locus-tag	class	description
A6J30_RS00015	COG3063	Type IV pilus biogenesis stability protein PilW
A6J30_RS00020	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
A6J30_RS00030	COG0531	amino acid
A6J30_RS00035	COG1560	Kdo2-lipid A biosynthetic process
A6J30_RS00040	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A6J30_RS00045	COG1280	lysine exporter protein (LysE YggA)
A6J30_RS00055	COG1115	amino acid carrier protein
A6J30_RS00080	COG1368	sulfuric ester hydrolase activity
A6J30_RS00085	COG0642	Histidine kinase
A6J30_RS00090	COG0745	RESPONSE REGULATOR receiver
A6J30_RS00100	COG1028	Short-chain dehydrogenase reductase Sdr
A6J30_RS00120	COG2113	Glycine betaine
A6J30_RS00125	COG4176	ABC-type proline glycine betaine transport system permease component
A6J30_RS00145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A6J30_RS00150	COG0456	acetyltransferase
A6J30_RS00155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A6J30_RS00160	COG0662	Cupin 2, conserved barrel domain protein
A6J30_RS00165	COG0527	aspartate kinase activity
A6J30_RS00170	COG1858	cytochrome C peroxidase
A6J30_RS00185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6J30_RS00200	COG3290	protein histidine kinase activity
A6J30_RS00205	COG4565	transcriptional regulatory protein
A6J30_RS00210	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A6J30_RS00215	COG0363	glucosamine-6-phosphate deaminase activity
A6J30_RS00220	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A6J30_RS00245	COG3284	Transcriptional regulator
A6J30_RS00250	COG1012	belongs to the aldehyde dehydrogenase family
A6J30_RS00320	COG4669	(LipO)protein
A6J30_RS00340	COG3177	Filamentation induced by cAMP protein fic
A6J30_RS00370	COG1073	alpha beta
A6J30_RS00375	COG1073	alpha beta
A6J30_RS00385	COG4792	protein secretion
A6J30_RS00390	COG4791	protein targeting
A6J30_RS00395	COG4794	Type iii secretion
A6J30_RS00400	COG4790	Type iii secretion
A6J30_RS00470	COG0457	Tetratricopeptide repeat
A6J30_RS00490	COG0730	response to heat
A6J30_RS00520	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A6J30_RS00525	COG0372	Belongs to the citrate synthase family
A6J30_RS00535	COG2828	Protein conserved in bacteria
A6J30_RS00560	COG0561	phosphatase activity
A6J30_RS00565	COG0602	queuosine metabolic process
A6J30_RS00570	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A6J30_RS00575	COG3706	GGDEF domain
A6J30_RS00615	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A6J30_RS00625	COG0840	transmembrane signaling receptor activity
A6J30_RS00630	COG1254	Belongs to the acylphosphatase family
A6J30_RS00635	COG2920	part of a sulfur-relay system
A6J30_RS00645	COG0670	Belongs to the BI1 family
A6J30_RS00650	COG1126	abc transporter atp-binding protein
A6J30_RS00655	COG0765	amino acid transport
A6J30_RS00660	COG4597	amino acid ABC transporter
A6J30_RS00665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J30_RS00680	COG1666	GTP binding
A6J30_RS00685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A6J30_RS00705	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A6J30_RS00705	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A6J30_RS00715	COG3008	intermembrane lipid transfer
A6J30_RS00720	COG2995	paraquat-inducible protein a
A6J30_RS00725	COG1132	(ABC) transporter
A6J30_RS00730	COG1956	GAF domain-containing protein
A6J30_RS00735	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
A6J30_RS00750	COG0308	aminopeptidase N
A6J30_RS00760	COG2902	Dehydrogenase
A6J30_RS00765	COG0167	dihydroorotate dehydrogenase activity
A6J30_RS00775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A6J30_RS00775	COG0116	Belongs to the methyltransferase superfamily
A6J30_RS00785	COG0488	(ABC) transporter
A6J30_RS00800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A6J30_RS00805	COG1067	ATP-dependent peptidase activity
A6J30_RS00810	COG3120	sequence-specific DNA binding
A6J30_RS01020	COG2205	protein histidine kinase activity
A6J30_RS01020	COG0784	Response regulator, receiver
A6J30_RS01035	COG3278	Belongs to the heme-copper respiratory oxidase family
A6J30_RS01050	COG2010	Cytochrome c
A6J30_RS01075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A6J30_RS01080	COG0589	response to stress
A6J30_RS01085	COG0037	tRNA processing
A6J30_RS01105	COG3842	ATPase activity
A6J30_RS01115	COG1177	transmembrane transport
A6J30_RS01125	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A6J30_RS01130	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A6J30_RS01140	COG0004	ammonium transporteR
A6J30_RS01180	COG0437	4 iron, 4 sulfur cluster binding
A6J30_RS01185	COG3383	formate dehydrogenase (NAD+) activity
A6J30_RS01185	COG0243	molybdopterin cofactor binding
A6J30_RS01215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A6J30_RS01220	COG0488	(ABC) transporter
A6J30_RS01225	COG4191	Histidine kinase
A6J30_RS01230	COG2204	response regulator
A6J30_RS01245	COG3842	ATPase activity
A6J30_RS01250	COG0746	molybdenum cofactor guanylyltransferase activity
A6J30_RS01255	COG0303	'Molybdopterin
A6J30_RS01265	COG1940	carbohydrate kinase activity
A6J30_RS01270	COG3148	PFAM DTW domain containing protein
A6J30_RS01305	COG3290	protein histidine kinase activity
A6J30_RS01305	COG0840	transmembrane signaling receptor activity
A6J30_RS01310	COG0791	NLP P60 protein
A6J30_RS01325	COG2201	protein-glutamate methylesterase activity
A6J30_RS01330	COG3001	Fructosamine kinase
A6J30_RS01340	COG0307	riboflavin synthase, alpha
A6J30_RS01345	COG0534	Mate efflux family protein
A6J30_RS01355	COG1793	dna ligase
A6J30_RS01385	COG2204	response regulator
A6J30_RS01395	COG0438	transferase activity, transferring glycosyl groups
A6J30_RS01425	COG0438	transferase activity, transferring glycosyl groups
A6J30_RS01430	COG1215	transferase activity, transferring glycosyl groups
A6J30_RS01435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A6J30_RS01445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A6J30_RS01460	COG1643	Atp-dependent helicase
A6J30_RS01465	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A6J30_RS01480	COG3302	dmso reductase anchor subunit
A6J30_RS01485	COG0437	4 iron, 4 sulfur cluster binding
A6J30_RS01490	COG0243	molybdopterin cofactor binding
A6J30_RS01520	COG3706	GGDEF domain
A6J30_RS01530	COG0443	Heat shock 70 kDa protein
A6J30_RS01535	COG0443	Heat shock 70 kDa protein
A6J30_RS01560	COG1132	(ABC) transporter
A6J30_RS01565	COG1132	(ABC) transporter
A6J30_RS01585	COG0814	amino acid
A6J30_RS01595	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A6J30_RS01675	COG1522	sequence-specific DNA binding
A6J30_RS01710	COG0515	serine threonine protein kinase
A6J30_RS01735	COG3501	Rhs element vgr protein
A6J30_RS01750	COG2204	response regulator
A6J30_RS01780	COG0739	heme binding
A6J30_RS01785	COG0861	Integral membrane protein TerC family
A6J30_RS01795	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A6J30_RS01800	COG1328	CTP reductase activity
A6J30_RS01805	COG1280	lysine exporter protein (LysE YggA)
A6J30_RS01825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J30_RS01825	COG4191	Histidine kinase
A6J30_RS01830	COG0471	metal ion transport
A6J30_RS01865	COG0583	DNA-binding transcription factor activity
A6J30_RS01870	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
A6J30_RS01875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A6J30_RS01880	COG3264	Mechanosensitive ion channel
A6J30_RS01880	COG1511	domain protein
A6J30_RS01895	COG1127	ABC transporter
A6J30_RS01900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A6J30_RS01960	COG0625	glutathione transferase activity
A6J30_RS01970	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
A6J30_RS01985	COG2195	Cleaves the N-terminal amino acid of tripeptides
A6J30_RS01995	COG0601	transmembrane transport
A6J30_RS02000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6J30_RS02005	COG0444	Belongs to the ABC transporter superfamily
A6J30_RS02020	COG3291	Pkd domain containing protein
A6J30_RS02035	COG1177	transmembrane transport
A6J30_RS02040	COG1176	ABC-type spermidine putrescine transport system, permease component I
A6J30_RS02045	COG3842	ATPase activity
A6J30_RS02050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A6J30_RS02055	COG2423	ornithine cyclodeaminase activity
A6J30_RS02070	COG3938	Belongs to the proline racemase family
A6J30_RS02100	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
A6J30_RS02105	COG1451	nucleotide metabolic process
A6J30_RS02110	COG3475	LICD family
A6J30_RS02120	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A6J30_RS02140	COG0583	DNA-binding transcription factor activity
A6J30_RS02160	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
A6J30_RS02165	COG4139	cobalamin transport
A6J30_RS02170	COG2988	succinylglutamate desuccinylase activity
A6J30_RS02195	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A6J30_RS02200	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A6J30_RS02205	COG0702	epimerase
A6J30_RS02210	COG1823	symporter activity
A6J30_RS02215	COG2925	Exonuclease
A6J30_RS02220	COG1380	Effector of murein hydrolase LrgA
A6J30_RS02225	COG1346	cytolysis
A6J30_RS02230	COG0295	cytidine deaminase activity
A6J30_RS02235	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A6J30_RS02240	COG0500	methyltransferase
A6J30_RS02250	COG0776	regulation of translation
A6J30_RS02260	COG0072	phenylalanine-tRNA ligase activity
A6J30_RS02260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J30_RS02265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A6J30_RS02270	COG3706	GGDEF domain
A6J30_RS02300	COG0393	Putative heavy-metal-binding
A6J30_RS02310	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A6J30_RS02320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A6J30_RS02335	COG2188	Transcriptional regulator
A6J30_RS02340	COG1228	amidohydrolase
A6J30_RS02345	COG0010	Belongs to the arginase family
A6J30_RS02350	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
A6J30_RS02355	COG2986	histidine ammonia-lyase
A6J30_RS02370	COG0277	FAD linked oxidase domain protein
A6J30_RS02370	COG0247	lactate metabolic process
A6J30_RS02405	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A6J30_RS02420	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
A6J30_RS02425	COG1643	Atp-dependent helicase
A6J30_RS02430	COG0281	malic enzyme
A6J30_RS02435	COG2949	membrane
A6J30_RS02440	COG0471	metal ion transport
A6J30_RS02465	COG0492	ferredoxin-NADP+ reductase activity
A6J30_RS02470	COG4988	ABC transporter
A6J30_RS02475	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A6J30_RS02480	COG3048	D-serine ammonia-lyase activity
A6J30_RS02485	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
A6J30_RS02495	COG4191	Histidine kinase
A6J30_RS02495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J30_RS02510	COG3070	regulator of competence-specific genes
A6J30_RS02530	COG2431	L-lysine efflux transmembrane transporter activity
A6J30_RS02540	COG0076	glutamate decarboxylase activity
A6J30_RS02545	COG1737	Transcriptional regulator
A6J30_RS02555	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A6J30_RS02560	COG3273	potassium ion transport
A6J30_RS02560	COG2985	domain, Protein
A6J30_RS02565	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A6J30_RS02580	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A6J30_RS02595	COG4181	ATPase activity
A6J30_RS02600	COG0534	Mate efflux family protein
A6J30_RS02605	COG0702	epimerase
A6J30_RS02640	COG2814	Major facilitator Superfamily
A6J30_RS02645	COG1187	pseudouridine synthase activity
A6J30_RS02650	COG1061	Type III restriction enzyme res subunit
A6J30_RS02670	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A6J30_RS02695	COG3313	Fe-S protein
A6J30_RS02720	COG0493	'glutamate synthase
A6J30_RS02730	COG0398	Pfam SNARE associated Golgi protein
A6J30_RS02735	COG4134	Bacterial extracellular solute-binding protein
A6J30_RS02740	COG4135	transport system, permease component
A6J30_RS02745	COG4136	ATPase activity
A6J30_RS02750	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A6J30_RS02760	COG3604	Transcriptional regulator
A6J30_RS02765	COG1151	hydroxylamine reductase activity
A6J30_RS02770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A6J30_RS02780	COG0564	pseudouridine synthase activity
A6J30_RS02790	COG0733	neurotransmitter:sodium symporter activity
A6J30_RS02800	COG0626	cystathionine gamma-synthase activity
A6J30_RS02805	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
A6J30_RS02810	COG5380	lipid catabolic process
A6J30_RS02815	COG2818	Glycosylase
A6J30_RS02830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6J30_RS02835	COG1983	PspC domain protein
A6J30_RS02845	COG1842	Phage shock protein A
A6J30_RS02850	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A6J30_RS02865	COG4171	peptide transport system, permease
A6J30_RS02875	COG4172	Belongs to the ABC transporter superfamily
A6J30_RS02885	COG1227	inorganic diphosphatase activity
A6J30_RS02900	COG0243	molybdopterin cofactor binding
A6J30_RS02905	COG3005	denitrification pathway
A6J30_RS02910	COG4459	periplasmic nitrate reductase
A6J30_RS02915	COG0390	transport system, permease component
A6J30_RS02925	COG2116	formate transmembrane transporter activity
A6J30_RS02950	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A6J30_RS02955	COG1435	thymidine kinase activity
A6J30_RS02960	COG0215	cysteine-tRNA ligase activity
A6J30_RS02965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A6J30_RS02975	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
A6J30_RS02980	COG3012	SEC-C Motif Domain Protein
A6J30_RS02985	COG0140	phosphoribosyl-ATP diphosphatase activity
A6J30_RS02985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A6J30_RS02990	COG0107	imidazoleglycerol-phosphate synthase activity
A6J30_RS02995	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A6J30_RS03000	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A6J30_RS03005	COG0131	Imidazoleglycerol-phosphate dehydratase
A6J30_RS03005	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A6J30_RS03010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A6J30_RS03015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A6J30_RS03020	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A6J30_RS03035	COG1757	Na H antiporter
A6J30_RS03045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A6J30_RS03055	COG0482	sulfurtransferase activity
A6J30_RS03060	COG2915	High frequency lysogenization protein hflD homolog
A6J30_RS03065	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A6J30_RS03090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A6J30_RS03105	COG0300	oxidoreductase activity
A6J30_RS03115	COG0501	Belongs to the peptidase M48B family
A6J30_RS03125	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A6J30_RS03135	COG0156	8-amino-7-oxononanoate synthase activity
A6J30_RS03140	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A6J30_RS03150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A6J30_RS03165	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A6J30_RS03170	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A6J30_RS03175	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A6J30_RS03180	COG1674	ftsk spoiiie
A6J30_RS03190	COG0686	Belongs to the AlaDH PNT family
A6J30_RS03200	COG0583	DNA-binding transcription factor activity
A6J30_RS03215	COG3568	Endonuclease Exonuclease Phosphatase
A6J30_RS03245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A6J30_RS03250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6J30_RS03260	COG0840	transmembrane signaling receptor activity
A6J30_RS03320	COG0582	viral genome integration into host DNA
A6J30_RS03370	COG5002	protein histidine kinase activity
A6J30_RS03370	COG0784	Response regulator, receiver
A6J30_RS03380	COG0754	glutathionylspermidine amidase activity
A6J30_RS03390	COG3766	membrane
A6J30_RS03400	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A6J30_RS03405	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
A6J30_RS03410	COG2885	chlorophyll binding
A6J30_RS03415	COG0823	Involved in the tonB-independent uptake of proteins
A6J30_RS03430	COG0811	peptide transport
A6J30_RS03435	COG0824	Thioesterase
A6J30_RS03445	COG4890	Cyd operon protein YbgT
A6J30_RS03450	COG1294	oxidase, subunit
A6J30_RS03455	COG1271	oxidase subunit
A6J30_RS03460	COG2255	four-way junction helicase activity
A6J30_RS03465	COG0632	four-way junction helicase activity
A6J30_RS03470	COG0840	transmembrane signaling receptor activity
A6J30_RS03475	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
A6J30_RS03480	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A6J30_RS03485	COG1801	Protein of unknown function DUF72
A6J30_RS03490	COG4106	trans-aconitate 2-methyltransferase activity
A6J30_RS03495	COG0500	methyltransferase
A6J30_RS03505	COG0189	ligase activity
A6J30_RS03505	COG4067	protein conserved in archaea
A6J30_RS03525	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
A6J30_RS03530	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
A6J30_RS03535	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
A6J30_RS03545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A6J30_RS03550	COG0745	RESPONSE REGULATOR receiver
A6J30_RS03555	COG3381	protein complex oligomerization
A6J30_RS03560	COG1609	Transcriptional regulator
A6J30_RS03565	COG3070	regulator of competence-specific genes
A6J30_RS03585	COG0297	glycogen (starch) synthase activity
A6J30_RS03590	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A6J30_RS03605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A6J30_RS03615	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
A6J30_RS03620	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
A6J30_RS03625	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A6J30_RS03635	COG0542	response to heat
A6J30_RS03640	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
A6J30_RS03645	COG1278	Cold shock
A6J30_RS03655	COG1187	pseudouridine synthase activity
A6J30_RS03660	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
A6J30_RS03670	COG1199	ATP-dependent helicase activity
A6J30_RS03675	COG0730	response to heat
A6J30_RS03680	COG3923	Primosomal replication protein n
A6J30_RS03690	COG0708	Exodeoxyribonuclease III
A6J30_RS03730	COG1882	Formate acetyltransferase
A6J30_RS03740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A6J30_RS03750	COG3013	Belongs to the UPF0304 family
A6J30_RS03755	COG2766	serine protein kinase
A6J30_RS03760	COG2718	Belongs to the UPF0229 family
A6J30_RS03765	COG2719	SpoVR family
A6J30_RS03770	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
A6J30_RS03780	COG1663	tetraacyldisaccharide 4'-kinase activity
A6J30_RS03785	COG1132	(ABC) transporter
A6J30_RS03790	COG2333	competence protein COMEC
A6J30_RS03790	COG0658	competence protein
A6J30_RS03800	COG4591	ABC-type transport system involved in lipoprotein release permease component
A6J30_RS03805	COG1136	(ABC) transporter
A6J30_RS03810	COG4591	ABC-type transport system involved in lipoprotein release permease component
A6J30_RS03820	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A6J30_RS03835	COG1252	NADH dehydrogenase
A6J30_RS03840	COG3150	esterase
A6J30_RS03865	COG0537	adenosine 5'-monophosphoramidase activity
A6J30_RS03890	COG0516	GMP reductase activity
A6J30_RS03890	COG0517	IMP dehydrogenase activity
A6J30_RS03900	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
A6J30_RS03905	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A6J30_RS03910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A6J30_RS03920	COG2199	diguanylate cyclase activity
A6J30_RS03935	COG3126	Type III secretion system lipoprotein chaperone (YscW)
A6J30_RS03940	COG1946	Acyl-CoA thioesterase
A6J30_RS03950	COG1522	sequence-specific DNA binding
A6J30_RS03975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A6J30_RS04025	COG0477	Major facilitator Superfamily
A6J30_RS04030	COG2855	membrane
A6J30_RS04050	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A6J30_RS04055	COG0596	Alpha beta hydrolase
A6J30_RS04060	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
A6J30_RS04065	COG1169	isochorismate synthase
A6J30_RS04070	COG0436	Aminotransferase
A6J30_RS04075	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
A6J30_RS04080	COG0232	Belongs to the dGTPase family. Type 2 subfamily
A6J30_RS04095	COG1555	photosystem II stabilization
A6J30_RS04100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A6J30_RS04105	COG0776	regulation of translation
A6J30_RS04110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A6J30_RS04115	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A6J30_RS04120	COG0740	serine-type endopeptidase activity
A6J30_RS04125	COG0544	peptidyl-prolyl cis-trans isomerase activity
A6J30_RS04140	COG2204	response regulator
A6J30_RS04150	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A6J30_RS04155	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A6J30_RS04160	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A6J30_RS04165	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
A6J30_RS04185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A6J30_RS04190	COG0569	domain protein
A6J30_RS04195	COG0513	Belongs to the DEAD box helicase family
A6J30_RS04200	COG1253	flavin adenine dinucleotide binding
A6J30_RS04235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A6J30_RS04240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A6J30_RS04255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A6J30_RS04260	COG1216	Glycosyl transferase, family 2
A6J30_RS04265	COG2986	histidine ammonia-lyase
A6J30_RS04290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A6J30_RS04300	COG1028	Short-chain dehydrogenase reductase Sdr
A6J30_RS04305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A6J30_RS04320	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A6J30_RS04325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A6J30_RS04330	COG0583	DNA-binding transcription factor activity
A6J30_RS04335	COG2951	lytic endotransglycosylase activity
A6J30_RS04340	COG3100	YcgL domain-containing protein
A6J30_RS04345	COG0850	regulation of cytokinetic process
A6J30_RS04350	COG2894	cell division
A6J30_RS04355	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
A6J30_RS04360	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A6J30_RS04365	COG0318	PFAM AMP-dependent synthetase and ligase
A6J30_RS04370	COG2267	carboxylic ester hydrolase activity
A6J30_RS04385	COG1214	PFAM Peptidase M22, glycoprotease
A6J30_RS04390	COG1199	ATP-dependent helicase activity
A6J30_RS04395	COG0788	formyltetrahydrofolate deformylase activity
A6J30_RS04400	COG3102	Protein conserved in bacteria
A6J30_RS04405	COG0018	arginyl-trna synthetase
A6J30_RS04425	COG1918	ferrous iron import across plasma membrane
A6J30_RS04435	COG4977	sequence-specific DNA binding
A6J30_RS04440	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
A6J30_RS04445	COG1121	(ABC) transporter
A6J30_RS04450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A6J30_RS04460	COG0045	succinate-CoA ligase (ADP-forming) activity
A6J30_RS04470	COG0567	Dehydrogenase, E1 component
A6J30_RS04475	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A6J30_RS04480	COG1053	succinate dehydrogenase
A6J30_RS04485	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A6J30_RS04500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A6J30_RS04510	COG0033	Phosphoglucomutase
A6J30_RS04515	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
A6J30_RS04520	COG0596	Alpha beta hydrolase
A6J30_RS04540	COG0735	belongs to the Fur family
A6J30_RS04545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A6J30_RS04560	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A6J30_RS04565	COG1846	Transcriptional regulator
A6J30_RS04565	COG1940	carbohydrate kinase activity
A6J30_RS04570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A6J30_RS04570	COG4651	solute:proton antiporter activity
A6J30_RS04575	COG0367	asparagine synthase
A6J30_RS04580	COG0250	Participates in transcription elongation, termination and antitermination
A6J30_RS04585	COG3104	oligopeptide transport
A6J30_RS04590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
A6J30_RS04595	COG0563	adenylate kinase activity
A6J30_RS04600	COG0326	Molecular chaperone. Has ATPase activity
A6J30_RS04605	COG3710	Transcriptional regulator
A6J30_RS04625	COG0622	Phosphoesterase
A6J30_RS04655	COG1090	epimerase
A6J30_RS04660	COG0300	oxidoreductase activity
A6J30_RS04665	COG3118	belongs to the thioredoxin family
A6J30_RS04670	COG0330	HflC and HflK could
A6J30_RS04690	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A6J30_RS04695	COG3115	cell septum assembly
A6J30_RS04700	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
A6J30_RS04705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A6J30_RS04715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6J30_RS04720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A6J30_RS04725	COG2190	(PTS) system
A6J30_RS04730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J30_RS04735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J30_RS04745	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J30_RS04750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J30_RS04760	COG1705	Flagellar rod assembly protein muramidase FlgJ
A6J30_RS04760	COG3951	Flagellar rod assembly protein muramidase FlgJ
A6J30_RS04765	COG1706	bacterial-type flagellum-dependent cell motility
A6J30_RS04770	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
A6J30_RS04780	COG4787	bacterial-type flagellum-dependent cell motility
A6J30_RS04790	COG1749	Flagellar hook protein flgE
A6J30_RS04800	COG1558	bacterial-type flagellum-dependent cell motility
A6J30_RS04805	COG1815	bacterial-type flagellum-dependent cell motility
A6J30_RS04810	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A6J30_RS04815	COG0784	Response regulator, receiver
A6J30_RS04815	COG0835	chemotaxis
A6J30_RS04865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A6J30_RS04870	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
A6J30_RS04885	COG2217	Heavy metal translocating P-type atpase
A6J30_RS04885	COG2608	mercury ion transmembrane transporter activity
A6J30_RS04920	COG2840	Smr protein MutS2
A6J30_RS04925	COG1187	pseudouridine synthase activity
A6J30_RS04935	COG0737	Belongs to the 5'-nucleotidase family
A6J30_RS04940	COG2877	3-deoxy-8-phosphooctulonate synthase activity
A6J30_RS04945	COG2912	Transglutaminase-like superfamily
A6J30_RS04950	COG3094	Invasion gene expression up-regulator, SirB
A6J30_RS04955	COG2890	protein-(glutamine-N5) methyltransferase activity
A6J30_RS04960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A6J30_RS04965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
A6J30_RS04970	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
A6J30_RS04975	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A6J30_RS04980	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A6J30_RS04985	COG0193	aminoacyl-tRNA hydrolase activity
A6J30_RS04990	COG0012	GTP binding
A6J30_RS05105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A6J30_RS05110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A6J30_RS05115	COG1702	phosphate starvation-inducible protein PhoH
A6J30_RS05120	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A6J30_RS05125	COG4535	Mg2 and Co2 transporter CorC
A6J30_RS05130	COG0815	Transfers the fatty acyl group on membrane lipoproteins
A6J30_RS05135	COG2888	peptidyl-tyrosine sulfation
A6J30_RS05140	COG0495	leucyl-tRNA aminoacylation
A6J30_RS05145	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
A6J30_RS05150	COG1466	dna polymerase III delta subunit
A6J30_RS05155	COG0799	negative regulation of ribosome biogenesis
A6J30_RS05160	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
A6J30_RS05165	COG0768	penicillin binding
A6J30_RS05170	COG0772	Belongs to the SEDS family
A6J30_RS05175	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A6J30_RS05180	COG1686	Belongs to the peptidase S11 family
A6J30_RS05185	COG2921	Belongs to the UPF0250 family
A6J30_RS05190	COG0321	lipoyl(octanoyl) transferase activity
A6J30_RS05195	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A6J30_RS05200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A6J30_RS05205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J30_RS05220	COG0366	Alpha amylase catalytic
A6J30_RS05225	COG1263	PTS System
A6J30_RS05225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J30_RS05235	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A6J30_RS05245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A6J30_RS05250	COG2011	ABC-type metal ion transport system permease component
A6J30_RS05255	COG1464	Belongs to the NlpA lipoprotein family
A6J30_RS05260	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
A6J30_RS05270	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
A6J30_RS05270	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
A6J30_RS05285	COG1611	Belongs to the LOG family
A6J30_RS05290	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A6J30_RS05300	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
A6J30_RS05315	COG0583	DNA-binding transcription factor activity
A6J30_RS05320	COG0301	tRNA thio-modification
A6J30_RS05320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A6J30_RS05330	COG2885	chlorophyll binding
A6J30_RS05335	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A6J30_RS05340	COG1722	exodeoxyribonuclease VII activity
A6J30_RS05345	COG0142	geranyltranstransferase activity
A6J30_RS05350	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A6J30_RS05355	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A6J30_RS05360	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A6J30_RS05365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A6J30_RS05385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A6J30_RS05385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A6J30_RS05390	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A6J30_RS05395	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A6J30_RS05410	COG1073	alpha beta
A6J30_RS05415	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
A6J30_RS05420	COG2252	PERMEase
A6J30_RS05425	COG2195	Cleaves the N-terminal amino acid of tripeptides
A6J30_RS05450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A6J30_RS05450	COG0047	phosphoribosylformylglycinamidine synthase activity
A6J30_RS05455	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
A6J30_RS05470	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A6J30_RS05505	COG0484	heat shock protein binding
A6J30_RS05510	COG0443	Heat shock 70 kDa protein
A6J30_RS05520	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A6J30_RS05525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A6J30_RS05535	COG0497	DNA recombination
A6J30_RS05540	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A6J30_RS05545	COG2914	Belongs to the UPF0125 (RnfH) family
A6J30_RS05550	COG2867	negative regulation of translational initiation
A6J30_RS05555	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A6J30_RS05570	COG0328	RNA-DNA hybrid ribonuclease activity
A6J30_RS05605	COG0583	DNA-binding transcription factor activity
A6J30_RS05610	COG3153	acetyltransferase
A6J30_RS05610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A6J30_RS05630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A6J30_RS05635	COG2873	o-acetylhomoserine
A6J30_RS05670	COG1115	amino acid carrier protein
A6J30_RS05680	COG1584	GPR1 FUN34 yaaH family protein
A6J30_RS05690	COG1757	Na H antiporter
A6J30_RS05695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A6J30_RS05695	COG0519	Catalyzes the synthesis of GMP from XMP
A6J30_RS05700	COG0517	IMP dehydrogenase activity
A6J30_RS05700	COG0516	GMP reductase activity
A6J30_RS05705	COG1570	exodeoxyribonuclease VII activity
A6J30_RS05720	COG1160	GTP binding
A6J30_RS05725	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A6J30_RS05730	COG2976	Protein conserved in bacteria
A6J30_RS05735	COG0124	histidyl-tRNA synthetase
A6J30_RS05740	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
A6J30_RS05750	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A6J30_RS05755	COG0105	UTP biosynthetic process
A6J30_RS05760	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A6J30_RS05765	COG2975	iron-sulfur cluster assembly
A6J30_RS05770	COG0633	Ferredoxin
A6J30_RS05775	COG0443	Heat shock 70 kDa protein
A6J30_RS05780	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
A6J30_RS05790	COG0822	iron-sulfur transferase activity
A6J30_RS05795	COG1104	cysteine desulfurase activity
A6J30_RS05800	COG1959	2 iron, 2 sulfur cluster binding
A6J30_RS05810	COG0483	inositol monophosphate 1-phosphatase activity
A6J30_RS05815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A6J30_RS05820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A6J30_RS05825	COG1862	Preprotein translocase
A6J30_RS05830	COG0343	queuine tRNA-ribosyltransferase activity
A6J30_RS05835	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A6J30_RS05850	COG0517	IMP dehydrogenase activity
A6J30_RS05860	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A6J30_RS05865	COG0583	DNA-binding transcription factor activity
A6J30_RS05870	COG0450	alkyl hydroperoxide reductase
A6J30_RS05880	COG3142	Participates in the control of copper homeostasis
A6J30_RS05890	COG0704	Plays a role in the regulation of phosphate uptake
A6J30_RS05895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A6J30_RS05900	COG0581	inorganic phosphate transmembrane transporter activity
A6J30_RS05910	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A6J30_RS05915	COG0248	Ppx GppA phosphatase
A6J30_RS05925	COG5002	protein histidine kinase activity
A6J30_RS05930	COG0745	RESPONSE REGULATOR receiver
A6J30_RS05940	COG2974	May be involved in recombination
A6J30_RS05945	COG0826	peptidase U32
A6J30_RS05950	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A6J30_RS06020	COG0564	pseudouridine synthase activity
A6J30_RS06025	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A6J30_RS06030	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
A6J30_RS06035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A6J30_RS06040	COG1605	Chorismate mutase
A6J30_RS06040	COG0077	Prephenate dehydratase
A6J30_RS06045	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
A6J30_RS06050	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
A6J30_RS06060	COG0488	(ABC) transporter
A6J30_RS06075	COG0739	heme binding
A6J30_RS06080	COG1605	Chorismate mutase
A6J30_RS06080	COG0287	Prephenate dehydrogenase
A6J30_RS06085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A6J30_RS06090	COG1472	Belongs to the glycosyl hydrolase 3 family
A6J30_RS06095	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
A6J30_RS06100	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A6J30_RS06115	COG1966	Carbon starvation protein
A6J30_RS06120	COG3275	phosphorelay sensor kinase activity
A6J30_RS06125	COG3279	Response regulator of the LytR AlgR family
A6J30_RS06130	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A6J30_RS06135	COG1047	Peptidyl-prolyl cis-trans
A6J30_RS06140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A6J30_RS06145	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A6J30_RS06150	COG0196	riboflavin kinase activity
A6J30_RS06155	COG0728	peptidoglycan biosynthetic process
A6J30_RS06160	COG0268	Binds directly to 16S ribosomal RNA
A6J30_RS06170	COG0640	Transcriptional regulator
A6J30_RS06175	COG0583	DNA-binding transcription factor activity
A6J30_RS06180	COG1283	sodium-dependent phosphate transmembrane transporter activity
A6J30_RS06190	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
A6J30_RS06195	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A6J30_RS06200	COG0730	response to heat
A6J30_RS06210	COG0494	nUDIX hydrolase
A6J30_RS06220	COG3066	DNA modification
A6J30_RS06230	COG0667	Aldo Keto reductase
A6J30_RS06245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A6J30_RS06250	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A6J30_RS06255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A6J30_RS06260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A6J30_RS06265	COG4974	Belongs to the 'phage' integrase family
A6J30_RS06270	COG0716	FMN binding
A6J30_RS06280	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A6J30_RS06285	COG0513	Belongs to the DEAD box helicase family
A6J30_RS06290	COG3022	response to hydroperoxide
A6J30_RS06295	COG1115	amino acid carrier protein
A6J30_RS06310	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A6J30_RS06320	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
A6J30_RS06325	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
A6J30_RS06330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A6J30_RS06335	COG0083	homoserine kinase activity
A6J30_RS06355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A6J30_RS06370	COG0745	RESPONSE REGULATOR receiver
A6J30_RS06380	COG2198	Histidine kinase
A6J30_RS06380	COG5002	protein histidine kinase activity
A6J30_RS06380	COG0784	Response regulator, receiver
A6J30_RS06385	COG5001	Diguanylate cyclase
A6J30_RS06385	COG4251	negative regulation of phosphorylation
A6J30_RS06385	COG2203	Gaf domain
A6J30_RS06385	COG3706	GGDEF domain
A6J30_RS06390	COG1242	4 iron, 4 sulfur cluster binding
A6J30_RS06395	COG0069	glutamate synthase activity
A6J30_RS06395	COG0070	glutamate synthase
A6J30_RS06395	COG0067	glutamate synthase
A6J30_RS06405	COG0067	glutamate synthase
A6J30_RS06405	COG0069	glutamate synthase activity
A6J30_RS06405	COG0070	glutamate synthase
A6J30_RS06410	COG0493	'glutamate synthase
A6J30_RS06420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A6J30_RS06430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A6J30_RS06435	COG2860	membrane
A6J30_RS06440	COG0583	DNA-binding transcription factor activity
A6J30_RS06445	COG0730	response to heat
A6J30_RS06460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A6J30_RS06465	COG0505	Belongs to the CarA family
A6J30_RS06470	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A6J30_RS06475	COG0494	nUDIX hydrolase
A6J30_RS06480	COG0653	protein targeting
A6J30_RS06490	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
A6J30_RS06495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A6J30_RS06500	COG0849	cell division
A6J30_RS06505	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A6J30_RS06510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A6J30_RS06515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A6J30_RS06520	COG0772	Belongs to the SEDS family
A6J30_RS06525	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A6J30_RS06530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A6J30_RS06535	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A6J30_RS06540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A6J30_RS06545	COG0768	penicillin binding
A6J30_RS06550	COG3116	cell division
A6J30_RS06555	COG0275	rRNA processing
A6J30_RS06580	COG0792	nuclease activity
A6J30_RS06585	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
A6J30_RS06590	COG2823	Periplasmic or secreted lipoprotein
A6J30_RS06595	COG2969	positive regulation of protein catabolic process
A6J30_RS06600	COG0625	glutathione transferase activity
A6J30_RS06605	COG2857	Cytochrome c1
A6J30_RS06610	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A6J30_RS06615	COG0723	plastoquinol--plastocyanin reductase activity
A6J30_RS06620	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A6J30_RS06625	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A6J30_RS06635	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A6J30_RS06640	COG3105	Protein conserved in bacteria
A6J30_RS06650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A6J30_RS06655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A6J30_RS06665	COG3150	esterase
A6J30_RS06675	COG3151	Protein conserved in bacteria
A6J30_RS06680	COG0494	nUDIX hydrolase
A6J30_RS06685	COG1538	Outer membrane efflux protein
A6J30_RS06690	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A6J30_RS06690	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A6J30_RS06695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
A6J30_RS06710	COG3025	triphosphatase activity
A6J30_RS06715	COG1392	Phosphate transport regulator
A6J30_RS06720	COG0306	phosphate transporter
A6J30_RS06725	COG4991	sh3 domain protein
A6J30_RS06735	COG3409	Peptidoglycan-binding domain 1 protein
A6J30_RS06735	COG3267	Type II secretory pathway component ExeA
A6J30_RS06740	COG0617	tRNA 3'-terminal CCA addition
A6J30_RS06745	COG1968	undecaprenyl-diphosphatase activity
A6J30_RS06750	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A6J30_RS06755	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A6J30_RS06760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A6J30_RS06765	COG0596	Alpha beta hydrolase
A6J30_RS06770	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A6J30_RS06775	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A6J30_RS06780	COG1610	YqeY-like protein
A6J30_RS06785	COG0358	DNA primase activity
A6J30_RS06805	COG3550	peptidyl-serine autophosphorylation
A6J30_RS06880	COG0732	type I restriction modification DNA specificity domain
A6J30_RS06915	COG1464	Belongs to the NlpA lipoprotein family
A6J30_RS06925	COG2207	Transcriptional regulator
A6J30_RS06960	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6J30_RS06960	COG2213	PTS system mannitol-specific
A6J30_RS06965	COG0246	Mannitol dehydrogenase
A6J30_RS06970	COG3722	fumarate hydratase activity
A6J30_RS06985	COG1461	Dihydroxyacetone kinase
A6J30_RS06990	COG2376	Dihydroxyacetone kinase
A6J30_RS07000	COG5002	protein histidine kinase activity
A6J30_RS07015	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A6J30_RS07020	COG1349	DNA-binding transcription factor activity
A6J30_RS07025	COG0469	pyruvate kinase activity
A6J30_RS07040	COG0440	acetolactate synthase activity
A6J30_RS07045	COG0028	Belongs to the TPP enzyme family
A6J30_RS07050	COG1022	Amp-dependent synthetase and ligase
A6J30_RS07055	COG0583	DNA-binding transcription factor activity
A6J30_RS07075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A6J30_RS07080	COG0473	3-isopropylmalate dehydrogenase activity
A6J30_RS07085	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A6J30_RS07090	COG0066	3-isopropylmalate dehydratase activity
A6J30_RS07100	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
A6J30_RS07105	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A6J30_RS07110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A6J30_RS07115	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A6J30_RS07120	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A6J30_RS07125	COG2967	ApaG domain
A6J30_RS07145	COG2966	Psort location CytoplasmicMembrane, score
A6J30_RS07150	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A6J30_RS07160	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A6J30_RS07165	COG0142	geranyltranstransferase activity
A6J30_RS07175	COG0039	L-malate dehydrogenase activity
A6J30_RS07190	COG2358	TRAP transporter, solute receptor (TAXI family
A6J30_RS07210	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
A6J30_RS07215	COG1178	ABC-type Fe3 transport system permease component
A6J30_RS07225	COG0163	prenyltransferase activity
A6J30_RS07230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A6J30_RS07235	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
A6J30_RS07240	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A6J30_RS07250	COG2105	PFAM AIG2 family protein
A6J30_RS07265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6J30_RS07275	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
A6J30_RS07290	COG4181	ATPase activity
A6J30_RS07310	COG0529	Catalyzes the synthesis of activated sulfate
A6J30_RS07315	COG3273	potassium ion transport
A6J30_RS07315	COG0471	metal ion transport
A6J30_RS07320	COG2895	sulfate adenylyltransferase (ATP) activity
A6J30_RS07325	COG0175	sulfate reduction
A6J30_RS07330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A6J30_RS07330	COG1648	precorrin-2 dehydrogenase activity
A6J30_RS07345	COG0513	Belongs to the DEAD box helicase family
A6J30_RS07350	COG2153	protein acetylation
A6J30_RS07360	COG0545	Peptidyl-prolyl cis-trans isomerase
A6J30_RS07370	COG0203	ribosomal protein L17
A6J30_RS07375	COG0202	RNA polymerase activity
A6J30_RS07385	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A6J30_RS07390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A6J30_RS07395	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A6J30_RS07400	COG0201	protein transport
A6J30_RS07405	COG0200	Binds to the 23S rRNA
A6J30_RS07410	COG1841	ribosomal large subunit assembly
A6J30_RS07425	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A6J30_RS07430	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A6J30_RS07435	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A6J30_RS07440	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A6J30_RS07445	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A6J30_RS07450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A6J30_RS07455	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A6J30_RS07460	COG0255	Belongs to the universal ribosomal protein uL29 family
A6J30_RS07470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A6J30_RS07475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A6J30_RS07480	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A6J30_RS07485	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A6J30_RS07495	COG0088	Forms part of the polypeptide exit tunnel
A6J30_RS07500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A6J30_RS07510	COG0254	rRNA binding
A6J30_RS07515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A6J30_RS07520	COG1609	Transcriptional regulator
A6J30_RS07530	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
A6J30_RS07535	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A6J30_RS07540	COG1575	Belongs to the MenA family. Type 1 subfamily
A6J30_RS07545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A6J30_RS07550	COG3074	FtsZ-dependent cytokinesis
A6J30_RS07555	COG1494	fructose-1,6-bisphosphatase
A6J30_RS07580	COG0149	triose-phosphate isomerase activity
A6J30_RS07605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A6J30_RS07620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A6J30_RS07700	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A6J30_RS07705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6J30_RS07710	COG1560	Kdo2-lipid A biosynthetic process
A6J30_RS07720	COG1519	Transferase
A6J30_RS07740	COG1028	Short-chain dehydrogenase reductase Sdr
A6J30_RS07750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A6J30_RS07765	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A6J30_RS07775	COG2089	acid synthase
A6J30_RS07780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A6J30_RS07785	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A6J30_RS07795	COG3642	lipopolysaccharide core region biosynthetic process
A6J30_RS07800	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A6J30_RS07805	COG0859	PFAM glycosyl transferase family 9
A6J30_RS07810	COG0463	Glycosyl transferase, family 2
A6J30_RS07825	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A6J30_RS07830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A6J30_RS07840	COG2194	sulfuric ester hydrolase activity
A6J30_RS07850	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A6J30_RS07855	COG2003	Belongs to the UPF0758 family
A6J30_RS07870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A6J30_RS07875	COG1309	transcriptional regulator
A6J30_RS07880	COG1560	Kdo2-lipid A biosynthetic process
A6J30_RS07885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A6J30_RS07890	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A6J30_RS07895	COG1561	YicC-like family, N-terminal region
A6J30_RS07905	COG4608	Belongs to the ABC transporter superfamily
A6J30_RS07910	COG0444	Belongs to the ABC transporter superfamily
A6J30_RS07915	COG0747	negative chemotaxis
A6J30_RS07925	COG4174	ABC transporter (Permease)
A6J30_RS07950	COG0811	peptide transport
A6J30_RS07955	COG0848	biopolymer transport protein
A6J30_RS07970	COG0194	GDP metabolic process
A6J30_RS07975	COG1758	RNA polymerase activity
A6J30_RS07980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A6J30_RS07985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A6J30_RS07990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A6J30_RS08000	COG2233	PERMEase
A6J30_RS08020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A6J30_RS08030	COG2183	response to ionizing radiation
A6J30_RS08040	COG0596	Alpha beta hydrolase
A6J30_RS08045	COG1040	competence protein
A6J30_RS08050	COG0316	Belongs to the HesB IscA family
A6J30_RS08050	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A6J30_RS08055	COG0494	nUDIX hydrolase
A6J30_RS08060	COG1218	3'(2'),5'-bisphosphate nucleotidase
A6J30_RS08070	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
A6J30_RS08075	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
A6J30_RS08080	COG3156	type II secretion system protein K
A6J30_RS08085	COG4795	General secretion pathway protein
A6J30_RS08090	COG2165	general secretion pathway protein
A6J30_RS08095	COG2165	general secretion pathway protein
A6J30_RS08100	COG2165	general secretion pathway protein
A6J30_RS08105	COG1459	type II secretion system
A6J30_RS08110	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A6J30_RS08120	COG3031	protein transport across the cell outer membrane
A6J30_RS08125	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A6J30_RS08130	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
A6J30_RS08135	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
A6J30_RS08145	COG0456	acetyltransferase
A6J30_RS08150	COG1490	D-aminoacyl-tRNA deacylase activity
A6J30_RS08155	COG1295	ribonuclease BN
A6J30_RS08170	COG1217	gtp-binding protein TYPA
A6J30_RS08180	COG0174	glutamine synthetase
A6J30_RS08190	COG3852	Histidine kinase
A6J30_RS08195	COG2204	response regulator
A6J30_RS08205	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A6J30_RS08220	COG3078	GTPase activator activity
A6J30_RS08240	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A6J30_RS08250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A6J30_RS08250	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A6J30_RS08275	COG0084	hydrolase, TatD family'
A6J30_RS08285	COG0805	protein transport
A6J30_RS08290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A6J30_RS08295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A6J30_RS08300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A6J30_RS08305	COG3165	ubiquinone biosynthetic process from chorismate
A6J30_RS08310	COG2226	methyltransferase
A6J30_RS08315	COG1322	Protein conserved in bacteria
A6J30_RS08330	COG0628	permease
A6J30_RS08360	COG1597	lipid kinase activity
A6J30_RS08390	COG2081	HI0933 family
A6J30_RS08400	COG1528	Iron-storage protein
A6J30_RS08405	COG0589	response to stress
A6J30_RS08420	COG0742	ribosomal rna small subunit methyltransferase
A6J30_RS08425	COG5002	protein histidine kinase activity
A6J30_RS08425	COG5001	Diguanylate cyclase
A6J30_RS08430	COG1522	sequence-specific DNA binding
A6J30_RS08435	COG0339	signal peptide processing
A6J30_RS08440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A6J30_RS08445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A6J30_RS08450	COG0583	DNA-binding transcription factor activity
A6J30_RS08455	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A6J30_RS08460	COG0800	Aldolase
A6J30_RS08465	COG2610	gluconate transmembrane transporter activity
A6J30_RS08470	COG3265	gluconokinase activity
A6J30_RS08475	COG0129	dihydroxy-acid dehydratase activity
A6J30_RS08490	COG0583	DNA-binding transcription factor activity
A6J30_RS08495	COG1609	Transcriptional regulator
A6J30_RS08530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6J30_RS08535	COG0601	transmembrane transport
A6J30_RS08540	COG0747	negative chemotaxis
A6J30_RS08545	COG4172	Belongs to the ABC transporter superfamily
A6J30_RS08610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6J30_RS08615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A6J30_RS08625	COG2960	long-chain fatty acid transporting porin activity
A6J30_RS08630	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A6J30_RS08635	COG0583	DNA-binding transcription factor activity
A6J30_RS08690	COG1739	Uncharacterized protein family UPF0029
A6J30_RS08695	COG1250	3-hydroxyacyl-CoA dehydrogenase
A6J30_RS08695	COG1024	Enoyl-CoA hydratase
A6J30_RS08700	COG0183	Belongs to the thiolase family
A6J30_RS08705	COG0604	alcohol dehydrogenase
A6J30_RS08720	COG0425	Belongs to the sulfur carrier protein TusA family
A6J30_RS08730	COG2119	membrane
A6J30_RS08735	COG0752	glycyl-tRNA synthetase alpha subunit
A6J30_RS08740	COG0751	glycine-tRNA ligase activity
A6J30_RS08745	COG0366	Alpha amylase catalytic
A6J30_RS08750	COG3977	Valine--pyruvate aminotransferase
A6J30_RS08755	COG0071	Belongs to the small heat shock protein (HSP20) family
A6J30_RS08770	COG0187	DNA topoisomerase II activity
A6J30_RS08775	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A6J30_RS08780	COG0592	DNA-directed DNA polymerase activity
A6J30_RS08785	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A6J30_RS08805	COG1126	abc transporter atp-binding protein
A6J30_RS08815	COG0594	ribonuclease P activity
A6J30_RS08825	COG0706	membrane insertase activity
A6J30_RS08830	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A6J30_RS08835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A6J30_RS08840	COG0445	tRNA wobble uridine modification
A6J30_RS08845	COG0357	Ribosomal RNA small subunit methyltransferase G
A6J30_RS08850	COG1192	Involved in chromosome partitioning
A6J30_RS08855	COG1475	DNA binding
A6J30_RS08860	COG3312	ion transport
A6J30_RS08865	COG0356	it plays a direct role in the translocation of protons across the membrane
A6J30_RS08880	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A6J30_RS08885	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A6J30_RS08890	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A6J30_RS08895	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A6J30_RS08900	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A6J30_RS08905	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A6J30_RS08910	COG0765	amino acid transport
A6J30_RS08915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J30_RS08920	COG2814	Major facilitator Superfamily
A6J30_RS08925	COG0583	DNA-binding transcription factor activity
A6J30_RS08935	COG0129	dihydroxy-acid dehydratase activity
A6J30_RS08940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A6J30_RS08945	COG3978	acetolactate synthase activity
A6J30_RS08955	COG0606	chelatase, subunit chli
A6J30_RS08965	COG0204	Acyl-transferase
A6J30_RS08970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A6J30_RS08975	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A6J30_RS08985	COG3084	Protein conserved in bacteria
A6J30_RS08995	COG4326	sporulation control protein
A6J30_RS09000	COG1272	protein, Hemolysin III
A6J30_RS09010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A6J30_RS09015	COG0569	domain protein
A6J30_RS09020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A6J30_RS09020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A6J30_RS09025	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A6J30_RS09030	COG0242	peptide deformylase activity
A6J30_RS09040	COG0758	DNA mediated transformation
A6J30_RS09045	COG2922	Belongs to the Smg family
A6J30_RS09050	COG0551	DNA topoisomerase type I activity
A6J30_RS09055	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A6J30_RS09060	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A6J30_RS09065	COG0009	L-threonylcarbamoyladenylate synthase
A6J30_RS09070	COG0408	coproporphyrinogen oxidase activity
A6J30_RS09075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A6J30_RS09085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A6J30_RS09150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A6J30_RS09155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A6J30_RS09160	COG0352	thiamine-phosphate diphosphorylase activity
A6J30_RS09165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A6J30_RS09170	COG2104	thiamine diphosphate biosynthetic process
A6J30_RS09175	COG2022	thiamine diphosphate biosynthetic process
A6J30_RS09185	COG0006	proline dipeptidase activity
A6J30_RS09185	COG0006	proline dipeptidase activity
A6J30_RS09215	COG3220	belongs to the UPF0276 family
A6J30_RS09225	COG0210	DNA helicase
A6J30_RS09235	COG0405	Gamma-glutamyltransferase
A6J30_RS09240	COG1280	lysine exporter protein (LysE YggA)
A6J30_RS09250	COG2962	Rard protein
A6J30_RS09255	COG0514	ATP-dependent DNA helicase (RecQ)
A6J30_RS09265	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A6J30_RS09270	COG0248	Ppx GppA phosphatase
A6J30_RS09280	COG3118	belongs to the thioredoxin family
A6J30_RS09295	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A6J30_RS09300	COG0633	Ferredoxin
A6J30_RS09355	COG3071	HemY protein
A6J30_RS09360	COG2959	enzyme of heme biosynthesis
A6J30_RS09370	COG0181	hydroxymethylbilane synthase activity
A6J30_RS09375	COG3072	Adenylate cyclase
A6J30_RS09380	COG1965	Belongs to the frataxin family
A6J30_RS09390	COG0019	diaminopimelate decarboxylase activity
A6J30_RS09395	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A6J30_RS09405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
A6J30_RS09410	COG1011	Hydrolase
A6J30_RS09415	COG2200	EAL domain
A6J30_RS09415	COG3287	FIST C domain
A6J30_RS09415	COG2199	diguanylate cyclase activity
A6J30_RS09420	COG3148	PFAM DTW domain containing protein
A6J30_RS09435	COG0561	phosphatase activity
A6J30_RS09440	COG2267	carboxylic ester hydrolase activity
A6J30_RS09445	COG1280	lysine exporter protein (LysE YggA)
A6J30_RS09450	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
A6J30_RS09455	COG0640	Transcriptional regulator
A6J30_RS09460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A6J30_RS09515	COG2095	MarC family integral membrane protein
A6J30_RS09525	COG0742	ribosomal rna small subunit methyltransferase
A6J30_RS09530	COG0552	protein localization to endoplasmic reticulum
A6J30_RS09535	COG2884	Cell division ATP-binding protein ftsE
A6J30_RS09540	COG2177	Part of the ABC transporter FtsEX involved in
A6J30_RS09555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A6J30_RS09560	COG0705	Rhomboid family
A6J30_RS09565	COG1580	Controls the rotational direction of flagella during chemotaxis
A6J30_RS09570	COG3161	chorismate lyase activity
A6J30_RS09575	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A6J30_RS09580	COG2937	Belongs to the GPAT DAPAT family
A6J30_RS09585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A6J30_RS09590	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A6J30_RS09595	COG0534	Mate efflux family protein
A6J30_RS09600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A6J30_RS09615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A6J30_RS09620	COG4206	TonB-dependent receptor
A6J30_RS09630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A6J30_RS09690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A6J30_RS09700	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A6J30_RS09735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A6J30_RS09745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A6J30_RS09750	COG0250	Participates in transcription elongation, termination and antitermination
A6J30_RS09755	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A6J30_RS09760	COG0081	regulation of translation
A6J30_RS09765	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A6J30_RS09770	COG0222	ribosome binding
A6J30_RS09775	COG0085	RNA polymerase activity
A6J30_RS09780	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A6J30_RS09785	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
A6J30_RS09790	COG2816	NAD+ diphosphatase activity
A6J30_RS09805	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A6J30_RS09810	COG1573	uracil-dna glycosylase
A6J30_RS09815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A6J30_RS09825	COG1253	flavin adenine dinucleotide binding
A6J30_RS09890	COG0151	Belongs to the GarS family
A6J30_RS09895	COG0138	bifunctional purine biosynthesis protein purh
A6J30_RS09905	COG0789	Transcriptional regulator
A6J30_RS09920	COG0531	amino acid
A6J30_RS09925	COG1982	Orn Lys Arg decarboxylase major
A6J30_RS10005	COG3706	GGDEF domain
A6J30_RS10010	COG0488	(ABC) transporter
A6J30_RS10015	COG2814	Major facilitator Superfamily
A6J30_RS10020	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
A6J30_RS10025	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A6J30_RS10030	COG2264	protein methyltransferase activity
A6J30_RS10035	COG0439	Biotin carboxylase
A6J30_RS10040	COG0511	ligase activity, forming carbon-carbon bonds
A6J30_RS10045	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A6J30_RS10050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A6J30_RS10065	COG2814	Major facilitator Superfamily
A6J30_RS10070	COG2205	protein histidine kinase activity
A6J30_RS10070	COG0784	Response regulator, receiver
A6J30_RS10090	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A6J30_RS10100	COG3263	regulation of cellular component size
A6J30_RS10110	COG4232	protein-disulfide reductase activity
A6J30_RS10115	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A6J30_RS10120	COG1027	Aspartate ammonia-lyase
A6J30_RS10125	COG3030	protein affecting phage T7 exclusion by the F plasmid
A6J30_RS10130	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A6J30_RS10140	COG2205	protein histidine kinase activity
A6J30_RS10145	COG0745	RESPONSE REGULATOR receiver
A6J30_RS10150	COG3678	ATP-independent chaperone mediated protein folding
A6J30_RS10160	COG0205	6-phosphofructokinase activity
A6J30_RS10165	COG0534	Mate efflux family protein
A6J30_RS10180	COG0459	protein refolding
A6J30_RS10200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A6J30_RS10205	COG1509	lysine 2,3-aminomutase activity
A6J30_RS10210	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A6J30_RS10220	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
A6J30_RS10225	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
A6J30_RS10230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A6J30_RS10235	COG1053	succinate dehydrogenase
A6J30_RS10245	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
A6J30_RS10265	COG4942	peptidase
A6J30_RS10270	COG1045	serine acetyltransferase
A6J30_RS10275	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A6J30_RS10280	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
A6J30_RS10285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A6J30_RS10290	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A6J30_RS10305	COG0471	metal ion transport
A6J30_RS10310	COG0688	phosphatidylethanolamine metabolic process
A6J30_RS10315	COG1162	GTPase activity
A6J30_RS10320	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A6J30_RS10395	COG0802	atpase or kinase
A6J30_RS10400	COG0860	N-Acetylmuramoyl-L-alanine amidase
A6J30_RS10405	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A6J30_RS10410	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A6J30_RS10420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A6J30_RS10425	COG0330	HflC and HflK could
A6J30_RS10430	COG0330	HflC and HflK could
A6J30_RS10435	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
A6J30_RS10440	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A6J30_RS10445	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
A6J30_RS10450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A6J30_RS10450	COG1017	nitric oxide dioxygenase activity
A6J30_RS10455	COG1959	2 iron, 2 sulfur cluster binding
A6J30_RS10460	COG0557	exoribonuclease II activity
A6J30_RS10465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A6J30_RS10470	COG0546	phosphoglycolate phosphatase activity
A6J30_RS10475	COG0180	Tryptophanyl-tRNA synthetase
A6J30_RS10490	COG0512	Glutamine amidotransferase of anthranilate synthase
A6J30_RS10495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A6J30_RS10505	COG1012	belongs to the aldehyde dehydrogenase family
A6J30_RS10515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A6J30_RS10520	COG3954	Phosphoribulokinase
A6J30_RS10525	COG3089	Belongs to the UPF0270 family
A6J30_RS10530	COG0429	hydrolase of the alpha beta-hydrolase fold
A6J30_RS10540	COG0488	(ABC) transporter
A6J30_RS10545	COG2249	NAD(P)H dehydrogenase (quinone) activity
A6J30_RS10560	COG1047	Peptidyl-prolyl cis-trans
A6J30_RS10570	COG1446	asparaginase
A6J30_RS10575	COG2900	Belongs to the SlyX family
A6J30_RS10585	COG0545	Peptidyl-prolyl cis-trans isomerase
A6J30_RS10590	COG2964	Protein conserved in bacteria
A6J30_RS10595	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A6J30_RS10600	COG2923	Belongs to the DsrF TusC family
A6J30_RS10605	COG2168	tRNA wobble position uridine thiolation
A6J30_RS10615	COG0049	tRNA binding
A6J30_RS10620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A6J30_RS10625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A6J30_RS10630	COG2906	2 iron, 2 sulfur cluster binding
A6J30_RS10640	COG0281	malic enzyme
A6J30_RS10650	COG0626	cystathionine gamma-synthase activity
A6J30_RS10655	COG0527	aspartate kinase activity
A6J30_RS10655	COG0460	homoserine dehydrogenase
A6J30_RS10660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A6J30_RS10670	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
A6J30_RS10675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A6J30_RS10680	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A6J30_RS10685	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A6J30_RS10690	COG0137	argininosuccinate synthase activity
A6J30_RS10695	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A6J30_RS10695	COG0165	Argininosuccinate lyase
A6J30_RS10710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A6J30_RS10710	COG0678	peroxiredoxin activity
A6J30_RS10720	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A6J30_RS10750	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A6J30_RS10755	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A6J30_RS10765	COG0338	D12 class N6 adenine-specific DNA methyltransferase
A6J30_RS10770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A6J30_RS10775	COG0360	Binds together with S18 to 16S ribosomal RNA
A6J30_RS10780	COG2965	DNA replication, synthesis of RNA primer
A6J30_RS10790	COG0359	binds to the 23S rRNA
A6J30_RS10805	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A6J30_RS10815	COG0432	Pfam Uncharacterised protein family UPF0047
A6J30_RS10820	COG0166	Belongs to the GPI family
A6J30_RS10830	COG0735	belongs to the Fur family
A6J30_RS10835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A6J30_RS10855	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A6J30_RS10860	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A6J30_RS10865	COG0175	sulfate reduction
A6J30_RS10940	COG0646	methionine synthase
A6J30_RS10940	COG1410	methionine synthase
A6J30_RS10945	COG0527	aspartate kinase activity
A6J30_RS10955	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A6J30_RS10965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A6J30_RS10980	COG0629	single-stranded DNA binding
A6J30_RS10985	COG2200	EAL domain
A6J30_RS10985	COG2199	diguanylate cyclase activity
A6J30_RS11010	COG3409	Peptidoglycan-binding domain 1 protein
A6J30_RS11010	COG3267	Type II secretory pathway component ExeA
A6J30_RS11020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A6J30_RS11025	COG1459	type II secretion system
A6J30_RS11035	COG2165	general secretion pathway protein
A6J30_RS11070	COG1077	Cell shape determining protein MreB Mrl
A6J30_RS11075	COG1792	Involved in formation and maintenance of cell shape
A6J30_RS11080	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A6J30_RS11085	COG0424	maF-like protein
A6J30_RS11095	COG3164	Protein of unknown function
A6J30_RS11100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A6J30_RS11105	COG0312	modulator of DNA gyrase
A6J30_RS11110	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A6J30_RS11115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A6J30_RS11130	COG0564	pseudouridine synthase activity
A6J30_RS11135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A6J30_RS11140	COG3028	Belongs to the UPF0307 family
A6J30_RS11145	COG0312	modulator of DNA gyrase
A6J30_RS11150	COG2239	Acts as a magnesium transporter
A6J30_RS11155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6J30_RS11160	COG1660	Displays ATPase and GTPase activities
A6J30_RS11165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6J30_RS11170	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A6J30_RS11180	COG1137	ATPase activity
A6J30_RS11185	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A6J30_RS11195	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A6J30_RS11195	COG0517	IMP dehydrogenase activity
A6J30_RS11205	COG1127	ABC transporter
A6J30_RS11210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A6J30_RS11215	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A6J30_RS11220	COG2854	intermembrane phospholipid transfer
A6J30_RS11230	COG5007	Belongs to the BolA IbaG family
A6J30_RS11235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A6J30_RS11240	COG0204	Acyl-transferase
A6J30_RS11245	COG0251	oxidation-reduction process
A6J30_RS11250	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
A6J30_RS11255	COG0540	Belongs to the ATCase OTCase family
A6J30_RS11265	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A6J30_RS11270	COG2235	arginine
A6J30_RS11300	COG0525	valine-tRNA ligase activity
A6J30_RS11305	COG2927	DNA polymerase III (CHI subunit)
A6J30_RS11310	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A6J30_RS11315	COG0795	lipopolysaccharide-transporting ATPase activity
A6J30_RS11335	COG1028	Short-chain dehydrogenase reductase Sdr
A6J30_RS11350	COG0726	polysaccharide deacetylase
A6J30_RS11355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A6J30_RS11360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A6J30_RS11365	COG1447	Phosphotransferase system cellobiose-specific component IIA
A6J30_RS11370	COG1486	melibiose metabolic process
A6J30_RS11375	COG3394	polysaccharide catabolic process
A6J30_RS11385	COG3437	response regulator, receiver
A6J30_RS11435	COG1012	belongs to the aldehyde dehydrogenase family
A6J30_RS11505	COG0741	lytic transglycosylase activity
A6J30_RS11510	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
A6J30_RS11520	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A6J30_RS11530	COG2066	Belongs to the glutaminase family
A6J30_RS11535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A6J30_RS11540	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A6J30_RS11550	COG1872	DUF167
A6J30_RS11555	COG0762	integral membrane protein
A6J30_RS11560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A6J30_RS11565	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A6J30_RS11580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A6J30_RS11585	COG1678	Uncharacterized ACR, COG1678
A6J30_RS11590	COG0189	ligase activity
A6J30_RS11595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A6J30_RS11600	COG2356	endonuclease I
A6J30_RS11605	COG3091	SprT-like family
A6J30_RS11615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A6J30_RS11625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A6J30_RS11630	COG0583	DNA-binding transcription factor activity
A6J30_RS11640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A6J30_RS11645	COG0126	phosphoglycerate kinase activity
A6J30_RS11650	COG0191	fructose-bisphosphate aldolase activity
A6J30_RS11655	COG0668	transmembrane transport
A6J30_RS11660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A6J30_RS11670	COG0583	DNA-binding transcription factor activity
A6J30_RS11680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A6J30_RS11685	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A6J30_RS11690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A6J30_RS11700	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
A6J30_RS11705	COG3079	Belongs to the UPF0149 family
A6J30_RS11710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A6J30_RS11715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A6J30_RS11730	COG0354	folic acid binding
A6J30_RS11735	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
A6J30_RS11745	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A6J30_RS11750	COG1595	DNA-templated transcription, initiation
A6J30_RS11755	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
A6J30_RS11765	COG3086	response to oxidative stress
A6J30_RS11770	COG0481	GTPase activity
A6J30_RS11780	COG0571	ribonuclease III activity
A6J30_RS11785	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A6J30_RS11790	COG1381	Involved in DNA repair and RecF pathway recombination
A6J30_RS11795	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A6J30_RS11800	COG0736	holo-[acyl-carrier-protein] synthase activity
A6J30_RS11815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A6J30_RS11820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A6J30_RS11825	COG3956	TIGRFAM MazG family protein
A6J30_RS11830	COG0504	CTP synthase activity
A6J30_RS11835	COG0148	phosphopyruvate hydratase activity
A6J30_RS11840	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
A6J30_RS11845	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A6J30_RS11850	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A6J30_RS11855	COG0585	pseudouridine synthase activity
A6J30_RS11860	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A6J30_RS11865	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A6J30_RS11875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A6J30_RS11880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A6J30_RS11885	COG1546	Belongs to the CinA family
A6J30_RS11890	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A6J30_RS11895	COG2137	regulation of response to DNA damage stimulus
A6J30_RS11900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A6J30_RS11905	COG0527	aspartate kinase activity
A6J30_RS11965	COG3630	sodium ion export across plasma membrane
A6J30_RS11970	COG5016	pyruvate
A6J30_RS11970	COG0511	ligase activity, forming carbon-carbon bonds
A6J30_RS11975	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A6J30_RS11985	COG1238	metal cluster binding
A6J30_RS11990	COG0612	Peptidase, M16
A6J30_RS11995	COG2918	glutathione biosynthetic process
A6J30_RS12005	COG1854	S-ribosylhomocysteine lyase activity
A6J30_RS12010	COG4536	flavin adenine dinucleotide binding
A6J30_RS12015	COG4137	Cytochrome C assembly protein
A6J30_RS12020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A6J30_RS12025	COG0228	four-way junction DNA binding
A6J30_RS12030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A6J30_RS12035	COG0336	Belongs to the RNA methyltransferase TrmD family
A6J30_RS12040	COG0335	large ribosomal subunit rRNA binding
A6J30_RS12045	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
A6J30_RS12050	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
A6J30_RS12055	COG0237	dephospho-CoA kinase activity
A6J30_RS12065	COG1459	type II secretion system
A6J30_RS12070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A6J30_RS12080	COG0157	Belongs to the NadC ModD family
A6J30_RS12090	COG2186	Transcriptional regulator
A6J30_RS12095	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A6J30_RS12100	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6J30_RS12105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A6J30_RS12120	COG0288	reversible hydration of carbon dioxide
A6J30_RS12125	COG0659	secondary active sulfate transmembrane transporter activity
A6J30_RS12130	COG1131	(ABC) transporter
A6J30_RS12135	COG0842	Transport permease protein
A6J30_RS12145	COG1560	Kdo2-lipid A biosynthetic process
A6J30_RS12150	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A6J30_RS12155	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A6J30_RS12160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A6J30_RS12170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A6J30_RS12180	COG1489	DNA binding
A6J30_RS12185	COG1643	Atp-dependent helicase
A6J30_RS12190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A6J30_RS12195	COG1752	Esterase of the alpha-beta hydrolase superfamily
A6J30_RS12200	COG1049	propionate catabolic process, 2-methylcitrate cycle
A6J30_RS12205	COG3112	Uncharacterised protein family (UPF0231)
A6J30_RS12215	COG0004	ammonium transporteR
A6J30_RS12220	COG1840	ABC-type Fe3 transport system, periplasmic component
A6J30_RS12230	COG3842	ATPase activity
A6J30_RS12235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A6J30_RS12250	COG2971	BadF BadG BcrA BcrD
A6J30_RS12260	COG4608	Belongs to the ABC transporter superfamily
A6J30_RS12265	COG0444	Belongs to the ABC transporter superfamily
A6J30_RS12270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6J30_RS12280	COG0747	negative chemotaxis
A6J30_RS12285	COG2205	protein histidine kinase activity
A6J30_RS12285	COG2198	Histidine kinase
A6J30_RS12285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J30_RS12285	COG0784	Response regulator, receiver
A6J30_RS12295	COG2813	Specifically methylates the guanine in position
A6J30_RS12300	COG0628	permease
A6J30_RS12305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A6J30_RS12310	COG0316	Belongs to the HesB IscA family
A6J30_RS12325	COG0739	heme binding
A6J30_RS12330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A6J30_RS12340	COG2027	D-alanyl-D-alanine carboxypeptidase
A6J30_RS12345	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A6J30_RS12350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A6J30_RS12355	COG1534	Rna-binding protein
A6J30_RS12365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A6J30_RS12370	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A6J30_RS12375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A6J30_RS12385	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A6J30_RS12400	COG0779	Required for maturation of 30S ribosomal subunits
A6J30_RS12405	COG0195	Participates in both transcription termination and antitermination
A6J30_RS12410	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A6J30_RS12415	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A6J30_RS12420	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A6J30_RS12425	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A6J30_RS12430	COG1185	polyribonucleotide nucleotidyltransferase activity
A6J30_RS12445	COG0534	Mate efflux family protein
A6J30_RS12450	COG0826	peptidase U32
A6J30_RS12455	COG0826	peptidase U32
A6J30_RS12465	COG3154	lipid carrier protein
A6J30_RS12470	COG3153	acetyltransferase
A6J30_RS12490	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A6J30_RS12500	COG0084	hydrolase, TatD family'
A6J30_RS12505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A6J30_RS12510	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A6J30_RS12515	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A6J30_RS12520	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A6J30_RS12525	COG0813	purine-nucleoside phosphorylase activity
A6J30_RS12535	COG0560	Phosphoserine phosphatase
A6J30_RS12545	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A6J30_RS12550	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A6J30_RS12555	COG0583	DNA-binding transcription factor activity
A6J30_RS12565	COG1022	Amp-dependent synthetase and ligase
A6J30_RS12570	COG2169	Transcriptional regulator
A6J30_RS12595	COG4964	Belongs to the GSP D family
A6J30_RS12655	COG0583	DNA-binding transcription factor activity
A6J30_RS12660	COG0531	amino acid
A6J30_RS12665	COG2731	YhcH YjgK YiaL family protein
A6J30_RS12670	COG3250	beta-galactosidase activity
A6J30_RS12675	COG1609	Transcriptional regulator
A6J30_RS12680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A6J30_RS12690	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
A6J30_RS12695	COG2017	converts alpha-aldose to the beta-anomer
A6J30_RS12700	COG1609	Transcriptional regulator
A6J30_RS12710	COG2211	Major facilitator Superfamily
A6J30_RS12715	COG1609	Transcriptional regulator
A6J30_RS12720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J30_RS12735	COG0598	Magnesium transport protein CorA
A6J30_RS12740	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A6J30_RS12745	COG1349	DNA-binding transcription factor activity
A6J30_RS12750	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A6J30_RS12755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A6J30_RS12765	COG2271	Major facilitator Superfamily
A6J30_RS12770	COG0584	glycerophosphoryl diester phosphodiesterase
A6J30_RS12775	COG2171	N-acyltransferase activity
A6J30_RS12780	COG3141	response to X-ray
A6J30_RS12800	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A6J30_RS12810	COG1074	ATP-dependent DNA helicase activity
A6J30_RS12815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A6J30_RS12825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A6J30_RS12825	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
A6J30_RS12840	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
A6J30_RS12845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A6J30_RS12850	COG2166	iron-sulfur cluster assembly
A6J30_RS12855	COG3706	GGDEF domain
A6J30_RS12860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A6J30_RS12865	COG0693	protein deglycase activity
A6J30_RS12870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A6J30_RS12875	COG3248	Nucleoside-binding outer membrane protein
A6J30_RS12900	COG1595	DNA-templated transcription, initiation
A6J30_RS12920	COG3056	Lipoprotein
A6J30_RS12925	COG2813	Specifically methylates the guanine in position
A6J30_RS12930	COG0271	Belongs to the BolA IbaG family
A6J30_RS12940	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
A6J30_RS12945	COG1805	sodium ion transport
A6J30_RS12950	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
A6J30_RS12955	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
A6J30_RS12960	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
A6J30_RS12965	COG2871	sodium ion transport
A6J30_RS12970	COG1477	protein flavinylation
A6J30_RS12985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A6J30_RS12990	COG0514	ATP-dependent DNA helicase (RecQ)
A6J30_RS12995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A6J30_RS13010	COG0733	neurotransmitter:sodium symporter activity
A6J30_RS13030	COG0442	prolyl-tRNA aminoacylation
A6J30_RS13035	COG1720	tRNA m6t6A37 methyltransferase activity
A6J30_RS13040	COG0254	rRNA binding
A6J30_RS13055	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A6J30_RS13060	COG1671	Belongs to the UPF0178 family
A6J30_RS13085	COG3098	single-species biofilm formation
A6J30_RS13090	COG0564	pseudouridine synthase activity
A6J30_RS13100	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
A6J30_RS13105	COG0024	Methionine aminopeptidase
A6J30_RS13110	COG0052	Belongs to the universal ribosomal protein uS2 family
A6J30_RS13115	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A6J30_RS13120	COG0528	UMP kinase activity
A6J30_RS13125	COG0233	cytoplasmic translational termination
A6J30_RS13130	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A6J30_RS13135	COG0575	Belongs to the CDS family
A6J30_RS13140	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A6J30_RS13145	COG0750	zinc metalloprotease
A6J30_RS13155	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
A6J30_RS13160	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A6J30_RS13165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A6J30_RS13170	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A6J30_RS13175	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A6J30_RS13180	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A6J30_RS13185	COG0587	DNA-directed DNA polymerase activity
A6J30_RS13190	COG0825	malonyl-CoA metabolic process
A6J30_RS13195	COG0037	tRNA processing
A6J30_RS13205	COG0347	Belongs to the P(II) protein family
A6J30_RS13210	COG3021	interspecies interaction between organisms
A6J30_RS13220	COG1388	LysM domain
A6J30_RS13220	COG0741	lytic transglycosylase activity
A6J30_RS13225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6J30_RS13230	COG2226	methyltransferase
A6J30_RS13235	COG0328	RNA-DNA hybrid ribonuclease activity
A6J30_RS13240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A6J30_RS13255	COG1960	acyl-CoA dehydrogenase activity
A6J30_RS13260	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
A6J30_RS13265	COG0121	glutamine amidotransferase
A6J30_RS13270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A6J30_RS13275	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A6J30_RS13280	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A6J30_RS13285	COG2233	PERMEase
A6J30_RS13305	COG1393	Belongs to the ArsC family
A6J30_RS13310	COG4783	chaperone-mediated protein folding
A6J30_RS13325	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A6J30_RS13330	COG2716	regulation of RNA biosynthetic process
A6J30_RS13335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A6J30_RS13340	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
A6J30_RS13355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A6J30_RS13360	COG1393	Belongs to the ArsC family
A6J30_RS13390	COG2837	iron assimilation
A6J30_RS13395	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J30_RS13405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J30_RS13410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J30_RS13415	COG1334	flagellar protein FlaG
A6J30_RS13420	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A6J30_RS13430	COG1516	flagellar protein fliS
A6J30_RS13450	COG1677	Flagellar hook-basal body complex protein FliE
A6J30_RS13460	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A6J30_RS13510	COG1987	bacterial-type flagellum assembly
A6J30_RS13515	COG1684	flagellar biosynthetic protein fliR
A6J30_RS13550	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
A6J30_RS13555	COG2198	Histidine kinase
A6J30_RS13555	COG0643	Histidine kinase
A6J30_RS13555	COG0784	Response regulator, receiver
A6J30_RS13560	COG2201	protein-glutamate methylesterase activity
A6J30_RS13565	COG1192	Involved in chromosome partitioning
A6J30_RS13575	COG0835	chemotaxis
A6J30_RS13585	COG4133	protoheme IX ABC transporter activity
A6J30_RS13590	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A6J30_RS13595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A6J30_RS13600	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A6J30_RS13605	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
A6J30_RS13610	COG1138	Cytochrome C-type biogenesis protein
A6J30_RS13615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A6J30_RS13630	COG2853	Lipoprotein
A6J30_RS13640	COG2067	long-chain fatty acid transport protein
A6J30_RS13660	COG0183	Belongs to the thiolase family
A6J30_RS13665	COG1250	3-hydroxyacyl-CoA dehydrogenase
A6J30_RS13665	COG1024	Enoyl-CoA hydratase
A6J30_RS13680	COG2062	phosphohistidine phosphatase, SixA
A6J30_RS13685	COG2840	Smr protein MutS2
A6J30_RS13690	COG2890	protein-(glutamine-N5) methyltransferase activity
A6J30_RS13700	COG2860	membrane
A6J30_RS13710	COG3101	peptidyl-lysine hydroxylation
A6J30_RS13725	COG0431	NADPH-dependent FMN reductase
A6J30_RS13730	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
A6J30_RS13730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6J30_RS13735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A6J30_RS13745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A6J30_RS13750	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A6J30_RS13760	COG0101	tRNA pseudouridine synthase activity
A6J30_RS13770	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A6J30_RS13775	COG0285	dihydrofolate synthase activity
A6J30_RS13780	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
A6J30_RS13785	COG1286	toxin biosynthetic process
A6J30_RS13790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A6J30_RS13795	COG0583	DNA-binding transcription factor activity
A6J30_RS13800	COG0745	RESPONSE REGULATOR receiver
A6J30_RS13810	COG2832	Protein of unknown function (DUF454)
A6J30_RS13815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A6J30_RS13825	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A6J30_RS13830	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A6J30_RS13835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A6J30_RS13840	COG0814	amino acid
A6J30_RS13845	COG0251	oxidation-reduction process
A6J30_RS13850	COG3681	Belongs to the UPF0597 family
A6J30_RS13865	COG2261	transglycosylase associated protein
A6J30_RS13870	COG2983	Belongs to the UPF0260 family
A6J30_RS13875	COG0668	transmembrane transport
A6J30_RS13880	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A6J30_RS13885	COG0346	lactoylglutathione lyase activity
A6J30_RS13895	COG1785	Belongs to the alkaline phosphatase family
A6J30_RS13915	COG2226	methyltransferase
A6J30_RS13930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A6J30_RS13935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6J30_RS13945	COG3139	Protein of unknown function (DUF1315)
A6J30_RS13950	COG0252	asparaginase activity
A6J30_RS13955	COG0616	signal peptide processing
A6J30_RS13960	COG0446	pyridine nucleotide-disulphide oxidoreductase
A6J30_RS13960	COG1902	pentaerythritol trinitrate reductase activity
A6J30_RS13965	COG0778	Nitroreductase
A6J30_RS13970	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A6J30_RS13990	COG0123	including yeast histone deacetylase and acetoin utilization protein
A6J30_RS14050	COG0582	viral genome integration into host DNA
A6J30_RS14060	COG3083	sulfuric ester hydrolase activity
A6J30_RS14065	COG3082	Protein of unknown function (DUF1414)
A6J30_RS14070	COG3081	Nucleoid-associated protein
A6J30_RS14085	COG1757	Na H antiporter
A6J30_RS14090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A6J30_RS14095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A6J30_RS14100	COG2095	MarC family integral membrane protein
A6J30_RS14105	COG1012	belongs to the aldehyde dehydrogenase family
A6J30_RS14105	COG1454	alcohol dehydrogenase
A6J30_RS14125	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A6J30_RS14135	COG2056	Na+-H+ antiporter family
A6J30_RS14140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A6J30_RS14145	COG2885	chlorophyll binding
A6J30_RS14155	COG0346	lactoylglutathione lyase activity
A6J30_RS14160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A6J30_RS14165	COG4660	Part of a membrane complex involved in electron transport
A6J30_RS14170	COG4659	FMN binding
A6J30_RS14175	COG4658	electron transport chain
A6J30_RS14180	COG4656	Part of a membrane complex involved in electron transport
A6J30_RS14185	COG2878	Part of a membrane complex involved in electron transport
A6J30_RS14190	COG4657	Part of a membrane complex involved in electron transport
A6J30_RS14205	COG0556	nucleotide-excision repair
A6J30_RS14210	COG2204	response regulator
A6J30_RS14215	COG2198	Histidine kinase
A6J30_RS14220	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A6J30_RS14225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A6J30_RS14230	COG0521	Mo-molybdopterin cofactor biosynthetic process
A6J30_RS14235	COG0315	cyclic pyranopterin monophosphate synthase activity
A6J30_RS14240	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A6J30_RS14245	COG0314	molybdopterin synthase activity
A6J30_RS14255	COG0601	transmembrane transport
A6J30_RS14260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6J30_RS14265	COG0444	Belongs to the ABC transporter superfamily
A6J30_RS14275	COG0435	Glutathione S-transferase
A6J30_RS14285	COG3174	membrane
A6J30_RS14290	COG0280	phosphate acetyltransferase
A6J30_RS14290	COG0857	belongs to the CobB CobQ family
A6J30_RS14295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A6J30_RS14300	COG3092	negative regulation of chromosome organization
A6J30_RS14310	COG4120	Belongs to the binding-protein-dependent transport system permease family
A6J30_RS14315	COG1122	ATPase activity
A6J30_RS14320	COG0366	Alpha amylase catalytic
A6J30_RS14330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A6J30_RS14335	COG0653	protein targeting
A6J30_RS14340	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
A6J30_RS14345	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A6J30_RS14350	COG2186	Transcriptional regulator
A6J30_RS14360	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J30_RS14360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J30_RS14365	COG0489	protein tyrosine kinase activity
A6J30_RS14370	COG0572	uridine kinase
A6J30_RS14380	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A6J30_RS14385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A6J30_RS14390	COG0659	secondary active sulfate transmembrane transporter activity
A6J30_RS14400	COG1530	ribonuclease E activity
A6J30_RS14410	COG0564	pseudouridine synthase activity
A6J30_RS14415	COG0424	maF-like protein
A6J30_RS14420	COG1399	metal-binding, possibly nucleic acid-binding protein
A6J30_RS14430	COG0416	fatty acid biosynthetic process
A6J30_RS14435	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A6J30_RS14465	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A6J30_RS14470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A6J30_RS14480	COG0084	hydrolase, TatD family'
A6J30_RS14485	COG1263	PTS System
A6J30_RS14485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J30_RS14500	COG0733	neurotransmitter:sodium symporter activity
A6J30_RS14515	COG4667	esterase of the alpha-beta hydrolase superfamily
A6J30_RS14520	COG0469	pyruvate kinase activity
A6J30_RS14525	COG1940	carbohydrate kinase activity
A6J30_RS14530	COG0835	chemotaxis
A6J30_RS14530	COG0784	Response regulator, receiver
A6J30_RS14535	COG0587	DNA-directed DNA polymerase activity
A6J30_RS14550	COG1028	Short-chain dehydrogenase reductase Sdr
A6J30_RS14555	COG0616	signal peptide processing
A6J30_RS14560	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A6J30_RS14565	COG0539	negative regulation of cytoplasmic translation
A6J30_RS14575	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
A6J30_RS14580	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
A6J30_RS14585	COG0284	orotidine-5'-phosphate decarboxylase activity
A6J30_RS14590	COG4166	transmembrane transport
A6J30_RS14615	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A6J30_RS14625	COG3008	intermembrane lipid transfer
A6J30_RS14625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A6J30_RS14630	COG2995	paraquat-inducible protein a
A6J30_RS14635	COG3258	Cytochrome c
A6J30_RS14640	COG2863	cytochrome
A6J30_RS14680	COG4232	protein-disulfide reductase activity
A6J30_RS14685	COG3118	belongs to the thioredoxin family
A6J30_RS14715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6J30_RS14725	COG0577	efflux transmembrane transporter activity
A6J30_RS14725	COG1136	(ABC) transporter
A6J30_RS14730	COG0577	efflux transmembrane transporter activity
A6J30_RS14730	COG1136	(ABC) transporter
A6J30_RS14735	COG0577	efflux transmembrane transporter activity
A6J30_RS14735	COG1136	(ABC) transporter
A6J30_RS14740	COG1335	isochorismatase
A6J30_RS14745	COG1917	Cupin 2, conserved barrel domain protein
A6J30_RS14745	COG2207	Transcriptional regulator
A6J30_RS14790	COG5002	protein histidine kinase activity
A6J30_RS14790	COG3850	Histidine kinase
A6J30_RS14795	COG0745	RESPONSE REGULATOR receiver
A6J30_RS14800	COG0840	transmembrane signaling receptor activity
A6J30_RS14805	COG1032	radical SAM domain protein
A6J30_RS14810	COG2203	Gaf domain
A6J30_RS14810	COG3706	GGDEF domain
A6J30_RS14810	COG4251	negative regulation of phosphorylation
A6J30_RS14810	COG5001	Diguanylate cyclase
A6J30_RS14830	COG0583	DNA-binding transcription factor activity
A6J30_RS14840	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A6J30_RS14850	COG2350	Protein conserved in bacteria
A6J30_RS14860	COG2917	probably involved in intracellular septation
A6J30_RS14880	COG1301	dicarboxylic acid transport
A6J30_RS14890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A6J30_RS14895	COG0159	tryptophan synthase activity
A6J30_RS14900	COG0133	tryptophan synthase activity
A6J30_RS14905	COG0134	indole-3-glycerol-phosphate synthase activity
A6J30_RS14905	COG0135	phosphoribosylanthranilate isomerase activity
A6J30_RS14910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A6J30_RS14915	COG0512	Glutamine amidotransferase of anthranilate synthase
A6J30_RS14920	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A6J30_RS14930	COG0613	PHP domain protein
A6J30_RS14935	COG0009	L-threonylcarbamoyladenylate synthase
A6J30_RS14945	COG1187	pseudouridine synthase activity
A6J30_RS14950	COG3099	Belongs to the UPF0263 family
A6J30_RS14955	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A6J30_RS14965	COG0417	DNA replication proofreading
A6J30_RS14970	COG2197	response regulator
A6J30_RS14975	COG0322	excinuclease ABC activity
A6J30_RS15020	COG0019	diaminopimelate decarboxylase activity
A6J30_RS15045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A6J30_RS15050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A6J30_RS15060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A6J30_RS15080	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
A6J30_RS15090	COG0437	4 iron, 4 sulfur cluster binding
A6J30_RS15095	COG3301	Polysulphide reductase, NrfD
A6J30_RS15110	COG3088	subunit of a heme lyase
A6J30_RS15110	COG4235	cytochrome complex assembly
A6J30_RS15120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A6J30_RS15145	COG2989	Protein conserved in bacteria
A6J30_RS15150	COG3108	Peptidase M15
A6J30_RS15155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6J30_RS15170	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
A6J30_RS15195	COG1846	Transcriptional regulator
A6J30_RS15200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A6J30_RS15205	COG0840	transmembrane signaling receptor activity
A6J30_RS15225	COG1448	Aminotransferase
A6J30_RS15240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J30_RS15250	COG0017	Asparaginyl-tRNA synthetase
A6J30_RS15255	COG0840	transmembrane signaling receptor activity
A6J30_RS15275	COG1278	Cold shock
A6J30_RS15305	COG0720	synthase
A6J30_RS15315	COG2200	EAL domain
A6J30_RS15320	COG1760	l-serine dehydratase
A6J30_RS15325	COG0814	amino acid
A6J30_RS15330	COG0494	nUDIX hydrolase
A6J30_RS15340	COG2205	protein histidine kinase activity
A6J30_RS15340	COG0784	Response regulator, receiver
A6J30_RS15345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A6J30_RS15360	COG3106	COG3106 Predicted ATPase
A6J30_RS15365	COG3768	UPF0283 membrane protein
A6J30_RS15375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J30_RS15395	COG0346	lactoylglutathione lyase activity
A6J30_RS15650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A6J30_RS15685	COG2161	toxin-antitoxin pair type II binding
A6J30_RS15690	COG4115	mRNA cleavage
A6J30_RS15750	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A6J30_RS15790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6J30_RS15865	COG0251	oxidation-reduction process
A6J30_RS15945	COG1757	Na H antiporter
A6J30_RS15950	COG0174	glutamine synthetase
A6J30_RS15960	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A6J30_RS15965	COG1396	sequence-specific DNA binding
A6J30_RS15965	COG1917	Cupin 2, conserved barrel domain protein
A6J30_RS15970	COG1012	belongs to the aldehyde dehydrogenase family
A6J30_RS15975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6J30_RS15985	COG2957	Belongs to the agmatine deiminase family
A6J30_RS15990	COG1012	belongs to the aldehyde dehydrogenase family
A6J30_RS15995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A6J30_RS16000	COG1227	inorganic diphosphatase activity
A6J30_RS16005	COG2200	EAL domain
A6J30_RS16005	COG2771	luxR family
A6J30_RS16020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A6J30_RS16035	COG1846	Transcriptional regulator
A6J30_RS16040	COG2315	Protein conserved in bacteria
A6J30_RS16060	COG0110	maltose O-acetyltransferase activity
A6J30_RS16085	COG1289	transmembrane transporter activity
A6J30_RS16120	COG4771	TonB-dependent receptor
A6J30_RS16120	COG1629	transport
A6J30_RS16135	COG0789	Transcriptional regulator
A6J30_RS16140	COG4604	ABC transporter, ATP-binding protein
A6J30_RS16145	COG4605	iron ion homeostasis
A6J30_RS16150	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J30_RS16155	COG4607	ABC-type enterochelin transport system periplasmic component
A6J30_RS16175	COG2847	Copper chaperone PCu(A)C
A6J30_RS16180	COG0443	Heat shock 70 kDa protein
A6J30_RS16215	COG0625	glutathione transferase activity
A6J30_RS16230	COG4160	amino acid transport
A6J30_RS16235	COG4215	(ABC) transporter
A6J30_RS16240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J30_RS16245	COG1126	abc transporter atp-binding protein
A6J30_RS16255	COG1902	pentaerythritol trinitrate reductase activity
A6J30_RS16270	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A6J30_RS16275	COG1845	cytochrome c oxidase, subunit III
A6J30_RS16280	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A6J30_RS16285	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A6J30_RS16290	COG1028	Short-chain dehydrogenase reductase Sdr
A6J30_RS16300	COG1024	Enoyl-CoA hydratase
A6J30_RS16305	COG1024	Enoyl-CoA hydratase
A6J30_RS16320	COG0183	Belongs to the thiolase family
A6J30_RS16330	COG1960	acyl-CoA dehydrogenase activity
A6J30_RS16335	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A6J30_RS16340	COG1024	Enoyl-CoA hydratase
A6J30_RS16365	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A6J30_RS16375	COG5001	Diguanylate cyclase
A6J30_RS16380	COG0513	Belongs to the DEAD box helicase family
A6J30_RS16385	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
A6J30_RS16400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A6J30_RS16420	COG0641	radical SAM
A6J30_RS16440	COG0840	transmembrane signaling receptor activity
A6J30_RS16445	COG1119	ATPase activity
A6J30_RS16450	COG2200	EAL domain
A6J30_RS16470	COG0513	Belongs to the DEAD box helicase family
A6J30_RS16475	COG0523	cobalamin synthesis protein
A6J30_RS16485	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
A6J30_RS16495	COG0133	tryptophan synthase activity
A6J30_RS16500	COG4628	conserved protein (DUF2132)
A6J30_RS16505	COG0513	Belongs to the DEAD box helicase family
A6J30_RS16510	COG3530	Putative quorum-sensing-regulated virulence factor
A6J30_RS16530	COG2154	pterin-4-alpha-carbinolamine dehydratase
A6J30_RS16535	COG3186	Phenylalanine-4-hydroxylase
A6J30_RS16540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A6J30_RS16545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A6J30_RS16580	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
A6J30_RS16585	COG1454	alcohol dehydrogenase
A6J30_RS16590	COG2133	pyrroloquinoline quinone binding
A6J30_RS16600	COG0783	Belongs to the Dps family
A6J30_RS16605	COG0840	transmembrane signaling receptor activity
A6J30_RS16615	COG0577	efflux transmembrane transporter activity
A6J30_RS16615	COG1136	(ABC) transporter
A6J30_RS16635	COG2199	diguanylate cyclase activity
A6J30_RS16650	COG3036	rescue of stalled ribosome
A6J30_RS16655	COG1278	Cold shock
A6J30_RS16690	COG0109	protoheme IX farnesyltransferase activity
A6J30_RS16695	COG1612	heme a metabolic process
A6J30_RS16720	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
A6J30_RS16730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A6J30_RS16735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A6J30_RS16745	COG1280	lysine exporter protein (LysE YggA)
A6J30_RS16750	COG2207	Transcriptional regulator
A6J30_RS16775	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A6J30_RS16780	COG0697	spore germination
A6J30_RS16805	COG2814	Major facilitator Superfamily
A6J30_RS16810	COG0583	DNA-binding transcription factor activity
A6J30_RS16815	COG5001	Diguanylate cyclase
A6J30_RS16820	COG0739	heme binding
A6J30_RS16840	COG3314	Sporulation integral membrane protein YlbJ
A6J30_RS16855	COG0814	amino acid
A6J30_RS16875	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A6J30_RS16880	COG1072	(Pantothenic acid kinase))
A6J30_RS16890	COG1063	alcohol dehydrogenase
A6J30_RS16895	COG2213	PTS system mannitol-specific
A6J30_RS16900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6J30_RS16930	COG1881	PFAM PEBP family protein
A6J30_RS16940	COG2706	6-phosphogluconolactonase activity
A6J30_RS16960	COG1131	(ABC) transporter
A6J30_RS16965	COG0842	Transport permease protein
A6J30_RS16980	COG3383	formate dehydrogenase (NAD+) activity
A6J30_RS17035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J30_RS17045	COG2067	long-chain fatty acid transport protein
A6J30_RS17055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6J30_RS17065	COG1505	serine-type exopeptidase activity
A6J30_RS17070	COG0488	(ABC) transporter
A6J30_RS17075	COG0589	response to stress
A6J30_RS17080	COG2249	NAD(P)H dehydrogenase (quinone) activity
A6J30_RS17100	COG0366	Alpha amylase catalytic
A6J30_RS17110	COG4934	collagen metabolic process
A6J30_RS17125	COG0583	DNA-binding transcription factor activity
A6J30_RS17135	COG0783	Belongs to the Dps family
A6J30_RS17140	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
A6J30_RS17215	COG0328	RNA-DNA hybrid ribonuclease activity
A6J30_RS17245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A6J30_RS17250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A6J30_RS17260	COG0835	chemotaxis
A6J30_RS17260	COG0784	Response regulator, receiver
A6J30_RS17270	COG0748	coenzyme F420 binding
A6J30_RS17275	COG3721	Heme iron utilization protein
A6J30_RS17290	COG0811	peptide transport
A6J30_RS17295	COG0848	biopolymer transport protein
A6J30_RS17305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J30_RS17310	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A6J30_RS17355	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A6J30_RS17360	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A6J30_RS17365	COG3217	Mosc domain protein beta barrel domain protein
A6J30_RS17365	COG3217	Mosc domain protein beta barrel domain protein
A6J30_RS17365	COG0633	Ferredoxin
A6J30_RS17365	COG0633	Ferredoxin
A6J30_RS17375	COG0401	homolog of Blt101
A6J30_RS17385	COG0418	dihydroorotase activity
A6J30_RS17390	COG2354	Protein conserved in bacteria
A6J30_RS17420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A6J30_RS17420	COG2207	Transcriptional regulator
A6J30_RS17425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J30_RS17465	COG0513	Belongs to the DEAD box helicase family
A6J30_RS17475	COG0583	DNA-binding transcription factor activity
A6J30_RS17490	COG1902	pentaerythritol trinitrate reductase activity
A6J30_RS17495	COG1063	alcohol dehydrogenase
A6J30_RS17505	COG1028	Short-chain dehydrogenase reductase Sdr
A6J30_RS17520	COG3122	Protein conserved in bacteria
A6J30_RS17535	COG0583	DNA-binding transcription factor activity
A6J30_RS17540	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A6J30_RS17545	COG0252	asparaginase activity
A6J30_RS17550	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
A6J30_RS17555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A6J30_RS17555	COG0574	Belongs to the PEP-utilizing enzyme family
A6J30_RS17570	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A6J30_RS17590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6J30_RS17610	COG3706	GGDEF domain
A6J30_RS17630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A6J30_RS17660	COG3842	ATPase activity
A6J30_RS17705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A6J30_RS17750	COG0583	DNA-binding transcription factor activity
A6J30_RS17760	COG4948	Mandelate Racemase Muconate Lactonizing
A6J30_RS17795	COG1342	Belongs to the UPF0251 family
A6J30_RS17805	COG3015	lipoprotein NlpE involved in copper resistance
A6J30_RS17810	COG3713	MltA-interacting MipA family protein
A6J30_RS17825	COG0583	DNA-binding transcription factor activity
A6J30_RS17850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A6J30_RS17860	COG1335	isochorismatase
A6J30_RS17870	COG0753	catalase activity
A6J30_RS17880	COG1349	DNA-binding transcription factor activity
A6J30_RS17885	COG0346	lactoylglutathione lyase activity
A6J30_RS17900	COG0583	DNA-binding transcription factor activity
A6J30_RS17910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A6J30_RS17915	COG2070	2-Nitropropane dioxygenase
A6J30_RS17920	COG0737	Belongs to the 5'-nucleotidase family
A6J30_RS17930	COG1309	transcriptional regulator
A6J30_RS17950	COG1280	lysine exporter protein (LysE YggA)
A6J30_RS17965	COG0459	protein refolding
A6J30_RS17970	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A6J30_RS17975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A6J30_RS18005	COG1304	FMN binding
A6J30_RS18025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J30_RS18030	COG1256	bacterial-type flagellum assembly
A6J30_RS18030	COG4786	Flagellar basal body rod
A6J30_RS18040	COG1706	bacterial-type flagellum-dependent cell motility
A6J30_RS18045	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
A6J30_RS18050	COG4786	Flagellar basal body rod
A6J30_RS18055	COG4787	bacterial-type flagellum-dependent cell motility
A6J30_RS18060	COG1749	Flagellar hook protein flgE
A6J30_RS18065	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A6J30_RS18070	COG1558	bacterial-type flagellum-dependent cell motility
A6J30_RS18075	COG1815	bacterial-type flagellum-dependent cell motility
A6J30_RS18095	COG0741	lytic transglycosylase activity
A6J30_RS18100	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A6J30_RS18120	COG1760	l-serine dehydratase
A6J30_RS18125	COG3104	oligopeptide transport
A6J30_RS18145	COG0583	DNA-binding transcription factor activity
A6J30_RS18155	COG2866	Carboxypeptidase
A6J30_RS18160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6J30_RS18170	COG2990	Protein conserved in bacteria
A6J30_RS18195	COG3842	ATPase activity
A6J30_RS18205	COG1840	ABC-type Fe3 transport system, periplasmic component
A6J30_RS18210	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A6J30_RS18215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A6J30_RS18220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A6J30_RS18225	COG1609	Transcriptional regulator
A6J30_RS18255	COG3240	lipase activity
A6J30_RS18265	COG1136	(ABC) transporter
A6J30_RS18265	COG0577	efflux transmembrane transporter activity
A6J30_RS18270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6J30_RS18275	COG2067	long-chain fatty acid transport protein
A6J30_RS18285	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
A6J30_RS18300	COG1011	Hydrolase
A6J30_RS18340	COG0110	maltose O-acetyltransferase activity
A6J30_RS18345	COG1765	OsmC-like protein
A6J30_RS18350	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6J30_RS18350	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6J30_RS18365	COG3046	protein related to deoxyribodipyrimidine photolyase
A6J30_RS18370	COG0415	Belongs to the DNA photolyase family
A6J30_RS18390	COG0840	transmembrane signaling receptor activity
A6J30_RS18410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A6J30_RS18425	COG3033	Beta-eliminating lyase
A6J30_RS18435	COG0579	oxidoreductase
A6J30_RS18450	COG1114	Component of the transport system for branched-chain amino acids
A6J30_RS18455	COG3706	GGDEF domain
A6J30_RS18500	COG0583	DNA-binding transcription factor activity
A6J30_RS18510	COG0189	ligase activity
A6J30_RS18515	COG4067	protein conserved in archaea
A6J30_RS18515	COG0189	ligase activity
A6J30_RS18525	COG1166	arginine decarboxylase activity
A6J30_RS18530	COG0010	Belongs to the arginase family
A6J30_RS18535	COG2814	Major facilitator Superfamily
A6J30_RS18540	COG1770	oligopeptidase
A6J30_RS18555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A6J30_RS18560	COG1121	(ABC) transporter
A6J30_RS18565	COG0803	Belongs to the bacterial solute-binding protein 9 family
A6J30_RS18605	COG0848	biopolymer transport protein
A6J30_RS18610	COG0811	peptide transport
A6J30_RS18615	COG0811	peptide transport
A6J30_RS18635	COG0745	RESPONSE REGULATOR receiver
A6J30_RS18640	COG0039	L-malate dehydrogenase activity
A6J30_RS18645	COG0584	glycerophosphoryl diester phosphodiesterase
A6J30_RS18655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A6J30_RS18710	COG1901	pseudouridine methyltransferase
A6J30_RS18715	COG0312	modulator of DNA gyrase
A6J30_RS18720	COG0312	modulator of DNA gyrase
A6J30_RS18725	COG0351	phosphomethylpyrimidine kinase
A6J30_RS18730	COG1116	anion transmembrane transporter activity
A6J30_RS18735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6J30_RS18745	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A6J30_RS18750	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
A6J30_RS18755	COG0352	thiamine-phosphate diphosphorylase activity
A6J30_RS18765	COG0243	molybdopterin cofactor binding
A6J30_RS18770	COG3005	denitrification pathway
A6J30_RS18780	COG1028	Short-chain dehydrogenase reductase Sdr
A6J30_RS18795	COG0456	acetyltransferase
A6J30_RS18815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J30_RS18820	COG1929	Belongs to the glycerate kinase type-1 family
A6J30_RS18825	COG2610	gluconate transmembrane transporter activity
A6J30_RS18830	COG3835	regulator
A6J30_RS18855	COG0546	phosphoglycolate phosphatase activity
A6J30_RS18870	COG0583	DNA-binding transcription factor activity
A6J30_RS18880	COG0583	DNA-binding transcription factor activity
A6J30_RS18890	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
A6J30_RS18895	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
A6J30_RS18895	COG3408	Glycogen debranching enzyme
A6J30_RS18925	COG3047	cAMP biosynthetic process
A6J30_RS18930	COG1357	PFAM Pentapeptide repeats (8 copies)
A6J30_RS18960	COG2375	cellular response to nickel ion
A6J30_RS18965	COG0823	Involved in the tonB-independent uptake of proteins
A6J30_RS18970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A6J30_RS18990	COG0800	Aldolase
A6J30_RS18995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A6J30_RS19010	COG1917	Cupin 2, conserved barrel domain protein
A6J30_RS19020	COG1028	Short-chain dehydrogenase reductase Sdr
A6J30_RS19025	COG1414	Transcriptional regulator
A6J30_RS19040	COG0583	DNA-binding transcription factor activity
A6J30_RS19045	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A6J30_RS19050	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
A6J30_RS19065	COG2199	diguanylate cyclase activity
A6J30_RS19075	COG0561	phosphatase activity
A6J30_RS19080	COG0583	DNA-binding transcription factor activity
A6J30_RS19095	COG0564	pseudouridine synthase activity
A6J30_RS19100	COG0534	Mate efflux family protein
A6J30_RS19110	COG5001	Diguanylate cyclase
A6J30_RS19120	COG3123	guanosine phosphorylase activity
A6J30_RS19160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A6J30_RS19175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A6J30_RS19180	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A6J30_RS19190	COG2259	Doxx family
A6J30_RS19195	COG1741	Belongs to the pirin family
A6J30_RS19215	COG0363	glucosamine-6-phosphate deaminase activity
A6J30_RS19230	COG0786	glutamate:sodium symporter activity
A6J30_RS19235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J30_RS19240	COG1131	(ABC) transporter
A6J30_RS19250	COG0786	glutamate:sodium symporter activity
A6J30_RS19280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A6J30_RS19290	COG3279	Response regulator of the LytR AlgR family
A6J30_RS19295	COG3275	phosphorelay sensor kinase activity
A6J30_RS19315	COG1136	(ABC) transporter
A6J30_RS19330	COG0772	Belongs to the SEDS family
A6J30_RS19335	COG0217	transcriptional regulatory protein
A6J30_RS19355	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
A6J30_RS19355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A6J30_RS19365	COG0444	Belongs to the ABC transporter superfamily
A6J30_RS19370	COG4608	Belongs to the ABC transporter superfamily
A6J30_RS19400	COG1444	tRNA N-acetyltransferase activity
A6J30_RS19420	COG3340	Belongs to the peptidase S51 family
A6J30_RS19425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
A6J30_RS19430	COG1263	PTS System
A6J30_RS19430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J30_RS19435	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A6J30_RS19450	COG4166	transmembrane transport
A6J30_RS19495	COG0259	pyridoxamine-phosphate oxidase activity
A6J30_RS19525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A6J30_RS19570	COG1132	(ABC) transporter
A6J30_RS19580	COG2207	Transcriptional regulator
A6J30_RS19605	COG0800	Aldolase
A6J30_RS19610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A6J30_RS19615	COG1904	glucuronate isomerase
A6J30_RS19620	COG0246	Mannitol dehydrogenase
A6J30_RS19630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A6J30_RS19640	COG2186	Transcriptional regulator
A6J30_RS19645	COG1312	Catalyzes the dehydration of D-mannonate
A6J30_RS19650	COG0513	Belongs to the DEAD box helicase family
A6J30_RS19655	COG2258	MOSC domain
A6J30_RS19670	COG1486	melibiose metabolic process
A6J30_RS19675	COG0583	DNA-binding transcription factor activity
A6J30_RS19695	COG1595	DNA-templated transcription, initiation
A6J30_RS19725	COG3634	alkyl hydroperoxide reductase activity
A6J30_RS19735	COG1846	Transcriptional regulator
A6J30_RS19740	COG1764	response to oxidative stress
A6J30_RS19765	COG2160	L-arabinose isomerase activity
A6J30_RS19775	COG1069	ribulokinase activity
A6J30_RS19780	COG1879	ABC-type sugar transport system periplasmic component
A6J30_RS19785	COG1129	ABC transporter
A6J30_RS19790	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6J30_RS19795	COG0826	peptidase U32
A6J30_RS19815	COG0642	Histidine kinase
A6J30_RS19820	COG1653	transport
A6J30_RS19825	COG0019	diaminopimelate decarboxylase activity
A6J30_RS19830	COG4264	IucA IucC family
A6J30_RS19855	COG4772	TonB-dependent receptor
A6J30_RS19860	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A6J30_RS19865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J30_RS19870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6J30_RS19875	COG1120	ATPase activity
A6J30_RS19880	COG0840	transmembrane signaling receptor activity
A6J30_RS19885	COG0612	Peptidase, M16
A6J30_RS19895	COG0739	heme binding
A6J30_RS19920	COG4580	involved in the transport of maltose and maltodextrins
A6J30_RS19940	COG2356	endonuclease I
A6J30_RS19960	COG1982	Orn Lys Arg decarboxylase major
A6J30_RS19965	COG0531	amino acid
A6J30_RS19975	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
A6J30_RS19985	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
A6J30_RS19990	COG1162	GTPase activity
A6J30_RS19995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6J30_RS19995	COG1263	PTS System
A6J30_RS20005	COG1999	signal sequence binding
A6J30_RS20020	COG2909	trisaccharide binding
A6J30_RS20030	COG0058	SHG alpha-glucan phosphorylase activity
A6J30_RS20035	COG1640	4-alpha-glucanotransferase
A6J30_RS20040	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A6J30_RS20045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A6J30_RS20050	COG0366	Alpha amylase catalytic
A6J30_RS20065	COG3366	ferrous iron transmembrane transporter activity
A6J30_RS20070	COG0700	Nucleoside recognition
A6J30_RS20075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A6J30_RS20080	COG3339	Conserved Protein
A6J30_RS20085	COG1301	dicarboxylic acid transport
A6J30_RS20095	COG0583	DNA-binding transcription factor activity
A6J30_RS20110	COG0489	protein tyrosine kinase activity
A6J30_RS20110	COG3206	protein involved in exopolysaccharide biosynthesis
A6J30_RS20130	COG2095	MarC family integral membrane protein
A6J30_RS20135	COG4667	esterase of the alpha-beta hydrolase superfamily
A6J30_RS20140	COG3397	chitin binding
A6J30_RS20145	COG1054	Belongs to the UPF0176 family
A6J30_RS20160	COG1686	Belongs to the peptidase S11 family
A6J30_RS20185	COG0583	DNA-binding transcription factor activity
A6J30_RS20190	COG4628	conserved protein (DUF2132)
A6J30_RS20200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A6J30_RS20210	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
A6J30_RS20215	COG0628	permease
A6J30_RS20260	COG2814	Major facilitator Superfamily
A6J30_RS20275	COG0454	-acetyltransferase
A6J30_RS20285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A6J30_RS20290	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A6J30_RS20295	COG1882	Formate acetyltransferase
A6J30_RS20340	COG1360	Flagellar Motor Protein
A6J30_RS20345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A6J30_RS20350	COG1191	sigma factor activity
A6J30_RS20355	COG1580	Controls the rotational direction of flagella during chemotaxis
A6J30_RS20370	COG1516	flagellar protein fliS
A6J30_RS20375	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A6J30_RS20385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6J30_RS20400	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A6J30_RS20410	COG1987	bacterial-type flagellum assembly
A6J30_RS20490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A6J30_RS20510	COG0346	lactoylglutathione lyase activity
A6J30_RS20540	COG0745	RESPONSE REGULATOR receiver
A6J30_RS20560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J30_RS20570	COG0156	8-amino-7-oxononanoate synthase activity
A6J30_RS20575	COG1063	alcohol dehydrogenase
A6J30_RS20610	COG0668	transmembrane transport
A6J30_RS20620	COG1304	FMN binding
A6J30_RS20625	COG1620	l-lactate permease
A6J30_RS20630	COG0583	DNA-binding transcription factor activity
A6J30_RS20635	COG1505	serine-type exopeptidase activity
A6J30_RS20640	COG4172	Belongs to the ABC transporter superfamily
A6J30_RS20650	COG1067	ATP-dependent peptidase activity
A6J30_RS20675	COG1247	-acetyltransferase
A6J30_RS20680	COG0437	4 iron, 4 sulfur cluster binding
A6J30_RS20685	COG0348	domain, Protein
A6J30_RS20700	COG1122	ATPase activity
A6J30_RS20705	COG4720	Psort location CytoplasmicMembrane, score
A6J30_RS20710	COG1566	PFAM secretion protein HlyD family protein
A6J30_RS20720	COG3706	GGDEF domain
A6J30_RS20735	COG0813	purine-nucleoside phosphorylase activity
A6J30_RS20740	COG3272	Protein of unknown function (DUF1722)
A6J30_RS20745	COG0789	Transcriptional regulator
A6J30_RS20750	COG0415	Belongs to the DNA photolyase family
A6J30_RS20755	COG1388	LysM domain
A6J30_RS20755	COG1376	ErfK ybiS ycfS ynhG family protein
A6J30_RS20765	COG0513	Belongs to the DEAD box helicase family
A6J30_RS20770	COG1770	oligopeptidase
A6J30_RS20775	COG4771	TonB-dependent receptor
A6J30_RS20805	COG0573	inorganic phosphate transmembrane transporter activity
A6J30_RS20810	COG0581	inorganic phosphate transmembrane transporter activity
A6J30_RS20815	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A6J30_RS20830	COG2304	oxidoreductase activity
A6J30_RS20850	COG0714	Associated with various cellular activities
A6J30_RS20855	COG0840	transmembrane signaling receptor activity
A6J30_RS20865	COG2197	response regulator
A6J30_RS20915	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A6J30_RS20920	COG1120	ATPase activity
A6J30_RS20925	COG4774	siderophore transport
A6J30_RS20930	COG1132	(ABC) transporter
A6J30_RS20935	COG2205	protein histidine kinase activity
A6J30_RS20945	COG0569	domain protein
A6J30_RS20950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A6J30_RS20960	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
A6J30_RS20965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A6J30_RS20980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A6J30_RS20980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6J30_RS20980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A6J30_RS20985	COG2207	Transcriptional regulator
A6J30_RS20995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A6J30_RS21000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A6J30_RS21005	COG2084	Dehydrogenase
A6J30_RS21010	COG0753	catalase activity
A6J30_RS21020	COG2130	NADP-dependent
A6J30_RS21025	COG1309	transcriptional regulator
A6J30_RS21030	COG3097	Belongs to the UPF0267 family
A6J30_RS21090	COG3842	ATPase activity
A6J30_RS21105	COG1175	transmembrane transport
A6J30_RS21110	COG3833	ABC-type maltose transport systems, permease component
A6J30_RS21355	COG4792	protein secretion
A6J30_RS21385	COG3710	Transcriptional regulator
A6J30_RS21420	COG4790	Type iii secretion
A6J30_RS21520	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A6J30_RS21620	COG3746	phosphate-selective porin O and P
A6J30_RS21635	COG1028	Short-chain dehydrogenase reductase Sdr
A6J30_RS21660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A6J30_RS21670	COG0625	glutathione transferase activity
A6J30_RS21685	COG1686	Belongs to the peptidase S11 family
A6J30_RS21705	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A6J30_RS21720	COG1278	Cold shock
A6J30_RS21730	COG4667	esterase of the alpha-beta hydrolase superfamily
A6J30_RS21755	COG2814	Major facilitator Superfamily
A6J30_RS21765	COG0673	inositol 2-dehydrogenase activity
A6J30_RS21775	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A6J30_RS21785	COG2205	protein histidine kinase activity
A6J30_RS21790	COG0745	RESPONSE REGULATOR receiver
A6J30_RS21795	COG4221	oxidoreductase activity
A6J30_RS21810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A6J30_RS21835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A6J30_RS21915	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A6J30_RS21925	COG2814	Major facilitator Superfamily
A6J30_RS21935	COG1418	mRNA catabolic process
A6J30_RS21945	COG0402	S-adenosylhomocysteine deaminase activity
A6J30_RS21950	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A6J30_RS21955	COG2239	Acts as a magnesium transporter
A6J30_RS21960	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A6J30_RS21975	COG0531	amino acid
A6J30_RS21980	COG1522	sequence-specific DNA binding
A6J30_RS21985	COG0583	DNA-binding transcription factor activity
A6J30_RS22010	COG0673	inositol 2-dehydrogenase activity
A6J30_RS22015	COG0534	Mate efflux family protein
A6J30_RS22020	COG2926	Belongs to the UPF0265 family
A6J30_RS22035	COG2827	Endonuclease containing a URI domain
A6J30_RS22040	COG1879	ABC-type sugar transport system periplasmic component
A6J30_RS22045	COG2205	protein histidine kinase activity
A6J30_RS22045	COG0784	Response regulator, receiver
A6J30_RS22055	COG1566	PFAM secretion protein HlyD family protein
A6J30_RS22075	COG1522	sequence-specific DNA binding
A6J30_RS22105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A6J30_RS22110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A6J30_RS22120	COG1280	lysine exporter protein (LysE YggA)
A6J30_RS22130	COG0183	Belongs to the thiolase family
A6J30_RS22150	COG3005	denitrification pathway
A6J30_RS22160	COG0243	molybdopterin cofactor binding
A6J30_RS22170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A6J30_RS22175	COG3850	Histidine kinase
A6J30_RS22180	COG2197	response regulator
A6J30_RS22195	COG2195	Cleaves the N-terminal amino acid of tripeptides
A6J30_RS22215	COG0840	transmembrane signaling receptor activity
A6J30_RS22225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A6J30_RS22235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A6J30_RS22240	COG2814	Major facilitator Superfamily
A6J30_RS22245	COG0840	transmembrane signaling receptor activity
A6J30_RS22250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A6J30_RS22255	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A6J30_RS22285	COG2897	thiosulfate sulfurtransferase activity
A6J30_RS22300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A6J30_RS22310	COG0302	gtp cyclohydrolase
A6J30_RS22315	COG1914	H( )-stimulated, divalent metal cation uptake system
A6J30_RS22325	COG0038	chloride channel
A6J30_RS22340	COG4989	oxidoreductase activity
A6J30_RS22355	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A6J30_RS22355	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A6J30_RS22360	COG0516	GMP reductase activity
A6J30_RS22365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A6J30_RS22435	COG3474	cytochrome
A6J30_RS22445	COG0789	Transcriptional regulator
A6J30_RS22450	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A6J30_RS22455	COG0384	phenazine biosynthesis protein PhzF
A6J30_RS22465	COG1294	oxidase, subunit
A6J30_RS22470	COG1271	oxidase subunit
A6J30_RS22475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6J30_RS22480	COG0110	maltose O-acetyltransferase activity
A6J30_RS22485	COG3264	Mechanosensitive ion channel
A6J30_RS22485	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
A6J30_RS22500	COG3850	Histidine kinase
A6J30_RS22500	COG2205	protein histidine kinase activity
A6J30_RS22500	COG4999	Histidine kinase
A6J30_RS22500	COG3437	response regulator, receiver
A6J30_RS22520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A6J30_RS22525	COG1960	acyl-CoA dehydrogenase activity
A6J30_RS22535	COG0183	Belongs to the thiolase family
A6J30_RS22545	COG1960	acyl-CoA dehydrogenase activity
A6J30_RS22550	COG1024	Enoyl-CoA hydratase
A6J30_RS22565	COG1028	Short-chain dehydrogenase reductase Sdr
A6J30_RS22575	COG3706	GGDEF domain
A6J30_RS22580	COG1309	transcriptional regulator
A6J30_RS22585	COG1012	belongs to the aldehyde dehydrogenase family
A6J30_RS22600	COG4176	ABC-type proline glycine betaine transport system permease component
A6J30_RS22605	COG4175	Glycine betaine
A6J30_RS22605	COG0517	IMP dehydrogenase activity
A6J30_RS22620	COG0330	HflC and HflK could
A6J30_RS22630	COG5001	Diguanylate cyclase
A6J30_RS22630	COG3300	MHYT domain
A6J30_RS22640	COG2205	protein histidine kinase activity
A6J30_RS22640	COG0784	Response regulator, receiver
A6J30_RS22700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A6J30_RS22705	COG5001	Diguanylate cyclase
A6J30_RS22710	COG1869	D-ribose catabolic process
A6J30_RS22715	COG1129	ABC transporter
A6J30_RS22720	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6J30_RS22725	COG1879	ABC-type sugar transport system periplasmic component
A6J30_RS22730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A6J30_RS22735	COG1609	Transcriptional regulator
A6J30_RS22750	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A6J30_RS22770	COG0745	RESPONSE REGULATOR receiver
A6J30_RS22785	COG1785	Belongs to the alkaline phosphatase family
A6J30_RS22815	COG0814	amino acid
A6J30_RS22825	COG0243	molybdopterin cofactor binding
A6J30_RS22830	COG1648	precorrin-2 dehydrogenase activity
A6J30_RS22830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A6J30_RS22845	COG3707	response regulator
A6J30_RS22855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A6J30_RS22860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6J30_RS22865	COG1116	anion transmembrane transporter activity
A6J30_RS22870	COG2146	nitrite reductase [NAD(P)H] activity
A6J30_RS22870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A6J30_RS22920	COG0515	serine threonine protein kinase
A6J30_RS22920	COG2815	serine threonine protein kinase
A6J30_RS22960	COG0631	protein serine/threonine phosphatase activity
A6J30_RS23030	COG0420	3'-5' exonuclease activity
A6J30_RS23035	COG0419	ATPase involved in DNA repair
A6J30_RS23055	COG3040	lipid binding
A6J30_RS23065	COG2814	Major facilitator Superfamily
A6J30_RS23075	COG1288	antiporter activity
A6J30_RS23085	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
A6J30_RS23100	COG2425	protein containing a von Willebrand factor type A (vWA) domain
A6J30_RS23115	COG0583	DNA-binding transcription factor activity
A6J30_RS23120	COG0277	FAD linked oxidase domain protein
A6J30_RS23140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A6J30_RS23180	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A6J30_RS23180	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A6J30_RS23225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A6J30_RS23230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A6J30_RS23240	COG2116	formate transmembrane transporter activity
A6J30_RS23260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A6J30_RS23295	COG0534	Mate efflux family protein
A6J30_RS23300	COG3292	Two component regulator propeller
A6J30_RS23300	COG2205	protein histidine kinase activity
A6J30_RS23300	COG0745	RESPONSE REGULATOR receiver
A6J30_RS23310	COG3118	belongs to the thioredoxin family
A6J30_RS23315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A6J30_RS23340	COG2271	Major facilitator Superfamily
A6J30_RS23345	COG3851	Histidine kinase
A6J30_RS23350	COG2197	response regulator
A6J30_RS23360	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A6J30_RS23365	COG0583	DNA-binding transcription factor activity
A6J30_RS23375	COG0243	molybdopterin cofactor binding
A6J30_RS23380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A6J30_RS23450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A6J30_RS23470	COG1328	CTP reductase activity
A6J30_RS23475	COG0602	queuosine metabolic process
A6J30_RS23480	COG0534	Mate efflux family protein
A6J30_RS23495	COG4067	protein conserved in archaea
A6J30_RS23495	COG0189	ligase activity
A6J30_RS23505	COG3111	PFAM Bacterial OB fold (BOF) protein
A6J30_RS23510	COG1492	cobalamin metabolic process
A6J30_RS23515	COG0725	ABC transporter, periplasmic molybdate-binding protein
A6J30_RS23520	COG4149	molybdate abc transporter
A6J30_RS23525	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
A6J30_RS23535	COG5001	Diguanylate cyclase
A6J30_RS23535	COG4251	negative regulation of phosphorylation
A6J30_RS23535	COG2203	Gaf domain
A6J30_RS23535	COG3706	GGDEF domain
A6J30_RS23560	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A6J30_RS23565	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A6J30_RS23590	COG3140	Belongs to the UPF0181 family
A6J30_RS23595	COG0589	response to stress
A6J30_RS23605	COG0583	DNA-binding transcription factor activity
A6J30_RS23770	COG0045	succinate-CoA ligase (ADP-forming) activity
A6J30_RS23770	COG1042	CoA-binding domain protein
A6J30_RS23770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6J30_RS23775	COG0583	DNA-binding transcription factor activity
A6J30_RS23780	COG4771	TonB-dependent receptor
A6J30_RS23780	COG1629	transport
A6J30_RS23790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A6J30_RS23795	COG3447	MASE1 domain protein
A6J30_RS23795	COG5002	protein histidine kinase activity
A6J30_RS23795	COG5001	Diguanylate cyclase
A6J30_RS23800	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A6J30_RS23805	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A6J30_RS23810	COG1984	allophanate hydrolase subunit 2
A6J30_RS23815	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
A6J30_RS23815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6J30_RS23820	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
A6J30_RS23825	COG4181	ATPase activity
A6J30_RS23835	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A6J30_RS23840	COG5001	Diguanylate cyclase
A6J30_RS23840	COG3300	MHYT domain
A6J30_RS23850	COG0484	heat shock protein binding
A6J30_RS23885	COG2050	protein possibly involved in aromatic compounds catabolism
A6J30_RS23900	COG2067	long-chain fatty acid transport protein
A6J30_RS23905	COG2267	carboxylic ester hydrolase activity
A6J30_RS23920	COG0861	Integral membrane protein TerC family
A6J30_RS23925	COG0737	Belongs to the 5'-nucleotidase family
A6J30_RS23930	COG3593	DNA synthesis involved in DNA repair
A6J30_RS23940	COG0583	DNA-binding transcription factor activity
A6J30_RS23945	COG2116	formate transmembrane transporter activity
A6J30_RS23950	COG2353	YceI-like domain
A6J30_RS23955	COG3038	cytochrome b561
A6J30_RS23970	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A6J30_RS23975	COG0513	Belongs to the DEAD box helicase family
A6J30_RS23980	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
A6J30_RS23990	COG0840	transmembrane signaling receptor activity
A6J30_RS24000	COG0546	phosphoglycolate phosphatase activity
A6J30_RS24005	COG3437	response regulator, receiver
A6J30_RS24005	COG0784	Response regulator, receiver
A6J30_RS24020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A6J30_RS24025	COG2759	Belongs to the formate--tetrahydrofolate ligase family
A6J30_RS24030	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A6J30_RS24045	COG2207	Transcriptional regulator
A6J30_RS24050	COG1979	alcohol dehydrogenase
A6J30_RS24075	COG2271	Major facilitator Superfamily
A6J30_RS24080	COG0469	pyruvate kinase activity
A6J30_RS24085	COG1126	abc transporter atp-binding protein
A6J30_RS24090	COG0765	amino acid transport
A6J30_RS24095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6J30_RS24100	COG0765	amino acid transport
A6J30_RS24105	COG2200	EAL domain
A6J30_RS24105	COG2203	Gaf domain
A6J30_RS24105	COG2199	diguanylate cyclase activity
A6J30_RS24125	COG1609	Transcriptional regulator
A6J30_RS24130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6J30_RS24130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6J30_RS24135	COG1105	Belongs to the carbohydrate kinase PfkB family
A6J30_RS24140	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A6J30_RS24140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A6J30_RS24140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A6J30_RS24160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6J30_RS24180	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A6J30_RS24185	COG0509	glycine decarboxylation via glycine cleavage system
A6J30_RS24190	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A6J30_RS24190	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A6J30_RS24215	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
A6J30_RS24220	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A6J30_RS24225	COG0583	DNA-binding transcription factor activity
A6J30_RS24230	COG2176	DNA-directed DNA polymerase activity
A6J30_RS24275	COG0242	peptide deformylase activity
A6J30_RS24305	COG2239	Acts as a magnesium transporter
A6J30_RS24325	COG0346	lactoylglutathione lyase activity
A6J30_RS24330	COG1902	pentaerythritol trinitrate reductase activity
A6J30_RS24350	COG5642	Protein of unknown function (DUF2384)
A6J30_RS24355	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
A6J30_RS24375	COG4565	transcriptional regulatory protein
A6J30_RS24380	COG3290	protein histidine kinase activity
A6J30_RS24385	COG0471	metal ion transport
A6J30_RS24415	COG2076	Multidrug Resistance protein
A6J30_RS24430	COG0671	phosphoesterase, PA-phosphatase related
A6J30_RS24445	COG2962	Rard protein
A6J30_RS24455	COG2165	general secretion pathway protein
A6J30_RS24460	COG0784	Response regulator, receiver
A6J30_RS24460	COG0835	chemotaxis
A6J30_RS24480	COG2197	response regulator
A6J30_RS24490	COG3706	GGDEF domain
A6J30_RS24495	COG2197	response regulator
A6J30_RS24500	COG3300	MHYT domain
A6J30_RS24500	COG5001	Diguanylate cyclase
A6J30_RS24515	COG0583	DNA-binding transcription factor activity
A6J30_RS24520	COG0583	DNA-binding transcription factor activity
A6J30_RS24580	COG4964	Belongs to the GSP D family
A6J30_RS24605	COG2207	Transcriptional regulator
A6J30_RS24625	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A6J30_RS24645	COG0456	acetyltransferase
A6J30_RS24645	COG1214	PFAM Peptidase M22, glycoprotease
A6J30_RS24655	COG3069	C4-dicarboxylate transmembrane transporter activity
A6J30_RS24660	COG1704	LemA family
A6J30_RS24665	COG0501	Belongs to the peptidase M48B family
A6J30_RS24690	COG0641	radical SAM
A6J30_RS24710	COG3111	PFAM Bacterial OB fold (BOF) protein
A6J30_RS24715	COG1597	lipid kinase activity
A6J30_RS24720	COG0583	DNA-binding transcription factor activity
A6J30_RS24725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A6J30_RS24725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A6J30_RS24755	COG0714	Associated with various cellular activities
A6J30_RS24760	COG0641	radical SAM
A6J30_RS24765	COG3119	arylsulfatase activity
A6J30_RS24780	COG3119	arylsulfatase activity
A6J30_RS24785	COG3119	arylsulfatase activity
A6J30_RS24795	COG0745	RESPONSE REGULATOR receiver
A6J30_RS24810	COG2198	Histidine kinase
A6J30_RS24810	COG0784	Response regulator, receiver
A6J30_RS24810	COG2205	protein histidine kinase activity
A6J30_RS24815	COG1879	ABC-type sugar transport system periplasmic component