_RS18880	ENOG4105CI2	imidazolone-5-propionate hydrolase
GPY46_RS18885	ENOG41088SP	formiminoglutamate hydrolase
GPY46_RS18895	ENOG4105C84	Histidine ammonia-lyase
GPY46_RS18910	ENOG4105CQB	FAD linked oxidase domain protein
GPY46_RS18925	ENOG4105CDV	Ompa motb domain protein
GPY46_RS18945	ENOG4105C8V	SAICAR synthetase
GPY46_RS18960	ENOG4105HDD	phospholipase
GPY46_RS18965	ENOG4105CQ7	ATP-dependent helicase
GPY46_RS18970	ENOG4107R1I	NAD-dependent malic enzyme
GPY46_RS18975	ENOG4107GZ4	SanA protein
GPY46_RS18980	ENOG4105C8P	)-transporter
GPY46_RS18985	ENOG4105BZU	Histidine kinase
GPY46_RS19005	ENOG4105C3M	thioredoxin reductase
GPY46_RS19010	ENOG4108JJ9	ABC, transporter
GPY46_RS19015	ENOG4108JJ8	(ABC) transporter
GPY46_RS19025	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GPY46_RS19035	ENOG4105BZU	Histidine kinase
GPY46_RS19065	ENOG4105DWU	Membrane
GPY46_RS19075	ENOG4105DY8	decarboxylase
GPY46_RS19080	ENOG4106KNT	transcriptional regulator
GPY46_RS19095	ENOG41090BQ	Glutaredoxin
GPY46_RS19100	ENOG4105D0C	transport protein
GPY46_RS19105	ENOG4105RKW	reductase (By
GPY46_RS19110	ENOG4107QPN	acyl-Coa dehydrogenase
GPY46_RS19115	ENOG41067SE	Tetr family transcriptional regulator
GPY46_RS19120	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GPY46_RS19135	ENOG4108I0Y	(ABC) transporter
GPY46_RS19140	ENOG4107QI1	Mate efflux family protein
GPY46_RS19145	ENOG4105CGD	Nad-dependent epimerase dehydratase
GPY46_RS19150	ENOG4105CUW	cytochrome C-TYPE protein
GPY46_RS19180	ENOG4105C2C	drug resistance transporter, Bcr CflA
GPY46_RS19185	ENOG4105I08	Pseudouridine synthase
GPY46_RS19190	ENOG4105CFI	type iii restriction protein res subunit
GPY46_RS19200	ENOG4105ETX	regulatoR
GPY46_RS19205	ENOG4105EB3	Histidine kinase
GPY46_RS19210	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GPY46_RS19225	ENOG4105CGH	5'-nucleotidase
GPY46_RS19240	ENOG4105XZD	Fe-S protein
GPY46_RS19250	ENOG4108ZXC	Two component transcriptional regulator, luxr family
GPY46_RS19255	ENOG4106AFQ	Histidine kinase
GPY46_RS19265	ENOG4105BZ8	glutamate synthase
GPY46_RS19275	ENOG4108RSN	SNARE associated Golgi
GPY46_RS19280	ENOG4105VNH	ABC transporter solute-binding protein
GPY46_RS19285	ENOG4105CXZ	ABC transporter, permease
GPY46_RS19290	ENOG4108VGW	abc transporter atp-binding protein
GPY46_RS19295	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
GPY46_RS19310	ENOG4108JUA	Transcriptional regulator
GPY46_RS19315	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
GPY46_RS19320	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GPY46_RS19330	ENOG4108W1A	pseudouridine synthase
GPY46_RS19340	ENOG4105C8J	)-transporter
GPY46_RS19345	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
GPY46_RS19350	ENOG4105C28	cystathionine
GPY46_RS19355	ENOG4107IFA	Lipase (EC 3.1.1.3)
GPY46_RS19365	ENOG4108R3E	Dna-3-methyladenine glycosylase i
GPY46_RS19380	ENOG410624X	efflux transporter, rnd family, mfp subunit
GPY46_RS19385	ENOG4105FM1	phage shock protein C
GPY46_RS19390	ENOG4105YYT	phage shock protein B
GPY46_RS19395	ENOG41087YS	Phage shock protein A
GPY46_RS19400	ENOG4105E51	psp operon transcriptional activator
GPY46_RS19405	ENOG4108J59	Extracellular solute-binding protein, family 5
GPY46_RS19410	ENOG4108I5W	peptide transport system, permease protein
GPY46_RS19415	ENOG4108EU3	peptide transport system, permease
GPY46_RS19420	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
GPY46_RS19425	ENOG4108JQ2	peptide transport system atp-binding protein
GPY46_RS19435	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
GPY46_RS19450	ENOG4108J2R	molybdopterin oxidoreductase
GPY46_RS19475	ENOG4105TMB	Formate nitrite transporter
GPY46_RS19500	ENOG4105GFG	DUF218 domain
GPY46_RS19505	ENOG4107104	thymidine kinase
GPY46_RS19510	ENOG4105C8N	cysteinyl-tRNA synthetase
GPY46_RS19515	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GPY46_RS19520	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GPY46_RS19525	ENOG4105D58	Diguanylate phosphodiesterase
GPY46_RS19535	ENOG4105K5B	UPF0225 protein
GPY46_RS19540	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GPY46_RS19545	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GPY46_RS19555	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GPY46_RS19560	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GPY46_RS19565	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GPY46_RS19570	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GPY46_RS19575	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GPY46_RS19580	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GPY46_RS19590	ENOG4107S6Z	Na H antiporter
GPY46_RS19595	ENOG4108YX2	DNA-binding protein
GPY46_RS19600	ENOG4107RE1	Inosine-guanosine kinase
GPY46_RS19610	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GPY46_RS19615	ENOG41075W9	High frequency lysogenization protein HflD homolog
GPY46_RS19620	ENOG4107QTF	adenylosuccinate lyase
GPY46_RS19645	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GPY46_RS19660	ENOG4107FW0	short-chain dehydrogenase reductase
GPY46_RS19670	ENOG4105D0M	Protease HtpX homolog
GPY46_RS19680	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GPY46_RS19695	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GPY46_RS19700	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
GPY46_RS19705	ENOG4105KSC	Transcriptional regulator, TraR DksA family
GPY46_RS19720	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GPY46_RS19725	ENOG4105D1H	recombination factor protein RarA
GPY46_RS19730	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
GPY46_RS19735	ENOG4105CNU	cell division protein FtsK
GPY46_RS19740	ENOG4105EW9	transcriptional regulator AsnC family
GPY46_RS19745	ENOG4105DCF	alanine dehydrogenase
GPY46_RS19755	ENOG4107R11	Transcriptional regulator
GPY46_RS19765	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
GPY46_RS19800	ENOG4105BZS	acriflavin resistance protein
GPY46_RS19805	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GPY46_RS19820	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY46_RS19845	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GPY46_RS19870	ENOG4108RNS	Exports L-alanine (By similarity)
GPY46_RS19875	ENOG4105BZU	Histidine kinase
GPY46_RS19885	ENOG4106032	Glutathionylspermidine synthase
GPY46_RS19895	ENOG4105Z6B	inner membrane protein yjfl
GPY46_RS19905	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GPY46_RS19910	ENOG4105UFD	tol-pal system protein YbgF
GPY46_RS19915	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GPY46_RS19920	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
GPY46_RS19930	ENOG4105M8F	Biopolymer transport protein exbD tolR
GPY46_RS19935	ENOG4105E02	MotA TolQ exbB proton channel
GPY46_RS19940	ENOG4107YD3	Thioesterase
GPY46_RS19955	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GPY46_RS19960	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GPY46_RS19965	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GPY46_RS19970	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GPY46_RS19975	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY46_RS19980	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GPY46_RS19985	ENOG4105C9M	aspartyl-trna synthetase
GPY46_RS19990	ENOG41081XQ	Conserved Protein
GPY46_RS19995	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
GPY46_RS20000	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
GPY46_RS20010	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY46_RS20020	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
GPY46_RS20030	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
GPY46_RS20035	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
GPY46_RS20040	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
GPY46_RS20045	ENOG4106371	Methyltransferase
GPY46_RS20050	ENOG4107S90	membrAne
GPY46_RS20055	ENOG4106WF9	DNA-binding transcriptional regulator TorR
GPY46_RS20060	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
GPY46_RS20065	ENOG4105ETE	Transcriptional regulator (LacI family
GPY46_RS20070	ENOG4105HP8	regulator of competence-specific genes
GPY46_RS20090	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GPY46_RS20095	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
GPY46_RS20100	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
GPY46_RS20105	ENOG4105RKX	Protein of unknown function (DUF2498)
GPY46_RS20110	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GPY46_RS20120	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GPY46_RS20125	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
GPY46_RS20130	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GPY46_RS20140	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GPY46_RS20145	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GPY46_RS20150	ENOG4105VEQ	Cold shock protein
GPY46_RS20160	ENOG4108R99	pseudouridine synthase
GPY46_RS20170	ENOG4105SDR	Outer membrane protein OmpT
GPY46_RS20175	ENOG4105DVT	helicase
GPY46_RS20180	ENOG4105EJ9	Membrane
GPY46_RS20185	ENOG4108URS	primosomal replication protein n''
GPY46_RS20190	ENOG4106428	Protein of unknown function (DUF2496)
GPY46_RS20195	ENOG4105CGK	Exodeoxyribonuclease III
GPY46_RS20210	ENOG4105DSP	amino acid AbC transporter
GPY46_RS20215	ENOG4105E89	ABC transporter
GPY46_RS20220	ENOG4108JEH	abc transporter atp-binding protein
GPY46_RS20240	ENOG4105C6N	Formate acetyltransferase
GPY46_RS20250	ENOG4105F1A	Pyruvate formate-lyase
GPY46_RS20260	ENOG4105XWI	UPF0304 protein
GPY46_RS20270	ENOG4105CYN	Serine protein kinase
GPY46_RS20275	ENOG4106AKX	UPF0229 protein
GPY46_RS20280	ENOG4105ED1	spovr family
GPY46_RS20285	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GPY46_RS20290	ENOG4105W49	UPF0434 protein
GPY46_RS20295	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GPY46_RS20300	ENOG4105BZ1	(ABC) transporter
GPY46_RS20305	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
GPY46_RS20315	ENOG4105D60	lipoprotein releasing system transmembrane protein
GPY46_RS20320	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GPY46_RS20325	ENOG4105D60	lipoprotein releasing system transmembrane protein
GPY46_RS20335	ENOG4108JA2	transcriptioN-repair coupling factor
GPY46_RS20350	ENOG4105CEP	NADH dehydrogenase
GPY46_RS20360	ENOG4105D0Y	UPF0227 protein
GPY46_RS20385	ENOG4105K59	histidine triad (HIT) protein
GPY46_RS20390	ENOG4108NVR	Methyl-accepting chemotaxis
GPY46_RS20405	ENOG4107SXA	Phosphorylase
GPY46_RS20415	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GPY46_RS20425	ENOG4105DZ0	fad dependent oxidoreductase
GPY46_RS20430	ENOG4108Z4U	Ferredoxin
GPY46_RS20445	ENOG4108KHX	Diguanylate cyclase
GPY46_RS20460	ENOG4108MNP	Glycoprotein polysaccharide metabolism
GPY46_RS20465	ENOG4105C29	acyl-CoA thioesterase
GPY46_RS20475	ENOG4108XM1	transcriptional regulator AsnC family
GPY46_RS20505	ENOG4105BZS	acriflavin resistance protein
GPY46_RS20510	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
GPY46_RS20555	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
GPY46_RS20560	ENOG4105HMI	Membrane
GPY46_RS20570	ENOG4105CEY	Amp-dependent synthetase and ligase
GPY46_RS20575	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
GPY46_RS20580	ENOG4108IPT	Naphthoate synthase
GPY46_RS20585	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
GPY46_RS20590	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GPY46_RS20595	ENOG4105E4F	Isochorismate synthase
GPY46_RS20600	ENOG4105CHM	Aminotransferase
GPY46_RS20605	ENOG4105DK2	UPF0207 protein
GPY46_RS20610	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GPY46_RS20625	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
GPY46_RS20630	ENOG4105EIN	peptidylprolyl cis-trans isomerase
GPY46_RS20635	ENOG4105K70	DNA-binding protein
GPY46_RS20640	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GPY46_RS20645	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GPY46_RS20650	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GPY46_RS20655	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GPY46_RS20660	ENOG4105CQZ	Histidine kinase
GPY46_RS20675	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
GPY46_RS20680	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
GPY46_RS20685	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
GPY46_RS20690	ENOG4105CNG	UPF0061 protein
GPY46_RS20715	ENOG4107ZYR	domain protein
GPY46_RS20720	ENOG4105C1J	atp-dependent rna helicase
GPY46_RS20760	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GPY46_RS20780	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GPY46_RS20785	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
GPY46_RS20790	ENOG4105C84	Histidine ammonia-lyase
GPY46_RS20815	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GPY46_RS20820	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GPY46_RS20825	ENOG4105C2D	reductase
GPY46_RS20830	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GPY46_RS20845	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GPY46_RS20850	ENOG4105D9N	nucleoside
GPY46_RS20855	ENOG4105CC0	LysR family Transcriptional regulator
GPY46_RS20860	ENOG4105CVE	Lytic murein transglycosylase
GPY46_RS20865	ENOG4105VNG	YcgL domain-containing protein
GPY46_RS20870	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GPY46_RS20875	ENOG4107QMS	site-determining protein
GPY46_RS20880	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GPY46_RS20885	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
GPY46_RS20890	ENOG4105CEY	Amp-dependent synthetase and ligase
GPY46_RS20895	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
GPY46_RS20910	ENOG41072GX	Peptidase M22 Glycoprotease
GPY46_RS20915	ENOG4105DVT	helicase
GPY46_RS20920	ENOG4105CIY	formyltetrahydrofolate deformylase
GPY46_RS20925	ENOG4106ZCM	YecM protein
GPY46_RS20935	ENOG4105C75	arginyL-tRNA synthetase
GPY46_RS20950	ENOG4105CE1	Ferrous iron transport protein b
GPY46_RS20955	ENOG4105XFK	Ferrous iron transport protein A
GPY46_RS20970	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
GPY46_RS20975	ENOG4105NXV	High-affinity zinc uptake system protein
GPY46_RS20980	ENOG4105FDK	ABC transporter
GPY46_RS20985	ENOG4105FAV	ABC, transporter
GPY46_RS20990	ENOG4105E7A	Glutamine amidotransferase
GPY46_RS20995	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GPY46_RS21000	ENOG4107QPN	acyl-Coa dehydrogenase
GPY46_RS21010	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
GPY46_RS21025	ENOG4107RZZ	dna polymerase iii epsilon subunit
GPY46_RS21030	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GPY46_RS21035	ENOG4105D1A	Methyltransferase
GPY46_RS21040	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GPY46_RS21045	ENOG4105E9H	Lytic Murein transglycosylase
GPY46_RS21055	ENOG4107NA1	Endonuclease Exonuclease phosphatase
GPY46_RS21060	ENOG4108YZA	Nitrogen regulatory protein pii
GPY46_RS21070	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GPY46_RS21075	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GPY46_RS21080	ENOG4105C0B	DNA polymerase III (alpha subunit)
GPY46_RS21090	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPY46_RS21095	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GPY46_RS21100	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GPY46_RS21105	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
GPY46_RS21115	ENOG4105DZP	Membrane-associated zinc metalloprotease
GPY46_RS21120	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GPY46_RS21125	ENOG4105KNE	Phosphatidate cytidylyltransferase
GPY46_RS21130	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GPY46_RS21135	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GPY46_RS21140	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GPY46_RS21145	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GPY46_RS21150	ENOG4105CE9	30S ribosomal protein S2
GPY46_RS21155	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GPY46_RS21160	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GPY46_RS21165	ENOG4108T8E	UPF0325 protein
GPY46_RS21170	ENOG4105DR9	pseudouridine synthase
GPY46_RS21175	ENOG4105WP7	tRNA pseudouridine synthase C
GPY46_RS21200	ENOG4108UPT	UPF0178 protein
GPY46_RS21205	ENOG4105CFC	Transporter
GPY46_RS21220	ENOG4105NRA	50s ribosomal protein l31 type b
GPY46_RS21225	ENOG4108R96	Methyltransferase, YaeB family
GPY46_RS21230	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GPY46_RS21240	ENOG4105W1I	UPF0253 protein
GPY46_RS21250	ENOG4105C8J	)-transporter
GPY46_RS21265	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GPY46_RS21270	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GPY46_RS21275	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GPY46_RS21290	ENOG4105CJ2	(LipO)protein
GPY46_RS21295	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
GPY46_RS21300	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY46_RS21305	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY46_RS21310	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY46_RS21315	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY46_RS21320	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GPY46_RS21325	ENOG4105M85	Bola protein
GPY46_RS21330	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GPY46_RS21335	ENOG4105IEY	(LipO)protein
GPY46_RS21340	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GPY46_RS21355	ENOG4105K6V	RNA polymerase
GPY46_RS21385	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
GPY46_RS21390	ENOG4107S0N	DJ-1 family
GPY46_RS21395	ENOG4105C9B	Cysteine desulfurase
GPY46_RS21400	ENOG4105BZU	Histidine kinase
GPY46_RS21405	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GPY46_RS21410	ENOG4105CUZ	uba thif-type nad fad binding protein
GPY46_RS21415	ENOG4105CA3	membrane-bound lytic murein transglycosylase
GPY46_RS21425	ENOG4107QZM	n-acetylglutamate synthase
GPY46_RS21435	ENOG4107QYX	exodeoxyribonuclease v alpha
GPY46_RS21440	ENOG4107QKA	exodeoxyribonuclease V beta
GPY46_RS21445	ENOG4105DSY	exodeoxyribonuclease V, gamma
GPY46_RS21450	ENOG4105E68	Sulfatase
GPY46_RS21460	ENOG4105EVZ	LysR family transcriptional regulator
GPY46_RS21465	ENOG4105X2V	dna damage-inducible protein
GPY46_RS21470	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
GPY46_RS21475	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
GPY46_RS21480	ENOG4105CXY	transporter
GPY46_RS21495	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
GPY46_RS21500	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GPY46_RS21505	ENOG4105E98	transcriptional regulator DeoR family
GPY46_RS21510	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
GPY46_RS21515	ENOG4107RX3	Mg2 transporter protein cora family protein
GPY46_RS21530	ENOG4108Y51	tRNA-binding protein
GPY46_RS21535	ENOG41060NJ	transcriptional regulator
GPY46_RS21540	ENOG4105CT4	transporter
GPY46_RS21550	ENOG4105ETE	Transcriptional regulator (LacI family
GPY46_RS21555	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GPY46_RS21560	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GPY46_RS21565	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
GPY46_RS21570	ENOG4105CMR	udp-glucose 4-epimerase
GPY46_RS21580	ENOG4105CQ4	Transcriptional regulator
GPY46_RS21585	ENOG4105CNT	hydrolase family 2
GPY46_RS21590	ENOG4105FK9	beta-D-galactosidase beta subunit
GPY46_RS21595	ENOG4105E5D	amino acid
GPY46_RS21600	ENOG41064T2	transcriptional regulator, lysR family
GPY46_RS21690	ENOG4108IQE	Amp-dependent synthetase and ligase
GPY46_RS21700	ENOG4105ETT	transcriptional Regulator, LysR family
GPY46_RS21705	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GPY46_RS21710	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GPY46_RS21720	ENOG4105EAC	phosphoserine phosphatase
GPY46_RS21730	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GPY46_RS21735	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
GPY46_RS21740	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
GPY46_RS21745	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GPY46_RS21750	ENOG4105D9N	nucleoside
GPY46_RS21755	ENOG4105EYA	deoxyribonuclease
GPY46_RS21765	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GPY46_RS21785	ENOG4108YYD	acetyltransferase
GPY46_RS21790	ENOG4105XPQ	lipid carrier protein
GPY46_RS21795	ENOG4105BZU	Histidine kinase
GPY46_RS21800	ENOG4105CFP	Peptidase U32
GPY46_RS21805	ENOG4106RZ4	Peptidase U32
GPY46_RS21810	ENOG4105C3S	Mate efflux family protein
GPY46_RS21825	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GPY46_RS21830	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GPY46_RS21835	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GPY46_RS21840	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GPY46_RS21845	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GPY46_RS21850	ENOG4105CHV	Transcription elongation factor NusA
GPY46_RS21855	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GPY46_RS21880	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GPY46_RS21885	ENOG4105EEI	dihydropteroate synthase
GPY46_RS21890	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GPY46_RS21895	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GPY46_RS21900	ENOG4105HBR	Rna-binding protein
GPY46_RS21905	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GPY46_RS21910	ENOG4107QE9	Inherit from COG: Membrane
GPY46_RS21915	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GPY46_RS21925	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GPY46_RS21930	ENOG4105DR5	peptidase
GPY46_RS21935	ENOG4105BZS	acriflavin resistance protein
GPY46_RS21945	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GPY46_RS21950	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
GPY46_RS21955	ENOG4105IPI	Membrane
GPY46_RS21960	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
GPY46_RS21965	ENOG4105BZU	Histidine kinase
GPY46_RS21970	ENOG4107QRA	Extracellular solute-binding protein, family 5
GPY46_RS21980	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
GPY46_RS21985	ENOG4105C3U	ABC transporter
GPY46_RS21990	ENOG4108JQ7	(ABC) transporter
GPY46_RS22000	ENOG4105RD7	BadF BadG BcrA BcrD
GPY46_RS22005	ENOG4105E2D	ec 3.2.1.52
GPY46_RS22015	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GPY46_RS22020	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GPY46_RS22040	ENOG4108YZA	Nitrogen regulatory protein pii
GPY46_RS22045	ENOG4105XTV	UPF0231 protein
GPY46_RS22050	ENOG4107QIJ	Aconitate hydratase 2
GPY46_RS22055	ENOG4105D78	K07001 NTE family protein
GPY46_RS22060	ENOG4105BZ4	penicillin-binding protein
GPY46_RS22065	ENOG4105CQ7	ATP-dependent helicase
GPY46_RS22070	ENOG4105PW4	Sugar fermentation stimulation protein homolog
GPY46_RS22075	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GPY46_RS22085	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
GPY46_RS22095	ENOG4105DJ0	Poly(A) Polymerase
GPY46_RS22100	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPY46_RS22105	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GPY46_RS22110	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GPY46_RS22115	ENOG4105D1S	lipid A biosynthesis
GPY46_RS22125	ENOG4105DA5	(ABC) transporter
GPY46_RS22135	ENOG4105CHH	sulfate transporter
GPY46_RS22140	ENOG41077A9	carbonic anhydrase
GPY46_RS22145	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
GPY46_RS22150	ENOG410630P	Transcriptional regulator
GPY46_RS22155	ENOG4107QN2	dihydrolipoyl dehydrogenase
GPY46_RS22160	ENOG4107QSN	dihydrolipoamide acetyltransferase
GPY46_RS22165	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GPY46_RS22170	ENOG41073TP	transcriptional regulator
GPY46_RS22180	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GPY46_RS22190	ENOG4107QHF	type ii secretion system protein e
GPY46_RS22195	ENOG4105D7Q	type ii secretion system
GPY46_RS22200	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
GPY46_RS22205	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GPY46_RS22210	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
GPY46_RS22215	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
GPY46_RS22220	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GPY46_RS22225	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GPY46_RS22230	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GPY46_RS22235	ENOG4105K5M	30s ribosomal protein S16
GPY46_RS22240	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPY46_RS22245	ENOG4106KVJ	cytochrome C assembly protein
GPY46_RS22250	ENOG4108JU6	CBS domain protein
GPY46_RS22255	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GPY46_RS22265	ENOG4105D9M	gamma-glutamylcysteine synthetase
GPY46_RS22275	ENOG4105W39	Membrane
GPY46_RS22280	ENOG4105CPQ	Dehydrogenase
GPY46_RS22285	ENOG4105D9Q	decarboxylase (Beta subunit)
GPY46_RS22290	ENOG4107QSA	Oxaloacetate decarboxylase
GPY46_RS22295	ENOG4106AFN	Lyase and sodium transporter (By similarity)
GPY46_RS22350	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GPY46_RS22355	ENOG4105CFH	Aspartokinase
GPY46_RS22360	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GPY46_RS22365	ENOG4105Y3E	Modulates RecA activity (By similarity)
GPY46_RS22370	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GPY46_RS22375	ENOG4107TH8	cina domain protein
GPY46_RS22380	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GPY46_RS22395	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
GPY46_RS22400	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GPY46_RS22405	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
GPY46_RS22410	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GPY46_RS22415	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GPY46_RS22420	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GPY46_RS22425	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GPY46_RS22430	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GPY46_RS22435	ENOG4105DXN	mazG family
GPY46_RS22450	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GPY46_RS22455	ENOG4105BZU	Histidine kinase
GPY46_RS22460	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GPY46_RS22465	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GPY46_RS22470	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
GPY46_RS22475	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GPY46_RS22480	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GPY46_RS22485	ENOG4105C3F	Signal peptidase i
GPY46_RS22490	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GPY46_RS22505	ENOG41069PW	sigma-e factor negative regulatory protein
GPY46_RS22510	ENOG4105EMN	RNA polymerase sigma factor
GPY46_RS22520	ENOG4108IYU	L-aspartate oxidase
GPY46_RS22530	ENOG4105Y75	tpr repeat protein
GPY46_RS22535	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GPY46_RS22550	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GPY46_RS22555	ENOG4105D0A	hydroxylase
GPY46_RS22570	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GPY46_RS22580	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GPY46_RS22585	ENOG4105E66	phosphoriboisomerase A
GPY46_RS22590	ENOG4108JQ1	Dehydrogenase
GPY46_RS22595	ENOG4105MPN	Membrane
GPY46_RS22600	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
GPY46_RS22610	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
GPY46_RS22615	ENOG4105D64	Mechanosensitive ion channel
GPY46_RS22620	ENOG4105D2N	Aldolase
GPY46_RS22625	ENOG4105BZA	Phosphoglycerate kinase
GPY46_RS22630	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GPY46_RS22635	ENOG4105D05	Receptor
GPY46_RS22640	ENOG4108R4R	Iron-regulated virulence regulatory protein
GPY46_RS22645	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GPY46_RS22655	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GPY46_RS22665	ENOG4105GPY	SprT protein
GPY46_RS22670	ENOG4105RWS	endonuclease I
GPY46_RS22675	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
GPY46_RS22680	ENOG4105D7Z	glutathione synthase
GPY46_RS22685	ENOG4108UJU	UPF0301 protein
GPY46_RS22690	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GPY46_RS22695	ENOG4105CZX	twitching motility protein
GPY46_RS22700	ENOG4105CZX	twitching motility protein
GPY46_RS22705	ENOG4105DFA	alanine racemase domain protein
GPY46_RS22710	ENOG4105II7	pyrroline-5-carboxylate reductase
GPY46_RS22715	ENOG4108VIA	integral membrane protein
GPY46_RS22720	ENOG4105VZ9	UPF0235 protein
GPY46_RS22730	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GPY46_RS22735	ENOG4105CSA	Coproporphyrinogen iii oxidase
GPY46_RS22740	ENOG4105CSV	Glutaminase
GPY46_RS22750	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GPY46_RS22755	ENOG4105CEN	a g-specific adenine glycosylase
GPY46_RS22760	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GPY46_RS22765	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
GPY46_RS22805	ENOG4105C8Q	Methyl-accepting chemotaxis
GPY46_RS22835	ENOG4105C26	Dehydrogenase
GPY46_RS22885	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
GPY46_RS22895	ENOG410901P	UPF0249 protein
GPY46_RS22900	ENOG4105F8D	glycoside hydrolase family 4
GPY46_RS22905	ENOG4105VCP	PTS System
GPY46_RS22910	ENOG4105CK1	PTS System
GPY46_RS22915	ENOG4105VZJ	PTS System
GPY46_RS22930	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
GPY46_RS22935	ENOG4105EXU	Membrane
GPY46_RS22945	ENOG4108K5H	permease YjgP YjgQ family protein
GPY46_RS22950	ENOG4108M8S	permease YjgP YjgQ family protein
GPY46_RS22955	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GPY46_RS22960	ENOG4105MYG	DNA polymerase iii, chi subunit
GPY46_RS22965	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GPY46_RS22975	ENOG4108MJ3	acetyltransferase
GPY46_RS22995	ENOG4105CEU	Arginine dihydrolase
GPY46_RS23000	ENOG4105DBV	ornithine carbamoyltransferase
GPY46_RS23010	ENOG4105CXT	aspartate transcarbamylase
GPY46_RS23015	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
GPY46_RS23020	ENOG4105KME	endoribonuclease L-psp
GPY46_RS23025	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GPY46_RS23030	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GPY46_RS23035	ENOG4105VFK	BolA family
GPY46_RS23045	ENOG4105E3I	toluene tolerance
GPY46_RS23050	ENOG4107PE3	Mammalian cell entry related domain protein
GPY46_RS23055	ENOG4105CY3	ABC transporter, permease
GPY46_RS23060	ENOG4105DHJ	ABC, transporter
GPY46_RS23070	ENOG4105C2X	Arabinose 5-phosphate isomerase
GPY46_RS23080	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
GPY46_RS23085	ENOG4108IUZ	ABC transporter
GPY46_RS23090	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPY46_RS23095	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
GPY46_RS23100	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
GPY46_RS23105	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GPY46_RS23110	ENOG41080Z8	PHOSPHOCARRIER protein
GPY46_RS23115	ENOG4105CJW	magnesium transporter
GPY46_RS23120	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GPY46_RS23125	ENOG4105N42	UPF0307 protein
GPY46_RS23130	ENOG4105C5I	Dehydrogenase
GPY46_RS23135	ENOG4105D3G	Pseudouridine synthase
GPY46_RS23145	ENOG4105K3M	)-transporter
GPY46_RS23150	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
GPY46_RS23155	ENOG4108IAB	Phoh family
GPY46_RS23160	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GPY46_RS23170	ENOG4105QD6	exported protein
GPY46_RS23175	ENOG4105C03	ribonuclease
GPY46_RS23180	ENOG4108Z03	MAF-like protein
GPY46_RS23185	ENOG4105VQ7	Rod shape-determining protein MreD
GPY46_RS23190	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GPY46_RS23195	ENOG4105DFF	Rod shape-determining protein mreb
GPY46_RS23230	ENOG4108VAU	general secretion pathway protein G
GPY46_RS23240	ENOG4105D7Q	type ii secretion system
GPY46_RS23245	ENOG4107QHF	type ii secretion system protein e
GPY46_RS23260	ENOG4105E4G	Type IV pilus
GPY46_RS23280	ENOG41062P1	Diguanylate cyclase phosphodiesterase
GPY46_RS23285	ENOG4108UUM	single-stranded DNA-binding protein
GPY46_RS23290	ENOG41086KC	Transcriptional regulator
GPY46_RS23295	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
GPY46_RS23300	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
GPY46_RS23310	ENOG4105C5R	Aminotransferase
GPY46_RS23315	ENOG4105CFH	Aspartokinase
GPY46_RS23320	ENOG4105C3R	Methionine synthase
GPY46_RS23325	ENOG4105EEQ	Na H antiporter
GPY46_RS23395	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GPY46_RS23400	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GPY46_RS23405	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GPY46_RS23430	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GPY46_RS23470	ENOG4105CVR	type I restriction-modification system
GPY46_RS23500	ENOG4105MYN	Zinc uptake regulation protein
GPY46_RS23510	ENOG4107QP8	phosphohexose isomerase
GPY46_RS23515	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GPY46_RS23525	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GPY46_RS23530	ENOG4105CDU	Replicative dna helicase
GPY46_RS23540	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GPY46_RS23545	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GPY46_RS23550	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
GPY46_RS23555	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GPY46_RS23560	ENOG4105DJV	ribulose-phosphate 3-epimerase
GPY46_RS23565	ENOG4105DFE	Dna adenine methylase
GPY46_RS23575	ENOG4105D49	3-dehydroquinate synthase
GPY46_RS23580	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GPY46_RS23585	ENOG4105E4G	Type IV pilus
GPY46_RS23610	ENOG4108JQC	penicillin-binding protein 1A
GPY46_RS23620	ENOG4105EHV	domain protein
GPY46_RS23635	ENOG4105CH7	arginosuccinase
GPY46_RS23640	ENOG4105CDH	Citrulline--aspartate ligase
GPY46_RS23645	ENOG4105CAS	nag kinase
GPY46_RS23650	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GPY46_RS23655	ENOG4105CWC	Acetylornithine deacetylase
GPY46_RS23660	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
GPY46_RS23670	ENOG4105SYT	Methylenetetrahydrofolate reductase
GPY46_RS23675	ENOG4105CFH	Aspartokinase
GPY46_RS23680	ENOG4105C28	cystathionine
GPY46_RS23685	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
GPY46_RS23690	ENOG4105C6K	Malic enzyme
GPY46_RS23695	ENOG4108UQY	Iron-storage protein
GPY46_RS23700	ENOG4105W53	bacterioferritin-associated ferredoxin
GPY46_RS23705	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GPY46_RS23710	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GPY46_RS23715	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GPY46_RS23720	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GPY46_RS23725	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GPY46_RS23730	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
GPY46_RS23735	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
GPY46_RS23740	ENOG4105WWK	YheO domain protein
GPY46_RS23745	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GPY46_RS23755	ENOG41069P5	Protein slyX homolog
GPY46_RS23760	ENOG4105D44	asparaginase
GPY46_RS23770	ENOG4108YZY	peptidylprolyl cis-trans isomerase
GPY46_RS23785	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
GPY46_RS23795	ENOG4105C5H	ABC transporter
GPY46_RS23805	ENOG4105DNZ	Alpha Beta Hydrolase
GPY46_RS23810	ENOG4105YP7	UPF0270 protein
GPY46_RS23815	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
GPY46_RS23820	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
GPY46_RS23830	ENOG4105C26	Dehydrogenase
GPY46_RS23840	ENOG4105C8Y	Acetylornithine aminotransferase
GPY46_RS23845	ENOG4105DDQ	anthranilate synthase
GPY46_RS23875	ENOG4105C31	Tryptophanyl-tRNA synthetase
GPY46_RS23880	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GPY46_RS23885	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GPY46_RS23890	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GPY46_RS23895	ENOG4105KPV	Transcriptional regulator
GPY46_RS23900	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GPY46_RS23905	ENOG4108UV7	flagellar protein motX
GPY46_RS23915	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GPY46_RS23925	ENOG4105EPW	hflc protein
GPY46_RS23930	ENOG4107QJR	hflk protein
GPY46_RS23935	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GPY46_RS23940	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GPY46_RS23945	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GPY46_RS23950	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GPY46_RS23955	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GPY46_RS23960	ENOG4105K8N	protein family UPF0079, ATPase
GPY46_RS23965	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GPY46_RS24035	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GPY46_RS24040	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GPY46_RS24045	ENOG4105DJ4	phosphatidylserine decarboxylase
GPY46_RS24050	ENOG4105C8P	)-transporter
GPY46_RS24055	ENOG4108NVR	Methyl-accepting chemotaxis
GPY46_RS24065	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GPY46_RS24070	ENOG4107YZP	Rhodanese domain protein
GPY46_RS24075	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GPY46_RS24080	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GPY46_RS24085	ENOG4105D7W	serine acetyltransferase
GPY46_RS24090	ENOG41063SB	peptidase
GPY46_RS24100	ENOG41062JF	Transcriptional regulator
GPY46_RS24110	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
GPY46_RS24125	ENOG4105E33	succinate dehydrogenase
GPY46_RS24130	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GPY46_RS24135	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
GPY46_RS24145	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GPY46_RS24150	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GPY46_RS24160	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GPY46_RS24175	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GPY46_RS24180	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GPY46_RS24185	ENOG4107QI1	Mate efflux family protein
GPY46_RS24190	ENOG4105CTQ	phosphohexokinase
GPY46_RS24195	ENOG41076HS	cation diffusion facilitator family transporter
GPY46_RS24200	ENOG4108SPG	Periplasmic Protein
GPY46_RS24205	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GPY46_RS24210	ENOG4105E0F	Histidine kinase
GPY46_RS24220	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
GPY46_RS24225	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
GPY46_RS24230	ENOG4108IJ0	Aspartate ammonia-lyase
GPY46_RS24235	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GPY46_RS24240	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GPY46_RS24250	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
GPY46_RS24260	ENOG4107QN1	sodium solute
GPY46_RS24280	ENOG4105C9Q	fumarate hydratase class II
GPY46_RS24285	ENOG4105BZU	Histidine kinase
GPY46_RS24290	ENOG4105D8G	Major Facilitator superfamily
GPY46_RS24305	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GPY46_RS24310	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GPY46_RS24315	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GPY46_RS24320	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GPY46_RS24330	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GPY46_RS24335	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GPY46_RS24340	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
GPY46_RS24345	ENOG4107XZQ	multidrug resistance protein
GPY46_RS24350	ENOG4105C5H	ABC transporter
GPY46_RS24355	ENOG4105BZU	Histidine kinase
GPY46_RS24425	ENOG4105CXN	decarboxylase
GPY46_RS24430	ENOG4105D5Q	Arginine ornithine antiporter
GPY46_RS24440	ENOG4108M3R	transcriptional activator CadC
GPY46_RS24445	ENOG4105W1Y	Transcriptional regulator
GPY46_RS24455	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GPY46_RS24465	ENOG4105C12	Phosphoribosylglycinamide synthetase
GPY46_RS24485	ENOG4105R2J	Conserved Protein
GPY46_RS24490	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
GPY46_RS24495	ENOG4108RG0	uracil-dna glycosylase
GPY46_RS24500	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GPY46_RS24515	ENOG4105E09	nadh pyrophosphatase
GPY46_RS24520	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
GPY46_RS24525	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GPY46_RS24530	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GPY46_RS24535	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GPY46_RS24540	ENOG4108VZM	50s ribosomal protein L10
GPY46_RS24545	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GPY46_RS24550	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GPY46_RS24555	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GPY46_RS24560	ENOG4105PM1	preprotein translocase subunit SecE
GPY46_RS24570	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GPY46_RS24595	ENOG4105CS9	pantothenic acid kinase
GPY46_RS24600	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GPY46_RS24605	ENOG4105D4A	Cell wall formation (By similarity)
GPY46_RS24615	ENOG4105JIM	Phosphatidylserine synthase
GPY46_RS24670	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GPY46_RS24680	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GPY46_RS24685	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
GPY46_RS24700	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
GPY46_RS24705	ENOG4107R73	Mate efflux family protein
GPY46_RS24715	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
GPY46_RS24725	ENOG4105E55	glycerol-3-phosphate acyltransferase
GPY46_RS24730	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GPY46_RS24735	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
GPY46_RS24740	ENOG4105X6C	Flagellar basal body-associated protein FliL
GPY46_RS24745	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
GPY46_RS24750	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
GPY46_RS24755	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GPY46_RS24760	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
GPY46_RS24765	ENOG4105CAK	Cell division ATP-binding protein ftsE
GPY46_RS24770	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GPY46_RS24775	ENOG4106H78	methyltransferase
GPY46_RS24785	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
GPY46_RS24840	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GPY46_RS24845	ENOG41082YX	Transcriptional regulator, arsr family
GPY46_RS24850	ENOG4105D58	Diguanylate phosphodiesterase
GPY46_RS24855	ENOG410829K	Lysine exporter protein (Lyse ygga)
GPY46_RS24860	ENOG4108EUD	Lysophospholipase
GPY46_RS24865	ENOG4105DQF	Hydrolase
GPY46_RS24880	ENOG4106IUH	DTW domain containing protein
GPY46_RS24885	ENOG4105BZU	Histidine kinase
GPY46_RS24890	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
GPY46_RS24895	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GPY46_RS24905	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GPY46_RS24910	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GPY46_RS24920	ENOG4105XQ6	frataxin-like protein
GPY46_RS24925	ENOG4107T0K	Adenylate cyclase
GPY46_RS24930	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GPY46_RS24935	ENOG41076E6	Uroporphyrinogen-III Synthase
GPY46_RS24940	ENOG4105ECF	c-methyltransferase
GPY46_RS24945	ENOG410601J	HemY protein
GPY46_RS24995	ENOG4107QK7	reductase
GPY46_RS25000	ENOG4108ZIT	Ferredoxin, 2FE-2S
GPY46_RS25005	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GPY46_RS25020	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GPY46_RS25025	ENOG4105K63	Thioredoxin
GPY46_RS25030	ENOG4105C1J	atp-dependent rna helicase
GPY46_RS25035	ENOG4105C9X	ppx gppa phosphatase
GPY46_RS25040	ENOG4105EX9	Membrane
GPY46_RS25055	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GPY46_RS25060	ENOG4105FR1	rard protein
GPY46_RS25075	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GPY46_RS25085	ENOG4105C4R	Atp-dependent dna helicase
GPY46_RS25095	ENOG4105E18	UPF0276 protein
GPY46_RS25125	ENOG4105DC7	peptidase M24
GPY46_RS25125	ENOG4105DC7	peptidase M24
GPY46_RS25130	ENOG4105D41	biosynthesis protein thiH
GPY46_RS25135	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GPY46_RS25140	ENOG4105WHD	thiamine biosynthesis protein ThiS
GPY46_RS25145	ENOG4105D06	uba thif-type nad fad binding protein
GPY46_RS25150	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GPY46_RS25155	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GPY46_RS25160	ENOG4105WMR	Protein CrcB homolog